ngs_server 0.1 → 0.2

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Files changed (248) hide show
  1. data/bin/ngs_server +72 -50
  2. data/ext/bamtools/extconf.rb +3 -3
  3. data/ext/vcftools/Makefile +28 -0
  4. data/ext/vcftools/README.txt +36 -0
  5. data/ext/vcftools/cpp/.svn/all-wcprops +125 -0
  6. data/ext/vcftools/cpp/.svn/dir-prop-base +6 -0
  7. data/ext/vcftools/cpp/.svn/entries +708 -0
  8. data/ext/vcftools/cpp/.svn/text-base/Makefile.svn-base +46 -0
  9. data/ext/vcftools/cpp/.svn/text-base/dgeev.cpp.svn-base +146 -0
  10. data/ext/vcftools/cpp/.svn/text-base/dgeev.h.svn-base +43 -0
  11. data/ext/vcftools/cpp/.svn/text-base/output_log.cpp.svn-base +79 -0
  12. data/ext/vcftools/cpp/.svn/text-base/output_log.h.svn-base +34 -0
  13. data/ext/vcftools/cpp/.svn/text-base/parameters.cpp.svn-base +535 -0
  14. data/ext/vcftools/cpp/.svn/text-base/parameters.h.svn-base +154 -0
  15. data/ext/vcftools/cpp/.svn/text-base/vcf_entry.cpp.svn-base +497 -0
  16. data/ext/vcftools/cpp/.svn/text-base/vcf_entry.h.svn-base +190 -0
  17. data/ext/vcftools/cpp/.svn/text-base/vcf_entry_getters.cpp.svn-base +421 -0
  18. data/ext/vcftools/cpp/.svn/text-base/vcf_entry_setters.cpp.svn-base +482 -0
  19. data/ext/vcftools/cpp/.svn/text-base/vcf_file.cpp.svn-base +495 -0
  20. data/ext/vcftools/cpp/.svn/text-base/vcf_file.h.svn-base +184 -0
  21. data/ext/vcftools/cpp/.svn/text-base/vcf_file_diff.cpp.svn-base +1282 -0
  22. data/ext/vcftools/cpp/.svn/text-base/vcf_file_filters.cpp.svn-base +1215 -0
  23. data/ext/vcftools/cpp/.svn/text-base/vcf_file_format_convert.cpp.svn-base +1138 -0
  24. data/ext/vcftools/cpp/.svn/text-base/vcf_file_index.cpp.svn-base +171 -0
  25. data/ext/vcftools/cpp/.svn/text-base/vcf_file_output.cpp.svn-base +3012 -0
  26. data/ext/vcftools/cpp/.svn/text-base/vcftools.cpp.svn-base +107 -0
  27. data/ext/vcftools/cpp/.svn/text-base/vcftools.h.svn-base +25 -0
  28. data/ext/vcftools/cpp/Makefile +46 -0
  29. data/ext/vcftools/cpp/dgeev.cpp +146 -0
  30. data/ext/vcftools/cpp/dgeev.h +43 -0
  31. data/ext/vcftools/cpp/output_log.cpp +79 -0
  32. data/ext/vcftools/cpp/output_log.h +34 -0
  33. data/ext/vcftools/cpp/parameters.cpp +535 -0
  34. data/ext/vcftools/cpp/parameters.h +154 -0
  35. data/ext/vcftools/cpp/vcf_entry.cpp +497 -0
  36. data/ext/vcftools/cpp/vcf_entry.h +190 -0
  37. data/ext/vcftools/cpp/vcf_entry_getters.cpp +421 -0
  38. data/ext/vcftools/cpp/vcf_entry_setters.cpp +482 -0
  39. data/ext/vcftools/cpp/vcf_file.cpp +495 -0
  40. data/ext/vcftools/cpp/vcf_file.h +184 -0
  41. data/ext/vcftools/cpp/vcf_file_diff.cpp +1282 -0
  42. data/ext/vcftools/cpp/vcf_file_filters.cpp +1215 -0
  43. data/ext/vcftools/cpp/vcf_file_format_convert.cpp +1138 -0
  44. data/ext/vcftools/cpp/vcf_file_index.cpp +171 -0
  45. data/ext/vcftools/cpp/vcf_file_output.cpp +3012 -0
  46. data/ext/vcftools/cpp/vcftools.cpp +107 -0
  47. data/ext/vcftools/cpp/vcftools.h +25 -0
  48. data/ext/vcftools/examples/.svn/all-wcprops +185 -0
  49. data/ext/vcftools/examples/.svn/dir-prop-base +6 -0
  50. data/ext/vcftools/examples/.svn/entries +1048 -0
  51. data/ext/vcftools/examples/.svn/prop-base/perl-api-1.pl.svn-base +5 -0
  52. data/ext/vcftools/examples/.svn/text-base/annotate-test.vcf.svn-base +37 -0
  53. data/ext/vcftools/examples/.svn/text-base/annotate.out.svn-base +23 -0
  54. data/ext/vcftools/examples/.svn/text-base/annotate.txt.svn-base +7 -0
  55. data/ext/vcftools/examples/.svn/text-base/annotate2.out.svn-base +52 -0
  56. data/ext/vcftools/examples/.svn/text-base/annotate3.out.svn-base +23 -0
  57. data/ext/vcftools/examples/.svn/text-base/cmp-test-a-3.3.vcf.svn-base +12 -0
  58. data/ext/vcftools/examples/.svn/text-base/cmp-test-a.vcf.svn-base +12 -0
  59. data/ext/vcftools/examples/.svn/text-base/cmp-test-b-3.3.vcf.svn-base +12 -0
  60. data/ext/vcftools/examples/.svn/text-base/cmp-test-b.vcf.svn-base +12 -0
  61. data/ext/vcftools/examples/.svn/text-base/cmp-test.out.svn-base +53 -0
  62. data/ext/vcftools/examples/.svn/text-base/concat-a.vcf.svn-base +21 -0
  63. data/ext/vcftools/examples/.svn/text-base/concat-b.vcf.svn-base +13 -0
  64. data/ext/vcftools/examples/.svn/text-base/concat-c.vcf.svn-base +19 -0
  65. data/ext/vcftools/examples/.svn/text-base/concat.out.svn-base +39 -0
  66. data/ext/vcftools/examples/.svn/text-base/invalid-4.0.vcf.svn-base +31 -0
  67. data/ext/vcftools/examples/.svn/text-base/isec-n2-test.vcf.out.svn-base +19 -0
  68. data/ext/vcftools/examples/.svn/text-base/merge-test-a.vcf.svn-base +17 -0
  69. data/ext/vcftools/examples/.svn/text-base/merge-test-b.vcf.svn-base +17 -0
  70. data/ext/vcftools/examples/.svn/text-base/merge-test-c.vcf.svn-base +15 -0
  71. data/ext/vcftools/examples/.svn/text-base/merge-test.vcf.out.svn-base +31 -0
  72. data/ext/vcftools/examples/.svn/text-base/perl-api-1.pl.svn-base +46 -0
  73. data/ext/vcftools/examples/.svn/text-base/query-test.out.svn-base +6 -0
  74. data/ext/vcftools/examples/.svn/text-base/shuffle-test.vcf.svn-base +12 -0
  75. data/ext/vcftools/examples/.svn/text-base/subset.SNPs.out.svn-base +10 -0
  76. data/ext/vcftools/examples/.svn/text-base/subset.indels.out.svn-base +18 -0
  77. data/ext/vcftools/examples/.svn/text-base/subset.vcf.svn-base +21 -0
  78. data/ext/vcftools/examples/.svn/text-base/valid-3.3.vcf.svn-base +30 -0
  79. data/ext/vcftools/examples/.svn/text-base/valid-4.0.vcf.stats.svn-base +104 -0
  80. data/ext/vcftools/examples/.svn/text-base/valid-4.0.vcf.svn-base +34 -0
  81. data/ext/vcftools/examples/.svn/text-base/valid-4.1.vcf.svn-base +37 -0
  82. data/ext/vcftools/examples/annotate-test.vcf +37 -0
  83. data/ext/vcftools/examples/annotate.out +23 -0
  84. data/ext/vcftools/examples/annotate.txt +7 -0
  85. data/ext/vcftools/examples/annotate2.out +52 -0
  86. data/ext/vcftools/examples/annotate3.out +23 -0
  87. data/ext/vcftools/examples/cmp-test-a-3.3.vcf +12 -0
  88. data/ext/vcftools/examples/cmp-test-a.vcf +12 -0
  89. data/ext/vcftools/examples/cmp-test-b-3.3.vcf +12 -0
  90. data/ext/vcftools/examples/cmp-test-b.vcf +12 -0
  91. data/ext/vcftools/examples/cmp-test.out +53 -0
  92. data/ext/vcftools/examples/concat-a.vcf +21 -0
  93. data/ext/vcftools/examples/concat-b.vcf +13 -0
  94. data/ext/vcftools/examples/concat-c.vcf +19 -0
  95. data/ext/vcftools/examples/concat.out +39 -0
  96. data/ext/vcftools/examples/invalid-4.0.vcf +31 -0
  97. data/ext/vcftools/examples/isec-n2-test.vcf.out +19 -0
  98. data/ext/vcftools/examples/merge-test-a.vcf +17 -0
  99. data/ext/vcftools/examples/merge-test-b.vcf +17 -0
  100. data/ext/vcftools/examples/merge-test-c.vcf +15 -0
  101. data/ext/vcftools/examples/merge-test.vcf.out +31 -0
  102. data/ext/vcftools/examples/perl-api-1.pl +46 -0
  103. data/ext/vcftools/examples/query-test.out +6 -0
  104. data/ext/vcftools/examples/shuffle-test.vcf +12 -0
  105. data/ext/vcftools/examples/subset.SNPs.out +10 -0
  106. data/ext/vcftools/examples/subset.indels.out +18 -0
  107. data/ext/vcftools/examples/subset.vcf +21 -0
  108. data/ext/vcftools/examples/valid-3.3.vcf +30 -0
  109. data/ext/vcftools/examples/valid-4.0.vcf +34 -0
  110. data/ext/vcftools/examples/valid-4.0.vcf.stats +104 -0
  111. data/ext/vcftools/examples/valid-4.1.vcf +37 -0
  112. data/ext/vcftools/extconf.rb +2 -0
  113. data/ext/vcftools/perl/.svn/all-wcprops +149 -0
  114. data/ext/vcftools/perl/.svn/entries +844 -0
  115. data/ext/vcftools/perl/.svn/prop-base/fill-aa.svn-base +5 -0
  116. data/ext/vcftools/perl/.svn/prop-base/fill-an-ac.svn-base +5 -0
  117. data/ext/vcftools/perl/.svn/prop-base/fill-ref-md5.svn-base +5 -0
  118. data/ext/vcftools/perl/.svn/prop-base/tab-to-vcf.svn-base +5 -0
  119. data/ext/vcftools/perl/.svn/prop-base/test.t.svn-base +5 -0
  120. data/ext/vcftools/perl/.svn/prop-base/vcf-annotate.svn-base +5 -0
  121. data/ext/vcftools/perl/.svn/prop-base/vcf-compare.svn-base +5 -0
  122. data/ext/vcftools/perl/.svn/prop-base/vcf-concat.svn-base +5 -0
  123. data/ext/vcftools/perl/.svn/prop-base/vcf-convert.svn-base +5 -0
  124. data/ext/vcftools/perl/.svn/prop-base/vcf-fix-newlines.svn-base +5 -0
  125. data/ext/vcftools/perl/.svn/prop-base/vcf-isec.svn-base +5 -0
  126. data/ext/vcftools/perl/.svn/prop-base/vcf-merge.svn-base +5 -0
  127. data/ext/vcftools/perl/.svn/prop-base/vcf-query.svn-base +5 -0
  128. data/ext/vcftools/perl/.svn/prop-base/vcf-shuffle-cols.svn-base +5 -0
  129. data/ext/vcftools/perl/.svn/prop-base/vcf-sort.svn-base +5 -0
  130. data/ext/vcftools/perl/.svn/prop-base/vcf-stats.svn-base +5 -0
  131. data/ext/vcftools/perl/.svn/prop-base/vcf-subset.svn-base +5 -0
  132. data/ext/vcftools/perl/.svn/prop-base/vcf-to-tab.svn-base +5 -0
  133. data/ext/vcftools/perl/.svn/prop-base/vcf-validator.svn-base +5 -0
  134. data/ext/vcftools/perl/.svn/text-base/ChangeLog.svn-base +84 -0
  135. data/ext/vcftools/perl/.svn/text-base/FaSlice.pm.svn-base +214 -0
  136. data/ext/vcftools/perl/.svn/text-base/Makefile.svn-base +12 -0
  137. data/ext/vcftools/perl/.svn/text-base/Vcf.pm.svn-base +2853 -0
  138. data/ext/vcftools/perl/.svn/text-base/VcfStats.pm.svn-base +681 -0
  139. data/ext/vcftools/perl/.svn/text-base/fill-aa.svn-base +103 -0
  140. data/ext/vcftools/perl/.svn/text-base/fill-an-ac.svn-base +56 -0
  141. data/ext/vcftools/perl/.svn/text-base/fill-ref-md5.svn-base +204 -0
  142. data/ext/vcftools/perl/.svn/text-base/tab-to-vcf.svn-base +92 -0
  143. data/ext/vcftools/perl/.svn/text-base/test.t.svn-base +376 -0
  144. data/ext/vcftools/perl/.svn/text-base/vcf-annotate.svn-base +1099 -0
  145. data/ext/vcftools/perl/.svn/text-base/vcf-compare.svn-base +1193 -0
  146. data/ext/vcftools/perl/.svn/text-base/vcf-concat.svn-base +310 -0
  147. data/ext/vcftools/perl/.svn/text-base/vcf-convert.svn-base +180 -0
  148. data/ext/vcftools/perl/.svn/text-base/vcf-fix-newlines.svn-base +97 -0
  149. data/ext/vcftools/perl/.svn/text-base/vcf-isec.svn-base +660 -0
  150. data/ext/vcftools/perl/.svn/text-base/vcf-merge.svn-base +577 -0
  151. data/ext/vcftools/perl/.svn/text-base/vcf-query.svn-base +272 -0
  152. data/ext/vcftools/perl/.svn/text-base/vcf-shuffle-cols.svn-base +89 -0
  153. data/ext/vcftools/perl/.svn/text-base/vcf-sort.svn-base +79 -0
  154. data/ext/vcftools/perl/.svn/text-base/vcf-stats.svn-base +160 -0
  155. data/ext/vcftools/perl/.svn/text-base/vcf-subset.svn-base +206 -0
  156. data/ext/vcftools/perl/.svn/text-base/vcf-to-tab.svn-base +112 -0
  157. data/ext/vcftools/perl/.svn/text-base/vcf-validator.svn-base +145 -0
  158. data/ext/vcftools/perl/ChangeLog +84 -0
  159. data/ext/vcftools/perl/FaSlice.pm +214 -0
  160. data/ext/vcftools/perl/Makefile +12 -0
  161. data/ext/vcftools/perl/Vcf.pm +2853 -0
  162. data/ext/vcftools/perl/VcfStats.pm +681 -0
  163. data/ext/vcftools/perl/fill-aa +103 -0
  164. data/ext/vcftools/perl/fill-an-ac +56 -0
  165. data/ext/vcftools/perl/fill-ref-md5 +204 -0
  166. data/ext/vcftools/perl/tab-to-vcf +92 -0
  167. data/ext/vcftools/perl/test.t +376 -0
  168. data/ext/vcftools/perl/vcf-annotate +1099 -0
  169. data/ext/vcftools/perl/vcf-compare +1193 -0
  170. data/ext/vcftools/perl/vcf-concat +310 -0
  171. data/ext/vcftools/perl/vcf-convert +180 -0
  172. data/ext/vcftools/perl/vcf-fix-newlines +97 -0
  173. data/ext/vcftools/perl/vcf-isec +660 -0
  174. data/ext/vcftools/perl/vcf-merge +577 -0
  175. data/ext/vcftools/perl/vcf-query +286 -0
  176. data/ext/vcftools/perl/vcf-shuffle-cols +89 -0
  177. data/ext/vcftools/perl/vcf-sort +79 -0
  178. data/ext/vcftools/perl/vcf-stats +160 -0
  179. data/ext/vcftools/perl/vcf-subset +206 -0
  180. data/ext/vcftools/perl/vcf-to-tab +112 -0
  181. data/ext/vcftools/perl/vcf-validator +145 -0
  182. data/ext/vcftools/website/.svn/all-wcprops +41 -0
  183. data/ext/vcftools/website/.svn/entries +238 -0
  184. data/ext/vcftools/website/.svn/prop-base/VCF-poster.pdf.svn-base +5 -0
  185. data/ext/vcftools/website/.svn/prop-base/favicon.ico.svn-base +5 -0
  186. data/ext/vcftools/website/.svn/prop-base/favicon.png.svn-base +5 -0
  187. data/ext/vcftools/website/.svn/text-base/Makefile.svn-base +6 -0
  188. data/ext/vcftools/website/.svn/text-base/README.svn-base +2 -0
  189. data/ext/vcftools/website/.svn/text-base/VCF-poster.pdf.svn-base +0 -0
  190. data/ext/vcftools/website/.svn/text-base/default.css.svn-base +250 -0
  191. data/ext/vcftools/website/.svn/text-base/favicon.ico.svn-base +0 -0
  192. data/ext/vcftools/website/.svn/text-base/favicon.png.svn-base +0 -0
  193. data/ext/vcftools/website/Makefile +6 -0
  194. data/ext/vcftools/website/README +2 -0
  195. data/ext/vcftools/website/VCF-poster.pdf +0 -0
  196. data/ext/vcftools/website/default.css +250 -0
  197. data/ext/vcftools/website/favicon.ico +0 -0
  198. data/ext/vcftools/website/favicon.png +0 -0
  199. data/ext/vcftools/website/img/.svn/all-wcprops +53 -0
  200. data/ext/vcftools/website/img/.svn/entries +300 -0
  201. data/ext/vcftools/website/img/.svn/prop-base/bg.gif.svn-base +5 -0
  202. data/ext/vcftools/website/img/.svn/prop-base/bgcode.gif.svn-base +5 -0
  203. data/ext/vcftools/website/img/.svn/prop-base/bgcontainer.gif.svn-base +5 -0
  204. data/ext/vcftools/website/img/.svn/prop-base/bgul.gif.svn-base +5 -0
  205. data/ext/vcftools/website/img/.svn/prop-base/header.gif.svn-base +5 -0
  206. data/ext/vcftools/website/img/.svn/prop-base/li.gif.svn-base +5 -0
  207. data/ext/vcftools/website/img/.svn/prop-base/quote.gif.svn-base +5 -0
  208. data/ext/vcftools/website/img/.svn/prop-base/search.gif.svn-base +5 -0
  209. data/ext/vcftools/website/img/.svn/text-base/bg.gif.svn-base +0 -0
  210. data/ext/vcftools/website/img/.svn/text-base/bgcode.gif.svn-base +0 -0
  211. data/ext/vcftools/website/img/.svn/text-base/bgcontainer.gif.svn-base +0 -0
  212. data/ext/vcftools/website/img/.svn/text-base/bgul.gif.svn-base +0 -0
  213. data/ext/vcftools/website/img/.svn/text-base/header.gif.svn-base +0 -0
  214. data/ext/vcftools/website/img/.svn/text-base/li.gif.svn-base +0 -0
  215. data/ext/vcftools/website/img/.svn/text-base/quote.gif.svn-base +0 -0
  216. data/ext/vcftools/website/img/.svn/text-base/search.gif.svn-base +0 -0
  217. data/ext/vcftools/website/img/bg.gif +0 -0
  218. data/ext/vcftools/website/img/bgcode.gif +0 -0
  219. data/ext/vcftools/website/img/bgcontainer.gif +0 -0
  220. data/ext/vcftools/website/img/bgul.gif +0 -0
  221. data/ext/vcftools/website/img/header.gif +0 -0
  222. data/ext/vcftools/website/img/li.gif +0 -0
  223. data/ext/vcftools/website/img/quote.gif +0 -0
  224. data/ext/vcftools/website/img/search.gif +0 -0
  225. data/ext/vcftools/website/src/.svn/all-wcprops +53 -0
  226. data/ext/vcftools/website/src/.svn/entries +300 -0
  227. data/ext/vcftools/website/src/.svn/text-base/docs.inc.svn-base +202 -0
  228. data/ext/vcftools/website/src/.svn/text-base/index.inc.svn-base +52 -0
  229. data/ext/vcftools/website/src/.svn/text-base/index.php.svn-base +80 -0
  230. data/ext/vcftools/website/src/.svn/text-base/license.inc.svn-base +27 -0
  231. data/ext/vcftools/website/src/.svn/text-base/links.inc.svn-base +13 -0
  232. data/ext/vcftools/website/src/.svn/text-base/options.inc.svn-base +654 -0
  233. data/ext/vcftools/website/src/.svn/text-base/perl_module.inc.svn-base +249 -0
  234. data/ext/vcftools/website/src/.svn/text-base/specs.inc.svn-base +18 -0
  235. data/ext/vcftools/website/src/docs.inc +202 -0
  236. data/ext/vcftools/website/src/index.inc +52 -0
  237. data/ext/vcftools/website/src/index.php +80 -0
  238. data/ext/vcftools/website/src/license.inc +27 -0
  239. data/ext/vcftools/website/src/links.inc +13 -0
  240. data/ext/vcftools/website/src/options.inc +654 -0
  241. data/ext/vcftools/website/src/perl_module.inc +249 -0
  242. data/ext/vcftools/website/src/specs.inc +18 -0
  243. data/lib/config.ru +9 -0
  244. data/lib/ngs_server/add.rb +9 -0
  245. data/lib/ngs_server/version.rb +1 -1
  246. data/lib/ngs_server.rb +55 -3
  247. data/ngs_server.gemspec +5 -2
  248. metadata +296 -6
@@ -0,0 +1,171 @@
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+ /*
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+ * vcf_file.cpp
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+ *
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+ * Created on: 3 Aug 2011
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+ * Author: auton
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+ */
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+
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+ #include "vcf_file.h"
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+
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+ bool vcf_file::read_index_file(const string &index_filename)
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+ {
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+ // Check index is newer than vcf file
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+ struct stat stat_idx, stat_vcf;
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+ stat(index_filename.c_str(), &stat_idx);
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+ stat(filename.c_str(), &stat_vcf);
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+ if (stat_vcf.st_mtime > stat_idx.st_mtime)
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+ {
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+ warning("VCF index is older than VCF file. Will regenerate.");
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+ return false;
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+ }
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+
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+ printLOG("Reading Index file.\n");
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+ big_endian_machine = is_big_endian();
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+ gzFile in = gzopen(index_filename.c_str(), "rb");
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+ if (in == NULL)
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+ return false;
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+
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+ char magic[7];
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+ idx_read(in, magic, 7, sizeof(char));
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+ if (strncmp(magic, "VCFIDX\1", 7) != 0)
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+ { // Doesn't appear to be an index file
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+ gzclose(in);
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+ warning("Index file doesn't appear to be valid. Will (try to) overwrite.\n");
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+ return false;
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+ }
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+
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+ uint32_t tmp;
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+ uint64_t tmp64;
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+ idx_read(in, &tmp, 1, sizeof(uint32_t));
40
+ N_entries = tmp;
41
+ idx_read(in, &tmp, 1, sizeof(uint32_t));
42
+ N_indv = tmp;
43
+ idx_read(in, &tmp, 1, sizeof(uint32_t));
44
+ unsigned int l_meta = tmp;
45
+ idx_read(in, &tmp, 1, sizeof(uint32_t));
46
+ unsigned int l_indv = tmp;
47
+
48
+ char *meta_buffer = new char [l_meta+1];
49
+ char *indv_buffer = new char [l_indv+1];
50
+
51
+ idx_read(in, meta_buffer, l_meta, 1);
52
+ idx_read(in, indv_buffer, l_indv, 1);
53
+
54
+ // Split the strings
55
+ meta.resize(0);
56
+ char * pch;
57
+ pch = strtok(meta_buffer,"\n");
58
+ while (pch != NULL)
59
+ {
60
+ meta.push_back(pch);
61
+ pch = strtok(NULL, "\n");
62
+ }
63
+
64
+ indv.resize(0);
65
+ pch = strtok (indv_buffer,"\n");
66
+ while (pch != NULL)
67
+ {
68
+ indv.push_back(pch);
69
+ pch = strtok (NULL, "\n");
70
+ }
71
+
72
+ delete [] indv_buffer;
73
+ delete [] meta_buffer;
74
+
75
+ entry_file_locations.resize(N_entries);
76
+ for (unsigned int ui=0; ui<N_entries; ui++)
77
+ {
78
+ idx_read(in, &tmp64, 1, sizeof(uint64_t));
79
+ entry_file_locations[ui] = tmp64;
80
+ }
81
+
82
+ gzclose(in);
83
+ return true;
84
+ }
85
+
86
+
87
+ void vcf_file::write_index_file(const string &index_filename)
88
+ {
89
+ printLOG("Writing Index file.\n");
90
+ big_endian_machine = is_big_endian();
91
+
92
+ gzFile out = gzopen(index_filename.c_str(), "wb");
93
+ if (out == NULL)
94
+ {
95
+ warning("Could not write index file.\n");
96
+ return;
97
+ }
98
+
99
+ unsigned int l_meta = 0;
100
+ for (unsigned int ui=0; ui<meta.size(); ui++)
101
+ l_meta += meta[ui].size() + 1;
102
+
103
+ unsigned int l_indv = 0;
104
+ for (unsigned int ui=0; ui<indv.size(); ui++)
105
+ l_indv += indv[ui].size() + 1;
106
+
107
+ idx_write(out, (char*)"VCFIDX\1", 7, 1);
108
+
109
+ uint32_t tmp;
110
+ uint64_t tmp64;
111
+ tmp = N_entries; idx_write(out, &tmp, 1, sizeof(uint32_t));
112
+ tmp = N_indv; idx_write(out, &tmp, 1, sizeof(uint32_t));
113
+ tmp = l_meta; idx_write(out, &tmp, 1, sizeof(uint32_t));
114
+ tmp = l_indv; idx_write(out, &tmp, 1, sizeof(uint32_t));
115
+
116
+ for (unsigned int ui=0; ui<meta.size(); ui++)
117
+ {
118
+ string str = meta[ui] + "\n";
119
+ idx_write(out, (char*)(str.c_str()), str.size(), 1);
120
+ }
121
+
122
+ for (unsigned int ui=0; ui<indv.size(); ui++)
123
+ {
124
+ string str = indv[ui] + "\n";
125
+ idx_write(out, (char*)(str.c_str()), str.size(), 1);
126
+ }
127
+
128
+ for (unsigned int ui=0; ui<entry_file_locations.size(); ui++)
129
+ {
130
+ tmp64 = entry_file_locations[ui];
131
+ idx_write(out, &tmp64, 1, sizeof(uint64_t));
132
+ }
133
+
134
+ gzclose(out);
135
+ }
136
+
137
+
138
+ inline void vcf_file::ByteSwap(unsigned char *b, int n) const
139
+ {
140
+ int i = 0;
141
+ int j = n-1;
142
+ while (i<j)
143
+ {
144
+ swap(b[i], b[j]);
145
+ i++, j--;
146
+ }
147
+ }
148
+
149
+
150
+ int vcf_file::idx_read(gzFile &in, void *buffer, unsigned int len, size_t size)
151
+ {
152
+ int ret = gzread(in, buffer, size*len);
153
+ if ((big_endian_machine) && (size > 1)) // Note: don't bother swapping character arrays - index is defined as little endian.
154
+ {
155
+ unsigned int ui;
156
+ for (ui=0; ui<len; ui++)
157
+ ByteSwap((unsigned char *)buffer+(size*ui), size);
158
+ }
159
+ return ret;
160
+ }
161
+
162
+ void vcf_file::idx_write(gzFile &out, void *buffer, unsigned int len, size_t size)
163
+ {
164
+ if ((big_endian_machine) && (size > 1))
165
+ {
166
+ unsigned int ui;
167
+ for (ui=0; ui<len; ui++)
168
+ ByteSwap((unsigned char *)buffer+(size*ui), size);
169
+ }
170
+ gzwrite(out, buffer, size*len);
171
+ }