biointerchange 0.1.3 → 0.2.0
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- data/README.md +17 -0
- data/VERSION +1 -1
- data/generators/GOxrefify.rb +41 -0
- data/generators/rdfxml.rb +6 -4
- data/lib/biointerchange/core.rb +94 -20
- data/lib/biointerchange/genomics/gff3_feature_set.rb +11 -3
- data/lib/biointerchange/genomics/gff3_pragmas.rb +3 -3
- data/lib/biointerchange/genomics/gff3_rdf_ntriples.rb +217 -12
- data/lib/biointerchange/genomics/gff3_reader.rb +78 -20
- data/lib/biointerchange/genomics/gvf_reader.rb +9 -3
- data/lib/biointerchange/gff3o.rb +69 -55
- data/lib/biointerchange/goxref.rb +867 -0
- data/lib/biointerchange/gvf1o.rb +546 -82
- data/lib/biointerchange/textmining/text_mining_reader.rb +9 -0
- data/spec/gff3_rdfwriter_spec.rb +1 -1
- data/spec/gvf_rdfwriter_spec.rb +1 -1
- data/spec/text_mining_pdfx_xml_reader_spec.rb +3 -0
- data/spec/text_mining_pubannos_json_reader_spec.rb +4 -1
- data/supplemental/java/biointerchange/pom.xml +1 -1
- data/supplemental/java/biointerchange/src/main/java/org/biointerchange/vocabulary/GFF3O.java +93 -125
- data/supplemental/java/biointerchange/src/main/java/org/biointerchange/vocabulary/GVF1O.java +304 -205
- data/supplemental/java/biointerchange/src/main/java/org/biointerchange/vocabulary/SIO.java +4044 -4290
- data/supplemental/java/biointerchange/src/main/java/org/biointerchange/vocabulary/SOFA.java +3 -3
- data/supplemental/python/biointerchange/gff3o.py +1 -89
- data/supplemental/python/biointerchange/gvf1o.py +129 -147
- data/supplemental/python/biointerchange/sio.py +817 -46
- data/supplemental/python/biointerchange/sofa.py +543 -543
- data/supplemental/python/setup.py +1 -1
- data/web/ontologies.html +1 -3
- metadata +7 -2
| @@ -2,1829 +2,1829 @@ import rdflib | |
| 2 2 |  | 
| 3 3 | 
             
            from rdflib import Namespace
         | 
| 4 4 |  | 
| 5 | 
            -
             | 
| 5 | 
            +
            __namespace_SOFA = Namespace('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:adjacent_to')
         | 
| 6 6 |  | 
| 7 | 
            -
            def  | 
| 8 | 
            -
                return  | 
| 7 | 
            +
            def _namespace_SOFA(accession):
         | 
| 8 | 
            +
                return __namespace_SOFA[accession]
         | 
| 9 9 |  | 
| 10 | 
            -
            class  | 
| 10 | 
            +
            class SOFA:
         | 
| 11 11 |  | 
| 12 12 | 
             
                @classmethod
         | 
| 13 13 | 
             
                def adjacent_to(cls):
         | 
| 14 | 
            -
                    return  | 
| 14 | 
            +
                    return _namespace_SOFA('')
         | 
| 15 15 |  | 
| 16 16 | 
             
                @classmethod
         | 
| 17 17 | 
             
                def complete_evidence_for_feature(cls):
         | 
| 18 | 
            -
                    return  | 
| 18 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:complete_evidence_for_feature')
         | 
| 19 19 |  | 
| 20 20 | 
             
                @classmethod
         | 
| 21 21 | 
             
                def contained_by(cls):
         | 
| 22 | 
            -
                    return  | 
| 22 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:contained_by')
         | 
| 23 23 |  | 
| 24 24 | 
             
                @classmethod
         | 
| 25 25 | 
             
                def contains(cls):
         | 
| 26 | 
            -
                    return  | 
| 26 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:contains')
         | 
| 27 27 |  | 
| 28 28 | 
             
                @classmethod
         | 
| 29 29 | 
             
                def derives_from(cls):
         | 
| 30 | 
            -
                    return  | 
| 30 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:derives_from')
         | 
| 31 31 |  | 
| 32 32 | 
             
                @classmethod
         | 
| 33 33 | 
             
                def evidence_for_feature(cls):
         | 
| 34 | 
            -
                    return  | 
| 34 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:evidence_for_feature')
         | 
| 35 35 |  | 
| 36 36 | 
             
                @classmethod
         | 
| 37 37 | 
             
                def has_integral_part(cls):
         | 
| 38 | 
            -
                    return  | 
| 38 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_integral_part')
         | 
| 39 39 |  | 
| 40 40 | 
             
                @classmethod
         | 
| 41 41 | 
             
                def has_part(cls):
         | 
| 42 | 
            -
                    return  | 
| 42 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_part')
         | 
| 43 43 |  | 
| 44 44 | 
             
                @classmethod
         | 
| 45 45 | 
             
                def homologous_to(cls):
         | 
| 46 | 
            -
                    return  | 
| 46 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:homologous_to')
         | 
| 47 47 |  | 
| 48 48 | 
             
                @classmethod
         | 
| 49 49 | 
             
                def integral_part_of(cls):
         | 
| 50 | 
            -
                    return  | 
| 50 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:integral_part_of')
         | 
| 51 51 |  | 
| 52 52 | 
             
                @classmethod
         | 
| 53 53 | 
             
                def member_of(cls):
         | 
| 54 | 
            -
                    return  | 
| 54 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:member_of')
         | 
| 55 55 |  | 
| 56 56 | 
             
                @classmethod
         | 
| 57 57 | 
             
                def non_functional_homolog_of(cls):
         | 
| 58 | 
            -
                    return  | 
| 58 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:non_functional_homolog_of')
         | 
| 59 59 |  | 
| 60 60 | 
             
                @classmethod
         | 
| 61 61 | 
             
                def orthologous_to(cls):
         | 
| 62 | 
            -
                    return  | 
| 62 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:orthologous_to')
         | 
| 63 63 |  | 
| 64 64 | 
             
                @classmethod
         | 
| 65 65 | 
             
                def paralogous_to(cls):
         | 
| 66 | 
            -
                    return  | 
| 66 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:paralogous_to')
         | 
| 67 67 |  | 
| 68 68 | 
             
                @classmethod
         | 
| 69 69 | 
             
                def part_of(cls):
         | 
| 70 | 
            -
                    return  | 
| 70 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:part_of')
         | 
| 71 71 |  | 
| 72 72 | 
             
                @classmethod
         | 
| 73 73 | 
             
                def partial_evidence_for_feature(cls):
         | 
| 74 | 
            -
                    return  | 
| 74 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:partial_evidence_for_feature')
         | 
| 75 75 |  | 
| 76 76 | 
             
                @classmethod
         | 
| 77 77 | 
             
                def similar_to(cls):
         | 
| 78 | 
            -
                    return  | 
| 78 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:similar_to')
         | 
| 79 79 |  | 
| 80 80 | 
             
                @classmethod
         | 
| 81 81 | 
             
                def Sequence_Ontology(cls):
         | 
| 82 | 
            -
                    return  | 
| 82 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000000')
         | 
| 83 83 |  | 
| 84 84 | 
             
                @classmethod
         | 
| 85 85 | 
             
                def region(cls):
         | 
| 86 86 | 
             
                    """A sequence_feature with an extent greater than zero. A nucleotide region is composed of bases and a polypeptide region is composed of amino acids. (cls, SO:ke)
         | 
| 87 87 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000001)
         | 
| 88 88 | 
             
                    """
         | 
| 89 | 
            -
                    return  | 
| 89 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000001')
         | 
| 90 90 |  | 
| 91 91 | 
             
                @classmethod
         | 
| 92 92 | 
             
                def interior_coding_exon(cls):
         | 
| 93 | 
            -
                    return  | 
| 93 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000004')
         | 
| 94 94 |  | 
| 95 95 | 
             
                @classmethod
         | 
| 96 96 | 
             
                def satellite_DNA(cls):
         | 
| 97 97 | 
             
                    """The many tandem repeats (cls, identical or related) of a short basic repeating unit; many have a base composition or other property different from the genome average that allows them to be separated from the bulk (main band) genomic DNA. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
         | 
| 98 98 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000005)
         | 
| 99 99 | 
             
                    """
         | 
| 100 | 
            -
                    return  | 
| 100 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000005')
         | 
| 101 101 |  | 
| 102 102 | 
             
                @classmethod
         | 
| 103 103 | 
             
                def PCR_product(cls):
         | 
| 104 104 | 
             
                    """A region amplified by a PCR reaction. (cls, SO:ke)
         | 
| 105 105 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000006)
         | 
| 106 106 | 
             
                    """
         | 
| 107 | 
            -
                    return  | 
| 107 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000006')
         | 
| 108 108 |  | 
| 109 109 | 
             
                @classmethod
         | 
| 110 110 | 
             
                def read_pair(cls):
         | 
| 111 111 | 
             
                    """One of a pair of sequencing reads in which the two members of the pair are related by originating at either end of a clone insert. (cls, SO:ls)
         | 
| 112 112 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000007)
         | 
| 113 113 | 
             
                    """
         | 
| 114 | 
            -
                    return  | 
| 114 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000007')
         | 
| 115 115 |  | 
| 116 116 | 
             
                @classmethod
         | 
| 117 117 | 
             
                def scRNA(cls):
         | 
| 118 118 | 
             
                    """A small non coding RNA sequence, present in the cytoplasm. (cls, SO:ke)
         | 
| 119 119 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000013)
         | 
| 120 120 | 
             
                    """
         | 
| 121 | 
            -
                    return  | 
| 121 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000013')
         | 
| 122 122 |  | 
| 123 123 | 
             
                @classmethod
         | 
| 124 124 | 
             
                def match_set(cls):
         | 
| 125 125 | 
             
                    """A collection of match parts. (cls, SO:ke)
         | 
| 126 126 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000038)
         | 
| 127 127 | 
             
                    """
         | 
| 128 | 
            -
                    return  | 
| 128 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000038')
         | 
| 129 129 |  | 
| 130 130 | 
             
                @classmethod
         | 
| 131 131 | 
             
                def match_part(cls):
         | 
| 132 132 | 
             
                    """A part of a match, for example an hsp from blast is a match_part. (cls, SO:ke)
         | 
| 133 133 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000039)
         | 
| 134 134 | 
             
                    """
         | 
| 135 | 
            -
                    return  | 
| 135 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000039')
         | 
| 136 136 |  | 
| 137 137 | 
             
                @classmethod
         | 
| 138 138 | 
             
                def gene_part(cls):
         | 
| 139 139 | 
             
                    """A part of a gene, that has no other route in the ontology back to region. This concept is necessary for logical inference as these parts must have the properties of region. It also allows us to associate all the parts of genes with a gene. (cls, SO:ke)
         | 
| 140 140 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000050)
         | 
| 141 141 | 
             
                    """
         | 
| 142 | 
            -
                    return  | 
| 142 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000050')
         | 
| 143 143 |  | 
| 144 144 | 
             
                @classmethod
         | 
| 145 145 | 
             
                def operator(cls):
         | 
| 146 146 | 
             
                    """A regulatory element of an operon to which activators or repressors bind thereby effecting translation of genes in that operon. (cls, SO:ma)
         | 
| 147 147 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000057)
         | 
| 148 148 | 
             
                    """
         | 
| 149 | 
            -
                    return  | 
| 149 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000057')
         | 
| 150 150 |  | 
| 151 151 | 
             
                @classmethod
         | 
| 152 152 | 
             
                def nuclease_binding_site(cls):
         | 
| 153 153 | 
             
                    """A binding site that, of a nucleotide molecule, that interacts selectively and non-covalently with polypeptide residues of a nuclease. (cls, SO:cb)
         | 
| 154 154 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000059)
         | 
| 155 155 | 
             
                    """
         | 
| 156 | 
            -
                    return  | 
| 156 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000059')
         | 
| 157 157 |  | 
| 158 158 | 
             
                @classmethod
         | 
| 159 159 | 
             
                def transposable_element(cls):
         | 
| 160 160 | 
             
                    """A transposon or insertion sequence. An element that can insert in a variety of DNA sequences. (cls, http://www.sci.sdsu.edu/~smaloy/Glossary/T.html)
         | 
| 161 161 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000101)
         | 
| 162 162 | 
             
                    """
         | 
| 163 | 
            -
                    return  | 
| 163 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000101')
         | 
| 164 164 |  | 
| 165 165 | 
             
                @classmethod
         | 
| 166 166 | 
             
                def expressed_sequence_match(cls):
         | 
| 167 167 | 
             
                    """A match to an EST or cDNA sequence. (cls, SO:ke)
         | 
| 168 168 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000102)
         | 
| 169 169 | 
             
                    """
         | 
| 170 | 
            -
                    return  | 
| 170 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000102')
         | 
| 171 171 |  | 
| 172 172 | 
             
                @classmethod
         | 
| 173 173 | 
             
                def clone_insert_end(cls):
         | 
| 174 174 | 
             
                    """The end of the clone insert. (cls, SO:ke)
         | 
| 175 175 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000103)
         | 
| 176 176 | 
             
                    """
         | 
| 177 | 
            -
                    return  | 
| 177 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000103')
         | 
| 178 178 |  | 
| 179 179 | 
             
                @classmethod
         | 
| 180 180 | 
             
                def polypeptide(cls):
         | 
| 181 181 | 
             
                    """A sequence of amino acids linked by peptide bonds which may lack appreciable tertiary structure and may not be liable to irreversible denaturation. (cls, SO:ma)
         | 
| 182 182 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000104)
         | 
| 183 183 | 
             
                    """
         | 
| 184 | 
            -
                    return  | 
| 184 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000104')
         | 
| 185 185 |  | 
| 186 186 | 
             
                @classmethod
         | 
| 187 187 | 
             
                def sequence_variant_obs(cls):
         | 
| 188 188 | 
             
                    """A sequence_variant is a non exact copy of a sequence_feature or genome exhibiting one or more sequence_alteration. (cls, SO:ke)
         | 
| 189 189 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000109)
         | 
| 190 190 | 
             
                    """
         | 
| 191 | 
            -
                    return  | 
| 191 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000109')
         | 
| 192 192 |  | 
| 193 193 | 
             
                @classmethod
         | 
| 194 194 | 
             
                def sequence_feature(cls):
         | 
| 195 195 | 
             
                    """An extent of biological sequence. (cls, SO:ke)
         | 
| 196 196 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000110)
         | 
| 197 197 | 
             
                    """
         | 
| 198 | 
            -
                    return  | 
| 198 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000110')
         | 
| 199 199 |  | 
| 200 200 | 
             
                @classmethod
         | 
| 201 201 | 
             
                def primer(cls):
         | 
| 202 202 | 
             
                    """An oligo to which new deoxyribonucleotides can be added by DNA polymerase. (cls, SO:ke)
         | 
| 203 203 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000112)
         | 
| 204 204 | 
             
                    """
         | 
| 205 | 
            -
                    return  | 
| 205 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000112')
         | 
| 206 206 |  | 
| 207 207 | 
             
                @classmethod
         | 
| 208 208 | 
             
                def proviral_region(cls):
         | 
| 209 209 | 
             
                    """A viral sequence which has integrated into a host genome. (cls, SO:ke)
         | 
| 210 210 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000113)
         | 
| 211 211 | 
             
                    """
         | 
| 212 | 
            -
                    return  | 
| 212 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000113')
         | 
| 213 213 |  | 
| 214 214 | 
             
                @classmethod
         | 
| 215 215 | 
             
                def methylated_C(cls):
         | 
| 216 216 | 
             
                    """A methylated deoxy-cytosine. (cls, SO:ke)
         | 
| 217 217 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000114)
         | 
| 218 218 | 
             
                    """
         | 
| 219 | 
            -
                    return  | 
| 219 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000114')
         | 
| 220 220 |  | 
| 221 221 | 
             
                @classmethod
         | 
| 222 222 | 
             
                def protein_coding_primary_transcript(cls):
         | 
| 223 223 | 
             
                    """A primary transcript that, at least in part, encodes one or more proteins. (cls, SO:ke)
         | 
| 224 224 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000120)
         | 
| 225 225 | 
             
                    """
         | 
| 226 | 
            -
                    return  | 
| 226 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000120')
         | 
| 227 227 |  | 
| 228 228 | 
             
                @classmethod
         | 
| 229 229 | 
             
                def ribosome_entry_site(cls):
         | 
| 230 230 | 
             
                    """Region in mRNA where ribosome assembles. (cls, SO:ke)
         | 
| 231 231 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000139)
         | 
| 232 232 | 
             
                    """
         | 
| 233 | 
            -
                    return  | 
| 233 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000139')
         | 
| 234 234 |  | 
| 235 235 | 
             
                @classmethod
         | 
| 236 236 | 
             
                def attenuator(cls):
         | 
| 237 237 | 
             
                    """A sequence segment located within the five prime end of an mRNA that causes premature termination of translation. (cls, SO:as)
         | 
| 238 238 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000140)
         | 
| 239 239 | 
             
                    """
         | 
| 240 | 
            -
                    return  | 
| 240 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000140')
         | 
| 241 241 |  | 
| 242 242 | 
             
                @classmethod
         | 
| 243 243 | 
             
                def terminator(cls):
         | 
| 244 244 | 
             
                    """The sequence of DNA located either at the end of the transcript that causes RNA polymerase to terminate transcription. (cls, http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
         | 
| 245 245 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000141)
         | 
| 246 246 | 
             
                    """
         | 
| 247 | 
            -
                    return  | 
| 247 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000141')
         | 
| 248 248 |  | 
| 249 249 | 
             
                @classmethod
         | 
| 250 250 | 
             
                def assembly_component(cls):
         | 
| 251 251 | 
             
                    """A region of known length which may be used to manufacture a longer region. (cls, SO:ke)
         | 
| 252 252 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000143)
         | 
| 253 253 | 
             
                    """
         | 
| 254 | 
            -
                    return  | 
| 254 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000143')
         | 
| 255 255 |  | 
| 256 256 | 
             
                @classmethod
         | 
| 257 257 | 
             
                def exon(cls):
         | 
| 258 258 | 
             
                    """A region of the transcript sequence within a gene which is not removed from the primary RNA transcript by RNA splicing. (cls, SO:ke)
         | 
| 259 259 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000147)
         | 
| 260 260 | 
             
                    """
         | 
| 261 | 
            -
                    return  | 
| 261 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000147')
         | 
| 262 262 |  | 
| 263 263 | 
             
                @classmethod
         | 
| 264 264 | 
             
                def supercontig(cls):
         | 
| 265 265 | 
             
                    """One or more contigs that have been ordered and oriented using end-read information. Contains gaps that are filled with N's. (cls, SO:ls)
         | 
| 266 266 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000148)
         | 
| 267 267 | 
             
                    """
         | 
| 268 | 
            -
                    return  | 
| 268 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000148')
         | 
| 269 269 |  | 
| 270 270 | 
             
                @classmethod
         | 
| 271 271 | 
             
                def contig(cls):
         | 
| 272 272 | 
             
                    """A contiguous sequence derived from sequence assembly. Has no gaps, but may contain N's from unavailable bases. (cls, SO:ls)
         | 
| 273 273 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000149)
         | 
| 274 274 | 
             
                    """
         | 
| 275 | 
            -
                    return  | 
| 275 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000149')
         | 
| 276 276 |  | 
| 277 277 | 
             
                @classmethod
         | 
| 278 278 | 
             
                def read(cls):
         | 
| 279 279 | 
             
                    """A sequence obtained from a single sequencing experiment. Typically a read is produced when a base calling program interprets information from a chromatogram trace file produced from a sequencing machine. (cls, SO:rd)
         | 
| 280 280 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000150)
         | 
| 281 281 | 
             
                    """
         | 
| 282 | 
            -
                    return  | 
| 282 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000150')
         | 
| 283 283 |  | 
| 284 284 | 
             
                @classmethod
         | 
| 285 285 | 
             
                def clone(cls):
         | 
| 286 286 | 
             
                    """A piece of DNA that has been inserted in a vector so that it can be propagated in a host bacterium or some other organism. (cls, SO:ke)
         | 
| 287 287 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000151)
         | 
| 288 288 | 
             
                    """
         | 
| 289 | 
            -
                    return  | 
| 289 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000151')
         | 
| 290 290 |  | 
| 291 291 | 
             
                @classmethod
         | 
| 292 292 | 
             
                def deletion(cls):
         | 
| 293 293 | 
             
                    """The point at which one or more contiguous nucleotides were excised. (cls, SO:ke)
         | 
| 294 294 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000159)
         | 
| 295 295 | 
             
                    """
         | 
| 296 | 
            -
                    return  | 
| 296 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000159')
         | 
| 297 297 |  | 
| 298 298 | 
             
                @classmethod
         | 
| 299 299 | 
             
                def methylated_A(cls):
         | 
| 300 300 | 
             
                    """A modified RNA base in which adenine has been methylated. (cls, SO:ke)
         | 
| 301 301 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000161)
         | 
| 302 302 | 
             
                    """
         | 
| 303 | 
            -
                    return  | 
| 303 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000161')
         | 
| 304 304 |  | 
| 305 305 | 
             
                @classmethod
         | 
| 306 306 | 
             
                def splice_site(cls):
         | 
| 307 307 | 
             
                    """Consensus region of primary transcript bordering junction of splicing. A region that overlaps exactly 2 base and adjacent_to splice_junction. (cls, SO:cjm, SO:ke)
         | 
| 308 308 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000162)
         | 
| 309 309 | 
             
                    """
         | 
| 310 | 
            -
                    return  | 
| 310 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000162')
         | 
| 311 311 |  | 
| 312 312 | 
             
                @classmethod
         | 
| 313 313 | 
             
                def five_prime_cis_splice_site(cls):
         | 
| 314 314 | 
             
                    """Intronic 2 bp region bordering the exon, at the 5' edge of the intron. A splice_site that is downstream_adjacent_to exon and starts intron. (cls, http://www.ucl.ac.uk/~ucbhjow/b241/glossary.html, SO:cjm, SO:ke)
         | 
| 315 315 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000163)
         | 
| 316 316 | 
             
                    """
         | 
| 317 | 
            -
                    return  | 
| 317 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000163')
         | 
| 318 318 |  | 
| 319 319 | 
             
                @classmethod
         | 
| 320 320 | 
             
                def three_prime_cis_splice_site(cls):
         | 
| 321 321 | 
             
                    """Intronic 2 bp region bordering the exon, at the 3' edge of the intron. A splice_site that is upstream_adjacent_to exon and finishes intron. (cls, http://www.ucl.ac.uk/~ucbhjow/b241/glossary.html, SO:cjm, SO:ke)
         | 
| 322 322 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000164)
         | 
| 323 323 | 
             
                    """
         | 
| 324 | 
            -
                    return  | 
| 324 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000164')
         | 
| 325 325 |  | 
| 326 326 | 
             
                @classmethod
         | 
| 327 327 | 
             
                def enhancer(cls):
         | 
| 328 328 | 
             
                    """A cis-acting sequence that increases the utilization of (cls, some) eukaryotic promoters, and can function in either orientation and in any location (upstream or downstream) relative to the promoter. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
         | 
| 329 329 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000165)
         | 
| 330 330 | 
             
                    """
         | 
| 331 | 
            -
                    return  | 
| 331 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000165')
         | 
| 332 332 |  | 
| 333 333 | 
             
                @classmethod
         | 
| 334 334 | 
             
                def promoter(cls):
         | 
| 335 335 | 
             
                    """A regulatory_region composed of the TSS(cls, s) and binding sites for TF_complexes of the basal transcription machinery. (SO:regcreative)
         | 
| 336 336 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000167)
         | 
| 337 337 | 
             
                    """
         | 
| 338 | 
            -
                    return  | 
| 338 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000167')
         | 
| 339 339 |  | 
| 340 340 | 
             
                @classmethod
         | 
| 341 341 | 
             
                def cross_genome_match(cls):
         | 
| 342 342 | 
             
                    """A nucleotide match against a sequence from another organism. (cls, SO:ma)
         | 
| 343 343 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000177)
         | 
| 344 344 | 
             
                    """
         | 
| 345 | 
            -
                    return  | 
| 345 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000177')
         | 
| 346 346 |  | 
| 347 347 | 
             
                @classmethod
         | 
| 348 348 | 
             
                def operon(cls):
         | 
| 349 349 | 
             
                    """A group of contiguous genes transcribed as a single (cls, polycistronic) mRNA from a single regulatory region. (SO:ma)
         | 
| 350 350 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000178)
         | 
| 351 351 | 
             
                    """
         | 
| 352 | 
            -
                    return  | 
| 352 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000178')
         | 
| 353 353 |  | 
| 354 354 | 
             
                @classmethod
         | 
| 355 355 | 
             
                def clone_insert_start(cls):
         | 
| 356 356 | 
             
                    """The start of the clone insert. (cls, SO:ke)
         | 
| 357 357 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000179)
         | 
| 358 358 | 
             
                    """
         | 
| 359 | 
            -
                    return  | 
| 359 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000179')
         | 
| 360 360 |  | 
| 361 361 | 
             
                @classmethod
         | 
| 362 362 | 
             
                def translated_nucleotide_match(cls):
         | 
| 363 363 | 
             
                    """A match against a translated sequence. (cls, SO:ke)
         | 
| 364 364 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000181)
         | 
| 365 365 | 
             
                    """
         | 
| 366 | 
            -
                    return  | 
| 366 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000181')
         | 
| 367 367 |  | 
| 368 368 | 
             
                @classmethod
         | 
| 369 369 | 
             
                def non_transcribed_region(cls):
         | 
| 370 370 | 
             
                    """A region of the gene which is not transcribed. (cls, SO:ke)
         | 
| 371 371 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000183)
         | 
| 372 372 | 
             
                    """
         | 
| 373 | 
            -
                    return  | 
| 373 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000183')
         | 
| 374 374 |  | 
| 375 375 | 
             
                @classmethod
         | 
| 376 376 | 
             
                def primary_transcript(cls):
         | 
| 377 377 | 
             
                    """A transcript that in its initial state requires modification to be functional. (cls, SO:ma)
         | 
| 378 378 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000185)
         | 
| 379 379 | 
             
                    """
         | 
| 380 | 
            -
                    return  | 
| 380 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000185')
         | 
| 381 381 |  | 
| 382 382 | 
             
                @classmethod
         | 
| 383 383 | 
             
                def repeat_family(cls):
         | 
| 384 384 | 
             
                    """A group of characterized repeat sequences. (cls, SO:ke)
         | 
| 385 385 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000187)
         | 
| 386 386 | 
             
                    """
         | 
| 387 | 
            -
                    return  | 
| 387 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000187')
         | 
| 388 388 |  | 
| 389 389 | 
             
                @classmethod
         | 
| 390 390 | 
             
                def intron(cls):
         | 
| 391 391 | 
             
                    """A region of a primary transcript that is transcribed, but removed from within the transcript by splicing together the sequences (cls, exons) on either side of it. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
         | 
| 392 392 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000188)
         | 
| 393 393 | 
             
                    """
         | 
| 394 | 
            -
                    return  | 
| 394 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000188')
         | 
| 395 395 |  | 
| 396 396 | 
             
                @classmethod
         | 
| 397 397 | 
             
                def RFLP_fragment(cls):
         | 
| 398 398 | 
             
                    """A DNA fragment used as a reagent to detect the polymorphic genomic loci by hybridizing against the genomic DNA digested with a given restriction enzyme. (cls, GOC:pj)
         | 
| 399 399 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000193)
         | 
| 400 400 | 
             
                    """
         | 
| 401 | 
            -
                    return  | 
| 401 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000193')
         | 
| 402 402 |  | 
| 403 403 | 
             
                @classmethod
         | 
| 404 404 | 
             
                def coding_exon(cls):
         | 
| 405 405 | 
             
                    """An exon whereby at least one base is part of a codon (cls, here, 'codon' is inclusive of the stop_codon). (SO:ke)
         | 
| 406 406 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000195)
         | 
| 407 407 | 
             
                    """
         | 
| 408 | 
            -
                    return  | 
| 408 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000195')
         | 
| 409 409 |  | 
| 410 410 | 
             
                @classmethod
         | 
| 411 411 | 
             
                def five_prime_coding_exon_coding_region(cls):
         | 
| 412 412 | 
             
                    """The sequence of the five_prime_coding_exon that codes for protein. (cls, SO:cjm)
         | 
| 413 413 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000196)
         | 
| 414 414 | 
             
                    """
         | 
| 415 | 
            -
                    return  | 
| 415 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000196')
         | 
| 416 416 |  | 
| 417 417 | 
             
                @classmethod
         | 
| 418 418 | 
             
                def three_prime_coding_exon_coding_region(cls):
         | 
| 419 419 | 
             
                    """The sequence of the three_prime_coding_exon that codes for protein. (cls, SO:cjm)
         | 
| 420 420 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000197)
         | 
| 421 421 | 
             
                    """
         | 
| 422 | 
            -
                    return  | 
| 422 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000197')
         | 
| 423 423 |  | 
| 424 424 | 
             
                @classmethod
         | 
| 425 425 | 
             
                def noncoding_exon(cls):
         | 
| 426 426 | 
             
                    """An exon that does not contain any codons. (cls, SO:ke)
         | 
| 427 427 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000198)
         | 
| 428 428 | 
             
                    """
         | 
| 429 | 
            -
                    return  | 
| 429 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000198')
         | 
| 430 430 |  | 
| 431 431 | 
             
                @classmethod
         | 
| 432 432 | 
             
                def five_prime_coding_exon(cls):
         | 
| 433 433 | 
             
                    """The 5' most coding exon. (cls, SO:ke)
         | 
| 434 434 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000200)
         | 
| 435 435 | 
             
                    """
         | 
| 436 | 
            -
                    return  | 
| 436 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000200')
         | 
| 437 437 |  | 
| 438 438 | 
             
                @classmethod
         | 
| 439 439 | 
             
                def UTR(cls):
         | 
| 440 440 | 
             
                    """Messenger RNA sequences that are untranslated and lie five prime or three prime to sequences which are translated. (cls, SO:ke)
         | 
| 441 441 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000203)
         | 
| 442 442 | 
             
                    """
         | 
| 443 | 
            -
                    return  | 
| 443 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000203')
         | 
| 444 444 |  | 
| 445 445 | 
             
                @classmethod
         | 
| 446 446 | 
             
                def five_prime_UTR(cls):
         | 
| 447 447 | 
             
                    """A region at the 5' end of a mature transcript (cls, preceding the initiation codon) that is not translated into a protein. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
         | 
| 448 448 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000204)
         | 
| 449 449 | 
             
                    """
         | 
| 450 | 
            -
                    return  | 
| 450 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000204')
         | 
| 451 451 |  | 
| 452 452 | 
             
                @classmethod
         | 
| 453 453 | 
             
                def three_prime_UTR(cls):
         | 
| 454 454 | 
             
                    """A region at the 3' end of a mature transcript (cls, following the stop codon) that is not translated into a protein. (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
         | 
| 455 455 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000205)
         | 
| 456 456 | 
             
                    """
         | 
| 457 | 
            -
                    return  | 
| 457 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000205')
         | 
| 458 458 |  | 
| 459 459 | 
             
                @classmethod
         | 
| 460 460 | 
             
                def rRNA_primary_transcript(cls):
         | 
| 461 461 | 
             
                    """A primary transcript encoding a ribosomal RNA. (cls, SO:ke)
         | 
| 462 462 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000209)
         | 
| 463 463 | 
             
                    """
         | 
| 464 | 
            -
                    return  | 
| 464 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000209')
         | 
| 465 465 |  | 
| 466 466 | 
             
                @classmethod
         | 
| 467 467 | 
             
                def mature_transcript(cls):
         | 
| 468 468 | 
             
                    """A transcript which has undergone the necessary modifications, if any, for its function. In eukaryotes this includes, for example, processing of introns, cleavage, base modification, and modifications to the 5' and/or the 3' ends, other than addition of bases. In bacteria functional mRNAs are usually not modified. (cls, SO:ke)
         | 
| 469 469 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000233)
         | 
| 470 470 | 
             
                    """
         | 
| 471 | 
            -
                    return  | 
| 471 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000233')
         | 
| 472 472 |  | 
| 473 473 | 
             
                @classmethod
         | 
| 474 474 | 
             
                def mRNA(cls):
         | 
| 475 475 | 
             
                    """Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns. (cls, SO:ma)
         | 
| 476 476 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000234)
         | 
| 477 477 | 
             
                    """
         | 
| 478 | 
            -
                    return  | 
| 478 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000234')
         | 
| 479 479 |  | 
| 480 480 | 
             
                @classmethod
         | 
| 481 481 | 
             
                def TF_binding_site(cls):
         | 
| 482 482 | 
             
                    """A region of a nucleotide molecule that binds a Transcription Factor or Transcription Factor complex [GO:0005667]. (cls, SO:ke)
         | 
| 483 483 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000235)
         | 
| 484 484 | 
             
                    """
         | 
| 485 | 
            -
                    return  | 
| 485 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000235')
         | 
| 486 486 |  | 
| 487 487 | 
             
                @classmethod
         | 
| 488 488 | 
             
                def ORF(cls):
         | 
| 489 489 | 
             
                    """The in-frame interval between the stop codons of a reading frame which when read as sequential triplets, has the potential of encoding a sequential string of amino acids. TER(cls, NNN)nTER. (SGD:rb, SO:ma)
         | 
| 490 490 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000236)
         | 
| 491 491 | 
             
                    """
         | 
| 492 | 
            -
                    return  | 
| 492 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000236')
         | 
| 493 493 |  | 
| 494 494 | 
             
                @classmethod
         | 
| 495 495 | 
             
                def flanking_region(cls):
         | 
| 496 496 | 
             
                    """The sequences extending on either side of a specific region. (cls, SO:ke)
         | 
| 497 497 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000239)
         | 
| 498 498 | 
             
                    """
         | 
| 499 | 
            -
                    return  | 
| 499 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000239')
         | 
| 500 500 |  | 
| 501 501 | 
             
                @classmethod
         | 
| 502 502 | 
             
                def rRNA(cls):
         | 
| 503 503 | 
             
                    """RNA that comprises part of a ribosome, and that can provide both structural scaffolding and catalytic activity. (cls, http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html, ISBN:0198506732)
         | 
| 504 504 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000252)
         | 
| 505 505 | 
             
                    """
         | 
| 506 | 
            -
                    return  | 
| 506 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000252')
         | 
| 507 507 |  | 
| 508 508 | 
             
                @classmethod
         | 
| 509 509 | 
             
                def tRNA(cls):
         | 
| 510 510 | 
             
                    """Transfer RNA (cls, tRNA) molecules are approximately 80 nucleotides in length. Their secondary structure includes four short double-helical elements and three loops (D, anti-codon, and T loops). Further hydrogen bonds mediate the characteristic L-shaped molecular structure. Transfer RNAs have two regions of fundamental functional importance: the anti-codon, which is responsible for specific mRNA codon recognition, and the 3' end, to which the tRNA's corresponding amino acid is attached (by aminoacyl-tRNA synthetases). Transfer RNAs cope with the degeneracy of the genetic code in two manners: having more than one tRNA (with a specific anti-codon) for a particular amino acid; and 'wobble' base-pairing, i.e. permitting non-standard base-pairing at the 3rd anti-codon position. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00005, ISBN:0198506732)
         | 
| 511 511 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000253)
         | 
| 512 512 | 
             
                    """
         | 
| 513 | 
            -
                    return  | 
| 513 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000253')
         | 
| 514 514 |  | 
| 515 515 | 
             
                @classmethod
         | 
| 516 516 | 
             
                def snRNA(cls):
         | 
| 517 517 | 
             
                    """A small nuclear RNA molecule involved in pre-mRNA splicing and processing. (cls, http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html, PMID:11733745, WB:ems)
         | 
| 518 518 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000274)
         | 
| 519 519 | 
             
                    """
         | 
| 520 | 
            -
                    return  | 
| 520 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000274')
         | 
| 521 521 |  | 
| 522 522 | 
             
                @classmethod
         | 
| 523 523 | 
             
                def snoRNA(cls):
         | 
| 524 524 | 
             
                    """A snoRNA (cls, small nucleolar RNA) is any one of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA. (GOC:kgc)
         | 
| 525 525 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000275)
         | 
| 526 526 | 
             
                    """
         | 
| 527 | 
            -
                    return  | 
| 527 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000275')
         | 
| 528 528 |  | 
| 529 529 | 
             
                @classmethod
         | 
| 530 530 | 
             
                def miRNA(cls):
         | 
| 531 531 | 
             
                    """Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (cls, SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors. (PMID:12592000)
         | 
| 532 532 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000276)
         | 
| 533 533 | 
             
                    """
         | 
| 534 | 
            -
                    return  | 
| 534 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000276')
         | 
| 535 535 |  | 
| 536 536 | 
             
                @classmethod
         | 
| 537 537 | 
             
                def microsatellite(cls):
         | 
| 538 538 | 
             
                    """A repeat_region containing repeat_units (cls, 2 to 4 bp) that is repeated multiple times in tandem. (http://www.informatics.jax.org/silver/glossary.shtml)
         | 
| 539 539 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000289)
         | 
| 540 540 | 
             
                    """
         | 
| 541 | 
            -
                    return  | 
| 541 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000289')
         | 
| 542 542 |  | 
| 543 543 | 
             
                @classmethod
         | 
| 544 544 | 
             
                def inverted_repeat(cls):
         | 
| 545 545 | 
             
                    """The sequence is complementarily repeated on the opposite strand. It is a palindrome, and it may, or may not be hyphenated. Examples: GCTGATCAGC, or GCTGA-----TCAGC. (cls, SO:ke)
         | 
| 546 546 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000294)
         | 
| 547 547 | 
             
                    """
         | 
| 548 | 
            -
                    return  | 
| 548 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000294')
         | 
| 549 549 |  | 
| 550 550 | 
             
                @classmethod
         | 
| 551 551 | 
             
                def origin_of_replication(cls):
         | 
| 552 552 | 
             
                    """The origin of replication; starting site for duplication of a nucleic acid molecule to give two identical copies. (cls, http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
         | 
| 553 553 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000296)
         | 
| 554 554 | 
             
                    """
         | 
| 555 | 
            -
                    return  | 
| 555 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000296')
         | 
| 556 556 |  | 
| 557 557 | 
             
                @classmethod
         | 
| 558 558 | 
             
                def clip(cls):
         | 
| 559 559 | 
             
                    """Part of the primary transcript that is clipped off during processing. (cls, SO:ke)
         | 
| 560 560 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000303)
         | 
| 561 561 | 
             
                    """
         | 
| 562 | 
            -
                    return  | 
| 562 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000303')
         | 
| 563 563 |  | 
| 564 564 | 
             
                @classmethod
         | 
| 565 565 | 
             
                def modified_base(cls):
         | 
| 566 566 | 
             
                    """A modified nucleotide, i.e. a nucleotide other than A, T, C. G. (cls, http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
         | 
| 567 567 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000305)
         | 
| 568 568 | 
             
                    """
         | 
| 569 | 
            -
                    return  | 
| 569 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000305')
         | 
| 570 570 |  | 
| 571 571 | 
             
                @classmethod
         | 
| 572 572 | 
             
                def methylated_base_feature(cls):
         | 
| 573 573 | 
             
                    """A nucleotide modified by methylation. (cls, SO:ke)
         | 
| 574 574 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000306)
         | 
| 575 575 | 
             
                    """
         | 
| 576 | 
            -
                    return  | 
| 576 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000306')
         | 
| 577 577 |  | 
| 578 578 | 
             
                @classmethod
         | 
| 579 579 | 
             
                def CpG_island(cls):
         | 
| 580 580 | 
             
                    """Regions of a few hundred to a few thousand bases in vertebrate genomes that are relatively GC and CpG rich; they are typically unmethylated and often found near the 5' ends of genes. (cls, SO:rd)
         | 
| 581 581 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000307)
         | 
| 582 582 | 
             
                    """
         | 
| 583 | 
            -
                    return  | 
| 583 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000307')
         | 
| 584 584 |  | 
| 585 585 | 
             
                @classmethod
         | 
| 586 586 | 
             
                def direct_repeat(cls):
         | 
| 587 587 | 
             
                    """A repeat where the same sequence is repeated in the same direction. Example: GCTGA-----GCTGA. (cls, SO:ke)
         | 
| 588 588 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000314)
         | 
| 589 589 | 
             
                    """
         | 
| 590 | 
            -
                    return  | 
| 590 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000314')
         | 
| 591 591 |  | 
| 592 592 | 
             
                @classmethod
         | 
| 593 593 | 
             
                def TSS(cls):
         | 
| 594 594 | 
             
                    """The first base where RNA polymerase begins to synthesize the RNA transcript. (cls, SO:ke)
         | 
| 595 595 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000315)
         | 
| 596 596 | 
             
                    """
         | 
| 597 | 
            -
                    return  | 
| 597 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000315')
         | 
| 598 598 |  | 
| 599 599 | 
             
                @classmethod
         | 
| 600 600 | 
             
                def CDS(cls):
         | 
| 601 601 | 
             
                    """A contiguous sequence which begins with, and includes, a start codon and ends with, and includes, a stop codon. (cls, SO:ma)
         | 
| 602 602 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000316)
         | 
| 603 603 | 
             
                    """
         | 
| 604 | 
            -
                    return  | 
| 604 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000316')
         | 
| 605 605 |  | 
| 606 606 | 
             
                @classmethod
         | 
| 607 607 | 
             
                def start_codon(cls):
         | 
| 608 608 | 
             
                    """First codon to be translated by a ribosome. (cls, SO:ke)
         | 
| 609 609 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000318)
         | 
| 610 610 | 
             
                    """
         | 
| 611 | 
            -
                    return  | 
| 611 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000318')
         | 
| 612 612 |  | 
| 613 613 | 
             
                @classmethod
         | 
| 614 614 | 
             
                def stop_codon(cls):
         | 
| 615 615 | 
             
                    """In mRNA, a set of three nucleotides that indicates the end of information for protein synthesis. (cls, SO:ke)
         | 
| 616 616 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000319)
         | 
| 617 617 | 
             
                    """
         | 
| 618 | 
            -
                    return  | 
| 618 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000319')
         | 
| 619 619 |  | 
| 620 620 | 
             
                @classmethod
         | 
| 621 621 | 
             
                def tag(cls):
         | 
| 622 622 | 
             
                    """A nucleotide sequence that may be used to identify a larger sequence. (cls, SO:ke)
         | 
| 623 623 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000324)
         | 
| 624 624 | 
             
                    """
         | 
| 625 | 
            -
                    return  | 
| 625 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000324')
         | 
| 626 626 |  | 
| 627 627 | 
             
                @classmethod
         | 
| 628 628 | 
             
                def rRNA_large_subunit_primary_transcript(cls):
         | 
| 629 629 | 
             
                    """A primary transcript encoding a large ribosomal subunit RNA. (cls, SO:ke)
         | 
| 630 630 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000325)
         | 
| 631 631 | 
             
                    """
         | 
| 632 | 
            -
                    return  | 
| 632 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000325')
         | 
| 633 633 |  | 
| 634 634 | 
             
                @classmethod
         | 
| 635 635 | 
             
                def SAGE_tag(cls):
         | 
| 636 636 | 
             
                    """A short diagnostic sequence tag, serial analysis of gene expression (cls, SAGE), that allows the quantitative and simultaneous analysis of a large number of transcripts. (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7570003&dopt=Abstract)
         | 
| 637 637 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000326)
         | 
| 638 638 | 
             
                    """
         | 
| 639 | 
            -
                    return  | 
| 639 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000326')
         | 
| 640 640 |  | 
| 641 641 | 
             
                @classmethod
         | 
| 642 642 | 
             
                def conserved_region(cls):
         | 
| 643 643 | 
             
                    """Region of sequence similarity by descent from a common ancestor. (cls, SO:ke)
         | 
| 644 644 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000330)
         | 
| 645 645 | 
             
                    """
         | 
| 646 | 
            -
                    return  | 
| 646 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000330')
         | 
| 647 647 |  | 
| 648 648 | 
             
                @classmethod
         | 
| 649 649 | 
             
                def STS(cls):
         | 
| 650 650 | 
             
                    """Short (cls, typically a few hundred base pairs) DNA sequence that has a single occurrence in a genome and whose location and base sequence are known. (http://www.biospace.com)
         | 
| 651 651 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000331)
         | 
| 652 652 | 
             
                    """
         | 
| 653 | 
            -
                    return  | 
| 653 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000331')
         | 
| 654 654 |  | 
| 655 655 | 
             
                @classmethod
         | 
| 656 656 | 
             
                def coding_conserved_region(cls):
         | 
| 657 657 | 
             
                    """Coding region of sequence similarity by descent from a common ancestor. (cls, SO:ke)
         | 
| 658 658 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000332)
         | 
| 659 659 | 
             
                    """
         | 
| 660 | 
            -
                    return  | 
| 660 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000332')
         | 
| 661 661 |  | 
| 662 662 | 
             
                @classmethod
         | 
| 663 663 | 
             
                def exon_junction(cls):
         | 
| 664 664 | 
             
                    """The boundary between two exons in a processed transcript. (cls, SO:ke)
         | 
| 665 665 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000333)
         | 
| 666 666 | 
             
                    """
         | 
| 667 | 
            -
                    return  | 
| 667 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000333')
         | 
| 668 668 |  | 
| 669 669 | 
             
                @classmethod
         | 
| 670 670 | 
             
                def nc_conserved_region(cls):
         | 
| 671 671 | 
             
                    """Non-coding region of sequence similarity by descent from a common ancestor. (cls, SO:ke)
         | 
| 672 672 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000334)
         | 
| 673 673 | 
             
                    """
         | 
| 674 | 
            -
                    return  | 
| 674 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000334')
         | 
| 675 675 |  | 
| 676 676 | 
             
                @classmethod
         | 
| 677 677 | 
             
                def pseudogene(cls):
         | 
| 678 678 | 
             
                    """A sequence that closely resembles a known functional gene, at another locus within a genome, that is non-functional as a consequence of (cls, usually several) mutations that prevent either its transcription or translation (or both). In general, pseudogenes result from either reverse transcription of a transcript of their \"normal\" paralog (SO:0000043) (in which case the pseudogene typically lacks introns and includes a poly(A) tail) or from recombination (SO:0000044) (in which case the pseudogene is typically a tandem duplication of its \"normal\" paralog). (http://www.ucl.ac.uk/~ucbhjow/b241/glossary.html)
         | 
| 679 679 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000336)
         | 
| 680 680 | 
             
                    """
         | 
| 681 | 
            -
                    return  | 
| 681 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000336')
         | 
| 682 682 |  | 
| 683 683 | 
             
                @classmethod
         | 
| 684 684 | 
             
                def RNAi_reagent(cls):
         | 
| 685 685 | 
             
                    """A double stranded RNA duplex, at least 20bp long, used experimentally to inhibit gene function by RNA interference. (cls, SO:rd)
         | 
| 686 686 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000337)
         | 
| 687 687 | 
             
                    """
         | 
| 688 | 
            -
                    return  | 
| 688 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000337')
         | 
| 689 689 |  | 
| 690 690 | 
             
                @classmethod
         | 
| 691 691 | 
             
                def chromosome(cls):
         | 
| 692 692 | 
             
                    """Structural unit composed of a nucleic acid molecule which controls its own replication through the interaction of specific proteins at one or more origins of replication. (cls, SO:ma)
         | 
| 693 693 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000340)
         | 
| 694 694 | 
             
                    """
         | 
| 695 | 
            -
                    return  | 
| 695 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000340')
         | 
| 696 696 |  | 
| 697 697 | 
             
                @classmethod
         | 
| 698 698 | 
             
                def chromosome_band(cls):
         | 
| 699 699 | 
             
                    """A cytologically distinguishable feature of a chromosome, often made visible by staining, and usually alternating light and dark. (cls, SO:ma)
         | 
| 700 700 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000341)
         | 
| 701 701 | 
             
                    """
         | 
| 702 | 
            -
                    return  | 
| 702 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000341')
         | 
| 703 703 |  | 
| 704 704 | 
             
                @classmethod
         | 
| 705 705 | 
             
                def match(cls):
         | 
| 706 706 | 
             
                    """A region of sequence, aligned to another sequence with some statistical significance, using an algorithm such as BLAST or SIM4. (cls, SO:ke)
         | 
| 707 707 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000343)
         | 
| 708 708 | 
             
                    """
         | 
| 709 | 
            -
                    return  | 
| 709 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000343')
         | 
| 710 710 |  | 
| 711 711 | 
             
                @classmethod
         | 
| 712 712 | 
             
                def splice_enhancer(cls):
         | 
| 713 713 | 
             
                    """Region of a transcript that regulates splicing. (cls, SO:ke)
         | 
| 714 714 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000344)
         | 
| 715 715 | 
             
                    """
         | 
| 716 | 
            -
                    return  | 
| 716 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000344')
         | 
| 717 717 |  | 
| 718 718 | 
             
                @classmethod
         | 
| 719 719 | 
             
                def EST(cls):
         | 
| 720 720 | 
             
                    """A tag produced from a single sequencing read from a cDNA clone or PCR product; typically a few hundred base pairs long. (cls, SO:ke)
         | 
| 721 721 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000345)
         | 
| 722 722 | 
             
                    """
         | 
| 723 | 
            -
                    return  | 
| 723 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000345')
         | 
| 724 724 |  | 
| 725 725 | 
             
                @classmethod
         | 
| 726 726 | 
             
                def nucleotide_match(cls):
         | 
| 727 727 | 
             
                    """A match against a nucleotide sequence. (cls, SO:ke)
         | 
| 728 728 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000347)
         | 
| 729 729 | 
             
                    """
         | 
| 730 | 
            -
                    return  | 
| 730 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000347')
         | 
| 731 731 |  | 
| 732 732 | 
             
                @classmethod
         | 
| 733 733 | 
             
                def protein_match(cls):
         | 
| 734 734 | 
             
                    """A match against a protein sequence. (cls, SO:ke)
         | 
| 735 735 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000349)
         | 
| 736 736 | 
             
                    """
         | 
| 737 | 
            -
                    return  | 
| 737 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000349')
         | 
| 738 738 |  | 
| 739 739 | 
             
                @classmethod
         | 
| 740 740 | 
             
                def sequence_assembly(cls):
         | 
| 741 741 | 
             
                    """A sequence of nucleotides that has been algorithmically derived from an alignment of two or more different sequences. (cls, SO:ma)
         | 
| 742 742 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000353)
         | 
| 743 743 | 
             
                    """
         | 
| 744 | 
            -
                    return  | 
| 744 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000353')
         | 
| 745 745 |  | 
| 746 746 | 
             
                @classmethod
         | 
| 747 747 | 
             
                def codon(cls):
         | 
| 748 748 | 
             
                    """A set of (cls, usually) three nucleotide bases in a DNA or RNA sequence, which together code for a unique amino acid or the termination of translation and are contained within the CDS. (http://www.everythingbio.com/glos/definition.php?word=codon, SO:ke)
         | 
| 749 749 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000360)
         | 
| 750 750 | 
             
                    """
         | 
| 751 | 
            -
                    return  | 
| 751 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000360')
         | 
| 752 752 |  | 
| 753 753 | 
             
                @classmethod
         | 
| 754 754 | 
             
                def insertion_site(cls):
         | 
| 755 755 | 
             
                    """The junction where an insertion occurred. (cls, SO:ke)
         | 
| 756 756 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000366)
         | 
| 757 757 | 
             
                    """
         | 
| 758 | 
            -
                    return  | 
| 758 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000366')
         | 
| 759 759 |  | 
| 760 760 | 
             
                @classmethod
         | 
| 761 761 | 
             
                def transposable_element_insertion_site(cls):
         | 
| 762 762 | 
             
                    """The junction in a genome where a transposable_element has inserted. (cls, SO:ke)
         | 
| 763 763 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000368)
         | 
| 764 764 | 
             
                    """
         | 
| 765 | 
            -
                    return  | 
| 765 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000368')
         | 
| 766 766 |  | 
| 767 767 | 
             
                @classmethod
         | 
| 768 768 | 
             
                def small_regulatory_ncRNA(cls):
         | 
| 769 769 | 
             
                    """A non-coding RNA, usually with a specific secondary structure, that acts to regulate gene expression. (cls, SO:ma)
         | 
| 770 770 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000370)
         | 
| 771 771 | 
             
                    """
         | 
| 772 | 
            -
                    return  | 
| 772 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000370')
         | 
| 773 773 |  | 
| 774 774 | 
             
                @classmethod
         | 
| 775 775 | 
             
                def enzymatic_RNA(cls):
         | 
| 776 776 | 
             
                    """An RNA sequence that has catalytic activity with or without an associated ribonucleoprotein. (cls, RSC:cb)
         | 
| 777 777 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000372)
         | 
| 778 778 | 
             
                    """
         | 
| 779 | 
            -
                    return  | 
| 779 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000372')
         | 
| 780 780 |  | 
| 781 781 | 
             
                @classmethod
         | 
| 782 782 | 
             
                def ribozyme(cls):
         | 
| 783 783 | 
             
                    """An RNA with catalytic activity. (cls, SO:ma)
         | 
| 784 784 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000374)
         | 
| 785 785 | 
             
                    """
         | 
| 786 | 
            -
                    return  | 
| 786 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000374')
         | 
| 787 787 |  | 
| 788 788 | 
             
                @classmethod
         | 
| 789 789 | 
             
                def rRNA_5_8S(cls):
         | 
| 790 790 | 
             
                    """5_8S ribosomal RNA (cls, 5. 8S rRNA) is a component of the large subunit of the eukaryotic ribosome. It is transcribed by RNA polymerase I as part of the 45S precursor that also contains 18S and 28S rRNA. Functionally, it is thought that 5.8S rRNA may be involved in ribosome translocation. It is also known to form covalent linkage to the p53 tumour suppressor protein. 5_8S rRNA is also found in archaea. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00002)
         | 
| 791 791 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000375)
         | 
| 792 792 | 
             
                    """
         | 
| 793 | 
            -
                    return  | 
| 793 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000375')
         | 
| 794 794 |  | 
| 795 795 | 
             
                @classmethod
         | 
| 796 796 | 
             
                def hammerhead_ribozyme(cls):
         | 
| 797 797 | 
             
                    """A small catalytic RNA motif that catalyzes self-cleavage reaction. Its name comes from its secondary structure which resembles a carpenter's hammer. The hammerhead ribozyme is involved in the replication of some viroid and some satellite RNAs. (cls, PMID:2436805)
         | 
| 798 798 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000380)
         | 
| 799 799 | 
             
                    """
         | 
| 800 | 
            -
                    return  | 
| 800 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000380')
         | 
| 801 801 |  | 
| 802 802 | 
             
                @classmethod
         | 
| 803 803 | 
             
                def RNase_MRP_RNA(cls):
         | 
| 804 804 | 
             
                    """The RNA molecule essential for the catalytic activity of RNase MRP, an enzymatically active ribonucleoprotein with two distinct roles in eukaryotes. In mitochondria it plays a direct role in the initiation of mitochondrial DNA replication. In the nucleus it is involved in precursor rRNA processing, where it cleaves the internal transcribed spacer 1 between 18S and 5.8S rRNAs. (cls, http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00030)
         | 
| 805 805 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000385)
         | 
| 806 806 | 
             
                    """
         | 
| 807 | 
            -
                    return  | 
| 807 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000385')
         | 
| 808 808 |  | 
| 809 809 | 
             
                @classmethod
         | 
| 810 810 | 
             
                def RNase_P_RNA(cls):
         | 
| 811 811 | 
             
                    """The RNA component of Ribonuclease P (cls, RNase P), a ubiquitous endoribonuclease, found in archaea, bacteria and eukarya as well as chloroplasts and mitochondria. Its best characterized activity is the generation of mature 5 prime ends of tRNAs by cleaving the 5 prime leader elements of precursor-tRNAs. Cellular RNase Ps are ribonucleoproteins. RNA from bacterial RNase Ps retains its catalytic activity in the absence of the protein subunit, i.e. it is a ribozyme. Isolated eukaryotic and archaeal RNase P RNA has not been shown to retain its catalytic function, but is still essential for the catalytic activity of the holoenzyme. Although the archaeal and eukaryotic holoenzymes have a much greater protein content than the bacterial ones, the RNA cores from all the three lineages are homologous. Helices corresponding to P1, P2, P3, P4, and P10/11 are common to all cellular RNase P RNAs. Yet, there is considerable sequence variation, particularly among the eukaryotic RNAs. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00010)
         | 
| 812 812 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000386)
         | 
| 813 813 | 
             
                    """
         | 
| 814 | 
            -
                    return  | 
| 814 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000386')
         | 
| 815 815 |  | 
| 816 816 | 
             
                @classmethod
         | 
| 817 817 | 
             
                def telomerase_RNA(cls):
         | 
| 818 818 | 
             
                    """The RNA component of telomerase, a reverse transcriptase that synthesizes telomeric DNA. (cls, http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00025)
         | 
| 819 819 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000390)
         | 
| 820 820 | 
             
                    """
         | 
| 821 | 
            -
                    return  | 
| 821 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000390')
         | 
| 822 822 |  | 
| 823 823 | 
             
                @classmethod
         | 
| 824 824 | 
             
                def U1_snRNA(cls):
         | 
| 825 825 | 
             
                    """U1 is a small nuclear RNA (cls, snRNA) component of the spliceosome (involved in pre-mRNA splicing). Its 5' end forms complementary base pairs with the 5' splice junction, thus defining the 5' donor site of an intron. There are significant differences in sequence and secondary structure between metazoan and yeast U1 snRNAs, the latter being much longer (568 nucleotides as compared to 164 nucleotides in human). Nevertheless, secondary structure predictions suggest that all U1 snRNAs share a 'common core' consisting of helices I, II, the proximal region of III, and IV. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00003)
         | 
| 826 826 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000391)
         | 
| 827 827 | 
             
                    """
         | 
| 828 | 
            -
                    return  | 
| 828 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000391')
         | 
| 829 829 |  | 
| 830 830 | 
             
                @classmethod
         | 
| 831 831 | 
             
                def U2_snRNA(cls):
         | 
| 832 832 | 
             
                    """U2 is a small nuclear RNA (cls, snRNA) component of the spliceosome (involved in pre-mRNA splicing). Complementary binding between U2 snRNA (in an area lying towards the 5' end but 3' to hairpin I) and the branchpoint sequence (BPS) of the intron results in the bulging out of an unpaired adenine, on the BPS, which initiates a nucleophilic attack at the intronic 5' splice site, thus starting the first of two transesterification reactions that mediate splicing. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00004)
         | 
| 833 833 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000392)
         | 
| 834 834 | 
             
                    """
         | 
| 835 | 
            -
                    return  | 
| 835 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000392')
         | 
| 836 836 |  | 
| 837 837 | 
             
                @classmethod
         | 
| 838 838 | 
             
                def U4_snRNA(cls):
         | 
| 839 839 | 
             
                    """U4 small nuclear RNA (cls, U4 snRNA) is a component of the major U2-dependent spliceosome. It forms a duplex with U6, and with each splicing round, it is displaced from U6 (and the spliceosome) in an ATP-dependent manner, allowing U6 to refold and create the active site for splicing catalysis. A recycling process involving protein Prp24 re-anneals U4 and U6. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00015)
         | 
| 840 840 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000393)
         | 
| 841 841 | 
             
                    """
         | 
| 842 | 
            -
                    return  | 
| 842 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000393')
         | 
| 843 843 |  | 
| 844 844 | 
             
                @classmethod
         | 
| 845 845 | 
             
                def U4atac_snRNA(cls):
         | 
| 846 846 | 
             
                    """An snRNA required for the splicing of the minor U12-dependent class of eukaryotic nuclear introns. It forms a base paired complex with U6atac_snRNA (cls, SO:0000397). (PMID:=12409455)
         | 
| 847 847 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000394)
         | 
| 848 848 | 
             
                    """
         | 
| 849 | 
            -
                    return  | 
| 849 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000394')
         | 
| 850 850 |  | 
| 851 851 | 
             
                @classmethod
         | 
| 852 852 | 
             
                def U5_snRNA(cls):
         | 
| 853 853 | 
             
                    """U5 RNA is a component of both types of known spliceosome. The precise function of this molecule is unknown, though it is known that the 5' loop is required for splice site selection and p220 binding, and that both the 3' stem-loop and the Sm site are important for Sm protein binding and cap methylation. (cls, http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00020)
         | 
| 854 854 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000395)
         | 
| 855 855 | 
             
                    """
         | 
| 856 | 
            -
                    return  | 
| 856 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000395')
         | 
| 857 857 |  | 
| 858 858 | 
             
                @classmethod
         | 
| 859 859 | 
             
                def U6_snRNA(cls):
         | 
| 860 860 | 
             
                    """U6 snRNA is a component of the spliceosome which is involved in splicing pre-mRNA. The putative secondary structure consensus base pairing is confined to a short 5' stem loop, but U6 snRNA is thought to form extensive base-pair interactions with U4 snRNA. (cls, http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00015)
         | 
| 861 861 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000396)
         | 
| 862 862 | 
             
                    """
         | 
| 863 | 
            -
                    return  | 
| 863 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000396')
         | 
| 864 864 |  | 
| 865 865 | 
             
                @classmethod
         | 
| 866 866 | 
             
                def U6atac_snRNA(cls):
         | 
| 867 867 | 
             
                    """U6atac_snRNA is an snRNA required for the splicing of the minor U12-dependent class of eukaryotic nuclear introns. It forms a base paired complex with U4atac_snRNA (cls, SO:0000394). (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=retrieve&db=pubmed&list_uids=12409455&dopt=Abstract)
         | 
| 868 868 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000397)
         | 
| 869 869 | 
             
                    """
         | 
| 870 | 
            -
                    return  | 
| 870 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000397')
         | 
| 871 871 |  | 
| 872 872 | 
             
                @classmethod
         | 
| 873 873 | 
             
                def U11_snRNA(cls):
         | 
| 874 874 | 
             
                    """U11 snRNA plays a role in splicing of the minor U12-dependent class of eukaryotic nuclear introns, similar to U1 snRNA in the major class spliceosome it base pairs to the conserved 5' splice site sequence. (cls, PMID:9622129)
         | 
| 875 875 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000398)
         | 
| 876 876 | 
             
                    """
         | 
| 877 | 
            -
                    return  | 
| 877 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000398')
         | 
| 878 878 |  | 
| 879 879 | 
             
                @classmethod
         | 
| 880 880 | 
             
                def U12_snRNA(cls):
         | 
| 881 881 | 
             
                    """The U12 small nuclear (cls, snRNA), together with U4atac/U6atac, U5, and U11 snRNAs and associated proteins, forms a spliceosome that cleaves a divergent class of low-abundance pre-mRNA introns. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00007)
         | 
| 882 882 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000399)
         | 
| 883 883 | 
             
                    """
         | 
| 884 | 
            -
                    return  | 
| 884 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000399')
         | 
| 885 885 |  | 
| 886 886 | 
             
                @classmethod
         | 
| 887 887 | 
             
                def U14_snoRNA(cls):
         | 
| 888 888 | 
             
                    """U14 small nucleolar RNA (cls, U14 snoRNA) is required for early cleavages of eukaryotic precursor rRNAs. In yeasts, this molecule possess a stem-loop region (known as the Y-domain) which is essential for function. A similar structure, but with a different consensus sequence, is found in plants, but is absent in vertebrates. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00016, PMID:2551119)
         | 
| 889 889 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000403)
         | 
| 890 890 | 
             
                    """
         | 
| 891 | 
            -
                    return  | 
| 891 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000403')
         | 
| 892 892 |  | 
| 893 893 | 
             
                @classmethod
         | 
| 894 894 | 
             
                def vault_RNA(cls):
         | 
| 895 895 | 
             
                    """A family of RNAs are found as part of the enigmatic vault ribonucleoprotein complex. The complex consists of a major vault protein (cls, MVP), two minor vault proteins (VPARP and TEP1), and several small untranslated RNA molecules. It has been suggested that the vault complex is involved in drug resistance. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00006)
         | 
| 896 896 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000404)
         | 
| 897 897 | 
             
                    """
         | 
| 898 | 
            -
                    return  | 
| 898 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000404')
         | 
| 899 899 |  | 
| 900 900 | 
             
                @classmethod
         | 
| 901 901 | 
             
                def Y_RNA(cls):
         | 
| 902 902 | 
             
                    """Y RNAs are components of the Ro ribonucleoprotein particle (cls, Ro RNP), in association with Ro60 and La proteins. The Y RNAs and Ro60 and La proteins are well conserved, but the function of the Ro RNP is not known. In humans the RNA component can be one of four small RNAs: hY1, hY3, hY4 and hY5. These small RNAs are predicted to fold into a conserved secondary structure containing three stem structures. The largest of the four, hY1, contains an additional hairpin. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00019)
         | 
| 903 903 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000405)
         | 
| 904 904 | 
             
                    """
         | 
| 905 | 
            -
                    return  | 
| 905 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000405')
         | 
| 906 906 |  | 
| 907 907 | 
             
                @classmethod
         | 
| 908 908 | 
             
                def rRNA_18S(cls):
         | 
| 909 909 | 
             
                    """A large polynucleotide in eukaryotes, which functions as the small subunit of the ribosome. (cls, SO:ke)
         | 
| 910 910 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000407)
         | 
| 911 911 | 
             
                    """
         | 
| 912 | 
            -
                    return  | 
| 912 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000407')
         | 
| 913 913 |  | 
| 914 914 | 
             
                @classmethod
         | 
| 915 915 | 
             
                def binding_site(cls):
         | 
| 916 916 | 
             
                    """A biological_region of sequence that, in the molecule, interacts selectively and non-covalently with other molecules. A region on the surface of a molecule that may interact with another molecule. When applied to polypeptides: Amino acids involved in binding or interactions. It can also apply to an amino acid bond which is represented by the positions of the two flanking amino acids. (cls, EBIBS:GAR, SO:ke)
         | 
| 917 917 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000409)
         | 
| 918 918 | 
             
                    """
         | 
| 919 | 
            -
                    return  | 
| 919 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000409')
         | 
| 920 920 |  | 
| 921 921 | 
             
                @classmethod
         | 
| 922 922 | 
             
                def protein_binding_site(cls):
         | 
| 923 923 | 
             
                    """A binding site that, in the molecule, interacts selectively and non-covalently with polypeptide molecules. (cls, SO:ke)
         | 
| 924 924 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000410)
         | 
| 925 925 | 
             
                    """
         | 
| 926 | 
            -
                    return  | 
| 926 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000410')
         | 
| 927 927 |  | 
| 928 928 | 
             
                @classmethod
         | 
| 929 929 | 
             
                def restriction_fragment(cls):
         | 
| 930 930 | 
             
                    """A region of polynucleotide sequence produced by digestion with a restriction endonuclease. (cls, SO:ke)
         | 
| 931 931 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000412)
         | 
| 932 932 | 
             
                    """
         | 
| 933 | 
            -
                    return  | 
| 933 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000412')
         | 
| 934 934 |  | 
| 935 935 | 
             
                @classmethod
         | 
| 936 936 | 
             
                def sequence_difference(cls):
         | 
| 937 937 | 
             
                    """A region where the sequence differs from that of a specified sequence. (cls, SO:ke)
         | 
| 938 938 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000413)
         | 
| 939 939 | 
             
                    """
         | 
| 940 | 
            -
                    return  | 
| 940 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000413')
         | 
| 941 941 |  | 
| 942 942 | 
             
                @classmethod
         | 
| 943 943 | 
             
                def signal_peptide(cls):
         | 
| 944 944 | 
             
                    """The signal_peptide is a short region of the peptide located at the N-terminus that directs the protein to be secreted or part of membrane components. (cls, http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
         | 
| 945 945 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000418)
         | 
| 946 946 | 
             
                    """
         | 
| 947 | 
            -
                    return  | 
| 947 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000418')
         | 
| 948 948 |  | 
| 949 949 | 
             
                @classmethod
         | 
| 950 950 | 
             
                def mature_protein_region(cls):
         | 
| 951 951 | 
             
                    """The polypeptide sequence that remains when the cleaved peptide regions have been cleaved from the immature peptide. (cls, EBIBS:GAR, http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html, SO:cb)
         | 
| 952 952 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000419)
         | 
| 953 953 | 
             
                    """
         | 
| 954 | 
            -
                    return  | 
| 954 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000419')
         | 
| 955 955 |  | 
| 956 956 | 
             
                @classmethod
         | 
| 957 957 | 
             
                def ARS(cls):
         | 
| 958 958 | 
             
                    """A sequence that can autonomously replicate, as a plasmid, when transformed into a bacterial host. (cls, SO:ma)
         | 
| 959 959 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000436)
         | 
| 960 960 | 
             
                    """
         | 
| 961 | 
            -
                    return  | 
| 961 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000436')
         | 
| 962 962 |  | 
| 963 963 | 
             
                @classmethod
         | 
| 964 964 | 
             
                def ss_oligo(cls):
         | 
| 965 965 | 
             
                    """A single stranded oligonucleotide. (cls, SO:ke)
         | 
| 966 966 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000441)
         | 
| 967 967 | 
             
                    """
         | 
| 968 | 
            -
                    return  | 
| 968 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000441')
         | 
| 969 969 |  | 
| 970 970 | 
             
                @classmethod
         | 
| 971 971 | 
             
                def ds_oligo(cls):
         | 
| 972 972 | 
             
                    """A double stranded oligonucleotide. (cls, SO:ke)
         | 
| 973 973 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000442)
         | 
| 974 974 | 
             
                    """
         | 
| 975 | 
            -
                    return  | 
| 975 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000442')
         | 
| 976 976 |  | 
| 977 977 | 
             
                @classmethod
         | 
| 978 978 | 
             
                def rasiRNA(cls):
         | 
| 979 979 | 
             
                    """A 17-28-nt, small interfering RNA derived from transcripts of repetitive elements. (cls, http://www.developmentalcell.com/content/article/abstract?uid=PIIS1534580703002284)
         | 
| 980 980 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000454)
         | 
| 981 981 | 
             
                    """
         | 
| 982 | 
            -
                    return  | 
| 982 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000454')
         | 
| 983 983 |  | 
| 984 984 | 
             
                @classmethod
         | 
| 985 985 | 
             
                def pseudogenic_region(cls):
         | 
| 986 986 | 
             
                    """A non-functional descendent of a functional entity. (cls, SO:cjm)
         | 
| 987 987 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000462)
         | 
| 988 988 | 
             
                    """
         | 
| 989 | 
            -
                    return  | 
| 989 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000462')
         | 
| 990 990 |  | 
| 991 991 | 
             
                @classmethod
         | 
| 992 992 | 
             
                def decayed_exon(cls):
         | 
| 993 993 | 
             
                    """A non-functional descendant of an exon. (cls, SO:ke)
         | 
| 994 994 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000464)
         | 
| 995 995 | 
             
                    """
         | 
| 996 | 
            -
                    return  | 
| 996 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000464')
         | 
| 997 997 |  | 
| 998 998 | 
             
                @classmethod
         | 
| 999 999 | 
             
                def golden_path_fragment(cls):
         | 
| 1000 1000 | 
             
                    """One of the pieces of sequence that make up a golden path. (cls, SO:rd)
         | 
| 1001 1001 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000468)
         | 
| 1002 1002 | 
             
                    """
         | 
| 1003 | 
            -
                    return  | 
| 1003 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000468')
         | 
| 1004 1004 |  | 
| 1005 1005 | 
             
                @classmethod
         | 
| 1006 1006 | 
             
                def tiling_path(cls):
         | 
| 1007 1007 | 
             
                    """A set of regions which overlap with minimal polymorphism to form a linear sequence. (cls, SO:cjm)
         | 
| 1008 1008 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000472)
         | 
| 1009 1009 | 
             
                    """
         | 
| 1010 | 
            -
                    return  | 
| 1010 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000472')
         | 
| 1011 1011 |  | 
| 1012 1012 | 
             
                @classmethod
         | 
| 1013 1013 | 
             
                def tiling_path_fragment(cls):
         | 
| 1014 1014 | 
             
                    """A piece of sequence that makes up a tiling_path (cls, SO:0000472). (SO:ke)
         | 
| 1015 1015 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000474)
         | 
| 1016 1016 | 
             
                    """
         | 
| 1017 | 
            -
                    return  | 
| 1017 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000474')
         | 
| 1018 1018 |  | 
| 1019 1019 | 
             
                @classmethod
         | 
| 1020 1020 | 
             
                def nc_primary_transcript(cls):
         | 
| 1021 1021 | 
             
                    """A primary transcript that is never translated into a protein. (cls, SO:ke)
         | 
| 1022 1022 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000483)
         | 
| 1023 1023 | 
             
                    """
         | 
| 1024 | 
            -
                    return  | 
| 1024 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000483')
         | 
| 1025 1025 |  | 
| 1026 1026 | 
             
                @classmethod
         | 
| 1027 1027 | 
             
                def three_prime_coding_exon_noncoding_region(cls):
         | 
| 1028 1028 | 
             
                    """The sequence of the 3' exon that is not coding. (cls, SO:ke)
         | 
| 1029 1029 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000484)
         | 
| 1030 1030 | 
             
                    """
         | 
| 1031 | 
            -
                    return  | 
| 1031 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000484')
         | 
| 1032 1032 |  | 
| 1033 1033 | 
             
                @classmethod
         | 
| 1034 1034 | 
             
                def five_prime_coding_exon_noncoding_region(cls):
         | 
| 1035 1035 | 
             
                    """The sequence of the 5' exon preceding the start codon. (cls, SO:ke)
         | 
| 1036 1036 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000486)
         | 
| 1037 1037 | 
             
                    """
         | 
| 1038 | 
            -
                    return  | 
| 1038 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000486')
         | 
| 1039 1039 |  | 
| 1040 1040 | 
             
                @classmethod
         | 
| 1041 1041 | 
             
                def virtual_sequence(cls):
         | 
| 1042 1042 | 
             
                    """A continuous piece of sequence similar to the 'virtual contig' concept of the Ensembl database. (cls, SO:ke)
         | 
| 1043 1043 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000499)
         | 
| 1044 1044 | 
             
                    """
         | 
| 1045 | 
            -
                    return  | 
| 1045 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000499')
         | 
| 1046 1046 |  | 
| 1047 1047 | 
             
                @classmethod
         | 
| 1048 1048 | 
             
                def transcribed_region(cls):
         | 
| 1049 1049 | 
             
                    """A region of sequence that is transcribed. This region may cover the transcript of a gene, it may emcompas the sequence covered by all of the transcripts of a alternately spliced gene, or it may cover the region transcribed by a polycistronic transcript. A gene may have 1 or more transcribed regions and a transcribed_region may belong to one or more genes. (cls, SO:ke)
         | 
| 1050 1050 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000502)
         | 
| 1051 1051 | 
             
                    """
         | 
| 1052 | 
            -
                    return  | 
| 1052 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000502')
         | 
| 1053 1053 |  | 
| 1054 1054 | 
             
                @classmethod
         | 
| 1055 1055 | 
             
                def polyA_signal_sequence(cls):
         | 
| 1056 1056 | 
             
                    """The recognition sequence necessary for endonuclease cleavage of an RNA transcript that is followed by polyadenylation; consensus=AATAAA. (cls, http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
         | 
| 1057 1057 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000551)
         | 
| 1058 1058 | 
             
                    """
         | 
| 1059 | 
            -
                    return  | 
| 1059 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000551')
         | 
| 1060 1060 |  | 
| 1061 1061 | 
             
                @classmethod
         | 
| 1062 1062 | 
             
                def polyA_site(cls):
         | 
| 1063 1063 | 
             
                    """The site on an RNA transcript to which will be added adenine residues by post-transcriptional polyadenylation. The boundary between the UTR and the polyA sequence. (cls, http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
         | 
| 1064 1064 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000553)
         | 
| 1065 1065 | 
             
                    """
         | 
| 1066 | 
            -
                    return  | 
| 1066 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000553')
         | 
| 1067 1067 |  | 
| 1068 1068 | 
             
                @classmethod
         | 
| 1069 1069 | 
             
                def centromere(cls):
         | 
| 1070 1070 | 
             
                    """A region of chromosome where the spindle fibers attach during mitosis and meiosis. (cls, SO:ke)
         | 
| 1071 1071 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000577)
         | 
| 1072 1072 | 
             
                    """
         | 
| 1073 | 
            -
                    return  | 
| 1073 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000577')
         | 
| 1074 1074 |  | 
| 1075 1075 | 
             
                @classmethod
         | 
| 1076 1076 | 
             
                def cap(cls):
         | 
| 1077 1077 | 
             
                    """A structure consisting of a 7-methylguanosine in 5'-5' triphosphate linkage with the first nucleotide of an mRNA. It is added post-transcriptionally, and is not encoded in the DNA. (cls, http://seqcore.brcf.med.umich.edu/doc/educ/dnapr/mbglossary/mbgloss.html)
         | 
| 1078 1078 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000581)
         | 
| 1079 1079 | 
             
                    """
         | 
| 1080 | 
            -
                    return  | 
| 1080 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000581')
         | 
| 1081 1081 |  | 
| 1082 1082 | 
             
                @classmethod
         | 
| 1083 1083 | 
             
                def group_I_intron(cls):
         | 
| 1084 1084 | 
             
                    """Group I catalytic introns are large self-splicing ribozymes. They catalyze their own excision from mRNA, tRNA and rRNA precursors in a wide range of organisms. The core secondary structure consists of 9 paired regions (cls, P1-P9). These fold to essentially two domains, the P4-P6 domain (formed from the stacking of P5, P4, P6 and P6a helices) and the P3-P9 domain (formed from the P8, P3, P7 and P9 helices). Group I catalytic introns often have long ORFs inserted in loop regions. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00028)
         | 
| 1085 1085 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000587)
         | 
| 1086 1086 | 
             
                    """
         | 
| 1087 | 
            -
                    return  | 
| 1087 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000587')
         | 
| 1088 1088 |  | 
| 1089 1089 | 
             
                @classmethod
         | 
| 1090 1090 | 
             
                def autocatalytically_spliced_intron(cls):
         | 
| 1091 1091 | 
             
                    """A self spliced intron. (cls, SO:ke)
         | 
| 1092 1092 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000588)
         | 
| 1093 1093 | 
             
                    """
         | 
| 1094 | 
            -
                    return  | 
| 1094 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000588')
         | 
| 1095 1095 |  | 
| 1096 1096 | 
             
                @classmethod
         | 
| 1097 1097 | 
             
                def SRP_RNA(cls):
         | 
| 1098 1098 | 
             
                    """The signal recognition particle (cls, SRP) is a universally conserved ribonucleoprotein. It is involved in the co-translational targeting of proteins to membranes. The eukaryotic SRP consists of a 300-nucleotide 7S RNA and six proteins: SRPs 72, 68, 54, 19, 14, and 9. Archaeal SRP consists of a 7S RNA and homologues of the eukaryotic SRP19 and SRP54 proteins. In most eubacteria, the SRP consists of a 4.5S RNA and the Ffh protein (a homologue of the eukaryotic SRP54 protein). Eukaryotic and archaeal 7S RNAs have very similar secondary structures, with eight helical elements. These fold into the Alu and S domains, separated by a long linker region. Eubacterial SRP is generally a simpler structure, with the M domain of Ffh bound to a region of the 4.5S RNA that corresponds to helix 8 of the eukaryotic and archaeal SRP S domain. Some Gram-positive bacteria (e.g. Bacillus subtilis), however, have a larger SRP RNA that also has an Alu domain. The Alu domain is thought to mediate the peptide chain elongation retardation function of the SRP. The universally conserved helix which interacts with the SRP54/Ffh M domain mediates signal sequence recognition. In eukaryotes and archaea, the SRP19-helix 6 complex is thought to be involved in SRP assembly and stabilizes helix 8 for SRP54 binding. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00017)
         | 
| 1099 1099 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000590)
         | 
| 1100 1100 | 
             
                    """
         | 
| 1101 | 
            -
                    return  | 
| 1101 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000590')
         | 
| 1102 1102 |  | 
| 1103 1103 | 
             
                @classmethod
         | 
| 1104 1104 | 
             
                def C_D_box_snoRNA(cls):
         | 
| 1105 1105 | 
             
                    """Most box C/D snoRNAs also contain long (cls, >10 nt) sequences complementary to rRNA. Boxes C and D, as well as boxes C' and D', are usually located in close proximity, and form a structure known as the box C/D motif. This motif is important for snoRNA stability, processing, nucleolar targeting and function. A small number of box C/D snoRNAs are involved in rRNA processing; most, however, are known or predicted to serve as guide RNAs in ribose methylation of rRNA. Targeting involves direct base pairing of the snoRNA at the rRNA site to be modified and selection of a rRNA nucleotide a fixed distance from box D or D'. (http://www.bio.umass.edu/biochem/rna-sequence/Yeast_snoRNA_Database/snoRNA_DataBase.html)
         | 
| 1106 1106 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000593)
         | 
| 1107 1107 | 
             
                    """
         | 
| 1108 | 
            -
                    return  | 
| 1108 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000593')
         | 
| 1109 1109 |  | 
| 1110 1110 | 
             
                @classmethod
         | 
| 1111 1111 | 
             
                def guide_RNA(cls):
         | 
| 1112 1112 | 
             
                    """A short 3'-uridylated RNA that can form a duplex (cls, except for its post-transcriptionally added oligo_U tail (SO:0000609)) with a stretch of mature edited mRNA. (http://www.rna.ucla.edu/index.html)
         | 
| 1113 1113 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000602)
         | 
| 1114 1114 | 
             
                    """
         | 
| 1115 | 
            -
                    return  | 
| 1115 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000602')
         | 
| 1116 1116 |  | 
| 1117 1117 | 
             
                @classmethod
         | 
| 1118 1118 | 
             
                def group_II_intron(cls):
         | 
| 1119 1119 | 
             
                    """Group II introns are found in rRNA, tRNA and mRNA of organelles in fungi, plants and protists, and also in mRNA in bacteria. They are large self-splicing ribozymes and have 6 structural domains (cls, usually designated dI to dVI). A subset of group II introns also encode essential splicing proteins in intronic ORFs. The length of these introns can therefore be up to 3kb. Splicing occurs in almost identical fashion to nuclear pre-mRNA splicing with two transesterification steps. The 2' hydroxyl of a bulged adenosine in domain VI attacks the 5' splice site, followed by nucleophilic attack on the 3' splice site by the 3' OH of the upstream exon. Protein machinery is required for splicing in vivo, and long range intron-intron and intron-exon interactions are important for splice site positioning. Group II introns are further sub-classified into groups IIA and IIB which differ in splice site consensus, distance of bulged A from 3' splice site, some tertiary interactions, and intronic ORF phylogeny. (http://www.sanger.ac.uk/Software/Rfam/browse/index.shtml)
         | 
| 1120 1120 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000603)
         | 
| 1121 1121 | 
             
                    """
         | 
| 1122 | 
            -
                    return  | 
| 1122 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000603')
         | 
| 1123 1123 |  | 
| 1124 1124 | 
             
                @classmethod
         | 
| 1125 1125 | 
             
                def intergenic_region(cls):
         | 
| 1126 1126 | 
             
                    """A region containing or overlapping no genes that is bounded on either side by a gene, or bounded by a gene and the end of the chromosome. (cls, SO:cjm)
         | 
| 1127 1127 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000605)
         | 
| 1128 1128 | 
             
                    """
         | 
| 1129 | 
            -
                    return  | 
| 1129 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000605')
         | 
| 1130 1130 |  | 
| 1131 1131 | 
             
                @classmethod
         | 
| 1132 1132 | 
             
                def polyA_sequence(cls):
         | 
| 1133 1133 | 
             
                    """Sequence of about 100 nucleotides of A added to the 3' end of most eukaryotic mRNAs. (cls, SO:ke)
         | 
| 1134 1134 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000610)
         | 
| 1135 1135 | 
             
                    """
         | 
| 1136 | 
            -
                    return  | 
| 1136 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000610')
         | 
| 1137 1137 |  | 
| 1138 1138 | 
             
                @classmethod
         | 
| 1139 1139 | 
             
                def branch_site(cls):
         | 
| 1140 1140 | 
             
                    """A pyrimidine rich sequence near the 3' end of an intron to which the 5'end becomes covalently bound during nuclear splicing. The resulting structure resembles a lariat. (cls, SO:ke)
         | 
| 1141 1141 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000611)
         | 
| 1142 1142 | 
             
                    """
         | 
| 1143 | 
            -
                    return  | 
| 1143 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000611')
         | 
| 1144 1144 |  | 
| 1145 1145 | 
             
                @classmethod
         | 
| 1146 1146 | 
             
                def polypyrimidine_tract(cls):
         | 
| 1147 1147 | 
             
                    """The polypyrimidine tract is one of the cis-acting sequence elements directing intron removal in pre-mRNA splicing. (cls, http://nar.oupjournals.org/cgi/content/full/25/4/888)
         | 
| 1148 1148 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000612)
         | 
| 1149 1149 | 
             
                    """
         | 
| 1150 | 
            -
                    return  | 
| 1150 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000612')
         | 
| 1151 1151 |  | 
| 1152 1152 | 
             
                @classmethod
         | 
| 1153 1153 | 
             
                def transcription_end_site(cls):
         | 
| 1154 1154 | 
             
                    """The base where transcription ends. (cls, SO:ke)
         | 
| 1155 1155 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000616)
         | 
| 1156 1156 | 
             
                    """
         | 
| 1157 | 
            -
                    return  | 
| 1157 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000616')
         | 
| 1158 1158 |  | 
| 1159 1159 | 
             
                @classmethod
         | 
| 1160 1160 | 
             
                def telomere(cls):
         | 
| 1161 1161 | 
             
                    """A specific structure at the end of a linear chromosome, required for the integrity and maintenance of the end. (cls, SO:ma)
         | 
| 1162 1162 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000624)
         | 
| 1163 1163 | 
             
                    """
         | 
| 1164 | 
            -
                    return  | 
| 1164 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000624')
         | 
| 1165 1165 |  | 
| 1166 1166 | 
             
                @classmethod
         | 
| 1167 1167 | 
             
                def silencer(cls):
         | 
| 1168 1168 | 
             
                    """A regulatory region which upon binding of transcription factors, suppress the transcription of the gene or genes they control. (cls, SO:ke)
         | 
| 1169 1169 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000625)
         | 
| 1170 1170 | 
             
                    """
         | 
| 1171 | 
            -
                    return  | 
| 1171 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000625')
         | 
| 1172 1172 |  | 
| 1173 1173 | 
             
                @classmethod
         | 
| 1174 1174 | 
             
                def insulator(cls):
         | 
| 1175 1175 | 
             
                    """A transcriptional cis regulatory region that when located between a CM and a gene's promoter prevents the CRM from modulating that genes expression. (cls, SO:regcreative)
         | 
| 1176 1176 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000627)
         | 
| 1177 1177 | 
             
                    """
         | 
| 1178 | 
            -
                    return  | 
| 1178 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000627')
         | 
| 1179 1179 |  | 
| 1180 1180 | 
             
                @classmethod
         | 
| 1181 1181 | 
             
                def chromosomal_structural_element(cls):
         | 
| 1182 | 
            -
                    return  | 
| 1182 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000628')
         | 
| 1183 1183 |  | 
| 1184 1184 | 
             
                @classmethod
         | 
| 1185 1185 | 
             
                def minisatellite(cls):
         | 
| 1186 1186 | 
             
                    """A repeat region containing tandemly repeated sequences having a unit length of 10 to 40 bp. (cls, http://www.informatics.jax.org/silver/glossary.shtml)
         | 
| 1187 1187 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000643)
         | 
| 1188 1188 | 
             
                    """
         | 
| 1189 | 
            -
                    return  | 
| 1189 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000643')
         | 
| 1190 1190 |  | 
| 1191 1191 | 
             
                @classmethod
         | 
| 1192 1192 | 
             
                def antisense_RNA(cls):
         | 
| 1193 1193 | 
             
                    """Antisense RNA is RNA that is transcribed from the coding, rather than the template, strand of DNA. It is therefore complementary to mRNA. (cls, SO:ke)
         | 
| 1194 1194 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000644)
         | 
| 1195 1195 | 
             
                    """
         | 
| 1196 | 
            -
                    return  | 
| 1196 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000644')
         | 
| 1197 1197 |  | 
| 1198 1198 | 
             
                @classmethod
         | 
| 1199 1199 | 
             
                def antisense_primary_transcript(cls):
         | 
| 1200 1200 | 
             
                    """The reverse complement of the primary transcript. (cls, SO:ke)
         | 
| 1201 1201 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000645)
         | 
| 1202 1202 | 
             
                    """
         | 
| 1203 | 
            -
                    return  | 
| 1203 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000645')
         | 
| 1204 1204 |  | 
| 1205 1205 | 
             
                @classmethod
         | 
| 1206 1206 | 
             
                def siRNA(cls):
         | 
| 1207 1207 | 
             
                    """A small RNA molecule that is the product of a longer exogenous or endogenous dsRNA, which is either a bimolecular duplex or very long hairpin, processed (cls, via the Dicer pathway) such that numerous siRNAs accumulate from both strands of the dsRNA. SRNAs trigger the cleavage of their target molecules. (PMID:12592000)
         | 
| 1208 1208 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000646)
         | 
| 1209 1209 | 
             
                    """
         | 
| 1210 | 
            -
                    return  | 
| 1210 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000646')
         | 
| 1211 1211 |  | 
| 1212 1212 | 
             
                @classmethod
         | 
| 1213 1213 | 
             
                def stRNA(cls):
         | 
| 1214 1214 | 
             
                    """Non-coding RNAs of about 21 nucleotides in length that regulate temporal development; first discovered in C. elegans. (cls, PMID:11081512)
         | 
| 1215 1215 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000649)
         | 
| 1216 1216 | 
             
                    """
         | 
| 1217 | 
            -
                    return  | 
| 1217 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000649')
         | 
| 1218 1218 |  | 
| 1219 1219 | 
             
                @classmethod
         | 
| 1220 1220 | 
             
                def small_subunit_rRNA(cls):
         | 
| 1221 1221 | 
             
                    """Ribosomal RNA transcript that structures the small subunit of the ribosome. (cls, SO:ke)
         | 
| 1222 1222 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000650)
         | 
| 1223 1223 | 
             
                    """
         | 
| 1224 | 
            -
                    return  | 
| 1224 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000650')
         | 
| 1225 1225 |  | 
| 1226 1226 | 
             
                @classmethod
         | 
| 1227 1227 | 
             
                def large_subunit_rRNA(cls):
         | 
| 1228 1228 | 
             
                    """Ribosomal RNA transcript that structures the large subunit of the ribosome. (cls, SO:ke)
         | 
| 1229 1229 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000651)
         | 
| 1230 1230 | 
             
                    """
         | 
| 1231 | 
            -
                    return  | 
| 1231 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000651')
         | 
| 1232 1232 |  | 
| 1233 1233 | 
             
                @classmethod
         | 
| 1234 1234 | 
             
                def rRNA_5S(cls):
         | 
| 1235 1235 | 
             
                    """5S ribosomal RNA (cls, 5S rRNA) is a component of the large ribosomal subunit in both prokaryotes and eukaryotes. In eukaryotes, it is synthesised by RNA polymerase III (the other eukaryotic rRNAs are cleaved from a 45S precursor synthesised by RNA polymerase I). In Xenopus oocytes, it has been shown that fingers 4-7 of the nine-zinc finger transcription factor TFIIIA can bind to the central region of 5S RNA. Thus, in addition to positively regulating 5S rRNA transcription, TFIIIA also stabilizes 5S rRNA until it is required for transcription. (http://www.sanger.ac.uk/cgi-bin/Rfam/getacc?RF00001)
         | 
| 1236 1236 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000652)
         | 
| 1237 1237 | 
             
                    """
         | 
| 1238 | 
            -
                    return  | 
| 1238 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000652')
         | 
| 1239 1239 |  | 
| 1240 1240 | 
             
                @classmethod
         | 
| 1241 1241 | 
             
                def rRNA_28S(cls):
         | 
| 1242 1242 | 
             
                    """A component of the large ribosomal subunit. (cls, SO:ke)
         | 
| 1243 1243 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000653)
         | 
| 1244 1244 | 
             
                    """
         | 
| 1245 | 
            -
                    return  | 
| 1245 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000653')
         | 
| 1246 1246 |  | 
| 1247 1247 | 
             
                @classmethod
         | 
| 1248 1248 | 
             
                def ncRNA(cls):
         | 
| 1249 1249 | 
             
                    """An RNA transcript that does not encode for a protein rather the RNA molecule is the gene product. (cls, SO:ke)
         | 
| 1250 1250 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000655)
         | 
| 1251 1251 | 
             
                    """
         | 
| 1252 | 
            -
                    return  | 
| 1252 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000655')
         | 
| 1253 1253 |  | 
| 1254 1254 | 
             
                @classmethod
         | 
| 1255 1255 | 
             
                def repeat_region(cls):
         | 
| 1256 1256 | 
             
                    """A region of sequence containing one or more repeat units. (cls, SO:ke)
         | 
| 1257 1257 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000657)
         | 
| 1258 1258 | 
             
                    """
         | 
| 1259 | 
            -
                    return  | 
| 1259 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000657')
         | 
| 1260 1260 |  | 
| 1261 1261 | 
             
                @classmethod
         | 
| 1262 1262 | 
             
                def dispersed_repeat(cls):
         | 
| 1263 1263 | 
             
                    """A repeat that is located at dispersed sites in the genome. (cls, SO:ke)
         | 
| 1264 1264 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000658)
         | 
| 1265 1265 | 
             
                    """
         | 
| 1266 | 
            -
                    return  | 
| 1266 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000658')
         | 
| 1267 1267 |  | 
| 1268 1268 | 
             
                @classmethod
         | 
| 1269 1269 | 
             
                def spliceosomal_intron(cls):
         | 
| 1270 1270 | 
             
                    """An intron which is spliced by the spliceosome. (cls, SO:ke)
         | 
| 1271 1271 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000662)
         | 
| 1272 1272 | 
             
                    """
         | 
| 1273 | 
            -
                    return  | 
| 1273 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000662')
         | 
| 1274 1274 |  | 
| 1275 1275 | 
             
                @classmethod
         | 
| 1276 1276 | 
             
                def insertion(cls):
         | 
| 1277 1277 | 
             
                    """The sequence of one or more nucleotides added between two adjacent nucleotides in the sequence. (cls, SO:ke)
         | 
| 1278 1278 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000667)
         | 
| 1279 1279 | 
             
                    """
         | 
| 1280 | 
            -
                    return  | 
| 1280 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000667')
         | 
| 1281 1281 |  | 
| 1282 1282 | 
             
                @classmethod
         | 
| 1283 1283 | 
             
                def EST_match(cls):
         | 
| 1284 1284 | 
             
                    """A match against an EST sequence. (cls, SO:ke)
         | 
| 1285 1285 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000668)
         | 
| 1286 1286 | 
             
                    """
         | 
| 1287 | 
            -
                    return  | 
| 1287 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000668')
         | 
| 1288 1288 |  | 
| 1289 1289 | 
             
                @classmethod
         | 
| 1290 1290 | 
             
                def transcript(cls):
         | 
| 1291 1291 | 
             
                    """An RNA synthesized on a DNA or RNA template by an RNA polymerase. (cls, SO:ma)
         | 
| 1292 1292 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000673)
         | 
| 1293 1293 | 
             
                    """
         | 
| 1294 | 
            -
                    return  | 
| 1294 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000673')
         | 
| 1295 1295 |  | 
| 1296 1296 | 
             
                @classmethod
         | 
| 1297 1297 | 
             
                def nuclease_sensitive_site(cls):
         | 
| 1298 1298 | 
             
                    """A region of nucleotide sequence targeted by a nuclease enzyme. (cls, SO:ma)
         | 
| 1299 1299 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000684)
         | 
| 1300 1300 | 
             
                    """
         | 
| 1301 | 
            -
                    return  | 
| 1301 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000684')
         | 
| 1302 1302 |  | 
| 1303 1303 | 
             
                @classmethod
         | 
| 1304 1304 | 
             
                def deletion_junction(cls):
         | 
| 1305 1305 | 
             
                    """The space between two bases in a sequence which marks the position where a deletion has occurred. (cls, SO:ke)
         | 
| 1306 1306 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000687)
         | 
| 1307 1307 | 
             
                    """
         | 
| 1308 | 
            -
                    return  | 
| 1308 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000687')
         | 
| 1309 1309 |  | 
| 1310 1310 | 
             
                @classmethod
         | 
| 1311 1311 | 
             
                def golden_path(cls):
         | 
| 1312 1312 | 
             
                    """A set of subregions selected from sequence contigs which when concatenated form a nonredundant linear sequence. (cls, SO:ls)
         | 
| 1313 1313 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000688)
         | 
| 1314 1314 | 
             
                    """
         | 
| 1315 | 
            -
                    return  | 
| 1315 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000688')
         | 
| 1316 1316 |  | 
| 1317 1317 | 
             
                @classmethod
         | 
| 1318 1318 | 
             
                def cDNA_match(cls):
         | 
| 1319 1319 | 
             
                    """A match against cDNA sequence. (cls, SO:ke)
         | 
| 1320 1320 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000689)
         | 
| 1321 1321 | 
             
                    """
         | 
| 1322 | 
            -
                    return  | 
| 1322 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000689')
         | 
| 1323 1323 |  | 
| 1324 1324 | 
             
                @classmethod
         | 
| 1325 1325 | 
             
                def SNP(cls):
         | 
| 1326 1326 | 
             
                    """SNPs are single base pair positions in genomic DNA at which different sequence alternatives exist in normal individuals in some population(cls, s), wherein the least frequent variant has an abundance of 1% or greater. (SO:cb)
         | 
| 1327 1327 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000694)
         | 
| 1328 1328 | 
             
                    """
         | 
| 1329 | 
            -
                    return  | 
| 1329 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000694')
         | 
| 1330 1330 |  | 
| 1331 1331 | 
             
                @classmethod
         | 
| 1332 1332 | 
             
                def reagent(cls):
         | 
| 1333 1333 | 
             
                    """A sequence used in experiment. (cls, SO:ke)
         | 
| 1334 1334 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000695)
         | 
| 1335 1335 | 
             
                    """
         | 
| 1336 | 
            -
                    return  | 
| 1336 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000695')
         | 
| 1337 1337 |  | 
| 1338 1338 | 
             
                @classmethod
         | 
| 1339 1339 | 
             
                def oligo(cls):
         | 
| 1340 1340 | 
             
                    """A short oligonucleotide sequence, of length on the order of 10's of bases; either single or double stranded. (cls, SO:ma)
         | 
| 1341 1341 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000696)
         | 
| 1342 1342 | 
             
                    """
         | 
| 1343 | 
            -
                    return  | 
| 1343 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000696')
         | 
| 1344 1344 |  | 
| 1345 1345 | 
             
                @classmethod
         | 
| 1346 1346 | 
             
                def junction(cls):
         | 
| 1347 1347 | 
             
                    """A sequence_feature with an extent of zero. (cls, SO:ke)
         | 
| 1348 1348 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000699)
         | 
| 1349 1349 | 
             
                    """
         | 
| 1350 | 
            -
                    return  | 
| 1350 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000699')
         | 
| 1351 1351 |  | 
| 1352 1352 | 
             
                @classmethod
         | 
| 1353 1353 | 
             
                def remark(cls):
         | 
| 1354 1354 | 
             
                    """A comment about the sequence. (cls, SO:ke)
         | 
| 1355 1355 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000700)
         | 
| 1356 1356 | 
             
                    """
         | 
| 1357 | 
            -
                    return  | 
| 1357 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000700')
         | 
| 1358 1358 |  | 
| 1359 1359 | 
             
                @classmethod
         | 
| 1360 1360 | 
             
                def possible_base_call_error(cls):
         | 
| 1361 1361 | 
             
                    """A region of sequence where the validity of the base calling is questionable. (cls, SO:ke)
         | 
| 1362 1362 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000701)
         | 
| 1363 1363 | 
             
                    """
         | 
| 1364 | 
            -
                    return  | 
| 1364 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000701')
         | 
| 1365 1365 |  | 
| 1366 1366 | 
             
                @classmethod
         | 
| 1367 1367 | 
             
                def possible_assembly_error(cls):
         | 
| 1368 1368 | 
             
                    """A region of sequence where there may have been an error in the assembly. (cls, SO:ke)
         | 
| 1369 1369 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000702)
         | 
| 1370 1370 | 
             
                    """
         | 
| 1371 | 
            -
                    return  | 
| 1371 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000702')
         | 
| 1372 1372 |  | 
| 1373 1373 | 
             
                @classmethod
         | 
| 1374 1374 | 
             
                def experimental_result_region(cls):
         | 
| 1375 1375 | 
             
                    """A region of sequence implicated in an experimental result. (cls, SO:ke)
         | 
| 1376 1376 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000703)
         | 
| 1377 1377 | 
             
                    """
         | 
| 1378 | 
            -
                    return  | 
| 1378 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000703')
         | 
| 1379 1379 |  | 
| 1380 1380 | 
             
                @classmethod
         | 
| 1381 1381 | 
             
                def gene(cls):
         | 
| 1382 1382 | 
             
                    """A region (cls, or regions) that includes all of the sequence elements necessary to encode a functional transcript. A gene may include regulatory regions, transcribed regions and/or other functional sequence regions. (SO:immuno_workshop)
         | 
| 1383 1383 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000704)
         | 
| 1384 1384 | 
             
                    """
         | 
| 1385 | 
            -
                    return  | 
| 1385 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000704')
         | 
| 1386 1386 |  | 
| 1387 1387 | 
             
                @classmethod
         | 
| 1388 1388 | 
             
                def tandem_repeat(cls):
         | 
| 1389 1389 | 
             
                    """Two or more adjcent copies of a region (cls, of length greater than 1). (SO:ke)
         | 
| 1390 1390 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000705)
         | 
| 1391 1391 | 
             
                    """
         | 
| 1392 | 
            -
                    return  | 
| 1392 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000705')
         | 
| 1393 1393 |  | 
| 1394 1394 | 
             
                @classmethod
         | 
| 1395 1395 | 
             
                def trans_splice_acceptor_site(cls):
         | 
| 1396 1396 | 
             
                    """The 3' splice site of the acceptor primary transcript. (cls, SO:ke)
         | 
| 1397 1397 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000706)
         | 
| 1398 1398 | 
             
                    """
         | 
| 1399 | 
            -
                    return  | 
| 1399 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000706')
         | 
| 1400 1400 |  | 
| 1401 1401 | 
             
                @classmethod
         | 
| 1402 1402 | 
             
                def nucleotide_motif(cls):
         | 
| 1403 1403 | 
             
                    """A region of nucleotide sequence corresponding to a known motif. (cls, SO:ke)
         | 
| 1404 1404 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000714)
         | 
| 1405 1405 | 
             
                    """
         | 
| 1406 | 
            -
                    return  | 
| 1406 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000714')
         | 
| 1407 1407 |  | 
| 1408 1408 | 
             
                @classmethod
         | 
| 1409 1409 | 
             
                def RNA_motif(cls):
         | 
| 1410 1410 | 
             
                    """A motif that is active in RNA sequence. (cls, SO:ke)
         | 
| 1411 1411 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000715)
         | 
| 1412 1412 | 
             
                    """
         | 
| 1413 | 
            -
                    return  | 
| 1413 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000715')
         | 
| 1414 1414 |  | 
| 1415 1415 | 
             
                @classmethod
         | 
| 1416 1416 | 
             
                def reading_frame(cls):
         | 
| 1417 1417 | 
             
                    """A nucleic acid sequence that when read as sequential triplets, has the potential of encoding a sequential string of amino acids. It need not contain the start or stop codon. (cls, SGD:rb)
         | 
| 1418 1418 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000717)
         | 
| 1419 1419 | 
             
                    """
         | 
| 1420 | 
            -
                    return  | 
| 1420 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000717')
         | 
| 1421 1421 |  | 
| 1422 1422 | 
             
                @classmethod
         | 
| 1423 1423 | 
             
                def ultracontig(cls):
         | 
| 1424 1424 | 
             
                    """An ordered and oriented set of scaffolds based on somewhat weaker sets of inferential evidence such as one set of mate pair reads together with supporting evidence from ESTs or location of markers from SNP or microsatellite maps, or cytogenetic localization of contained markers. (cls, FB:WG)
         | 
| 1425 1425 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000719)
         | 
| 1426 1426 | 
             
                    """
         | 
| 1427 | 
            -
                    return  | 
| 1427 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000719')
         | 
| 1428 1428 |  | 
| 1429 1429 | 
             
                @classmethod
         | 
| 1430 1430 | 
             
                def oriT(cls):
         | 
| 1431 1431 | 
             
                    """A region of a DNA molecule where transfer is initiated during the process of conjugation or mobilization. (cls, http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
         | 
| 1432 1432 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000724)
         | 
| 1433 1433 | 
             
                    """
         | 
| 1434 | 
            -
                    return  | 
| 1434 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000724')
         | 
| 1435 1435 |  | 
| 1436 1436 | 
             
                @classmethod
         | 
| 1437 1437 | 
             
                def transit_peptide(cls):
         | 
| 1438 1438 | 
             
                    """The transit_peptide is a short region at the N-terminus of the peptide that directs the protein to an organelle (cls, chloroplast, mitochondrion, microbody or cyanelle). (http://www.ebi.ac.uk/embl/Documentation/FT_definitions/feature_table.html)
         | 
| 1439 1439 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000725)
         | 
| 1440 1440 | 
             
                    """
         | 
| 1441 | 
            -
                    return  | 
| 1441 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000725')
         | 
| 1442 1442 |  | 
| 1443 1443 | 
             
                @classmethod
         | 
| 1444 1444 | 
             
                def CRM(cls):
         | 
| 1445 1445 | 
             
                    """A regulatory_region where more than 1 TF_binding_site together are regulatorily active. (cls, SO:SG)
         | 
| 1446 1446 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000727)
         | 
| 1447 1447 | 
             
                    """
         | 
| 1448 | 
            -
                    return  | 
| 1448 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000727')
         | 
| 1449 1449 |  | 
| 1450 1450 | 
             
                @classmethod
         | 
| 1451 1451 | 
             
                def gap(cls):
         | 
| 1452 1452 | 
             
                    """A gap in the sequence of known length. The unknown bases are filled in with N's. (cls, SO:ke)
         | 
| 1453 1453 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000730)
         | 
| 1454 1454 | 
             
                    """
         | 
| 1455 | 
            -
                    return  | 
| 1455 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000730')
         | 
| 1456 1456 |  | 
| 1457 1457 | 
             
                @classmethod
         | 
| 1458 1458 | 
             
                def gene_group_regulatory_region(cls):
         | 
| 1459 | 
            -
                    return  | 
| 1459 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000752')
         | 
| 1460 1460 |  | 
| 1461 1461 | 
             
                @classmethod
         | 
| 1462 1462 | 
             
                def clone_insert(cls):
         | 
| 1463 1463 | 
             
                    """The region of sequence that has been inserted and is being propagated by the clone. (cls, SO:ke)
         | 
| 1464 1464 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000753)
         | 
| 1465 1465 | 
             
                    """
         | 
| 1466 | 
            -
                    return  | 
| 1466 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000753')
         | 
| 1467 1467 |  | 
| 1468 1468 | 
             
                @classmethod
         | 
| 1469 1469 | 
             
                def pseudogenic_rRNA(cls):
         | 
| 1470 1470 | 
             
                    """A non functional descendent of an rRNA. (cls, SO:ke)
         | 
| 1471 1471 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000777)
         | 
| 1472 1472 | 
             
                    """
         | 
| 1473 | 
            -
                    return  | 
| 1473 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000777')
         | 
| 1474 1474 |  | 
| 1475 1475 | 
             
                @classmethod
         | 
| 1476 1476 | 
             
                def pseudogenic_tRNA(cls):
         | 
| 1477 1477 | 
             
                    """A non functional descendent of a tRNA. (cls, SO:ke)
         | 
| 1478 1478 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000778)
         | 
| 1479 1479 | 
             
                    """
         | 
| 1480 | 
            -
                    return  | 
| 1480 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000778')
         | 
| 1481 1481 |  | 
| 1482 1482 | 
             
                @classmethod
         | 
| 1483 1483 | 
             
                def chromosome_part(cls):
         | 
| 1484 1484 | 
             
                    """A region of a chromosome. (cls, SO:ke)
         | 
| 1485 1485 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000830)
         | 
| 1486 1486 | 
             
                    """
         | 
| 1487 | 
            -
                    return  | 
| 1487 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000830')
         | 
| 1488 1488 |  | 
| 1489 1489 | 
             
                @classmethod
         | 
| 1490 1490 | 
             
                def gene_member_region(cls):
         | 
| 1491 1491 | 
             
                    """A region of a gene. (cls, SO:ke)
         | 
| 1492 1492 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000831)
         | 
| 1493 1493 | 
             
                    """
         | 
| 1494 | 
            -
                    return  | 
| 1494 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000831')
         | 
| 1495 1495 |  | 
| 1496 1496 | 
             
                @classmethod
         | 
| 1497 1497 | 
             
                def transcript_region(cls):
         | 
| 1498 1498 | 
             
                    """A region of a transcript. (cls, SO:ke)
         | 
| 1499 1499 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000833)
         | 
| 1500 1500 | 
             
                    """
         | 
| 1501 | 
            -
                    return  | 
| 1501 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000833')
         | 
| 1502 1502 |  | 
| 1503 1503 | 
             
                @classmethod
         | 
| 1504 1504 | 
             
                def mature_transcript_region(cls):
         | 
| 1505 1505 | 
             
                    """A region of a mature transcript. (cls, SO:ke)
         | 
| 1506 1506 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000834)
         | 
| 1507 1507 | 
             
                    """
         | 
| 1508 | 
            -
                    return  | 
| 1508 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000834')
         | 
| 1509 1509 |  | 
| 1510 1510 | 
             
                @classmethod
         | 
| 1511 1511 | 
             
                def primary_transcript_region(cls):
         | 
| 1512 1512 | 
             
                    """A part of a primary transcript. (cls, SO:ke)
         | 
| 1513 1513 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000835)
         | 
| 1514 1514 | 
             
                    """
         | 
| 1515 | 
            -
                    return  | 
| 1515 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000835')
         | 
| 1516 1516 |  | 
| 1517 1517 | 
             
                @classmethod
         | 
| 1518 1518 | 
             
                def mRNA_region(cls):
         | 
| 1519 1519 | 
             
                    """A region of an mRNA. (cls, SO:cb)
         | 
| 1520 1520 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000836)
         | 
| 1521 1521 | 
             
                    """
         | 
| 1522 | 
            -
                    return  | 
| 1522 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000836')
         | 
| 1523 1523 |  | 
| 1524 1524 | 
             
                @classmethod
         | 
| 1525 1525 | 
             
                def UTR_region(cls):
         | 
| 1526 1526 | 
             
                    """A region of UTR. (cls, SO:ke)
         | 
| 1527 1527 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000837)
         | 
| 1528 1528 | 
             
                    """
         | 
| 1529 | 
            -
                    return  | 
| 1529 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000837')
         | 
| 1530 1530 |  | 
| 1531 1531 | 
             
                @classmethod
         | 
| 1532 1532 | 
             
                def polypeptide_region(cls):
         | 
| 1533 1533 | 
             
                    """Biological sequence region that can be assigned to a specific subsequence of a polypeptide. (cls, SO:GAR, SO:ke)
         | 
| 1534 1534 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000839)
         | 
| 1535 1535 | 
             
                    """
         | 
| 1536 | 
            -
                    return  | 
| 1536 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000839')
         | 
| 1537 1537 |  | 
| 1538 1538 | 
             
                @classmethod
         | 
| 1539 1539 | 
             
                def spliceosomal_intron_region(cls):
         | 
| 1540 1540 | 
             
                    """A region within an intron. (cls, SO:ke)
         | 
| 1541 1541 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000841)
         | 
| 1542 1542 | 
             
                    """
         | 
| 1543 | 
            -
                    return  | 
| 1543 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000841')
         | 
| 1544 1544 |  | 
| 1545 1545 | 
             
                @classmethod
         | 
| 1546 1546 | 
             
                def gene_component_region(cls):
         | 
| 1547 | 
            -
                    return  | 
| 1547 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000842')
         | 
| 1548 1548 |  | 
| 1549 1549 | 
             
                @classmethod
         | 
| 1550 1550 | 
             
                def CDS_region(cls):
         | 
| 1551 1551 | 
             
                    """A region of a CDS. (cls, SO:cb)
         | 
| 1552 1552 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000851)
         | 
| 1553 1553 | 
             
                    """
         | 
| 1554 | 
            -
                    return  | 
| 1554 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000851')
         | 
| 1555 1555 |  | 
| 1556 1556 | 
             
                @classmethod
         | 
| 1557 1557 | 
             
                def exon_region(cls):
         | 
| 1558 1558 | 
             
                    """A region of an exon. (cls, RSC:cb)
         | 
| 1559 1559 | 
             
                    (http://purl.obolibrary.org/obo/SO_0000852)
         | 
| 1560 1560 | 
             
                    """
         | 
| 1561 | 
            -
                    return  | 
| 1561 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000852')
         | 
| 1562 1562 |  | 
| 1563 1563 | 
             
                @classmethod
         | 
| 1564 1564 | 
             
                def rRNA_16S(cls):
         | 
| 1565 1565 | 
             
                    """A large polynucleotide in Bacteria and Archaea, which functions as the small subunit of the ribosome. (cls, SO:ke)
         | 
| 1566 1566 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001000)
         | 
| 1567 1567 | 
             
                    """
         | 
| 1568 | 
            -
                    return  | 
| 1568 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001000')
         | 
| 1569 1569 |  | 
| 1570 1570 | 
             
                @classmethod
         | 
| 1571 1571 | 
             
                def rRNA_23S(cls):
         | 
| 1572 1572 | 
             
                    """A large polynucleotide in Bacteria and Archaea, which functions as the large subunit of the ribosome. (cls, SO:ke)
         | 
| 1573 1573 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001001)
         | 
| 1574 1574 | 
             
                    """
         | 
| 1575 | 
            -
                    return  | 
| 1575 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001001')
         | 
| 1576 1576 |  | 
| 1577 1577 | 
             
                @classmethod
         | 
| 1578 1578 | 
             
                def rRNA_25S(cls):
         | 
| 1579 1579 | 
             
                    """A large polynucleotide which functions as part of the large subunit of the ribosome in some eukaryotes. (cls, RSC:cb)
         | 
| 1580 1580 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001002)
         | 
| 1581 1581 | 
             
                    """
         | 
| 1582 | 
            -
                    return  | 
| 1582 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001002')
         | 
| 1583 1583 |  | 
| 1584 1584 | 
             
                @classmethod
         | 
| 1585 1585 | 
             
                def copy_number_variation(cls):
         | 
| 1586 1586 | 
             
                    """A variation that increases or decreases the copy number of a given region. (cls, SO:ke)
         | 
| 1587 1587 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001019)
         | 
| 1588 1588 | 
             
                    """
         | 
| 1589 | 
            -
                    return  | 
| 1589 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001019')
         | 
| 1590 1590 |  | 
| 1591 1591 | 
             
                @classmethod
         | 
| 1592 1592 | 
             
                def mobile_genetic_element(cls):
         | 
| 1593 1593 | 
             
                    """A nucleotide region with either intra-genome or intracellular moblity, of varying length, which often carry the information necessary for transfer and recombination with the host genome. (cls, PMID:14681355)
         | 
| 1594 1594 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001037)
         | 
| 1595 1595 | 
             
                    """
         | 
| 1596 | 
            -
                    return  | 
| 1596 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001037')
         | 
| 1597 1597 |  | 
| 1598 1598 | 
             
                @classmethod
         | 
| 1599 1599 | 
             
                def integrated_mobile_genetic_element(cls):
         | 
| 1600 1600 | 
             
                    """An MGE that is integrated into the host chromosome. (cls, SO:ke)
         | 
| 1601 1601 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001039)
         | 
| 1602 1602 | 
             
                    """
         | 
| 1603 | 
            -
                    return  | 
| 1603 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001039')
         | 
| 1604 1604 |  | 
| 1605 1605 | 
             
                @classmethod
         | 
| 1606 1606 | 
             
                def transcriptional_cis_regulatory_region(cls):
         | 
| 1607 1607 | 
             
                    """A regulatory_region that modulates the transcription of a gene or genes. (cls, SO:regcreative)
         | 
| 1608 1608 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001055)
         | 
| 1609 1609 | 
             
                    """
         | 
| 1610 | 
            -
                    return  | 
| 1610 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001055')
         | 
| 1611 1611 |  | 
| 1612 1612 | 
             
                @classmethod
         | 
| 1613 1613 | 
             
                def splicing_regulatory_region(cls):
         | 
| 1614 1614 | 
             
                    """A regulatory_region that modulates splicing. (cls, SO:ke)
         | 
| 1615 1615 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001056)
         | 
| 1616 1616 | 
             
                    """
         | 
| 1617 | 
            -
                    return  | 
| 1617 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001056')
         | 
| 1618 1618 |  | 
| 1619 1619 | 
             
                @classmethod
         | 
| 1620 1620 | 
             
                def sequence_alteration(cls):
         | 
| 1621 1621 | 
             
                    """A sequence_alteration is a sequence_feature whose extent is the deviation from another sequence. (cls, SO:ke)
         | 
| 1622 1622 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001059)
         | 
| 1623 1623 | 
             
                    """
         | 
| 1624 | 
            -
                    return  | 
| 1624 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001059')
         | 
| 1625 1625 |  | 
| 1626 1626 | 
             
                @classmethod
         | 
| 1627 1627 | 
             
                def immature_peptide_region(cls):
         | 
| 1628 1628 | 
             
                    """An immature_peptide_region is the extent of the peptide after it has been translated and before any processing occurs. (cls, EBIBS:GAR)
         | 
| 1629 1629 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001063)
         | 
| 1630 1630 | 
             
                    """
         | 
| 1631 | 
            -
                    return  | 
| 1631 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001063')
         | 
| 1632 1632 |  | 
| 1633 1633 | 
             
                @classmethod
         | 
| 1634 1634 | 
             
                def noncoding_region_of_exon(cls):
         | 
| 1635 1635 | 
             
                    """The maximal intersection of exon and UTR. (cls, SO:ke)
         | 
| 1636 1636 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001214)
         | 
| 1637 1637 | 
             
                    """
         | 
| 1638 | 
            -
                    return  | 
| 1638 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001214')
         | 
| 1639 1639 |  | 
| 1640 1640 | 
             
                @classmethod
         | 
| 1641 1641 | 
             
                def coding_region_of_exon(cls):
         | 
| 1642 1642 | 
             
                    """The region of an exon that encodes for protein sequence. (cls, SO:ke)
         | 
| 1643 1643 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001215)
         | 
| 1644 1644 | 
             
                    """
         | 
| 1645 | 
            -
                    return  | 
| 1645 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001215')
         | 
| 1646 1646 |  | 
| 1647 1647 | 
             
                @classmethod
         | 
| 1648 1648 | 
             
                def replicon(cls):
         | 
| 1649 1649 | 
             
                    """A region containing at least one unique origin of replication and a unique termination site. (cls, ISBN:0716719207)
         | 
| 1650 1650 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001235)
         | 
| 1651 1651 | 
             
                    """
         | 
| 1652 | 
            -
                    return  | 
| 1652 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001235')
         | 
| 1653 1653 |  | 
| 1654 1654 | 
             
                @classmethod
         | 
| 1655 1655 | 
             
                def base(cls):
         | 
| 1656 1656 | 
             
                    """A base is a sequence feature that corresponds to a single unit of a nucleotide polymer. (cls, SO:ke)
         | 
| 1657 1657 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001236)
         | 
| 1658 1658 | 
             
                    """
         | 
| 1659 | 
            -
                    return  | 
| 1659 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001236')
         | 
| 1660 1660 |  | 
| 1661 1661 | 
             
                @classmethod
         | 
| 1662 1662 | 
             
                def assembly(cls):
         | 
| 1663 1663 | 
             
                    """A region of the genome of known length that is composed by ordering and aligning two or more different regions. (cls, SO:ke)
         | 
| 1664 1664 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001248)
         | 
| 1665 1665 | 
             
                    """
         | 
| 1666 | 
            -
                    return  | 
| 1666 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001248')
         | 
| 1667 1667 |  | 
| 1668 1668 | 
             
                @classmethod
         | 
| 1669 1669 | 
             
                def biomaterial_region(cls):
         | 
| 1670 1670 | 
             
                    """A region which is intended for use in an experiment. (cls, SO:cb)
         | 
| 1671 1671 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001409)
         | 
| 1672 1672 | 
             
                    """
         | 
| 1673 | 
            -
                    return  | 
| 1673 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001409')
         | 
| 1674 1674 |  | 
| 1675 1675 | 
             
                @classmethod
         | 
| 1676 1676 | 
             
                def experimental_feature(cls):
         | 
| 1677 1677 | 
             
                    """A region which is the result of some arbitrary experimental procedure. The procedure may be carried out with biological material or inside a computer. (cls, SO:cb)
         | 
| 1678 1678 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001410)
         | 
| 1679 1679 | 
             
                    """
         | 
| 1680 | 
            -
                    return  | 
| 1680 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001410')
         | 
| 1681 1681 |  | 
| 1682 1682 | 
             
                @classmethod
         | 
| 1683 1683 | 
             
                def biological_region(cls):
         | 
| 1684 1684 | 
             
                    """A region defined by its disposition to be involved in a biological process. (cls, SO:cb)
         | 
| 1685 1685 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001411)
         | 
| 1686 1686 | 
             
                    """
         | 
| 1687 | 
            -
                    return  | 
| 1687 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001411')
         | 
| 1688 1688 |  | 
| 1689 1689 | 
             
                @classmethod
         | 
| 1690 1690 | 
             
                def topologically_defined_region(cls):
         | 
| 1691 1691 | 
             
                    """A region that is defined according to its relations with other regions within the same sequence. (cls, SO:cb)
         | 
| 1692 1692 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001412)
         | 
| 1693 1693 | 
             
                    """
         | 
| 1694 | 
            -
                    return  | 
| 1694 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001412')
         | 
| 1695 1695 |  | 
| 1696 1696 | 
             
                @classmethod
         | 
| 1697 1697 | 
             
                def cis_splice_site(cls):
         | 
| 1698 1698 | 
             
                    """Intronic 2 bp region bordering exon. A splice_site that adjacent_to exon and overlaps intron. (cls, SO:cjm, SO:ke)
         | 
| 1699 1699 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001419)
         | 
| 1700 1700 | 
             
                    """
         | 
| 1701 | 
            -
                    return  | 
| 1701 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001419')
         | 
| 1702 1702 |  | 
| 1703 1703 | 
             
                @classmethod
         | 
| 1704 1704 | 
             
                def trans_splice_site(cls):
         | 
| 1705 1705 | 
             
                    """Primary transcript region bordering trans-splice junction. (cls, SO:ke)
         | 
| 1706 1706 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001420)
         | 
| 1707 1707 | 
             
                    """
         | 
| 1708 | 
            -
                    return  | 
| 1708 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001420')
         | 
| 1709 1709 |  | 
| 1710 1710 | 
             
                @classmethod
         | 
| 1711 1711 | 
             
                def SNV(cls):
         | 
| 1712 1712 | 
             
                    """SNVs are single nucleotide positions in genomic DNA at which different sequence alternatives exist. (cls, SO:bm)
         | 
| 1713 1713 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001483)
         | 
| 1714 1714 | 
             
                    """
         | 
| 1715 | 
            -
                    return  | 
| 1715 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001483')
         | 
| 1716 1716 |  | 
| 1717 1717 | 
             
                @classmethod
         | 
| 1718 1718 | 
             
                def peptide_localization_signal(cls):
         | 
| 1719 1719 | 
             
                    """A region of peptide sequence used to target the polypeptide molecule to a specific organelle. (cls, SO:ke)
         | 
| 1720 1720 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001527)
         | 
| 1721 1721 | 
             
                    """
         | 
| 1722 | 
            -
                    return  | 
| 1722 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001527')
         | 
| 1723 1723 |  | 
| 1724 1724 | 
             
                @classmethod
         | 
| 1725 1725 | 
             
                def kozak_sequence(cls):
         | 
| 1726 1726 | 
             
                    """A kind of ribosome entry site, specific to Eukaryotic organisms that overlaps part of both 5' UTR and CDS sequence. (cls, SO:ke)
         | 
| 1727 1727 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001647)
         | 
| 1728 1728 | 
             
                    """
         | 
| 1729 | 
            -
                    return  | 
| 1729 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001647')
         | 
| 1730 1730 |  | 
| 1731 1731 | 
             
                @classmethod
         | 
| 1732 1732 | 
             
                def nucleotide_to_protein_binding_site(cls):
         | 
| 1733 1733 | 
             
                    """A binding site that, in the nucleotide molecule, interacts selectively and non-covalently with polypeptide residues. (cls, SO:ke)
         | 
| 1734 1734 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001654)
         | 
| 1735 1735 | 
             
                    """
         | 
| 1736 | 
            -
                    return  | 
| 1736 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001654')
         | 
| 1737 1737 |  | 
| 1738 1738 | 
             
                @classmethod
         | 
| 1739 1739 | 
             
                def transcription_regulatory_region(cls):
         | 
| 1740 1740 | 
             
                    """A regulatory region that is involved in the control of the process of transcription. (cls, SO:ke)
         | 
| 1741 1741 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001679)
         | 
| 1742 1742 | 
             
                    """
         | 
| 1743 | 
            -
                    return  | 
| 1743 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001679')
         | 
| 1744 1744 |  | 
| 1745 1745 | 
             
                @classmethod
         | 
| 1746 1746 | 
             
                def sequence_motif(cls):
         | 
| 1747 1747 | 
             
                    """A sequence motif is a nucleotide or amino-acid sequence pattern that may have biological significance. (cls, http://en.wikipedia.org/wiki/Sequence_motif)
         | 
| 1748 1748 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001683)
         | 
| 1749 1749 | 
             
                    """
         | 
| 1750 | 
            -
                    return  | 
| 1750 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001683')
         | 
| 1751 1751 |  | 
| 1752 1752 | 
             
                @classmethod
         | 
| 1753 1753 | 
             
                def epigenetically_modified_region(cls):
         | 
| 1754 1754 | 
             
                    """A biological region implicated in inherited changes caused by mechanisms other than changes in the underlying DNA sequence. (cls, http://en.wikipedia.org/wiki/Epigenetics, SO:ke)
         | 
| 1755 1755 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001720)
         | 
| 1756 1756 | 
             
                    """
         | 
| 1757 | 
            -
                    return  | 
| 1757 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001720')
         | 
| 1758 1758 |  | 
| 1759 1759 | 
             
                @classmethod
         | 
| 1760 1760 | 
             
                def paired_end_fragment(cls):
         | 
| 1761 1761 | 
             
                    """An assembly region that has been sequenced from both ends resulting in a read_pair (cls, mate_pair). (SO:ke)
         | 
| 1762 1762 | 
             
                    (http://purl.obolibrary.org/obo/SO_0001790)
         | 
| 1763 1763 | 
             
                    """
         | 
| 1764 | 
            -
                    return  | 
| 1764 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001790')
         | 
| 1765 1765 |  | 
| 1766 1766 | 
             
                @classmethod
         | 
| 1767 1767 | 
             
                def regulatory_region(cls):
         | 
| 1768 1768 | 
             
                    """A region of sequence that is involved in the control of a biological process. (cls, SO:ke)
         | 
| 1769 1769 | 
             
                    (http://purl.obolibrary.org/obo/SO_0005836)
         | 
| 1770 1770 | 
             
                    """
         | 
| 1771 | 
            -
                    return  | 
| 1771 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0005836')
         | 
| 1772 1772 |  | 
| 1773 1773 | 
             
                @classmethod
         | 
| 1774 1774 | 
             
                def gene_group(cls):
         | 
| 1775 1775 | 
             
                    """A collection of related genes. (cls, SO:ma)
         | 
| 1776 1776 | 
             
                    (http://purl.obolibrary.org/obo/SO_0005855)
         | 
| 1777 1777 | 
             
                    """
         | 
| 1778 | 
            -
                    return  | 
| 1778 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0005855')
         | 
| 1779 1779 |  | 
| 1780 1780 | 
             
                @classmethod
         | 
| 1781 1781 | 
             
                def cleaved_peptide_region(cls):
         | 
| 1782 1782 | 
             
                    """The cleaved_peptide_regon is the a region of peptide sequence that is cleaved during maturation. (cls, EBIBS:GAR)
         | 
| 1783 1783 | 
             
                    (http://purl.obolibrary.org/obo/SO_0100011)
         | 
| 1784 1784 | 
             
                    """
         | 
| 1785 | 
            -
                    return  | 
| 1785 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0100011')
         | 
| 1786 1786 |  | 
| 1787 1787 | 
             
                @classmethod
         | 
| 1788 1788 | 
             
                def substitution(cls):
         | 
| 1789 1789 | 
             
                    """A sequence alteration where the length of the change in the variant is the same as that of the reference. (cls, SO:ke)
         | 
| 1790 1790 | 
             
                    (http://purl.obolibrary.org/obo/SO_1000002)
         | 
| 1791 1791 | 
             
                    """
         | 
| 1792 | 
            -
                    return  | 
| 1792 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_1000002')
         | 
| 1793 1793 |  | 
| 1794 1794 | 
             
                @classmethod
         | 
| 1795 1795 | 
             
                def complex_substitution(cls):
         | 
| 1796 1796 | 
             
                    """When no simple or well defined DNA mutation event describes the observed DNA change, the keyword \"complex\" should be used. Usually there are multiple equally plausible explanations for the change. (cls, EBI:www.ebi.ac.uk/mutations/recommendations/mutevent.html)
         | 
| 1797 1797 | 
             
                    (http://purl.obolibrary.org/obo/SO_1000005)
         | 
| 1798 1798 | 
             
                    """
         | 
| 1799 | 
            -
                    return  | 
| 1799 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_1000005')
         | 
| 1800 1800 |  | 
| 1801 1801 | 
             
                @classmethod
         | 
| 1802 1802 | 
             
                def point_mutation(cls):
         | 
| 1803 1803 | 
             
                    """A single nucleotide change which has occurred at the same position of a corresponding nucleotide in a reference sequence. (cls, SO:immuno_workshop)
         | 
| 1804 1804 | 
             
                    (http://purl.obolibrary.org/obo/SO_1000008)
         | 
| 1805 1805 | 
             
                    """
         | 
| 1806 | 
            -
                    return  | 
| 1806 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_1000008')
         | 
| 1807 1807 |  | 
| 1808 1808 | 
             
                @classmethod
         | 
| 1809 1809 | 
             
                def inversion(cls):
         | 
| 1810 1810 | 
             
                    """A continuous nucleotide sequence is inverted in the same position. (cls, EBI:www.ebi.ac.uk/mutations/recommendations/mutevent.html)
         | 
| 1811 1811 | 
             
                    (http://purl.obolibrary.org/obo/SO_1000036)
         | 
| 1812 1812 | 
             
                    """
         | 
| 1813 | 
            -
                    return  | 
| 1813 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_1000036')
         | 
| 1814 1814 |  | 
| 1815 1815 | 
             
                @classmethod
         | 
| 1816 1816 | 
             
                def regulon(cls):
         | 
| 1817 1817 | 
             
                    """A group of genes, whether linked as a cluster or not, that respond to a common regulatory signal. (cls, ISBN:0198506732)
         | 
| 1818 1818 | 
             
                    (http://purl.obolibrary.org/obo/SO_1001284)
         | 
| 1819 1819 | 
             
                    """
         | 
| 1820 | 
            -
                    return  | 
| 1820 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_1001284')
         | 
| 1821 1821 |  | 
| 1822 1822 | 
             
                @classmethod
         | 
| 1823 1823 | 
             
                def databank_entry(cls):
         | 
| 1824 1824 | 
             
                    """The sequence referred to by an entry in a databank such as Genbank or SwissProt. (cls, SO:ke)
         | 
| 1825 1825 | 
             
                    (http://purl.obolibrary.org/obo/SO_2000061)
         | 
| 1826 1826 | 
             
                    """
         | 
| 1827 | 
            -
                    return  | 
| 1827 | 
            +
                    return _namespace_SOFA('http://purl.obolibrary.org/obo/SO_2000061')
         | 
| 1828 1828 |  | 
| 1829 1829 | 
             
                @classmethod
         | 
| 1830 1830 | 
             
                def is_object_property(cls, uri):
         | 
| @@ -1832,39 +1832,39 @@ class SOFO: | |
| 1832 1832 |  | 
| 1833 1833 | 
             
                    uri -- URI that is tested for being an object property
         | 
| 1834 1834 | 
             
                    """
         | 
| 1835 | 
            -
                    if uri ==  | 
| 1835 | 
            +
                    if uri == _namespace_SOFA(''):
         | 
| 1836 1836 | 
             
                        return True
         | 
| 1837 | 
            -
                    if uri ==  | 
| 1837 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:complete_evidence_for_feature'):
         | 
| 1838 1838 | 
             
                        return True
         | 
| 1839 | 
            -
                    if uri ==  | 
| 1839 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:contained_by'):
         | 
| 1840 1840 | 
             
                        return True
         | 
| 1841 | 
            -
                    if uri ==  | 
| 1841 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:contains'):
         | 
| 1842 1842 | 
             
                        return True
         | 
| 1843 | 
            -
                    if uri ==  | 
| 1843 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:derives_from'):
         | 
| 1844 1844 | 
             
                        return True
         | 
| 1845 | 
            -
                    if uri ==  | 
| 1845 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:evidence_for_feature'):
         | 
| 1846 1846 | 
             
                        return True
         | 
| 1847 | 
            -
                    if uri ==  | 
| 1847 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_integral_part'):
         | 
| 1848 1848 | 
             
                        return True
         | 
| 1849 | 
            -
                    if uri ==  | 
| 1849 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_part'):
         | 
| 1850 1850 | 
             
                        return True
         | 
| 1851 | 
            -
                    if uri ==  | 
| 1851 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:homologous_to'):
         | 
| 1852 1852 | 
             
                        return True
         | 
| 1853 | 
            -
                    if uri ==  | 
| 1853 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:integral_part_of'):
         | 
| 1854 1854 | 
             
                        return True
         | 
| 1855 | 
            -
                    if uri ==  | 
| 1855 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:member_of'):
         | 
| 1856 1856 | 
             
                        return True
         | 
| 1857 | 
            -
                    if uri ==  | 
| 1857 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:non_functional_homolog_of'):
         | 
| 1858 1858 | 
             
                        return True
         | 
| 1859 | 
            -
                    if uri ==  | 
| 1859 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:orthologous_to'):
         | 
| 1860 1860 | 
             
                        return True
         | 
| 1861 | 
            -
                    if uri ==  | 
| 1861 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:paralogous_to'):
         | 
| 1862 1862 | 
             
                        return True
         | 
| 1863 | 
            -
                    if uri ==  | 
| 1863 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:part_of'):
         | 
| 1864 1864 | 
             
                        return True
         | 
| 1865 | 
            -
                    if uri ==  | 
| 1865 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:partial_evidence_for_feature'):
         | 
| 1866 1866 | 
             
                        return True
         | 
| 1867 | 
            -
                    if uri ==  | 
| 1867 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:similar_to'):
         | 
| 1868 1868 | 
             
                        return True
         | 
| 1869 1869 | 
             
                    return False
         | 
| 1870 1870 |  | 
| @@ -1882,509 +1882,509 @@ class SOFO: | |
| 1882 1882 |  | 
| 1883 1883 | 
             
                    uri -- URI that is tested for being a class
         | 
| 1884 1884 | 
             
                    """
         | 
| 1885 | 
            -
                    if uri ==  | 
| 1885 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000000'):
         | 
| 1886 1886 | 
             
                        return True
         | 
| 1887 | 
            -
                    if uri ==  | 
| 1887 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000001'):
         | 
| 1888 1888 | 
             
                        return True
         | 
| 1889 | 
            -
                    if uri ==  | 
| 1889 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000004'):
         | 
| 1890 1890 | 
             
                        return True
         | 
| 1891 | 
            -
                    if uri ==  | 
| 1891 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000005'):
         | 
| 1892 1892 | 
             
                        return True
         | 
| 1893 | 
            -
                    if uri ==  | 
| 1893 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000006'):
         | 
| 1894 1894 | 
             
                        return True
         | 
| 1895 | 
            -
                    if uri ==  | 
| 1895 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000007'):
         | 
| 1896 1896 | 
             
                        return True
         | 
| 1897 | 
            -
                    if uri ==  | 
| 1897 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000013'):
         | 
| 1898 1898 | 
             
                        return True
         | 
| 1899 | 
            -
                    if uri ==  | 
| 1899 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000038'):
         | 
| 1900 1900 | 
             
                        return True
         | 
| 1901 | 
            -
                    if uri ==  | 
| 1901 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000039'):
         | 
| 1902 1902 | 
             
                        return True
         | 
| 1903 | 
            -
                    if uri ==  | 
| 1903 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000050'):
         | 
| 1904 1904 | 
             
                        return True
         | 
| 1905 | 
            -
                    if uri ==  | 
| 1905 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000057'):
         | 
| 1906 1906 | 
             
                        return True
         | 
| 1907 | 
            -
                    if uri ==  | 
| 1907 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000059'):
         | 
| 1908 1908 | 
             
                        return True
         | 
| 1909 | 
            -
                    if uri ==  | 
| 1909 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000101'):
         | 
| 1910 1910 | 
             
                        return True
         | 
| 1911 | 
            -
                    if uri ==  | 
| 1911 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000102'):
         | 
| 1912 1912 | 
             
                        return True
         | 
| 1913 | 
            -
                    if uri ==  | 
| 1913 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000103'):
         | 
| 1914 1914 | 
             
                        return True
         | 
| 1915 | 
            -
                    if uri ==  | 
| 1915 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000104'):
         | 
| 1916 1916 | 
             
                        return True
         | 
| 1917 | 
            -
                    if uri ==  | 
| 1917 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000109'):
         | 
| 1918 1918 | 
             
                        return True
         | 
| 1919 | 
            -
                    if uri ==  | 
| 1919 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000110'):
         | 
| 1920 1920 | 
             
                        return True
         | 
| 1921 | 
            -
                    if uri ==  | 
| 1921 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000112'):
         | 
| 1922 1922 | 
             
                        return True
         | 
| 1923 | 
            -
                    if uri ==  | 
| 1923 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000113'):
         | 
| 1924 1924 | 
             
                        return True
         | 
| 1925 | 
            -
                    if uri ==  | 
| 1925 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000114'):
         | 
| 1926 1926 | 
             
                        return True
         | 
| 1927 | 
            -
                    if uri ==  | 
| 1927 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000120'):
         | 
| 1928 1928 | 
             
                        return True
         | 
| 1929 | 
            -
                    if uri ==  | 
| 1929 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000139'):
         | 
| 1930 1930 | 
             
                        return True
         | 
| 1931 | 
            -
                    if uri ==  | 
| 1931 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000140'):
         | 
| 1932 1932 | 
             
                        return True
         | 
| 1933 | 
            -
                    if uri ==  | 
| 1933 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000141'):
         | 
| 1934 1934 | 
             
                        return True
         | 
| 1935 | 
            -
                    if uri ==  | 
| 1935 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000143'):
         | 
| 1936 1936 | 
             
                        return True
         | 
| 1937 | 
            -
                    if uri ==  | 
| 1937 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000147'):
         | 
| 1938 1938 | 
             
                        return True
         | 
| 1939 | 
            -
                    if uri ==  | 
| 1939 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000148'):
         | 
| 1940 1940 | 
             
                        return True
         | 
| 1941 | 
            -
                    if uri ==  | 
| 1941 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000149'):
         | 
| 1942 1942 | 
             
                        return True
         | 
| 1943 | 
            -
                    if uri ==  | 
| 1943 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000150'):
         | 
| 1944 1944 | 
             
                        return True
         | 
| 1945 | 
            -
                    if uri ==  | 
| 1945 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000151'):
         | 
| 1946 1946 | 
             
                        return True
         | 
| 1947 | 
            -
                    if uri ==  | 
| 1947 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000159'):
         | 
| 1948 1948 | 
             
                        return True
         | 
| 1949 | 
            -
                    if uri ==  | 
| 1949 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000161'):
         | 
| 1950 1950 | 
             
                        return True
         | 
| 1951 | 
            -
                    if uri ==  | 
| 1951 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000162'):
         | 
| 1952 1952 | 
             
                        return True
         | 
| 1953 | 
            -
                    if uri ==  | 
| 1953 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000163'):
         | 
| 1954 1954 | 
             
                        return True
         | 
| 1955 | 
            -
                    if uri ==  | 
| 1955 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000164'):
         | 
| 1956 1956 | 
             
                        return True
         | 
| 1957 | 
            -
                    if uri ==  | 
| 1957 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000165'):
         | 
| 1958 1958 | 
             
                        return True
         | 
| 1959 | 
            -
                    if uri ==  | 
| 1959 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000167'):
         | 
| 1960 1960 | 
             
                        return True
         | 
| 1961 | 
            -
                    if uri ==  | 
| 1961 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000177'):
         | 
| 1962 1962 | 
             
                        return True
         | 
| 1963 | 
            -
                    if uri ==  | 
| 1963 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000178'):
         | 
| 1964 1964 | 
             
                        return True
         | 
| 1965 | 
            -
                    if uri ==  | 
| 1965 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000179'):
         | 
| 1966 1966 | 
             
                        return True
         | 
| 1967 | 
            -
                    if uri ==  | 
| 1967 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000181'):
         | 
| 1968 1968 | 
             
                        return True
         | 
| 1969 | 
            -
                    if uri ==  | 
| 1969 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000183'):
         | 
| 1970 1970 | 
             
                        return True
         | 
| 1971 | 
            -
                    if uri ==  | 
| 1971 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000185'):
         | 
| 1972 1972 | 
             
                        return True
         | 
| 1973 | 
            -
                    if uri ==  | 
| 1973 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000187'):
         | 
| 1974 1974 | 
             
                        return True
         | 
| 1975 | 
            -
                    if uri ==  | 
| 1975 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000188'):
         | 
| 1976 1976 | 
             
                        return True
         | 
| 1977 | 
            -
                    if uri ==  | 
| 1977 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000193'):
         | 
| 1978 1978 | 
             
                        return True
         | 
| 1979 | 
            -
                    if uri ==  | 
| 1979 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000195'):
         | 
| 1980 1980 | 
             
                        return True
         | 
| 1981 | 
            -
                    if uri ==  | 
| 1981 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000196'):
         | 
| 1982 1982 | 
             
                        return True
         | 
| 1983 | 
            -
                    if uri ==  | 
| 1983 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000197'):
         | 
| 1984 1984 | 
             
                        return True
         | 
| 1985 | 
            -
                    if uri ==  | 
| 1985 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000198'):
         | 
| 1986 1986 | 
             
                        return True
         | 
| 1987 | 
            -
                    if uri ==  | 
| 1987 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000200'):
         | 
| 1988 1988 | 
             
                        return True
         | 
| 1989 | 
            -
                    if uri ==  | 
| 1989 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000203'):
         | 
| 1990 1990 | 
             
                        return True
         | 
| 1991 | 
            -
                    if uri ==  | 
| 1991 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000204'):
         | 
| 1992 1992 | 
             
                        return True
         | 
| 1993 | 
            -
                    if uri ==  | 
| 1993 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000205'):
         | 
| 1994 1994 | 
             
                        return True
         | 
| 1995 | 
            -
                    if uri ==  | 
| 1995 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000209'):
         | 
| 1996 1996 | 
             
                        return True
         | 
| 1997 | 
            -
                    if uri ==  | 
| 1997 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000233'):
         | 
| 1998 1998 | 
             
                        return True
         | 
| 1999 | 
            -
                    if uri ==  | 
| 1999 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000234'):
         | 
| 2000 2000 | 
             
                        return True
         | 
| 2001 | 
            -
                    if uri ==  | 
| 2001 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000235'):
         | 
| 2002 2002 | 
             
                        return True
         | 
| 2003 | 
            -
                    if uri ==  | 
| 2003 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000236'):
         | 
| 2004 2004 | 
             
                        return True
         | 
| 2005 | 
            -
                    if uri ==  | 
| 2005 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000239'):
         | 
| 2006 2006 | 
             
                        return True
         | 
| 2007 | 
            -
                    if uri ==  | 
| 2007 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000252'):
         | 
| 2008 2008 | 
             
                        return True
         | 
| 2009 | 
            -
                    if uri ==  | 
| 2009 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000253'):
         | 
| 2010 2010 | 
             
                        return True
         | 
| 2011 | 
            -
                    if uri ==  | 
| 2011 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000274'):
         | 
| 2012 2012 | 
             
                        return True
         | 
| 2013 | 
            -
                    if uri ==  | 
| 2013 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000275'):
         | 
| 2014 2014 | 
             
                        return True
         | 
| 2015 | 
            -
                    if uri ==  | 
| 2015 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000276'):
         | 
| 2016 2016 | 
             
                        return True
         | 
| 2017 | 
            -
                    if uri ==  | 
| 2017 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000289'):
         | 
| 2018 2018 | 
             
                        return True
         | 
| 2019 | 
            -
                    if uri ==  | 
| 2019 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000294'):
         | 
| 2020 2020 | 
             
                        return True
         | 
| 2021 | 
            -
                    if uri ==  | 
| 2021 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000296'):
         | 
| 2022 2022 | 
             
                        return True
         | 
| 2023 | 
            -
                    if uri ==  | 
| 2023 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000303'):
         | 
| 2024 2024 | 
             
                        return True
         | 
| 2025 | 
            -
                    if uri ==  | 
| 2025 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000305'):
         | 
| 2026 2026 | 
             
                        return True
         | 
| 2027 | 
            -
                    if uri ==  | 
| 2027 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000306'):
         | 
| 2028 2028 | 
             
                        return True
         | 
| 2029 | 
            -
                    if uri ==  | 
| 2029 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000307'):
         | 
| 2030 2030 | 
             
                        return True
         | 
| 2031 | 
            -
                    if uri ==  | 
| 2031 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000314'):
         | 
| 2032 2032 | 
             
                        return True
         | 
| 2033 | 
            -
                    if uri ==  | 
| 2033 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000315'):
         | 
| 2034 2034 | 
             
                        return True
         | 
| 2035 | 
            -
                    if uri ==  | 
| 2035 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000316'):
         | 
| 2036 2036 | 
             
                        return True
         | 
| 2037 | 
            -
                    if uri ==  | 
| 2037 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000318'):
         | 
| 2038 2038 | 
             
                        return True
         | 
| 2039 | 
            -
                    if uri ==  | 
| 2039 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000319'):
         | 
| 2040 2040 | 
             
                        return True
         | 
| 2041 | 
            -
                    if uri ==  | 
| 2041 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000324'):
         | 
| 2042 2042 | 
             
                        return True
         | 
| 2043 | 
            -
                    if uri ==  | 
| 2043 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000325'):
         | 
| 2044 2044 | 
             
                        return True
         | 
| 2045 | 
            -
                    if uri ==  | 
| 2045 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000326'):
         | 
| 2046 2046 | 
             
                        return True
         | 
| 2047 | 
            -
                    if uri ==  | 
| 2047 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000330'):
         | 
| 2048 2048 | 
             
                        return True
         | 
| 2049 | 
            -
                    if uri ==  | 
| 2049 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000331'):
         | 
| 2050 2050 | 
             
                        return True
         | 
| 2051 | 
            -
                    if uri ==  | 
| 2051 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000332'):
         | 
| 2052 2052 | 
             
                        return True
         | 
| 2053 | 
            -
                    if uri ==  | 
| 2053 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000333'):
         | 
| 2054 2054 | 
             
                        return True
         | 
| 2055 | 
            -
                    if uri ==  | 
| 2055 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000334'):
         | 
| 2056 2056 | 
             
                        return True
         | 
| 2057 | 
            -
                    if uri ==  | 
| 2057 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000336'):
         | 
| 2058 2058 | 
             
                        return True
         | 
| 2059 | 
            -
                    if uri ==  | 
| 2059 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000337'):
         | 
| 2060 2060 | 
             
                        return True
         | 
| 2061 | 
            -
                    if uri ==  | 
| 2061 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000340'):
         | 
| 2062 2062 | 
             
                        return True
         | 
| 2063 | 
            -
                    if uri ==  | 
| 2063 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000341'):
         | 
| 2064 2064 | 
             
                        return True
         | 
| 2065 | 
            -
                    if uri ==  | 
| 2065 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000343'):
         | 
| 2066 2066 | 
             
                        return True
         | 
| 2067 | 
            -
                    if uri ==  | 
| 2067 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000344'):
         | 
| 2068 2068 | 
             
                        return True
         | 
| 2069 | 
            -
                    if uri ==  | 
| 2069 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000345'):
         | 
| 2070 2070 | 
             
                        return True
         | 
| 2071 | 
            -
                    if uri ==  | 
| 2071 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000347'):
         | 
| 2072 2072 | 
             
                        return True
         | 
| 2073 | 
            -
                    if uri ==  | 
| 2073 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000349'):
         | 
| 2074 2074 | 
             
                        return True
         | 
| 2075 | 
            -
                    if uri ==  | 
| 2075 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000353'):
         | 
| 2076 2076 | 
             
                        return True
         | 
| 2077 | 
            -
                    if uri ==  | 
| 2077 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000360'):
         | 
| 2078 2078 | 
             
                        return True
         | 
| 2079 | 
            -
                    if uri ==  | 
| 2079 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000366'):
         | 
| 2080 2080 | 
             
                        return True
         | 
| 2081 | 
            -
                    if uri ==  | 
| 2081 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000368'):
         | 
| 2082 2082 | 
             
                        return True
         | 
| 2083 | 
            -
                    if uri ==  | 
| 2083 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000370'):
         | 
| 2084 2084 | 
             
                        return True
         | 
| 2085 | 
            -
                    if uri ==  | 
| 2085 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000372'):
         | 
| 2086 2086 | 
             
                        return True
         | 
| 2087 | 
            -
                    if uri ==  | 
| 2087 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000374'):
         | 
| 2088 2088 | 
             
                        return True
         | 
| 2089 | 
            -
                    if uri ==  | 
| 2089 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000375'):
         | 
| 2090 2090 | 
             
                        return True
         | 
| 2091 | 
            -
                    if uri ==  | 
| 2091 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000380'):
         | 
| 2092 2092 | 
             
                        return True
         | 
| 2093 | 
            -
                    if uri ==  | 
| 2093 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000385'):
         | 
| 2094 2094 | 
             
                        return True
         | 
| 2095 | 
            -
                    if uri ==  | 
| 2095 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000386'):
         | 
| 2096 2096 | 
             
                        return True
         | 
| 2097 | 
            -
                    if uri ==  | 
| 2097 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000390'):
         | 
| 2098 2098 | 
             
                        return True
         | 
| 2099 | 
            -
                    if uri ==  | 
| 2099 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000391'):
         | 
| 2100 2100 | 
             
                        return True
         | 
| 2101 | 
            -
                    if uri ==  | 
| 2101 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000392'):
         | 
| 2102 2102 | 
             
                        return True
         | 
| 2103 | 
            -
                    if uri ==  | 
| 2103 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000393'):
         | 
| 2104 2104 | 
             
                        return True
         | 
| 2105 | 
            -
                    if uri ==  | 
| 2105 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000394'):
         | 
| 2106 2106 | 
             
                        return True
         | 
| 2107 | 
            -
                    if uri ==  | 
| 2107 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000395'):
         | 
| 2108 2108 | 
             
                        return True
         | 
| 2109 | 
            -
                    if uri ==  | 
| 2109 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000396'):
         | 
| 2110 2110 | 
             
                        return True
         | 
| 2111 | 
            -
                    if uri ==  | 
| 2111 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000397'):
         | 
| 2112 2112 | 
             
                        return True
         | 
| 2113 | 
            -
                    if uri ==  | 
| 2113 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000398'):
         | 
| 2114 2114 | 
             
                        return True
         | 
| 2115 | 
            -
                    if uri ==  | 
| 2115 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000399'):
         | 
| 2116 2116 | 
             
                        return True
         | 
| 2117 | 
            -
                    if uri ==  | 
| 2117 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000403'):
         | 
| 2118 2118 | 
             
                        return True
         | 
| 2119 | 
            -
                    if uri ==  | 
| 2119 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000404'):
         | 
| 2120 2120 | 
             
                        return True
         | 
| 2121 | 
            -
                    if uri ==  | 
| 2121 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000405'):
         | 
| 2122 2122 | 
             
                        return True
         | 
| 2123 | 
            -
                    if uri ==  | 
| 2123 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000407'):
         | 
| 2124 2124 | 
             
                        return True
         | 
| 2125 | 
            -
                    if uri ==  | 
| 2125 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000409'):
         | 
| 2126 2126 | 
             
                        return True
         | 
| 2127 | 
            -
                    if uri ==  | 
| 2127 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000410'):
         | 
| 2128 2128 | 
             
                        return True
         | 
| 2129 | 
            -
                    if uri ==  | 
| 2129 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000412'):
         | 
| 2130 2130 | 
             
                        return True
         | 
| 2131 | 
            -
                    if uri ==  | 
| 2131 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000413'):
         | 
| 2132 2132 | 
             
                        return True
         | 
| 2133 | 
            -
                    if uri ==  | 
| 2133 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000418'):
         | 
| 2134 2134 | 
             
                        return True
         | 
| 2135 | 
            -
                    if uri ==  | 
| 2135 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000419'):
         | 
| 2136 2136 | 
             
                        return True
         | 
| 2137 | 
            -
                    if uri ==  | 
| 2137 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000436'):
         | 
| 2138 2138 | 
             
                        return True
         | 
| 2139 | 
            -
                    if uri ==  | 
| 2139 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000441'):
         | 
| 2140 2140 | 
             
                        return True
         | 
| 2141 | 
            -
                    if uri ==  | 
| 2141 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000442'):
         | 
| 2142 2142 | 
             
                        return True
         | 
| 2143 | 
            -
                    if uri ==  | 
| 2143 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000454'):
         | 
| 2144 2144 | 
             
                        return True
         | 
| 2145 | 
            -
                    if uri ==  | 
| 2145 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000462'):
         | 
| 2146 2146 | 
             
                        return True
         | 
| 2147 | 
            -
                    if uri ==  | 
| 2147 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000464'):
         | 
| 2148 2148 | 
             
                        return True
         | 
| 2149 | 
            -
                    if uri ==  | 
| 2149 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000468'):
         | 
| 2150 2150 | 
             
                        return True
         | 
| 2151 | 
            -
                    if uri ==  | 
| 2151 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000472'):
         | 
| 2152 2152 | 
             
                        return True
         | 
| 2153 | 
            -
                    if uri ==  | 
| 2153 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000474'):
         | 
| 2154 2154 | 
             
                        return True
         | 
| 2155 | 
            -
                    if uri ==  | 
| 2155 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000483'):
         | 
| 2156 2156 | 
             
                        return True
         | 
| 2157 | 
            -
                    if uri ==  | 
| 2157 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000484'):
         | 
| 2158 2158 | 
             
                        return True
         | 
| 2159 | 
            -
                    if uri ==  | 
| 2159 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000486'):
         | 
| 2160 2160 | 
             
                        return True
         | 
| 2161 | 
            -
                    if uri ==  | 
| 2161 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000499'):
         | 
| 2162 2162 | 
             
                        return True
         | 
| 2163 | 
            -
                    if uri ==  | 
| 2163 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000502'):
         | 
| 2164 2164 | 
             
                        return True
         | 
| 2165 | 
            -
                    if uri ==  | 
| 2165 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000551'):
         | 
| 2166 2166 | 
             
                        return True
         | 
| 2167 | 
            -
                    if uri ==  | 
| 2167 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000553'):
         | 
| 2168 2168 | 
             
                        return True
         | 
| 2169 | 
            -
                    if uri ==  | 
| 2169 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000577'):
         | 
| 2170 2170 | 
             
                        return True
         | 
| 2171 | 
            -
                    if uri ==  | 
| 2171 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000581'):
         | 
| 2172 2172 | 
             
                        return True
         | 
| 2173 | 
            -
                    if uri ==  | 
| 2173 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000587'):
         | 
| 2174 2174 | 
             
                        return True
         | 
| 2175 | 
            -
                    if uri ==  | 
| 2175 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000588'):
         | 
| 2176 2176 | 
             
                        return True
         | 
| 2177 | 
            -
                    if uri ==  | 
| 2177 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000590'):
         | 
| 2178 2178 | 
             
                        return True
         | 
| 2179 | 
            -
                    if uri ==  | 
| 2179 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000593'):
         | 
| 2180 2180 | 
             
                        return True
         | 
| 2181 | 
            -
                    if uri ==  | 
| 2181 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000602'):
         | 
| 2182 2182 | 
             
                        return True
         | 
| 2183 | 
            -
                    if uri ==  | 
| 2183 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000603'):
         | 
| 2184 2184 | 
             
                        return True
         | 
| 2185 | 
            -
                    if uri ==  | 
| 2185 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000605'):
         | 
| 2186 2186 | 
             
                        return True
         | 
| 2187 | 
            -
                    if uri ==  | 
| 2187 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000610'):
         | 
| 2188 2188 | 
             
                        return True
         | 
| 2189 | 
            -
                    if uri ==  | 
| 2189 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000611'):
         | 
| 2190 2190 | 
             
                        return True
         | 
| 2191 | 
            -
                    if uri ==  | 
| 2191 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000612'):
         | 
| 2192 2192 | 
             
                        return True
         | 
| 2193 | 
            -
                    if uri ==  | 
| 2193 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000616'):
         | 
| 2194 2194 | 
             
                        return True
         | 
| 2195 | 
            -
                    if uri ==  | 
| 2195 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000624'):
         | 
| 2196 2196 | 
             
                        return True
         | 
| 2197 | 
            -
                    if uri ==  | 
| 2197 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000625'):
         | 
| 2198 2198 | 
             
                        return True
         | 
| 2199 | 
            -
                    if uri ==  | 
| 2199 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000627'):
         | 
| 2200 2200 | 
             
                        return True
         | 
| 2201 | 
            -
                    if uri ==  | 
| 2201 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000628'):
         | 
| 2202 2202 | 
             
                        return True
         | 
| 2203 | 
            -
                    if uri ==  | 
| 2203 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000643'):
         | 
| 2204 2204 | 
             
                        return True
         | 
| 2205 | 
            -
                    if uri ==  | 
| 2205 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000644'):
         | 
| 2206 2206 | 
             
                        return True
         | 
| 2207 | 
            -
                    if uri ==  | 
| 2207 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000645'):
         | 
| 2208 2208 | 
             
                        return True
         | 
| 2209 | 
            -
                    if uri ==  | 
| 2209 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000646'):
         | 
| 2210 2210 | 
             
                        return True
         | 
| 2211 | 
            -
                    if uri ==  | 
| 2211 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000649'):
         | 
| 2212 2212 | 
             
                        return True
         | 
| 2213 | 
            -
                    if uri ==  | 
| 2213 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000650'):
         | 
| 2214 2214 | 
             
                        return True
         | 
| 2215 | 
            -
                    if uri ==  | 
| 2215 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000651'):
         | 
| 2216 2216 | 
             
                        return True
         | 
| 2217 | 
            -
                    if uri ==  | 
| 2217 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000652'):
         | 
| 2218 2218 | 
             
                        return True
         | 
| 2219 | 
            -
                    if uri ==  | 
| 2219 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000653'):
         | 
| 2220 2220 | 
             
                        return True
         | 
| 2221 | 
            -
                    if uri ==  | 
| 2221 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000655'):
         | 
| 2222 2222 | 
             
                        return True
         | 
| 2223 | 
            -
                    if uri ==  | 
| 2223 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000657'):
         | 
| 2224 2224 | 
             
                        return True
         | 
| 2225 | 
            -
                    if uri ==  | 
| 2225 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000658'):
         | 
| 2226 2226 | 
             
                        return True
         | 
| 2227 | 
            -
                    if uri ==  | 
| 2227 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000662'):
         | 
| 2228 2228 | 
             
                        return True
         | 
| 2229 | 
            -
                    if uri ==  | 
| 2229 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000667'):
         | 
| 2230 2230 | 
             
                        return True
         | 
| 2231 | 
            -
                    if uri ==  | 
| 2231 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000668'):
         | 
| 2232 2232 | 
             
                        return True
         | 
| 2233 | 
            -
                    if uri ==  | 
| 2233 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000673'):
         | 
| 2234 2234 | 
             
                        return True
         | 
| 2235 | 
            -
                    if uri ==  | 
| 2235 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000684'):
         | 
| 2236 2236 | 
             
                        return True
         | 
| 2237 | 
            -
                    if uri ==  | 
| 2237 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000687'):
         | 
| 2238 2238 | 
             
                        return True
         | 
| 2239 | 
            -
                    if uri ==  | 
| 2239 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000688'):
         | 
| 2240 2240 | 
             
                        return True
         | 
| 2241 | 
            -
                    if uri ==  | 
| 2241 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000689'):
         | 
| 2242 2242 | 
             
                        return True
         | 
| 2243 | 
            -
                    if uri ==  | 
| 2243 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000694'):
         | 
| 2244 2244 | 
             
                        return True
         | 
| 2245 | 
            -
                    if uri ==  | 
| 2245 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000695'):
         | 
| 2246 2246 | 
             
                        return True
         | 
| 2247 | 
            -
                    if uri ==  | 
| 2247 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000696'):
         | 
| 2248 2248 | 
             
                        return True
         | 
| 2249 | 
            -
                    if uri ==  | 
| 2249 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000699'):
         | 
| 2250 2250 | 
             
                        return True
         | 
| 2251 | 
            -
                    if uri ==  | 
| 2251 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000700'):
         | 
| 2252 2252 | 
             
                        return True
         | 
| 2253 | 
            -
                    if uri ==  | 
| 2253 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000701'):
         | 
| 2254 2254 | 
             
                        return True
         | 
| 2255 | 
            -
                    if uri ==  | 
| 2255 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000702'):
         | 
| 2256 2256 | 
             
                        return True
         | 
| 2257 | 
            -
                    if uri ==  | 
| 2257 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000703'):
         | 
| 2258 2258 | 
             
                        return True
         | 
| 2259 | 
            -
                    if uri ==  | 
| 2259 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000704'):
         | 
| 2260 2260 | 
             
                        return True
         | 
| 2261 | 
            -
                    if uri ==  | 
| 2261 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000705'):
         | 
| 2262 2262 | 
             
                        return True
         | 
| 2263 | 
            -
                    if uri ==  | 
| 2263 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000706'):
         | 
| 2264 2264 | 
             
                        return True
         | 
| 2265 | 
            -
                    if uri ==  | 
| 2265 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000714'):
         | 
| 2266 2266 | 
             
                        return True
         | 
| 2267 | 
            -
                    if uri ==  | 
| 2267 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000715'):
         | 
| 2268 2268 | 
             
                        return True
         | 
| 2269 | 
            -
                    if uri ==  | 
| 2269 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000717'):
         | 
| 2270 2270 | 
             
                        return True
         | 
| 2271 | 
            -
                    if uri ==  | 
| 2271 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000719'):
         | 
| 2272 2272 | 
             
                        return True
         | 
| 2273 | 
            -
                    if uri ==  | 
| 2273 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000724'):
         | 
| 2274 2274 | 
             
                        return True
         | 
| 2275 | 
            -
                    if uri ==  | 
| 2275 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000725'):
         | 
| 2276 2276 | 
             
                        return True
         | 
| 2277 | 
            -
                    if uri ==  | 
| 2277 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000727'):
         | 
| 2278 2278 | 
             
                        return True
         | 
| 2279 | 
            -
                    if uri ==  | 
| 2279 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000730'):
         | 
| 2280 2280 | 
             
                        return True
         | 
| 2281 | 
            -
                    if uri ==  | 
| 2281 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000752'):
         | 
| 2282 2282 | 
             
                        return True
         | 
| 2283 | 
            -
                    if uri ==  | 
| 2283 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000753'):
         | 
| 2284 2284 | 
             
                        return True
         | 
| 2285 | 
            -
                    if uri ==  | 
| 2285 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000777'):
         | 
| 2286 2286 | 
             
                        return True
         | 
| 2287 | 
            -
                    if uri ==  | 
| 2287 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000778'):
         | 
| 2288 2288 | 
             
                        return True
         | 
| 2289 | 
            -
                    if uri ==  | 
| 2289 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000830'):
         | 
| 2290 2290 | 
             
                        return True
         | 
| 2291 | 
            -
                    if uri ==  | 
| 2291 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000831'):
         | 
| 2292 2292 | 
             
                        return True
         | 
| 2293 | 
            -
                    if uri ==  | 
| 2293 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000833'):
         | 
| 2294 2294 | 
             
                        return True
         | 
| 2295 | 
            -
                    if uri ==  | 
| 2295 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000834'):
         | 
| 2296 2296 | 
             
                        return True
         | 
| 2297 | 
            -
                    if uri ==  | 
| 2297 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000835'):
         | 
| 2298 2298 | 
             
                        return True
         | 
| 2299 | 
            -
                    if uri ==  | 
| 2299 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000836'):
         | 
| 2300 2300 | 
             
                        return True
         | 
| 2301 | 
            -
                    if uri ==  | 
| 2301 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000837'):
         | 
| 2302 2302 | 
             
                        return True
         | 
| 2303 | 
            -
                    if uri ==  | 
| 2303 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000839'):
         | 
| 2304 2304 | 
             
                        return True
         | 
| 2305 | 
            -
                    if uri ==  | 
| 2305 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000841'):
         | 
| 2306 2306 | 
             
                        return True
         | 
| 2307 | 
            -
                    if uri ==  | 
| 2307 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000842'):
         | 
| 2308 2308 | 
             
                        return True
         | 
| 2309 | 
            -
                    if uri ==  | 
| 2309 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000851'):
         | 
| 2310 2310 | 
             
                        return True
         | 
| 2311 | 
            -
                    if uri ==  | 
| 2311 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0000852'):
         | 
| 2312 2312 | 
             
                        return True
         | 
| 2313 | 
            -
                    if uri ==  | 
| 2313 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001000'):
         | 
| 2314 2314 | 
             
                        return True
         | 
| 2315 | 
            -
                    if uri ==  | 
| 2315 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001001'):
         | 
| 2316 2316 | 
             
                        return True
         | 
| 2317 | 
            -
                    if uri ==  | 
| 2317 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001002'):
         | 
| 2318 2318 | 
             
                        return True
         | 
| 2319 | 
            -
                    if uri ==  | 
| 2319 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001019'):
         | 
| 2320 2320 | 
             
                        return True
         | 
| 2321 | 
            -
                    if uri ==  | 
| 2321 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001037'):
         | 
| 2322 2322 | 
             
                        return True
         | 
| 2323 | 
            -
                    if uri ==  | 
| 2323 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001039'):
         | 
| 2324 2324 | 
             
                        return True
         | 
| 2325 | 
            -
                    if uri ==  | 
| 2325 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001055'):
         | 
| 2326 2326 | 
             
                        return True
         | 
| 2327 | 
            -
                    if uri ==  | 
| 2327 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001056'):
         | 
| 2328 2328 | 
             
                        return True
         | 
| 2329 | 
            -
                    if uri ==  | 
| 2329 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001059'):
         | 
| 2330 2330 | 
             
                        return True
         | 
| 2331 | 
            -
                    if uri ==  | 
| 2331 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001063'):
         | 
| 2332 2332 | 
             
                        return True
         | 
| 2333 | 
            -
                    if uri ==  | 
| 2333 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001214'):
         | 
| 2334 2334 | 
             
                        return True
         | 
| 2335 | 
            -
                    if uri ==  | 
| 2335 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001215'):
         | 
| 2336 2336 | 
             
                        return True
         | 
| 2337 | 
            -
                    if uri ==  | 
| 2337 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001235'):
         | 
| 2338 2338 | 
             
                        return True
         | 
| 2339 | 
            -
                    if uri ==  | 
| 2339 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001236'):
         | 
| 2340 2340 | 
             
                        return True
         | 
| 2341 | 
            -
                    if uri ==  | 
| 2341 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001248'):
         | 
| 2342 2342 | 
             
                        return True
         | 
| 2343 | 
            -
                    if uri ==  | 
| 2343 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001409'):
         | 
| 2344 2344 | 
             
                        return True
         | 
| 2345 | 
            -
                    if uri ==  | 
| 2345 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001410'):
         | 
| 2346 2346 | 
             
                        return True
         | 
| 2347 | 
            -
                    if uri ==  | 
| 2347 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001411'):
         | 
| 2348 2348 | 
             
                        return True
         | 
| 2349 | 
            -
                    if uri ==  | 
| 2349 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001412'):
         | 
| 2350 2350 | 
             
                        return True
         | 
| 2351 | 
            -
                    if uri ==  | 
| 2351 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001419'):
         | 
| 2352 2352 | 
             
                        return True
         | 
| 2353 | 
            -
                    if uri ==  | 
| 2353 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001420'):
         | 
| 2354 2354 | 
             
                        return True
         | 
| 2355 | 
            -
                    if uri ==  | 
| 2355 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001483'):
         | 
| 2356 2356 | 
             
                        return True
         | 
| 2357 | 
            -
                    if uri ==  | 
| 2357 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001527'):
         | 
| 2358 2358 | 
             
                        return True
         | 
| 2359 | 
            -
                    if uri ==  | 
| 2359 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001647'):
         | 
| 2360 2360 | 
             
                        return True
         | 
| 2361 | 
            -
                    if uri ==  | 
| 2361 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001654'):
         | 
| 2362 2362 | 
             
                        return True
         | 
| 2363 | 
            -
                    if uri ==  | 
| 2363 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001679'):
         | 
| 2364 2364 | 
             
                        return True
         | 
| 2365 | 
            -
                    if uri ==  | 
| 2365 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001683'):
         | 
| 2366 2366 | 
             
                        return True
         | 
| 2367 | 
            -
                    if uri ==  | 
| 2367 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001720'):
         | 
| 2368 2368 | 
             
                        return True
         | 
| 2369 | 
            -
                    if uri ==  | 
| 2369 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0001790'):
         | 
| 2370 2370 | 
             
                        return True
         | 
| 2371 | 
            -
                    if uri ==  | 
| 2371 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0005836'):
         | 
| 2372 2372 | 
             
                        return True
         | 
| 2373 | 
            -
                    if uri ==  | 
| 2373 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0005855'):
         | 
| 2374 2374 | 
             
                        return True
         | 
| 2375 | 
            -
                    if uri ==  | 
| 2375 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_0100011'):
         | 
| 2376 2376 | 
             
                        return True
         | 
| 2377 | 
            -
                    if uri ==  | 
| 2377 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_1000002'):
         | 
| 2378 2378 | 
             
                        return True
         | 
| 2379 | 
            -
                    if uri ==  | 
| 2379 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_1000005'):
         | 
| 2380 2380 | 
             
                        return True
         | 
| 2381 | 
            -
                    if uri ==  | 
| 2381 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_1000008'):
         | 
| 2382 2382 | 
             
                        return True
         | 
| 2383 | 
            -
                    if uri ==  | 
| 2383 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_1000036'):
         | 
| 2384 2384 | 
             
                        return True
         | 
| 2385 | 
            -
                    if uri ==  | 
| 2385 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_1001284'):
         | 
| 2386 2386 | 
             
                        return True
         | 
| 2387 | 
            -
                    if uri ==  | 
| 2387 | 
            +
                    if uri == _namespace_SOFA('http://purl.obolibrary.org/obo/SO_2000061'):
         | 
| 2388 2388 | 
             
                        return True
         | 
| 2389 2389 | 
             
                    return False
         | 
| 2390 2390 |  | 
| @@ -2418,5 +2418,5 @@ class SOFO: | |
| 2418 2418 | 
             
                        return cls.has_parent(cls.__parent_properties[uri], parent)
         | 
| 2419 2419 | 
             
                    return False
         | 
| 2420 2420 |  | 
| 2421 | 
            -
                __parent_properties = { _namespace_SOFO('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:complete_evidence_for_feature') : _namespace_SOFO('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:evidence_for_feature') , _namespace_SOFO('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_integral_part') : _namespace_SOFO('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:has_part') , _namespace_SOFO('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:homologous_to') : _namespace_SOFO('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:similar_to') , _namespace_SOFO('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:integral_part_of') : _namespace_SOFO('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:part_of') , _namespace_SOFO('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:member_of') : _namespace_SOFO('http://purl.obolibrary.org/obo/http_//purl.org/obo/owl:part_of') , 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