bio 1.2.1 → 1.3.0
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- data/ChangeLog +3421 -0
- data/KNOWN_ISSUES.rdoc +88 -0
- data/README.rdoc +252 -0
- data/README_DEV.rdoc +285 -0
- data/Rakefile +143 -0
- data/bin/bioruby +0 -0
- data/bin/br_biofetch.rb +0 -0
- data/bin/br_bioflat.rb +12 -1
- data/bin/br_biogetseq.rb +0 -0
- data/bin/br_pmfetch.rb +4 -3
- data/bioruby.gemspec +477 -0
- data/bioruby.gemspec.erb +117 -0
- data/doc/Changes-0.7.rd +7 -0
- data/doc/Changes-1.3.rdoc +239 -0
- data/doc/Tutorial.rd +296 -184
- data/doc/Tutorial.rd.html +1031 -0
- data/doc/Tutorial.rd.ja +111 -45
- data/doc/Tutorial.rd.ja.html +2225 -0
- data/doc/bioruby.css +281 -0
- data/extconf.rb +2 -0
- data/lib/bio.rb +29 -4
- data/lib/bio/appl/blast.rb +306 -121
- data/lib/bio/appl/blast/ddbj.rb +142 -0
- data/lib/bio/appl/blast/format0.rb +35 -25
- data/lib/bio/appl/blast/format8.rb +2 -2
- data/lib/bio/appl/blast/genomenet.rb +263 -0
- data/lib/bio/appl/blast/ncbioptions.rb +220 -0
- data/lib/bio/appl/blast/remote.rb +106 -0
- data/lib/bio/appl/blast/report.rb +260 -9
- data/lib/bio/appl/blast/rexml.rb +12 -5
- data/lib/bio/appl/blast/rpsblast.rb +277 -0
- data/lib/bio/appl/blast/wublast.rb +133 -12
- data/lib/bio/appl/blast/xmlparser.rb +35 -18
- data/lib/bio/appl/blat/report.rb +46 -5
- data/lib/bio/appl/emboss.rb +62 -13
- data/lib/bio/appl/fasta.rb +9 -11
- data/lib/bio/appl/genscan/report.rb +3 -3
- data/lib/bio/appl/hmmer.rb +1 -1
- data/lib/bio/appl/hmmer/report.rb +10 -10
- data/lib/bio/appl/paml/baseml.rb +95 -0
- data/lib/bio/appl/paml/baseml/report.rb +32 -0
- data/lib/bio/appl/paml/codeml.rb +242 -0
- data/lib/bio/appl/paml/codeml/rates.rb +67 -0
- data/lib/bio/appl/paml/codeml/report.rb +67 -0
- data/lib/bio/appl/paml/common.rb +348 -0
- data/lib/bio/appl/paml/common_report.rb +38 -0
- data/lib/bio/appl/paml/yn00.rb +103 -0
- data/lib/bio/appl/paml/yn00/report.rb +32 -0
- data/lib/bio/appl/psort.rb +2 -2
- data/lib/bio/appl/pts1.rb +5 -5
- data/lib/bio/appl/tmhmm/report.rb +10 -1
- data/lib/bio/command.rb +297 -41
- data/lib/bio/compat/features.rb +157 -0
- data/lib/bio/compat/references.rb +128 -0
- data/lib/bio/db/biosql/biosql_to_biosequence.rb +67 -0
- data/lib/bio/db/biosql/sequence.rb +508 -0
- data/lib/bio/db/embl/common.rb +28 -12
- data/lib/bio/db/embl/embl.rb +107 -9
- data/lib/bio/db/embl/embl_to_biosequence.rb +85 -0
- data/lib/bio/db/embl/format_embl.rb +190 -0
- data/lib/bio/db/embl/sptr.rb +15 -16
- data/lib/bio/db/fantom.rb +6 -8
- data/lib/bio/db/fasta.rb +10 -507
- data/lib/bio/db/fasta/defline.rb +532 -0
- data/lib/bio/db/fasta/fasta_to_biosequence.rb +63 -0
- data/lib/bio/db/fasta/format_fasta.rb +97 -0
- data/lib/bio/db/genbank/common.rb +25 -8
- data/lib/bio/db/genbank/format_genbank.rb +187 -0
- data/lib/bio/db/genbank/genbank.rb +36 -1
- data/lib/bio/db/genbank/genbank_to_biosequence.rb +86 -0
- data/lib/bio/db/gff.rb +1791 -119
- data/lib/bio/db/kegg/glycan.rb +2 -6
- data/lib/bio/db/lasergene.rb +3 -3
- data/lib/bio/db/medline.rb +4 -1
- data/lib/bio/db/newick.rb +10 -10
- data/lib/bio/db/pdb/chain.rb +6 -2
- data/lib/bio/db/pdb/pdb.rb +12 -3
- data/lib/bio/db/rebase.rb +7 -8
- data/lib/bio/db/soft.rb +3 -3
- data/lib/bio/feature.rb +1 -88
- data/lib/bio/io/biosql/biodatabase.rb +64 -0
- data/lib/bio/io/biosql/bioentry.rb +29 -0
- data/lib/bio/io/biosql/bioentry_dbxref.rb +11 -0
- data/lib/bio/io/biosql/bioentry_path.rb +12 -0
- data/lib/bio/io/biosql/bioentry_qualifier_value.rb +10 -0
- data/lib/bio/io/biosql/bioentry_reference.rb +10 -0
- data/lib/bio/io/biosql/bioentry_relationship.rb +10 -0
- data/lib/bio/io/biosql/biosequence.rb +11 -0
- data/lib/bio/io/biosql/comment.rb +7 -0
- data/lib/bio/io/biosql/config/database.yml +20 -0
- data/lib/bio/io/biosql/dbxref.rb +13 -0
- data/lib/bio/io/biosql/dbxref_qualifier_value.rb +12 -0
- data/lib/bio/io/biosql/location.rb +32 -0
- data/lib/bio/io/biosql/location_qualifier_value.rb +11 -0
- data/lib/bio/io/biosql/ontology.rb +10 -0
- data/lib/bio/io/biosql/reference.rb +9 -0
- data/lib/bio/io/biosql/seqfeature.rb +32 -0
- data/lib/bio/io/biosql/seqfeature_dbxref.rb +11 -0
- data/lib/bio/io/biosql/seqfeature_path.rb +11 -0
- data/lib/bio/io/biosql/seqfeature_qualifier_value.rb +20 -0
- data/lib/bio/io/biosql/seqfeature_relationship.rb +11 -0
- data/lib/bio/io/biosql/taxon.rb +12 -0
- data/lib/bio/io/biosql/taxon_name.rb +9 -0
- data/lib/bio/io/biosql/term.rb +27 -0
- data/lib/bio/io/biosql/term_dbxref.rb +11 -0
- data/lib/bio/io/biosql/term_path.rb +12 -0
- data/lib/bio/io/biosql/term_relationship.rb +13 -0
- data/lib/bio/io/biosql/term_relationship_term.rb +11 -0
- data/lib/bio/io/biosql/term_synonym.rb +10 -0
- data/lib/bio/io/das.rb +7 -7
- data/lib/bio/io/ddbjxml.rb +57 -0
- data/lib/bio/io/ensembl.rb +2 -2
- data/lib/bio/io/fetch.rb +28 -14
- data/lib/bio/io/flatfile.rb +17 -853
- data/lib/bio/io/flatfile/autodetection.rb +545 -0
- data/lib/bio/io/flatfile/buffer.rb +237 -0
- data/lib/bio/io/flatfile/index.rb +17 -7
- data/lib/bio/io/flatfile/indexer.rb +30 -12
- data/lib/bio/io/flatfile/splitter.rb +297 -0
- data/lib/bio/io/hinv.rb +442 -0
- data/lib/bio/io/keggapi.rb +2 -2
- data/lib/bio/io/ncbirest.rb +733 -0
- data/lib/bio/io/pubmed.rb +34 -80
- data/lib/bio/io/registry.rb +2 -2
- data/lib/bio/io/sql.rb +178 -357
- data/lib/bio/io/togows.rb +458 -0
- data/lib/bio/location.rb +106 -11
- data/lib/bio/pathway.rb +120 -14
- data/lib/bio/reference.rb +115 -101
- data/lib/bio/sequence.rb +164 -183
- data/lib/bio/sequence/adapter.rb +108 -0
- data/lib/bio/sequence/common.rb +22 -45
- data/lib/bio/sequence/compat.rb +2 -2
- data/lib/bio/sequence/dblink.rb +54 -0
- data/lib/bio/sequence/format.rb +254 -77
- data/lib/bio/sequence/format_raw.rb +23 -0
- data/lib/bio/shell.rb +3 -1
- data/lib/bio/shell/core.rb +2 -2
- data/lib/bio/shell/plugin/entry.rb +33 -4
- data/lib/bio/shell/plugin/ncbirest.rb +64 -0
- data/lib/bio/shell/plugin/togows.rb +40 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/bioruby_generator.rb +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/_classes.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/_log.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/_methods.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/_modules.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/_variables.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/bioruby-bg.gif +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/bioruby-gem.png +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/bioruby-link.gif +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/bioruby.css +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/bioruby.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/bioruby_controller.rb +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/bioruby_helper.rb +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/commands.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/history.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/index.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/spinner.gif +0 -0
- data/lib/bio/tree.rb +4 -2
- data/lib/bio/util/color_scheme.rb +2 -2
- data/lib/bio/util/contingency_table.rb +2 -2
- data/lib/bio/util/restriction_enzyme.rb +2 -2
- data/lib/bio/util/restriction_enzyme/single_strand.rb +6 -5
- data/lib/bio/version.rb +25 -0
- data/rdoc.zsh +8 -0
- data/sample/any2fasta.rb +0 -0
- data/sample/biofetch.rb +0 -0
- data/sample/dbget +0 -0
- data/sample/demo_sequence.rb +158 -0
- data/sample/enzymes.rb +0 -0
- data/sample/fasta2tab.rb +0 -0
- data/sample/fastagrep.rb +72 -0
- data/sample/fastasort.rb +54 -0
- data/sample/fsplit.rb +0 -0
- data/sample/gb2fasta.rb +2 -3
- data/sample/gb2tab.rb +0 -0
- data/sample/gbtab2mysql.rb +0 -0
- data/sample/genes2nuc.rb +0 -0
- data/sample/genes2pep.rb +0 -0
- data/sample/genes2tab.rb +0 -0
- data/sample/genome2rb.rb +0 -0
- data/sample/genome2tab.rb +0 -0
- data/sample/goslim.rb +0 -0
- data/sample/gt2fasta.rb +0 -0
- data/sample/na2aa.rb +34 -0
- data/sample/pmfetch.rb +0 -0
- data/sample/pmsearch.rb +0 -0
- data/sample/ssearch2tab.rb +0 -0
- data/sample/tfastx2tab.rb +0 -0
- data/sample/vs-genes.rb +0 -0
- data/setup.rb +1596 -0
- data/test/data/blast/blastp-multi.m7 +188 -0
- data/test/data/command/echoarg2.bat +1 -0
- data/test/data/paml/codeml/control_file.txt +30 -0
- data/test/data/paml/codeml/output.txt +78 -0
- data/test/data/paml/codeml/rates +217 -0
- data/test/data/rpsblast/misc.rpsblast +193 -0
- data/test/data/soft/GDS100_partial.soft +0 -0
- data/test/data/soft/GSE3457_family_partial.soft +0 -0
- data/test/functional/bio/appl/test_pts1.rb +115 -0
- data/test/functional/bio/io/test_ensembl.rb +123 -80
- data/test/functional/bio/io/test_togows.rb +267 -0
- data/test/functional/bio/sequence/test_output_embl.rb +51 -0
- data/test/functional/bio/test_command.rb +301 -0
- data/test/runner.rb +17 -1
- data/test/unit/bio/appl/blast/test_ncbioptions.rb +112 -0
- data/test/unit/bio/appl/blast/test_report.rb +753 -35
- data/test/unit/bio/appl/blast/test_rpsblast.rb +398 -0
- data/test/unit/bio/appl/paml/codeml/test_rates.rb +45 -0
- data/test/unit/bio/appl/paml/codeml/test_report.rb +45 -0
- data/test/unit/bio/appl/paml/test_codeml.rb +174 -0
- data/test/unit/bio/appl/test_blast.rb +135 -4
- data/test/unit/bio/appl/test_fasta.rb +2 -2
- data/test/unit/bio/appl/test_pts1.rb +1 -64
- data/test/unit/bio/db/embl/test_common.rb +15 -15
- data/test/unit/bio/db/embl/test_embl.rb +4 -4
- data/test/unit/bio/db/embl/test_embl_rel89.rb +5 -5
- data/test/unit/bio/db/embl/test_embl_to_bioseq.rb +203 -0
- data/test/unit/bio/db/embl/test_sptr.rb +38 -1
- data/test/unit/bio/db/pdb/test_pdb.rb +2 -2
- data/test/unit/bio/db/test_gff.rb +1151 -25
- data/test/unit/bio/db/test_medline.rb +127 -0
- data/test/unit/bio/db/test_nexus.rb +5 -1
- data/test/unit/bio/db/test_prosite.rb +4 -4
- data/test/unit/bio/io/flatfile/test_autodetection.rb +375 -0
- data/test/unit/bio/io/flatfile/test_buffer.rb +251 -0
- data/test/unit/bio/io/flatfile/test_splitter.rb +369 -0
- data/test/unit/bio/io/test_ddbjxml.rb +8 -3
- data/test/unit/bio/io/test_fastacmd.rb +5 -5
- data/test/unit/bio/io/test_flatfile.rb +357 -106
- data/test/unit/bio/io/test_soapwsdl.rb +2 -2
- data/test/unit/bio/io/test_togows.rb +161 -0
- data/test/unit/bio/sequence/test_common.rb +210 -11
- data/test/unit/bio/sequence/test_compat.rb +3 -3
- data/test/unit/bio/sequence/test_dblink.rb +58 -0
- data/test/unit/bio/sequence/test_na.rb +2 -2
- data/test/unit/bio/test_command.rb +111 -50
- data/test/unit/bio/test_feature.rb +29 -1
- data/test/unit/bio/test_location.rb +566 -6
- data/test/unit/bio/test_pathway.rb +91 -65
- data/test/unit/bio/test_reference.rb +67 -13
- data/test/unit/bio/util/restriction_enzyme/analysis/test_calculated_cuts.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/analysis/test_cut_ranges.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/analysis/test_sequence_range.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_aligned_strands.rb +4 -3
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair_in_enzyme_notation.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations_in_enzyme_notation.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/single_strand/test_cut_locations_in_enzyme_notation.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/test_analysis.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/test_cut_symbol.rb +4 -4
- data/test/unit/bio/util/restriction_enzyme/test_double_stranded.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/test_single_strand.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/test_single_strand_complement.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/test_string_formatting.rb +3 -3
- data/test/unit/bio/util/test_restriction_enzyme.rb +3 -3
- metadata +202 -167
- data/test/unit/bio/appl/blast/test_xmlparser.rb +0 -388
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# Copytight:: Copyright (C) 2005 Mitsuteru Nakao <n@bioruby.org>
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# License:: The Ruby License
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# $Id:$
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require 'pathname'
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methods = ['list_methods','wsdl', 'wsdl=', 'log', 'log=']
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end
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#
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# test/unit/bio/io/test_togows.rb - Unit test for Bio::TogoWS
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# Copyright:: Copyright (C) 2009
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# Naohisa Goto <ng@bioruby.org>
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# License:: The Ruby License
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#
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# $Id:$
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#
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require 'pathname'
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libpath = Pathname.new(File.join(File.dirname(__FILE__), ['..'] * 4, 'lib')).cleanpath.to_s
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require 'uri'
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require 'net/http'
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require 'bio/io/togows'
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require 'test/unit'
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module Bio
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# unit test for Bio::TogoWS::REST
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class TestTogoWSREST < Test::Unit::TestCase
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def setup
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@togows = Bio::TogoWS::REST.new
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end
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def test_debug_default
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assert_equal(false, @togows.debug)
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end
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def test_debug
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assert_equal(true, @togows.debug = true)
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assert_equal(true, @togows.debug)
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assert_equal(false, @togows.debug = false)
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assert_equal(false, @togows.debug)
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assert_equal(true, @togows.debug = true)
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assert_equal(true, @togows.debug)
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end
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def test_internal_http
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assert_kind_of(Net::HTTP, @togows.internal_http)
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end
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end #class TestTogoWSREST
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# unit test for Bio::TogoWS::REST private methods
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class TestTogoWSRESTprivate < Test::Unit::TestCase
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def setup
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@togows = Bio::TogoWS::REST.new
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end
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def test_make_path
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a_and_q = {
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'/ab/cde/fghi' => [ 'ab', 'cde', 'fghi' ],
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'/a+b/a%2Bb/a%2Fb/a%26b/a%3Bb/a%2Cb/a%3Bb' =>
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[ 'a b', 'a+b', 'a/b', 'a&b', 'a;b', 'a,b', 'a;b' ]
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}
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count = 0
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a_and_q.each do |k,v|
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assert_equal(k, @togows.instance_eval { make_path(v) })
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count += 1
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end
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assert_equal(a_and_q.size, count)
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end
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def test_prepare_return_value
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dummyclass = Struct.new(:code, :body)
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dummy200 = dummyclass.new("200", "this is test")
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assert_equal("this is test",
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@togows.instance_eval { prepare_return_value(dummy200) })
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dummy404 = dummyclass.new("404", "not found")
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assert_equal(nil,
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@togows.instance_eval { prepare_return_value(dummy404) })
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end
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end #class TestTogoWSRESTprivate
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# unit test for Bio::TogoWS::REST class methods
|
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class TestTogoWSRESTclassMethod < Test::Unit::TestCase
|
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+
|
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def test_new
|
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+
assert_instance_of(Bio::TogoWS::REST, Bio::TogoWS::REST.new)
|
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|
+
end
|
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+
|
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|
+
def test_new_with_uri_string
|
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|
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t = Bio::TogoWS::REST.new('http://localhost:1234/test')
|
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assert_instance_of(Bio::TogoWS::REST, t)
|
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http = t.internal_http
|
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assert_equal('localhost', http.address)
|
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assert_equal(1234, http.port)
|
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|
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assert_equal('/test/', t.instance_eval { @pathbase })
|
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|
+
end
|
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def test_new_with_uri_object
|
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u = URI.parse('http://localhost:1234/test')
|
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t = Bio::TogoWS::REST.new(u)
|
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assert_instance_of(Bio::TogoWS::REST, t)
|
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http = t.internal_http
|
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assert_equal('localhost', http.address)
|
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assert_equal(1234, http.port)
|
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assert_equal('/test/', t.instance_eval { @pathbase })
|
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|
+
end
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def test_entry
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assert_respond_to(Bio::TogoWS::REST, :entry)
|
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|
+
end
|
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+
|
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def test_search
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assert_respond_to(Bio::TogoWS::REST, :search)
|
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+
end
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def test_convert
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assert_respond_to(Bio::TogoWS::REST, :convert)
|
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+
end
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def test_retrieve
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assert_respond_to(Bio::TogoWS::REST, :retrieve)
|
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end
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+
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def test_entry_database_list
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assert_respond_to(Bio::TogoWS::REST, :entry_database_list)
|
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end
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def test_search_database_list
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assert_respond_to(Bio::TogoWS::REST, :search_database_list)
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end
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end #class TestTogoWSRESTclassMethod
|
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# dummy class for testing Bio::TogoWS::AccessWait
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class DummyAccessWait
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include Bio::TogoWS::AccessWait
|
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|
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end
|
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# unit test for Bio::TogoWS::AccessWait (all methods are private)
|
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class TestTogoWSAccessWait < Test::Unit::TestCase
|
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def setup
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@obj = DummyAccessWait.new
|
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end
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def test_togows_access_wait
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assert_kind_of(Numeric, @obj.instance_eval { togows_access_wait })
|
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|
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waits = 0
|
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2.times { waits += @obj.instance_eval { togows_access_wait } }
|
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assert(waits > 0)
|
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|
+
end
|
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+
|
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|
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def test_reset_togows_access_wait
|
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assert_nothing_raised {
|
156
|
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@obj.instance_eval { reset_togows_access_wait }
|
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|
+
}
|
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|
+
end
|
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|
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end #class TestTogoWSAccessWait
|
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|
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|
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end #module Bio
|
@@ -1,10 +1,12 @@
|
|
1
1
|
#
|
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2
|
# test/unit/bio/sequence/test_common.rb - Unit test for Bio::Sequencce::Common
|
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3
|
#
|
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|
-
# Copyright:: Copyright (C) 2006
|
4
|
+
# Copyright:: Copyright (C) 2006-2008
|
5
|
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# Mitsuteru C. Nakao <n@bioruby.org>,
|
6
|
+
# Naohisa Goto <ng@bioruby.org>
|
5
7
|
# License:: The Ruby License
|
6
8
|
#
|
7
|
-
# $Id
|
9
|
+
# $Id:$
|
8
10
|
#
|
9
11
|
|
10
12
|
require 'pathname'
|
@@ -15,7 +17,7 @@ require 'test/unit'
|
|
15
17
|
require 'bio/sequence'
|
16
18
|
require 'bio/sequence/common'
|
17
19
|
|
18
|
-
module Bio
|
20
|
+
module Bio; module TestSequenceCommon
|
19
21
|
|
20
22
|
class TSequence < String
|
21
23
|
include Bio::Sequence::Common
|
@@ -86,13 +88,13 @@ module Bio
|
|
86
88
|
class TestSequenceCommonNormalize < Test::Unit::TestCase
|
87
89
|
def test_no_normalize
|
88
90
|
str = "atgcatgcatgcatgcaaaA"
|
89
|
-
obj =
|
91
|
+
obj = TSequence.new(str)
|
90
92
|
assert_equal("atgcatgcatgcatgcaaaA", obj)
|
91
93
|
end
|
92
94
|
|
93
95
|
def test_normalize_A
|
94
96
|
str = "atgcatgcatgcatgcaaaA"
|
95
|
-
seq =
|
97
|
+
seq = TSequence.new(str)
|
96
98
|
assert_equal("atgcatgcatgcatgcaaaA", seq)
|
97
99
|
obj = seq.normalize!
|
98
100
|
assert_equal("atgcatgcatgcatgcaaaA", obj)
|
@@ -100,7 +102,7 @@ module Bio
|
|
100
102
|
|
101
103
|
def test_normalize_a
|
102
104
|
str = "atgcatgcatgcatgcaaa"
|
103
|
-
seq =
|
105
|
+
seq = TSequence.new(str)
|
104
106
|
assert_equal("atgcatgcatgcatgcaaa", seq)
|
105
107
|
obj = seq.normalize!
|
106
108
|
assert_equal("atgcatgcatgcatgcaaa", obj)
|
@@ -108,16 +110,213 @@ module Bio
|
|
108
110
|
end
|
109
111
|
|
110
112
|
|
111
|
-
class
|
113
|
+
class TestSequenceCommonRandomize < Test::Unit::TestCase
|
112
114
|
|
113
|
-
def
|
114
|
-
|
115
|
+
def setup
|
116
|
+
@str = "attcacgcctgctattcccgtcagcctgagcttgccgcgaagctgatgaaagatgttatc"
|
117
|
+
@seq = TSequence.new(@str)
|
118
|
+
@orig = TSequence.new(@str)
|
115
119
|
end
|
116
120
|
|
121
|
+
# test for Bio::Sequence::Common#randomize(hash = nil)
|
117
122
|
def test_randomize
|
118
|
-
|
123
|
+
rseqs = (0..2).collect { |i| @seq.randomize }
|
124
|
+
|
125
|
+
# not breaking given seq?
|
126
|
+
assert_equal(@orig, @seq)
|
127
|
+
|
128
|
+
# same length?
|
129
|
+
rseqs.each do |rseq|
|
130
|
+
assert_equal(@orig.length, rseq.length)
|
131
|
+
end
|
132
|
+
|
133
|
+
# same composition?
|
134
|
+
[ 'a', 'c', 'g', 't', 'n' ].each do |chr|
|
135
|
+
count = @orig.count(chr)
|
136
|
+
rseqs.each do |rseq|
|
137
|
+
assert_equal(count, rseq.count(chr))
|
138
|
+
end
|
139
|
+
end
|
140
|
+
|
141
|
+
# randomized? (very simple check)
|
142
|
+
assert(rseqs[0] != rseqs[1])
|
143
|
+
assert(rseqs[0] != rseqs[2])
|
144
|
+
assert(rseqs[1] != rseqs[2])
|
145
|
+
end
|
146
|
+
|
147
|
+
# testing Bio::Sequence::Common#randomize() { |x| ... }
|
148
|
+
def test_randomize_with_block
|
149
|
+
composition = Hash.new(0)
|
150
|
+
[ 'a', 'c', 'g', 't' ].each do |chr|
|
151
|
+
composition[chr] = @seq.count(chr)
|
152
|
+
end
|
153
|
+
|
154
|
+
rseqs = (0..2).collect do |i|
|
155
|
+
newcomposition = Hash.new(0)
|
156
|
+
newseq = ''
|
157
|
+
ret = @seq.randomize do |c|
|
158
|
+
assert_kind_of(TSequence, c)
|
159
|
+
newcomposition[c] += 1
|
160
|
+
newseq.concat c
|
161
|
+
end
|
162
|
+
# same length?
|
163
|
+
assert_equal(@orig.length, newseq.length)
|
164
|
+
# same composition?
|
165
|
+
assert_equal(composition, newcomposition)
|
166
|
+
# returned value is empty sequence?
|
167
|
+
assert_equal(TSequence.new(''), ret)
|
168
|
+
# not breaking given seq?
|
169
|
+
assert_equal(@orig, @seq)
|
170
|
+
newseq
|
171
|
+
end
|
172
|
+
|
173
|
+
# randomized? (very simple check)
|
174
|
+
assert(rseqs[0] != rseqs[1])
|
175
|
+
assert(rseqs[0] != rseqs[2])
|
176
|
+
assert(rseqs[1] != rseqs[2])
|
177
|
+
end
|
178
|
+
|
179
|
+
# testing Bio::Sequence::Common#randomize(hash)
|
180
|
+
def test_randomize_with_hash
|
181
|
+
hash = { 'a' => 20, 'c' => 19, 'g' => 18, 't' => 17 }
|
182
|
+
hash.default = 0
|
183
|
+
len = 0
|
184
|
+
hash.each_value { |v| len += v }
|
185
|
+
|
186
|
+
rseqs = (0..2).collect do |i|
|
187
|
+
rseq = @seq.randomize(hash)
|
188
|
+
# same length?
|
189
|
+
assert_equal(len, rseq.length)
|
190
|
+
# same composition?
|
191
|
+
[ 'a', 'c', 'g', 't', 'n' ].each do |chr|
|
192
|
+
assert_equal(hash[chr], rseq.count(chr))
|
193
|
+
end
|
194
|
+
# returned value is instance of TSequence?
|
195
|
+
assert_instance_of(TSequence, rseq)
|
196
|
+
# not breaking given seq?
|
197
|
+
assert_equal(@orig, @seq)
|
198
|
+
rseq
|
199
|
+
end
|
200
|
+
|
201
|
+
# randomized? (very simple check)
|
202
|
+
assert(rseqs[0] != rseqs[1])
|
203
|
+
assert(rseqs[0] != rseqs[2])
|
204
|
+
assert(rseqs[1] != rseqs[2])
|
119
205
|
end
|
120
206
|
|
207
|
+
# testing Bio::Sequence::Common#randomize(hash) { |x| ... }
|
208
|
+
def test_randomize_with_hash_block
|
209
|
+
hash = { 'a' => 20, 'c' => 19, 'g' => 18, 't' => 17 }
|
210
|
+
hash.default = 0
|
211
|
+
len = 0
|
212
|
+
hash.each_value { |v| len += v }
|
213
|
+
|
214
|
+
rseqs = (0..2).collect do |i|
|
215
|
+
newcomposition = Hash.new(0)
|
216
|
+
newseq = ''
|
217
|
+
ret = @seq.randomize(hash) do |c|
|
218
|
+
#assert_kind_of(TSequence, c)
|
219
|
+
assert_kind_of(String, c)
|
220
|
+
newcomposition[c] += 1
|
221
|
+
newseq.concat c
|
222
|
+
end
|
223
|
+
# same length?
|
224
|
+
assert_equal(len, newseq.length)
|
225
|
+
# same composition?
|
226
|
+
assert_equal(hash, newcomposition)
|
227
|
+
# returned value is empty TSequence?
|
228
|
+
assert_equal(TSequence.new(''), ret)
|
229
|
+
# not breaking given seq?
|
230
|
+
assert_equal(@orig, @seq)
|
231
|
+
newseq
|
232
|
+
end
|
233
|
+
|
234
|
+
# randomized? (very simple check)
|
235
|
+
assert(rseqs[0] != rseqs[1])
|
236
|
+
assert(rseqs[0] != rseqs[2])
|
237
|
+
assert(rseqs[1] != rseqs[2])
|
238
|
+
end
|
239
|
+
|
240
|
+
def chi2(hist, f, k)
|
241
|
+
chi2 = 0
|
242
|
+
(0...k).each do |i|
|
243
|
+
chi2 += ((hist[i] - f) ** 2).quo(f)
|
244
|
+
end
|
245
|
+
chi2
|
246
|
+
end
|
247
|
+
private :chi2
|
248
|
+
|
249
|
+
# chi-square test for distribution of chi2 values from
|
250
|
+
# distribution of index('a')
|
251
|
+
def randomize_equiprobability
|
252
|
+
# Reference: http://www.geocities.jp/m_hiroi/light/pystat04.html
|
253
|
+
seq = TSequence.new('ccccgggtta') # length must be 10
|
254
|
+
k = 10
|
255
|
+
hist = Array.new(k, 0)
|
256
|
+
iter = 200
|
257
|
+
# F for index('a')
|
258
|
+
f = iter.quo(seq.length).to_f
|
259
|
+
|
260
|
+
# chi2 distribution, degree of freedom 9
|
261
|
+
# Reference: http://www.geocities.jp/m_hiroi/light/pystat04.html
|
262
|
+
# Reference: http://keisan.casio.jp/has10/SpecExec.cgi
|
263
|
+
# P = 0.9, 0.8, 0.7, ... 0.1, 0
|
264
|
+
chi2_table = [ 14.684, 12.242, 10.656, 9.414, 8.343,
|
265
|
+
7.357, 6.393, 5.380, 4.168, 0.000 ]
|
266
|
+
|
267
|
+
chi2_hist = Array.new(k, 0)
|
268
|
+
chi2_iter = 200
|
269
|
+
chi2_iter.times do
|
270
|
+
hist.fill(0)
|
271
|
+
iter.times { hist[yield(seq).index('a')] += 1 }
|
272
|
+
chi2 = chi2(hist, f, k)
|
273
|
+
idx = (0...(chi2_table.size)).find { |i| chi2 >= chi2_table[i] }
|
274
|
+
chi2_hist[idx] += 1
|
275
|
+
end
|
276
|
+
|
277
|
+
chi2_f = chi2_iter.quo(k).to_f
|
278
|
+
chi2_chi2 = chi2(chi2_hist, chi2_f, k)
|
279
|
+
#$stderr.puts chi2_chi2
|
280
|
+
|
281
|
+
## chi-square test, freedom 9, significance level 5%
|
282
|
+
#assert_operator(16.919, :>, chi2_chi2, "test of chi2 < 16.919 failed (#{chi2_chi2})")
|
283
|
+
# chi-square test, freedom 9, significance level 1%
|
284
|
+
assert_operator(21.666, :>, chi2_chi2, "test of chi2 < 21.666 failed (#{chi2_chi2})")
|
285
|
+
end
|
286
|
+
private :randomize_equiprobability
|
287
|
+
|
288
|
+
def test_randomize_equiprobability
|
289
|
+
randomize_equiprobability { |seq| seq.randomize }
|
290
|
+
end
|
291
|
+
|
292
|
+
def test_randomize_with_hash_equiprobability
|
293
|
+
hash = { 'c' => 4, 'g' => 3, 't' => 2, 'a' => 1 }
|
294
|
+
randomize_equiprobability { |seq| seq.randomize(hash) }
|
295
|
+
end
|
296
|
+
|
297
|
+
## disabled because it takes too long time.
|
298
|
+
#def test_randomize_with_block_equiprobability
|
299
|
+
# randomize_equiprobability do |seq|
|
300
|
+
# newseq = ''
|
301
|
+
# seq.randomize do |c|
|
302
|
+
# newseq.concat c
|
303
|
+
# end
|
304
|
+
# newseq
|
305
|
+
# end
|
306
|
+
#end
|
307
|
+
|
308
|
+
## disabled because it takes too long time.
|
309
|
+
#def test_randomize_with_hash_block_equiprobability
|
310
|
+
# hash = { 'c' => 4, 'g' => 3, 't' => 2, 'a' => 1 }
|
311
|
+
# randomize_equiprobability do |seq|
|
312
|
+
# newseq = ''
|
313
|
+
# seq.randomize(hash) do |c|
|
314
|
+
# newseq.concat c
|
315
|
+
# end
|
316
|
+
# newseq
|
317
|
+
# end
|
318
|
+
#end
|
319
|
+
|
121
320
|
end
|
122
321
|
|
123
322
|
|
@@ -171,4 +370,4 @@ module Bio
|
|
171
370
|
|
172
371
|
end
|
173
372
|
|
174
|
-
end
|
373
|
+
end; end #module Bio; module TestSequenceCommon
|
@@ -4,7 +4,7 @@
|
|
4
4
|
# Copyright:: Copyright (C) 2006 Mitsuteru C. Nakao <n@bioruby.org>
|
5
5
|
# License:: The Ruby License
|
6
6
|
#
|
7
|
-
# $Id
|
7
|
+
# $Id:$
|
8
8
|
#
|
9
9
|
|
10
10
|
require 'pathname'
|
@@ -15,7 +15,7 @@ require 'test/unit'
|
|
15
15
|
require 'bio/sequence'
|
16
16
|
require 'bio/sequence/compat'
|
17
17
|
|
18
|
-
module Bio
|
18
|
+
module Bio; module TestSequenceCompat
|
19
19
|
|
20
20
|
class TSequence < String
|
21
21
|
include Bio::Sequence::Common
|
@@ -66,4 +66,4 @@ module Bio
|
|
66
66
|
end
|
67
67
|
end
|
68
68
|
|
69
|
-
end
|
69
|
+
end; end #module Bio; module TestSequenceCompat
|