bio 1.2.1 → 1.3.0
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- data/ChangeLog +3421 -0
- data/KNOWN_ISSUES.rdoc +88 -0
- data/README.rdoc +252 -0
- data/README_DEV.rdoc +285 -0
- data/Rakefile +143 -0
- data/bin/bioruby +0 -0
- data/bin/br_biofetch.rb +0 -0
- data/bin/br_bioflat.rb +12 -1
- data/bin/br_biogetseq.rb +0 -0
- data/bin/br_pmfetch.rb +4 -3
- data/bioruby.gemspec +477 -0
- data/bioruby.gemspec.erb +117 -0
- data/doc/Changes-0.7.rd +7 -0
- data/doc/Changes-1.3.rdoc +239 -0
- data/doc/Tutorial.rd +296 -184
- data/doc/Tutorial.rd.html +1031 -0
- data/doc/Tutorial.rd.ja +111 -45
- data/doc/Tutorial.rd.ja.html +2225 -0
- data/doc/bioruby.css +281 -0
- data/extconf.rb +2 -0
- data/lib/bio.rb +29 -4
- data/lib/bio/appl/blast.rb +306 -121
- data/lib/bio/appl/blast/ddbj.rb +142 -0
- data/lib/bio/appl/blast/format0.rb +35 -25
- data/lib/bio/appl/blast/format8.rb +2 -2
- data/lib/bio/appl/blast/genomenet.rb +263 -0
- data/lib/bio/appl/blast/ncbioptions.rb +220 -0
- data/lib/bio/appl/blast/remote.rb +106 -0
- data/lib/bio/appl/blast/report.rb +260 -9
- data/lib/bio/appl/blast/rexml.rb +12 -5
- data/lib/bio/appl/blast/rpsblast.rb +277 -0
- data/lib/bio/appl/blast/wublast.rb +133 -12
- data/lib/bio/appl/blast/xmlparser.rb +35 -18
- data/lib/bio/appl/blat/report.rb +46 -5
- data/lib/bio/appl/emboss.rb +62 -13
- data/lib/bio/appl/fasta.rb +9 -11
- data/lib/bio/appl/genscan/report.rb +3 -3
- data/lib/bio/appl/hmmer.rb +1 -1
- data/lib/bio/appl/hmmer/report.rb +10 -10
- data/lib/bio/appl/paml/baseml.rb +95 -0
- data/lib/bio/appl/paml/baseml/report.rb +32 -0
- data/lib/bio/appl/paml/codeml.rb +242 -0
- data/lib/bio/appl/paml/codeml/rates.rb +67 -0
- data/lib/bio/appl/paml/codeml/report.rb +67 -0
- data/lib/bio/appl/paml/common.rb +348 -0
- data/lib/bio/appl/paml/common_report.rb +38 -0
- data/lib/bio/appl/paml/yn00.rb +103 -0
- data/lib/bio/appl/paml/yn00/report.rb +32 -0
- data/lib/bio/appl/psort.rb +2 -2
- data/lib/bio/appl/pts1.rb +5 -5
- data/lib/bio/appl/tmhmm/report.rb +10 -1
- data/lib/bio/command.rb +297 -41
- data/lib/bio/compat/features.rb +157 -0
- data/lib/bio/compat/references.rb +128 -0
- data/lib/bio/db/biosql/biosql_to_biosequence.rb +67 -0
- data/lib/bio/db/biosql/sequence.rb +508 -0
- data/lib/bio/db/embl/common.rb +28 -12
- data/lib/bio/db/embl/embl.rb +107 -9
- data/lib/bio/db/embl/embl_to_biosequence.rb +85 -0
- data/lib/bio/db/embl/format_embl.rb +190 -0
- data/lib/bio/db/embl/sptr.rb +15 -16
- data/lib/bio/db/fantom.rb +6 -8
- data/lib/bio/db/fasta.rb +10 -507
- data/lib/bio/db/fasta/defline.rb +532 -0
- data/lib/bio/db/fasta/fasta_to_biosequence.rb +63 -0
- data/lib/bio/db/fasta/format_fasta.rb +97 -0
- data/lib/bio/db/genbank/common.rb +25 -8
- data/lib/bio/db/genbank/format_genbank.rb +187 -0
- data/lib/bio/db/genbank/genbank.rb +36 -1
- data/lib/bio/db/genbank/genbank_to_biosequence.rb +86 -0
- data/lib/bio/db/gff.rb +1791 -119
- data/lib/bio/db/kegg/glycan.rb +2 -6
- data/lib/bio/db/lasergene.rb +3 -3
- data/lib/bio/db/medline.rb +4 -1
- data/lib/bio/db/newick.rb +10 -10
- data/lib/bio/db/pdb/chain.rb +6 -2
- data/lib/bio/db/pdb/pdb.rb +12 -3
- data/lib/bio/db/rebase.rb +7 -8
- data/lib/bio/db/soft.rb +3 -3
- data/lib/bio/feature.rb +1 -88
- data/lib/bio/io/biosql/biodatabase.rb +64 -0
- data/lib/bio/io/biosql/bioentry.rb +29 -0
- data/lib/bio/io/biosql/bioentry_dbxref.rb +11 -0
- data/lib/bio/io/biosql/bioentry_path.rb +12 -0
- data/lib/bio/io/biosql/bioentry_qualifier_value.rb +10 -0
- data/lib/bio/io/biosql/bioentry_reference.rb +10 -0
- data/lib/bio/io/biosql/bioentry_relationship.rb +10 -0
- data/lib/bio/io/biosql/biosequence.rb +11 -0
- data/lib/bio/io/biosql/comment.rb +7 -0
- data/lib/bio/io/biosql/config/database.yml +20 -0
- data/lib/bio/io/biosql/dbxref.rb +13 -0
- data/lib/bio/io/biosql/dbxref_qualifier_value.rb +12 -0
- data/lib/bio/io/biosql/location.rb +32 -0
- data/lib/bio/io/biosql/location_qualifier_value.rb +11 -0
- data/lib/bio/io/biosql/ontology.rb +10 -0
- data/lib/bio/io/biosql/reference.rb +9 -0
- data/lib/bio/io/biosql/seqfeature.rb +32 -0
- data/lib/bio/io/biosql/seqfeature_dbxref.rb +11 -0
- data/lib/bio/io/biosql/seqfeature_path.rb +11 -0
- data/lib/bio/io/biosql/seqfeature_qualifier_value.rb +20 -0
- data/lib/bio/io/biosql/seqfeature_relationship.rb +11 -0
- data/lib/bio/io/biosql/taxon.rb +12 -0
- data/lib/bio/io/biosql/taxon_name.rb +9 -0
- data/lib/bio/io/biosql/term.rb +27 -0
- data/lib/bio/io/biosql/term_dbxref.rb +11 -0
- data/lib/bio/io/biosql/term_path.rb +12 -0
- data/lib/bio/io/biosql/term_relationship.rb +13 -0
- data/lib/bio/io/biosql/term_relationship_term.rb +11 -0
- data/lib/bio/io/biosql/term_synonym.rb +10 -0
- data/lib/bio/io/das.rb +7 -7
- data/lib/bio/io/ddbjxml.rb +57 -0
- data/lib/bio/io/ensembl.rb +2 -2
- data/lib/bio/io/fetch.rb +28 -14
- data/lib/bio/io/flatfile.rb +17 -853
- data/lib/bio/io/flatfile/autodetection.rb +545 -0
- data/lib/bio/io/flatfile/buffer.rb +237 -0
- data/lib/bio/io/flatfile/index.rb +17 -7
- data/lib/bio/io/flatfile/indexer.rb +30 -12
- data/lib/bio/io/flatfile/splitter.rb +297 -0
- data/lib/bio/io/hinv.rb +442 -0
- data/lib/bio/io/keggapi.rb +2 -2
- data/lib/bio/io/ncbirest.rb +733 -0
- data/lib/bio/io/pubmed.rb +34 -80
- data/lib/bio/io/registry.rb +2 -2
- data/lib/bio/io/sql.rb +178 -357
- data/lib/bio/io/togows.rb +458 -0
- data/lib/bio/location.rb +106 -11
- data/lib/bio/pathway.rb +120 -14
- data/lib/bio/reference.rb +115 -101
- data/lib/bio/sequence.rb +164 -183
- data/lib/bio/sequence/adapter.rb +108 -0
- data/lib/bio/sequence/common.rb +22 -45
- data/lib/bio/sequence/compat.rb +2 -2
- data/lib/bio/sequence/dblink.rb +54 -0
- data/lib/bio/sequence/format.rb +254 -77
- data/lib/bio/sequence/format_raw.rb +23 -0
- data/lib/bio/shell.rb +3 -1
- data/lib/bio/shell/core.rb +2 -2
- data/lib/bio/shell/plugin/entry.rb +33 -4
- data/lib/bio/shell/plugin/ncbirest.rb +64 -0
- data/lib/bio/shell/plugin/togows.rb +40 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/bioruby_generator.rb +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/_classes.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/_log.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/_methods.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/_modules.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/_variables.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/bioruby-bg.gif +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/bioruby-gem.png +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/bioruby-link.gif +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/bioruby.css +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/bioruby.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/bioruby_controller.rb +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/bioruby_helper.rb +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/commands.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/history.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/index.rhtml +0 -0
- data/lib/bio/shell/rails/vendor/plugins/{generators → bioruby/generators}/bioruby/templates/spinner.gif +0 -0
- data/lib/bio/tree.rb +4 -2
- data/lib/bio/util/color_scheme.rb +2 -2
- data/lib/bio/util/contingency_table.rb +2 -2
- data/lib/bio/util/restriction_enzyme.rb +2 -2
- data/lib/bio/util/restriction_enzyme/single_strand.rb +6 -5
- data/lib/bio/version.rb +25 -0
- data/rdoc.zsh +8 -0
- data/sample/any2fasta.rb +0 -0
- data/sample/biofetch.rb +0 -0
- data/sample/dbget +0 -0
- data/sample/demo_sequence.rb +158 -0
- data/sample/enzymes.rb +0 -0
- data/sample/fasta2tab.rb +0 -0
- data/sample/fastagrep.rb +72 -0
- data/sample/fastasort.rb +54 -0
- data/sample/fsplit.rb +0 -0
- data/sample/gb2fasta.rb +2 -3
- data/sample/gb2tab.rb +0 -0
- data/sample/gbtab2mysql.rb +0 -0
- data/sample/genes2nuc.rb +0 -0
- data/sample/genes2pep.rb +0 -0
- data/sample/genes2tab.rb +0 -0
- data/sample/genome2rb.rb +0 -0
- data/sample/genome2tab.rb +0 -0
- data/sample/goslim.rb +0 -0
- data/sample/gt2fasta.rb +0 -0
- data/sample/na2aa.rb +34 -0
- data/sample/pmfetch.rb +0 -0
- data/sample/pmsearch.rb +0 -0
- data/sample/ssearch2tab.rb +0 -0
- data/sample/tfastx2tab.rb +0 -0
- data/sample/vs-genes.rb +0 -0
- data/setup.rb +1596 -0
- data/test/data/blast/blastp-multi.m7 +188 -0
- data/test/data/command/echoarg2.bat +1 -0
- data/test/data/paml/codeml/control_file.txt +30 -0
- data/test/data/paml/codeml/output.txt +78 -0
- data/test/data/paml/codeml/rates +217 -0
- data/test/data/rpsblast/misc.rpsblast +193 -0
- data/test/data/soft/GDS100_partial.soft +0 -0
- data/test/data/soft/GSE3457_family_partial.soft +0 -0
- data/test/functional/bio/appl/test_pts1.rb +115 -0
- data/test/functional/bio/io/test_ensembl.rb +123 -80
- data/test/functional/bio/io/test_togows.rb +267 -0
- data/test/functional/bio/sequence/test_output_embl.rb +51 -0
- data/test/functional/bio/test_command.rb +301 -0
- data/test/runner.rb +17 -1
- data/test/unit/bio/appl/blast/test_ncbioptions.rb +112 -0
- data/test/unit/bio/appl/blast/test_report.rb +753 -35
- data/test/unit/bio/appl/blast/test_rpsblast.rb +398 -0
- data/test/unit/bio/appl/paml/codeml/test_rates.rb +45 -0
- data/test/unit/bio/appl/paml/codeml/test_report.rb +45 -0
- data/test/unit/bio/appl/paml/test_codeml.rb +174 -0
- data/test/unit/bio/appl/test_blast.rb +135 -4
- data/test/unit/bio/appl/test_fasta.rb +2 -2
- data/test/unit/bio/appl/test_pts1.rb +1 -64
- data/test/unit/bio/db/embl/test_common.rb +15 -15
- data/test/unit/bio/db/embl/test_embl.rb +4 -4
- data/test/unit/bio/db/embl/test_embl_rel89.rb +5 -5
- data/test/unit/bio/db/embl/test_embl_to_bioseq.rb +203 -0
- data/test/unit/bio/db/embl/test_sptr.rb +38 -1
- data/test/unit/bio/db/pdb/test_pdb.rb +2 -2
- data/test/unit/bio/db/test_gff.rb +1151 -25
- data/test/unit/bio/db/test_medline.rb +127 -0
- data/test/unit/bio/db/test_nexus.rb +5 -1
- data/test/unit/bio/db/test_prosite.rb +4 -4
- data/test/unit/bio/io/flatfile/test_autodetection.rb +375 -0
- data/test/unit/bio/io/flatfile/test_buffer.rb +251 -0
- data/test/unit/bio/io/flatfile/test_splitter.rb +369 -0
- data/test/unit/bio/io/test_ddbjxml.rb +8 -3
- data/test/unit/bio/io/test_fastacmd.rb +5 -5
- data/test/unit/bio/io/test_flatfile.rb +357 -106
- data/test/unit/bio/io/test_soapwsdl.rb +2 -2
- data/test/unit/bio/io/test_togows.rb +161 -0
- data/test/unit/bio/sequence/test_common.rb +210 -11
- data/test/unit/bio/sequence/test_compat.rb +3 -3
- data/test/unit/bio/sequence/test_dblink.rb +58 -0
- data/test/unit/bio/sequence/test_na.rb +2 -2
- data/test/unit/bio/test_command.rb +111 -50
- data/test/unit/bio/test_feature.rb +29 -1
- data/test/unit/bio/test_location.rb +566 -6
- data/test/unit/bio/test_pathway.rb +91 -65
- data/test/unit/bio/test_reference.rb +67 -13
- data/test/unit/bio/util/restriction_enzyme/analysis/test_calculated_cuts.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/analysis/test_cut_ranges.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/analysis/test_sequence_range.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_aligned_strands.rb +4 -3
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_location_pair_in_enzyme_notation.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/double_stranded/test_cut_locations_in_enzyme_notation.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/single_strand/test_cut_locations_in_enzyme_notation.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/test_analysis.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/test_cut_symbol.rb +4 -4
- data/test/unit/bio/util/restriction_enzyme/test_double_stranded.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/test_single_strand.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/test_single_strand_complement.rb +3 -3
- data/test/unit/bio/util/restriction_enzyme/test_string_formatting.rb +3 -3
- data/test/unit/bio/util/test_restriction_enzyme.rb +3 -3
- metadata +202 -167
- data/test/unit/bio/appl/blast/test_xmlparser.rb +0 -388
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# = bio/db/fasta/defline.rb - FASTA defline parser class
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#
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# Copyright:: Copyright (C) 2001, 2002
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# GOTO Naohisa <ngoto@gen-info.osaka-u.ac.jp>,
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# Toshiaki Katayama <k@bioruby.org>
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# License:: The Ruby License
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#
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# $Id: defline.rb,v 1.1.2.1 2008/06/20 13:22:32 ngoto Exp $
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#
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# == Description
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#
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# Bio::FastaDefline is a parser class for definition line (defline)
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# of the FASTA format.
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#
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# == Examples
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#
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# rub = Bio::FastaDefline.new('>gi|671595|emb|CAA85678.1| rubisco large subunit [Perovskia abrotanoides]')
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# rub.entry_id ==> 'gi|671595'
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# rub.get('emb') ==> 'CAA85678.1'
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# rub.emb ==> 'CAA85678.1'
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# rub.gi ==> '671595'
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# rub.accession ==> 'CAA85678'
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# rub.accessions ==> [ 'CAA85678' ]
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# rub.acc_version ==> 'CAA85678.1'
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# rub.list_ids ==> [["gi", "671595"],
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# ["emb", "CAA85678.1", nil],
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# ["Perovskia abrotanoides"]]
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#
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# ckr = Bio::FastaDefline.new(">gi|2495000|sp|Q63931|CCKR_CAVPO CHOLECYSTOKININ TYPE A RECEPTOR (CCK-A RECEPTOR) (CCK-AR)\001gi|2147182|pir||I51898 cholecystokinin A receptor - guinea pig\001gi|544724|gb|AAB29504.1| cholecystokinin A receptor; CCK-A receptor [Cavia]")
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# ckr.entry_id ==> "gi|2495000"
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# ckr.sp ==> "CCKR_CAVPO"
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# ckr.pir ==> "I51898"
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# ckr.gb ==> "AAB29504.1"
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# ckr.gi ==> "2495000"
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# ckr.accession ==> "AAB29504"
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# ckr.accessions ==> ["Q63931", "AAB29504"]
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# ckr.acc_version ==> "AAB29504.1"
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# ckr.locus ==> nil
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# ckr.description ==>
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# "CHOLECYSTOKININ TYPE A RECEPTOR (CCK-A RECEPTOR) (CCK-AR)"
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# ckr.descriptions ==>
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# ["CHOLECYSTOKININ TYPE A RECEPTOR (CCK-A RECEPTOR) (CCK-AR)",
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# "cholecystokinin A receptor - guinea pig",
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# "cholecystokinin A receptor; CCK-A receptor [Cavia]"]
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# ckr.words ==>
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# ["cavia", "cck-a", "cck-ar", "cholecystokinin", "guinea", "pig",
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# "receptor", "type"]
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# ckr.id_strings ==>
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# ["2495000", "Q63931", "CCKR_CAVPO", "2147182", "I51898",
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# "544724", "AAB29504.1", "Cavia"]
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# ckr.list_ids ==>
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# [["gi", "2495000"], ["sp", "Q63931", "CCKR_CAVPO"],
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# ["gi", "2147182"], ["pir", nil, "I51898"], ["gi", "544724"],
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# ["gb", "AAB29504.1", nil], ["Cavia"]]
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#
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# == References
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#
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# * FASTA format (WikiPedia)
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# http://en.wikipedia.org/wiki/FASTA_format
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#
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# * Fasta format description (NCBI)
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# http://www.ncbi.nlm.nih.gov/BLAST/fasta.shtml
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#
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module Bio
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#--
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# split from fasta.rb revision 1.28
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#++
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# Parsing FASTA Defline, and extract IDs and other informations.
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# or ":"-separated IDs.
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#
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# specs are described in:
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# ftp://ftp.ncbi.nih.gov/blast/documents/README.formatdb
|
79
|
+
# http://blast.wustl.edu/doc/FAQ-Indexing.html#Identifiers
|
80
|
+
#
|
81
|
+
# === Examples
|
82
|
+
#
|
83
|
+
# rub = Bio::FastaDefline.new('>gi|671595|emb|CAA85678.1| rubisco large subunit [Perovskia abrotanoides]')
|
84
|
+
# rub.entry_id ==> 'gi|671595'
|
85
|
+
# rub.get('emb') ==> 'CAA85678.1'
|
86
|
+
# rub.emb ==> 'CAA85678.1'
|
87
|
+
# rub.gi ==> '671595'
|
88
|
+
# rub.accession ==> 'CAA85678'
|
89
|
+
# rub.accessions ==> [ 'CAA85678' ]
|
90
|
+
# rub.acc_version ==> 'CAA85678.1'
|
91
|
+
# rub.locus ==> nil
|
92
|
+
# rub.list_ids ==> [["gi", "671595"],
|
93
|
+
# ["emb", "CAA85678.1", nil],
|
94
|
+
# ["Perovskia abrotanoides"]]
|
95
|
+
#
|
96
|
+
# ckr = Bio::FastaDefline.new(">gi|2495000|sp|Q63931|CCKR_CAVPO CHOLECYSTOKININ TYPE A RECEPTOR (CCK-A RECEPTOR) (CCK-AR)\001gi|2147182|pir||I51898 cholecystokinin A receptor - guinea pig\001gi|544724|gb|AAB29504.1| cholecystokinin A receptor; CCK-A receptor [Cavia]")
|
97
|
+
# ckr.entry_id ==> "gi|2495000"
|
98
|
+
# ckr.sp ==> "CCKR_CAVPO"
|
99
|
+
# ckr.pir ==> "I51898"
|
100
|
+
# ckr.gb ==> "AAB29504.1"
|
101
|
+
# ckr.gi ==> "2495000"
|
102
|
+
# ckr.accession ==> "AAB29504"
|
103
|
+
# ckr.accessions ==> ["Q63931", "AAB29504"]
|
104
|
+
# ckr.acc_version ==> "AAB29504.1"
|
105
|
+
# ckr.locus ==> nil
|
106
|
+
# ckr.description ==>
|
107
|
+
# "CHOLECYSTOKININ TYPE A RECEPTOR (CCK-A RECEPTOR) (CCK-AR)"
|
108
|
+
# ckr.descriptions ==>
|
109
|
+
# ["CHOLECYSTOKININ TYPE A RECEPTOR (CCK-A RECEPTOR) (CCK-AR)",
|
110
|
+
# "cholecystokinin A receptor - guinea pig",
|
111
|
+
# "cholecystokinin A receptor; CCK-A receptor [Cavia]"]
|
112
|
+
# ckr.words ==>
|
113
|
+
# ["cavia", "cck-a", "cck-ar", "cholecystokinin", "guinea", "pig",
|
114
|
+
# "receptor", "type"]
|
115
|
+
# ckr.id_strings ==>
|
116
|
+
# ["2495000", "Q63931", "CCKR_CAVPO", "2147182", "I51898",
|
117
|
+
# "544724", "AAB29504.1", "Cavia"]
|
118
|
+
# ckr.list_ids ==>
|
119
|
+
# [["gi", "2495000"], ["sp", "Q63931", "CCKR_CAVPO"],
|
120
|
+
# ["gi", "2147182"], ["pir", nil, "I51898"], ["gi", "544724"],
|
121
|
+
# ["gb", "AAB29504.1", nil], ["Cavia"]]
|
122
|
+
#
|
123
|
+
# === Refereneces
|
124
|
+
#
|
125
|
+
# * Fasta format description (NCBI)
|
126
|
+
# http://www.ncbi.nlm.nih.gov/BLAST/fasta.shtml
|
127
|
+
#
|
128
|
+
# * Frequently Asked Questions: Indexing of Sequence Identifiers (by Warren R. Gish.)
|
129
|
+
# http://blast.wustl.edu/doc/FAQ-Indexing.html#Identifiers
|
130
|
+
#
|
131
|
+
# * README.formatdb
|
132
|
+
# ftp://ftp.ncbi.nih.gov/blast/documents/README.formatdb
|
133
|
+
#
|
134
|
+
class FastaDefline
|
135
|
+
|
136
|
+
NSIDs = {
|
137
|
+
# NCBI and WU-BLAST
|
138
|
+
'gi' => [ 'gi' ], # NCBI GI
|
139
|
+
'gb' => [ 'acc_version', 'locus' ], # GenBank
|
140
|
+
'emb' => [ 'acc_version', 'locus' ], # EMBL
|
141
|
+
'dbj' => [ 'acc_version', 'locus' ], # DDBJ
|
142
|
+
'sp' => [ 'accession', 'entry_id' ], # SWISS-PROT
|
143
|
+
'pdb' => [ 'entry_id', 'chain' ], # PDB
|
144
|
+
'bbs' => [ 'number' ], # GenInfo Backbone Id
|
145
|
+
'gnl' => [ 'database' , 'entry_id' ], # General database identifier
|
146
|
+
'ref' => [ 'acc_version' , 'locus' ], # NCBI Reference Sequence
|
147
|
+
'lcl' => [ 'entry_id' ], # Local Sequence identifier
|
148
|
+
|
149
|
+
# WU-BLAST and NCBI
|
150
|
+
'pir' => [ 'accession', 'entry_id' ], # PIR
|
151
|
+
'prf' => [ 'accession', 'entry_id' ], # Protein Research Foundation
|
152
|
+
'pat' => [ 'country', 'number', 'serial' ], # Patents
|
153
|
+
|
154
|
+
# WU-BLAST only
|
155
|
+
'bbm' => [ 'number' ], # NCBI GenInfo Backbone database identifier
|
156
|
+
'gim' => [ 'number' ], # NCBI GenInfo Import identifier
|
157
|
+
'gp' => [ 'acc_version', 'locus' ], # GenPept
|
158
|
+
'oth' => [ 'accession', 'name', 'release' ], # Other (user-definable) identifier
|
159
|
+
'tpd' => [ 'accession', 'name' ], # Third party annotation, DDBJ
|
160
|
+
'tpe' => [ 'accession', 'name' ], # Third party annotation, EMBL
|
161
|
+
'tpg' => [ 'accession', 'name' ], # Third party annotation, GenBank
|
162
|
+
|
163
|
+
# Original
|
164
|
+
'ri' => [ 'entry_id', 'rearray_id', 'len' ], # RIKEN FANTOM DB
|
165
|
+
}
|
166
|
+
|
167
|
+
# Shows array that contains IDs (or ID-like strings).
|
168
|
+
# Returns an array of arrays of strings.
|
169
|
+
attr_reader :list_ids
|
170
|
+
|
171
|
+
# Shows a possibly unique identifier.
|
172
|
+
# Returns a string.
|
173
|
+
attr_reader :entry_id
|
174
|
+
|
175
|
+
# Parses given string.
|
176
|
+
def initialize(str)
|
177
|
+
@deflines = []
|
178
|
+
@info = {}
|
179
|
+
@list_ids = []
|
180
|
+
|
181
|
+
@entry_id = nil
|
182
|
+
|
183
|
+
lines = str.split("\x01")
|
184
|
+
lines.each do |line|
|
185
|
+
add_defline(line)
|
186
|
+
end
|
187
|
+
end #def initialize
|
188
|
+
|
189
|
+
# Parses given string and adds parsed data.
|
190
|
+
def add_defline(str)
|
191
|
+
case str
|
192
|
+
when /^\>?\s*((?:[^\|\s]*\|)+[^\s]+)\s*(.*)$/
|
193
|
+
# NSIDs
|
194
|
+
# examples:
|
195
|
+
# >gi|9910844|sp|Q9UWG2|RL3_METVA 50S ribosomal protein L3P
|
196
|
+
#
|
197
|
+
# note: regexp (:?) means grouping without backreferences
|
198
|
+
i = $1
|
199
|
+
d = $2
|
200
|
+
tks = i.split('|')
|
201
|
+
tks << '' if i[-1,1] == '|'
|
202
|
+
a = parse_NSIDs(tks)
|
203
|
+
i = a[0].join('|')
|
204
|
+
a.unshift('|')
|
205
|
+
d = tks.join('|') + ' ' + d unless tks.empty?
|
206
|
+
a << d
|
207
|
+
this_line = a
|
208
|
+
match_EC(d)
|
209
|
+
parse_square_brackets(d).each do |x|
|
210
|
+
if !match_EC(x, false) and x =~ /\A[A-Z]/ then
|
211
|
+
di = [ x ]
|
212
|
+
@list_ids << di
|
213
|
+
@info['organism'] = x unless @info['organism']
|
214
|
+
end
|
215
|
+
end
|
216
|
+
|
217
|
+
when /^\>?\s*([a-zA-Z0-9]+\:[^\s]+)\s*(.*)$/
|
218
|
+
# examples:
|
219
|
+
# >sce:YBR160W CDC28, SRM5; cyclin-dependent protein kinase catalytic subunit [EC:2.7.1.-] [SP:CC28_YEAST]
|
220
|
+
# >emb:CACDC28 [X80034] C.albicans CDC28 gene
|
221
|
+
i = $1
|
222
|
+
d = $2
|
223
|
+
a = parse_ColonSepID(i)
|
224
|
+
i = a.join(':')
|
225
|
+
this_line = [ ':', a , d ]
|
226
|
+
match_EC(d)
|
227
|
+
parse_square_brackets(d).each do |x|
|
228
|
+
if !match_EC(x, false) and x =~ /:/ then
|
229
|
+
parse_ColonSepID(x)
|
230
|
+
elsif x =~ /\A\s*([A-Z][A-Z0-9_\.]+)\s*\z/ then
|
231
|
+
@list_ids << [ $1 ]
|
232
|
+
end
|
233
|
+
end
|
234
|
+
|
235
|
+
when /^\>?\s*(\S+)(?:\s+(.+))?$/
|
236
|
+
# examples:
|
237
|
+
# >ABC12345 this is test
|
238
|
+
i = $1
|
239
|
+
d = $2.to_s
|
240
|
+
@list_ids << [ i.chomp('.') ]
|
241
|
+
this_line = [ '', [ i ], d ]
|
242
|
+
match_EC(d)
|
243
|
+
else
|
244
|
+
i = str
|
245
|
+
d = ''
|
246
|
+
match_EC(i)
|
247
|
+
this_line = [ '', [ i ], d ]
|
248
|
+
end
|
249
|
+
|
250
|
+
@deflines << this_line
|
251
|
+
@entry_id = i unless @entry_id
|
252
|
+
end
|
253
|
+
|
254
|
+
def match_EC(str, write_flag = true)
|
255
|
+
di = nil
|
256
|
+
str.scan(/EC\:((:?[\-\d]+\.){3}(:?[\-\d]+))/i) do |x|
|
257
|
+
di = [ 'EC', $1 ]
|
258
|
+
if write_flag then
|
259
|
+
@info['ec'] = di[1] if (!@info['ec'] or @info['ec'].to_s =~ /\-/)
|
260
|
+
@list_ids << di
|
261
|
+
end
|
262
|
+
end
|
263
|
+
di
|
264
|
+
end
|
265
|
+
private :match_EC
|
266
|
+
|
267
|
+
def parse_square_brackets(str)
|
268
|
+
r = []
|
269
|
+
str.scan(/\[([^\]]*)\]/) do |x|
|
270
|
+
r << x[0]
|
271
|
+
end
|
272
|
+
r
|
273
|
+
end
|
274
|
+
private :parse_square_brackets
|
275
|
+
|
276
|
+
def parse_ColonSepID(str)
|
277
|
+
di = str.split(':', 2)
|
278
|
+
di << nil if di.size <= 1
|
279
|
+
@list_ids << di
|
280
|
+
di
|
281
|
+
end
|
282
|
+
private :parse_ColonSepID
|
283
|
+
|
284
|
+
def parse_NSIDs(ary)
|
285
|
+
# this method destroys ary
|
286
|
+
data = []
|
287
|
+
while token = ary.shift
|
288
|
+
if labels = self.class::NSIDs[token] then
|
289
|
+
di = [ token ]
|
290
|
+
idtype = token
|
291
|
+
labels.each do |x|
|
292
|
+
token = ary.shift
|
293
|
+
break unless token
|
294
|
+
if self.class::NSIDs[token] then
|
295
|
+
ary.unshift(token)
|
296
|
+
break #each
|
297
|
+
end
|
298
|
+
if token.length > 0 then
|
299
|
+
di << token
|
300
|
+
else
|
301
|
+
di << nil
|
302
|
+
end
|
303
|
+
end
|
304
|
+
data << di
|
305
|
+
else
|
306
|
+
if token.length > 0 then
|
307
|
+
# UCID (uncontrolled identifiers)
|
308
|
+
di = [ token ]
|
309
|
+
data << di
|
310
|
+
@info['ucid'] = token unless @info['ucid']
|
311
|
+
end
|
312
|
+
break #while
|
313
|
+
end
|
314
|
+
end #while
|
315
|
+
@list_ids.concat data
|
316
|
+
data
|
317
|
+
end #def parse_NSIDs
|
318
|
+
private :parse_NSIDs
|
319
|
+
|
320
|
+
|
321
|
+
# Shows original string.
|
322
|
+
# Note that the result of this method may be different from
|
323
|
+
# original string which is given in FastaDefline.new method.
|
324
|
+
def to_s
|
325
|
+
@deflines.collect { |a|
|
326
|
+
s = a[0]
|
327
|
+
(a[1..-2].collect { |x| x.join(s) }.join(s) + ' ' + a[-1]).strip
|
328
|
+
}.join("\x01")
|
329
|
+
end
|
330
|
+
|
331
|
+
# Shows description.
|
332
|
+
def description
|
333
|
+
@deflines[0].to_a[-1]
|
334
|
+
end
|
335
|
+
|
336
|
+
# Returns descriptions.
|
337
|
+
def descriptions
|
338
|
+
@deflines.collect do |a|
|
339
|
+
a[-1]
|
340
|
+
end
|
341
|
+
end
|
342
|
+
|
343
|
+
# Shows ID-like strings.
|
344
|
+
# Returns an array of strings.
|
345
|
+
def id_strings
|
346
|
+
r = []
|
347
|
+
@list_ids.each do |a|
|
348
|
+
if a.size >= 2 then
|
349
|
+
r.concat a[1..-1].find_all { |x| x }
|
350
|
+
else
|
351
|
+
if a[0].to_s.size > 0 and a[0] =~ /\A[A-Za-z0-9\.\-\_]+\z/
|
352
|
+
r << a[0]
|
353
|
+
end
|
354
|
+
end
|
355
|
+
end
|
356
|
+
r.concat( words(true, []).find_all do |x|
|
357
|
+
x =~ /\A[A-Z][A-Za-z0-9\_]*[0-9]+[A-Za-z0-9\_]+\z/ or
|
358
|
+
x =~ /\A[A-Z][A-Z0-9]*\_[A-Z0-9\_]+\z/
|
359
|
+
end)
|
360
|
+
r
|
361
|
+
end
|
362
|
+
|
363
|
+
KillWords = [
|
364
|
+
'an', 'the', 'this', 'that',
|
365
|
+
'is', 'are', 'were', 'was', 'be', 'can', 'may', 'might',
|
366
|
+
'as', 'at', 'by', 'for', 'in', 'of', 'on', 'to', 'with',
|
367
|
+
'from', 'and', 'or', 'not',
|
368
|
+
'dna', 'rna', 'mrna', 'cdna', 'orf',
|
369
|
+
'aa', 'nt', 'pct', 'id', 'ec', 'sp', 'subsp',
|
370
|
+
'similar', 'involved', 'identical', 'identity',
|
371
|
+
'cds', 'clone', 'library', 'contig', 'contigs',
|
372
|
+
'homolog', 'homologue', 'homologs', 'homologous',
|
373
|
+
'protein', 'proteins', 'gene', 'genes',
|
374
|
+
'product', 'products', 'sequence', 'sequences',
|
375
|
+
'strain', 'strains', 'region', 'regions',
|
376
|
+
]
|
377
|
+
KillWordsHash = {}
|
378
|
+
KillWords.each { |x| KillWordsHash[x] = true }
|
379
|
+
|
380
|
+
KillRegexpArray = [
|
381
|
+
/\A\d{1,3}\%?\z/,
|
382
|
+
/\A[A-Z][A-Za-z0-9\_]*[0-9]+[A-Za-z0-9\_]+\z/,
|
383
|
+
/\A[A-Z][A-Z0-9]*\_[A-Z0-9\_]+\z/
|
384
|
+
]
|
385
|
+
|
386
|
+
# Shows words used in the defline. Returns an Array.
|
387
|
+
def words(case_sensitive = nil, kill_regexp = self.class::KillRegexpArray,
|
388
|
+
kwhash = self.class::KillWordsHash)
|
389
|
+
a = descriptions.join(' ').split(/[\.\,\;\:\(\)\[\]\{\}\<\>\"\'\`\~\/\|\?\!\&\@\#\s\x00-\x1f\x7f]+/)
|
390
|
+
a.collect! do |x|
|
391
|
+
x.sub!(/\A[\$\*\-\+]+/, '')
|
392
|
+
x.sub!(/[\$\*\-\=]+\z/, '')
|
393
|
+
if x.size <= 1 then
|
394
|
+
nil
|
395
|
+
elsif kwhash[x.downcase] then
|
396
|
+
nil
|
397
|
+
else
|
398
|
+
if kill_regexp.find { |expr| expr =~ x } then
|
399
|
+
nil
|
400
|
+
else
|
401
|
+
x
|
402
|
+
end
|
403
|
+
end
|
404
|
+
end
|
405
|
+
a.compact!
|
406
|
+
a.collect! { |x| x.downcase } unless case_sensitive
|
407
|
+
a.sort!
|
408
|
+
a.uniq!
|
409
|
+
a
|
410
|
+
end
|
411
|
+
|
412
|
+
# Returns identifires by a database name.
|
413
|
+
def get(dbname)
|
414
|
+
db = dbname.to_s
|
415
|
+
r = nil
|
416
|
+
unless r = @info[db] then
|
417
|
+
di = @list_ids.find { |x| x[0] == db.to_s }
|
418
|
+
if di and di.size <= 2 then
|
419
|
+
r = di[-1]
|
420
|
+
elsif di then
|
421
|
+
labels = self.class::NSIDs[db]
|
422
|
+
[ 'acc_version', 'entry_id',
|
423
|
+
'locus', 'accession', 'number'].each do |x|
|
424
|
+
if i = labels.index(x) then
|
425
|
+
r = di[i+1]
|
426
|
+
break if r
|
427
|
+
end
|
428
|
+
end
|
429
|
+
r = di[1..-1].find { |x| x } unless r
|
430
|
+
end
|
431
|
+
@info[db] = r if r
|
432
|
+
end
|
433
|
+
r
|
434
|
+
end
|
435
|
+
|
436
|
+
# Returns an identifier by given type.
|
437
|
+
def get_by_type(type_str)
|
438
|
+
@list_ids.each do |x|
|
439
|
+
if labels = self.class::NSIDs[x[0]] then
|
440
|
+
if i = labels.index(type_str) then
|
441
|
+
return x[i+1]
|
442
|
+
end
|
443
|
+
end
|
444
|
+
end
|
445
|
+
nil
|
446
|
+
end
|
447
|
+
|
448
|
+
# Returns identifiers by given type.
|
449
|
+
def get_all_by_type(*type_strarg)
|
450
|
+
d = []
|
451
|
+
@list_ids.each do |x|
|
452
|
+
if labels = self.class::NSIDs[x[0]] then
|
453
|
+
type_strarg.each do |y|
|
454
|
+
if i = labels.index(y) then
|
455
|
+
d << x[i+1] if x[i+1]
|
456
|
+
end
|
457
|
+
end
|
458
|
+
end
|
459
|
+
end
|
460
|
+
d
|
461
|
+
end
|
462
|
+
|
463
|
+
# Shows locus.
|
464
|
+
# If the entry has more than two of such IDs,
|
465
|
+
# only the first ID are shown.
|
466
|
+
# Returns a string or nil.
|
467
|
+
def locus
|
468
|
+
unless defined?(@locus)
|
469
|
+
@locus = get_by_type('locus')
|
470
|
+
end
|
471
|
+
@locus
|
472
|
+
end
|
473
|
+
|
474
|
+
# Shows GI.
|
475
|
+
# If the entry has more than two of such IDs,
|
476
|
+
# only the first ID are shown.
|
477
|
+
# Returns a string or nil.
|
478
|
+
def gi
|
479
|
+
unless defined?(@gi) then
|
480
|
+
@gi = get_by_type('gi')
|
481
|
+
end
|
482
|
+
@gi
|
483
|
+
end
|
484
|
+
|
485
|
+
# Shows accession with version number.
|
486
|
+
# If the entry has more than two of such IDs,
|
487
|
+
# only the first ID are shown.
|
488
|
+
# Returns a string or nil.
|
489
|
+
def acc_version
|
490
|
+
unless defined?(@acc_version) then
|
491
|
+
@acc_version = get_by_type('acc_version')
|
492
|
+
end
|
493
|
+
@acc_version
|
494
|
+
end
|
495
|
+
|
496
|
+
# Shows accession numbers.
|
497
|
+
# Returns an array of strings.
|
498
|
+
def accessions
|
499
|
+
unless defined?(@accessions) then
|
500
|
+
@accessions = get_all_by_type('accession', 'acc_version')
|
501
|
+
@accessions.collect! { |x| x.sub(/\..*\z/, '') }
|
502
|
+
end
|
503
|
+
@accessions
|
504
|
+
end
|
505
|
+
|
506
|
+
# Shows an accession number.
|
507
|
+
def accession
|
508
|
+
unless defined?(@accession) then
|
509
|
+
if acc_version then
|
510
|
+
@accession = acc_version.split('.')[0]
|
511
|
+
else
|
512
|
+
@accession = accessions[0]
|
513
|
+
end
|
514
|
+
end
|
515
|
+
@accession
|
516
|
+
end
|
517
|
+
|
518
|
+
def method_missing(name, *args)
|
519
|
+
# raise ArgumentError,
|
520
|
+
# "wrong # of arguments(#{args.size} for 1)" if args.size >= 2
|
521
|
+
r = get(name, *args)
|
522
|
+
if !r and !(self.class::NSIDs[name.to_s]) then
|
523
|
+
raise "NameError: undefined method `#{name.inspect}'"
|
524
|
+
end
|
525
|
+
r
|
526
|
+
end
|
527
|
+
|
528
|
+
|
529
|
+
end #class FastaDefline
|
530
|
+
|
531
|
+
end #module Bio
|
532
|
+
|