scout-browser 4.99.0__py3-none-any.whl → 4.100.0__py3-none-any.whl

scout/server/blueprints/variants/templates/variants/utils.html

@@ -193,9 +193,9 @@
         {% endif %}
           <td>
               {% if compound.not_loaded %}
-                {{ compound.display_name }} <small>(not loaded)</small>
+                {{ compound.display_name|truncate(20, True) }} <small>(not loaded)</small>
               {% elif is_popover %}
-                {{ compound.display_name }}
+                {{ compound.display_name|truncate(20, True) }}
               {% else %}
                 <a href='{{ url_for("variant.variant",
                 institute_id=institute._id,
@@ -218,7 +218,7 @@
           <td>
             {% for annotation in compound.functional_annotations %}
               {{ annotation }}<br>
-            {% endfor %}
+            {% endfor %}x
           </td>
         </tr>
       {% endfor %}
@@ -243,7 +243,7 @@
             {{ pretty_link_variant(variant, case) }}
           </td>
           <td class='text-end'>{{ variant.sub_category }}</td>
-          <td class='text-end'>{{ variant.length if variant.length < 100000000000 else '-' }}</td>
+          <td class='text-end'>{{ variant.length if variant.length and variant.length < 100000000000 else '-' }}</td>
           <td class='text-end'>{{ variant.rank_score }}</td>
         </tr>
       {% endfor %}
@@ -332,7 +332,7 @@
       {{ form.spidex_human(class="selectpicker", data_style="btn-secondary") }}
     </div>
     <div class="col-2">
-      <span>{{ form.clinsig.label(class="control-label") }}</span>
+      <span>{{ form.clinsig.label(class="control-label", data_bs_toggle="tooltip", data_bs_placement="left", title="Germline classification criteria.") }}</span>
       <span style="float:right;">{{ form.clinsig_exclude.label(class="control-label", data_bs_toggle="tooltip", data_bs_placement="left", title="Exclude variants with clinical significance among the selected categories.") }} {{form.clinsig_exclude}}</span>
       {{ form.clinsig(class="selectpicker", data_style="btn-secondary") }}
     </div>
@@ -621,7 +621,7 @@
     </div>
   </div>
   <div class="col-2">
-    {{ form.clinsig.label(class="control-label") }}
+    {{ form.clinsig.label(class="control-label", data_bs_toggle="tooltip", data_bs_placement="left", title="Germline classification criteria.") }}
     {{ form.clinsig(class="selectpicker", data_style="btn-secondary") }}
   </div>
   <div class="col-1">
@@ -722,26 +722,17 @@
         {{ form.genetic_models(class="selectpicker", data_style="btn-secondary") }}
       </div>
       <div class="col-2">
-        <span>{{ form.clinsig.label(class="control-label") }}</span>
+        <span>{{ form.clinsig.label(class="control-label", data_bs_toggle="tooltip", data_bs_placement="left", title="Germline classification criteria.") }}</span>
         <span style="float:right;">{{ form.clinsig_exclude.label(class="control-label", data_bs_toggle="tooltip", data_bs_placement="left", title="Exclude variants with clinical significance among the selected categories.") }} {{form.clinsig_exclude}}</span>
         {{ form.clinsig(class="selectpicker", data_style="btn-secondary") }}
       </div>
       <div class="col-2">
-        <div class="form-check d-flex justify-content-start">
-          {{ form.mvl_tag(class="form-check-input",type="checkbox") }}
-          {{ form.mvl_tag.label(class="ms-2 form-check-label") }}
-        </div>
-        <div class="form-check d-flex justify-content-start">
-          {{ form.clinvar_tag(class="form-check-input",type="checkbox") }}
-          {{ form.clinvar_tag.label(class="ms-2 form-check-label") }}
-        </div>
-        <div class="form-check d-flex justify-content-start">
-          {{ form.cosmic_tag(class="form-check-input",type="checkbox") }}
-          {{ form.cosmic_tag.label(class="ms-2 form-check-label") }}
-        </div>
+        <span>{{ form.clinsig_onc.label(class="control-label", data_bs_toggle="tooltip", data_bs_placement="left", title="ClinVar oncogenicity criteria will be applied alongside the other search criteria, not as an alternative. Oncogenicity annotations are still sparse in ClinVar, so relying solely on them could be too restrictive.") }}</span>
+        <span style="float:right;">{{ form.clinsig_onc_exclude.label(class="control-label", data_bs_toggle="tooltip", data_bs_placement="left", title="Exclude variants with oncogenicity among the selected categories.") }} {{form.clinsig_onc_exclude}}</span>
+        {{ form.clinsig_onc(class="selectpicker", data_style="btn-secondary") }}
       </div>
     </div>
-    <div class="row">
+    <div class="row mt-2">
       <div class="col-4">
         {{ form.hgnc_symbols.label(class="control-label") }}
         {{ form.hgnc_symbols(class="form-control") }}
@@ -762,14 +753,28 @@
         {{ form.alt_count.label(class="control-label") }}
         {{ form.alt_count(class="form-control") }}
       </div>
-      <div class="col-2">
+      <div class="col-1">
         {{ form.tumor_frequency.label(class="control-label") }}
         {{ form.tumor_frequency(class="form-control", min="0", max=1) }}
       </div>
-      <div class="col-2">
+      <div class="col-1">
         {{ form.control_frequency.label(class="control-label") }}
         {{ form.control_frequency(class="form-control", min="0", max=1) }}
       </div>
+      <div class="col-2">
+        <div class="form-check d-flex justify-content-start">
+          {{ form.mvl_tag(class="form-check-input",type="checkbox") }}
+          {{ form.mvl_tag.label(class="ms-2 form-check-label") }}
+        </div>
+        <div class="form-check d-flex justify-content-start">
+          {{ form.clinvar_tag(class="form-check-input",type="checkbox") }}
+          {{ form.clinvar_tag.label(class="ms-2 form-check-label") }}
+        </div>
+        <div class="form-check d-flex justify-content-start">
+          {{ form.cosmic_tag(class="form-check-input",type="checkbox") }}
+          {{ form.cosmic_tag.label(class="ms-2 form-check-label") }}
+        </div>
+      </div>
     </div>
     <div class="form" id="chromosome_search">
       <div class="row" style="margin-top:20px;">
@@ -861,7 +866,7 @@
         {{ form.genetic_models(class="selectpicker", data_style="btn-secondary") }}
       </div>
       <div class="col-2">
-        {{ form.clinsig.label(class="control-label") }}
+        {{ form.clinsig.label(class="control-label", data_bs_toggle="tooltip", data_bs_placement="left", title="Germline classification criteria.") }}
         {{ form.clinsig(class="selectpicker", data_style="btn-secondary") }}
       </div>
     </div>

scout/server/extensions/bionano_extension.py

@@ -7,7 +7,6 @@ For further development, the server has a Swagger-like demo interface at https:/
 which is useful for details, and for sniffing actual message content structure, required cookie variable names etc.
 """
 
-import json
 import logging
 from typing import Dict, Iterable, List, Optional, Tuple
 

scout/server/extensions/chanjo2_extension.py

@@ -1,11 +1,13 @@
 import logging
-from typing import Dict, List
+from typing import Dict
 
 import requests
-from flask import current_app
+from flask import Flask, current_app
+
+from scout.server.utils import get_case_mito_chromosome
+from scout.utils.scout_requests import get_request_json, post_request_json
 
 REF_CHROM = "14"
-MT_CHROM = "MT"
 LOG = logging.getLogger(__name__)
 
 CHANJO_BUILD_37 = "GRCh37"
@@ -15,14 +17,33 @@ CHANJO_BUILD_38 = "GRCh38"
 class Chanjo2Client:
     """Runs requests to chanjo2 and returns results in the expected format."""
 
-    def mt_coverage_stats(self, individuals: dict) -> Dict[str, dict]:
+    def init_app(self, app: Flask):
+        """The chanjo2 client has nothing to init, just check chanjo2 heartbeat."""
+        self.get_status(app)
+
+    def get_status(self, app: Flask) -> dict:
+        """Check Chanjo2 heartbeat, LOG status and return status."""
+        chanjo2_heartbeat_url: str = app.config.get("CHANJO2_URL")
+        json_resp = get_request_json(chanjo2_heartbeat_url)
+
+        if not json_resp:
+            LOG.warning(
+                f"Chanjo2 is configured at {chanjo2_heartbeat_url} but does not return heartbeat."
+            )
+            return json_resp
+
+        LOG.info(f"{json_resp.get('content',{}).get('message')}")
+        return json_resp
+
+    def mt_coverage_stats(self, case_obj: dict) -> Dict[str, dict]:
         """Sends a POST requests to the chanjo2 coverage/d4/interval to collect stats for the MT case report."""
 
         chanjo2_chrom_cov_url: str = "/".join(
             [current_app.config.get("CHANJO2_URL"), "coverage/d4/interval/"]
         )
         coverage_stats = {}
-        for ind in individuals:
+        case_mt_chrom = get_case_mito_chromosome(case_obj)
+        for ind in case_obj.get("individuals", []):
 
             if not ind.get("d4_file"):
                 continue
@@ -30,14 +51,21 @@ class Chanjo2Client:
 
             # Get mean coverage over chr14
             chrom_cov_query["chromosome"] = REF_CHROM
-            resp = requests.post(chanjo2_chrom_cov_url, json=chrom_cov_query)
-            autosome_cov = resp.json().get("mean_coverage")
 
-            # Get mean coverage over chrMT
-            chrom_cov_query["chromosome"] = MT_CHROM
-            resp = requests.post(chanjo2_chrom_cov_url, json=chrom_cov_query)
+            autosome_cov_json = post_request_json(chanjo2_chrom_cov_url, chrom_cov_query)
+            if autosome_cov_json.get("status_code") != 200:
+                raise ValueError(
+                    f"Chanjo2 get autosome coverage failed: {autosome_cov_json.get('message')}"
+                )
+
+            autosome_cov = autosome_cov_json.get("content", {}).get("mean_coverage")
 
-            mt_cov = resp.json().get("mean_coverage")
+            # Get mean coverage over chrMT
+            chrom_cov_query["chromosome"] = case_mt_chrom
+            mt_cov_json = post_request_json(chanjo2_chrom_cov_url, chrom_cov_query)
+            if mt_cov_json.get("status_code") != 200:
+                raise ValueError(f"Chanjo2 get MT coverage failed: {mt_cov_json.get('message')}")
+            mt_cov = mt_cov_json.get("content", {}).get("mean_coverage")
 
             coverage_info = dict(
                 mt_coverage=mt_cov,
@@ -66,6 +94,8 @@ class Chanjo2Client:
             "interval_type": "genes",
             "samples": [],
         }
+        analysis_types = []
+
         for ind in individuals:
             if not ind.get("d4_file"):
                 continue
@@ -73,10 +103,21 @@ class Chanjo2Client:
             gene_cov_query["samples"].append(
                 {"coverage_file_path": ind["d4_file"], "name": ind["individual_id"]}
             )
+            analysis_types.append(ind.get("analysis_type"))
 
-        resp = requests.post(chanjo2_gene_cov_url, json=gene_cov_query)
-        gene_cov = resp.json()
+        if "wes" in analysis_types:
+            gene_cov_query["interval_type"] = "exons"
+        elif "wts" in analysis_types:
+            gene_cov_query["interval_type"] = "transcripts"
+
+        gene_cov_json = post_request_json(chanjo2_gene_cov_url, gene_cov_query)
+
+        if gene_cov_json.get("status_code") != 200:
+            raise ValueError(
+                f"Chanjo2 get complete coverage failed: {gene_cov_json.get('message')}"
+            )
 
+        gene_cov = gene_cov_json.get("content")
         full_coverage = bool(gene_cov)
         for sample in gene_cov.keys():
             if gene_cov[sample]["coverage_completeness_percent"] < 100:

scout/server/links.py

@@ -54,6 +54,7 @@ def add_gene_links(
     gene_obj["string_link"] = string(ensembl_id)
     gene_obj["reactome_link"] = reactome(ensembl_id)
     gene_obj["clingen_link"] = clingen(hgnc_id)
+    gene_obj["cspec_link"] = clingen_cspec(hgnc_id)
     gene_obj["gencc_link"] = gencc(hgnc_id)
     gene_obj["expression_atlas_link"] = expression_atlas(ensembl_id)
     gene_obj["exac_link"] = exac(ensembl_id)
@@ -80,6 +81,7 @@ def add_gene_links(
     gene_obj["gnomad_str_link"] = gnomad_str_gene(hgnc_symbol)
     gene_obj["panelapp_link"] = panelapp_gene(hgnc_symbol)
     gene_obj["decipher_link"] = decipher_gene(hgnc_symbol)
+    gene_obj["cancer_hotspots_link"] = cancer_hotspots_gene(hgnc_symbol)
     if institute:
         gene_obj["alamut_link"] = alamut_gene_link(institute, gene_obj, build)
 
@@ -90,6 +92,12 @@ def decipher_gene(hgnc_symbol: str) -> Optional[str]:
         return f"https://www.deciphergenomics.org/gene/{hgnc_symbol}/overview/clinical-info"
 
 
+def cancer_hotspots_gene(hgnc_symbol: str) -> Optional[str]:
+    """Create link to Decipher gene."""
+    if hgnc_symbol:
+        return f"https://www.cancerhotspots.org/#/home?search={hgnc_symbol}"
+
+
 def panelapp_gene(hgnc_symbol):
     link = "https://panelapp.genomicsengland.co.uk/panels/entities/{}"
 
@@ -250,6 +258,13 @@ def clingen(hgnc_id):
     return link.format(hgnc_id)
 
 
+def clingen_cspec(hgnc_id):
+    link = "https://cspec.genome.network/cspec/ui/svi/?search=HGNC:{}"
+    if not hgnc_id:
+        return None
+    return link.format(hgnc_id)
+
+
 def gencc(hgnc_id):
     link = "https://search.thegencc.org/genes/HGNC:{}"
     if not hgnc_id:

scout/server/static/bs_styles.css

@@ -371,6 +371,23 @@ body {
 }
 /* end of sidebar-related stuff */
 
+/* A collapse icon for button use */
+.btn[aria-expanded="false"] .collapse-button-icon::before {
+  content: " \f0da";
+  font-family: "Font Awesome 5 Free", ui-monospace;
+  font-weight: 900;
+  display: inline;
+  text-align: left;
+}
+
+.btn[aria-expanded="true"] .collapse-button-icon::before {
+  content: " \f0d7";
+  font-family: "Font Awesome 5 Free", ui-monospace;
+  font-weight: 900;
+  display: inline;
+  text-align: left;
+
+
 option {
   width: 100%;
 }
@@ -386,9 +403,20 @@ option {
 }
 
 .str-variants-reviewer-container {
-   padding: 20px 5px;
- }
- .str-variants-reviewer-container svg {
-   width: 100%;
-   height: auto;
- }
+	padding: 20px 5px;
+}
+
+.str-variants-reviewer-container svg {
+	width: 100%;
+	height: auto;
+}
+
+.blink_me {
+	animation: blinker 2s linear infinite;
+}
+
+@keyframes blinker {
+	 50% {
+    opacity: 0;
+  }
+}

scout/server/templates/utils.html

@@ -234,16 +234,15 @@
 {% endmacro %}
 
 {% macro db_table_external_stylesheets() %}
-  <link rel="stylesheet" href="https://cdn.datatables.net/1.12.0/css/dataTables.bootstrap5.min.css" integrity="sha512-r9doM4NDlA2Cr0R56ielwMfkzL8miUuqbwNV4G1detiqlX58aTINapm2g2CoASFYedwgn3ulX6xmcDmRS0bmzw==" crossorigin="anonymous">
-  <link rel="stylesheet" href="https://cdn.datatables.net/buttons/2.2.3/css/buttons.dataTables.min.css" integrity="sha512-tnmsL7vm/5wo8jsDSW4033D6dW3xn8qyIDZTIssv/3YKyLU3pMg5IZB0k88RGmZPlyyUoK7EEghuaoXZIinDXA==" crossorigin="anonymous">
-  <link rel="stylesheet" href="https://cdn.datatables.net/buttons/2.2.3/css/buttons.bootstrap5.min.css" integrity="sha512-VX0h3jcn1Oc0lFy0aRxuq6U/tTk/6Ryurar5O3Az2DHLA1mpURv2Zgzl5MJJ5weChE7rdlsiB/ka5rUstkTN8g==" crossorigin="anonymous">
-  {% endmacro %}
+  <link rel="stylesheet" href="https://cdn.datatables.net/2.2.2/css/dataTables.bootstrap5.min.css" integrity="sha512-pVSTZJo4Kj/eLMUG1w+itkGx+scwF00G5dMb02FjgU9WwF7F/cpZvu1Bf1ojA3iAf8y94cltGnuPV9vwv3CgZw==" referrerpolicy="no-referrer" crossorigin="anonymous">
+  <link rel="stylesheet" href="https://cdn.datatables.net/buttons/3.2.2/css/buttons.bootstrap5.min.css" integrity="sha512-9Mi4C/wtfinscXIdOGZvqv0ZYvhBUOQCrwqmTZyiYuEgJQHWnXenkYQOC44I3kyh7uaOmz9eNxeMkC8xGBLOWg==" referrerpolicy="no-referrer" crossorigin="anonymous">
+{% endmacro %}
 
 {% macro db_table_external_scripts() %}
-  <script src="https://cdn.datatables.net/1.12.0/js/jquery.dataTables.min.js" integrity="sha512-fu0WiDG5xqtX2iWk7cp17Q9so54SC+5lk/z/glzwlKFdEOwGG6piUseP2Sik9hlvlmyOJ0lKXRSuv1ltdVk9Jg==" referrerpolicy="no-referrer" crossorigin="anonymous"></script>
-  <script src="https://cdn.datatables.net/1.12.0/js/dataTables.bootstrap5.min.js" integrity="sha512-nfoMMJ2SPcUdaoGdaRVA1XZpBVyDGhKQ/DCedW2k93MTRphPVXgaDoYV1M/AJQLCiw/cl2Nbf9pbISGqIEQRmQ==" referrerpolicy="no-referrer" crossorigin="anonymous"></script>
-  <script src="https://cdn.datatables.net/buttons/2.2.3/js/dataTables.buttons.min.js" integrity="sha512-QT3oEXamRhx0x+SRDcgisygyWze0UicgNLFM9Dj5QfJuu2TVyw7xRQfmB0g7Z5/TgCdYKNW15QumLBGWoPefYg==" referrerpolicy="no-referrer" crossorigin="anonymous"></script>
-  <script src="https://cdnjs.cloudflare.com/ajax/libs/jszip/3.2.0/jszip.min.js" integrity="sha512-0zVs73boVJk7Mlo/06K7cX+GWqW4xv0waiKkfXPGEhQ3Ww3UznkFlywBKIx4XetI/StJwac4bUNoeBGJY3Yugw==" referrerpolicy="no-referrer" crossorigin="anonymous"></script>
-  <script src="https://cdn.datatables.net/buttons/2.2.3/js/buttons.html5.js" integrity="sha512-BSdPiqLbAJOVF1Q+rleIJJIio/8Ihf1zXxfYMinSHMpKdRWX634Mi4Rt8LRYfn0k5nbSlFO7Y7klzNCG8tokFQ==" referrerpolicy="no-referrer" crossorigin="anonymous"></script>
-  <script src="https://cdn.datatables.net/buttons/2.2.3/js/buttons.bootstrap5.js" integrity="sha512-ZA1gDCJI+Hul95Y1tSRi3D/GfWRRX11oJH+QqtjnpzJLBDmU9DsO2db5oL3Gn7LezkSL/XWCL5v04ZiCy/RpKQ==" referrerpolicy="no-referrer" crossorigin="anonymous"></script>
+  <script src="https://cdn.datatables.net/2.2.2/js/dataTables.min.js" integrity="sha512-iwuEh+XTZQNzwdjYrqsxyWJXyReKVclGX4D2uGYBGNIR6o0VBwIfeYQv+lQjxmye87K6C6mc7qrqJlCcaeZJhA==" referrerpolicy="no-referrer" crossorigin="anonymous"></script>
+  <script src="https://cdn.datatables.net/2.2.2/js/dataTables.bootstrap5.min.js" integrity="sha512-Cwi0jz7fz7mrX990DlJ1+rmiH/D9/rjfOoEex8C9qrPRDDqwMPdWV7pJFKzhM10gAAPlufZcWhfMuPN699Ej0w==" referrerpolicy="no-referrer" crossorigin="anonymous"></script>
+  <script src="https://cdn.datatables.net/buttons/3.2.2/js/dataTables.buttons.min.js" integrity="sha512-T/4qQRgBJ8Ev6Lk8M943pMIbCpgqtVf5XI77hxe3nQn0f9a0gn/WKXWMbuGv6cpjp9NM8Mc+3/3GnpW+3+TckA==" referrerpolicy="no-referrer" crossorigin="anonymous"></script>
+  <script src="https://cdnjs.cloudflare.com/ajax/libs/jszip/3.10.1/jszip.min.js" integrity="sha512-XMVd28F1oH/O71fzwBnV7HucLxVwtxf26XV8P4wPk26EDxuGZ91N8bsOttmnomcCD3CS5ZMRL50H0GgOHvegtg==" referrerpolicy="no-referrer" crossorigin="anonymous"></script>
+  <script src="https://cdn.datatables.net/buttons/3.2.2/js/buttons.html5.min.js" integrity="sha512-I86DAquH004N60kPVNHp+9QkC5y61C5ODHj6ewhddXnewOJ31wyOJHNlNEr8NUR3xqtGozfMb557So1pR0uDCA==" referrerpolicy="no-referrer" crossorigin="anonymous"></script>
+  <script src="https://cdn.datatables.net/buttons/3.2.2/js/buttons.bootstrap5.min.js" integrity="sha512-rVAaUqNTbX7lADp767RxnIMvbROobK+gn7SpbbPc+qMUPotgAkSsRhCKF5ziUEquBsdGcv3eOaZK1fIbGwh5CA==" referrerpolicy="no-referrer" crossorigin="anonymous"></script>
 {% endmacro %}

scout/server/utils.py

@@ -206,6 +206,19 @@ def user_institutes(store, login_user):
     return institutes
 
 
+def get_case_genome_build(case_obj: dict) -> str:
+    """returns the genome build of a case, as a string."""
+    return "38" if "38" in case_obj.get("genome_build", "37") else "37"
+
+
+def get_case_mito_chromosome(case_obj: dict) -> str:
+    """Returns MT or M, according to the genome build of a case."""
+    case_build = get_case_genome_build(case_obj)
+    if case_build == "38":
+        return "M"
+    return "MT"
+
+
 def case_has_mtdna_report(case_obj: dict):
     """Display mtDNA report on the case sidebar only for some specific cases."""
     if case_obj.get("track", "rare") == "cancer":
@@ -326,6 +339,11 @@ def case_append_alignments(case_obj: dict):
         {"path": "rhocall_wig", "append_to": "rhocall_wigs", "index": None},
         {"path": "upd_regions_bed", "append_to": "upd_regions_beds", "index": None},
         {"path": "upd_sites_bed", "append_to": "upd_sites_beds", "index": None},
+        {
+            "path": "minor_allele_frequency_wig",
+            "append_to": "minor_allele_frequency_wigs",
+            "index": None,
+        },
         {"path": "tiddit_coverage_wig", "append_to": "tiddit_coverage_wigs", "index": None},
     ]
 

scout/utils/ensembl_biomart_clients.py

@@ -7,6 +7,7 @@ LOG = logging.getLogger(__name__)
 SCHUG_BASE = "https://schug.scilifelab.se"
 
 BUILDS: Dict[str, str] = {"37": "GRCh37", "38": "GRCh38"}
+CHROM_SEPARATOR = "[success]"
 
 SCHUG_RESOURCE_URL: Dict[str, str] = {
     "genes": "/genes/ensembl_genes/?build=",

scout/utils/scout_requests.py

@@ -8,7 +8,6 @@ from urllib.error import HTTPError
 
 import requests
 from defusedxml import ElementTree
-from flask import flash
 
 from scout.constants import HPO_URL, HPOTERMS_URL, ORPHA_URLS
 
@@ -344,7 +343,7 @@ def fetch_constraint():
         return exac_lines
 
 
-def fetch_refseq_version(refseq_acc):
+def fetch_refseq_version(refseq_acc: str) -> str:
     """Fetch refseq version from entrez and return refseq version
 
     Args:
@@ -362,7 +361,6 @@ def fetch_refseq_version(refseq_acc):
     try:
         resp = get_request(base_url.format(refseq_acc))
         if resp is None:
-            flash(f"Error: could not retrieve HGVS version for {refseq_acc} from Entrez eutils!")
             return version
         tree = ElementTree.fromstring(resp.content)
         version = tree.find("IdList").find("Id").text or version

{scout_browser-4.99.0.dist-info → scout_browser-4.100.0.dist-info}/METADATA

@@ -1,6 +1,6 @@
 Metadata-Version: 2.4
 Name: scout-browser
-Version: 4.99.0
+Version: 4.100.0
 Summary: Clinical DNA variant visualizer and browser
 Project-URL: Repository, https://github.com/Clinical-Genomics/scout
 Project-URL: Changelog, https://github.com/Clinical-Genomics/scout/blob/main/CHANGELOG.md