@weng-lab/ui-components 3.0.0 → 3.0.1-beta.0

package/dist/ui-components.es56.js

@@ -1,35 +1,252 @@
-import e from "./ui-components.es89.js";
-import o from "./ui-components.es96.js";
-import r from "./ui-components.es97.js";
-import t from "./ui-components.es98.js";
-import m from "./ui-components.es99.js";
-import a from "./ui-components.es100.js";
-const p = a(), s = t({
-  themeId: o,
-  defaultTheme: p,
-  defaultClassName: r.root,
-  generateClassName: m.generate
-});
-process.env.NODE_ENV !== "production" && (s.propTypes = {
-  // ┌────────────────────────────── Warning ──────────────────────────────┐
-  // │ These PropTypes are generated from the TypeScript type definitions. │
-  // │    To update them, edit the d.ts file and run `pnpm proptypes`.     │
-  // └─────────────────────────────────────────────────────────────────────┘
-  /**
-   * @ignore
-   */
-  children: e.node,
-  /**
-   * The component used for the root node.
-   * Either a string to use a HTML element or a component.
-   */
-  component: e.elementType,
-  /**
-   * The system prop that allows defining system overrides as well as additional CSS styles.
-   */
-  sx: e.oneOfType([e.arrayOf(e.oneOfType([e.func, e.object, e.bool])), e.func, e.object])
-});
+const d = `
+  query suggestions($assembly: String!, $snpid: String!, $limit: Int) {
+    snpAutocompleteQuery(assembly: $assembly, snpid: $snpid, limit: $limit) {
+      id
+      coordinates {
+        chromosome
+        start
+        end
+      }
+    }
+  }
+`, u = `
+  query Genes(
+      $name_prefix: [String!]
+      $idprefix: [String!]
+      $limit: Int
+      $assembly: String!
+      $version: Int
+      $includealiassearch: Boolean
+  ) {
+      gene(
+          name_prefix: $name_prefix
+          idprefix: $idprefix
+          limit: $limit
+          assembly: $assembly
+          orderby: "name"
+          version: $version
+          includealiassearch: $includealiassearch
+      ) {
+          id
+          name
+          coordinates {
+              chromosome
+              start
+              end
+          }
+          alias    
+      }
+  }
+`, _ = `
+  query iCREQuery($accession_prefix: [String!], $limit: Int) {
+      iCREQuery(accession_prefix: $accession_prefix, limit: $limit) {
+          rdhs
+          accession
+          celltypes
+          coordinates {
+              start
+              end
+              chromosome
+          }
+      }
+  }
+`, h = `
+  query cCREAutocompleteQuery(
+    $accession: [String!]
+    $accession_prefix: [String!]
+    $assembly: String!
+    $includeiCREs: Boolean
+    $limit: Int
+  ) {
+    cCREAutocompleteQuery(
+      includeiCREs: $includeiCREs
+      assembly: $assembly
+      limit: $limit
+      accession: $accession
+      accession_prefix: $accession_prefix
+    ) {
+      accession
+      isiCRE
+      coordinates {
+        chromosome
+        start
+        end
+      }
+    }
+  }
+`, C = `
+  query getv2v3CcreMapping($accessions: [String], $assembly: String!) {
+    ccreMappings: getv2cCREMappings(
+      v2_accession: $accessions
+      assembly: $assembly
+    ) {
+      input: v2_accession
+      input_latest_previous_version: ccre_version
+      input_region: v2_region
+      v4_match_or_intersecting: v4_accession
+      v4_region
+    }
+  }
+`, $ = `
+query getGWASStudyMetadata($limit: Int, $studyname_prefix: [String]){
+    getGWASStudiesMetadata(limit: $limit, studyname_prefix: $studyname_prefix )
+    {
+        studyid
+        author
+        disease_trait
+        has_enrichment_info
+        population
+        parent_terms
+        total_ld_blocks
+        ld_blocks_overlapping_ccres
+        overlapping_ccres
+    }
+}
+`, b = async (e, s, i, t) => (await fetch(i, {
+  method: "POST",
+  body: JSON.stringify({
+    query: _,
+    variables: {
+      accession_prefix: [e],
+      limit: s
+    }
+  }),
+  headers: {
+    "Content-Type": "application/json"
+  },
+  signal: t
+})).json(), v = async (e, s, i, t, a, p) => {
+  const r = e.length === 12;
+  return (await fetch(a, {
+    method: "POST",
+    body: JSON.stringify({
+      query: h,
+      variables: {
+        ...r ? {
+          accession: [e.toUpperCase()]
+        } : {
+          accession_prefix: [e]
+        },
+        assembly: s,
+        limit: i,
+        includeiCREs: t
+      }
+    }),
+    headers: {
+      "Content-Type": "application/json"
+    },
+    signal: p
+  })).json();
+}, R = async (e, s, i, t) => (await fetch(i, {
+  method: "POST",
+  body: JSON.stringify({
+    query: C,
+    variables: {
+      accessions: [e],
+      assembly: s
+    }
+  }),
+  headers: {
+    "Content-Type": "application/json"
+  },
+  signal: t
+})).json(), x = async (e, s, i, t, a, p) => {
+  let r = t ? typeof t == "number" ? [t] : t : [s === "GRCh38" ? 40 : 25];
+  r = r.sort((n, o) => o - n);
+  const m = await Promise.all(r.map((n) => fetch(a, {
+    method: "POST",
+    body: JSON.stringify({
+      query: u,
+      variables: {
+        assembly: s.toLowerCase(),
+        ...s.toLowerCase() === "mm10" && e.toUpperCase().startsWith("ENSMUSG") || s.toLowerCase() === "grch38" && e.toUpperCase().startsWith("ENSG") ? {
+          idprefix: e.split(".")[0]
+        } : {
+          name_prefix: e
+        },
+        version: n,
+        limit: i,
+        includealiassearch: !0
+      }
+    }),
+    headers: {
+      "Content-Type": "application/json"
+    },
+    signal: p
+  }).then((o) => o.json()))), l = /* @__PURE__ */ new Map();
+  return m.forEach((n, o) => {
+    (n.data.gene || []).forEach((c) => {
+      l.has(c.name) ? l.get(c.name).versions.push({
+        id: c.id,
+        version: r[o]
+      }) : l.set(c.name, {
+        gene: c,
+        versions: [{
+          id: c.id,
+          version: r[o]
+        }]
+      });
+    });
+  }), await Promise.all(Array.from(l.values()).map(async ({
+    gene: n,
+    versions: o
+  }) => {
+    const y = await f(n.name);
+    return {
+      ...n,
+      description: `${g(y || n.name)} ${n.alias ? `(${n.alias})` : ""}`,
+      versions: o
+    };
+  }));
+}, g = (e) => e.split(" ").map((s) => s.charAt(0).toUpperCase() + s.slice(1)).join(" ");
+async function f(e) {
+  try {
+    const i = await (await fetch("https://clinicaltables.nlm.nih.gov/api/ncbi_genes/v3/search?authenticity_token=&terms=" + e.toUpperCase())).json(), t = i[3] && i[3].filter((a) => a[3] === e.toUpperCase());
+    return t && t.length >= 1 ? t[0][4] : null;
+  } catch {
+    return null;
+  }
+}
+const T = async (e, s, i, t, a) => (await fetch(t, {
+  method: "POST",
+  body: JSON.stringify({
+    query: d,
+    variables: {
+      assembly: s.toLowerCase(),
+      snpid: e,
+      limit: i
+    }
+  }),
+  headers: {
+    "Content-Type": "application/json"
+  },
+  signal: a
+})).json(), O = async (e, s, i, t) => (await fetch(i, {
+  method: "POST",
+  body: JSON.stringify({
+    query: $,
+    variables: {
+      studyname_prefix: [e],
+      limit: s
+    }
+  }),
+  headers: {
+    "Content-Type": "application/json"
+  },
+  signal: t
+})).json();
 export {
-  s as default
+  h as CCRE_AUTOCOMPLETE_QUERY,
+  u as GENE_AUTOCOMPLETE_QUERY,
+  $ as GWAS_AUTOCOMPLETE_QUERY,
+  _ as ICRE_AUTOCOMPLETE_QUERY,
+  C as LEGACY_CCRE_QUERY,
+  d as SNP_AUTOCOMPLETE_QUERY,
+  v as getCCREs,
+  x as getGenes,
+  b as getICREs,
+  R as getLegacyCCREs,
+  T as getSNPs,
+  O as getStudys
 };
 //# sourceMappingURL=ui-components.es56.js.map

package/dist/ui-components.es56.js.map

@@ -1 +1 @@
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+{"version":3,"file":"ui-components.es56.js","sources":["../src/components/GenomeSearch/queries.ts"],"sourcesContent":["import { GenomeSearchProps } from \"./types\";\n\nexport const SNP_AUTOCOMPLETE_QUERY = `\n  query suggestions($assembly: String!, $snpid: String!, $limit: Int) {\n    snpAutocompleteQuery(assembly: $assembly, snpid: $snpid, limit: $limit) {\n      id\n      coordinates {\n        chromosome\n        start\n        end\n      }\n    }\n  }\n`;\n\nexport const GENE_AUTOCOMPLETE_QUERY = `\n  query Genes(\n      $name_prefix: [String!]\n      $idprefix: [String!]\n      $limit: Int\n      $assembly: String!\n      $version: Int\n      $includealiassearch: Boolean\n  ) {\n      gene(\n          name_prefix: $name_prefix\n          idprefix: $idprefix\n          limit: $limit\n          assembly: $assembly\n          orderby: \"name\"\n          version: $version\n          includealiassearch: $includealiassearch\n      ) {\n          id\n          name\n          coordinates {\n              chromosome\n              start\n              end\n          }\n          alias    \n      }\n  }\n`;\n\nexport const ICRE_AUTOCOMPLETE_QUERY = `\n  query iCREQuery($accession_prefix: [String!], $limit: Int) {\n      iCREQuery(accession_prefix: $accession_prefix, limit: $limit) {\n          rdhs\n          accession\n          celltypes\n          coordinates {\n              start\n              end\n              chromosome\n          }\n      }\n  }\n`;\n\nexport const CCRE_AUTOCOMPLETE_QUERY = `\n  query cCREAutocompleteQuery(\n    $accession: [String!]\n    $accession_prefix: [String!]\n    $assembly: String!\n    $includeiCREs: Boolean\n    $limit: Int\n  ) {\n    cCREAutocompleteQuery(\n      includeiCREs: $includeiCREs\n      assembly: $assembly\n      limit: $limit\n      accession: $accession\n      accession_prefix: $accession_prefix\n    ) {\n      accession\n      isiCRE\n      coordinates {\n        chromosome\n        start\n        end\n      }\n    }\n  }\n`;\n\nexport const LEGACY_CCRE_QUERY = `\n  query getv2v3CcreMapping($accessions: [String], $assembly: String!) {\n    ccreMappings: getv2cCREMappings(\n      v2_accession: $accessions\n      assembly: $assembly\n    ) {\n      input: v2_accession\n      input_latest_previous_version: ccre_version\n      input_region: v2_region\n      v4_match_or_intersecting: v4_accession\n      v4_region\n    }\n  }\n`\n\nexport const GWAS_AUTOCOMPLETE_QUERY = `\nquery getGWASStudyMetadata($limit: Int, $studyname_prefix: [String]){\n    getGWASStudiesMetadata(limit: $limit, studyname_prefix: $studyname_prefix )\n    {\n        studyid\n        author\n        disease_trait\n        has_enrichment_info\n        population\n        parent_terms\n        total_ld_blocks\n        ld_blocks_overlapping_ccres\n        overlapping_ccres\n    }\n}\n`;\n\nexport const getICREs = async (value: string, limit: number, url: string, signal?: AbortSignal) => {\n  const response = await fetch(url, {\n    method: \"POST\",\n    body: JSON.stringify({\n      query: ICRE_AUTOCOMPLETE_QUERY,\n      variables: {\n        accession_prefix: [value],\n        limit: limit,\n      },\n    }),\n    headers: { \"Content-Type\": \"application/json\" },\n    signal,\n  });\n  return response.json();\n};\n\nexport const getCCREs = async (value: string, assembly: GenomeSearchProps[\"assembly\"], limit: number, showiCREFlag: boolean, url: string, signal?: AbortSignal) => {\n  const isExactAccession = value.length === 12;\n  const response = await fetch(url, {\n    method: \"POST\",\n    body: JSON.stringify({\n      query: CCRE_AUTOCOMPLETE_QUERY,\n      variables: {\n        ...(isExactAccession\n          ? { accession: [value.toUpperCase()] }\n          : { accession_prefix: [value] }),\n        assembly,\n        limit,\n        includeiCREs: showiCREFlag,\n      },\n    }),\n    headers: { \"Content-Type\": \"application/json\" },\n    signal,\n  });\n  return response.json();\n};\n\nexport const getLegacyCCREs = async (value: string, assembly: GenomeSearchProps[\"assembly\"], url: string, signal?: AbortSignal) => {\n  const response = await fetch(url, {\n    method: \"POST\",\n    body: JSON.stringify({\n      query: LEGACY_CCRE_QUERY,\n      variables: {\n        accessions: [value],\n        assembly,\n      },\n    }),\n    headers: { \"Content-Type\": \"application/json\" },\n    signal,\n  });\n  return response.json();\n};\n\nexport const getGenes = async (\n  value: string,\n  assembly: GenomeSearchProps[\"assembly\"],\n  limit: number,\n  geneVersions: GenomeSearchProps[\"geneVersion\"],\n  url: string,\n  signal?: AbortSignal\n) => {\n  let versions = geneVersions\n    ? typeof geneVersions === \"number\"\n      ? [geneVersions]\n      : geneVersions\n    : [assembly === \"GRCh38\" ? 40 : 25];\n\n  // sort versions from high to low (prioritize newest versions in map)\n  versions = versions.sort((a, b) => b - a);\n\n  // Fetch genes for all versions\n  const versionResults = await Promise.all(\n  versions.map((version) =>\n    fetch(url, {\n      method: \"POST\",\n      body: JSON.stringify({\n        query: GENE_AUTOCOMPLETE_QUERY,\n        variables: {\n          assembly: assembly.toLowerCase(),\n          ...(\n            (\n              (assembly.toLowerCase() === \"mm10\" && value.toUpperCase().startsWith(\"ENSMUSG\")) ||\n              (assembly.toLowerCase() === \"grch38\" && value.toUpperCase().startsWith(\"ENSG\"))\n            )\n              ? { idprefix: value.split(\".\")[0] }\n              : { name_prefix: value }\n          ),\n          version: version,\n          limit: limit,\n          includealiassearch: true\n        },\n      }),\n      headers: { \"Content-Type\": \"application/json\" },\n      signal,\n    }).then((res) => res.json())\n  )\n);\n\n  // Combine and deduplicate results\n  const geneMap = new Map<string, { gene: any; versions: { id: string; version: number }[] }>();\n\n  versionResults.forEach((result, idx) => {\n    const genes = result.data.gene || [];\n    genes.forEach((gene: any) => {\n      if (!geneMap.has(gene.name)) {\n        geneMap.set(gene.name, { gene, versions: [{ id: gene.id, version: versions[idx] }] });\n      } else {\n        // if gene already exists, just add legacy versions to list.\n        const existing = geneMap.get(gene.name)!;\n        existing.versions.push({ id: gene.id, version: versions[idx] });\n      }\n    });\n  });\n\n  // Convert map to array and fetch descriptions\n  const out = await Promise.all(\n    Array.from(geneMap.values()).map(async ({ gene, versions }) => {\n      const description = await getDescription(gene.name);\n      return {\n        ...gene,\n        description: `${toTitleCase(description || gene.name)} ${gene.alias ? `(${gene.alias})` : ''}`,\n        versions,\n      };\n    })\n  );\n\n  return out;\n};\nconst toTitleCase = (str: string) =>\n  str\n    .split(\" \")\n    .map((word) => word.charAt(0).toUpperCase() + word.slice(1))\n    .join(\" \");\n\nasync function getDescription(name: string): Promise<string | null> {\n  try {\n    const response = await fetch(\n      \"https://clinicaltables.nlm.nih.gov/api/ncbi_genes/v3/search?authenticity_token=&terms=\" + name.toUpperCase()\n    );\n    const data = await response.json();\n    const matches = data[3] && data[3].filter((x: string[]) => x[3] === name.toUpperCase());\n    return matches && matches.length >= 1 ? matches[0][4] : null;\n  } catch {\n    return null;\n  }\n}\n\nexport const getSNPs = async (value: string, assembly: GenomeSearchProps[\"assembly\"], limit: number, url: string, signal?: AbortSignal) => {\n  const response = await fetch(url, {\n    method: \"POST\",\n    body: JSON.stringify({\n      query: SNP_AUTOCOMPLETE_QUERY,\n      variables: {\n        assembly: assembly.toLowerCase(),\n        snpid: value,\n        limit: limit,\n      },\n    }),\n    headers: { \"Content-Type\": \"application/json\" },\n    signal,\n  });\n  return response.json();\n};\n\nexport const getStudys = async (value: string, limit: number, url: string, signal?: AbortSignal) => {\n  const response = await fetch(url, {\n    method: \"POST\",\n    body: JSON.stringify({\n      query: GWAS_AUTOCOMPLETE_QUERY,\n      variables: {\n        studyname_prefix: [value],\n        limit,\n      },\n    }),\n    headers: { \"Content-Type\": \"application/json\" },\n    signal,\n  });\n\n  return 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