@synsci/cli-darwin-x64 1.1.70 → 1.1.72

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (339) hide show
  1. package/bin/skills/citation-management/SKILL.md +1109 -0
  2. package/bin/skills/citation-management/assets/bibtex_template.bib +264 -0
  3. package/bin/skills/citation-management/assets/citation_checklist.md +386 -0
  4. package/bin/skills/citation-management/references/bibtex_formatting.md +908 -0
  5. package/bin/skills/citation-management/references/citation_validation.md +794 -0
  6. package/bin/skills/citation-management/references/google_scholar_search.md +725 -0
  7. package/bin/skills/citation-management/references/metadata_extraction.md +870 -0
  8. package/bin/skills/citation-management/references/pubmed_search.md +839 -0
  9. package/bin/skills/citation-management/scripts/doi_to_bibtex.py +182 -0
  10. package/bin/skills/citation-management/scripts/extract_metadata.py +570 -0
  11. package/bin/skills/citation-management/scripts/format_bibtex.py +349 -0
  12. package/bin/skills/citation-management/scripts/search_google_scholar.py +251 -0
  13. package/bin/skills/citation-management/scripts/search_pubmed.py +348 -0
  14. package/bin/skills/citation-management/scripts/validate_citations.py +494 -0
  15. package/bin/skills/clinical-decision-support/README.md +129 -0
  16. package/bin/skills/clinical-decision-support/SKILL.md +506 -0
  17. package/bin/skills/clinical-decision-support/assets/biomarker_report_template.tex +380 -0
  18. package/bin/skills/clinical-decision-support/assets/clinical_pathway_template.tex +222 -0
  19. package/bin/skills/clinical-decision-support/assets/cohort_analysis_template.tex +359 -0
  20. package/bin/skills/clinical-decision-support/assets/color_schemes.tex +149 -0
  21. package/bin/skills/clinical-decision-support/assets/example_gbm_cohort.md +208 -0
  22. package/bin/skills/clinical-decision-support/assets/recommendation_strength_guide.md +328 -0
  23. package/bin/skills/clinical-decision-support/assets/treatment_recommendation_template.tex +529 -0
  24. package/bin/skills/clinical-decision-support/references/biomarker_classification.md +719 -0
  25. package/bin/skills/clinical-decision-support/references/clinical_decision_algorithms.md +604 -0
  26. package/bin/skills/clinical-decision-support/references/evidence_synthesis.md +840 -0
  27. package/bin/skills/clinical-decision-support/references/outcome_analysis.md +640 -0
  28. package/bin/skills/clinical-decision-support/references/patient_cohort_analysis.md +427 -0
  29. package/bin/skills/clinical-decision-support/references/treatment_recommendations.md +521 -0
  30. package/bin/skills/clinical-decision-support/scripts/biomarker_classifier.py +383 -0
  31. package/bin/skills/clinical-decision-support/scripts/build_decision_tree.py +417 -0
  32. package/bin/skills/clinical-decision-support/scripts/create_cohort_tables.py +509 -0
  33. package/bin/skills/clinical-decision-support/scripts/generate_survival_analysis.py +441 -0
  34. package/bin/skills/clinical-decision-support/scripts/validate_cds_document.py +326 -0
  35. package/bin/skills/clinical-reports/IMPLEMENTATION_SUMMARY.md +641 -0
  36. package/bin/skills/clinical-reports/README.md +236 -0
  37. package/bin/skills/clinical-reports/SKILL.md +1127 -0
  38. package/bin/skills/clinical-reports/assets/case_report_template.md +352 -0
  39. package/bin/skills/clinical-reports/assets/clinical_trial_csr_template.md +353 -0
  40. package/bin/skills/clinical-reports/assets/clinical_trial_sae_template.md +359 -0
  41. package/bin/skills/clinical-reports/assets/consult_note_template.md +305 -0
  42. package/bin/skills/clinical-reports/assets/discharge_summary_template.md +453 -0
  43. package/bin/skills/clinical-reports/assets/hipaa_compliance_checklist.md +395 -0
  44. package/bin/skills/clinical-reports/assets/history_physical_template.md +305 -0
  45. package/bin/skills/clinical-reports/assets/lab_report_template.md +309 -0
  46. package/bin/skills/clinical-reports/assets/pathology_report_template.md +249 -0
  47. package/bin/skills/clinical-reports/assets/quality_checklist.md +338 -0
  48. package/bin/skills/clinical-reports/assets/radiology_report_template.md +318 -0
  49. package/bin/skills/clinical-reports/assets/soap_note_template.md +253 -0
  50. package/bin/skills/clinical-reports/references/case_report_guidelines.md +570 -0
  51. package/bin/skills/clinical-reports/references/clinical_trial_reporting.md +693 -0
  52. package/bin/skills/clinical-reports/references/data_presentation.md +530 -0
  53. package/bin/skills/clinical-reports/references/diagnostic_reports_standards.md +629 -0
  54. package/bin/skills/clinical-reports/references/medical_terminology.md +588 -0
  55. package/bin/skills/clinical-reports/references/patient_documentation.md +744 -0
  56. package/bin/skills/clinical-reports/references/peer_review_standards.md +585 -0
  57. package/bin/skills/clinical-reports/references/regulatory_compliance.md +577 -0
  58. package/bin/skills/clinical-reports/scripts/check_deidentification.py +332 -0
  59. package/bin/skills/clinical-reports/scripts/compliance_checker.py +78 -0
  60. package/bin/skills/clinical-reports/scripts/extract_clinical_data.py +97 -0
  61. package/bin/skills/clinical-reports/scripts/format_adverse_events.py +97 -0
  62. package/bin/skills/clinical-reports/scripts/generate_report_template.py +149 -0
  63. package/bin/skills/clinical-reports/scripts/terminology_validator.py +126 -0
  64. package/bin/skills/clinical-reports/scripts/validate_case_report.py +323 -0
  65. package/bin/skills/clinical-reports/scripts/validate_trial_report.py +88 -0
  66. package/bin/skills/fireworks-ai/SKILL.md +665 -0
  67. package/bin/skills/generate-image/SKILL.md +178 -0
  68. package/bin/skills/generate-image/scripts/generate_image.py +254 -0
  69. package/bin/skills/groq/SKILL.md +347 -0
  70. package/bin/skills/hypothesis-generation/SKILL.md +293 -0
  71. package/bin/skills/hypothesis-generation/assets/FORMATTING_GUIDE.md +672 -0
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  73. package/bin/skills/hypothesis-generation/assets/hypothesis_report_template.tex +572 -0
  74. package/bin/skills/hypothesis-generation/references/experimental_design_patterns.md +329 -0
  75. package/bin/skills/hypothesis-generation/references/hypothesis_quality_criteria.md +198 -0
  76. package/bin/skills/hypothesis-generation/references/literature_search_strategies.md +622 -0
  77. package/bin/skills/latex-posters/README.md +417 -0
  78. package/bin/skills/latex-posters/SKILL.md +1602 -0
  79. package/bin/skills/latex-posters/assets/baposter_template.tex +257 -0
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  81. package/bin/skills/latex-posters/assets/poster_quality_checklist.md +358 -0
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  83. package/bin/skills/latex-posters/references/latex_poster_packages.md +745 -0
  84. package/bin/skills/latex-posters/references/poster_content_guide.md +748 -0
  85. package/bin/skills/latex-posters/references/poster_design_principles.md +806 -0
  86. package/bin/skills/latex-posters/references/poster_layout_design.md +900 -0
  87. package/bin/skills/latex-posters/scripts/review_poster.sh +214 -0
  88. package/bin/skills/literature-review/SKILL.md +641 -0
  89. package/bin/skills/literature-review/assets/review_template.md +412 -0
  90. package/bin/skills/literature-review/references/citation_styles.md +166 -0
  91. package/bin/skills/literature-review/references/database_strategies.md +455 -0
  92. package/bin/skills/literature-review/scripts/generate_pdf.py +184 -0
  93. package/bin/skills/literature-review/scripts/search_databases.py +310 -0
  94. package/bin/skills/literature-review/scripts/verify_citations.py +218 -0
  95. package/bin/skills/market-research-reports/SKILL.md +904 -0
  96. package/bin/skills/market-research-reports/assets/FORMATTING_GUIDE.md +428 -0
  97. package/bin/skills/market-research-reports/assets/market_report_template.tex +1380 -0
  98. package/bin/skills/market-research-reports/assets/market_research.sty +564 -0
  99. package/bin/skills/market-research-reports/references/data_analysis_patterns.md +548 -0
  100. package/bin/skills/market-research-reports/references/report_structure_guide.md +999 -0
  101. package/bin/skills/market-research-reports/references/visual_generation_guide.md +1077 -0
  102. package/bin/skills/market-research-reports/scripts/generate_market_visuals.py +472 -0
  103. package/bin/skills/markitdown/INSTALLATION_GUIDE.md +318 -0
  104. package/bin/skills/markitdown/LICENSE.txt +22 -0
  105. package/bin/skills/markitdown/OPENROUTER_INTEGRATION.md +359 -0
  106. package/bin/skills/markitdown/QUICK_REFERENCE.md +309 -0
  107. package/bin/skills/markitdown/README.md +184 -0
  108. package/bin/skills/markitdown/SKILL.md +486 -0
  109. package/bin/skills/markitdown/SKILL_SUMMARY.md +307 -0
  110. package/bin/skills/markitdown/assets/example_usage.md +463 -0
  111. package/bin/skills/markitdown/references/api_reference.md +399 -0
  112. package/bin/skills/markitdown/references/file_formats.md +542 -0
  113. package/bin/skills/markitdown/scripts/batch_convert.py +195 -0
  114. package/bin/skills/markitdown/scripts/convert_literature.py +262 -0
  115. package/bin/skills/markitdown/scripts/convert_with_ai.py +224 -0
  116. package/bin/skills/ml-paper-writing/SKILL.md +937 -0
  117. package/bin/skills/ml-paper-writing/references/checklists.md +361 -0
  118. package/bin/skills/ml-paper-writing/references/citation-workflow.md +562 -0
  119. package/bin/skills/ml-paper-writing/references/reviewer-guidelines.md +367 -0
  120. package/bin/skills/ml-paper-writing/references/sources.md +159 -0
  121. package/bin/skills/ml-paper-writing/references/writing-guide.md +476 -0
  122. package/bin/skills/ml-paper-writing/templates/README.md +251 -0
  123. package/bin/skills/ml-paper-writing/templates/aaai2026/README.md +534 -0
  124. package/bin/skills/ml-paper-writing/templates/aaai2026/aaai2026-unified-supp.tex +144 -0
  125. package/bin/skills/ml-paper-writing/templates/aaai2026/aaai2026-unified-template.tex +952 -0
  126. package/bin/skills/ml-paper-writing/templates/aaai2026/aaai2026.bib +111 -0
  127. package/bin/skills/ml-paper-writing/templates/aaai2026/aaai2026.bst +1493 -0
  128. package/bin/skills/ml-paper-writing/templates/aaai2026/aaai2026.sty +315 -0
  129. package/bin/skills/ml-paper-writing/templates/acl/README.md +50 -0
  130. package/bin/skills/ml-paper-writing/templates/acl/acl.sty +312 -0
  131. package/bin/skills/ml-paper-writing/templates/acl/acl_latex.tex +377 -0
  132. package/bin/skills/ml-paper-writing/templates/acl/acl_lualatex.tex +101 -0
  133. package/bin/skills/ml-paper-writing/templates/acl/acl_natbib.bst +1940 -0
  134. package/bin/skills/ml-paper-writing/templates/acl/anthology.bib.txt +26 -0
  135. package/bin/skills/ml-paper-writing/templates/acl/custom.bib +70 -0
  136. package/bin/skills/ml-paper-writing/templates/acl/formatting.md +326 -0
  137. package/bin/skills/ml-paper-writing/templates/colm2025/README.md +3 -0
  138. package/bin/skills/ml-paper-writing/templates/colm2025/colm2025_conference.bib +11 -0
  139. package/bin/skills/ml-paper-writing/templates/colm2025/colm2025_conference.bst +1440 -0
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  142. package/bin/skills/ml-paper-writing/templates/colm2025/colm2025_conference.tex +305 -0
  143. package/bin/skills/ml-paper-writing/templates/colm2025/fancyhdr.sty +485 -0
  144. package/bin/skills/ml-paper-writing/templates/colm2025/math_commands.tex +508 -0
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  146. package/bin/skills/ml-paper-writing/templates/iclr2026/fancyhdr.sty +485 -0
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  167. package/bin/skills/paper-2-web/SKILL.md +491 -0
  168. package/bin/skills/paper-2-web/references/installation.md +141 -0
  169. package/bin/skills/paper-2-web/references/paper2poster.md +346 -0
  170. package/bin/skills/paper-2-web/references/paper2video.md +305 -0
  171. package/bin/skills/paper-2-web/references/paper2web.md +187 -0
  172. package/bin/skills/paper-2-web/references/usage_examples.md +436 -0
  173. package/bin/skills/peer-review/SKILL.md +702 -0
  174. package/bin/skills/peer-review/references/calibration_guidelines.md +196 -0
  175. package/bin/skills/peer-review/references/common_issues.md +552 -0
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  177. package/bin/skills/peer-review/references/reporting_standards.md +290 -0
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  179. package/bin/skills/pptx-posters/SKILL.md +410 -0
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  185. package/bin/skills/research-grants/README.md +285 -0
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  187. package/bin/skills/research-grants/assets/budget_justification_template.md +453 -0
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  191. package/bin/skills/research-grants/references/darpa_guidelines.md +636 -0
  192. package/bin/skills/research-grants/references/doe_guidelines.md +586 -0
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1
+ % NeurIPS Conference Paper Template
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+ % For submission to Neural Information Processing Systems (NeurIPS)
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+ % Last updated: 2024
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+ % Note: Use the official neurips_2024.sty file from the conference website
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+
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+ \documentclass{article}
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+
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+ % Required packages (neurips_2024.sty provides most formatting)
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+ \usepackage{neurips_2024} % Official NeurIPS style file (download from conference site)
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+
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+ % Recommended packages
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+ \usepackage{amsmath}
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+ \usepackage{amssymb}
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+ \usepackage{amsthm}
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+ \usepackage{graphicx}
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+ \usepackage{algorithm}
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+ \usepackage{algorithmic}
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+ \usepackage{hyperref}
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+ \usepackage{url}
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+ \usepackage{booktabs} % For better tables
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+ \usepackage{multirow}
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+ \usepackage{microtype} % Improved typography
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+
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+ % Theorems, lemmas, etc.
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+ \newtheorem{theorem}{Theorem}
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+ \newtheorem{lemma}{Lemma}
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+ \newtheorem{proposition}{Proposition}
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+ \newtheorem{corollary}{Corollary}
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+ \newtheorem{definition}{Definition}
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+
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+ % Title and Authors
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+ \title{Your Paper Title: Concise and Descriptive \\ (Maximum Two Lines)}
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+
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+ % Authors - ANONYMIZED for initial submission
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+ % For initial submission (double-blind review):
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+ \author{
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+ Anonymous Authors \\
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+ Anonymous Institution(s) \\
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+ }
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+
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+ % For camera-ready version (after acceptance):
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+ % \author{
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+ % First Author \\
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+ % Department of Computer Science \\
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+ % University Name \\
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+ % City, State, Postal Code \\
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+ % \texttt{first.author@university.edu} \\
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+ % \And
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+ % Second Author \\
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+ % Company/Institution Name \\
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+ % Address \\
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+ % \texttt{second.author@company.com} \\
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+ % \And
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+ % Third Author \\
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+ % Institution \\
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+ % \texttt{third.author@institution.edu}
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+ % }
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+
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+ \begin{document}
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+
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+ \maketitle
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+
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+ \begin{abstract}
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+ Write a concise abstract (150-250 words) summarizing your contributions. The abstract should clearly state: (1) the problem you address, (2) your approach/method, (3) key results/findings, and (4) significance/implications. Make it accessible to a broad machine learning audience.
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+ \end{abstract}
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+
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+ \section{Introduction}
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+ \label{sec:introduction}
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+
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+ Introduce the problem you're addressing and its significance in machine learning or AI. Motivate why this problem is important and challenging.
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+
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+ \subsection{Background and Motivation}
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+ Provide necessary background for understanding your work. Explain the gap in current methods or knowledge.
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+
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+ \subsection{Contributions}
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+ Clearly state your main contributions as a bulleted list:
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+ \begin{itemize}
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+ \item First contribution: e.g., "We propose a novel architecture for..."
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+ \item Second contribution: e.g., "We provide theoretical analysis showing..."
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+ \item Third contribution: e.g., "We demonstrate state-of-the-art performance on..."
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+ \end{itemize}
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+
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+ \subsection{Paper Organization}
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+ Briefly describe the structure of the remainder of the paper.
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+
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+ \section{Related Work}
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+ \label{sec:related}
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+
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+ Discuss relevant prior work and how your work differs. Organize by themes or approaches rather than chronologically. Be fair and accurate in describing others' work.
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+
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+ Cite key papers \cite{lecun2015deep, vaswani2017attention, devlin2019bert} and explain how your work builds upon or differs from them.
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+
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+ \section{Problem Formulation}
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+ \label{sec:problem}
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+
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+ Formally define the problem you're solving. Include mathematical notation and definitions.
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+
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+ \subsection{Notation}
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+ Define your notation clearly. For example:
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+ \begin{itemize}
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+ \item $\mathcal{X}$: input space
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+ \item $\mathcal{Y}$: output space
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+ \item $f: \mathcal{X} \rightarrow \mathcal{Y}$: function to learn
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+ \item $\mathcal{D} = \{(x_i, y_i)\}_{i=1}^n$: training dataset
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+ \end{itemize}
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+
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+ \subsection{Objective}
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+ State your learning objective formally, e.g.:
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+ \begin{equation}
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+ \min_{\theta} \mathbb{E}_{(x,y) \sim \mathcal{D}} \left[ \mathcal{L}(f_\theta(x), y) \right]
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+ \end{equation}
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+ where $\mathcal{L}$ is the loss function and $\theta$ are model parameters.
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+
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+ \section{Method}
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+ \label{sec:method}
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+
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+ Describe your proposed method in detail. This is the core technical contribution of your paper.
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+
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+ \subsection{Model Architecture}
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+ Describe the architecture of your model with sufficient detail for reproduction. Include figures if helpful.
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+
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+ \begin{figure}[t]
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+ \centering
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+ % \includegraphics[width=0.8\textwidth]{architecture.pdf}
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+ \caption{Model architecture diagram. Describe the key components and data flow. Use colorblind-safe colors.}
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+ \label{fig:architecture}
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+ \end{figure}
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+
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+ \subsection{Training Procedure}
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+ Explain how you train the model, including:
131
+ \begin{algorithm}[t]
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+ \caption{Training Algorithm}
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+ \label{alg:training}
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+ \begin{algorithmic}[1]
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+ \STATE \textbf{Input:} Training data $\mathcal{D}$, learning rate $\alpha$
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+ \STATE \textbf{Output:} Trained parameters $\theta$
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+ \STATE Initialize $\theta$ randomly
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+ \FOR{epoch $= 1$ to $T$}
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+ \FOR{batch $(x, y)$ in $\mathcal{D}$}
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+ \STATE Compute loss: $\mathcal{L} = \mathcal{L}(f_\theta(x), y)$
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+ \STATE Update: $\theta \leftarrow \theta - \alpha \nabla_\theta \mathcal{L}$
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+ \ENDFOR
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+ \ENDFOR
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+ \RETURN $\theta$
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+ \end{algorithmic}
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+ \end{algorithm}
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+
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+ \subsection{Key Components}
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+ Describe key technical innovations or components in detail.
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+
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+ \section{Theoretical Analysis}
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+ \label{sec:theory}
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+
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+ If applicable, provide theoretical analysis of your method.
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+
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+ \begin{theorem}
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+ \label{thm:main}
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+ State your main theoretical result here.
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+ \end{theorem}
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+
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+ \begin{proof}
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+ Provide proof or sketch of proof. Full proofs can go in the appendix.
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+ \end{proof}
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+
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+ \section{Experiments}
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+ \label{sec:experiments}
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+
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+ Describe your experimental setup and results.
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+
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+ \subsection{Experimental Setup}
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+ \textbf{Datasets:} Describe datasets used (e.g., ImageNet, CIFAR-10, etc.).
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+
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+ \textbf{Baselines:} List baseline methods for comparison.
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+
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+ \textbf{Implementation Details:} Provide implementation details including hyperparameters, hardware, training time.
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+
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+ \textbf{Evaluation Metrics:} Define metrics used (accuracy, F1, AUC, etc.).
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+
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+ \subsection{Main Results}
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+ Present your main experimental results.
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+
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+ \begin{table}[t]
183
+ \centering
184
+ \caption{Performance comparison on benchmark datasets. Bold indicates best performance. Results reported as mean ± std over 3 runs.}
185
+ \label{tab:main_results}
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+ \begin{tabular}{lcccc}
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+ \toprule
188
+ Method & Dataset 1 & Dataset 2 & Dataset 3 & Average \\
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+ \midrule
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+ Baseline 1 & 85.3 ± 0.5 & 72.1 ± 0.8 & 90.2 ± 0.3 & 82.5 \\
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+ Baseline 2 & 87.2 ± 0.4 & 74.5 ± 0.6 & 91.1 ± 0.5 & 84.3 \\
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+ \textbf{Our Method} & \textbf{91.7 ± 0.3} & \textbf{79.8 ± 0.5} & \textbf{94.3 ± 0.2} & \textbf{88.6} \\
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+ \bottomrule
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+ \end{tabular}
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+ \end{table}
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+
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+ \subsection{Ablation Studies}
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+ Conduct ablation studies to understand which components contribute to performance.
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+
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+ \subsection{Analysis}
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+ Provide deeper analysis of results, failure cases, limitations, etc.
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+
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+ \section{Discussion}
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+ \label{sec:discussion}
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+
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+ Discuss your findings, limitations, and broader implications.
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+
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+ \subsection{Limitations}
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+ Honestly acknowledge limitations of your work.
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+
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+ \subsection{Broader Impacts}
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+ Discuss potential positive and negative societal impacts (required by NeurIPS).
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+
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+ \section{Conclusion}
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+ \label{sec:conclusion}
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+
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+ Summarize your main contributions and findings. Suggest future research directions.
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+
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+ % Acknowledgments (add after acceptance, not in submission version)
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+ \section*{Acknowledgments}
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+ Thank collaborators, funding sources (with grant numbers), and compute resources. Not included in double-blind submission.
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+
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+ % References
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+ \bibliographystyle{plainnat} % or other NeurIPS-compatible style
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+ \bibliography{references} % Your .bib file
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+
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+ % Appendix (optional, unlimited pages)
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+ \appendix
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+
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+ \section{Additional Proofs}
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+ \label{app:proofs}
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+
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+ Provide full proofs of theorems here.
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+
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+ \section{Additional Experimental Results}
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+ \label{app:experiments}
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+
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+ Include additional experiments, more ablations, qualitative results, etc.
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+
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+ \section{Hyperparameters}
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+ \label{app:hyperparameters}
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+
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+ List all hyperparameters used in experiments for reproducibility.
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+
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+ \begin{table}[h]
246
+ \centering
247
+ \caption{Hyperparameters used in all experiments}
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+ \begin{tabular}{ll}
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+ \toprule
250
+ Hyperparameter & Value \\
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+ \midrule
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+ Learning rate & 0.001 \\
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+ Batch size & 64 \\
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+ Optimizer & Adam \\
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+ Weight decay & 0.0001 \\
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+ Epochs & 100 \\
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+ \bottomrule
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+ \end{tabular}
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+ \end{table}
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+
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+ \section{Code and Data}
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+ \label{app:code}
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+
264
+ Provide links to code repository (anonymized for review, e.g., anonymous GitHub):
265
+ \begin{itemize}
266
+ \item Code: \url{https://anonymous.4open.science/r/project-XXXX}
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+ \item Data: Available upon request / at [repository]
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+ \end{itemize}
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+
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+ \end{document}
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+
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+ % Notes for Authors:
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+ % 1. Main paper: 8 pages maximum (excluding references and appendix)
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+ % 2. References: unlimited pages
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+ % 3. Appendix: unlimited pages (reviewed at discretion of reviewers)
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+ % 4. Use double-blind anonymization for initial submission
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+ % 5. Include broader impact statement
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+ % 6. Code submission strongly encouraged (anonymous for review)
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+ % 7. Use official neurips_2024.sty file (download from NeurIPS website)
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+ % 8. Font: Times, 10pt (enforced by style file)
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+ % 9. Figures should be colorblind-friendly
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+ % 10. Ensure reproducibility: report seeds, hyperparameters, dataset splits
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+
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+ % PLOS ONE Article Template
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+ % For submission to PLOS ONE and other PLOS journals
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+ % Last updated: 2024
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+
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+ \documentclass[10pt,letterpaper]{article}
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+
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+ % Packages
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+ \usepackage[top=0.85in,left=2.75in,footskip=0.75in]{geometry}
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+ \usepackage{amsmath,amssymb}
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+ \usepackage{changepage}
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+ \usepackage[utf8]{inputenc}
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+ \usepackage{textcomp,marvosym}
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+ \usepackage{cite}
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+ \usepackage{nameref,hyperref}
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+ \usepackage[right]{lineno}
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+ \usepackage{microtype}
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+ \usepackage{graphicx}
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+ \usepackage[table]{xcolor}
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+ \usepackage{array}
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+ \usepackage{authblk}
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+
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+ % Line numbering
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+ \linenumbers
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+
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+ % Set up authblk for PLOS format
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+ \renewcommand\Authfont{\fontsize{12}{14}\selectfont}
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+ \renewcommand\Affilfont{\fontsize{9}{11}\selectfont}
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+
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+ % Title
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+ \title{Your Article Title Here: Concise and Descriptive}
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+
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+ % Authors and Affiliations
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+ \author[1]{First Author}
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+ \author[1,2]{Second Author}
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+ \author[2,$\dagger$]{Third Author}
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+
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+ \affil[1]{Department of Biology, University Name, City, State, Country}
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+ \affil[2]{Institute of Research, Institution Name, City, Country}
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+
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+ % Corresponding author
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+ \affil[$\dagger$]{Corresponding author. E-mail: [email protected]}
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+
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+ \date{}
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+
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+ \begin{document}
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+
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+ \maketitle
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+
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+ % Abstract
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+ \begin{abstract}
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+ \noindent
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+ Write a structured or unstructured abstract of 250-300 words. The abstract should be accessible to a broad readership and should clearly state: (1) background/rationale, (2) objectives, (3) methods, (4) principal findings with key data, and (5) conclusions and significance. Do not include citations in the abstract.
53
+ \end{abstract}
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+
55
+ % Introduction
56
+ \section*{Introduction}
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+
58
+ Provide background and context for your study. The introduction should:
59
+ \begin{itemize}
60
+ \item Present the rationale for your study
61
+ \item Clearly state what is currently known about the topic
62
+ \item Identify the knowledge gap your study addresses
63
+ \item State your research objectives or hypotheses
64
+ \item Explain the significance of the research
65
+ \end{itemize}
66
+
67
+ Review relevant literature \cite{smith2023,jones2022}, setting your work in context.
68
+
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+ State your main research question or objective at the end of the introduction.
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+
71
+ % Materials and Methods
72
+ \section*{Materials and Methods}
73
+
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+ Provide sufficient detail to allow reproduction of your work.
75
+
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+ \subsection*{Study Design}
77
+ Describe the overall study design (e.g., prospective cohort, randomized controlled trial, observational study, etc.).
78
+
79
+ \subsection*{Participants/Samples}
80
+ Describe your study population, sample collection, or experimental subjects:
81
+ \begin{itemize}
82
+ \item Sample size and how it was determined (power analysis)
83
+ \item Inclusion and exclusion criteria
84
+ \item Demographic information
85
+ \item For animal studies: species, strain, age, sex, housing conditions
86
+ \end{itemize}
87
+
88
+ \subsection*{Procedures}
89
+ Detail all experimental procedures, measurements, and interventions. Include:
90
+ \begin{itemize}
91
+ \item Equipment and reagents (with manufacturer, catalog numbers)
92
+ \item Protocols and procedures (step-by-step if novel)
93
+ \item Controls used
94
+ \item Blinding and randomization (if applicable)
95
+ \end{itemize}
96
+
97
+ \subsection*{Data Collection}
98
+ Describe how data were collected, including instruments, assays, and measurements.
99
+
100
+ \subsection*{Statistical Analysis}
101
+ Clearly describe statistical methods used:
102
+ \begin{itemize}
103
+ \item Software and version (e.g., R 4.3.0, Python 3.9 with scipy 1.9.0)
104
+ \item Statistical tests performed (e.g., t-tests, ANOVA, regression)
105
+ \item Significance level ($\alpha$, typically 0.05)
106
+ \item Corrections for multiple testing
107
+ \item Sample size justification
108
+ \end{itemize}
109
+
110
+ \subsection*{Ethical Approval}
111
+ Include relevant ethical approval statements:
112
+ \begin{itemize}
113
+ \item Human subjects: IRB approval, protocol number, consent procedures
114
+ \item Animal research: IACUC approval, protocol number, welfare considerations
115
+ \item Field studies: Permits and permissions
116
+ \end{itemize}
117
+
118
+ Example: "This study was approved by the Institutional Review Board of University Name (Protocol \#12345). All participants provided written informed consent."
119
+
120
+ % Results
121
+ \section*{Results}
122
+
123
+ Present your findings in a logical sequence. Refer to figures and tables as you describe results. Do not interpret results in this section (save for Discussion).
124
+
125
+ \subsection*{First Major Finding}
126
+ Describe your first key result. Statistical results should include effect sizes and confidence intervals in addition to p-values.
127
+
128
+ As shown in Figure~\ref{fig:results1}, we observed a significant increase in [outcome variable] (mean $\pm$ SD: 45.2 $\pm$ 8.3 vs. 32.1 $\pm$ 6.9; t = 7.42, df = 48, p < 0.001).
129
+
130
+ \begin{figure}[!ht]
131
+ \centering
132
+ % \includegraphics[width=0.75\textwidth]{figure1.png}
133
+ \caption{{\bf Figure 1. Title of first figure.}
134
+ Detailed figure legend describing what is shown. Include: (A) Description of panel A. (B) Description of panel B. Sample sizes (n), error bars represent [SD, SEM, 95\% CI], and statistical significance indicated by asterisks (* p < 0.05, ** p < 0.01, *** p < 0.001). Statistical test used should be stated.}
135
+ \label{fig:results1}
136
+ \end{figure}
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+
138
+ \subsection*{Second Major Finding}
139
+ Describe your second key result, referencing Table~\ref{tab:results1}.
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+
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+ \begin{table}[!ht]
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+ \centering
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+ \caption{{\bf Table 1. Title of table.}}
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+ \label{tab:results1}
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+ \begin{tabular}{lccc}
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+ \hline
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+ \textbf{Condition} & \textbf{Measurement 1} & \textbf{Measurement 2} & \textbf{p-value} \\
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+ \hline
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+ Control & 25.3 $\pm$ 3.1 & 48.2 $\pm$ 5.4 & -- \\
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+ Treatment A & 32.7 $\pm$ 2.8 & 55.1 $\pm$ 4.9 & 0.003 \\
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+ Treatment B & 41.2 $\pm$ 3.5 & 62.8 $\pm$ 6.2 & < 0.001 \\
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+ \hline
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+ \end{tabular}
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+ \begin{flushleft}
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+ Values shown as mean $\pm$ standard deviation (n = 20 per group). P-values from one-way ANOVA with Tukey's post-hoc test comparing to control.
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+ \end{flushleft}
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+ \end{table}
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+
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+ \subsection*{Additional Results}
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+ Present additional findings as needed.
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+
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+ % Discussion
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+ \section*{Discussion}
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+
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+ Interpret your results and place them in the context of existing literature.
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+
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+ \subsection*{Principal Findings}
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+ Summarize your main findings concisely.
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+
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+ \subsection*{Interpretation}
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+ Interpret your findings and explain their significance. How do they advance understanding of the topic? Compare and contrast with previous studies \cite{brown2021,williams2020}.
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+
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+ \subsection*{Strengths and Limitations}
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+ Discuss both strengths and limitations of your study honestly:
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+
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+ \textbf{Strengths:}
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+ \begin{itemize}
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+ \item Large sample size with adequate statistical power
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+ \item Rigorous methodology with appropriate controls
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+ \item Novel approach or finding
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+ \end{itemize}
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+
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+ \textbf{Limitations:}
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+ \begin{itemize}
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+ \item Cross-sectional design limits causal inference
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+ \item Generalizability may be limited to [specific population]
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+ \item Potential confounding variables not measured
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+ \end{itemize}
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+
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+ \subsection*{Implications}
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+ Discuss the practical or theoretical implications of your findings.
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+
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+ \subsection*{Future Directions}
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+ Suggest directions for future research.
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+
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+ % Conclusions
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+ \section*{Conclusions}
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+
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+ Provide a concise conclusion summarizing the main findings and their significance. Avoid repeating the abstract.
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+
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+ % Acknowledgments
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+ \section*{Acknowledgments}
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+
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+ Acknowledge individuals who contributed but do not meet authorship criteria, technical assistance, and writing assistance. Example: "We thank Dr. Jane Doe for technical assistance with microscopy and Dr. John Smith for helpful discussions."
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+
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+ % References
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+ \section*{References}
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+
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+ % Using BibTeX
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+ \bibliographystyle{plos2015}
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+ \bibliography{references}
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+
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+ % Or manually formatted (Vancouver style, numbered):
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+ \begin{thebibliography}{99}
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+
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+ \bibitem{smith2023}
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+ Smith JD, Johnson ML, Williams KR. Title of article. Journal Abbrev. 2023;45(3):301-318. doi:10.1371/journal.pone.1234567.
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+
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+ \bibitem{jones2022}
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+ Jones AB, Brown CD. Another article title. PLoS ONE. 2022;17(8):e0234567. doi:10.1371/journal.pone.0234567.
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+
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+ \bibitem{brown2021}
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+ Brown EF, Davis GH, Wilson IJ, Taylor JK. Comprehensive study title. Nat Commun. 2021;12:1234. doi:10.1038/s41467-021-12345-6.
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+
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+ \bibitem{williams2020}
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+ Williams LM, Anderson NO. Previous work on topic. Science. 2020;368(6489):456-460. doi:10.1126/science.abc1234.
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+
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+ \end{thebibliography}
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+
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+ % Supporting Information
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+ \section*{Supporting Information}
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+
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+ List all supporting information files (captions provided separately during submission):
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+
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+ \paragraph{S1 Fig.}
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+ \textbf{Title of supplementary figure 1.} Brief description.
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+
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+ \paragraph{S2 Fig.}
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+ \textbf{Title of supplementary figure 2.} Brief description.
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+
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+ \paragraph{S1 Table.}
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+ \textbf{Title of supplementary table 1.} Brief description.
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+
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+ \paragraph{S1 Dataset.}
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+ \textbf{Raw data.} Complete dataset used in analysis (CSV format).
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+
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+ \paragraph{S1 File.}
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+ \textbf{Supplementary methods.} Additional methodological details.
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+
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+ % Author Contributions (CRediT taxonomy recommended)
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+ \section*{Author Contributions}
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+
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+ Use CRediT (Contributor Roles Taxonomy):
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+ \begin{itemize}
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+ \item \textbf{Conceptualization:} FA, SA
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+ \item \textbf{Data curation:} FA
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+ \item \textbf{Formal analysis:} FA, SA
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+ \item \textbf{Funding acquisition:} TA
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+ \item \textbf{Investigation:} FA, SA
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+ \item \textbf{Methodology:} FA, SA, TA
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+ \item \textbf{Project administration:} TA
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+ \item \textbf{Resources:} TA
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+ \item \textbf{Software:} FA
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+ \item \textbf{Supervision:} TA
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+ \item \textbf{Validation:} FA, SA
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+ \item \textbf{Visualization:} FA
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+ \item \textbf{Writing – original draft:} FA
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+ \item \textbf{Writing – review \& editing:} FA, SA, TA
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+ \end{itemize}
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+
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+ (FA = First Author, SA = Second Author, TA = Third Author)
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+
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+ % Data Availability Statement (REQUIRED)
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+ \section*{Data Availability}
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+
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+ Choose one of the following:
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+
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+ \textbf{Option 1 (Public repository):}
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+ All data are available in the [repository name] repository at [URL/DOI].
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+
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+ \textbf{Option 2 (Supporting Information):}
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+ All relevant data are within the paper and its Supporting Information files.
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+
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+ \textbf{Option 3 (Available on request):}
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+ Data cannot be shared publicly because of [reason]. Data are available from the [institution/contact] (contact via [email]) for researchers who meet the criteria for access to confidential data.
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+
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+ \textbf{Option 4 (Third-party):}
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+ Data are available from [third party] (contact: [details]) for researchers who meet criteria for access.
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+
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+ % Funding Statement (REQUIRED)
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+ \section*{Funding}
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+
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+ State all funding sources including grant numbers. If no funding, state "The authors received no specific funding for this work."
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+
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+ Example: "This work was supported by the National Science Foundation (NSF) [grant number 123456 to TA] and the National Institutes of Health (NIH) [grant number R01-234567 to TA]. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."
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+
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+ % Competing Interests (REQUIRED)
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+ \section*{Competing Interests}
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+
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+ Declare any financial or non-financial competing interests. If none, state: "The authors have declared that no competing interests exist."
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+
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+ If competing interests exist, declare them explicitly: "Author TA is a consultant for Company X. This does not alter our adherence to PLOS ONE policies on sharing data and materials."
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+
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+ \end{document}
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+
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+ % Notes for Authors:
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+ % 1. PLOS ONE has no length limit - be concise but thorough
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+ % 2. Use Vancouver style for citations [1], [2], [3]
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+ % 3. Figures: TIFF or EPS format, 300-600 dpi
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+ % 4. All data must be made available (data availability statement required)
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+ % 5. Include line numbers for review
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+ % 6. PLOS ONE focuses on scientific rigor, not novelty or impact
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+ % 7. Reporting guidelines encouraged (CONSORT, STROBE, PRISMA, etc.)
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+ % 8. Ethical approval required for human/animal studies
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+ % 9. All authors must agree to submission
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+ % 10. Submit via PLOS online submission system
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+