@sjcrh/proteinpaint-client 2.225.0 → 2.227.0

package/dist/geneVariant-PWMXP6H4.js

@@ -0,0 +1,289 @@
+import {
+  excludeFilterByTag,
+  fillGroupsetGroups,
+  filterInit,
+  filterPromptInit,
+  getDtTermValues,
+  getNormalRoot,
+  getPillNameDefault,
+  make_radios,
+  renderTable,
+  vocabInit
+} from "./chunk-YBXQBSFY.js";
+import "./chunk-HJ6L54YS.js";
+import "./chunk-QKVKQD6S.js";
+import "./chunk-CNFTQSNE.js";
+import "./chunk-DOC3HBOV.js";
+import "./chunk-TVJOSRCH.js";
+import "./chunk-3CIL7KH7.js";
+import "./chunk-T4XPCSLP.js";
+import "./chunk-VVWZ4BOI.js";
+import "./chunk-W5J3LTYS.js";
+import "./chunk-2IAELUCN.js";
+import {
+  getDtsFromGroups,
+  getTermLabelSuffix
+} from "./chunk-CFYWQJ7F.js";
+import {
+  getColors
+} from "./chunk-2N345NXD.js";
+import "./chunk-HBNB5TRH.js";
+import "./chunk-PF4DSFDR.js";
+import "./chunk-4OLM3KSB.js";
+import "./chunk-PWYMHUXY.js";
+import "./chunk-TLT4YIG3.js";
+import "./chunk-5R63Q5KH.js";
+import "./chunk-I6Y4O3RR.js";
+import {
+  rgb
+} from "./chunk-Q5RDQNIT.js";
+import "./chunk-HS5PO5ZQ.js";
+
+// termsetting/handlers/geneVariant.ts
+var colorScale = getColors(5);
+function getHandler(self) {
+  return {
+    getPillName(d) {
+      let name = d.name;
+      if (!name) {
+        if (d.genes) name = d.genes.map((g) => g.gene).join(", ");
+        else if (d.chr) name = `${d.chr}:${d.start}-${d.stop}`;
+        else name = d.id || "geneVariant";
+      }
+      return getPillNameDefault(self, { name });
+    },
+    getPillStatus() {
+      let text;
+      const q = self.q;
+      if (q.type == "predefined-groupset") {
+        const groupsetting = self.term.groupsetting;
+        if (!groupsetting?.lst?.length) throw "no predefined groupsets found";
+        const groupset = groupsetting.lst[q.predefined_groupset_idx];
+        text = groupset.name;
+      } else if (q.type == "custom-groupset") {
+        const n = q.customset.groups.length;
+        text = `Divided into ${n} groups`;
+      } else {
+        text = "any variant class";
+      }
+      text += getTermLabelSuffix(self.term, q);
+      return { text };
+    },
+    async showEditMenu(div) {
+      await makeEditMenu(self, div);
+    }
+  };
+}
+async function makeEditMenu(self, _div) {
+  delete self.groups;
+  const div = _div.append("div").style("margin", "10px");
+  div.append("div").style("font-size", "1.2rem").text(self.term.name);
+  const optsDiv = div.append("div").style("margin-top", "10px").style("margin-bottom", "1px");
+  const groupsDiv = div.append("div").style("display", "none").style("margin", "10px").style("vertical-align", "top");
+  optsDiv.append("div").style("font-weight", "bold").text("Group samples");
+  const q = self.q;
+  const isGroupset = q.type == "predefined-groupset" || q.type == "custom-groupset";
+  make_radios({
+    holder: optsDiv,
+    options: [
+      { label: "No sample grouping", value: "noGroup", checked: !isGroupset },
+      { label: "Assign samples to groups", value: "group", checked: isGroupset }
+    ],
+    callback: async (v) => {
+      if (v == "group") {
+        if (q.type == "values") Object.assign(q, { type: "custom-groupset", customset: { groups: [] } });
+        await makeGroupUI(self, groupsDiv);
+      } else {
+        clearGroupset(self);
+        groupsDiv.style("display", "none");
+      }
+    }
+  });
+  if (isGroupset) await makeGroupUI(self, groupsDiv);
+  if (self.usecase?.detail && ["term", "term0", "term2"].includes(self.usecase.detail) || self.opts.geneVariantEditMenuOnlyGrp) {
+    optsDiv.style("display", "none");
+    groupsDiv.style("margin", "0px");
+  }
+  div.append("div").style("margin-top", "25px").append("button").attr("data-testid", "sjpp-ts-gv-editui-applyBtn").text("Apply").on("click", () => {
+    const q2 = self.q;
+    if (q2.type == "predefined-groupset" || q2.type == "custom-groupset") {
+      if (!self.groups?.length) {
+        window.alert("Samples must be assigned to at least one group.");
+        return;
+      } else {
+        const dtLst = getDtsFromGroups(self.groups);
+        Object.assign(q2, { type: "custom-groupset", customset: { groups: self.groups }, dtLst });
+        self.vocabApi.rememberGvQ?.(self.term, q2);
+      }
+    } else {
+      if (q2.type != "values") throw `q.type must be 'values'`;
+    }
+    self.api.runCallback();
+  });
+}
+async function makeGroupUI(self, div) {
+  div.style("display", "block");
+  div.selectAll("*").remove();
+  div.append("div").style("margin", "15px 0px").text(
+    "Group samples by mutation status. Samples are assigned to first possible group. Only tested samples are considered."
+  );
+  const filterTableDiv = div.append("div");
+  const addNewGroupBtnHolder = div.append("div");
+  const q = self.q;
+  if (q.type != "predefined-groupset" && q.type != "custom-groupset") throw "unexpected q.type";
+  if (!self.groups) {
+    let groupset;
+    if (q.type == "predefined-groupset") {
+      const groupsetting = self.term.groupsetting;
+      if (!groupsetting.lst?.length) throw "no predefined groupsets found";
+      await fillGroupsetGroups(self.term, q.predefined_groupset_idx, self.vocabApi, q.origins);
+      groupset = groupsetting.lst[q.predefined_groupset_idx];
+    } else {
+      groupset = q.customset;
+    }
+    if (!groupset) throw "groupset is missing";
+    if (!Array.isArray(groupset.groups)) throw "groupset.groups is not array";
+    self.groups = structuredClone(groupset.groups);
+  }
+  const dtTerms = structuredClone(self.term.childTerms);
+  for (const dtTerm of dtTerms) {
+    await getDtTermValues(dtTerm, self.filter, self.vocabApi, { withMnames: true });
+  }
+  const vocabApi = vocabInit({ vocab: { terms: dtTerms } });
+  vocabApi.termdbConfig = {
+    queries: self.vocabApi.termdbConfig.queries,
+    assayAvailability: self.vocabApi.termdbConfig.assayAvailability
+  };
+  vocabApi.vocab.genome = self.vocabApi.vocab?.genome;
+  const filterPrompt = await filterPromptInit({
+    holder: addNewGroupBtnHolder,
+    vocabApi,
+    emptyLabel: "Add group",
+    header_mode: "hide_search",
+    callback: (f) => {
+      const filter2 = getNormalRoot(f);
+      addNewGroup(filter2, self.groups);
+      makeGroupUI(self, div);
+    },
+    debug: self.opts.debug
+  });
+  const filter = structuredClone(self.filter);
+  filterPrompt.main(excludeFilterByTag(filter, "cohortFilter"));
+  if (!self.groups.length) {
+    filterTableDiv.style("display", "none");
+    return;
+  }
+  filterTableDiv.style("display", "").selectAll("*").remove();
+  const tableArg = {
+    div: filterTableDiv,
+    columns: [
+      {},
+      // blank column to add delete buttons
+      {
+        label: "NAME",
+        editCallback: async (i, cell) => {
+          const newName = cell.value;
+          const index = self.groups.findIndex((group) => group.name == newName);
+          if (index != -1) {
+            alert(`Group named ${newName} already exists`);
+            makeGroupUI(self, div);
+          } else {
+            self.groups[i].name = newName;
+            makeGroupUI(self, div);
+          }
+        }
+      },
+      {
+        label: "COLOR",
+        editCallback: async (i, cell) => {
+          self.groups[i].color = cell.color;
+          makeGroupUI(self, div);
+        }
+      },
+      //{ label: '#SAMPLE' }, // will re-enable when filtered sample count can be supported for gdc
+      { label: "FILTER" }
+    ],
+    rows: [],
+    striped: false,
+    // no alternating row bg color so delete button appears more visible
+    showLines: false
+  };
+  for (const g of self.groups) {
+    tableArg.rows.push([
+      {},
+      // blank cell to add delete button
+      { value: g.name },
+      // to allow click to show <input>
+      { color: g.color },
+      // { value: 'n=' + (await self.vocabApi.getFilteredSampleCount(g.filter)) }, // will re-enable when filtered sample count can be supported for gdc
+      {}
+      // blank cell to show filter ui
+    ]);
+  }
+  renderTable(tableArg);
+  for (const [i, row] of tableArg.rows.entries()) {
+    row[0].__td.append("div").attr("class", "sja_menuoption").style("padding", "1px 6px").html("&times;").on("click", () => {
+      self.groups.splice(i, 1);
+      makeGroupUI(self, div);
+    });
+    const group = self.groups[i];
+    filterInit({
+      holder: row[3].__td,
+      vocabApi,
+      header_mode: "hide_search",
+      callback: (f) => {
+        if (!f || f.lst.length == 0) {
+          const i2 = self.groups.findIndex((g) => g.name == group.name);
+          self.groups.splice(i2, 1);
+        } else {
+          excludeGeneNameFromFilter(f);
+          group.filter = f;
+        }
+        makeGroupUI(self, div);
+      }
+    }).main(group.filter);
+  }
+}
+function addNewGroup(filter, groups, name) {
+  if (!groups) throw "groups is missing";
+  if (!name) {
+    const base = "New group";
+    name = base;
+    for (let i = 0; ; i++) {
+      name = base + (i === 0 ? "" : " " + i);
+      if (!groups.find((g) => g.name === name)) break;
+    }
+  }
+  excludeGeneNameFromFilter(filter);
+  const newGroup = {
+    name,
+    type: "filter",
+    filter,
+    color: rgb(colorScale(groups.length)).formatHex()
+  };
+  groups.push(newGroup);
+}
+function excludeGeneNameFromFilter(filter) {
+  for (const item of filter.lst) {
+    if (item.type == "tvslst") {
+      excludeGeneNameFromFilter(item);
+    } else if (item.type == "tvs") {
+      item.tvs.excludeGeneName = true;
+    } else {
+      throw "unexpected item.type";
+    }
+  }
+}
+function clearGroupset(self) {
+  self.q.type = "values";
+  delete self.q.predefined_groupset_idx;
+  delete self.q.customset;
+  delete self.q.dtLst;
+  delete self.q.origins;
+  delete self.q.originLabel;
+  self.q.hiddenValues = {};
+}
+export {
+  getHandler
+};
+//# sourceMappingURL=geneVariant-PWMXP6H4.js.map

package/dist/geneVariant-PWMXP6H4.js.map

@@ -0,0 +1,7 @@
+{
+  "version": 3,
+  "sources": ["../termsetting/handlers/geneVariant.ts"],
+  "sourcesContent": ["import { getPillNameDefault } from '../utils.ts'\nimport { make_radios, renderTable } from '#dom'\nimport { filterInit, filterPromptInit, getNormalRoot, excludeFilterByTag } from '#filter/filter'\nimport type { TermSetting } from '../TermSetting.ts'\nimport { vocabInit } from '#termdb/vocabulary'\nimport { getDtTermValues } from '#filter/tvs.dt'\nimport { getColors } from '#shared/common.js'\nimport { getDtsFromGroups, getTermLabelSuffix } from '#shared/terms.js'\nimport { fillGroupsetGroups } from '../../tw/geneVariant'\nimport { rgb } from 'd3-color'\n\nconst colorScale = getColors(5)\n\n// self is the termsetting instance\nexport function getHandler(self: TermSetting) {\n\treturn {\n\t\tgetPillName(d: any) {\n\t\t\tlet name = d.name\n\t\t\tif (!name) {\n\t\t\t\tif (d.genes) name = d.genes.map(g => g.gene).join(', ')\n\t\t\t\telse if (d.chr) name = `${d.chr}:${d.start}-${d.stop}`\n\t\t\t\telse name = d.id || 'geneVariant'\n\t\t\t}\n\t\t\treturn getPillNameDefault(self, { name })\n\t\t},\n\n\t\tgetPillStatus() {\n\t\t\tlet text\n\t\t\tconst q = self.q as any // TODO: migrate this handler to use client/tw code\n\t\t\tif (q.type == 'predefined-groupset') {\n\t\t\t\tconst groupsetting = self.term.groupsetting\n\t\t\t\tif (!groupsetting?.lst?.length) throw 'no predefined groupsets found'\n\t\t\t\tconst groupset = groupsetting.lst[q.predefined_groupset_idx]\n\t\t\t\ttext = groupset.name\n\t\t\t} else if (q.type == 'custom-groupset') {\n\t\t\t\tconst n = q.customset.groups.length\n\t\t\t\ttext = `Divided into ${n} groups`\n\t\t\t} else {\n\t\t\t\ttext = 'any variant class'\n\t\t\t}\n\t\t\ttext += getTermLabelSuffix(self.term, q)\n\t\t\treturn { text }\n\t\t},\n\n\t\tasync showEditMenu(div: Element) {\n\t\t\tawait makeEditMenu(self, div)\n\t\t}\n\t}\n}\n\nasync function makeEditMenu(self: TermSetting, _div: any) {\n\t/* TODO: instead of directly modifying self.q here, should create a separate property on the handler to store pending user\n\tconfigurations (similar to numeric continuous/discrete switching)\n\tconst handler = self.handlerByType.geneVariant */\n\t/* groups[] is scratch state of this menu, held only so that edits survive the re-render\n\tthat each change to it triggers, see makeGroupUI(). it must not outlive the menu: the\n\ttermsetting instance is reused across tws (see main() in TermSettingApi.ts, and the pill\n\tshared by every matrix row in matrix.interactivity.js), and nothing on a cached groups[]\n\tsays which tw it was built for. this runs once per opening of the menu, while every\n\tmakeGroupUI() call descends from it */\n\tdelete self.groups\n\tconst div = _div.append('div').style('margin', '10px')\n\tdiv.append('div').style('font-size', '1.2rem').text(self.term.name)\n\tconst optsDiv = div.append('div').style('margin-top', '10px').style('margin-bottom', '1px')\n\tconst groupsDiv = div.append('div').style('display', 'none').style('margin', '10px').style('vertical-align', 'top')\n\t// radio buttons for whether or not to group samples\n\toptsDiv.append('div').style('font-weight', 'bold').text('Group samples')\n\tconst q = self.q as any // TODO: migrate this handler to use client/tw code\n\tconst isGroupset = q.type == 'predefined-groupset' || q.type == 'custom-groupset'\n\tmake_radios({\n\t\tholder: optsDiv,\n\t\toptions: [\n\t\t\t{ label: 'No sample grouping', value: 'noGroup', checked: !isGroupset },\n\t\t\t{ label: 'Assign samples to groups', value: 'group', checked: isGroupset }\n\t\t],\n\t\tcallback: async v => {\n\t\t\tif (v == 'group') {\n\t\t\t\tif (q.type == 'values') Object.assign(q, { type: 'custom-groupset', customset: { groups: [] } })\n\t\t\t\tawait makeGroupUI(self, groupsDiv)\n\t\t\t} else {\n\t\t\t\tclearGroupset(self)\n\t\t\t\tgroupsDiv.style('display', 'none')\n\t\t\t}\n\t\t}\n\t})\n\tif (isGroupset) await makeGroupUI(self, groupsDiv)\n\n\tif (\n\t\t(self.usecase?.detail && ['term', 'term0', 'term2'].includes(self.usecase.detail)) ||\n\t\tself.opts.geneVariantEditMenuOnlyGrp\n\t) {\n\t\t// only groupsetting is allowed\n\t\t// hide option for turning off groupsetting\n\t\toptsDiv.style('display', 'none')\n\t\tgroupsDiv.style('margin', '0px')\n\t}\n\n\t// apply button\n\tdiv\n\t\t.append('div')\n\t\t.style('margin-top', '25px')\n\t\t.append('button')\n\t\t.attr('data-testid', 'sjpp-ts-gv-editui-applyBtn')\n\t\t.text('Apply')\n\t\t.on('click', () => {\n\t\t\tconst q = self.q as any // TODO: migrate this handler to use client/tw code\n\t\t\tif (q.type == 'predefined-groupset' || q.type == 'custom-groupset') {\n\t\t\t\t// groupsetting\n\t\t\t\tif (!self.groups?.length) {\n\t\t\t\t\t// no groups created\n\t\t\t\t\twindow.alert('Samples must be assigned to at least one group.')\n\t\t\t\t\treturn\n\t\t\t\t} else {\n\t\t\t\t\t// groups created, assign to custom groupset\n\t\t\t\t\tconst dtLst = getDtsFromGroups(self.groups)\n\t\t\t\t\tObject.assign(q, { type: 'custom-groupset', customset: { groups: self.groups }, dtLst })\n\t\t\t\t\t/* remember this grouping, so that a term built later for the same gene can offer\n\t\t\t\t\tit back, e.g. the BCR-ABL1 fusion grouping of a barchart overlay when the same\n\t\t\t\t\tgene is picked as the overlay of a survival plot. Only the mass store tracks\n\t\t\t\t\tthese, see rememberGvQ() in client/termdb/Vocab.js */\n\t\t\t\t\tself.vocabApi.rememberGvQ?.(self.term, q)\n\t\t\t\t}\n\t\t\t} else {\n\t\t\t\t// no groupsetting\n\t\t\t\tif (q.type != 'values') throw `q.type must be 'values'`\n\t\t\t}\n\t\t\tself.api.runCallback()\n\t\t})\n}\n\n// make UI for grouping variants\nasync function makeGroupUI(self: TermSetting, div) {\n\tdiv.style('display', 'block')\n\tdiv.selectAll('*').remove()\n\n\t// message\n\tdiv\n\t\t.append('div')\n\t\t.style('margin', '15px 0px')\n\t\t.text(\n\t\t\t'Group samples by mutation status. Samples are assigned to first possible group. Only tested samples are considered.'\n\t\t)\n\n\t// filter table\n\tconst filterTableDiv = div.append('div')\n\t// add new group button\n\tconst addNewGroupBtnHolder = div.append('div')\n\n\tconst q = self.q as any // TODO: migrate this handler to use client/tw code\n\t// get groups\n\tif (q.type != 'predefined-groupset' && q.type != 'custom-groupset') throw 'unexpected q.type'\n\t// groups[] is built once per opening of the edit menu, which cleared it, and is\n\t// then reused across the re-renders that the edits below trigger\n\tif (!self.groups) {\n\t\tlet groupset\n\t\tif (q.type == 'predefined-groupset') {\n\t\t\tconst groupsetting = self.term.groupsetting\n\t\t\tif (!groupsetting.lst?.length) throw 'no predefined groupsets found'\n\t\t\t/* a groupset only carries groups[] once it has been selected, and this UI can be\n\t\t\topened on a q whose index was not the one the term was last filled for, so build\n\t\t\ton demand rather than assume (see listPredefinedGroupsets() in tw/geneVariant.ts) */\n\t\t\tawait fillGroupsetGroups(self.term, q.predefined_groupset_idx, self.vocabApi as any, q.origins)\n\t\t\tgroupset = groupsetting.lst[q.predefined_groupset_idx]\n\t\t} else {\n\t\t\tgroupset = q.customset\n\t\t}\n\t\tif (!groupset) throw 'groupset is missing'\n\t\tif (!Array.isArray(groupset.groups)) throw 'groupset.groups is not array'\n\t\tself.groups = structuredClone(groupset.groups)\n\t}\n\n\t// fill values of child dt terms with mutation classes of gene in dataset.\n\t// filled into copies rather than self.term.childTerms[], because each of those\n\t// is shared by reference with the tvs of every groupset, and the mname tally\n\t// requested here would then be serialized once per tvs into the saved term\n\tconst dtTerms = structuredClone(self.term.childTerms)\n\tfor (const dtTerm of dtTerms) {\n\t\tawait getDtTermValues(dtTerm, self.filter, self.vocabApi, { withMnames: true })\n\t}\n\n\t// build frontend vocab using child dt terms. it is the only source of values and\n\t// mnames for the tvs of this UI, since a frontend vocab cannot query the db\n\t// (see getDtTermValues() in filter/tvs.dt.js)\n\tconst vocabApi: any = vocabInit({ vocab: { terms: dtTerms } })\n\t// need termdbConfig.queries for cnv tvs (see getDtCnvType() in filter/tvs.js and\n\t// fillMenu() in filter/tvs.dtcnv.continuous.js), and .assayAvailability so that a tvs\n\t// over an origin-split dt offers its origin selector here (see getTvsByOrigin() in\n\t// filter/tvs.dt.js) -- this menu is where mutation types of differing origins are\n\t// combined, so it is the one place that selector matters most\n\t// not passing complete termdbConfig as presence of .allowedTermTypes will\n\t// trigger term type toggles (see init() in termdb/TermTypeSearch.ts)\n\tvocabApi.termdbConfig = {\n\t\tqueries: self.vocabApi.termdbConfig.queries,\n\t\tassayAvailability: self.vocabApi.termdbConfig.assayAvailability\n\t}\n\t// genome is needed to look up the isoform models of a gene, to chart the breakpoints\n\t// of a sv/fusion over (see fillMenu() in filter/tvs.dt.js)\n\tvocabApi.vocab.genome = self.vocabApi.vocab?.genome\n\n\t// filter prompt\n\tconst filterPrompt = await filterPromptInit({\n\t\tholder: addNewGroupBtnHolder,\n\t\tvocabApi,\n\t\temptyLabel: 'Add group',\n\t\theader_mode: 'hide_search',\n\t\tcallback: f => {\n\t\t\tconst filter = getNormalRoot(f)\n\t\t\taddNewGroup(filter, self.groups)\n\t\t\tmakeGroupUI(self, div)\n\t\t},\n\t\tdebug: self.opts.debug\n\t})\n\n\t// filterPrompt.main() always empties the filterUiRoot data\n\tconst filter = structuredClone(self.filter)\n\tfilterPrompt.main(excludeFilterByTag(filter, 'cohortFilter')) // provide mass filter to limit the term tree\n\n\tif (!self.groups.length) {\n\t\t// no groups, hide table\n\t\tfilterTableDiv.style('display', 'none')\n\t\treturn\n\t}\n\n\t// clear table and populate rows\n\tfilterTableDiv.style('display', '').selectAll('*').remove()\n\tconst tableArg: any = {\n\t\tdiv: filterTableDiv,\n\t\tcolumns: [\n\t\t\t{}, // blank column to add delete buttons\n\t\t\t{\n\t\t\t\tlabel: 'NAME',\n\t\t\t\teditCallback: async (i, cell) => {\n\t\t\t\t\tconst newName = cell.value\n\t\t\t\t\tconst index = self.groups.findIndex(group => group.name == newName)\n\t\t\t\t\tif (index != -1) {\n\t\t\t\t\t\talert(`Group named ${newName} already exists`)\n\t\t\t\t\t\tmakeGroupUI(self, div)\n\t\t\t\t\t} else {\n\t\t\t\t\t\tself.groups[i].name = newName\n\t\t\t\t\t\tmakeGroupUI(self, div)\n\t\t\t\t\t}\n\t\t\t\t}\n\t\t\t},\n\t\t\t{\n\t\t\t\tlabel: 'COLOR',\n\t\t\t\teditCallback: async (i, cell) => {\n\t\t\t\t\tself.groups[i].color = cell.color\n\t\t\t\t\tmakeGroupUI(self, div)\n\t\t\t\t}\n\t\t\t},\n\t\t\t//{ label: '#SAMPLE' }, // will re-enable when filtered sample count can be supported for gdc\n\t\t\t{ label: 'FILTER' }\n\t\t],\n\t\trows: [],\n\t\tstriped: false, // no alternating row bg color so delete button appears more visible\n\t\tshowLines: false\n\t}\n\n\tfor (const g of self.groups) {\n\t\ttableArg.rows.push([\n\t\t\t{}, // blank cell to add delete button\n\t\t\t{ value: g.name }, // to allow click to show <input>\n\t\t\t{ color: g.color },\n\t\t\t// { value: 'n=' + (await self.vocabApi.getFilteredSampleCount(g.filter)) }, // will re-enable when filtered sample count can be supported for gdc\n\t\t\t{} // blank cell to show filter ui\n\t\t])\n\t}\n\n\trenderTable(tableArg)\n\n\t// after rendering table, iterate over rows again to fill cells with control elements\n\tfor (const [i, row] of tableArg.rows.entries()) {\n\t\t// add delete button in 1st cell\n\t\trow[0].__td\n\t\t\t.append('div')\n\t\t\t.attr('class', 'sja_menuoption')\n\t\t\t.style('padding', '1px 6px')\n\t\t\t.html('&times;')\n\t\t\t.on('click', () => {\n\t\t\t\tself.groups.splice(i, 1)\n\t\t\t\tmakeGroupUI(self, div)\n\t\t\t})\n\n\t\t// create filter ui in its cell\n\t\tconst group = self.groups[i]\n\t\tfilterInit({\n\t\t\tholder: row[3].__td,\n\t\t\tvocabApi,\n\t\t\theader_mode: 'hide_search',\n\t\t\tcallback: f => {\n\t\t\t\tif (!f || f.lst.length == 0) {\n\t\t\t\t\t// blank filter (user removed last tvs from this filter), delete this element from groups[]\n\t\t\t\t\tconst i = self.groups.findIndex(g => g.name == group.name)\n\t\t\t\t\tself.groups.splice(i, 1)\n\t\t\t\t} else {\n\t\t\t\t\t// update filter\n\t\t\t\t\texcludeGeneNameFromFilter(f) // no need to show gene name in filter pill\n\t\t\t\t\tgroup.filter = f\n\t\t\t\t}\n\t\t\t\tmakeGroupUI(self, div)\n\t\t\t}\n\t\t}).main(group.filter)\n\t}\n}\n\nfunction addNewGroup(filter, groups, name?: string) {\n\tif (!groups) throw 'groups is missing'\n\tif (!name) {\n\t\tconst base = 'New group'\n\t\tname = base\n\t\tfor (let i = 0; ; i++) {\n\t\t\tname = base + (i === 0 ? '' : ' ' + i)\n\t\t\tif (!groups.find(g => g.name === name)) break\n\t\t}\n\t}\n\texcludeGeneNameFromFilter(filter) // no need to show gene name in filter pill\n\tconst newGroup = {\n\t\tname,\n\t\ttype: 'filter',\n\t\tfilter,\n\t\tcolor: rgb(colorScale(groups.length)).formatHex()\n\t}\n\tgroups.push(newGroup)\n}\n\nfunction excludeGeneNameFromFilter(filter) {\n\tfor (const item of filter.lst) {\n\t\tif (item.type == 'tvslst') {\n\t\t\texcludeGeneNameFromFilter(item)\n\t\t} else if (item.type == 'tvs') {\n\t\t\titem.tvs.excludeGeneName = true\n\t\t} else {\n\t\t\tthrow 'unexpected item.type'\n\t\t}\n\t}\n}\n\nfunction clearGroupset(self) {\n\tself.q.type = 'values'\n\tdelete self.q.predefined_groupset_idx\n\tdelete self.q.customset\n\t// dtLst limits the dts queried for the term and is only meaningful for a\n\t// groupset; leaving it behind would silently restrict an ungrouped term to\n\t// the dts of the groupset that was just cleared (see getDtsToQuery() in\n\t// server/src/mds3.init.js)\n\tdelete self.q.dtLst\n\t// the seed a predefined groupset stamps onto its tvs (see OriginSeedQ in #types). an\n\t// ungrouped term has no tvs and queries every origin, so a seed left behind is dead\n\t// state that would come back into effect when a groupset is selected again\n\tdelete self.q.origins\n\tdelete self.q.originLabel\n\t// hiddenValues of a groupset are keyed by group name, which is meaningless\n\t// once the term is back to mutation classes. reset rather than delete, as\n\t// consumers may read it without a guard\n\tself.q.hiddenValues = {}\n}\n"],
+  "mappings": ";;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;AAWA,IAAM,aAAa,UAAU,CAAC;AAGvB,SAAS,WAAW,MAAmB;AAC7C,SAAO;AAAA,IACN,YAAY,GAAQ;AACnB,UAAI,OAAO,EAAE;AACb,UAAI,CAAC,MAAM;AACV,YAAI,EAAE,MAAO,QAAO,EAAE,MAAM,IAAI,OAAK,EAAE,IAAI,EAAE,KAAK,IAAI;AAAA,iBAC7C,EAAE,IAAK,QAAO,GAAG,EAAE,GAAG,IAAI,EAAE,KAAK,IAAI,EAAE,IAAI;AAAA,YAC/C,QAAO,EAAE,MAAM;AAAA,MACrB;AACA,aAAO,mBAAmB,MAAM,EAAE,KAAK,CAAC;AAAA,IACzC;AAAA,IAEA,gBAAgB;AACf,UAAI;AACJ,YAAM,IAAI,KAAK;AACf,UAAI,EAAE,QAAQ,uBAAuB;AACpC,cAAM,eAAe,KAAK,KAAK;AAC/B,YAAI,CAAC,cAAc,KAAK,OAAQ,OAAM;AACtC,cAAM,WAAW,aAAa,IAAI,EAAE,uBAAuB;AAC3D,eAAO,SAAS;AAAA,MACjB,WAAW,EAAE,QAAQ,mBAAmB;AACvC,cAAM,IAAI,EAAE,UAAU,OAAO;AAC7B,eAAO,gBAAgB,CAAC;AAAA,MACzB,OAAO;AACN,eAAO;AAAA,MACR;AACA,cAAQ,mBAAmB,KAAK,MAAM,CAAC;AACvC,aAAO,EAAE,KAAK;AAAA,IACf;AAAA,IAEA,MAAM,aAAa,KAAc;AAChC,YAAM,aAAa,MAAM,GAAG;AAAA,IAC7B;AAAA,EACD;AACD;AAEA,eAAe,aAAa,MAAmB,MAAW;AAUzD,SAAO,KAAK;AACZ,QAAM,MAAM,KAAK,OAAO,KAAK,EAAE,MAAM,UAAU,MAAM;AACrD,MAAI,OAAO,KAAK,EAAE,MAAM,aAAa,QAAQ,EAAE,KAAK,KAAK,KAAK,IAAI;AAClE,QAAM,UAAU,IAAI,OAAO,KAAK,EAAE,MAAM,cAAc,MAAM,EAAE,MAAM,iBAAiB,KAAK;AAC1F,QAAM,YAAY,IAAI,OAAO,KAAK,EAAE,MAAM,WAAW,MAAM,EAAE,MAAM,UAAU,MAAM,EAAE,MAAM,kBAAkB,KAAK;AAElH,UAAQ,OAAO,KAAK,EAAE,MAAM,eAAe,MAAM,EAAE,KAAK,eAAe;AACvE,QAAM,IAAI,KAAK;AACf,QAAM,aAAa,EAAE,QAAQ,yBAAyB,EAAE,QAAQ;AAChE,cAAY;AAAA,IACX,QAAQ;AAAA,IACR,SAAS;AAAA,MACR,EAAE,OAAO,sBAAsB,OAAO,WAAW,SAAS,CAAC,WAAW;AAAA,MACtE,EAAE,OAAO,4BAA4B,OAAO,SAAS,SAAS,WAAW;AAAA,IAC1E;AAAA,IACA,UAAU,OAAM,MAAK;AACpB,UAAI,KAAK,SAAS;AACjB,YAAI,EAAE,QAAQ,SAAU,QAAO,OAAO,GAAG,EAAE,MAAM,mBAAmB,WAAW,EAAE,QAAQ,CAAC,EAAE,EAAE,CAAC;AAC/F,cAAM,YAAY,MAAM,SAAS;AAAA,MAClC,OAAO;AACN,sBAAc,IAAI;AAClB,kBAAU,MAAM,WAAW,MAAM;AAAA,MAClC;AAAA,IACD;AAAA,EACD,CAAC;AACD,MAAI,WAAY,OAAM,YAAY,MAAM,SAAS;AAEjD,MACE,KAAK,SAAS,UAAU,CAAC,QAAQ,SAAS,OAAO,EAAE,SAAS,KAAK,QAAQ,MAAM,KAChF,KAAK,KAAK,4BACT;AAGD,YAAQ,MAAM,WAAW,MAAM;AAC/B,cAAU,MAAM,UAAU,KAAK;AAAA,EAChC;AAGA,MACE,OAAO,KAAK,EACZ,MAAM,cAAc,MAAM,EAC1B,OAAO,QAAQ,EACf,KAAK,eAAe,4BAA4B,EAChD,KAAK,OAAO,EACZ,GAAG,SAAS,MAAM;AAClB,UAAMA,KAAI,KAAK;AACf,QAAIA,GAAE,QAAQ,yBAAyBA,GAAE,QAAQ,mBAAmB;AAEnE,UAAI,CAAC,KAAK,QAAQ,QAAQ;AAEzB,eAAO,MAAM,iDAAiD;AAC9D;AAAA,MACD,OAAO;AAEN,cAAM,QAAQ,iBAAiB,KAAK,MAAM;AAC1C,eAAO,OAAOA,IAAG,EAAE,MAAM,mBAAmB,WAAW,EAAE,QAAQ,KAAK,OAAO,GAAG,MAAM,CAAC;AAKvF,aAAK,SAAS,cAAc,KAAK,MAAMA,EAAC;AAAA,MACzC;AAAA,IACD,OAAO;AAEN,UAAIA,GAAE,QAAQ,SAAU,OAAM;AAAA,IAC/B;AACA,SAAK,IAAI,YAAY;AAAA,EACtB,CAAC;AACH;AAGA,eAAe,YAAY,MAAmB,KAAK;AAClD,MAAI,MAAM,WAAW,OAAO;AAC5B,MAAI,UAAU,GAAG,EAAE,OAAO;AAG1B,MACE,OAAO,KAAK,EACZ,MAAM,UAAU,UAAU,EAC1B;AAAA,IACA;AAAA,EACD;AAGD,QAAM,iBAAiB,IAAI,OAAO,KAAK;AAEvC,QAAM,uBAAuB,IAAI,OAAO,KAAK;AAE7C,QAAM,IAAI,KAAK;AAEf,MAAI,EAAE,QAAQ,yBAAyB,EAAE,QAAQ,kBAAmB,OAAM;AAG1E,MAAI,CAAC,KAAK,QAAQ;AACjB,QAAI;AACJ,QAAI,EAAE,QAAQ,uBAAuB;AACpC,YAAM,eAAe,KAAK,KAAK;AAC/B,UAAI,CAAC,aAAa,KAAK,OAAQ,OAAM;AAIrC,YAAM,mBAAmB,KAAK,MAAM,EAAE,yBAAyB,KAAK,UAAiB,EAAE,OAAO;AAC9F,iBAAW,aAAa,IAAI,EAAE,uBAAuB;AAAA,IACtD,OAAO;AACN,iBAAW,EAAE;AAAA,IACd;AACA,QAAI,CAAC,SAAU,OAAM;AACrB,QAAI,CAAC,MAAM,QAAQ,SAAS,MAAM,EAAG,OAAM;AAC3C,SAAK,SAAS,gBAAgB,SAAS,MAAM;AAAA,EAC9C;AAMA,QAAM,UAAU,gBAAgB,KAAK,KAAK,UAAU;AACpD,aAAW,UAAU,SAAS;AAC7B,UAAM,gBAAgB,QAAQ,KAAK,QAAQ,KAAK,UAAU,EAAE,YAAY,KAAK,CAAC;AAAA,EAC/E;AAKA,QAAM,WAAgB,UAAU,EAAE,OAAO,EAAE,OAAO,QAAQ,EAAE,CAAC;AAQ7D,WAAS,eAAe;AAAA,IACvB,SAAS,KAAK,SAAS,aAAa;AAAA,IACpC,mBAAmB,KAAK,SAAS,aAAa;AAAA,EAC/C;AAGA,WAAS,MAAM,SAAS,KAAK,SAAS,OAAO;AAG7C,QAAM,eAAe,MAAM,iBAAiB;AAAA,IAC3C,QAAQ;AAAA,IACR;AAAA,IACA,YAAY;AAAA,IACZ,aAAa;AAAA,IACb,UAAU,OAAK;AACd,YAAMC,UAAS,cAAc,CAAC;AAC9B,kBAAYA,SAAQ,KAAK,MAAM;AAC/B,kBAAY,MAAM,GAAG;AAAA,IACtB;AAAA,IACA,OAAO,KAAK,KAAK;AAAA,EAClB,CAAC;AAGD,QAAM,SAAS,gBAAgB,KAAK,MAAM;AAC1C,eAAa,KAAK,mBAAmB,QAAQ,cAAc,CAAC;AAE5D,MAAI,CAAC,KAAK,OAAO,QAAQ;AAExB,mBAAe,MAAM,WAAW,MAAM;AACtC;AAAA,EACD;AAGA,iBAAe,MAAM,WAAW,EAAE,EAAE,UAAU,GAAG,EAAE,OAAO;AAC1D,QAAM,WAAgB;AAAA,IACrB,KAAK;AAAA,IACL,SAAS;AAAA,MACR,CAAC;AAAA;AAAA,MACD;AAAA,QACC,OAAO;AAAA,QACP,cAAc,OAAO,GAAG,SAAS;AAChC,gBAAM,UAAU,KAAK;AACrB,gBAAM,QAAQ,KAAK,OAAO,UAAU,WAAS,MAAM,QAAQ,OAAO;AAClE,cAAI,SAAS,IAAI;AAChB,kBAAM,eAAe,OAAO,iBAAiB;AAC7C,wBAAY,MAAM,GAAG;AAAA,UACtB,OAAO;AACN,iBAAK,OAAO,CAAC,EAAE,OAAO;AACtB,wBAAY,MAAM,GAAG;AAAA,UACtB;AAAA,QACD;AAAA,MACD;AAAA,MACA;AAAA,QACC,OAAO;AAAA,QACP,cAAc,OAAO,GAAG,SAAS;AAChC,eAAK,OAAO,CAAC,EAAE,QAAQ,KAAK;AAC5B,sBAAY,MAAM,GAAG;AAAA,QACtB;AAAA,MACD;AAAA;AAAA,MAEA,EAAE,OAAO,SAAS;AAAA,IACnB;AAAA,IACA,MAAM,CAAC;AAAA,IACP,SAAS;AAAA;AAAA,IACT,WAAW;AAAA,EACZ;AAEA,aAAW,KAAK,KAAK,QAAQ;AAC5B,aAAS,KAAK,KAAK;AAAA,MAClB,CAAC;AAAA;AAAA,MACD,EAAE,OAAO,EAAE,KAAK;AAAA;AAAA,MAChB,EAAE,OAAO,EAAE,MAAM;AAAA;AAAA,MAEjB,CAAC;AAAA;AAAA,IACF,CAAC;AAAA,EACF;AAEA,cAAY,QAAQ;AAGpB,aAAW,CAAC,GAAG,GAAG,KAAK,SAAS,KAAK,QAAQ,GAAG;AAE/C,QAAI,CAAC,EAAE,KACL,OAAO,KAAK,EACZ,KAAK,SAAS,gBAAgB,EAC9B,MAAM,WAAW,SAAS,EAC1B,KAAK,SAAS,EACd,GAAG,SAAS,MAAM;AAClB,WAAK,OAAO,OAAO,GAAG,CAAC;AACvB,kBAAY,MAAM,GAAG;AAAA,IACtB,CAAC;AAGF,UAAM,QAAQ,KAAK,OAAO,CAAC;AAC3B,eAAW;AAAA,MACV,QAAQ,IAAI,CAAC,EAAE;AAAA,MACf;AAAA,MACA,aAAa;AAAA,MACb,UAAU,OAAK;AACd,YAAI,CAAC,KAAK,EAAE,IAAI,UAAU,GAAG;AAE5B,gBAAMC,KAAI,KAAK,OAAO,UAAU,OAAK,EAAE,QAAQ,MAAM,IAAI;AACzD,eAAK,OAAO,OAAOA,IAAG,CAAC;AAAA,QACxB,OAAO;AAEN,oCAA0B,CAAC;AAC3B,gBAAM,SAAS;AAAA,QAChB;AACA,oBAAY,MAAM,GAAG;AAAA,MACtB;AAAA,IACD,CAAC,EAAE,KAAK,MAAM,MAAM;AAAA,EACrB;AACD;AAEA,SAAS,YAAY,QAAQ,QAAQ,MAAe;AACnD,MAAI,CAAC,OAAQ,OAAM;AACnB,MAAI,CAAC,MAAM;AACV,UAAM,OAAO;AACb,WAAO;AACP,aAAS,IAAI,KAAK,KAAK;AACtB,aAAO,QAAQ,MAAM,IAAI,KAAK,MAAM;AACpC,UAAI,CAAC,OAAO,KAAK,OAAK,EAAE,SAAS,IAAI,EAAG;AAAA,IACzC;AAAA,EACD;AACA,4BAA0B,MAAM;AAChC,QAAM,WAAW;AAAA,IAChB;AAAA,IACA,MAAM;AAAA,IACN;AAAA,IACA,OAAO,IAAI,WAAW,OAAO,MAAM,CAAC,EAAE,UAAU;AAAA,EACjD;AACA,SAAO,KAAK,QAAQ;AACrB;AAEA,SAAS,0BAA0B,QAAQ;AAC1C,aAAW,QAAQ,OAAO,KAAK;AAC9B,QAAI,KAAK,QAAQ,UAAU;AAC1B,gCAA0B,IAAI;AAAA,IAC/B,WAAW,KAAK,QAAQ,OAAO;AAC9B,WAAK,IAAI,kBAAkB;AAAA,IAC5B,OAAO;AACN,YAAM;AAAA,IACP;AAAA,EACD;AACD;AAEA,SAAS,cAAc,MAAM;AAC5B,OAAK,EAAE,OAAO;AACd,SAAO,KAAK,EAAE;AACd,SAAO,KAAK,EAAE;AAKd,SAAO,KAAK,EAAE;AAId,SAAO,KAAK,EAAE;AACd,SAAO,KAAK,EAAE;AAId,OAAK,EAAE,eAAe,CAAC;AACxB;",
+  "names": ["q", "filter", "i"]
+}