@sjcrh/proteinpaint-client 2.223.0 → 2.224.0
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/2dmaf-AHG6N6GX.js +1362 -0
- package/dist/AggMatrixInput-A4EATVXG.js +402 -0
- package/dist/AggregateMatrix-3D36XP7Q.js +37 -0
- package/dist/AppHeader-LBFNK6BI.js +826 -0
- package/dist/BoxPlot-JNISSUMV.js +1229 -0
- package/dist/CorrelationVolcano-BXXFXVHQ.js +613 -0
- package/dist/Cuminc-PYG3TJSE.js +1217 -0
- package/dist/DE-QGNB5JKB.js +85 -0
- package/dist/DEinput-YVXCVTCX.js +479 -0
- package/dist/DM-D37YHRJL.js +86 -0
- package/dist/DifferentialAnalysis-TFWK7UE7.js +236 -0
- package/dist/Disco-PXBROYMP.js +3384 -0
- package/dist/Disco.UI-XERJSEDE.js +239 -0
- package/dist/DmrPlot-G3QAPQ5I.js +361 -0
- package/dist/GB-BLGXVCL2.js +1388 -0
- package/dist/GSEA-ZQNLH62K.js +870 -0
- package/dist/GeneExpInput-EYNET6LR.js +38 -0
- package/dist/Geomap-OTF5DRZT.js +80 -0
- package/dist/HicApp-APZFHM2A.js +2240 -0
- package/dist/IDCViewer-Q5PM7G5F.js +10808 -0
- package/dist/NumBinaryEditor-DSQDMP4L.js +274 -0
- package/dist/NumBinaryEditor.unit.spec-DXKUI7ZJ.js +308 -0
- package/dist/NumContEditor-7EYKJTAM.js +100 -0
- package/dist/NumContEditor.unit.spec-3TGAJSIH.js +160 -0
- package/dist/NumCustomBinEditor-7YK4DHNY.js +29 -0
- package/dist/NumCustomBinEditor.unit.spec-UG4QP4SJ.js +393 -0
- package/dist/NumDiscreteEditor-J2U7HNKJ.js +165 -0
- package/dist/NumDiscreteEditor.unit.spec-4GJMCLZB.js +229 -0
- package/dist/NumRegularBinEditor-R7KDRY3C.js +29 -0
- package/dist/NumRegularBinEditor.unit.spec-7QORM76Z.js +274 -0
- package/dist/NumSplineEditor-TY7QSYBC.js +205 -0
- package/dist/NumSplineEditor.unit.spec-NRP4XDUK.js +220 -0
- package/dist/NumericDensity-X3WDJHHT.js +29 -0
- package/dist/NumericDensity.unit.spec-LPW5M4MB.js +414 -0
- package/dist/NumericHandler-E7H7WJHR.js +30 -0
- package/dist/NumericHandler.unit.spec-FE2LOGCS.js +225 -0
- package/dist/ProteomeInput-4M2SXSJG.js +610 -0
- package/dist/Regression-GXAACUGA.js +1412 -0
- package/dist/RunChart2-ZE7RGJEJ.js +744 -0
- package/dist/SC-4O73EKKZ.js +1290 -0
- package/dist/Violin-AR74D2S5.js +1092 -0
- package/dist/Volcano-NC6CM3FY.js +2657 -0
- package/dist/Volcano-NC6CM3FY.js.map +7 -0
- package/dist/Wsi-AR2WRIQO.js +636 -0
- package/dist/aboutSunburst-3KM2UULF.js +93 -0
- package/dist/adSandbox-WJ4KBWMU.js +29 -0
- package/dist/animatedBubbleChart-ASVK3MS5.js +542 -0
- package/dist/app-V2TCAQ4U.js +28 -0
- package/dist/app-X4AN7T54.js +38 -0
- package/dist/app.js +10 -10
- package/dist/bam-5PYKCF2J.js +872 -0
- package/dist/barchart-CM3XHZTA.js +38 -0
- package/dist/barchart2-SC63JKN5.js +305 -0
- package/dist/block-LYSTIZKO.js +6203 -0
- package/dist/block.init-PCK3GPSX.js +29 -0
- package/dist/block.mds.expressionrank-C66QPAGB.js +350 -0
- package/dist/block.mds.geneboxplot-MNER4EZ5.js +819 -0
- package/dist/block.mds.junction-2R4UBHO7.js +1534 -0
- package/dist/block.mds.svcnv-FHGLK36W.js +6325 -0
- package/dist/block.svg-CNO5DO4Y.js +155 -0
- package/dist/block.tk.aicheck-6A3JDKF2.js +274 -0
- package/dist/block.tk.bam-RBTLQF4P.js +1906 -0
- package/dist/block.tk.bigwig.ui-E7KNTBTB.js +202 -0
- package/dist/block.tk.hicstraw-C6FTURLI.js +814 -0
- package/dist/block.tk.junction-B4ZMCASB.js +2353 -0
- package/dist/block.tk.junction.textmatrixui-OAQVVD7S.js +190 -0
- package/dist/block.tk.ld-QFZA5KX3.js +90 -0
- package/dist/block.tk.menu-XORKRT37.js +1050 -0
- package/dist/block.tk.pgv-WI7IV5X2.js +934 -0
- package/dist/brainImaging-WNEQQ3RS.js +550 -0
- package/dist/brainRegions-WKCAU4NE.js +213 -0
- package/dist/bubbleHeatmap-CYHNKNYP.js +374 -0
- package/dist/cellTypeBubbleHeatmap-N6JWAUWC.js +274 -0
- package/dist/chunk-2GWAEK4R.js +276 -0
- package/dist/chunk-2Q3ETPV2.js +296 -0
- package/dist/chunk-3FRAKLFY.js +2102 -0
- package/dist/chunk-4XFL2PXO.js +257 -0
- package/dist/chunk-5MBKRZWI.js +96 -0
- package/dist/chunk-5NQXKUJ3.js +243 -0
- package/dist/chunk-5WZ3ZWZC.js +6375 -0
- package/dist/chunk-64RXHMGN.js +2922 -0
- package/dist/chunk-64RXHMGN.js.map +7 -0
- package/dist/chunk-6PBTY7CY.js +255 -0
- package/dist/chunk-7T42GBVS.js +379 -0
- package/dist/chunk-7WGPCIRT.js +2685 -0
- package/dist/chunk-CCCJPKPR.js +652 -0
- package/dist/chunk-CIF2HSFF.js +848 -0
- package/dist/chunk-CLCHYFFY.js +82 -0
- package/dist/chunk-CMLHNNB2.js +1339 -0
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- package/dist/chunk-GSKQNIHP.js +626 -0
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- package/dist/chunk-LOCZDGJO.js +480 -0
- package/dist/chunk-LP54W3BC.js +56 -0
- package/dist/chunk-M7L34WTV.js +240 -0
- package/dist/chunk-MPYLBO7E.js +54 -0
- package/dist/chunk-MVZWVLLA.js +1253 -0
- package/dist/chunk-N3XBGDFY.js +159 -0
- package/dist/chunk-NYJR4ELG.js +4389 -0
- package/dist/chunk-O3XTTT4K.js +217 -0
- package/dist/chunk-OJH2LKPN.js +299 -0
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- package/dist/chunk-RQPXQOAX.js +692 -0
- package/dist/chunk-RXJTJDPZ.js +54 -0
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- package/dist/chunk-SAYYZU35.js +5214 -0
- package/dist/chunk-SMVZ6AN5.js +123 -0
- package/dist/chunk-T3VFO5NA.js +550 -0
- package/dist/chunk-U45YALDI.js +26716 -0
- package/dist/chunk-U45YALDI.js.map +7 -0
- package/dist/chunk-UP2ZRNZD.js +340 -0
- package/dist/chunk-VBRCIPFK.js +182 -0
- package/dist/chunk-VDXHBYZS.js +35 -0
- package/dist/chunk-VFLGHCUO.js +194 -0
- package/dist/chunk-VJALVBYH.js +102 -0
- package/dist/chunk-W3DJIU4H.js +102 -0
- package/dist/chunk-W46Q37IZ.js +141 -0
- package/dist/chunk-WHF2BXCF.js +56 -0
- package/dist/chunk-XAA5QWS3.js +466 -0
- package/dist/chunk-XF67G5YB.js +237 -0
- package/dist/chunk-XPQV3UZJ.js +176 -0
- package/dist/chunk-Y3GKZVCQ.js +468 -0
- package/dist/cohort-XASFFGZP.js +66 -0
- package/dist/cohortSunburst-HEXOA7M4.js +402 -0
- package/dist/condition-ZDF5SRLZ.js +323 -0
- package/dist/controls-Z4URI2HB.js +30 -0
- package/dist/controls.config-353QCQTZ.js +30 -0
- package/dist/correlation-4LIZRR2U.js +91 -0
- package/dist/customdata.inputui-AECESQA6.js +280 -0
- package/dist/dataDownload-LJPBW5RL.js +326 -0
- package/dist/databrowser.ui-IJ75U47I.js +421 -0
- package/dist/dictionary-S4MSWVZV.js +109 -0
- package/dist/dnaMethylation-QMKO3DXK.js +29 -0
- package/dist/dnaMethylation.integration.spec-XGMDB2IK.js +194 -0
- package/dist/dofetch-4P5F5ZGU.js +49 -0
- package/dist/e2pca-TS6JJLVI.js +340 -0
- package/dist/ep-S76L4MUE.js +1247 -0
- package/dist/expclust.gdc.spec-S75GMZYG.js +298 -0
- package/dist/facet-YFLHDE77.js +556 -0
- package/dist/gb-KP2WZN6P.js +77 -0
- package/dist/geneExpClustering-QTUBMZ6X.js +240 -0
- package/dist/geneExpression-6JNMJMWW.js +309 -0
- package/dist/geneExpression-JVVUKN4A.js +29 -0
- package/dist/geneExpression.unit.spec-2SANMIWR.js +151 -0
- package/dist/geneORA-NWJCROO7.js +269 -0
- package/dist/geneRanking-K6E7MT33.js +544 -0
- package/dist/geneVariant-3KV4PCMU.js +289 -0
- package/dist/geneVariant-FICL4MXY.js +32 -0
- package/dist/geneVariant.integration.spec-ANHTHANE.js +672 -0
- package/dist/genefusion.ui-3RYS5UPO.js +299 -0
- package/dist/geneset-UODQ45RY.js +199 -0
- package/dist/genomeBrowser.spec-6YCQISMJ.js +272 -0
- package/dist/grin2-WN32DXUL.js +945 -0
- package/dist/grin2-ZLU7NL6L.js +66 -0
- package/dist/hierCluster-36UVKTYM.js +51 -0
- package/dist/hierCluster-W5GMLGYX.js +55 -0
- package/dist/hierCluster.config-R5TSOJXJ.js +32 -0
- package/dist/hierCluster.integration.spec-DWKVGISB.js +479 -0
- package/dist/hierCluster.interactivity-5EFMAIWI.js +45 -0
- package/dist/imagePlot-BJAQGEBF.js +152 -0
- package/dist/importPlot-CEK76RBM.js +8 -0
- package/dist/isoformExpression-QOJ5RAB6.js +31 -0
- package/dist/isoformExpression.unit.spec-73Z5IT2B.js +233 -0
- package/dist/junction-6GSHMBTA.js +32 -0
- package/dist/junction.unit.spec-N45VJHZC.js +178 -0
- package/dist/launch.adhoc-QTDSBMG2.js +33 -0
- package/dist/leftlabel.sample-4ZY2RAXT.js +253 -0
- package/dist/lollipop-TNBUY55O.js +162 -0
- package/dist/maf-O5DQLUM6.js +451 -0
- package/dist/maftimeline-77RLW7FI.js +583 -0
- package/dist/matrix-KWYUKXMK.js +55 -0
- package/dist/matrix-TFFEEDIA.js +50 -0
- package/dist/matrix.config-RO3SVOXR.js +33 -0
- package/dist/matrix.integration.spec-SVRHEE3X.js +3156 -0
- package/dist/matrix.interactivity-IFAZAA5Z.js +33 -0
- package/dist/matrix.layout-YBOMANSO.js +35 -0
- package/dist/matrix.renderers-GMFIA6FN.js +30 -0
- package/dist/matrix.sort.unit.spec-OTC5SKDW.js +464 -0
- package/dist/matrix.sorterUi.unit.spec-2AJSZUK3.js +334 -0
- package/dist/matrix.unit.spec-BHFL7H6D.js +146 -0
- package/dist/mavb-6SHMALCY.js +726 -0
- package/dist/mds.samplescatterplot-3JODEENU.js +1545 -0
- package/dist/mds.survivalplot-ULRIJGIS.js +472 -0
- package/dist/multivalue-G2AILJHU.js +79 -0
- package/dist/oncomatrix-X5BFAMYH.js +286 -0
- package/dist/oncomatrix.spec-MLIE6VVA.js +439 -0
- package/dist/plot.2dvaf-FG3LJGP5.js +368 -0
- package/dist/plot.app-VLWWYTVJ.js +32 -0
- package/dist/plot.barplot-CXO6EEMZ.js +93 -0
- package/dist/plot.boxplot-FOXP2N7H.js +142 -0
- package/dist/plot.brainImaging-Y36M3BBW.js +51 -0
- package/dist/plot.disco-YY3ITSSS.js +98 -0
- package/dist/plot.ssgq-3UGJTTCN.js +130 -0
- package/dist/plot.vaf2cov-4FD5IA7A.js +249 -0
- package/dist/polar2-VK4MADEW.js +228 -0
- package/dist/profileForms-53MNCKET.js +937 -0
- package/dist/profilePlot-SPLM6VD4.js +45 -0
- package/dist/proteinView-ZHNMVSLF.js +1346 -0
- package/dist/proteomeCohortCompare-WGUPOLE3.js +866 -0
- package/dist/pseudbulk.unit.spec-Y4CRM6VQ.js +82 -0
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- package/dist/render-O244ZE5A.js +29 -0
- package/dist/report-47ASX5AT.js +213 -0
- package/dist/sampleView-SS5PCWRL.js +39 -0
- package/dist/samplelst-CZV77Z7N.js +114 -0
- package/dist/samplematrix-TXGERKS2.js +2188 -0
- package/dist/sc-XN44V5EK.js +77 -0
- package/dist/scatter-4B7LPX6B.js +84 -0
- package/dist/scatter-DXGINZED.js +919 -0
- package/dist/selectGenomeWithTklst-YQMYWVXF.js +125 -0
- package/dist/singleCellCellType-AJEAQL4Y.js +29 -0
- package/dist/singleCellCellType.unit.spec-7YCO4VV7.js +150 -0
- package/dist/singleCellGeneExpression-LPDACSPJ.js +29 -0
- package/dist/singleCellGeneExpression.unit.spec-JZHG5OAH.js +144 -0
- package/dist/singleCellNumericValue-SDUSPCBR.js +29 -0
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- package/dist/singleCellPlot-5AAE5QGD.js +44 -0
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- package/dist/studyCatalog-TOGQ24WQ.js +457 -0
- package/dist/summarizeCnvGeneexp-6Z3VVSMQ.js +154 -0
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- package/dist/summarizeMutationDiagnosis-PVOTM3DF.js +31 -0
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- package/dist/summary-RNNIEEHQ.js +40 -0
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- package/dist/sunburst-MYKDYBVD.js +34 -0
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- /package/dist/{tk-UHDGIDTK.js.map → tk-7OE7QMYG.js.map} +0 -0
- /package/dist/{tk-JBLKYKKI.js.map → tk-R6IBTAYE.js.map} +0 -0
- /package/dist/{tp.ui-X2BJWXKN.js.map → tp.ui-BGSBCIR7.js.map} +0 -0
- /package/dist/{tvs.categorical-ZTFJDJQU.js.map → tvs.categorical-RTSI5L6T.js.map} +0 -0
- /package/dist/{tvs.condition-DCDNI627.js.map → tvs.condition-VBDUN33K.js.map} +0 -0
- /package/dist/{tvs.dt-X6DES76X.js.map → tvs.dt-NP6556P7.js.map} +0 -0
- /package/dist/{tvs.dtcnv.categorical-UPRTUO7A.js.map → tvs.dtcnv.categorical-RERJRI5J.js.map} +0 -0
- /package/dist/{tvs.dtcnv.continuous-K3J5KKZD.js.map → tvs.dtcnv.continuous-UEVWYT3H.js.map} +0 -0
- /package/dist/{tvs.dtfusion-XV3UM2QG.js.map → tvs.dtfusion-CRJ77JUK.js.map} +0 -0
- /package/dist/{tvs.dtitd-LKYJG4XK.js.map → tvs.dtitd-ZOCNVICE.js.map} +0 -0
- /package/dist/{tvs.dtsnvindel-KFAQGI4H.js.map → tvs.dtsnvindel-LFWG54AQ.js.map} +0 -0
- /package/dist/{tvs.dtsv-4NV4DRWC.js.map → tvs.dtsv-SNIZC3C6.js.map} +0 -0
- /package/dist/{tvs.multivalue-WSSBQ7K4.js.map → tvs.multivalue-UJS4743S.js.map} +0 -0
- /package/dist/{tvs.numeric-OFA6L2TA.js.map → tvs.numeric-KKMUTKSJ.js.map} +0 -0
- /package/dist/{tvs.samplelst-W6QKXHGF.js.map → tvs.samplelst-AW3IY3CB.js.map} +0 -0
- /package/dist/{tvs.survival-ESWYE4QM.js.map → tvs.survival-LH2Z3WTM.js.map} +0 -0
- /package/dist/{tvs.termCollection-3GOKKMKB.js.map → tvs.termCollection-OQNMYVX5.js.map} +0 -0
- /package/dist/{vocabulary-6S6F2UAA.js.map → vocabulary-6XMG22NZ.js.map} +0 -0
- /package/dist/{wsi.direct-ZAOVMG5X.js.map → wsi.direct-EJ2ENH64.js.map} +0 -0
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const scctTerms = opts.app.vocabApi.termdbConfig?.termType2terms?.[TermTypeGroups.SINGLECELL_CELLTYPE];
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Blues_default,
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}
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const totalColgspace = s.colgspace * Math.max(0, this.visibleSampleGrps.size - 1);
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const tentativeGaps = this.sampleOrder.length * s.colspace + totalColgspace;
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const spacedColw = (this.availContentWidth - tentativeGaps) / this.sampleOrder.length;
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const constrainedMINCOLWSPACED = Math.max(s.colwMin, Math.min(MINCOLWSPACED, s.colwMax));
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colwSpaced = Math.max(constrainedMINCOLWSPACED, Math.min(spacedColw, s.colwMax));
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colwNoSpace = Math.max(s.colwMin, Math.min(noSpacedColw, s.colwMax));
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}
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const { colw } = this.computedSettings;
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this.computedSettings.colspace = colw === colwNoSpace && colwSpaced < colwNoSpace || colw * s.zoomLevel < MINCOLWSPACED ? 0 : s.colspace;
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const hch = this.state.config.settings.hierCluster?.yDendrogramHeight || 0;
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const availHeight = s.availContentHeight || screen.availHeight - hch;
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this.computedSettings.clusterRowh = Math.min(
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-
s.rowhMax,
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Math.max(s.rowhMin, Math.floor(availHeight / this.numClusterTerms))
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);
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copyMerge(this.settings.matrix, this.computedSettings);
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}
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function getMaxGrpLabelWidth() {
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const g = this.dom.svg.append("g").attr("opacity", 0.01);
|
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let maxWidth = 0;
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for (const grp of this.termGroups) {
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const grpLabel = !grp.name ? "" : grp.name.length <= s.termGrpLabelMaxChars ? grp.name : grp.name.slice(0, s.termGrpLabelMaxChars) + "\u2026";
|
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98
|
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const text = g.append("text").text(grpLabel).attr("font-size", 12);
|
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const box = text.node().getBBox();
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100
|
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if (maxWidth < box.width) maxWidth = box.width;
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}
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g.remove();
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return maxWidth;
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|
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}
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function setLabelsAndScales() {
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|
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this.cnvValues = [];
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const grpTotals = {};
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const processedLabels = { sampleGrpByName: {}, termGrpByName: {} };
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|
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let totalHtAdjustments = 0;
|
|
112
|
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for (const t of this.termOrder) {
|
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const countedSamples = /* @__PURE__ */ new Set();
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|
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t.counts = { samples: 0, hits: 0 };
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|
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const renderedContinuousVs = [];
|
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116
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let hasMixedValues = false;
|
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if (t.tw.term.type == "termCollection") {
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|
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}
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t.counts.subGroupCounts = {};
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122
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for (const group of this.sampleGroups) {
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t.counts.subGroupCounts[group.name] = {
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samplesTotal: 0,
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// number of counted (not Blank or WT) samples
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classes: {}
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};
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}
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}
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if (!processedLabels.termGrpByName[t.grp.name || ""]) {
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const name = t.grp.name || "";
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}
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for (const sample of this.sampleOrder) {
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139
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if (!(name in processedLabels.sampleGrpByName)) {
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sample.grp.label = name.length <= s.sampleGrpLabelMaxChars ? name : name.slice(0, s.sampleGrpLabelMaxChars) + "\u2026";
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processedLabels.sampleGrpByName[name] = sample.grp.label;
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}
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const sampleName = sample.row._ref_.label || "";
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sample.label = sampleName.length <= s.collabelmaxchars ? sampleName : sampleName.slice(0, s.collabelmaxchars) + "\u2026";
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const anno = sample.row[t.tw.$id];
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if (!anno) continue;
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if (t.tw.term.type == "termCollection" && anno.hasMixedValues) {
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hasMixedValues = true;
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}
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|
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if (t.tw.term.type == "termCollection" && anno.values) {
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|
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if (pct > 0) {
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|
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const cumSum = val.pre_val_sum + pct;
|
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|
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if (!("maxval" in t.counts) || t.counts.maxval < cumSum) {
|
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159
|
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t.counts.maxval = cumSum;
|
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160
|
-
}
|
|
161
|
-
} else if (pct < 0) {
|
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|
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const cumSum = val.pre_val_sum + pct;
|
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|
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if (!("minval" in t.counts) || t.counts.minval > cumSum) {
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|
164
|
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t.counts.minval = cumSum;
|
|
165
|
-
}
|
|
166
|
-
}
|
|
167
|
-
}
|
|
168
|
-
}
|
|
169
|
-
const { filteredValues, countedValues, renderedValues } = this.classifyValues(
|
|
170
|
-
anno,
|
|
171
|
-
t.tw,
|
|
172
|
-
t.grp,
|
|
173
|
-
this.settings.matrix,
|
|
174
|
-
sample.row
|
|
175
|
-
);
|
|
176
|
-
anno.filteredValues = filteredValues;
|
|
177
|
-
anno.countedValues = countedValues;
|
|
178
|
-
anno.renderedValues = renderedValues;
|
|
179
|
-
if (anno.countedValues?.length) {
|
|
180
|
-
t.counts.samples += 1;
|
|
181
|
-
t.counts.hits += anno.countedValues.length;
|
|
182
|
-
if (t.tw.q?.mode == "continuous") {
|
|
183
|
-
const v = anno.value;
|
|
184
|
-
if (!t.tw.term.values?.[v]?.uncomputable) {
|
|
185
|
-
if (!("minval" in t.counts) || t.counts.minval > v) t.counts.minval = v;
|
|
186
|
-
if (!("maxval" in t.counts) || t.counts.maxval < v) t.counts.maxval = v;
|
|
187
|
-
}
|
|
188
|
-
}
|
|
189
|
-
if (t.tw.term.type == "geneVariant" && anno.values) {
|
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190
|
-
for (const val of anno.values) {
|
|
191
|
-
if (val.dt == dtcnv && "value" in val && !s.ignoreCnvValues) {
|
|
192
|
-
const v = val.value;
|
|
193
|
-
this.cnvValues.push(v);
|
|
194
|
-
}
|
|
195
|
-
}
|
|
196
|
-
}
|
|
197
|
-
}
|
|
198
|
-
if (t.tw.q?.mode == "continuous" && renderedValues?.length && t.grp.type != "hierCluster") {
|
|
199
|
-
renderedContinuousVs.push(
|
|
200
|
-
t.tw.term.valueConversion ? t.tw.term.valueConversion.scaleFactor * (renderedValues[0].value || renderedValues[0]) : renderedValues[0].value || renderedValues[0]
|
|
201
|
-
);
|
|
202
|
-
}
|
|
203
|
-
const subGroup = t.counts.subGroupCounts?.[sample.grp.name];
|
|
204
|
-
const countedValuesNoSkip = anno.filteredValues.filter((v) => {
|
|
205
|
-
if (t.tw.term.type == "geneVariant") {
|
|
206
|
-
if (v.class == "WT" || v.class == "Blank") return false;
|
|
207
|
-
}
|
|
208
|
-
return true;
|
|
209
|
-
});
|
|
210
|
-
if (countedValuesNoSkip.length) {
|
|
211
|
-
if (t.tw.term.type == "geneVariant") {
|
|
212
|
-
let sampleCounted = false;
|
|
213
|
-
for (const countedValue of countedValuesNoSkip) {
|
|
214
|
-
if (s.geneVariantCountSamplesSkipMclass.includes(countedValue.class)) {
|
|
215
|
-
if (!subGroup.notTestedClasses) subGroup.notTestedClasses = {};
|
|
216
|
-
if (!(countedValue.class in subGroup.notTestedClasses)) subGroup.notTestedClasses[countedValue.class] = 1;
|
|
217
|
-
else subGroup.notTestedClasses[countedValue.class] += 1;
|
|
218
|
-
} else if (!(countedValue.class in subGroup.classes)) {
|
|
219
|
-
if (!sampleCounted) {
|
|
220
|
-
subGroup.samplesTotal += 1;
|
|
221
|
-
sampleCounted = true;
|
|
222
|
-
}
|
|
223
|
-
subGroup.classes[countedValue.class] = 1;
|
|
224
|
-
} else {
|
|
225
|
-
if (!sampleCounted) {
|
|
226
|
-
subGroup.samplesTotal += 1;
|
|
227
|
-
sampleCounted = true;
|
|
228
|
-
}
|
|
229
|
-
subGroup.classes[countedValue.class] += 1;
|
|
230
|
-
}
|
|
231
|
-
}
|
|
232
|
-
} else {
|
|
233
|
-
subGroup.samplesTotal += 1;
|
|
234
|
-
for (const countedValue of countedValuesNoSkip) {
|
|
235
|
-
if (!(countedValue in subGroup.classes)) subGroup.classes[countedValue] = 1;
|
|
236
|
-
else subGroup.classes[countedValue] += 1;
|
|
237
|
-
}
|
|
238
|
-
}
|
|
239
|
-
}
|
|
240
|
-
if (anno.filteredValues?.length && t.tw.term.type == "geneVariant") {
|
|
241
|
-
const notTested = anno.filteredValues.every((v) => v.class == "Blank");
|
|
242
|
-
if (notTested) {
|
|
243
|
-
subGroup.samplesNotTested += 1;
|
|
244
|
-
}
|
|
245
|
-
}
|
|
246
|
-
}
|
|
247
|
-
if (t.tw.label) {
|
|
248
|
-
t.label = t.tw.label;
|
|
249
|
-
} else if (t.grp.type == "hierCluster") {
|
|
250
|
-
t.label = t.tw.term.gene || t.tw.term.name;
|
|
251
|
-
} else if (t.tw.q?.variantFilter) {
|
|
252
|
-
const selected = variantFilterLabel(t.tw.q.variantFilter, this.mclass);
|
|
253
|
-
t.label = selected ? `${t.tw.term.name} ${selected}` : t.tw.term.name;
|
|
254
|
-
} else {
|
|
255
|
-
t.label = t.tw.term.name;
|
|
256
|
-
}
|
|
257
|
-
if (t.label.length > s.rowlabelmaxchars) t.label = t.label.slice(0, s.rowlabelmaxchars - 1) + "\u2026";
|
|
258
|
-
const termGroupName = this.config?.settings.hierCluster?.termGroupName;
|
|
259
|
-
if (s.samplecount4gene && t.tw.term.type.startsWith("gene") && (!termGroupName || t.grp.name !== termGroupName)) {
|
|
260
|
-
const count = s.samplecount4gene === "abs" ? t.counts.samples : (100 * t.counts.samples / this.sampleOrder.length).toFixed(1) + "%";
|
|
261
|
-
t.label = `${t.label} (${count})`;
|
|
262
|
-
}
|
|
263
|
-
const twSpecificSettings = this.config.settings.matrix.twSpecificSettings;
|
|
264
|
-
if (!twSpecificSettings[t.tw.$id]) twSpecificSettings[t.tw.$id] = {};
|
|
265
|
-
const twSettings = twSpecificSettings[t.tw.$id];
|
|
266
|
-
if (t.grp.type !== "hierCluster" && t.tw.q?.mode == "continuous") {
|
|
267
|
-
const vc = t.tw.term.valueConversion;
|
|
268
|
-
if (vc) {
|
|
269
|
-
t.counts.minval *= vc.scaleFactor;
|
|
270
|
-
t.counts.maxval *= vc.scaleFactor;
|
|
271
|
-
}
|
|
272
|
-
if (renderedContinuousVs.length && t.tw.q.convert2ZScore) {
|
|
273
|
-
const mean = renderedContinuousVs.reduce((acc, val) => acc + val, 0) / renderedContinuousVs.length;
|
|
274
|
-
const std = Math.sqrt(
|
|
275
|
-
renderedContinuousVs.reduce((acc, val) => acc + Math.pow(val - mean, 2), 0) / renderedContinuousVs.length
|
|
276
|
-
);
|
|
277
|
-
t.mean = mean;
|
|
278
|
-
t.std = std;
|
|
279
|
-
t.counts.minval = (t.counts.minval - mean) / std;
|
|
280
|
-
t.counts.maxval = (t.counts.maxval - mean) / std;
|
|
281
|
-
}
|
|
282
|
-
if (!twSettings.contBarH) twSettings.contBarH = t.tw.term.type == "termCollection" ? 150 : s.barh;
|
|
283
|
-
if (!("gap" in twSettings)) twSettings.contBarGap = 4;
|
|
284
|
-
const barh = twSettings.contBarH;
|
|
285
|
-
if (t.tw.term.type == "termCollection") {
|
|
286
|
-
if (!("minval" in t.counts)) t.counts.minval = 0;
|
|
287
|
-
if (!("maxval" in t.counts)) t.counts.maxval = 0;
|
|
288
|
-
}
|
|
289
|
-
const absMin = Math.abs(t.counts.minval);
|
|
290
|
-
const rangeSpansZero = t.counts.minval < 0 && t.counts.maxval > 0;
|
|
291
|
-
const ratio = t.counts.minval >= 0 ? 1 : t.counts.maxval / (absMin + t.counts.maxval);
|
|
292
|
-
t.counts.posMaxHt = ratio * barh;
|
|
293
|
-
const tickValues = [t.counts.maxval, t.counts.minval];
|
|
294
|
-
t.scales = {
|
|
295
|
-
tickValues,
|
|
296
|
-
full: linear().domain(tickValues).range([1, barh])
|
|
297
|
-
};
|
|
298
|
-
if (t.counts.maxval >= 0) {
|
|
299
|
-
const domainMin = rangeSpansZero ? 0 : t.counts.minval;
|
|
300
|
-
t.scales.pos = linear().domain([domainMin, t.counts.maxval]).range([1, t.counts.posMaxHt]);
|
|
301
|
-
}
|
|
302
|
-
if (t.counts.minval < 0) {
|
|
303
|
-
const domainMax = rangeSpansZero ? 0 : t.counts.maxval;
|
|
304
|
-
t.scales.neg = linear().domain([domainMax, t.counts.minval]).range([1, barh - t.counts.posMaxHt]);
|
|
305
|
-
}
|
|
306
|
-
}
|
|
307
|
-
t.totalHtAdjustments = totalHtAdjustments;
|
|
308
|
-
t.rowHt = t.grp.type == "hierCluster" ? s.clusterRowh : twSettings.contBarH && t.tw.q?.mode == "continuous" ? twSettings.contBarH + 2 * twSettings.contBarGap : ht;
|
|
309
|
-
const adjustment = t.rowHt - ht - (t.grp.type == "hierCluster" ? s.rowspace : 0);
|
|
310
|
-
totalHtAdjustments += adjustment;
|
|
311
|
-
t.cumulativeAdjustment = totalHtAdjustments;
|
|
312
|
-
if (!(t.visibleGrpIndex in grpTotals)) grpTotals[t.visibleGrpIndex] = { htAdjustment: 0 };
|
|
313
|
-
grpTotals[t.visibleGrpIndex].htAdjustment += adjustment;
|
|
314
|
-
t.grpTotals = grpTotals[t.visibleGrpIndex];
|
|
315
|
-
}
|
|
316
|
-
let cnvLegendDomainRange;
|
|
317
|
-
if (this.cnvValues.length) {
|
|
318
|
-
if (s.cnvValues.cutoffMode == "fixed") {
|
|
319
|
-
this.cnvValues = this.cnvValues.filter((v) => v >= s.cnvValues.min && v <= s.cnvValues.max).sort((a, b) => a - b);
|
|
320
|
-
if (this.cnvValues[0] != s.cnvValues.min) this.cnvValues.unshift(s.cnvValues.min);
|
|
321
|
-
if (this.cnvValues[this.cnvValues.length - 1] != s.cnvValues.max) this.cnvValues.push(s.cnvValues.max);
|
|
322
|
-
} else if (s.cnvValues.cutoffMode == "percentile" || s.cnvValues.cutoffMode == "auto") {
|
|
323
|
-
let maxPercentile = s.cnvValues.cutoffMode == "auto" ? s.cnvValues.defaultPercentile : s.cnvValues.percentile;
|
|
324
|
-
maxPercentile = maxPercentile / 100;
|
|
325
|
-
const minPercentile = roundValueAuto(1 - maxPercentile);
|
|
326
|
-
this.cnvValues = removeOutliers(this.cnvValues, { minPercentile, maxPercentile, baseValue: 0 });
|
|
327
|
-
} else throw new Error(`Invalid cnvValues cutoffMode: ${s.cnvValues.cutoffMode}`);
|
|
328
|
-
const minLoss = this.cnvValues[0] <= 0 ? this.cnvValues[0] : void 0;
|
|
329
|
-
const maxGain = this.cnvValues[this.cnvValues.length - 1] >= 0 ? this.cnvValues[this.cnvValues.length - 1] : void 0;
|
|
330
|
-
let maxLoss, minGain, absMax;
|
|
331
|
-
for (const n of this.cnvValues) {
|
|
332
|
-
if (n < 0) maxLoss = n;
|
|
333
|
-
if (!minGain && n > 0) {
|
|
334
|
-
minGain = n;
|
|
335
|
-
break;
|
|
336
|
-
}
|
|
337
|
-
}
|
|
338
|
-
for (const t of this.termOrder) {
|
|
339
|
-
if (t.tw.term.type == "geneVariant") {
|
|
340
|
-
if (!cnvLegendDomainRange) {
|
|
341
|
-
const loss0color = Blues_default(0);
|
|
342
|
-
const gain0color = Reds_default(0);
|
|
343
|
-
const colorDiff = colorDelta(loss0color, gain0color);
|
|
344
|
-
if (minLoss !== void 0 && maxGain !== void 0 && colorDiff > 25)
|
|
345
|
-
console.warn(
|
|
346
|
-
`CNV loss and gain do not have the same middle color for value=0'${loss0color}' vs '${gain0color}', color difference=${colorDiff}`
|
|
347
|
-
);
|
|
348
|
-
absMax = minLoss !== void 0 && maxGain !== void 0 ? Math.max(Math.abs(minLoss), maxGain) : minLoss !== void 0 ? Math.abs(minLoss) : maxGain;
|
|
349
|
-
cnvLegendDomainRange = getInterpolatedDomainRange({
|
|
350
|
-
absMin: 0,
|
|
351
|
-
absMax,
|
|
352
|
-
totalNumSteps: 10,
|
|
353
|
-
negInterpolator: minLoss !== void 0 && Blues_default,
|
|
354
|
-
posInterpolator: maxGain !== void 0 && Reds_default,
|
|
355
|
-
// force this middleColor to white, knowing that interpolateBlues and interpolateReds,
|
|
356
|
-
// as hardcoded above and below, share similar white colors for their minimum abs values
|
|
357
|
-
middleColor: "white"
|
|
358
|
-
});
|
|
359
|
-
}
|
|
360
|
-
t.scales = {
|
|
361
|
-
loss: Blues_default,
|
|
362
|
-
gain: Reds_default,
|
|
363
|
-
maxLoss,
|
|
364
|
-
maxGain,
|
|
365
|
-
minLoss,
|
|
366
|
-
minGain,
|
|
367
|
-
absMax,
|
|
368
|
-
legend: cnvLegendDomainRange
|
|
369
|
-
};
|
|
370
|
-
}
|
|
371
|
-
}
|
|
372
|
-
}
|
|
373
|
-
}
|
|
374
|
-
function setLayout() {
|
|
375
|
-
const s = this.settings.matrix;
|
|
376
|
-
const [col, row] = !s.transpose ? ["sample", "term"] : ["term", "sample"];
|
|
377
|
-
const [_t_, _b_] = s.collabelpos == "top" ? ["", "Grp"] : ["Grp", ""];
|
|
378
|
-
const [_l_, _r_] = s.rowlabelpos == "left" ? ["", "Grp"] : ["Grp", ""];
|
|
379
|
-
const top = col + _t_;
|
|
380
|
-
const btm = col + _b_;
|
|
381
|
-
const left = row + _l_;
|
|
382
|
-
const right = row + _r_;
|
|
383
|
-
this.samples = this.sampleOrder;
|
|
384
|
-
this.sampleGrps = this.sampleOrder.filter((s2) => s2.index === 0);
|
|
385
|
-
this.terms = this.termOrder;
|
|
386
|
-
this.termGrps = this.termOrder.filter((t) => t.index === 0);
|
|
387
|
-
const layout = {};
|
|
388
|
-
const sides = { top, btm, left, right };
|
|
389
|
-
for (const direction in sides) {
|
|
390
|
-
const d = sides[direction];
|
|
391
|
-
const Direction = direction[0].toUpperCase() + direction.slice(1);
|
|
392
|
-
layout[direction] = {
|
|
393
|
-
prefix: d,
|
|
394
|
-
data: this[`${d}s`],
|
|
395
|
-
offset: s[`${d}LabelOffset`],
|
|
396
|
-
box: this.dom[`${d}LabelG`],
|
|
397
|
-
key: this[`${d}Key`],
|
|
398
|
-
label: this[`${d}Label`],
|
|
399
|
-
render: this[`render${Direction}Label`],
|
|
400
|
-
isGroup: sides[direction].includes("Grp")
|
|
401
|
-
};
|
|
402
|
-
}
|
|
403
|
-
const yOffset = layout.top.offset + s.margin.top + s.scrollHeight;
|
|
404
|
-
const xOffset = layout.left.offset + s.margin.left;
|
|
405
|
-
this.setAutoDimensions(xOffset);
|
|
406
|
-
this.setLabelsAndScales();
|
|
407
|
-
const colw = Math.max(s.colwMin, Math.min(s.colwMax, s.colw * s.zoomLevel));
|
|
408
|
-
const dx = colw + s.colspace;
|
|
409
|
-
const nx = this[`${col}s`].length;
|
|
410
|
-
const dy = s.rowh + s.rowspace;
|
|
411
|
-
const ny = this[`${row}s`].length;
|
|
412
|
-
const mainwByColDimensions = nx * (colw + s.colspace) + this[`${col}Grps`].length * s.colgspace + (this[`${col}s`].slice(-1)[0]?.totalHtAdjustments || 0);
|
|
413
|
-
const mainw = Math.min(mainwByColDimensions, this.availContentWidth);
|
|
414
|
-
const lastRow = this[`${row}s`].slice(-1)[0];
|
|
415
|
-
const mainh = ny * dy + (this[`${row}Grps`].length - 1) * s.rowgspace + (lastRow?.cumulativeAdjustment || 0);
|
|
416
|
-
const colLabelFontSize = Math.min(
|
|
417
|
-
Math.max(colw + s.colspace - 2 * s.collabelpad - s.colspace, s.minLabelFontSize),
|
|
418
|
-
s.maxLabelFontSize
|
|
419
|
-
);
|
|
420
|
-
const topFontSize = _t_ == "Grp" ? s.grpLabelFontSize : colLabelFontSize;
|
|
421
|
-
layout.top.attr = {
|
|
422
|
-
boxTransform: `translate(${xOffset}, ${yOffset - s.collabelgap})`,
|
|
423
|
-
adjustBoxTransform: (dx2) => layout.top.box.attr("transform", `translate(${xOffset + dx2}, ${yOffset - s.collabelgap})`),
|
|
424
|
-
labelTransform: "rotate(-90)",
|
|
425
|
-
labelAnchor: "start",
|
|
426
|
-
labelGY: 0,
|
|
427
|
-
labelGTransform: this[`col${_t_}LabelGTransform`],
|
|
428
|
-
fontSize: topFontSize,
|
|
429
|
-
textpos: { coord: "y", factor: -1 },
|
|
430
|
-
axisFxn: axisTop
|
|
431
|
-
};
|
|
432
|
-
if (layout.top.prefix == "sample")
|
|
433
|
-
layout.top.display = s.sampleLabelsToggle !== "hide" && colw >= s.minLabelFontSize ? "" : "none";
|
|
434
|
-
const btmFontSize = _b_ == "Grp" ? s.grpLabelFontSize : colLabelFontSize;
|
|
435
|
-
layout.btm.attr = {
|
|
436
|
-
boxTransform: `translate(${xOffset}, ${yOffset + mainh + s.collabelgap})`,
|
|
437
|
-
adjustBoxTransform: (dx2) => layout.btm.box.attr("transform", `translate(${xOffset + dx2}, ${yOffset + mainh + s.collabelgap})`),
|
|
438
|
-
labelTransform: "rotate(-90)",
|
|
439
|
-
labelAnchor: "end",
|
|
440
|
-
labelGY: 0,
|
|
441
|
-
labelGTransform: this[`col${_b_}LabelGTransform`],
|
|
442
|
-
fontSize: btmFontSize,
|
|
443
|
-
textpos: { coord: "y", factor: 1 },
|
|
444
|
-
axisFxn: axisBottom
|
|
445
|
-
};
|
|
446
|
-
if (layout.btm.prefix == "sample")
|
|
447
|
-
layout.btm.display = s.sampleLabelsToggle !== "hide" && colw >= s.minLabelFontSize ? "" : "none";
|
|
448
|
-
const leftFontSize = _l_ == "Grp" ? s.grpLabelFontSize : Math.max(s.rowh + s.rowspace - 2 * s.rowlabelpad - s.rowspace, s.minLabelFontSize);
|
|
449
|
-
layout.left.attr = {
|
|
450
|
-
boxTransform: `translate(${xOffset - s.rowlabelgap}, ${yOffset})`,
|
|
451
|
-
labelTransform: "",
|
|
452
|
-
labelAnchor: "end",
|
|
453
|
-
labelGX: 0,
|
|
454
|
-
labelGTransform: this[`row${_l_}LabelGTransform`],
|
|
455
|
-
fontSize: leftFontSize,
|
|
456
|
-
textpos: { coord: "x", factor: -1 },
|
|
457
|
-
axisFxn: axisLeft
|
|
458
|
-
};
|
|
459
|
-
const rtFontSize = _r_ == "Grp" ? s.grpLabelFontSize : Math.max(s.rowh + s.rowspace - 2 * s.rowlabelpad, s.minLabelFontSize);
|
|
460
|
-
layout.right.attr = {
|
|
461
|
-
boxTransform: `translate(${xOffset + mainw + s.rowlabelgap}, ${yOffset})`,
|
|
462
|
-
labelTransform: "",
|
|
463
|
-
labelAnchor: "start",
|
|
464
|
-
labelGX: 0,
|
|
465
|
-
labelGTransform: this[`row${_r_}LabelGTransform`],
|
|
466
|
-
fontSize: rtFontSize,
|
|
467
|
-
textpos: { coord: "x", factor: 1 },
|
|
468
|
-
axisFxn: axisRight
|
|
469
|
-
};
|
|
470
|
-
this.dom.sampleLabelsPG.attr("clip-path", s.transpose ? "" : `url(#${this.seriesClipId})`);
|
|
471
|
-
this.dom.termLabelsPG.attr("clip-path", s.transpose ? `url(#${this.seriesClipId})` : "");
|
|
472
|
-
this.layout = layout;
|
|
473
|
-
if (!s.zoomCenterPct) {
|
|
474
|
-
s.zoomCenterPct = 0.5;
|
|
475
|
-
s.zoomIndex = Math.round(s.zoomCenterPct * mainw / dx);
|
|
476
|
-
s.zoomGrpIndex = this.sampleOrder[s.zoomIndex]?.grpIndex || 0;
|
|
477
|
-
}
|
|
478
|
-
const zoomCenter = s.zoomCenterPct * mainw;
|
|
479
|
-
const centerCellX = s.zoomIndex * dx + s.zoomGrpIndex * s.colgspace;
|
|
480
|
-
const zoomedMainW = Math.max(0, nx * dx + (this[`${col}Grps`].length - 1) * s.colgspace);
|
|
481
|
-
const seriesXoffset = s.zoomLevel <= 1 && mainw >= zoomedMainW ? 0 : Math.max(zoomCenter - centerCellX, mainw - zoomedMainW);
|
|
482
|
-
const imgW = (s.imgWMax > zoomedMainW ? zoomedMainW : s.imgWMax) - 1e-7;
|
|
483
|
-
const halfImgW = 0.5 * imgW;
|
|
484
|
-
const unwantedRightOvershoot = Math.max(0, centerCellX + halfImgW - zoomedMainW);
|
|
485
|
-
const imgLeftMin = Math.max(0, centerCellX - Math.min(halfImgW, imgW) - unwantedRightOvershoot);
|
|
486
|
-
const xMin = s.zoomLevel <= 1 && mainw >= zoomedMainW ? 0 : imgLeftMin;
|
|
487
|
-
const xMax = imgW + xMin;
|
|
488
|
-
this.dimensions = {
|
|
489
|
-
xMin,
|
|
490
|
-
xMax,
|
|
491
|
-
dx,
|
|
492
|
-
dy,
|
|
493
|
-
xOffset,
|
|
494
|
-
yOffset,
|
|
495
|
-
mainw,
|
|
496
|
-
mainh,
|
|
497
|
-
colw,
|
|
498
|
-
zoomedMainW,
|
|
499
|
-
seriesXoffset: seriesXoffset > 0 ? 0 : seriesXoffset,
|
|
500
|
-
maxMainW: Math.max(mainwByColDimensions, this.availContentWidth),
|
|
501
|
-
imgW,
|
|
502
|
-
// recompute the resolvable "pixel width", in case the pixel ratio changes
|
|
503
|
-
// when moving the browser window to a different monitor,
|
|
504
|
-
// will be used to sharpen canvas shapes that are smaller than this pixel width
|
|
505
|
-
pxw: 1 / window.devicePixelRatio
|
|
506
|
-
};
|
|
507
|
-
}
|
|
508
|
-
|
|
509
|
-
export {
|
|
510
|
-
setAutoDimensions,
|
|
511
|
-
getMaxGrpLabelWidth,
|
|
512
|
-
setLabelsAndScales,
|
|
513
|
-
setLayout,
|
|
514
|
-
matrix_layout_exports
|
|
515
|
-
};
|
|
516
|
-
//# sourceMappingURL=chunk-PMLMXEER.js.map
|