@sjcrh/proteinpaint-client 2.216.0 → 2.217.0
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/2dmaf-RRHATFHO.js +1362 -0
- package/dist/AggMatrixInput-4UHBCXYH.js +402 -0
- package/dist/AggregateMatrix-IJE5CM5Y.js +37 -0
- package/dist/AppHeader-UXGLRW6C.js +826 -0
- package/dist/BoxPlot-GQYC22KY.js +1233 -0
- package/dist/CorrelationVolcano-5CWRWZTI.js +613 -0
- package/dist/Cuminc-TYHKAPRK.js +1217 -0
- package/dist/DE-UUFQGSOI.js +85 -0
- package/dist/DEinput-DU7MF4YY.js +497 -0
- package/dist/DM-SSI5KUBC.js +86 -0
- package/dist/DifferentialAnalysis-G6FE2MXY.js +235 -0
- package/dist/Disco-B3KGNEAW.js +3384 -0
- package/dist/Disco.UI-UNPUBQCN.js +239 -0
- package/dist/DmrPlot-27NGDMT4.js +358 -0
- package/dist/GB-SXACUA4V.js +1388 -0
- package/dist/GSEA-EHMBA3TF.js +870 -0
- package/dist/GeneExpInput-NDXISF2U.js +38 -0
- package/dist/Geomap-3CNT227W.js +80 -0
- package/dist/HicApp-VQBUB6EZ.js +2240 -0
- package/dist/IDCViewer-DTOE7KDX.js +10808 -0
- package/dist/NumBinaryEditor-IVZ4MMQT.js +274 -0
- package/dist/NumBinaryEditor.unit.spec-3BSQ6FM4.js +308 -0
- package/dist/NumContEditor-CUZHU3IO.js +100 -0
- package/dist/NumContEditor.unit.spec-SCQFD2Y7.js +160 -0
- package/dist/NumCustomBinEditor-UEEYZ4ZO.js +29 -0
- package/dist/NumCustomBinEditor.unit.spec-GYS35OQV.js +393 -0
- package/dist/NumDiscreteEditor-IT7NIXTV.js +165 -0
- package/dist/NumDiscreteEditor.unit.spec-LB6VLAWO.js +229 -0
- package/dist/NumRegularBinEditor-FF6UXZWN.js +29 -0
- package/dist/NumRegularBinEditor.unit.spec-Z4S5LH2C.js +274 -0
- package/dist/NumSplineEditor-IW5WEN3P.js +205 -0
- package/dist/NumSplineEditor.unit.spec-PAEN3SAD.js +220 -0
- package/dist/NumericDensity-CPJIQLYT.js +29 -0
- package/dist/NumericDensity.unit.spec-4KHECHVU.js +414 -0
- package/dist/NumericHandler-SEFTQJDM.js +30 -0
- package/dist/NumericHandler.unit.spec-UGDR3476.js +210 -0
- package/dist/ProteomeInput-NYPUYVN5.js +610 -0
- package/dist/ProteomeInput-NYPUYVN5.js.map +7 -0
- package/dist/Regression-WDSISHYL.js +1412 -0
- package/dist/RunChart2-2NPADXUR.js +744 -0
- package/dist/SC-EWDBPHEL.js +1344 -0
- package/dist/Violin-POGGPCZY.js +1095 -0
- package/dist/Volcano-U2B4KEUL.js +2452 -0
- package/dist/Wsi-G7OCAJ3R.js +625 -0
- package/dist/adSandbox-SUCX6DAQ.js +29 -0
- package/dist/animatedBubbleChart-SDBWJELZ.js +542 -0
- package/dist/app-ATQM5PKI.js +28 -0
- package/dist/app-BCKEWJCY.js +38 -0
- package/dist/app.js +14 -14
- package/dist/bam-QK2ZLZDI.js +872 -0
- package/dist/barchart-RHDKI3NZ.js +38 -0
- package/dist/barchart2-CS3E6FOY.js +305 -0
- package/dist/block-RQ3HTJVP.js +6232 -0
- package/dist/block.init-T33F47DO.js +29 -0
- package/dist/block.mds.expressionrank-LQD6MN6Z.js +350 -0
- package/dist/block.mds.geneboxplot-N5XHHVR7.js +819 -0
- package/dist/block.mds.junction-JD4WQUSH.js +1534 -0
- package/dist/block.mds.svcnv-LCTYWXL2.js +6408 -0
- package/dist/block.svg-2F3RGTI3.js +155 -0
- package/dist/block.tk.aicheck-BOF6WZ5E.js +274 -0
- package/dist/block.tk.bam-5GBYEQBM.js +1897 -0
- package/dist/block.tk.bedgraphdot-LVQEP4RS.js +375 -0
- package/dist/block.tk.bigwig.ui-HHBO4JAC.js +202 -0
- package/dist/block.tk.hicstraw-JBO4UEOA.js +814 -0
- package/dist/block.tk.junction-S5S2N7FK.js +2353 -0
- package/dist/block.tk.junction.textmatrixui-DNQL7WB5.js +190 -0
- package/dist/block.tk.ld-JHQNR67E.js +90 -0
- package/dist/block.tk.menu-7JBJOY2O.js +1050 -0
- package/dist/block.tk.pgv-FQPREV6P.js +934 -0
- package/dist/brainImaging-HEWGZZNY.js +550 -0
- package/dist/brainRegions-QUGB7YUW.js +213 -0
- package/dist/bubbleHeatmap-OZRONGAX.js +374 -0
- package/dist/cellTypeBubbleHeatmap-N7NDE325.js +274 -0
- package/dist/chunk-2FWSNJEN.js +54 -0
- package/dist/chunk-2JIKMCJR.js +34 -0
- package/dist/chunk-3SPEW6R6.js +102 -0
- package/dist/chunk-5G6O5RYM.js +123 -0
- package/dist/chunk-65DO5IKM.js +299 -0
- package/dist/chunk-6D4HOTG7.js +1844 -0
- package/dist/chunk-6D4HOTG7.js.map +7 -0
- package/dist/chunk-6Q5SOSSU.js +2685 -0
- package/dist/chunk-7JHIUS54.js +626 -0
- package/dist/chunk-7X347XMF.js +397 -0
- package/dist/chunk-ABLG7GUS.js +55 -0
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- package/dist/chunk-GDHQVEIO.js +217 -0
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- package/dist/chunk-HFKZGMVV.js +839 -0
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- package/dist/chunk-HWNQOADC.js.map +7 -0
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- package/dist/chunk-L2WOLNZK.js +339 -0
- package/dist/chunk-LQKMDIRB.js +466 -0
- package/dist/chunk-LSQ5AQ6Q.js +562 -0
- package/dist/chunk-MBQIHLGI.js +1269 -0
- package/dist/chunk-MFR4WWDM.js +14 -0
- package/dist/chunk-MU4Z2MX2.js +340 -0
- package/dist/chunk-MU4Z2MX2.js.map +7 -0
- package/dist/chunk-NHMIMTJA.js +281 -0
- package/dist/chunk-NNDKYTUV.js +25353 -0
- package/dist/chunk-NNDKYTUV.js.map +7 -0
- package/dist/chunk-NPBN3PPZ.js +6358 -0
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- package/dist/chunk-NYO7YANQ.js +294 -0
- package/dist/chunk-OBNHXAYG.js +194 -0
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- package/dist/chunk-WU3YXPRE.js +217 -0
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- package/dist/chunk-ZPWBYHNE.js +5799 -0
- package/dist/chunk-ZPWBYHNE.js.map +7 -0
- package/dist/chunk-ZX75ZAUG.js +45 -0
- package/dist/chunk-ZX75ZAUG.js.map +7 -0
- package/dist/cohort-ATIZW34H.js +66 -0
- package/dist/cohortSunburst-WQK2UV25.js +686 -0
- package/dist/cohortSunburst-WQK2UV25.js.map +7 -0
- package/dist/condition-SGJIDZNB.js +323 -0
- package/dist/controls-JQCMGPXP.js +30 -0
- package/dist/controls.config-WQHVQAIJ.js +30 -0
- package/dist/correlation-S3MN3L5Q.js +91 -0
- package/dist/customdata.inputui-LGTGMJBZ.js +280 -0
- package/dist/dataDownload-FAWN2WKE.js +325 -0
- package/dist/databrowser.ui-KF3LWQXG.js +421 -0
- package/dist/dictionary-EVLEOT72.js +109 -0
- package/dist/dnaMethylation-J3SPEM4S.js +29 -0
- package/dist/dnaMethylation.integration.spec-CTA53YCT.js +194 -0
- package/dist/dofetch-3C3MI5NR.js +47 -0
- package/dist/e2pca-PTWPY5WP.js +340 -0
- package/dist/ep-MS4LQQDR.js +1245 -0
- package/dist/expclust.gdc.spec-S5FE4MMD.js +298 -0
- package/dist/facet-FSOIZJCA.js +515 -0
- package/dist/gb-YDEOK7NW.js +77 -0
- package/dist/geneExpClustering-37JKKFW3.js +240 -0
- package/dist/geneExpression-G6ODP3VY.js +29 -0
- package/dist/geneExpression-VQPRFNKE.js +309 -0
- package/dist/geneExpression.unit.spec-ZHXCUG6Q.js +124 -0
- package/dist/geneORA-E3PSS3CI.js +269 -0
- package/dist/geneRanking-MK3YYINC.js +544 -0
- package/dist/geneVariant-LEMAVFOY.js +32 -0
- package/dist/geneVariant-NNSB7JLS.js +285 -0
- package/dist/geneVariant.integration.spec-6CC5UAOP.js +499 -0
- package/dist/genefusion.ui-5NCQIQPN.js +299 -0
- package/dist/geneset-ZX4V3CFB.js +199 -0
- package/dist/genomeBrowser.spec-J7ISXY6H.js +272 -0
- package/dist/grin2-GN3DQNON.js +945 -0
- package/dist/grin2-LBGBBB4L.js +66 -0
- package/dist/hierCluster-5JURTKAZ.js +55 -0
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- package/dist/hierCluster.config-4EERP4KK.js +32 -0
- package/dist/hierCluster.integration.spec-VR4GULRV.js +479 -0
- package/dist/hierCluster.interactivity-SMTQOKUY.js +45 -0
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- package/dist/imagePlot-4LMIKBVE.js +152 -0
- package/dist/importPlot-3CG6ASNH.js +8 -0
- package/dist/isoformExpression-VCDNKTZ6.js +31 -0
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- package/dist/junction-5DXJO4PS.js +32 -0
- package/dist/junction.customTerm-UOPUSEOE.js +15 -0
- package/dist/junction.unit.spec-F35E3GJW.js +178 -0
- package/dist/launch.adhoc-V2HTCQGD.js +33 -0
- package/dist/leftlabel.sample-V7O2EC36.js +253 -0
- package/dist/lollipop-RNRZLG64.js +162 -0
- package/dist/maf-W6SF6BJS.js +451 -0
- package/dist/maftimeline-NABCAMHG.js +583 -0
- package/dist/matrix-JC6AJT2N.js +55 -0
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- package/dist/mavb-MRCVMBPD.js +723 -0
- package/dist/mds.fimo-5DCH5BEM.js +509 -0
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- package/dist/oncomatrix-R32ZPMX7.js +286 -0
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- package/dist/proteinView-FCPWJLGU.js +1346 -0
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- package/dist/proteomeCohortCompare-TYYUF5A5.js +866 -0
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- package/dist/sampleView-BUMMYRHJ.js +39 -0
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- /package/dist/{profileForms-FM7D4WO2.js.map → profileForms-2USYOA34.js.map} +0 -0
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- /package/dist/{pseudobulk-NIX4JOOZ.js.map → pseudobulk-ZIN5VJGB.js.map} +0 -0
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- /package/dist/{qualitative-GLTKWA6H.js.map → qualitative-N4F6NITI.js.map} +0 -0
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- /package/dist/{report-YPIAIMND.js.map → report-3Y2OWDF7.js.map} +0 -0
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- /package/dist/{samplelst-F2SLVHFP.js.map → samplelst-BWK53BLI.js.map} +0 -0
- /package/dist/{samplematrix-Z6F4F7YN.js.map → samplematrix-RQU43UYR.js.map} +0 -0
- /package/dist/{sc-UM7SEGED.js.map → sc-LCBFWCZZ.js.map} +0 -0
- /package/dist/{scatter-63XRRLGP.js.map → scatter-6S5I7OW3.js.map} +0 -0
- /package/dist/{scatter-HFTYLGDP.js.map → scatter-MJELX75N.js.map} +0 -0
- /package/dist/{selectGenomeWithTklst-PJNALPM2.js.map → selectGenomeWithTklst-WAVXHXR5.js.map} +0 -0
- /package/dist/{singleCellCellType-HR3R6KBD.js.map → singleCellCellType-WMCAJ7JF.js.map} +0 -0
- /package/dist/{singleCellCellType.unit.spec-VK57HQ2O.js.map → singleCellCellType.unit.spec-4Z46ZT5Q.js.map} +0 -0
- /package/dist/{singleCellGeneExpression-VWOA7MLN.js.map → singleCellGeneExpression-7Q5ZJT4R.js.map} +0 -0
- /package/dist/{singleCellGeneExpression.unit.spec-YP64T3XD.js.map → singleCellGeneExpression.unit.spec-6C7PDGRH.js.map} +0 -0
- /package/dist/{singleCellNumericValue-3VIUPYPB.js.map → singleCellNumericValue-QGYITZRC.js.map} +0 -0
- /package/dist/{singleCellNumericValue.unit.spec-VR5ICRQA.js.map → singleCellNumericValue.unit.spec-MQUKPEZJ.js.map} +0 -0
- /package/dist/{singleCellPlot-36QDY7VL.js.map → singleCellPlot-JJMFJ2KQ.js.map} +0 -0
- /package/dist/{singlecell-EXEOLJ3J.js.map → singlecell-J23S3JR2.js.map} +0 -0
- /package/dist/{singlecell-D2MZVFR4.js.map → singlecell-Y4OGUWEC.js.map} +0 -0
- /package/dist/{snp-XHEHXZMB.js.map → snp-IO6TKWGD.js.map} +0 -0
- /package/dist/{snp.unit.spec-YR6IDLL7.js.map → snp.unit.spec-X7ILEEPO.js.map} +0 -0
- /package/dist/{snplocus-BM7LUK2U.js.map → snplocus-Z2NGIKMO.js.map} +0 -0
- /package/dist/{snplst-22VSEZ7R.js.map → snplst-XCS2FCQV.js.map} +0 -0
- /package/dist/{spliceevent.a53ss.diagram-KERTJ3QA.js.map → spliceevent.a53ss.diagram-F3S4BRVG.js.map} +0 -0
- /package/dist/{spliceevent.exonskip.diagram-K74VIUA4.js.map → spliceevent.exonskip.diagram-AXCDJKH4.js.map} +0 -0
- /package/dist/{spliceevent.noeventdiagram-W7WGSVVL.js.map → spliceevent.noeventdiagram-UK3X667E.js.map} +0 -0
- /package/dist/{ssGSEA-XDEA5TVX.js.map → ssGSEA-ZRPNQKJ5.js.map} +0 -0
- /package/dist/{ssGSEA.unit.spec-RDCPXJ5S.js.map → ssGSEA.unit.spec-DG5ZHLC7.js.map} +0 -0
- /package/dist/{stattable-HZ3DOUEM.js.map → stattable-XYSC3CYU.js.map} +0 -0
- /package/dist/{summarizeCnvGeneexp-VB4SOJHT.js.map → summarizeCnvGeneexp-H2NP7VLU.js.map} +0 -0
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this.dom.topDendrogram = this.dom.svg.insert("g", "g").attr("clip-path", `url(#${this.hcClipId})`).append("g").attr("class", "sjpp-matrix-dendrogram").attr("data-testid", "hierCluster_top_dendrogram").on("click", (event) => {
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});
|
|
64
|
-
this.dom.leftDendrogram = this.dom.svg.insert("g", "g").attr("class", "sjpp-matrix-dendrogram").attr("data-testid", "hierCluster_left_dendrogram").on("click", (event) => {
|
|
65
|
-
const clickedLeftClusterId = this.getClusterFromLeftDendrogram(event);
|
|
66
|
-
if (clickedLeftClusterId) {
|
|
67
|
-
this.clickedLeftClusterIds = this.getAllChildrenClusterIds(clickedLeftClusterId, true);
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|
68
|
-
this.clickedLeftClusterIds.push(clickedLeftClusterId);
|
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69
|
-
const clickedLeftCluster = this.hierClusterData.clustering.row.mergedClusters.get(clickedLeftClusterId);
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70
|
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const clickedLeftClusterRowsNames = clickedLeftCluster.children.map((c) => c.name);
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71
|
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this.addSelectedRowsOptions(clickedLeftClusterRowsNames, event);
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72
|
-
} else {
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73
|
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delete this.clickedLeftClusterIds;
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74
|
-
}
|
|
75
|
-
if (this.clickedClusterIds) {
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76
|
-
delete this.clickedClusterIds;
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|
77
|
-
this.plotDendrogramHclust();
|
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78
|
-
} else this.plotDendrogramHclust("left");
|
|
79
|
-
});
|
|
80
|
-
}
|
|
81
|
-
async setHierClusterData(_data = {}) {
|
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82
|
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this.prevServerData = this.currServerData;
|
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83
|
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const [d, twlst] = await this.requestData({});
|
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84
|
-
if (d.error) throw d.error;
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|
85
|
-
this.currServerData = structuredClone(d);
|
|
86
|
-
if (!deepEqual(this.prevServerData, this.currServerData)) {
|
|
87
|
-
delete this.clickedClusterIds;
|
|
88
|
-
delete this.clickedLeftClusterIds;
|
|
89
|
-
}
|
|
90
|
-
const s = this.settings.hierCluster;
|
|
91
|
-
if (!d.clustering) {
|
|
92
|
-
if (d.gene) {
|
|
93
|
-
throw `Cannot do clustering: data is only available for 1 gene (${d.gene}). Try again by adding more genes.`;
|
|
94
|
-
}
|
|
95
|
-
}
|
|
96
|
-
this.hierClusterData = d;
|
|
97
|
-
const c = this.hierClusterData.clustering;
|
|
98
|
-
this.setHierColorScale(c);
|
|
99
|
-
const samples = {};
|
|
100
|
-
for (const [i, column] of c.col.order.entries()) {
|
|
101
|
-
samples[column.name] = { sample: column.name };
|
|
102
|
-
for (const [j, row] of c.row.order.entries()) {
|
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103
|
-
const tw = twlst.find((tw2) => tw2.$id === row.name || tw2.id === row.name);
|
|
104
|
-
const value = c.matrix[j][i];
|
|
105
|
-
samples[column.name][tw.$id] = {
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|
106
|
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key: tw.term.name,
|
|
107
|
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values: [
|
|
108
|
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{
|
|
109
|
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sample: column.name,
|
|
110
|
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dt: TermTypes2Dt[this.state.config.dataType],
|
|
111
|
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label: s.termGroupName,
|
|
112
|
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// gene: tw.term.name,
|
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113
|
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// chr: tw.term.chr,
|
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114
|
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// pos: `${tw.term.start}-${tw.term.stop}`,
|
|
115
|
-
value
|
|
116
|
-
// the color will be computed in matrix.cells, so that
|
|
117
|
-
// it can get updated even when there are no nonsetting state diff
|
|
118
|
-
}
|
|
119
|
-
]
|
|
120
|
-
};
|
|
121
|
-
}
|
|
122
|
-
}
|
|
123
|
-
this.hcTermNameOrder = this.settings.hierCluster.sortClusterRows == "asListed" ? twlst.map((t) => t.term.name) : this.settings.hierCluster.sortClusterRows == "byName" ? twlst.map((t) => t.term.name).sort() : dictionaryNumericTypes.has(this.config.dataType) ? c.row.order.map((row) => twlst.find((t) => t.$id == row.name || t.term.id == row.name)?.term.name) : c.row.order.map((row) => twlst.find((t) => t.$id == row.name)?.term.name);
|
|
124
|
-
if (this.hcTermNameOrder.includes(void 0)) throw `unable to map row.name to term.name`;
|
|
125
|
-
this.hcTermSorter = (a, b) => {
|
|
126
|
-
const i = this.hcTermNameOrder.indexOf(a.tw.term.name);
|
|
127
|
-
const j = this.hcTermNameOrder.indexOf(b.tw.term.name);
|
|
128
|
-
if (i == -1 && j == -1) return 0;
|
|
129
|
-
if (i == -1) return 1;
|
|
130
|
-
if (j == -1) return -1;
|
|
131
|
-
return i - j;
|
|
132
|
-
};
|
|
133
|
-
this.hcSampleNameOrder = c.col.order.map((col) => col.name);
|
|
134
|
-
this.hcSampleSorter = (a, b) => {
|
|
135
|
-
const i = this.hcSampleNameOrder.indexOf(a.sample);
|
|
136
|
-
const j = this.hcSampleNameOrder.indexOf(b.sample);
|
|
137
|
-
if (i == -1 && j == -1) return 0;
|
|
138
|
-
if (i == -1) return 1;
|
|
139
|
-
if (j == -1) return -1;
|
|
140
|
-
return i - j;
|
|
141
|
-
};
|
|
142
|
-
const byTermId = {};
|
|
143
|
-
for (const tw of twlst) {
|
|
144
|
-
if (d.byTermId?.[tw.term.name]) byTermId[tw.$id] = d.byTermId[tw.term.name];
|
|
145
|
-
}
|
|
146
|
-
this.hierClusterSamples = {
|
|
147
|
-
refs: { byTermId, bySampleId: d.bySampleId },
|
|
148
|
-
lst: c.col.order.map((c2) => samples[c2.name]),
|
|
149
|
-
samples,
|
|
150
|
-
removedHierClusterTerms: d.removedHierClusterTerms
|
|
151
|
-
};
|
|
152
|
-
}
|
|
153
|
-
async requestData() {
|
|
154
|
-
const body = this.currRequestOpts?.hierCluster || this.getHCRequestBody(this.state);
|
|
155
|
-
const twlst = this.hcTermGroup.lst;
|
|
156
|
-
const data = await dofetch3("termdb/cluster", { body, signal: this.api.getAbortSignal?.() });
|
|
157
|
-
return [data, twlst];
|
|
158
|
-
}
|
|
159
|
-
getHCRequestBody(state) {
|
|
160
|
-
this.hcTermGroup = this.config.termgroups.find((grp) => grp.type == "hierCluster") || this.termOrder?.find((t) => t.grp.type == "hierCluster")?.grp;
|
|
161
|
-
const s = state.config.settings.hierCluster;
|
|
162
|
-
const dictionaryLegendFilter = {
|
|
163
|
-
type: "tvslst",
|
|
164
|
-
in: true,
|
|
165
|
-
join: "and",
|
|
166
|
-
lst: state.config.legendValueFilter.lst.filter((f) => !f.tvs.legendFilterType)
|
|
167
|
-
};
|
|
168
|
-
const terms = this.getClusterRowTermsAsParameter();
|
|
169
|
-
if (!terms.length) throw "no data";
|
|
170
|
-
if (!clusterMethodLst.find((i) => i.value == s.clusterMethod)) throw "Invalid cluster method";
|
|
171
|
-
if (!distanceMethodLst.find((i) => i.value == s.distanceMethod)) throw "Invalid distance method";
|
|
172
|
-
const body = {
|
|
173
|
-
genome: state.vocab.genome,
|
|
174
|
-
dslabel: state.vocab.dslabel,
|
|
175
|
-
dataType: state.config.dataType,
|
|
176
|
-
clusterMethod: s.clusterMethod,
|
|
177
|
-
distanceMethod: s.distanceMethod,
|
|
178
|
-
zScoreTransformation: s.zScoreTransformation,
|
|
179
|
-
terms,
|
|
180
|
-
filter: getNormalRoot(filterJoin([state.filter, dictionaryLegendFilter])),
|
|
181
|
-
filter0: state.filter0
|
|
182
|
-
};
|
|
183
|
-
if (state.config.dataType == "proteomeAbundance") {
|
|
184
|
-
body.proteomeDetails = {
|
|
185
|
-
organism: state.config.proteomeDetails?.organism,
|
|
186
|
-
assay: state.config.proteomeDetails?.assay,
|
|
187
|
-
cohort: state.config.proteomeDetails?.cohort
|
|
188
|
-
};
|
|
189
|
-
}
|
|
190
|
-
return body;
|
|
191
|
-
}
|
|
192
|
-
combineData() {
|
|
193
|
-
if (!this.hierClusterSamples) return;
|
|
194
|
-
const d = this.data;
|
|
195
|
-
const removedHierClusterTerms = this.hierClusterSamples.removedHierClusterTerms;
|
|
196
|
-
const samples = {};
|
|
197
|
-
const lst = [];
|
|
198
|
-
for (const sampleId in this.hierClusterSamples.samples) {
|
|
199
|
-
const s = this.hierClusterSamples.samples[sampleId];
|
|
200
|
-
samples[sampleId] = s;
|
|
201
|
-
lst.push(s);
|
|
202
|
-
if (sampleId in d.samples) Object.assign(s, d.samples[sampleId]);
|
|
203
|
-
const _ref_ = this.hierClusterSamples.refs.bySampleId[sampleId] || {};
|
|
204
|
-
if (!s._ref_) s._ref_ = _ref_;
|
|
205
|
-
else Object.assign(s._ref_, _ref_);
|
|
206
|
-
}
|
|
207
|
-
const t = this.hierClusterSamples.refs.byTermId;
|
|
208
|
-
for (const $id of Object.keys(t)) {
|
|
209
|
-
d.refs.byTermId[$id] = Object.assign({}, d.refs.byTermId[$id] || {}, t[$id]);
|
|
210
|
-
}
|
|
211
|
-
this.data = { samples, lst, refs: d.refs, removedHierClusterTerms };
|
|
212
|
-
}
|
|
213
|
-
setHierColorScale(c) {
|
|
214
|
-
const hc = this.settings.hierCluster;
|
|
215
|
-
const scale = linear(colorScaleMap[hc.colorScale].domain, colorScaleMap[hc.colorScale].range).clamp(true);
|
|
216
|
-
const globalMinMaxes = [];
|
|
217
|
-
for (const row of c.matrix) {
|
|
218
|
-
globalMinMaxes.push(...extent(row));
|
|
219
|
-
}
|
|
220
|
-
const absMax = Math.min(hc.zScoreCap, Math.max(...extent(globalMinMaxes).map(Math.abs)));
|
|
221
|
-
const [min, max] = hc.zScoreTransformation ? [-absMax, absMax] : [Math.min(...globalMinMaxes), Math.max(...globalMinMaxes)];
|
|
222
|
-
this.hierClusterValues = { scale, min, max };
|
|
223
|
-
}
|
|
224
|
-
getValueColor(value) {
|
|
225
|
-
const hc = this.settings.hierCluster;
|
|
226
|
-
if (hc.zScoreTransformation) {
|
|
227
|
-
const zScoreCap = this.settings.hierCluster.zScoreCap;
|
|
228
|
-
return this.hierClusterValues.scale((value - -zScoreCap) / (zScoreCap * 2));
|
|
229
|
-
} else {
|
|
230
|
-
return this.hierClusterValues.scale(value / this.hierClusterValues.max);
|
|
231
|
-
}
|
|
232
|
-
}
|
|
233
|
-
/* returns list of gene terms as request parameter, e.g. {gene,chr,start,stop}
|
|
234
|
-
request parameter only need term but not tw, as it will simply fetch continuous sample values on terms without transform
|
|
235
|
-
|
|
236
|
-
use of this function is unfortunate because:
|
|
237
|
-
the incomplete migration of {name} to {gene} for gene-based term
|
|
238
|
-
geneset edit ui is hardcoded to return {name}
|
|
239
|
-
existing plot states contain {name}
|
|
240
|
-
|
|
241
|
-
!!! migration instruction !!!
|
|
242
|
-
- term.name is for display only, if a term is gene-based, it has term.gene=str
|
|
243
|
-
- a geneVariant term can be based on a genomic range (and not a gene), in that case it won't have term.gene and cannot be used where gene is expected, e.g. gene-based clustering analysis
|
|
244
|
-
|
|
245
|
-
*/
|
|
246
|
-
getClusterRowTermsAsParameter() {
|
|
247
|
-
const lst = this.hcTermGroup.lst.map(this.opts.app.vocabApi.getTwMinCopy);
|
|
248
|
-
lst.sort((a, b) => a.term.name < b.term.name ? -1 : 1);
|
|
249
|
-
return lst;
|
|
250
|
-
}
|
|
251
|
-
};
|
|
252
|
-
for (const methods of [hierCluster_renderers_exports, hierCluster_interactivity_exports]) {
|
|
253
|
-
for (const methodName in methods) HierCluster.prototype[methodName] = methods[methodName];
|
|
254
|
-
}
|
|
255
|
-
var hierClusterInit = getCompInit(HierCluster);
|
|
256
|
-
var componentInit = hierClusterInit;
|
|
257
|
-
|
|
258
|
-
export {
|
|
259
|
-
HierCluster,
|
|
260
|
-
hierClusterInit,
|
|
261
|
-
componentInit
|
|
262
|
-
};
|
|
263
|
-
//# sourceMappingURL=chunk-XCJHO2PZ.js.map
|
package/dist/chunk-XVBFTP6A.js
DELETED
|
@@ -1,294 +0,0 @@
|
|
|
1
|
-
import {
|
|
2
|
-
getSortOptions
|
|
3
|
-
} from "./chunk-D4UCM6R7.js";
|
|
4
|
-
import {
|
|
5
|
-
defaultUiLabels,
|
|
6
|
-
fillTermWrapper
|
|
7
|
-
} from "./chunk-FIFNXVTS.js";
|
|
8
|
-
import {
|
|
9
|
-
isDictionaryType
|
|
10
|
-
} from "./chunk-DBOJ3TMI.js";
|
|
11
|
-
import {
|
|
12
|
-
CNVClasses,
|
|
13
|
-
dtcnv,
|
|
14
|
-
mclass,
|
|
15
|
-
mutationClasses,
|
|
16
|
-
proteinChangingMutations,
|
|
17
|
-
synonymousMutations,
|
|
18
|
-
truncatingMutations
|
|
19
|
-
} from "./chunk-EZFO5UYD.js";
|
|
20
|
-
import {
|
|
21
|
-
copyMerge
|
|
22
|
-
} from "./chunk-HBNB5TRH.js";
|
|
23
|
-
|
|
24
|
-
// plots/matrix/matrix.config.js
|
|
25
|
-
async function getPlotConfig(opts = {}, app) {
|
|
26
|
-
const controlLabels = structuredClone(defaultUiLabels);
|
|
27
|
-
const devicePixelRatio = opts.devicePixelRatio || window.devicePixelRatio;
|
|
28
|
-
const config = {
|
|
29
|
-
// data configuration
|
|
30
|
-
termgroups: [],
|
|
31
|
-
samplegroups: [],
|
|
32
|
-
divideBy: null,
|
|
33
|
-
legendValueFilter: {
|
|
34
|
-
isAtomic: true,
|
|
35
|
-
type: "tvslst",
|
|
36
|
-
in: true,
|
|
37
|
-
join: "and",
|
|
38
|
-
lst: []
|
|
39
|
-
},
|
|
40
|
-
legendGrpFilter: {
|
|
41
|
-
isAtomic: true,
|
|
42
|
-
type: "tvslst",
|
|
43
|
-
in: true,
|
|
44
|
-
join: "and",
|
|
45
|
-
lst: []
|
|
46
|
-
},
|
|
47
|
-
filter: {
|
|
48
|
-
isAtomic: true,
|
|
49
|
-
type: "tvslst",
|
|
50
|
-
in: true,
|
|
51
|
-
join: "and",
|
|
52
|
-
lst: []
|
|
53
|
-
},
|
|
54
|
-
// cnvCutoffs: {},
|
|
55
|
-
// rendering options
|
|
56
|
-
settings: {
|
|
57
|
-
matrix: {
|
|
58
|
-
svgCanvasSwitch: 1e3,
|
|
59
|
-
// the number of samples to trigger switching between svg and canvas
|
|
60
|
-
useMinPixelWidth: true,
|
|
61
|
-
// canvas may be hazy if false, but more accurately reflects column density
|
|
62
|
-
cellEncoding: "",
|
|
63
|
-
// can be "oncoprint" | "stacked" | "single"
|
|
64
|
-
margin: {
|
|
65
|
-
top: 10,
|
|
66
|
-
right: 5,
|
|
67
|
-
bottom: 20,
|
|
68
|
-
left: 50
|
|
69
|
-
},
|
|
70
|
-
// set any dataset-defined sample limits and sort priority, otherwise undefined
|
|
71
|
-
// put in settings, so that later may be overridden by a user
|
|
72
|
-
maxGenes: opts.settings?.maxGenes || 50,
|
|
73
|
-
maxSample: opts.settings?.maxSample || 1e3,
|
|
74
|
-
sampleNameFilter: "",
|
|
75
|
-
sortSamplesBy: "a",
|
|
76
|
-
sortPriority: void 0,
|
|
77
|
-
// will be filled-in
|
|
78
|
-
sortBySampleAncestry: app.vocabApi.termdbConfig.hasSampleAncestry ? "last" : false,
|
|
79
|
-
// indicates sorting priority by sample ancestry
|
|
80
|
-
// sortByMutation: 'consequence', computed
|
|
81
|
-
// sortByCNV: true, computed
|
|
82
|
-
//sortOptions: getSortOptions(app.vocabApi.termdbConfig, controlLabels),
|
|
83
|
-
sortSampleGrpsBy: "name",
|
|
84
|
-
// 'hits' | 'name' | 'sampleCount'
|
|
85
|
-
sortSamplesTieBreakers: [{
|
|
86
|
-
$id: "sample",
|
|
87
|
-
sortSamples: {}
|
|
88
|
-
/*split: {char: '', index: 0}*/
|
|
89
|
-
}],
|
|
90
|
-
sortTermsBy: "sampleCount",
|
|
91
|
-
// or 'as listed'
|
|
92
|
-
// do not show number of samples at hiercluster gene row labels
|
|
93
|
-
samplecount4gene: opts.chartType == "hierCluster" ? "" : "abs",
|
|
94
|
-
//true, // 'abs' (default, previously true), 'pct', '' (previously false)
|
|
95
|
-
geneVariantCountSamplesSkipMclass: [],
|
|
96
|
-
cellbg: "#ececec",
|
|
97
|
-
showGrid: "",
|
|
98
|
-
// false | 'pattern' | 'rect'
|
|
99
|
-
// whether to show these controls buttons
|
|
100
|
-
addMutationCNVButtons: false,
|
|
101
|
-
truncatingMutations,
|
|
102
|
-
proteinChangingMutations,
|
|
103
|
-
synonymousMutations,
|
|
104
|
-
mutationClasses,
|
|
105
|
-
CNVClasses,
|
|
106
|
-
gridStroke: "#fff",
|
|
107
|
-
outlineStroke: "#ccc",
|
|
108
|
-
beamStroke: "#f00",
|
|
109
|
-
colw: 0,
|
|
110
|
-
colwMin: 0.1 / devicePixelRatio,
|
|
111
|
-
colwMax: 16,
|
|
112
|
-
colspace: 1,
|
|
113
|
-
colgspace: 8,
|
|
114
|
-
colglabelpos: true,
|
|
115
|
-
collabelpos: "bottom",
|
|
116
|
-
collabelvisible: true,
|
|
117
|
-
collabelgap: 5,
|
|
118
|
-
collabelpad: 1,
|
|
119
|
-
collabelmaxchars: 32,
|
|
120
|
-
rowh: 18,
|
|
121
|
-
//use 0 to auto-compute row height, previous default=18,
|
|
122
|
-
rowhMin: 1,
|
|
123
|
-
rowhMax: 20,
|
|
124
|
-
rowspace: 1,
|
|
125
|
-
rowgspace: 8,
|
|
126
|
-
rowlabelpos: "left",
|
|
127
|
-
// | 'right'
|
|
128
|
-
rowlabelgap: 5,
|
|
129
|
-
rowlabelvisible: true,
|
|
130
|
-
rowlabelpad: 1,
|
|
131
|
-
rowlabelmaxchars: 32,
|
|
132
|
-
legendGrpLabelMaxChars: 26,
|
|
133
|
-
grpLabelFontSize: 12,
|
|
134
|
-
minLabelFontSize: 6,
|
|
135
|
-
maxLabelFontSize: 14,
|
|
136
|
-
transpose: false,
|
|
137
|
-
// 'auto' shows column labels only when columns are wide enough (colw >= minLabelFontSize);
|
|
138
|
-
sampleLabelsToggle: "auto",
|
|
139
|
-
// 'auto' | 'hide'
|
|
140
|
-
sampleLabelOffset: 120,
|
|
141
|
-
sampleGrpLabelOffset: 120,
|
|
142
|
-
sampleGrpLabelMaxChars: 32,
|
|
143
|
-
termLabelOffset: 80,
|
|
144
|
-
termGrpLabelOffset: 80,
|
|
145
|
-
termGrpLabelMaxChars: 32,
|
|
146
|
-
duration: 0,
|
|
147
|
-
zoomLevel: 1,
|
|
148
|
-
zoomCenterPct: 0,
|
|
149
|
-
zoomIndex: 0,
|
|
150
|
-
zoomGrpIndex: 0,
|
|
151
|
-
zoomMin: 0.5,
|
|
152
|
-
zoomIncrement: 0.1,
|
|
153
|
-
zoomStep: 1,
|
|
154
|
-
// renderedWMax should not be exposed as a user-input
|
|
155
|
-
// 60000 pixels is based on laptop and external monitor tests,
|
|
156
|
-
// when a canvas dataURL image in a zoomed-in matrix svg stops rendering
|
|
157
|
-
imgWMax: 6e4 / devicePixelRatio,
|
|
158
|
-
scrollHeight: 12,
|
|
159
|
-
controlLabels,
|
|
160
|
-
cnvUnit: "log2ratio",
|
|
161
|
-
ignoreCnvValues: false,
|
|
162
|
-
//will ignore numeric CNV values if true
|
|
163
|
-
barh: 32,
|
|
164
|
-
// default bar height for continuous terms,
|
|
165
|
-
// possible string entries:
|
|
166
|
-
// - "genesetEdit", for gene-centric embedders only like GDC OncoMatrix
|
|
167
|
-
// - may add other optional hints later
|
|
168
|
-
showHints: [],
|
|
169
|
-
genesetEditUiVersion: "",
|
|
170
|
-
// '' | 'withTabs'
|
|
171
|
-
// settings for a specific tw
|
|
172
|
-
twSpecificSettings: {},
|
|
173
|
-
oncoPrintSNVindelCellBorder: false,
|
|
174
|
-
// whether to show white cell border for SNVindel in oncoPrint mode
|
|
175
|
-
cnvValues: {
|
|
176
|
-
//Properties match the args for the ColorScales
|
|
177
|
-
//numericInput arg
|
|
178
|
-
cutoffMode: "percentile",
|
|
179
|
-
defaultPercentile: 99,
|
|
180
|
-
min: null,
|
|
181
|
-
max: null,
|
|
182
|
-
percentile: 99
|
|
183
|
-
}
|
|
184
|
-
}
|
|
185
|
-
}
|
|
186
|
-
};
|
|
187
|
-
const s = config.settings;
|
|
188
|
-
const fontsize = Math.max(s.matrix.rowh + s.matrix.rowspace - 3 * s.matrix.rowlabelpad, 12);
|
|
189
|
-
s.legend = {
|
|
190
|
-
ontop: false,
|
|
191
|
-
lineh: 25,
|
|
192
|
-
padx: 5,
|
|
193
|
-
padleft: 0,
|
|
194
|
-
//150,
|
|
195
|
-
padright: 20,
|
|
196
|
-
padbtm: 30,
|
|
197
|
-
fontsize,
|
|
198
|
-
iconh: fontsize - 2,
|
|
199
|
-
iconw: fontsize - 2,
|
|
200
|
-
hangleft: 1,
|
|
201
|
-
linesep: false
|
|
202
|
-
};
|
|
203
|
-
const overrides = app.vocabApi.termdbConfig.matrix || {};
|
|
204
|
-
copyMerge(config.settings.matrix, overrides.settings);
|
|
205
|
-
if (overrides.legendGrpFilter) config.legendGrpFilter = overrides.legendGrpFilter;
|
|
206
|
-
if (overrides.legendValueFilter) config.legendValueFilter = overrides.legendValueFilter;
|
|
207
|
-
if (overrides.filter) config.filter = overrides.filter;
|
|
208
|
-
if (opts.name) {
|
|
209
|
-
const data = await app.vocabApi.getMatrixByName(opts.name);
|
|
210
|
-
if (!data) throw "error from getMatrixByName()";
|
|
211
|
-
if (data.error) throw data.error;
|
|
212
|
-
copyMerge(config, data);
|
|
213
|
-
}
|
|
214
|
-
const os = opts?.settings?.matrix;
|
|
215
|
-
if (os) {
|
|
216
|
-
if ((os.sortSamplesBy == "custom" || os.sortSamplesBy == "asListed") && os.sortOptions?.custom.label == "against alteration type") {
|
|
217
|
-
os.sortSamplesBy = "a";
|
|
218
|
-
}
|
|
219
|
-
if (os.sortOptions) {
|
|
220
|
-
delete os.sortOptions.custom;
|
|
221
|
-
delete os.sortOptions.asListed;
|
|
222
|
-
}
|
|
223
|
-
}
|
|
224
|
-
copyMerge(config, opts);
|
|
225
|
-
const m = config.settings.matrix;
|
|
226
|
-
m.sortOptions = getSortOptions(app.vocabApi.termdbConfig, controlLabels, m);
|
|
227
|
-
m.duration = 0;
|
|
228
|
-
m.colw = 0;
|
|
229
|
-
if (m.sortSamplesBy != "asListed" && !m.sortOptions?.[m.sortSamplesBy]) m.sortSamplesBy = "a";
|
|
230
|
-
else if (["selectedTerms", "class", "dt", "hits"].includes(m.sortSamplesBy)) m.sortSamplesBy = "a";
|
|
231
|
-
if (m.samplecount4gene === true || m.samplecount4gene === 1) m.samplecount4gene = "abs";
|
|
232
|
-
if (window.location.hostname == "localhost") {
|
|
233
|
-
if (window.location.hash == "#canvas") m.svgCanvasSwitch = 0;
|
|
234
|
-
}
|
|
235
|
-
for (const grp of config.termgroups) {
|
|
236
|
-
const promises = [];
|
|
237
|
-
for (const tw of grp.lst) {
|
|
238
|
-
if (!tw.term?.type || isDictionaryType(tw.term.type)) {
|
|
239
|
-
if (!tw.id && tw.term.type != "samplelst" && tw.term.type != "termCollection") {
|
|
240
|
-
if (!tw.term.id) throw `missing tw.id and tw.term.id`;
|
|
241
|
-
tw.id = tw.term.id;
|
|
242
|
-
}
|
|
243
|
-
if (tw.term?.type != "samplelst" && tw.term?.type != "termCollection") delete tw.term;
|
|
244
|
-
}
|
|
245
|
-
promises.push(fillTermWrapper(tw, app.vocabApi));
|
|
246
|
-
}
|
|
247
|
-
grp.lst = await Promise.all(promises);
|
|
248
|
-
}
|
|
249
|
-
if (config.divideBy) config.divideBy = await fillTermWrapper(config.divideBy, app.vocabApi);
|
|
250
|
-
return config;
|
|
251
|
-
}
|
|
252
|
-
function setComputedConfig(config) {
|
|
253
|
-
const s = config.settings.matrix;
|
|
254
|
-
const allClasses = [...s.mutationClasses, ...s.CNVClasses];
|
|
255
|
-
s.filterByClass = { isAtomic: true };
|
|
256
|
-
for (const f of config.legendGrpFilter.lst) {
|
|
257
|
-
if (!f.dt) continue;
|
|
258
|
-
allClasses.filter((m) => f.dt.includes(mclass[m].dt)).forEach((key2) => {
|
|
259
|
-
s.filterByClass[key2] = "value";
|
|
260
|
-
});
|
|
261
|
-
}
|
|
262
|
-
for (const f of config.legendValueFilter.lst) {
|
|
263
|
-
if (!f.legendGrpName || f.tvs?.term?.type !== "geneVariant") continue;
|
|
264
|
-
if (f.tvs.values?.[0].mclasslst)
|
|
265
|
-
f.tvs.values[0].mclasslst.forEach((key2) => {
|
|
266
|
-
s.filterByClass[key2] = f.legendFilterType?.endsWith("_hard") ? "case" : "value";
|
|
267
|
-
});
|
|
268
|
-
else if (f.tvs.values)
|
|
269
|
-
f.tvs.values.forEach((v) => {
|
|
270
|
-
s.filterByClass[key] = "value";
|
|
271
|
-
});
|
|
272
|
-
else throw `unhandled tvs from legendValueFilter`;
|
|
273
|
-
}
|
|
274
|
-
s.hiddenVariants = Object.keys(s.filterByClass).filter((c) => c !== "isAtomic");
|
|
275
|
-
const hiddenCNVs = new Set(s.hiddenVariants.filter((key2) => mclass[key2]?.dt === dtcnv));
|
|
276
|
-
s.hiddenCNVs = [...hiddenCNVs];
|
|
277
|
-
s.showMatrixCNV = !hiddenCNVs.size ? "all" : hiddenCNVs.size == s.CNVClasses.length ? "none" : "bySelection";
|
|
278
|
-
s.allMatrixCNVHidden = hiddenCNVs.size == s.CNVClasses.length;
|
|
279
|
-
const hiddenMutations = new Set(s.hiddenVariants.filter((key2) => s.mutationClasses.find((k) => k === key2)));
|
|
280
|
-
s.hiddenMutations = [...hiddenMutations];
|
|
281
|
-
const PCset = new Set(s.proteinChangingMutations);
|
|
282
|
-
const TMset = new Set(s.truncatingMutations);
|
|
283
|
-
s.showMatrixMutation = !hiddenMutations.size ? "all" : hiddenMutations.size == s.mutationClasses.length ? "none" : hiddenMutations.size === s.mutationClasses.length - PCset.size && [...hiddenMutations].every((m) => !PCset.has(m)) ? "onlyPC" : hiddenMutations.size === s.mutationClasses.length - TMset.size && [...hiddenMutations].every((m) => !TMset.has(m)) ? "onlyTruncating" : "bySelection";
|
|
284
|
-
s.allMatrixMutationHidden = hiddenMutations.size == s.mutationClasses.length;
|
|
285
|
-
const tiebreakers = s.sortOptions.a?.sortPriority.find((sp) => sp.types.length == 1 && sp.types[0] == "geneVariant")?.tiebreakers || [];
|
|
286
|
-
s.sortByMutation = tiebreakers.find((tb) => tb.filter?.values[0]?.dt === 1)?.isOrdered ? "consequence" : "presence";
|
|
287
|
-
s.sortByCNV = tiebreakers.find((tb) => tb.filter?.values[0]?.dt === 4)?.disabled !== true;
|
|
288
|
-
}
|
|
289
|
-
|
|
290
|
-
export {
|
|
291
|
-
getPlotConfig,
|
|
292
|
-
setComputedConfig
|
|
293
|
-
};
|
|
294
|
-
//# sourceMappingURL=chunk-XVBFTP6A.js.map
|