@sjcrh/proteinpaint-client 2.210.1 → 2.211.0
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/2dmaf-FEZRNHDF.js +1367 -0
- package/dist/AggMatrixInput-6FJIELYO.js +406 -0
- package/dist/AggregateMatrix-MUPBUGIZ.js +41 -0
- package/dist/AppHeader-ZTNZ62UL.js +830 -0
- package/dist/BoxPlot-P5SVFYSB.js +1208 -0
- package/dist/BoxPlot-P5SVFYSB.js.map +7 -0
- package/dist/CorrelationVolcano-42NYXAXG.js +617 -0
- package/dist/Cuminc-6AKLT6HF.js +1219 -0
- package/dist/DE-KJHFZWND.js +89 -0
- package/dist/DEinput-HXB3LYZW.js +501 -0
- package/dist/DM-AAHX4PLH.js +90 -0
- package/dist/DifferentialAnalysis-JX4EDEOY.js +239 -0
- package/dist/Disco-GXKO4QQH.js +3389 -0
- package/dist/Disco.UI-DGD4RXJP.js +243 -0
- package/dist/DmrPlot-DQ3XTMTN.js +362 -0
- package/dist/GB-OUWNNBBK.js +1392 -0
- package/dist/GSEA-DSKGFAPG.js +875 -0
- package/dist/GeneExpInput-FZLOBE2Q.js +42 -0
- package/dist/Geomap-GP5KD3OX.js +84 -0
- package/dist/HicApp-2N6WYWZX.js +2245 -0
- package/dist/IDCViewer-MSUC7IXX.js +10812 -0
- package/dist/NumBinaryEditor-C4G2IH36.js +279 -0
- package/dist/NumBinaryEditor.unit.spec-ZAVAUGXA.js +312 -0
- package/dist/NumContEditor-VEEMMWHX.js +105 -0
- package/dist/NumContEditor.unit.spec-65ORC42O.js +164 -0
- package/dist/NumCustomBinEditor-YIUHJAXP.js +33 -0
- package/dist/NumCustomBinEditor.unit.spec-NT5VK2LO.js +397 -0
- package/dist/NumDiscreteEditor-A4WELAJH.js +170 -0
- package/dist/NumDiscreteEditor.unit.spec-7QABM6KK.js +233 -0
- package/dist/NumRegularBinEditor-IPVPLSQY.js +33 -0
- package/dist/NumRegularBinEditor.unit.spec-Q4DMWATB.js +278 -0
- package/dist/NumSplineEditor-5E6CIWLP.js +210 -0
- package/dist/NumSplineEditor.unit.spec-DHJF5F6H.js +224 -0
- package/dist/NumericDensity-GXMWWK2A.js +33 -0
- package/dist/NumericDensity.unit.spec-OAPOMSEW.js +418 -0
- package/dist/NumericHandler-H5WHGFXD.js +34 -0
- package/dist/NumericHandler.unit.spec-PBNOJEMS.js +214 -0
- package/dist/ProteomeInput-ZA7R5S43.js +388 -0
- package/dist/Regression-WSWTSXFX.js +1416 -0
- package/dist/RunChart2-J5CTJI5C.js +749 -0
- package/dist/SC-POCQDMWZ.js +1181 -0
- package/dist/SC-POCQDMWZ.js.map +7 -0
- package/dist/Violin-VA6FBRUQ.js +1064 -0
- package/dist/Violin-VA6FBRUQ.js.map +7 -0
- package/dist/Volcano-4IEQIEDS.js +2456 -0
- package/dist/Wsi-LJ6AY5RI.js +629 -0
- package/dist/adSandbox-EIN4KEML.js +33 -0
- package/dist/animatedBubbleChart-LINYUKMD.js +547 -0
- package/dist/app-SE7UQ5DB.js +42 -0
- package/dist/app-VGMZNGWP.js +32 -0
- package/dist/app.js +16 -16
- package/dist/bam-ZXEZWRSZ.js +876 -0
- package/dist/barchart-N4B4C2FO.js +42 -0
- package/dist/barchart2-EDVEWTVX.js +309 -0
- package/dist/block-E7YUGCHL.js +6250 -0
- package/dist/block.init-FSOCF2IM.js +33 -0
- package/dist/block.mds.expressionrank-EDBTITXU.js +354 -0
- package/dist/block.mds.geneboxplot-GG5672SY.js +823 -0
- package/dist/block.mds.junction-HUC4S24K.js +1539 -0
- package/dist/block.mds.svcnv-EQHYCIBU.js +6796 -0
- package/dist/block.svg-HBVPUQJ2.js +159 -0
- package/dist/block.tk.aicheck-TRJ5IIWZ.js +278 -0
- package/dist/block.tk.ase-COV7YYYO.js +360 -0
- package/dist/block.tk.bam-MDSLY6NH.js +1901 -0
- package/dist/block.tk.bedgraphdot-MKWEL53X.js +379 -0
- package/dist/block.tk.bigwig.ui-UKKJX7TA.js +206 -0
- package/dist/block.tk.hicstraw-6LNXEIOF.js +818 -0
- package/dist/block.tk.junction-F3SERFFD.js +2358 -0
- package/dist/block.tk.junction.textmatrixui-2XUMSKLS.js +194 -0
- package/dist/block.tk.ld-COP5RUJJ.js +94 -0
- package/dist/block.tk.menu-SRDPD44N.js +1024 -0
- package/dist/block.tk.pgv-3SVINTXN.js +938 -0
- package/dist/brainImaging-UNBA4KA3.js +555 -0
- package/dist/brainRegions-DC6TQB53.js +217 -0
- package/dist/bubbleHeatmap-X3W3AZJY.js +378 -0
- package/dist/cellTypeBubbleHeatmap-LFI6TGOO.js +278 -0
- package/dist/chunk-2ANFUNS3.js +102 -0
- package/dist/chunk-2G4SFRWC.js +1278 -0
- package/dist/chunk-2WKGE7BO.js +54 -0
- package/dist/chunk-3CGMCYZB.js +237 -0
- package/dist/chunk-3I4DBVLM.js +55 -0
- package/dist/chunk-42VFF74T.js +397 -0
- package/dist/chunk-4ENIOXIT.js +133 -0
- package/dist/chunk-4ENIOXIT.js.map +7 -0
- package/dist/chunk-4HTRCXLS.js +98 -0
- package/dist/chunk-55T2AMJ3.js +281 -0
- package/dist/chunk-57Z4VYLM.js +1616 -0
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- package/dist/chunk-GP4VLNMZ.js.map +7 -0
- package/dist/chunk-HTZJQNHP.js +562 -0
- package/dist/chunk-ITYNHDDD.js +56 -0
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- package/dist/chunk-J4WRX5G6.js +263 -0
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- package/dist/chunk-K7HFOAR7.js +25008 -0
- package/dist/chunk-K7HFOAR7.js.map +7 -0
- package/dist/chunk-KJGYGPJZ.js +103 -0
- package/dist/chunk-L3UFI52T.js +217 -0
- package/dist/chunk-L4ZPMF7E.js +692 -0
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- package/dist/chunk-MVWJHZ5G.js +783 -0
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- package/dist/chunk-VSTHBKQW.js +480 -0
- package/dist/chunk-W7A4QXZ7.js +38 -0
- package/dist/chunk-WKCVZIN7.js +59 -0
- package/dist/chunk-X7TJBXJJ.js +54 -0
- package/dist/chunk-XEEMCYP6.js +4375 -0
- package/dist/chunk-XTQWAVWJ.js +54 -0
- package/dist/chunk-YAN2MOON.js +5071 -0
- package/dist/chunk-YCBENC6R.js +1769 -0
- package/dist/chunk-YCBENC6R.js.map +7 -0
- package/dist/chunk-YCORHJ64.js +240 -0
- package/dist/chunk-YOBTHZVU.js +80 -0
- package/dist/chunk-ZTT6ZHU5.js +217 -0
- package/dist/cohort-RF4FT2NT.js +70 -0
- package/dist/condition-WXE2CFYT.js +327 -0
- package/dist/controls-AYF4H7UG.js +34 -0
- package/dist/controls.config-TXZKQNYC.js +34 -0
- package/dist/correlation-UAYMVVUS.js +95 -0
- package/dist/customdata.inputui-I7RFOGYM.js +284 -0
- package/dist/dataDownload-4AGSDSEO.js +329 -0
- package/dist/databrowser.ui-RGJEA2BI.js +425 -0
- package/dist/dictionary-AWWQXIRP.js +113 -0
- package/dist/dnaMethylation-PICKZS2M.js +33 -0
- package/dist/dnaMethylation.integration.spec-JUSB3CFZ.js +198 -0
- package/dist/dofetch-ZJMKEYN2.js +48 -0
- package/dist/e2pca-K4W7ZJZG.js +344 -0
- package/dist/ep-OY5YQMEF.js +1249 -0
- package/dist/expclust.gdc.spec-LYDBM3TZ.js +302 -0
- package/dist/facet-7NJHLLCZ.js +519 -0
- package/dist/gb-COV44BMA.js +81 -0
- package/dist/geneExpClustering-EQR5XX4J.js +244 -0
- package/dist/geneExpression-2BNDQ6S6.js +310 -0
- package/dist/geneExpression-PGB6WF5H.js +33 -0
- package/dist/geneExpression.unit.spec-OUNGGOJP.js +128 -0
- package/dist/geneORA-EKNEVQOS.js +273 -0
- package/dist/geneRanking-XUXLRERA.js +548 -0
- package/dist/geneVariant-JZDYV6LS.js +36 -0
- package/dist/geneVariant-KPZ2FYLK.js +289 -0
- package/dist/geneVariant.integration.spec-ISMLGTKC.js +503 -0
- package/dist/genefusion.ui-GRUXFC4U.js +303 -0
- package/dist/geneset-RM4XIX23.js +203 -0
- package/dist/genomeBrowser.spec-X7EOK2LS.js +276 -0
- package/dist/grin2-5XRUMYQO.js +949 -0
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- package/dist/hierCluster-I6T4XD3P.js +55 -0
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- package/dist/hierCluster.interactivity-B5ZNFF4R.js +49 -0
- package/dist/hierCluster.renderers-R2DTKTLI.js +19 -0
- package/dist/imagePlot-ZM4IVDJT.js +156 -0
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- package/dist/isoformExpression-BFCLGD2U.js +35 -0
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- package/dist/launch.adhoc-AHTCA2BP.js +37 -0
- package/dist/leftlabel.sample-LIBMKP22.js +258 -0
- package/dist/lollipop-26ZQH3EL.js +166 -0
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import {
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make_radios
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} from "./chunk-K7HFOAR7.js";
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import {
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initBinConfig
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} from "./chunk-GP4VLNMZ.js";
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import {
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toStoredUnit,
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toUserUnit
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} from "./chunk-W5J3LTYS.js";
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import {
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format
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} from "./chunk-4OLM3KSB.js";
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// termsetting/handlers/NumRegularBinEditor.ts
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var NumRegularBinEditor = class {
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constructor(editHandler) {
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this.dom = {};
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this.editHandler = editHandler;
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this.opts = editHandler.opts;
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this.tw = editHandler.tw;
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this.termsetting = editHandler.termsetting;
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}
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/* q holds bin boundaries in the unit the term's values are stored in, while the <input>s and the
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density plot show them in the term's user-facing unit. toDisplay()/toStored() cross that boundary;
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both are identity functions unless the term declares valueConversion{} */
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toDisplay(v) {
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return toUserUnit(v, this.tw.term);
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}
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toStored(v) {
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return toStoredUnit(v, this.tw.term);
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}
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render(div) {
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this.tw = this.editHandler.tw;
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const isRemounting = !!this.dom.binsTable && this.editHandler.dom.binsDiv?.node().contains(this.dom.binsTable.node());
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if (!isRemounting) this.q = this.getDefaultQ();
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this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
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if (isRemounting) return;
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if (this.dom.binsTable) {
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this.dom.binsTable.remove();
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delete this.dom.binsTable;
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}
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const binsTable = div.append("table");
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this.dom.binsTable = binsTable;
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this.renderBinSizeInput(binsTable.append("tr"));
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this.renderFirstBinInput(binsTable.append("tr"));
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this.renderLastBinInputs(binsTable.append("tr"));
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}
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getDefaultQ() {
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if (this.tw.q.type == "regular-bin") return JSON.parse(JSON.stringify(this.tw.q));
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const t = this.tw.term;
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const defaultQ = this.termsetting.opts.use_bins_less && t.bins?.less || t.bins?.default;
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if (defaultQ) return JSON.parse(JSON.stringify(defaultQ));
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const binConfig = initBinConfig(this.editHandler.handler.density_data);
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return typeof binConfig == "string" ? JSON.parse(binConfig) : binConfig;
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}
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renderBinSizeInput(tr) {
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const handler = this.editHandler.handler;
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tr.append("td").style("margin", "5px").style("opacity", 0.5).text("Bin Size");
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const { min, max } = handler.density_data;
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const q = this.q;
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const origBinSize = this.toDisplay(q.bin_size);
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this.dom.bin_size_input = tr.append("td").append("input").attr("type", "number").attr(
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"value",
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handler.density.scaleFactor == 1 && "rounding" in q ? format(q.rounding || ".0f")(q.bin_size) : origBinSize
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).attr("data-testid", "sjpp-num-reg-bin-editor-size").style("margin-left", "15px").style("width", "100px").style("color", () => q.bin_size > Math.abs(max - min) ? "red" : "").on("change", (event) => {
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const newValue = this.toStored(Number(event.target.value));
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if (newValue <= 0) {
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window.alert("Please enter non-negative bin size.");
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event.target.value = origBinSize;
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return;
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}
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if ((max - min) / newValue > 100) {
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window.alert("Bin size too small. Try setting a bigger value.");
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event.target.value = origBinSize;
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return;
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}
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q.bin_size = newValue;
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this.dom.bin_size_input.style(
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"color",
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q.bin_size > max - min ? "red" : this.toDisplay(newValue) != origBinSize ? "green" : ""
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);
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handler.density.setBinLines(this.getBoundaryOpts());
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});
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}
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renderFirstBinInput(tr) {
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const handler = this.editHandler.handler;
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const q = this.q;
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if (!q.first_bin) throw "missing q.first_bin";
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tr.append("td").style("margin", "5px").style("opacity", 0.5).text("First Bin Stop");
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const { min, max } = handler.density_data;
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const origValue = this.toDisplay(q.first_bin.stop);
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this.dom.first_stop_input = tr.append("td").append("input").attr("type", "number").property("value", origValue).style("width", "100px").style("margin-left", "15px").on("change", (event) => {
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const newValue = this.toStored(Number(event.target.value));
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if (Number(event.target.value) < this.toDisplay(min) || Number(event.target.value) > this.toDisplay(max)) {
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window.alert("First bin stop value out of bound.");
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event.target.value = origValue;
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return;
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}
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this.q.first_bin.stop = newValue;
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handler.density.setBinLines(this.getBoundaryOpts());
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});
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tr.append("td").append("div").style("font-size", ".6em").style("opacity", 0.5).style("display", handler.density.no_density_data ? "none" : "block").text("Indicated by left-most red line. Drag to change.");
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}
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renderLastBinInputs(tr) {
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const handler = this.editHandler.handler;
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const q = this.q;
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const isAuto = !q.last_bin || !Number.isFinite(q.last_bin.start);
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tr.append("td").style("padding-top", "4px").style("opacity", 0.5).style("vertical-align", "top").text("Last Bin Start");
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const td1 = tr.append("td").style("padding-left", "15px").style("vertical-align", "top");
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const radio_div = td1.append("div");
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const radios = make_radios({
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holder: radio_div,
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options: [
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{ label: "Automatic", value: "auto", checked: isAuto },
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{ label: "Fixed", value: "fixed", checked: !isAuto }
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],
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callback: (v) => {
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if (v == "auto") {
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delete q.last_bin;
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edit_div.style("display", "none");
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handler.density.setBinLines(this.getBoundaryOpts());
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return;
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}
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125
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edit_div.style("display", "inline-block");
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if (this.dom.last_start_input.property("value") == "") {
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this.dom.last_start_input.property(
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"value",
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this.toDisplay(this.tw.q.last_bin?.start || handler.density_data.max)
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);
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}
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this.setLastBinStart();
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}
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});
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135
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this.dom.fixed_radio = radios.inputs.filter((_, i) => i === 1);
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const edit_div = tr.append("td").append("div").style("display", isAuto ? "none" : "inline-block");
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137
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this.dom.last_start_input = edit_div.append("input").attr("type", "number").property("value", Number.isFinite(q.last_bin?.start) ? this.toDisplay(q.last_bin.start) : "").style("width", "100px").on("change", () => this.setLastBinStart());
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138
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edit_div.append("div").style("font-size", ".6em").style("opacity", 0.5).style("display", handler.density.no_density_data ? "none" : "block").text("Indicated by right-most red line. Drag to change.");
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139
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}
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140
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setLastBinStart() {
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141
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const q = this.q;
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const { max } = this.editHandler.handler.density_data;
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143
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const strInput = this.dom.last_start_input.property("value");
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144
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if (strInput === "") return;
|
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145
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const inputValue = this.toStored(Number(strInput));
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|
146
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if (q.first_bin && Number(strInput) <= this.toDisplay(q.first_bin.stop)) {
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147
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window.alert("Last bin start cannot be smaller than first bin stop.");
|
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148
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+
this.dom.last_start_input.property("value", this.toDisplay(max));
|
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149
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return;
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150
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+
}
|
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151
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+
if (Number(strInput) > this.toDisplay(max)) {
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window.alert("Last bin start value out of bound.");
|
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153
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this.dom.last_start_input.property("value", this.toDisplay(max));
|
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154
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return;
|
|
155
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+
}
|
|
156
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+
if (q.last_bin) q.last_bin.start = inputValue;
|
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157
|
+
else
|
|
158
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q.last_bin = {
|
|
159
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+
start: inputValue,
|
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160
|
+
stopunbounded: true,
|
|
161
|
+
stopinclusive: false
|
|
162
|
+
};
|
|
163
|
+
this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
|
|
164
|
+
}
|
|
165
|
+
getBoundaryOpts() {
|
|
166
|
+
const { min, max } = this.editHandler.handler.density_data;
|
|
167
|
+
const binLinesStop = this.q.last_bin?.start ?? max + Math.abs(this.q.first_bin.stop) - Math.min(min, 0);
|
|
168
|
+
const boundaryValues = [];
|
|
169
|
+
for (let i = this.q.first_bin.stop; i <= binLinesStop; i = i + this.q.bin_size) {
|
|
170
|
+
if (this.q.last_bin?.start === i) break;
|
|
171
|
+
if (i > binLinesStop) boundaryValues[boundaryValues.length - 1].isLastVisibleLine = true;
|
|
172
|
+
const isDraggable = i === this.q.first_bin.stop || i === this.q.bin_size - 1;
|
|
173
|
+
boundaryValues.push({ x: this.toDisplay(i), isDraggable, movesWithLineIndex: !isDraggable ? 0 : -1 });
|
|
174
|
+
}
|
|
175
|
+
if (this.q.last_bin) {
|
|
176
|
+
boundaryValues.push({
|
|
177
|
+
x: this.toDisplay(this.q.last_bin.start),
|
|
178
|
+
isDraggable: true,
|
|
179
|
+
isLastVisibleLine: true,
|
|
180
|
+
movesWithLineIndex: -1
|
|
181
|
+
});
|
|
182
|
+
}
|
|
183
|
+
return {
|
|
184
|
+
values: boundaryValues,
|
|
185
|
+
// the dragged value arrives in display units, matching what the <input>s show
|
|
186
|
+
callback: (d, value) => {
|
|
187
|
+
if (d.index === 0) {
|
|
188
|
+
this.dom.first_stop_input.property("value", value);
|
|
189
|
+
this.q.first_bin.stop = this.toStored(value);
|
|
190
|
+
} else {
|
|
191
|
+
this.dom.last_start_input.property("value", value);
|
|
192
|
+
if (this.q.last_bin) this.q.last_bin.start = this.toStored(value);
|
|
193
|
+
}
|
|
194
|
+
}
|
|
195
|
+
};
|
|
196
|
+
}
|
|
197
|
+
getEditedQ(destroyDom = true) {
|
|
198
|
+
const bin_size = this.dom.bin_size_input.property("value");
|
|
199
|
+
const config = {
|
|
200
|
+
mode: "discrete",
|
|
201
|
+
type: "regular-bin",
|
|
202
|
+
startinclusive: this.editHandler.boundaryInclusion == "startinclusive",
|
|
203
|
+
stopinclusive: this.editHandler.boundaryInclusion == "stopinclusive",
|
|
204
|
+
bin_size: this.toStored(Number(bin_size)),
|
|
205
|
+
first_bin: {
|
|
206
|
+
startunbounded: true,
|
|
207
|
+
stop: this.toStored(Number(this.dom.first_stop_input.property("value")))
|
|
208
|
+
},
|
|
209
|
+
/* rounding formats the stored bin size, so it cannot be derived from the decimals of a
|
|
210
|
+
converted input. a converted term labels its bins through valueConversion instead */
|
|
211
|
+
rounding: this.editHandler.handler.density.scaleFactor != 1 ? ".0f" : bin_size.includes(".") && !bin_size.endsWith(".") ? `.${bin_size.split(".")[1].length}f` : ".0f"
|
|
212
|
+
};
|
|
213
|
+
if (this.dom.fixed_radio.property("checked")) {
|
|
214
|
+
config.last_bin = {
|
|
215
|
+
start: this.toStored(Number(this.dom.last_start_input.property("value"))),
|
|
216
|
+
stopunbounded: true
|
|
217
|
+
};
|
|
218
|
+
}
|
|
219
|
+
if (destroyDom) {
|
|
220
|
+
for (const name of Object.keys(this.dom)) {
|
|
221
|
+
this.dom[name].remove();
|
|
222
|
+
delete this.dom[name];
|
|
223
|
+
}
|
|
224
|
+
}
|
|
225
|
+
return config;
|
|
226
|
+
}
|
|
227
|
+
undoEdits() {
|
|
228
|
+
this.q = this.getDefaultQ();
|
|
229
|
+
this.dom.binsTable.selectAll("*").remove();
|
|
230
|
+
this.renderBinSizeInput(this.dom.binsTable.append("tr"));
|
|
231
|
+
this.renderFirstBinInput(this.dom.binsTable.append("tr"));
|
|
232
|
+
this.renderLastBinInputs(this.dom.binsTable.append("tr"));
|
|
233
|
+
this.editHandler.handler.density.setBinLines(this.getBoundaryOpts());
|
|
234
|
+
}
|
|
235
|
+
};
|
|
236
|
+
|
|
237
|
+
export {
|
|
238
|
+
NumRegularBinEditor
|
|
239
|
+
};
|
|
240
|
+
//# sourceMappingURL=chunk-YCORHJ64.js.map
|
|
@@ -0,0 +1,80 @@
|
|
|
1
|
+
import {
|
|
2
|
+
addGeneSearchbox,
|
|
3
|
+
getGEunit,
|
|
4
|
+
getSampleTypeLabelByTerms,
|
|
5
|
+
getSelectedSampleTypes,
|
|
6
|
+
getSelectedSampleTypesByTerms,
|
|
7
|
+
renderSampleTypeSelect,
|
|
8
|
+
renderSampleTypesByTermsSelect,
|
|
9
|
+
table2col
|
|
10
|
+
} from "./chunk-K7HFOAR7.js";
|
|
11
|
+
import {
|
|
12
|
+
Menu
|
|
13
|
+
} from "./chunk-7XZA2XR2.js";
|
|
14
|
+
import {
|
|
15
|
+
TermTypes
|
|
16
|
+
} from "./chunk-57Z4VYLM.js";
|
|
17
|
+
|
|
18
|
+
// termdb/handlers/geneExpression.ts
|
|
19
|
+
var SearchHandler = class {
|
|
20
|
+
init(opts) {
|
|
21
|
+
this.callback = opts.callback;
|
|
22
|
+
this.app = opts.app;
|
|
23
|
+
this.dom = {};
|
|
24
|
+
const holder = opts.holder.append("div").style("padding", "10px 0px");
|
|
25
|
+
this.dom.sampleTypeDiv = holder.append("div");
|
|
26
|
+
this.mayRenderSampleTypeSelect();
|
|
27
|
+
const geneSearch = addGeneSearchbox({
|
|
28
|
+
tip: new Menu({ padding: "0px" }),
|
|
29
|
+
genome: opts.genomeObj,
|
|
30
|
+
row: holder,
|
|
31
|
+
searchOnly: "gene",
|
|
32
|
+
callback: () => this.selectGene(geneSearch)
|
|
33
|
+
});
|
|
34
|
+
holder.select(".sja_genesearchinput").style("margin", "0px");
|
|
35
|
+
}
|
|
36
|
+
mayRenderSampleTypeSelect() {
|
|
37
|
+
this.dom.sampleTypeDiv.selectAll("*").remove();
|
|
38
|
+
this.querySampleTypes = this.app.vocabApi.termdbConfig?.queries.geneExpression.sampleTypes;
|
|
39
|
+
this.querySampleTypesByTerms = this.app.vocabApi.termdbConfig?.queries.geneExpression.sampleTypesByTerms;
|
|
40
|
+
if (Array.isArray(this.querySampleTypes) && this.querySampleTypes.length >= 2 || this.querySampleTypesByTerms) {
|
|
41
|
+
const table = table2col({ holder: this.dom.sampleTypeDiv, margin: "0px 0px 15px 0px" });
|
|
42
|
+
const [td1, td2] = table.addRow();
|
|
43
|
+
td1.text("Sample Type");
|
|
44
|
+
td2.style("padding-left", "10px");
|
|
45
|
+
if (this.querySampleTypesByTerms) {
|
|
46
|
+
this.sampleTypeSelect = renderSampleTypesByTermsSelect(
|
|
47
|
+
td2,
|
|
48
|
+
this.querySampleTypesByTerms,
|
|
49
|
+
this.app.vocabApi.termdbConfig
|
|
50
|
+
);
|
|
51
|
+
} else {
|
|
52
|
+
this.sampleTypeSelect = renderSampleTypeSelect(td2, this.querySampleTypes, this.app.vocabApi.termdbConfig);
|
|
53
|
+
}
|
|
54
|
+
}
|
|
55
|
+
}
|
|
56
|
+
async selectGene(geneSearch) {
|
|
57
|
+
const gene = geneSearch?.geneSymbol;
|
|
58
|
+
if (!gene) throw new Error("No gene selected");
|
|
59
|
+
const sampleTypes = this.querySampleTypesByTerms ? getSelectedSampleTypesByTerms(this.sampleTypeSelect, this.querySampleTypesByTerms) : getSelectedSampleTypes(this.sampleTypeSelect) || this.querySampleTypes;
|
|
60
|
+
if (this.sampleTypeSelect && !sampleTypes?.length) {
|
|
61
|
+
return;
|
|
62
|
+
}
|
|
63
|
+
const unit = getGEunit(this.app.vocabApi);
|
|
64
|
+
const name = `${gene} ${unit}`;
|
|
65
|
+
const term = { gene, name, type: TermTypes.GENE_EXPRESSION, sampleTypes };
|
|
66
|
+
if (this.querySampleTypesByTerms) {
|
|
67
|
+
const sampleTypeLabel = getSampleTypeLabelByTerms(this.sampleTypeSelect);
|
|
68
|
+
if (sampleTypeLabel) {
|
|
69
|
+
term.sampleTypeLabel = sampleTypeLabel;
|
|
70
|
+
term.name += ` (${sampleTypeLabel})`;
|
|
71
|
+
}
|
|
72
|
+
}
|
|
73
|
+
this.callback(term);
|
|
74
|
+
}
|
|
75
|
+
};
|
|
76
|
+
|
|
77
|
+
export {
|
|
78
|
+
SearchHandler
|
|
79
|
+
};
|
|
80
|
+
//# sourceMappingURL=chunk-YOBTHZVU.js.map
|
|
@@ -0,0 +1,217 @@
|
|
|
1
|
+
import {
|
|
2
|
+
dofetch,
|
|
3
|
+
dofetch2
|
|
4
|
+
} from "./chunk-GP4VLNMZ.js";
|
|
5
|
+
import {
|
|
6
|
+
contigNameNoChr2
|
|
7
|
+
} from "./chunk-57Z4VYLM.js";
|
|
8
|
+
|
|
9
|
+
// tracks/hic/data/parseData.ts
|
|
10
|
+
async function hicParseFile(hic, debugmode, errList = []) {
|
|
11
|
+
if (debugmode) window["hic"] = hic;
|
|
12
|
+
if (hic.tklst) {
|
|
13
|
+
const lst = [];
|
|
14
|
+
for (const t of hic.tklst) {
|
|
15
|
+
if (!t.type) {
|
|
16
|
+
errList.push("type missing from one of the tracks accompanying HiC");
|
|
17
|
+
} else {
|
|
18
|
+
t.iscustom = true;
|
|
19
|
+
lst.push(t);
|
|
20
|
+
}
|
|
21
|
+
}
|
|
22
|
+
if (lst.length) {
|
|
23
|
+
hic.tklst = lst;
|
|
24
|
+
} else {
|
|
25
|
+
delete hic.tklst;
|
|
26
|
+
}
|
|
27
|
+
}
|
|
28
|
+
if (hic.enzyme) {
|
|
29
|
+
if (hic.genome.hicenzymefragment) {
|
|
30
|
+
let frag = null;
|
|
31
|
+
for (const f of hic.genome.hicenzymefragment) {
|
|
32
|
+
if (f.enzyme == hic.enzyme) {
|
|
33
|
+
frag = f;
|
|
34
|
+
break;
|
|
35
|
+
}
|
|
36
|
+
}
|
|
37
|
+
if (frag) {
|
|
38
|
+
hic.enzymefile = frag.file;
|
|
39
|
+
} else {
|
|
40
|
+
errList.push("unknown enzyme: " + hic.enzyme);
|
|
41
|
+
delete hic.enzyme;
|
|
42
|
+
}
|
|
43
|
+
} else {
|
|
44
|
+
errList.push("no enzyme fragment information available for this genome");
|
|
45
|
+
delete hic.enzyme;
|
|
46
|
+
}
|
|
47
|
+
}
|
|
48
|
+
try {
|
|
49
|
+
if (hic.sv && hic.sv.file) {
|
|
50
|
+
const re = await dofetch(hic.hostURL + "/textfile", {
|
|
51
|
+
method: "POST",
|
|
52
|
+
body: JSON.stringify({ file: hic.sv.file, jwt: hic.jwt })
|
|
53
|
+
});
|
|
54
|
+
const data2 = re.json();
|
|
55
|
+
const [err2, header, items] = parseSV(data2.text);
|
|
56
|
+
if (err2) throw { message: "Error parsing SV: " + err2 };
|
|
57
|
+
hic.sv.header = header;
|
|
58
|
+
hic.sv.items = items;
|
|
59
|
+
}
|
|
60
|
+
const data = await dofetch2("hicstat?" + (hic.file ? "file=" + hic.file : "url=" + hic.url));
|
|
61
|
+
if (data.error) {
|
|
62
|
+
errList.push(data.error);
|
|
63
|
+
return;
|
|
64
|
+
}
|
|
65
|
+
const err = hicparsestat(hic, data.out);
|
|
66
|
+
if (err) throw { message: err };
|
|
67
|
+
} catch (err) {
|
|
68
|
+
errList.push(err.message || err);
|
|
69
|
+
if (err.stack) {
|
|
70
|
+
console.log(err.stack);
|
|
71
|
+
}
|
|
72
|
+
}
|
|
73
|
+
return hic;
|
|
74
|
+
}
|
|
75
|
+
function parseSV(txt) {
|
|
76
|
+
const lines = txt.trim().split(/\r?\n/);
|
|
77
|
+
const [err, header] = parseSVheader(lines[0]);
|
|
78
|
+
if (err) return ["header error: " + err];
|
|
79
|
+
const items = [];
|
|
80
|
+
for (let i = 1; i < lines.length; i++) {
|
|
81
|
+
const line = lines[i];
|
|
82
|
+
if (line[0] == "#") continue;
|
|
83
|
+
const [e, m] = parseSVline(line, header);
|
|
84
|
+
if (e) return ["line " + (i + 1) + " error: " + e];
|
|
85
|
+
items.push(m);
|
|
86
|
+
}
|
|
87
|
+
return [null, header, items];
|
|
88
|
+
}
|
|
89
|
+
function parseSVheader(line) {
|
|
90
|
+
const header = line.toLowerCase().split(" ");
|
|
91
|
+
if (header.length <= 1) return "invalid file header for fusions";
|
|
92
|
+
const htry = (...lst) => {
|
|
93
|
+
for (const a of lst) {
|
|
94
|
+
const j = header.indexOf(a);
|
|
95
|
+
if (j != -1) return j;
|
|
96
|
+
}
|
|
97
|
+
return -1;
|
|
98
|
+
};
|
|
99
|
+
let i = htry("chr_a", "chr1", "chra");
|
|
100
|
+
if (i == -1) return "chr_A missing from header";
|
|
101
|
+
header[i] = "chr1";
|
|
102
|
+
i = htry("chr_b", "chr2", "chrb");
|
|
103
|
+
if (i == -1) return "chr_B missing from header";
|
|
104
|
+
header[i] = "chr2";
|
|
105
|
+
i = htry("pos_a", "position_a", "position1", "posa");
|
|
106
|
+
if (i == -1) return "pos_a missing from header";
|
|
107
|
+
header[i] = "position1";
|
|
108
|
+
i = htry("pos_b", "position_b", "position2", "posb");
|
|
109
|
+
if (i == -1) return "pos_b missing from header";
|
|
110
|
+
header[i] = "position2";
|
|
111
|
+
i = htry("strand_a", "orta", "orienta");
|
|
112
|
+
if (i == -1) return "strand_a missing from header";
|
|
113
|
+
header[i] = "strand1";
|
|
114
|
+
i = htry("strand_b", "ortb", "orientb");
|
|
115
|
+
if (i == -1) return "strand_b missing from header";
|
|
116
|
+
header[i] = "strand2";
|
|
117
|
+
i = htry("numreadsa");
|
|
118
|
+
if (i != -1) header[i] = "reads1";
|
|
119
|
+
i = htry("numreadsb");
|
|
120
|
+
if (i != -1) header[i] = "reads2";
|
|
121
|
+
return [null, header];
|
|
122
|
+
}
|
|
123
|
+
function parseSVline(line, header) {
|
|
124
|
+
const lst = line.split(" ");
|
|
125
|
+
const m = {};
|
|
126
|
+
for (let j = 0; j < header.length; j++) {
|
|
127
|
+
m[header[j]] = lst[j];
|
|
128
|
+
}
|
|
129
|
+
if (!m.chr1) return ["missing chr1"];
|
|
130
|
+
if (m.chr1.toLowerCase().indexOf("chr") != 0) {
|
|
131
|
+
m.chr1 = "chr" + m.chr1;
|
|
132
|
+
}
|
|
133
|
+
if (!m.chr2) return ["missing chr2"];
|
|
134
|
+
if (m.chr2.toLowerCase().indexOf("chr") != 0) {
|
|
135
|
+
m.chr2 = "chr" + m.chr2;
|
|
136
|
+
}
|
|
137
|
+
if (!m.position1) return ["missing position1"];
|
|
138
|
+
let v = Number.parseInt(m.position1);
|
|
139
|
+
if (Number.isNaN(v) || v <= 0) return ["position1 invalid value"];
|
|
140
|
+
m.position1 = v;
|
|
141
|
+
if (!m.position2) return ["missing position2"];
|
|
142
|
+
v = Number.parseInt(m.position2);
|
|
143
|
+
if (Number.isNaN(v) || v <= 0) return ["position2 invalid value"];
|
|
144
|
+
m.position2 = v;
|
|
145
|
+
if (m.reads1) {
|
|
146
|
+
v = Number.parseInt(m.reads1);
|
|
147
|
+
if (Number.isNaN(v)) return ["reads1 invalid value"];
|
|
148
|
+
m.reads1 = v;
|
|
149
|
+
}
|
|
150
|
+
if (m.reads2) {
|
|
151
|
+
v = Number.parseInt(m.reads2);
|
|
152
|
+
if (Number.isNaN(v)) return ["reads2 invalid value"];
|
|
153
|
+
m.reads2 = v;
|
|
154
|
+
}
|
|
155
|
+
return [null, m];
|
|
156
|
+
}
|
|
157
|
+
function hicparsestat(hic, j) {
|
|
158
|
+
if (!j) return "cannot stat hic file";
|
|
159
|
+
hic.normalization = j.normalization;
|
|
160
|
+
hic.version = j.version;
|
|
161
|
+
if (!j.Chromosomes) return "Chromosomes not found in file stat";
|
|
162
|
+
if (!Array.isArray(j.chrorder)) return ".chrorder[] missing";
|
|
163
|
+
if (j.chrorder.length == 0) return ".chrorder[] empty array";
|
|
164
|
+
hic.chrorder = j.chrorder;
|
|
165
|
+
if (!j["Base pair-delimited resolutions"]) return "Base pair-delimited resolutions not found in file stat";
|
|
166
|
+
if (!Array.isArray(j["Base pair-delimited resolutions"])) return "Base pair-delimited resolutions should be array";
|
|
167
|
+
hic.bpresolution = j["Base pair-delimited resolutions"];
|
|
168
|
+
if (!j["Fragment-delimited resolutions"]) return "Fragment-delimited resolutions not found in file stat";
|
|
169
|
+
if (!Array.isArray(j["Fragment-delimited resolutions"])) return "Fragment-delimited resolutions is not array";
|
|
170
|
+
hic.fragresolution = j["Fragment-delimited resolutions"];
|
|
171
|
+
const chrlst = [];
|
|
172
|
+
for (const chr in j.Chromosomes) {
|
|
173
|
+
chrlst.push(chr);
|
|
174
|
+
}
|
|
175
|
+
const [nochrcount, haschrcount] = contigNameNoChr2(hic.genome, chrlst);
|
|
176
|
+
if (nochrcount + haschrcount == 0) return "chromosome names do not match with genome build";
|
|
177
|
+
if (nochrcount > 0) {
|
|
178
|
+
hic.nochr = true;
|
|
179
|
+
for (let i = 0; i < hic.chrorder.length; i++) hic.chrorder[i] = "chr" + hic.chrorder[i];
|
|
180
|
+
}
|
|
181
|
+
hic.chrlst = [];
|
|
182
|
+
for (const chr of hic.genome.majorchrorder) {
|
|
183
|
+
const c2 = hic.nochr ? chr.replace("chr", "") : chr;
|
|
184
|
+
if (chrlst.indexOf(c2) != -1) {
|
|
185
|
+
hic.chrlst.push(chr);
|
|
186
|
+
}
|
|
187
|
+
}
|
|
188
|
+
}
|
|
189
|
+
function hicparsefragdata(items) {
|
|
190
|
+
const id2coord = /* @__PURE__ */ new Map();
|
|
191
|
+
let min = null, max;
|
|
192
|
+
for (const i of items) {
|
|
193
|
+
if (!i.rest || !i.rest[0]) {
|
|
194
|
+
return ["items[].rest data problem"];
|
|
195
|
+
}
|
|
196
|
+
const id = Number.parseInt(i.rest[0]);
|
|
197
|
+
if (Number.isNaN(id)) {
|
|
198
|
+
return [i.start + "." + i.stop + " invalid fragment id: " + i.rest[0]];
|
|
199
|
+
}
|
|
200
|
+
id2coord.set(id, [i.start, i.stop]);
|
|
201
|
+
if (min == null) {
|
|
202
|
+
min = id;
|
|
203
|
+
max = id;
|
|
204
|
+
} else {
|
|
205
|
+
min = Math.min(min, id);
|
|
206
|
+
max = Math.max(max, id);
|
|
207
|
+
}
|
|
208
|
+
}
|
|
209
|
+
return [null, id2coord, min, max];
|
|
210
|
+
}
|
|
211
|
+
|
|
212
|
+
export {
|
|
213
|
+
hicParseFile,
|
|
214
|
+
hicparsestat,
|
|
215
|
+
hicparsefragdata
|
|
216
|
+
};
|
|
217
|
+
//# sourceMappingURL=chunk-ZTT6ZHU5.js.map
|
|
@@ -0,0 +1,70 @@
|
|
|
1
|
+
import {
|
|
2
|
+
appInit,
|
|
3
|
+
vocabInit
|
|
4
|
+
} from "./chunk-K7HFOAR7.js";
|
|
5
|
+
import "./chunk-HJ6L54YS.js";
|
|
6
|
+
import "./chunk-KV4W2ACA.js";
|
|
7
|
+
import "./chunk-FSWBNSQD.js";
|
|
8
|
+
import "./chunk-7XZA2XR2.js";
|
|
9
|
+
import "./chunk-DD3DWHUY.js";
|
|
10
|
+
import "./chunk-EEB5VE2A.js";
|
|
11
|
+
import "./chunk-6RRZRISL.js";
|
|
12
|
+
import "./chunk-2KM4PRQM.js";
|
|
13
|
+
import "./chunk-GP4VLNMZ.js";
|
|
14
|
+
import "./chunk-6AFMWQXZ.js";
|
|
15
|
+
import "./chunk-CME6DYDH.js";
|
|
16
|
+
import {
|
|
17
|
+
TermTypes
|
|
18
|
+
} from "./chunk-57Z4VYLM.js";
|
|
19
|
+
import "./chunk-WINIL2KN.js";
|
|
20
|
+
import "./chunk-PF4DSFDR.js";
|
|
21
|
+
import "./chunk-7X6NF7NI.js";
|
|
22
|
+
import "./chunk-W5J3LTYS.js";
|
|
23
|
+
import "./chunk-Z2ZITHT4.js";
|
|
24
|
+
import "./chunk-4OLM3KSB.js";
|
|
25
|
+
import "./chunk-6XKAOSQE.js";
|
|
26
|
+
import "./chunk-TLT4YIG3.js";
|
|
27
|
+
import "./chunk-5R63Q5KH.js";
|
|
28
|
+
import "./chunk-I6Y4O3RR.js";
|
|
29
|
+
import "./chunk-Q5RDQNIT.js";
|
|
30
|
+
import "./chunk-DQC5FFGV.js";
|
|
31
|
+
import "./chunk-HS5PO5ZQ.js";
|
|
32
|
+
|
|
33
|
+
// termdb/handlers/cohort.ts
|
|
34
|
+
var SearchHandler = class {
|
|
35
|
+
init(opts) {
|
|
36
|
+
this.callback = opts.callback;
|
|
37
|
+
this.app = opts.app;
|
|
38
|
+
const holder = opts.holder.append("div").style("padding", "10px 0px");
|
|
39
|
+
const cohorts = this.app.vocabApi.app?.opts?.opts?.cohorts0;
|
|
40
|
+
if (!cohorts?.length) return;
|
|
41
|
+
const terms = cohorts.map((cohort) => {
|
|
42
|
+
const term = {
|
|
43
|
+
id: cohort.id,
|
|
44
|
+
name: cohort.name,
|
|
45
|
+
type: TermTypes.COHORT,
|
|
46
|
+
filter0: cohort.filter,
|
|
47
|
+
isleaf: true,
|
|
48
|
+
parent_id: null
|
|
49
|
+
};
|
|
50
|
+
return term;
|
|
51
|
+
});
|
|
52
|
+
const vocabApi = vocabInit({ vocab: { terms } });
|
|
53
|
+
appInit({
|
|
54
|
+
holder,
|
|
55
|
+
vocabApi,
|
|
56
|
+
state: {
|
|
57
|
+
nav: { header_mode: "hide_search" }
|
|
58
|
+
},
|
|
59
|
+
tree: {
|
|
60
|
+
click_term: (term) => {
|
|
61
|
+
this.callback(term);
|
|
62
|
+
}
|
|
63
|
+
}
|
|
64
|
+
});
|
|
65
|
+
}
|
|
66
|
+
};
|
|
67
|
+
export {
|
|
68
|
+
SearchHandler
|
|
69
|
+
};
|
|
70
|
+
//# sourceMappingURL=cohort-RF4FT2NT.js.map
|