@sjcrh/proteinpaint-client 2.210.0 → 2.210.1
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/2dmaf-7VZ536T5.js +1367 -0
- package/dist/AggMatrixInput-UTUOXTGA.js +406 -0
- package/dist/AggregateMatrix-X75HUZYO.js +41 -0
- package/dist/AppHeader-X2DR6VSM.js +830 -0
- package/dist/BoxPlot-NQMPJICU.js +1211 -0
- package/dist/CorrelationVolcano-IDBUJH2E.js +617 -0
- package/dist/Cuminc-BYFIMOLO.js +1219 -0
- package/dist/DE-BI7DHHW4.js +89 -0
- package/dist/DEinput-W66CT4U2.js +501 -0
- package/dist/DM-62TEJA3C.js +90 -0
- package/dist/DifferentialAnalysis-PRTA6CYW.js +239 -0
- package/dist/Disco-4JQP3FRW.js +3389 -0
- package/dist/Disco.UI-6RHAA5KU.js +243 -0
- package/dist/DmrPlot-VYQYMTQ7.js +362 -0
- package/dist/GB-LULUM5LH.js +1392 -0
- package/dist/GB-LULUM5LH.js.map +7 -0
- package/dist/GSEA-DT3SYXOZ.js +875 -0
- package/dist/GeneExpInput-UILWAGRH.js +42 -0
- package/dist/Geomap-AFKEGMR5.js +84 -0
- package/dist/HicApp-APDL5POY.js +2245 -0
- package/dist/IDCViewer-DQXAORHT.js +10812 -0
- package/dist/NumBinaryEditor-OUVIOEH7.js +279 -0
- package/dist/NumBinaryEditor.unit.spec-VBX2X4CT.js +312 -0
- package/dist/NumContEditor-JVPRBZPW.js +105 -0
- package/dist/NumContEditor.unit.spec-EQNB6RMI.js +164 -0
- package/dist/NumCustomBinEditor-E2SXZDF4.js +33 -0
- package/dist/NumCustomBinEditor.unit.spec-VLR7MGNL.js +397 -0
- package/dist/NumDiscreteEditor-CUA55FU3.js +170 -0
- package/dist/NumDiscreteEditor.unit.spec-7IPCMUDQ.js +233 -0
- package/dist/NumRegularBinEditor-CWU7YBEP.js +33 -0
- package/dist/NumRegularBinEditor.unit.spec-RGV3EUPC.js +278 -0
- package/dist/NumSplineEditor-PC5X7AUJ.js +210 -0
- package/dist/NumSplineEditor.unit.spec-QCR3RL5W.js +224 -0
- package/dist/NumericDensity-CFUEE5ZN.js +33 -0
- package/dist/NumericDensity.unit.spec-JOCVEC32.js +418 -0
- package/dist/NumericHandler-VL2Z55KF.js +34 -0
- package/dist/NumericHandler.unit.spec-ULM5FSSA.js +214 -0
- package/dist/ProteomeInput-3WKTVCYT.js +388 -0
- package/dist/Regression-M7AQTYXL.js +1416 -0
- package/dist/RunChart2-54SVOXJR.js +749 -0
- package/dist/SC-QRWDGHB2.js +1183 -0
- package/dist/Violin-2AD6QRJB.js +1081 -0
- package/dist/Volcano-T57VFSWR.js +2456 -0
- package/dist/Volcano-T57VFSWR.js.map +7 -0
- package/dist/Wsi-U3U3EILE.js +629 -0
- package/dist/adSandbox-S3JP7XF3.js +33 -0
- package/dist/animatedBubbleChart-LZKNERIM.js +547 -0
- package/dist/app-2MERLGNJ.js +42 -0
- package/dist/app-ZNSUUOFJ.js +32 -0
- package/dist/app.js +14 -14
- package/dist/bam-ESRPS4TQ.js +876 -0
- package/dist/barchart-BPUEO4RK.js +42 -0
- package/dist/barchart2-Z36PNSM2.js +309 -0
- package/dist/block-GEG4UUOU.js +6250 -0
- package/dist/block.init-SB6OX35E.js +33 -0
- package/dist/block.mds.expressionrank-2JLMS334.js +354 -0
- package/dist/block.mds.geneboxplot-BZMGG6G3.js +823 -0
- package/dist/block.mds.junction-636PWE2O.js +1539 -0
- package/dist/block.mds.svcnv-S4L2HMZW.js +6796 -0
- package/dist/block.svg-A7EABUXG.js +159 -0
- package/dist/block.tk.aicheck-KNFJVUTW.js +278 -0
- package/dist/block.tk.ase-BPU25OLX.js +360 -0
- package/dist/block.tk.bam-VC4CZCUS.js +1901 -0
- package/dist/block.tk.bedgraphdot-FQS4Z4RC.js +379 -0
- package/dist/block.tk.bigwig.ui-7STXSD3X.js +206 -0
- package/dist/block.tk.hicstraw-CVDCOMPP.js +818 -0
- package/dist/block.tk.junction-PG4RZFH3.js +2358 -0
- package/dist/block.tk.junction.textmatrixui-JRW4ZJIK.js +194 -0
- package/dist/block.tk.ld-DLDP2NHJ.js +94 -0
- package/dist/block.tk.menu-PWGFMKBQ.js +1024 -0
- package/dist/block.tk.pgv-HOBOXQIN.js +938 -0
- package/dist/brainImaging-GUQTOHQF.js +555 -0
- package/dist/brainRegions-JWBIBCTG.js +217 -0
- package/dist/bubbleHeatmap-EUO3DUVT.js +378 -0
- package/dist/cellTypeBubbleHeatmap-TIBGPZTB.js +278 -0
- package/dist/chunk-3CGAABHZ.js +176 -0
- package/dist/chunk-3ELYMSGO.js +26 -0
- package/dist/chunk-3QL3U6FU.js +2853 -0
- package/dist/chunk-3TV5WWUN.js +339 -0
- package/dist/chunk-4Y5W26UF.js +424 -0
- package/dist/chunk-5XE3WSUX.js +6360 -0
- package/dist/chunk-665X7R7S.js +382 -0
- package/dist/chunk-6MQPXWOR.js +55 -0
- package/dist/chunk-7DSL65G7.js +14 -0
- package/dist/chunk-A6F3CSXP.js +626 -0
- package/dist/chunk-AB6JQFIQ.js +129 -0
- package/dist/chunk-ACOHIDWO.js +240 -0
- package/dist/chunk-AIVPAC5Q.js +102 -0
- package/dist/chunk-AKKJFMW5.js +4375 -0
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- package/dist/chunk-CSAS3PVJ.js +24956 -0
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- package/dist/chunk-GLPTPX45.js +203 -0
- package/dist/chunk-GPY6SBCX.js +339 -0
- package/dist/chunk-GWHIKECP.js +1731 -0
- package/dist/chunk-GWVVEOYX.js +263 -0
- package/dist/chunk-HDV3LHCN.js +379 -0
- package/dist/chunk-HGXSYPU6.js +2327 -0
- package/dist/chunk-HMKEVTRM.js +446 -0
- package/dist/chunk-HPCKKXRK.js +1233 -0
- package/dist/chunk-J5JBHGRN.js +31 -0
- package/dist/chunk-JHOGTGIS.js +1988 -0
- package/dist/chunk-KCX54MGS.js +480 -0
- package/dist/chunk-KVRSO2OZ.js +34 -0
- package/dist/chunk-M4PUW3ML.js +243 -0
- package/dist/chunk-ME325OQC.js +562 -0
- package/dist/chunk-NJWNKBRC.js +468 -0
- package/dist/chunk-O5FUHCNU.js +397 -0
- package/dist/chunk-ODHQPTHU.js +134 -0
- package/dist/chunk-PTQ4GQCS.js +692 -0
- package/dist/chunk-PUSSP76H.js +70 -0
- package/dist/chunk-Q3PAXUCU.js +54 -0
- package/dist/chunk-QWBKN2IC.js +80 -0
- package/dist/chunk-R4E7BXC6.js +49 -0
- package/dist/chunk-SDYFM3UL.js +274 -0
- package/dist/chunk-SP6WCXY6.js +217 -0
- package/dist/chunk-SRTZQOK7.js +102 -0
- package/dist/chunk-T4RYLTR3.js +178 -0
- package/dist/chunk-TANWA6SU.js +54 -0
- package/dist/chunk-TBIHBC5V.js +170 -0
- package/dist/chunk-TGTCOCPF.js +1278 -0
- package/dist/chunk-TOFOT2BN.js +294 -0
- package/dist/chunk-UOYIPBTX.js +217 -0
- package/dist/chunk-USULBM4V.js +2784 -0
- package/dist/chunk-UYKJOBRO.js +1616 -0
- package/dist/chunk-UYKJOBRO.js.map +7 -0
- package/dist/chunk-V3WSMWBF.js +123 -0
- package/dist/chunk-VTHZGUSZ.js +2146 -0
- package/dist/chunk-WMQDFVJK.js +103 -0
- package/dist/chunk-WTQQWFV4.js +38 -0
- package/dist/chunk-XDLKYVYU.js +276 -0
- package/dist/chunk-XNJN5J3U.js +37 -0
- package/dist/chunk-XQLOEZ7T.js +158 -0
- package/dist/chunk-Y3SDMRDX.js +119 -0
- package/dist/chunk-Y5FE3G6J.js +518 -0
- package/dist/chunk-YMEWZVRG.js +237 -0
- package/dist/chunk-YPHFEKWI.js +1339 -0
- package/dist/chunk-Z4HW3FEE.js +272 -0
- package/dist/cohort-NYFUILFO.js +70 -0
- package/dist/condition-6M4AVISY.js +327 -0
- package/dist/controls-LMTWS3SY.js +34 -0
- package/dist/controls.config-4PK7HLFJ.js +34 -0
- package/dist/correlation-X6GB6ITK.js +95 -0
- package/dist/customdata.inputui-MDG3BTTG.js +284 -0
- package/dist/dataDownload-TFRI3VFM.js +329 -0
- package/dist/databrowser.ui-L2K7VVDW.js +425 -0
- package/dist/dictionary-MS6R3VNY.js +113 -0
- package/dist/dnaMethylation-2KYSQWNE.js +33 -0
- package/dist/dnaMethylation.integration.spec-2BHNKOGN.js +198 -0
- package/dist/dofetch-BETN7HEX.js +48 -0
- package/dist/e2pca-QC2EI5JM.js +344 -0
- package/dist/ep-BTRMR4OT.js +1249 -0
- package/dist/expclust.gdc.spec-C5ZMBCGO.js +302 -0
- package/dist/facet-LPXKLX53.js +519 -0
- package/dist/gb-PHJ2SM5D.js +81 -0
- package/dist/geneExpClustering-OXZJHEPD.js +244 -0
- package/dist/geneExpression-54RGEGML.js +310 -0
- package/dist/geneExpression-FLBQXMSX.js +33 -0
- package/dist/geneExpression.unit.spec-ZCE7G6HI.js +128 -0
- package/dist/geneORA-TELI5AFV.js +273 -0
- package/dist/geneRanking-7YZA5GNG.js +548 -0
- package/dist/geneVariant-NJYUEY4C.js +36 -0
- package/dist/geneVariant-VKWTXUMK.js +289 -0
- package/dist/geneVariant.integration.spec-RWYP523U.js +503 -0
- package/dist/genefusion.ui-B6J7I3RA.js +303 -0
- package/dist/geneset-VG4SFYML.js +203 -0
- package/dist/genomeBrowser.spec-5IS5Y2NG.js +276 -0
- package/dist/grin2-3T6KRC34.js +70 -0
- package/dist/grin2-FOOH736B.js +949 -0
- package/dist/hierCluster-WLAFGZAT.js +55 -0
- package/dist/hierCluster-XBL2TOOL.js +59 -0
- package/dist/hierCluster.config-VCBRBGDZ.js +36 -0
- package/dist/hierCluster.integration.spec-TNJD2QT6.js +483 -0
- package/dist/hierCluster.interactivity-PEEJ3BRC.js +49 -0
- package/dist/hierCluster.renderers-7ESGKIGM.js +19 -0
- package/dist/imagePlot-LWL6JMKM.js +156 -0
- package/dist/importPlot-CLBY6QZN.js +8 -0
- package/dist/isoformExpression-36P3BBN7.js +35 -0
- package/dist/isoformExpression.unit.spec-SF2SPTRC.js +237 -0
- package/dist/junction-B7DSIG4E.js +36 -0
- package/dist/junction.customTerm-7VZS4JDE.js +16 -0
- package/dist/junction.unit.spec-4MWU36MR.js +182 -0
- package/dist/launch.adhoc-3B34GV4S.js +37 -0
- package/dist/leftlabel.sample-6OM5H67E.js +258 -0
- package/dist/lollipop-SL2F5G6K.js +166 -0
- package/dist/maf-FRYGN5GR.js +455 -0
- package/dist/maftimeline-3UFWS73J.js +587 -0
- package/dist/matrix-DDKSOJ4C.js +59 -0
- package/dist/matrix-H2ZH2QKC.js +54 -0
- package/dist/matrix.cells-JTMC35SK.js +26 -0
- package/dist/matrix.config-EUBXWEBS.js +37 -0
- package/dist/matrix.data-CO5RBWY5.js +23 -0
- package/dist/matrix.groups-AKOJ2W6U.js +26 -0
- package/dist/matrix.integration.spec-66KNZO3S.js +3160 -0
- package/dist/matrix.interactivity-DY5YJIYB.js +37 -0
- package/dist/matrix.layout-MQQNHBI2.js +39 -0
- package/dist/matrix.legend-CGU7T6GF.js +20 -0
- package/dist/matrix.renderers-HC7PJN4B.js +34 -0
- package/dist/matrix.serieses-W4L6ZO37.js +19 -0
- package/dist/matrix.sort-T74DWFB2.js +26 -0
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- package/dist/mavb-3CL5OHWB.js +727 -0
- package/dist/mds.fimo-2RFJQKJM.js +513 -0
- package/dist/mds.samplescatterplot-X6CXMY4C.js +1545 -0
- package/dist/mds.survivalplot-57NIKSSH.js +477 -0
- package/dist/multivalue-3TUGYL4J.js +83 -0
- package/dist/numericDictTermCluster-RLX5CLTN.js +63 -0
- package/dist/oncomatrix-COK76MJN.js +290 -0
- package/dist/oncomatrix.spec-SO3ZN5BF.js +443 -0
- package/dist/plot.2dvaf-TETCE4VG.js +372 -0
- package/dist/plot.app-5YUAVZA4.js +36 -0
- package/dist/plot.barplot-JUGY5Z7A.js +97 -0
- package/dist/plot.boxplot-QZXICT7J.js +146 -0
- package/dist/plot.brainImaging-2F6E6QS4.js +51 -0
- package/dist/plot.disco-H4P4B6QS.js +99 -0
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- package/dist/plot.vaf2cov-UBMD2CN7.js +253 -0
- package/dist/polar2-AVEZM2T5.js +232 -0
- package/dist/profileForms-CUSUGTPC.js +941 -0
- package/dist/profilePlot-67Z7AXQ4.js +49 -0
- package/dist/proteinView-7K7VHGX3.js +1357 -0
- package/dist/proteomeCohortCompare-MRGH6HHI.js +912 -0
- package/dist/pseudbulk.unit.spec-ZHDL6GIM.js +86 -0
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- package/dist/singleCellCellType-QLAEBVN2.js +33 -0
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- package/dist/singleCellGeneExpression-IZ2PMDDL.js +33 -0
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- package/dist/singleCellNumericValue-NB3QFH7H.js +33 -0
- package/dist/singleCellNumericValue.unit.spec-ZKK2KWRQ.js +416 -0
- package/dist/singleCellPlot-ZU655L4Z.js +48 -0
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- package/dist/spliceevent.a53ss.diagram-FL2R6F22.js +146 -0
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- package/dist/stattable-R7O6OIMB.js +117 -0
- package/dist/studyCatalog-OMDE4JRD.js +414 -0
- package/dist/summarizeCnvGeneexp-A7HW6FJI.js +158 -0
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- /package/dist/{selectGenomeWithTklst-ZZUJ7AQ7.js.map → selectGenomeWithTklst-3BG2ZPPN.js.map} +0 -0
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- /package/dist/{spliceevent.a53ss.diagram-C32IEFMU.js.map → spliceevent.a53ss.diagram-FL2R6F22.js.map} +0 -0
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- /package/dist/{summarizeCnvGeneexp-OVZO6KIB.js.map → summarizeCnvGeneexp-A7HW6FJI.js.map} +0 -0
- /package/dist/{summarizeGeneexpSurvival-KVQ4JGWK.js.map → summarizeGeneexpSurvival-ODI4HGFH.js.map} +0 -0
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- /package/dist/{summarizeMutationSurvival-J7H7L4FX.js.map → summarizeMutationSurvival-7IHNURLC.js.map} +0 -0
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- /package/dist/{tvs.dt-PLRMK7OT.js.map → tvs.dt-43A4SSLG.js.map} +0 -0
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// gdc/DE.ts
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async function init(arg, holder, genomes) {
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const useGenome = arg.genome || "hg38";
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// plots/DEinput.ts
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var DEinputPlot = class _DEinputPlot extends PlotBase {
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constructor(opts, api) {
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}
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getState(appState) {
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}
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return {
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termfilter: appState.termfilter,
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config,
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_scope_: appState._scope_
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};
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}
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async init(appState) {
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const state = this.getState(appState);
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this.termType = state.config.termType || TermTypes.GENE_EXPRESSION;
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this.dom.header?.html(`Differential ${termType2label(this.termType)}`);
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await this.renderExpressionSourceUI();
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}
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// TODO: handle errors
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async main() {
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if (!this.state) return;
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|
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this.dom.preAnalysis.selectAll("*").remove();
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if (!this.expressionSource || this.expressionSource === "pseudobulk" && !this.pseudobulk) {
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this.dom.table.style("display", "none");
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this.dom.addGroup.style("display", "none");
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this.dom.submit.style("display", "none");
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return;
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}
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this.dom.addGroup.style("display", "inline-block");
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this.maySeedGroups();
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this.hasCohort0 = this.groups.some((g) => g.filter.lst.some((item) => item.tvs?.term.type == "cohort"));
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await this.makeGroupsUI();
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this.mayRenderSubmit();
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await this.mayAutoSubmit();
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}
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/* config.groups[] lets a caller launch this ui with prebuilt groups, each defined by a mass
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filter, instead of requiring the user to build both groups by hand. seeded only once: main() reruns
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on every state change, and a seeded group is editable like any other, so a rerun must not undo a
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rename, edit, or deletion */
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maySeedGroups() {
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if (this.groupsSeeded) return;
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this.groupsSeeded = true;
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if (!this.state.config.groups?.length) return;
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const massFilter = getNormalRoot(excludeFilterByTag(structuredClone(this.state.termfilter.filter), "cohortFilter"));
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for (const g of this.state.config.groups) {
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this.addNewGroup(filterJoin([massFilter, getNormalRoot(g.filter)]), this.groups, g.name, g.color);
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}
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}
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/* config.autoSubmit runs the analysis on the seeded groups without waiting for a click, for a caller
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that already knows the groups to compare. runs only once: main() reruns on every state change, and
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138
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each run is a round trip to termdb/DE */
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async mayAutoSubmit() {
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if (!this.state.config.autoSubmit || this.autoSubmitted) return;
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if (this.dom.submit.style("display") == "none") return;
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this.autoSubmitted = true;
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await this.clickSubmit(this.getSubmitGroups());
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}
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145
|
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/** the groups as compared by the analysis: a lone group is compared against all other samples */
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|
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getSubmitGroups() {
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if (this.groups.length != 1) return this.groups;
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const group = this.groups[0];
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return [
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group,
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{
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name: "Not in " + group.name,
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color: "#ccc",
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|
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filter: negateFilter(group.filter)
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|
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}
|
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|
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];
|
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|
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}
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|
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async renderExpressionSourceUI() {
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|
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const config = this.app.vocabApi.termdbConfig;
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|
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if (!this.isGE) {
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const dm = config.queries?.dnaMethylation;
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|
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if (!dm?.promoter && !dm?.elementTypes?.length)
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|
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throw new Error("No DNA methylation data configured for differential analysis");
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|
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this.expressionSource = "bulk";
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|
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return;
|
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|
-
}
|
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|
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const hasBulk = !!config.queries?.rnaseqGeneCount;
|
|
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|
-
const terms = config.termType2terms?.[TermTypeGroups.PSEUDOBULK] || [];
|
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|
-
const hasPseudobulk = terms.length > 0;
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|
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if (!hasBulk && !hasPseudobulk)
|
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|
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throw new Error("No gene expression count data configured for differential analysis");
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|
-
if (hasBulk && !hasPseudobulk) {
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|
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this.expressionSource = "bulk";
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|
-
return;
|
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175
|
-
}
|
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|
-
if (!hasBulk) {
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|
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this.expressionSource = "pseudobulk";
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|
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this.renderPseudobulkSelection(this.dom.expressionSource, terms);
|
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|
-
return;
|
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180
|
-
}
|
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|
-
const tabs = [
|
|
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|
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{
|
|
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|
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label: "Bulk RNA-seq",
|
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|
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active: true,
|
|
185
|
-
callback: async () => {
|
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186
|
-
this.expressionSource = "bulk";
|
|
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|
-
await this.main();
|
|
188
|
-
}
|
|
189
|
-
},
|
|
190
|
-
{
|
|
191
|
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label: "Single-cell pseudobulk",
|
|
192
|
-
callback: async (_event, tab) => {
|
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193
|
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this.expressionSource = "pseudobulk";
|
|
194
|
-
tab.contentHolder.selectAll("*").remove();
|
|
195
|
-
this.renderPseudobulkSelection(tab.contentHolder, terms);
|
|
196
|
-
await this.main();
|
|
197
|
-
}
|
|
198
|
-
}
|
|
199
|
-
];
|
|
200
|
-
await new Tabs({ holder: this.dom.expressionSource, tabs }).main();
|
|
201
|
-
}
|
|
202
|
-
renderPseudobulkSelection(holder, terms) {
|
|
203
|
-
const assayMap = /* @__PURE__ */ new Map();
|
|
204
|
-
for (const term of terms) {
|
|
205
|
-
if (!assayMap.has(term.assay)) assayMap.set(term.assay, /* @__PURE__ */ new Map());
|
|
206
|
-
const memberMap = assayMap.get(term.assay);
|
|
207
|
-
if (!memberMap.has(term.memberId)) memberMap.set(term.memberId, []);
|
|
208
|
-
memberMap.get(term.memberId).push(term);
|
|
209
|
-
}
|
|
210
|
-
const renderAssay = (assayHolder, assay, memberMap) => {
|
|
211
|
-
assayHolder.selectAll("*").remove();
|
|
212
|
-
const renderMember = (memberHolder, memberId, memberTerms) => {
|
|
213
|
-
memberHolder.selectAll("*").remove();
|
|
214
|
-
memberHolder.append("div").style("opacity", 0.7).text(`Select from ${memberId}:`);
|
|
215
|
-
make_radios({
|
|
216
|
-
holder: memberHolder,
|
|
217
|
-
inputName: `sjpp-de-pseudobulk-${this.id}-${assay}-${memberId}`,
|
|
218
|
-
options: memberTerms.map((term) => ({
|
|
219
|
-
label: term.name,
|
|
220
|
-
value: term.id,
|
|
221
|
-
checked: this.pseudobulk?.assay === assay && this.pseudobulk?.memberId === memberId && this.pseudobulk?.category === (term.category || term.id),
|
|
222
|
-
testid: `sjpp-de-pseudobulk-category-${term.id}`
|
|
223
|
-
})),
|
|
224
|
-
styles: { display: "block", padding: "3px 5px" },
|
|
225
|
-
callback: async (value) => {
|
|
226
|
-
const term = memberTerms.find((term2) => term2.id == value);
|
|
227
|
-
this.pseudobulk = { assay, memberId, category: term.category || term.id };
|
|
228
|
-
await this.main();
|
|
229
|
-
}
|
|
230
|
-
});
|
|
231
|
-
};
|
|
232
|
-
if (memberMap.size === 1) {
|
|
233
|
-
const [memberId, memberTerms] = memberMap.entries().next().value;
|
|
234
|
-
renderMember(assayHolder, memberId, memberTerms);
|
|
235
|
-
} else {
|
|
236
|
-
const memberTabs = Array.from(memberMap, ([memberId, memberTerms]) => ({
|
|
237
|
-
label: memberId,
|
|
238
|
-
callback: (_event, tab) => renderMember(tab.contentHolder, memberId, memberTerms)
|
|
239
|
-
}));
|
|
240
|
-
new Tabs({ holder: assayHolder, tabs: memberTabs }).main();
|
|
241
|
-
}
|
|
242
|
-
};
|
|
243
|
-
if (assayMap.size === 1) {
|
|
244
|
-
const [assay, memberMap] = Array.from(assayMap)[0];
|
|
245
|
-
holder.append("div").text("Single-cell pseudobulk " + termType2label(assay));
|
|
246
|
-
renderAssay(holder.append("div"), assay, memberMap);
|
|
247
|
-
} else {
|
|
248
|
-
const assayTabs = Array.from(assayMap, ([assay, memberMap]) => ({
|
|
249
|
-
label: termType2label(assay),
|
|
250
|
-
callback: (_event, tab) => renderAssay(tab.contentHolder, assay, memberMap)
|
|
251
|
-
}));
|
|
252
|
-
new Tabs({ holder, tabs: assayTabs, linePosition: "right", tabsPosition: "vertical" }).main();
|
|
253
|
-
}
|
|
254
|
-
}
|
|
255
|
-
async makeGroupsUI() {
|
|
256
|
-
if (!this.filterPrompt) {
|
|
257
|
-
this.filterPrompt = await filterPromptInit({
|
|
258
|
-
holder: this.dom.addGroup,
|
|
259
|
-
vocabApi: this.app.vocabApi,
|
|
260
|
-
emptyLabel: "Add group",
|
|
261
|
-
header_mode: this.opts?.header_mode,
|
|
262
|
-
callback: async (f) => {
|
|
263
|
-
const filter2 = getNormalRoot(f);
|
|
264
|
-
this.addNewGroup(filter2, this.groups);
|
|
265
|
-
await this.main();
|
|
266
|
-
},
|
|
267
|
-
debug: this.opts.debug
|
|
268
|
-
});
|
|
269
|
-
}
|
|
270
|
-
const filter = structuredClone(this.state?.termfilter?.filter);
|
|
271
|
-
this.filterPrompt.main(excludeFilterByTag(filter, "cohortFilter"));
|
|
272
|
-
if (!this.groups.length) {
|
|
273
|
-
this.dom.table.style("display", "none");
|
|
274
|
-
return;
|
|
275
|
-
}
|
|
276
|
-
this.dom.table.style("display", "block").selectAll("*").remove();
|
|
277
|
-
const tableArg = {
|
|
278
|
-
div: this.dom.table,
|
|
279
|
-
columns: [
|
|
280
|
-
{},
|
|
281
|
-
// blank column to add delete buttons
|
|
282
|
-
{
|
|
283
|
-
label: "NAME",
|
|
284
|
-
editCallback: async (i, cell) => {
|
|
285
|
-
const newName = cell.value;
|
|
286
|
-
const index = this.groups.findIndex((group) => group.name == newName);
|
|
287
|
-
if (index != -1) {
|
|
288
|
-
alert(`Group named ${newName} already exists`);
|
|
289
|
-
await this.main();
|
|
290
|
-
} else {
|
|
291
|
-
this.groups[i].name = newName;
|
|
292
|
-
await this.main();
|
|
293
|
-
}
|
|
294
|
-
}
|
|
295
|
-
},
|
|
296
|
-
{
|
|
297
|
-
label: "COLOR",
|
|
298
|
-
editCallback: async (i, cell) => {
|
|
299
|
-
this.groups[i].color = cell.color;
|
|
300
|
-
this.main();
|
|
301
|
-
}
|
|
302
|
-
},
|
|
303
|
-
// dataset may rename what a row counts (GDC: cases, not samples)
|
|
304
|
-
{ label: `#${uiLabel(this.app.vocabApi.termdbConfig?.uiLabels, "Sample", "Sample").toUpperCase()}` },
|
|
305
|
-
{ label: "FILTER" }
|
|
306
|
-
],
|
|
307
|
-
rows: [],
|
|
308
|
-
striped: false,
|
|
309
|
-
// no alternating row bg color so delete button appears more visible
|
|
310
|
-
showLines: false
|
|
311
|
-
};
|
|
312
|
-
for (const g of this.groups) {
|
|
313
|
-
tableArg.rows.push([
|
|
314
|
-
{},
|
|
315
|
-
// blank cell to add delete button
|
|
316
|
-
{ value: g.name },
|
|
317
|
-
// to allow click to show <input>
|
|
318
|
-
{ color: g.color },
|
|
319
|
-
{ value: "" },
|
|
320
|
-
// filled in asynchronously below, so one slow count does not hold up the table
|
|
321
|
-
{}
|
|
322
|
-
// blank cell to show filter ui
|
|
323
|
-
]);
|
|
324
|
-
}
|
|
325
|
-
renderTable(tableArg);
|
|
326
|
-
for (const [i, row] of tableArg.rows.entries()) {
|
|
327
|
-
row[0].__td.append("div").attr("class", "sja_menuoption").style("padding", "1px 6px").html("×").on("click", () => {
|
|
328
|
-
this.groups.splice(i, 1);
|
|
329
|
-
this.main();
|
|
330
|
-
});
|
|
331
|
-
this.app.vocabApi.getFilteredSampleCount(this.groups[i].filter, this.hasCohort0 ? null : this.state.termfilter.filter0).then((n) => row[3].__td.text(n)).catch((e) => row[3].__td.text("n/a").attr("title", e?.message || e));
|
|
332
|
-
const group = this.groups[i];
|
|
333
|
-
filterInit({
|
|
334
|
-
holder: row[4].__td,
|
|
335
|
-
vocabApi: this.app.vocabApi,
|
|
336
|
-
header_mode: "hide_search",
|
|
337
|
-
callback: (f) => {
|
|
338
|
-
if (!f || f.lst.length == 0) {
|
|
339
|
-
const i2 = this.groups.findIndex((g) => g.name == group.name);
|
|
340
|
-
this.groups.splice(i2, 1);
|
|
341
|
-
} else {
|
|
342
|
-
group.filter = f;
|
|
343
|
-
}
|
|
344
|
-
this.main();
|
|
345
|
-
}
|
|
346
|
-
}).main(group.filter);
|
|
347
|
-
}
|
|
348
|
-
this.dom.addGroup.select(".sja_new_filter_btn").style("pointer-events", "auto").style("opacity", 1);
|
|
349
|
-
}
|
|
350
|
-
addNewGroup(filter, groups, name, color2) {
|
|
351
|
-
if (!groups) throw "groups is missing";
|
|
352
|
-
if (!name) {
|
|
353
|
-
const base = "New group";
|
|
354
|
-
name = base;
|
|
355
|
-
for (let i = 0; ; i++) {
|
|
356
|
-
name = base + (i === 0 ? "" : " " + i);
|
|
357
|
-
if (!groups.find((g) => g.name === name)) break;
|
|
358
|
-
}
|
|
359
|
-
}
|
|
360
|
-
const newGroup = {
|
|
361
|
-
name,
|
|
362
|
-
filter,
|
|
363
|
-
color: color2 || rgb(colorScale(groups.length)).formatHex()
|
|
364
|
-
};
|
|
365
|
-
groups.push(newGroup);
|
|
366
|
-
}
|
|
367
|
-
mayRenderSubmit() {
|
|
368
|
-
if (!this.groups.length || this.groups.length == 1 && this.hasCohort0) {
|
|
369
|
-
this.dom.submit.style("display", "none");
|
|
370
|
-
return;
|
|
371
|
-
}
|
|
372
|
-
this.dom.submit.style("display", "inline-block");
|
|
373
|
-
if (this.groups.length == 1) {
|
|
374
|
-
this.dom.submit.text(`Submit (${this.groups[0].name} vs others)`);
|
|
375
|
-
this.dom.submit.on("click", async () => {
|
|
376
|
-
await this.clickSubmit(this.getSubmitGroups());
|
|
377
|
-
});
|
|
378
|
-
} else if (this.groups.length == 2) {
|
|
379
|
-
this.dom.addGroup.select(".sja_new_filter_btn").style("pointer-events", "none").style("opacity", 0.5);
|
|
380
|
-
this.dom.submit.text(`Submit (${this.groups[0].name} vs ${this.groups[1].name})`);
|
|
381
|
-
this.dom.submit.on("click", async () => {
|
|
382
|
-
await this.clickSubmit(this.groups);
|
|
383
|
-
});
|
|
384
|
-
} else {
|
|
385
|
-
throw new Error("cannot exceed 2 groups");
|
|
386
|
-
}
|
|
387
|
-
}
|
|
388
|
-
async clickSubmit(groups) {
|
|
389
|
-
this.dom.loading.style("display", "block");
|
|
390
|
-
const samplelstTW = {
|
|
391
|
-
q: { groups: [] },
|
|
392
|
-
term: {
|
|
393
|
-
name: groups.map((g) => g.name).join(" vs "),
|
|
394
|
-
type: "samplelst",
|
|
395
|
-
values: {}
|
|
396
|
-
}
|
|
397
|
-
};
|
|
398
|
-
if (this.expressionSource === "pseudobulk") samplelstTW.pseudobulk = this.pseudobulk;
|
|
399
|
-
const filter0 = this.hasCohort0 ? null : this.state.termfilter.filter0;
|
|
400
|
-
const mapParent2Children = true;
|
|
401
|
-
for (const g of groups) {
|
|
402
|
-
const samples = await this.vocabApi.getFilteredSampleList(
|
|
403
|
-
filterJoin([g.filter, this.state.termfilter.filter]),
|
|
404
|
-
filter0,
|
|
405
|
-
mapParent2Children
|
|
406
|
-
);
|
|
407
|
-
const sampleIds = samples.map((s) => {
|
|
408
|
-
return { sampleId: s.id };
|
|
409
|
-
});
|
|
410
|
-
samplelstTW.q.groups.push({
|
|
411
|
-
name: g.name,
|
|
412
|
-
in: true,
|
|
413
|
-
values: sampleIds
|
|
414
|
-
});
|
|
415
|
-
samplelstTW.term.values[g.name] = {
|
|
416
|
-
color: g.color,
|
|
417
|
-
key: g.name,
|
|
418
|
-
label: g.name,
|
|
419
|
-
list: sampleIds
|
|
420
|
-
//samples need to be passed for the samplelst filter to work
|
|
421
|
-
};
|
|
422
|
-
}
|
|
423
|
-
const body = {
|
|
424
|
-
genome: this.app.vocabApi.vocab.genome,
|
|
425
|
-
dslabel: this.app.vocabApi.vocab.dslabel,
|
|
426
|
-
samplelst: { groups: samplelstTW.q.groups },
|
|
427
|
-
filter: this.state.termfilter.filter,
|
|
428
|
-
filter0,
|
|
429
|
-
preAnalysis: true
|
|
430
|
-
};
|
|
431
|
-
if (this.expressionSource === "pseudobulk") body.pseudobulk = this.pseudobulk;
|
|
432
|
-
const preAnalysisData = await dofetch3(this.isGE ? "termdb/DE" : "termdb/diffMeth", { body });
|
|
433
|
-
this.dom.loading.style("display", "none");
|
|
434
|
-
this.dom.preAnalysis.style("display", "block").selectAll("*").remove();
|
|
435
|
-
renderPreAnalysisData({
|
|
436
|
-
preAnalysisData,
|
|
437
|
-
samplelstTW,
|
|
438
|
-
groups: samplelstTW.q.groups,
|
|
439
|
-
holder: this.dom.preAnalysis,
|
|
440
|
-
termType: this.termType,
|
|
441
|
-
self: this
|
|
442
|
-
});
|
|
443
|
-
}
|
|
444
|
-
};
|
|
445
|
-
var DEinputInit = getCompInit(DEinputPlot);
|
|
446
|
-
var componentInit = DEinputInit;
|
|
447
|
-
var supportedTermTypes = /* @__PURE__ */ new Set([TermTypes.GENE_EXPRESSION, TermTypes.DNA_METHYLATION]);
|
|
448
|
-
async function getPlotConfig(opts, app) {
|
|
449
|
-
if (opts.termType && !supportedTermTypes.has(opts.termType))
|
|
450
|
-
throw new Error(`termType='${opts.termType}' is not supported by DEinput`);
|
|
451
|
-
const config = {
|
|
452
|
-
chartType: "DEinput",
|
|
453
|
-
// default keeps every existing caller on gene expression without passing anything
|
|
454
|
-
termType: opts.termType || TermTypes.GENE_EXPRESSION,
|
|
455
|
-
settings: {}
|
|
456
|
-
};
|
|
457
|
-
const c = copyMerge(config, opts);
|
|
458
|
-
if (c.groups) c.groups = await getValidGroups(c.groups, app);
|
|
459
|
-
return c;
|
|
460
|
-
}
|
|
461
|
-
async function getValidGroups(groups, app) {
|
|
462
|
-
if (!Array.isArray(groups)) throw "config.groups must be an array";
|
|
463
|
-
if (groups.length > 2) throw "config.groups[] cannot exceed 2 groups";
|
|
464
|
-
const names = /* @__PURE__ */ new Set();
|
|
465
|
-
for (const g of groups) {
|
|
466
|
-
if (!g?.filter) throw "config.groups[] entry is missing .filter{}";
|
|
467
|
-
if ("name" in g && typeof g.name != "string") throw "config.groups[].name must be a string";
|
|
468
|
-
if (!g.name) continue;
|
|
469
|
-
if (names.has(g.name)) throw `duplicate config.groups[].name='${g.name}'`;
|
|
470
|
-
names.add(g.name);
|
|
471
|
-
}
|
|
472
|
-
const validated = [];
|
|
473
|
-
for (const g of groups) {
|
|
474
|
-
const filter = getNormalRoot(g.filter);
|
|
475
|
-
if (!filter.lst.length) throw "config.groups[] entry has a blank .filter{}";
|
|
476
|
-
if (app?.vocabApi) await Promise.all(rehydrateFilter(filter, app.vocabApi));
|
|
477
|
-
const name = g.name || getUnusedGroupName(names);
|
|
478
|
-
names.add(name);
|
|
479
|
-
const valid = Object.assign({}, g, { filter, name });
|
|
480
|
-
if ("color" in g) {
|
|
481
|
-
const c = color(g.color);
|
|
482
|
-
if (!c) throw `invalid config.groups[].color='${g.color}'`;
|
|
483
|
-
valid.color = c.formatHex();
|
|
484
|
-
}
|
|
485
|
-
validated.push(valid);
|
|
486
|
-
}
|
|
487
|
-
return validated;
|
|
488
|
-
}
|
|
489
|
-
function getUnusedGroupName(names) {
|
|
490
|
-
const base = "New group";
|
|
491
|
-
for (let i = 0; ; i++) {
|
|
492
|
-
const name = base + (i === 0 ? "" : " " + i);
|
|
493
|
-
if (!names.has(name)) return name;
|
|
494
|
-
}
|
|
495
|
-
}
|
|
496
|
-
export {
|
|
497
|
-
DEinputInit,
|
|
498
|
-
componentInit,
|
|
499
|
-
getPlotConfig
|
|
500
|
-
};
|
|
501
|
-
//# sourceMappingURL=DEinput-O6LBFAAH.js.map
|
package/dist/DM-C7VN3RWB.js
DELETED
|
@@ -1,90 +0,0 @@
|
|
|
1
|
-
import {
|
|
2
|
-
appInit
|
|
3
|
-
} from "./chunk-CT4IG5IR.js";
|
|
4
|
-
import "./chunk-Y7V5AIUH.js";
|
|
5
|
-
import "./chunk-QD75Q5LM.js";
|
|
6
|
-
import "./chunk-D6UBH77N.js";
|
|
7
|
-
import "./chunk-S2ICJ3RZ.js";
|
|
8
|
-
import "./chunk-4G73CMUL.js";
|
|
9
|
-
import "./chunk-X46YA4CB.js";
|
|
10
|
-
import "./chunk-SKMFMGCD.js";
|
|
11
|
-
import "./chunk-CKOU3P27.js";
|
|
12
|
-
import "./chunk-PRZWSBMA.js";
|
|
13
|
-
import "./chunk-55FABQU2.js";
|
|
14
|
-
import "./chunk-HJ6L54YS.js";
|
|
15
|
-
import "./chunk-KV4W2ACA.js";
|
|
16
|
-
import "./chunk-UXD6G6G4.js";
|
|
17
|
-
import "./chunk-ELJX3QIQ.js";
|
|
18
|
-
import "./chunk-3FEP6B5T.js";
|
|
19
|
-
import "./chunk-EEB5VE2A.js";
|
|
20
|
-
import "./chunk-6RRZRISL.js";
|
|
21
|
-
import "./chunk-2KM4PRQM.js";
|
|
22
|
-
import "./chunk-VA57CUC7.js";
|
|
23
|
-
import "./chunk-BK6UDL7F.js";
|
|
24
|
-
import "./chunk-KIAMLQ7S.js";
|
|
25
|
-
import "./chunk-SB36AUG7.js";
|
|
26
|
-
import "./chunk-WINIL2KN.js";
|
|
27
|
-
import "./chunk-PF4DSFDR.js";
|
|
28
|
-
import "./chunk-7X6NF7NI.js";
|
|
29
|
-
import "./chunk-W5J3LTYS.js";
|
|
30
|
-
import "./chunk-Z2ZITHT4.js";
|
|
31
|
-
import "./chunk-4OLM3KSB.js";
|
|
32
|
-
import "./chunk-FXQXCOII.js";
|
|
33
|
-
import "./chunk-TLT4YIG3.js";
|
|
34
|
-
import "./chunk-5R63Q5KH.js";
|
|
35
|
-
import "./chunk-I6Y4O3RR.js";
|
|
36
|
-
import "./chunk-Q5RDQNIT.js";
|
|
37
|
-
import "./chunk-DQC5FFGV.js";
|
|
38
|
-
import "./chunk-HS5PO5ZQ.js";
|
|
39
|
-
|
|
40
|
-
// gdc/DM.ts
|
|
41
|
-
async function init(arg, holder, genomes) {
|
|
42
|
-
const useGenome = arg.genome || "hg38";
|
|
43
|
-
const useDslabel = arg.dslabel || "GDC";
|
|
44
|
-
const genome = genomes[useGenome];
|
|
45
|
-
const massApi = await appInit({
|
|
46
|
-
genome,
|
|
47
|
-
holder,
|
|
48
|
-
state: {
|
|
49
|
-
genome: useGenome,
|
|
50
|
-
dslabel: useDslabel,
|
|
51
|
-
termfilter: { filter0: arg.filter0 },
|
|
52
|
-
nav: { activeTab: 1, header_mode: "hidden" },
|
|
53
|
-
// an embedder may supply prebuilt groups, see config.groups[] in plots/DEinput.ts.
|
|
54
|
-
// DEinput is the group-building submission ui, shared with DE and switched by termType;
|
|
55
|
-
// it launches the 'differentialAnalysis' results chart once groups are submitted
|
|
56
|
-
plots: arg.state?.plots || [{ chartType: "DEinput", termType: "dnaMethylation" }]
|
|
57
|
-
},
|
|
58
|
-
opts: Object.assign(
|
|
59
|
-
{
|
|
60
|
-
// todo additional customizations
|
|
61
|
-
// dictionary:{header:'Select a variable to build Correlation Plot'}
|
|
62
|
-
// some way to make gene exp violin/boxplot to use log scale by default, but numeric dict term should not
|
|
63
|
-
},
|
|
64
|
-
arg.opts || {}
|
|
65
|
-
),
|
|
66
|
-
app: arg.opts?.app || {}
|
|
67
|
-
});
|
|
68
|
-
const api = {
|
|
69
|
-
update: async (updateArg) => {
|
|
70
|
-
if (!massApi) return;
|
|
71
|
-
if ("filter0" in updateArg) {
|
|
72
|
-
massApi.dispatch({
|
|
73
|
-
type: "app_refresh",
|
|
74
|
-
subactions: [
|
|
75
|
-
{
|
|
76
|
-
type: "filter_replace",
|
|
77
|
-
filter0: updateArg.filter0
|
|
78
|
-
}
|
|
79
|
-
]
|
|
80
|
-
});
|
|
81
|
-
}
|
|
82
|
-
},
|
|
83
|
-
triggerAbort: (reason = "") => massApi.triggerAbort(reason)
|
|
84
|
-
};
|
|
85
|
-
return api;
|
|
86
|
-
}
|
|
87
|
-
export {
|
|
88
|
-
init
|
|
89
|
-
};
|
|
90
|
-
//# sourceMappingURL=DM-C7VN3RWB.js.map
|