@sjcrh/proteinpaint-client 2.206.0 → 2.207.0

package/dist/databrowser.ui-4YE24U4B.js

@@ -0,0 +1,425 @@
+import {
+  isURL,
+  makeBtn,
+  makeFileUpload,
+  makePrompt,
+  makeResetBtn,
+  makeTextAreaInput,
+  makeTextInput
+} from "./chunk-5EBRF6Z7.js";
+import {
+  appInit
+} from "./chunk-DRKC4J62.js";
+import "./chunk-6EXPDXXV.js";
+import "./chunk-IYCSCSRS.js";
+import "./chunk-5UO7MKCO.js";
+import "./chunk-AEHBMP7F.js";
+import "./chunk-BMQDU7KN.js";
+import "./chunk-X46YA4CB.js";
+import "./chunk-SKMFMGCD.js";
+import "./chunk-ANGLZ4XR.js";
+import "./chunk-PRZWSBMA.js";
+import {
+  Tabs,
+  appear,
+  sayerror
+} from "./chunk-NQDF3U2C.js";
+import "./chunk-HJ6L54YS.js";
+import "./chunk-KV4W2ACA.js";
+import "./chunk-CCYVGZGI.js";
+import "./chunk-ELJX3QIQ.js";
+import "./chunk-N7DVQTPC.js";
+import "./chunk-EEB5VE2A.js";
+import "./chunk-6RRZRISL.js";
+import "./chunk-2KM4PRQM.js";
+import "./chunk-GRVO7RW4.js";
+import "./chunk-7CJKL3LK.js";
+import "./chunk-HZ3TCGBK.js";
+import "./chunk-IZUYLFOX.js";
+import "./chunk-WINIL2KN.js";
+import "./chunk-PF4DSFDR.js";
+import "./chunk-7X6NF7NI.js";
+import "./chunk-W5J3LTYS.js";
+import "./chunk-Z2ZITHT4.js";
+import "./chunk-4OLM3KSB.js";
+import "./chunk-FXQXCOII.js";
+import "./chunk-TLT4YIG3.js";
+import "./chunk-5R63Q5KH.js";
+import "./chunk-I6Y4O3RR.js";
+import "./chunk-Q5RDQNIT.js";
+import "./chunk-DQC5FFGV.js";
+import "./chunk-HS5PO5ZQ.js";
+
+// src/databrowser/dictionary.parse.js
+function parseDictionary(input) {
+  const terms = {};
+  const lines = input.trim().split(/\r?\n/);
+  const header = lines[0].split("	");
+  const term_idIndex = header.findIndex((l) => l.toLowerCase().includes("term_id"));
+  const variableIndex = header.findIndex((l) => l.toLowerCase().includes("variable"));
+  if (term_idIndex != -1) parseDataDictionary(lines, header);
+  if (variableIndex != -1) parsePhenotree(lines, header);
+  if (variableIndex == -1 && term_idIndex == -1) {
+    throw `Unrecognized file format. Please check the header names.`;
+  }
+  function parseDataDictionary(lines2, header2) {
+    const parIdIndex = header2.findIndex((l) => l.toLowerCase().includes("parent_id"));
+    if (parIdIndex == -1) {
+      throw `Missing required 'parent_id' header`;
+    }
+    const nameIndex = header2.findIndex((l) => l.toLowerCase().includes("name"));
+    if (nameIndex == -1) {
+      throw `Missing required 'Name' header`;
+    }
+    const typeIndex = header2.findIndex((l) => {
+      const v = l.trim().toLowerCase();
+      return v === "type";
+    });
+    if (typeIndex == -1) {
+      throw `Missing required 'Type' header`;
+    }
+    const valuesIndex = header2.findIndex((l) => l.toLowerCase().includes("values"));
+    if (valuesIndex == -1) {
+      throw `Missing required 'Values' header`;
+    }
+    if (parIdIndex == -1 || nameIndex == -1 || typeIndex == -1 || valuesIndex == -1) {
+      throw `Missing required header(s)`;
+    }
+    const parentIds = /* @__PURE__ */ new Set();
+    for (const [i, line] of lines2.entries()) {
+      if (i === 0) continue;
+      const lineNum = i + 1;
+      try {
+        const cols = line.split("	");
+        for (const [i2, c] of cols.entries()) {
+          const colNum = i2 + 1;
+          let foundProblem;
+          if (i2 == valuesIndex) continue;
+          if (c == "" || c == "-") {
+            foundProblem = true;
+            throw `Blank or '-' entered for line ${lineNum}, column ${colNum}`;
+          }
+          if (foundProblem == true) throw `Invalid entry for line ${lineNum}, column ${colNum}`;
+        }
+        const termId = cols[term_idIndex];
+        const type = cols[typeIndex];
+        terms[termId] = {
+          id: termId,
+          name: cols[nameIndex].trim().replace(/"/g, ""),
+          parent_id: cols[parIdIndex] != "root" ? cols[parIdIndex] : null,
+          type: cols[typeIndex] != "non graphable" ? cols[typeIndex] : null
+        };
+        parentIds.add(terms[termId].parent_id);
+        if (type == "categorical") {
+          terms[termId].values = {};
+        }
+        const values = cols[valuesIndex].trim().replace(/"/g, "").split(";");
+        for (const x of values) {
+          const v = x.trim();
+          if (v == "") continue;
+          const segments = v.split("=");
+          const key = segments.shift();
+          const label = segments.join("=");
+          if (!label) throw `Values="${v}" in line ${lineNum} not in a key = value format.`;
+          if (!terms[termId].values) terms[termId].values = {};
+          terms[termId].values[key] = { label };
+        }
+        const numValues = Object.keys(terms[termId].values).length;
+        terms[termId].groupsetting = { disabled: numValues < 3 };
+        validateNumericTermCategories(terms[termId]);
+      } catch (e) {
+        throw `Line ${lineNum} error: ${e}`;
+      }
+    }
+    for (const t in terms) terms[t].isleaf = !parentIds.has(terms[t].id);
+  }
+  function parsePhenotree(lines2, header2) {
+    if (variableIndex == -1) {
+      throw `Missing required 'Variable' header`;
+    }
+    const typeIndex = header2.findIndex((l) => {
+      const v = l.trim().toLowerCase();
+      return v === "type";
+    });
+    if (typeIndex == -1) {
+      throw `Missing required 'Type' header`;
+    }
+    const categoriesIndex = header2.findIndex((l) => l.toLowerCase().includes("categories"));
+    const levelColIndexes = header2.map((c, i) => c.toLowerCase().includes("level_") ? i : -1).filter((i) => i != -1);
+    if (!levelColIndexes.length) levelColIndexes.push(variableIndex);
+    const unitIndex = header2.findIndex((l) => l.toLowerCase().includes("unit"));
+    const sampleTypeIndex = header2.findIndex((l) => {
+      const v = l.trim().toLowerCase();
+      return v === "sample_type";
+    });
+    const additionalAttrIndexes = header2.findIndex((l) => l.toLowerCase().includes("additional attributes"));
+    const termNameToId = {};
+    const parentTermNames = /* @__PURE__ */ new Set();
+    const parent2ChildOrder = /* @__PURE__ */ new Map();
+    parent2ChildOrder.set(null, []);
+    for (const [i, line] of lines2.entries()) {
+      if (i === 0) continue;
+      const lineNum = i + 1;
+      try {
+        const cols = line.split("	");
+        const levelNames = levelColIndexes.map((i2) => cols[i2].trim().replace(/"/g, "")).filter((c) => c != "-");
+        if (levelNames.length != new Set(levelNames).size) {
+          throw `Non-unique levels in line ${lineNum}: ${JSON.stringify(levelNames)}`;
+        }
+        for (const [i2, lvlName] of levelNames.entries()) {
+          if (i2 == 0) {
+            if (parent2ChildOrder.get(null).indexOf(lvlName) == -1) parent2ChildOrder.get(null).push(lvlName);
+          }
+          if (i2 != levelNames.length - 1) {
+            if (!parent2ChildOrder.has(lvlName)) parent2ChildOrder.set(lvlName, []);
+          }
+          for (const n of levelNames) {
+            if (i2 == levelNames.indexOf(n) - 1) {
+              if (parent2ChildOrder.get(lvlName).indexOf(n) == -1) parent2ChildOrder.get(lvlName).push(n);
+            }
+          }
+        }
+        const name = levelNames.pop();
+        const firstDashIndex = cols.indexOf("-");
+        if (firstDashIndex != -1 && firstDashIndex < cols.indexOf(name)) {
+          throw `Blank or '-' value detected between levels in line ${lineNum}`;
+        }
+        const term = parseCategories(cols[typeIndex], cols[categoriesIndex], lineNum, name);
+        const id = cols[variableIndex] || name;
+        if (id in terms) {
+          const orig = terms[id];
+          throw `Error: Multiple config rows for term.id='${id}': lines# ${orig.lineNum} and ${lineNum}`;
+        }
+        terms[id] = {
+          id,
+          name,
+          type: term.type,
+          values: term.values,
+          groupsetting: term.groupsetting,
+          // *** temporary attributes to be deleted later ***
+          ancestry: levelNames.slice(),
+          // to be deleted later, used to fill in missing terms
+          parent_name: levelNames.pop() || null,
+          // will change this later to parent_id
+          lineNum
+          // to be deleted later
+        };
+        if (cols[unitIndex] != null) terms[id].unit = cols[unitIndex];
+        if (cols[sampleTypeIndex] != null) terms[id].sample_type = cols[sampleTypeIndex];
+        if (cols[additionalAttrIndexes]) {
+          Object.assign(terms[id], JSON.parse(cols[additionalAttrIndexes]));
+        }
+        termNameToId[name] = id;
+        parentTermNames.add(terms[id].parent_name);
+      } catch (e) {
+        throw `Line ${lineNum} error: ${e}`;
+      }
+    }
+    trackMissingTerms(termNameToId, terms, parentTermNames, parent2ChildOrder);
+    for (const id in terms) {
+      const term = terms[id];
+      term.child_order = parent2ChildOrder.get(term.parent_name).indexOf(term.name) + 1;
+      term.isleaf = !parentTermNames.has(term.name);
+      term.parent_id = termNameToId[term.parent_name] || null;
+      delete term.parent_name;
+      delete term.lineNum;
+      delete term.ancestry;
+    }
+  }
+  return { terms: Object.values(terms) };
+}
+function parseCategories(type, catJSON, lineNum, varName) {
+  if (!type) throw `No type provided for variable: ${varName} on line ${lineNum}`;
+  const term = {
+    type,
+    values: catJSON == "" || catJSON == void 0 ? {} : JSON.parse(catJSON)
+  };
+  validateNumericTermCategories(term);
+  if (term.type == "categorical") {
+    const numValues = Object.keys(term.values).length;
+    term.groupsetting = { disabled: numValues < 3 };
+  }
+  return term;
+}
+function trackMissingTerms(termNameToId, terms, parentTermNames, parent2ChildOrder) {
+  for (const id in terms) {
+    const term = terms[id];
+    for (const [i, name] of term.ancestry.entries()) {
+      if (name in termNameToId) {
+        const id2 = termNameToId[name];
+        const ancestor = terms[id2];
+        if (i - 1 < 0 && ancestor.parent_name || ancestor.parent_name != term.ancestry[i - 1]) {
+          throw `Different parents for term=${name}, '${term.ancestry[i - 1]}' and '${ancestor.parent_name}'`;
+        }
+        continue;
+      }
+      terms[name] = {
+        id: name,
+        name,
+        isleaf: false,
+        ancestry: term.ancestry.slice(0, i)
+      };
+      terms[name].parent_name = terms[name].ancestry.slice(-1)[0] || null;
+      termNameToId[name] = name;
+      parentTermNames.add(name);
+    }
+  }
+}
+function validateNumericTermCategories(term) {
+  if (term.type != "integer" && term.type != "float") return;
+  if (!term.values) return;
+  if (typeof term.values != "object") throw "numeric .values{} is not object";
+  for (const key in term.values) {
+    if (key == "") throw "Cannot use empty string as an uncomputable category";
+    const tmp = Number(key);
+    if (Number.isNaN(tmp)) {
+      throw `Uncomputable category of a numeric term is required to be a number (here uses non-numeric value of ${key}).`;
+    }
+    term.values[key].uncomputable = true;
+  }
+}
+
+// src/databrowser/databrowser.ui.js
+function init_databrowserUI(holder, debugmode) {
+  const wrapper = holder.append("div").style("margin", "20px 20px 20px 40px").style(
+    "font-family",
+    "'Lucida Sans', 'Lucida Sans Regular', 'Lucida Grande', 'Lucida Sans Unicode', Geneva, Verdana, sans-serif"
+  ).style("place-items", "center left").style("overflow", "hidden").classed("sjpp-app-ui", true);
+  const obj = {};
+  infoSection(wrapper);
+  makeSectionHeader(wrapper, "Data Dictionary");
+  const tabs_div = wrapper.append("div").style("margin-left", "2vw");
+  makeDataDictionaryTabs(tabs_div, obj);
+  const controlBtns_div = wrapper.append("div").style("display", "flex").style("align-items", "center").style("margin", "40px 0px 40px 130px");
+  submitButton(controlBtns_div, obj, wrapper, holder);
+  makeResetBtn(controlBtns_div, obj, ".databrowser_input");
+  if (debugmode) window.doms = obj;
+  return obj;
+}
+function infoSection(div) {
+  div.append("div").style("margin", "10px").style("opacity", "0.65").html(`
+			<ul>
+                <li>
+                    Please see the <a href="https://github.com/stjude/proteinpaint/wiki/Data-Browser" target="_blank">documentation</a> for more information.
+                </li>
+				<li>
+					Download an example data dictionary <a href="https://proteinpaint.stjude.org/ppdemo/databrowser/dictionaryDemoData.tar.gz" target="_self" "download>here</a>.
+				</li>
+            </ul>`);
+}
+function makeSectionHeader(div, text) {
+  const header = makePrompt(div, text);
+  header.style("font-size", "1.5em").style("color", "#003366").style("margin", "20px 10px 40px 10px").classed("sjpp-databrowser-section-header", true);
+  const hr = div.append("hr");
+  hr.style("color", "ligthgrey").style("margin", "-30px 0px 15px 0px").style("width", "50vw").style("opacity", "0.4");
+}
+function makeDataDictionaryTabs(tabs_div, obj) {
+  const tabs = [
+    {
+      label: "Select File",
+      active: true,
+      width: 95,
+      callback: async (event, tab) => {
+        tab.contentHolder.style("border", "none").style("display", "block");
+        appear(tab.contentHolder);
+        tab.contentHolder.append("div").html(`<p style="margin-left: 10px; opacity: 0.65;">Select a file from your computer.</p>`);
+        makeFileUpload2(tab.contentHolder, obj);
+        delete tab.callback;
+      }
+    },
+    {
+      label: "Paste Data",
+      active: false,
+      width: 95,
+      callback: async (event, tab) => {
+        tab.contentHolder.style("border", "none").style("display", "block");
+        appear(tab.contentHolder);
+        tab.contentHolder.append("div").html(
+          `<p style="margin-left: 10px; opacity: 0.65;">Paste data dictionary or phenotree in a tab delimited format.</p>`
+        );
+        makeCopyPasteInput(tab.contentHolder, obj);
+        delete tab.callback;
+      }
+    },
+    {
+      label: "File Path",
+      active: false,
+      width: 95,
+      callback: async (event, tab) => {
+        tab.contentHolder.style("border", "none").style("display", "block");
+        appear(tab.contentHolder);
+        tab.contentHolder.append("div").html(`<p style="margin-left: 10px; opacity: 0.65;">Provide a URL file path.</p>`);
+        makePrompt(tab.contentHolder, "URL");
+        makeTextEntryFilePathInput(tab.contentHolder, obj);
+        delete tab.callback;
+      }
+    }
+  ];
+  new Tabs({ holder: tabs_div, tabs }).main();
+}
+function makeTextEntryFilePathInput(div, obj) {
+  const filepath_div = div.append("div").style("display", "inline-block");
+  const filepath = makeTextInput(filepath_div).style("border", "1px solid rgb(138, 177, 212)").classed("databrowser_input", true).on("keyup", async () => {
+    const data = filepath.property("value").trim();
+    if (isURL(data)) {
+      const txt = await fetch(data).then((req) => req.text()).then((txt2) => {
+        obj.data = parseDictionary(txt2);
+      });
+    } else {
+    }
+  });
+}
+function makeFileUpload2(div, obj) {
+  const upload_div = div.append("div").style("display", "inline-block");
+  const upload = makeFileUpload(upload_div).classed("databrowser_input", true);
+  upload.on("change", (event) => {
+    const file = event.target.files[0];
+    const reader = new FileReader();
+    reader.onload = (event2) => {
+      obj.data = parseDictionary(event2.target.result);
+    };
+    reader.readAsText(file, "utf8");
+  });
+}
+function makeCopyPasteInput(div, obj) {
+  const paste_div = div.append("div").style("display", "block");
+  const paste = makeTextAreaInput({ div: paste_div, rows: 10 }).style("border", "1px solid rgb(138, 177, 212)").style("margin", "0px 0px 0px 20px").classed("databrowser_input", true).on("keyup", async () => {
+    obj.data = parseDictionary(paste.property("value").trim());
+  });
+}
+function submitButton(div, obj, wrapper, holder) {
+  const submit = makeBtn({
+    div,
+    text: "Create Data Browser",
+    color: "white",
+    backgroundColor: "#001aff",
+    border: "2px solid #001aff"
+  });
+  const errorMessage_div = div.append("div");
+  submit.style("margin-right", "10px").style("font-size", "16px").classed("sjpp-ui-submitBtn", true).attr("type", "submit").on("click", () => {
+    if (!obj.data || obj.data == void 0) {
+      const sayerrorDiv = errorMessage_div.append("div").style("display", "inline-block").style("max-width", "20vw");
+      sayerror(sayerrorDiv, "Please provide data");
+      setTimeout(() => sayerrorDiv.remove(), 3e3);
+    } else {
+      wrapper.remove();
+      appInit({
+        holder,
+        state: {
+          vocab: {
+            terms: obj.data.terms
+          },
+          plots: [
+            {
+              chartType: "dictionary"
+            }
+          ]
+        }
+      });
+    }
+  });
+}
+export {
+  init_databrowserUI
+};
+//# sourceMappingURL=databrowser.ui-4YE24U4B.js.map

package/dist/dictionary-LFOSXJGH.js

@@ -0,0 +1,113 @@
+import {
+  appInit
+} from "./chunk-NQDF3U2C.js";
+import "./chunk-HJ6L54YS.js";
+import "./chunk-KV4W2ACA.js";
+import "./chunk-CCYVGZGI.js";
+import "./chunk-ELJX3QIQ.js";
+import "./chunk-N7DVQTPC.js";
+import "./chunk-EEB5VE2A.js";
+import "./chunk-6RRZRISL.js";
+import "./chunk-2KM4PRQM.js";
+import "./chunk-GRVO7RW4.js";
+import "./chunk-7CJKL3LK.js";
+import "./chunk-HZ3TCGBK.js";
+import "./chunk-IZUYLFOX.js";
+import {
+  copyMerge,
+  getCompInit
+} from "./chunk-WINIL2KN.js";
+import "./chunk-PF4DSFDR.js";
+import "./chunk-7X6NF7NI.js";
+import "./chunk-W5J3LTYS.js";
+import "./chunk-Z2ZITHT4.js";
+import "./chunk-4OLM3KSB.js";
+import "./chunk-FXQXCOII.js";
+import "./chunk-TLT4YIG3.js";
+import "./chunk-5R63Q5KH.js";
+import "./chunk-I6Y4O3RR.js";
+import "./chunk-Q5RDQNIT.js";
+import "./chunk-DQC5FFGV.js";
+import "./chunk-HS5PO5ZQ.js";
+
+// plots/dictionary.js
+var MassDict = class _MassDict {
+  static type = "tree";
+  constructor(opts) {
+    this.type = _MassDict.type;
+    this.dom = {
+      holder: opts.holder.style("padding", "20px"),
+      header: opts.header
+    };
+  }
+  async init(appState) {
+    const config = appState.plots.find((p) => p.id === this.id) || {};
+    const opts = {
+      vocabApi: this.app.vocabApi,
+      holder: this.dom.holder,
+      state: this.getState(appState),
+      tree: {
+        click_term: (_term) => {
+          const term = _term.term || _term;
+          const _config = Object.assign({}, config?.spawnConfig, {
+            chartType: term.type == "survival" ? "survival" : "summary",
+            term: _term.term ? _term : { term }
+          });
+          this.app.dispatch({
+            type: "plot_create",
+            config: _config
+          });
+          this.app.dispatch({
+            type: "plot_delete",
+            id: this.id
+          });
+        }
+      }
+    };
+    if (config?.tree?.usecase) {
+      opts.tree.usecase = config.tree.usecase;
+    }
+    this.dom.holder.style("position", "relative");
+    const loadingDiv = this.dom.holder.append("div").attr("class", "sjpp-loading-overlay").style("display", "");
+    loadingDiv.append("div").attr("class", "sjpp-spinner");
+    try {
+      this.tree = await appInit(opts);
+    } finally {
+      loadingDiv.remove();
+    }
+  }
+  getState(appState) {
+    const config = appState.plots.find((p) => p.id === this.id) || {};
+    const tree = { usecase: { target: "dictionary" } };
+    if (config?.tree?.usecase?.specialCase) {
+      tree.usecase.specialCase = config.tree.usecase.specialCase;
+    }
+    return {
+      tree,
+      vocab: appState.vocab,
+      activeCohort: appState.activeCohort,
+      termfilter: appState.termfilter,
+      selectdTerms: appState.selectedTerms,
+      customTerms: appState.customTerms
+    };
+  }
+  main() {
+    if (this.dom.header) this.dom.header.text("Data Variables");
+    this.tree.dispatch({
+      type: "app_refresh",
+      state: this.state
+    });
+  }
+};
+var dictInit = getCompInit(MassDict);
+var componentInit = dictInit;
+function getPlotConfig(opts, app) {
+  const config = { hidePlotFilter: true };
+  return copyMerge(config, opts);
+}
+export {
+  componentInit,
+  dictInit,
+  getPlotConfig
+};
+//# sourceMappingURL=dictionary-LFOSXJGH.js.map

package/dist/dnaMethylation-2627GIZW.js

@@ -0,0 +1,33 @@
+import {
+  SearchHandler
+} from "./chunk-2XOBD4ZZ.js";
+import "./chunk-NQDF3U2C.js";
+import "./chunk-HJ6L54YS.js";
+import "./chunk-KV4W2ACA.js";
+import "./chunk-CCYVGZGI.js";
+import "./chunk-ELJX3QIQ.js";
+import "./chunk-N7DVQTPC.js";
+import "./chunk-EEB5VE2A.js";
+import "./chunk-6RRZRISL.js";
+import "./chunk-2KM4PRQM.js";
+import "./chunk-GRVO7RW4.js";
+import "./chunk-7CJKL3LK.js";
+import "./chunk-HZ3TCGBK.js";
+import "./chunk-IZUYLFOX.js";
+import "./chunk-WINIL2KN.js";
+import "./chunk-PF4DSFDR.js";
+import "./chunk-7X6NF7NI.js";
+import "./chunk-W5J3LTYS.js";
+import "./chunk-Z2ZITHT4.js";
+import "./chunk-4OLM3KSB.js";
+import "./chunk-FXQXCOII.js";
+import "./chunk-TLT4YIG3.js";
+import "./chunk-5R63Q5KH.js";
+import "./chunk-I6Y4O3RR.js";
+import "./chunk-Q5RDQNIT.js";
+import "./chunk-DQC5FFGV.js";
+import "./chunk-HS5PO5ZQ.js";
+export {
+  SearchHandler
+};
+//# sourceMappingURL=dnaMethylation-2627GIZW.js.map