@sjcrh/proteinpaint-client 2.180.0 → 2.180.1
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/2dmaf-TA6JJ2OR.js +1371 -0
- package/dist/AIProjectAdmin-SAYM2UUO.js +830 -0
- package/dist/AppHeader-7TNVJJA7.js +833 -0
- package/dist/BoxPlot-IAROTQ5L.js +1184 -0
- package/dist/CorrelationVolcano-ZFSDE4PA.js +617 -0
- package/dist/DifferentialAnalysis-X44YRQNQ.js +238 -0
- package/dist/Disco-YI2INE5R.js +3199 -0
- package/dist/Disco-YI2INE5R.js.map +7 -0
- package/dist/Disco.UI-YWYNQSRV.js +242 -0
- package/dist/DmrPlot-5V5QL4VS.js +151 -0
- package/dist/GB-3P67R4TI.js +1125 -0
- package/dist/HicApp-GKI7GS7Y.js +2248 -0
- package/dist/NumBinaryEditor-FNIEMKOY.js +266 -0
- package/dist/NumBinaryEditor.unit.spec-CDHPXF7F.js +284 -0
- package/dist/NumContEditor-XICKQ4Y6.js +105 -0
- package/dist/NumContEditor.unit.spec-DVFH4SZT.js +167 -0
- package/dist/NumCustomBinEditor-ZMND7YMB.js +36 -0
- package/dist/NumCustomBinEditor.unit.spec-WLWD4FV2.js +282 -0
- package/dist/NumDiscreteEditor-H2GG4COK.js +170 -0
- package/dist/NumDiscreteEditor.unit.spec-OEREZ6HB.js +200 -0
- package/dist/NumRegularBinEditor-YGMQV7ZW.js +36 -0
- package/dist/NumRegularBinEditor.unit.spec-ZUTXFGGA.js +225 -0
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- package/dist/NumSplineEditor.unit.spec-IDEB3KAY.js +197 -0
- package/dist/NumericDensity-5DDVJBBW.js +36 -0
- package/dist/NumericDensity.unit.spec-KTOY3EON.js +219 -0
- package/dist/NumericHandler-XBY7A7TV.js +37 -0
- package/dist/NumericHandler.unit.spec-KKBJDLZY.js +217 -0
- package/dist/RunChart2-F4652KYJ.js +756 -0
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- package/dist/Volcano-ZHQFH2MP.js +1092 -0
- package/dist/WSIViewer-MU3YXF7I.js +46972 -0
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- package/dist/adSandbox-7FIAWUBA.js +36 -0
- package/dist/alphaGenome-ACWK2XZL.js +173 -0
- package/dist/app-6V52ULRQ.js +47 -0
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- package/dist/barchart-BKWC5UXM.js +45 -0
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- package/dist/barchart.events-ZJSQB3KV.js +45 -0
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- package/dist/block.mds.svcnv-C5HEGIAK.js +6799 -0
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- package/dist/block.tk.bedgraphdot-5ZBNIQFY.js +382 -0
- package/dist/block.tk.bigwig.ui-V2GLBUU5.js +209 -0
- package/dist/block.tk.hicstraw-3NJLYMEJ.js +821 -0
- package/dist/block.tk.junction-C4CAACOA.js +2362 -0
- package/dist/block.tk.junction.textmatrixui-NJCGCHZ5.js +197 -0
- package/dist/block.tk.ld-PNX72F42.js +97 -0
- package/dist/block.tk.menu-AZ44SBLU.js +1027 -0
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- package/dist/brainImaging-5DO3465Z.js +421 -0
- package/dist/chat-346IEKTC.js +147 -0
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- package/dist/chunk-3W2QIOL2.js +4202 -0
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- package/dist/databrowser.ui-EY4MYHIN.js +419 -0
- package/dist/dictionary-RXSFDNVZ.js +98 -0
- package/dist/dnaMethylation-LBLLHMD4.js +36 -0
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- /package/dist/{singleCellGeneExpression-QPVTXR5W.js.map → singleCellCellType-OLXPVJE6.js.map} +0 -0
- /package/dist/{singleCellCellType.unit.spec-BAIWJSUP.js.map → singleCellCellType.unit.spec-MQH6HMRC.js.map} +0 -0
- /package/dist/{singleCellPlot-T2YNDBTX.js.map → singleCellGeneExpression-P2K6EAGJ.js.map} +0 -0
- /package/dist/{singleCellGeneExpression.unit.spec-Q5TS6VB5.js.map → singleCellGeneExpression.unit.spec-LMCCDVIY.js.map} +0 -0
- /package/dist/{snp-DAIHQXTJ.js.map → singleCellPlot-CP5QDUSH.js.map} +0 -0
- /package/dist/{singlecell-PAOWCTF5.js.map → singlecell-57YOSKNP.js.map} +0 -0
- /package/dist/{singlecell-B3NERPJ5.js.map → singlecell-FGDYQAVM.js.map} +0 -0
- /package/dist/{ssGSEA-5H4QBOY2.js.map → snp-BYMKURQO.js.map} +0 -0
- /package/dist/{snp.unit.spec-MXTEPR3Z.js.map → snp.unit.spec-6UGQYGQR.js.map} +0 -0
- /package/dist/{snplocus-PMAVBMTK.js.map → snplocus-AYSJ7PSU.js.map} +0 -0
- /package/dist/{spliceevent.a53ss.diagram-G6W7EY3Q.js.map → spliceevent.a53ss.diagram-BB73A4HM.js.map} +0 -0
- /package/dist/{spliceevent.exonskip.diagram-YHUNDN4M.js.map → spliceevent.exonskip.diagram-VWIAD5DQ.js.map} +0 -0
- /package/dist/{spliceevent.noeventdiagram-FN3PORQA.js.map → spliceevent.noeventdiagram-QACCAJS4.js.map} +0 -0
- /package/dist/{summarizeMutationDiagnosis-OAUXQ6HD.js.map → ssGSEA-REHCYQ7Z.js.map} +0 -0
- /package/dist/{ssGSEA.unit.spec-UBZGATIZ.js.map → ssGSEA.unit.spec-XJNHMFF5.js.map} +0 -0
- /package/dist/{summarizeCnvGeneexp-IR7HMUG3.js.map → summarizeCnvGeneexp-NDEEB7PV.js.map} +0 -0
- /package/dist/{summarizeGeneexpSurvival-INZXCZ37.js.map → summarizeGeneexpSurvival-ZCGBEB4C.js.map} +0 -0
- /package/dist/{summarizeMutationCnv-GZFJTCRN.js.map → summarizeMutationCnv-OOMN2AVW.js.map} +0 -0
- /package/dist/{summary-SAVKS777.js.map → summarizeMutationDiagnosis-B6TF3KU5.js.map} +0 -0
- /package/dist/{summarizeMutationSurvival-PT2BGPWD.js.map → summarizeMutationSurvival-Y2J6T2CS.js.map} +0 -0
- /package/dist/{survival-65IBMTWU.js.map → summary-O5LSGPWD.js.map} +0 -0
- /package/dist/{summary.integration.spec-LWO7Y4OP.js.map → summary.integration.spec-EH7FMP7B.js.map} +0 -0
- /package/dist/{summaryInput-SEIB7F3A.js.map → summaryInput-ZWURF7E2.js.map} +0 -0
- /package/dist/{sunburst-HCF2V66V.js.map → sunburst-ZDE5Q2SJ.js.map} +0 -0
- /package/dist/{termCollection-GYMOT2EE.js.map → survival-DTUOFMGJ.js.map} +0 -0
- /package/dist/{survival-RIV2T7KO.js.map → survival-XKLFNJF2.js.map} +0 -0
- /package/dist/{survival.integration.spec-2V2O4H7K.js.map → survival.integration.spec-J352BAT4.js.map} +0 -0
- /package/dist/{svgraph-XV52FOMN.js.map → svgraph-NZQ6Z4HS.js.map} +0 -0
- /package/dist/{svmr-BDAHM7UH.js.map → svmr-BPDWKVL2.js.map} +0 -0
- /package/dist/{table-5N2CRI36.js.map → table-6FOITCXA.js.map} +0 -0
- /package/dist/{tk-IOJVJ34S.js.map → termCollection-HFDUSCPL.js.map} +0 -0
- /package/dist/{termCollection-TZY6DOSP.js.map → termCollection-SWYRSREU.js.map} +0 -0
- /package/dist/{termCollection.unit.spec-VWHQ72DD.js.map → termCollection.unit.spec-ZSAAQS26.js.map} +0 -0
- /package/dist/{tvs.density-AQ5GD437.js.map → tk-D2YVENB3.js.map} +0 -0
- /package/dist/{tp.ui-JHPHESWM.js.map → tp.ui-XALNLDLX.js.map} +0 -0
- /package/dist/{tvs.dt-JPB46UPH.js.map → tvs.density-HSVPDDGA.js.map} +0 -0
- /package/dist/{tvs.numeric-PLNP7MBV.js.map → tvs.dt-TOZ47QR3.js.map} +0 -0
- /package/dist/{tvs.dtcnv.categorical-37TA7GCY.js.map → tvs.dtcnv.categorical-OZFNQFCX.js.map} +0 -0
- /package/dist/{tvs.dtcnv.continuous-X4K3RPYG.js.map → tvs.dtcnv.continuous-XCZJ7JOD.js.map} +0 -0
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- /package/dist/{violin-DCKEHIVC.js.map → tvs.numeric-AU4U3UXI.js.map} +0 -0
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} catch (e) {
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test.match(String(e), /missing chr, ref, alt, or fromWhat/, "Should throw when fromWhat is missing");
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}
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await handler.selectSnp({ ref: "A", alt: "T", fromWhat: "rs123" });
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} catch (e) {
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test.match(String(e), /missing chr, ref, alt, or fromWhat/, "Should throw when chr is missing");
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}
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try {
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await handler.selectSnp({ chr: "chr1", alt: "T", fromWhat: "rs123" });
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test.fail("Should throw when ref is missing");
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} catch (e) {
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test.match(String(e), /missing chr, ref, alt, or fromWhat/, "Should throw when ref is missing");
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}
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try {
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await handler.selectSnp({ chr: "chr1", ref: "A", fromWhat: "rs123" });
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test.fail("Should throw when alt is missing");
|
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} catch (e) {
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test.match(String(e), /missing chr, ref, alt, or fromWhat/, "Should throw when alt is missing");
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}
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test.end();
|
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});
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|
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(0, import_tape.default)("selectSnp() should throw when coordinate is missing", async (test) => {
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const handler = new SearchHandler();
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handler.callback = () => {
|
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};
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try {
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101
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await handler.selectSnp({
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chr: "chr17",
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ref: "G",
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alt: "A",
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fromWhat: "rs1234567"
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});
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test.fail("Should throw when coordinate is missing");
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} catch (e) {
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test.match(String(e), /missing coordinate of snp/, "Should throw expected message for missing coordinate");
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}
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test.end();
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});
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(0, import_tape.default)("selectSnp() should call callback with term object using start/stop coordinates", async (test) => {
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const handler = new SearchHandler();
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let selected;
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handler.callback = (t) => {
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selected = t;
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};
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const geneSearch = getGeneSearchWithCoordinates();
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await handler.selectSnp(geneSearch);
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test.equal(selected?.id, "rs1234567", "Should set id to fromWhat");
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test.equal(selected?.chr, "chr17", "Should pass chr");
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test.equal(selected?.start, 7670618, "Should pass start coordinate");
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test.equal(selected?.stop, 7670619, "Should pass stop coordinate");
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test.equal(selected?.ref, "G", "Should pass ref");
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test.deepEqual(selected?.alt, ["A"], "Should convert alt string to array");
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test.equal(selected?.name, "rs1234567", "Should set name to fromWhat");
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test.equal(selected?.type, "snp", "Should set type to snp");
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test.end();
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});
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(0, import_tape.default)("selectSnp() should call callback with term object using pos coordinate", async (test) => {
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const handler = new SearchHandler();
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let selected;
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handler.callback = (t) => {
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selected = t;
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};
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const geneSearch = getGeneSearchWithPos();
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await handler.selectSnp(geneSearch);
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test.equal(selected?.id, "BRCA2:c.68_69delAA", "Should set id to fromWhat");
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test.equal(selected?.chr, "chr13", "Should pass chr");
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test.equal(selected?.start, 32889611, "Should convert pos-1 to start");
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test.equal(selected?.stop, 32889612, "Should set stop to pos");
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test.equal(selected?.ref, "T", "Should pass ref");
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test.deepEqual(selected?.alt, ["C"], "Should convert alt string to array");
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test.equal(selected?.name, "BRCA2:c.68_69delAA", "Should set name to fromWhat");
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test.equal(selected?.type, "snp", "Should set type to snp");
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test.end();
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});
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(0, import_tape.default)("selectSnp() should handle alt as array when already in array format", async (test) => {
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const handler = new SearchHandler();
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let selected;
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handler.callback = (t) => {
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selected = t;
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};
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const geneSearch = getGeneSearchWithCoordinates({ alt: ["A", "T"] });
|
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await handler.selectSnp(geneSearch);
|
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test.deepEqual(selected?.alt, ["A", "T"], "Should preserve alt array when provided as array");
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|
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test.end();
|
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});
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(0, import_tape.default)("selectSnp() should handle various chromosome formats", async (test) => {
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const handler = new SearchHandler();
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|
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const chromosomes = ["chr1", "chr22", "chrX", "chrY", "chrM"];
|
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for (const chr of chromosomes) {
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let selected;
|
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handler.callback = (t) => {
|
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selected = t;
|
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|
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};
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|
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const geneSearch = getGeneSearchWithCoordinates({ chr });
|
|
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|
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await handler.selectSnp(geneSearch);
|
|
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|
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test.equal(selected?.chr, chr, `Should handle chromosome ${chr}`);
|
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|
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}
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|
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test.end();
|
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|
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});
|
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|
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//# sourceMappingURL=snp.unit.spec-MXTEPR3Z.js.map
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@@ -1,206 +0,0 @@
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import {
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makeSnpSelect,
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3
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mayRestrictAncestry
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} from "./chunk-T5BDYCFO.js";
|
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import "./chunk-7OYOC7XY.js";
|
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import {
|
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7
|
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addGeneSearchbox,
|
|
8
|
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filterInit,
|
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getNormalRoot
|
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} from "./chunk-EPGSHRD6.js";
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import "./chunk-HJ6L54YS.js";
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import "./chunk-ZZMWPGNS.js";
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import "./chunk-CXMZYVZT.js";
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import "./chunk-TF4BMI2M.js";
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import "./chunk-SSFOXHYJ.js";
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import "./chunk-FN5XPUPH.js";
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import "./chunk-LSEFWW72.js";
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import "./chunk-73VHTIHG.js";
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import "./chunk-IQIXGTQV.js";
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import "./chunk-UCLS2SVB.js";
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import "./chunk-MVTCBVSX.js";
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import "./chunk-EAHT56LQ.js";
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import "./chunk-5OHXYXLD.js";
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|
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import "./chunk-CTVZMQ5J.js";
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|
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-
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|
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|
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|
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|
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-
import "./chunk-OMR2DT66.js";
|
|
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|
-
import "./chunk-HFNDKYVF.js";
|
|
39
|
-
|
|
40
|
-
// termsetting/handlers/snplocus.ts
|
|
41
|
-
var term_name = "Variants in a locus";
|
|
42
|
-
function getHandler(self) {
|
|
43
|
-
return {
|
|
44
|
-
getPillName() {
|
|
45
|
-
return self.term.name;
|
|
46
|
-
},
|
|
47
|
-
getPillStatus() {
|
|
48
|
-
if (!self.term || !self.q) return;
|
|
49
|
-
if (!self.term.snps) throw `Missing term.snps [snplocs.ts getPillStatus()]`;
|
|
50
|
-
let text = `${self.q.chr}:${self.q.start}-${self.q.stop}, ${self.term.snps.length} variant${self.term.snps.length > 1 ? "s" : ""}`;
|
|
51
|
-
if (self.term.reachedVariantLimit) {
|
|
52
|
-
text += '<span style="margin-left: 6px; background:#aaa; font-size:1em;font-style: normal; border-radius: 7px;color:white;padding:0px 5px;">⚠<span>';
|
|
53
|
-
}
|
|
54
|
-
return { text };
|
|
55
|
-
},
|
|
56
|
-
validateQ(data) {
|
|
57
|
-
validateQ(data);
|
|
58
|
-
},
|
|
59
|
-
async showEditMenu(div) {
|
|
60
|
-
await makeEditMenu(self, div);
|
|
61
|
-
}
|
|
62
|
-
/* no need for postMain()
|
|
63
|
-
cache file contains all samples,
|
|
64
|
-
variants in a cache file is only determined by locus range and info fields
|
|
65
|
-
thus no need to regenerate cache file upon subcohort or filter change via pill.main()
|
|
66
|
-
async postMain() {
|
|
67
|
-
if (self.q && self.q.chr) {
|
|
68
|
-
await validateInput(self)
|
|
69
|
-
}
|
|
70
|
-
}
|
|
71
|
-
*/
|
|
72
|
-
};
|
|
73
|
-
}
|
|
74
|
-
async function makeEditMenu(self, div0) {
|
|
75
|
-
const div = div0.append("div").style("margin", "15px");
|
|
76
|
-
const select_ancestry = await mayRestrictAncestry(self, div);
|
|
77
|
-
const coordResult = addGeneSearchbox({
|
|
78
|
-
genome: self.opts.genomeObj,
|
|
79
|
-
tip: self.dom.tip2,
|
|
80
|
-
row: div.append("div").style("margin-top", "20px"),
|
|
81
|
-
defaultCoord: self.q && self.q.chr ? { chr: self.q.chr, start: self.q.start, stop: self.q.stop } : void 0
|
|
82
|
-
});
|
|
83
|
-
div.select(".sja_genesearchinput").style("margin", "0px");
|
|
84
|
-
div.append("span").style("margin", "5px 0px").style("display", "inline-block").style("opacity", 0.4).style("font-size", ".7em").html(
|
|
85
|
-
'"Gene": Gene name (e.g. AKT1)</br>"Position": chr:start-stop (e.g. chr1:5000-6000)</br>"dbSNP": dbSNP accession (e.g. rs1042522)'
|
|
86
|
-
);
|
|
87
|
-
await mayDisplayVariantFilter(self, self.q?.variant_filter, div);
|
|
88
|
-
const [input_AFcutoff, select_alleleType, select_geneticModel] = makeSnpSelect(
|
|
89
|
-
div.append("div").attr("class", "sjpp-snp-select").style("margin-top", "15px"),
|
|
90
|
-
self,
|
|
91
|
-
"snplocus"
|
|
92
|
-
);
|
|
93
|
-
if (self.usecase.target == "dataDownload") div.select(".sjpp-snp-select").style("display", "none");
|
|
94
|
-
const btnRow = div.append("div").style("margin-top", "15px");
|
|
95
|
-
btnRow.append("button").style("margin-top", "15px").text("Submit").on("click", async (event) => {
|
|
96
|
-
if (!coordResult.chr) return window.alert("Invalid coordinate");
|
|
97
|
-
event.target.disabled = true;
|
|
98
|
-
event.target.innerHTML = "Validating input...";
|
|
99
|
-
if (self.term) {
|
|
100
|
-
} else {
|
|
101
|
-
self.term = { id: makeId() };
|
|
102
|
-
}
|
|
103
|
-
if (!self.q) self.q = {};
|
|
104
|
-
self.term.type = "snplocus";
|
|
105
|
-
self.q.chr = coordResult.chr;
|
|
106
|
-
self.q.start = coordResult.start;
|
|
107
|
-
self.q.stop = coordResult.stop;
|
|
108
|
-
self.term.name = term_name;
|
|
109
|
-
delete self.term.snps;
|
|
110
|
-
self.q.variant_filter = getNormalRoot(self.variantFilter.active);
|
|
111
|
-
await validateInput(self);
|
|
112
|
-
{
|
|
113
|
-
const v = Number(input_AFcutoff.property("value"));
|
|
114
|
-
self.q.AFcutoff = v < 0 || v >= 100 ? 5 : v;
|
|
115
|
-
}
|
|
116
|
-
self.q.alleleType = select_alleleType.property("selectedIndex");
|
|
117
|
-
self.q.geneticModel = select_geneticModel.property("selectedIndex");
|
|
118
|
-
if (select_ancestry) {
|
|
119
|
-
self.q.restrictAncestry = select_ancestry.node().options[select_ancestry.property("selectedIndex")].__ancestry_obj;
|
|
120
|
-
}
|
|
121
|
-
self.api.runCallback();
|
|
122
|
-
});
|
|
123
|
-
btnRow.append("span").style("padding-left", "15px").style("opacity", 0.8).style("font-size", ".8em").text(
|
|
124
|
-
self.usecase.target == "dataDownload" ? "" : "Variants will be treated individually in separate regression models"
|
|
125
|
-
);
|
|
126
|
-
}
|
|
127
|
-
async function validateInput(self) {
|
|
128
|
-
const data = await self.vocabApi.validateSnps(self.q);
|
|
129
|
-
if (data.error) throw data.error;
|
|
130
|
-
self.q.cacheid = data.cacheid;
|
|
131
|
-
self.term.snps = data.snps;
|
|
132
|
-
self.term.reachedVariantLimit = data.reachedVariantLimit;
|
|
133
|
-
}
|
|
134
|
-
function validateQ(data) {
|
|
135
|
-
const q = data.q;
|
|
136
|
-
if (!Number.isFinite(q.AFcutoff)) throw "AFcutoff is not number";
|
|
137
|
-
if (q.AFcutoff < 0 || q.AFcutoff > 100) throw "AFcutoff is not within 0 to 100";
|
|
138
|
-
if (![0, 1].includes(q.alleleType)) throw "alleleType value is not one of 0/1";
|
|
139
|
-
if (![0, 1, 2, 3].includes(q.geneticModel)) throw "geneticModel value is not one of 0/1";
|
|
140
|
-
if (!q.chr) throw "chr missing";
|
|
141
|
-
if (!Number.isInteger(q.start)) throw "start coordinate is not integer";
|
|
142
|
-
if (!Number.isInteger(q.stop)) throw "stop coordinate is not integer";
|
|
143
|
-
if (q.start < 0) throw "start < 0";
|
|
144
|
-
if (q.stop <= q.start) throw "stop <= start";
|
|
145
|
-
}
|
|
146
|
-
async function fillTW(tw, vocabApi) {
|
|
147
|
-
try {
|
|
148
|
-
validateQ(tw);
|
|
149
|
-
} catch (e) {
|
|
150
|
-
throw "snplocus validateQ(): " + e;
|
|
151
|
-
}
|
|
152
|
-
if (!tw.term.name) tw.term.name = term_name;
|
|
153
|
-
if (tw.id == void 0 || tw.id == "") {
|
|
154
|
-
if (tw.term.id == void 0 || tw.term.id == "") {
|
|
155
|
-
tw.term.id = makeId();
|
|
156
|
-
}
|
|
157
|
-
tw.id = tw.term.id;
|
|
158
|
-
} else {
|
|
159
|
-
if (tw.term.id == void 0 || tw.term.id == "") {
|
|
160
|
-
tw.term.id = tw.id;
|
|
161
|
-
}
|
|
162
|
-
}
|
|
163
|
-
await validateInput({
|
|
164
|
-
term: tw.term,
|
|
165
|
-
q: tw.q,
|
|
166
|
-
vocabApi
|
|
167
|
-
});
|
|
168
|
-
}
|
|
169
|
-
function makeId() {
|
|
170
|
-
return "snplocus" + Math.random();
|
|
171
|
-
}
|
|
172
|
-
async function mayDisplayVariantFilter(self, filterInState, holder, callback2) {
|
|
173
|
-
if (!self.variantFilter) {
|
|
174
|
-
self.variantFilter = await self.vocabApi.get_variantFilter();
|
|
175
|
-
}
|
|
176
|
-
if (!self.variantFilter.terms) {
|
|
177
|
-
return;
|
|
178
|
-
}
|
|
179
|
-
if (!self.variantFilter.opts) throw "variantFilter.opts{} missing";
|
|
180
|
-
if (!self.variantFilter.filter) throw ".filter missing from variantFilter{}";
|
|
181
|
-
if (!Array.isArray(self.variantFilter.terms) || self.variantFilter.terms.length == 0)
|
|
182
|
-
throw "variantFilter.terms[] is not non-empty array";
|
|
183
|
-
if (filterInState) {
|
|
184
|
-
self.variantFilter.active = JSON.parse(JSON.stringify(filterInState));
|
|
185
|
-
} else {
|
|
186
|
-
self.variantFilter.active = JSON.parse(JSON.stringify(self.variantFilter.filter));
|
|
187
|
-
}
|
|
188
|
-
const div = holder.append("div").style("margin-top", "15px");
|
|
189
|
-
div.append("span").text("VARIANT FILTERS").style("font-size", ".8em").style("opacity", 0.5);
|
|
190
|
-
const filterBody = div.append("div");
|
|
191
|
-
filterInit({
|
|
192
|
-
joinWith: self.variantFilter.opts.joinWith,
|
|
193
|
-
emptyLabel: "+Variant Filter",
|
|
194
|
-
holder: filterBody,
|
|
195
|
-
vocab: { terms: self.variantFilter.terms },
|
|
196
|
-
callback: async (filter) => {
|
|
197
|
-
self.variantFilter.active = filter;
|
|
198
|
-
if (callback2) await callback2();
|
|
199
|
-
}
|
|
200
|
-
}).main(self.variantFilter.active);
|
|
201
|
-
}
|
|
202
|
-
export {
|
|
203
|
-
fillTW,
|
|
204
|
-
getHandler
|
|
205
|
-
};
|
|
206
|
-
//# sourceMappingURL=snplocus-PMAVBMTK.js.map
|
|
@@ -1,149 +0,0 @@
|
|
|
1
|
-
import {
|
|
2
|
-
font
|
|
3
|
-
} from "./chunk-EPGSHRD6.js";
|
|
4
|
-
import "./chunk-HJ6L54YS.js";
|
|
5
|
-
import "./chunk-ZZMWPGNS.js";
|
|
6
|
-
import "./chunk-CXMZYVZT.js";
|
|
7
|
-
import "./chunk-TF4BMI2M.js";
|
|
8
|
-
import "./chunk-SSFOXHYJ.js";
|
|
9
|
-
import "./chunk-FN5XPUPH.js";
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import "./chunk-UCLS2SVB.js";
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import "./chunk-MVTCBVSX.js";
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import "./chunk-5OHXYXLD.js";
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import "./chunk-O6TX37JQ.js";
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import "./chunk-W7MBUYQV.js";
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import "./chunk-MAR6R3H5.js";
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import "./chunk-IZ5H6KD4.js";
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import {
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IN_frame,
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exoncolor
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} from "./chunk-K535LGE2.js";
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import "./chunk-BEWDIM6H.js";
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import "./chunk-CTVZMQ5J.js";
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import "./chunk-LOZEKOES.js";
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import "./chunk-TOU7EVFQ.js";
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import "./chunk-733PDAIR.js";
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import "./chunk-SEEYV6P2.js";
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import "./chunk-NDWTN4U5.js";
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import "./chunk-OMR2DT66.js";
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import "./chunk-HFNDKYVF.js";
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// src/spliceevent.a53ss.diagram.js
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var junctionBcolor = "#990000";
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var color_truncateexon = "#00A352";
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function spliceevent_a53ss_diagram_default(arg) {
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const evt = arg.event;
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if (!evt) {
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arg.holder.text(".event missing");
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return;
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}
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if (evt.a5ss == void 0 && evt.a3ss == void 0) {
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arg.holder.text("not a5ss or a3ss");
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return;
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}
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const exonwidth = 30;
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const intronwidth = 30;
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const exonheight = 20;
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const distfontsize = exonheight - 5;
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const junctionheight = 20;
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const xpad = 30;
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const ypad = 20;
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const svg = arg.holder.append("svg");
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const g = svg.append("g").attr("transform", "translate(" + xpad + "," + ypad + ")");
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const distlabel = evt.sitedist + " nt";
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let distlabelw;
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g.append("text").text(distlabel).attr("font-size", distfontsize).attr("font-family", font).each(function() {
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distlabelw = this.getBBox().width;
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}).remove();
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const distlabelpad = 5;
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let leftinexon = false;
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let rightinexon = false;
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let leftinintron = false;
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let rightinintron = false;
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if (evt.a5ss) {
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if (evt.altinexon) leftinexon = true;
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else leftinintron = true;
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} else {
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if (evt.altinexon) rightinexon = true;
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else rightinintron = true;
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}
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let x = 0;
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let intronstart;
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let intronstop;
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g.append("rect").attr("fill", exoncolor).attr("stroke", exoncolor).attr("x", x).attr("y", junctionheight).attr("width", exonwidth).attr("height", exonheight).attr("shape-rendering", "crispEdges");
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g.append("text").text("e" + (evt.exon5idx + 1)).attr("text-anchor", "middle").attr("x", x + exonwidth / 2).attr("y", junctionheight + exonheight / 2).attr("fill", "white").attr("dominant-baseline", "central").attr("font-size", distfontsize).attr("font-family", font);
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x += exonwidth;
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if (leftinexon) {
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g.append("rect").attr("fill", color_truncateexon).attr("stroke", color_truncateexon).attr("x", x).attr("y", junctionheight).attr("width", distlabelw + distlabelpad * 2).attr("height", exonheight).attr("shape-rendering", "crispEdges");
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g.append("text").text(distlabel).attr("text-anchor", "middle").attr("x", x + distlabelw / 2 + distlabelpad).attr("y", junctionheight + exonheight / 2).attr("fill", "white").attr("dominant-baseline", "central").attr("font-size", distfontsize).attr("font-family", font);
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x += distlabelw + distlabelpad * 2;
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}
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intronstart = x;
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if (leftinintron || rightinintron) {
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if (leftinintron) {
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} else {
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x += intronwidth;
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}
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g.append("rect").attr("fill", "none").attr("stroke", exoncolor).attr("x", x).attr("y", junctionheight).attr("width", distlabelw + distlabelpad * 2).attr("height", exonheight).attr("shape-rendering", "crispEdges");
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g.append("text").text(distlabel).attr("text-anchor", "middle").attr("x", x + distlabelw / 2 + distlabelpad).attr("y", junctionheight + exonheight / 2).attr("font-size", distfontsize).attr("font-family", font).attr("dominant-baseline", "central");
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x += distlabelw + distlabelpad * 2;
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if (leftinintron) {
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x += intronwidth;
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}
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} else {
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x += intronwidth;
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100
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}
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intronstop = x;
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g.append("line").attr("x1", intronstart + (leftinintron ? distlabelw + distlabelpad * 2 : 0)).attr("y1", junctionheight + exonheight / 2).attr("x2", intronstop - (rightinintron ? distlabelw + distlabelpad * 2 : 0)).attr("y2", junctionheight + exonheight / 2).attr("stroke", exoncolor).attr("shape-rendering", "crispEdges");
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103
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if (rightinexon) {
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g.append("rect").attr("fill", color_truncateexon).attr("stroke", color_truncateexon).attr("x", x).attr("y", junctionheight).attr("width", distlabelw + distlabelpad * 2).attr("height", exonheight).attr("shape-rendering", "crispEdges");
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105
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g.append("text").text(distlabel).attr("text-anchor", "middle").attr("x", x + distlabelw / 2 + distlabelpad).attr("y", junctionheight + exonheight / 2).attr("fill", "white").attr("dominant-baseline", "central").attr("font-size", distfontsize).attr("font-family", font);
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x += distlabelw + distlabelpad * 2;
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107
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}
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108
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g.append("rect").attr("fill", exoncolor).attr("stroke", exoncolor).attr("x", x).attr("y", junctionheight).attr("width", exonwidth).attr("height", exonheight).attr("shape-rendering", "crispEdges");
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109
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g.append("text").text("e" + (evt.exon5idx + 1 + 1)).attr("text-anchor", "middle").attr("x", x + exonwidth / 2).attr("y", junctionheight + exonheight / 2).attr("fill", "white").attr("dominant-baseline", "central").attr("font-size", distfontsize).attr("font-family", font);
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110
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{
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|
111
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let x1, x2;
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112
|
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if (leftinexon || leftinintron) {
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113
|
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x2 = intronstop;
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114
|
-
if (leftinexon) {
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|
115
|
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x1 = intronstart - distlabelw - distlabelpad * 2;
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116
|
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} else {
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117
|
-
x1 = intronstart + distlabelw + distlabelpad * 2;
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|
118
|
-
}
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119
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-
} else {
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120
|
-
x1 = intronstart;
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121
|
-
if (rightinintron) {
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122
|
-
x2 = intronstop - distlabelw - distlabelpad * 2;
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123
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} else {
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124
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x2 = intronstop + distlabelw + distlabelpad * 2;
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125
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-
}
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126
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-
}
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127
|
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g.append("path").attr("d", "M" + x1 + "," + junctionheight + "L" + (x1 + x2) / 2 + ",0L" + x2 + "," + junctionheight).attr("stroke", junctionBcolor).attr("fill", "none");
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128
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g.append("text").text(evt.junctionB.v + (evt.frame != void 0 ? evt.frame == IN_frame ? ", in frame" : ",out of frame" : "")).attr("x", (x1 + x2) / 2).attr("y", -1).attr("text-anchor", "middle").attr("font-size", distfontsize).attr("fill", junctionBcolor);
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|
129
|
-
}
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|
130
|
-
let jAreadcounttext;
|
|
131
|
-
{
|
|
132
|
-
const line = g.append("path").attr(
|
|
133
|
-
"d",
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134
|
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"M" + intronstart + "," + (junctionheight + exonheight) + "L" + (intronstart + intronstop) / 2 + "," + (junctionheight * 2 + exonheight) + "L" + intronstop + "," + (junctionheight + exonheight)
|
|
135
|
-
).attr("stroke", exoncolor).attr("fill", "none");
|
|
136
|
-
const nj = evt.junctionA;
|
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137
|
-
if (nj) {
|
|
138
|
-
jAreadcounttext = g.append("text").text(nj.v).attr("x", (intronstart + intronstop) / 2).attr("y", junctionheight * 2 + exonheight + 1).attr("text-anchor", "middle").attr("font-size", distfontsize).attr("dominant-baseline", "hanging");
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|
139
|
-
} else {
|
|
140
|
-
line.attr("stroke-dasharray", "3,3");
|
|
141
|
-
}
|
|
142
|
-
}
|
|
143
|
-
svg.attr("width", xpad * 2 + exonwidth * 2 + intronwidth + distlabelw + distlabelpad * 2).attr("height", ypad * 2 + junctionheight * 2 + exonheight);
|
|
144
|
-
return jAreadcounttext;
|
|
145
|
-
}
|
|
146
|
-
export {
|
|
147
|
-
spliceevent_a53ss_diagram_default as default
|
|
148
|
-
};
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|
149
|
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//# sourceMappingURL=spliceevent.a53ss.diagram-G6W7EY3Q.js.map
|