@sjcrh/proteinpaint-client 2.166.0 → 2.167.1

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (882) hide show
  1. package/dist/2dmaf-6M6QWXAQ.js +1364 -0
  2. package/dist/AIProjectAdmin-2NHMC3IV.js +780 -0
  3. package/dist/AppHeader-CTHEWSZD.js +813 -0
  4. package/dist/BoxPlot-3U6ZAKKO.js +44 -0
  5. package/dist/CorrelationVolcano-2ASIR6KY.js +616 -0
  6. package/dist/DifferentialAnalysis-C3NYGF7U.js +237 -0
  7. package/dist/Disco-2QLBZ3X5.js +3089 -0
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  821. /package/dist/{plot.wsi-DJB7TDIS.js.map → plot.wsi-J5S4YYXN.js.map} +0 -0
  822. /package/dist/{polar-K5Z5FYKV.js.map → polar-LIJORXR6.js.map} +0 -0
  823. /package/dist/{profile.spec-A6EADWEC.js.map → profile.spec-3KE4CREI.js.map} +0 -0
  824. /package/dist/{profileBarchart-EFLPJK2P.js.map → profileBarchart-UQHOJB5V.js.map} +0 -0
  825. /package/dist/{profileForms-TG35YNLD.js.map → profileForms-WTYVTIUN.js.map} +0 -0
  826. /package/dist/{profilePlot-2EW2XVTK.js.map → profilePlot-SOXXEUAT.js.map} +0 -0
  827. /package/dist/{profileRadar-AKUYC2O5.js.map → profileRadar-2OHJ2RIU.js.map} +0 -0
  828. /package/dist/{profileRadarFacility-EAT66XTX.js.map → profileRadarFacility-GHLG3QNG.js.map} +0 -0
  829. /package/dist/{qualitative-PHQU5DXE.js.map → qualitative-B3OY7A7P.js.map} +0 -0
  830. /package/dist/{regression-EOMJRRDO.js.map → regression-HO2TO4XT.js.map} +0 -0
  831. /package/dist/{regression.inputs-LIH5X2JM.js.map → regression.inputs-JN3ZMIOP.js.map} +0 -0
  832. /package/dist/{regression.inputs.term-OO4RZ3QB.js.map → regression.inputs.term-67HVMXFZ.js.map} +0 -0
  833. /package/dist/{regression.inputs.values.table-E7WCTO2L.js.map → regression.inputs.values.table-JXJK2YZT.js.map} +0 -0
  834. /package/dist/{regression.integration.spec-62VEQP6X.js.map → regression.integration.spec-L54ZS5VY.js.map} +0 -0
  835. /package/dist/{regression.results-WAHFJ6NA.js.map → regression.results-3ZSFKUNN.js.map} +0 -0
  836. /package/dist/{regression.spec-IBIOTZVX.js.map → regression.spec-SVWCQX2U.js.map} +0 -0
  837. /package/dist/{report-MKDJXHGY.js.map → report-IHX7XSOI.js.map} +0 -0
  838. /package/dist/{runChart-ETM2EETF.js.map → runChart-QLQMK3OE.js.map} +0 -0
  839. /package/dist/{runchart.integration.spec-QFA4XBKB.js.map → runchart.integration.spec-5NVY5GHR.js.map} +0 -0
  840. /package/dist/{sampleScatter.spec-N4N7ZGZF.js.map → sampleScatter.spec-4Q5CQQWH.js.map} +0 -0
  841. /package/dist/{sampleView-JTY3RV7I.js.map → sampleView-7WHDFHB5.js.map} +0 -0
  842. /package/dist/{samplelst-RRUMBVT6.js.map → samplelst-34GJVLVD.js.map} +0 -0
  843. /package/dist/{samplematrix-L37O664Y.js.map → samplematrix-L2HOSLUT.js.map} +0 -0
  844. /package/dist/{scatter-E5QHW32W.js.map → scatter-X6AAM2LJ.js.map} +0 -0
  845. /package/dist/{scatter.integration.spec-FNVAJSVU.js.map → scatter.integration.spec-QSH3PLBK.js.map} +0 -0
  846. /package/dist/{selectGenomeWithTklst-J6VXCYGG.js.map → selectGenomeWithTklst-AJS2IPPW.js.map} +0 -0
  847. /package/dist/{singleCellPlot-S6S6CKYX.js.map → singleCellPlot-7JEWDVSR.js.map} +0 -0
  848. /package/dist/{singlecell-B4TNI23F.js.map → singlecell-IC5KU72L.js.map} +0 -0
  849. /package/dist/{singlecell-4BMIKFY4.js.map → singlecell-NWANPXWM.js.map} +0 -0
  850. /package/dist/{snp-PAUQ24NZ.js.map → snp-PSRNMTL6.js.map} +0 -0
  851. /package/dist/{snplocus-HVFYZTEE.js.map → snplocus-QCAVDYLR.js.map} +0 -0
  852. /package/dist/{spliceevent.a53ss.diagram-GGGHVNBF.js.map → spliceevent.a53ss.diagram-SGDJKUEC.js.map} +0 -0
  853. /package/dist/{spliceevent.exonskip.diagram-HLMFD6LJ.js.map → spliceevent.exonskip.diagram-BUYTHCK5.js.map} +0 -0
  854. /package/dist/{spliceevent.noeventdiagram-CKZ3BZ7Y.js.map → spliceevent.noeventdiagram-OJZJUHXP.js.map} +0 -0
  855. /package/dist/{ssGSEA-UGT4GH55.js.map → ssGSEA-UUZG57MF.js.map} +0 -0
  856. /package/dist/{stattable-6JWMALGB.js.map → stattable-324FS2HA.js.map} +0 -0
  857. /package/dist/{summarizeCnvGeneexp-BJOQY62E.js.map → summarizeCnvGeneexp-ZVZYWP43.js.map} +0 -0
  858. /package/dist/{summarizeGeneexpSurvival-4HDHL7PE.js.map → summarizeGeneexpSurvival-7XJRMT6M.js.map} +0 -0
  859. /package/dist/{summarizeMutationDiagnosis-TDWO5CKU.js.map → summarizeMutationDiagnosis-ZKLXOVY2.js.map} +0 -0
  860. /package/dist/{summarizeMutationSurvival-CJJFABOX.js.map → summarizeMutationSurvival-S4YPGLWA.js.map} +0 -0
  861. /package/dist/{summary-WOAXXIHG.js.map → summary-RVG7JL6Y.js.map} +0 -0
  862. /package/dist/{summary.integration.spec-GM73ERMN.js.map → summary.integration.spec-SCD35GO4.js.map} +0 -0
  863. /package/dist/{summaryInput-FD4SONTY.js.map → summaryInput-DMN6DTSW.js.map} +0 -0
  864. /package/dist/{sunburst-3LCJTBRN.js.map → sunburst-QZXYILRC.js.map} +0 -0
  865. /package/dist/{survival-A3A7IVXT.js.map → survival-6CWEBRSF.js.map} +0 -0
  866. /package/dist/{survival-XF72VMM6.js.map → survival-J657VYLI.js.map} +0 -0
  867. /package/dist/{survival.integration.spec-AU7MCAQV.js.map → survival.integration.spec-S5WE4V6M.js.map} +0 -0
  868. /package/dist/{svgraph-BEMS4JDJ.js.map → svgraph-NEKJL24M.js.map} +0 -0
  869. /package/dist/{svmr-CDEMTZPK.js.map → svmr-5RQ5JQF2.js.map} +0 -0
  870. /package/dist/{table-WYF6QCGB.js.map → table-CG6Z6NCJ.js.map} +0 -0
  871. /package/dist/{termCollection-BVQMNVY7.js.map → termCollection-FOQNVXB7.js.map} +0 -0
  872. /package/dist/{termInfo-JXLIVCSO.js.map → termInfo-5USFZGDB.js.map} +0 -0
  873. /package/dist/{tk-TGIIJYBO.js.map → tk-2O7XOVGJ.js.map} +0 -0
  874. /package/dist/{tp.ui-USYF67P7.js.map → tp.ui-S4YUVCZH.js.map} +0 -0
  875. /package/dist/{tvs.dtcnv.continuous-7SCTSFK3.js.map → tvs.dtcnv.continuous-7BPIXZ6C.js.map} +0 -0
  876. /package/dist/{tvs.numeric-OLVW6US3.js.map → tvs.numeric-FCC2EY62.js.map} +0 -0
  877. /package/dist/{tvs.samplelst-BHZHCX5V.js.map → tvs.samplelst-PKGFTULN.js.map} +0 -0
  878. /package/dist/{violin-OEOWVIZF.js.map → violin-C7IBRTYP.js.map} +0 -0
  879. /package/dist/{violin.integration.spec-AW2U3RHO.js.map → violin.integration.spec-WXRD3Z4E.js.map} +0 -0
  880. /package/dist/{violin.interactivity-3O2UDNPQ.js.map → violin.interactivity-BMG4TG5L.js.map} +0 -0
  881. /package/dist/{violin.renderer-W26FA6M7.js.map → violin.renderer-WUNW6ULV.js.map} +0 -0
  882. /package/dist/{vocabulary-BIQYDKVY.js.map → vocabulary-UUNEEBM3.js.map} +0 -0
@@ -1,714 +0,0 @@
1
- import {
2
- importPlot
3
- } from "./chunk-FOXJTDTH.js";
4
- import {
5
- PlotBase
6
- } from "./chunk-I2GCD26Y.js";
7
- import {
8
- GeneSetEditUI,
9
- digestMessage,
10
- newSandboxDiv,
11
- renderTable
12
- } from "./chunk-UT6W4ZZL.js";
13
- import "./chunk-HJ6L54YS.js";
14
- import {
15
- dofetch3
16
- } from "./chunk-5TDKRZN5.js";
17
- import "./chunk-RYRCMHYR.js";
18
- import "./chunk-ECKWM4HB.js";
19
- import {
20
- Menu
21
- } from "./chunk-NXOWHUR4.js";
22
- import "./chunk-5MWX5HUZ.js";
23
- import "./chunk-IQIXGTQV.js";
24
- import "./chunk-ICNJQHQZ.js";
25
- import {
26
- copyMerge,
27
- getCompInit
28
- } from "./chunk-FYTZCTJC.js";
29
- import "./chunk-7NTZWOJV.js";
30
- import "./chunk-OMO754MK.js";
31
- import "./chunk-RA5EXEHB.js";
32
- import "./chunk-PMZS3SHH.js";
33
- import "./chunk-LOZEKOES.js";
34
- import "./chunk-TOU7EVFQ.js";
35
- import "./chunk-W2IWHXLL.js";
36
- import "./chunk-5OHXYXLD.js";
37
- import "./chunk-UJUXE42U.js";
38
- import "./chunk-OMR2DT66.js";
39
- import "./chunk-NDWTN4U5.js";
40
- import "./chunk-HFNDKYVF.js";
41
-
42
- // plots/sc/model/SCModel.ts
43
- var SCModel = class {
44
- constructor(app, id) {
45
- this.app = app;
46
- this.id = id;
47
- this.state = this.app.getState();
48
- }
49
- /********** Single Cell SAMPLES for rendering the table *********/
50
- //The table data does not update
51
- //Should only need to init once
52
- async getSampleData() {
53
- const body = this.getSampleRequestOpts();
54
- return await dofetch3("termdb/singlecellSamples", { body });
55
- }
56
- //May involve more complicated logic later
57
- getSampleRequestOpts() {
58
- return {
59
- genome: this.state.vocab.genome,
60
- dslabel: this.state.vocab.dslabel,
61
- filter0: this.state.termfilter.filter0 || null
62
- };
63
- }
64
- //Fetches optional name for ds defined columns
65
- async getColumnLabels(dsScSamples) {
66
- if (!dsScSamples || !dsScSamples.sampleColumns) return;
67
- const colsCopy = structuredClone(dsScSamples.sampleColumns);
68
- for (const col of colsCopy) {
69
- let label = col.termid;
70
- try {
71
- label = (await this.app.vocabApi.getterm(col.termid)).name;
72
- } catch (e) {
73
- if (e.message) {
74
- }
75
- }
76
- col.label = label;
77
- }
78
- return colsCopy;
79
- }
80
- /********** Single Cell DATA for rendering plots *********/
81
- async getData() {
82
- const body = this.getDataRequestOpts();
83
- if (!body) return;
84
- return await dofetch3("termdb/singlecellData", { body });
85
- }
86
- getDataRequestOpts() {
87
- const state = this.app.getState();
88
- const singleCellTermdbConfig = state.termdbConfig?.queries?.singleCell;
89
- if (!singleCellTermdbConfig?.data) throw new Error("No singleCell.data defined in termdbConfig.queries");
90
- const config = state.plots.find((p) => p.id === this.id);
91
- if (!config.settings.sc.item) return;
92
- const plots = singleCellTermdbConfig.data.plots.map((p) => p.name);
93
- return {
94
- genome: this.state.vocab.genome,
95
- dslabel: this.state.vocab.dslabel,
96
- plots,
97
- sample: {
98
- eID: config.settings.sc.item.experiment,
99
- sID: config.settings.sc.item.sample
100
- }
101
- };
102
- }
103
- };
104
-
105
- // plots/sc/viewModel/SCViewModel.ts
106
- var SCViewModel = class {
107
- constructor(app, config, items, sampleColumns) {
108
- this.app = app;
109
- this.state = this.app.getState();
110
- const [rows, columns] = this.getTabelData(config, items, sampleColumns);
111
- const selectedRows = [];
112
- const i = items.findIndex((i2) => i2.sample == config.settings.sc.item?.sample);
113
- if (i != -1) selectedRows.push(i);
114
- this.tableData = {
115
- rows,
116
- columns,
117
- selectedRows
118
- };
119
- }
120
- getTabelData(plotConfig, items, sampleColumns) {
121
- const rows = [];
122
- const hasExperiments = items.some((i) => i.experiments);
123
- const columns = [{ label: plotConfig.settings.sc.columns.sample, sortable: true }];
124
- if (hasExperiments) columns.push({ label: "Sample", sortable: true });
125
- for (const col of sampleColumns || []) {
126
- columns.push({
127
- label: col.label,
128
- width: "14vw",
129
- sortable: true
130
- });
131
- }
132
- if (hasExperiments) columns.push({ label: "Experiment", sortable: true });
133
- for (const item of items) {
134
- if (hasExperiments)
135
- for (const exp of item.experiments) {
136
- const row = [{ value: item.sample, __experimentID: exp.experimentID }];
137
- row.push({ value: exp.sampleName });
138
- for (const col of sampleColumns || []) {
139
- row.push({ value: item[col.termid] });
140
- }
141
- if (this.state.vocab.dslabel == "GDC")
142
- row.push({ value: exp.experimentID, url: `https://portal.gdc.cancer.gov/files/${exp.experimentID}` });
143
- else row.push({ value: exp.experimentID });
144
- rows.push(row);
145
- }
146
- else {
147
- const row = [{ value: item.sample }];
148
- for (const col of sampleColumns || []) {
149
- row.push({ value: item[col.termid] });
150
- }
151
- rows.push(row);
152
- }
153
- }
154
- return [rows, columns];
155
- }
156
- };
157
-
158
- // plots/sc/interactions/SCInteractions.ts
159
- var SCInteractions = class {
160
- constructor(app, dom, id, getState) {
161
- this.app = app;
162
- this.dom = dom;
163
- this.id = id;
164
- this.getState = getState();
165
- }
166
- /** Used in the gene search menu shown on click from a plot btn
167
- * Add the plot to the state.plots array with .parentId. Adding
168
- * .parentId prevents the plot from launching in a new sandbox.
169
- * Pass the .parentId to both the plotConfig and the action.
170
- * this.getState() in SC.ts will find all the subplots with the parentId==this.id
171
- * SC.main() initializes the subplots as components in chartsDiv
172
- */
173
- async createSubplot(config) {
174
- const item = this.app.getState().plots.find((p) => p.id === this.id)?.settings.sc.item;
175
- await this.app.dispatch({
176
- type: "plot_create",
177
- parentId: this.id,
178
- config: Object.assign({}, config, { parentId: this.id, scItem: item })
179
- });
180
- }
181
- /** Updates the item in the plot settings */
182
- async updateItem(item) {
183
- await this.app.dispatch({
184
- type: "plot_edit",
185
- id: this.id,
186
- config: { settings: { sc: { item } } }
187
- });
188
- }
189
- toggleLoading(on) {
190
- if (on) {
191
- this.dom.loading.selectAll("*").remove();
192
- this.dom.loading.style("display", "block").append("div").style("position", "relative").style("top", "50%").append("span").attr("class", "sjpp-spinner");
193
- this.dom.loading.style("display", "");
194
- } else {
195
- this.dom.loading.selectAll(".sjpp-spinner").remove();
196
- this.dom.loading.style("display", "none");
197
- }
198
- }
199
- };
200
-
201
- // plots/sc/view/PlotSelectionRenderer.ts
202
- var PlotSelectionRenderer = class {
203
- constructor(dom, interactions, tableData) {
204
- this.dom = dom;
205
- this.interactions = interactions;
206
- this.renderSamplesTable(tableData);
207
- }
208
- /** Users select one item at a time to render the plot buttons
209
- * to init() plots in the dashboard.*/
210
- renderSamplesTable(tableData) {
211
- renderTable({
212
- rows: tableData.rows,
213
- columns: tableData.columns,
214
- div: this.dom.tableDiv,
215
- singleMode: true,
216
- maxWidth: tableData.columns.length > 3 ? "98vw" : "40vw",
217
- maxHeight: "30vh",
218
- header: {
219
- allowSort: true,
220
- style: { "text-transform": "capitalize" }
221
- },
222
- striped: true,
223
- selectedRows: tableData.selectedRows,
224
- noButtonCallback: (index) => {
225
- const item = {};
226
- tableData.rows[index].forEach((r, idx) => {
227
- if (!r.value) return;
228
- item[tableData.columns[idx].label.toLowerCase()] = r.value;
229
- });
230
- this.interactions.updateItem(item);
231
- this.dom.plotsBtnsDiv.style("display", "block");
232
- }
233
- });
234
- }
235
- };
236
-
237
- // plots/sc/view/PlotButtons.ts
238
- var PlotButtons = class {
239
- constructor(interactions, holder) {
240
- holder.style("padding", "10px");
241
- const promptDiv = holder.append("div").style("padding", "10px 0").text("Select data from");
242
- this.plotBtnsDom = {
243
- promptDiv,
244
- selectPrompt: promptDiv.append("span"),
245
- btnsDiv: holder.append("div"),
246
- tip: new Menu({ padding: "" })
247
- };
248
- this.interactions = interactions;
249
- const state = this.interactions.getState;
250
- this.scTermdbConfig = state.termdbConfig.queries.singleCell;
251
- }
252
- update(settings, data) {
253
- const item = settings.sc.item;
254
- this.plotBtnsDom.promptDiv.style("display", !item ? "none" : "block");
255
- if (!item) return;
256
- if (data != null && data.plots) this.data = data;
257
- this.settings = settings;
258
- this.item = item;
259
- const name = item.sample;
260
- this.plotBtnsDom.selectPrompt.text(` ${name}:`);
261
- this.renderChartBtns();
262
- }
263
- renderChartBtns() {
264
- this.plotBtnsDom.btnsDiv.selectAll("*").remove();
265
- const btns = this.getChartBtnOpts();
266
- this.plotBtnsDom.btnsDiv.selectAll("button").data(btns.filter((b) => b.isVisible())).enter().append("button").style("padding", "10px 15px").style("border-radius", "20px").style("border-color", "transparent").style("background-color", "#CFE2F3").style("margin", "0 10px").style("cursor", "pointer").text((b) => b.label).on("click", async (e, plot) => {
267
- if (plot.open) {
268
- this.plotBtnsDom.tip.clear().showunder(e.target);
269
- plot.open(plot, this);
270
- } else {
271
- const config = await plot.getPlotConfig();
272
- await this.interactions.createSubplot(config);
273
- }
274
- });
275
- }
276
- getChartBtnOpts() {
277
- const btns = [];
278
- for (const plots of this.scTermdbConfig?.data?.plots || []) {
279
- btns.push({
280
- label: plots.name,
281
- isVisible: () => true,
282
- getPlotConfig: async () => {
283
- return await this.getSingleCellConfig(plots.name);
284
- }
285
- });
286
- }
287
- btns.push(
288
- {
289
- label: "Gene expression",
290
- isVisible: () => true,
291
- open: this.geneSearchMenu,
292
- getPlotConfig: async (geneLst) => {
293
- if (!geneLst.length) {
294
- alert("No genes selected to launch gene expression subplot [PlotButtons.ts getChartBtnOpts()]");
295
- return;
296
- }
297
- if (geneLst.length == 1) return await this.getViolinConfig(geneLst[0].gene);
298
- else if (geneLst.length == 2) return await this.getScatterConfig(geneLst);
299
- else return this.getClusteringConfig(geneLst);
300
- }
301
- },
302
- {
303
- label: "Differential expression",
304
- isVisible: () => this.scTermdbConfig.DEgenes,
305
- open: this.termDropdownMenu,
306
- getPlotConfig: (value) => {
307
- return {
308
- chartType: "differentialAnalysis",
309
- termType: "singleCellCellType",
310
- //Eventually category will be updated to a term
311
- // term: {
312
- // name: term
313
- // },
314
- categoryName: `${value}`,
315
- termId: this.data.plots[0].colorBy || "Cluster",
316
- //CHANGEME
317
- sample: this.item.experiment || this.item.sample
318
- };
319
- }
320
- }
321
- );
322
- return btns;
323
- }
324
- //********** Btn Menus **********/
325
- geneSearchMenu(plot, self) {
326
- self.plotBtnsDom.tip.clear();
327
- new GeneSetEditUI({
328
- holder: self.plotBtnsDom.tip.d.append("div"),
329
- genome: self.interactions.app.opts.genome,
330
- vocabApi: {},
331
- callback: async (result) => {
332
- self.plotBtnsDom.tip.hide();
333
- const config = await plot.getPlotConfig(result.geneList);
334
- await self.interactions.createSubplot(config);
335
- }
336
- });
337
- }
338
- /** CHANGEME: This elem is a placeholder for now
339
- * Ideally this will call the tree with singleCellCellTerms.
340
- * That term type is not implemented yet. Once it is,
341
- * refactor this workflow to use the tree. */
342
- termDropdownMenu(plot, self) {
343
- self.plotBtnsDom.tip.clear();
344
- const _plot = self.data.plots[0];
345
- const wrapper = self.plotBtnsDom.tip.d.append("div").style("padding", "10px");
346
- wrapper.append("div").style("display", "block").style("width", "300px").text(`View differentially expressed genes of a ${_plot.colorBy.toLowerCase()} versus rest of the cells:`);
347
- const select = wrapper.append("select").style("margin", "10px 0").style("width", "auto").style("padding", "5px").on("change", async function() {
348
- self.plotBtnsDom.tip.hide();
349
- const value = select.node().value;
350
- if (value.indexOf("Select") == 0) return;
351
- const config = plot.getPlotConfig(value, _plot.colorBy);
352
- await self.interactions.createSubplot(config);
353
- });
354
- const regex = new RegExp(_plot.colorBy, "g");
355
- _plot.clusters.unshift(`Select ${_plot.colorBy}...`);
356
- for (const cluster of _plot.clusters) {
357
- select.append("option").attr("value", cluster.replace(regex, "").trim()).text(cluster);
358
- }
359
- }
360
- //********** Plot Config Helpers **********/
361
- async getViolinConfig(gene) {
362
- if (!this.item) throw new Error("No item selected");
363
- return {
364
- chartType: "violin",
365
- term: {
366
- $id: await digestMessage(`${gene}-${this.item.sample}-${this.item.experiment}`),
367
- term: {
368
- /** NOTE: There are no term handlers for the single cell types */
369
- type: "singleCellGeneExpression",
370
- id: gene,
371
- gene,
372
- name: gene,
373
- sample: {
374
- sID: this.item.sample,
375
- eID: this.item.experiment
376
- }
377
- }
378
- },
379
- term2: {
380
- //CHANGE ME
381
- $id: await digestMessage(`CHANGEME-${this.item.sample}-${this.item.experiment}`),
382
- term: {
383
- /** NOTE: There are no term handlers for the single cell types */
384
- type: "singleCellCellType",
385
- id: "cluster",
386
- //CHANGE ME, singlecell.data.plots.[i].colorColumns
387
- name: "cluster",
388
- //CHANGE ME
389
- sample: {
390
- sID: this.item.sample,
391
- eID: this.item.experiment
392
- },
393
- plot: "UMAP"
394
- //CHANGEME
395
- }
396
- }
397
- };
398
- }
399
- async getScatterConfig(geneLst) {
400
- if (!this.item) throw new Error("No item selected");
401
- const gene1 = geneLst[0].gene;
402
- const gene2 = geneLst[1].gene;
403
- return {
404
- chartType: "sampleScatter",
405
- term: {
406
- $id: await digestMessage(`${gene1}-${this.item.sample}-${this.item.experiment}`),
407
- term: {
408
- type: "singleCellGeneExpression",
409
- gene: gene1,
410
- id: gene1,
411
- name: gene1,
412
- sample: {
413
- sID: this.item.sample,
414
- eID: this.item.experiment
415
- }
416
- },
417
- q: { mode: "continuous" }
418
- },
419
- term2: {
420
- $id: await digestMessage(`${gene2}-${this.item.sample}-${this.item.experiment}`),
421
- term: {
422
- type: "singleCellGeneExpression",
423
- gene: gene2,
424
- id: gene2,
425
- name: gene2,
426
- sample: {
427
- sID: this.item.sample,
428
- eID: this.item.experiment
429
- }
430
- },
431
- q: { mode: "continuous" }
432
- }
433
- };
434
- }
435
- getClusteringConfig(geneLst) {
436
- if (!this.item) throw new Error("No item selected");
437
- const tws = geneLst.slice(0, 100).map((g) => {
438
- return {
439
- term: {
440
- gene: g.gene,
441
- name: `${g.gene} ${this.settings.hierCluster.unit}`,
442
- type: "singleCellGeneExpression",
443
- sample: this.item
444
- },
445
- q: {}
446
- };
447
- });
448
- return {
449
- chartType: "hierCluster",
450
- termgroups: [{ lst: tws, type: "hierCluster" }],
451
- dataType: "geneExpression",
452
- settings: { hierCluster: this.settings.hierCluster }
453
- };
454
- }
455
- async getSingleCellConfig(plotName) {
456
- if (!this.item) throw new Error("No item selected");
457
- const plot = this.scTermdbConfig.data.plots.find((p) => p.name == plotName);
458
- if (!plot) throw new Error(`No plot by name ${plotName} in data.plots [PlotButtons.ts getSingleCellConfig()]`);
459
- const cfg = {
460
- chartType: "sampleScatter",
461
- singleCellPlot: {
462
- name: plotName,
463
- sample: {
464
- sID: this.item.sample,
465
- eID: this.item.experiment
466
- }
467
- }
468
- };
469
- if (plot.colorColumns?.[0]) {
470
- cfg.colorTW = {
471
- $id: await digestMessage(`${plot.name}-${this.item.sample}-${this.item.experiment}`),
472
- term: {
473
- type: "singleCellCellType",
474
- name: plot.colorColumns[0].name,
475
- sample: {
476
- sID: this.item.sample,
477
- eID: this.item.experiment
478
- },
479
- plot: plotName
480
- }
481
- };
482
- }
483
- return cfg;
484
- }
485
- };
486
-
487
- // plots/sc/view/SCViewRenderer.ts
488
- var SCViewRenderer = class _SCViewRenderer {
489
- static {
490
- //On load, show table
491
- //Eventually maybe an app dispatch and not a flag
492
- this.inUse = true;
493
- }
494
- constructor(dom, interactions, segments) {
495
- this.dom = dom;
496
- this.interactions = interactions;
497
- this.plotBtns = new PlotButtons(this.interactions, this.dom.plotsBtnsDiv);
498
- this.segments = segments;
499
- }
500
- render(tableData) {
501
- this.renderSelectBtn();
502
- new PlotSelectionRenderer(this.dom, this.interactions, tableData);
503
- this.dom.plotsBtnsDiv.style("display", "none");
504
- }
505
- /** Renders the select btn at the top of the page that
506
- * show/hides the item table and plot buttons */
507
- renderSelectBtn() {
508
- this.dom.selectBtnDiv.style("padding", "10px");
509
- const btn = this.dom.selectBtnDiv.append("button").attr("data-testid", "sjpp-sc-item-table-select-btn").style("border-radius", "20px").style("padding", "5px 10px").style("background-color", "transparent").text("Select sample and plots");
510
- const arrowSpan = btn.append("span").style("font-size", "0.8em").style("padding-left", "3px").text("\u25BC");
511
- btn.on("click", () => {
512
- _SCViewRenderer.inUse = !_SCViewRenderer.inUse;
513
- arrowSpan.text(_SCViewRenderer.inUse ? "\u25BC" : "\u25B2");
514
- this.dom.tableDiv.style("display", _SCViewRenderer.inUse ? "block" : "none");
515
- this.dom.plotsBtnsDiv.style("display", _SCViewRenderer.inUse ? "block" : "none");
516
- });
517
- }
518
- update(settings, data) {
519
- this.plotBtns.update(settings, data);
520
- }
521
- removeSegments() {
522
- if (!Object.keys(this.segments).length) return;
523
- for (const [key, segment] of Object.entries(this.segments)) {
524
- const plots = segment.subplots.selectAll(".sjpp-output-sandbox-header").size();
525
- if (!plots) {
526
- segment.title.remove();
527
- segment.subplots.remove();
528
- delete this.segments[key];
529
- }
530
- }
531
- }
532
- };
533
-
534
- // plots/sc/defaults.ts
535
- function getDefaultSCAppSettings(overrides = {}, app) {
536
- const defaults = {
537
- sc: {
538
- columns: {
539
- // TODO: Implement ds specific column name
540
- sample: "Sample"
541
- },
542
- item: void 0
543
- },
544
- hierCluster: {
545
- unit: app.vocabApi.termdbConfig.queries.geneExpression?.unit || "Gene Expression",
546
- yDendrogramHeight: 0,
547
- clusterSamples: false
548
- }
549
- };
550
- return Object.assign(defaults, overrides);
551
- }
552
-
553
- // plots/sc/viewModel/plotData.ts
554
- function formatPlotData(_plots) {
555
- const plots = structuredClone(_plots);
556
- for (const plot of plots) {
557
- const expCells = plot.expCells.sort((a, b) => a.geneExp - b.geneExp);
558
- plot.cells = [...plot.noExpCells, ...expCells];
559
- const clusters = new Set(plot.cells.map((c) => c.category));
560
- plot.clusters = Array.from(clusters).sort((a, b) => {
561
- const num1 = parseInt(a.split(" ")[1]);
562
- const num2 = parseInt(b.split(" ")[1]);
563
- return num1 - num2;
564
- });
565
- }
566
- return plots;
567
- }
568
-
569
- // plots/sc/SC.ts
570
- var SCViewer = class extends PlotBase {
571
- constructor(opts, api) {
572
- super(opts, api);
573
- this.type = "sc";
574
- this.components = {
575
- plots: {}
576
- };
577
- const div = opts.holder.classed("sjpp-sc-main", true).append("div").style("padding", "5px").style("display", "inline-block").style("vertical-align", "top");
578
- this.dom = {
579
- div,
580
- loading: opts.holder.append("div").attr("class", "sjpp-sc-loading").style("position", "absolute").style("top", "0").style("left", "0").style("width", "100%").style("height", "100%").style("background-color", "rgba(255, 255, 255, 0.95)").style("text-align", "center"),
581
- selectBtnDiv: div.append("div").attr("id", "sjpp-sc-select-btn"),
582
- tableDiv: div.append("div").attr("id", "sjpp-sc-item-table"),
583
- plotsBtnsDiv: div.append("div").attr("id", "sjpp-sc-plot-buttons").style("display", "none")
584
- };
585
- this.segments = {};
586
- if (opts.header) opts.header.html(`SINGLE CELL`).style("font-size", "0.9em");
587
- }
588
- getState(appState) {
589
- const config = appState.plots.find((p) => p.id === this.id);
590
- if (!config) {
591
- throw new Error(
592
- `No plot with id='${this.id}' found. Did you set this.id before this.api = getComponentApi(this)?`
593
- );
594
- }
595
- return {
596
- config,
597
- subplots: appState.plots.filter((p) => p.parentId === this.id),
598
- termfilter: appState.termfilter,
599
- termdbConfig: appState.termdbConfig,
600
- vocab: appState.vocab
601
- };
602
- }
603
- async init(appState) {
604
- const state = this.getState(appState);
605
- const dsScSamples = state.termdbConfig.queries?.singleCell?.samples;
606
- this.model = new SCModel(this.app, this.id);
607
- try {
608
- const response = await this.model.getSampleData();
609
- if (response.error || !response.samples || !response.samples.length) {
610
- this.app.printError("No samples found for this dataset");
611
- return;
612
- }
613
- this.items = response.samples;
614
- this.itemColumns = await this.model.getColumnLabels(dsScSamples);
615
- } catch (e) {
616
- if (e instanceof Error) console.error(`${e.message || e} [SC init()]`);
617
- else if (e.stack) console.log(e.stack);
618
- throw new Error(e.message || e);
619
- }
620
- this.interactions = new SCInteractions(this.app, this.dom, this.id, () => this.getState(this.app.getState()));
621
- this.viewModel = new SCViewModel(this.app, state.config, this.items, this.itemColumns);
622
- this.view = new SCViewRenderer(this.dom, this.interactions, this.segments);
623
- this.view.render(this.viewModel.tableData);
624
- }
625
- //TODO: .text() should be ds specific
626
- async initSegment(item) {
627
- const caseText = item.case ? `Case: ${item.case}` : "";
628
- const itemText = item.sample ? `Sample: ${item.sample}` : "";
629
- const projectText = item["project id"] ? `Project: ${item["project id"]}` : "";
630
- const headerText = [itemText, caseText, projectText].join(" ");
631
- this.segments[item.sample] = {
632
- title: this.dom.div.append("div").style("margin-left", "10px").style("padding", "10px").style("font-weight", 600).text(headerText),
633
- subplots: this.dom.div.append("div").style("margin-left", "10px")
634
- };
635
- }
636
- /** The plot obj is already in state.plots[] but not rendered
637
- * (see SCInteractions). This creates the component and renders the plot */
638
- async initSubplotComponent(subplot) {
639
- const sandbox = newSandboxDiv(this.segments[subplot.scItem.sample].subplots, {
640
- close: () => {
641
- delete this.components.plots[subplot.id];
642
- this.app.dispatch({
643
- type: "plot_delete",
644
- id: subplot.id,
645
- parentId: this.id
646
- });
647
- this.view?.removeSegments();
648
- },
649
- plotId: subplot.id,
650
- // beforePlotId: plot.insertBefore || null,
651
- style: {
652
- //TODO: What width is appropriate here? 50%?
653
- width: "98.5%"
654
- }
655
- });
656
- const opts = Object.assign({}, subplot, {
657
- app: this.app,
658
- holder: sandbox.body,
659
- header: sandbox.header,
660
- parentId: this.id,
661
- id: subplot.id
662
- });
663
- const { componentInit: componentInit2 } = await importPlot(opts.chartType);
664
- this.components.plots[subplot.id] = await componentInit2(opts);
665
- }
666
- async main() {
667
- const state = this.getState(this.app.getState());
668
- const config = state.config;
669
- if (!this.model) throw new Error(`Model not initialized`);
670
- if (!this.viewModel) throw new Error(`ViewModel not initialized`);
671
- if (!this.view) throw new Error(`View not initialized`);
672
- if (!this.interactions) throw new Error(`Interactions not initialized`);
673
- this.interactions.toggleLoading(true);
674
- for (const subplot of state.subplots) {
675
- if (!this.segments[subplot.scItem.sample]) this.initSegment(subplot.scItem);
676
- if (!this.components.plots[subplot.id]) await this.initSubplotComponent(subplot);
677
- }
678
- let data = null;
679
- if (config.settings.sc.item) {
680
- try {
681
- data = await this.model.getData();
682
- if (data.error || !data.plots || !data.plots.length) {
683
- this.interactions.toggleLoading(false);
684
- this.app.printError(data.error);
685
- return;
686
- }
687
- } catch (e) {
688
- this.interactions.toggleLoading(false);
689
- if (e instanceof Error) console.error(`${e.message || e} [SC main()]`);
690
- else if (e.stack) console.log(e.stack);
691
- throw new Error(e.message || e);
692
- }
693
- data.plots = formatPlotData(data.plots);
694
- }
695
- this.view.update(config.settings, data);
696
- this.interactions.toggleLoading(false);
697
- }
698
- };
699
- var SCInit = getCompInit(SCViewer);
700
- var componentInit = SCInit;
701
- function getPlotConfig(opts, app) {
702
- const config = {
703
- chartType: "sc",
704
- hidePlotFilter: true,
705
- settings: getDefaultSCAppSettings(opts.overrides, app)
706
- };
707
- return copyMerge(config, opts);
708
- }
709
- export {
710
- SCInit,
711
- componentInit,
712
- getPlotConfig
713
- };
714
- //# sourceMappingURL=SC-Z4KBNK7P.js.map