@precisa-saude/fhir 0.37.2 → 0.38.1

package/dist/cli.js

@@ -461,6 +461,22 @@ var BIOMARKER_DEFINITIONS = [
     },
     unit: "pg/mL"
   },
+  {
+    category: "tireoide",
+    code: "T3Total",
+    // 3053-6 é "Triiodothyronine (T3) [Mass/volume] in Serum or Plasma", o T3
+    // total, conferido no fhir.loinc.org em out/2026. O catálogo só tinha o
+    // livre (3051-0), e o SUS fatura o T3 num código só (SIGTAP 0202060390,
+    // "Dosagem de triiodotironina"), que é o total (fhir-brasil#132). Os nomes
+    // seguem os do `T4Total`. Sem faixa por enquanto: nenhuma fonte conferida
+    // publica o intervalo do T3 total para adultos aqui.
+    loinc: "3053-6",
+    names: {
+      en: ["Triiodothyronine", "T3 Total", "Total T3", "Triiodothyronine (T3)"],
+      pt: ["Triiodotironina", "T3 Total", "Triiodotironina Total", "Triiodotironina (T3)"]
+    },
+    unit: "ng/dL"
+  },
   {
     category: "tireoide",
     code: "T4Total",
@@ -1449,7 +1465,12 @@ var BIOMARKER_DEFINITIONS = [
     code: "TotalProtein",
     loinc: "2885-2",
     names: {
-      en: ["Total Protein", "Serum Protein"],
+      // "Protein, Total" é a grafia da Quest, no formato "EXAME, QUALIFICADOR".
+      // A troca de vírgula do pré-scan não basta aqui: dobrada, a linha vira
+      // "protein total", que não é nome do catálogo, e sobrava o "Protein"
+      // solto, sinônimo de `Protein_Urine`. A proteína do soro ancorava como
+      // proteína da urina. Com a grafia literal, o nome longo engole o curto.
+      en: ["Total Protein", "Serum Protein", "Protein, Total"],
       pt: ["Prote\xEDna Total", "Prote\xEDnas Totais"]
     },
     unit: "g/dL"
@@ -1713,6 +1734,28 @@ var BIOMARKER_DEFINITIONS = [
     },
     unit: "mg/dL"
   },
+  {
+    // 3094-0 é "Urea nitrogen [Mass/volume] in Serum or Plasma", o BUN que o
+    // laudo americano imprime ("UREA NITROGEN (BUN)" na Quest). É outro
+    // componente que `Urea` (3091-6): o BUN conta só o nitrogênio da molécula,
+    // e ureia ≈ BUN × 2,14. Por isso os nomes de BUN saíram de `Urea` na
+    // issue #41, e voltam aqui, numa entrada própria. Sem a entrada, o "urea"
+    // de dentro de "UREA NITROGEN" ancorava a ureia, e o valor de BUN era lido
+    // contra a faixa de 15-50 mg/dL da ureia.
+    //
+    // Faixa (out/2026): 5 a 20 mg/dL, de Hosten, "BUN and Creatinine",
+    // Clinical Methods, 3. ed., cap. 193: "The normal range of urea nitrogen in
+    // blood or serum is 5 to 20 mg/dl, or 1.8 to 7.1 mmol urea per liter." O
+    // capítulo não publica intervalo ótimo, e a faixa fica sem um.
+    category: "rins",
+    code: "BUN",
+    loinc: "3094-0",
+    names: {
+      en: ["Urea Nitrogen (BUN)", "Urea Nitrogen", "BUN"],
+      pt: ["Nitrog\xEAnio Ureico"]
+    },
+    unit: "mg/dL"
+  },
   {
     category: "rins",
     code: "BUN_Creatinine_Ratio",
@@ -4703,6 +4746,21 @@ var LOINC_SNAPSHOT = {
       system: "Ser/Plas",
       time: "Pt"
     },
+    "3053-6": {
+      component: "Triiodothyronine",
+      display: "Triiodothyronine (T3) [Mass/volume] in Serum or Plasma",
+      groups: {
+        "LG11953-3": "Triiodothyronine|MCnc|Pt|ANYBldSerPl",
+        "LG49720-2": "Triiodothyronine|Pt|Ser/Plas|650.977 g/mole",
+        "LG51986-4": "Triiodothyronine|Pt|ANYBldSerPl|650.977 g/mole"
+      },
+      method: null,
+      property: "MCnc",
+      scale: "Qn",
+      status: "ACTIVE",
+      system: "Ser/Plas",
+      time: "Pt"
+    },
     "3084-1": {
       component: "Urate",
       display: "Urate [Mass/volume] in Serum or Plasma",
@@ -4746,6 +4804,20 @@ var LOINC_SNAPSHOT = {
       system: "Ser/Plas",
       time: "Pt"
     },
+    "3094-0": {
+      component: "Urea nitrogen",
+      display: "Urea nitrogen [Mass/volume] in Serum or Plasma",
+      groups: {
+        "LG1314-6": "Urea nitrogen|MCnc|Pt|ANYBldSerPl",
+        "LG49763-2": "Urea nitrogen|Pt|Ser/Plas"
+      },
+      method: null,
+      property: "MCnc",
+      scale: "Qn",
+      status: "ACTIVE",
+      system: "Ser/Plas",
+      time: "Pt"
+    },
     "3097-3": {
       component: "Urea nitrogen/Creatinine",
       display: "Urea nitrogen/Creatinine [Mass Ratio] in Serum or Plasma",
@@ -6372,6 +6444,17 @@ var BIOMARKER_UNITS = {
     siUcum: "pg/mL",
     siUnit: "pg/mL"
   },
+  // O BUN em mmol/L é expresso como ureia: cada molécula de ureia tem dois
+  // nitrogênios, então a massa que entra na conversão é a de N2 (2 × 14,007),
+  // e não a da ureia (60,06) usada em `Urea`. 14 mg/dL de BUN ≈ 5 mmol/L.
+  BUN: {
+    aliases: { "mg/dl": "mg/dL", "mmol/l": "mmol/L" },
+    canonicalUcum: "mg/dL",
+    canonicalUnit: "mg/dL",
+    molecularWeight: 28.0134,
+    siUcum: "mmol/L",
+    siUnit: "mmol/L"
+  },
   CA125: {
     aliases: { "u/ml": "U/mL" },
     canonicalUcum: "U/mL",
@@ -6812,6 +6895,14 @@ var BIOMARKER_UNITS = {
     siUcum: "pmol/L",
     siUnit: "pmol/L"
   },
+  T3Total: {
+    aliases: { "ng/dl": "ng/dL", "nmol/l": "nmol/L" },
+    canonicalUcum: "ng/dL",
+    canonicalUnit: "ng/dL",
+    molecularWeight: 650.98,
+    siUcum: "nmol/L",
+    siUnit: "nmol/L"
+  },
   T4Free: {
     aliases: { "ng/dl": "ng/dL", "pmol/l": "pmol/L" },
     canonicalUcum: "ng/dL",
@@ -7223,6 +7314,15 @@ var biomarkerRangeDefinitions = {
     kind: "reference-interval",
     source: "tietz-7ed-2015"
   },
+  // BUN (nitrogênio ureico): "The normal range of urea nitrogen in blood or
+  // serum is 5 to 20 mg/dl" (Hosten, Clinical Methods, cap. 193). O capítulo
+  // não publica intervalo ótimo nem partição por sexo ou idade; a queda na
+  // gestação (5 a 7 mg/dL) aparece como contexto, não como intervalo próprio.
+  BUN: {
+    default: { max: 20, min: 5, unit: "mg/dL" },
+    kind: "reference-interval",
+    source: "hosten-clinical-methods-1990"
+  },
   CA125: {
     default: { max: 35, min: 0, optimalMax: 25, optimalMin: 0, unit: "U/mL" },
     kind: "reference-interval",
@@ -9682,6 +9782,18 @@ var MAPPING_DECISIONS = {
   BNP: nameOnly("30934-4"),
   BodyFatPct: nameOnly("41982-0"),
   BodyWaterPct: nameOnly("101684-9"),
+  BUN: {
+    loinc: "3094-0",
+    evidence: ["name", "unit"],
+    settledBy: "name",
+    note: 'criado em out/2026 para o BUN dos laudos americanos (Quest imprime "UREA NITROGEN (BUN)" em mg/dL); a ureia dos laudos brasileiros segue em Urea',
+    siblingsRejected: [
+      {
+        loinc: "3091-6",
+        reason: "ureia: outro componente (a mol\xE9cula inteira, n\xE3o s\xF3 o nitrog\xEAnio), valor cerca de 2,14 vezes maior que o BUN"
+      }
+    ]
+  },
   BUN_Creatinine_Ratio: nameOnly("3097-3"),
   C3: nameOnly("4485-9"),
   C4: nameOnly("4498-2"),
@@ -9922,6 +10034,13 @@ var MAPPING_DECISIONS = {
   SpecificGravity_Urine: nameOnly("5811-5"),
   SquamousEpithelial_Urine: nameOnly("11277-1"),
   T3Free: nameOnly("3051-0"),
+  T3Total: {
+    evidence: ["name", "unit"],
+    loinc: "3053-6",
+    note: "T3 total em massa/volume; o livre \xE9 o 3051-0. Pedido no fhir-brasil#132.",
+    settledBy: "name",
+    siblingsRejected: []
+  },
   T4Free: nameOnly("3024-7"),
   T4Total: nameOnly("3026-2"),
   Testosterone: nameOnly("2986-8"),
@@ -10684,6 +10803,13 @@ var SOURCE_REGISTRY = {
   // ---------------------------------------------------------------------------
   // Referência laboratorial geral
   // ---------------------------------------------------------------------------
+  // Capítulo de livro no NCBI Bookshelf (PMID 21250147). A URL é a do texto
+  // completo, onde está o intervalo citado na faixa do BUN.
+  "hosten-clinical-methods-1990": {
+    abnt: "HOSTEN, A. O. BUN and creatinine. In: WALKER, H. K.; HALL, W. D.; HURST, J. W. (ed.). Clinical Methods: the history, physical, and laboratory examinations. 3. ed. Boston: Butterworths, 1990. cap. 193.",
+    key: "hosten-clinical-methods-1990",
+    url: "https://www.ncbi.nlm.nih.gov/books/NBK305/"
+  },
   "kalaria-ck-ri-2026": {
     abnt: "KALARIA, T. et al. Age, sex and ethnicity changes in creatine kinase and sex- and ethnicity-specific reference intervals of creatine kinase. Clinical Medicine, v. 26, n. 4, p. 100596, 2026.",
     doi: "10.1016/j.clinme.2026.100596",
@@ -11068,7 +11194,7 @@ var COMMANDS = {
 async function main() {
   const { command, help, json, resto, version } = dividirArgv(process.argv.slice(2));
   if (version) {
-    process.stdout.write(`${"0.37.2"}
+    process.stdout.write(`${"0.38.1"}
 `);
     return;
   }

package/dist/converter.cjs

@@ -3,15 +3,15 @@
 
 
 
-var _chunk3YB2ORY7cjs = require('./chunk-3YB2ORY7.cjs');
+var _chunk46PNS7KWcjs = require('./chunk-46PNS7KW.cjs');
 require('./chunk-OR67NJDZ.cjs');
-require('./chunk-DE7NHXIR.cjs');
-require('./chunk-RWUFK5AN.cjs');
-require('./chunk-BDS6CM7F.cjs');
+require('./chunk-4O3QE7DU.cjs');
+require('./chunk-IY6BZX2V.cjs');
+require('./chunk-VMID6CDC.cjs');
 
 
 
 
 
-exports.labObservationToFHIR = _chunk3YB2ORY7cjs.labObservationToFHIR; exports.labReportToFHIR = _chunk3YB2ORY7cjs.labReportToFHIR; exports.labResultToFHIRBundle = _chunk3YB2ORY7cjs.labResultToFHIRBundle; exports.userProfileToFHIR = _chunk3YB2ORY7cjs.userProfileToFHIR;
+exports.labObservationToFHIR = _chunk46PNS7KWcjs.labObservationToFHIR; exports.labReportToFHIR = _chunk46PNS7KWcjs.labReportToFHIR; exports.labResultToFHIRBundle = _chunk46PNS7KWcjs.labResultToFHIRBundle; exports.userProfileToFHIR = _chunk46PNS7KWcjs.userProfileToFHIR;
 //# sourceMappingURL=converter.cjs.map

package/dist/converter.js

@@ -3,11 +3,11 @@ import {
   labReportToFHIR,
   labResultToFHIRBundle,
   userProfileToFHIR
-} from "./chunk-JMWPX43H.js";
+} from "./chunk-X2BYLSNK.js";
 import "./chunk-A6HR4XDK.js";
-import "./chunk-O7SK2YUU.js";
-import "./chunk-CZLX33DZ.js";
-import "./chunk-YCJUGK6D.js";
+import "./chunk-SIXIWFC5.js";
+import "./chunk-2J3V7DCF.js";
+import "./chunk-XVXLDN4Q.js";
 export {
   labObservationToFHIR,
   labReportToFHIR,

package/dist/importer.cjs

@@ -4,16 +4,16 @@
 
 
 
-var _chunkAJUDODBTcjs = require('./chunk-AJUDODBT.cjs');
-require('./chunk-LSC7NHFE.cjs');
+var _chunkLUGMRMWYcjs = require('./chunk-LUGMRMWY.cjs');
+require('./chunk-NUFN24W4.cjs');
 require('./chunk-OR67NJDZ.cjs');
-require('./chunk-RWUFK5AN.cjs');
-require('./chunk-BDS6CM7F.cjs');
+require('./chunk-IY6BZX2V.cjs');
+require('./chunk-VMID6CDC.cjs');
 
 
 
 
 
 
-exports.MAX_FILE_SIZE = _chunkAJUDODBTcjs.MAX_FILE_SIZE; exports.MAX_OBSERVATIONS = _chunkAJUDODBTcjs.MAX_OBSERVATIONS; exports.extractObservationsFromBundle = _chunkAJUDODBTcjs.extractObservationsFromBundle; exports.mapFHIRObservationToInternal = _chunkAJUDODBTcjs.mapFHIRObservationToInternal; exports.processImportBundle = _chunkAJUDODBTcjs.processImportBundle;
+exports.MAX_FILE_SIZE = _chunkLUGMRMWYcjs.MAX_FILE_SIZE; exports.MAX_OBSERVATIONS = _chunkLUGMRMWYcjs.MAX_OBSERVATIONS; exports.extractObservationsFromBundle = _chunkLUGMRMWYcjs.extractObservationsFromBundle; exports.mapFHIRObservationToInternal = _chunkLUGMRMWYcjs.mapFHIRObservationToInternal; exports.processImportBundle = _chunkLUGMRMWYcjs.processImportBundle;
 //# sourceMappingURL=importer.cjs.map

package/dist/importer.js

@@ -4,11 +4,11 @@ import {
   extractObservationsFromBundle,
   mapFHIRObservationToInternal,
   processImportBundle
-} from "./chunk-VOBVUACD.js";
-import "./chunk-CVMOQDM2.js";
+} from "./chunk-77N3LQNM.js";
+import "./chunk-GG3MOT3C.js";
 import "./chunk-A6HR4XDK.js";
-import "./chunk-CZLX33DZ.js";
-import "./chunk-YCJUGK6D.js";
+import "./chunk-2J3V7DCF.js";
+import "./chunk-XVXLDN4Q.js";
 export {
   MAX_FILE_SIZE,
   MAX_OBSERVATIONS,

package/dist/index.cjs

@@ -7,19 +7,19 @@
 
 
 
-var _chunk3YB2ORY7cjs = require('./chunk-3YB2ORY7.cjs');
+var _chunk46PNS7KWcjs = require('./chunk-46PNS7KW.cjs');
 
 
 
 
 
 
-var _chunkAJUDODBTcjs = require('./chunk-AJUDODBT.cjs');
+var _chunkLUGMRMWYcjs = require('./chunk-LUGMRMWY.cjs');
 
 
 
 
-var _chunkLSC7NHFEcjs = require('./chunk-LSC7NHFE.cjs');
+var _chunkNUFN24W4cjs = require('./chunk-NUFN24W4.cjs');
 
 
 
@@ -33,11 +33,11 @@ var _chunkOR67NJDZcjs = require('./chunk-OR67NJDZ.cjs');
 
 
 
-var _chunkDE7NHXIRcjs = require('./chunk-DE7NHXIR.cjs');
+var _chunk4O3QE7DUcjs = require('./chunk-4O3QE7DU.cjs');
 
 
 
-var _chunk5FMR2U7Pcjs = require('./chunk-5FMR2U7P.cjs');
+var _chunkC3SMDNLCcjs = require('./chunk-C3SMDNLC.cjs');
 
 
 
@@ -49,7 +49,7 @@ var _chunk5FMR2U7Pcjs = require('./chunk-5FMR2U7P.cjs');
 
 
 
-var _chunkRWUFK5ANcjs = require('./chunk-RWUFK5AN.cjs');
+var _chunkIY6BZX2Vcjs = require('./chunk-IY6BZX2V.cjs');
 
 
 
@@ -83,7 +83,7 @@ var _chunkRWUFK5ANcjs = require('./chunk-RWUFK5AN.cjs');
 
 
 
-var _chunkBDS6CM7Fcjs = require('./chunk-BDS6CM7F.cjs');
+var _chunkVMID6CDCcjs = require('./chunk-VMID6CDC.cjs');
 
 // src/category-groups.ts
 var CATEGORY_GROUPS = {
@@ -245,14 +245,14 @@ function interventionToFHIRObservation(intervention, patientId) {
 }
 function interventionsToFHIRBundle(interventions, userProfile) {
   const patientId = userProfile.userId;
-  const fhirPatient = _chunk3YB2ORY7cjs.userProfileToFHIR.call(void 0, userProfile);
+  const fhirPatient = _chunk46PNS7KWcjs.userProfileToFHIR.call(void 0, userProfile);
   const entries = interventions.map((intervention) => {
     const isMedication = intervention.type === "medication" || intervention.type === "supplement";
     const resource = isMedication ? interventionToFHIRMedicationStatement(intervention, patientId) : interventionToFHIRObservation(intervention, patientId);
-    return { fullUrl: _chunk3YB2ORY7cjs.entryFullUrl.call(void 0, resource), resource };
+    return { fullUrl: _chunk46PNS7KWcjs.entryFullUrl.call(void 0, resource), resource };
   });
   return {
-    entry: [{ fullUrl: _chunk3YB2ORY7cjs.entryFullUrl.call(void 0, fhirPatient), resource: fhirPatient }, ...entries],
+    entry: [{ fullUrl: _chunk46PNS7KWcjs.entryFullUrl.call(void 0, fhirPatient), resource: fhirPatient }, ...entries],
     resourceType: "Bundle",
     type: "collection"
   };
@@ -714,6 +714,18 @@ var MAPPING_DECISIONS = {
   BNP: nameOnly("30934-4"),
   BodyFatPct: nameOnly("41982-0"),
   BodyWaterPct: nameOnly("101684-9"),
+  BUN: {
+    loinc: "3094-0",
+    evidence: ["name", "unit"],
+    settledBy: "name",
+    note: 'criado em out/2026 para o BUN dos laudos americanos (Quest imprime "UREA NITROGEN (BUN)" em mg/dL); a ureia dos laudos brasileiros segue em Urea',
+    siblingsRejected: [
+      {
+        loinc: "3091-6",
+        reason: "ureia: outro componente (a mol\xE9cula inteira, n\xE3o s\xF3 o nitrog\xEAnio), valor cerca de 2,14 vezes maior que o BUN"
+      }
+    ]
+  },
   BUN_Creatinine_Ratio: nameOnly("3097-3"),
   C3: nameOnly("4485-9"),
   C4: nameOnly("4498-2"),
@@ -954,6 +966,13 @@ var MAPPING_DECISIONS = {
   SpecificGravity_Urine: nameOnly("5811-5"),
   SquamousEpithelial_Urine: nameOnly("11277-1"),
   T3Free: nameOnly("3051-0"),
+  T3Total: {
+    evidence: ["name", "unit"],
+    loinc: "3053-6",
+    note: "T3 total em massa/volume; o livre \xE9 o 3051-0. Pedido no fhir-brasil#132.",
+    settledBy: "name",
+    siblingsRejected: []
+  },
   T4Free: nameOnly("3024-7"),
   T4Total: nameOnly("3026-2"),
   Testosterone: nameOnly("2986-8"),
@@ -1171,16 +1190,16 @@ function getNoLoincDecision(code) {
 
 // src/mapping-sheet.ts
 function getMappingSheet(codeOrLoinc) {
-  const def = _nullishCoalesce(_chunkBDS6CM7Fcjs.getDefinitionByCode.call(void 0, codeOrLoinc), () => ( _chunkBDS6CM7Fcjs.getDefinitionByLoinc.call(void 0, codeOrLoinc)));
+  const def = _nullishCoalesce(_chunkVMID6CDCcjs.getDefinitionByCode.call(void 0, codeOrLoinc), () => ( _chunkVMID6CDCcjs.getDefinitionByLoinc.call(void 0, codeOrLoinc)));
   if (!def) return void 0;
   const decision = getMappingDecision(def.code);
-  const chosen = def.loinc ? _chunk3YB2ORY7cjs.getLoincEntry.call(void 0, def.loinc) : void 0;
+  const chosen = def.loinc ? _chunk46PNS7KWcjs.getLoincEntry.call(void 0, def.loinc) : void 0;
   const candidates = [];
   if (def.loinc) candidates.push({ axes: chosen, loinc: def.loinc, role: "chosen" });
   for (const v of _nullishCoalesce(def.methodVariants, () => ( []))) {
     const cues = [...v.cues.pt, ...v.cues.en];
     candidates.push({
-      axes: _chunk3YB2ORY7cjs.getLoincEntry.call(void 0, v.loinc),
+      axes: _chunk46PNS7KWcjs.getLoincEntry.call(void 0, v.loinc),
       loinc: v.loinc,
       role: "method-variant",
       why: cues.length ? cues.join("; ") : void 0
@@ -1188,7 +1207,7 @@ function getMappingSheet(codeOrLoinc) {
   }
   for (const s of _nullishCoalesce(_optionalChain([decision, 'optionalAccess', _ => _.siblingsRejected]), () => ( []))) {
     candidates.push({
-      axes: _chunk3YB2ORY7cjs.getLoincEntry.call(void 0, s.loinc),
+      axes: _chunk46PNS7KWcjs.getLoincEntry.call(void 0, s.loinc),
       loinc: s.loinc,
       role: "rejected",
       why: s.reason
@@ -1232,7 +1251,7 @@ function specimenClassOf(material) {
   return CLASSE_DO_MATERIAL[primeiraPalavra(material)];
 }
 function loincSpecimenClass(loinc) {
-  const system = _optionalChain([_chunk3YB2ORY7cjs.getLoincEntry.call(void 0, loinc), 'optionalAccess', _5 => _5.system]);
+  const system = _optionalChain([_chunk46PNS7KWcjs.getLoincEntry.call(void 0, loinc), 'optionalAccess', _5 => _5.system]);
   return system ? CLASSE_DO_SISTEMA[system] : void 0;
 }
 function specimenMismatch(material, loinc) {
@@ -1244,7 +1263,7 @@ function specimenMismatch(material, loinc) {
     loinc,
     material: doMaterial,
     reason: "specimen-mismatch",
-    system: _nullishCoalesce(_optionalChain([_chunk3YB2ORY7cjs.getLoincEntry.call(void 0, loinc), 'optionalAccess', _6 => _6.system]), () => ( ""))
+    system: _nullishCoalesce(_optionalChain([_chunk46PNS7KWcjs.getLoincEntry.call(void 0, loinc), 'optionalAccess', _6 => _6.system]), () => ( ""))
   };
 }
 
@@ -1358,5 +1377,5 @@ function specimenMismatch(material, loinc) {
 
 
 
-exports.AGE_BRACKETS = AGE_BRACKETS; exports.BIOMARKER_CODE_SYSTEM = _chunkOR67NJDZcjs.BIOMARKER_CODE_SYSTEM; exports.BIOMARKER_DEFAULT_UNIT = _chunkRWUFK5ANcjs.BIOMARKER_DEFAULT_UNIT; exports.BIOMARKER_DEFINITIONS = _chunkBDS6CM7Fcjs.BIOMARKER_DEFINITIONS; exports.BIOMARKER_UNITS = _chunkRWUFK5ANcjs.BIOMARKER_UNITS; exports.BODY_FAT_ZONES = BODY_FAT_ZONES; exports.BR_TIPO_AMOSTRA_VALUESET = BR_TIPO_AMOSTRA_VALUESET; exports.BUNDLE_BASE_URL = _chunk3YB2ORY7cjs.BUNDLE_BASE_URL; exports.CAC_INDICATOR_CODES = _chunkBDS6CM7Fcjs.CAC_INDICATOR_CODES; exports.CATEGORY_GROUPS = CATEGORY_GROUPS; exports.CATEGORY_SCREENING_INTERVALS = CATEGORY_SCREENING_INTERVALS; exports.DEXA_CATEGORIES = _chunkBDS6CM7Fcjs.DEXA_CATEGORIES; exports.DEXA_INDICATOR_CODES = _chunkBDS6CM7Fcjs.DEXA_INDICATOR_CODES; exports.FHIR_BRASIL_EXTENSIONS = FHIR_BRASIL_EXTENSIONS; exports.HL7_SPECIMEN_TYPE_SYSTEM = HL7_SPECIMEN_TYPE_SYSTEM; exports.IG_CANONICAL = IG_CANONICAL; exports.LOINC_SNAPSHOT = _chunk3YB2ORY7cjs.LOINC_SNAPSHOT; exports.LOINC_SYSTEM = _chunkOR67NJDZcjs.LOINC_SYSTEM; exports.MAPPING_DECISIONS = MAPPING_DECISIONS; exports.MAX_FILE_SIZE = _chunkAJUDODBTcjs.MAX_FILE_SIZE; exports.MAX_OBSERVATIONS = _chunkAJUDODBTcjs.MAX_OBSERVATIONS; exports.NO_LOINC_DECISIONS = NO_LOINC_DECISIONS; exports.SOURCE_REGISTRY = _chunk5FMR2U7Pcjs.SOURCE_REGISTRY; exports.T_SCORE_ZONES = T_SCORE_ZONES; exports.UNIT_TO_UCUM = _chunkRWUFK5ANcjs.UNIT_TO_UCUM; exports.ZONE_DEFS = ZONE_DEFS; exports.applyFallbackReferenceRanges = _chunkDE7NHXIRcjs.applyFallbackReferenceRanges; exports.biomarkerRangeDefinitions = _chunkDE7NHXIRcjs.biomarkerRangeDefinitions; exports.calculateNextScreeningDate = calculateNextScreeningDate; exports.cnsToFHIRIdentifier = cnsToFHIRIdentifier; exports.codeToLoinc = _chunkBDS6CM7Fcjs.codeToLoinc; exports.convertUnit = _chunkRWUFK5ANcjs.convertUnit; exports.cpfToFHIRIdentifier = cpfToFHIRIdentifier; exports.defaultReferenceRanges = _chunkDE7NHXIRcjs.defaultReferenceRanges; exports.entryFullUrl = _chunk3YB2ORY7cjs.entryFullUrl; exports.extractObservationsFromBundle = _chunkAJUDODBTcjs.extractObservationsFromBundle; exports.extractSourceKey = _chunk5FMR2U7Pcjs.extractSourceKey; exports.filterVisibleBiomarkers = _chunkBDS6CM7Fcjs.filterVisibleBiomarkers; exports.findCodeByName = _chunkBDS6CM7Fcjs.findCodeByName; exports.flagAgainstCatalogRange = _chunkDE7NHXIRcjs.flagAgainstCatalogRange; exports.formatCNS = formatCNS; exports.formatCPF = formatCPF; exports.generateCacFullReference = _chunkBDS6CM7Fcjs.generateCacFullReference; exports.generateDexaFullReference = _chunkBDS6CM7Fcjs.generateDexaFullReference; exports.generateFilteredLLMReference = _chunkBDS6CM7Fcjs.generateFilteredLLMReference; exports.generateLLMReference = _chunkBDS6CM7Fcjs.generateLLMReference; exports.getAllCodes = _chunkBDS6CM7Fcjs.getAllCodes; exports.getAllDefinitions = _chunkBDS6CM7Fcjs.getAllDefinitions; exports.getAllLoincCodes = _chunkBDS6CM7Fcjs.getAllLoincCodes; exports.getAllSearchPatterns = _chunkBDS6CM7Fcjs.getAllSearchPatterns; exports.getBiomarkersByCategory = _chunkBDS6CM7Fcjs.getBiomarkersByCategory; exports.getBiomarkersForCategories = _chunkBDS6CM7Fcjs.getBiomarkersForCategories; exports.getCanonicalUnit = _chunkRWUFK5ANcjs.getCanonicalUnit; exports.getCategoriesByInterval = getCategoriesByInterval; exports.getCategoryGroup = getCategoryGroup; exports.getDaysUntilScreening = getDaysUntilScreening; exports.getDefaultUnit = _chunkRWUFK5ANcjs.getDefaultUnit; exports.getDefinitionByCode = _chunkBDS6CM7Fcjs.getDefinitionByCode; exports.getDefinitionByLoinc = _chunkBDS6CM7Fcjs.getDefinitionByLoinc; exports.getDefinitionsBySex = _chunkBDS6CM7Fcjs.getDefinitionsBySex; exports.getDueCategories = getDueCategories; exports.getFallbackReferenceRange = _chunkDE7NHXIRcjs.getFallbackReferenceRange; exports.getLoincEntry = _chunk3YB2ORY7cjs.getLoincEntry; exports.getMappingDecision = getMappingDecision; exports.getMappingSheet = getMappingSheet; exports.getNoLoincDecision = getNoLoincDecision; exports.getRangeDirection = _chunkDE7NHXIRcjs.getRangeDirection; exports.getReferenceRange = _chunkDE7NHXIRcjs.getReferenceRange; exports.getSIUnit = _chunkRWUFK5ANcjs.getSIUnit; exports.getScreeningInterval = getScreeningInterval; exports.getSexForCode = _chunkBDS6CM7Fcjs.getSexForCode; exports.getVisibleDefinitions = _chunkBDS6CM7Fcjs.getVisibleDefinitions; exports.interventionToFHIRMedicationStatement = interventionToFHIRMedicationStatement; exports.interventionToFHIRObservation = interventionToFHIRObservation; exports.interventionsToFHIRBundle = interventionsToFHIRBundle; exports.isBiomarkerVisible = _chunkBDS6CM7Fcjs.isBiomarkerVisible; exports.isCacDocument = _chunkBDS6CM7Fcjs.isCacDocument; exports.isDexaDocument = _chunkBDS6CM7Fcjs.isDexaDocument; exports.isScreeningDue = isScreeningDue; exports.isUcumCode = _chunkRWUFK5ANcjs.isUcumCode; exports.isValidCode = _chunkBDS6CM7Fcjs.isValidCode; exports.isValidLoinc = _chunkBDS6CM7Fcjs.isValidLoinc; exports.labObservationToFHIR = _chunk3YB2ORY7cjs.labObservationToFHIR; exports.labReportToFHIR = _chunk3YB2ORY7cjs.labReportToFHIR; exports.labResultToFHIRBundle = _chunk3YB2ORY7cjs.labResultToFHIRBundle; exports.listMappedSubcategories = listMappedSubcategories; exports.loincSpecimenClass = loincSpecimenClass; exports.loincToCode = _chunkBDS6CM7Fcjs.loincToCode; exports.mapFHIRObservationToInternal = _chunkAJUDODBTcjs.mapFHIRObservationToInternal; exports.methodVariantOf = _chunkBDS6CM7Fcjs.methodVariantOf; exports.normalizeCode = _chunkBDS6CM7Fcjs.normalizeCode; exports.plural = plural; exports.pluralCount = pluralCount; exports.pluralPhrase = pluralPhrase; exports.pluralPhraseCount = pluralPhraseCount; exports.processImportBundle = _chunkAJUDODBTcjs.processImportBundle; exports.referenceRangeMeaning = _chunkDE7NHXIRcjs.referenceRangeMeaning; exports.resolveUcum = _chunkRWUFK5ANcjs.resolveUcum; exports.specimenClassOf = specimenClassOf; exports.specimenMismatch = specimenMismatch; exports.specimenTypeCoding = specimenTypeCoding; exports.toBiomarkerTests = _chunkBDS6CM7Fcjs.toBiomarkerTests; exports.unitToUCUM = _chunkRWUFK5ANcjs.unitToUCUM; exports.userProfileToFHIR = _chunk3YB2ORY7cjs.userProfileToFHIR; exports.validateCNS = validateCNS; exports.validateCPF = validateCPF; exports.validateFHIRDiagnosticReport = _chunkLSC7NHFEcjs.validateFHIRDiagnosticReport; exports.validateFHIRImportBundle = _chunkLSC7NHFEcjs.validateFHIRImportBundle; exports.validateFHIRObservation = _chunkLSC7NHFEcjs.validateFHIRObservation; exports.validateLoincNameMatch = _chunkBDS6CM7Fcjs.validateLoincNameMatch;
+exports.AGE_BRACKETS = AGE_BRACKETS; exports.BIOMARKER_CODE_SYSTEM = _chunkOR67NJDZcjs.BIOMARKER_CODE_SYSTEM; exports.BIOMARKER_DEFAULT_UNIT = _chunkIY6BZX2Vcjs.BIOMARKER_DEFAULT_UNIT; exports.BIOMARKER_DEFINITIONS = _chunkVMID6CDCcjs.BIOMARKER_DEFINITIONS; exports.BIOMARKER_UNITS = _chunkIY6BZX2Vcjs.BIOMARKER_UNITS; exports.BODY_FAT_ZONES = BODY_FAT_ZONES; exports.BR_TIPO_AMOSTRA_VALUESET = BR_TIPO_AMOSTRA_VALUESET; exports.BUNDLE_BASE_URL = _chunk46PNS7KWcjs.BUNDLE_BASE_URL; exports.CAC_INDICATOR_CODES = _chunkVMID6CDCcjs.CAC_INDICATOR_CODES; exports.CATEGORY_GROUPS = CATEGORY_GROUPS; exports.CATEGORY_SCREENING_INTERVALS = CATEGORY_SCREENING_INTERVALS; exports.DEXA_CATEGORIES = _chunkVMID6CDCcjs.DEXA_CATEGORIES; exports.DEXA_INDICATOR_CODES = _chunkVMID6CDCcjs.DEXA_INDICATOR_CODES; exports.FHIR_BRASIL_EXTENSIONS = FHIR_BRASIL_EXTENSIONS; exports.HL7_SPECIMEN_TYPE_SYSTEM = HL7_SPECIMEN_TYPE_SYSTEM; exports.IG_CANONICAL = IG_CANONICAL; exports.LOINC_SNAPSHOT = _chunk46PNS7KWcjs.LOINC_SNAPSHOT; exports.LOINC_SYSTEM = _chunkOR67NJDZcjs.LOINC_SYSTEM; exports.MAPPING_DECISIONS = MAPPING_DECISIONS; exports.MAX_FILE_SIZE = _chunkLUGMRMWYcjs.MAX_FILE_SIZE; exports.MAX_OBSERVATIONS = _chunkLUGMRMWYcjs.MAX_OBSERVATIONS; exports.NO_LOINC_DECISIONS = NO_LOINC_DECISIONS; exports.SOURCE_REGISTRY = _chunkC3SMDNLCcjs.SOURCE_REGISTRY; exports.T_SCORE_ZONES = T_SCORE_ZONES; exports.UNIT_TO_UCUM = _chunkIY6BZX2Vcjs.UNIT_TO_UCUM; exports.ZONE_DEFS = ZONE_DEFS; exports.applyFallbackReferenceRanges = _chunk4O3QE7DUcjs.applyFallbackReferenceRanges; exports.biomarkerRangeDefinitions = _chunk4O3QE7DUcjs.biomarkerRangeDefinitions; exports.calculateNextScreeningDate = calculateNextScreeningDate; exports.cnsToFHIRIdentifier = cnsToFHIRIdentifier; exports.codeToLoinc = _chunkVMID6CDCcjs.codeToLoinc; exports.convertUnit = _chunkIY6BZX2Vcjs.convertUnit; exports.cpfToFHIRIdentifier = cpfToFHIRIdentifier; exports.defaultReferenceRanges = _chunk4O3QE7DUcjs.defaultReferenceRanges; exports.entryFullUrl = _chunk46PNS7KWcjs.entryFullUrl; exports.extractObservationsFromBundle = _chunkLUGMRMWYcjs.extractObservationsFromBundle; exports.extractSourceKey = _chunkC3SMDNLCcjs.extractSourceKey; exports.filterVisibleBiomarkers = _chunkVMID6CDCcjs.filterVisibleBiomarkers; exports.findCodeByName = _chunkVMID6CDCcjs.findCodeByName; exports.flagAgainstCatalogRange = _chunk4O3QE7DUcjs.flagAgainstCatalogRange; exports.formatCNS = formatCNS; exports.formatCPF = formatCPF; exports.generateCacFullReference = _chunkVMID6CDCcjs.generateCacFullReference; exports.generateDexaFullReference = _chunkVMID6CDCcjs.generateDexaFullReference; exports.generateFilteredLLMReference = _chunkVMID6CDCcjs.generateFilteredLLMReference; exports.generateLLMReference = _chunkVMID6CDCcjs.generateLLMReference; exports.getAllCodes = _chunkVMID6CDCcjs.getAllCodes; exports.getAllDefinitions = _chunkVMID6CDCcjs.getAllDefinitions; exports.getAllLoincCodes = _chunkVMID6CDCcjs.getAllLoincCodes; exports.getAllSearchPatterns = _chunkVMID6CDCcjs.getAllSearchPatterns; exports.getBiomarkersByCategory = _chunkVMID6CDCcjs.getBiomarkersByCategory; exports.getBiomarkersForCategories = _chunkVMID6CDCcjs.getBiomarkersForCategories; exports.getCanonicalUnit = _chunkIY6BZX2Vcjs.getCanonicalUnit; exports.getCategoriesByInterval = getCategoriesByInterval; exports.getCategoryGroup = getCategoryGroup; exports.getDaysUntilScreening = getDaysUntilScreening; exports.getDefaultUnit = _chunkIY6BZX2Vcjs.getDefaultUnit; exports.getDefinitionByCode = _chunkVMID6CDCcjs.getDefinitionByCode; exports.getDefinitionByLoinc = _chunkVMID6CDCcjs.getDefinitionByLoinc; exports.getDefinitionsBySex = _chunkVMID6CDCcjs.getDefinitionsBySex; exports.getDueCategories = getDueCategories; exports.getFallbackReferenceRange = _chunk4O3QE7DUcjs.getFallbackReferenceRange; exports.getLoincEntry = _chunk46PNS7KWcjs.getLoincEntry; exports.getMappingDecision = getMappingDecision; exports.getMappingSheet = getMappingSheet; exports.getNoLoincDecision = getNoLoincDecision; exports.getRangeDirection = _chunk4O3QE7DUcjs.getRangeDirection; exports.getReferenceRange = _chunk4O3QE7DUcjs.getReferenceRange; exports.getSIUnit = _chunkIY6BZX2Vcjs.getSIUnit; exports.getScreeningInterval = getScreeningInterval; exports.getSexForCode = _chunkVMID6CDCcjs.getSexForCode; exports.getVisibleDefinitions = _chunkVMID6CDCcjs.getVisibleDefinitions; exports.interventionToFHIRMedicationStatement = interventionToFHIRMedicationStatement; exports.interventionToFHIRObservation = interventionToFHIRObservation; exports.interventionsToFHIRBundle = interventionsToFHIRBundle; exports.isBiomarkerVisible = _chunkVMID6CDCcjs.isBiomarkerVisible; exports.isCacDocument = _chunkVMID6CDCcjs.isCacDocument; exports.isDexaDocument = _chunkVMID6CDCcjs.isDexaDocument; exports.isScreeningDue = isScreeningDue; exports.isUcumCode = _chunkIY6BZX2Vcjs.isUcumCode; exports.isValidCode = _chunkVMID6CDCcjs.isValidCode; exports.isValidLoinc = _chunkVMID6CDCcjs.isValidLoinc; exports.labObservationToFHIR = _chunk46PNS7KWcjs.labObservationToFHIR; exports.labReportToFHIR = _chunk46PNS7KWcjs.labReportToFHIR; exports.labResultToFHIRBundle = _chunk46PNS7KWcjs.labResultToFHIRBundle; exports.listMappedSubcategories = listMappedSubcategories; exports.loincSpecimenClass = loincSpecimenClass; exports.loincToCode = _chunkVMID6CDCcjs.loincToCode; exports.mapFHIRObservationToInternal = _chunkLUGMRMWYcjs.mapFHIRObservationToInternal; exports.methodVariantOf = _chunkVMID6CDCcjs.methodVariantOf; exports.normalizeCode = _chunkVMID6CDCcjs.normalizeCode; exports.plural = plural; exports.pluralCount = pluralCount; exports.pluralPhrase = pluralPhrase; exports.pluralPhraseCount = pluralPhraseCount; exports.processImportBundle = _chunkLUGMRMWYcjs.processImportBundle; exports.referenceRangeMeaning = _chunk4O3QE7DUcjs.referenceRangeMeaning; exports.resolveUcum = _chunkIY6BZX2Vcjs.resolveUcum; exports.specimenClassOf = specimenClassOf; exports.specimenMismatch = specimenMismatch; exports.specimenTypeCoding = specimenTypeCoding; exports.toBiomarkerTests = _chunkVMID6CDCcjs.toBiomarkerTests; exports.unitToUCUM = _chunkIY6BZX2Vcjs.unitToUCUM; exports.userProfileToFHIR = _chunk46PNS7KWcjs.userProfileToFHIR; exports.validateCNS = validateCNS; exports.validateCPF = validateCPF; exports.validateFHIRDiagnosticReport = _chunkNUFN24W4cjs.validateFHIRDiagnosticReport; exports.validateFHIRImportBundle = _chunkNUFN24W4cjs.validateFHIRImportBundle; exports.validateFHIRObservation = _chunkNUFN24W4cjs.validateFHIRObservation; exports.validateLoincNameMatch = _chunkVMID6CDCcjs.validateLoincNameMatch;
 //# sourceMappingURL=index.cjs.map