@precisa-saude/fhir 0.31.5 → 0.32.0

package/dist/cli.js

@@ -1,8 +1,5 @@
 #!/usr/bin/env node
 
-// src/cli/index.ts
-import { parseArgs as parseArgs3 } from "util";
-
 // src/cli-utils.ts
 async function readStdin() {
   if (process.stdin.isTTY) return "";
@@ -52,6 +49,23 @@ function exitWithError(message, code = 1) {
   process.exit(code);
 }
 
+// src/cli/argv.ts
+function dividirArgv(argv) {
+  let command;
+  let help = false;
+  let json = false;
+  let version = false;
+  const resto = [];
+  for (const token of argv) {
+    if (token === "--json") json = true;
+    else if (token === "--help" || token === "-h") help = true;
+    else if (token === "--version" || token === "-v") version = true;
+    else if (command === void 0 && !token.startsWith("-")) command = token;
+    else resto.push(token);
+  }
+  return { command, help, json, resto, version };
+}
+
 // src/biomarkers.ts
 var BIOMARKER_DEFINITIONS = [
   // ============================================================================
@@ -2144,7 +2158,14 @@ var BIOMARKER_DEFINITIONS = [
         "Fat Percentage",
         "Percent Body Fat",
         "% Body Fat",
-        "Total Body % Fat"
+        "Total Body % Fat",
+        // A Live Lean imprime "Total Fat %" na tabela regional da página 1 (a
+        // linha "Total" é o percentual do corpo inteiro) e "Total Fat (%)" na
+        // tabela de tendência. Os dois são o "Total Body Fat %" da mesma data.
+        // Sem eles, o "Total Fat" da massa de gordura, logo abaixo, ancorava
+        // `FatMass` na citação do percentual.
+        "Total Fat %",
+        "Total Fat (%)"
       ],
       pt: [
         "Percentual de Gordura Corporal",
@@ -2162,7 +2183,10 @@ var BIOMARKER_DEFINITIONS = [
     code: "FatMass",
     loinc: "73708-0",
     names: {
-      en: ["Fat Mass", "Total Fat Mass", "Body Fat Mass", "Fat Tissue Mass"],
+      // "Total Fat" é a coluna "Total Fat (lbs)" da tabela de tendência da
+      // densitometria Live Lean, e traz o mesmo número do "Fat Mass" da página
+      // 1 em todas as datas que as duas tabelas imprimem.
+      en: ["Fat Mass", "Total Fat Mass", "Body Fat Mass", "Fat Tissue Mass", "Total Fat"],
       pt: ["Massa de Gordura", "Massa Gorda", "Massa de Gordura Total", "Tecido Adiposo"]
     },
     unit: "kg"
@@ -2182,7 +2206,18 @@ var BIOMARKER_DEFINITIONS = [
     category: "composicao-corporal",
     code: "LeanMass",
     names: {
-      en: ["Lean Mass", "Lean Body Mass", "Lean Tissue Mass", "Total Lean Mass", "LBM"],
+      // "Total Lean" é a coluna "Total Lean (lbs)" da mesma tabela de
+      // tendência: tecido magro, igual ao "Lean Mass" da página 1, e não a
+      // massa livre de gordura, que soma o mineral ósseo e fica em
+      // `FatFreeMass`.
+      en: [
+        "Lean Mass",
+        "Lean Body Mass",
+        "Lean Tissue Mass",
+        "Total Lean Mass",
+        "LBM",
+        "Total Lean"
+      ],
       pt: ["Massa Magra", "Massa Corporal Magra", "Tecido Magro", "Massa Magra Total"]
     },
     unit: "kg"
@@ -6744,6 +6779,403 @@ async function range(args, json) {
   );
 }
 
+// src/cli/commands/source.ts
+import { parseArgs as parseArgs3 } from "util";
+
+// src/sources.ts
+var SOURCE_REGISTRY = {
+  // ---------------------------------------------------------------------------
+  // Fontes internacionais — Cardiovascular
+  // ---------------------------------------------------------------------------
+  "agatston-1990": {
+    abnt: "AGATSTON, A. S. et al. Quantification of coronary artery calcium using ultrafast computed tomography. Journal of the American College of Cardiology, v. 15, n. 4, p. 827-832, 1990.",
+    doi: "10.1016/0735-1097(90)90282-T",
+    key: "agatston-1990",
+    url: "https://pubmed.ncbi.nlm.nih.gov/2407762/"
+  },
+  "browning-ashwell-2010": {
+    abnt: "BROWNING, L. M.; HSIEH, S. D.; ASHWELL, M. A systematic review of waist-to-height ratio as a screening tool for the prediction of cardiovascular disease and diabetes: 0,5 could be a suitable global boundary value. Nutrition Research Reviews, v. 23, n. 2, p. 247-269, 2010.",
+    doi: "10.1017/S0954422410000144",
+    key: "browning-ashwell-2010",
+    url: "https://pubmed.ncbi.nlm.nih.gov/20819243/"
+  },
+  "castelli-ratio-1992": {
+    abnt: "CASTELLI, W. P. et al. Lipids and risk of coronary heart disease: the Framingham Study. Annals of Epidemiology, v. 2, n. 1-2, p. 23-28, 1992.",
+    doi: "10.1016/1047-2797(92)90033-M",
+    key: "castelli-ratio-1992",
+    url: "https://pubmed.ncbi.nlm.nih.gov/1342260/"
+  },
+  "caulfield-ionmobility-2008": {
+    abnt: "CAULFIELD, M. P. et al. Direct determination of lipoprotein particle sizes and concentrations by ion mobility analysis. Clinical Chemistry, v. 54, n. 8, p. 1307-1316, 2008.",
+    doi: "10.1373/clinchem.2007.100586",
+    key: "caulfield-ionmobility-2008",
+    url: "https://pubmed.ncbi.nlm.nih.gov/18515257/"
+  },
+  "contois-apoa1-1996": {
+    abnt: "CONTOIS, J. H. et al. Reference intervals for plasma apolipoprotein A-1 determined with a standardized commercial immunoturbidimetric assay: results from the Framingham Offspring Study. Clinical Chemistry, v. 42, n. 4, p. 507-514, 1996.",
+    doi: "10.1093/clinchem/42.4.507",
+    key: "contois-apoa1-1996",
+    url: "https://pubmed.ncbi.nlm.nih.gov/8605666/"
+  },
+  "ewgsop2-2019": {
+    abnt: "CRUZ-JENTOFT, A. J. et al. Sarcopenia: revised European consensus on definition and diagnosis. Age and Ageing, v. 48, n. 1, p. 16-31, 2019.",
+    doi: "10.1093/ageing/afy169",
+    key: "ewgsop2-2019",
+    url: "https://pubmed.ncbi.nlm.nih.gov/30312372/"
+  },
+  "ferreira-vitd-2017": {
+    abnt: "FERREIRA, C. E. S. et al. Posicionamento oficial da Sociedade Brasileira de Patologia Cl\xEDnica/Medicina Laboratorial e da Sociedade Brasileira de Endocrinologia e Metabologia sobre intervalos de refer\xEAncia da vitamina D [25(OH)D]. Archives of Endocrinology and Metabolism, v. 61, n. 6, p. 527-542, 2017.",
+    doi: "10.1590/2359-3997000000310",
+    key: "ferreira-vitd-2017",
+    url: "https://pubmed.ncbi.nlm.nih.gov/29412389/"
+  },
+  "friedewald-1972": {
+    abnt: "FRIEDEWALD, W. T.; LEVY, R. I.; FREDRICKSON, D. S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clinical Chemistry, v. 18, n. 6, p. 499-502, 1972.",
+    doi: "10.1093/clinchem/18.6.499",
+    key: "friedewald-1972",
+    url: "https://pubmed.ncbi.nlm.nih.gov/4337382/"
+  },
+  "gallagher-bodyfat-2000": {
+    abnt: "GALLAGHER, D. et al. Healthy percentage body fat ranges: an approach for developing guidelines based on body mass index. American Journal of Clinical Nutrition, v. 72, n. 3, p. 694-701, 2000.",
+    key: "gallagher-bodyfat-2000",
+    url: "https://pubmed.ncbi.nlm.nih.gov/10966886/"
+  },
+  "ge-corescan": {
+    abnt: "GE HEALTHCARE. enCORE Software CoreScan: Visceral Adipose Tissue (VAT) assessment. Madison: GE Medical Systems Lunar, [s. d.]. (Documenta\xE7\xE3o do fabricante do DEXA Lunar Prodigy; classifica\xE7\xE3o Healthy 0\u201352 in\xB3, Increased Risk 52,15\u2013112,10 in\xB3, At Risk 112,10+ in\xB3, equivalente a 0\u2013852 cm\xB3, 854\u20131.837 cm\xB3, 1.837+ cm\xB3.)",
+    key: "ge-corescan",
+    url: "https://www.gehealthcare.com/products/bone-and-metabolic-health/encore"
+  },
+  "geloneze-brams-2009": {
+    abnt: "GELONEZE, B. et al. HOMA1-IR and HOMA2-IR indexes in identifying insulin resistance and metabolic syndrome \u2014 Brazilian Metabolic Syndrome Study (BRAMS). Arquivos Brasileiros de Endocrinologia & Metabologia, v. 53, n. 2, p. 281-287, 2009.",
+    doi: "10.1590/S0004-27302009000200020",
+    key: "geloneze-brams-2009",
+    url: "https://pubmed.ncbi.nlm.nih.gov/19466221/"
+  },
+  "george-ck-2016": {
+    abnt: "GEORGE, M. D.; MCGILL, N. K.; BAKER, J. F. Creatine kinase in the U.S. population: impact of demographics, comorbidities, and body composition on the normal range. Medicine, v. 95, n. 33, e4344, 2016.",
+    doi: "10.1097/MD.0000000000004344",
+    key: "george-ck-2016",
+    url: "https://pubmed.ncbi.nlm.nih.gov/27537560/"
+  },
+  "giannitsis-hstnt-2010": {
+    abnt: "GIANNITSIS, E. et al. Analytical validation of a high-sensitivity cardiac troponin T assay. Clinical Chemistry, v. 56, n. 2, p. 254-261, 2010.",
+    doi: "10.1373/clinchem.2009.132654",
+    key: "giannitsis-hstnt-2010",
+    url: "https://pubmed.ncbi.nlm.nih.gov/19959623/"
+  },
+  "glis-2024": {
+    abnt: "KIRK, B. et al. The conceptual definition of sarcopenia: Delphi consensus from the Global Leadership Initiative in Sarcopenia (GLIS). Age and Ageing, v. 53, n. 3, afae052, 2024.",
+    doi: "10.1093/ageing/afae052",
+    key: "glis-2024",
+    url: "https://pubmed.ncbi.nlm.nih.gov/38520141/"
+  },
+  // ---------------------------------------------------------------------------
+  // Fontes internacionais — Ácidos graxos ômega
+  // ---------------------------------------------------------------------------
+  "harris-omega3-2004": {
+    abnt: "HARRIS, W. S.; VON SCHACKY, C. The Omega-3 Index: a new risk factor for death from coronary heart disease? Preventive Medicine, v. 39, n. 1, p. 212-220, 2004.",
+    doi: "10.1016/j.ypmed.2004.02.030",
+    key: "harris-omega3-2004",
+    url: "https://pubmed.ncbi.nlm.nih.gov/15208005/"
+  },
+  // ---------------------------------------------------------------------------
+  // Referência laboratorial geral
+  // ---------------------------------------------------------------------------
+  "kalaria-ck-ri-2026": {
+    abnt: "KALARIA, T. et al. Age, sex and ethnicity changes in creatine kinase and sex- and ethnicity-specific reference intervals of creatine kinase. Clinical Medicine, v. 26, n. 4, p. 100596, 2026.",
+    doi: "10.1016/j.clinme.2026.100596",
+    key: "kalaria-ck-ri-2026",
+    url: "https://pubmed.ncbi.nlm.nih.gov/42142664/"
+  },
+  // ---------------------------------------------------------------------------
+  // Fontes internacionais — Nefrologia
+  // ---------------------------------------------------------------------------
+  "kdigo-ckd-2024": {
+    abnt: "KIDNEY DISEASE: IMPROVING GLOBAL OUTCOMES (KDIGO) CKD Work Group. KDIGO 2024 Clinical Practice Guideline for the Evaluation and Management of Chronic Kidney Disease. Kidney International, v. 105, n. 4S, p. S117-S314, 2024.",
+    doi: "10.1016/j.kint.2023.10.018",
+    key: "kdigo-ckd-2024",
+    url: "https://pubmed.ncbi.nlm.nih.gov/38490803/"
+  },
+  "keller-tni-2013": {
+    abnt: "KELLER, T. et al. Defining a reference population to determine the 99th percentile of a contemporary sensitive cardiac troponin I assay. International Journal of Cardiology, v. 167, n. 4, p. 1423-1429, 2013.",
+    doi: "10.1016/j.ijcard.2012.04.063",
+    key: "keller-tni-2013",
+    url: "https://pubmed.ncbi.nlm.nih.gov/22560907/"
+  },
+  "kelly-dxa-2009": {
+    abnt: "KELLY, T. L. et al. Dual energy X-ray absorptiometry body composition reference values from NHANES. PLoS One, v. 4, n. 9, e7038, 2009.",
+    doi: "10.1371/journal.pone.0007038",
+    key: "kelly-dxa-2009",
+    url: "https://pubmed.ncbi.nlm.nih.gov/19753111/"
+  },
+  "khetarpal-apociii-2016": {
+    abnt: "KHETARPAL, S. A. et al. Why is apolipoprotein CIII emerging as a novel therapeutic target to reduce the burden of cardiovascular disease? Current Atherosclerosis Reports, v. 18, n. 10, p. 59, 2016.",
+    key: "khetarpal-apociii-2016",
+    url: "https://pmc.ncbi.nlm.nih.gov/articles/PMC5018018/"
+  },
+  "klee-bhb-2020": {
+    abnt: "KLEE, P. et al. Test validation, method comparison and reference range for the measurement of \u03B2-hydroxybutyrate in peripheral blood samples. Practical Laboratory Medicine, v. 18, e00146, 2020.",
+    doi: "10.1016/j.plabm.2019.e00146",
+    key: "klee-bhb-2020",
+    url: "https://pmc.ncbi.nlm.nih.gov/articles/PMC6999181/"
+  },
+  "maisel-bnp-2002": {
+    abnt: "MAISEL, A. S. et al. Rapid measurement of B-type natriuretic peptide in the emergency diagnosis of heart failure. New England Journal of Medicine, v. 347, n. 3, p. 161-167, 2002.",
+    doi: "10.1056/NEJMoa020233",
+    key: "maisel-bnp-2002",
+    url: "https://pubmed.ncbi.nlm.nih.gov/12124404/"
+  },
+  "meuwese-mpo-2007": {
+    abnt: "MEUWESE, M. C. et al. Serum myeloperoxidase levels are associated with the future risk of coronary artery disease in apparently healthy individuals: the EPIC-Norfolk Prospective Population Study. Journal of the American College of Cardiology, v. 50, n. 2, p. 159-165, 2007.",
+    doi: "10.1016/j.jacc.2007.03.033",
+    key: "meuwese-mpo-2007",
+    url: "https://pubmed.ncbi.nlm.nih.gov/17616301/"
+  },
+  // ---------------------------------------------------------------------------
+  // Fontes internacionais — Marcadores metabólicos e inflamatórios
+  // ---------------------------------------------------------------------------
+  "nemeth-adma-2017": {
+    abnt: "NEMETH, B. et al. The issue of plasma asymmetric dimethylarginine reference range: a systematic review and meta-analysis. PLoS One, v. 12, n. 5, e0177493, 2017.",
+    doi: "10.1371/journal.pone.0177493",
+    key: "nemeth-adma-2017",
+    url: "https://pubmed.ncbi.nlm.nih.gov/28494019/"
+  },
+  // ---------------------------------------------------------------------------
+  // Fontes brasileiras — Metais pesados (NR-7)
+  // ---------------------------------------------------------------------------
+  "nr7-pcmso-2020": {
+    abnt: "BRASIL. Minist\xE9rio do Trabalho e Emprego. NR-7 \u2014 PCMSO, Quadro 1: Indicadores biol\xF3gicos. Portaria n. 6.734, de 9 de mar\xE7o de 2020. Di\xE1rio Oficial da Uni\xE3o, Bras\xEDlia, 13 mar. 2020.",
+    key: "nr7-pcmso-2020",
+    url: "https://www.gov.br/trabalho-e-emprego/pt-br/assuntos/inspecao-do-trabalho/seguranca-e-saude-no-trabalho/sst-portarias/2022/portaria-no-567-de-10-de-marco-de-2022-alteracoes-na-nr-7.pdf"
+  },
+  "ofenheimer-vat-2020": {
+    abnt: "OFENHEIMER, A. et al. Reference values of body composition parameters and visceral adipose tissue (VAT) by DXA in adults aged 18-81 years: results from the LEAD cohort. European Journal of Clinical Nutrition, v. 74, p. 1181-1191, 2020.",
+    doi: "10.1038/s41430-020-0596-5",
+    key: "ofenheimer-vat-2020",
+    url: "https://pubmed.ncbi.nlm.nih.gov/32123345/"
+  },
+  "pns-bioquimica-2019": {
+    abnt: "SZWARCWALD, C. L. et al. Valores de refer\xEAncia para exames laboratoriais de colesterol, hemoglobina glicosilada e creatinina da popula\xE7\xE3o adulta brasileira. Revista Brasileira de Epidemiologia, v. 22, supl. 2, e190002.supl.2, 2019.",
+    doi: "10.1590/1980-549720190002.supl.2",
+    key: "pns-bioquimica-2019",
+    url: "https://pubmed.ncbi.nlm.nih.gov/31596373/"
+  },
+  // ---------------------------------------------------------------------------
+  // Pesquisa Nacional de Saúde (PNS) — Intervalos de referência brasileiros
+  // ---------------------------------------------------------------------------
+  "pns-hemograma-2019": {
+    abnt: "ROSENFELD, L. G. et al. Valores de refer\xEAncia para exames laboratoriais de hemograma da popula\xE7\xE3o adulta brasileira: Pesquisa Nacional de Sa\xFAde. Revista Brasileira de Epidemiologia, v. 22, supl. 2, e190003.supl.2, 2019.",
+    doi: "10.1590/1980-549720190003.supl.2",
+    key: "pns-hemograma-2019",
+    url: "https://pubmed.ncbi.nlm.nih.gov/31596374/"
+  },
+  "pns-renal-2019": {
+    abnt: "MALTA, D. C. et al. Evaluation of renal function in the Brazilian adult population, according to laboratory criteria from the National Health Survey. Revista Brasileira de Epidemiologia, v. 22, supl. 2, e190010.supl.2, 2019.",
+    doi: "10.1590/1980-549720190010.supl.2",
+    key: "pns-renal-2019",
+    url: "https://pubmed.ncbi.nlm.nih.gov/31596381/"
+  },
+  "rumberger-cac-1999": {
+    abnt: "RUMBERGER, J. A. et al. Electron beam computed tomographic coronary calcium scanning: a review and guidelines for use in asymptomatic persons. Mayo Clinic Proceedings, v. 74, n. 3, p. 243-252, 1999.",
+    doi: "10.4065/74.3.243",
+    key: "rumberger-cac-1999",
+    url: "https://pubmed.ncbi.nlm.nih.gov/10089993/"
+  },
+  "sbc-ic-2018": {
+    abnt: "ROHDE, L. E. P. et al. Diretriz Brasileira de Insufici\xEAncia Card\xEDaca Cr\xF4nica e Aguda. Arquivos Brasileiros de Cardiologia, S\xE3o Paulo, v. 111, n. 3, p. 436-539, set. 2018.",
+    doi: "10.5935/abc.20180190",
+    key: "sbc-ic-2018",
+    url: "https://pubmed.ncbi.nlm.nih.gov/30379264/"
+  },
+  // ---------------------------------------------------------------------------
+  // Sociedade Brasileira de Cardiologia
+  // ---------------------------------------------------------------------------
+  "sbc-lipids-2017": {
+    abnt: "FALUDI, A. A. et al. Atualiza\xE7\xE3o da Diretriz Brasileira de Dislipidemias e Preven\xE7\xE3o da Aterosclerose \u2013 2017. Arquivos Brasileiros de Cardiologia, S\xE3o Paulo, v. 109, n. 2, supl. 1, p. 1-76, ago. 2017.",
+    doi: "10.5935/abc.20170121",
+    key: "sbc-lipids-2017",
+    url: "https://www.scielo.br/j/abc/a/whBsCyzTDzGYJcsBY7YVkWn/?lang=pt"
+  },
+  "sbc-lipids-2025": {
+    abnt: "RACHED, F. H. et al. Diretriz Brasileira de Dislipidemias e Preven\xE7\xE3o da Aterosclerose \u2013 2025. Arquivos Brasileiros de Cardiologia, S\xE3o Paulo, v. 122, n. 9, e20250640, out. 2025.",
+    doi: "10.36660/abc.20250640",
+    key: "sbc-lipids-2025",
+    url: "https://pmc.ncbi.nlm.nih.gov/articles/PMC12674852/"
+  },
+  // ---------------------------------------------------------------------------
+  // Sociedade Brasileira de Diabetes
+  // ---------------------------------------------------------------------------
+  "sbd-diabetes-2024": {
+    // Chave mantida como 'sbd-diabetes-2024' para compatibilidade com
+    // consumidores publicados; a diretriz correspondente é o documento vivo
+    // de diretriz.diabetes.org.br, cuja edição citada quando este registro foi
+    // atualizado é "Edição 2025". Semelhante ao caso de sbpc-ml-2021 abaixo.
+    abnt: "SOCIEDADE BRASILEIRA DE DIABETES (SBD). Diretriz da Sociedade Brasileira de Diabetes \u2014 Edi\xE7\xE3o 2025. S\xE3o Paulo: SBD, 2025.",
+    doi: "10.29327/5660187",
+    isbn: "978-65-272-1932-3",
+    key: "sbd-diabetes-2024",
+    url: "https://diretriz.diabetes.org.br"
+  },
+  // ---------------------------------------------------------------------------
+  // Sociedade Brasileira de Endocrinologia e Metabologia
+  // ---------------------------------------------------------------------------
+  "sbem-thyroid-2013": {
+    abnt: "SGARBI, J. A. et al. Consenso brasileiro para a abordagem cl\xEDnica e tratamento do hipotireoidismo subcl\xEDnico em adultos. Arquivos Brasileiros de Endocrinologia & Metabologia, v. 57, n. 3, p. 166-183, 2013.",
+    doi: "10.1590/S0004-27302013000300003",
+    key: "sbem-thyroid-2013",
+    url: "https://pubmed.ncbi.nlm.nih.gov/23681263/"
+  },
+  "sbem-vitamind-2014": {
+    abnt: "MAEDA, S. S. et al. Recomenda\xE7\xF5es da Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) para o diagn\xF3stico e tratamento da hipovitaminose D. Arquivos Brasileiros de Endocrinologia & Metabologia, v. 58, n. 5, p. 411-433, 2014.",
+    doi: "10.1590/0004-2730000003388",
+    key: "sbem-vitamind-2014",
+    url: "https://pubmed.ncbi.nlm.nih.gov/25166032/"
+  },
+  // ---------------------------------------------------------------------------
+  // Sociedade Brasileira de Patologia Clínica / Medicina Laboratorial
+  // ---------------------------------------------------------------------------
+  "sbpc-ml-2021": {
+    // Chave mantida como 'sbpc-ml-2021' para compatibilidade com consumidores;
+    // a edição autoritativa é de 2020 (verificada na Biblioteca Digital SBPC/ML
+    // em 2026-04-18). Ano na citação ABNT reflete a edição real.
+    abnt: "SOCIEDADE BRASILEIRA DE PATOLOGIA CL\xCDNICA/MEDICINA LABORATORIAL (SBPC/ML). Recomenda\xE7\xF5es da Sociedade Brasileira de Patologia Cl\xEDnica/Medicina Laboratorial (SBPC/ML): Boas Pr\xE1ticas em Laborat\xF3rio Cl\xEDnico. S\xE3o Paulo: SBPC/ML, 2020.",
+    key: "sbpc-ml-2021",
+    url: "https://bibliotecasbpc.org.br/index.php?P=4&C=0.2.443"
+  },
+  "schumann-ifcc-ldh-2002": {
+    abnt: "SCHUMANN, G.; KLAUKE, R. New IFCC reference procedures for the determination of catalytic activity concentrations of five enzymes in serum: preliminary upper reference limits obtained in hospitalized subjects. Clinica Chimica Acta, v. 327, n. 1-2, p. 69-79, 2003.",
+    doi: "10.1016/S0009-8981(02)00341-8",
+    key: "schumann-ifcc-ldh-2002",
+    url: "https://pubmed.ncbi.nlm.nih.gov/12482620/"
+  },
+  "schwedhelm-sdma-2011": {
+    abnt: "SCHWEDHELM, E. et al. Plasma symmetric dimethylarginine reference limits from the Framingham Offspring Cohort. Clinical Chemistry and Laboratory Medicine, v. 49, n. 11, p. 1907-1910, 2011.",
+    doi: "10.1515/CCLM.2011.679",
+    key: "schwedhelm-sdma-2011",
+    url: "https://pubmed.ncbi.nlm.nih.gov/21864208/"
+  },
+  "selhub-homocysteine-1999": {
+    abnt: "SELHUB, J. et al. Serum total homocysteine concentrations in the third National Health and Nutrition Examination Survey (1991-1994): population reference ranges and contribution of vitamin status to high serum concentrations. Annals of Internal Medicine, v. 131, n. 5, p. 331-339, 1999.",
+    doi: "10.7326/0003-4819-131-5-199909070-00003",
+    key: "selhub-homocysteine-1999",
+    url: "https://pubmed.ncbi.nlm.nih.gov/10475885/"
+  },
+  "simopoulos-omega-ratio-2002": {
+    abnt: "SIMOPOULOS, A. P. The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomedicine & Pharmacotherapy, v. 56, n. 8, p. 365-379, 2002.",
+    doi: "10.1016/S0753-3322(02)00253-6",
+    key: "simopoulos-omega-ratio-2002",
+    url: "https://pubmed.ncbi.nlm.nih.gov/12442909/"
+  },
+  // ---------------------------------------------------------------------------
+  // Fontes internacionais — Marcadores tumorais
+  // ---------------------------------------------------------------------------
+  "sturgeon-nacb-2008": {
+    abnt: "STURGEON, C. M. et al. National Academy of Clinical Biochemistry Laboratory Medicine Practice Guidelines for use of tumor markers in testicular, prostate, colorectal, breast, and ovarian cancers. Clinical Chemistry, v. 54, n. 12, p. e11-e79, 2008.",
+    doi: "10.1373/clinchem.2008.105601",
+    key: "sturgeon-nacb-2008",
+    url: "https://pubmed.ncbi.nlm.nih.gov/19042984/"
+  },
+  "tietz-7ed-2015": {
+    abnt: "BURTIS, C. A.; BRUNS, D. E. Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics. 7. ed. St. Louis: Elsevier Saunders, 2015.",
+    isbn: "978-1-4557-4165-6",
+    key: "tietz-7ed-2015"
+  },
+  "torrissen-omega3-dbs-2025": {
+    abnt: "TORRISSEN, M. et al. Global variations in omega-3 fatty acid status and omega-6:omega-3 ratios: insights from > 500,000 whole-blood dried blood spot samples. Lipids in Health and Disease, v. 24, n. 1, p. 260, 2025.",
+    doi: "10.1186/s12944-025-02676-6",
+    key: "torrissen-omega3-dbs-2025",
+    url: "https://pubmed.ncbi.nlm.nih.gov/40783537/"
+  },
+  // ---------------------------------------------------------------------------
+  // Fontes internacionais — Coagulação
+  // ---------------------------------------------------------------------------
+  "wells-ddimer-2003": {
+    abnt: "WELLS, P. S. et al. Evaluation of D-dimer in the diagnosis of suspected deep-vein thrombosis. New England Journal of Medicine, v. 349, p. 1227-1235, 2003.",
+    doi: "10.1056/NEJMoa023153",
+    key: "wells-ddimer-2003",
+    url: "https://pubmed.ncbi.nlm.nih.gov/14507948/"
+  },
+  // ---------------------------------------------------------------------------
+  // Fontes internacionais — OMS
+  // ---------------------------------------------------------------------------
+  "who-iron-2020": {
+    abnt: "WORLD HEALTH ORGANIZATION. WHO guideline on use of ferritin concentrations to assess iron status in individuals and populations. Geneva: WHO, 2020.",
+    isbn: "978-92-4-000012-4",
+    key: "who-iron-2020",
+    url: "https://www.who.int/publications/i/item/9789240000124"
+  },
+  "who-obesity-2000": {
+    abnt: "WORLD HEALTH ORGANIZATION. Obesity: preventing and managing the global epidemic. WHO Technical Report Series, n. 894. Geneva: WHO, 2000.",
+    isbn: "92-4-120894-5",
+    key: "who-obesity-2000"
+  },
+  "who-osteoporosis-1994": {
+    abnt: "WHO STUDY GROUP. Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. WHO Technical Report Series, n. 843. Geneva: WHO, 1994.",
+    key: "who-osteoporosis-1994",
+    url: "https://pubmed.ncbi.nlm.nih.gov/7941614/"
+  }
+};
+function extractSourceKey(source2) {
+  return source2.split(":")[0] ?? source2;
+}
+
+// src/cli/commands/source.ts
+function render(ref) {
+  const linhas = [`Fonte: ${ref.key}`, "", ref.abnt];
+  if (ref.doi) linhas.push("", `DOI:  ${ref.doi}`);
+  if (ref.isbn) linhas.push(`ISBN: ${ref.isbn}`);
+  if (ref.url) linhas.push(`URL:  ${ref.url}`);
+  return linhas.join("\n");
+}
+async function source(args, json) {
+  const { positionals, values } = parseArgs3({
+    allowPositionals: true,
+    args,
+    options: { biomarker: { short: "b", type: "string" } },
+    strict: false
+  });
+  if (values.biomarker) {
+    const code = values.biomarker;
+    if (!getDefinitionByCode(code)) exitWithError(`Biomarcador n\xE3o encontrado: ${code}`);
+    const def = biomarkerRangeDefinitions[code];
+    if (!def?.source) exitWithError(`Sem faixa de refer\xEAncia com fonte para: ${code}`);
+    const chave2 = extractSourceKey(def.source);
+    const ref2 = SOURCE_REGISTRY[chave2];
+    if (!ref2) exitWithError(`Fonte n\xE3o encontrada no registro: ${chave2}`);
+    if (json) outputJson(ref2);
+    else outputText(render(ref2));
+    return;
+  }
+  const chave = positionals[0];
+  if (!chave) {
+    const todas = Object.values(SOURCE_REGISTRY).sort((a, b) => a.key.localeCompare(b.key));
+    if (json) {
+      outputJson(todas);
+      return;
+    }
+    outputText(
+      [
+        `Fontes no registro: ${todas.length}`,
+        "",
+        ...todas.map((r) => `  ${r.key.padEnd(28)} ${r.abnt.slice(0, 60)}\u2026`),
+        "",
+        "Detalhe de uma: fhir-bio source <chave>",
+        "A partir do exame:  fhir-bio source --biomarker TSH"
+      ].join("\n")
+    );
+    return;
+  }
+  const limpa = extractSourceKey(chave);
+  const ref = SOURCE_REGISTRY[limpa];
+  if (!ref) {
+    const alvo = limpa === chave ? chave : `${chave} (procurado como ${limpa})`;
+    exitWithError(`Fonte n\xE3o encontrada: ${alvo}
+Veja a lista com: fhir-bio source`);
+  }
+  if (json) outputJson(ref);
+  else outputText(render(ref));
+}
+
 // src/cli/commands/units.ts
 async function units(args, json) {
   const code = args[0];
@@ -6803,6 +7235,7 @@ Comandos:
   list                    Listar todos os biomarcadores
   categories              Listar biomarcadores agrupados por categoria
   range <c\xF3digo>          Faixa de refer\xEAncia para um biomarcador
+  source [chave]          Cita\xE7\xE3o de uma fonte, ou a lista toda
   units <c\xF3digo>          Informa\xE7\xF5es de unidade de um biomarcador
   convert <arquivo>       Converter dados lab (JSON) para FHIR Bundle
   validate <arquivo>      Validar recurso FHIR (Bundle, Observation ou DiagnosticReport)
@@ -6823,26 +7256,18 @@ var COMMANDS = {
   lookup,
   "lookup-loinc": lookupLoinc,
   range,
+  source,
   units,
   validate
 };
 async function main() {
-  const { positionals, values } = parseArgs3({
-    allowPositionals: true,
-    options: {
-      help: { default: false, short: "h", type: "boolean" },
-      json: { default: false, type: "boolean" },
-      version: { default: false, short: "v", type: "boolean" }
-    },
-    strict: false
-  });
-  if (values.version) {
-    process.stdout.write(`${"0.31.5"}
+  const { command, help, json, resto, version } = dividirArgv(process.argv.slice(2));
+  if (version) {
+    process.stdout.write(`${"0.32.0"}
 `);
     return;
   }
-  const [command, ...rest] = positionals;
-  if (values.help || !command) {
+  if (help || !command) {
     process.stdout.write(HELP);
     return;
   }
@@ -6851,6 +7276,6 @@ async function main() {
     exitWithError(`Comando desconhecido: ${command}
 Use --help para ver os comandos dispon\xEDveis.`);
   }
-  await handler(rest, Boolean(values.json));
+  await handler(resto, json);
 }
 main().catch((err) => exitWithError(err.message));

package/dist/converter.cjs

@@ -3,14 +3,14 @@
 
 
 
-var _chunkEXOKBY6Dcjs = require('./chunk-EXOKBY6D.cjs');
+var _chunkOTVCOSCKcjs = require('./chunk-OTVCOSCK.cjs');
 require('./chunk-OR67NJDZ.cjs');
-require('./chunk-QOXTLPQ2.cjs');
+require('./chunk-MKH4Q735.cjs');
 require('./chunk-AZTZYOAV.cjs');
 
 
 
 
 
-exports.labObservationToFHIR = _chunkEXOKBY6Dcjs.labObservationToFHIR; exports.labReportToFHIR = _chunkEXOKBY6Dcjs.labReportToFHIR; exports.labResultToFHIRBundle = _chunkEXOKBY6Dcjs.labResultToFHIRBundle; exports.userProfileToFHIR = _chunkEXOKBY6Dcjs.userProfileToFHIR;
+exports.labObservationToFHIR = _chunkOTVCOSCKcjs.labObservationToFHIR; exports.labReportToFHIR = _chunkOTVCOSCKcjs.labReportToFHIR; exports.labResultToFHIRBundle = _chunkOTVCOSCKcjs.labResultToFHIRBundle; exports.userProfileToFHIR = _chunkOTVCOSCKcjs.userProfileToFHIR;
 //# sourceMappingURL=converter.cjs.map

package/dist/converter.js

@@ -3,9 +3,9 @@ import {
   labReportToFHIR,
   labResultToFHIRBundle,
   userProfileToFHIR
-} from "./chunk-6OG25HIE.js";
+} from "./chunk-MNUQ57JR.js";
 import "./chunk-A6HR4XDK.js";
-import "./chunk-PK5DQMPC.js";
+import "./chunk-WDDW2WCY.js";
 import "./chunk-3XIMPALK.js";
 export {
   labObservationToFHIR,

package/dist/importer.cjs

@@ -4,15 +4,15 @@
 
 
 
-var _chunkSDKLR3DTcjs = require('./chunk-SDKLR3DT.cjs');
-require('./chunk-OR67NJDZ.cjs');
-require('./chunk-QOXTLPQ2.cjs');
+var _chunk44QMNDOIcjs = require('./chunk-44QMNDOI.cjs');
 require('./chunk-3ILBFLVQ.cjs');
+require('./chunk-OR67NJDZ.cjs');
+require('./chunk-MKH4Q735.cjs');
 
 
 
 
 
 
-exports.MAX_FILE_SIZE = _chunkSDKLR3DTcjs.MAX_FILE_SIZE; exports.MAX_OBSERVATIONS = _chunkSDKLR3DTcjs.MAX_OBSERVATIONS; exports.extractObservationsFromBundle = _chunkSDKLR3DTcjs.extractObservationsFromBundle; exports.mapFHIRObservationToInternal = _chunkSDKLR3DTcjs.mapFHIRObservationToInternal; exports.processImportBundle = _chunkSDKLR3DTcjs.processImportBundle;
+exports.MAX_FILE_SIZE = _chunk44QMNDOIcjs.MAX_FILE_SIZE; exports.MAX_OBSERVATIONS = _chunk44QMNDOIcjs.MAX_OBSERVATIONS; exports.extractObservationsFromBundle = _chunk44QMNDOIcjs.extractObservationsFromBundle; exports.mapFHIRObservationToInternal = _chunk44QMNDOIcjs.mapFHIRObservationToInternal; exports.processImportBundle = _chunk44QMNDOIcjs.processImportBundle;
 //# sourceMappingURL=importer.cjs.map

package/dist/importer.js

@@ -4,10 +4,10 @@ import {
   extractObservationsFromBundle,
   mapFHIRObservationToInternal,
   processImportBundle
-} from "./chunk-RM7KJAVA.js";
-import "./chunk-A6HR4XDK.js";
-import "./chunk-PK5DQMPC.js";
+} from "./chunk-4Y43MQQK.js";
 import "./chunk-N3ZCOLG2.js";
+import "./chunk-A6HR4XDK.js";
+import "./chunk-WDDW2WCY.js";
 export {
   MAX_FILE_SIZE,
   MAX_OBSERVATIONS,