@platforma-open/milaboratories.sequence-properties.model 1.1.1

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package/.oxfmtrc.json ADDED
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+ {
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+ "ignorePatterns": ["dist", "CHANGELOG.md"]
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+ }
package/.oxlintrc.json ADDED
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+ {
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+ "extends": ["node_modules/@milaboratories/ts-builder/dist/configs/oxlint-block-model.json"]
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+ }
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+  WARN  Issue while reading "/home/runner/work/sequence-properties/sequence-properties/.npmrc". Failed to replace env in config: ${NPMJS_TOKEN}
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+
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+ > @platforma-open/milaboratories.sequence-properties.model@1.1.1 build /home/runner/work/sequence-properties/sequence-properties/model
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+ > ts-builder build --target block-model && block-tools build-model
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+
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+ Building block-model project...
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+ ↳ cli.mjs -c /home/runner/work/sequence-properties/sequence-properties/node_modules/.pnpm/@milaboratories+ts-builder@1.3.2_@types+node@25.3.2_rollup@4.53.3_vue@3.5.25_typescript@5.6.3__yaml@2.8.1/node_modules/@milaboratories/ts-builder/dist/configs/rolldown.block-model.config.js
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+ [PLUGIN_TIMINGS] Warning: Your build spent significant time in plugin `rolldown-plugin-dts:generate`. See https://rolldown.rs/options/checks#plugintimings for more details.
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+
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+ [log] <DIR>/dataModel.d.ts.map asset │ size: 0.14 kB
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+ [log] <DIR>/types.d.ts.map asset │ size: 0.31 kB
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+ [log] <DIR>/dataModel.js.map asset │ size: 0.49 kB
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+ [log] <DIR>/index.d.ts.map asset │ size: 1.96 kB
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+ [log] <DIR>/index.js.map asset │ size: 5.91 kB
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+ [log] <DIR>/dataModel.d.ts chunk │ size: 0.29 kB
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+ [log] <DIR>/dataModel.js chunk │ size: 0.32 kB
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+ [log] <DIR>/types.d.ts chunk │ size: 0.71 kB
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+ [log] <DIR>/index.js chunk │ size: 2.46 kB
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+ [log] <DIR>/index.d.ts chunk │ size: 56.81 kB
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+ [log] <DIR>/dataModel.cjs.map asset │ size: 0.53 kB
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+ [log] <DIR>/index.cjs.map asset │ size: 6.04 kB
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+ [log] <DIR>/dataModel.cjs chunk │ size: 0.35 kB
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+ [log] <DIR>/index.cjs chunk │ size: 2.69 kB
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+ [log] <DIR>/bundle.js.map asset │ size: 675.99 kB
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+ [log] <DIR>/bundle.js chunk │ size: 343.70 kB
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+ [log]
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+ [success] rolldown v1.0.0-rc.16 Finished in 5.42 s
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+ Build completed successfully
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+  WARN  Issue while reading "/home/runner/work/sequence-properties/sequence-properties/.npmrc". Failed to replace env in config: ${NPMJS_TOKEN}
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+
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+ > @platforma-open/milaboratories.sequence-properties.model@1.1.1 check /home/runner/work/sequence-properties/sequence-properties/model
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+ > ts-builder check --target block-model
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+
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+ ↳ tsc --noEmit --project ./tsconfig.json --customConditions ,
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+ Linting project...
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+ ↳ oxlint --config /home/runner/work/sequence-properties/sequence-properties/model/.oxlintrc.json --deny-warnings
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+ Found 0 warnings and 0 errors.
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+ Finished in 8ms on 3 files with 90 rules using 2 threads.
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+ Linting completed successfully
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+ Checking formatting...
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+ ↳ oxfmt --check --config /home/runner/work/sequence-properties/sequence-properties/model/.oxfmtrc.json
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+ Checking formatting...
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+
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+ All matched files use the correct format.
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+ Finished in 252ms on 7 files using 2 threads.
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+ Format check completed successfully
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+ All checks passed!
package/CHANGELOG.md ADDED
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+ # @platforma-open/MiLaboratories.sequence-properties.model
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+
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+ ## 1.1.1
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+
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+ ### Patch Changes
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+
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+ - bb07f98: Rename all package scopes from `MiLaboratories.sequence-properties` to `milaboratories.sequence-properties`. npm registry rejects new package names with uppercase letters, which blocked the first publish. Lowercase form aligns with the existing `@platforma-open/milaboratories.*` convention used by sibling blocks. Also corrects the GitHub URL in the block manifest to point at the actual repo (`platforma-open/sequence-properties`).
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+
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+ ## 1.1.0
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+
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+ ### Minor Changes
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+
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+ - 1059d80: Initial release of the Sequence Properties block.
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+
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+ Computes physico-chemical properties (charge, pI, GRAVY, MW, extinction
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+ coefficients, instability and aliphatic indices, aromaticity, AA composition)
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+ for peptide and antibody/TCR sequence inputs. The block auto-detects modality
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+ from the input axes and degrades gracefully on partial coverage: CDR3
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+ properties when CDR3 is present, full-chain VH/VL when all seven IMGT regions
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+ are exported, and Fv-level properties when both chains reconstruct. An R11c
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+ heuristic flags likely VHH/single-domain inputs.
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+
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+ Property math uses BioPython ProtParam + IsoelectricPoint with IPC 2.0 pKa
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+ overrides — peptide set for peptide and CDR3 inputs, protein set for full
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+ VH/VL. Charge and pI round to 3 decimals at the output boundary; combined
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+ with sorted Tengo iteration, canonical-JSON resources, and sorted TSV writes,
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+ output bytes hash identically across runs so the block joins the dedup path.
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+
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+ M3 validation is locked down by `tests/unit/test_m3_validation.py` (38 cases:
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+ ≥5 VH pI, ≥2 VL pI, Fv on ≥2 paired chains, ≥10 CDR-H3 charge, ≥3 CDR-L3
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+ charge, ≥3 VH aliphatic) against pinned IPC 2.0 webserver values and an
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+ independent Henderson-Hasselbalch reference.
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+
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+ Block title is the static "Sequence Properties"; the selected input dataset
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+ appears as the subtitle.