@mcpassure/mcp-anvisa-bulario 0.0.1 → 0.1.0

package/dist/resources/handlers.js

@@ -0,0 +1,145 @@
+export const TARJAS_JSON = JSON.stringify({
+    tarjas: [
+        {
+            codigo: "sem_tarja",
+            nome: "Sem tarja",
+            descricao: "Venda livre — sem retenção de receita.",
+        },
+        {
+            codigo: "amarela",
+            nome: "Tarja Amarela",
+            descricao: "Venda sob prescrição — antibióticos e outros medicamentos sujeitos a controle.",
+        },
+        {
+            codigo: "vermelha",
+            nome: "Tarja Vermelha",
+            descricao: "Venda sob prescrição médica — receita simples retida.",
+        },
+        {
+            codigo: "preta",
+            nome: "Tarja Preta",
+            descricao: "Controle especial — Portaria 344/98 (psicotrópicos, entorpecentes).",
+        },
+    ],
+    fonte: "RDC ANVISA 357/2020 e Portaria SVS/MS 344/1998",
+}, null, 2);
+const CLASSES_TERAPEUTICAS_HARDCODED = [
+    "Analgésico",
+    "Anti-inflamatório",
+    "Antibiótico",
+    "Antifúngico",
+    "Antiviral",
+    "Antiparasitário",
+    "Anti-hipertensivo",
+    "Antidiabético",
+    "Anticoagulante",
+    "Antiarrítmico",
+    "Diurético",
+    "Broncodilatador",
+    "Corticosteroide",
+    "Imunossupressor",
+    "Antineoplásico",
+    "Ansiolítico",
+    "Antidepressivo",
+    "Antipsicótico",
+    "Antiepiléptico",
+    "Antiparkinsônico",
+    "Opiáceo",
+    "Psicotrópico",
+    "Hormônio",
+    "Anticoncepcional",
+    "Vitamina e Suplemento",
+    "Gastroprotetores",
+    "Antiácido",
+    "Antiemético",
+    "Laxante",
+    "Antidiarreico",
+    "Hipnótico",
+    "Relaxante Muscular",
+    "Imunomodulador",
+    "Vacina",
+    "Hemostático",
+    "Antialérgico",
+    "Descongestionante",
+    "Mucolítico",
+    "Antitussígeno",
+    "Dermatológico",
+    "Oftálmico",
+    "Otológico",
+    "Antisséptico",
+];
+export async function getClassesTerapeuticasJson(_repository) {
+    return JSON.stringify({
+        classes_terapeuticas: CLASSES_TERAPEUTICAS_HARDCODED.sort(),
+        total: CLASSES_TERAPEUTICAS_HARDCODED.length,
+        fonte: "Bulário Eletrônico ANVISA — principais classes indexadas",
+        nota: "Lista representativa. Consulte o Bulário ANVISA para listagem completa atualizada.",
+    }, null, 2);
+}
+export const SCOPE_MARKDOWN = `# Escopo do MCP @mcpassure/mcp-anvisa-bulario
+
+## 🇧🇷 Português (BR)
+
+### O que este MCP faz
+
+Consulta ao **Bulário Eletrônico da ANVISA** (Agência Nacional de Vigilância Sanitária), incluindo:
+
+- Busca de medicamentos por nome comercial, princípio ativo, classe terapêutica ou tarja
+- Recuperação de bulas (paciente e profissional) em PDF via número de registro ANVISA
+- Listagem de apresentações comerciais (concentração, forma farmacêutica, fabricante)
+- Filtragem por tarja regulatória (Livre, Vermelha, Preta)
+- Transport Playwright resistente a proteção Cloudflare do portal ANVISA
+- Cache local SQLite para redução de latência e requisições repetidas
+
+### O que este MCP NÃO faz
+
+- ❌ Não substitui consulta direta à ANVISA para fins regulatórios oficiais
+- ❌ Não fornece preços de medicamentos (consulte CMED/ANVISA)
+- ❌ Não verifica interações medicamentosas
+- ❌ Não emite receitas ou laudos médicos
+- ❌ Não cobre medicamentos fitoterápicos, cosméticos ou saneantes
+- ❌ Não acessa dados de farmacovigilância ou notificações de eventos adversos
+
+### ⚠️ Disclaimer regulatório
+
+Dados obtidos do Bulário Eletrônico ANVISA com latência de cache configurável.
+**Decisões clínicas ou regulatórias devem sempre utilizar a fonte ANVISA oficial e atualizada.**
+
+Medicamentos sob **Tarja Preta** (Portaria SVS/MS 344/1998) estão sujeitos a controle especial —
+psicotrópicos, entorpecentes, precursores e outras substâncias de controle especial.
+O uso inadequado é crime previsto em lei.
+
+---
+
+## 🇺🇸 English
+
+### What this MCP does
+
+Queries the **ANVISA Electronic Drug Information Database** (Brazilian Health Regulatory Agency), including:
+
+- Search medications by trade name, active ingredient (INN/DCB), therapeutic class, or controlled-substance tier
+- Retrieve patient and prescriber leaflets (bulas) in PDF via ANVISA registration number
+- List commercial presentations (dosage, pharmaceutical form, manufacturer)
+- Filter by regulatory tier (Sem Tarja/OTC, Tarja Vermelha/Rx, Tarja Preta/controlled)
+- Cloudflare-resistant Playwright transport for the ANVISA portal
+- Local SQLite cache to reduce latency on repeated queries
+
+### What this MCP does NOT do
+
+- ❌ Does not replace official ANVISA consultation for regulatory compliance
+- ❌ Does not provide drug pricing (see CMED/ANVISA)
+- ❌ Does not check drug interactions
+- ❌ Does not issue prescriptions or medical reports
+- ❌ Does not cover phytotherapeutics, cosmetics, or sanitizers
+- ❌ Does not access pharmacovigilance data or adverse event reports
+
+### ⚠️ Regulatory disclaimer
+
+Data sourced from the ANVISA Electronic Drug Information Database with configurable cache latency.
+**Clinical or regulatory decisions must always use the official and up-to-date ANVISA source.**
+
+Medications classified as **Tarja Preta** (Black-banded — controlled substance under Brazilian
+Ordinance SVS/MS 344/1998) are subject to special control — psychotropics, narcotics, precursors,
+and other controlled substances. Misuse is a criminal offense under Brazilian law.
+`;
+//# sourceMappingURL=handlers.js.map

package/dist/resources/handlers.js.map

@@ -0,0 +1 @@
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package/dist/resources/index.d.ts

@@ -0,0 +1,4 @@
+import type { McpServer } from "@modelcontextprotocol/sdk/server/mcp.js";
+import type { IBularioRepository } from "../domain/repository.js";
+export declare function registerResources(server: McpServer, repository: IBularioRepository): void;
+//# sourceMappingURL=index.d.ts.map

package/dist/resources/index.d.ts.map

@@ -0,0 +1 @@
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package/dist/resources/index.js

@@ -0,0 +1,48 @@
+import { getClassesTerapeuticasJson, SCOPE_MARKDOWN, TARJAS_JSON } from "./handlers.js";
+export function registerResources(server, repository) {
+    server.registerResource("bulario://tarjas", "bulario://tarjas", {
+        title: "Taxonomia de Tarjas ANVISA",
+        description: "Taxonomia regulatória de tarjas (RDC 357/2020, Portaria 344/98). " +
+            "Lista todas as categorias de controle de venda de medicamentos no Brasil.",
+        mimeType: "application/json",
+    }, async () => ({
+        contents: [
+            {
+                uri: "bulario://tarjas",
+                mimeType: "application/json",
+                text: TARJAS_JSON,
+            },
+        ],
+    }));
+    server.registerResource("bulario://classes_terapeuticas", "bulario://classes_terapeuticas", {
+        title: "Classes Terapêuticas Indexadas",
+        description: "Lista das principais classes terapêuticas indexadas no Bulário Eletrônico ANVISA.",
+        mimeType: "application/json",
+    }, async () => {
+        const json = await getClassesTerapeuticasJson(repository);
+        return {
+            contents: [
+                {
+                    uri: "bulario://classes_terapeuticas",
+                    mimeType: "application/json",
+                    text: json,
+                },
+            ],
+        };
+    });
+    server.registerResource("bulario://scope", "bulario://scope", {
+        title: "Escopo do MCP (PT/EN)",
+        description: "Escopo do MCP (PT/EN): o que faz, o que não faz, disclaimer regulatório " +
+            "e atenção especial a Tarja Preta (Portaria 344/98).",
+        mimeType: "text/markdown",
+    }, async () => ({
+        contents: [
+            {
+                uri: "bulario://scope",
+                mimeType: "text/markdown",
+                text: SCOPE_MARKDOWN,
+            },
+        ],
+    }));
+}
+//# sourceMappingURL=index.js.map

package/dist/resources/index.js.map

@@ -0,0 +1 @@
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package/dist/schemas/tools.d.ts

@@ -0,0 +1,134 @@
+import { z } from "zod";
+export declare const BuscarPorNomeInputSchema: z.ZodObject<{
+    nome: z.ZodString;
+    pagina: z.ZodOptional<z.ZodNumber>;
+    count: z.ZodOptional<z.ZodNumber>;
+}, z.core.$strip>;
+export declare const BuscarPorPrincipioAtivoInputSchema: z.ZodObject<{
+    principioAtivo: z.ZodString;
+    pagina: z.ZodOptional<z.ZodNumber>;
+    count: z.ZodOptional<z.ZodNumber>;
+}, z.core.$strip>;
+export declare const BuscarPorClasseTerapeuticaInputSchema: z.ZodObject<{
+    classeTerapeutica: z.ZodString;
+    pagina: z.ZodOptional<z.ZodNumber>;
+    count: z.ZodOptional<z.ZodNumber>;
+}, z.core.$strip>;
+export declare const FiltrarPorTarjaInputSchema: z.ZodObject<{
+    tarja: z.ZodEnum<{
+        LIVRE: "LIVRE";
+        VERMELHA: "VERMELHA";
+        PRETA: "PRETA";
+    }>;
+    pagina: z.ZodOptional<z.ZodNumber>;
+    count: z.ZodOptional<z.ZodNumber>;
+}, z.core.$strip>;
+export declare const ConsultarBulaInputSchema: z.ZodObject<{
+    numProcesso: z.ZodString;
+}, z.core.$strip>;
+export declare const ListarApresentacoesInputSchema: z.ZodObject<{
+    numProcesso: z.ZodString;
+}, z.core.$strip>;
+export declare const MetaSchema: z.ZodObject<{
+    data_da_base: z.ZodString;
+    fonte: z.ZodString;
+    defasagem_dias: z.ZodNumber;
+    modo: z.ZodEnum<{
+        cache_local: "cache_local";
+        online: "online";
+    }>;
+    status: z.ZodOptional<z.ZodEnum<{
+        stale: "stale";
+        ok: "ok";
+    }>>;
+}, z.core.$strip>;
+export declare const MedicamentoListaOutputSchema: z.ZodObject<{
+    data: z.ZodObject<{
+        total: z.ZodNumber;
+        pagina: z.ZodNumber;
+        medicamentos: z.ZodArray<z.ZodObject<{
+            numProcesso: z.ZodString;
+            nomeProduto: z.ZodString;
+            empresa: z.ZodString;
+            idBulaPacienteProtegido: z.ZodOptional<z.ZodString>;
+            idBulaProfissionalProtegido: z.ZodOptional<z.ZodString>;
+            dataAtualizacao: z.ZodOptional<z.ZodString>;
+        }, z.core.$strip>>;
+    }, z.core.$strip>;
+    _meta: z.ZodObject<{
+        data_da_base: z.ZodString;
+        fonte: z.ZodString;
+        defasagem_dias: z.ZodNumber;
+        modo: z.ZodEnum<{
+            cache_local: "cache_local";
+            online: "online";
+        }>;
+        status: z.ZodOptional<z.ZodEnum<{
+            stale: "stale";
+            ok: "ok";
+        }>>;
+    }, z.core.$strip>;
+}, z.core.$strip>;
+export declare const BulaOutputSchema: z.ZodObject<{
+    data: z.ZodObject<{
+        numProcesso: z.ZodString;
+        nomeProduto: z.ZodString;
+        empresa: z.ZodString;
+        tarja: z.ZodOptional<z.ZodEnum<{
+            LIVRE: "LIVRE";
+            VERMELHA: "VERMELHA";
+            PRETA: "PRETA";
+        }>>;
+        classesTerapeuticas: z.ZodOptional<z.ZodArray<z.ZodString>>;
+        principioAtivo: z.ZodOptional<z.ZodString>;
+        bulaPaciente: z.ZodOptional<z.ZodObject<{
+            id: z.ZodString;
+            urlPdf: z.ZodOptional<z.ZodString>;
+        }, z.core.$strip>>;
+        bulaProfissional: z.ZodOptional<z.ZodObject<{
+            id: z.ZodString;
+            urlPdf: z.ZodOptional<z.ZodString>;
+        }, z.core.$strip>>;
+    }, z.core.$strip>;
+    _meta: z.ZodObject<{
+        data_da_base: z.ZodString;
+        fonte: z.ZodString;
+        defasagem_dias: z.ZodNumber;
+        modo: z.ZodEnum<{
+            cache_local: "cache_local";
+            online: "online";
+        }>;
+        status: z.ZodOptional<z.ZodEnum<{
+            stale: "stale";
+            ok: "ok";
+        }>>;
+    }, z.core.$strip>;
+}, z.core.$strip>;
+export declare const ApresentacoesOutputSchema: z.ZodObject<{
+    data: z.ZodObject<{
+        numProcesso: z.ZodString;
+        nomeProduto: z.ZodString;
+        empresa: z.ZodString;
+        apresentacoes: z.ZodArray<z.ZodObject<{
+            descricao: z.ZodString;
+        }, z.core.$strip>>;
+    }, z.core.$strip>;
+    _meta: z.ZodObject<{
+        data_da_base: z.ZodString;
+        fonte: z.ZodString;
+        defasagem_dias: z.ZodNumber;
+        modo: z.ZodEnum<{
+            cache_local: "cache_local";
+            online: "online";
+        }>;
+        status: z.ZodOptional<z.ZodEnum<{
+            stale: "stale";
+            ok: "ok";
+        }>>;
+    }, z.core.$strip>;
+}, z.core.$strip>;
+export type MedicamentoListaOutput = z.infer<typeof MedicamentoListaOutputSchema>;
+export type BulaOutput = z.infer<typeof BulaOutputSchema>;
+export type ApresentacoesOutput = z.infer<typeof ApresentacoesOutputSchema>;
+export type Meta = z.infer<typeof MetaSchema>;
+//# sourceMappingURL=tools.d.ts.map

package/dist/schemas/tools.d.ts.map

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package/dist/schemas/tools.js

@@ -0,0 +1,106 @@
+import { z } from "zod";
+// ── Inputs ──────────────────────────────────────────────────────────────────
+export const BuscarPorNomeInputSchema = z.object({
+    nome: z.string().min(1).describe("Nome comercial do medicamento"),
+    pagina: z.number().int().min(1).optional().describe("Número da página (padrão: 1)"),
+    count: z
+        .number()
+        .int()
+        .min(1)
+        .max(100)
+        .optional()
+        .describe("Resultados por página (padrão: 10, máx: 100)"),
+});
+export const BuscarPorPrincipioAtivoInputSchema = z.object({
+    principioAtivo: z
+        .string()
+        .min(1)
+        .describe("DCB ou DCI do princípio ativo (ex: dipirona, ibuprofeno)"),
+    pagina: z.number().int().min(1).optional(),
+    count: z.number().int().min(1).max(100).optional(),
+});
+export const BuscarPorClasseTerapeuticaInputSchema = z.object({
+    classeTerapeutica: z
+        .string()
+        .min(1)
+        .describe("Classe terapêutica do medicamento (ex: antibiótico, analgésico)"),
+    pagina: z.number().int().min(1).optional(),
+    count: z.number().int().min(1).max(100).optional(),
+});
+export const FiltrarPorTarjaInputSchema = z.object({
+    tarja: z
+        .enum(["LIVRE", "VERMELHA", "PRETA"])
+        .describe("Tipo de tarja: LIVRE (venda livre), VERMELHA (retenção de receita), PRETA (controle especial)"),
+    pagina: z.number().int().min(1).optional(),
+    count: z.number().int().min(1).max(100).optional(),
+});
+export const ConsultarBulaInputSchema = z.object({
+    numProcesso: z
+        .string()
+        .min(1)
+        .describe("Número de processo do medicamento na ANVISA (obtido via busca de medicamentos)"),
+});
+export const ListarApresentacoesInputSchema = z.object({
+    numProcesso: z.string().min(1).describe("Número de processo do medicamento na ANVISA"),
+});
+// ── Meta ─────────────────────────────────────────────────────────────────────
+export const MetaSchema = z.object({
+    data_da_base: z.string().describe("ISO 8601 da última atualização da base consultada"),
+    fonte: z.string().describe("Identificação da fonte que respondeu (ex: anvisa_api, cache_local)"),
+    defasagem_dias: z.number().describe("Dias desde data_da_base"),
+    modo: z.enum(["cache_local", "online"]),
+    status: z.enum(["ok", "stale"]).optional().describe("'stale' quando defasagem > 30 dias"),
+});
+// ── Shared pieces ────────────────────────────────────────────────────────────
+const MedicamentoResumoSchema = z.object({
+    numProcesso: z.string(),
+    nomeProduto: z.string(),
+    empresa: z.string(),
+    idBulaPacienteProtegido: z.string().optional(),
+    idBulaProfissionalProtegido: z.string().optional(),
+    dataAtualizacao: z.string().optional(),
+});
+// ── Outputs ──────────────────────────────────────────────────────────────────
+export const MedicamentoListaOutputSchema = z.object({
+    data: z.object({
+        total: z.number().describe("Número de resultados retornados nesta página"),
+        pagina: z.number(),
+        medicamentos: z.array(MedicamentoResumoSchema),
+    }),
+    _meta: MetaSchema,
+});
+export const BulaOutputSchema = z.object({
+    data: z.object({
+        numProcesso: z.string(),
+        nomeProduto: z.string(),
+        empresa: z.string(),
+        tarja: z.enum(["LIVRE", "VERMELHA", "PRETA"]).optional(),
+        classesTerapeuticas: z.array(z.string()).optional(),
+        principioAtivo: z.string().optional(),
+        bulaPaciente: z
+            .object({
+            id: z.string(),
+            urlPdf: z.string().optional(),
+        })
+            .optional(),
+        bulaProfissional: z
+            .object({
+            id: z.string(),
+            urlPdf: z.string().optional(),
+        })
+            .optional(),
+    }),
+    _meta: MetaSchema,
+});
+export const ApresentacoesOutputSchema = z.object({
+    data: z.object({
+        numProcesso: z.string(),
+        nomeProduto: z.string(),
+        empresa: z.string(),
+        apresentacoes: z.array(z.object({
+            descricao: z.string(),
+        })),
+    }),
+    _meta: MetaSchema,
+});
+//# sourceMappingURL=tools.js.map

package/dist/schemas/tools.js.map

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package/dist/server.d.ts

@@ -0,0 +1,4 @@
+import { McpServer } from "@modelcontextprotocol/sdk/server/mcp.js";
+import type { IBularioRepository } from "./domain/repository.js";
+export declare function createServer(repository: IBularioRepository): McpServer;
+//# sourceMappingURL=server.d.ts.map

package/dist/server.d.ts.map

@@ -0,0 +1 @@
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package/dist/server.js

@@ -0,0 +1,25 @@
+import { McpServer } from "@modelcontextprotocol/sdk/server/mcp.js";
+import { registerPrompts } from "./prompts/index.js";
+import { registerResources } from "./resources/index.js";
+import { registerBuscarPorClasseTerapeutica } from "./tools/buscar-por-classe-terapeutica.js";
+import { registerBuscarPorNome } from "./tools/buscar-por-nome.js";
+import { registerBuscarPorPrincipioAtivo } from "./tools/buscar-por-principio-ativo.js";
+import { registerConsultarBula } from "./tools/consultar-bula.js";
+import { registerFiltrarPorTarja } from "./tools/filtrar-por-tarja.js";
+import { registerListarApresentacoes } from "./tools/listar-apresentacoes.js";
+export function createServer(repository) {
+    const server = new McpServer({
+        name: "mcpassure-anvisa-bulario",
+        version: "1.0.0",
+    });
+    registerBuscarPorNome(server, repository);
+    registerBuscarPorPrincipioAtivo(server, repository);
+    registerBuscarPorClasseTerapeutica(server, repository);
+    registerFiltrarPorTarja(server, repository);
+    registerConsultarBula(server, repository);
+    registerListarApresentacoes(server, repository);
+    registerPrompts(server, repository);
+    registerResources(server, repository);
+    return server;
+}
+//# sourceMappingURL=server.js.map

package/dist/server.js.map

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package/dist/sources/anvisa-api.d.ts

@@ -0,0 +1,25 @@
+import { type HttpGet } from "../utils/http.js";
+import type { Apresentacao, BulaLink, BularioSource, MedicamentoDetalhes, MedicamentoResumo, SearchByClasseTerapeuticaParams, SearchByNameParams, SearchByPrincipalAtivoParams, SearchByTarjaParams } from "./types.js";
+export declare class AnvisaApiSource implements BularioSource {
+    readonly name = "anvisa_api";
+    private readonly client;
+    /**
+     * @param baseUrl URL base da API ANVISA (ex: https://consultas.anvisa.gov.br)
+     * @param maxRetries Tentativas de retry em falhas transitórias
+     * @param baseDelayMs Delay base do backoff exponencial
+     * @param timeoutMs Timeout por request em ms
+     * @param client Opcional — HttpClient pré-construído. Útil pra testes (mock)
+     *               e pra compartilhar browser entre múltiplos sources.
+     */
+    constructor(baseUrl: string, maxRetries: number, baseDelayMs: number, timeoutMs: number, client?: HttpGet);
+    close(): Promise<void>;
+    searchByName(params: SearchByNameParams): Promise<MedicamentoResumo[]>;
+    searchByPrincipalAtivo(params: SearchByPrincipalAtivoParams): Promise<MedicamentoResumo[]>;
+    searchByClasseTerapeutica(params: SearchByClasseTerapeuticaParams): Promise<MedicamentoResumo[]>;
+    searchByTarja(params: SearchByTarjaParams): Promise<MedicamentoResumo[]>;
+    getDetalhes(numProcesso: string): Promise<MedicamentoDetalhes>;
+    getApresentacoes(numProcesso: string): Promise<Apresentacao[]>;
+    getBulaLink(idBulaProtegido: string): Promise<BulaLink>;
+    private _search;
+}
+//# sourceMappingURL=anvisa-api.d.ts.map

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