@mcpassure/mcp-anvisa-bulario 0.0.1 → 0.1.0

package/dist/domain/repository.js

@@ -0,0 +1,88 @@
+import { DEFAULT_TTLS } from "../cache/types.js";
+import { buildMeta } from "../utils/meta.js";
+export class AllSourcesFailedError extends Error {
+    failures;
+    constructor(failures) {
+        const detail = failures.map((f) => `${f.source}: ${f.error.message}`).join("; ");
+        super(`Todas as fontes falharam. ${detail}`);
+        this.name = "AllSourcesFailedError";
+        this.failures = failures;
+    }
+}
+export class BularioRepository {
+    cache;
+    sources;
+    degradedThresholdDays;
+    constructor(cache, sources, degradedThresholdDays = 30) {
+        this.cache = cache;
+        this.sources = sources;
+        this.degradedThresholdDays = degradedThresholdDays;
+    }
+    async searchByName(params) {
+        const key = `search:name:${params.nome.toLowerCase().trim()}:${params.pagina ?? 1}:${params.count ?? 10}`;
+        return this._withCache(key, DEFAULT_TTLS.searchResults, (src) => src.searchByName(params));
+    }
+    async searchByPrincipalAtivo(params) {
+        const key = `search:pa:${params.principioAtivo.toLowerCase().trim()}:${params.pagina ?? 1}:${params.count ?? 10}`;
+        return this._withCache(key, DEFAULT_TTLS.searchResults, (src) => src.searchByPrincipalAtivo(params));
+    }
+    async searchByClasseTerapeutica(params) {
+        const key = `search:ct:${params.classeTerapeutica.toLowerCase().trim()}:${params.pagina ?? 1}:${params.count ?? 10}`;
+        return this._withCache(key, DEFAULT_TTLS.searchResults, (src) => src.searchByClasseTerapeutica(params));
+    }
+    async searchByTarja(params) {
+        const key = `search:tarja:${params.tarja}:${params.pagina ?? 1}:${params.count ?? 10}`;
+        return this._withCache(key, DEFAULT_TTLS.searchResults, (src) => src.searchByTarja(params));
+    }
+    async getDetalhes(numProcesso) {
+        const key = `medicamento:${numProcesso}`;
+        return this._withCache(key, DEFAULT_TTLS.medicamentoDetalhes, (src) => src.getDetalhes(numProcesso));
+    }
+    async getApresentacoes(numProcesso) {
+        const key = `apresentacoes:${numProcesso}`;
+        return this._withCache(key, DEFAULT_TTLS.medicamentoDetalhes, (src) => src.getApresentacoes(numProcesso));
+    }
+    async getBulaLink(idBulaProtegido) {
+        const key = `bula:link:${idBulaProtegido}`;
+        return this._withCache(key, DEFAULT_TTLS.bulaLink, (src) => src.getBulaLink(idBulaProtegido));
+    }
+    async _withCache(key, ttlSeconds, fetch) {
+        const cached = this.cache.get(key);
+        if (cached) {
+            return {
+                data: cached.value,
+                _meta: buildMeta({
+                    dataBase: cached.data_da_base,
+                    fonte: "cache_local",
+                    modo: "cache_local",
+                    degradedThresholdDays: this.degradedThresholdDays,
+                }),
+            };
+        }
+        const failures = [];
+        for (const source of this.sources) {
+            try {
+                const data = await fetch(source);
+                const dataBase = new Date().toISOString();
+                this.cache.set(key, data, ttlSeconds, dataBase);
+                return {
+                    data,
+                    _meta: buildMeta({
+                        dataBase,
+                        fonte: source.name,
+                        modo: "online",
+                        degradedThresholdDays: this.degradedThresholdDays,
+                    }),
+                };
+            }
+            catch (err) {
+                failures.push({
+                    source: source.name,
+                    error: err instanceof Error ? err : new Error(String(err)),
+                });
+            }
+        }
+        throw new AllSourcesFailedError(failures);
+    }
+}
+//# sourceMappingURL=repository.js.map

package/dist/domain/repository.js.map

@@ -0,0 +1 @@
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package/dist/domain/types.d.ts

@@ -0,0 +1,2 @@
+export type { Apresentacao, BulaLink, MedicamentoDetalhes, MedicamentoResumo, SearchByClasseTerapeuticaParams, SearchByNameParams, SearchByPrincipalAtivoParams, SearchByTarjaParams, SearchParams, Tarja, } from "../sources/types.js";
+//# sourceMappingURL=types.d.ts.map

package/dist/domain/types.d.ts.map

@@ -0,0 +1 @@
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package/dist/domain/types.js

@@ -0,0 +1,2 @@
+export {};
+//# sourceMappingURL=types.js.map

package/dist/domain/types.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"types.js","sourceRoot":"","sources":["../../src/domain/types.ts"],"names":[],"mappings":""}

package/dist/index.d.ts

@@ -0,0 +1,3 @@
+#!/usr/bin/env node
+export {};
+//# sourceMappingURL=index.d.ts.map

package/dist/index.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"index.d.ts","sourceRoot":"","sources":["../src/index.ts"],"names":[],"mappings":""}

package/dist/index.js

@@ -0,0 +1,37 @@
+#!/usr/bin/env node
+import { StdioServerTransport } from "@modelcontextprotocol/sdk/server/stdio.js";
+import { SqliteCache } from "./cache/sqlite-cache.js";
+import { loadConfig } from "./config.js";
+import { BularioRepository } from "./domain/repository.js";
+import { createServer } from "./server.js";
+import { AnvisaApiSource } from "./sources/anvisa-api.js";
+async function main() {
+    const config = loadConfig();
+    const cache = new SqliteCache(config.cachePath);
+    const sources = [
+        new AnvisaApiSource(config.anvisaBaseUrl, config.maxRetries, config.baseDelayMs, config.requestTimeoutMs),
+        // v1.1+: new AnvisaDadosAbertosSource(config),
+        // v1.2+: new AnvisaPortalBularioSource(config),
+    ];
+    const repository = new BularioRepository(cache, sources);
+    const server = createServer(repository);
+    const transport = new StdioServerTransport();
+    async function shutdown() {
+        // Fecha sources que têm recursos vivos (Playwright browser, etc.)
+        await Promise.allSettled(sources.map((s) => s.close?.()));
+        cache.close();
+        process.exit(0);
+    }
+    process.on("SIGINT", () => {
+        void shutdown();
+    });
+    process.on("SIGTERM", () => {
+        void shutdown();
+    });
+    await server.connect(transport);
+}
+main().catch((err) => {
+    process.stderr.write(`Fatal error: ${err instanceof Error ? err.message : String(err)}\n`);
+    process.exit(1);
+});
+//# sourceMappingURL=index.js.map

package/dist/index.js.map

@@ -0,0 +1 @@
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package/dist/prompts/handlers.d.ts

@@ -0,0 +1,24 @@
+import type { IBularioRepository } from "../domain/repository.js";
+import type { AnalisarApresentacoesInputType, CompararTarjasPorClasseInputType, VerificarMedicamentoCompletoInputType } from "./schemas.js";
+export declare function handleVerificarMedicamentoCompleto(input: VerificarMedicamentoCompletoInputType, repository: IBularioRepository): Promise<Array<{
+    role: "user" | "assistant";
+    content: {
+        type: "text";
+        text: string;
+    };
+}>>;
+export declare function handleCompararTarjasPorClasse(input: CompararTarjasPorClasseInputType, repository: IBularioRepository): Promise<Array<{
+    role: "user" | "assistant";
+    content: {
+        type: "text";
+        text: string;
+    };
+}>>;
+export declare function handleAnalisarApresentacoes(input: AnalisarApresentacoesInputType, repository: IBularioRepository): Promise<Array<{
+    role: "user" | "assistant";
+    content: {
+        type: "text";
+        text: string;
+    };
+}>>;
+//# sourceMappingURL=handlers.d.ts.map

package/dist/prompts/handlers.d.ts.map

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package/dist/prompts/handlers.js

@@ -0,0 +1,267 @@
+const DISCLAIMER = "\n\n⚠️ **Aviso ANVISA:** Informações de consulta oficial. Decisões clínicas ou regulatórias " +
+    "devem ser baseadas na fonte ANVISA atualizada. Medicamentos sob Tarja Preta estão sujeitos " +
+    "à Portaria 344/98 — controle especial obrigatório.";
+export async function handleVerificarMedicamentoCompleto(input, repository) {
+    const { termo, incluir_apresentacoes, incluir_bula } = input;
+    let medicamentos = [];
+    let fonteUsada = "";
+    try {
+        const result = await repository.searchByName({ nome: termo, count: 5 });
+        medicamentos = result.data;
+        fonteUsada = "buscar_por_nome";
+    }
+    catch {
+        try {
+            const result = await repository.searchByPrincipalAtivo({ principioAtivo: termo, count: 5 });
+            medicamentos = result.data;
+            fonteUsada = "buscar_por_principio_ativo";
+        }
+        catch (err) {
+            const message = err instanceof Error ? err.message : String(err);
+            return [
+                {
+                    role: "assistant",
+                    content: {
+                        type: "text",
+                        text: `Não foi possível localizar medicamentos para o termo "${termo}": ${message}${DISCLAIMER}`,
+                    },
+                },
+            ];
+        }
+    }
+    if (medicamentos.length === 0) {
+        return [
+            {
+                role: "assistant",
+                content: {
+                    type: "text",
+                    text: `Nenhum medicamento encontrado para o termo "${termo}" no Bulário ANVISA.${DISCLAIMER}`,
+                },
+            },
+        ];
+    }
+    const sections = [
+        `## Medicamentos encontrados para "${termo}" (via ${fonteUsada})`,
+        `Total de resultados: ${medicamentos.length}`,
+    ];
+    for (const med of medicamentos) {
+        const linhas = [
+            `\n### ${med.nomeProduto}`,
+            `- **Empresa:** ${med.empresa}`,
+            `- **Nº Processo ANVISA:** ${med.numProcesso}`,
+        ];
+        if (med.dataAtualizacao)
+            linhas.push(`- **Última atualização:** ${med.dataAtualizacao}`);
+        if (incluir_apresentacoes && med.numProcesso) {
+            try {
+                const ap = await repository.getApresentacoes(med.numProcesso);
+                if (ap.data.length > 0) {
+                    linhas.push(`- **Apresentações (${ap.data.length}):**`);
+                    for (const a of ap.data.slice(0, 5)) {
+                        linhas.push(`  - ${a.descricao}`);
+                    }
+                    if (ap.data.length > 5)
+                        linhas.push(`  - ... (+${ap.data.length - 5} apresentações)`);
+                }
+            }
+            catch {
+                linhas.push(`- **Apresentações:** não disponível`);
+            }
+        }
+        if (incluir_bula && med.idBulaPacienteProtegido) {
+            try {
+                const bula = await repository.getBulaLink(med.idBulaPacienteProtegido);
+                if (bula.data.urlPdf) {
+                    linhas.push(`- **Bula (paciente):** ${bula.data.urlPdf}`);
+                }
+            }
+            catch {
+                linhas.push(`- **Bula:** não disponível`);
+            }
+        }
+        sections.push(linhas.join("\n"));
+    }
+    sections.push(DISCLAIMER);
+    return [
+        {
+            role: "user",
+            content: { type: "text", text: `Verificar medicamento: ${termo}` },
+        },
+        {
+            role: "assistant",
+            content: { type: "text", text: sections.join("\n") },
+        },
+    ];
+}
+export async function handleCompararTarjasPorClasse(input, repository) {
+    const { classe_terapeutica, limite } = input;
+    let medicamentos = [];
+    try {
+        const result = await repository.searchByClasseTerapeutica({
+            classeTerapeutica: classe_terapeutica,
+            count: limite,
+        });
+        medicamentos = result.data;
+    }
+    catch (err) {
+        const message = err instanceof Error ? err.message : String(err);
+        return [
+            {
+                role: "assistant",
+                content: {
+                    type: "text",
+                    text: `Erro ao buscar classe terapêutica "${classe_terapeutica}": ${message}${DISCLAIMER}`,
+                },
+            },
+        ];
+    }
+    const grupos = {
+        LIVRE: [],
+        VERMELHA: [],
+        PRETA: [],
+        DESCONHECIDA: [],
+    };
+    for (const med of medicamentos) {
+        if (med.numProcesso) {
+            try {
+                const det = await repository.getDetalhes(med.numProcesso);
+                const tarja = det.data.tarja ?? "DESCONHECIDA";
+                const grupo = tarja in grupos ? tarja : "DESCONHECIDA";
+                grupos[grupo].push(med.nomeProduto);
+            }
+            catch {
+                grupos.DESCONHECIDA.push(med.nomeProduto);
+            }
+        }
+    }
+    const total = medicamentos.length;
+    const lines = [
+        `## Classe Terapêutica: ${classe_terapeutica}`,
+        `**Total analisado:** ${total} medicamento(s)`,
+        "",
+        `- **Sem Tarja (Venda Livre):** ${grupos.LIVRE.length}`,
+        `- **Tarja Amarela (controle leve/antibióticos):** — *não categorizado pelo Bulário ANVISA*`,
+        `- **Tarja Vermelha (prescrição obrigatória):** ${grupos.VERMELHA.length}`,
+        `- **Tarja Preta (controle especial — Portaria 344/98):** ${grupos.PRETA.length}`,
+        `- **Não categorizado:** ${grupos.DESCONHECIDA.length}`,
+    ];
+    if (grupos.PRETA.length > 0) {
+        lines.push("", `⚠️ **Tarja Preta identificados (${grupos.PRETA.length}):** ${grupos.PRETA.slice(0, 10).join(", ")}`);
+    }
+    lines.push(DISCLAIMER);
+    return [
+        {
+            role: "user",
+            content: {
+                type: "text",
+                text: `Comparar tarjas para classe terapêutica: ${classe_terapeutica}`,
+            },
+        },
+        {
+            role: "assistant",
+            content: { type: "text", text: lines.join("\n") },
+        },
+    ];
+}
+export async function handleAnalisarApresentacoes(input, repository) {
+    const { nome_medicamento, agrupar_por } = input;
+    let medicamentos = [];
+    try {
+        const result = await repository.searchByName({ nome: nome_medicamento, count: 10 });
+        medicamentos = result.data;
+    }
+    catch (err) {
+        const message = err instanceof Error ? err.message : String(err);
+        return [
+            {
+                role: "assistant",
+                content: {
+                    type: "text",
+                    text: `Erro ao buscar "${nome_medicamento}": ${message}${DISCLAIMER}`,
+                },
+            },
+        ];
+    }
+    if (medicamentos.length === 0) {
+        return [
+            {
+                role: "assistant",
+                content: {
+                    type: "text",
+                    text: `Nenhum medicamento encontrado para "${nome_medicamento}".${DISCLAIMER}`,
+                },
+            },
+        ];
+    }
+    const agrupado = {};
+    for (const med of medicamentos.slice(0, 5)) {
+        if (!med.numProcesso)
+            continue;
+        try {
+            const apResult = await repository.getApresentacoes(med.numProcesso);
+            for (const ap of apResult.data) {
+                let chave = "Outros";
+                const desc = ap.descricao ?? "";
+                if (agrupar_por === "concentracao") {
+                    const match = desc.match(/\d+[\s,.]?\d*\s*(mg|mcg|g|ml|%|UI|mEq)/i);
+                    chave = match ? match[0].trim() : "Concentração não identificada";
+                }
+                else if (agrupar_por === "forma_farmaceutica") {
+                    const formas = [
+                        "comprimido",
+                        "cápsula",
+                        "xarope",
+                        "solução",
+                        "injetável",
+                        "pomada",
+                        "gel",
+                        "spray",
+                        "supositório",
+                        "adesivo",
+                    ];
+                    const forma = formas.find((f) => desc.toLowerCase().includes(f));
+                    chave = forma ? forma.charAt(0).toUpperCase() + forma.slice(1) : "Forma não identificada";
+                }
+                else if (agrupar_por === "fabricante") {
+                    chave = med.empresa ?? "Fabricante desconhecido";
+                }
+                if (!agrupado[chave])
+                    agrupado[chave] = [];
+                agrupado[chave].push(`${med.nomeProduto} — ${desc}`);
+            }
+        }
+        catch {
+            // ignora erros individuais de apresentações
+        }
+    }
+    const totalApresentacoes = Object.values(agrupado).flat().length;
+    const lines = [
+        `## Apresentações de "${nome_medicamento}" agrupadas por ${agrupar_por}`,
+        `**Total de apresentações analisadas:** ${totalApresentacoes}`,
+        "",
+    ];
+    for (const [grupo, items] of Object.entries(agrupado).sort()) {
+        lines.push(`### ${grupo} (${items.length})`);
+        for (const item of items.slice(0, 5)) {
+            lines.push(`- ${item}`);
+        }
+        if (items.length > 5)
+            lines.push(`- ... (+${items.length - 5} itens)`);
+        lines.push("");
+    }
+    lines.push(DISCLAIMER);
+    return [
+        {
+            role: "user",
+            content: {
+                type: "text",
+                text: `Analisar apresentações de ${nome_medicamento} agrupando por ${agrupar_por}`,
+            },
+        },
+        {
+            role: "assistant",
+            content: { type: "text", text: lines.join("\n") },
+        },
+    ];
+}
+//# sourceMappingURL=handlers.js.map

package/dist/prompts/handlers.js.map

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package/dist/prompts/index.d.ts

@@ -0,0 +1,4 @@
+import type { McpServer } from "@modelcontextprotocol/sdk/server/mcp.js";
+import type { IBularioRepository } from "../domain/repository.js";
+export declare function registerPrompts(server: McpServer, repository: IBularioRepository): void;
+//# sourceMappingURL=index.d.ts.map

package/dist/prompts/index.d.ts.map

@@ -0,0 +1 @@
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package/dist/prompts/index.js

@@ -0,0 +1,35 @@
+import { handleAnalisarApresentacoes, handleCompararTarjasPorClasse, handleVerificarMedicamentoCompleto, } from "./handlers.js";
+import { AnalisarApresentacoesInput, CompararTarjasPorClasseInput, VerificarMedicamentoCompletoInput, } from "./schemas.js";
+export function registerPrompts(server, repository) {
+    server.registerPrompt("verificar_medicamento_completo", {
+        title: "Verificar Medicamento Completo",
+        description: "Consolida nome, princípio ativo, classe terapêutica, tarja, apresentações e (opcional) bula " +
+            "para um termo de busca. Tenta busca por nome e fallback por princípio ativo.",
+        argsSchema: VerificarMedicamentoCompletoInput.shape,
+    }, async (args) => {
+        const parsed = VerificarMedicamentoCompletoInput.parse(args);
+        const messages = await handleVerificarMedicamentoCompleto(parsed, repository);
+        return { messages };
+    });
+    server.registerPrompt("comparar_tarjas_por_classe", {
+        title: "Comparar Tarjas por Classe Terapêutica",
+        description: "Agrupa medicamentos de uma classe terapêutica por tarja regulatória. " +
+            "Útil para entender o perfil de prescrição e controle de uma classe.",
+        argsSchema: CompararTarjasPorClasseInput.shape,
+    }, async (args) => {
+        const parsed = CompararTarjasPorClasseInput.parse(args);
+        const messages = await handleCompararTarjasPorClasse(parsed, repository);
+        return { messages };
+    });
+    server.registerPrompt("analisar_apresentacoes", {
+        title: "Analisar Apresentações de Medicamento",
+        description: "Agrupa as apresentações comerciais de um medicamento por concentração, " +
+            "forma farmacêutica ou fabricante.",
+        argsSchema: AnalisarApresentacoesInput.shape,
+    }, async (args) => {
+        const parsed = AnalisarApresentacoesInput.parse(args);
+        const messages = await handleAnalisarApresentacoes(parsed, repository);
+        return { messages };
+    });
+}
+//# sourceMappingURL=index.js.map

package/dist/prompts/index.js.map

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package/dist/prompts/schemas.d.ts

@@ -0,0 +1,22 @@
+import { z } from "zod";
+export declare const VerificarMedicamentoCompletoInput: z.ZodObject<{
+    termo: z.ZodString;
+    incluir_apresentacoes: z.ZodDefault<z.ZodBoolean>;
+    incluir_bula: z.ZodDefault<z.ZodBoolean>;
+}, z.core.$strip>;
+export type VerificarMedicamentoCompletoInputType = z.infer<typeof VerificarMedicamentoCompletoInput>;
+export declare const CompararTarjasPorClasseInput: z.ZodObject<{
+    classe_terapeutica: z.ZodString;
+    limite: z.ZodDefault<z.ZodNumber>;
+}, z.core.$strip>;
+export type CompararTarjasPorClasseInputType = z.infer<typeof CompararTarjasPorClasseInput>;
+export declare const AnalisarApresentacoesInput: z.ZodObject<{
+    nome_medicamento: z.ZodString;
+    agrupar_por: z.ZodDefault<z.ZodEnum<{
+        concentracao: "concentracao";
+        forma_farmaceutica: "forma_farmaceutica";
+        fabricante: "fabricante";
+    }>>;
+}, z.core.$strip>;
+export type AnalisarApresentacoesInputType = z.infer<typeof AnalisarApresentacoesInput>;
+//# sourceMappingURL=schemas.d.ts.map

package/dist/prompts/schemas.d.ts.map

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package/dist/prompts/schemas.js

@@ -0,0 +1,15 @@
+import { z } from "zod";
+export const VerificarMedicamentoCompletoInput = z.object({
+    termo: z.string().min(2, "Nome comercial, princípio ativo ou parte"),
+    incluir_apresentacoes: z.boolean().default(true),
+    incluir_bula: z.boolean().default(false).describe("Se true, inclui resumo da bula (mais caro)"),
+});
+export const CompararTarjasPorClasseInput = z.object({
+    classe_terapeutica: z.string().min(3),
+    limite: z.number().int().min(1).max(100).default(50),
+});
+export const AnalisarApresentacoesInput = z.object({
+    nome_medicamento: z.string().min(2),
+    agrupar_por: z.enum(["concentracao", "forma_farmaceutica", "fabricante"]).default("concentracao"),
+});
+//# sourceMappingURL=schemas.js.map

package/dist/prompts/schemas.js.map

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package/dist/resources/handlers.d.ts

@@ -0,0 +1,5 @@
+import type { IBularioRepository } from "../domain/repository.js";
+export declare const TARJAS_JSON: string;
+export declare function getClassesTerapeuticasJson(_repository: IBularioRepository): Promise<string>;
+export declare const SCOPE_MARKDOWN = "# Escopo do MCP @mcpassure/mcp-anvisa-bulario\n\n## \uD83C\uDDE7\uD83C\uDDF7 Portugu\u00EAs (BR)\n\n### O que este MCP faz\n\nConsulta ao **Bul\u00E1rio Eletr\u00F4nico da ANVISA** (Ag\u00EAncia Nacional de Vigil\u00E2ncia Sanit\u00E1ria), incluindo:\n\n- Busca de medicamentos por nome comercial, princ\u00EDpio ativo, classe terap\u00EAutica ou tarja\n- Recupera\u00E7\u00E3o de bulas (paciente e profissional) em PDF via n\u00FAmero de registro ANVISA\n- Listagem de apresenta\u00E7\u00F5es comerciais (concentra\u00E7\u00E3o, forma farmac\u00EAutica, fabricante)\n- Filtragem por tarja regulat\u00F3ria (Livre, Vermelha, Preta)\n- Transport Playwright resistente a prote\u00E7\u00E3o Cloudflare do portal ANVISA\n- Cache local SQLite para redu\u00E7\u00E3o de lat\u00EAncia e requisi\u00E7\u00F5es repetidas\n\n### O que este MCP N\u00C3O faz\n\n- \u274C N\u00E3o substitui consulta direta \u00E0 ANVISA para fins regulat\u00F3rios oficiais\n- \u274C N\u00E3o fornece pre\u00E7os de medicamentos (consulte CMED/ANVISA)\n- \u274C N\u00E3o verifica intera\u00E7\u00F5es medicamentosas\n- \u274C N\u00E3o emite receitas ou laudos m\u00E9dicos\n- \u274C N\u00E3o cobre medicamentos fitoter\u00E1picos, cosm\u00E9ticos ou saneantes\n- \u274C N\u00E3o acessa dados de farmacovigil\u00E2ncia ou notifica\u00E7\u00F5es de eventos adversos\n\n### \u26A0\uFE0F Disclaimer regulat\u00F3rio\n\nDados obtidos do Bul\u00E1rio Eletr\u00F4nico ANVISA com lat\u00EAncia de cache configur\u00E1vel.\n**Decis\u00F5es cl\u00EDnicas ou regulat\u00F3rias devem sempre utilizar a fonte ANVISA oficial e atualizada.**\n\nMedicamentos sob **Tarja Preta** (Portaria SVS/MS 344/1998) est\u00E3o sujeitos a controle especial \u2014\npsicotr\u00F3picos, entorpecentes, precursores e outras subst\u00E2ncias de controle especial.\nO uso inadequado \u00E9 crime previsto em lei.\n\n---\n\n## \uD83C\uDDFA\uD83C\uDDF8 English\n\n### What this MCP does\n\nQueries the **ANVISA Electronic Drug Information Database** (Brazilian Health Regulatory Agency), including:\n\n- Search medications by trade name, active ingredient (INN/DCB), therapeutic class, or controlled-substance tier\n- Retrieve patient and prescriber leaflets (bulas) in PDF via ANVISA registration number\n- List commercial presentations (dosage, pharmaceutical form, manufacturer)\n- Filter by regulatory tier (Sem Tarja/OTC, Tarja Vermelha/Rx, Tarja Preta/controlled)\n- Cloudflare-resistant Playwright transport for the ANVISA portal\n- Local SQLite cache to reduce latency on repeated queries\n\n### What this MCP does NOT do\n\n- \u274C Does not replace official ANVISA consultation for regulatory compliance\n- \u274C Does not provide drug pricing (see CMED/ANVISA)\n- \u274C Does not check drug interactions\n- \u274C Does not issue prescriptions or medical reports\n- \u274C Does not cover phytotherapeutics, cosmetics, or sanitizers\n- \u274C Does not access pharmacovigilance data or adverse event reports\n\n### \u26A0\uFE0F Regulatory disclaimer\n\nData sourced from the ANVISA Electronic Drug Information Database with configurable cache latency.\n**Clinical or regulatory decisions must always use the official and up-to-date ANVISA source.**\n\nMedications classified as **Tarja Preta** (Black-banded \u2014 controlled substance under Brazilian\nOrdinance SVS/MS 344/1998) are subject to special control \u2014 psychotropics, narcotics, precursors,\nand other controlled substances. Misuse is a criminal offense under Brazilian law.\n";
+//# sourceMappingURL=handlers.d.ts.map

package/dist/resources/handlers.d.ts.map

@@ -0,0 +1 @@
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