@inflexa-ai/harness 0.35.8 → 0.36.0

package/dist/workflows/target-assessment/steps/phase2-aggregate.d.ts

@@ -1,657 +0,0 @@
-/**
- * Phase 2 aggregator — schema definitions retained for downstream
- * type-checking. The DBOS workflow assembles the Phase-2 bundle inline.
- *
- * The `failedTrialClassifier` and `offTargetCurator` keys present in
- * earlier versions were removed as part of the
- * `target-dossier-deep-synthesis` change — those steps were no-ops; their
- * deterministic logic runs in Phase 4 (`classifyFailureReason`,
- * `aggregateOffTargetPanel`). The bundle continues to expose them as
- * coverage-tagged stubs so downstream code that still reads them
- * compiles, but nothing populates them.
- */
-import { z } from "zod";
-export declare const Phase2BundleSchema: z.ZodObject<{
-    phase1: z.ZodObject<{
-        resolved: z.ZodObject<{
-            assessmentId: z.ZodString;
-            goal: z.ZodNullable<z.ZodString>;
-            canonicalId: z.ZodString;
-            canonicalOntology: z.ZodEnum<{
-                hgnc: "hgnc";
-                ensembl: "ensembl";
-            }>;
-            geneSymbol: z.ZodString;
-            approvedName: z.ZodString;
-            ids: z.ZodObject<{
-                hgnc: z.ZodNullable<z.ZodString>;
-                ensembl: z.ZodNullable<z.ZodString>;
-                uniprot: z.ZodNullable<z.ZodString>;
-                chembl: z.ZodNullable<z.ZodString>;
-                entrez: z.ZodNullable<z.ZodString>;
-            }, z.core.$strip>;
-            synonyms: z.ZodArray<z.ZodString>;
-            proteinSynonyms: z.ZodArray<z.ZodString>;
-            proteinFamily: z.ZodNullable<z.ZodString>;
-            resolutionCoverage: z.ZodObject<{
-                hgnc: z.ZodBoolean;
-                uniprot: z.ZodBoolean;
-                ensembl: z.ZodBoolean;
-                chembl: z.ZodBoolean;
-            }, z.core.$strip>;
-        }, z.core.$strip>;
-        collectors: z.ZodObject<{
-            opentargets: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    ensemblId: z.ZodString;
-                    approvedSymbol: z.ZodString;
-                    approvedName: z.ZodString;
-                    tractability: z.ZodNullable<z.ZodObject<{
-                        smallMolecule: z.ZodNullable<z.ZodBoolean>;
-                        antibody: z.ZodNullable<z.ZodBoolean>;
-                        otherModalities: z.ZodNullable<z.ZodBoolean>;
-                    }, z.core.$strip>>;
-                    associations: z.ZodArray<z.ZodObject<{
-                        diseaseId: z.ZodString;
-                        diseaseName: z.ZodString;
-                        score: z.ZodNumber;
-                        geneticAssociationScore: z.ZodNullable<z.ZodNumber>;
-                        knownDrugScore: z.ZodNullable<z.ZodNumber>;
-                        literatureScore: z.ZodNullable<z.ZodNumber>;
-                        animalModelScore: z.ZodDefault<z.ZodNullable<z.ZodNumber>>;
-                        somaticMutationScore: z.ZodDefault<z.ZodNullable<z.ZodNumber>>;
-                        literaturePmids: z.ZodDefault<z.ZodArray<z.ZodString>>;
-                    }, z.core.$strip>>;
-                    safetyLiabilities: z.ZodArray<z.ZodObject<{
-                        event: z.ZodString;
-                        biosamples: z.ZodArray<z.ZodString>;
-                        effects: z.ZodNullable<z.ZodString>;
-                        source: z.ZodString;
-                    }, z.core.$strip>>;
-                    baselineExpression: z.ZodArray<z.ZodObject<{
-                        tissueId: z.ZodString;
-                        tissueLabel: z.ZodString;
-                        organSystem: z.ZodNullable<z.ZodString>;
-                        datasourceId: z.ZodString;
-                        rna: z.ZodNullable<z.ZodObject<{
-                            value: z.ZodNumber;
-                            unit: z.ZodString;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            chemblModulators: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    targetChemblId: z.ZodNullable<z.ZodString>;
-                    modulators: z.ZodArray<z.ZodObject<{
-                        moleculeChemblId: z.ZodString;
-                        parentChemblId: z.ZodNullable<z.ZodString>;
-                        preferredName: z.ZodNullable<z.ZodString>;
-                        maxPhase: z.ZodNullable<z.ZodNumber>;
-                        moleculeType: z.ZodNullable<z.ZodString>;
-                        firstApproval: z.ZodNullable<z.ZodNumber>;
-                        evidence_source: z.ZodOptional<z.ZodLiteral<"chembl_activity">>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            ctgov: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    active: z.ZodArray<z.ZodObject<{
-                        nctId: z.ZodString;
-                        title: z.ZodString;
-                        officialTitle: z.ZodNullable<z.ZodString>;
-                        status: z.ZodString;
-                        phase: z.ZodNullable<z.ZodString>;
-                        studyType: z.ZodNullable<z.ZodString>;
-                        primaryPurpose: z.ZodNullable<z.ZodString>;
-                        conditions: z.ZodArray<z.ZodString>;
-                        interventions: z.ZodArray<z.ZodString>;
-                        interventionDetails: z.ZodArray<z.ZodObject<{
-                            name: z.ZodString;
-                            type: z.ZodNullable<z.ZodString>;
-                            description: z.ZodNullable<z.ZodString>;
-                            otherNames: z.ZodArray<z.ZodString>;
-                        }, z.core.$strip>>;
-                        enrollmentCount: z.ZodNullable<z.ZodNumber>;
-                        startDate: z.ZodNullable<z.ZodString>;
-                        primaryCompletionDate: z.ZodNullable<z.ZodString>;
-                        whyStopped: z.ZodNullable<z.ZodString>;
-                        briefSummary: z.ZodNullable<z.ZodString>;
-                        detailedDescription: z.ZodNullable<z.ZodString>;
-                        sponsor: z.ZodNullable<z.ZodString>;
-                        collection_query: z.ZodOptional<z.ZodString>;
-                        collection_channel: z.ZodOptional<z.ZodEnum<{
-                            class_modulator: "class_modulator";
-                            target_symbol: "target_symbol";
-                            therapeutic_program: "therapeutic_program";
-                            biomarker_context: "biomarker_context";
-                            failed_intervention: "failed_intervention";
-                        }>>;
-                    }, z.core.$strip>>;
-                    failed: z.ZodArray<z.ZodObject<{
-                        nctId: z.ZodString;
-                        title: z.ZodString;
-                        officialTitle: z.ZodNullable<z.ZodString>;
-                        status: z.ZodString;
-                        phase: z.ZodNullable<z.ZodString>;
-                        studyType: z.ZodNullable<z.ZodString>;
-                        primaryPurpose: z.ZodNullable<z.ZodString>;
-                        conditions: z.ZodArray<z.ZodString>;
-                        interventions: z.ZodArray<z.ZodString>;
-                        interventionDetails: z.ZodArray<z.ZodObject<{
-                            name: z.ZodString;
-                            type: z.ZodNullable<z.ZodString>;
-                            description: z.ZodNullable<z.ZodString>;
-                            otherNames: z.ZodArray<z.ZodString>;
-                        }, z.core.$strip>>;
-                        enrollmentCount: z.ZodNullable<z.ZodNumber>;
-                        startDate: z.ZodNullable<z.ZodString>;
-                        primaryCompletionDate: z.ZodNullable<z.ZodString>;
-                        whyStopped: z.ZodNullable<z.ZodString>;
-                        briefSummary: z.ZodNullable<z.ZodString>;
-                        detailedDescription: z.ZodNullable<z.ZodString>;
-                        sponsor: z.ZodNullable<z.ZodString>;
-                        collection_query: z.ZodOptional<z.ZodString>;
-                        collection_channel: z.ZodOptional<z.ZodEnum<{
-                            class_modulator: "class_modulator";
-                            target_symbol: "target_symbol";
-                            therapeutic_program: "therapeutic_program";
-                            biomarker_context: "biomarker_context";
-                            failed_intervention: "failed_intervention";
-                        }>>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            faersByTarget: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    drugProbed: z.ZodString;
-                    totalReports: z.ZodNullable<z.ZodNumber>;
-                    topReactions: z.ZodArray<z.ZodObject<{
-                        reaction: z.ZodString;
-                        count: z.ZodNumber;
-                    }, z.core.$strip>>;
-                    seriousness: z.ZodNullable<z.ZodObject<{
-                        totalReports: z.ZodNumber;
-                        fatalCount: z.ZodNumber;
-                        hospitalizationCount: z.ZodNumber;
-                        lifeThreateningCount: z.ZodNumber;
-                        disablingCount: z.ZodNumber;
-                        congenitalAnomalyCount: z.ZodDefault<z.ZodNumber>;
-                        otherSeriousCount: z.ZodDefault<z.ZodNumber>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            expressionHuman: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    source: z.ZodEnum<{
-                        gtex: "gtex";
-                        hpa_consensus: "hpa_consensus";
-                        hpa_rna_tissue: "hpa_rna_tissue";
-                    }>;
-                    unit: z.ZodEnum<{
-                        tpm: "tpm";
-                        ntpm: "ntpm";
-                        consensus_normalized: "consensus_normalized";
-                    }>;
-                    normalization_notes: z.ZodString;
-                    tissues: z.ZodArray<z.ZodObject<{
-                        tissueLabel: z.ZodString;
-                        organSystem: z.ZodNullable<z.ZodString>;
-                        value: z.ZodNullable<z.ZodNumber>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            expressionMultiSpecies: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    geneSymbol: z.ZodString;
-                    humanEnsemblId: z.ZodNullable<z.ZodString>;
-                    bySpecies: z.ZodArray<z.ZodObject<{
-                        species: z.ZodString;
-                        taxonId: z.ZodNumber;
-                        ensemblId: z.ZodString;
-                        source: z.ZodString;
-                        unit: z.ZodString;
-                        normalization_notes: z.ZodString;
-                        tissues: z.ZodArray<z.ZodObject<{
-                            tissue: z.ZodString;
-                            rank: z.ZodEnum<{
-                                low: "low";
-                                medium: "medium";
-                                high: "high";
-                                absent: "absent";
-                            }>;
-                            expressionScore: z.ZodNullable<z.ZodNumber>;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>>;
-                    notFound: z.ZodArray<z.ZodString>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            clinvar: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    totalFound: z.ZodNumber;
-                    variants: z.ZodArray<z.ZodObject<{
-                        variationId: z.ZodString;
-                        title: z.ZodString;
-                        clinicalSignificance: z.ZodString;
-                        reviewStatus: z.ZodString;
-                        conditions: z.ZodArray<z.ZodString>;
-                        molecularConsequence: z.ZodString;
-                        accession: z.ZodString;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            cbioportal: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    entrezGeneId: z.ZodNullable<z.ZodNumber>;
-                    rows: z.ZodArray<z.ZodObject<{
-                        cancerTypeId: z.ZodString;
-                        cancerTypeName: z.ZodString;
-                        totalSamples: z.ZodNumber;
-                        mutatedSamples: z.ZodNumber;
-                        frequency: z.ZodNumber;
-                        studies: z.ZodArray<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            impc: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    mouseMarkerSymbol: z.ZodNullable<z.ZodString>;
-                    mgiAccessionId: z.ZodNullable<z.ZodString>;
-                    viability: z.ZodNullable<z.ZodEnum<{
-                        lethal_pre_weaning: "lethal_pre_weaning";
-                        subviable: "subviable";
-                        viable: "viable";
-                    }>>;
-                    viabilityCalls: z.ZodArray<z.ZodObject<{
-                        zygosity: z.ZodString;
-                        parameterStableId: z.ZodString;
-                        mpTerm: z.ZodNullable<z.ZodObject<{
-                            id: z.ZodString;
-                            name: z.ZodString;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>>;
-                    mpTerms: z.ZodArray<z.ZodObject<{
-                        id: z.ZodString;
-                        term: z.ZodString;
-                        bestPValue: z.ZodNullable<z.ZodNumber>;
-                    }, z.core.$strip>>;
-                    organSystems: z.ZodArray<z.ZodString>;
-                    sexDimorphic: z.ZodBoolean;
-                    phenotypeCount: z.ZodNumber;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            pubmedIndex: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    totalFound: z.ZodNumber;
-                    topPmids: z.ZodArray<z.ZodString>;
-                    results: z.ZodArray<z.ZodObject<{
-                        pmid: z.ZodString;
-                        title: z.ZodString;
-                        journal: z.ZodString;
-                        year: z.ZodString;
-                        authors: z.ZodString;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            pathways: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    pathways: z.ZodArray<z.ZodObject<{
-                        id: z.ZodString;
-                        name: z.ZodString;
-                        source: z.ZodEnum<{
-                            kegg: "kegg";
-                            reactome: "reactome";
-                        }>;
-                        url: z.ZodOptional<z.ZodString>;
-                        entity_uniprots: z.ZodOptional<z.ZodArray<z.ZodString>>;
-                        metadata: z.ZodOptional<z.ZodObject<{
-                            species_present: z.ZodOptional<z.ZodArray<z.ZodString>>;
-                        }, z.core.$strip>>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            stringPpi: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    partners: z.ZodArray<z.ZodObject<{
-                        proteinA: z.ZodString;
-                        proteinB: z.ZodString;
-                        score: z.ZodNumber;
-                        experimentalScore: z.ZodOptional<z.ZodNumber>;
-                        databaseScore: z.ZodOptional<z.ZodNumber>;
-                        textminingScore: z.ZodOptional<z.ZodNumber>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            familyComplexes: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    primaryTargetGene: z.ZodString;
-                    primaryTargetUniprot: z.ZodNullable<z.ZodString>;
-                    accessoryProteinNames: z.ZodArray<z.ZodString>;
-                    complexes: z.ZodArray<z.ZodObject<{
-                        complexName: z.ZodString;
-                        complexId: z.ZodNullable<z.ZodNumber>;
-                        accessoryNames: z.ZodArray<z.ZodString>;
-                        subunitNames: z.ZodArray<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            monarch: z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    geneCurie: z.ZodString;
-                    phenotypes: z.ZodArray<z.ZodObject<{
-                        hpoId: z.ZodString;
-                        label: z.ZodString;
-                        ancestorIds: z.ZodArray<z.ZodString>;
-                        publications: z.ZodArray<z.ZodString>;
-                        diseaseContext: z.ZodNullable<z.ZodString>;
-                        frequencyPercent: z.ZodNullable<z.ZodNumber>;
-                        primaryKnowledgeSource: z.ZodNullable<z.ZodString>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">;
-            therapeuticPrograms: z.ZodOptional<z.ZodDiscriminatedUnion<[z.ZodObject<{
-                coverage: z.ZodLiteral<"available">;
-                data: z.ZodObject<{
-                    programs: z.ZodArray<z.ZodObject<{
-                        programId: z.ZodString;
-                        name: z.ZodString;
-                        targetSymbol: z.ZodString;
-                        targetUniprot: z.ZodNullable<z.ZodString>;
-                        modality: z.ZodString;
-                        sponsor: z.ZodNullable<z.ZodString>;
-                        mechanism: z.ZodString;
-                        status: z.ZodString;
-                        nctIds: z.ZodArray<z.ZodString>;
-                        pmids: z.ZodArray<z.ZodString>;
-                        evidence: z.ZodArray<z.ZodObject<{
-                            pmid: z.ZodOptional<z.ZodString>;
-                            doi: z.ZodOptional<z.ZodString>;
-                            accession: z.ZodOptional<z.ZodString>;
-                            source: z.ZodString;
-                            predicate: z.ZodOptional<z.ZodString>;
-                            score: z.ZodOptional<z.ZodNumber>;
-                            strength: z.ZodOptional<z.ZodString>;
-                            is_human: z.ZodOptional<z.ZodBoolean>;
-                            is_clinical: z.ZodOptional<z.ZodBoolean>;
-                            excerpt: z.ZodOptional<z.ZodString>;
-                            metadata: z.ZodOptional<z.ZodRecord<z.ZodString, z.ZodUnknown>>;
-                            regulatory_reference: z.ZodOptional<z.ZodObject<{
-                                document: z.ZodString;
-                                section: z.ZodOptional<z.ZodString>;
-                                doc_id: z.ZodOptional<z.ZodString>;
-                                doc_url: z.ZodOptional<z.ZodString>;
-                            }, z.core.$strip>>;
-                        }, z.core.$strip>>;
-                        confidence: z.ZodEnum<{
-                            low: "low";
-                            medium: "medium";
-                            high: "high";
-                        }>;
-                    }, z.core.$strip>>;
-                }, z.core.$strip>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"queried_no_data">;
-                error: z.ZodOptional<z.ZodObject<{
-                    message: z.ZodString;
-                    name: z.ZodOptional<z.ZodString>;
-                    stack: z.ZodOptional<z.ZodString>;
-                }, z.core.$strip>>;
-            }, z.core.$strip>, z.ZodObject<{
-                coverage: z.ZodLiteral<"not_loaded">;
-                reason: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>], "coverage">>;
-        }, z.core.$strip>;
-    }, z.core.$strip>;
-    decisions: z.ZodObject<{
-        modulatorTriage: z.ZodDiscriminatedUnion<[z.ZodObject<{
-            coverage: z.ZodLiteral<"available">;
-            data: z.ZodObject<{
-                shortlist: z.ZodArray<z.ZodObject<{
-                    moleculeChemblId: z.ZodString;
-                    preferredName: z.ZodString;
-                    maxPhase: z.ZodNullable<z.ZodNumber>;
-                    firstApproval: z.ZodNullable<z.ZodNumber>;
-                    rationale: z.ZodString;
-                }, z.core.$strip>>;
-                notes: z.ZodString;
-                dropped_synonyms: z.ZodDefault<z.ZodArray<z.ZodObject<{
-                    chemblId: z.ZodString;
-                    reason: z.ZodEnum<{
-                        same_active_substance: "same_active_substance";
-                        ambiguous_name_synonym: "ambiguous_name_synonym";
-                    }>;
-                    keptId: z.ZodNullable<z.ZodString>;
-                }, z.core.$strip>>>;
-            }, z.core.$strip>;
-        }, z.core.$strip>, z.ZodObject<{
-            coverage: z.ZodLiteral<"queried_no_data">;
-            error: z.ZodOptional<z.ZodObject<{
-                message: z.ZodString;
-                name: z.ZodOptional<z.ZodString>;
-                stack: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>>;
-        }, z.core.$strip>, z.ZodObject<{
-            coverage: z.ZodLiteral<"not_loaded">;
-            reason: z.ZodOptional<z.ZodString>;
-        }, z.core.$strip>], "coverage">;
-        failedTrialClassifier: z.ZodDiscriminatedUnion<[z.ZodObject<{
-            coverage: z.ZodLiteral<"available">;
-            data: z.ZodObject<{
-                classifications: z.ZodDefault<z.ZodArray<z.ZodUnknown>>;
-            }, z.core.$strip>;
-        }, z.core.$strip>, z.ZodObject<{
-            coverage: z.ZodLiteral<"queried_no_data">;
-            error: z.ZodOptional<z.ZodObject<{
-                message: z.ZodString;
-                name: z.ZodOptional<z.ZodString>;
-                stack: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>>;
-        }, z.core.$strip>, z.ZodObject<{
-            coverage: z.ZodLiteral<"not_loaded">;
-            reason: z.ZodOptional<z.ZodString>;
-        }, z.core.$strip>], "coverage">;
-        offTargetCurator: z.ZodDiscriminatedUnion<[z.ZodObject<{
-            coverage: z.ZodLiteral<"available">;
-            data: z.ZodObject<{
-                panel: z.ZodDefault<z.ZodArray<z.ZodUnknown>>;
-                total: z.ZodDefault<z.ZodNumber>;
-                truncated: z.ZodDefault<z.ZodBoolean>;
-                notes: z.ZodDefault<z.ZodString>;
-            }, z.core.$strip>;
-        }, z.core.$strip>, z.ZodObject<{
-            coverage: z.ZodLiteral<"queried_no_data">;
-            error: z.ZodOptional<z.ZodObject<{
-                message: z.ZodString;
-                name: z.ZodOptional<z.ZodString>;
-                stack: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>>;
-        }, z.core.$strip>, z.ZodObject<{
-            coverage: z.ZodLiteral<"not_loaded">;
-            reason: z.ZodOptional<z.ZodString>;
-        }, z.core.$strip>], "coverage">;
-        drugsInClass: z.ZodDiscriminatedUnion<[z.ZodObject<{
-            coverage: z.ZodLiteral<"available">;
-            data: z.ZodObject<{
-                drugs: z.ZodArray<z.ZodObject<{
-                    moleculeChemblId: z.ZodString;
-                    preferredName: z.ZodString;
-                    maxPhase: z.ZodNullable<z.ZodNumber>;
-                    firstApproval: z.ZodNullable<z.ZodNumber>;
-                    moleculeType: z.ZodNullable<z.ZodString>;
-                    sources: z.ZodArray<z.ZodEnum<{
-                        dgidb: "dgidb";
-                        drugbank: "drugbank";
-                        chembl: "chembl";
-                    }>>;
-                }, z.core.$strip>>;
-                total: z.ZodNumber;
-                truncated: z.ZodBoolean;
-            }, z.core.$strip>;
-        }, z.core.$strip>, z.ZodObject<{
-            coverage: z.ZodLiteral<"queried_no_data">;
-            error: z.ZodOptional<z.ZodObject<{
-                message: z.ZodString;
-                name: z.ZodOptional<z.ZodString>;
-                stack: z.ZodOptional<z.ZodString>;
-            }, z.core.$strip>>;
-        }, z.core.$strip>, z.ZodObject<{
-            coverage: z.ZodLiteral<"not_loaded">;
-            reason: z.ZodOptional<z.ZodString>;
-        }, z.core.$strip>], "coverage">;
-    }, z.core.$strip>;
-}, z.core.$strip>;
-export type Phase2Bundle = z.infer<typeof Phase2BundleSchema>;