ruby-ensembl-api 0.9.6 → 1.0

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Files changed (62) hide show
  1. data/TUTORIAL.rdoc +1 -1
  2. data/bin/variation_effect_predictor +106 -0
  3. data/lib/ensembl.rb +2 -2
  4. data/lib/ensembl/core/activerecord.rb +119 -225
  5. data/lib/ensembl/core/collection.rb +14 -10
  6. data/lib/ensembl/core/project.rb +6 -8
  7. data/lib/ensembl/core/slice.rb +87 -123
  8. data/lib/ensembl/core/transcript.rb +49 -65
  9. data/lib/ensembl/core/transform.rb +6 -8
  10. data/lib/ensembl/db_connection.rb +56 -72
  11. data/lib/ensembl/variation/activerecord.rb +138 -8
  12. data/lib/ensembl/variation/variation.rb +284 -46
  13. data/samples/ensembl_genomes_example.rb +60 -0
  14. data/samples/examples_perl_tutorial.rb +125 -0
  15. data/samples/small_example_ruby_api.rb +34 -0
  16. data/samples/variation_example.rb +67 -0
  17. data/test/unit/{release_56 → release_60}/core/test_gene.rb +6 -6
  18. data/test/unit/release_60/core/test_project_human.rb +38 -0
  19. data/test/unit/{release_56 → release_60}/core/test_slice.rb +1 -8
  20. data/test/unit/release_60/core/test_transcript.rb +126 -0
  21. data/test/unit/{release_53 → release_60}/core/test_transform.rb +21 -21
  22. data/test/unit/release_60/variation/test_activerecord.rb +213 -0
  23. data/test/unit/release_60/variation/test_consequence.rb +158 -0
  24. data/test/unit/{release_56 → release_60}/variation/test_variation.rb +18 -17
  25. data/test/unit/test_connection.rb +2 -2
  26. data/test/unit/test_releases.rb +8 -8
  27. metadata +27 -43
  28. data/test/unit/data/seq_c6qbl.fa +0 -10
  29. data/test/unit/data/seq_cso19_coding.fa +0 -16
  30. data/test/unit/data/seq_cso19_transcript.fa +0 -28
  31. data/test/unit/data/seq_drd3_gene.fa +0 -838
  32. data/test/unit/data/seq_drd3_transcript.fa +0 -22
  33. data/test/unit/data/seq_drd4_transcript.fa +0 -24
  34. data/test/unit/data/seq_forward_composite.fa +0 -1669
  35. data/test/unit/data/seq_par_boundary.fa +0 -169
  36. data/test/unit/data/seq_rnd3_transcript.fa +0 -47
  37. data/test/unit/data/seq_ub2r1_coding.fa +0 -13
  38. data/test/unit/data/seq_ub2r1_gene.fa +0 -174
  39. data/test/unit/data/seq_ub2r1_transcript.fa +0 -26
  40. data/test/unit/data/seq_y.fa +0 -2
  41. data/test/unit/ensembl_genomes/test_collection.rb +0 -51
  42. data/test/unit/ensembl_genomes/test_gene.rb +0 -52
  43. data/test/unit/ensembl_genomes/test_slice.rb +0 -71
  44. data/test/unit/ensembl_genomes/test_variation.rb +0 -17
  45. data/test/unit/release_50/core/test_project.rb +0 -215
  46. data/test/unit/release_50/core/test_project_human.rb +0 -58
  47. data/test/unit/release_50/core/test_relationships.rb +0 -66
  48. data/test/unit/release_50/core/test_sequence.rb +0 -175
  49. data/test/unit/release_50/core/test_slice.rb +0 -121
  50. data/test/unit/release_50/core/test_transcript.rb +0 -108
  51. data/test/unit/release_50/core/test_transform.rb +0 -223
  52. data/test/unit/release_50/variation/test_activerecord.rb +0 -143
  53. data/test/unit/release_50/variation/test_variation.rb +0 -84
  54. data/test/unit/release_53/core/test_gene.rb +0 -66
  55. data/test/unit/release_53/core/test_project.rb +0 -96
  56. data/test/unit/release_53/core/test_project_human.rb +0 -65
  57. data/test/unit/release_53/core/test_slice.rb +0 -47
  58. data/test/unit/release_53/variation/test_activerecord.rb +0 -145
  59. data/test/unit/release_53/variation/test_variation.rb +0 -71
  60. data/test/unit/release_56/core/test_project.rb +0 -96
  61. data/test/unit/release_56/core/test_transform.rb +0 -63
  62. data/test/unit/release_56/variation/test_activerecord.rb +0 -142
@@ -1,175 +0,0 @@
1
- #
2
- # = test/unit/test_seq.rb - Unit test for Ensembl::Core
3
- #
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- # Copyright:: Copyright (C) 2007
5
- # Jan Aerts <http://jandot.myopenid.com>
6
- # License:: Ruby's
7
- #
8
- # $Id:
9
- require 'pathname'
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- libpath = Pathname.new(File.join(File.dirname(__FILE__), ['..'] * 4, 'lib')).cleanpath.to_s
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- $:.unshift(libpath) unless $:.include?(libpath)
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-
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- require 'test/unit'
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- require 'yaml'
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- require 'lib/ensembl'
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-
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- include Ensembl::Core
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-
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- DBConnection.connect('homo_sapiens', 50)
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-
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- #class SequenceForSlice < Test::Unit::TestCase
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- # def test_forward_strand_seqlevel
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- # slice = Slice.new(SeqRegion.find(170931),5,15)
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- # seq = 'gcagtggtgtg'
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- # assert_equal(seq, slice.seq)
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- # end
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- #
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- # def test_reverse_strand_seqlevel
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- # slice = Slice.new(SeqRegion.find(170931),5,15, -1)
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- # seq = 'cacaccactgc'
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- # assert_equal(seq, slice.seq)
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- # end
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- #
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- # def test_forward_strand_not_seqlevel_single_target
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- # slice = Slice.new(SeqRegion.find(226044),69437100,69437110)
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- # seq = 'gtctatttaca'
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- # assert_equal(seq, slice.seq)
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- # end
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- #
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- # def test_reverse_strand_not_seqlevel_single_target
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- # slice = Slice.new(SeqRegion.find(226044),69437100,69437110,-1)
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- # seq = 'tgtaaatagac'
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- # assert_equal(seq, slice.seq)
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- # end
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- #
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- # def test_forward_strand_not_seqlevel_composite_target
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- # seq = ''
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- # File.open('../../data/seq_forward_composite.fa').reject{|l| l=~/^>/}.each do |line|
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- # line.chomp!
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- # seq += line
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- # end
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- # seq.downcase!
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- # slice = Slice.new(SeqRegion.find(226044),69387650,69487649)
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- # assert_equal(seq, slice.seq)
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- # end
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- #
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- # def test_reverse_strand_not_seqlevel_composite_target
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- # slice = Slice.new(SeqRegion.find(226044),69437061,69437160,-1)
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- # assert_equal('nnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnnatgtaaatagacaactaacaagatagctgagattgtttccttatccagaca', slice.seq)
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- # end
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- #
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- #end
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- #
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- #class SequenceForUnsplicedFeature < Test::Unit::TestCase
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- # def test_forward_strand_seqlevel
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- # marker_feature = MarkerFeature.find(1323757)
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- # marker_seq = 'ggcttacttggaaaggtctcttccaacccaatattattcaaatactttcaattttcttctaatgtttttagtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtggttttgttttatttcttttaattctctgatacatttagaatttcttttattattttattttattttattatttatttatttatttttgagacagagttttgctc'
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- # assert_equal(marker_seq, marker_feature.seq)
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- # end
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- #
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- # def test_reverse_strand_seqlevel
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- # gene = Gene.find_by_name('ANKRD56')
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- #
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- # ankrd56_seq = 'atggcccgagagctgagccaggaggcactactggactttctgtgccaggctgggggccgcgtgaccaacgctgccttgctgagccacttcaagagctttctccgagaccccgacgcgtcccccagccagcaccagcaccgccgcgagctcttcaagggcttcgtcaactcggtcgccgcagtgcgccaggaccccgacggcaccaagtacgtggtgctcaagaggagatacagggaccttttgggggaggaggggctgcagcgaccccgcgagccgcccgcggccgcccccagtgcagggggagctgcgccctgctccccgcgaggcgcgcgccggggggagccgccccagcagcagcccaggcggcggcggcgcgagaaggagccggaggaggagccagcaggtgcagcagccagagccgccgacgcagcttgcaatggactcccgggcagcgactcccgtagggcgcccgggaagggcggcggatcgaagggcagtcccggacagaggccgccggtgcccgcagctgcagcggcaggggcccaggcgagagcgagctgcgcggcggcgaagacgcagggccgctgctgctgggaatgcctccagaacaacctggctgtactgccgggagagctcggcgcactcccgcactcggccaccgcggaggagaagccggcacgggctctgcctgcccaggatgaccgcggggcttccagggagcgggaagaaggcgcgctagctgagccggcgcctgtgcctgcagtggctcactcgcctcccgccaccgtcgaggctgcgacaagcagggcttccccgcctgctctcctgcccggccccgctccccgcggagaccggccggagctgctgacccccagctccctgcattattcgaccctgcagcagcagcagcagcgcactcgagagtgggtggccaggcacccgcaggtgcccgaggcccgtgatcagggccctatccgcgcctggtcggtgctgccagacaacttcctccagctgcccttggaacccggctccacggagcctaattcagagccgccagacccctgtctttcctcgcactctctctttcctgttgttccggatgagtcctgggaatcctgggcggggaacccttcattgactgtctttcgcagcattcgttgtcagctgtccctccaagatctggatgactttgtggaccaggagagtgatggcagtgaggagagcagcagtgggcccaaagactccccgggggcttctgaagaggggctgcaggttgtcttgggaaccccagatagggggaagctcaggaatccagctgggggcctttctgtatctcggaaggagggcagccccagccggagccctcagggtctcagaaacagaggggatggtcacatctctcagcaggtccctgcaggggctaatggccttgcaggccaccccctgaagcctttgccttggccagttcctaagttaaggaggtccctcaggaggagctctctggcagggagagccaaattgtcctcctctgatgaggagtacctcgatgagggcttgctgaaaagaagtcggcgcccacctcgatccaggaagccctccaaggcaggaacggcacccagcccaagggttgatgcaggtttatcactaaaacttgcagaggttaaggctgttgtggccgagcggggttggcgacacagcctgtgggtccccagtggggaggggtctgcagccttggccccccacagaacttctgagcacaaatcatccctggttccactagatgccagggagcatgagtggattgtgaagcttgccagtggctcctggattcaggtgtggactttgttctgggaggaccctcaactggccttgcacaaagactttttgactgggtacactgcgttgcactggatagccaaacatggtgacctcagggcccttcaggacttggtgtctggagcaaagaaggcagggattgtccttgatgtaaacgtgaggtccagttgtggatataccccgctgcaccttgcagccattcacggccaccagggggtcatcaaattgctagtgcaaaggttggcttctcgggtaaatgtcagggacagcagtgggaagaagccatggcagtatctaaccagtaatacctctggggaaatatggcagctgttgggagctcctcggggcaagcccattttccctgtctatcccttagttggaagttcttcccctaccagaaaggccaagagcaaggaaatatctagaagtgtcacccgaaaaacttccttcgctgcactactcaaaagtcagcacaacaagtggaaactggccaaccagtatgagaaattccacagtccaagggaaagagaagagtatagtgactga'
75
- # assert_equal(ankrd56_seq, gene.seq)
76
- # end
77
- #
78
- # def test_reverse_strand_not_seqlevel
79
- # gene = Gene.find_by_name('DRD3')
80
- # drd3_gene_seq = ''
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- # File.open('../../data/seq_drd3_gene.fa').reject{|l| l=~/^>/}.each do |line|
82
- # line.chomp!
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- # drd3_gene_seq += line
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- # end
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- # drd3_gene_seq.downcase!
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- # assert_equal(drd3_gene_seq, gene.seq)
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- #
88
- # end
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- #
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- # def test_exon
91
- # exon = Exon.find(719588)
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- # assert_equal('atggcatctctgagccagctgagtggccacctgaactacacctgtggggcagagaactccacaggtgccagccaggcccgcccacatgcctactatgccctctcctactgcgcgctcatcctggccatcgtcttcggcaatggcctggtgtgcatggctgtgctgaaggagcgggccctgcagactaccaccaactacttagtagtgagcctggctgtggcagacttgctggtggccaccttggtgatgccctgggtggtatacctggag', exon.seq)
93
- # end
94
- #
95
- #end
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-
97
- class SequenceForSlicedFeature < Test::Unit::TestCase
98
- def test_transcript_foward
99
- transcript = Transcript.find(73491) # UB2R1 = CDC34
100
- ub2r1_transcript_seq = ''
101
- File.open('test/unit/data/seq_ub2r1_transcript.fa').reject{|l| l=~/^>/}.each do |line|
102
- line.chomp!
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- ub2r1_transcript_seq += line
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- end
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- ub2r1_transcript_seq.downcase!
106
- assert_equal(ub2r1_transcript_seq, transcript.seq)
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-
108
- end
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-
110
- def test_transcript_reverse
111
- transcript = Transcript.find(107548)
112
- rnd3_transcript_seq = ''
113
- File.open('test/unit/data/seq_rnd3_transcript.fa').reject{|l| l=~/^>/}.each do |line|
114
- line.chomp!
115
- rnd3_transcript_seq += line
116
- end
117
- rnd3_transcript_seq.downcase!
118
- assert_equal(rnd3_transcript_seq, transcript.seq)
119
- end
120
-
121
- end
122
-
123
- class SequenceForCDS < Test::Unit::TestCase
124
- def setup
125
- # Transcript tr_fw is ENST00000215574
126
- @tr_fw = Transcript.find(73491)
127
- # Transcript tr_rev is ENST00000315489
128
- @tr_rev = Transcript.find(73411)
129
- end
130
-
131
- def test_cds_fw
132
- ub2r1_coding_seq = ''
133
- File.open('test/unit/data/seq_ub2r1_coding.fa').reject{|l| l=~/^>/}.each do |line|
134
- line.chomp!
135
- ub2r1_coding_seq += line
136
- end
137
- ub2r1_coding_seq.downcase!
138
- assert_equal(ub2r1_coding_seq, @tr_fw.cds_seq)
139
- end
140
-
141
- def test_cds_rev
142
- cso19_coding_seq = ''
143
- File.open('test/unit/data/seq_cso19_coding.fa').reject{|l| l=~/^>/}.each do |line|
144
- line.chomp!
145
- cso19_coding_seq += line
146
- end
147
- cso19_coding_seq.downcase!
148
- assert_equal(cso19_coding_seq, @tr_rev.cds_seq)
149
- end
150
-
151
- def test_five_prime_utr_fw
152
- assert_equal('GGCAAGCGCCGGTGGGGCGGCGGCGCCAGAGCTGCTGGAGCGCTCGGGGTCCCCGGGCGGCGGCGGCGGCGCAGAGGAGGAGGCAGGCGGCGGCCCCGGTGGCTCCCCCCCGGACGGTGCGCGGCCCGGCCCGTCTCGCGAACTCGCGGTGGTCGCGCGGCCCCGCGCTGCTCCGACCCCGGGCCCCTCCGCCGCCGCC'.downcase, @tr_fw.five_prime_utr_seq)
153
- end
154
-
155
- def test_five_primer_utr_rev
156
- assert_equal('ACTCGATCCCGGCCCCACTTCCAGGCCAGTGTCCGGCCGACCAGCCTGCCTTGGGCCAGGGCCCCACGACTCCCTGCTGCGGGACAAGAGGCCGTCTGTGCGGCTGTGGTCGTGGGAGGGTGTGGTGAGGCCGTGAAGGTGGGGACGGTGCCTGGGCCTGTGGCCGCCAGAGCTGCTGCGGCTCAGAAGGTAGCACCAGGCCCCGTGGGTGCTGTGGGGGCCATCGCCTGCCCACC'.downcase, @tr_rev.five_prime_utr_seq)
157
- end
158
-
159
- def test_three_prime_utr_fw
160
- assert_equal('CACCACCAGAATAAACTTGCCGAGTTTACCTCACTAGGGCCGGACCCGTGGCTCCTTAGACGACAGACTACCTCACGGAGGTTTTGTGCTGGTCCCCGTCTCCTCTGGTTGTTTCGTTTTGGCTTTTTCTCCCTCCCCATGTCTGTTCTGGGTTTTCACGTGCTTCAGAGAAGAGGGGCTGCCCCACCGCCACTCACGTCACTCGGGGCTCGGTGGACGGGCCCAGGGTGGGAGCGGCCGGCCCACCTGTCCCCTCGGGAGGGGAGCTGAGCCCGACTTCTACCGGGGTCCCCCAGCTTCCGGACTGGCCGCACCCCGGAGGAGCCACGGGGGCGCTGCTGGGAACGTGGGCGGGGGGCCGTTTCCTGACACTACCAGCCTGGGAGGCCCAGGTGTAGCGGTCCGAGGGGCCCGGTCCTGCCTGTCAGCTCCAGGTCCTGGAGCCACGTCCAGCACAGAGTGGACGGATTCACCGTGGCCGACTCTTTTCCCTGCTTTGGTTTGTTTGAAATCTAAATAAAACTACTTTATG'.downcase, @tr_fw.three_prime_utr_seq)
161
- end
162
-
163
- def test_three_prime_utr_rev
164
- assert_equal('GCCAGGCCTGTTTCCCACACAGTGAACGGGGGGCTGGCGGGCCTCTCCTGGGGCCTGGCTTTGGCTGGAGGGGCTAGAAGGCGAGAGGGGCTGGGAAAGGAGTCTTCCCTCCCCTTTCCTGAACTGTCCAGGTCCTTCTAGGACACCTGATCCTTCCAGTCCCTGGGGGCTGTGACCCATGGCCCTGTGCAGGGTGCAGGGTGAGTCTCCTTCCAGTGCCCCAGTTTCTTCCAGGTCACGCCAGGCCAGGCCAGGCCAGGTGGGGAAAGGGACACCTTCCGGCCCTCCCCAGTAGCTGGCTGGAGATGGAGCTTCCTGTGTCCCAGAACTCGGCGTCCAGCTCCACTAGGGCCTGGATCCCCATCACAGCTTGGGTTAGCCCCGGTCCCAGCCCAAACTCAGGCTGGAGGCAGCCCCGAGGCCTGTGCCTTTCCCACTCCACCTTCTACAGTTGCTTAGCCAATAAACCTTTCCTGGGCTGGAG'.downcase, @tr_rev.three_prime_utr_seq)
165
- end
166
-
167
- def test_protein_fw
168
- assert_equal('MARPLVPSSQKALLLELKGLQEEPVEGFRVTLVDEGDLYNWEVAIFGPPNTYYEGGYFKARLKFPIDYPYSPPAFRFLTKMWHPNIYETGDVCISILHPPVDDPQSGELPSERWNPTQNVRTILLSVISLLNEPNTFSPANVDASVMYRKWKESKGKDREYTDIIRKQVLGTKVDAERDGVKVPTTLAEYCVKTKAPAPDEGSDLFYDDYYEDGEVEEEADSCFGDDEDDSGTEES*', @tr_fw.protein_seq)
169
- end
170
-
171
- def test_protein_rev
172
- assert_equal('MGTLSCDSTPRLATAPLGRRVTEGQIPETGLRKSCGTATLENGSGPGLYVLPSTVGFINHDCTRVASPAYSLVRRPSEAPPQDTSPGPIYFLDPKVTRFGRSCTPAYSMQGRAKSRGPEVTPGPGAYSPEKVPPVRHRTPPAFTLGCRLPLKPLDTSAPAPNAYTMPPLWGSQIFTKPSSPSYTVVGRTPPARPPQDPAEIPGPGQYDSPDANTYRQRLPAFTMLGRPRAPRPLEETPGPGAHCPEQVTVNKARAPAFSMGIRHSKRASTMAATTPSRPAGHRLPGRCC*', @tr_rev.protein_seq)
173
- end
174
- end
175
-
@@ -1,121 +0,0 @@
1
- #
2
- # = test/unit/test_project.rb - Unit test for Ensembl::Core
3
- #
4
- # Copyright:: Copyright (C) 2007
5
- # Jan Aerts <http://jandot.myopenid.com>
6
- # License:: Ruby's
7
- #
8
- # $Id:
9
- require 'pathname'
10
- libpath = Pathname.new(File.join(File.dirname(__FILE__), ['..'] * 4, 'lib')).cleanpath.to_s
11
- $:.unshift(libpath) unless $:.include?(libpath)
12
-
13
- require 'test/unit'
14
- require 'lib/ensembl'
15
-
16
- include Ensembl::Core
17
- DBConnection.connect('bos_taurus', 50)
18
-
19
- class GetFeatures < Test::Unit::TestCase
20
- # Chr4.003.122 has no simple features in itself, but the corresponding region
21
- # covered by the chromosome has 37. In addition, contigs within the scaffold
22
- # have 85. Total should therefore be 122.
23
- def test_simple_features
24
- contig = SeqRegion.find_by_name('AAFC03055312')
25
- assert_equal(19, contig.simple_features.length)
26
- assert_equal(19, contig.slice.simple_features.length)
27
- slice = Slice.fetch_by_region('contig','AAFC03055312')
28
- assert_equal(19, slice.simple_features.length)
29
- end
30
- end
31
-
32
- class SliceMethodMissing < Test::Unit::TestCase
33
- def setup
34
- @slice = Slice.fetch_by_region('chromosome','4',10000,10000000)
35
- end
36
-
37
- # There is not NotExistingTable class
38
- def test_non_existing_tables
39
- assert_raise(NoMethodError) { @slice.not_existing_tables }
40
- end
41
-
42
- # A slice can get its exons
43
- def test_exons
44
- assert_equal(291, @slice.exons.length)
45
- assert_equal(Exon, @slice.exons[0].class)
46
- end
47
-
48
- # A slice can _not_ get its markers; it has marker_features instead.
49
- def test_markers
50
- assert_raise(NoMethodError) { @slice.markers }
51
- end
52
-
53
- def test_transcripts
54
- assert_equal(36, @slice.transcripts.length)
55
- end
56
- end
57
-
58
- class GetOverlappingObjects < Test::Unit::TestCase
59
- def setup
60
- @small_slice = Slice.fetch_by_region('chromosome','Un.004.10515',850,900)
61
- @genes_inclusive = @small_slice.genes(true)
62
- @genes_exclusive = @small_slice.genes
63
-
64
- @large_slice = Slice.fetch_by_region('contig','AAFC03055312',1,18210)
65
- @repeats_inclusive = @large_slice.repeat_features(true).select{|r| r.analysis_id == 6}
66
- end
67
-
68
- def test_get_gene
69
- assert_equal(1, @genes_inclusive.length)
70
- assert_equal('ENSBTAG00000039669', @genes_inclusive[0].stable_id)
71
- assert_equal(0, @genes_exclusive.length)
72
- end
73
-
74
- def test_get_repeat_features
75
- assert_equal(2, @repeats_inclusive.length)
76
- end
77
- end
78
-
79
- class ExcisingSlice < Test::Unit::TestCase
80
- def setup
81
- @original_slice = Slice.fetch_by_region('chromosome','1',1,1000)
82
- end
83
-
84
- def test_excise_one_range
85
- output = @original_slice.excise([20..50])
86
- assert_equal(2, output.length)
87
- assert_equal('chromosome:Btau_4.0:1:1:19:1', output[0].to_s)
88
- assert_equal('chromosome:Btau_4.0:1:51:1000:1', output[1].to_s)
89
- end
90
-
91
- def test_excise_two_nonoverlapping_ranges
92
- output = @original_slice.excise([20..50,100..200])
93
- assert_equal(3, output.length)
94
- assert_equal('chromosome:Btau_4.0:1:1:19:1', output[0].to_s)
95
- assert_equal('chromosome:Btau_4.0:1:51:99:1', output[1].to_s)
96
- assert_equal('chromosome:Btau_4.0:1:201:1000:1', output[2].to_s)
97
- end
98
-
99
- def test_excise_two_overlapping_ranges
100
- output = @original_slice.excise([20..150,100..200])
101
- assert_equal(2, output.length)
102
- assert_equal('chromosome:Btau_4.0:1:1:19:1', output[0].to_s)
103
- assert_equal('chromosome:Btau_4.0:1:201:1000:1', output[1].to_s)
104
- end
105
-
106
- def test_excise_two_adjacent_ranges
107
- output = @original_slice.excise([20..99,100..200])
108
- assert_equal(2, output.length)
109
- assert_equal('chromosome:Btau_4.0:1:1:19:1', output[0].to_s)
110
- assert_equal('chromosome:Btau_4.0:1:201:1000:1', output[1].to_s)
111
- end
112
-
113
- def test_excise_internal_ranges
114
- output = @original_slice.excise([20..300,100..200])
115
- assert_equal(2, output.length)
116
- assert_equal('chromosome:Btau_4.0:1:1:19:1', output[0].to_s)
117
- assert_equal('chromosome:Btau_4.0:1:201:1000:1', output[1].to_s)
118
- end
119
-
120
-
121
- end
@@ -1,108 +0,0 @@
1
- #
2
- # = test/unit/test_transcript.rb - Unit test for Ensembl::Core
3
- #
4
- # Copyright:: Copyright (C) 2007
5
- # Jan Aerts <http://jandot.myopenid.com>
6
- # License:: Ruby's
7
- #
8
- # $Id:
9
- require 'pathname'
10
- libpath = Pathname.new(File.join(File.dirname(__FILE__), ['..'] * 4, 'lib')).cleanpath.to_s
11
- $:.unshift(libpath) unless $:.include?(libpath)
12
-
13
- require 'test/unit'
14
-
15
- require 'lib/ensembl'
16
-
17
- include Ensembl::Core
18
-
19
- DBConnection.connect('homo_sapiens', 50)
20
-
21
- class CodingPositions < Test::Unit::TestCase
22
- def setup
23
- # Transcript tr_fw is ENST00000215574
24
- @tr_fw = Transcript.find(73491)
25
- # Transcript tr_rev is ENST00000358041
26
- @tr_rev = Transcript.find(73774)
27
- end
28
-
29
- def test_transcript_coords
30
- assert_equal(482733, @tr_fw.seq_region_start)
31
- assert_equal(493084, @tr_fw.seq_region_end)
32
- assert_equal(595371, @tr_rev.seq_region_start)
33
- assert_equal(598309, @tr_rev.seq_region_end)
34
- end
35
-
36
- def test_coding_regions_genomic_coords_of_fw
37
- assert_equal(482932, @tr_fw.coding_region_genomic_start)
38
- assert_equal(492552, @tr_fw.coding_region_genomic_end)
39
- end
40
-
41
- def test_coding_regions_genomic_coords_of_rev
42
- assert_equal(597652, @tr_rev.coding_region_genomic_start)
43
- assert_equal(598047, @tr_rev.coding_region_genomic_end)
44
- end
45
-
46
- def test_coding_regions_cdna_coords_of_fw
47
- assert_equal(200, @tr_fw.coding_region_cdna_start)
48
- assert_equal(910, @tr_fw.coding_region_cdna_end)
49
- end
50
-
51
- def test_coding_regions_cdna_coords_of_rev
52
- assert_equal(263, @tr_rev.coding_region_cdna_start)
53
- assert_equal(658, @tr_rev.coding_region_cdna_end)
54
- end
55
-
56
- end
57
-
58
- class GenomicVsCDna < Test::Unit::TestCase
59
- def setup
60
- # Transcript tr_fw is ENST00000215574
61
- @tr_fw = Transcript.find(73491)
62
- # Transcript tr_rev is ENST00000315489
63
- @tr_rev = Transcript.find(73411)
64
- end
65
-
66
- def test_identify_exon
67
- assert_equal(Exon.find(374767), @tr_fw.exon_for_cdna_position(601))
68
- assert_equal(Exon.find(374767), @tr_fw.exon_for_genomic_position(488053))
69
- assert_equal(Exon.find(374458), @tr_rev.exon_for_cdna_position(541))
70
- assert_equal(Exon.find(374458), @tr_rev.exon_for_genomic_position(418719))
71
- end
72
-
73
- def test_cdna2genomic
74
- assert_equal(488053, @tr_fw.cdna2genomic(601))
75
- assert_equal(418719, @tr_rev.cdna2genomic(541))
76
- end
77
-
78
- def test_cds2genomic
79
- assert_equal(488053, @tr_fw.cds2genomic(401))
80
- assert_equal(418719, @tr_rev.cds2genomic(304))
81
- end
82
-
83
- def test_genomic2cdna
84
- assert_equal(601, @tr_fw.genomic2cdna(488053))
85
- assert_equal(541, @tr_rev.genomic2cdna(418719))
86
- end
87
-
88
- def test_genomic2cds
89
- assert_equal(401, @tr_fw.genomic2cds(488053))
90
- assert_equal(304, @tr_rev.genomic2cds(418719))
91
- end
92
- end
93
-
94
- class TestIntron < Test::Unit::TestCase
95
- def setup
96
- @transcript = Transcript.find(58973)
97
- @introns = @transcript.introns
98
- end
99
-
100
- def test_get_introns
101
- assert_equal(2, @introns.length)
102
- end
103
-
104
- def test_intron_slices
105
- assert_equal('chromosome:NCBI36:8:159418:172128:-1', @introns[0].slice.to_s)
106
- end
107
- end
108
-
@@ -1,223 +0,0 @@
1
- #
2
- # = test/unit/test_transform.rb - Unit test for Ensembl::Core
3
- #
4
- # Copyright:: Copyright (C) 2007
5
- # Jan Aerts <http://jandot.myopenid.com>
6
- # License:: Ruby's
7
- #
8
- # $Id:
9
- require 'pathname'
10
- libpath = Pathname.new(File.join(File.dirname(__FILE__), ['..'] * 4, 'lib')).cleanpath.to_s
11
- $:.unshift(libpath) unless $:.include?(libpath)
12
-
13
- require 'test/unit'
14
-
15
- require 'lib/ensembl'
16
-
17
- include Ensembl::Core
18
- DBConnection.connect('bos_taurus', 50)
19
-
20
- # For all tests, the source (i.e. the seq_region that the feature is annotated
21
- # on initially) remains forward.
22
- #
23
- # Same coordinate system: test names refer to direction of gene vs chromosome
24
- class TransformOntoSameCoordinateSystem < Test::Unit::TestCase
25
- # |-------|========>-------------------------> chromosome
26
- # ^ ^
27
- # | |
28
- # |-------|========>-------------------------> chromosome
29
- # This should return itself.
30
- def test_fw
31
- source_gene = Gene.find(6043)
32
- target_gene = source_gene.transform('chromosome')
33
-
34
- assert_equal('4', source_gene.seq_region.name)
35
- assert_equal(4595538, source_gene.seq_region_start)
36
- assert_equal(4827723, source_gene.seq_region_end)
37
- assert_equal(1, source_gene.seq_region_strand)
38
- assert_equal('4', target_gene.seq_region.name)
39
- assert_equal(4595538, target_gene.seq_region_start)
40
- assert_equal(4827723, target_gene.seq_region_end)
41
- assert_equal(1, target_gene.seq_region_strand)
42
- end
43
-
44
- # |-------<========|-------------------------> chromosome
45
- # ^ ^
46
- # | |
47
- # |-------<========|-------------------------> chromosome
48
- # This should return itself.
49
- def test_rev
50
- source_gene = Gene.find(6053)
51
- target_gene = source_gene.transform('chromosome')
52
-
53
- assert_equal('4', source_gene.seq_region.name)
54
- assert_equal(5199677, source_gene.seq_region_start)
55
- assert_equal(5201728, source_gene.seq_region_end)
56
- assert_equal(-1, source_gene.seq_region_strand)
57
- assert_equal('4', target_gene.seq_region.name)
58
- assert_equal(5199677, target_gene.seq_region_start)
59
- assert_equal(5201728, target_gene.seq_region_end)
60
- assert_equal(-1, target_gene.seq_region_strand)
61
- end
62
- end
63
-
64
- ## Test names refer to:
65
- ## (1) direction of gene vs chromosome
66
- ## (2) direction of component (scaffold) vs assembly (chromosome)
67
- #class TransformFromComponentToAssembly < Test::Unit::TestCase
68
- # def test_fw_fw
69
- # assert true
70
- # end
71
- #
72
- # def test_fw_rev
73
- # assert true
74
- # end
75
- #
76
- # def test_rev_fw
77
- # assert true
78
- # end
79
- #
80
- # def test_rev_rev
81
- # assert true
82
- # end
83
- #end
84
- #
85
- ## Test names refer to:
86
- ## (1) direction of gene vs chromosome
87
- ## (2) direction of component (scaffold) vs assembly (chromosome)
88
- ## We have to test for features that are covered by a scaffold, and those
89
- ## overlapping more than 1 scaffold.
90
- #class TransformFromAssemblyToComponent < Test::Unit::TestCase
91
- # # |-----------------> scaffold
92
- # # ^ ^
93
- # # | |
94
- # # |---------|=====>-----------------------------> chromosome
95
- # def test_fw_fw_full_overlap
96
- # source_gene = Gene.find(2995)
97
- # target_gene = source_gene.transform('scaffold')
98
- #
99
- # assert_equal('4', source_gene.seq_region.name)
100
- # assert_equal(10333321, source_gene.seq_region_start)
101
- # assert_equal(10510842, source_gene.seq_region_end)
102
- # assert_equal(1, source_gene.seq_region_strand)
103
- # assert_equal('Chr4.003.12', target_gene.seq_region.name)
104
- # assert_equal(43842, target_gene.seq_region_start)
105
- # assert_equal(221363, target_gene.seq_region_end)
106
- # assert_equal(1, target_gene.seq_region_strand)
107
- # end
108
- #
109
- # # |-----------------> scaffold
110
- # # |
111
- # # |
112
- # # |---|===>-------------------------------> chromosome
113
- # def test_fw_fw_partial_overlap
114
- # source_feature = PredictionTranscript.find(52425)
115
- # target_feature = source_feature.transform('scaffold')
116
- #
117
- # assert_equal('4', source_feature.seq_region.name)
118
- # assert_equal(1443280, source_feature.seq_region_start)
119
- # assert_equal(1482777, source_feature.seq_region_end)
120
- # assert_equal(1, source_feature.seq_region_strand)
121
- # assert_equal(nil, target_feature)
122
- # end
123
- #
124
- # # <-----------------| scaffold
125
- # # ^ ^
126
- # # | |
127
- # # |----------|=====>-----------------------------> chromosome
128
- # def test_fw_rev_full_overlap
129
- # source_gene = Gene.find(2708)
130
- # target_gene = source_gene.transform('scaffold')
131
- #
132
- # assert_equal('4', source_gene.seq_region.name)
133
- # assert_equal(8312492, source_gene.seq_region_start)
134
- # assert_equal(8312812, source_gene.seq_region_end)
135
- # assert_equal(1, source_gene.seq_region_strand)
136
- # assert_equal('Chr4.003.10', target_gene.seq_region.name)
137
- # assert_equal(1774466, target_gene.seq_region_start)
138
- # assert_equal(1774786, target_gene.seq_region_end)
139
- # assert_equal(-1, target_gene.seq_region_strand)
140
- # end
141
- #
142
- # # <-----------------| scaffold
143
- # # |
144
- # # |
145
- # # |---------------------|===>------------------> chromosome
146
- # def test_fw_rev_partial_overlap
147
- # source_feature = PredictionTranscript.find(23305)
148
- # target_feature = source_feature.transform('scaffold')
149
- #
150
- # assert_equal('4', source_feature.seq_region.name)
151
- # assert_equal(10008188, source_feature.seq_region_start)
152
- # assert_equal(10156104, source_feature.seq_region_end)
153
- # assert_equal(1, source_feature.seq_region_strand)
154
- # assert_equal(nil, target_feature)
155
- # end
156
- #
157
- # # |-----------------> scaffold
158
- # # | ^ ^
159
- # # | | |
160
- # # |---<===|--<=====|-----------------------------> chromosome
161
- # def test_rev_fw_full_overlap
162
- # source_gene = Gene.find(3124)
163
- # target_gene = source_gene.transform('scaffold')
164
- #
165
- # assert_equal('4', source_gene.seq_region.name)
166
- # assert_equal(10353230, source_gene.seq_region_start)
167
- # assert_equal(10371155, source_gene.seq_region_end)
168
- # assert_equal(-1, source_gene.seq_region_strand)
169
- # assert_equal('Chr4.003.12', target_gene.seq_region.name)
170
- # assert_equal(63751, target_gene.seq_region_start)
171
- # assert_equal(81676, target_gene.seq_region_end)
172
- # assert_equal(-1, target_gene.seq_region_strand)
173
- # end
174
- #
175
- # # |-----------------> scaffold
176
- # # |
177
- # # |
178
- # # |---------------------<===|------------------> chromosome
179
- # def test_rev_fw_partial_overlap
180
- # source_feature = PredictionTranscript.find(24185)
181
- # target_feature = source_feature.transform('scaffold')
182
- #
183
- # assert_equal('4', source_feature.seq_region.name)
184
- # assert_equal(11389212, source_feature.seq_region_start)
185
- # assert_equal(11471635, source_feature.seq_region_end)
186
- # assert_equal(-1, source_feature.seq_region_strand)
187
- # assert_equal(nil, target_feature)
188
- # end
189
- #
190
- # # <-----------------| scaffold
191
- # # | ^ ^
192
- # # | | |
193
- # # |---<===|--<=====|-----------------------------> chromosome
194
- # def test_rev_rev_full_overlap
195
- # source_gene = Gene.find(2408)
196
- # target_gene = source_gene.transform('scaffold')
197
- #
198
- # assert_equal('4', source_gene.seq_region.name)
199
- # assert_equal(8104409, source_gene.seq_region_start)
200
- # assert_equal(8496477, source_gene.seq_region_end)
201
- # assert_equal(-1, source_gene.seq_region_strand)
202
- # assert_equal('Chr4.003.10', target_gene.seq_region.name)
203
- # assert_equal(1590801, target_gene.seq_region_start)
204
- # assert_equal(1982869, target_gene.seq_region_end)
205
- # assert_equal(1, target_gene.seq_region_strand)
206
- # end
207
- #
208
- # # <-----------------| scaffold
209
- # # |
210
- # # |
211
- # # |---<===|-----------------------------> chromosome
212
- # def test_rev_rev_partial_overlap
213
- # source_feature = Transcript.find(14723)
214
- # target_feature = source_feature.transform('scaffold')
215
- #
216
- # assert_equal('4', source_feature.seq_region.name)
217
- # assert_equal(55713316, source_feature.seq_region_start)
218
- # assert_equal(55792273, source_feature.seq_region_end)
219
- # assert_equal(-1, source_feature.seq_region_strand)
220
- # assert_equal(nil, target_feature)
221
- # end
222
- #
223
- #end