pharmaobservatory 0.1.3 → 0.1.4

data/docs/TrialsRecord.md

@@ -0,0 +1,38 @@
+# PharmaObservatory::TrialsRecord
+
+## Properties
+
+| Name | Type | Description | Notes |
+| ---- | ---- | ----------- | ----- |
+| **object_type** | **String** |  |  |
+| **id** | **String** |  |  |
+| **record** | [**TrialsRow**](TrialsRow.md) |  |  |
+| **attributes** | [**TrialsRecordAttributes**](TrialsRecordAttributes.md) |  | [optional] |
+| **datasets** | [**Array<DatasetListing>**](DatasetListing.md) |  |  |
+| **attribution** | [**Array<DatasetAttribution>**](DatasetAttribution.md) |  | [optional] |
+| **source_credit** | **String** |  | [optional] |
+| **freshness** | [**BiomarkerCdxAssertionsResponseFreshness**](BiomarkerCdxAssertionsResponseFreshness.md) |  | [optional] |
+| **build** | [**BiomarkerCdxAssertionsResponseBuild**](BiomarkerCdxAssertionsResponseBuild.md) |  | [optional] |
+| **build_state** | [**DatasetBuildState**](DatasetBuildState.md) |  | [optional] |
+| **restriction** | **Hash<String, Object>** |  | [optional] |
+
+## Example
+
+```ruby
+require 'pharmaobservatory'
+
+instance = PharmaObservatory::TrialsRecord.new(
+  object_type: null,
+  id: null,
+  record: null,
+  attributes: null,
+  datasets: null,
+  attribution: null,
+  source_credit: null,
+  freshness: null,
+  build: null,
+  build_state: null,
+  restriction: null
+)
+```
+

data/docs/TrialsRecordAttributes.md

@@ -0,0 +1,24 @@
+# PharmaObservatory::TrialsRecordAttributes
+
+## Properties
+
+| Name | Type | Description | Notes |
+| ---- | ---- | ----------- | ----- |
+| **trial_delivery** | [**TrialDeliveryRow**](TrialDeliveryRow.md) |  | [optional] |
+| **trial_demographics** | [**TrialDemographicsRow**](TrialDemographicsRow.md) |  | [optional] |
+| **trial_enrollment_rate** | [**TrialEnrollmentRateRow**](TrialEnrollmentRateRow.md) |  | [optional] |
+| **trial_extracted_endpoints** | [**TrialExtractedEndpointsRow**](TrialExtractedEndpointsRow.md) |  | [optional] |
+
+## Example
+
+```ruby
+require 'pharmaobservatory'
+
+instance = PharmaObservatory::TrialsRecordAttributes.new(
+  trial_delivery: null,
+  trial_demographics: null,
+  trial_enrollment_rate: null,
+  trial_extracted_endpoints: null
+)
+```
+

data/docs/TrialsResponse.md

@@ -0,0 +1,58 @@
+# PharmaObservatory::TrialsResponse
+
+## Properties
+
+| Name | Type | Description | Notes |
+| ---- | ---- | ----------- | ----- |
+| **dataset** | **String** |  |  |
+| **grain** | **String** |  | [optional] |
+| **object_type** | **String** |  | [optional] |
+| **id** | **String** |  | [optional] |
+| **scope** | [**BiomarkerCdxAssertionsResponseScope**](BiomarkerCdxAssertionsResponseScope.md) |  | [optional] |
+| **columns** | [**Array<DatasetColumn>**](DatasetColumn.md) |  |  |
+| **rows** | [**Array<TrialsRow>**](TrialsRow.md) |  |  |
+| **total** | **Integer** | The exact count of the filtered rows on an ungrouped read, carried by the cursor; null when grouped. | [optional] |
+| **next_cursor** | **String** |  | [optional] |
+| **sort** | **Array<String>** |  | [optional] |
+| **filters** | **Array<Hash<String, Object>>** |  | [optional] |
+| **group_by** | **Array<String>** |  | [optional] |
+| **measures** | **Array<String>** |  | [optional] |
+| **attribution** | [**Array<DatasetAttribution>**](DatasetAttribution.md) |  | [optional] |
+| **source_credit** | **String** |  | [optional] |
+| **withheld_tiers** | **Array<String>** |  | [optional] |
+| **withheld_columns** | **Array<String>** |  | [optional] |
+| **freshness** | [**BiomarkerCdxAssertionsResponseFreshness**](BiomarkerCdxAssertionsResponseFreshness.md) |  | [optional] |
+| **build** | [**BiomarkerCdxAssertionsResponseBuild**](BiomarkerCdxAssertionsResponseBuild.md) |  | [optional] |
+| **build_state** | [**DatasetBuildState**](DatasetBuildState.md) |  | [optional] |
+| **restriction** | **Hash<String, Object>** |  | [optional] |
+
+## Example
+
+```ruby
+require 'pharmaobservatory'
+
+instance = PharmaObservatory::TrialsResponse.new(
+  dataset: null,
+  grain: null,
+  object_type: null,
+  id: null,
+  scope: null,
+  columns: null,
+  rows: null,
+  total: null,
+  next_cursor: null,
+  sort: null,
+  filters: null,
+  group_by: null,
+  measures: null,
+  attribution: null,
+  source_credit: null,
+  withheld_tiers: null,
+  withheld_columns: null,
+  freshness: null,
+  build: null,
+  build_state: null,
+  restriction: null
+)
+```
+

data/docs/TrialsRow.md

@@ -0,0 +1,116 @@
+# PharmaObservatory::TrialsRow
+
+## Properties
+
+| Name | Type | Description | Notes |
+| ---- | ---- | ----------- | ----- |
+| **trial_id** | **String** | The trial's ClinicalTrials.gov registry id (NCT, National Clinical Trial, number). | [optional] |
+| **brief_title** | **String** | The trial's brief title. | [optional] |
+| **official_title** | **String** | The trial's official title. | [optional] |
+| **study_type** | **String** | INTERVENTIONAL, OBSERVATIONAL or EXPANDED_ACCESS. | [optional] |
+| **overall_status** | **String** | The registry's overall status code (RECRUITING, COMPLETED, TERMINATED and so on). | [optional] |
+| **overall_status_summary** | **String** | A coarse status label derived from the overall status (Recruiting, Completed, Discontinued and so on). | [optional] |
+| **phase** | **String** | The registry's phase code (PHASE1, PHASE2, PHASE2/PHASE3, NA). | [optional] |
+| **phase_label** | **String** | The trial phase as a label (Phase 2, Phase 3, Observational, Not applicable). | [optional] |
+| **phase_by_status** | **String** | The phase code and the status summary joined with a colon (PHASE2:Completed). | [optional] |
+| **enrollment** | **Integer** | Enrollment as registered: a planned target or an achieved count (see enrollment_type). | [optional] |
+| **enrollment_type** | **String** | ACTUAL (a count of enrolled participants) or ESTIMATED (a planned target). | [optional] |
+| **enrollment_is_plausible** | **Boolean** | False when the registered enrollment is a placeholder value rather than a count. | [optional] |
+| **enrollment_flag_reason** | **String** | Why the registered enrollment was marked a placeholder (null when it was not). | [optional] |
+| **start_date** | **Date** | Trial start date. | [optional] |
+| **start_year** | **Integer** | Year of the trial start. | [optional] |
+| **primary_completion_date** | **Date** | Primary completion date. | [optional] |
+| **primary_completion_date_type** | **String** | ACTUAL (a date that has occurred) or ESTIMATED (a planned date). | [optional] |
+| **completion_date** | **Date** | Completion date. | [optional] |
+| **completion_date_type** | **String** | ACTUAL (a date that has occurred) or ESTIMATED (a planned date). | [optional] |
+| **study_first_posted_date** | **Date** | Date the study was first posted to the registry. | [optional] |
+| **last_update_posted_date** | **Date** | Date the registry record was last updated. | [optional] |
+| **why_stopped** | **String** | The sponsor's stated reason a trial was stopped early, as filed. | [optional] |
+| **number_of_arms** | **Integer** | Number of study arms. | [optional] |
+| **were_results_reported** | **Boolean** | Whether results are posted to the registry. | [optional] |
+| **gender** | **String** | Eligible sex: ALL, FEMALE or MALE. | [optional] |
+| **minimum_age** | **String** | Minimum eligible age, as filed (for example 18 Years). | [optional] |
+| **maximum_age** | **String** | Maximum eligible age, as filed (for example 65 Years). | [optional] |
+| **healthy_volunteers** | **Boolean** | Whether healthy volunteers are accepted. | [optional] |
+| **eligibility_criteria** | **String** | The inclusion and exclusion criteria text, as filed. | [optional] |
+| **lead_sponsor_name** | **String** | The lead sponsor name as filed. | [optional] |
+| **lead_sponsor_org_id** | **String** | Legal-entity level: the organization record the lead sponsor resolved to (null when unresolved). | [optional] |
+| **lead_sponsor_company_id** | **String** | Company level: the company the lead sponsor belongs to (null when unresolved). | [optional] |
+| **lead_sponsor_company_name** | **String** | Display name of the lead sponsor's company. | [optional] |
+| **lead_sponsor_group_id** | **String** | Group level: the lead sponsor's current ultimate parent company; a root company's group is itself. | [optional] |
+| **lead_sponsor_group_name** | **String** | Display name of the lead sponsor's group. | [optional] |
+| **collaborators** | **Array<String>** | Collaborating sponsor names, as filed. | [optional] |
+| **participating_sponsors** | **Array<String>** | Names of the lead sponsor and the collaborators, as filed. | [optional] |
+| **conditions** | **Array<String>** | Conditions studied, as registered. | [optional] |
+| **condition_mesh** | **Array<String>** | Conditions studied, as Medical Subject Headings (MeSH) terms the registry assigns. | [optional] |
+| **interventions** | **Array<String>** | Interventions, as registered. | [optional] |
+| **intervention_mesh** | **Array<String>** | Interventions as Medical Subject Headings (MeSH) terms the registry assigns. | [optional] |
+| **intervention_types** | **Array<String>** | Intervention types (DRUG, BIOLOGICAL, DEVICE and so on). | [optional] |
+| **number_of_facilities** | **Integer** | Number of study sites the registry record states. | [optional] |
+| **facility_count** | **Integer** | Number of study sites listed on the record. | [optional] |
+| **has_us_facility** | **Boolean** | Whether any listed site is in the United States. | [optional] |
+| **facility_country_count** | **Integer** | Number of countries with a listed site. | [optional] |
+| **facility_countries** | **Array<String>** | Countries with a listed site. | [optional] |
+| **condition_ids** | **Array<String>** | MeSH condition ids the trial is linked to, direct and through the MeSH tree. Filter on one id to match the trials that carry it. | [optional] |
+| **drug_ids** | **Array<String>** | Drug ids the trial's interventions resolved to. Filter on one id to match the trials that carry it. | [optional] |
+| **sponsor_org_ids** | **Array<String>** | Organization record ids of the sponsors on the trial, lead and collaborator. Filter on one id to match the trials that carry it. | [optional] |
+
+## Example
+
+```ruby
+require 'pharmaobservatory'
+
+instance = PharmaObservatory::TrialsRow.new(
+  trial_id: null,
+  brief_title: null,
+  official_title: null,
+  study_type: null,
+  overall_status: null,
+  overall_status_summary: null,
+  phase: null,
+  phase_label: null,
+  phase_by_status: null,
+  enrollment: null,
+  enrollment_type: null,
+  enrollment_is_plausible: null,
+  enrollment_flag_reason: null,
+  start_date: null,
+  start_year: null,
+  primary_completion_date: null,
+  primary_completion_date_type: null,
+  completion_date: null,
+  completion_date_type: null,
+  study_first_posted_date: null,
+  last_update_posted_date: null,
+  why_stopped: null,
+  number_of_arms: null,
+  were_results_reported: null,
+  gender: null,
+  minimum_age: null,
+  maximum_age: null,
+  healthy_volunteers: null,
+  eligibility_criteria: null,
+  lead_sponsor_name: null,
+  lead_sponsor_org_id: null,
+  lead_sponsor_company_id: null,
+  lead_sponsor_company_name: null,
+  lead_sponsor_group_id: null,
+  lead_sponsor_group_name: null,
+  collaborators: null,
+  participating_sponsors: null,
+  conditions: null,
+  condition_mesh: null,
+  interventions: null,
+  intervention_mesh: null,
+  intervention_types: null,
+  number_of_facilities: null,
+  facility_count: null,
+  has_us_facility: null,
+  facility_country_count: null,
+  facility_countries: null,
+  condition_ids: null,
+  drug_ids: null,
+  sponsor_org_ids: null
+)
+```
+

data/lib/pharmaobservatory/api/biomarkers_api.rb

@@ -439,6 +439,342 @@ module PharmaObservatory
       return data, status_code, headers
     end
 
+    # Literature-extracted relations
+    # @param id [String] 
+    # @param [Hash] opts the optional parameters
+    # @option opts [String] :cursor The next_cursor of the previous page. Opaque; it is bound to the filters and the warehouse build that issued it.
+    # @option opts [Integer] :limit Rows per page, up to 500 (default 50).
+    # @option opts [String] :sort Comma separated columns, a leading minus for descending: sort=a,-b.
+    # @option opts [String] :group_by A dimension to group by; a date takes :year, :quarter or :month.
+    # @option opts [String] :measure count, sum(col), avg(col), min(col), max(col), median(col) or count_distinct(col).
+    # @return [BiomarkerRelationsResponse]
+    def biomarkers_biomarker_relations(id, opts = {})
+      data, _status_code, _headers = biomarkers_biomarker_relations_with_http_info(id, opts)
+      data
+    end
+
+    # Literature-extracted relations
+    # @param id [String] 
+    # @param [Hash] opts the optional parameters
+    # @option opts [String] :cursor The next_cursor of the previous page. Opaque; it is bound to the filters and the warehouse build that issued it.
+    # @option opts [Integer] :limit Rows per page, up to 500 (default 50).
+    # @option opts [String] :sort Comma separated columns, a leading minus for descending: sort=a,-b.
+    # @option opts [String] :group_by A dimension to group by; a date takes :year, :quarter or :month.
+    # @option opts [String] :measure count, sum(col), avg(col), min(col), max(col), median(col) or count_distinct(col).
+    # @return [Array<(BiomarkerRelationsResponse, Integer, Hash)>] BiomarkerRelationsResponse data, response status code and response headers
+    def biomarkers_biomarker_relations_with_http_info(id, opts = {})
+      if @api_client.config.debugging
+        @api_client.config.logger.debug 'Calling API: BiomarkersApi.biomarkers_biomarker_relations ...'
+      end
+      # verify the required parameter 'id' is set
+      if @api_client.config.client_side_validation && id.nil?
+        fail ArgumentError, "Missing the required parameter 'id' when calling BiomarkersApi.biomarkers_biomarker_relations"
+      end
+      if @api_client.config.client_side_validation && !opts[:'limit'].nil? && opts[:'limit'] > 500
+        fail ArgumentError, 'invalid value for "opts[:"limit"]" when calling BiomarkersApi.biomarkers_biomarker_relations, must be smaller than or equal to 500.'
+      end
+
+      if @api_client.config.client_side_validation && !opts[:'limit'].nil? && opts[:'limit'] < 1
+        fail ArgumentError, 'invalid value for "opts[:"limit"]" when calling BiomarkersApi.biomarkers_biomarker_relations, must be greater than or equal to 1.'
+      end
+
+      # resource path
+      local_var_path = '/api/v1/biomarkers/{id}/biomarker_relations'.sub('{' + 'id' + '}', CGI.escape(id.to_s))
+
+      # query parameters
+      query_params = opts[:query_params] || {}
+      query_params[:'cursor'] = opts[:'cursor'] if !opts[:'cursor'].nil?
+      query_params[:'limit'] = opts[:'limit'] if !opts[:'limit'].nil?
+      query_params[:'sort'] = opts[:'sort'] if !opts[:'sort'].nil?
+      query_params[:'group_by'] = opts[:'group_by'] if !opts[:'group_by'].nil?
+      query_params[:'measure'] = opts[:'measure'] if !opts[:'measure'].nil?
+
+      # header parameters
+      header_params = opts[:header_params] || {}
+      # HTTP header 'Accept' (if needed)
+      header_params['Accept'] = @api_client.select_header_accept(['application/json']) unless header_params['Accept']
+
+      # form parameters
+      form_params = opts[:form_params] || {}
+
+      # http body (model)
+      post_body = opts[:debug_body]
+
+      # return_type
+      return_type = opts[:debug_return_type] || 'BiomarkerRelationsResponse'
+
+      # auth_names
+      auth_names = opts[:debug_auth_names] || ['ApiBearerJwt']
+
+      new_options = opts.merge(
+        :operation => :"BiomarkersApi.biomarkers_biomarker_relations",
+        :header_params => header_params,
+        :query_params => query_params,
+        :form_params => form_params,
+        :body => post_body,
+        :auth_names => auth_names,
+        :return_type => return_type
+      )
+
+      data, status_code, headers = @api_client.call_api(:GET, local_var_path, new_options)
+      if @api_client.config.debugging
+        @api_client.config.logger.debug "API called: BiomarkersApi#biomarkers_biomarker_relations\nData: #{data.inspect}\nStatus code: #{status_code}\nHeaders: #{headers}"
+      end
+      return data, status_code, headers
+    end
+
+    # Human sample screening coverage (GDC)
+    # @param id [String] 
+    # @param [Hash] opts the optional parameters
+    # @option opts [String] :cursor The next_cursor of the previous page. Opaque; it is bound to the filters and the warehouse build that issued it.
+    # @option opts [Integer] :limit Rows per page, up to 500 (default 50).
+    # @option opts [String] :sort Comma separated columns, a leading minus for descending: sort&#x3D;a,-b.
+    # @option opts [String] :group_by A dimension to group by; a date takes :year, :quarter or :month.
+    # @option opts [String] :measure count, sum(col), avg(col), min(col), max(col), median(col) or count_distinct(col).
+    # @return [BiomarkerSampleCoverageResponse]
+    def biomarkers_biomarker_sample_coverage(id, opts = {})
+      data, _status_code, _headers = biomarkers_biomarker_sample_coverage_with_http_info(id, opts)
+      data
+    end
+
+    # Human sample screening coverage (GDC)
+    # @param id [String] 
+    # @param [Hash] opts the optional parameters
+    # @option opts [String] :cursor The next_cursor of the previous page. Opaque; it is bound to the filters and the warehouse build that issued it.
+    # @option opts [Integer] :limit Rows per page, up to 500 (default 50).
+    # @option opts [String] :sort Comma separated columns, a leading minus for descending: sort&#x3D;a,-b.
+    # @option opts [String] :group_by A dimension to group by; a date takes :year, :quarter or :month.
+    # @option opts [String] :measure count, sum(col), avg(col), min(col), max(col), median(col) or count_distinct(col).
+    # @return [Array<(BiomarkerSampleCoverageResponse, Integer, Hash)>] BiomarkerSampleCoverageResponse data, response status code and response headers
+    def biomarkers_biomarker_sample_coverage_with_http_info(id, opts = {})
+      if @api_client.config.debugging
+        @api_client.config.logger.debug 'Calling API: BiomarkersApi.biomarkers_biomarker_sample_coverage ...'
+      end
+      # verify the required parameter 'id' is set
+      if @api_client.config.client_side_validation && id.nil?
+        fail ArgumentError, "Missing the required parameter 'id' when calling BiomarkersApi.biomarkers_biomarker_sample_coverage"
+      end
+      if @api_client.config.client_side_validation && !opts[:'limit'].nil? && opts[:'limit'] > 500
+        fail ArgumentError, 'invalid value for "opts[:"limit"]" when calling BiomarkersApi.biomarkers_biomarker_sample_coverage, must be smaller than or equal to 500.'
+      end
+
+      if @api_client.config.client_side_validation && !opts[:'limit'].nil? && opts[:'limit'] < 1
+        fail ArgumentError, 'invalid value for "opts[:"limit"]" when calling BiomarkersApi.biomarkers_biomarker_sample_coverage, must be greater than or equal to 1.'
+      end
+
+      # resource path
+      local_var_path = '/api/v1/biomarkers/{id}/biomarker_sample_coverage'.sub('{' + 'id' + '}', CGI.escape(id.to_s))
+
+      # query parameters
+      query_params = opts[:query_params] || {}
+      query_params[:'cursor'] = opts[:'cursor'] if !opts[:'cursor'].nil?
+      query_params[:'limit'] = opts[:'limit'] if !opts[:'limit'].nil?
+      query_params[:'sort'] = opts[:'sort'] if !opts[:'sort'].nil?
+      query_params[:'group_by'] = opts[:'group_by'] if !opts[:'group_by'].nil?
+      query_params[:'measure'] = opts[:'measure'] if !opts[:'measure'].nil?
+
+      # header parameters
+      header_params = opts[:header_params] || {}
+      # HTTP header 'Accept' (if needed)
+      header_params['Accept'] = @api_client.select_header_accept(['application/json']) unless header_params['Accept']
+
+      # form parameters
+      form_params = opts[:form_params] || {}
+
+      # http body (model)
+      post_body = opts[:debug_body]
+
+      # return_type
+      return_type = opts[:debug_return_type] || 'BiomarkerSampleCoverageResponse'
+
+      # auth_names
+      auth_names = opts[:debug_auth_names] || ['ApiBearerJwt']
+
+      new_options = opts.merge(
+        :operation => :"BiomarkersApi.biomarkers_biomarker_sample_coverage",
+        :header_params => header_params,
+        :query_params => query_params,
+        :form_params => form_params,
+        :body => post_body,
+        :auth_names => auth_names,
+        :return_type => return_type
+      )
+
+      data, status_code, headers = @api_client.call_api(:GET, local_var_path, new_options)
+      if @api_client.config.debugging
+        @api_client.config.logger.debug "API called: BiomarkersApi#biomarkers_biomarker_sample_coverage\nData: #{data.inspect}\nStatus code: #{status_code}\nHeaders: #{headers}"
+      end
+      return data, status_code, headers
+    end
+
+    # Human sample screening reference (GDC cohorts)
+    # @param id [String] 
+    # @param [Hash] opts the optional parameters
+    # @option opts [String] :cursor The next_cursor of the previous page. Opaque; it is bound to the filters and the warehouse build that issued it.
+    # @option opts [Integer] :limit Rows per page, up to 500 (default 50).
+    # @option opts [String] :sort Comma separated columns, a leading minus for descending: sort&#x3D;a,-b.
+    # @option opts [String] :group_by A dimension to group by; a date takes :year, :quarter or :month.
+    # @option opts [String] :measure count, sum(col), avg(col), min(col), max(col), median(col) or count_distinct(col).
+    # @return [BiomarkerSamplePrevalenceResponse]
+    def biomarkers_biomarker_sample_prevalence(id, opts = {})
+      data, _status_code, _headers = biomarkers_biomarker_sample_prevalence_with_http_info(id, opts)
+      data
+    end
+
+    # Human sample screening reference (GDC cohorts)
+    # @param id [String] 
+    # @param [Hash] opts the optional parameters
+    # @option opts [String] :cursor The next_cursor of the previous page. Opaque; it is bound to the filters and the warehouse build that issued it.
+    # @option opts [Integer] :limit Rows per page, up to 500 (default 50).
+    # @option opts [String] :sort Comma separated columns, a leading minus for descending: sort&#x3D;a,-b.
+    # @option opts [String] :group_by A dimension to group by; a date takes :year, :quarter or :month.
+    # @option opts [String] :measure count, sum(col), avg(col), min(col), max(col), median(col) or count_distinct(col).
+    # @return [Array<(BiomarkerSamplePrevalenceResponse, Integer, Hash)>] BiomarkerSamplePrevalenceResponse data, response status code and response headers
+    def biomarkers_biomarker_sample_prevalence_with_http_info(id, opts = {})
+      if @api_client.config.debugging
+        @api_client.config.logger.debug 'Calling API: BiomarkersApi.biomarkers_biomarker_sample_prevalence ...'
+      end
+      # verify the required parameter 'id' is set
+      if @api_client.config.client_side_validation && id.nil?
+        fail ArgumentError, "Missing the required parameter 'id' when calling BiomarkersApi.biomarkers_biomarker_sample_prevalence"
+      end
+      if @api_client.config.client_side_validation && !opts[:'limit'].nil? && opts[:'limit'] > 500
+        fail ArgumentError, 'invalid value for "opts[:"limit"]" when calling BiomarkersApi.biomarkers_biomarker_sample_prevalence, must be smaller than or equal to 500.'
+      end
+
+      if @api_client.config.client_side_validation && !opts[:'limit'].nil? && opts[:'limit'] < 1
+        fail ArgumentError, 'invalid value for "opts[:"limit"]" when calling BiomarkersApi.biomarkers_biomarker_sample_prevalence, must be greater than or equal to 1.'
+      end
+
+      # resource path
+      local_var_path = '/api/v1/biomarkers/{id}/biomarker_sample_prevalence'.sub('{' + 'id' + '}', CGI.escape(id.to_s))
+
+      # query parameters
+      query_params = opts[:query_params] || {}
+      query_params[:'cursor'] = opts[:'cursor'] if !opts[:'cursor'].nil?
+      query_params[:'limit'] = opts[:'limit'] if !opts[:'limit'].nil?
+      query_params[:'sort'] = opts[:'sort'] if !opts[:'sort'].nil?
+      query_params[:'group_by'] = opts[:'group_by'] if !opts[:'group_by'].nil?
+      query_params[:'measure'] = opts[:'measure'] if !opts[:'measure'].nil?
+
+      # header parameters
+      header_params = opts[:header_params] || {}
+      # HTTP header 'Accept' (if needed)
+      header_params['Accept'] = @api_client.select_header_accept(['application/json']) unless header_params['Accept']
+
+      # form parameters
+      form_params = opts[:form_params] || {}
+
+      # http body (model)
+      post_body = opts[:debug_body]
+
+      # return_type
+      return_type = opts[:debug_return_type] || 'BiomarkerSamplePrevalenceResponse'
+
+      # auth_names
+      auth_names = opts[:debug_auth_names] || ['ApiBearerJwt']
+
+      new_options = opts.merge(
+        :operation => :"BiomarkersApi.biomarkers_biomarker_sample_prevalence",
+        :header_params => header_params,
+        :query_params => query_params,
+        :form_params => form_params,
+        :body => post_body,
+        :auth_names => auth_names,
+        :return_type => return_type
+      )
+
+      data, status_code, headers = @api_client.call_api(:GET, local_var_path, new_options)
+      if @api_client.config.debugging
+        @api_client.config.logger.debug "API called: BiomarkersApi#biomarkers_biomarker_sample_prevalence\nData: #{data.inspect}\nStatus code: #{status_code}\nHeaders: #{headers}"
+      end
+      return data, status_code, headers
+    end
+
+    # Biomarker validation ladder
+    # @param id [String] 
+    # @param [Hash] opts the optional parameters
+    # @option opts [String] :cursor The next_cursor of the previous page. Opaque; it is bound to the filters and the warehouse build that issued it.
+    # @option opts [Integer] :limit Rows per page, up to 500 (default 50).
+    # @option opts [String] :sort Comma separated columns, a leading minus for descending: sort&#x3D;a,-b.
+    # @option opts [String] :group_by A dimension to group by; a date takes :year, :quarter or :month.
+    # @option opts [String] :measure count, sum(col), avg(col), min(col), max(col), median(col) or count_distinct(col).
+    # @return [BiomarkerValidationResponse]
+    def biomarkers_biomarker_validation(id, opts = {})
+      data, _status_code, _headers = biomarkers_biomarker_validation_with_http_info(id, opts)
+      data
+    end
+
+    # Biomarker validation ladder
+    # @param id [String] 
+    # @param [Hash] opts the optional parameters
+    # @option opts [String] :cursor The next_cursor of the previous page. Opaque; it is bound to the filters and the warehouse build that issued it.
+    # @option opts [Integer] :limit Rows per page, up to 500 (default 50).
+    # @option opts [String] :sort Comma separated columns, a leading minus for descending: sort&#x3D;a,-b.
+    # @option opts [String] :group_by A dimension to group by; a date takes :year, :quarter or :month.
+    # @option opts [String] :measure count, sum(col), avg(col), min(col), max(col), median(col) or count_distinct(col).
+    # @return [Array<(BiomarkerValidationResponse, Integer, Hash)>] BiomarkerValidationResponse data, response status code and response headers
+    def biomarkers_biomarker_validation_with_http_info(id, opts = {})
+      if @api_client.config.debugging
+        @api_client.config.logger.debug 'Calling API: BiomarkersApi.biomarkers_biomarker_validation ...'
+      end
+      # verify the required parameter 'id' is set
+      if @api_client.config.client_side_validation && id.nil?
+        fail ArgumentError, "Missing the required parameter 'id' when calling BiomarkersApi.biomarkers_biomarker_validation"
+      end
+      if @api_client.config.client_side_validation && !opts[:'limit'].nil? && opts[:'limit'] > 500
+        fail ArgumentError, 'invalid value for "opts[:"limit"]" when calling BiomarkersApi.biomarkers_biomarker_validation, must be smaller than or equal to 500.'
+      end
+
+      if @api_client.config.client_side_validation && !opts[:'limit'].nil? && opts[:'limit'] < 1
+        fail ArgumentError, 'invalid value for "opts[:"limit"]" when calling BiomarkersApi.biomarkers_biomarker_validation, must be greater than or equal to 1.'
+      end
+
+      # resource path
+      local_var_path = '/api/v1/biomarkers/{id}/biomarker_validation'.sub('{' + 'id' + '}', CGI.escape(id.to_s))
+
+      # query parameters
+      query_params = opts[:query_params] || {}
+      query_params[:'cursor'] = opts[:'cursor'] if !opts[:'cursor'].nil?
+      query_params[:'limit'] = opts[:'limit'] if !opts[:'limit'].nil?
+      query_params[:'sort'] = opts[:'sort'] if !opts[:'sort'].nil?
+      query_params[:'group_by'] = opts[:'group_by'] if !opts[:'group_by'].nil?
+      query_params[:'measure'] = opts[:'measure'] if !opts[:'measure'].nil?
+
+      # header parameters
+      header_params = opts[:header_params] || {}
+      # HTTP header 'Accept' (if needed)
+      header_params['Accept'] = @api_client.select_header_accept(['application/json']) unless header_params['Accept']
+
+      # form parameters
+      form_params = opts[:form_params] || {}
+
+      # http body (model)
+      post_body = opts[:debug_body]
+
+      # return_type
+      return_type = opts[:debug_return_type] || 'BiomarkerValidationResponse'
+
+      # auth_names
+      auth_names = opts[:debug_auth_names] || ['ApiBearerJwt']
+
+      new_options = opts.merge(
+        :operation => :"BiomarkersApi.biomarkers_biomarker_validation",
+        :header_params => header_params,
+        :query_params => query_params,
+        :form_params => form_params,
+        :body => post_body,
+        :auth_names => auth_names,
+        :return_type => return_type
+      )
+
+      data, status_code, headers = @api_client.call_api(:GET, local_var_path, new_options)
+      if @api_client.config.debugging
+        @api_client.config.logger.debug "API called: BiomarkersApi#biomarkers_biomarker_validation\nData: #{data.inspect}\nStatus code: #{status_code}\nHeaders: #{headers}"
+      end
+      return data, status_code, headers
+    end
+
     # Protein variant mentions
     # @param id [String] 
     # @param [Hash] opts the optional parameters