google-api-client 0.12.0 → 0.13.0

data/generated/google/apis/genomics_v1/service.rb

@@ -51,11 +51,11 @@ module Google
         # for the associated annotation set.
         # @param [String] annotation_set_id
         #   The ID of the annotation set to be deleted.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -68,13 +68,13 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def delete_annotationset(annotation_set_id, fields: nil, quota_user: nil, options: nil, &block)
+        def delete_annotationset(annotation_set_id, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:delete, 'v1/annotationsets/{annotationSetId}', options)
           command.response_representation = Google::Apis::GenomicsV1::Empty::Representation
           command.response_class = Google::Apis::GenomicsV1::Empty
           command.params['annotationSetId'] = annotation_set_id unless annotation_set_id.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -84,11 +84,11 @@ module Google
         # sets in the same order across their respective streams of paginated
         # responses. Caller must have READ permission for the queried datasets.
         # @param [Google::Apis::GenomicsV1::SearchAnnotationSetsRequest] search_annotation_sets_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -101,14 +101,14 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def search_annotationset_annotation_sets(search_annotation_sets_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
+        def search_annotationset_annotation_sets(search_annotation_sets_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:post, 'v1/annotationsets/search', options)
           command.request_representation = Google::Apis::GenomicsV1::SearchAnnotationSetsRequest::Representation
           command.request_object = search_annotation_sets_request_object
           command.response_representation = Google::Apis::GenomicsV1::SearchAnnotationSetsResponse::Representation
           command.response_class = Google::Apis::GenomicsV1::SearchAnnotationSetsResponse
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -116,11 +116,11 @@ module Google
         # the associated dataset.
         # @param [String] annotation_set_id
         #   The ID of the annotation set to be retrieved.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -133,13 +133,13 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def get_annotationset(annotation_set_id, fields: nil, quota_user: nil, options: nil, &block)
+        def get_annotation_set(annotation_set_id, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:get, 'v1/annotationsets/{annotationSetId}', options)
           command.response_representation = Google::Apis::GenomicsV1::AnnotationSet::Representation
           command.response_class = Google::Apis::GenomicsV1::AnnotationSet
           command.params['annotationSetId'] = annotation_set_id unless annotation_set_id.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -155,11 +155,11 @@ module Google
         #   source_uri, and
         #   info. If unspecified, all
         #   mutable fields will be updated.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -172,7 +172,7 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def update_annotationset(annotation_set_id, annotation_set_object = nil, update_mask: nil, fields: nil, quota_user: nil, options: nil, &block)
+        def update_annotationset(annotation_set_id, annotation_set_object = nil, update_mask: nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:put, 'v1/annotationsets/{annotationSetId}', options)
           command.request_representation = Google::Apis::GenomicsV1::AnnotationSet::Representation
           command.request_object = annotation_set_object
@@ -180,8 +180,8 @@ module Google
           command.response_class = Google::Apis::GenomicsV1::AnnotationSet
           command.params['annotationSetId'] = annotation_set_id unless annotation_set_id.nil?
           command.query['updateMask'] = update_mask unless update_mask.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -193,11 +193,11 @@ module Google
         # All other fields may be optionally specified, unless documented as being
         # server-generated (for example, the `id` field).
         # @param [Google::Apis::GenomicsV1::AnnotationSet] annotation_set_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -210,204 +210,14 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def create_annotationset(annotation_set_object = nil, fields: nil, quota_user: nil, options: nil, &block)
+        def create_annotation_set(annotation_set_object = nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:post, 'v1/annotationsets', options)
           command.request_representation = Google::Apis::GenomicsV1::AnnotationSet::Representation
           command.request_object = annotation_set_object
           command.response_representation = Google::Apis::GenomicsV1::AnnotationSet::Representation
           command.response_class = Google::Apis::GenomicsV1::AnnotationSet
-          command.query['fields'] = fields unless fields.nil?
-          command.query['quotaUser'] = quota_user unless quota_user.nil?
-          execute_or_queue_command(command, &block)
-        end
-        
-        # Gets a list of variants matching the criteria.
-        # For the definitions of variants and other genomics resources, see
-        # [Fundamentals of Google
-        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # Implements
-        # [GlobalAllianceApi.searchVariants](https://github.com/ga4gh/schemas/blob/v0.5.
-        # 1/src/main/resources/avro/variantmethods.avdl#L126).
-        # @param [Google::Apis::GenomicsV1::SearchVariantsRequest] search_variants_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
-        # @param [String] quota_user
-        #   Available to use for quota purposes for server-side applications. Can be any
-        #   arbitrary string assigned to a user, but should not exceed 40 characters.
-        # @param [Google::Apis::RequestOptions] options
-        #   Request-specific options
-        #
-        # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::SearchVariantsResponse] parsed result object
-        # @yieldparam err [StandardError] error object if request failed
-        #
-        # @return [Google::Apis::GenomicsV1::SearchVariantsResponse]
-        #
-        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
-        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
-        # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def search_variants(search_variants_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/variants/search', options)
-          command.request_representation = Google::Apis::GenomicsV1::SearchVariantsRequest::Representation
-          command.request_object = search_variants_request_object
-          command.response_representation = Google::Apis::GenomicsV1::SearchVariantsResponse::Representation
-          command.response_class = Google::Apis::GenomicsV1::SearchVariantsResponse
-          command.query['fields'] = fields unless fields.nil?
-          command.query['quotaUser'] = quota_user unless quota_user.nil?
-          execute_or_queue_command(command, &block)
-        end
-        
-        # Gets a variant by ID.
-        # For the definitions of variants and other genomics resources, see
-        # [Fundamentals of Google
-        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # @param [String] variant_id
-        #   The ID of the variant.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
-        # @param [String] quota_user
-        #   Available to use for quota purposes for server-side applications. Can be any
-        #   arbitrary string assigned to a user, but should not exceed 40 characters.
-        # @param [Google::Apis::RequestOptions] options
-        #   Request-specific options
-        #
-        # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::Variant] parsed result object
-        # @yieldparam err [StandardError] error object if request failed
-        #
-        # @return [Google::Apis::GenomicsV1::Variant]
-        #
-        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
-        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
-        # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def get_variant(variant_id, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:get, 'v1/variants/{variantId}', options)
-          command.response_representation = Google::Apis::GenomicsV1::Variant::Representation
-          command.response_class = Google::Apis::GenomicsV1::Variant
-          command.params['variantId'] = variant_id unless variant_id.nil?
-          command.query['fields'] = fields unless fields.nil?
-          command.query['quotaUser'] = quota_user unless quota_user.nil?
-          execute_or_queue_command(command, &block)
-        end
-        
-        # Updates a variant.
-        # For the definitions of variants and other genomics resources, see
-        # [Fundamentals of Google
-        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # This method supports patch semantics. Returns the modified variant without
-        # its calls.
-        # @param [String] variant_id
-        #   The ID of the variant to be updated.
-        # @param [Google::Apis::GenomicsV1::Variant] variant_object
-        # @param [String] update_mask
-        #   An optional mask specifying which fields to update. At this time, mutable
-        #   fields are names and
-        #   info. Acceptable values are "names" and
-        #   "info". If unspecified, all mutable fields will be updated.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
-        # @param [String] quota_user
-        #   Available to use for quota purposes for server-side applications. Can be any
-        #   arbitrary string assigned to a user, but should not exceed 40 characters.
-        # @param [Google::Apis::RequestOptions] options
-        #   Request-specific options
-        #
-        # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::Variant] parsed result object
-        # @yieldparam err [StandardError] error object if request failed
-        #
-        # @return [Google::Apis::GenomicsV1::Variant]
-        #
-        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
-        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
-        # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def patch_variant(variant_id, variant_object = nil, update_mask: nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:patch, 'v1/variants/{variantId}', options)
-          command.request_representation = Google::Apis::GenomicsV1::Variant::Representation
-          command.request_object = variant_object
-          command.response_representation = Google::Apis::GenomicsV1::Variant::Representation
-          command.response_class = Google::Apis::GenomicsV1::Variant
-          command.params['variantId'] = variant_id unless variant_id.nil?
-          command.query['updateMask'] = update_mask unless update_mask.nil?
-          command.query['fields'] = fields unless fields.nil?
-          command.query['quotaUser'] = quota_user unless quota_user.nil?
-          execute_or_queue_command(command, &block)
-        end
-        
-        # Deletes a variant.
-        # For the definitions of variants and other genomics resources, see
-        # [Fundamentals of Google
-        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # @param [String] variant_id
-        #   The ID of the variant to be deleted.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
-        # @param [String] quota_user
-        #   Available to use for quota purposes for server-side applications. Can be any
-        #   arbitrary string assigned to a user, but should not exceed 40 characters.
-        # @param [Google::Apis::RequestOptions] options
-        #   Request-specific options
-        #
-        # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::Empty] parsed result object
-        # @yieldparam err [StandardError] error object if request failed
-        #
-        # @return [Google::Apis::GenomicsV1::Empty]
-        #
-        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
-        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
-        # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def delete_variant(variant_id, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:delete, 'v1/variants/{variantId}', options)
-          command.response_representation = Google::Apis::GenomicsV1::Empty::Representation
-          command.response_class = Google::Apis::GenomicsV1::Empty
-          command.params['variantId'] = variant_id unless variant_id.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
-          execute_or_queue_command(command, &block)
-        end
-        
-        # Creates variant data by asynchronously importing the provided information.
-        # For the definitions of variant sets and other genomics resources, see
-        # [Fundamentals of Google
-        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # The variants for import will be merged with any existing variant that
-        # matches its reference sequence, start, end, reference bases, and
-        # alternative bases. If no such variant exists, a new one will be created.
-        # When variants are merged, the call information from the new variant
-        # is added to the existing variant, and Variant info fields are merged
-        # as specified in
-        # infoMergeConfig.
-        # As a special case, for single-sample VCF files, QUAL and FILTER fields will
-        # be moved to the call level; these are sometimes interpreted in a
-        # call-specific context.
-        # Imported VCF headers are appended to the metadata already in a variant set.
-        # @param [Google::Apis::GenomicsV1::ImportVariantsRequest] import_variants_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
-        # @param [String] quota_user
-        #   Available to use for quota purposes for server-side applications. Can be any
-        #   arbitrary string assigned to a user, but should not exceed 40 characters.
-        # @param [Google::Apis::RequestOptions] options
-        #   Request-specific options
-        #
-        # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::Operation] parsed result object
-        # @yieldparam err [StandardError] error object if request failed
-        #
-        # @return [Google::Apis::GenomicsV1::Operation]
-        #
-        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
-        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
-        # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def import_variants(import_variants_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/variants:import', options)
-          command.request_representation = Google::Apis::GenomicsV1::ImportVariantsRequest::Representation
-          command.request_object = import_variants_request_object
-          command.response_representation = Google::Apis::GenomicsV1::Operation::Representation
-          command.response_class = Google::Apis::GenomicsV1::Operation
           command.query['fields'] = fields unless fields.nil?
-          command.query['quotaUser'] = quota_user unless quota_user.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -494,11 +304,11 @@ module Google
         # This may be the desired outcome, but it is up to the user to determine if
         # if that is indeed the case.
         # @param [Google::Apis::GenomicsV1::MergeVariantsRequest] merge_variants_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -511,47 +321,237 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def merge_variants(merge_variants_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
+        def merge_variants(merge_variants_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:post, 'v1/variants:merge', options)
           command.request_representation = Google::Apis::GenomicsV1::MergeVariantsRequest::Representation
           command.request_object = merge_variants_request_object
           command.response_representation = Google::Apis::GenomicsV1::Empty::Representation
           command.response_class = Google::Apis::GenomicsV1::Empty
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Creates a new variant.
-        # For the definitions of variants and other genomics resources, see
+        # Creates variant data by asynchronously importing the provided information.
+        # For the definitions of variant sets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # @param [Google::Apis::GenomicsV1::Variant] variant_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # The variants for import will be merged with any existing variant that
+        # matches its reference sequence, start, end, reference bases, and
+        # alternative bases. If no such variant exists, a new one will be created.
+        # When variants are merged, the call information from the new variant
+        # is added to the existing variant, and Variant info fields are merged
+        # as specified in
+        # infoMergeConfig.
+        # As a special case, for single-sample VCF files, QUAL and FILTER fields will
+        # be moved to the call level; these are sometimes interpreted in a
+        # call-specific context.
+        # Imported VCF headers are appended to the metadata already in a variant set.
+        # @param [Google::Apis::GenomicsV1::ImportVariantsRequest] import_variants_request_object
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::Variant] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::Operation] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::Variant]
+        # @return [Google::Apis::GenomicsV1::Operation]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def create_variant(variant_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/variants', options)
-          command.request_representation = Google::Apis::GenomicsV1::Variant::Representation
-          command.request_object = variant_object
-          command.response_representation = Google::Apis::GenomicsV1::Variant::Representation
-          command.response_class = Google::Apis::GenomicsV1::Variant
-          command.query['fields'] = fields unless fields.nil?
+        def import_variants(import_variants_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/variants:import', options)
+          command.request_representation = Google::Apis::GenomicsV1::ImportVariantsRequest::Representation
+          command.request_object = import_variants_request_object
+          command.response_representation = Google::Apis::GenomicsV1::Operation::Representation
+          command.response_class = Google::Apis::GenomicsV1::Operation
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
+          execute_or_queue_command(command, &block)
+        end
+        
+        # Deletes a variant.
+        # For the definitions of variants and other genomics resources, see
+        # [Fundamentals of Google
+        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+        # @param [String] variant_id
+        #   The ID of the variant to be deleted.
+        # @param [String] quota_user
+        #   Available to use for quota purposes for server-side applications. Can be any
+        #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
+        # @param [Google::Apis::RequestOptions] options
+        #   Request-specific options
+        #
+        # @yield [result, err] Result & error if block supplied
+        # @yieldparam result [Google::Apis::GenomicsV1::Empty] parsed result object
+        # @yieldparam err [StandardError] error object if request failed
+        #
+        # @return [Google::Apis::GenomicsV1::Empty]
+        #
+        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
+        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
+        # @raise [Google::Apis::AuthorizationError] Authorization is required
+        def delete_variant(variant_id, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:delete, 'v1/variants/{variantId}', options)
+          command.response_representation = Google::Apis::GenomicsV1::Empty::Representation
+          command.response_class = Google::Apis::GenomicsV1::Empty
+          command.params['variantId'] = variant_id unless variant_id.nil?
+          command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
+          execute_or_queue_command(command, &block)
+        end
+        
+        # Creates a new variant.
+        # For the definitions of variants and other genomics resources, see
+        # [Fundamentals of Google
+        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+        # @param [Google::Apis::GenomicsV1::Variant] variant_object
+        # @param [String] quota_user
+        #   Available to use for quota purposes for server-side applications. Can be any
+        #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
+        # @param [Google::Apis::RequestOptions] options
+        #   Request-specific options
+        #
+        # @yield [result, err] Result & error if block supplied
+        # @yieldparam result [Google::Apis::GenomicsV1::Variant] parsed result object
+        # @yieldparam err [StandardError] error object if request failed
+        #
+        # @return [Google::Apis::GenomicsV1::Variant]
+        #
+        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
+        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
+        # @raise [Google::Apis::AuthorizationError] Authorization is required
+        def create_variant(variant_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/variants', options)
+          command.request_representation = Google::Apis::GenomicsV1::Variant::Representation
+          command.request_object = variant_object
+          command.response_representation = Google::Apis::GenomicsV1::Variant::Representation
+          command.response_class = Google::Apis::GenomicsV1::Variant
+          command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
+          execute_or_queue_command(command, &block)
+        end
+        
+        # Gets a list of variants matching the criteria.
+        # For the definitions of variants and other genomics resources, see
+        # [Fundamentals of Google
+        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+        # Implements
+        # [GlobalAllianceApi.searchVariants](https://github.com/ga4gh/schemas/blob/v0.5.
+        # 1/src/main/resources/avro/variantmethods.avdl#L126).
+        # @param [Google::Apis::GenomicsV1::SearchVariantsRequest] search_variants_request_object
+        # @param [String] quota_user
+        #   Available to use for quota purposes for server-side applications. Can be any
+        #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
+        # @param [Google::Apis::RequestOptions] options
+        #   Request-specific options
+        #
+        # @yield [result, err] Result & error if block supplied
+        # @yieldparam result [Google::Apis::GenomicsV1::SearchVariantsResponse] parsed result object
+        # @yieldparam err [StandardError] error object if request failed
+        #
+        # @return [Google::Apis::GenomicsV1::SearchVariantsResponse]
+        #
+        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
+        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
+        # @raise [Google::Apis::AuthorizationError] Authorization is required
+        def search_variants(search_variants_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/variants/search', options)
+          command.request_representation = Google::Apis::GenomicsV1::SearchVariantsRequest::Representation
+          command.request_object = search_variants_request_object
+          command.response_representation = Google::Apis::GenomicsV1::SearchVariantsResponse::Representation
+          command.response_class = Google::Apis::GenomicsV1::SearchVariantsResponse
+          command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
+          execute_or_queue_command(command, &block)
+        end
+        
+        # Gets a variant by ID.
+        # For the definitions of variants and other genomics resources, see
+        # [Fundamentals of Google
+        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+        # @param [String] variant_id
+        #   The ID of the variant.
+        # @param [String] quota_user
+        #   Available to use for quota purposes for server-side applications. Can be any
+        #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
+        # @param [Google::Apis::RequestOptions] options
+        #   Request-specific options
+        #
+        # @yield [result, err] Result & error if block supplied
+        # @yieldparam result [Google::Apis::GenomicsV1::Variant] parsed result object
+        # @yieldparam err [StandardError] error object if request failed
+        #
+        # @return [Google::Apis::GenomicsV1::Variant]
+        #
+        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
+        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
+        # @raise [Google::Apis::AuthorizationError] Authorization is required
+        def get_variant(variant_id, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:get, 'v1/variants/{variantId}', options)
+          command.response_representation = Google::Apis::GenomicsV1::Variant::Representation
+          command.response_class = Google::Apis::GenomicsV1::Variant
+          command.params['variantId'] = variant_id unless variant_id.nil?
+          command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
+          execute_or_queue_command(command, &block)
+        end
+        
+        # Updates a variant.
+        # For the definitions of variants and other genomics resources, see
+        # [Fundamentals of Google
+        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+        # This method supports patch semantics. Returns the modified variant without
+        # its calls.
+        # @param [String] variant_id
+        #   The ID of the variant to be updated.
+        # @param [Google::Apis::GenomicsV1::Variant] variant_object
+        # @param [String] update_mask
+        #   An optional mask specifying which fields to update. At this time, mutable
+        #   fields are names and
+        #   info. Acceptable values are "names" and
+        #   "info". If unspecified, all mutable fields will be updated.
+        # @param [String] quota_user
+        #   Available to use for quota purposes for server-side applications. Can be any
+        #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
+        # @param [Google::Apis::RequestOptions] options
+        #   Request-specific options
+        #
+        # @yield [result, err] Result & error if block supplied
+        # @yieldparam result [Google::Apis::GenomicsV1::Variant] parsed result object
+        # @yieldparam err [StandardError] error object if request failed
+        #
+        # @return [Google::Apis::GenomicsV1::Variant]
+        #
+        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
+        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
+        # @raise [Google::Apis::AuthorizationError] Authorization is required
+        def patch_variant(variant_id, variant_object = nil, update_mask: nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:patch, 'v1/variants/{variantId}', options)
+          command.request_representation = Google::Apis::GenomicsV1::Variant::Representation
+          command.request_object = variant_object
+          command.response_representation = Google::Apis::GenomicsV1::Variant::Representation
+          command.response_class = Google::Apis::GenomicsV1::Variant
+          command.params['variantId'] = variant_id unless variant_id.nil?
+          command.query['updateMask'] = update_mask unless update_mask.nil?
+          command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -563,11 +563,11 @@ module Google
         # [GlobalAllianceApi.searchReferences](https://github.com/ga4gh/schemas/blob/v0.
         # 5.1/src/main/resources/avro/referencemethods.avdl#L146).
         # @param [Google::Apis::GenomicsV1::SearchReferencesRequest] search_references_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -580,14 +580,14 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def search_references(search_references_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
+        def search_references(search_references_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:post, 'v1/references/search', options)
           command.request_representation = Google::Apis::GenomicsV1::SearchReferencesRequest::Representation
           command.request_object = search_references_request_object
           command.response_representation = Google::Apis::GenomicsV1::SearchReferencesResponse::Representation
           command.response_class = Google::Apis::GenomicsV1::SearchReferencesResponse
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -600,11 +600,11 @@ module Google
         # src/main/resources/avro/referencemethods.avdl#L158).
         # @param [String] reference_id
         #   The ID of the reference.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -617,13 +617,13 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def get_reference(reference_id, fields: nil, quota_user: nil, options: nil, &block)
+        def get_reference(reference_id, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:get, 'v1/references/{referenceId}', options)
           command.response_representation = Google::Apis::GenomicsV1::Reference::Representation
           command.response_class = Google::Apis::GenomicsV1::Reference
           command.params['referenceId'] = reference_id unless reference_id.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -636,6 +636,9 @@ module Google
         # 5.1/src/main/resources/avro/referencemethods.avdl#L221).
         # @param [String] reference_id
         #   The ID of the reference.
+        # @param [Fixnum] end_position
+        #   The end position (0-based, exclusive) of this query. Defaults to the length
+        #   of this reference.
         # @param [String] page_token
         #   The continuation token, which is used to page through large result sets.
         #   To get the next page of results, set this parameter to the value of
@@ -644,16 +647,13 @@ module Google
         #   The maximum number of bases to return in a single page. If unspecified,
         #   defaults to 200Kbp (kilo base pairs). The maximum value is 10Mbp (mega base
         #   pairs).
-        # @param [Fixnum] start
+        # @param [Fixnum] start_position
         #   The start position (0-based) of this query. Defaults to 0.
-        # @param [Fixnum] end_
-        #   The end position (0-based, exclusive) of this query. Defaults to the length
-        #   of this reference.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -666,209 +666,90 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def list_reference_bases(reference_id, page_token: nil, page_size: nil, start: nil, end_: nil, fields: nil, quota_user: nil, options: nil, &block)
+        def list_reference_bases(reference_id, end_position: nil, page_token: nil, page_size: nil, start_position: nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:get, 'v1/references/{referenceId}/bases', options)
           command.response_representation = Google::Apis::GenomicsV1::ListBasesResponse::Representation
           command.response_class = Google::Apis::GenomicsV1::ListBasesResponse
           command.params['referenceId'] = reference_id unless reference_id.nil?
+          command.query['end'] = end_position unless end_position.nil?
           command.query['pageToken'] = page_token unless page_token.nil?
           command.query['pageSize'] = page_size unless page_size.nil?
-          command.query['start'] = start unless start.nil?
-          command.query['end'] = end_ unless end_.nil?
-          command.query['fields'] = fields unless fields.nil?
+          command.query['start'] = start_position unless start_position.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Returns permissions that a caller has on the specified resource.
-        # See <a href="/iam/docs/managing-policies#testing_permissions">Testing
-        # Permissions</a> for more information.
+        # Sets the access control policy on the specified dataset. Replaces any
+        # existing policy.
         # For the definitions of datasets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+        # See <a href="/iam/docs/managing-policies#setting_a_policy">Setting a
+        # Policy</a> for more information.
         # @param [String] resource
         #   REQUIRED: The resource for which policy is being specified. Format is
         #   `datasets/<dataset ID>`.
-        # @param [Google::Apis::GenomicsV1::TestIamPermissionsRequest] test_iam_permissions_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # @param [Google::Apis::GenomicsV1::SetIamPolicyRequest] set_iam_policy_request_object
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::TestIamPermissionsResponse] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::Policy] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::TestIamPermissionsResponse]
+        # @return [Google::Apis::GenomicsV1::Policy]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def test_dataset_iam_permissions(resource, test_iam_permissions_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/{+resource}:testIamPermissions', options)
-          command.request_representation = Google::Apis::GenomicsV1::TestIamPermissionsRequest::Representation
-          command.request_object = test_iam_permissions_request_object
-          command.response_representation = Google::Apis::GenomicsV1::TestIamPermissionsResponse::Representation
-          command.response_class = Google::Apis::GenomicsV1::TestIamPermissionsResponse
+        def set_dataset_iam_policy(resource, set_iam_policy_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/{+resource}:setIamPolicy', options)
+          command.request_representation = Google::Apis::GenomicsV1::SetIamPolicyRequest::Representation
+          command.request_object = set_iam_policy_request_object
+          command.response_representation = Google::Apis::GenomicsV1::Policy::Representation
+          command.response_class = Google::Apis::GenomicsV1::Policy
           command.params['resource'] = resource unless resource.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Deletes a dataset and all of its contents (all read group sets,
-        # reference sets, variant sets, call sets, annotation sets, etc.)
-        # This is reversible (up to one week after the deletion) via
-        # the
-        # datasets.undelete
-        # operation.
+        # Creates a new dataset.
         # For the definitions of datasets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # @param [String] dataset_id
-        #   The ID of the dataset to be deleted.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # @param [Google::Apis::GenomicsV1::Dataset] dataset_object
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::Empty] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::Dataset] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::Empty]
+        # @return [Google::Apis::GenomicsV1::Dataset]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def delete_dataset(dataset_id, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:delete, 'v1/datasets/{datasetId}', options)
-          command.response_representation = Google::Apis::GenomicsV1::Empty::Representation
-          command.response_class = Google::Apis::GenomicsV1::Empty
-          command.params['datasetId'] = dataset_id unless dataset_id.nil?
-          command.query['fields'] = fields unless fields.nil?
-          command.query['quotaUser'] = quota_user unless quota_user.nil?
-          execute_or_queue_command(command, &block)
-        end
-        
-        # Lists datasets within a project.
-        # For the definitions of datasets and other genomics resources, see
-        # [Fundamentals of Google
-        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # @param [String] page_token
-        #   The continuation token, which is used to page through large result sets.
-        #   To get the next page of results, set this parameter to the value of
-        #   `nextPageToken` from the previous response.
-        # @param [Fixnum] page_size
-        #   The maximum number of results to return in a single page. If unspecified,
-        #   defaults to 50. The maximum value is 1024.
-        # @param [String] project_id
-        #   Required. The Google Cloud project ID to list datasets for.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
-        # @param [String] quota_user
-        #   Available to use for quota purposes for server-side applications. Can be any
-        #   arbitrary string assigned to a user, but should not exceed 40 characters.
-        # @param [Google::Apis::RequestOptions] options
-        #   Request-specific options
-        #
-        # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::ListDatasetsResponse] parsed result object
-        # @yieldparam err [StandardError] error object if request failed
-        #
-        # @return [Google::Apis::GenomicsV1::ListDatasetsResponse]
-        #
-        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
-        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
-        # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def list_datasets(page_token: nil, page_size: nil, project_id: nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:get, 'v1/datasets', options)
-          command.response_representation = Google::Apis::GenomicsV1::ListDatasetsResponse::Representation
-          command.response_class = Google::Apis::GenomicsV1::ListDatasetsResponse
-          command.query['pageToken'] = page_token unless page_token.nil?
-          command.query['pageSize'] = page_size unless page_size.nil?
-          command.query['projectId'] = project_id unless project_id.nil?
-          command.query['fields'] = fields unless fields.nil?
-          command.query['quotaUser'] = quota_user unless quota_user.nil?
-          execute_or_queue_command(command, &block)
-        end
-        
-        # Sets the access control policy on the specified dataset. Replaces any
-        # existing policy.
-        # For the definitions of datasets and other genomics resources, see
-        # [Fundamentals of Google
-        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # See <a href="/iam/docs/managing-policies#setting_a_policy">Setting a
-        # Policy</a> for more information.
-        # @param [String] resource
-        #   REQUIRED: The resource for which policy is being specified. Format is
-        #   `datasets/<dataset ID>`.
-        # @param [Google::Apis::GenomicsV1::SetIamPolicyRequest] set_iam_policy_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
-        # @param [String] quota_user
-        #   Available to use for quota purposes for server-side applications. Can be any
-        #   arbitrary string assigned to a user, but should not exceed 40 characters.
-        # @param [Google::Apis::RequestOptions] options
-        #   Request-specific options
-        #
-        # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::Policy] parsed result object
-        # @yieldparam err [StandardError] error object if request failed
-        #
-        # @return [Google::Apis::GenomicsV1::Policy]
-        #
-        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
-        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
-        # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def set_dataset_iam_policy(resource, set_iam_policy_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/{+resource}:setIamPolicy', options)
-          command.request_representation = Google::Apis::GenomicsV1::SetIamPolicyRequest::Representation
-          command.request_object = set_iam_policy_request_object
-          command.response_representation = Google::Apis::GenomicsV1::Policy::Representation
-          command.response_class = Google::Apis::GenomicsV1::Policy
-          command.params['resource'] = resource unless resource.nil?
-          command.query['fields'] = fields unless fields.nil?
-          command.query['quotaUser'] = quota_user unless quota_user.nil?
-          execute_or_queue_command(command, &block)
-        end
-        
-        # Creates a new dataset.
-        # For the definitions of datasets and other genomics resources, see
-        # [Fundamentals of Google
-        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # @param [Google::Apis::GenomicsV1::Dataset] dataset_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
-        # @param [String] quota_user
-        #   Available to use for quota purposes for server-side applications. Can be any
-        #   arbitrary string assigned to a user, but should not exceed 40 characters.
-        # @param [Google::Apis::RequestOptions] options
-        #   Request-specific options
-        #
-        # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::Dataset] parsed result object
-        # @yieldparam err [StandardError] error object if request failed
-        #
-        # @return [Google::Apis::GenomicsV1::Dataset]
-        #
-        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
-        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
-        # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def create_dataset(dataset_object = nil, fields: nil, quota_user: nil, options: nil, &block)
+        def create_dataset(dataset_object = nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:post, 'v1/datasets', options)
           command.request_representation = Google::Apis::GenomicsV1::Dataset::Representation
           command.request_object = dataset_object
           command.response_representation = Google::Apis::GenomicsV1::Dataset::Representation
           command.response_class = Google::Apis::GenomicsV1::Dataset
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -883,11 +764,11 @@ module Google
         #   REQUIRED: The resource for which policy is being specified. Format is
         #   `datasets/<dataset ID>`.
         # @param [Google::Apis::GenomicsV1::GetIamPolicyRequest] get_iam_policy_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -900,15 +781,15 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def get_dataset_iam_policy(resource, get_iam_policy_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
+        def get_dataset_iam_policy(resource, get_iam_policy_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:post, 'v1/{+resource}:getIamPolicy', options)
           command.request_representation = Google::Apis::GenomicsV1::GetIamPolicyRequest::Representation
           command.request_object = get_iam_policy_request_object
           command.response_representation = Google::Apis::GenomicsV1::Policy::Representation
           command.response_class = Google::Apis::GenomicsV1::Policy
           command.params['resource'] = resource unless resource.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -925,11 +806,11 @@ module Google
         #   mutable field is name. The only
         #   acceptable value is "name". If unspecified, all mutable fields will be
         #   updated.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -942,7 +823,7 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def patch_dataset(dataset_id, dataset_object = nil, update_mask: nil, fields: nil, quota_user: nil, options: nil, &block)
+        def patch_dataset(dataset_id, dataset_object = nil, update_mask: nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:patch, 'v1/datasets/{datasetId}', options)
           command.request_representation = Google::Apis::GenomicsV1::Dataset::Representation
           command.request_object = dataset_object
@@ -950,22 +831,24 @@ module Google
           command.response_class = Google::Apis::GenomicsV1::Dataset
           command.params['datasetId'] = dataset_id unless dataset_id.nil?
           command.query['updateMask'] = update_mask unless update_mask.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Gets a dataset by ID.
+        # Undeletes a dataset by restoring a dataset which was deleted via this API.
         # For the definitions of datasets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+        # This operation is only possible for a week after the deletion occurred.
         # @param [String] dataset_id
-        #   The ID of the dataset.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        #   The ID of the dataset to be undeleted.
+        # @param [Google::Apis::GenomicsV1::UndeleteDatasetRequest] undelete_dataset_request_object
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -978,29 +861,29 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def get_dataset(dataset_id, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:get, 'v1/datasets/{datasetId}', options)
+        def undelete_dataset(dataset_id, undelete_dataset_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/datasets/{datasetId}:undelete', options)
+          command.request_representation = Google::Apis::GenomicsV1::UndeleteDatasetRequest::Representation
+          command.request_object = undelete_dataset_request_object
           command.response_representation = Google::Apis::GenomicsV1::Dataset::Representation
           command.response_class = Google::Apis::GenomicsV1::Dataset
           command.params['datasetId'] = dataset_id unless dataset_id.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Undeletes a dataset by restoring a dataset which was deleted via this API.
+        # Gets a dataset by ID.
         # For the definitions of datasets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # This operation is only possible for a week after the deletion occurred.
         # @param [String] dataset_id
-        #   The ID of the dataset to be undeleted.
-        # @param [Google::Apis::GenomicsV1::UndeleteDatasetRequest] undelete_dataset_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        #   The ID of the dataset.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1013,30 +896,71 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def undelete_dataset(dataset_id, undelete_dataset_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/datasets/{datasetId}:undelete', options)
-          command.request_representation = Google::Apis::GenomicsV1::UndeleteDatasetRequest::Representation
-          command.request_object = undelete_dataset_request_object
+        def get_dataset(dataset_id, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:get, 'v1/datasets/{datasetId}', options)
           command.response_representation = Google::Apis::GenomicsV1::Dataset::Representation
           command.response_class = Google::Apis::GenomicsV1::Dataset
           command.params['datasetId'] = dataset_id unless dataset_id.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Deletes a variant set including all variants, call sets, and calls within.
-        # This is not reversible.
-        # For the definitions of variant sets and other genomics resources, see
+        # Returns permissions that a caller has on the specified resource.
+        # See <a href="/iam/docs/managing-policies#testing_permissions">Testing
+        # Permissions</a> for more information.
+        # For the definitions of datasets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # @param [String] variant_set_id
-        #   The ID of the variant set to be deleted.
+        # @param [String] resource
+        #   REQUIRED: The resource for which policy is being specified. Format is
+        #   `datasets/<dataset ID>`.
+        # @param [Google::Apis::GenomicsV1::TestIamPermissionsRequest] test_iam_permissions_request_object
+        # @param [String] quota_user
+        #   Available to use for quota purposes for server-side applications. Can be any
+        #   arbitrary string assigned to a user, but should not exceed 40 characters.
         # @param [String] fields
         #   Selector specifying which fields to include in a partial response.
+        # @param [Google::Apis::RequestOptions] options
+        #   Request-specific options
+        #
+        # @yield [result, err] Result & error if block supplied
+        # @yieldparam result [Google::Apis::GenomicsV1::TestIamPermissionsResponse] parsed result object
+        # @yieldparam err [StandardError] error object if request failed
+        #
+        # @return [Google::Apis::GenomicsV1::TestIamPermissionsResponse]
+        #
+        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
+        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
+        # @raise [Google::Apis::AuthorizationError] Authorization is required
+        def test_dataset_iam_permissions(resource, test_iam_permissions_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/{+resource}:testIamPermissions', options)
+          command.request_representation = Google::Apis::GenomicsV1::TestIamPermissionsRequest::Representation
+          command.request_object = test_iam_permissions_request_object
+          command.response_representation = Google::Apis::GenomicsV1::TestIamPermissionsResponse::Representation
+          command.response_class = Google::Apis::GenomicsV1::TestIamPermissionsResponse
+          command.params['resource'] = resource unless resource.nil?
+          command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
+          execute_or_queue_command(command, &block)
+        end
+        
+        # Deletes a dataset and all of its contents (all read group sets,
+        # reference sets, variant sets, call sets, annotation sets, etc.)
+        # This is reversible (up to one week after the deletion) via
+        # the
+        # datasets.undelete
+        # operation.
+        # For the definitions of datasets and other genomics resources, see
+        # [Fundamentals of Google
+        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+        # @param [String] dataset_id
+        #   The ID of the dataset to be deleted.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1049,49 +973,55 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def delete_variantset(variant_set_id, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:delete, 'v1/variantsets/{variantSetId}', options)
+        def delete_dataset(dataset_id, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:delete, 'v1/datasets/{datasetId}', options)
           command.response_representation = Google::Apis::GenomicsV1::Empty::Representation
           command.response_class = Google::Apis::GenomicsV1::Empty
-          command.params['variantSetId'] = variant_set_id unless variant_set_id.nil?
-          command.query['fields'] = fields unless fields.nil?
+          command.params['datasetId'] = dataset_id unless dataset_id.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Creates a new variant set.
-        # For the definitions of variant sets and other genomics resources, see
+        # Lists datasets within a project.
+        # For the definitions of datasets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # The provided variant set must have a valid `datasetId` set - all other
-        # fields are optional. Note that the `id` field will be ignored, as this is
-        # assigned by the server.
-        # @param [Google::Apis::GenomicsV1::VariantSet] variant_set_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # @param [String] page_token
+        #   The continuation token, which is used to page through large result sets.
+        #   To get the next page of results, set this parameter to the value of
+        #   `nextPageToken` from the previous response.
+        # @param [Fixnum] page_size
+        #   The maximum number of results to return in a single page. If unspecified,
+        #   defaults to 50. The maximum value is 1024.
+        # @param [String] project_id
+        #   Required. The Google Cloud project ID to list datasets for.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::VariantSet] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::ListDatasetsResponse] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::VariantSet]
+        # @return [Google::Apis::GenomicsV1::ListDatasetsResponse]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def create_variantset(variant_set_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/variantsets', options)
-          command.request_representation = Google::Apis::GenomicsV1::VariantSet::Representation
-          command.request_object = variant_set_object
-          command.response_representation = Google::Apis::GenomicsV1::VariantSet::Representation
-          command.response_class = Google::Apis::GenomicsV1::VariantSet
-          command.query['fields'] = fields unless fields.nil?
+        def list_datasets(page_token: nil, page_size: nil, project_id: nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:get, 'v1/datasets', options)
+          command.response_representation = Google::Apis::GenomicsV1::ListDatasetsResponse::Representation
+          command.response_class = Google::Apis::GenomicsV1::ListDatasetsResponse
+          command.query['pageToken'] = page_token unless page_token.nil?
+          command.query['pageSize'] = page_size unless page_size.nil?
+          command.query['projectId'] = project_id unless project_id.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -1103,11 +1033,11 @@ module Google
         #   Required. The ID of the variant set that contains variant data which
         #   should be exported. The caller must have READ access to this variant set.
         # @param [Google::Apis::GenomicsV1::ExportVariantSetRequest] export_variant_set_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1120,15 +1050,15 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def export_variantset_variant_set(variant_set_id, export_variant_set_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
+        def export_variant_set(variant_set_id, export_variant_set_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:post, 'v1/variantsets/{variantSetId}:export', options)
           command.request_representation = Google::Apis::GenomicsV1::ExportVariantSetRequest::Representation
           command.request_object = export_variant_set_request_object
           command.response_representation = Google::Apis::GenomicsV1::Operation::Representation
           command.response_class = Google::Apis::GenomicsV1::Operation
           command.params['variantSetId'] = variant_set_id unless variant_set_id.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -1140,11 +1070,11 @@ module Google
         # [GlobalAllianceApi.searchVariantSets](https://github.com/ga4gh/schemas/blob/v0.
         # 5.1/src/main/resources/avro/variantmethods.avdl#L49).
         # @param [Google::Apis::GenomicsV1::SearchVariantSetsRequest] search_variant_sets_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1157,14 +1087,14 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def search_variantset_variant_sets(search_variant_sets_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
+        def search_variant_sets(search_variant_sets_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:post, 'v1/variantsets/search', options)
           command.request_representation = Google::Apis::GenomicsV1::SearchVariantSetsRequest::Representation
           command.request_object = search_variant_sets_request_object
           command.response_representation = Google::Apis::GenomicsV1::SearchVariantSetsResponse::Representation
           command.response_class = Google::Apis::GenomicsV1::SearchVariantSetsResponse
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -1182,11 +1112,11 @@ module Google
         #   * description.
         #   Leaving `updateMask` unset is equivalent to specifying all mutable
         #   fields.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1199,7 +1129,7 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def patch_variantset(variant_set_id, variant_set_object = nil, update_mask: nil, fields: nil, quota_user: nil, options: nil, &block)
+        def patch_variantset(variant_set_id, variant_set_object = nil, update_mask: nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:patch, 'v1/variantsets/{variantSetId}', options)
           command.request_representation = Google::Apis::GenomicsV1::VariantSet::Representation
           command.request_object = variant_set_object
@@ -1207,8 +1137,8 @@ module Google
           command.response_class = Google::Apis::GenomicsV1::VariantSet
           command.params['variantSetId'] = variant_set_id unless variant_set_id.nil?
           command.query['updateMask'] = update_mask unless update_mask.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -1218,11 +1148,11 @@ module Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
         # @param [String] variant_set_id
         #   Required. The ID of the variant set.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1235,25 +1165,28 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def get_variantset(variant_set_id, fields: nil, quota_user: nil, options: nil, &block)
+        def get_variantset(variant_set_id, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:get, 'v1/variantsets/{variantSetId}', options)
           command.response_representation = Google::Apis::GenomicsV1::VariantSet::Representation
           command.response_class = Google::Apis::GenomicsV1::VariantSet
           command.params['variantSetId'] = variant_set_id unless variant_set_id.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Deletes an annotation. Caller must have WRITE permission for
-        # the associated annotation set.
-        # @param [String] annotation_id
-        #   The ID of the annotation to be deleted.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # Deletes a variant set including all variants, call sets, and calls within.
+        # This is not reversible.
+        # For the definitions of variant sets and other genomics resources, see
+        # [Fundamentals of Google
+        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+        # @param [String] variant_set_id
+        #   The ID of the variant set to be deleted.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1266,58 +1199,49 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def delete_annotation(annotation_id, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:delete, 'v1/annotations/{annotationId}', options)
+        def delete_variantset(variant_set_id, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:delete, 'v1/variantsets/{variantSetId}', options)
           command.response_representation = Google::Apis::GenomicsV1::Empty::Representation
           command.response_class = Google::Apis::GenomicsV1::Empty
-          command.params['annotationId'] = annotation_id unless annotation_id.nil?
-          command.query['fields'] = fields unless fields.nil?
+          command.params['variantSetId'] = variant_set_id unless variant_set_id.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Creates a new annotation. Caller must have WRITE permission
-        # for the associated annotation set.
-        # The following fields are required:
-        # * annotationSetId
-        # * referenceName or
-        # referenceId
-        # ### Transcripts
-        # For annotations of type TRANSCRIPT, the following fields of
-        # transcript must be provided:
-        # * exons.start
-        # * exons.end
-        # All other fields may be optionally specified, unless documented as being
-        # server-generated (for example, the `id` field). The annotated
-        # range must be no longer than 100Mbp (mega base pairs). See the
-        # Annotation resource
-        # for additional restrictions on each field.
-        # @param [Google::Apis::GenomicsV1::Annotation] annotation_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # Creates a new variant set.
+        # For the definitions of variant sets and other genomics resources, see
+        # [Fundamentals of Google
+        # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+        # The provided variant set must have a valid `datasetId` set - all other
+        # fields are optional. Note that the `id` field will be ignored, as this is
+        # assigned by the server.
+        # @param [Google::Apis::GenomicsV1::VariantSet] variant_set_object
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::Annotation] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::VariantSet] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::Annotation]
+        # @return [Google::Apis::GenomicsV1::VariantSet]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def create_annotation(annotation_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/annotations', options)
-          command.request_representation = Google::Apis::GenomicsV1::Annotation::Representation
-          command.request_object = annotation_object
-          command.response_representation = Google::Apis::GenomicsV1::Annotation::Representation
-          command.response_class = Google::Apis::GenomicsV1::Annotation
-          command.query['fields'] = fields unless fields.nil?
+        def create_variantset(variant_set_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/variantsets', options)
+          command.request_representation = Google::Apis::GenomicsV1::VariantSet::Representation
+          command.request_object = variant_set_object
+          command.response_representation = Google::Apis::GenomicsV1::VariantSet::Representation
+          command.response_class = Google::Apis::GenomicsV1::VariantSet
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -1334,11 +1258,11 @@ module Google
         # see
         # CreateAnnotation.
         # @param [Google::Apis::GenomicsV1::BatchCreateAnnotationsRequest] batch_create_annotations_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1351,14 +1275,14 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def batch_create_annotations(batch_create_annotations_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
+        def batch_create_annotations(batch_create_annotations_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:post, 'v1/annotations:batchCreate', options)
           command.request_representation = Google::Apis::GenomicsV1::BatchCreateAnnotationsRequest::Representation
           command.request_object = batch_create_annotations_request_object
           command.response_representation = Google::Apis::GenomicsV1::BatchCreateAnnotationsResponse::Representation
           command.response_class = Google::Apis::GenomicsV1::BatchCreateAnnotationsResponse
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -1370,11 +1294,11 @@ module Google
         # across their respective streams of paginated responses. Caller must have
         # READ permission for the queried annotation sets.
         # @param [Google::Apis::GenomicsV1::SearchAnnotationsRequest] search_annotations_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1387,14 +1311,14 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def search_annotations(search_annotations_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
+        def search_annotations(search_annotations_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:post, 'v1/annotations/search', options)
           command.request_representation = Google::Apis::GenomicsV1::SearchAnnotationsRequest::Representation
           command.request_object = search_annotations_request_object
           command.response_representation = Google::Apis::GenomicsV1::SearchAnnotationsResponse::Representation
           command.response_class = Google::Apis::GenomicsV1::SearchAnnotationsResponse
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -1402,11 +1326,11 @@ module Google
         # for the associated annotation set.
         # @param [String] annotation_id
         #   The ID of the annotation to be retrieved.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1419,13 +1343,13 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def get_annotation(annotation_id, fields: nil, quota_user: nil, options: nil, &block)
+        def get_annotation(annotation_id, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:get, 'v1/annotations/{annotationId}', options)
           command.response_representation = Google::Apis::GenomicsV1::Annotation::Representation
           command.response_class = Google::Apis::GenomicsV1::Annotation
           command.params['annotationId'] = annotation_id unless annotation_id.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -1441,11 +1365,11 @@ module Google
         #   transcript, and
         #   info. If unspecified, all mutable
         #   fields will be updated.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1458,7 +1382,7 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def update_annotation(annotation_id, annotation_object = nil, update_mask: nil, fields: nil, quota_user: nil, options: nil, &block)
+        def update_annotation(annotation_id, annotation_object = nil, update_mask: nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:put, 'v1/annotations/{annotationId}', options)
           command.request_representation = Google::Apis::GenomicsV1::Annotation::Representation
           command.request_object = annotation_object
@@ -1466,23 +1390,20 @@ module Google
           command.response_class = Google::Apis::GenomicsV1::Annotation
           command.params['annotationId'] = annotation_id unless annotation_id.nil?
           command.query['updateMask'] = update_mask unless update_mask.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Starts asynchronous cancellation on a long-running operation. The server makes
-        # a best effort to cancel the operation, but success is not guaranteed. Clients
-        # may use Operations.GetOperation or Operations.ListOperations to check whether
-        # the cancellation succeeded or the operation completed despite cancellation.
-        # @param [String] name
-        #   The name of the operation resource to be cancelled.
-        # @param [Google::Apis::GenomicsV1::CancelOperationRequest] cancel_operation_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # Deletes an annotation. Caller must have WRITE permission for
+        # the associated annotation set.
+        # @param [String] annotation_id
+        #   The ID of the annotation to be deleted.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1495,21 +1416,69 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def cancel_operation(name, cancel_operation_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/{+name}:cancel', options)
-          command.request_representation = Google::Apis::GenomicsV1::CancelOperationRequest::Representation
-          command.request_object = cancel_operation_request_object
+        def delete_annotation(annotation_id, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:delete, 'v1/annotations/{annotationId}', options)
           command.response_representation = Google::Apis::GenomicsV1::Empty::Representation
           command.response_class = Google::Apis::GenomicsV1::Empty
-          command.params['name'] = name unless name.nil?
+          command.params['annotationId'] = annotation_id unless annotation_id.nil?
+          command.query['quotaUser'] = quota_user unless quota_user.nil?
           command.query['fields'] = fields unless fields.nil?
+          execute_or_queue_command(command, &block)
+        end
+        
+        # Creates a new annotation. Caller must have WRITE permission
+        # for the associated annotation set.
+        # The following fields are required:
+        # * annotationSetId
+        # * referenceName or
+        # referenceId
+        # ### Transcripts
+        # For annotations of type TRANSCRIPT, the following fields of
+        # transcript must be provided:
+        # * exons.start
+        # * exons.end
+        # All other fields may be optionally specified, unless documented as being
+        # server-generated (for example, the `id` field). The annotated
+        # range must be no longer than 100Mbp (mega base pairs). See the
+        # Annotation resource
+        # for additional restrictions on each field.
+        # @param [Google::Apis::GenomicsV1::Annotation] annotation_object
+        # @param [String] quota_user
+        #   Available to use for quota purposes for server-side applications. Can be any
+        #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
+        # @param [Google::Apis::RequestOptions] options
+        #   Request-specific options
+        #
+        # @yield [result, err] Result & error if block supplied
+        # @yieldparam result [Google::Apis::GenomicsV1::Annotation] parsed result object
+        # @yieldparam err [StandardError] error object if request failed
+        #
+        # @return [Google::Apis::GenomicsV1::Annotation]
+        #
+        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
+        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
+        # @raise [Google::Apis::AuthorizationError] Authorization is required
+        def create_annotation(annotation_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/annotations', options)
+          command.request_representation = Google::Apis::GenomicsV1::Annotation::Representation
+          command.request_object = annotation_object
+          command.response_representation = Google::Apis::GenomicsV1::Annotation::Representation
+          command.response_class = Google::Apis::GenomicsV1::Annotation
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
         # Lists operations that match the specified filter in the request.
         # @param [String] name
         #   The name of the operation's parent resource.
+        # @param [String] page_token
+        #   The standard list page token.
+        # @param [Fixnum] page_size
+        #   The maximum number of results to return. If unspecified, defaults to
+        #   256. The maximum value is 2048.
         # @param [String] filter
         #   A string for filtering Operations.
         #   The following filter fields are supported&#58;
@@ -1527,16 +1496,11 @@ module Google
         #   1432150000 AND status = RUNNING`
         #   * `projectId = my-project AND labels.color = *`
         #   * `projectId = my-project AND labels.color = red`
-        # @param [String] page_token
-        #   The standard list page token.
-        # @param [Fixnum] page_size
-        #   The maximum number of results to return. If unspecified, defaults to
-        #   256. The maximum value is 2048.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1549,16 +1513,16 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def list_operations(name, filter: nil, page_token: nil, page_size: nil, fields: nil, quota_user: nil, options: nil, &block)
+        def list_operations(name, page_token: nil, page_size: nil, filter: nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:get, 'v1/{+name}', options)
           command.response_representation = Google::Apis::GenomicsV1::ListOperationsResponse::Representation
           command.response_class = Google::Apis::GenomicsV1::ListOperationsResponse
           command.params['name'] = name unless name.nil?
-          command.query['filter'] = filter unless filter.nil?
           command.query['pageToken'] = page_token unless page_token.nil?
           command.query['pageSize'] = page_size unless page_size.nil?
-          command.query['fields'] = fields unless fields.nil?
+          command.query['filter'] = filter unless filter.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -1567,11 +1531,11 @@ module Google
         # service.
         # @param [String] name
         #   The name of the operation resource.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1584,13 +1548,49 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def get_operation(name, fields: nil, quota_user: nil, options: nil, &block)
+        def get_operation(name, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:get, 'v1/{+name}', options)
           command.response_representation = Google::Apis::GenomicsV1::Operation::Representation
           command.response_class = Google::Apis::GenomicsV1::Operation
           command.params['name'] = name unless name.nil?
+          command.query['quotaUser'] = quota_user unless quota_user.nil?
           command.query['fields'] = fields unless fields.nil?
+          execute_or_queue_command(command, &block)
+        end
+        
+        # Starts asynchronous cancellation on a long-running operation. The server makes
+        # a best effort to cancel the operation, but success is not guaranteed. Clients
+        # may use Operations.GetOperation or Operations.ListOperations to check whether
+        # the cancellation succeeded or the operation completed despite cancellation.
+        # @param [String] name
+        #   The name of the operation resource to be cancelled.
+        # @param [Google::Apis::GenomicsV1::CancelOperationRequest] cancel_operation_request_object
+        # @param [String] quota_user
+        #   Available to use for quota purposes for server-side applications. Can be any
+        #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
+        # @param [Google::Apis::RequestOptions] options
+        #   Request-specific options
+        #
+        # @yield [result, err] Result & error if block supplied
+        # @yieldparam result [Google::Apis::GenomicsV1::Empty] parsed result object
+        # @yieldparam err [StandardError] error object if request failed
+        #
+        # @return [Google::Apis::GenomicsV1::Empty]
+        #
+        # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
+        # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
+        # @raise [Google::Apis::AuthorizationError] Authorization is required
+        def cancel_operation(name, cancel_operation_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/{+name}:cancel', options)
+          command.request_representation = Google::Apis::GenomicsV1::CancelOperationRequest::Representation
+          command.request_object = cancel_operation_request_object
+          command.response_representation = Google::Apis::GenomicsV1::Empty::Representation
+          command.response_class = Google::Apis::GenomicsV1::Empty
+          command.params['name'] = name unless name.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -1602,11 +1602,11 @@ module Google
         # [GlobalAllianceApi.searchReferenceSets](https://github.com/ga4gh/schemas/blob/
         # v0.5.1/src/main/resources/avro/referencemethods.avdl#L71)
         # @param [Google::Apis::GenomicsV1::SearchReferenceSetsRequest] search_reference_sets_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1619,14 +1619,14 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def search_referenceset_reference_sets(search_reference_sets_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
+        def search_reference_sets(search_reference_sets_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:post, 'v1/referencesets/search', options)
           command.request_representation = Google::Apis::GenomicsV1::SearchReferenceSetsRequest::Representation
           command.request_object = search_reference_sets_request_object
           command.response_representation = Google::Apis::GenomicsV1::SearchReferenceSetsResponse::Representation
           command.response_class = Google::Apis::GenomicsV1::SearchReferenceSetsResponse
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
@@ -1639,11 +1639,11 @@ module Google
         # 1/src/main/resources/avro/referencemethods.avdl#L83).
         # @param [String] reference_set_id
         #   The ID of the reference set.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
@@ -1656,543 +1656,543 @@ module Google
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def get_referenceset(reference_set_id, fields: nil, quota_user: nil, options: nil, &block)
+        def get_reference_set(reference_set_id, quota_user: nil, fields: nil, options: nil, &block)
           command =  make_simple_command(:get, 'v1/referencesets/{referenceSetId}', options)
           command.response_representation = Google::Apis::GenomicsV1::ReferenceSet::Representation
           command.response_class = Google::Apis::GenomicsV1::ReferenceSet
           command.params['referenceSetId'] = reference_set_id unless reference_set_id.nil?
-          command.query['fields'] = fields unless fields.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Deletes a call set.
-        # For the definitions of call sets and other genomics resources, see
+        # Exports a read group set to a BAM file in Google Cloud Storage.
+        # For the definitions of read group sets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # @param [String] call_set_id
-        #   The ID of the call set to be deleted.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # Note that currently there may be some differences between exported BAM
+        # files and the original BAM file at the time of import. See
+        # ImportReadGroupSets
+        # for caveats.
+        # @param [String] read_group_set_id
+        #   Required. The ID of the read group set to export. The caller must have
+        #   READ access to this read group set.
+        # @param [Google::Apis::GenomicsV1::ExportReadGroupSetRequest] export_read_group_set_request_object
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::Empty] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::Operation] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::Empty]
+        # @return [Google::Apis::GenomicsV1::Operation]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def delete_callset(call_set_id, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:delete, 'v1/callsets/{callSetId}', options)
-          command.response_representation = Google::Apis::GenomicsV1::Empty::Representation
-          command.response_class = Google::Apis::GenomicsV1::Empty
-          command.params['callSetId'] = call_set_id unless call_set_id.nil?
-          command.query['fields'] = fields unless fields.nil?
+        def export_read_group_sets(read_group_set_id, export_read_group_set_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/readgroupsets/{readGroupSetId}:export', options)
+          command.request_representation = Google::Apis::GenomicsV1::ExportReadGroupSetRequest::Representation
+          command.request_object = export_read_group_set_request_object
+          command.response_representation = Google::Apis::GenomicsV1::Operation::Representation
+          command.response_class = Google::Apis::GenomicsV1::Operation
+          command.params['readGroupSetId'] = read_group_set_id unless read_group_set_id.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Gets a list of call sets matching the criteria.
-        # For the definitions of call sets and other genomics resources, see
+        # Searches for read group sets matching the criteria.
+        # For the definitions of read group sets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
         # Implements
-        # [GlobalAllianceApi.searchCallSets](https://github.com/ga4gh/schemas/blob/v0.5.
-        # 1/src/main/resources/avro/variantmethods.avdl#L178).
-        # @param [Google::Apis::GenomicsV1::SearchCallSetsRequest] search_call_sets_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # [GlobalAllianceApi.searchReadGroupSets](https://github.com/ga4gh/schemas/blob/
+        # v0.5.1/src/main/resources/avro/readmethods.avdl#L135).
+        # @param [Google::Apis::GenomicsV1::SearchReadGroupSetsRequest] search_read_group_sets_request_object
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::SearchCallSetsResponse] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::SearchReadGroupSetsResponse] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::SearchCallSetsResponse]
+        # @return [Google::Apis::GenomicsV1::SearchReadGroupSetsResponse]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def search_callset_call_sets(search_call_sets_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/callsets/search', options)
-          command.request_representation = Google::Apis::GenomicsV1::SearchCallSetsRequest::Representation
-          command.request_object = search_call_sets_request_object
-          command.response_representation = Google::Apis::GenomicsV1::SearchCallSetsResponse::Representation
-          command.response_class = Google::Apis::GenomicsV1::SearchCallSetsResponse
-          command.query['fields'] = fields unless fields.nil?
+        def search_read_group_sets(search_read_group_sets_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/readgroupsets/search', options)
+          command.request_representation = Google::Apis::GenomicsV1::SearchReadGroupSetsRequest::Representation
+          command.request_object = search_read_group_sets_request_object
+          command.response_representation = Google::Apis::GenomicsV1::SearchReadGroupSetsResponse::Representation
+          command.response_class = Google::Apis::GenomicsV1::SearchReadGroupSetsResponse
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Updates a call set.
-        # For the definitions of call sets and other genomics resources, see
+        # Gets a read group set by ID.
+        # For the definitions of read group sets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # This method supports patch semantics.
-        # @param [String] call_set_id
-        #   The ID of the call set to be updated.
-        # @param [Google::Apis::GenomicsV1::CallSet] call_set_object
-        # @param [String] update_mask
-        #   An optional mask specifying which fields to update. At this time, the only
-        #   mutable field is name. The only
-        #   acceptable value is "name". If unspecified, all mutable fields will be
-        #   updated.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # @param [String] read_group_set_id
+        #   The ID of the read group set.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::CallSet] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::ReadGroupSet] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::CallSet]
+        # @return [Google::Apis::GenomicsV1::ReadGroupSet]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def patch_callset(call_set_id, call_set_object = nil, update_mask: nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:patch, 'v1/callsets/{callSetId}', options)
-          command.request_representation = Google::Apis::GenomicsV1::CallSet::Representation
-          command.request_object = call_set_object
-          command.response_representation = Google::Apis::GenomicsV1::CallSet::Representation
-          command.response_class = Google::Apis::GenomicsV1::CallSet
-          command.params['callSetId'] = call_set_id unless call_set_id.nil?
-          command.query['updateMask'] = update_mask unless update_mask.nil?
-          command.query['fields'] = fields unless fields.nil?
+        def get_read_group_set(read_group_set_id, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:get, 'v1/readgroupsets/{readGroupSetId}', options)
+          command.response_representation = Google::Apis::GenomicsV1::ReadGroupSet::Representation
+          command.response_class = Google::Apis::GenomicsV1::ReadGroupSet
+          command.params['readGroupSetId'] = read_group_set_id unless read_group_set_id.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Gets a call set by ID.
-        # For the definitions of call sets and other genomics resources, see
+        # Updates a read group set.
+        # For the definitions of read group sets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # @param [String] call_set_id
-        #   The ID of the call set.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # This method supports patch semantics.
+        # @param [String] read_group_set_id
+        #   The ID of the read group set to be updated. The caller must have WRITE
+        #   permissions to the dataset associated with this read group set.
+        # @param [Google::Apis::GenomicsV1::ReadGroupSet] read_group_set_object
+        # @param [String] update_mask
+        #   An optional mask specifying which fields to update. Supported fields:
+        #   * name.
+        #   * referenceSetId.
+        #   Leaving `updateMask` unset is equivalent to specifying all mutable
+        #   fields.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::CallSet] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::ReadGroupSet] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::CallSet]
+        # @return [Google::Apis::GenomicsV1::ReadGroupSet]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def get_callset(call_set_id, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:get, 'v1/callsets/{callSetId}', options)
-          command.response_representation = Google::Apis::GenomicsV1::CallSet::Representation
-          command.response_class = Google::Apis::GenomicsV1::CallSet
-          command.params['callSetId'] = call_set_id unless call_set_id.nil?
-          command.query['fields'] = fields unless fields.nil?
+        def patch_read_group_set(read_group_set_id, read_group_set_object = nil, update_mask: nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:patch, 'v1/readgroupsets/{readGroupSetId}', options)
+          command.request_representation = Google::Apis::GenomicsV1::ReadGroupSet::Representation
+          command.request_object = read_group_set_object
+          command.response_representation = Google::Apis::GenomicsV1::ReadGroupSet::Representation
+          command.response_class = Google::Apis::GenomicsV1::ReadGroupSet
+          command.params['readGroupSetId'] = read_group_set_id unless read_group_set_id.nil?
+          command.query['updateMask'] = update_mask unless update_mask.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Creates a new call set.
-        # For the definitions of call sets and other genomics resources, see
+        # Creates read group sets by asynchronously importing the provided
+        # information.
+        # For the definitions of read group sets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # @param [Google::Apis::GenomicsV1::CallSet] call_set_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # The caller must have WRITE permissions to the dataset.
+        # ## Notes on [BAM](https://samtools.github.io/hts-specs/SAMv1.pdf) import
+        # - Tags will be converted to strings - tag types are not preserved
+        # - Comments (`@CO`) in the input file header will not be preserved
+        # - Original header order of references (`@SQ`) will not be preserved
+        # - Any reverse stranded unmapped reads will be reverse complemented, and
+        # their qualities (also the "BQ" and "OQ" tags, if any) will be reversed
+        # - Unmapped reads will be stripped of positional information (reference name
+        # and position)
+        # @param [Google::Apis::GenomicsV1::ImportReadGroupSetsRequest] import_read_group_sets_request_object
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::CallSet] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::Operation] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::CallSet]
+        # @return [Google::Apis::GenomicsV1::Operation]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def create_callset(call_set_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/callsets', options)
-          command.request_representation = Google::Apis::GenomicsV1::CallSet::Representation
-          command.request_object = call_set_object
-          command.response_representation = Google::Apis::GenomicsV1::CallSet::Representation
-          command.response_class = Google::Apis::GenomicsV1::CallSet
-          command.query['fields'] = fields unless fields.nil?
+        def import_read_group_sets(import_read_group_sets_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/readgroupsets:import', options)
+          command.request_representation = Google::Apis::GenomicsV1::ImportReadGroupSetsRequest::Representation
+          command.request_object = import_read_group_sets_request_object
+          command.response_representation = Google::Apis::GenomicsV1::Operation::Representation
+          command.response_class = Google::Apis::GenomicsV1::Operation
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Gets a list of reads for one or more read group sets.
+        # Deletes a read group set.
         # For the definitions of read group sets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # Reads search operates over a genomic coordinate space of reference sequence
-        # & position defined over the reference sequences to which the requested
-        # read group sets are aligned.
-        # If a target positional range is specified, search returns all reads whose
-        # alignment to the reference genome overlap the range. A query which
-        # specifies only read group set IDs yields all reads in those read group
-        # sets, including unmapped reads.
-        # All reads returned (including reads on subsequent pages) are ordered by
-        # genomic coordinate (by reference sequence, then position). Reads with
-        # equivalent genomic coordinates are returned in an unspecified order. This
-        # order is consistent, such that two queries for the same content (regardless
-        # of page size) yield reads in the same order across their respective streams
-        # of paginated responses.
-        # Implements
-        # [GlobalAllianceApi.searchReads](https://github.com/ga4gh/schemas/blob/v0.5.1/
-        # src/main/resources/avro/readmethods.avdl#L85).
-        # @param [Google::Apis::GenomicsV1::SearchReadsRequest] search_reads_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # @param [String] read_group_set_id
+        #   The ID of the read group set to be deleted. The caller must have WRITE
+        #   permissions to the dataset associated with this read group set.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::SearchReadsResponse] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::Empty] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::SearchReadsResponse]
+        # @return [Google::Apis::GenomicsV1::Empty]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def search_reads(search_reads_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/reads/search', options)
-          command.request_representation = Google::Apis::GenomicsV1::SearchReadsRequest::Representation
-          command.request_object = search_reads_request_object
-          command.response_representation = Google::Apis::GenomicsV1::SearchReadsResponse::Representation
-          command.response_class = Google::Apis::GenomicsV1::SearchReadsResponse
-          command.query['fields'] = fields unless fields.nil?
+        def delete_read_group_set(read_group_set_id, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:delete, 'v1/readgroupsets/{readGroupSetId}', options)
+          command.response_representation = Google::Apis::GenomicsV1::Empty::Representation
+          command.response_class = Google::Apis::GenomicsV1::Empty
+          command.params['readGroupSetId'] = read_group_set_id unless read_group_set_id.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Exports a read group set to a BAM file in Google Cloud Storage.
+        # Lists fixed width coverage buckets for a read group set, each of which
+        # correspond to a range of a reference sequence. Each bucket summarizes
+        # coverage information across its corresponding genomic range.
         # For the definitions of read group sets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # Note that currently there may be some differences between exported BAM
-        # files and the original BAM file at the time of import. See
-        # ImportReadGroupSets
-        # for caveats.
+        # Coverage is defined as the number of reads which are aligned to a given
+        # base in the reference sequence. Coverage buckets are available at several
+        # precomputed bucket widths, enabling retrieval of various coverage 'zoom
+        # levels'. The caller must have READ permissions for the target read group
+        # set.
         # @param [String] read_group_set_id
-        #   Required. The ID of the read group set to export. The caller must have
-        #   READ access to this read group set.
-        # @param [Google::Apis::GenomicsV1::ExportReadGroupSetRequest] export_read_group_set_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        #   Required. The ID of the read group set over which coverage is requested.
+        # @param [String] page_token
+        #   The continuation token, which is used to page through large result sets.
+        #   To get the next page of results, set this parameter to the value of
+        #   `nextPageToken` from the previous response.
+        # @param [Fixnum] page_size
+        #   The maximum number of results to return in a single page. If unspecified,
+        #   defaults to 1024. The maximum value is 2048.
+        # @param [Fixnum] start
+        #   The start position of the range on the reference, 0-based inclusive. If
+        #   specified, `referenceName` must also be specified. Defaults to 0.
+        # @param [Fixnum] target_bucket_width
+        #   The desired width of each reported coverage bucket in base pairs. This
+        #   will be rounded down to the nearest precomputed bucket width; the value
+        #   of which is returned as `bucketWidth` in the response. Defaults
+        #   to infinity (each bucket spans an entire reference sequence) or the length
+        #   of the target range, if specified. The smallest precomputed
+        #   `bucketWidth` is currently 2048 base pairs; this is subject to
+        #   change.
+        # @param [String] reference_name
+        #   The name of the reference to query, within the reference set associated
+        #   with this query. Optional.
+        # @param [Fixnum] end_
+        #   The end position of the range on the reference, 0-based exclusive. If
+        #   specified, `referenceName` must also be specified. If unset or 0, defaults
+        #   to the length of the reference.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::Operation] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::ListCoverageBucketsResponse] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::Operation]
+        # @return [Google::Apis::GenomicsV1::ListCoverageBucketsResponse]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def export_readgroupset_read_group_set(read_group_set_id, export_read_group_set_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/readgroupsets/{readGroupSetId}:export', options)
-          command.request_representation = Google::Apis::GenomicsV1::ExportReadGroupSetRequest::Representation
-          command.request_object = export_read_group_set_request_object
-          command.response_representation = Google::Apis::GenomicsV1::Operation::Representation
-          command.response_class = Google::Apis::GenomicsV1::Operation
+        def list_coverage_buckets(read_group_set_id, page_token: nil, page_size: nil, start: nil, target_bucket_width: nil, reference_name: nil, end_: nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:get, 'v1/readgroupsets/{readGroupSetId}/coveragebuckets', options)
+          command.response_representation = Google::Apis::GenomicsV1::ListCoverageBucketsResponse::Representation
+          command.response_class = Google::Apis::GenomicsV1::ListCoverageBucketsResponse
           command.params['readGroupSetId'] = read_group_set_id unless read_group_set_id.nil?
-          command.query['fields'] = fields unless fields.nil?
+          command.query['pageToken'] = page_token unless page_token.nil?
+          command.query['pageSize'] = page_size unless page_size.nil?
+          command.query['start'] = start unless start.nil?
+          command.query['targetBucketWidth'] = target_bucket_width unless target_bucket_width.nil?
+          command.query['referenceName'] = reference_name unless reference_name.nil?
+          command.query['end'] = end_ unless end_.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Searches for read group sets matching the criteria.
+        # Gets a list of reads for one or more read group sets.
         # For the definitions of read group sets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
+        # Reads search operates over a genomic coordinate space of reference sequence
+        # & position defined over the reference sequences to which the requested
+        # read group sets are aligned.
+        # If a target positional range is specified, search returns all reads whose
+        # alignment to the reference genome overlap the range. A query which
+        # specifies only read group set IDs yields all reads in those read group
+        # sets, including unmapped reads.
+        # All reads returned (including reads on subsequent pages) are ordered by
+        # genomic coordinate (by reference sequence, then position). Reads with
+        # equivalent genomic coordinates are returned in an unspecified order. This
+        # order is consistent, such that two queries for the same content (regardless
+        # of page size) yield reads in the same order across their respective streams
+        # of paginated responses.
         # Implements
-        # [GlobalAllianceApi.searchReadGroupSets](https://github.com/ga4gh/schemas/blob/
-        # v0.5.1/src/main/resources/avro/readmethods.avdl#L135).
-        # @param [Google::Apis::GenomicsV1::SearchReadGroupSetsRequest] search_read_group_sets_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # [GlobalAllianceApi.searchReads](https://github.com/ga4gh/schemas/blob/v0.5.1/
+        # src/main/resources/avro/readmethods.avdl#L85).
+        # @param [Google::Apis::GenomicsV1::SearchReadsRequest] search_reads_request_object
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::SearchReadGroupSetsResponse] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::SearchReadsResponse] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::SearchReadGroupSetsResponse]
+        # @return [Google::Apis::GenomicsV1::SearchReadsResponse]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def search_readgroupset_read_group_sets(search_read_group_sets_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/readgroupsets/search', options)
-          command.request_representation = Google::Apis::GenomicsV1::SearchReadGroupSetsRequest::Representation
-          command.request_object = search_read_group_sets_request_object
-          command.response_representation = Google::Apis::GenomicsV1::SearchReadGroupSetsResponse::Representation
-          command.response_class = Google::Apis::GenomicsV1::SearchReadGroupSetsResponse
-          command.query['fields'] = fields unless fields.nil?
+        def search_reads(search_reads_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/reads/search', options)
+          command.request_representation = Google::Apis::GenomicsV1::SearchReadsRequest::Representation
+          command.request_object = search_reads_request_object
+          command.response_representation = Google::Apis::GenomicsV1::SearchReadsResponse::Representation
+          command.response_class = Google::Apis::GenomicsV1::SearchReadsResponse
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Gets a read group set by ID.
-        # For the definitions of read group sets and other genomics resources, see
+        # Updates a call set.
+        # For the definitions of call sets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # @param [String] read_group_set_id
-        #   The ID of the read group set.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # This method supports patch semantics.
+        # @param [String] call_set_id
+        #   The ID of the call set to be updated.
+        # @param [Google::Apis::GenomicsV1::CallSet] call_set_object
+        # @param [String] update_mask
+        #   An optional mask specifying which fields to update. At this time, the only
+        #   mutable field is name. The only
+        #   acceptable value is "name". If unspecified, all mutable fields will be
+        #   updated.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::ReadGroupSet] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::CallSet] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::ReadGroupSet]
+        # @return [Google::Apis::GenomicsV1::CallSet]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def get_readgroupset(read_group_set_id, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:get, 'v1/readgroupsets/{readGroupSetId}', options)
-          command.response_representation = Google::Apis::GenomicsV1::ReadGroupSet::Representation
-          command.response_class = Google::Apis::GenomicsV1::ReadGroupSet
-          command.params['readGroupSetId'] = read_group_set_id unless read_group_set_id.nil?
-          command.query['fields'] = fields unless fields.nil?
+        def patch_call_set(call_set_id, call_set_object = nil, update_mask: nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:patch, 'v1/callsets/{callSetId}', options)
+          command.request_representation = Google::Apis::GenomicsV1::CallSet::Representation
+          command.request_object = call_set_object
+          command.response_representation = Google::Apis::GenomicsV1::CallSet::Representation
+          command.response_class = Google::Apis::GenomicsV1::CallSet
+          command.params['callSetId'] = call_set_id unless call_set_id.nil?
+          command.query['updateMask'] = update_mask unless update_mask.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Updates a read group set.
-        # For the definitions of read group sets and other genomics resources, see
+        # Gets a call set by ID.
+        # For the definitions of call sets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # This method supports patch semantics.
-        # @param [String] read_group_set_id
-        #   The ID of the read group set to be updated. The caller must have WRITE
-        #   permissions to the dataset associated with this read group set.
-        # @param [Google::Apis::GenomicsV1::ReadGroupSet] read_group_set_object
-        # @param [String] update_mask
-        #   An optional mask specifying which fields to update. Supported fields:
-        #   * name.
-        #   * referenceSetId.
-        #   Leaving `updateMask` unset is equivalent to specifying all mutable
-        #   fields.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # @param [String] call_set_id
+        #   The ID of the call set.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::ReadGroupSet] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::CallSet] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::ReadGroupSet]
+        # @return [Google::Apis::GenomicsV1::CallSet]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def patch_readgroupset(read_group_set_id, read_group_set_object = nil, update_mask: nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:patch, 'v1/readgroupsets/{readGroupSetId}', options)
-          command.request_representation = Google::Apis::GenomicsV1::ReadGroupSet::Representation
-          command.request_object = read_group_set_object
-          command.response_representation = Google::Apis::GenomicsV1::ReadGroupSet::Representation
-          command.response_class = Google::Apis::GenomicsV1::ReadGroupSet
-          command.params['readGroupSetId'] = read_group_set_id unless read_group_set_id.nil?
-          command.query['updateMask'] = update_mask unless update_mask.nil?
-          command.query['fields'] = fields unless fields.nil?
+        def get_call_set(call_set_id, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:get, 'v1/callsets/{callSetId}', options)
+          command.response_representation = Google::Apis::GenomicsV1::CallSet::Representation
+          command.response_class = Google::Apis::GenomicsV1::CallSet
+          command.params['callSetId'] = call_set_id unless call_set_id.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Deletes a read group set.
-        # For the definitions of read group sets and other genomics resources, see
+        # Creates a new call set.
+        # For the definitions of call sets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # @param [String] read_group_set_id
-        #   The ID of the read group set to be deleted. The caller must have WRITE
-        #   permissions to the dataset associated with this read group set.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # @param [Google::Apis::GenomicsV1::CallSet] call_set_object
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::Empty] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::CallSet] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::Empty]
+        # @return [Google::Apis::GenomicsV1::CallSet]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def delete_readgroupset(read_group_set_id, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:delete, 'v1/readgroupsets/{readGroupSetId}', options)
-          command.response_representation = Google::Apis::GenomicsV1::Empty::Representation
-          command.response_class = Google::Apis::GenomicsV1::Empty
-          command.params['readGroupSetId'] = read_group_set_id unless read_group_set_id.nil?
-          command.query['fields'] = fields unless fields.nil?
+        def create_call_set(call_set_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/callsets', options)
+          command.request_representation = Google::Apis::GenomicsV1::CallSet::Representation
+          command.request_object = call_set_object
+          command.response_representation = Google::Apis::GenomicsV1::CallSet::Representation
+          command.response_class = Google::Apis::GenomicsV1::CallSet
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Creates read group sets by asynchronously importing the provided
-        # information.
-        # For the definitions of read group sets and other genomics resources, see
+        # Deletes a call set.
+        # For the definitions of call sets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # The caller must have WRITE permissions to the dataset.
-        # ## Notes on [BAM](https://samtools.github.io/hts-specs/SAMv1.pdf) import
-        # - Tags will be converted to strings - tag types are not preserved
-        # - Comments (`@CO`) in the input file header will not be preserved
-        # - Original header order of references (`@SQ`) will not be preserved
-        # - Any reverse stranded unmapped reads will be reverse complemented, and
-        # their qualities (also the "BQ" and "OQ" tags, if any) will be reversed
-        # - Unmapped reads will be stripped of positional information (reference name
-        # and position)
-        # @param [Google::Apis::GenomicsV1::ImportReadGroupSetsRequest] import_read_group_sets_request_object
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # @param [String] call_set_id
+        #   The ID of the call set to be deleted.
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::Operation] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::Empty] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::Operation]
+        # @return [Google::Apis::GenomicsV1::Empty]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def import_readgroupset_read_group_sets(import_read_group_sets_request_object = nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:post, 'v1/readgroupsets:import', options)
-          command.request_representation = Google::Apis::GenomicsV1::ImportReadGroupSetsRequest::Representation
-          command.request_object = import_read_group_sets_request_object
-          command.response_representation = Google::Apis::GenomicsV1::Operation::Representation
-          command.response_class = Google::Apis::GenomicsV1::Operation
-          command.query['fields'] = fields unless fields.nil?
+        def delete_call_set(call_set_id, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:delete, 'v1/callsets/{callSetId}', options)
+          command.response_representation = Google::Apis::GenomicsV1::Empty::Representation
+          command.response_class = Google::Apis::GenomicsV1::Empty
+          command.params['callSetId'] = call_set_id unless call_set_id.nil?
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end
         
-        # Lists fixed width coverage buckets for a read group set, each of which
-        # correspond to a range of a reference sequence. Each bucket summarizes
-        # coverage information across its corresponding genomic range.
-        # For the definitions of read group sets and other genomics resources, see
+        # Gets a list of call sets matching the criteria.
+        # For the definitions of call sets and other genomics resources, see
         # [Fundamentals of Google
         # Genomics](https://cloud.google.com/genomics/fundamentals-of-google-genomics)
-        # Coverage is defined as the number of reads which are aligned to a given
-        # base in the reference sequence. Coverage buckets are available at several
-        # precomputed bucket widths, enabling retrieval of various coverage 'zoom
-        # levels'. The caller must have READ permissions for the target read group
-        # set.
-        # @param [String] read_group_set_id
-        #   Required. The ID of the read group set over which coverage is requested.
-        # @param [String] reference_name
-        #   The name of the reference to query, within the reference set associated
-        #   with this query. Optional.
-        # @param [Fixnum] end_
-        #   The end position of the range on the reference, 0-based exclusive. If
-        #   specified, `referenceName` must also be specified. If unset or 0, defaults
-        #   to the length of the reference.
-        # @param [String] page_token
-        #   The continuation token, which is used to page through large result sets.
-        #   To get the next page of results, set this parameter to the value of
-        #   `nextPageToken` from the previous response.
-        # @param [Fixnum] page_size
-        #   The maximum number of results to return in a single page. If unspecified,
-        #   defaults to 1024. The maximum value is 2048.
-        # @param [Fixnum] start
-        #   The start position of the range on the reference, 0-based inclusive. If
-        #   specified, `referenceName` must also be specified. Defaults to 0.
-        # @param [Fixnum] target_bucket_width
-        #   The desired width of each reported coverage bucket in base pairs. This
-        #   will be rounded down to the nearest precomputed bucket width; the value
-        #   of which is returned as `bucketWidth` in the response. Defaults
-        #   to infinity (each bucket spans an entire reference sequence) or the length
-        #   of the target range, if specified. The smallest precomputed
-        #   `bucketWidth` is currently 2048 base pairs; this is subject to
-        #   change.
-        # @param [String] fields
-        #   Selector specifying which fields to include in a partial response.
+        # Implements
+        # [GlobalAllianceApi.searchCallSets](https://github.com/ga4gh/schemas/blob/v0.5.
+        # 1/src/main/resources/avro/variantmethods.avdl#L178).
+        # @param [Google::Apis::GenomicsV1::SearchCallSetsRequest] search_call_sets_request_object
         # @param [String] quota_user
         #   Available to use for quota purposes for server-side applications. Can be any
         #   arbitrary string assigned to a user, but should not exceed 40 characters.
+        # @param [String] fields
+        #   Selector specifying which fields to include in a partial response.
         # @param [Google::Apis::RequestOptions] options
         #   Request-specific options
         #
         # @yield [result, err] Result & error if block supplied
-        # @yieldparam result [Google::Apis::GenomicsV1::ListCoverageBucketsResponse] parsed result object
+        # @yieldparam result [Google::Apis::GenomicsV1::SearchCallSetsResponse] parsed result object
         # @yieldparam err [StandardError] error object if request failed
         #
-        # @return [Google::Apis::GenomicsV1::ListCoverageBucketsResponse]
+        # @return [Google::Apis::GenomicsV1::SearchCallSetsResponse]
         #
         # @raise [Google::Apis::ServerError] An error occurred on the server and the request can be retried
         # @raise [Google::Apis::ClientError] The request is invalid and should not be retried without modification
         # @raise [Google::Apis::AuthorizationError] Authorization is required
-        def list_readgroupset_coveragebuckets(read_group_set_id, reference_name: nil, end_: nil, page_token: nil, page_size: nil, start: nil, target_bucket_width: nil, fields: nil, quota_user: nil, options: nil, &block)
-          command =  make_simple_command(:get, 'v1/readgroupsets/{readGroupSetId}/coveragebuckets', options)
-          command.response_representation = Google::Apis::GenomicsV1::ListCoverageBucketsResponse::Representation
-          command.response_class = Google::Apis::GenomicsV1::ListCoverageBucketsResponse
-          command.params['readGroupSetId'] = read_group_set_id unless read_group_set_id.nil?
-          command.query['referenceName'] = reference_name unless reference_name.nil?
-          command.query['end'] = end_ unless end_.nil?
-          command.query['pageToken'] = page_token unless page_token.nil?
-          command.query['pageSize'] = page_size unless page_size.nil?
-          command.query['start'] = start unless start.nil?
-          command.query['targetBucketWidth'] = target_bucket_width unless target_bucket_width.nil?
-          command.query['fields'] = fields unless fields.nil?
+        def search_call_sets(search_call_sets_request_object = nil, quota_user: nil, fields: nil, options: nil, &block)
+          command =  make_simple_command(:post, 'v1/callsets/search', options)
+          command.request_representation = Google::Apis::GenomicsV1::SearchCallSetsRequest::Representation
+          command.request_object = search_call_sets_request_object
+          command.response_representation = Google::Apis::GenomicsV1::SearchCallSetsResponse::Representation
+          command.response_class = Google::Apis::GenomicsV1::SearchCallSetsResponse
           command.query['quotaUser'] = quota_user unless quota_user.nil?
+          command.query['fields'] = fields unless fields.nil?
           execute_or_queue_command(command, &block)
         end