bives 0.1
Sign up to get free protection for your applications and to get access to all the features.
- checksums.yaml +15 -0
- data/.gitignore +18 -0
- data/.ruby-gemset +1 -0
- data/.ruby-version +1 -0
- data/Gemfile +7 -0
- data/LICENSE.txt +22 -0
- data/README.md +29 -0
- data/Rakefile +1 -0
- data/bives.gemspec +36 -0
- data/lib/bives/version.rb +3 -0
- data/lib/bives.rb +40 -0
- data/lib/jars/BiVeS-1.1.2-SNAPSHOT-fat.jar +0 -0
- data/test/bives_test.rb +21 -0
- data/test/models/potato1.xml +1819 -0
- data/test/models/potato2.xml +1764 -0
- metadata +90 -0
@@ -0,0 +1,1764 @@
|
|
1
|
+
<?xml version="1.0" encoding="UTF-8"?>
|
2
|
+
<!-- Created by JWS2SBML on 2008/05/26 09:12:13-->
|
3
|
+
<sbml xmlns="http://www.sbml.org/sbml/level2" level="2" version="1">
|
4
|
+
<model name="assmus">
|
5
|
+
<listOfCompartments>
|
6
|
+
<compartment id="compartment" name="compartment" size="1"/>
|
7
|
+
</listOfCompartments>
|
8
|
+
<listOfSpecies>
|
9
|
+
<species id="G1Pam" name="G1Pam" compartment="compartment" initialConcentration="30"/>
|
10
|
+
<species id="ATPam" name="ATPam" compartment="compartment" initialConcentration="150"/>
|
11
|
+
<species id="ADPGam" name="ADPGam" compartment="compartment" initialConcentration="100"/>
|
12
|
+
<species id="PPam" name="PPam" compartment="compartment" initialConcentration="5"/>
|
13
|
+
<species id="PGA3am" name="PGA3am" compartment="compartment" initialConcentration="160"/>
|
14
|
+
<species id="Pam" name="Pam" compartment="compartment" initialConcentration="2000"/>
|
15
|
+
<species id="xstarch" name="xstarch" compartment="compartment" initialConcentration="1000000" boundaryCondition="true" constant="true"/>
|
16
|
+
<species id="ADPam" name="ADPam" compartment="compartment" initialConcentration="100"/>
|
17
|
+
<species id="Glucoseam" name="Glucoseam" compartment="compartment" initialConcentration="3000"/>
|
18
|
+
<species id="Glucosecyt" name="Glucosecyt" compartment="compartment" initialConcentration="150"/>
|
19
|
+
<species id="G6Pam" name="G6Pam" compartment="compartment" initialConcentration="550"/>
|
20
|
+
<species id="Pcyt" name="Pcyt" compartment="compartment" initialConcentration="2000"/>
|
21
|
+
<species id="G6Pcyt" name="G6Pcyt" compartment="compartment" initialConcentration="500"/>
|
22
|
+
<species id="G1Pcyt" name="G1Pcyt" compartment="compartment" initialConcentration="30"/>
|
23
|
+
<species id="F6Pcyt" name="F6Pcyt" compartment="compartment" initialConcentration="160"/>
|
24
|
+
<species id="F16BPcyt" name="F16BPcyt" compartment="compartment" initialConcentration="1"/>
|
25
|
+
<species id="PEPcyt" name="PEPcyt" compartment="compartment" initialConcentration="10"/>
|
26
|
+
<species id="ATPcyt" name="ATPcyt" compartment="compartment" initialConcentration="200"/>
|
27
|
+
<species id="ADPcyt" name="ADPcyt" compartment="compartment" initialConcentration="180"/>
|
28
|
+
<species id="PPcyt" name="PPcyt" compartment="compartment" initialConcentration="1"/>
|
29
|
+
<species id="GAPcyt" name="GAPcyt" compartment="compartment" initialConcentration="1"/>
|
30
|
+
<species id="DHAPcyt" name="DHAPcyt" compartment="compartment" initialConcentration="5"/>
|
31
|
+
<species id="PGA3cyt" name="PGA3cyt" compartment="compartment" initialConcentration="150"/>
|
32
|
+
<species id="PGA2cyt" name="PGA2cyt" compartment="compartment" initialConcentration="20"/>
|
33
|
+
<species id="xpyruvate" name="xpyruvate" compartment="compartment" initialConcentration="10" boundaryCondition="true" constant="true"/>
|
34
|
+
<species id="UTPcyt" name="UTPcyt" compartment="compartment" initialConcentration="20"/>
|
35
|
+
<species id="UDPGcyt" name="UDPGcyt" compartment="compartment" initialConcentration="870"/>
|
36
|
+
<species id="Sucrose" name="Sucrose" compartment="compartment" initialConcentration="88000"/>
|
37
|
+
<species id="UDPcyt" name="UDPcyt" compartment="compartment" initialConcentration="10"/>
|
38
|
+
<species id="Fructose" name="Fructose" compartment="compartment" initialConcentration="20"/>
|
39
|
+
<species id="xsucrose" name="xsucrose" compartment="compartment" initialConcentration="90000" boundaryCondition="true" constant="true"/>
|
40
|
+
</listOfSpecies>
|
41
|
+
<listOfParameters>
|
42
|
+
<parameter id="VmaxAGPase" name="VmaxAGPase" value="312"/>
|
43
|
+
<parameter id="KmG1PAGPase" name="KmG1PAGPase" value="100"/>
|
44
|
+
<parameter id="KmATPAGPase" name="KmATPAGPase" value="180"/>
|
45
|
+
<parameter id="KmADPGAGPase" name="KmADPGAGPase" value="280"/>
|
46
|
+
<parameter id="KmPPAGPase" name="KmPPAGPase" value="260"/>
|
47
|
+
<parameter id="KiPAGPase" name="KiPAGPase" value="160"/>
|
48
|
+
<parameter id="KaPGA3AGPase" name="KaPGA3AGPase" value="10"/>
|
49
|
+
<parameter id="VmaxStSynth" name="VmaxStSynth" value="171"/>
|
50
|
+
<parameter id="KmADPGStSynth" name="KmADPGStSynth" value="150"/>
|
51
|
+
<parameter id="VmaxpPPase" name="VmaxpPPase" value="500"/>
|
52
|
+
<parameter id="KeqpPPase" name="KeqpPPase" value="750000"/>
|
53
|
+
<parameter id="VforwardStPase" name="VforwardStPase" value="200"/>
|
54
|
+
<parameter id="KmPStPase" name="KmPStPase" value="6200"/>
|
55
|
+
<parameter id="KmG1PStPase" name="KmG1PStPase" value="2600"/>
|
56
|
+
<parameter id="KeqStPase" name="KeqStPase" value="0.18"/>
|
57
|
+
<parameter id="Vmaxdegr" name="Vmaxdegr" value="114"/>
|
58
|
+
<parameter id="KiGlucosedegr" name="KiGlucosedegr" value="100"/>
|
59
|
+
<parameter id="VGexp" name="VGexp" value="1"/>
|
60
|
+
<parameter id="kforwardGexp" name="kforwardGexp" value="0.001"/>
|
61
|
+
<parameter id="kbackwardGexp" name="kbackwardGexp" value="0.001"/>
|
62
|
+
<parameter id="VG6Pexp" name="VG6Pexp" value="1"/>
|
63
|
+
<parameter id="kforwardG6Pexp" name="kforwardG6Pexp" value="0.01"/>
|
64
|
+
<parameter id="kbackwardG6Pexp" name="kbackwardG6Pexp" value="0.01"/>
|
65
|
+
<parameter id="VmaxpPGM" name="VmaxpPGM" value="1542"/>
|
66
|
+
<parameter id="KeqpPGM" name="KeqpPGM" value="17"/>
|
67
|
+
<parameter id="VmaxcPGM" name="VmaxcPGM" value="1842"/>
|
68
|
+
<parameter id="KeqcPGM" name="KeqcPGM" value="17"/>
|
69
|
+
<parameter id="VmaxPGI" name="VmaxPGI" value="1086"/>
|
70
|
+
<parameter id="KmG6PPGI" name="KmG6PPGI" value="270"/>
|
71
|
+
<parameter id="KmF6PPGI" name="KmF6PPGI" value="150"/>
|
72
|
+
<parameter id="KeqPGI" name="KeqPGI" value="0.25"/>
|
73
|
+
<parameter id="KiPEPPGI" name="KiPEPPGI" value="1100"/>
|
74
|
+
<parameter id="KiF16BPPGI" name="KiF16BPPGI" value="7500"/>
|
75
|
+
<parameter id="VmaxPFK" name="VmaxPFK" value="135"/>
|
76
|
+
<parameter id="KmF6PPFK" name="KmF6PPFK" value="290"/>
|
77
|
+
<parameter id="KiPEPPFK" name="KiPEPPFK" value="18"/>
|
78
|
+
<parameter id="nPFK" name="nPFK" value="2"/>
|
79
|
+
<parameter id="LPFK" name="LPFK" value="1"/>
|
80
|
+
<parameter id="VmaxPFP" name="VmaxPFP" value="1266"/>
|
81
|
+
<parameter id="KmF6PPFP" name="KmF6PPFP" value="500"/>
|
82
|
+
<parameter id="KmPPPFP" name="KmPPPFP" value="25"/>
|
83
|
+
<parameter id="KmF16BPPFP" name="KmF16BPPFP" value="10"/>
|
84
|
+
<parameter id="KmPPFP" name="KmPPFP" value="10"/>
|
85
|
+
<parameter id="KeqPFP" name="KeqPFP" value="3.3"/>
|
86
|
+
<parameter id="Vmaxald" name="Vmaxald" value="430"/>
|
87
|
+
<parameter id="Keqald" name="Keqald" value="81"/>
|
88
|
+
<parameter id="KmF16BPald" name="KmF16BPald" value="6"/>
|
89
|
+
<parameter id="KmGAPald" name="KmGAPald" value="100"/>
|
90
|
+
<parameter id="KmDHAPald" name="KmDHAPald" value="100"/>
|
91
|
+
<parameter id="KiGAPald" name="KiGAPald" value="1000"/>
|
92
|
+
<parameter id="VmaxTPI" name="VmaxTPI" value="4438"/>
|
93
|
+
<parameter id="KeqTPI" name="KeqTPI" value="0.0455"/>
|
94
|
+
<parameter id="KmGAPTPI" name="KmGAPTPI" value="440"/>
|
95
|
+
<parameter id="KmDHAPTPI" name="KmDHAPTPI" value="880"/>
|
96
|
+
<parameter id="VmaxGAPDH" name="VmaxGAPDH" value="301"/>
|
97
|
+
<parameter id="KeqGAPDH" name="KeqGAPDH" value="1.724"/>
|
98
|
+
<parameter id="VPGA3imp" name="VPGA3imp" value="1"/>
|
99
|
+
<parameter id="kforwardPGA3imp" name="kforwardPGA3imp" value="0.01"/>
|
100
|
+
<parameter id="kbackwardPGA3imp" name="kbackwardPGA3imp" value="0.01"/>
|
101
|
+
<parameter id="VmaxPGlyM" name="VmaxPGlyM" value="541"/>
|
102
|
+
<parameter id="KeqPGlyM" name="KeqPGlyM" value="0.16"/>
|
103
|
+
<parameter id="KmPGA3PGlyM" name="KmPGA3PGlyM" value="330"/>
|
104
|
+
<parameter id="KmPGA2PGlyM" name="KmPGA2PGlyM" value="60"/>
|
105
|
+
<parameter id="Vmaxeno" name="Vmaxeno" value="448"/>
|
106
|
+
<parameter id="Keqeno" name="Keqeno" value="6.3"/>
|
107
|
+
<parameter id="KmPGA2eno" name="KmPGA2eno" value="150"/>
|
108
|
+
<parameter id="KmPEPeno" name="KmPEPeno" value="150"/>
|
109
|
+
<parameter id="VmaxPK" name="VmaxPK" value="127"/>
|
110
|
+
<parameter id="KmPEPPK" name="KmPEPPK" value="20"/>
|
111
|
+
<parameter id="KmADPPK" name="KmADPPK" value="20"/>
|
112
|
+
<parameter id="KmpyruvatePK" name="KmpyruvatePK" value="1000"/>
|
113
|
+
<parameter id="KmATPPK" name="KmATPPK" value="86"/>
|
114
|
+
<parameter id="VforwardUGPase" name="VforwardUGPase" value="8100"/>
|
115
|
+
<parameter id="KmG1PUGPase" name="KmG1PUGPase" value="80"/>
|
116
|
+
<parameter id="KmUTPUGPase" name="KmUTPUGPase" value="120"/>
|
117
|
+
<parameter id="KmUDPGUGPase" name="KmUDPGUGPase" value="140"/>
|
118
|
+
<parameter id="KmPPUGPase" name="KmPPUGPase" value="130"/>
|
119
|
+
<parameter id="KeqUGPase" name="KeqUGPase" value="0.15"/>
|
120
|
+
<parameter id="VmaxSPS" name="VmaxSPS" value="1000"/>
|
121
|
+
<parameter id="KmF6PSPS" name="KmF6PSPS" value="5000"/>
|
122
|
+
<parameter id="KmUDPGSPS" name="KmUDPGSPS" value="3000"/>
|
123
|
+
<parameter id="KiUDPSPS" name="KiUDPSPS" value="1000"/>
|
124
|
+
<parameter id="KiPSPP" name="KiPSPP" value="4000"/>
|
125
|
+
<parameter id="VappSPSSPP" name="VappSPSSPP" value="797"/>
|
126
|
+
<parameter id="KmF6PSPSSPP" name="KmF6PSPSSPP" value="900"/>
|
127
|
+
<parameter id="KmUDPGSPSSPP" name="KmUDPGSPSSPP" value="2000"/>
|
128
|
+
<parameter id="KiSucroseSPSSPP" name="KiSucroseSPSSPP" value="5000"/>
|
129
|
+
<parameter id="KeqSPSSPP" name="KeqSPSSPP" value="7770"/>
|
130
|
+
<parameter id="VratioSPSSPP" name="VratioSPSSPP" value="1000"/>
|
131
|
+
<parameter id="VmaxSSynth" name="VmaxSSynth" value="100"/>
|
132
|
+
<parameter id="KeqSSynth" name="KeqSSynth" value="2.4"/>
|
133
|
+
<parameter id="KmSSynthFructose" name="KmSSynthFructose" value="5900"/>
|
134
|
+
<parameter id="KmSSynthUDPG" name="KmSSynthUDPG" value="1650"/>
|
135
|
+
<parameter id="KmSSynthSucrose" name="KmSSynthSucrose" value="55000"/>
|
136
|
+
<parameter id="KmSSynthUDP" name="KmSSynthUDP" value="140"/>
|
137
|
+
<parameter id="KiSSynthGlucose" name="KiSSynthGlucose" value="12000"/>
|
138
|
+
<parameter id="VSucUpt" name="VSucUpt" value="1"/>
|
139
|
+
<parameter id="kforwardSucUpt" name="kforwardSucUpt" value="0.01"/>
|
140
|
+
<parameter id="kbackwardSucUpt" name="kbackwardSucUpt" value="0.01"/>
|
141
|
+
<parameter id="Vmaxinv" name="Vmaxinv" value="33"/>
|
142
|
+
<parameter id="KmSucroseinv" name="KmSucroseinv" value="28000"/>
|
143
|
+
<parameter id="KiFructoseinv" name="KiFructoseinv" value="180"/>
|
144
|
+
<parameter id="KiGlucoseinv" name="KiGlucoseinv" value="1000"/>
|
145
|
+
<parameter id="VmaxFK" name="VmaxFK" value="376"/>
|
146
|
+
<parameter id="KmFructoseFK" name="KmFructoseFK" value="90"/>
|
147
|
+
<parameter id="KmATPFK" name="KmATPFK" value="35"/>
|
148
|
+
<parameter id="KiFructoseFK" name="KiFructoseFK" value="5000"/>
|
149
|
+
<parameter id="KmADPFK" name="KmADPFK" value="13"/>
|
150
|
+
<parameter id="KmF6PFK" name="KmF6PFK" value="1300"/>
|
151
|
+
<parameter id="KmGlucoseHK1" name="KmGlucoseHK1" value="41"/>
|
152
|
+
<parameter id="KmFructoseHK1" name="KmFructoseHK1" value="11000"/>
|
153
|
+
<parameter id="KmATPHK1" name="KmATPHK1" value="80"/>
|
154
|
+
<parameter id="KiADPHK1" name="KiADPHK1" value="20"/>
|
155
|
+
<parameter id="KiG6PHK1" name="KiG6PHK1" value="4100"/>
|
156
|
+
<parameter id="VmaxHK1" name="VmaxHK1" value="80"/>
|
157
|
+
<parameter id="VmaxHK2" name="VmaxHK2" value="80"/>
|
158
|
+
<parameter id="VmaxGK" name="VmaxGK" value="160"/>
|
159
|
+
<parameter id="KmGlucoseHK2" name="KmGlucoseHK2" value="130"/>
|
160
|
+
<parameter id="KmFructoseHK2" name="KmFructoseHK2" value="22000"/>
|
161
|
+
<parameter id="KmATPHK2" name="KmATPHK2" value="280"/>
|
162
|
+
<parameter id="KiADPHK2" name="KiADPHK2" value="100"/>
|
163
|
+
<parameter id="VNDPK" name="VNDPK" value="1"/>
|
164
|
+
<parameter id="kforwardNDPK" name="kforwardNDPK" value="0.001"/>
|
165
|
+
<parameter id="kbackwardNDPK" name="kbackwardNDPK" value="0.001"/>
|
166
|
+
<parameter id="VAT" name="VAT" value="1"/>
|
167
|
+
<parameter id="kforwardAT" name="kforwardAT" value="0.002"/>
|
168
|
+
<parameter id="kbackwardAT" name="kbackwardAT" value="0.002"/>
|
169
|
+
<parameter id="VPexp" name="VPexp" value="1"/>
|
170
|
+
<parameter id="kforwardPexp" name="kforwardPexp" value="0.3"/>
|
171
|
+
<parameter id="kbackwardPexp" name="kbackwardPexp" value="0.1"/>
|
172
|
+
<parameter id="VATPcons" name="VATPcons" value="1"/>
|
173
|
+
<parameter id="kATPcons" name="kATPcons" value="3"/>
|
174
|
+
</listOfParameters>
|
175
|
+
<listOfReactions>
|
176
|
+
<reaction id="vAGPase" name="vAGPase">
|
177
|
+
<listOfReactants>
|
178
|
+
<speciesReference species="G1Pam"/>
|
179
|
+
<speciesReference species="ATPam"/>
|
180
|
+
</listOfReactants>
|
181
|
+
<listOfProducts>
|
182
|
+
<speciesReference species="ADPGam"/>
|
183
|
+
<speciesReference species="PPam"/>
|
184
|
+
</listOfProducts>
|
185
|
+
<listOfModifiers>
|
186
|
+
<modifierSpeciesReference species="PGA3am"/>
|
187
|
+
<modifierSpeciesReference species="Pam"/>
|
188
|
+
</listOfModifiers>
|
189
|
+
<kineticLaw>
|
190
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
191
|
+
<apply>
|
192
|
+
<divide/>
|
193
|
+
<apply>
|
194
|
+
<divide/>
|
195
|
+
<apply>
|
196
|
+
<times/>
|
197
|
+
<ci> VmaxAGPase </ci>
|
198
|
+
<apply>
|
199
|
+
<minus/>
|
200
|
+
<apply>
|
201
|
+
<times/>
|
202
|
+
<ci> G1Pam </ci>
|
203
|
+
<ci> ATPam </ci>
|
204
|
+
</apply>
|
205
|
+
<apply>
|
206
|
+
<times/>
|
207
|
+
<ci> ADPGam </ci>
|
208
|
+
<ci> PPam </ci>
|
209
|
+
</apply>
|
210
|
+
</apply>
|
211
|
+
<apply>
|
212
|
+
<plus/>
|
213
|
+
<cn type="integer"> 1 </cn>
|
214
|
+
<apply>
|
215
|
+
<divide/>
|
216
|
+
<ci> PGA3am </ci>
|
217
|
+
<ci> KaPGA3AGPase </ci>
|
218
|
+
</apply>
|
219
|
+
</apply>
|
220
|
+
</apply>
|
221
|
+
<apply>
|
222
|
+
<times/>
|
223
|
+
<apply>
|
224
|
+
<plus/>
|
225
|
+
<apply>
|
226
|
+
<times/>
|
227
|
+
<ci> KmG1PAGPase </ci>
|
228
|
+
<apply>
|
229
|
+
<plus/>
|
230
|
+
<cn type="integer"> 1 </cn>
|
231
|
+
<apply>
|
232
|
+
<divide/>
|
233
|
+
<ci> PPam </ci>
|
234
|
+
<ci> KmPPAGPase </ci>
|
235
|
+
</apply>
|
236
|
+
</apply>
|
237
|
+
</apply>
|
238
|
+
<ci> G1Pam </ci>
|
239
|
+
</apply>
|
240
|
+
<apply>
|
241
|
+
<plus/>
|
242
|
+
<apply>
|
243
|
+
<times/>
|
244
|
+
<ci> KmATPAGPase </ci>
|
245
|
+
<apply>
|
246
|
+
<plus/>
|
247
|
+
<cn type="integer"> 1 </cn>
|
248
|
+
<apply>
|
249
|
+
<divide/>
|
250
|
+
<ci> ADPGam </ci>
|
251
|
+
<ci> KmADPGAGPase </ci>
|
252
|
+
</apply>
|
253
|
+
</apply>
|
254
|
+
</apply>
|
255
|
+
<ci> ATPam </ci>
|
256
|
+
</apply>
|
257
|
+
</apply>
|
258
|
+
</apply>
|
259
|
+
<apply>
|
260
|
+
<plus/>
|
261
|
+
<cn type="integer"> 1 </cn>
|
262
|
+
<apply>
|
263
|
+
<divide/>
|
264
|
+
<ci> Pam </ci>
|
265
|
+
<ci> KiPAGPase </ci>
|
266
|
+
</apply>
|
267
|
+
</apply>
|
268
|
+
</apply>
|
269
|
+
</math>
|
270
|
+
</kineticLaw>
|
271
|
+
</reaction>
|
272
|
+
<reaction id="vStSynth" name="vStSynth">
|
273
|
+
<listOfReactants>
|
274
|
+
<speciesReference species="ADPGam"/>
|
275
|
+
<speciesReference species="xstarch"/>
|
276
|
+
</listOfReactants>
|
277
|
+
<listOfProducts>
|
278
|
+
<speciesReference species="ADPam"/>
|
279
|
+
</listOfProducts>
|
280
|
+
<kineticLaw>
|
281
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
282
|
+
<apply>
|
283
|
+
<divide/>
|
284
|
+
<apply>
|
285
|
+
<times/>
|
286
|
+
<ci> VmaxStSynth </ci>
|
287
|
+
<ci> ADPGam </ci>
|
288
|
+
</apply>
|
289
|
+
<apply>
|
290
|
+
<plus/>
|
291
|
+
<ci> KmADPGStSynth </ci>
|
292
|
+
<ci> ADPGam </ci>
|
293
|
+
</apply>
|
294
|
+
</apply>
|
295
|
+
</math>
|
296
|
+
</kineticLaw>
|
297
|
+
</reaction>
|
298
|
+
<reaction id="vpPPase" name="vpPPase">
|
299
|
+
<listOfReactants>
|
300
|
+
<speciesReference species="PPam"/>
|
301
|
+
</listOfReactants>
|
302
|
+
<listOfProducts>
|
303
|
+
<speciesReference species="Pam" stoichiometry="2"/>
|
304
|
+
</listOfProducts>
|
305
|
+
<kineticLaw>
|
306
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
307
|
+
<apply>
|
308
|
+
<times/>
|
309
|
+
<ci> VmaxpPPase </ci>
|
310
|
+
<apply>
|
311
|
+
<minus/>
|
312
|
+
<cn type="integer"> 1 </cn>
|
313
|
+
<apply>
|
314
|
+
<divide/>
|
315
|
+
<apply>
|
316
|
+
<divide/>
|
317
|
+
<apply>
|
318
|
+
<times/>
|
319
|
+
<ci> Pam </ci>
|
320
|
+
<ci> Pam </ci>
|
321
|
+
</apply>
|
322
|
+
<ci> PPam </ci>
|
323
|
+
</apply>
|
324
|
+
<ci> KeqpPPase </ci>
|
325
|
+
</apply>
|
326
|
+
</apply>
|
327
|
+
</apply>
|
328
|
+
</math>
|
329
|
+
</kineticLaw>
|
330
|
+
</reaction>
|
331
|
+
<reaction id="vStPase" name="vStPase">
|
332
|
+
<listOfReactants>
|
333
|
+
<speciesReference species="xstarch"/>
|
334
|
+
<speciesReference species="Pam"/>
|
335
|
+
</listOfReactants>
|
336
|
+
<listOfProducts>
|
337
|
+
<speciesReference species="G1Pam"/>
|
338
|
+
</listOfProducts>
|
339
|
+
<kineticLaw>
|
340
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
341
|
+
<apply>
|
342
|
+
<divide/>
|
343
|
+
<apply>
|
344
|
+
<times/>
|
345
|
+
<ci> VforwardStPase </ci>
|
346
|
+
<apply>
|
347
|
+
<minus/>
|
348
|
+
<ci> Pam </ci>
|
349
|
+
<apply>
|
350
|
+
<divide/>
|
351
|
+
<ci> G1Pam </ci>
|
352
|
+
<ci> KeqStPase </ci>
|
353
|
+
</apply>
|
354
|
+
</apply>
|
355
|
+
</apply>
|
356
|
+
<apply>
|
357
|
+
<plus/>
|
358
|
+
<ci> KmPStPase </ci>
|
359
|
+
<ci> Pam </ci>
|
360
|
+
<apply>
|
361
|
+
<divide/>
|
362
|
+
<apply>
|
363
|
+
<times/>
|
364
|
+
<ci> G1Pam </ci>
|
365
|
+
<ci> KmPStPase </ci>
|
366
|
+
</apply>
|
367
|
+
<ci> KmG1PStPase </ci>
|
368
|
+
</apply>
|
369
|
+
</apply>
|
370
|
+
</apply>
|
371
|
+
</math>
|
372
|
+
</kineticLaw>
|
373
|
+
</reaction>
|
374
|
+
<reaction id="vdegr" name="vdegr">
|
375
|
+
<listOfReactants>
|
376
|
+
<speciesReference species="xstarch"/>
|
377
|
+
</listOfReactants>
|
378
|
+
<listOfProducts>
|
379
|
+
<speciesReference species="Glucoseam"/>
|
380
|
+
</listOfProducts>
|
381
|
+
<kineticLaw>
|
382
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
383
|
+
<apply>
|
384
|
+
<divide/>
|
385
|
+
<ci> Vmaxdegr </ci>
|
386
|
+
<apply>
|
387
|
+
<plus/>
|
388
|
+
<cn type="integer"> 1 </cn>
|
389
|
+
<apply>
|
390
|
+
<divide/>
|
391
|
+
<ci> Glucoseam </ci>
|
392
|
+
<ci> KiGlucosedegr </ci>
|
393
|
+
</apply>
|
394
|
+
</apply>
|
395
|
+
</apply>
|
396
|
+
</math>
|
397
|
+
</kineticLaw>
|
398
|
+
</reaction>
|
399
|
+
<reaction id="vGexp" name="vGexp">
|
400
|
+
<listOfReactants>
|
401
|
+
<speciesReference species="Glucoseam"/>
|
402
|
+
</listOfReactants>
|
403
|
+
<listOfProducts>
|
404
|
+
<speciesReference species="Glucosecyt"/>
|
405
|
+
</listOfProducts>
|
406
|
+
<kineticLaw>
|
407
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
408
|
+
<apply>
|
409
|
+
<times/>
|
410
|
+
<ci> VGexp </ci>
|
411
|
+
<apply>
|
412
|
+
<minus/>
|
413
|
+
<apply>
|
414
|
+
<times/>
|
415
|
+
<ci> kforwardGexp </ci>
|
416
|
+
<ci> Glucoseam </ci>
|
417
|
+
</apply>
|
418
|
+
<apply>
|
419
|
+
<times/>
|
420
|
+
<ci> kbackwardGexp </ci>
|
421
|
+
<ci> Glucosecyt </ci>
|
422
|
+
</apply>
|
423
|
+
</apply>
|
424
|
+
</apply>
|
425
|
+
</math>
|
426
|
+
</kineticLaw>
|
427
|
+
</reaction>
|
428
|
+
<reaction id="vG6Pexp" name="vG6Pexp">
|
429
|
+
<listOfReactants>
|
430
|
+
<speciesReference species="G6Pam"/>
|
431
|
+
<speciesReference species="Pcyt"/>
|
432
|
+
</listOfReactants>
|
433
|
+
<listOfProducts>
|
434
|
+
<speciesReference species="G6Pcyt"/>
|
435
|
+
<speciesReference species="Pam"/>
|
436
|
+
</listOfProducts>
|
437
|
+
<kineticLaw>
|
438
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
439
|
+
<apply>
|
440
|
+
<times/>
|
441
|
+
<ci> VG6Pexp </ci>
|
442
|
+
<apply>
|
443
|
+
<minus/>
|
444
|
+
<apply>
|
445
|
+
<times/>
|
446
|
+
<ci> kforwardG6Pexp </ci>
|
447
|
+
<ci> G6Pam </ci>
|
448
|
+
<ci> Pcyt </ci>
|
449
|
+
</apply>
|
450
|
+
<apply>
|
451
|
+
<times/>
|
452
|
+
<ci> kbackwardG6Pexp </ci>
|
453
|
+
<ci> G6Pcyt </ci>
|
454
|
+
<ci> Pam </ci>
|
455
|
+
</apply>
|
456
|
+
</apply>
|
457
|
+
</apply>
|
458
|
+
</math>
|
459
|
+
</kineticLaw>
|
460
|
+
</reaction>
|
461
|
+
<reaction id="vpPGM" name="vpPGM">
|
462
|
+
<listOfReactants>
|
463
|
+
<speciesReference species="G1Pam"/>
|
464
|
+
</listOfReactants>
|
465
|
+
<listOfProducts>
|
466
|
+
<speciesReference species="G6Pam"/>
|
467
|
+
</listOfProducts>
|
468
|
+
<kineticLaw>
|
469
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
470
|
+
<apply>
|
471
|
+
<times/>
|
472
|
+
<ci> VmaxpPGM </ci>
|
473
|
+
<apply>
|
474
|
+
<minus/>
|
475
|
+
<cn type="integer"> 1 </cn>
|
476
|
+
<apply>
|
477
|
+
<divide/>
|
478
|
+
<apply>
|
479
|
+
<divide/>
|
480
|
+
<ci> G6Pam </ci>
|
481
|
+
<ci> G1Pam </ci>
|
482
|
+
</apply>
|
483
|
+
<ci> KeqpPGM </ci>
|
484
|
+
</apply>
|
485
|
+
</apply>
|
486
|
+
</apply>
|
487
|
+
</math>
|
488
|
+
</kineticLaw>
|
489
|
+
</reaction>
|
490
|
+
<reaction id="vcPGM" name="vcPGM">
|
491
|
+
<listOfReactants>
|
492
|
+
<speciesReference species="G1Pcyt"/>
|
493
|
+
</listOfReactants>
|
494
|
+
<listOfProducts>
|
495
|
+
<speciesReference species="G6Pcyt"/>
|
496
|
+
</listOfProducts>
|
497
|
+
<kineticLaw>
|
498
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
499
|
+
<apply>
|
500
|
+
<times/>
|
501
|
+
<ci> VmaxcPGM </ci>
|
502
|
+
<apply>
|
503
|
+
<minus/>
|
504
|
+
<cn type="integer"> 1 </cn>
|
505
|
+
<apply>
|
506
|
+
<divide/>
|
507
|
+
<apply>
|
508
|
+
<divide/>
|
509
|
+
<ci> G6Pcyt </ci>
|
510
|
+
<ci> G1Pcyt </ci>
|
511
|
+
</apply>
|
512
|
+
<ci> KeqcPGM </ci>
|
513
|
+
</apply>
|
514
|
+
</apply>
|
515
|
+
</apply>
|
516
|
+
</math>
|
517
|
+
</kineticLaw>
|
518
|
+
</reaction>
|
519
|
+
<reaction id="vPGI" name="vPGI">
|
520
|
+
<listOfReactants>
|
521
|
+
<speciesReference species="G6Pcyt"/>
|
522
|
+
</listOfReactants>
|
523
|
+
<listOfProducts>
|
524
|
+
<speciesReference species="F6Pcyt"/>
|
525
|
+
</listOfProducts>
|
526
|
+
<listOfModifiers>
|
527
|
+
<modifierSpeciesReference species="F16BPcyt"/>
|
528
|
+
<modifierSpeciesReference species="PEPcyt"/>
|
529
|
+
</listOfModifiers>
|
530
|
+
<kineticLaw>
|
531
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
532
|
+
<apply>
|
533
|
+
<divide/>
|
534
|
+
<apply>
|
535
|
+
<times/>
|
536
|
+
<ci> VmaxPGI </ci>
|
537
|
+
<apply>
|
538
|
+
<minus/>
|
539
|
+
<ci> G6Pcyt </ci>
|
540
|
+
<apply>
|
541
|
+
<divide/>
|
542
|
+
<ci> F6Pcyt </ci>
|
543
|
+
<ci> KeqPGI </ci>
|
544
|
+
</apply>
|
545
|
+
</apply>
|
546
|
+
</apply>
|
547
|
+
<apply>
|
548
|
+
<plus/>
|
549
|
+
<ci> KmG6PPGI </ci>
|
550
|
+
<ci> G6Pcyt </ci>
|
551
|
+
<apply>
|
552
|
+
<divide/>
|
553
|
+
<apply>
|
554
|
+
<times/>
|
555
|
+
<ci> F6Pcyt </ci>
|
556
|
+
<ci> KmG6PPGI </ci>
|
557
|
+
</apply>
|
558
|
+
<ci> KmF6PPGI </ci>
|
559
|
+
</apply>
|
560
|
+
<apply>
|
561
|
+
<divide/>
|
562
|
+
<apply>
|
563
|
+
<times/>
|
564
|
+
<ci> F16BPcyt </ci>
|
565
|
+
<ci> KmG6PPGI </ci>
|
566
|
+
</apply>
|
567
|
+
<ci> KiF16BPPGI </ci>
|
568
|
+
</apply>
|
569
|
+
<apply>
|
570
|
+
<divide/>
|
571
|
+
<apply>
|
572
|
+
<times/>
|
573
|
+
<ci> PEPcyt </ci>
|
574
|
+
<ci> KmG6PPGI </ci>
|
575
|
+
</apply>
|
576
|
+
<ci> KiPEPPGI </ci>
|
577
|
+
</apply>
|
578
|
+
</apply>
|
579
|
+
</apply>
|
580
|
+
</math>
|
581
|
+
</kineticLaw>
|
582
|
+
</reaction>
|
583
|
+
<reaction id="vPFK" name="vPFK">
|
584
|
+
<listOfReactants>
|
585
|
+
<speciesReference species="F6Pcyt"/>
|
586
|
+
<speciesReference species="ATPcyt"/>
|
587
|
+
</listOfReactants>
|
588
|
+
<listOfProducts>
|
589
|
+
<speciesReference species="F16BPcyt"/>
|
590
|
+
<speciesReference species="ADPcyt"/>
|
591
|
+
</listOfProducts>
|
592
|
+
<listOfModifiers>
|
593
|
+
<modifierSpeciesReference species="PEPcyt"/>
|
594
|
+
</listOfModifiers>
|
595
|
+
<kineticLaw>
|
596
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
597
|
+
<apply>
|
598
|
+
<divide/>
|
599
|
+
<apply>
|
600
|
+
<times/>
|
601
|
+
<ci> VmaxPFK </ci>
|
602
|
+
<apply>
|
603
|
+
<divide/>
|
604
|
+
<ci> F6Pcyt </ci>
|
605
|
+
<ci> KmF6PPFK </ci>
|
606
|
+
</apply>
|
607
|
+
<apply>
|
608
|
+
<power/>
|
609
|
+
<apply>
|
610
|
+
<plus/>
|
611
|
+
<cn type="integer"> 1 </cn>
|
612
|
+
<apply>
|
613
|
+
<divide/>
|
614
|
+
<ci> F6Pcyt </ci>
|
615
|
+
<ci> KmF6PPFK </ci>
|
616
|
+
</apply>
|
617
|
+
</apply>
|
618
|
+
<apply>
|
619
|
+
<minus/>
|
620
|
+
<ci> nPFK </ci>
|
621
|
+
<cn type="integer"> 1 </cn>
|
622
|
+
</apply>
|
623
|
+
</apply>
|
624
|
+
</apply>
|
625
|
+
<apply>
|
626
|
+
<plus/>
|
627
|
+
<apply>
|
628
|
+
<power/>
|
629
|
+
<apply>
|
630
|
+
<plus/>
|
631
|
+
<cn type="integer"> 1 </cn>
|
632
|
+
<apply>
|
633
|
+
<divide/>
|
634
|
+
<ci> F6Pcyt </ci>
|
635
|
+
<ci> KmF6PPFK </ci>
|
636
|
+
</apply>
|
637
|
+
</apply>
|
638
|
+
<ci> nPFK </ci>
|
639
|
+
</apply>
|
640
|
+
<apply>
|
641
|
+
<times/>
|
642
|
+
<ci> LPFK </ci>
|
643
|
+
<apply>
|
644
|
+
<power/>
|
645
|
+
<apply>
|
646
|
+
<plus/>
|
647
|
+
<cn type="integer"> 1 </cn>
|
648
|
+
<apply>
|
649
|
+
<divide/>
|
650
|
+
<ci> PEPcyt </ci>
|
651
|
+
<ci> KiPEPPFK </ci>
|
652
|
+
</apply>
|
653
|
+
</apply>
|
654
|
+
<ci> nPFK </ci>
|
655
|
+
</apply>
|
656
|
+
</apply>
|
657
|
+
</apply>
|
658
|
+
</apply>
|
659
|
+
</math>
|
660
|
+
</kineticLaw>
|
661
|
+
</reaction>
|
662
|
+
<reaction id="vPFP" name="vPFP">
|
663
|
+
<listOfReactants>
|
664
|
+
<speciesReference species="F6Pcyt"/>
|
665
|
+
<speciesReference species="PPcyt"/>
|
666
|
+
</listOfReactants>
|
667
|
+
<listOfProducts>
|
668
|
+
<speciesReference species="F16BPcyt"/>
|
669
|
+
<speciesReference species="Pcyt"/>
|
670
|
+
</listOfProducts>
|
671
|
+
<kineticLaw>
|
672
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
673
|
+
<apply>
|
674
|
+
<divide/>
|
675
|
+
<apply>
|
676
|
+
<times/>
|
677
|
+
<ci> VmaxPFP </ci>
|
678
|
+
<apply>
|
679
|
+
<divide/>
|
680
|
+
<apply>
|
681
|
+
<divide/>
|
682
|
+
<cn type="integer"> 1 </cn>
|
683
|
+
<ci> KmF6PPFP </ci>
|
684
|
+
</apply>
|
685
|
+
<ci> KmPPPFP </ci>
|
686
|
+
</apply>
|
687
|
+
<apply>
|
688
|
+
<minus/>
|
689
|
+
<apply>
|
690
|
+
<times/>
|
691
|
+
<ci> F6Pcyt </ci>
|
692
|
+
<ci> PPcyt </ci>
|
693
|
+
</apply>
|
694
|
+
<apply>
|
695
|
+
<divide/>
|
696
|
+
<apply>
|
697
|
+
<times/>
|
698
|
+
<ci> F16BPcyt </ci>
|
699
|
+
<ci> Pcyt </ci>
|
700
|
+
</apply>
|
701
|
+
<ci> KeqPFP </ci>
|
702
|
+
</apply>
|
703
|
+
</apply>
|
704
|
+
</apply>
|
705
|
+
<apply>
|
706
|
+
<plus/>
|
707
|
+
<cn type="integer"> 1 </cn>
|
708
|
+
<apply>
|
709
|
+
<divide/>
|
710
|
+
<ci> F6Pcyt </ci>
|
711
|
+
<ci> KmF6PPFP </ci>
|
712
|
+
</apply>
|
713
|
+
<apply>
|
714
|
+
<divide/>
|
715
|
+
<ci> PPcyt </ci>
|
716
|
+
<ci> KmPPPFP </ci>
|
717
|
+
</apply>
|
718
|
+
<apply>
|
719
|
+
<divide/>
|
720
|
+
<ci> F16BPcyt </ci>
|
721
|
+
<ci> KmF16BPPFP </ci>
|
722
|
+
</apply>
|
723
|
+
<apply>
|
724
|
+
<divide/>
|
725
|
+
<ci> Pcyt </ci>
|
726
|
+
<ci> KmPPFP </ci>
|
727
|
+
</apply>
|
728
|
+
</apply>
|
729
|
+
</apply>
|
730
|
+
</math>
|
731
|
+
</kineticLaw>
|
732
|
+
</reaction>
|
733
|
+
<reaction id="vald" name="vald">
|
734
|
+
<listOfReactants>
|
735
|
+
<speciesReference species="F16BPcyt"/>
|
736
|
+
</listOfReactants>
|
737
|
+
<listOfProducts>
|
738
|
+
<speciesReference species="GAPcyt"/>
|
739
|
+
<speciesReference species="DHAPcyt"/>
|
740
|
+
</listOfProducts>
|
741
|
+
<kineticLaw>
|
742
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
743
|
+
<apply>
|
744
|
+
<divide/>
|
745
|
+
<apply>
|
746
|
+
<times/>
|
747
|
+
<ci> Vmaxald </ci>
|
748
|
+
<apply>
|
749
|
+
<divide/>
|
750
|
+
<ci> F16BPcyt </ci>
|
751
|
+
<ci> KmF16BPald </ci>
|
752
|
+
</apply>
|
753
|
+
<apply>
|
754
|
+
<minus/>
|
755
|
+
<cn type="integer"> 1 </cn>
|
756
|
+
<apply>
|
757
|
+
<divide/>
|
758
|
+
<apply>
|
759
|
+
<divide/>
|
760
|
+
<apply>
|
761
|
+
<times/>
|
762
|
+
<ci> GAPcyt </ci>
|
763
|
+
<ci> DHAPcyt </ci>
|
764
|
+
</apply>
|
765
|
+
<ci> F16BPcyt </ci>
|
766
|
+
</apply>
|
767
|
+
<ci> Keqald </ci>
|
768
|
+
</apply>
|
769
|
+
</apply>
|
770
|
+
</apply>
|
771
|
+
<apply>
|
772
|
+
<plus/>
|
773
|
+
<cn type="integer"> 1 </cn>
|
774
|
+
<apply>
|
775
|
+
<divide/>
|
776
|
+
<ci> F16BPcyt </ci>
|
777
|
+
<ci> KmF16BPald </ci>
|
778
|
+
</apply>
|
779
|
+
<apply>
|
780
|
+
<divide/>
|
781
|
+
<ci> GAPcyt </ci>
|
782
|
+
<ci> KmGAPald </ci>
|
783
|
+
</apply>
|
784
|
+
<apply>
|
785
|
+
<divide/>
|
786
|
+
<ci> DHAPcyt </ci>
|
787
|
+
<ci> KmDHAPald </ci>
|
788
|
+
</apply>
|
789
|
+
<apply>
|
790
|
+
<divide/>
|
791
|
+
<apply>
|
792
|
+
<times/>
|
793
|
+
<ci> F16BPcyt </ci>
|
794
|
+
<ci> GAPcyt </ci>
|
795
|
+
</apply>
|
796
|
+
<apply>
|
797
|
+
<times/>
|
798
|
+
<ci> KmF16BPald </ci>
|
799
|
+
<ci> KiGAPald </ci>
|
800
|
+
</apply>
|
801
|
+
</apply>
|
802
|
+
<apply>
|
803
|
+
<divide/>
|
804
|
+
<apply>
|
805
|
+
<times/>
|
806
|
+
<ci> GAPcyt </ci>
|
807
|
+
<ci> DHAPcyt </ci>
|
808
|
+
</apply>
|
809
|
+
<apply>
|
810
|
+
<times/>
|
811
|
+
<ci> KmGAPald </ci>
|
812
|
+
<ci> KmDHAPald </ci>
|
813
|
+
</apply>
|
814
|
+
</apply>
|
815
|
+
</apply>
|
816
|
+
</apply>
|
817
|
+
</math>
|
818
|
+
</kineticLaw>
|
819
|
+
</reaction>
|
820
|
+
<reaction id="vTPI" name="vTPI">
|
821
|
+
<listOfReactants>
|
822
|
+
<speciesReference species="DHAPcyt"/>
|
823
|
+
</listOfReactants>
|
824
|
+
<listOfProducts>
|
825
|
+
<speciesReference species="GAPcyt"/>
|
826
|
+
</listOfProducts>
|
827
|
+
<kineticLaw>
|
828
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
829
|
+
<apply>
|
830
|
+
<divide/>
|
831
|
+
<apply>
|
832
|
+
<times/>
|
833
|
+
<ci> VmaxTPI </ci>
|
834
|
+
<apply>
|
835
|
+
<minus/>
|
836
|
+
<ci> DHAPcyt </ci>
|
837
|
+
<apply>
|
838
|
+
<divide/>
|
839
|
+
<ci> GAPcyt </ci>
|
840
|
+
<ci> KeqTPI </ci>
|
841
|
+
</apply>
|
842
|
+
</apply>
|
843
|
+
</apply>
|
844
|
+
<apply>
|
845
|
+
<plus/>
|
846
|
+
<ci> KmDHAPTPI </ci>
|
847
|
+
<ci> DHAPcyt </ci>
|
848
|
+
<apply>
|
849
|
+
<divide/>
|
850
|
+
<apply>
|
851
|
+
<times/>
|
852
|
+
<ci> GAPcyt </ci>
|
853
|
+
<ci> KmGAPTPI </ci>
|
854
|
+
</apply>
|
855
|
+
<ci> KmGAPTPI </ci>
|
856
|
+
</apply>
|
857
|
+
</apply>
|
858
|
+
</apply>
|
859
|
+
</math>
|
860
|
+
</kineticLaw>
|
861
|
+
</reaction>
|
862
|
+
<reaction id="vGAPDH" name="vGAPDH">
|
863
|
+
<listOfReactants>
|
864
|
+
<speciesReference species="GAPcyt" stoichiometry="6"/>
|
865
|
+
<speciesReference species="ADPcyt" stoichiometry="17"/>
|
866
|
+
<speciesReference species="Pcyt" stoichiometry="17"/>
|
867
|
+
</listOfReactants>
|
868
|
+
<listOfProducts>
|
869
|
+
<speciesReference species="PGA3cyt" stoichiometry="6"/>
|
870
|
+
<speciesReference species="ATPcyt" stoichiometry="17"/>
|
871
|
+
</listOfProducts>
|
872
|
+
<kineticLaw>
|
873
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
874
|
+
<apply>
|
875
|
+
<times/>
|
876
|
+
<apply>
|
877
|
+
<divide/>
|
878
|
+
<ci> VmaxGAPDH </ci>
|
879
|
+
<cn type="integer"> 6 </cn>
|
880
|
+
</apply>
|
881
|
+
<apply>
|
882
|
+
<minus/>
|
883
|
+
<cn type="integer"> 1 </cn>
|
884
|
+
<apply>
|
885
|
+
<divide/>
|
886
|
+
<apply>
|
887
|
+
<divide/>
|
888
|
+
<apply>
|
889
|
+
<times/>
|
890
|
+
<ci> PGA3cyt </ci>
|
891
|
+
<ci> ATPcyt </ci>
|
892
|
+
</apply>
|
893
|
+
<apply>
|
894
|
+
<times/>
|
895
|
+
<ci> GAPcyt </ci>
|
896
|
+
<ci> Pcyt </ci>
|
897
|
+
<ci> ADPcyt </ci>
|
898
|
+
</apply>
|
899
|
+
</apply>
|
900
|
+
<ci> KeqGAPDH </ci>
|
901
|
+
</apply>
|
902
|
+
</apply>
|
903
|
+
</apply>
|
904
|
+
</math>
|
905
|
+
</kineticLaw>
|
906
|
+
</reaction>
|
907
|
+
<reaction id="vPGA3imp" name="vPGA3imp">
|
908
|
+
<listOfReactants>
|
909
|
+
<speciesReference species="PGA3cyt"/>
|
910
|
+
<speciesReference species="G6Pam"/>
|
911
|
+
</listOfReactants>
|
912
|
+
<listOfProducts>
|
913
|
+
<speciesReference species="PGA3am"/>
|
914
|
+
<speciesReference species="G6Pcyt"/>
|
915
|
+
</listOfProducts>
|
916
|
+
<kineticLaw>
|
917
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
918
|
+
<apply>
|
919
|
+
<times/>
|
920
|
+
<ci> VPGA3imp </ci>
|
921
|
+
<apply>
|
922
|
+
<minus/>
|
923
|
+
<apply>
|
924
|
+
<times/>
|
925
|
+
<ci> kforwardPGA3imp </ci>
|
926
|
+
<ci> PGA3cyt </ci>
|
927
|
+
<ci> G6Pam </ci>
|
928
|
+
</apply>
|
929
|
+
<apply>
|
930
|
+
<times/>
|
931
|
+
<ci> kbackwardPGA3imp </ci>
|
932
|
+
<ci> PGA3am </ci>
|
933
|
+
<ci> G6Pcyt </ci>
|
934
|
+
</apply>
|
935
|
+
</apply>
|
936
|
+
</apply>
|
937
|
+
</math>
|
938
|
+
</kineticLaw>
|
939
|
+
</reaction>
|
940
|
+
<reaction id="vPGlyM" name="vPGlyM">
|
941
|
+
<listOfReactants>
|
942
|
+
<speciesReference species="PGA3cyt"/>
|
943
|
+
</listOfReactants>
|
944
|
+
<listOfProducts>
|
945
|
+
<speciesReference species="PGA2cyt"/>
|
946
|
+
</listOfProducts>
|
947
|
+
<kineticLaw>
|
948
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
949
|
+
<apply>
|
950
|
+
<divide/>
|
951
|
+
<apply>
|
952
|
+
<times/>
|
953
|
+
<ci> VmaxPGlyM </ci>
|
954
|
+
<apply>
|
955
|
+
<minus/>
|
956
|
+
<ci> PGA3cyt </ci>
|
957
|
+
<apply>
|
958
|
+
<divide/>
|
959
|
+
<ci> PGA2cyt </ci>
|
960
|
+
<ci> KeqPGlyM </ci>
|
961
|
+
</apply>
|
962
|
+
</apply>
|
963
|
+
</apply>
|
964
|
+
<apply>
|
965
|
+
<plus/>
|
966
|
+
<ci> KmPGA3PGlyM </ci>
|
967
|
+
<ci> PGA3cyt </ci>
|
968
|
+
<apply>
|
969
|
+
<divide/>
|
970
|
+
<apply>
|
971
|
+
<times/>
|
972
|
+
<ci> PGA2cyt </ci>
|
973
|
+
<ci> KmPGA3PGlyM </ci>
|
974
|
+
</apply>
|
975
|
+
<ci> KmPGA2PGlyM </ci>
|
976
|
+
</apply>
|
977
|
+
</apply>
|
978
|
+
</apply>
|
979
|
+
</math>
|
980
|
+
</kineticLaw>
|
981
|
+
</reaction>
|
982
|
+
<reaction id="veno" name="veno">
|
983
|
+
<listOfReactants>
|
984
|
+
<speciesReference species="PGA2cyt"/>
|
985
|
+
</listOfReactants>
|
986
|
+
<listOfProducts>
|
987
|
+
<speciesReference species="PEPcyt"/>
|
988
|
+
</listOfProducts>
|
989
|
+
<kineticLaw>
|
990
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
991
|
+
<apply>
|
992
|
+
<divide/>
|
993
|
+
<apply>
|
994
|
+
<times/>
|
995
|
+
<ci> Vmaxeno </ci>
|
996
|
+
<apply>
|
997
|
+
<minus/>
|
998
|
+
<ci> PGA2cyt </ci>
|
999
|
+
<apply>
|
1000
|
+
<divide/>
|
1001
|
+
<ci> PEPcyt </ci>
|
1002
|
+
<ci> Keqeno </ci>
|
1003
|
+
</apply>
|
1004
|
+
</apply>
|
1005
|
+
</apply>
|
1006
|
+
<apply>
|
1007
|
+
<plus/>
|
1008
|
+
<ci> KmPGA2eno </ci>
|
1009
|
+
<ci> PGA2cyt </ci>
|
1010
|
+
<apply>
|
1011
|
+
<divide/>
|
1012
|
+
<apply>
|
1013
|
+
<times/>
|
1014
|
+
<ci> PEPcyt </ci>
|
1015
|
+
<ci> KmPGA2eno </ci>
|
1016
|
+
</apply>
|
1017
|
+
<ci> KmPEPeno </ci>
|
1018
|
+
</apply>
|
1019
|
+
</apply>
|
1020
|
+
</apply>
|
1021
|
+
</math>
|
1022
|
+
</kineticLaw>
|
1023
|
+
</reaction>
|
1024
|
+
<reaction id="vPK" name="vPK">
|
1025
|
+
<listOfReactants>
|
1026
|
+
<speciesReference species="PEPcyt"/>
|
1027
|
+
<speciesReference species="ADPcyt"/>
|
1028
|
+
</listOfReactants>
|
1029
|
+
<listOfProducts>
|
1030
|
+
<speciesReference species="xpyruvate"/>
|
1031
|
+
<speciesReference species="ATPcyt"/>
|
1032
|
+
</listOfProducts>
|
1033
|
+
<kineticLaw>
|
1034
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
1035
|
+
<apply>
|
1036
|
+
<divide/>
|
1037
|
+
<apply>
|
1038
|
+
<divide/>
|
1039
|
+
<apply>
|
1040
|
+
<times/>
|
1041
|
+
<ci> VmaxPK </ci>
|
1042
|
+
<ci> PEPcyt </ci>
|
1043
|
+
<ci> ADPcyt </ci>
|
1044
|
+
</apply>
|
1045
|
+
<apply>
|
1046
|
+
<times/>
|
1047
|
+
<ci> KmPEPPK </ci>
|
1048
|
+
<ci> KmADPPK </ci>
|
1049
|
+
</apply>
|
1050
|
+
</apply>
|
1051
|
+
<apply>
|
1052
|
+
<plus/>
|
1053
|
+
<cn type="integer"> 1 </cn>
|
1054
|
+
<apply>
|
1055
|
+
<divide/>
|
1056
|
+
<ci> PEPcyt </ci>
|
1057
|
+
<ci> KmPEPPK </ci>
|
1058
|
+
</apply>
|
1059
|
+
<apply>
|
1060
|
+
<divide/>
|
1061
|
+
<apply>
|
1062
|
+
<times/>
|
1063
|
+
<ci> PEPcyt </ci>
|
1064
|
+
<ci> ADPcyt </ci>
|
1065
|
+
</apply>
|
1066
|
+
<apply>
|
1067
|
+
<times/>
|
1068
|
+
<ci> KmPEPPK </ci>
|
1069
|
+
<ci> KmADPPK </ci>
|
1070
|
+
</apply>
|
1071
|
+
</apply>
|
1072
|
+
<apply>
|
1073
|
+
<divide/>
|
1074
|
+
<ci> ATPcyt </ci>
|
1075
|
+
<ci> KmATPPK </ci>
|
1076
|
+
</apply>
|
1077
|
+
<apply>
|
1078
|
+
<divide/>
|
1079
|
+
<apply>
|
1080
|
+
<times/>
|
1081
|
+
<ci> xpyruvate </ci>
|
1082
|
+
<ci> ATPcyt </ci>
|
1083
|
+
</apply>
|
1084
|
+
<apply>
|
1085
|
+
<times/>
|
1086
|
+
<ci> KmpyruvatePK </ci>
|
1087
|
+
<ci> KmATPPK </ci>
|
1088
|
+
</apply>
|
1089
|
+
</apply>
|
1090
|
+
</apply>
|
1091
|
+
</apply>
|
1092
|
+
</math>
|
1093
|
+
</kineticLaw>
|
1094
|
+
</reaction>
|
1095
|
+
<reaction id="vUGPase" name="vUGPase">
|
1096
|
+
<listOfReactants>
|
1097
|
+
<speciesReference species="G1Pcyt"/>
|
1098
|
+
<speciesReference species="UTPcyt"/>
|
1099
|
+
</listOfReactants>
|
1100
|
+
<listOfProducts>
|
1101
|
+
<speciesReference species="UDPGcyt"/>
|
1102
|
+
<speciesReference species="PPcyt"/>
|
1103
|
+
</listOfProducts>
|
1104
|
+
<kineticLaw>
|
1105
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
1106
|
+
<apply>
|
1107
|
+
<divide/>
|
1108
|
+
<apply>
|
1109
|
+
<times/>
|
1110
|
+
<ci> VforwardUGPase </ci>
|
1111
|
+
<apply>
|
1112
|
+
<minus/>
|
1113
|
+
<apply>
|
1114
|
+
<times/>
|
1115
|
+
<ci> G1Pcyt </ci>
|
1116
|
+
<ci> UTPcyt </ci>
|
1117
|
+
</apply>
|
1118
|
+
<apply>
|
1119
|
+
<divide/>
|
1120
|
+
<apply>
|
1121
|
+
<times/>
|
1122
|
+
<ci> UDPGcyt </ci>
|
1123
|
+
<ci> PPcyt </ci>
|
1124
|
+
</apply>
|
1125
|
+
<ci> KeqUGPase </ci>
|
1126
|
+
</apply>
|
1127
|
+
</apply>
|
1128
|
+
</apply>
|
1129
|
+
<apply>
|
1130
|
+
<times/>
|
1131
|
+
<apply>
|
1132
|
+
<plus/>
|
1133
|
+
<apply>
|
1134
|
+
<times/>
|
1135
|
+
<ci> KmG1PUGPase </ci>
|
1136
|
+
<apply>
|
1137
|
+
<plus/>
|
1138
|
+
<cn type="integer"> 1 </cn>
|
1139
|
+
<apply>
|
1140
|
+
<divide/>
|
1141
|
+
<ci> PPcyt </ci>
|
1142
|
+
<ci> KmPPUGPase </ci>
|
1143
|
+
</apply>
|
1144
|
+
</apply>
|
1145
|
+
</apply>
|
1146
|
+
<ci> G1Pcyt </ci>
|
1147
|
+
</apply>
|
1148
|
+
<apply>
|
1149
|
+
<plus/>
|
1150
|
+
<apply>
|
1151
|
+
<times/>
|
1152
|
+
<ci> KmUTPUGPase </ci>
|
1153
|
+
<apply>
|
1154
|
+
<plus/>
|
1155
|
+
<cn type="integer"> 1 </cn>
|
1156
|
+
<apply>
|
1157
|
+
<divide/>
|
1158
|
+
<ci> UDPGcyt </ci>
|
1159
|
+
<ci> KmUDPGUGPase </ci>
|
1160
|
+
</apply>
|
1161
|
+
</apply>
|
1162
|
+
</apply>
|
1163
|
+
<ci> UTPcyt </ci>
|
1164
|
+
</apply>
|
1165
|
+
</apply>
|
1166
|
+
</apply>
|
1167
|
+
</math>
|
1168
|
+
</kineticLaw>
|
1169
|
+
</reaction>
|
1170
|
+
<reaction id="vSPSSPP" name="vSPSSPP">
|
1171
|
+
<listOfReactants>
|
1172
|
+
<speciesReference species="F6Pcyt"/>
|
1173
|
+
<speciesReference species="UDPGcyt"/>
|
1174
|
+
</listOfReactants>
|
1175
|
+
<listOfProducts>
|
1176
|
+
<speciesReference species="Sucrose"/>
|
1177
|
+
<speciesReference species="Pcyt"/>
|
1178
|
+
<speciesReference species="UDPcyt"/>
|
1179
|
+
</listOfProducts>
|
1180
|
+
<kineticLaw>
|
1181
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
1182
|
+
<apply>
|
1183
|
+
<divide/>
|
1184
|
+
<apply>
|
1185
|
+
<times/>
|
1186
|
+
<ci> VappSPSSPP </ci>
|
1187
|
+
<apply>
|
1188
|
+
<minus/>
|
1189
|
+
<apply>
|
1190
|
+
<times/>
|
1191
|
+
<ci> F6Pcyt </ci>
|
1192
|
+
<ci> UDPGcyt </ci>
|
1193
|
+
</apply>
|
1194
|
+
<apply>
|
1195
|
+
<divide/>
|
1196
|
+
<apply>
|
1197
|
+
<times/>
|
1198
|
+
<ci> UDPcyt </ci>
|
1199
|
+
<ci> Pcyt </ci>
|
1200
|
+
</apply>
|
1201
|
+
<ci> KeqSPSSPP </ci>
|
1202
|
+
</apply>
|
1203
|
+
</apply>
|
1204
|
+
</apply>
|
1205
|
+
<apply>
|
1206
|
+
<plus/>
|
1207
|
+
<apply>
|
1208
|
+
<times/>
|
1209
|
+
<ci> KmF6PSPSSPP </ci>
|
1210
|
+
<ci> KmUDPGSPSSPP </ci>
|
1211
|
+
</apply>
|
1212
|
+
<apply>
|
1213
|
+
<times/>
|
1214
|
+
<ci> F6Pcyt </ci>
|
1215
|
+
<ci> UDPGcyt </ci>
|
1216
|
+
</apply>
|
1217
|
+
<apply>
|
1218
|
+
<divide/>
|
1219
|
+
<apply>
|
1220
|
+
<times/>
|
1221
|
+
<ci> UDPcyt </ci>
|
1222
|
+
<ci> Pcyt </ci>
|
1223
|
+
<ci> VratioSPSSPP </ci>
|
1224
|
+
</apply>
|
1225
|
+
<ci> KeqSPSSPP </ci>
|
1226
|
+
</apply>
|
1227
|
+
<apply>
|
1228
|
+
<divide/>
|
1229
|
+
<apply>
|
1230
|
+
<times/>
|
1231
|
+
<ci> Sucrose </ci>
|
1232
|
+
<ci> KmF6PSPSSPP </ci>
|
1233
|
+
<ci> KmUDPGSPSSPP </ci>
|
1234
|
+
</apply>
|
1235
|
+
<ci> KiSucroseSPSSPP </ci>
|
1236
|
+
</apply>
|
1237
|
+
</apply>
|
1238
|
+
</apply>
|
1239
|
+
</math>
|
1240
|
+
</kineticLaw>
|
1241
|
+
</reaction>
|
1242
|
+
<reaction id="vSSynth" name="vSSynth">
|
1243
|
+
<listOfReactants>
|
1244
|
+
<speciesReference species="Fructose"/>
|
1245
|
+
<speciesReference species="UDPGcyt"/>
|
1246
|
+
</listOfReactants>
|
1247
|
+
<listOfProducts>
|
1248
|
+
<speciesReference species="Sucrose"/>
|
1249
|
+
<speciesReference species="UDPcyt"/>
|
1250
|
+
</listOfProducts>
|
1251
|
+
<listOfModifiers>
|
1252
|
+
<modifierSpeciesReference species="Glucosecyt"/>
|
1253
|
+
</listOfModifiers>
|
1254
|
+
<kineticLaw>
|
1255
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
1256
|
+
<apply>
|
1257
|
+
<divide/>
|
1258
|
+
<apply>
|
1259
|
+
<divide/>
|
1260
|
+
<apply>
|
1261
|
+
<times/>
|
1262
|
+
<ci> VmaxSSynth </ci>
|
1263
|
+
<apply>
|
1264
|
+
<divide/>
|
1265
|
+
<apply>
|
1266
|
+
<times/>
|
1267
|
+
<ci> Fructose </ci>
|
1268
|
+
<ci> UDPGcyt </ci>
|
1269
|
+
</apply>
|
1270
|
+
<apply>
|
1271
|
+
<times/>
|
1272
|
+
<ci> KmSSynthFructose </ci>
|
1273
|
+
<ci> KmSSynthUDPG </ci>
|
1274
|
+
</apply>
|
1275
|
+
</apply>
|
1276
|
+
<apply>
|
1277
|
+
<minus/>
|
1278
|
+
<cn type="integer"> 1 </cn>
|
1279
|
+
<apply>
|
1280
|
+
<divide/>
|
1281
|
+
<apply>
|
1282
|
+
<divide/>
|
1283
|
+
<apply>
|
1284
|
+
<divide/>
|
1285
|
+
<apply>
|
1286
|
+
<times/>
|
1287
|
+
<ci> Sucrose </ci>
|
1288
|
+
<ci> UDPcyt </ci>
|
1289
|
+
</apply>
|
1290
|
+
<ci> Fructose </ci>
|
1291
|
+
</apply>
|
1292
|
+
<ci> UDPGcyt </ci>
|
1293
|
+
</apply>
|
1294
|
+
<ci> KeqSSynth </ci>
|
1295
|
+
</apply>
|
1296
|
+
</apply>
|
1297
|
+
</apply>
|
1298
|
+
<apply>
|
1299
|
+
<plus/>
|
1300
|
+
<cn type="integer"> 1 </cn>
|
1301
|
+
<apply>
|
1302
|
+
<divide/>
|
1303
|
+
<apply>
|
1304
|
+
<times/>
|
1305
|
+
<ci> Fructose </ci>
|
1306
|
+
<ci> UDPGcyt </ci>
|
1307
|
+
</apply>
|
1308
|
+
<apply>
|
1309
|
+
<times/>
|
1310
|
+
<ci> KmSSynthFructose </ci>
|
1311
|
+
<ci> KmSSynthUDPG </ci>
|
1312
|
+
</apply>
|
1313
|
+
</apply>
|
1314
|
+
<apply>
|
1315
|
+
<divide/>
|
1316
|
+
<apply>
|
1317
|
+
<times/>
|
1318
|
+
<ci> Sucrose </ci>
|
1319
|
+
<ci> UDPcyt </ci>
|
1320
|
+
</apply>
|
1321
|
+
<apply>
|
1322
|
+
<times/>
|
1323
|
+
<ci> KmSSynthSucrose </ci>
|
1324
|
+
<ci> KmSSynthUDP </ci>
|
1325
|
+
</apply>
|
1326
|
+
</apply>
|
1327
|
+
</apply>
|
1328
|
+
</apply>
|
1329
|
+
<apply>
|
1330
|
+
<plus/>
|
1331
|
+
<cn type="integer"> 1 </cn>
|
1332
|
+
<apply>
|
1333
|
+
<divide/>
|
1334
|
+
<ci> Glucosecyt </ci>
|
1335
|
+
<ci> KiSSynthGlucose </ci>
|
1336
|
+
</apply>
|
1337
|
+
</apply>
|
1338
|
+
</apply>
|
1339
|
+
</math>
|
1340
|
+
</kineticLaw>
|
1341
|
+
</reaction>
|
1342
|
+
<reaction id="vSucUpt" name="vSucUpt">
|
1343
|
+
<listOfReactants>
|
1344
|
+
<speciesReference species="xsucrose"/>
|
1345
|
+
</listOfReactants>
|
1346
|
+
<listOfProducts>
|
1347
|
+
<speciesReference species="Sucrose"/>
|
1348
|
+
</listOfProducts>
|
1349
|
+
<kineticLaw>
|
1350
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
1351
|
+
<apply>
|
1352
|
+
<times/>
|
1353
|
+
<ci> VSucUpt </ci>
|
1354
|
+
<apply>
|
1355
|
+
<minus/>
|
1356
|
+
<apply>
|
1357
|
+
<times/>
|
1358
|
+
<ci> kforwardSucUpt </ci>
|
1359
|
+
<ci> xsucrose </ci>
|
1360
|
+
</apply>
|
1361
|
+
<apply>
|
1362
|
+
<times/>
|
1363
|
+
<ci> kbackwardSucUpt </ci>
|
1364
|
+
<ci> Sucrose </ci>
|
1365
|
+
</apply>
|
1366
|
+
</apply>
|
1367
|
+
</apply>
|
1368
|
+
</math>
|
1369
|
+
</kineticLaw>
|
1370
|
+
</reaction>
|
1371
|
+
<reaction id="vinv" name="vinv">
|
1372
|
+
<listOfReactants>
|
1373
|
+
<speciesReference species="Sucrose"/>
|
1374
|
+
</listOfReactants>
|
1375
|
+
<listOfProducts>
|
1376
|
+
<speciesReference species="Fructose"/>
|
1377
|
+
<speciesReference species="Glucosecyt"/>
|
1378
|
+
</listOfProducts>
|
1379
|
+
<kineticLaw>
|
1380
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
1381
|
+
<apply>
|
1382
|
+
<divide/>
|
1383
|
+
<apply>
|
1384
|
+
<times/>
|
1385
|
+
<ci> Vmaxinv </ci>
|
1386
|
+
<apply>
|
1387
|
+
<divide/>
|
1388
|
+
<ci> Sucrose </ci>
|
1389
|
+
<ci> KmSucroseinv </ci>
|
1390
|
+
</apply>
|
1391
|
+
</apply>
|
1392
|
+
<apply>
|
1393
|
+
<times/>
|
1394
|
+
<apply>
|
1395
|
+
<plus/>
|
1396
|
+
<cn type="integer"> 1 </cn>
|
1397
|
+
<apply>
|
1398
|
+
<divide/>
|
1399
|
+
<ci> Sucrose </ci>
|
1400
|
+
<ci> KmSucroseinv </ci>
|
1401
|
+
</apply>
|
1402
|
+
<apply>
|
1403
|
+
<divide/>
|
1404
|
+
<ci> Fructose </ci>
|
1405
|
+
<ci> KiFructoseinv </ci>
|
1406
|
+
</apply>
|
1407
|
+
</apply>
|
1408
|
+
<apply>
|
1409
|
+
<plus/>
|
1410
|
+
<cn type="integer"> 1 </cn>
|
1411
|
+
<apply>
|
1412
|
+
<divide/>
|
1413
|
+
<ci> Glucosecyt </ci>
|
1414
|
+
<ci> KiGlucoseinv </ci>
|
1415
|
+
</apply>
|
1416
|
+
</apply>
|
1417
|
+
</apply>
|
1418
|
+
</apply>
|
1419
|
+
</math>
|
1420
|
+
</kineticLaw>
|
1421
|
+
</reaction>
|
1422
|
+
<reaction id="vFK" name="vFK">
|
1423
|
+
<listOfReactants>
|
1424
|
+
<speciesReference species="Fructose"/>
|
1425
|
+
<speciesReference species="ATPcyt"/>
|
1426
|
+
</listOfReactants>
|
1427
|
+
<listOfProducts>
|
1428
|
+
<speciesReference species="F6Pcyt"/>
|
1429
|
+
<speciesReference species="ADPcyt"/>
|
1430
|
+
</listOfProducts>
|
1431
|
+
<kineticLaw>
|
1432
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
1433
|
+
<apply>
|
1434
|
+
<divide/>
|
1435
|
+
<apply>
|
1436
|
+
<times/>
|
1437
|
+
<ci> VmaxFK </ci>
|
1438
|
+
<apply>
|
1439
|
+
<divide/>
|
1440
|
+
<apply>
|
1441
|
+
<times/>
|
1442
|
+
<ci> Fructose </ci>
|
1443
|
+
<ci> ATPcyt </ci>
|
1444
|
+
</apply>
|
1445
|
+
<apply>
|
1446
|
+
<times/>
|
1447
|
+
<ci> KmFructoseFK </ci>
|
1448
|
+
<ci> KmATPFK </ci>
|
1449
|
+
</apply>
|
1450
|
+
</apply>
|
1451
|
+
</apply>
|
1452
|
+
<apply>
|
1453
|
+
<times/>
|
1454
|
+
<apply>
|
1455
|
+
<plus/>
|
1456
|
+
<cn type="integer"> 1 </cn>
|
1457
|
+
<apply>
|
1458
|
+
<divide/>
|
1459
|
+
<ci> Fructose </ci>
|
1460
|
+
<ci> KmFructoseFK </ci>
|
1461
|
+
</apply>
|
1462
|
+
</apply>
|
1463
|
+
<apply>
|
1464
|
+
<plus/>
|
1465
|
+
<cn type="integer"> 1 </cn>
|
1466
|
+
<apply>
|
1467
|
+
<divide/>
|
1468
|
+
<ci> Fructose </ci>
|
1469
|
+
<ci> KiFructoseFK </ci>
|
1470
|
+
</apply>
|
1471
|
+
</apply>
|
1472
|
+
<apply>
|
1473
|
+
<plus/>
|
1474
|
+
<cn type="integer"> 1 </cn>
|
1475
|
+
<apply>
|
1476
|
+
<divide/>
|
1477
|
+
<ci> F6Pcyt </ci>
|
1478
|
+
<ci> KmF6PFK </ci>
|
1479
|
+
</apply>
|
1480
|
+
</apply>
|
1481
|
+
<apply>
|
1482
|
+
<plus/>
|
1483
|
+
<cn type="integer"> 1 </cn>
|
1484
|
+
<apply>
|
1485
|
+
<divide/>
|
1486
|
+
<ci> ATPcyt </ci>
|
1487
|
+
<ci> KmATPFK </ci>
|
1488
|
+
</apply>
|
1489
|
+
<apply>
|
1490
|
+
<divide/>
|
1491
|
+
<ci> Fructose </ci>
|
1492
|
+
<ci> KiFructoseFK </ci>
|
1493
|
+
</apply>
|
1494
|
+
<apply>
|
1495
|
+
<divide/>
|
1496
|
+
<ci> ADPcyt </ci>
|
1497
|
+
<ci> KmADPFK </ci>
|
1498
|
+
</apply>
|
1499
|
+
</apply>
|
1500
|
+
</apply>
|
1501
|
+
</apply>
|
1502
|
+
</math>
|
1503
|
+
</kineticLaw>
|
1504
|
+
</reaction>
|
1505
|
+
<reaction id="vHK" name="vHK">
|
1506
|
+
<listOfReactants>
|
1507
|
+
<speciesReference species="Glucosecyt"/>
|
1508
|
+
<speciesReference species="ATPcyt"/>
|
1509
|
+
</listOfReactants>
|
1510
|
+
<listOfProducts>
|
1511
|
+
<speciesReference species="G6Pcyt"/>
|
1512
|
+
<speciesReference species="ADPcyt"/>
|
1513
|
+
</listOfProducts>
|
1514
|
+
<listOfModifiers>
|
1515
|
+
<modifierSpeciesReference species="Fructose"/>
|
1516
|
+
<modifierSpeciesReference species="Fructose"/>
|
1517
|
+
</listOfModifiers>
|
1518
|
+
<kineticLaw>
|
1519
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
1520
|
+
<apply>
|
1521
|
+
<plus/>
|
1522
|
+
<apply>
|
1523
|
+
<divide/>
|
1524
|
+
<apply>
|
1525
|
+
<times/>
|
1526
|
+
<apply>
|
1527
|
+
<divide/>
|
1528
|
+
<ci> VmaxGK </ci>
|
1529
|
+
<cn type="integer"> 2 </cn>
|
1530
|
+
</apply>
|
1531
|
+
<apply>
|
1532
|
+
<divide/>
|
1533
|
+
<apply>
|
1534
|
+
<times/>
|
1535
|
+
<ci> Glucosecyt </ci>
|
1536
|
+
<ci> ATPcyt </ci>
|
1537
|
+
</apply>
|
1538
|
+
<apply>
|
1539
|
+
<times/>
|
1540
|
+
<ci> KmGlucoseHK1 </ci>
|
1541
|
+
<ci> KmATPHK1 </ci>
|
1542
|
+
</apply>
|
1543
|
+
</apply>
|
1544
|
+
</apply>
|
1545
|
+
<apply>
|
1546
|
+
<times/>
|
1547
|
+
<apply>
|
1548
|
+
<plus/>
|
1549
|
+
<cn type="integer"> 1 </cn>
|
1550
|
+
<apply>
|
1551
|
+
<divide/>
|
1552
|
+
<ci> Glucosecyt </ci>
|
1553
|
+
<ci> KmGlucoseHK1 </ci>
|
1554
|
+
</apply>
|
1555
|
+
<apply>
|
1556
|
+
<divide/>
|
1557
|
+
<ci> Fructose </ci>
|
1558
|
+
<ci> KmFructoseHK1 </ci>
|
1559
|
+
</apply>
|
1560
|
+
</apply>
|
1561
|
+
<apply>
|
1562
|
+
<plus/>
|
1563
|
+
<cn type="integer"> 1 </cn>
|
1564
|
+
<apply>
|
1565
|
+
<divide/>
|
1566
|
+
<ci> ATPcyt </ci>
|
1567
|
+
<ci> KmATPHK1 </ci>
|
1568
|
+
</apply>
|
1569
|
+
<apply>
|
1570
|
+
<divide/>
|
1571
|
+
<ci> ADPcyt </ci>
|
1572
|
+
<ci> KiADPHK1 </ci>
|
1573
|
+
</apply>
|
1574
|
+
</apply>
|
1575
|
+
<apply>
|
1576
|
+
<plus/>
|
1577
|
+
<cn type="integer"> 1 </cn>
|
1578
|
+
<apply>
|
1579
|
+
<divide/>
|
1580
|
+
<ci> G6Pcyt </ci>
|
1581
|
+
<ci> KiG6PHK1 </ci>
|
1582
|
+
</apply>
|
1583
|
+
</apply>
|
1584
|
+
</apply>
|
1585
|
+
</apply>
|
1586
|
+
<apply>
|
1587
|
+
<divide/>
|
1588
|
+
<apply>
|
1589
|
+
<times/>
|
1590
|
+
<apply>
|
1591
|
+
<divide/>
|
1592
|
+
<ci> VmaxGK </ci>
|
1593
|
+
<cn type="integer"> 2 </cn>
|
1594
|
+
</apply>
|
1595
|
+
<apply>
|
1596
|
+
<divide/>
|
1597
|
+
<apply>
|
1598
|
+
<times/>
|
1599
|
+
<ci> Glucosecyt </ci>
|
1600
|
+
<ci> ATPcyt </ci>
|
1601
|
+
</apply>
|
1602
|
+
<apply>
|
1603
|
+
<times/>
|
1604
|
+
<ci> KmGlucoseHK2 </ci>
|
1605
|
+
<ci> KmATPHK2 </ci>
|
1606
|
+
</apply>
|
1607
|
+
</apply>
|
1608
|
+
</apply>
|
1609
|
+
<apply>
|
1610
|
+
<times/>
|
1611
|
+
<apply>
|
1612
|
+
<plus/>
|
1613
|
+
<cn type="integer"> 1 </cn>
|
1614
|
+
<apply>
|
1615
|
+
<divide/>
|
1616
|
+
<ci> Glucosecyt </ci>
|
1617
|
+
<ci> KmGlucoseHK2 </ci>
|
1618
|
+
</apply>
|
1619
|
+
<apply>
|
1620
|
+
<divide/>
|
1621
|
+
<ci> Fructose </ci>
|
1622
|
+
<ci> KmFructoseHK2 </ci>
|
1623
|
+
</apply>
|
1624
|
+
</apply>
|
1625
|
+
<apply>
|
1626
|
+
<plus/>
|
1627
|
+
<cn type="integer"> 1 </cn>
|
1628
|
+
<apply>
|
1629
|
+
<divide/>
|
1630
|
+
<ci> ATPcyt </ci>
|
1631
|
+
<ci> KmATPHK2 </ci>
|
1632
|
+
</apply>
|
1633
|
+
<apply>
|
1634
|
+
<divide/>
|
1635
|
+
<ci> ADPcyt </ci>
|
1636
|
+
<ci> KiADPHK2 </ci>
|
1637
|
+
</apply>
|
1638
|
+
</apply>
|
1639
|
+
</apply>
|
1640
|
+
</apply>
|
1641
|
+
</apply>
|
1642
|
+
</math>
|
1643
|
+
</kineticLaw>
|
1644
|
+
</reaction>
|
1645
|
+
<reaction id="vNDPK" name="vNDPK">
|
1646
|
+
<listOfReactants>
|
1647
|
+
<speciesReference species="ATPcyt"/>
|
1648
|
+
<speciesReference species="UDPcyt"/>
|
1649
|
+
</listOfReactants>
|
1650
|
+
<listOfProducts>
|
1651
|
+
<speciesReference species="ADPcyt"/>
|
1652
|
+
<speciesReference species="UTPcyt"/>
|
1653
|
+
</listOfProducts>
|
1654
|
+
<kineticLaw>
|
1655
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
1656
|
+
<apply>
|
1657
|
+
<times/>
|
1658
|
+
<ci> VNDPK </ci>
|
1659
|
+
<apply>
|
1660
|
+
<minus/>
|
1661
|
+
<apply>
|
1662
|
+
<times/>
|
1663
|
+
<ci> kforwardNDPK </ci>
|
1664
|
+
<ci> ATPcyt </ci>
|
1665
|
+
<ci> UDPcyt </ci>
|
1666
|
+
</apply>
|
1667
|
+
<apply>
|
1668
|
+
<times/>
|
1669
|
+
<ci> kbackwardNDPK </ci>
|
1670
|
+
<ci> ADPcyt </ci>
|
1671
|
+
<ci> UTPcyt </ci>
|
1672
|
+
</apply>
|
1673
|
+
</apply>
|
1674
|
+
</apply>
|
1675
|
+
</math>
|
1676
|
+
</kineticLaw>
|
1677
|
+
</reaction>
|
1678
|
+
<reaction id="vAT" name="vAT">
|
1679
|
+
<listOfReactants>
|
1680
|
+
<speciesReference species="ADPam"/>
|
1681
|
+
<speciesReference species="ATPcyt"/>
|
1682
|
+
</listOfReactants>
|
1683
|
+
<listOfProducts>
|
1684
|
+
<speciesReference species="ATPam"/>
|
1685
|
+
<speciesReference species="ADPcyt"/>
|
1686
|
+
</listOfProducts>
|
1687
|
+
<kineticLaw>
|
1688
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
1689
|
+
<apply>
|
1690
|
+
<times/>
|
1691
|
+
<ci> VAT </ci>
|
1692
|
+
<apply>
|
1693
|
+
<minus/>
|
1694
|
+
<apply>
|
1695
|
+
<times/>
|
1696
|
+
<ci> kforwardAT </ci>
|
1697
|
+
<ci> ATPcyt </ci>
|
1698
|
+
<ci> ADPam </ci>
|
1699
|
+
</apply>
|
1700
|
+
<apply>
|
1701
|
+
<times/>
|
1702
|
+
<ci> kbackwardAT </ci>
|
1703
|
+
<ci> ATPam </ci>
|
1704
|
+
<ci> ADPcyt </ci>
|
1705
|
+
</apply>
|
1706
|
+
</apply>
|
1707
|
+
</apply>
|
1708
|
+
</math>
|
1709
|
+
</kineticLaw>
|
1710
|
+
</reaction>
|
1711
|
+
<reaction id="vPexp" name="vPexp">
|
1712
|
+
<listOfReactants>
|
1713
|
+
<speciesReference species="Pam"/>
|
1714
|
+
</listOfReactants>
|
1715
|
+
<listOfProducts>
|
1716
|
+
<speciesReference species="Pcyt"/>
|
1717
|
+
</listOfProducts>
|
1718
|
+
<kineticLaw>
|
1719
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
1720
|
+
<apply>
|
1721
|
+
<times/>
|
1722
|
+
<ci> VPexp </ci>
|
1723
|
+
<apply>
|
1724
|
+
<minus/>
|
1725
|
+
<apply>
|
1726
|
+
<times/>
|
1727
|
+
<ci> kforwardPexp </ci>
|
1728
|
+
<ci> Pam </ci>
|
1729
|
+
</apply>
|
1730
|
+
<apply>
|
1731
|
+
<times/>
|
1732
|
+
<ci> kbackwardPexp </ci>
|
1733
|
+
<ci> Pcyt </ci>
|
1734
|
+
</apply>
|
1735
|
+
</apply>
|
1736
|
+
</apply>
|
1737
|
+
</math>
|
1738
|
+
</kineticLaw>
|
1739
|
+
</reaction>
|
1740
|
+
<reaction id="vATPcons" name="vATPcons">
|
1741
|
+
<listOfReactants>
|
1742
|
+
<speciesReference species="ATPcyt"/>
|
1743
|
+
</listOfReactants>
|
1744
|
+
<listOfProducts>
|
1745
|
+
<speciesReference species="ADPcyt"/>
|
1746
|
+
<speciesReference species="Pcyt"/>
|
1747
|
+
</listOfProducts>
|
1748
|
+
<kineticLaw>
|
1749
|
+
<math xmlns="http://www.w3.org/1998/Math/MathML">
|
1750
|
+
<apply>
|
1751
|
+
<times/>
|
1752
|
+
<ci> VATPcons </ci>
|
1753
|
+
<ci> kATPcons </ci>
|
1754
|
+
<apply>
|
1755
|
+
<divide/>
|
1756
|
+
<ci> ATPcyt </ci>
|
1757
|
+
<ci> ADPcyt </ci>
|
1758
|
+
</apply>
|
1759
|
+
</apply>
|
1760
|
+
</math>
|
1761
|
+
</kineticLaw>
|
1762
|
+
</reaction>
|
1763
|
+
</listOfReactions>
|
1764
|
+
</model></sbml>
|