bioroebe 0.12.24 → 0.13.31

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Files changed (503) hide show
  1. checksums.yaml +4 -4
  2. data/LICENSE.md +7 -8
  3. data/README.md +566 -354
  4. data/bin/all_positions_of_this_nucleotide +1 -1
  5. data/bin/aminoacid_frequencies +1 -1
  6. data/bin/automatically_rename_this_fasta_file +1 -1
  7. data/bin/base_composition +1 -1
  8. data/bin/batch_create_windows_executables +1 -1
  9. data/bin/bioroebe +12 -1
  10. data/bin/bioroebe_cat +7 -0
  11. data/bin/calculate_exponential_growth +7 -0
  12. data/bin/calculate_n50_value +1 -1
  13. data/bin/calculate_the_frequencies_of_this_species +7 -0
  14. data/bin/chunked_display +1 -1
  15. data/bin/codon_frequency +1 -1
  16. data/bin/codon_to_aminoacid +1 -1
  17. data/bin/colourize_this_fasta_sequence +1 -1
  18. data/bin/complementary_dna_strand +1 -1
  19. data/bin/complementary_rna_strand +1 -1
  20. data/bin/consensus_sequence +1 -1
  21. data/bin/dna_to_rna +1 -1
  22. data/bin/downcase_chunked_display +1 -1
  23. data/bin/download_this_pdb +1 -1
  24. data/bin/fasta_index +1 -1
  25. data/bin/fetch_data_from_uniprot +1 -1
  26. data/bin/filter_away_invalid_nucleotides +1 -1
  27. data/bin/find_substring +1 -1
  28. data/bin/input_as_dna +1 -1
  29. data/bin/is_palindrome +1 -1
  30. data/bin/leading_five_prime +1 -1
  31. data/bin/longest_ORF +1 -1
  32. data/bin/longest_substring +1 -1
  33. data/bin/open_reading_frames +1 -1
  34. data/bin/partner_nucleotide +1 -1
  35. data/bin/plain_palindrome +1 -1
  36. data/bin/random_dna_sequence +1 -1
  37. data/bin/random_sequence +1 -1
  38. data/bin/raw_hamming_distance +1 -1
  39. data/bin/return_longest_substring_via_LCS_algorithm +1 -1
  40. data/bin/reverse_sequence +1 -1
  41. data/bin/short_aminoacid_letter_from_long_aminoacid_name +1 -1
  42. data/bin/show_atomic_composition +1 -1
  43. data/bin/show_fasta_header +1 -1
  44. data/bin/show_nucleotide_sequence +1 -1
  45. data/bin/show_this_dna_sequence +1 -1
  46. data/bin/show_time_now +7 -0
  47. data/bin/sort_aminoacid_based_on_its_hydrophobicity +1 -1
  48. data/bin/strict_filter_away_invalid_aminoacids +1 -1
  49. data/{lib/bioroebe/base/reset.rb → bin/three_delimiter} +9 -6
  50. data/bin/three_to_one +1 -1
  51. data/bin/to_rna +1 -1
  52. data/bin/trailing_three_prime +1 -1
  53. data/bin/upcase_this_aminoacid_sequence_and_remove_numbers +1 -1
  54. data/bioroebe.gemspec +6 -7
  55. data/doc/README.gen +534 -322
  56. data/doc/blosum/blosum.md +4 -0
  57. data/doc/compatibility/BIO_PHP.md +20 -18
  58. data/doc/compatibility/README.md +2 -3
  59. data/doc/compatibility/emboss.md +5 -3
  60. data/doc/{extensive_usage_example.md → extensive_usage_example/extensive_usage_example.md} +4 -2
  61. data/doc/{instructions_for_the_taxonomy_subproject.md → instructions_for_the_taxonomy_subproject/instructions_for_the_taxonomy_subproject.md} +36 -33
  62. data/doc/{legacy_paths.md → legacy_paths/legacy_paths.md} +3 -3
  63. data/doc/statistics/statistics.md +12 -10
  64. data/doc/todo/bioroebe_GUI_todo.md +6 -1
  65. data/doc/todo/bioroebe_java_todo.md +3 -2
  66. data/doc/todo/bioroebe_todo.md +328 -310
  67. data/doc/{using_biomart.md → using_biomart/using_biomart.md} +7 -3
  68. data/lib/bioroebe/abstract/features.rb +0 -0
  69. data/lib/bioroebe/aminoacids/aminoacid_substitution.rb +1 -1
  70. data/lib/bioroebe/aminoacids/aminoacids_mass_table.rb +3 -1
  71. data/lib/bioroebe/aminoacids/codon_percentage.rb +18 -10
  72. data/lib/bioroebe/aminoacids/create_random_aminoacids.rb +5 -2
  73. data/lib/bioroebe/aminoacids/deduce_aminoacid_sequence.rb +90 -64
  74. data/lib/bioroebe/aminoacids/display_aminoacid_table.rb +1 -3
  75. data/lib/bioroebe/aminoacids/show_hydrophobicity.rb +2 -2
  76. data/lib/bioroebe/annotations/create_annotation_format.rb +2 -2
  77. data/lib/bioroebe/base/base.rb +101 -6
  78. data/lib/bioroebe/base/base_module/base_module.rb +9 -1
  79. data/lib/bioroebe/base/colours.rb +3 -0
  80. data/lib/bioroebe/base/colours_for_base/colours_for_base.rb +80 -44
  81. data/lib/bioroebe/base/commandline_application/README.md +1 -1
  82. data/lib/bioroebe/base/commandline_application/commandline_application.rb +661 -22
  83. data/lib/bioroebe/base/commandline_application/commandline_arguments.rb +2 -1
  84. data/lib/bioroebe/base/infer_the_namespace_module/infer_the_namespace_module.rb +37 -0
  85. data/lib/bioroebe/base/internal_hash_module/internal_hash_module.rb +1 -6
  86. data/lib/bioroebe/base/prototype/prototype.rb +155 -14
  87. data/lib/bioroebe/biomart/attribute.rb +1 -1
  88. data/lib/bioroebe/biomart/biomart.rb +8 -9
  89. data/lib/bioroebe/biomart/server.rb +1 -1
  90. data/lib/bioroebe/blosum/blosum.rb +2 -2
  91. data/lib/bioroebe/calculate/calculate_blosum_score.rb +5 -3
  92. data/lib/bioroebe/calculate/calculate_gc_content.rb +1 -1
  93. data/lib/bioroebe/calculate/calculate_levensthein_distance.rb +5 -3
  94. data/lib/bioroebe/calculate/calculate_melting_temperature.rb +2 -10
  95. data/lib/bioroebe/calculate/calculate_melting_temperature_for_more_than_thirteen_nucleotides.rb +6 -15
  96. data/lib/bioroebe/calculate/calculate_the_position_specific_scoring_matrix.rb +4 -2
  97. data/lib/bioroebe/cell/cell.rb +3 -2
  98. data/lib/bioroebe/cell/specialized_cells/B_cell.rb +60 -0
  99. data/lib/bioroebe/cell/specialized_cells/Macrophage.rb +60 -0
  100. data/lib/bioroebe/cell/specialized_cells/README.md +5 -0
  101. data/lib/bioroebe/cell/specialized_cells/T_cell.rb +60 -0
  102. data/lib/bioroebe/cleave_and_digest/cleave.rb +3 -1
  103. data/lib/bioroebe/cleave_and_digest/digestion.rb +1 -1
  104. data/lib/bioroebe/codon_tables/frequencies/10090_Mus_musculus.yml +93 -0
  105. data/lib/bioroebe/codon_tables/frequencies/107243_Thlaspi_caerulescens.yml +72 -0
  106. data/lib/bioroebe/codon_tables/frequencies/parse_frequency_table.rb +2 -2
  107. data/lib/bioroebe/codons/codon_table.rb +10 -2
  108. data/lib/bioroebe/codons/codons.rb +3 -3
  109. data/lib/bioroebe/codons/convert_this_codon_to_that_aminoacid.rb +18 -15
  110. data/lib/bioroebe/codons/determine_optimal_codons.rb +1 -1
  111. data/lib/bioroebe/codons/possible_codons_for_this_aminoacid.rb +4 -2
  112. data/lib/bioroebe/codons/show_codon_tables.rb +1 -1
  113. data/lib/bioroebe/codons/show_codon_usage.rb +1 -2
  114. data/lib/bioroebe/codons/show_this_codon_table.rb +2 -2
  115. data/lib/bioroebe/codons/start_codons.rb +7 -3
  116. data/lib/bioroebe/colours/colour_schemes/README.md +1 -1
  117. data/lib/bioroebe/colours/colour_schemes/array_available_colour_schemes.rb +3 -3
  118. data/lib/bioroebe/colours/colour_schemes/colour_scheme.rb +3 -3
  119. data/lib/bioroebe/colours/colour_schemes/colour_scheme_demo.rb +4 -3
  120. data/lib/bioroebe/colours/colour_schemes/helix.rb +3 -1
  121. data/lib/bioroebe/colours/colour_schemes/hydropathy.rb +3 -1
  122. data/lib/bioroebe/colours/colour_schemes/score.rb +13 -2
  123. data/lib/bioroebe/colours/colour_schemes/strand.rb +3 -1
  124. data/lib/bioroebe/colours/colour_schemes/turn.rb +3 -1
  125. data/lib/bioroebe/colours/colour_schemes/zappo.rb +1 -1
  126. data/lib/bioroebe/{toplevel_methods/colourize_related_methods.rb → colours/colourize_related_code.rb} +1 -3
  127. data/lib/bioroebe/colours/colourize_sequence.rb +3 -1
  128. data/lib/bioroebe/colours/colours.rb +172 -15
  129. data/lib/bioroebe/configuration/configuration.rb +1 -1
  130. data/lib/bioroebe/constants/GUIs.rb +2 -2
  131. data/lib/bioroebe/constants/constants.rb +1349 -0
  132. data/lib/bioroebe/conversions/convert_aminoacid_to_dna.rb +8 -13
  133. data/lib/bioroebe/conversions/dna_to_aminoacid_sequence.rb +9 -3
  134. data/lib/bioroebe/count/count_amount_of_aminoacids.rb +11 -10
  135. data/lib/bioroebe/count/count_amount_of_nucleotides.rb +1 -1
  136. data/lib/bioroebe/count/count_at.rb +2 -1
  137. data/lib/bioroebe/databases/download_taxonomy_database.rb +1 -1
  138. data/lib/bioroebe/dotplots/advanced_dotplot.rb +2 -2
  139. data/lib/bioroebe/electron_microscopy/coordinate_analyzer.rb +2 -2
  140. data/lib/bioroebe/electron_microscopy/fix_pos_file.rb +2 -2
  141. data/lib/bioroebe/electron_microscopy/flipy.rb +2 -2
  142. data/lib/bioroebe/electron_microscopy/generate_em2em_file.rb +3 -11
  143. data/lib/bioroebe/electron_microscopy/parse_coordinates.rb +6 -6
  144. data/lib/bioroebe/electron_microscopy/read_file_xmd.rb +6 -6
  145. data/lib/bioroebe/electron_microscopy/simple_star_file_generator.rb +2 -2
  146. data/lib/bioroebe/enzymes/has_this_restriction_enzyme.rb +1 -1
  147. data/lib/bioroebe/enzymes/restriction_enzyme.rb +1 -1
  148. data/lib/bioroebe/enzymes/restriction_enzymes/statistics.rb +4 -3
  149. data/lib/bioroebe/enzymes/restriction_enzymes_file.rb +1 -1
  150. data/lib/bioroebe/enzymes/return_sequence_that_is_cut_via_restriction_enzyme.rb +4 -3
  151. data/lib/bioroebe/enzymes/show_restriction_enzymes.rb +3 -3
  152. data/lib/bioroebe/ext/main.cpp +0 -1
  153. data/lib/bioroebe/fasta_and_fastq/autocorrect_the_name_of_this_fasta_file.rb +3 -3
  154. data/lib/bioroebe/fasta_and_fastq/compact_fasta_file/compact_fasta_file.rb +1 -1
  155. data/lib/bioroebe/fasta_and_fastq/display_how_many_fasta_entries_are_in_this_directory.rb +1 -1
  156. data/lib/bioroebe/fasta_and_fastq/download_fasta.rb +8 -14
  157. data/lib/bioroebe/fasta_and_fastq/fasta_defline/fasta_defline.rb +1 -1
  158. data/lib/bioroebe/fasta_and_fastq/fasta_to_yaml/fasta_to_yaml.rb +1 -1
  159. data/lib/bioroebe/fasta_and_fastq/fastq_format_explainer.rb +1 -1
  160. data/lib/bioroebe/fasta_and_fastq/length_modifier/length_modifier.rb +1 -1
  161. data/lib/bioroebe/fasta_and_fastq/parse_fasta/parse_fasta.rb +37 -11
  162. data/lib/bioroebe/fasta_and_fastq/parse_fastq/parse_fastq.rb +2 -2
  163. data/lib/bioroebe/fasta_and_fastq/return_fasta_subsection_of_this_file.rb +1 -1
  164. data/lib/bioroebe/fasta_and_fastq/show_fasta_headers.rb +5 -13
  165. data/lib/bioroebe/fasta_and_fastq/show_fasta_statistics.rb +1 -1
  166. data/lib/bioroebe/fasta_and_fastq/simplify_fasta_header/simplify_fasta_header.rb +1 -1
  167. data/lib/bioroebe/fasta_and_fastq/split_this_fasta_file_into_chromosomes/reset.rb +3 -6
  168. data/lib/bioroebe/fasta_and_fastq/split_this_fasta_file_into_chromosomes/split_this_fasta_file_into_chromosomes.rb +3 -3
  169. data/lib/bioroebe/genbank/genbank_flat_file_format_generator.rb +20 -11
  170. data/lib/bioroebe/genome/genome.rb +1 -1
  171. data/lib/bioroebe/genomes/genome_pattern.rb +17 -16
  172. data/lib/bioroebe/genomes/genome_retriever.rb +4 -2
  173. data/lib/bioroebe/gui/experimental/snapgene/snapgene.rb +10 -13
  174. data/lib/bioroebe/gui/universal_widgets/alignment/alignment.rb +557 -0
  175. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/aminoacid_composition/aminoacid_composition.rb +498 -198
  176. data/lib/bioroebe/gui/universal_widgets/anti_sense_strand/anti_sense_strand.rb +665 -0
  177. data/lib/bioroebe/gui/universal_widgets/blosum_matrix_viewer/blosum_matrix_viewer.rb +329 -0
  178. data/lib/bioroebe/gui/universal_widgets/calculate_cell_numbers_of_bacteria/calculate_cell_numbers_of_bacteria.rb +423 -0
  179. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/controller/controller.rb +170 -118
  180. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/dna_to_aminoacid_widget/dna_to_aminoacid_widget.rb +277 -215
  181. data/lib/bioroebe/gui/{shared_code/dna_to_reverse_complement_widget/dna_to_reverse_complement_widget_module.rb → universal_widgets/dna_to_reverse_complement_widget/dna_to_reverse_complement_widget.rb} +297 -107
  182. data/lib/bioroebe/gui/universal_widgets/fasta_table_widget/fasta_table_widget.rb +643 -0
  183. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/format_converter/format_converter.rb +236 -164
  184. data/lib/bioroebe/gui/universal_widgets/gene/gene.rb +278 -0
  185. data/lib/bioroebe/gui/universal_widgets/hamming_distance/hamming_distance.rb +646 -0
  186. data/lib/bioroebe/gui/{shared_code/levensthein_distance/levensthein_distance_module.rb → universal_widgets/levensthein_distance/levensthein_distance.rb} +313 -88
  187. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/nucleotide_analyser/nucleotide_analyser.rb +281 -189
  188. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/parse_pdb_file/parse_pdb_file.rb +265 -149
  189. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/primer_design_widget/primer_design_widget.rb +337 -263
  190. data/lib/bioroebe/gui/universal_widgets/protein_to_DNA/protein_to_DNA.rb +408 -0
  191. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/random_sequence/random_sequence.rb +245 -187
  192. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/restriction_enzymes/restriction_enzymes.rb +207 -137
  193. data/lib/bioroebe/gui/universal_widgets/shell/shell.rb +288 -0
  194. data/lib/bioroebe/gui/{gtk3/show_codon_table/misc.rb → universal_widgets/show_codon_table/show_codon_table.rb} +290 -110
  195. data/lib/bioroebe/gui/{shared_code/show_codon_usage/show_codon_usage_module.rb → universal_widgets/show_codon_usage/show_codon_usage.rb} +228 -47
  196. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/sizeseq/sizeseq.rb +151 -69
  197. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/three_to_one/three_to_one.rb +190 -127
  198. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/www_finder/www_finder.rb +211 -152
  199. data/lib/bioroebe/images/images.html +953 -1170
  200. data/lib/bioroebe/images/misc/README.md +6 -0
  201. data/lib/bioroebe/images/misc/activation.avif +0 -0
  202. data/lib/bioroebe/images/misc/inhibition.avif +0 -0
  203. data/lib/bioroebe/images/misc/small_virus_logo.avif +0 -0
  204. data/lib/bioroebe/{constants/base_directory.rb → log_directory/log_directory.rb} +79 -59
  205. data/lib/bioroebe/matplotlib/matplotlib_generator.rb +1 -1
  206. data/lib/bioroebe/misc/quiz/three_letter_to_aminoacid.rb +1 -1
  207. data/lib/bioroebe/misc/ruler.rb +5 -5
  208. data/lib/bioroebe/misc/useful_formulas.rb +3 -3
  209. data/lib/bioroebe/ncbi/efetch.rb +1 -2
  210. data/lib/bioroebe/ngs/phred_quality_score_table.rb +3 -3
  211. data/lib/bioroebe/nucleotides/complementary_dna_strand.rb +3 -6
  212. data/lib/bioroebe/nucleotides/molecular_weight_of_nucleotides.rb +3 -3
  213. data/lib/bioroebe/nucleotides/most_likely_nucleotide_sequence_for_this_aminoacid_sequence.rb +6 -10
  214. data/lib/bioroebe/nucleotides/{show_nucleotide_sequence.rb → show_nucleotide_sequence/show_nucleotide_sequence.rb} +377 -255
  215. data/lib/bioroebe/palindromes/palindrome_2D_structure.rb +1 -1
  216. data/lib/bioroebe/palindromes/palindrome_finder.rb +1 -1
  217. data/lib/bioroebe/palindromes/palindrome_generator.rb +2 -10
  218. data/lib/bioroebe/parsers/biolang_parser.rb +1 -1
  219. data/lib/bioroebe/parsers/blosum_parser.rb +14 -19
  220. data/lib/bioroebe/parsers/genbank_parser.rb +2 -6
  221. data/lib/bioroebe/parsers/gff.rb +9 -9
  222. data/lib/bioroebe/parsers/parse_embl.rb +2 -6
  223. data/lib/bioroebe/parsers/stride_parser.rb +4 -12
  224. data/lib/bioroebe/patterns/analyse_glycosylation_pattern.rb +2 -2
  225. data/lib/bioroebe/patterns/is_this_sequence_a_EGF2_pattern.rb +6 -3
  226. data/lib/bioroebe/patterns/profile_pattern.rb +2 -2
  227. data/lib/bioroebe/patterns/rgg_scanner.rb +4 -2
  228. data/lib/bioroebe/{protein_structure → pdb_and_protein_structure}/alpha_helix.rb +2 -2
  229. data/lib/bioroebe/{pdb → pdb_and_protein_structure}/download_this_pdb.rb +2 -3
  230. data/lib/bioroebe/{pdb → pdb_and_protein_structure}/fetch_fasta_sequence_from_pdb.rb +4 -4
  231. data/lib/bioroebe/{protein_structure → pdb_and_protein_structure}/helical_wheel.rb +2 -2
  232. data/lib/bioroebe/{pdb → pdb_and_protein_structure}/parse_mmCIF_file.rb +1 -1
  233. data/lib/bioroebe/{pdb → pdb_and_protein_structure}/parse_pdb_file.rb +3 -3
  234. data/lib/bioroebe/{pdb → pdb_and_protein_structure}/report_secondary_structures_from_this_pdb_file.rb +3 -3
  235. data/lib/bioroebe/project/project.rb +3 -1
  236. data/lib/bioroebe/raw_sequence/README.md +8 -8
  237. data/lib/bioroebe/raw_sequence/raw_sequence.rb +11 -2
  238. data/lib/bioroebe/regexes/regexes.rb +1 -2
  239. data/lib/bioroebe/requires/commandline_application.rb +3 -1
  240. data/lib/bioroebe/requires/require_all_pdb_files.rb +1 -1
  241. data/lib/bioroebe/requires/require_all_taxonomy_files.rb +1 -1
  242. data/lib/bioroebe/requires/require_all_utility_scripts_files.rb +10 -0
  243. data/lib/bioroebe/requires/require_colours.rb +1 -1
  244. data/lib/bioroebe/requires/require_the_bioroebe_project.rb +5 -7
  245. data/lib/bioroebe/requires/require_the_bioroebe_sinatra_components.rb +1 -1
  246. data/lib/bioroebe/requires/require_the_constants.rb +2 -14
  247. data/lib/bioroebe/requires/require_yaml.rb +7 -5
  248. data/lib/bioroebe/sequence/alignment.rb +1 -1
  249. data/lib/bioroebe/sequence/dna.rb +4 -2
  250. data/lib/bioroebe/sequence/nucleotide_module/nucleotide_module.rb +22 -8
  251. data/lib/bioroebe/sequence/protein.rb +2 -2
  252. data/lib/bioroebe/sequence/reverse_complement.rb +3 -3
  253. data/lib/bioroebe/sequence/rna.rb +9 -8
  254. data/lib/bioroebe/sequence/sequence.rb +3 -3
  255. data/lib/bioroebe/shell/configuration/additionally_set_xorg_buffer.yml +0 -0
  256. data/lib/bioroebe/shell/configuration/may_we_show_the_startup_information.yml +0 -0
  257. data/lib/bioroebe/shell/configuration/upcase_nucleotides.yml +0 -0
  258. data/lib/bioroebe/shell/configuration/use_silent_startup.yml +1 -1
  259. data/lib/bioroebe/shell/help/class.rb +68 -19
  260. data/lib/bioroebe/shell/menu.rb +5244 -5322
  261. data/lib/bioroebe/shell/{readline/readline.rb → readline.rb} +1 -3
  262. data/lib/bioroebe/shell/shell.rb +11240 -453
  263. data/lib/bioroebe/siRNA/siRNA.rb +3 -3
  264. data/lib/bioroebe/{gui/shared_code/blosum_matrix_viewer/blosum_matrix_viewer_module.rb → sinatra/sinatra_interface.rb} +28 -19
  265. data/lib/bioroebe/{www/sinatra/sinatra.rb → sinatra/sinatra_wrapper.rb} +731 -754
  266. data/lib/bioroebe/string_matching/find_longest_substring.rb +2 -10
  267. data/lib/bioroebe/string_matching/find_longest_substring_via_LCS_algorithm.rb +4 -14
  268. data/lib/bioroebe/string_matching/hamming_distance.rb +11 -10
  269. data/lib/bioroebe/string_matching/levensthein.rb +5 -17
  270. data/lib/bioroebe/string_matching/simple_string_comparer.rb +48 -4
  271. data/lib/bioroebe/string_matching/smith_waterman.rb +11 -6
  272. data/lib/bioroebe/svg/glyph.rb +4 -1
  273. data/lib/bioroebe/svg/mini_feature.rb +1 -1
  274. data/lib/bioroebe/svg/page.rb +18 -7
  275. data/lib/bioroebe/svg/svgee.rb +22 -13
  276. data/lib/bioroebe/svg/track.rb +20 -4
  277. data/lib/bioroebe/taxonomy/chart.rb +2 -2
  278. data/lib/bioroebe/taxonomy/class_methods.rb +5 -6
  279. data/lib/bioroebe/taxonomy/constants.rb +1 -1
  280. data/lib/bioroebe/taxonomy/info/info.rb +1 -1
  281. data/lib/bioroebe/taxonomy/info/is_dna.rb +1 -1
  282. data/lib/bioroebe/taxonomy/interactive.rb +1 -2
  283. data/lib/bioroebe/taxonomy/menu.rb +1 -1
  284. data/lib/bioroebe/taxonomy/node.rb +1 -1
  285. data/lib/bioroebe/taxonomy/parse_fasta.rb +4 -2
  286. data/lib/bioroebe/taxonomy/shared.rb +5 -4
  287. data/lib/bioroebe/taxonomy/taxonomy.rb +2 -4
  288. data/lib/bioroebe/toplevel_methods/fasta_and_fastq.rb +3 -45
  289. data/lib/bioroebe/toplevel_methods/{is_on_roebe.rb → roebe.rb} +1 -11
  290. data/lib/bioroebe/toplevel_methods/taxonomy.rb +6 -12
  291. data/lib/bioroebe/toplevel_methods/toplevel_methods.rb +5568 -0
  292. data/lib/bioroebe/utility_scripts/align_open_reading_frames.rb +4 -3
  293. data/lib/bioroebe/utility_scripts/analyse_local_dataset.rb +2 -2
  294. data/lib/bioroebe/utility_scripts/check_for_mismatches/check_for_mismatches.rb +16 -9
  295. data/lib/bioroebe/utility_scripts/compacter/compacter.rb +4 -2
  296. data/lib/bioroebe/utility_scripts/compare_these_two_sequences_via_blosum.rb +119 -0
  297. data/lib/bioroebe/utility_scripts/compseq/compseq.rb +11 -9
  298. data/lib/bioroebe/utility_scripts/{consensus_sequence.rb → consensus_sequence/consensus_sequence.rb} +13 -4
  299. data/lib/bioroebe/utility_scripts/{create_batch_entrez_file.rb → create_batch_entrez_file/create_batch_entrez_file.rb} +5 -5
  300. data/lib/bioroebe/utility_scripts/{determine_antigenic_areas.rb → determine_antigenic_areas/determine_antigenic_areas.rb} +5 -5
  301. data/lib/bioroebe/utility_scripts/{determine_missing_nucleotides_percentage.rb → determine_missing_nucleotides_percentage/determine_missing_nucleotides_percentage.rb} +16 -15
  302. data/lib/bioroebe/utility_scripts/display_open_reading_frames/display_open_reading_frames.rb +7 -7
  303. data/lib/bioroebe/utility_scripts/display_open_reading_frames/misc.rb +1 -1
  304. data/lib/bioroebe/utility_scripts/display_open_reading_frames/report.rb +2 -0
  305. data/lib/bioroebe/utility_scripts/{dot_alignment.rb → dot_alignment/dot_alignment.rb} +3 -3
  306. data/lib/bioroebe/utility_scripts/{download_files_from_rebase.rb → download_files_from_rebase/download_files_from_rebase.rb} +5 -5
  307. data/lib/bioroebe/utility_scripts/fetch_data_from_uniprot/fetch_data_from_uniprot.rb +269 -0
  308. data/lib/bioroebe/utility_scripts/find_gene.rb +4 -2
  309. data/lib/bioroebe/utility_scripts/{mirror_repeat.rb → mirror_repeat/mirror_repeat.rb} +5 -5
  310. data/lib/bioroebe/utility_scripts/move_file_to_its_correct_location.rb +3 -3
  311. data/lib/bioroebe/utility_scripts/{parse_taxonomy.rb → parse_taxonomy/parse_taxonomy.rb} +15 -6
  312. data/lib/bioroebe/utility_scripts/{pathways.rb → pathways/pathways.rb} +4 -3
  313. data/lib/bioroebe/utility_scripts/{permutations.rb → permutations/permutations.rb} +3 -3
  314. data/lib/bioroebe/utility_scripts/punnet/punnet.rb +4 -2
  315. data/lib/bioroebe/utility_scripts/{show_this_dna_sequence.rb → show_this_dna_sequence/show_this_dna_sequence.rb} +1 -1
  316. data/lib/bioroebe/utility_scripts/showorf/showorf.rb +406 -10
  317. data/lib/bioroebe/version/version.rb +2 -2
  318. data/lib/bioroebe/viennarna/rnafold_wrapper.rb +5 -13
  319. data/lib/bioroebe/virus/individual_viruses/README.md +15 -0
  320. data/lib/bioroebe/virus/individual_viruses/tobacco_mosaic_virus.rb +40 -0
  321. data/lib/bioroebe/virus/virus.rb +76 -0
  322. data/lib/bioroebe/www/bioroebe.cgi +4 -3
  323. data/lib/bioroebe/www/embeddable_interface.rb +85 -49
  324. data/lib/bioroebe/yaml/agarose/agarose_concentrations.yml +6 -6
  325. data/lib/bioroebe/yaml/antisense/antisense.yml +2 -0
  326. data/lib/bioroebe/yaml/blosum/blosum50.yml +6 -0
  327. data/lib/bioroebe/yaml/blosum/blosum90.yml +2 -1
  328. data/lib/bioroebe/yaml/chromosomes/chromosome_numbers.yml +2 -2
  329. data/lib/bioroebe/yaml/configuration/temp_dir.yml +1 -1
  330. data/lib/bioroebe/yaml/consensus_sequences/consensus_sequences.yml +1 -0
  331. data/lib/bioroebe/yaml/enzymes/enzyme_classes.yml +7 -6
  332. data/lib/bioroebe/yaml/humans/human_chromosomes.yml +3 -3
  333. data/lib/bioroebe/yaml/mRNA/mRNA.yml +1 -5
  334. data/lib/bioroebe/yaml/nucleotides/abbreviations_for_nucleotides.yml +1 -0
  335. data/lib/bioroebe/yaml/nucleotides/nucleotide_density.yml +2 -1
  336. data/lib/bioroebe/yaml/promoters/35S.yml +3 -1
  337. data/lib/bioroebe/yaml/proteases/proteases.yml +3 -1
  338. data/lib/bioroebe/yaml/proteins/ubiquitin.yml +4 -1
  339. data/lib/bioroebe/yaml/restriction_enzymes/restriction_enzymes.yml +7 -7
  340. data/spec/testing_toplevel_method_editor.rb +1 -1
  341. data/spec/testing_toplevel_method_verbose.rb +1 -1
  342. data/test/testing_dna_to_rna_conversion.rb +1 -1
  343. metadata +127 -235
  344. data/doc/blosum.md +0 -5
  345. data/lib/bioroebe/base/commandline_application/aminoacids.rb +0 -33
  346. data/lib/bioroebe/base/commandline_application/directory.rb +0 -33
  347. data/lib/bioroebe/base/commandline_application/extract.rb +0 -22
  348. data/lib/bioroebe/base/commandline_application/misc.rb +0 -502
  349. data/lib/bioroebe/base/commandline_application/opn.rb +0 -47
  350. data/lib/bioroebe/base/commandline_application/reset.rb +0 -42
  351. data/lib/bioroebe/base/commandline_application/warnings.rb +0 -36
  352. data/lib/bioroebe/base/commandline_application/write_what_into.rb +0 -29
  353. data/lib/bioroebe/base/initialize.rb +0 -18
  354. data/lib/bioroebe/base/misc.rb +0 -129
  355. data/lib/bioroebe/base/namespace.rb +0 -16
  356. data/lib/bioroebe/base/prototype/e_and_ee.rb +0 -24
  357. data/lib/bioroebe/base/prototype/misc.rb +0 -114
  358. data/lib/bioroebe/base/prototype/mkdir.rb +0 -20
  359. data/lib/bioroebe/base/prototype/reset.rb +0 -36
  360. data/lib/bioroebe/colours/misc_colours.rb +0 -80
  361. data/lib/bioroebe/colours/rev.rb +0 -44
  362. data/lib/bioroebe/colours/sdir.rb +0 -21
  363. data/lib/bioroebe/colours/sfancy.rb +0 -21
  364. data/lib/bioroebe/colours/sfile.rb +0 -21
  365. data/lib/bioroebe/colours/simp.rb +0 -21
  366. data/lib/bioroebe/colours/swarn.rb +0 -29
  367. data/lib/bioroebe/constants/aminoacids_and_proteins.rb +0 -147
  368. data/lib/bioroebe/constants/carriage_return.rb +0 -14
  369. data/lib/bioroebe/constants/codon_tables.rb +0 -77
  370. data/lib/bioroebe/constants/database_constants.rb +0 -107
  371. data/lib/bioroebe/constants/files_and_directories.rb +0 -606
  372. data/lib/bioroebe/constants/misc.rb +0 -209
  373. data/lib/bioroebe/constants/newline.rb +0 -14
  374. data/lib/bioroebe/constants/nucleotides.rb +0 -121
  375. data/lib/bioroebe/constants/regex.rb +0 -28
  376. data/lib/bioroebe/constants/roebe.rb +0 -38
  377. data/lib/bioroebe/constants/row_terminator.rb +0 -16
  378. data/lib/bioroebe/constants/tabulator.rb +0 -14
  379. data/lib/bioroebe/constants/unicode.rb +0 -12
  380. data/lib/bioroebe/constants/urls.rb +0 -50
  381. data/lib/bioroebe/gui/gtk +0 -1
  382. data/lib/bioroebe/gui/gtk3/README.md +0 -2
  383. data/lib/bioroebe/gui/gtk3/alignment/alignment.rb +0 -306
  384. data/lib/bioroebe/gui/gtk3/anti_sense_strand/anti_sense_strand.rb +0 -29
  385. data/lib/bioroebe/gui/gtk3/blosum_matrix_viewer/blosum_matrix_viewer.rb +0 -195
  386. data/lib/bioroebe/gui/gtk3/calculate_cell_numbers_of_bacteria/calculate_cell_numbers_of_bacteria.rb +0 -105
  387. data/lib/bioroebe/gui/gtk3/dna_to_reverse_complement_widget/dna_to_reverse_complement_widget.rb +0 -188
  388. data/lib/bioroebe/gui/gtk3/fasta_table_widget/fasta_table_widget.rb +0 -322
  389. data/lib/bioroebe/gui/gtk3/gene/gene.rb +0 -181
  390. data/lib/bioroebe/gui/gtk3/hamming_distance/hamming_distance.rb +0 -383
  391. data/lib/bioroebe/gui/gtk3/levensthein_distance/levensthein_distance.rb +0 -174
  392. data/lib/bioroebe/gui/gtk3/protein_to_DNA/protein_to_DNA.rb +0 -181
  393. data/lib/bioroebe/gui/gtk3/show_codon_table/show_codon_table.rb +0 -101
  394. data/lib/bioroebe/gui/gtk3/show_codon_usage/show_codon_usage.rb +0 -145
  395. data/lib/bioroebe/gui/gtk3/three_to_one/title.rb +0 -23
  396. data/lib/bioroebe/gui/jruby/alignment/alignment.rb +0 -165
  397. data/lib/bioroebe/gui/jruby/aminoacid_composition/aminoacid_composition.rb +0 -166
  398. data/lib/bioroebe/gui/jruby/blosum_matrix_viewer/blosum_matrix_viewer.rb +0 -82
  399. data/lib/bioroebe/gui/libui/README.md +0 -4
  400. data/lib/bioroebe/gui/libui/alignment/alignment.rb +0 -116
  401. data/lib/bioroebe/gui/libui/blosum_matrix_viewer/blosum_matrix_viewer.rb +0 -112
  402. data/lib/bioroebe/gui/libui/calculate_cell_numbers_of_bacteria/calculate_cell_numbers_of_bacteria.rb +0 -60
  403. data/lib/bioroebe/gui/libui/controller/controller.rb +0 -116
  404. data/lib/bioroebe/gui/libui/dna_to_aminoacid_widget/dna_to_aminoacid_widget.rb +0 -161
  405. data/lib/bioroebe/gui/libui/dna_to_reverse_complement_widget/dna_to_reverse_complement_widget.rb +0 -76
  406. data/lib/bioroebe/gui/libui/hamming_distance/hamming_distance.rb +0 -135
  407. data/lib/bioroebe/gui/libui/levensthein_distance/levensthein_distance.rb +0 -118
  408. data/lib/bioroebe/gui/libui/protein_to_DNA/protein_to_DNA.rb +0 -115
  409. data/lib/bioroebe/gui/libui/random_sequence/random_sequence.rb +0 -190
  410. data/lib/bioroebe/gui/libui/show_codon_table/show_codon_table.rb +0 -134
  411. data/lib/bioroebe/gui/libui/show_codon_usage/show_codon_usage.rb +0 -89
  412. data/lib/bioroebe/gui/libui/three_to_one/three_to_one.rb +0 -113
  413. data/lib/bioroebe/gui/shared_code/alignment/alignment_module.rb +0 -102
  414. data/lib/bioroebe/gui/shared_code/aminoacid_composition/aminoacid_composition_module.rb +0 -94
  415. data/lib/bioroebe/gui/shared_code/calculate_cell_numbers_of_bacteria/calculate_cell_numbers_of_bacteria_module.rb +0 -216
  416. data/lib/bioroebe/gui/shared_code/protein_to_DNA/protein_to_DNA_module.rb +0 -192
  417. data/lib/bioroebe/gui/shared_code/show_codon_table/show_codon_table_module.rb +0 -72
  418. data/lib/bioroebe/gui/tk/aminoacid_composition/aminoacid_composition.rb +0 -206
  419. data/lib/bioroebe/gui/tk/blosum_matrix_viewer/blosum_matrix_viewer.rb +0 -140
  420. data/lib/bioroebe/gui/tk/hamming_distance/hamming_distance.rb +0 -262
  421. data/lib/bioroebe/gui/tk/levensthein_distance/levensthein_distance.rb +0 -243
  422. data/lib/bioroebe/gui/tk/three_to_one/three_to_one.rb +0 -199
  423. data/lib/bioroebe/gui/unified_widgets/anti_sense_strand/anti_sense_strand.rb +0 -519
  424. data/lib/bioroebe/shell/colours/colours.rb +0 -235
  425. data/lib/bioroebe/shell/help/help.rb +0 -25
  426. data/lib/bioroebe/shell/misc.rb +0 -10227
  427. data/lib/bioroebe/toplevel_methods/ad_hoc_task.rb +0 -56
  428. data/lib/bioroebe/toplevel_methods/aminoacids_and_proteins.rb +0 -722
  429. data/lib/bioroebe/toplevel_methods/atomic_composition.rb +0 -198
  430. data/lib/bioroebe/toplevel_methods/base_composition.rb +0 -121
  431. data/lib/bioroebe/toplevel_methods/blast.rb +0 -153
  432. data/lib/bioroebe/toplevel_methods/calculate_n50_value.rb +0 -57
  433. data/lib/bioroebe/toplevel_methods/cat.rb +0 -71
  434. data/lib/bioroebe/toplevel_methods/chunked_display.rb +0 -92
  435. data/lib/bioroebe/toplevel_methods/cliner.rb +0 -81
  436. data/lib/bioroebe/toplevel_methods/complement.rb +0 -58
  437. data/lib/bioroebe/toplevel_methods/convert_global_env.rb +0 -39
  438. data/lib/bioroebe/toplevel_methods/databases.rb +0 -73
  439. data/lib/bioroebe/toplevel_methods/delimiter.rb +0 -19
  440. data/lib/bioroebe/toplevel_methods/digest.rb +0 -81
  441. data/lib/bioroebe/toplevel_methods/download_and_fetch_data.rb +0 -146
  442. data/lib/bioroebe/toplevel_methods/e.rb +0 -20
  443. data/lib/bioroebe/toplevel_methods/editor.rb +0 -21
  444. data/lib/bioroebe/toplevel_methods/esystem.rb +0 -22
  445. data/lib/bioroebe/toplevel_methods/exponential_growth.rb +0 -74
  446. data/lib/bioroebe/toplevel_methods/extract.rb +0 -56
  447. data/lib/bioroebe/toplevel_methods/file_and_directory_related_actions.rb +0 -269
  448. data/lib/bioroebe/toplevel_methods/frequencies.rb +0 -99
  449. data/lib/bioroebe/toplevel_methods/hamming_distance.rb +0 -60
  450. data/lib/bioroebe/toplevel_methods/infer.rb +0 -66
  451. data/lib/bioroebe/toplevel_methods/leading_five_prime_and_trailing_three_prime.rb +0 -101
  452. data/lib/bioroebe/toplevel_methods/levensthein.rb +0 -63
  453. data/lib/bioroebe/toplevel_methods/log_directory.rb +0 -109
  454. data/lib/bioroebe/toplevel_methods/longest_common_substring.rb +0 -55
  455. data/lib/bioroebe/toplevel_methods/map_ncbi_entry_to_eutils_id.rb +0 -88
  456. data/lib/bioroebe/toplevel_methods/matches.rb +0 -259
  457. data/lib/bioroebe/toplevel_methods/misc.rb +0 -596
  458. data/lib/bioroebe/toplevel_methods/nucleotides.rb +0 -787
  459. data/lib/bioroebe/toplevel_methods/number_of_clones.rb +0 -63
  460. data/lib/bioroebe/toplevel_methods/open_in_browser.rb +0 -79
  461. data/lib/bioroebe/toplevel_methods/open_reading_frames.rb +0 -236
  462. data/lib/bioroebe/toplevel_methods/opn.rb +0 -34
  463. data/lib/bioroebe/toplevel_methods/palindromes.rb +0 -155
  464. data/lib/bioroebe/toplevel_methods/parse.rb +0 -59
  465. data/lib/bioroebe/toplevel_methods/phred_error_probability.rb +0 -68
  466. data/lib/bioroebe/toplevel_methods/rds.rb +0 -24
  467. data/lib/bioroebe/toplevel_methods/remove.rb +0 -86
  468. data/lib/bioroebe/toplevel_methods/return_source_code_of_this_method.rb +0 -35
  469. data/lib/bioroebe/toplevel_methods/return_subsequence_based_on_indices.rb +0 -68
  470. data/lib/bioroebe/toplevel_methods/rna_splicing.rb +0 -73
  471. data/lib/bioroebe/toplevel_methods/rnalfold.rb +0 -69
  472. data/lib/bioroebe/toplevel_methods/searching_and_finding.rb +0 -116
  473. data/lib/bioroebe/toplevel_methods/shuffleseq.rb +0 -37
  474. data/lib/bioroebe/toplevel_methods/statistics.rb +0 -53
  475. data/lib/bioroebe/toplevel_methods/sum_of_odd_integers.rb +0 -62
  476. data/lib/bioroebe/toplevel_methods/three_delimiter.rb +0 -34
  477. data/lib/bioroebe/toplevel_methods/time_and_date.rb +0 -53
  478. data/lib/bioroebe/toplevel_methods/to_camelcase.rb +0 -31
  479. data/lib/bioroebe/toplevel_methods/truncate.rb +0 -48
  480. data/lib/bioroebe/toplevel_methods/url.rb +0 -36
  481. data/lib/bioroebe/toplevel_methods/verbose.rb +0 -59
  482. data/lib/bioroebe/utility_scripts/showorf/constants.rb +0 -31
  483. data/lib/bioroebe/utility_scripts/showorf/help.rb +0 -33
  484. data/lib/bioroebe/utility_scripts/showorf/initialize.rb +0 -52
  485. data/lib/bioroebe/utility_scripts/showorf/menu.rb +0 -68
  486. data/lib/bioroebe/utility_scripts/showorf/reset.rb +0 -36
  487. data/lib/bioroebe/utility_scripts/showorf/run.rb +0 -152
  488. data/lib/bioroebe/utility_scripts/showorf/show.rb +0 -97
  489. /data/doc/{german_names_for_the_aminoacids.md → german_names_for_the_aminoacids/german_names_for_the_aminoacids.md} +0 -0
  490. /data/doc/{pdb_ATOM_entry.md → pdb_ATOM_entry/pdb_ATOM_entry.md} +0 -0
  491. /data/doc/{resources.md → resources/resources.md} +0 -0
  492. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/aminoacid_composition/customized_dialog.rb +0 -0
  493. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/anti_sense_strand/anti_sense_strand.config +0 -0
  494. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/calculate_cell_numbers_of_bacteria/calculate_cell_numbers_of_bacteria.config +0 -0
  495. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/dna_to_reverse_complement_widget/dna_to_reverse_complement_widget.config +0 -0
  496. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/hamming_distance/hamming_distance.config +0 -0
  497. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/levensthein_distance/levensthein_distance.config +0 -0
  498. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/protein_to_DNA/protein_to_DNA.config +0 -0
  499. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/restriction_enzymes/restriction_enzymes.config +0 -0
  500. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/www_finder/www_finder.config +0 -0
  501. /data/lib/bioroebe/yaml/{base_composition_of_dna.yml → base_composition_of_dna/base_composition_of_dna.yml} +0 -0
  502. /data/lib/bioroebe/yaml/{nuclear_localization_sequences.yml → nuclear_localization_sequences/nuclear_localization_sequences.yml} +0 -0
  503. /data/lib/bioroebe/yaml/{talens.yml → talens/talens.yml} +0 -0
@@ -26,7 +26,7 @@
26
26
  # require 'bioroebe/utility_scripts/align_open_reading_frames.rb'
27
27
  # Bioroebe::AlignOpenReadingFrames.new(ARGV)
28
28
  # =========================================================================== #
29
- require 'bioroebe/base/commandline_application/commandline_application.rb'
29
+ require 'bioroebe/requires/commandline_application.rb'
30
30
 
31
31
  module Bioroebe
32
32
 
@@ -34,6 +34,7 @@ class AlignOpenReadingFrames < ::Bioroebe::CommandlineApplication # === Bioroebe
34
34
 
35
35
  require 'bioroebe/regexes/regexes.rb'
36
36
  require 'bioroebe/codons/codons.rb'
37
+ require 'bioroebe/codons/start_codons.rb'
37
38
 
38
39
  # ========================================================================= #
39
40
  # === START_CODON
@@ -150,8 +151,8 @@ class AlignOpenReadingFrames < ::Bioroebe::CommandlineApplication # === Bioroebe
150
151
  # ========================================================================= #
151
152
  def report_that_no_ORF_has_been_found
152
153
  this_length = input?.size
153
- opnn; erev "No valid stop-codon has been found for the given input"
154
- opnn; erev "sequence of length #{sfancy(this_length.to_s)}."
154
+ opnerev "No valid stop-codon has been found for the given input"
155
+ opnerev "sequence of length #{sfancy(this_length.to_s)}."
155
156
  end
156
157
 
157
158
  # ========================================================================= #
@@ -15,7 +15,7 @@
15
15
  # require 'bioroebe/utility_scripts/analyse_local_dataset.rb'
16
16
  # Bioroebe::AnalyseLocalDataset.new(ARGV)
17
17
  # =========================================================================== #
18
- require 'bioroebe/base/commandline_application/commandline_application.rb'
18
+ require 'bioroebe/requires/commandline_application.rb'
19
19
 
20
20
  module Bioroebe
21
21
 
@@ -108,7 +108,7 @@ class AnalyseLocalDataset < ::Bioroebe::CommandlineApplication # === Bioroebe::A
108
108
  # ========================================================================= #
109
109
  # === Bioroebe::AnalyseLocalDataset[]
110
110
  # ========================================================================= #
111
- def self.[](i)
111
+ def self.[](i = ARGV)
112
112
  new(i)
113
113
  end
114
114
 
@@ -13,7 +13,7 @@
13
13
  # =========================================================================== #
14
14
  # require 'bioroebe/utility_scripts/check_for_mismatches/check_for_mismatches.rb'
15
15
  # =========================================================================== #
16
- require 'bioroebe/base/commandline_application/commandline_application.rb'
16
+ require 'bioroebe/requires/commandline_application.rb'
17
17
 
18
18
  module Bioroebe
19
19
 
@@ -88,9 +88,9 @@ class CheckForMismatches < ::Bioroebe::CommandlineApplication # === Bioroebe::Ch
88
88
  # This method is to fetch user input.
89
89
  # ========================================================================= #
90
90
  def get_user_input
91
- opnn; erev 'Input your first sequence now:'
91
+ opnerev 'Input your first sequence now:'
92
92
  first_sequence = $stdin.gets.chomp
93
- opnn; erev 'Input your second sequence now:'
93
+ opnerev 'Input your second sequence now:'
94
94
  second_sequence = $stdin.gets.chomp
95
95
  set_data(first_sequence, second_sequence)
96
96
  end
@@ -103,11 +103,18 @@ class CheckForMismatches < ::Bioroebe::CommandlineApplication # === Bioroebe::Ch
103
103
  result = corresponding_nucleotide(@second_sequence[index])
104
104
  if character == result # then all is fine
105
105
  else # else this is not fine so we spit out the problem.
106
- @array_mismatches << [index+1, character]
106
+ array_mismatches? << [index+1, character]
107
107
  end
108
108
  }
109
109
  end
110
110
 
111
+ # ========================================================================= #
112
+ # === array_mismatches?
113
+ # ========================================================================= #
114
+ def array_mismatches?
115
+ @array_mismatches
116
+ end
117
+
111
118
  # ========================================================================= #
112
119
  # === corresponding_nucleotide
113
120
  # ========================================================================= #
@@ -157,14 +164,14 @@ class CheckForMismatches < ::Bioroebe::CommandlineApplication # === Bioroebe::Ch
157
164
  # === report_results (report tag)
158
165
  # ========================================================================= #
159
166
  def report_results
160
- mismatches = @array_mismatches
167
+ mismatches = array_mismatches?
161
168
  if mismatches.empty?
162
169
  e
163
170
  erev 'We found no mismatch.'
164
171
  e
165
172
  else
166
173
  e
167
- erev 'We found '+swarn('mismatches ')+rev+'at:'
174
+ erev swarn('Mismatches')+rev+' were found at the following locations:'
168
175
  e
169
176
  first_sequence = @first_sequence
170
177
  second_sequence = @second_sequence
@@ -175,7 +182,7 @@ class CheckForMismatches < ::Bioroebe::CommandlineApplication # === Bioroebe::Ch
175
182
  ', Nucleotide being: '+sfancy(character.to_s)
176
183
  }
177
184
  e
178
- @array_mismatches.reverse.each {|index, character|
185
+ array_mismatches?.reverse.each {|index, character|
179
186
  colourized_first_sequence[index-1,1] = send(COLOUR_TO_BE_USED_FOR_A_MISMATCH, character)+
180
187
  rev
181
188
  corresponding_character = colourized_second_sequence[index-1,1]
@@ -209,8 +216,8 @@ class CheckForMismatches < ::Bioroebe::CommandlineApplication # === Bioroebe::Ch
209
216
  # ========================================================================= #
210
217
  def run
211
218
  get_user_input if @obtain_user_input
212
- opnn; e rev+'We will now compare these two sequences'
213
- opnn; e rev+'for any potential mismatch(es).'
219
+ opnerev 'We will now compare these two sequences'
220
+ opnerev 'for any potential mismatch(es).'
214
221
  scan_for_mismatches
215
222
  report_results
216
223
  end
@@ -15,7 +15,7 @@
15
15
  # =========================================================================== #
16
16
  # require 'bioroebe/utility_scripts/compacter/compacter.rb'
17
17
  # =========================================================================== #
18
- require 'bioroebe/base/commandline_application/commandline_application.rb'
18
+ require 'bioroebe/requires/commandline_application.rb'
19
19
 
20
20
  module Bioroebe
21
21
 
@@ -97,6 +97,7 @@ class Compacter < ::Bioroebe::CommandlineApplication # === Bioroebe::Compacter
97
97
  # Usage example:
98
98
  #
99
99
  # compacter SPRR4_protein.fasta --retain-newlines
100
+ # compacter *eukin*.fasta --retain-newlines
100
101
  #
101
102
  # ===================================================================== #
102
103
  when /-?-?retain(-|_)?newlines/
@@ -117,7 +118,8 @@ class Compacter < ::Bioroebe::CommandlineApplication # === Bioroebe::Compacter
117
118
  # === show_help (help tag)
118
119
  # ========================================================================= #
119
120
  def show_help
120
- opnn { :no_newline }
121
+ opnn { :no_trailing }
122
+ e
121
123
  e
122
124
  e ' --retain-newlines # retain newlines, aka do not dump into a single line'
123
125
  e
@@ -0,0 +1,119 @@
1
+ #!/usr/bin/ruby -w
2
+ # Encoding: UTF-8
3
+ # frozen_string_literal: true
4
+ # =========================================================================== #
5
+ # === Bioroebe::CompareTheseTwoSequencesViaBlosum
6
+ #
7
+ # This class can be used to compare to sequences, towards a blosum file,
8
+ # such as BLOSUM50, and print out the score.
9
+ #
10
+ # Usage examples:
11
+ #
12
+ # Bioroebe::CompareTheseTwoSequencesViaBlosum.new(ARGV)
13
+ #
14
+ # =========================================================================== #
15
+ # require 'bioroebe/utility_scripts/compare_these_two_sequences_via_blosum.rb'
16
+ # Bioroebe::CompareTheseTwoSequencesViaBlosum.new(ARGV)
17
+ # =========================================================================== #
18
+ require 'bioroebe/requires/commandline_application.rb'
19
+
20
+ module Bioroebe
21
+
22
+ class CompareTheseTwoSequencesViaBlosum < ::Bioroebe::CommandlineApplication # === Bioroebe::CompareTheseTwoSequencesViaBlosum
23
+
24
+ # ========================================================================= #
25
+ # === USE_THIS_FILE
26
+ # ========================================================================= #
27
+ USE_THIS_FILE = '/home/x/Temp/bioroebe/blosum50.yml'
28
+
29
+ # ========================================================================= #
30
+ # === initialize
31
+ # ========================================================================= #
32
+ def initialize(
33
+ i = nil,
34
+ run_already = true
35
+ )
36
+ reset
37
+ set_commandline_arguments(i)
38
+ run if run_already
39
+ end
40
+
41
+ # ========================================================================= #
42
+ # === reset (reset tag)
43
+ # ========================================================================= #
44
+ def reset
45
+ super()
46
+ # ======================================================================= #
47
+ # === :dataset
48
+ # ======================================================================= #
49
+ @internal_hash[:dataset] = YAML.load_file(USE_THIS_FILE)
50
+ set_be_quiet # Or set_be_verbose
51
+ end
52
+
53
+ # ========================================================================= #
54
+ # === run (run tag)
55
+ # ========================================================================= #
56
+ def run
57
+ _ = commandline_arguments?
58
+ sequence1 = _[0]
59
+ sequence2 = _[1]
60
+ do_work_through_these_two_sequences(sequence1, sequence2)
61
+ end
62
+
63
+ # ========================================================================= #
64
+ # === do_work_through_these_two_sequences
65
+ # ========================================================================= #
66
+ def do_work_through_these_two_sequences(a, b)
67
+ dataset = @internal_hash[:dataset]
68
+ b_chars = b.chars
69
+ total_score = 0
70
+ gap_is_open = false
71
+ be_verbose = be_verbose?
72
+ a.chars.each_with_index {|char, index|
73
+ char1 = char
74
+ char2 = b_chars[index]
75
+ if char1 == '-' or char2 == '-'
76
+ if gap_is_open
77
+ total_score += (-2)
78
+ if be_verbose
79
+ erev 'Gap extension cost for the two elements '+char1+char2+
80
+ ' total score is now: '+tomato(total_score.to_s)+rev+')'
81
+ end
82
+ else
83
+ total_score += (-12)
84
+ if be_verbose
85
+ erev 'Gap open cost for the two elements '+char1+char2+
86
+ ' total score is now: '+tomato(total_score.to_s)+rev+')'
87
+ end
88
+ end
89
+ gap_is_open = true
90
+ else
91
+ gap_is_open = false # Always close it then.
92
+ value = dataset[char1 + char2]
93
+ total_score += value
94
+ if be_verbose
95
+ erev 'Normal BLOSUM50 cost for the two elements '+
96
+ char1+char2+' '+
97
+ tomato(
98
+ '(add '+value.to_s+
99
+ ' total score is now: '+total_score.to_s+')'
100
+ )+rev
101
+ end
102
+
103
+ end
104
+ }
105
+ erev 'The final score of these two sequences is '+royalblue(total_score)+rev+'.'
106
+ end
107
+
108
+ # ========================================================================= #
109
+ # === Bioroebe::CompareTheseTwoSequencesViaBlosum[]
110
+ # ========================================================================= #
111
+ def self.[](i = ARGV)
112
+ new(i)
113
+ end
114
+
115
+ end; end
116
+
117
+ if __FILE__ == $PROGRAM_NAME
118
+ Bioroebe::CompareTheseTwoSequencesViaBlosum.new(ARGV)
119
+ end # comparethesetwosequencesviablosum GSAQVKGHGKKVADALTNAVAHVDDMPNALSALSD----LHAHK GSGYLVGDSLTFVDLL--VAQHTADLLAANAALLDEFPQFKAHQ
@@ -28,7 +28,7 @@
28
28
  # require 'bioroebe/utility_scripts/compseq/compseq.rb'
29
29
  # Bioroebe::Compseq.new(ARGV)
30
30
  # =========================================================================== #
31
- require 'bioroebe/base/commandline_application/commandline_application.rb'
31
+ require 'bioroebe/requires/commandline_application.rb'
32
32
 
33
33
  module Bioroebe
34
34
 
@@ -105,9 +105,9 @@ class Compseq < ::Bioroebe::CommandlineApplication # === Bioroebe::Compseq
105
105
  super()
106
106
  infer_the_namespace
107
107
  # ======================================================================= #
108
- # === @identifier
108
+ # === @internal_hash[:identifier]
109
109
  # ======================================================================= #
110
- @identifier = nil
110
+ @internal_hash[:identifier] = nil
111
111
  # ======================================================================= #
112
112
  # === @hash
113
113
  # ======================================================================= #
@@ -124,7 +124,7 @@ class Compseq < ::Bioroebe::CommandlineApplication # === Bioroebe::Compseq
124
124
  def set_word_size(
125
125
  i = DEFAULT_WORD_SIZE
126
126
  )
127
- @word_size = i
127
+ @internal_hash[:word_size] = i
128
128
  end
129
129
 
130
130
  # ========================================================================= #
@@ -140,8 +140,8 @@ class Compseq < ::Bioroebe::CommandlineApplication # === Bioroebe::Compseq
140
140
  # === Handle empty input given next
141
141
  # ======================================================================= #
142
142
  if i.empty?
143
- opnn; erev 'Please provide an input, either an existing file, or the'
144
- opnn; erev 'raw FASTA sequence embedded in "" quotes, for instance.'
143
+ opnerev 'Please provide an input, either an existing file, or the'
144
+ opnerev 'raw FASTA sequence embedded in "" quotes, for instance.'
145
145
  end
146
146
  # ======================================================================= #
147
147
  # === Handle > FASTA identifier next
@@ -171,14 +171,16 @@ class Compseq < ::Bioroebe::CommandlineApplication # === Bioroebe::Compseq
171
171
  # ========================================================================= #
172
172
  def set_identifier(i)
173
173
  i =~ />gi\|\d+\|ref\|(NM.+)\|/ # http://rubular.com/r/dbx08WzdAZ
174
- @identifier = $1.to_s.dup
174
+ @internal_hash[:identifier] = $1.to_s.dup
175
175
  end
176
176
 
177
177
  # ========================================================================= #
178
178
  # === identifier?
179
+ #
180
+ # This method must guarantee to return a String.
179
181
  # ========================================================================= #
180
182
  def identifier?
181
- @identifier.to_s
183
+ @internal_hash[:identifier].to_s
182
184
  end
183
185
 
184
186
  # ========================================================================= #
@@ -379,7 +381,7 @@ class Compseq < ::Bioroebe::CommandlineApplication # === Bioroebe::Compseq
379
381
  # === word_size?
380
382
  # ========================================================================= #
381
383
  def word_size?
382
- @word_size
384
+ @internal_hash[:word_size]
383
385
  end
384
386
 
385
387
  # ========================================================================= #
@@ -9,15 +9,20 @@
9
9
  # You have to input several sequences to this class - at the least
10
10
  # two.
11
11
  # =========================================================================== #
12
- # require 'bioroebe/utility_scripts/consensus_sequence.rb'
12
+ # require 'bioroebe/utility_scripts/consensus_sequence/consensus_sequence.rb'
13
13
  # Bioroebe::ConsensusSequence.new(ARGV)
14
14
  # =========================================================================== #
15
- require 'bioroebe/base/commandline_application/commandline_application.rb'
15
+ require 'bioroebe/requires/commandline_application.rb'
16
16
 
17
17
  module Bioroebe
18
18
 
19
19
  class ConsensusSequence < ::Bioroebe::CommandlineApplication # === Bioroebe::ConsensusSequence
20
20
 
21
+ # ========================================================================= #
22
+ # === A_T_or_C
23
+ # ========================================================================= #
24
+ A_T_or_C = %w( A T C )
25
+
21
26
  # ========================================================================= #
22
27
  # === initialize
23
28
  # ========================================================================= #
@@ -164,12 +169,13 @@ class ConsensusSequence < ::Bioroebe::CommandlineApplication # === Bioroebe::Con
164
169
  %w( A T ).sample
165
170
  end
166
171
 
167
-
168
172
  # ========================================================================= #
169
173
  # === return_A_or_T_or_C
174
+ #
175
+ # This method will randomly pick either A, T or C.
170
176
  # ========================================================================= #
171
177
  def return_A_or_T_or_C
172
- %w( A T C ).sample
178
+ A_T_or_C.sample
173
179
  end
174
180
 
175
181
  # ========================================================================= #
@@ -198,6 +204,9 @@ class ConsensusSequence < ::Bioroebe::CommandlineApplication # === Bioroebe::Con
198
204
  be_verbose = be_verbose?
199
205
  )
200
206
  case be_verbose
207
+ # ======================================================================= #
208
+ # === :be_verbose
209
+ # ======================================================================= #
201
210
  when :be_verbose
202
211
  be_verbose = true
203
212
  end
@@ -14,12 +14,12 @@
14
14
  #
15
15
  # Usage example:
16
16
  #
17
- # Bioroebe::CreateBatchEntrezFile.new
17
+ # Bioroebe::CreateBatchEntrezFile.new(ARGV)
18
18
  #
19
19
  # =========================================================================== #
20
- # require 'bioroebe/utility_scripts/create_batch_entrez_file.rb'
20
+ # require 'bioroebe/utility_scripts/create_batch_entrez_file/create_batch_entrez_file.rb'
21
21
  # =========================================================================== #
22
- require 'bioroebe/base/commandline_application/commandline_application.rb'
22
+ require 'bioroebe/requires/commandline_application.rb'
23
23
 
24
24
  module Bioroebe
25
25
 
@@ -95,7 +95,7 @@ https://www.ncbi.nlm.nih.gov/nuccore/NC_003197.2
95
95
  # ========================================================================= #
96
96
  def store_input_into_a_file
97
97
  this_file = 'input_files.fasta'
98
- opnn; e "Now storing into `#{sfile(this_file)}`."
98
+ opnerev "Now storing into `#{sfile(this_file)}`."
99
99
  what = @input.join(N)
100
100
  into = this_file
101
101
  write_what_into(what, into)
@@ -111,7 +111,7 @@ https://www.ncbi.nlm.nih.gov/nuccore/NC_003197.2
111
111
  # ========================================================================= #
112
112
  # === Bioroebe::CreateBatchEntrezFile[]
113
113
  # ========================================================================= #
114
- def self.[](i = '')
114
+ def self.[](i = ARGV)
115
115
  new(i)
116
116
  end
117
117
 
@@ -23,16 +23,16 @@
23
23
  #
24
24
  # Usage example:
25
25
  #
26
- # Bioroebe::DetermineAntigenicAreas.new
26
+ # Bioroebe::DetermineAntigenicAreas.new(ARGV)
27
27
  #
28
28
  # =========================================================================== #
29
- # require 'bioroebe/utility_scripts/determine_antigenic_areas.rb'
29
+ # require 'bioroebe/utility_scripts/determine_antigenic_areas/determine_antigenic_areas.rb'
30
30
  # =========================================================================== #
31
- require 'bioroebe/base/base.rb'
31
+ require 'bioroebe/requires/commandline_application.rb'
32
32
 
33
33
  module Bioroebe
34
34
 
35
- class DetermineAntigenicAreas < Base # === Bioroebe::DetermineAntigenicAreas.new
35
+ class DetermineAntigenicAreas < ::Bioroebe::CommandlineApplication # === Bioroebe::DetermineAntigenicAreas
36
36
 
37
37
  # ========================================================================= #
38
38
  # === ARRAY_IMPORTANT_HYDROPHOBIC_RESIDUES
@@ -104,7 +104,7 @@ class DetermineAntigenicAreas < Base # === Bioroebe::DetermineAntigenicAreas.new
104
104
  # ========================================================================= #
105
105
  # === Bioroebe::DetermineAntigenicAreas[]
106
106
  # ========================================================================= #
107
- def self.[](i = '')
107
+ def self.[](i = ARGV)
108
108
  new(i)
109
109
  end
110
110
 
@@ -17,7 +17,7 @@
17
17
  # =========================================================================== #
18
18
  # require 'bioroebe/utility_scripts/determine_missing_nucleotides_percentage.rb'
19
19
  # =========================================================================== #
20
- require 'bioroebe/base/commandline_application/commandline_application.rb'
20
+ require 'bioroebe/requires/commandline_application.rb'
21
21
 
22
22
  module Bioroebe
23
23
 
@@ -67,18 +67,10 @@ class DetermineMissingNucleotidesPercentage < ::Bioroebe::CommandlineApplication
67
67
  # === sanitize_input
68
68
  # ========================================================================= #
69
69
  def sanitize_input
70
- if input?.include? ' + '
71
- set_input(input?.gsub(/ \+/,''))
72
- end
73
- if input?.include? 'content'
74
- set_input(input?.gsub(/content/,''))
75
- end
76
- if input?.include? 'is'
77
- set_input(input?.gsub(/is/,''))
78
- end
79
- if input?.include? 'percent'
80
- set_input(input?.gsub(/percent/,'%'))
81
- end
70
+ set_input(input?.gsub(/ \+/,'')) if input?.include? ' + '
71
+ set_input(input?.gsub(/content/,'')) if input?.include? 'content'
72
+ set_input(input?.gsub(/is/,'')) if input?.include? 'is'
73
+ set_input(input?.gsub(/percent/,'%')) if input?.include? 'percent'
82
74
  @input.delete!('.')
83
75
  @input.strip!
84
76
  end
@@ -109,11 +101,20 @@ class DetermineMissingNucleotidesPercentage < ::Bioroebe::CommandlineApplication
109
101
  @hash[:c] = @percentage / 2
110
102
  end; alias determine_atcg_content determine_a_t_c_g_content # === determine_atcg_content
111
103
 
104
+ # ========================================================================= #
105
+ # === hash?
106
+ # ========================================================================= #
107
+ def hash?
108
+ @hash
109
+ end
110
+
112
111
  # ========================================================================= #
113
112
  # === report_atcg_content
114
113
  # ========================================================================= #
115
- def report_atcg_content
116
- @hash.each_pair {|key, value|
114
+ def report_atcg_content(
115
+ i = hash?
116
+ )
117
+ i.each_pair {|key, value|
117
118
  erev "#{key.to_s.upcase} has: "\
118
119
  "#{steelblue(value.to_s+'%')}#{rev}"
119
120
  }
@@ -10,19 +10,19 @@
10
10
  # require 'bioroebe/utility_scripts/display_open_reading_frames/display_open_reading_frames.rb'
11
11
  # Bioroebe::DisplayOpenReadingFrames.new(ARGV)
12
12
  # =========================================================================== #
13
- require 'bioroebe/base/commandline_application/commandline_application.rb'
14
- require 'bioroebe/utility_scripts/display_open_reading_frames/determine.rb'
15
- require 'bioroebe/utility_scripts/display_open_reading_frames/initialize.rb'
16
- require 'bioroebe/utility_scripts/display_open_reading_frames/menu.rb'
17
- require 'bioroebe/utility_scripts/display_open_reading_frames/misc.rb'
18
- require 'bioroebe/utility_scripts/display_open_reading_frames/report.rb'
19
- require 'bioroebe/utility_scripts/display_open_reading_frames/reset.rb'
13
+ require 'bioroebe/requires/commandline_application.rb'
20
14
 
21
15
  module Bioroebe
22
16
 
23
17
  class DisplayOpenReadingFrames < ::Bioroebe::CommandlineApplication # === Bioroebe::DisplayOpenReadingFrames
24
18
 
25
19
  require 'bioroebe/sequence/dna.rb'
20
+ require 'bioroebe/utility_scripts/display_open_reading_frames/determine.rb'
21
+ require 'bioroebe/utility_scripts/display_open_reading_frames/initialize.rb'
22
+ require 'bioroebe/utility_scripts/display_open_reading_frames/menu.rb'
23
+ require 'bioroebe/utility_scripts/display_open_reading_frames/misc.rb'
24
+ require 'bioroebe/utility_scripts/display_open_reading_frames/report.rb'
25
+ require 'bioroebe/utility_scripts/display_open_reading_frames/reset.rb'
26
26
 
27
27
  end; end
28
28
 
@@ -12,7 +12,7 @@ class DisplayOpenReadingFrames < ::Bioroebe::CommandlineApplication # === Bioroe
12
12
  # === set_dna_sequence
13
13
  # ========================================================================= #
14
14
  def set_dna_sequence(
15
- i = @commandline_arguments.first
15
+ i = commandline_arguments?.first
16
16
  )
17
17
  i = i.to_s.dup # We always want a free, unfrozen sequence here.
18
18
  # ======================================================================= #
@@ -8,6 +8,8 @@ module Bioroebe
8
8
 
9
9
  class DisplayOpenReadingFrames < ::Bioroebe::CommandlineApplication # === Bioroebe::DisplayOpenReadingFrames
10
10
 
11
+ require 'bioroebe/codons/start_codons.rb'
12
+
11
13
  # ========================================================================= #
12
14
  # === show_the_intro_for_this_class
13
15
  # ========================================================================= #
@@ -12,10 +12,10 @@
12
12
  # Bioroebe::DotAlignment.new(ARGV)
13
13
  #
14
14
  # =========================================================================== #
15
- # require 'bioroebe/utility_scripts/dot_alignment_frames.rb'
15
+ # require 'bioroebe/utility_scripts/dot_alignment_frames/dot_alignment_frames.rb'
16
16
  # Bioroebe::DotAlignment.new(ARGV)
17
17
  # =========================================================================== #
18
- require 'bioroebe/base/commandline_application/commandline_application.rb'
18
+ require 'bioroebe/requires/commandline_application.rb'
19
19
 
20
20
  module Bioroebe
21
21
 
@@ -156,7 +156,7 @@ class DotAlignment < ::Bioroebe::CommandlineApplication # === Bioroebe::DotAlign
156
156
  # ========================================================================= #
157
157
  # === Bioroebe::DotAlignment[]
158
158
  # ========================================================================= #
159
- def self.[](i = '')
159
+ def self.[](i = ARGV)
160
160
  new(i)
161
161
  end
162
162
 
@@ -13,7 +13,7 @@
13
13
  # require 'bioroebe/utility_scripts/download_files_from_rebase.rb'
14
14
  # Bioroebe::DownloadFilesFromRebase.new(ARGV)
15
15
  # =========================================================================== #
16
- require 'bioroebe/base/commandline_application/commandline_application.rb'
16
+ require 'bioroebe/requires/commandline_application.rb'
17
17
 
18
18
  module Bioroebe
19
19
 
@@ -42,16 +42,16 @@ class DownloadFilesFromRebase < ::Bioroebe::CommandlineApplication # === Bioroeb
42
42
  def reset
43
43
  super()
44
44
  # ======================================================================= #
45
- # === @array_download_these_remote_files
45
+ # === :array_download_these_remote_files
46
46
  # ======================================================================= #
47
- @array_download_these_remote_files = %w( emboss_e.txt )
47
+ @internal_hash[:array_download_these_remote_files] = %w( emboss_e.txt )
48
48
  end
49
49
 
50
50
  # ========================================================================= #
51
51
  # === run
52
52
  # ========================================================================= #
53
53
  def run
54
- @array_download_these_remote_files.each {|this_remote_file|
54
+ @internal_hash[:array_download_these_remote_files].each {|this_remote_file|
55
55
  _ = REMOTE_BASE_URL+this_remote_file
56
56
  erev "Now dowloading #{sfile(_)}#{rev}."
57
57
  esystem "wget #{_}"
@@ -61,7 +61,7 @@ class DownloadFilesFromRebase < ::Bioroebe::CommandlineApplication # === Bioroeb
61
61
  # ========================================================================= #
62
62
  # === Bioroebe::DownloadFilesFromRebase[]
63
63
  # ========================================================================= #
64
- def self.[](i)
64
+ def self.[](i = ARGV)
65
65
  new(i)
66
66
  end
67
67