bioroebe 0.12.24 → 0.13.31

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Files changed (503) hide show
  1. checksums.yaml +4 -4
  2. data/LICENSE.md +7 -8
  3. data/README.md +566 -354
  4. data/bin/all_positions_of_this_nucleotide +1 -1
  5. data/bin/aminoacid_frequencies +1 -1
  6. data/bin/automatically_rename_this_fasta_file +1 -1
  7. data/bin/base_composition +1 -1
  8. data/bin/batch_create_windows_executables +1 -1
  9. data/bin/bioroebe +12 -1
  10. data/bin/bioroebe_cat +7 -0
  11. data/bin/calculate_exponential_growth +7 -0
  12. data/bin/calculate_n50_value +1 -1
  13. data/bin/calculate_the_frequencies_of_this_species +7 -0
  14. data/bin/chunked_display +1 -1
  15. data/bin/codon_frequency +1 -1
  16. data/bin/codon_to_aminoacid +1 -1
  17. data/bin/colourize_this_fasta_sequence +1 -1
  18. data/bin/complementary_dna_strand +1 -1
  19. data/bin/complementary_rna_strand +1 -1
  20. data/bin/consensus_sequence +1 -1
  21. data/bin/dna_to_rna +1 -1
  22. data/bin/downcase_chunked_display +1 -1
  23. data/bin/download_this_pdb +1 -1
  24. data/bin/fasta_index +1 -1
  25. data/bin/fetch_data_from_uniprot +1 -1
  26. data/bin/filter_away_invalid_nucleotides +1 -1
  27. data/bin/find_substring +1 -1
  28. data/bin/input_as_dna +1 -1
  29. data/bin/is_palindrome +1 -1
  30. data/bin/leading_five_prime +1 -1
  31. data/bin/longest_ORF +1 -1
  32. data/bin/longest_substring +1 -1
  33. data/bin/open_reading_frames +1 -1
  34. data/bin/partner_nucleotide +1 -1
  35. data/bin/plain_palindrome +1 -1
  36. data/bin/random_dna_sequence +1 -1
  37. data/bin/random_sequence +1 -1
  38. data/bin/raw_hamming_distance +1 -1
  39. data/bin/return_longest_substring_via_LCS_algorithm +1 -1
  40. data/bin/reverse_sequence +1 -1
  41. data/bin/short_aminoacid_letter_from_long_aminoacid_name +1 -1
  42. data/bin/show_atomic_composition +1 -1
  43. data/bin/show_fasta_header +1 -1
  44. data/bin/show_nucleotide_sequence +1 -1
  45. data/bin/show_this_dna_sequence +1 -1
  46. data/bin/show_time_now +7 -0
  47. data/bin/sort_aminoacid_based_on_its_hydrophobicity +1 -1
  48. data/bin/strict_filter_away_invalid_aminoacids +1 -1
  49. data/{lib/bioroebe/base/reset.rb → bin/three_delimiter} +9 -6
  50. data/bin/three_to_one +1 -1
  51. data/bin/to_rna +1 -1
  52. data/bin/trailing_three_prime +1 -1
  53. data/bin/upcase_this_aminoacid_sequence_and_remove_numbers +1 -1
  54. data/bioroebe.gemspec +6 -7
  55. data/doc/README.gen +534 -322
  56. data/doc/blosum/blosum.md +4 -0
  57. data/doc/compatibility/BIO_PHP.md +20 -18
  58. data/doc/compatibility/README.md +2 -3
  59. data/doc/compatibility/emboss.md +5 -3
  60. data/doc/{extensive_usage_example.md → extensive_usage_example/extensive_usage_example.md} +4 -2
  61. data/doc/{instructions_for_the_taxonomy_subproject.md → instructions_for_the_taxonomy_subproject/instructions_for_the_taxonomy_subproject.md} +36 -33
  62. data/doc/{legacy_paths.md → legacy_paths/legacy_paths.md} +3 -3
  63. data/doc/statistics/statistics.md +12 -10
  64. data/doc/todo/bioroebe_GUI_todo.md +6 -1
  65. data/doc/todo/bioroebe_java_todo.md +3 -2
  66. data/doc/todo/bioroebe_todo.md +328 -310
  67. data/doc/{using_biomart.md → using_biomart/using_biomart.md} +7 -3
  68. data/lib/bioroebe/abstract/features.rb +0 -0
  69. data/lib/bioroebe/aminoacids/aminoacid_substitution.rb +1 -1
  70. data/lib/bioroebe/aminoacids/aminoacids_mass_table.rb +3 -1
  71. data/lib/bioroebe/aminoacids/codon_percentage.rb +18 -10
  72. data/lib/bioroebe/aminoacids/create_random_aminoacids.rb +5 -2
  73. data/lib/bioroebe/aminoacids/deduce_aminoacid_sequence.rb +90 -64
  74. data/lib/bioroebe/aminoacids/display_aminoacid_table.rb +1 -3
  75. data/lib/bioroebe/aminoacids/show_hydrophobicity.rb +2 -2
  76. data/lib/bioroebe/annotations/create_annotation_format.rb +2 -2
  77. data/lib/bioroebe/base/base.rb +101 -6
  78. data/lib/bioroebe/base/base_module/base_module.rb +9 -1
  79. data/lib/bioroebe/base/colours.rb +3 -0
  80. data/lib/bioroebe/base/colours_for_base/colours_for_base.rb +80 -44
  81. data/lib/bioroebe/base/commandline_application/README.md +1 -1
  82. data/lib/bioroebe/base/commandline_application/commandline_application.rb +661 -22
  83. data/lib/bioroebe/base/commandline_application/commandline_arguments.rb +2 -1
  84. data/lib/bioroebe/base/infer_the_namespace_module/infer_the_namespace_module.rb +37 -0
  85. data/lib/bioroebe/base/internal_hash_module/internal_hash_module.rb +1 -6
  86. data/lib/bioroebe/base/prototype/prototype.rb +155 -14
  87. data/lib/bioroebe/biomart/attribute.rb +1 -1
  88. data/lib/bioroebe/biomart/biomart.rb +8 -9
  89. data/lib/bioroebe/biomart/server.rb +1 -1
  90. data/lib/bioroebe/blosum/blosum.rb +2 -2
  91. data/lib/bioroebe/calculate/calculate_blosum_score.rb +5 -3
  92. data/lib/bioroebe/calculate/calculate_gc_content.rb +1 -1
  93. data/lib/bioroebe/calculate/calculate_levensthein_distance.rb +5 -3
  94. data/lib/bioroebe/calculate/calculate_melting_temperature.rb +2 -10
  95. data/lib/bioroebe/calculate/calculate_melting_temperature_for_more_than_thirteen_nucleotides.rb +6 -15
  96. data/lib/bioroebe/calculate/calculate_the_position_specific_scoring_matrix.rb +4 -2
  97. data/lib/bioroebe/cell/cell.rb +3 -2
  98. data/lib/bioroebe/cell/specialized_cells/B_cell.rb +60 -0
  99. data/lib/bioroebe/cell/specialized_cells/Macrophage.rb +60 -0
  100. data/lib/bioroebe/cell/specialized_cells/README.md +5 -0
  101. data/lib/bioroebe/cell/specialized_cells/T_cell.rb +60 -0
  102. data/lib/bioroebe/cleave_and_digest/cleave.rb +3 -1
  103. data/lib/bioroebe/cleave_and_digest/digestion.rb +1 -1
  104. data/lib/bioroebe/codon_tables/frequencies/10090_Mus_musculus.yml +93 -0
  105. data/lib/bioroebe/codon_tables/frequencies/107243_Thlaspi_caerulescens.yml +72 -0
  106. data/lib/bioroebe/codon_tables/frequencies/parse_frequency_table.rb +2 -2
  107. data/lib/bioroebe/codons/codon_table.rb +10 -2
  108. data/lib/bioroebe/codons/codons.rb +3 -3
  109. data/lib/bioroebe/codons/convert_this_codon_to_that_aminoacid.rb +18 -15
  110. data/lib/bioroebe/codons/determine_optimal_codons.rb +1 -1
  111. data/lib/bioroebe/codons/possible_codons_for_this_aminoacid.rb +4 -2
  112. data/lib/bioroebe/codons/show_codon_tables.rb +1 -1
  113. data/lib/bioroebe/codons/show_codon_usage.rb +1 -2
  114. data/lib/bioroebe/codons/show_this_codon_table.rb +2 -2
  115. data/lib/bioroebe/codons/start_codons.rb +7 -3
  116. data/lib/bioroebe/colours/colour_schemes/README.md +1 -1
  117. data/lib/bioroebe/colours/colour_schemes/array_available_colour_schemes.rb +3 -3
  118. data/lib/bioroebe/colours/colour_schemes/colour_scheme.rb +3 -3
  119. data/lib/bioroebe/colours/colour_schemes/colour_scheme_demo.rb +4 -3
  120. data/lib/bioroebe/colours/colour_schemes/helix.rb +3 -1
  121. data/lib/bioroebe/colours/colour_schemes/hydropathy.rb +3 -1
  122. data/lib/bioroebe/colours/colour_schemes/score.rb +13 -2
  123. data/lib/bioroebe/colours/colour_schemes/strand.rb +3 -1
  124. data/lib/bioroebe/colours/colour_schemes/turn.rb +3 -1
  125. data/lib/bioroebe/colours/colour_schemes/zappo.rb +1 -1
  126. data/lib/bioroebe/{toplevel_methods/colourize_related_methods.rb → colours/colourize_related_code.rb} +1 -3
  127. data/lib/bioroebe/colours/colourize_sequence.rb +3 -1
  128. data/lib/bioroebe/colours/colours.rb +172 -15
  129. data/lib/bioroebe/configuration/configuration.rb +1 -1
  130. data/lib/bioroebe/constants/GUIs.rb +2 -2
  131. data/lib/bioroebe/constants/constants.rb +1349 -0
  132. data/lib/bioroebe/conversions/convert_aminoacid_to_dna.rb +8 -13
  133. data/lib/bioroebe/conversions/dna_to_aminoacid_sequence.rb +9 -3
  134. data/lib/bioroebe/count/count_amount_of_aminoacids.rb +11 -10
  135. data/lib/bioroebe/count/count_amount_of_nucleotides.rb +1 -1
  136. data/lib/bioroebe/count/count_at.rb +2 -1
  137. data/lib/bioroebe/databases/download_taxonomy_database.rb +1 -1
  138. data/lib/bioroebe/dotplots/advanced_dotplot.rb +2 -2
  139. data/lib/bioroebe/electron_microscopy/coordinate_analyzer.rb +2 -2
  140. data/lib/bioroebe/electron_microscopy/fix_pos_file.rb +2 -2
  141. data/lib/bioroebe/electron_microscopy/flipy.rb +2 -2
  142. data/lib/bioroebe/electron_microscopy/generate_em2em_file.rb +3 -11
  143. data/lib/bioroebe/electron_microscopy/parse_coordinates.rb +6 -6
  144. data/lib/bioroebe/electron_microscopy/read_file_xmd.rb +6 -6
  145. data/lib/bioroebe/electron_microscopy/simple_star_file_generator.rb +2 -2
  146. data/lib/bioroebe/enzymes/has_this_restriction_enzyme.rb +1 -1
  147. data/lib/bioroebe/enzymes/restriction_enzyme.rb +1 -1
  148. data/lib/bioroebe/enzymes/restriction_enzymes/statistics.rb +4 -3
  149. data/lib/bioroebe/enzymes/restriction_enzymes_file.rb +1 -1
  150. data/lib/bioroebe/enzymes/return_sequence_that_is_cut_via_restriction_enzyme.rb +4 -3
  151. data/lib/bioroebe/enzymes/show_restriction_enzymes.rb +3 -3
  152. data/lib/bioroebe/ext/main.cpp +0 -1
  153. data/lib/bioroebe/fasta_and_fastq/autocorrect_the_name_of_this_fasta_file.rb +3 -3
  154. data/lib/bioroebe/fasta_and_fastq/compact_fasta_file/compact_fasta_file.rb +1 -1
  155. data/lib/bioroebe/fasta_and_fastq/display_how_many_fasta_entries_are_in_this_directory.rb +1 -1
  156. data/lib/bioroebe/fasta_and_fastq/download_fasta.rb +8 -14
  157. data/lib/bioroebe/fasta_and_fastq/fasta_defline/fasta_defline.rb +1 -1
  158. data/lib/bioroebe/fasta_and_fastq/fasta_to_yaml/fasta_to_yaml.rb +1 -1
  159. data/lib/bioroebe/fasta_and_fastq/fastq_format_explainer.rb +1 -1
  160. data/lib/bioroebe/fasta_and_fastq/length_modifier/length_modifier.rb +1 -1
  161. data/lib/bioroebe/fasta_and_fastq/parse_fasta/parse_fasta.rb +37 -11
  162. data/lib/bioroebe/fasta_and_fastq/parse_fastq/parse_fastq.rb +2 -2
  163. data/lib/bioroebe/fasta_and_fastq/return_fasta_subsection_of_this_file.rb +1 -1
  164. data/lib/bioroebe/fasta_and_fastq/show_fasta_headers.rb +5 -13
  165. data/lib/bioroebe/fasta_and_fastq/show_fasta_statistics.rb +1 -1
  166. data/lib/bioroebe/fasta_and_fastq/simplify_fasta_header/simplify_fasta_header.rb +1 -1
  167. data/lib/bioroebe/fasta_and_fastq/split_this_fasta_file_into_chromosomes/reset.rb +3 -6
  168. data/lib/bioroebe/fasta_and_fastq/split_this_fasta_file_into_chromosomes/split_this_fasta_file_into_chromosomes.rb +3 -3
  169. data/lib/bioroebe/genbank/genbank_flat_file_format_generator.rb +20 -11
  170. data/lib/bioroebe/genome/genome.rb +1 -1
  171. data/lib/bioroebe/genomes/genome_pattern.rb +17 -16
  172. data/lib/bioroebe/genomes/genome_retriever.rb +4 -2
  173. data/lib/bioroebe/gui/experimental/snapgene/snapgene.rb +10 -13
  174. data/lib/bioroebe/gui/universal_widgets/alignment/alignment.rb +557 -0
  175. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/aminoacid_composition/aminoacid_composition.rb +498 -198
  176. data/lib/bioroebe/gui/universal_widgets/anti_sense_strand/anti_sense_strand.rb +665 -0
  177. data/lib/bioroebe/gui/universal_widgets/blosum_matrix_viewer/blosum_matrix_viewer.rb +329 -0
  178. data/lib/bioroebe/gui/universal_widgets/calculate_cell_numbers_of_bacteria/calculate_cell_numbers_of_bacteria.rb +423 -0
  179. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/controller/controller.rb +170 -118
  180. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/dna_to_aminoacid_widget/dna_to_aminoacid_widget.rb +277 -215
  181. data/lib/bioroebe/gui/{shared_code/dna_to_reverse_complement_widget/dna_to_reverse_complement_widget_module.rb → universal_widgets/dna_to_reverse_complement_widget/dna_to_reverse_complement_widget.rb} +297 -107
  182. data/lib/bioroebe/gui/universal_widgets/fasta_table_widget/fasta_table_widget.rb +643 -0
  183. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/format_converter/format_converter.rb +236 -164
  184. data/lib/bioroebe/gui/universal_widgets/gene/gene.rb +278 -0
  185. data/lib/bioroebe/gui/universal_widgets/hamming_distance/hamming_distance.rb +646 -0
  186. data/lib/bioroebe/gui/{shared_code/levensthein_distance/levensthein_distance_module.rb → universal_widgets/levensthein_distance/levensthein_distance.rb} +313 -88
  187. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/nucleotide_analyser/nucleotide_analyser.rb +281 -189
  188. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/parse_pdb_file/parse_pdb_file.rb +265 -149
  189. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/primer_design_widget/primer_design_widget.rb +337 -263
  190. data/lib/bioroebe/gui/universal_widgets/protein_to_DNA/protein_to_DNA.rb +408 -0
  191. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/random_sequence/random_sequence.rb +245 -187
  192. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/restriction_enzymes/restriction_enzymes.rb +207 -137
  193. data/lib/bioroebe/gui/universal_widgets/shell/shell.rb +288 -0
  194. data/lib/bioroebe/gui/{gtk3/show_codon_table/misc.rb → universal_widgets/show_codon_table/show_codon_table.rb} +290 -110
  195. data/lib/bioroebe/gui/{shared_code/show_codon_usage/show_codon_usage_module.rb → universal_widgets/show_codon_usage/show_codon_usage.rb} +228 -47
  196. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/sizeseq/sizeseq.rb +151 -69
  197. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/three_to_one/three_to_one.rb +190 -127
  198. data/lib/bioroebe/gui/{gtk3 → universal_widgets}/www_finder/www_finder.rb +211 -152
  199. data/lib/bioroebe/images/images.html +953 -1170
  200. data/lib/bioroebe/images/misc/README.md +6 -0
  201. data/lib/bioroebe/images/misc/activation.avif +0 -0
  202. data/lib/bioroebe/images/misc/inhibition.avif +0 -0
  203. data/lib/bioroebe/images/misc/small_virus_logo.avif +0 -0
  204. data/lib/bioroebe/{constants/base_directory.rb → log_directory/log_directory.rb} +79 -59
  205. data/lib/bioroebe/matplotlib/matplotlib_generator.rb +1 -1
  206. data/lib/bioroebe/misc/quiz/three_letter_to_aminoacid.rb +1 -1
  207. data/lib/bioroebe/misc/ruler.rb +5 -5
  208. data/lib/bioroebe/misc/useful_formulas.rb +3 -3
  209. data/lib/bioroebe/ncbi/efetch.rb +1 -2
  210. data/lib/bioroebe/ngs/phred_quality_score_table.rb +3 -3
  211. data/lib/bioroebe/nucleotides/complementary_dna_strand.rb +3 -6
  212. data/lib/bioroebe/nucleotides/molecular_weight_of_nucleotides.rb +3 -3
  213. data/lib/bioroebe/nucleotides/most_likely_nucleotide_sequence_for_this_aminoacid_sequence.rb +6 -10
  214. data/lib/bioroebe/nucleotides/{show_nucleotide_sequence.rb → show_nucleotide_sequence/show_nucleotide_sequence.rb} +377 -255
  215. data/lib/bioroebe/palindromes/palindrome_2D_structure.rb +1 -1
  216. data/lib/bioroebe/palindromes/palindrome_finder.rb +1 -1
  217. data/lib/bioroebe/palindromes/palindrome_generator.rb +2 -10
  218. data/lib/bioroebe/parsers/biolang_parser.rb +1 -1
  219. data/lib/bioroebe/parsers/blosum_parser.rb +14 -19
  220. data/lib/bioroebe/parsers/genbank_parser.rb +2 -6
  221. data/lib/bioroebe/parsers/gff.rb +9 -9
  222. data/lib/bioroebe/parsers/parse_embl.rb +2 -6
  223. data/lib/bioroebe/parsers/stride_parser.rb +4 -12
  224. data/lib/bioroebe/patterns/analyse_glycosylation_pattern.rb +2 -2
  225. data/lib/bioroebe/patterns/is_this_sequence_a_EGF2_pattern.rb +6 -3
  226. data/lib/bioroebe/patterns/profile_pattern.rb +2 -2
  227. data/lib/bioroebe/patterns/rgg_scanner.rb +4 -2
  228. data/lib/bioroebe/{protein_structure → pdb_and_protein_structure}/alpha_helix.rb +2 -2
  229. data/lib/bioroebe/{pdb → pdb_and_protein_structure}/download_this_pdb.rb +2 -3
  230. data/lib/bioroebe/{pdb → pdb_and_protein_structure}/fetch_fasta_sequence_from_pdb.rb +4 -4
  231. data/lib/bioroebe/{protein_structure → pdb_and_protein_structure}/helical_wheel.rb +2 -2
  232. data/lib/bioroebe/{pdb → pdb_and_protein_structure}/parse_mmCIF_file.rb +1 -1
  233. data/lib/bioroebe/{pdb → pdb_and_protein_structure}/parse_pdb_file.rb +3 -3
  234. data/lib/bioroebe/{pdb → pdb_and_protein_structure}/report_secondary_structures_from_this_pdb_file.rb +3 -3
  235. data/lib/bioroebe/project/project.rb +3 -1
  236. data/lib/bioroebe/raw_sequence/README.md +8 -8
  237. data/lib/bioroebe/raw_sequence/raw_sequence.rb +11 -2
  238. data/lib/bioroebe/regexes/regexes.rb +1 -2
  239. data/lib/bioroebe/requires/commandline_application.rb +3 -1
  240. data/lib/bioroebe/requires/require_all_pdb_files.rb +1 -1
  241. data/lib/bioroebe/requires/require_all_taxonomy_files.rb +1 -1
  242. data/lib/bioroebe/requires/require_all_utility_scripts_files.rb +10 -0
  243. data/lib/bioroebe/requires/require_colours.rb +1 -1
  244. data/lib/bioroebe/requires/require_the_bioroebe_project.rb +5 -7
  245. data/lib/bioroebe/requires/require_the_bioroebe_sinatra_components.rb +1 -1
  246. data/lib/bioroebe/requires/require_the_constants.rb +2 -14
  247. data/lib/bioroebe/requires/require_yaml.rb +7 -5
  248. data/lib/bioroebe/sequence/alignment.rb +1 -1
  249. data/lib/bioroebe/sequence/dna.rb +4 -2
  250. data/lib/bioroebe/sequence/nucleotide_module/nucleotide_module.rb +22 -8
  251. data/lib/bioroebe/sequence/protein.rb +2 -2
  252. data/lib/bioroebe/sequence/reverse_complement.rb +3 -3
  253. data/lib/bioroebe/sequence/rna.rb +9 -8
  254. data/lib/bioroebe/sequence/sequence.rb +3 -3
  255. data/lib/bioroebe/shell/configuration/additionally_set_xorg_buffer.yml +0 -0
  256. data/lib/bioroebe/shell/configuration/may_we_show_the_startup_information.yml +0 -0
  257. data/lib/bioroebe/shell/configuration/upcase_nucleotides.yml +0 -0
  258. data/lib/bioroebe/shell/configuration/use_silent_startup.yml +1 -1
  259. data/lib/bioroebe/shell/help/class.rb +68 -19
  260. data/lib/bioroebe/shell/menu.rb +5244 -5322
  261. data/lib/bioroebe/shell/{readline/readline.rb → readline.rb} +1 -3
  262. data/lib/bioroebe/shell/shell.rb +11240 -453
  263. data/lib/bioroebe/siRNA/siRNA.rb +3 -3
  264. data/lib/bioroebe/{gui/shared_code/blosum_matrix_viewer/blosum_matrix_viewer_module.rb → sinatra/sinatra_interface.rb} +28 -19
  265. data/lib/bioroebe/{www/sinatra/sinatra.rb → sinatra/sinatra_wrapper.rb} +731 -754
  266. data/lib/bioroebe/string_matching/find_longest_substring.rb +2 -10
  267. data/lib/bioroebe/string_matching/find_longest_substring_via_LCS_algorithm.rb +4 -14
  268. data/lib/bioroebe/string_matching/hamming_distance.rb +11 -10
  269. data/lib/bioroebe/string_matching/levensthein.rb +5 -17
  270. data/lib/bioroebe/string_matching/simple_string_comparer.rb +48 -4
  271. data/lib/bioroebe/string_matching/smith_waterman.rb +11 -6
  272. data/lib/bioroebe/svg/glyph.rb +4 -1
  273. data/lib/bioroebe/svg/mini_feature.rb +1 -1
  274. data/lib/bioroebe/svg/page.rb +18 -7
  275. data/lib/bioroebe/svg/svgee.rb +22 -13
  276. data/lib/bioroebe/svg/track.rb +20 -4
  277. data/lib/bioroebe/taxonomy/chart.rb +2 -2
  278. data/lib/bioroebe/taxonomy/class_methods.rb +5 -6
  279. data/lib/bioroebe/taxonomy/constants.rb +1 -1
  280. data/lib/bioroebe/taxonomy/info/info.rb +1 -1
  281. data/lib/bioroebe/taxonomy/info/is_dna.rb +1 -1
  282. data/lib/bioroebe/taxonomy/interactive.rb +1 -2
  283. data/lib/bioroebe/taxonomy/menu.rb +1 -1
  284. data/lib/bioroebe/taxonomy/node.rb +1 -1
  285. data/lib/bioroebe/taxonomy/parse_fasta.rb +4 -2
  286. data/lib/bioroebe/taxonomy/shared.rb +5 -4
  287. data/lib/bioroebe/taxonomy/taxonomy.rb +2 -4
  288. data/lib/bioroebe/toplevel_methods/fasta_and_fastq.rb +3 -45
  289. data/lib/bioroebe/toplevel_methods/{is_on_roebe.rb → roebe.rb} +1 -11
  290. data/lib/bioroebe/toplevel_methods/taxonomy.rb +6 -12
  291. data/lib/bioroebe/toplevel_methods/toplevel_methods.rb +5568 -0
  292. data/lib/bioroebe/utility_scripts/align_open_reading_frames.rb +4 -3
  293. data/lib/bioroebe/utility_scripts/analyse_local_dataset.rb +2 -2
  294. data/lib/bioroebe/utility_scripts/check_for_mismatches/check_for_mismatches.rb +16 -9
  295. data/lib/bioroebe/utility_scripts/compacter/compacter.rb +4 -2
  296. data/lib/bioroebe/utility_scripts/compare_these_two_sequences_via_blosum.rb +119 -0
  297. data/lib/bioroebe/utility_scripts/compseq/compseq.rb +11 -9
  298. data/lib/bioroebe/utility_scripts/{consensus_sequence.rb → consensus_sequence/consensus_sequence.rb} +13 -4
  299. data/lib/bioroebe/utility_scripts/{create_batch_entrez_file.rb → create_batch_entrez_file/create_batch_entrez_file.rb} +5 -5
  300. data/lib/bioroebe/utility_scripts/{determine_antigenic_areas.rb → determine_antigenic_areas/determine_antigenic_areas.rb} +5 -5
  301. data/lib/bioroebe/utility_scripts/{determine_missing_nucleotides_percentage.rb → determine_missing_nucleotides_percentage/determine_missing_nucleotides_percentage.rb} +16 -15
  302. data/lib/bioroebe/utility_scripts/display_open_reading_frames/display_open_reading_frames.rb +7 -7
  303. data/lib/bioroebe/utility_scripts/display_open_reading_frames/misc.rb +1 -1
  304. data/lib/bioroebe/utility_scripts/display_open_reading_frames/report.rb +2 -0
  305. data/lib/bioroebe/utility_scripts/{dot_alignment.rb → dot_alignment/dot_alignment.rb} +3 -3
  306. data/lib/bioroebe/utility_scripts/{download_files_from_rebase.rb → download_files_from_rebase/download_files_from_rebase.rb} +5 -5
  307. data/lib/bioroebe/utility_scripts/fetch_data_from_uniprot/fetch_data_from_uniprot.rb +269 -0
  308. data/lib/bioroebe/utility_scripts/find_gene.rb +4 -2
  309. data/lib/bioroebe/utility_scripts/{mirror_repeat.rb → mirror_repeat/mirror_repeat.rb} +5 -5
  310. data/lib/bioroebe/utility_scripts/move_file_to_its_correct_location.rb +3 -3
  311. data/lib/bioroebe/utility_scripts/{parse_taxonomy.rb → parse_taxonomy/parse_taxonomy.rb} +15 -6
  312. data/lib/bioroebe/utility_scripts/{pathways.rb → pathways/pathways.rb} +4 -3
  313. data/lib/bioroebe/utility_scripts/{permutations.rb → permutations/permutations.rb} +3 -3
  314. data/lib/bioroebe/utility_scripts/punnet/punnet.rb +4 -2
  315. data/lib/bioroebe/utility_scripts/{show_this_dna_sequence.rb → show_this_dna_sequence/show_this_dna_sequence.rb} +1 -1
  316. data/lib/bioroebe/utility_scripts/showorf/showorf.rb +406 -10
  317. data/lib/bioroebe/version/version.rb +2 -2
  318. data/lib/bioroebe/viennarna/rnafold_wrapper.rb +5 -13
  319. data/lib/bioroebe/virus/individual_viruses/README.md +15 -0
  320. data/lib/bioroebe/virus/individual_viruses/tobacco_mosaic_virus.rb +40 -0
  321. data/lib/bioroebe/virus/virus.rb +76 -0
  322. data/lib/bioroebe/www/bioroebe.cgi +4 -3
  323. data/lib/bioroebe/www/embeddable_interface.rb +85 -49
  324. data/lib/bioroebe/yaml/agarose/agarose_concentrations.yml +6 -6
  325. data/lib/bioroebe/yaml/antisense/antisense.yml +2 -0
  326. data/lib/bioroebe/yaml/blosum/blosum50.yml +6 -0
  327. data/lib/bioroebe/yaml/blosum/blosum90.yml +2 -1
  328. data/lib/bioroebe/yaml/chromosomes/chromosome_numbers.yml +2 -2
  329. data/lib/bioroebe/yaml/configuration/temp_dir.yml +1 -1
  330. data/lib/bioroebe/yaml/consensus_sequences/consensus_sequences.yml +1 -0
  331. data/lib/bioroebe/yaml/enzymes/enzyme_classes.yml +7 -6
  332. data/lib/bioroebe/yaml/humans/human_chromosomes.yml +3 -3
  333. data/lib/bioroebe/yaml/mRNA/mRNA.yml +1 -5
  334. data/lib/bioroebe/yaml/nucleotides/abbreviations_for_nucleotides.yml +1 -0
  335. data/lib/bioroebe/yaml/nucleotides/nucleotide_density.yml +2 -1
  336. data/lib/bioroebe/yaml/promoters/35S.yml +3 -1
  337. data/lib/bioroebe/yaml/proteases/proteases.yml +3 -1
  338. data/lib/bioroebe/yaml/proteins/ubiquitin.yml +4 -1
  339. data/lib/bioroebe/yaml/restriction_enzymes/restriction_enzymes.yml +7 -7
  340. data/spec/testing_toplevel_method_editor.rb +1 -1
  341. data/spec/testing_toplevel_method_verbose.rb +1 -1
  342. data/test/testing_dna_to_rna_conversion.rb +1 -1
  343. metadata +127 -235
  344. data/doc/blosum.md +0 -5
  345. data/lib/bioroebe/base/commandline_application/aminoacids.rb +0 -33
  346. data/lib/bioroebe/base/commandline_application/directory.rb +0 -33
  347. data/lib/bioroebe/base/commandline_application/extract.rb +0 -22
  348. data/lib/bioroebe/base/commandline_application/misc.rb +0 -502
  349. data/lib/bioroebe/base/commandline_application/opn.rb +0 -47
  350. data/lib/bioroebe/base/commandline_application/reset.rb +0 -42
  351. data/lib/bioroebe/base/commandline_application/warnings.rb +0 -36
  352. data/lib/bioroebe/base/commandline_application/write_what_into.rb +0 -29
  353. data/lib/bioroebe/base/initialize.rb +0 -18
  354. data/lib/bioroebe/base/misc.rb +0 -129
  355. data/lib/bioroebe/base/namespace.rb +0 -16
  356. data/lib/bioroebe/base/prototype/e_and_ee.rb +0 -24
  357. data/lib/bioroebe/base/prototype/misc.rb +0 -114
  358. data/lib/bioroebe/base/prototype/mkdir.rb +0 -20
  359. data/lib/bioroebe/base/prototype/reset.rb +0 -36
  360. data/lib/bioroebe/colours/misc_colours.rb +0 -80
  361. data/lib/bioroebe/colours/rev.rb +0 -44
  362. data/lib/bioroebe/colours/sdir.rb +0 -21
  363. data/lib/bioroebe/colours/sfancy.rb +0 -21
  364. data/lib/bioroebe/colours/sfile.rb +0 -21
  365. data/lib/bioroebe/colours/simp.rb +0 -21
  366. data/lib/bioroebe/colours/swarn.rb +0 -29
  367. data/lib/bioroebe/constants/aminoacids_and_proteins.rb +0 -147
  368. data/lib/bioroebe/constants/carriage_return.rb +0 -14
  369. data/lib/bioroebe/constants/codon_tables.rb +0 -77
  370. data/lib/bioroebe/constants/database_constants.rb +0 -107
  371. data/lib/bioroebe/constants/files_and_directories.rb +0 -606
  372. data/lib/bioroebe/constants/misc.rb +0 -209
  373. data/lib/bioroebe/constants/newline.rb +0 -14
  374. data/lib/bioroebe/constants/nucleotides.rb +0 -121
  375. data/lib/bioroebe/constants/regex.rb +0 -28
  376. data/lib/bioroebe/constants/roebe.rb +0 -38
  377. data/lib/bioroebe/constants/row_terminator.rb +0 -16
  378. data/lib/bioroebe/constants/tabulator.rb +0 -14
  379. data/lib/bioroebe/constants/unicode.rb +0 -12
  380. data/lib/bioroebe/constants/urls.rb +0 -50
  381. data/lib/bioroebe/gui/gtk +0 -1
  382. data/lib/bioroebe/gui/gtk3/README.md +0 -2
  383. data/lib/bioroebe/gui/gtk3/alignment/alignment.rb +0 -306
  384. data/lib/bioroebe/gui/gtk3/anti_sense_strand/anti_sense_strand.rb +0 -29
  385. data/lib/bioroebe/gui/gtk3/blosum_matrix_viewer/blosum_matrix_viewer.rb +0 -195
  386. data/lib/bioroebe/gui/gtk3/calculate_cell_numbers_of_bacteria/calculate_cell_numbers_of_bacteria.rb +0 -105
  387. data/lib/bioroebe/gui/gtk3/dna_to_reverse_complement_widget/dna_to_reverse_complement_widget.rb +0 -188
  388. data/lib/bioroebe/gui/gtk3/fasta_table_widget/fasta_table_widget.rb +0 -322
  389. data/lib/bioroebe/gui/gtk3/gene/gene.rb +0 -181
  390. data/lib/bioroebe/gui/gtk3/hamming_distance/hamming_distance.rb +0 -383
  391. data/lib/bioroebe/gui/gtk3/levensthein_distance/levensthein_distance.rb +0 -174
  392. data/lib/bioroebe/gui/gtk3/protein_to_DNA/protein_to_DNA.rb +0 -181
  393. data/lib/bioroebe/gui/gtk3/show_codon_table/show_codon_table.rb +0 -101
  394. data/lib/bioroebe/gui/gtk3/show_codon_usage/show_codon_usage.rb +0 -145
  395. data/lib/bioroebe/gui/gtk3/three_to_one/title.rb +0 -23
  396. data/lib/bioroebe/gui/jruby/alignment/alignment.rb +0 -165
  397. data/lib/bioroebe/gui/jruby/aminoacid_composition/aminoacid_composition.rb +0 -166
  398. data/lib/bioroebe/gui/jruby/blosum_matrix_viewer/blosum_matrix_viewer.rb +0 -82
  399. data/lib/bioroebe/gui/libui/README.md +0 -4
  400. data/lib/bioroebe/gui/libui/alignment/alignment.rb +0 -116
  401. data/lib/bioroebe/gui/libui/blosum_matrix_viewer/blosum_matrix_viewer.rb +0 -112
  402. data/lib/bioroebe/gui/libui/calculate_cell_numbers_of_bacteria/calculate_cell_numbers_of_bacteria.rb +0 -60
  403. data/lib/bioroebe/gui/libui/controller/controller.rb +0 -116
  404. data/lib/bioroebe/gui/libui/dna_to_aminoacid_widget/dna_to_aminoacid_widget.rb +0 -161
  405. data/lib/bioroebe/gui/libui/dna_to_reverse_complement_widget/dna_to_reverse_complement_widget.rb +0 -76
  406. data/lib/bioroebe/gui/libui/hamming_distance/hamming_distance.rb +0 -135
  407. data/lib/bioroebe/gui/libui/levensthein_distance/levensthein_distance.rb +0 -118
  408. data/lib/bioroebe/gui/libui/protein_to_DNA/protein_to_DNA.rb +0 -115
  409. data/lib/bioroebe/gui/libui/random_sequence/random_sequence.rb +0 -190
  410. data/lib/bioroebe/gui/libui/show_codon_table/show_codon_table.rb +0 -134
  411. data/lib/bioroebe/gui/libui/show_codon_usage/show_codon_usage.rb +0 -89
  412. data/lib/bioroebe/gui/libui/three_to_one/three_to_one.rb +0 -113
  413. data/lib/bioroebe/gui/shared_code/alignment/alignment_module.rb +0 -102
  414. data/lib/bioroebe/gui/shared_code/aminoacid_composition/aminoacid_composition_module.rb +0 -94
  415. data/lib/bioroebe/gui/shared_code/calculate_cell_numbers_of_bacteria/calculate_cell_numbers_of_bacteria_module.rb +0 -216
  416. data/lib/bioroebe/gui/shared_code/protein_to_DNA/protein_to_DNA_module.rb +0 -192
  417. data/lib/bioroebe/gui/shared_code/show_codon_table/show_codon_table_module.rb +0 -72
  418. data/lib/bioroebe/gui/tk/aminoacid_composition/aminoacid_composition.rb +0 -206
  419. data/lib/bioroebe/gui/tk/blosum_matrix_viewer/blosum_matrix_viewer.rb +0 -140
  420. data/lib/bioroebe/gui/tk/hamming_distance/hamming_distance.rb +0 -262
  421. data/lib/bioroebe/gui/tk/levensthein_distance/levensthein_distance.rb +0 -243
  422. data/lib/bioroebe/gui/tk/three_to_one/three_to_one.rb +0 -199
  423. data/lib/bioroebe/gui/unified_widgets/anti_sense_strand/anti_sense_strand.rb +0 -519
  424. data/lib/bioroebe/shell/colours/colours.rb +0 -235
  425. data/lib/bioroebe/shell/help/help.rb +0 -25
  426. data/lib/bioroebe/shell/misc.rb +0 -10227
  427. data/lib/bioroebe/toplevel_methods/ad_hoc_task.rb +0 -56
  428. data/lib/bioroebe/toplevel_methods/aminoacids_and_proteins.rb +0 -722
  429. data/lib/bioroebe/toplevel_methods/atomic_composition.rb +0 -198
  430. data/lib/bioroebe/toplevel_methods/base_composition.rb +0 -121
  431. data/lib/bioroebe/toplevel_methods/blast.rb +0 -153
  432. data/lib/bioroebe/toplevel_methods/calculate_n50_value.rb +0 -57
  433. data/lib/bioroebe/toplevel_methods/cat.rb +0 -71
  434. data/lib/bioroebe/toplevel_methods/chunked_display.rb +0 -92
  435. data/lib/bioroebe/toplevel_methods/cliner.rb +0 -81
  436. data/lib/bioroebe/toplevel_methods/complement.rb +0 -58
  437. data/lib/bioroebe/toplevel_methods/convert_global_env.rb +0 -39
  438. data/lib/bioroebe/toplevel_methods/databases.rb +0 -73
  439. data/lib/bioroebe/toplevel_methods/delimiter.rb +0 -19
  440. data/lib/bioroebe/toplevel_methods/digest.rb +0 -81
  441. data/lib/bioroebe/toplevel_methods/download_and_fetch_data.rb +0 -146
  442. data/lib/bioroebe/toplevel_methods/e.rb +0 -20
  443. data/lib/bioroebe/toplevel_methods/editor.rb +0 -21
  444. data/lib/bioroebe/toplevel_methods/esystem.rb +0 -22
  445. data/lib/bioroebe/toplevel_methods/exponential_growth.rb +0 -74
  446. data/lib/bioroebe/toplevel_methods/extract.rb +0 -56
  447. data/lib/bioroebe/toplevel_methods/file_and_directory_related_actions.rb +0 -269
  448. data/lib/bioroebe/toplevel_methods/frequencies.rb +0 -99
  449. data/lib/bioroebe/toplevel_methods/hamming_distance.rb +0 -60
  450. data/lib/bioroebe/toplevel_methods/infer.rb +0 -66
  451. data/lib/bioroebe/toplevel_methods/leading_five_prime_and_trailing_three_prime.rb +0 -101
  452. data/lib/bioroebe/toplevel_methods/levensthein.rb +0 -63
  453. data/lib/bioroebe/toplevel_methods/log_directory.rb +0 -109
  454. data/lib/bioroebe/toplevel_methods/longest_common_substring.rb +0 -55
  455. data/lib/bioroebe/toplevel_methods/map_ncbi_entry_to_eutils_id.rb +0 -88
  456. data/lib/bioroebe/toplevel_methods/matches.rb +0 -259
  457. data/lib/bioroebe/toplevel_methods/misc.rb +0 -596
  458. data/lib/bioroebe/toplevel_methods/nucleotides.rb +0 -787
  459. data/lib/bioroebe/toplevel_methods/number_of_clones.rb +0 -63
  460. data/lib/bioroebe/toplevel_methods/open_in_browser.rb +0 -79
  461. data/lib/bioroebe/toplevel_methods/open_reading_frames.rb +0 -236
  462. data/lib/bioroebe/toplevel_methods/opn.rb +0 -34
  463. data/lib/bioroebe/toplevel_methods/palindromes.rb +0 -155
  464. data/lib/bioroebe/toplevel_methods/parse.rb +0 -59
  465. data/lib/bioroebe/toplevel_methods/phred_error_probability.rb +0 -68
  466. data/lib/bioroebe/toplevel_methods/rds.rb +0 -24
  467. data/lib/bioroebe/toplevel_methods/remove.rb +0 -86
  468. data/lib/bioroebe/toplevel_methods/return_source_code_of_this_method.rb +0 -35
  469. data/lib/bioroebe/toplevel_methods/return_subsequence_based_on_indices.rb +0 -68
  470. data/lib/bioroebe/toplevel_methods/rna_splicing.rb +0 -73
  471. data/lib/bioroebe/toplevel_methods/rnalfold.rb +0 -69
  472. data/lib/bioroebe/toplevel_methods/searching_and_finding.rb +0 -116
  473. data/lib/bioroebe/toplevel_methods/shuffleseq.rb +0 -37
  474. data/lib/bioroebe/toplevel_methods/statistics.rb +0 -53
  475. data/lib/bioroebe/toplevel_methods/sum_of_odd_integers.rb +0 -62
  476. data/lib/bioroebe/toplevel_methods/three_delimiter.rb +0 -34
  477. data/lib/bioroebe/toplevel_methods/time_and_date.rb +0 -53
  478. data/lib/bioroebe/toplevel_methods/to_camelcase.rb +0 -31
  479. data/lib/bioroebe/toplevel_methods/truncate.rb +0 -48
  480. data/lib/bioroebe/toplevel_methods/url.rb +0 -36
  481. data/lib/bioroebe/toplevel_methods/verbose.rb +0 -59
  482. data/lib/bioroebe/utility_scripts/showorf/constants.rb +0 -31
  483. data/lib/bioroebe/utility_scripts/showorf/help.rb +0 -33
  484. data/lib/bioroebe/utility_scripts/showorf/initialize.rb +0 -52
  485. data/lib/bioroebe/utility_scripts/showorf/menu.rb +0 -68
  486. data/lib/bioroebe/utility_scripts/showorf/reset.rb +0 -36
  487. data/lib/bioroebe/utility_scripts/showorf/run.rb +0 -152
  488. data/lib/bioroebe/utility_scripts/showorf/show.rb +0 -97
  489. /data/doc/{german_names_for_the_aminoacids.md → german_names_for_the_aminoacids/german_names_for_the_aminoacids.md} +0 -0
  490. /data/doc/{pdb_ATOM_entry.md → pdb_ATOM_entry/pdb_ATOM_entry.md} +0 -0
  491. /data/doc/{resources.md → resources/resources.md} +0 -0
  492. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/aminoacid_composition/customized_dialog.rb +0 -0
  493. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/anti_sense_strand/anti_sense_strand.config +0 -0
  494. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/calculate_cell_numbers_of_bacteria/calculate_cell_numbers_of_bacteria.config +0 -0
  495. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/dna_to_reverse_complement_widget/dna_to_reverse_complement_widget.config +0 -0
  496. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/hamming_distance/hamming_distance.config +0 -0
  497. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/levensthein_distance/levensthein_distance.config +0 -0
  498. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/protein_to_DNA/protein_to_DNA.config +0 -0
  499. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/restriction_enzymes/restriction_enzymes.config +0 -0
  500. /data/lib/bioroebe/gui/{gtk3 → universal_widgets}/www_finder/www_finder.config +0 -0
  501. /data/lib/bioroebe/yaml/{base_composition_of_dna.yml → base_composition_of_dna/base_composition_of_dna.yml} +0 -0
  502. /data/lib/bioroebe/yaml/{nuclear_localization_sequences.yml → nuclear_localization_sequences/nuclear_localization_sequences.yml} +0 -0
  503. /data/lib/bioroebe/yaml/{talens.yml → talens/talens.yml} +0 -0
@@ -0,0 +1,557 @@
1
+ #!/usr/bin/ruby -w
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+ # Encoding: UTF-8
3
+ # frozen_string_literal: true
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+ # =========================================================================== #
5
+ # === Bioroebe::GUI::UniversalWidgets::Alignment
6
+ #
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+ #
8
+ # Usage example:
9
+ #
10
+ # Bioroebe::GUI::UniversalWidgets::Alignment.new(ARGV)
11
+ #
12
+ # =========================================================================== #
13
+ # require 'bioroebe/gui/universal_widgets/alignment/alignment.rb'
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+ # =========================================================================== #
15
+ require 'universal_widgets/base/base.rb'
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+
17
+ module Bioroebe
18
+
19
+ module GUI
20
+
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+ module UniversalWidgets
22
+
23
+ class Alignment < ::UniversalWidgets::Base # === Bioroebe::GUI::UniversalWidgets::Alignment
24
+
25
+ require 'bioroebe/base/commandline_application/commandline_arguments.rb'
26
+ include ::Bioroebe::CommandlineArguments
27
+
28
+ require 'bioroebe/constants/GUIs.rb'
29
+ require 'bioroebe/toplevel_methods/toplevel_methods.rb'
30
+ require 'bioroebe/sequence/alignment.rb'
31
+
32
+ # ========================================================================= #
33
+ # === TITLE
34
+ # ========================================================================= #
35
+ TITLE = 'Alignment'
36
+
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+ # ========================================================================= #
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+ # === WIDTH
39
+ # ========================================================================= #
40
+ WIDTH = '65% or 500px minimum'
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+
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+ # ========================================================================= #
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+ # === HEIGHT
44
+ # ========================================================================= #
45
+ HEIGHT = '55% or 300px minimum'
46
+
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+ # ========================================================================= #
48
+ # === USE_THIS_FONT
49
+ # ========================================================================= #
50
+ USE_THIS_FONT = :hack_26
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+
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+ # ========================================================================= #
53
+ # === FONT_FOR_THE_ENTRIES
54
+ #
55
+ # The entries must use a mono-spaced font.
56
+ # ========================================================================= #
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+ FONT_FOR_THE_ENTRIES = :hack_22
58
+
59
+ # ========================================================================= #
60
+ # === TEXT_INPUT_THE_SEQUENCES
61
+ # ========================================================================= #
62
+ TEXT_INPUT_THE_SEQUENCES = 'Input the sequences that you wish '\
63
+ 'to compare to one another'
64
+
65
+ # ========================================================================= #
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+ # === TOOLTIP_HINT_FOR_THE_DO_ANALYSE_BUTTON
67
+ # ========================================================================= #
68
+ TOOLTIP_HINT_FOR_THE_DO_ANALYSE_BUTTON =
69
+ "Click on this button to analyse the given sequence. Make sure "\
70
+ "to use <b>newlines</b> in order to split the sequence at hand."
71
+
72
+ # ========================================================================= #
73
+ # === TOOLTIP_HINT_FOR_THE_ENTRY_CONSENSUS_SEQUENCE
74
+ #
75
+ # This is the base-tooltip for the entry that retains our consensus
76
+ # sequence.
77
+ # ========================================================================= #
78
+ TOOLTIP_HINT_FOR_THE_ENTRY_CONSENSUS_SEQUENCE =
79
+ 'This entry will contain the <b>consensus sequence</b>, '\
80
+ 'derived from the above sequences.'
81
+
82
+ # ========================================================================= #
83
+ # === TOOLTIP_HINT_FOR_THE_ENTRY_CONSENSUS_SEQUENCE_TRAILING_INFORMATION
84
+ # ========================================================================= #
85
+ TOOLTIP_HINT_FOR_THE_ENTRY_CONSENSUS_SEQUENCE_TRAILING_INFORMATION =
86
+ "\n\nTake note that in the event that there is <b>an even number of "\
87
+ "input sequences</b>, the entries defined before will take precedence. "\
88
+ "So, for instance, if you have four sequences in total, where two are "\
89
+ "ATTA and the next two are ATTT, then the consensus sequence is "\
90
+ "currently assumed to be <b>ATTA</b>."
91
+
92
+ # ========================================================================= #
93
+ # === initialize
94
+ # ========================================================================= #
95
+ def initialize(
96
+ commandline_arguments = nil,
97
+ run_already = true
98
+ )
99
+ determine_the_GUI_to_be_used(commandline_arguments)
100
+ reset
101
+ set_commandline_arguments(
102
+ commandline_arguments
103
+ )
104
+ run if run_already
105
+ end
106
+
107
+ # ========================================================================= #
108
+ # === reset (reset tag)
109
+ # ========================================================================= #
110
+ def reset
111
+ super() if respond_to?(:super)
112
+ reset_the_internal_variables
113
+ reset_the_base_module # This must come after reset_the_internal_variables().
114
+ infer_the_namespace
115
+ # ======================================================================= #
116
+ # === @configuration
117
+ # ======================================================================= #
118
+ @configuration = [true, __dir__, namespace?]
119
+ # ======================================================================= #
120
+ # === Set the title, width, height and the font in use.
121
+ # ======================================================================= #
122
+ title_width_height_font(TITLE, WIDTH, HEIGHT, USE_THIS_FONT)
123
+ handle_CSS if use_gtk3?
124
+ reset_the_alignment_object
125
+ end
126
+
127
+ # ========================================================================= #
128
+ # === handle_CSS_rules (CSS tag)
129
+ # ========================================================================= #
130
+ def handle_CSS_rules
131
+ use_gtk_paradise_project_css_file
132
+ append_project_css_file
133
+ apply_the_CSS_rules
134
+ end; alias handle_CSS handle_CSS_rules # === handle_CSS
135
+
136
+ # ========================================================================= #
137
+ # === return_the_first_row
138
+ # ========================================================================= #
139
+ def return_the_first_row
140
+ _ = create_hbox
141
+ top_label = left_aligned_label(
142
+ TEXT_INPUT_THE_SEQUENCES
143
+ )
144
+ top_label.make_selectable
145
+ top_label.center
146
+ _.minimal(top_label)
147
+ use_this_image = image_document_open
148
+ if use_this_image
149
+ event_box = event_box(use_this_image)
150
+ if event_box
151
+ event_box.hint = 'Click on this icon to open a local file.'
152
+ event_box.on_clicked {
153
+ do_open_and_assign_a_local_file
154
+ }
155
+ _.pack_end(event_box)
156
+ end
157
+ end
158
+ return _
159
+ end
160
+
161
+ # ========================================================================= #
162
+ # === create_the_entries (entry tag, entries tag)
163
+ # ========================================================================= #
164
+ def create_the_entries
165
+ create_the_consensus_sequence_entry
166
+ # ======================================================================= #
167
+ # === @entry_numbers
168
+ # ======================================================================= #
169
+ @entry_numbers = create_entry
170
+ @entry_numbers.bblack1
171
+ @entry_numbers.use_this_font = FONT_FOR_THE_ENTRIES
172
+ @entry_numbers.hint =
173
+ 'This area may indicate the numbers for '\
174
+ 'the alignment shown right above.'
175
+ @entry_numbers.very_light_yellow_background
176
+ end
177
+
178
+ # ========================================================================= #
179
+ # === create_the_text_buffer_and_the_text_view
180
+ # ========================================================================= #
181
+ def create_the_text_buffer_and_the_text_view
182
+ # ======================================================================= #
183
+ # === @text_buffer
184
+ # ======================================================================= #
185
+ @text_buffer = create_text_buffer
186
+ # ======================================================================= #
187
+ # === @text_view
188
+ # ======================================================================= #
189
+ @text_view = create_text_view(@text_buffer)
190
+ end
191
+
192
+ # ========================================================================= #
193
+ # === textview?
194
+ # ========================================================================= #
195
+ def textview?
196
+ @text_view
197
+ end
198
+
199
+ # ========================================================================= #
200
+ # === create_the_scrolled_window
201
+ # ========================================================================= #
202
+ def create_the_scrolled_window
203
+ # ======================================================================= #
204
+ # === @scrolled_window
205
+ # ======================================================================= #
206
+ @scrolled_window = create_scrolled_window(@text_view)
207
+ @scrolled_window.width_height(300, 400)
208
+ @scrolled_window.pad4px
209
+ @scrolled_window.bblack2
210
+ end
211
+
212
+ # ========================================================================= #
213
+ # === padding?
214
+ # ========================================================================= #
215
+ def padding?
216
+ 12
217
+ end
218
+
219
+ # ========================================================================= #
220
+ # === border_size?
221
+ # ========================================================================= #
222
+ def border_size?
223
+ 8
224
+ end
225
+
226
+ # ========================================================================= #
227
+ # === smaller_font?
228
+ # ========================================================================= #
229
+ def smaller_font?
230
+ SMALLER_FONT
231
+ end
232
+
233
+ # ========================================================================= #
234
+ # === the_do_analyse_button_was_clicked
235
+ # ========================================================================= #
236
+ def the_do_analyse_button_was_clicked
237
+ do_analyse
238
+ realign_the_numbers_showing_how_long_the_consensus_sequence_is
239
+ update_the_hint_for_the_entry_consequences_sequence(
240
+ (
241
+ "This entry will contain the consensus sequence, "\
242
+ "derived from the above "+
243
+ (@text_buffer.text?.count("\n")+1).to_s+" sequences.\n\nNote "\
244
+ "that only the minimal length will be compared - "\
245
+ "superfluous nucleotides will NOT be considered unless "\
246
+ "they can be aligned to other sequences."+
247
+ TOOLTIP_HINT_FOR_THE_ENTRY_CONSENSUS_SEQUENCE_TRAILING_INFORMATION
248
+ ).squeeze(' ')
249
+ )
250
+ end
251
+
252
+ # ========================================================================= #
253
+ # === create_the_skeleton (create tag, skeleton tag)
254
+ # ========================================================================= #
255
+ def create_the_skeleton
256
+ create_the_checkboxes # Create the checkboxes first.
257
+ create_the_entries
258
+ create_the_buttons
259
+ create_the_text_buffer_and_the_text_view
260
+ create_the_scrolled_window
261
+ end
262
+
263
+ # ========================================================================= #
264
+ # === create_the_checkboxes
265
+ # ========================================================================= #
266
+ def create_the_checkboxes
267
+ # ======================================================================= #
268
+ # === @checkbox1
269
+ # ======================================================================= #
270
+ @checkbox1 = create_checkbox
271
+ @checkbox1.is_active
272
+ @checkbox2 = create_checkbox
273
+ end
274
+
275
+ # ========================================================================= #
276
+ # === button_convert?
277
+ # ========================================================================= #
278
+ def button_convert?
279
+ @button_convert
280
+ end
281
+
282
+
283
+ # ========================================================================= #
284
+ # === create_the_buttons (buttons tag)
285
+ # ========================================================================= #
286
+ def create_the_buttons
287
+ # ======================================================================= #
288
+ # === @button_do_analyse
289
+ # ======================================================================= #
290
+ @button_do_analyse = bold_button('_Do analyse', self, :use_mnemonic) {
291
+ :the_do_analyse_button_was_clicked
292
+ }
293
+ @button_do_analyse.clear_background
294
+ @button_do_analyse.bblack1
295
+ @button_do_analyse.on_hover(:lightblue)
296
+ @button_do_analyse.hint = TOOLTIP_HINT_FOR_THE_DO_ANALYSE_BUTTON
297
+ end
298
+
299
+ # ========================================================================= #
300
+ # === do_trigger_the_conversion (conversion tag)
301
+ #
302
+ # This method is the one that will convert from the three-letter to the
303
+ # one-letter and vice versa.
304
+ # ========================================================================= #
305
+ def do_trigger_the_conversion(
306
+ i = @entry1.text?,
307
+ checkbox1 = @checkbox1
308
+ )
309
+ i = i.to_s.dup.delete(' ')
310
+ if checkbox1.active?
311
+ new_result = Bioroebe.three_to_one(i).to_s
312
+ else
313
+ new_result = Bioroebe.one_to_three(i).to_s
314
+ end
315
+ if new_result and !new_result.empty?
316
+ @entry2.set_text(new_result)
317
+ @entry2.make_bold
318
+ end
319
+ end; alias do_the_conversion do_trigger_the_conversion # === do_the_conversion
320
+
321
+ # ========================================================================= #
322
+ # === return_the_checkbox_widget
323
+ # ========================================================================= #
324
+ def return_the_checkbox_widget
325
+ smaller_font = smaller_font?
326
+ grid = default_grid
327
+ text1 = text('3-to-1 conversion')
328
+ text1.use_this_font(smaller_font)
329
+ text1.hint = 'Convert the three letter code to the one letter code.'
330
+ pp text1
331
+ grid.left(text1)
332
+ grid.right(@checkbox1)
333
+ text2 = text('1-to-3 conversion')
334
+ text2.use_this_font(smaller_font)
335
+ text2.hint = 'Convert the one letter code to the three letter code.'
336
+ grid.left(text2)
337
+ grid.right(@checkbox2)
338
+ @checkbox1.on_toggled {
339
+ if @checkbox1.active? == false
340
+ @checkbox2.is_now_active
341
+ else
342
+ @checkbox2.is_now_inactive
343
+ end
344
+ }
345
+ @checkbox2.on_toggled {
346
+ if @checkbox2.active? == false
347
+ @checkbox1.is_now_active
348
+ else
349
+ @checkbox1.is_now_inactive
350
+ end
351
+ }
352
+ return grid
353
+ end
354
+
355
+ # ========================================================================= #
356
+ # === do_analyse
357
+ #
358
+ # This method will be called whenever the user hits the "Do analyse"
359
+ # button.
360
+ # ========================================================================= #
361
+ def do_analyse(
362
+ _ = text_buffer?.text?
363
+ )
364
+ if _ and !_.empty?
365
+ _.strip!
366
+ alignment?.use_this_as_input(_)
367
+ consensus_sequence = return_the_consensus_sequence
368
+ @entry_consensus_sequence.set_text(consensus_sequence)
369
+ else
370
+ pop_up_widget(
371
+ over_this_widget: text_view_widget?,
372
+ text: 'Please assign a sequence first.'
373
+ )
374
+ end
375
+ end; alias do_analyse_again do_analyse # === do_analyse_again
376
+
377
+ # ========================================================================= #
378
+ # === run (run tag)
379
+ # ========================================================================= #
380
+ def run
381
+ run_super
382
+ end
383
+
384
+ # ========================================================================= #
385
+ # === return_the_consensus_sequence
386
+ # ========================================================================= #
387
+ def return_the_consensus_sequence
388
+ @alignment.consensus_sequence?
389
+ end
390
+
391
+ # ========================================================================= #
392
+ # === text_view_widget?
393
+ # ========================================================================= #
394
+ def text_view_widget?
395
+ @text_view
396
+ end
397
+
398
+ # ========================================================================= #
399
+ # === realign_the_numbers_showing_how_long_the_consensus_sequence_is
400
+ # ========================================================================= #
401
+ def realign_the_numbers_showing_how_long_the_consensus_sequence_is
402
+ @entry_numbers.center if @entry_numbers.respond_to?(:center)
403
+ n_characters = @entry_consensus_sequence.text?.size
404
+ @entry_numbers.set_text(return_fill_up_to(n_characters))
405
+ end
406
+
407
+ # ========================================================================= #
408
+ # === create_the_consensus_sequence_entry
409
+ # ========================================================================= #
410
+ def create_the_consensus_sequence_entry
411
+ # ======================================================================= #
412
+ # === @entry_consensus_sequence
413
+ # ======================================================================= #
414
+ @entry_consensus_sequence = entry
415
+ @entry_consensus_sequence.bblack1
416
+ @entry_consensus_sequence.center
417
+ @entry_consensus_sequence.use_this_font = FONT_FOR_THE_ENTRIES
418
+ @entry_consensus_sequence.yellow_background
419
+ update_the_hint_for_the_entry_consequences_sequence(
420
+ TOOLTIP_HINT_FOR_THE_ENTRY_CONSENSUS_SEQUENCE+
421
+ TOOLTIP_HINT_FOR_THE_ENTRY_CONSENSUS_SEQUENCE_TRAILING_INFORMATION
422
+ )
423
+ end
424
+
425
+ # ========================================================================= #
426
+ # === entry_consensus_sequence?
427
+ # ========================================================================= #
428
+ def entry_consensus_sequence?
429
+ @entry_consensus_sequence
430
+ end
431
+
432
+ # ========================================================================= #
433
+ # === return_fill_up_to
434
+ # ========================================================================= #
435
+ def return_fill_up_to(i)
436
+ _ = ''.dup
437
+ i.times {|counter|
438
+ counter = (counter+1) % 10
439
+ _ << counter.to_s
440
+ }
441
+ return _
442
+ end
443
+
444
+ # ========================================================================= #
445
+ # === do_open_and_assign_a_local_file
446
+ # ========================================================================= #
447
+ def do_open_and_assign_a_local_file
448
+ open_local_file {{
449
+ start_directory: log_dir?,
450
+ additional_folders: [
451
+ log_dir?,
452
+ '/Depot/j/',
453
+ '/Depot/jj/',
454
+ '/Depot/jjj/',
455
+ '/Depot/jjjj/'
456
+ ]
457
+ }}
458
+ _ = main_file?
459
+ if _ and File.exist?(_)
460
+ dataset = File.read(_)
461
+ @text_buffer.set_text(dataset)
462
+ do_analyse_again
463
+ end
464
+ end
465
+
466
+ # ========================================================================= #
467
+ # === update_the_hint_for_the_entry_consequences_sequence
468
+ # ========================================================================= #
469
+ def update_the_hint_for_the_entry_consequences_sequence(
470
+ i = ''
471
+ )
472
+ @entry_consensus_sequence.hint = i
473
+ end
474
+
475
+ # ========================================================================= #
476
+ # === alignment?
477
+ # ========================================================================= #
478
+ def alignment?
479
+ @alignment
480
+ end
481
+
482
+ # ========================================================================= #
483
+ # === text_buffer?
484
+ # ========================================================================= #
485
+ def text_buffer?
486
+ @text_buffer
487
+ end
488
+
489
+ # ========================================================================= #
490
+ # === reset_the_alignment_object
491
+ # ========================================================================= #
492
+ def reset_the_alignment_object
493
+ # ======================================================================= #
494
+ # === @alignment
495
+ # ======================================================================= #
496
+ @alignment = Bioroebe::Alignment.new(nil, :do_not_run_yet)
497
+ end
498
+
499
+ # ========================================================================= #
500
+ # === Bioroebe::GUI::UniversalWidgets::Alignment[]
501
+ # ========================================================================= #
502
+ def self.[](i = ARGV)
503
+ new(i)
504
+ end
505
+
506
+ # ========================================================================= #
507
+ # === Bioroebe::GUI::Gtk::Alignment.run
508
+ # ========================================================================= #
509
+ def self.run(
510
+ i = ARGV
511
+ )
512
+ ::Gtk.gtk_runner_factory(
513
+ ::Bioroebe::GUI::Gtk::Alignment.new(i)
514
+ )
515
+ end
516
+
517
+ # ========================================================================= #
518
+ # === connect_the_skeleton (connect tag, skeleton tag)
519
+ # ========================================================================= #
520
+ def connect_the_skeleton
521
+ abort_on_exception
522
+
523
+ grid = default_grid
524
+ grid.full_row(return_the_first_row)
525
+ grid.full_row(@scrolled_window)
526
+ grid.full_row(@entry_consensus_sequence)
527
+ grid.full_row(@entry_numbers)
528
+ grid.full_row(@button_do_analyse)
529
+ grid.hcenter
530
+
531
+ window = runner_widget(nil, width?, height?, title?)
532
+ window << grid
533
+ do_focus_on_the_textview
534
+ ::UniversalWidgets.set_main_window(window)
535
+ upon_delete_event_quit_the_application
536
+ window.use_this_font = font?
537
+ window.show_all
538
+ window.set_size_request(width?, height?)
539
+ window.set_default_size(width?, height?)
540
+ window.set_padding(padding?)
541
+ window.set_border_size(border_size?)
542
+ window.top_left
543
+ run_main
544
+ end
545
+
546
+ # ========================================================================= #
547
+ # === do_focus_on_the_textview
548
+ # ========================================================================= #
549
+ def do_focus_on_the_textview
550
+ textview?.do_focus
551
+ end
552
+
553
+ end; end; end; end
554
+
555
+ if __FILE__ == $PROGRAM_NAME
556
+ Bioroebe::GUI::UniversalWidgets::Alignment.new(ARGV)
557
+ end # gui_alignment