partis-bcr 1.0.13.post1.dev3__cp312-cp312-macosx_10_13_universal2.whl → 1.0.13.post1.dev4__cp312-cp312-macosx_10_13_universal2.whl

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (49) hide show
  1. {partis_bcr-1.0.13.post1.dev3.dist-info → partis_bcr-1.0.13.post1.dev4.dist-info}/METADATA +1 -1
  2. {partis_bcr-1.0.13.post1.dev3.dist-info → partis_bcr-1.0.13.post1.dev4.dist-info}/RECORD +49 -49
  3. test/new-results/partition-new-simu/fasttree/iclust-0/log +3 -3
  4. test/new-results/run-times.csv +7 -7
  5. test/new-results/test.log +40 -39
  6. test/paired/new-results/partition-new-simu/fasttree/iclust-0/log +3 -3
  7. test/paired/new-results/partition-new-simu/fasttree/iclust-1/log +3 -3
  8. test/paired/new-results/partition-new-simu/fasttree/iclust-2/log +2 -2
  9. test/paired/new-results/partition-new-simu/igh+igk/partition-igh/fasttree/iclust-0/log +6 -6
  10. test/paired/new-results/partition-new-simu/igh+igk/partition-igh/fasttree/iclust-1/log +4 -4
  11. test/paired/new-results/partition-new-simu/igh+igk/partition-igk/fasttree/iclust-1/log +1 -1
  12. test/paired/new-results/partition-new-simu/igh+igl/partition-igh/fasttree/iclust-0/log +2 -2
  13. test/paired/new-results/partition-new-simu/igh+igl/partition-igl/fasttree/iclust-0/log +1 -1
  14. test/paired/new-results/partition-new-simu-annotation-performance/plots/flcount-matrix.svg +107 -107
  15. test/paired/new-results/partition-new-simu-annotation-performance/plots/func-non-func-per-drop-log.svg +83 -83
  16. test/paired/new-results/partition-new-simu-annotation-performance/plots/func-non-func-per-drop.svg +61 -61
  17. test/paired/new-results/partition-new-simu-annotation-performance/plots/paired-seqs-per-seq-after.svg +18 -18
  18. test/paired/new-results/partition-new-simu-annotation-performance/plots/paired-seqs-per-seq-before.svg +24 -24
  19. test/paired/new-results/partition-new-simu-annotation-performance/plots/pseq-matrix.svg +35 -35
  20. test/paired/new-results/partition-new-simu-annotation-performance/plots/seqs-per-droplet.svg +22 -22
  21. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance-correct-family.svg +45 -45
  22. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance-correct.svg +45 -45
  23. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance-mispaired.svg +45 -45
  24. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance-multiple.svg +15 -15
  25. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance-near-family.svg +15 -15
  26. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance-total.svg +47 -47
  27. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance-unpaired.svg +48 -48
  28. test/paired/new-results/partition-new-simu-annotation-performance/plots/true-pair-clean-performance.svg +27 -27
  29. test/paired/new-results/run-times.csv +6 -6
  30. test/paired/new-results/subset-partition-new-simu/isub-0/partition.log +59 -59
  31. test/paired/new-results/subset-partition-new-simu/isub-1/partition.log +67 -66
  32. test/paired/new-results/subset-partition-new-simu/merged-partition.log +37 -37
  33. test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igh/sw-cache.yaml +1 -1
  34. test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igk/sw-cache.yaml +1 -1
  35. test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igl/sw-cache.yaml +1 -1
  36. test/paired/new-results/test.log +136 -136
  37. {partis_bcr-1.0.13.post1.dev3.data → partis_bcr-1.0.13.post1.dev4.data}/scripts/cf-alleles.py +0 -0
  38. {partis_bcr-1.0.13.post1.dev3.data → partis_bcr-1.0.13.post1.dev4.data}/scripts/cf-germlines.py +0 -0
  39. {partis_bcr-1.0.13.post1.dev3.data → partis_bcr-1.0.13.post1.dev4.data}/scripts/compare-plotdirs.py +0 -0
  40. {partis_bcr-1.0.13.post1.dev3.data → partis_bcr-1.0.13.post1.dev4.data}/scripts/extract-pairing-info.py +0 -0
  41. {partis_bcr-1.0.13.post1.dev3.data → partis_bcr-1.0.13.post1.dev4.data}/scripts/gctree-run.py +0 -0
  42. {partis_bcr-1.0.13.post1.dev3.data → partis_bcr-1.0.13.post1.dev4.data}/scripts/get-naive-probabilities.py +0 -0
  43. {partis_bcr-1.0.13.post1.dev3.data → partis_bcr-1.0.13.post1.dev4.data}/scripts/parse-output.py +0 -0
  44. {partis_bcr-1.0.13.post1.dev3.data → partis_bcr-1.0.13.post1.dev4.data}/scripts/partis-test.py +0 -0
  45. {partis_bcr-1.0.13.post1.dev3.data → partis_bcr-1.0.13.post1.dev4.data}/scripts/split-loci.py +0 -0
  46. {partis_bcr-1.0.13.post1.dev3.dist-info → partis_bcr-1.0.13.post1.dev4.dist-info}/WHEEL +0 -0
  47. {partis_bcr-1.0.13.post1.dev3.dist-info → partis_bcr-1.0.13.post1.dev4.dist-info}/entry_points.txt +0 -0
  48. {partis_bcr-1.0.13.post1.dev3.dist-info → partis_bcr-1.0.13.post1.dev4.dist-info}/licenses/COPYING +0 -0
  49. {partis_bcr-1.0.13.post1.dev3.dist-info → partis_bcr-1.0.13.post1.dev4.dist-info}/top_level.txt +0 -0
@@ -36,37 +36,37 @@ writing to paired subdirs
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  run partis cache-parameters --locus igh --dont-write-git-info --max-ccf-fail-frac 0.15 --random-seed 1 --n-procs 10 --input-metafnames test/paired/new-results/subset-partition-new-simu/isub-1/meta.yaml --infname test/paired/new-results/subset-partition-new-simu/isub-1/igh.fa --parameter-dir test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igh --sw-cachefname test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igh/sw-cache.yaml
37
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  --input-metafnames: added meta info for 32 sequences from test/paired/new-results/subset-partition-new-simu/isub-1/meta.yaml: loci paired-uids
38
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  caching parameters
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- vsearch: 32 / 32 v annotations (0 failed) with 8 v genes in 0.1 sec
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+ vsearch: 32 / 32 v annotations (0 failed) with 8 v genes in 0.2 sec
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  keeping 6 / 198 v genes
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  smith-waterman (new-allele fitting)
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- vsearch: 32 / 32 v annotations (0 failed) with 6 v genes in 0.2 sec
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+ vsearch: 32 / 32 v annotations (0 failed) with 6 v genes in 0.1 sec
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  running 10 procs for 32 seqs
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  info for 32 / 32 = 1.000 (removed: 0 failed)
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  kept 14 (0.438) unproductive
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- water time: 0.1 (ig-sw 0.0 processing 0.1)
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+ water time: 0.2 (ig-sw 0.0 processing 0.1)
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  smith-waterman (writing parameters)
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- vsearch: 32 / 32 v annotations (0 failed) with 6 v genes in 0.2 sec
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+ vsearch: 32 / 32 v annotations (0 failed) with 6 v genes in 0.1 sec
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  running 10 procs for 32 seqs
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  info for 32 / 32 = 1.000 (removed: 0 failed)
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  kept 14 (0.438) unproductive
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  writing sw results to test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igh/sw-cache.yaml
53
- writing parameters to test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igh/sw (0.8 sec)
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- water time: 1.0 (ig-sw 0.9 processing 0.1)
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+ writing parameters to test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igh/sw (1.3 sec)
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+ water time: 1.6 (ig-sw 1.5 processing 0.1)
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  writing hmms removed 18 genes from glfo (leaving v 6 d 16 j 4)
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  note: utils.memory_usage_fraction() needs testing on platform 'Darwin' to make sure unit conversions don't need changing
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- (0.7 sec)
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+ (0.9 sec)
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  hmm
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  reading output
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  read 32 hmm output lines with 32 sequences in 32 events (0 failures)
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- writing parameters to test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igh/hmm (0.7 sec)
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- infra time: 0.8
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- hmm step time: 1.4
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+ writing parameters to test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igh/hmm (0.9 sec)
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+ infra time: 1.0
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+ hmm step time: 1.7
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  writing hmms removed 3 genes from glfo (leaving v 6 d 13 j 4)
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  note: utils.memory_usage_fraction() needs testing on platform 'Darwin' to make sure unit conversions don't need changing
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- (0.6 sec)
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- total time: 4.4
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+ (0.9 sec)
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+ total time: 5.9
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  cache-parameters igk:
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  run partis cache-parameters --locus igk --dont-write-git-info --max-ccf-fail-frac 0.15 --random-seed 1 --n-procs 10 --input-metafnames test/paired/new-results/subset-partition-new-simu/isub-1/meta.yaml --infname test/paired/new-results/subset-partition-new-simu/isub-1/igk.fa --parameter-dir test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igk --sw-cachefname test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igk/sw-cache.yaml
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  --input-metafnames: added meta info for 18 sequences from test/paired/new-results/subset-partition-new-simu/isub-1/meta.yaml: loci paired-uids
@@ -86,82 +86,82 @@ smith-waterman (writing parameters)
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  kept 9 (0.500) unproductive
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  writing sw results to test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igk/sw-cache.yaml
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  writing parameters to test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igk/sw (0.7 sec)
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- water time: 0.9 (ig-sw 0.7 processing 0.2)
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+ water time: 1.0 (ig-sw 0.8 processing 0.2)
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  writing hmms removed 2 genes from glfo (leaving v 5 d 1 j 5)
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  note: utils.memory_usage_fraction() needs testing on platform 'Darwin' to make sure unit conversions don't need changing
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- (0.4 sec)
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+ (0.5 sec)
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  hmm
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  reading output
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  read 18 hmm output lines with 18 sequences in 18 events (0 failures)
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- writing parameters to test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igk/hmm (0.6 sec)
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- infra time: 0.7
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- hmm step time: 1.0
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+ writing parameters to test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igk/hmm (0.8 sec)
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+ infra time: 0.9
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+ hmm step time: 1.2
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  writing hmms removed 0 genes from glfo (leaving v 5 d 1 j 5)
101
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102
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  note: utils.memory_usage_fraction() needs testing on platform 'Darwin' to make sure unit conversions don't need changing
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- (0.4 sec)
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- total time: 3.2
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+ (0.5 sec)
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+ total time: 3.7
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  cache-parameters igl:
106
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  run partis cache-parameters --locus igl --dont-write-git-info --max-ccf-fail-frac 0.15 --random-seed 1 --n-procs 10 --input-metafnames test/paired/new-results/subset-partition-new-simu/isub-1/meta.yaml --infname test/paired/new-results/subset-partition-new-simu/isub-1/igl.fa --parameter-dir test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igl --sw-cachefname test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igl/sw-cache.yaml
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  --input-metafnames: added meta info for 11 sequences from test/paired/new-results/subset-partition-new-simu/isub-1/meta.yaml: loci paired-uids
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  caching parameters
109
- vsearch: 11 / 11 v annotations (0 failed) with 3 v genes in 0.2 sec
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+ vsearch: 11 / 11 v annotations (0 failed) with 3 v genes in 0.1 sec
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  keeping 3 / 80 v genes
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  smith-waterman (new-allele fitting)
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  vsearch: 11 / 11 v annotations (0 failed) with 3 v genes in 0.1 sec
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  running 10 procs for 11 seqs
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  info for 11 / 11 = 1.000 (removed: 0 failed)
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  kept 7 (0.636) unproductive
116
- water time: 0.1 (ig-sw 0.0 processing 0.1)
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+ water time: 0.2 (ig-sw 0.0 processing 0.2)
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  smith-waterman (writing parameters)
118
- vsearch: 11 / 11 v annotations (0 failed) with 3 v genes in 0.1 sec
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+ vsearch: 11 / 11 v annotations (0 failed) with 3 v genes in 0.2 sec
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  running 10 procs for 11 seqs
120
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  info for 11 / 11 = 1.000 (removed: 0 failed)
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  kept 7 (0.636) unproductive
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  writing sw results to test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igl/sw-cache.yaml
123
- writing parameters to test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igl/sw (0.4 sec)
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- water time: 0.6 (ig-sw 0.5 processing 0.1)
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+ writing parameters to test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igl/sw (1.0 sec)
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+ water time: 1.2 (ig-sw 1.1 processing 0.2)
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  writing hmms removed 7 genes from glfo (leaving v 3 d 1 j 2)
126
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127
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  note: utils.memory_usage_fraction() needs testing on platform 'Darwin' to make sure unit conversions don't need changing
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- (0.3 sec)
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+ (0.6 sec)
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  hmm
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  reading output
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  read 11 hmm output lines with 11 sequences in 11 events (0 failures)
132
- writing parameters to test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igl/hmm (0.3 sec)
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- infra time: 0.4
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- hmm step time: 0.7
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+ writing parameters to test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igl/hmm (0.6 sec)
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+ infra time: 0.7
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+ hmm step time: 1.0
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  writing hmms removed 0 genes from glfo (leaving v 3 d 1 j 2)
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137
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  note: utils.memory_usage_fraction() needs testing on platform 'Darwin' to make sure unit conversions don't need changing
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- (0.2 sec)
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- total time: 2.3
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+ (0.3 sec)
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+ total time: 3.8
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  partition igh:
141
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  run partis partition --locus igh --dont-write-git-info --max-ccf-fail-frac 0.15 --random-seed 1 --n-procs 10 --input-metafnames test/paired/new-results/subset-partition-new-simu/isub-1/meta.yaml --infname test/paired/new-results/subset-partition-new-simu/isub-1/igh.fa --outfname test/paired/new-results/subset-partition-new-simu/isub-1/single-chain/partition-igh.yaml --refuse-to-cache-parameters --parameter-dir test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igh --sw-cachefname test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igh/sw-cache.yaml
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  --input-metafnames: added meta info for 32 sequences from test/paired/new-results/subset-partition-new-simu/isub-1/meta.yaml: loci paired-uids
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  partitioning (with test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igh/hmm)
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  smith-waterman
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- vsearch: 32 / 32 v annotations (0 failed) with 6 v genes in 0.2 sec
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+ vsearch: 32 / 32 v annotations (0 failed) with 6 v genes in 0.1 sec
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  reading sw results from test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igh/sw-cache.yaml
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  info for 32 / 32 = 1.000 (removed: 0 failed, 0 duplicates [removed when cache file was written])
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  kept 14 (0.438) unproductive
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  water time: 0.0
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  hmm
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- caching all 32 naive sequences (0.6s)
151
+ caching all 32 naive sequences (1.1s)
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  collapsed 32 queries into 30 clusters with identical naive seqs (0.0 sec)
153
- 30 clusters with 10 procs (0.4s)
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+ 30 clusters with 10 procs (0.5s)
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  29 clusters with 7 procs (0.5s)
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- 28 clusters with 5 procs (0.4s)
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- 28 clusters with 3 procs (0.5s)
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- 23 clusters with 2 procs (0.5s)
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- 20 clusters with 1 proc (0.7s)
155
+ 28 clusters with 5 procs (0.6s)
156
+ 28 clusters with 3 procs (0.7s)
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+ 23 clusters with 2 procs (0.8s)
158
+ 20 clusters with 1 proc (0.9s)
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  note not merging entire cpath history
160
- partition loop time: 3.0
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+ partition loop time: 3.9
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  getting annotations for final partition
162
- subcluster annotating 16 clusters with steps: (0.5s) (0.3s)
163
- subcluster annotation time 0.8
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- total time: 4.6
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+ subcluster annotating 16 clusters with steps: (0.8s) (0.2s)
163
+ subcluster annotation time 1.1
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+ total time: 6.3
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  partition igk:
166
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  run partis partition --locus igk --dont-write-git-info --max-ccf-fail-frac 0.15 --random-seed 1 --n-procs 10 --input-metafnames test/paired/new-results/subset-partition-new-simu/isub-1/meta.yaml --infname test/paired/new-results/subset-partition-new-simu/isub-1/igk.fa --outfname test/paired/new-results/subset-partition-new-simu/isub-1/single-chain/partition-igk.yaml --refuse-to-cache-parameters --parameter-dir test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igk --sw-cachefname test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igk/sw-cache.yaml
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  --input-metafnames: added meta info for 18 sequences from test/paired/new-results/subset-partition-new-simu/isub-1/meta.yaml: loci paired-uids
@@ -173,41 +173,41 @@ smith-waterman
173
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  kept 9 (0.500) unproductive
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  water time: 0.0
175
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  hmm
176
- caching all 18 naive sequences (0.3s)
176
+ caching all 18 naive sequences (0.4s)
177
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  collapsed 18 queries into 7 clusters with identical naive seqs (0.0 sec)
178
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  reducing n procs to number of clusters: 10 --> 7
179
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  7 clusters with 7 procs (0.3s)
180
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  7 clusters with 5 procs (0.3s)
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  7 clusters with 3 procs (0.2s)
182
- 6 clusters with 2 procs (0.2s)
183
- 6 clusters with 1 proc (0.3s)
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+ 6 clusters with 2 procs (0.1s)
183
+ 6 clusters with 1 proc (0.4s)
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  partition loop time: 1.3
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  getting annotations for final partition
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- subcluster annotating 6 clusters with steps: (0.3s) (0.1s)
187
- subcluster annotation time 0.4
188
- total time: 2.2
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+ subcluster annotating 6 clusters with steps: (0.4s) (0.1s)
187
+ subcluster annotation time 0.6
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+ total time: 2.5
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  partition igl:
190
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  run partis partition --locus igl --dont-write-git-info --max-ccf-fail-frac 0.15 --random-seed 1 --n-procs 10 --input-metafnames test/paired/new-results/subset-partition-new-simu/isub-1/meta.yaml --infname test/paired/new-results/subset-partition-new-simu/isub-1/igl.fa --outfname test/paired/new-results/subset-partition-new-simu/isub-1/single-chain/partition-igl.yaml --refuse-to-cache-parameters --parameter-dir test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igl --sw-cachefname test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igl/sw-cache.yaml
191
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  --input-metafnames: added meta info for 11 sequences from test/paired/new-results/subset-partition-new-simu/isub-1/meta.yaml: loci paired-uids
192
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  partitioning (with test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igl/hmm)
193
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  smith-waterman
194
- vsearch: 11 / 11 v annotations (0 failed) with 3 v genes in 0.1 sec
194
+ vsearch: 11 / 11 v annotations (0 failed) with 3 v genes in 0.2 sec
195
195
  reading sw results from test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igl/sw-cache.yaml
196
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  info for 11 / 11 = 1.000 (removed: 0 failed, 0 duplicates [removed when cache file was written])
197
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  kept 7 (0.636) unproductive
198
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  water time: 0.0
199
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  hmm
200
- caching all 11 naive sequences (0.2s)
200
+ caching all 11 naive sequences (0.4s)
201
201
  collapsed 11 queries into 3 clusters with identical naive seqs (0.0 sec)
202
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  reducing n procs to number of clusters: 10 --> 3
203
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  3 clusters with 3 procs (0.2s)
204
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  3 clusters with 2 procs (0.2s)
205
- 3 clusters with 1 proc (0.3s)
206
- partition loop time: 0.6
205
+ 3 clusters with 1 proc (0.4s)
206
+ partition loop time: 0.8
207
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  getting annotations for final partition
208
- subcluster annotating 3 clusters with steps: (0.2s) (0.1s)
208
+ subcluster annotating 3 clusters with steps: (0.2s) (0.2s)
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  subcluster annotation time 0.4
210
- total time: 1.4
210
+ total time: 1.7
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  combining chains
212
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  cleaning pair info for 61 seqs
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  synchronized/fixed 0 pairs where one had no pair info after cleaning: h 0 k 0 l 0
@@ -239,9 +239,9 @@ smith-waterman
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  kept 7 (0.368) unproductive
240
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  water time: 0.0
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  hmm
242
- subcluster annotating 11 clusters with steps: (0.4s) (0.2s)
243
- subcluster annotation time 0.6
244
- total time: 0.7
242
+ subcluster annotating 11 clusters with steps: (0.6s) (0.2s)
243
+ subcluster annotation time 0.8
244
+ total time: 0.9
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  need to get annotations for 6/11 joint igk clusters
246
246
  annotate igh+igk: igk
247
247
  run partis annotate --locus igk --dont-write-git-info --max-ccf-fail-frac 0.15 --random-seed 1 --n-procs 10 --input-metafnames test/paired/new-results/subset-partition-new-simu/isub-1/igh+igk/meta-igk.yaml --infname test/paired/new-results/subset-partition-new-simu/isub-1/igh+igk/input-seqs-igk.fa --outfname test/paired/new-results/subset-partition-new-simu/isub-1/igh+igk/partition-igk.yaml --refuse-to-cache-parameters --parameter-dir test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igk --sw-cachefname test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igk/sw-cache.yaml --ignore-sw-pair-info --input-partition-fname test/paired/new-results/subset-partition-new-simu/isub-1/igh+igk/partition-igk-only-partition.yaml
@@ -257,8 +257,9 @@ smith-waterman
257
257
  hmm
258
258
  reading output
259
259
  read 11 hmm output lines with 18 sequences in 11 events (0 failures)
260
- hmm step time: 0.3
261
- total time: 0.4
260
+ infra time: 0.1
261
+ hmm step time: 0.5
262
+ total time: 0.6
262
263
  igh+igl: synchronizing heavy and light chain cluster paths
263
264
  removing badly + unpaired seqs: kept 3 total unpaired (i.e. setting aside in order to reintegrate after paired clustering): h 2 l 1
264
265
  note: discarding unpaired seqs in families with no (well-)paired seqs (i.e. families that are all either unpaired or paired to the other/wrong light chain), rather than keeping track of them to re-add later
@@ -281,15 +282,15 @@ hmm
281
282
  --input-partition-fname: read best partition with 12 sequences in 5 clusters from test/paired/new-results/subset-partition-new-simu/isub-1/igh+igl/partition-igh-only-partition.yaml
282
283
  annotating (with test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igh/hmm)
283
284
  smith-waterman
284
- vsearch: 12 / 12 v annotations (0 failed) with 3 v genes in 0.2 sec
285
+ vsearch: 12 / 12 v annotations (0 failed) with 3 v genes in 0.1 sec
285
286
  reading sw results from test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igh/sw-cache.yaml
286
287
  info for 12 / 12 = 1.000 (removed: 0 failed, 0 duplicates [removed when cache file was written])
287
288
  kept 7 (0.583) unproductive
288
289
  water time: 0.0
289
290
  hmm
290
- subcluster annotating 5 clusters with steps: (0.3s) (0.2s)
291
- subcluster annotation time 0.5
292
- total time: 0.7
291
+ subcluster annotating 5 clusters with steps: (0.4s) (0.3s)
292
+ subcluster annotation time 0.7
293
+ total time: 0.9
293
294
  need to get annotations for 5/5 joint igl clusters
294
295
  annotate igh+igl: igl
295
296
  run partis annotate --locus igl --dont-write-git-info --max-ccf-fail-frac 0.15 --random-seed 1 --n-procs 10 --input-metafnames test/paired/new-results/subset-partition-new-simu/isub-1/igh+igl/meta-igl.yaml --infname test/paired/new-results/subset-partition-new-simu/isub-1/igh+igl/input-seqs-igl.fa --outfname test/paired/new-results/subset-partition-new-simu/isub-1/igh+igl/partition-igl.yaml --refuse-to-cache-parameters --parameter-dir test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igl --sw-cachefname test/paired/new-results/subset-partition-new-simu/isub-1/parameters/igl/sw-cache.yaml --ignore-sw-pair-info --input-partition-fname test/paired/new-results/subset-partition-new-simu/isub-1/igh+igl/partition-igl-only-partition.yaml
@@ -303,9 +304,9 @@ smith-waterman
303
304
  kept 7 (0.636) unproductive
304
305
  water time: 0.0
305
306
  hmm
306
- subcluster annotating 5 clusters with steps: (0.3s) (0.2s)
307
- subcluster annotation time 0.4
308
- total time: 0.6
307
+ subcluster annotating 5 clusters with steps: (0.4s) (0.3s)
308
+ subcluster annotation time 0.6
309
+ total time: 0.7
309
310
  --input-metafnames: no meta info added from test/paired/new-results/subset-partition-new-simu/isub-1/meta.yaml
310
311
  concatenating heavy chain loci:
311
312
  h starting with 11 annotations (19 seqs)
@@ -318,4 +319,4 @@ hmm
318
319
  h 16 --> 16
319
320
  k 6 --> 11 +5
320
321
  l 3 --> 5 +2
321
- total time: 40.2
322
+ total time: 62.1
@@ -17,7 +17,7 @@ partis partition --dont-write-git-info --paired-loci --paired-indir test/paired/
17
17
  removed 3/56 queries from input info that were absent from input partition
18
18
  partitioning (with test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igh/hmm)
19
19
  smith-waterman
20
- vsearch: 53 / 53 v annotations (0 failed) with 6 v genes in 0.2 sec
20
+ vsearch: 53 / 53 v annotations (0 failed) with 6 v genes in 0.1 sec
21
21
  reading sw results from test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igh/sw-cache.yaml
22
22
  info for 53 / 53 = 1.000 (removed: 0 failed, 0 duplicates [removed when cache file was written])
23
23
  kept 24 (0.453) unproductive
@@ -27,16 +27,16 @@ hmm
27
27
  caching input annotation naive seqs in bcrham cache file for 27 clusters (53 seqs)
28
28
  --continue-from-input-partition: using input partition for initial cpath
29
29
  27 clusters (53 seqs)
30
- 27 clusters with 10 procs (0.6s)
31
- 26 clusters with 7 procs (0.5s)
32
- 23 clusters with 5 procs (0.4s)
33
- 22 clusters with 3 procs (0.5s)
34
- 21 clusters with 2 procs (0.5s)
35
- 21 clusters with 1 proc (0.7s)
36
- partition loop time: 3.1
30
+ 27 clusters with 10 procs (0.7s)
31
+ 26 clusters with 7 procs (0.7s)
32
+ 23 clusters with 5 procs (0.6s)
33
+ 22 clusters with 3 procs (0.6s)
34
+ 21 clusters with 2 procs (0.4s)
35
+ 21 clusters with 1 proc (1.1s)
36
+ partition loop time: 4.0
37
37
  getting annotations for final partition
38
- subcluster annotating 18 clusters with steps: (0.7s) (0.3s) (0.3s)
39
- subcluster annotation time 1.3
38
+ subcluster annotating 18 clusters with steps: (1.0s) (0.4s) (0.2s)
39
+ subcluster annotation time 1.7
40
40
  warning added 3 / 56 missing ids as singletons to inferred partition, to match ids in true partition
41
41
  warning added 3 / 56 missing ids as singletons to inferred partition, to match ids in true partition
42
42
  warning added 3 / 56 missing ids as singletons to inferred partition, to match ids in true partition
@@ -47,7 +47,7 @@ getting annotations for final partition
47
47
  warning added 3 / 56 missing ids as singletons to inferred partition, to match ids in true partition
48
48
  warning added 3 / 56 missing ids as singletons to inferred partition, to match ids in true partition
49
49
  warning added 3 / 56 missing ids as singletons to inferred partition, to match ids in true partition
50
- total time: 4.7
50
+ total time: 6.0
51
51
  partition igk:
52
52
  run partis partition --locus igk --dont-write-git-info --max-ccf-fail-frac 0.15 --is-simu --random-seed 1 --n-procs 10 --input-metafnames test/paired/new-results/subset-partition-new-simu/merged-subsets/meta.yaml --input-partition-fname test/paired/new-results/subset-partition-new-simu/merged-subsets/partition-igk.yaml --continue-from-input-partition --parameter-dir test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igk --ignore-sw-pair-info --refuse-to-cache-parameters --ignore-default-input-metafile --infname test/paired/ref-results/test/simu/igk.yaml --outfname test/paired/new-results/subset-partition-new-simu/single-chain/partition-igk.yaml --sw-cachefname test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igk/sw-cache.yaml
53
53
  warning replacing 'paired-uids'/'paired-uids' value for 'bc11af4843-igk' with value from test/paired/new-results/subset-partition-new-simu/merged-subsets/meta.yaml: ['bc11af4843-igh', 'eee6809ad6-igh', 'eee6809ad6-igl'] --> ['eee6809ad6-igh']
@@ -73,18 +73,18 @@ hmm
73
73
  caching input annotation naive seqs in bcrham cache file for 19 clusters (36 seqs)
74
74
  --continue-from-input-partition: using input partition for initial cpath
75
75
  19 clusters (36 seqs)
76
- 19 clusters with 10 procs (0.3s)
76
+ 19 clusters with 10 procs (0.4s)
77
77
  17 clusters with 7 procs (0.3s)
78
78
  15 clusters with 5 procs (0.3s)
79
- 12 clusters with 3 procs (0.3s)
79
+ 12 clusters with 3 procs (0.2s)
80
80
  11 clusters with 2 procs (0.2s)
81
- 7 clusters with 1 proc (0.3s)
81
+ 7 clusters with 1 proc (0.5s)
82
82
  note not merging entire cpath history
83
- partition loop time: 1.7
83
+ partition loop time: 1.9
84
84
  getting annotations for final partition
85
- subcluster annotating 6 clusters with steps: (0.4s) (0.2s) (0.1s)
86
- subcluster annotation time 0.7
87
- total time: 2.7
85
+ subcluster annotating 6 clusters with steps: (0.5s) (0.2s) (0.2s)
86
+ subcluster annotation time 0.9
87
+ total time: 3.1
88
88
  partition igl:
89
89
  run partis partition --locus igl --dont-write-git-info --max-ccf-fail-frac 0.15 --is-simu --random-seed 1 --n-procs 10 --input-metafnames test/paired/new-results/subset-partition-new-simu/merged-subsets/meta.yaml --input-partition-fname test/paired/new-results/subset-partition-new-simu/merged-subsets/partition-igl.yaml --continue-from-input-partition --parameter-dir test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igl --ignore-sw-pair-info --refuse-to-cache-parameters --ignore-default-input-metafile --infname test/paired/ref-results/test/simu/igl.yaml --outfname test/paired/new-results/subset-partition-new-simu/single-chain/partition-igl.yaml --sw-cachefname test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igl/sw-cache.yaml
90
90
  warning replacing 'paired-uids'/'paired-uids' value for '7588f09c07-igl' with value from test/paired/new-results/subset-partition-new-simu/merged-subsets/meta.yaml: ['7588f09c07-igh', 'cb8a759f1a-igh'] --> ['7588f09c07-igh']
@@ -116,20 +116,20 @@ hmm
116
116
  8 clusters with 8 procs (0.2s)
117
117
  8 clusters with 6 procs (0.3s)
118
118
  7 clusters with 4 procs (0.3s)
119
- 6 clusters with 3 procs (0.3s)
119
+ 6 clusters with 3 procs (0.2s)
120
120
  6 clusters with 2 procs (0.2s)
121
121
  3 clusters with 1 proc (0.2s)
122
- partition loop time: 1.5
122
+ partition loop time: 1.4
123
123
  getting annotations for final partition
124
- subcluster annotating 3 clusters with steps: (0.3s) (0.2s) (0.2s)
125
- subcluster annotation time 0.7
124
+ subcluster annotating 3 clusters with steps: (0.2s) (0.2s) (0.1s)
125
+ subcluster annotation time 0.6
126
126
  warning added 3 / 21 missing ids as singletons to inferred partition, to match ids in true partition
127
127
  warning added 3 / 21 missing ids as singletons to inferred partition, to match ids in true partition
128
128
  warning added 3 / 21 missing ids as singletons to inferred partition, to match ids in true partition
129
129
  warning added 3 / 21 missing ids as singletons to inferred partition, to match ids in true partition
130
130
  warning added 3 / 21 missing ids as singletons to inferred partition, to match ids in true partition
131
131
  warning added 3 / 21 missing ids as singletons to inferred partition, to match ids in true partition
132
- total time: 2.3
132
+ total time: 2.1
133
133
  combining chains
134
134
  cleaning pair info for 107 seqs
135
135
  synchronized/fixed 0 pairs where one had no pair info after cleaning: h 0 k 0 l 0
@@ -172,15 +172,15 @@ WARNING using errors instead of sumw2 with weight != 1.0 in Hist::fill_ibin()
172
172
  --input-partition-fname: read best partition with 35 sequences in 15 clusters from test/paired/new-results/subset-partition-new-simu/igh+igk/partition-igh-only-partition.yaml
173
173
  annotating (with test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igh/hmm)
174
174
  smith-waterman
175
- vsearch: 35 / 35 v annotations (0 failed) with 5 v genes in 0.1 sec
175
+ vsearch: 35 / 35 v annotations (0 failed) with 5 v genes in 0.2 sec
176
176
  reading sw results from test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igh/sw-cache.yaml
177
177
  info for 35 / 35 = 1.000 (removed: 0 failed, 0 duplicates [removed when cache file was written])
178
178
  kept 13 (0.371) unproductive
179
179
  water time: 0.0
180
180
  hmm
181
- subcluster annotating 15 clusters with steps: (0.5s) (0.3s)
182
- subcluster annotation time 0.8
183
- total time: 1.0
181
+ subcluster annotating 15 clusters with steps: (0.7s) (0.3s)
182
+ subcluster annotation time 0.9
183
+ total time: 1.2
184
184
  need to get annotations for 13/15 joint igk clusters
185
185
  annotate igh+igk: igk
186
186
  removed 1 arg strs that were specific to action 'partition': --continue-from-input-partition
@@ -189,15 +189,15 @@ hmm
189
189
  --input-partition-fname: read best partition with 36 sequences in 15 clusters from test/paired/new-results/subset-partition-new-simu/igh+igk/partition-igk-only-partition.yaml
190
190
  annotating (with test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igk/hmm)
191
191
  smith-waterman
192
- vsearch: 36 / 36 v annotations (0 failed) with 5 v genes in 0.1 sec
192
+ vsearch: 36 / 36 v annotations (0 failed) with 5 v genes in 0.2 sec
193
193
  reading sw results from test/paired/new-results/subset-partition-new-simu/merged-subsets/parameters/igk/sw-cache.yaml
194
194
  info for 36 / 36 = 1.000 (removed: 0 failed, 0 duplicates [removed when cache file was written])
195
195
  kept 14 (0.389) unproductive
196
196
  water time: 0.0
197
197
  hmm
198
- subcluster annotating 15 clusters with steps: (0.5s) (0.1s)
199
- subcluster annotation time 0.6
200
- total time: 0.8
198
+ subcluster annotating 15 clusters with steps: (0.6s) (0.2s)
199
+ subcluster annotation time 0.8
200
+ total time: 1.1
201
201
  igh+igl: synchronizing heavy and light chain cluster paths
202
202
  removing badly + unpaired seqs: kept 3 total unpaired (i.e. setting aside in order to reintegrate after paired clustering): h 2 l 1
203
203
  note: discarding unpaired seqs in families with no (well-)paired seqs (i.e. families that are all either unpaired or paired to the other/wrong light chain), rather than keeping track of them to re-add later
@@ -239,9 +239,9 @@ smith-waterman
239
239
  kept 11 (0.579) unproductive
240
240
  water time: 0.0
241
241
  hmm
242
- subcluster annotating 6 clusters with steps: (0.4s) (0.3s) (0.3s)
243
- subcluster annotation time 1.0
244
- total time: 1.1
242
+ subcluster annotating 6 clusters with steps: (0.6s) (0.3s) (0.5s)
243
+ subcluster annotation time 1.4
244
+ total time: 1.6
245
245
  need to get annotations for 6/6 joint igl clusters
246
246
  annotate igh+igl: igl
247
247
  removed 1 arg strs that were specific to action 'partition': --continue-from-input-partition
@@ -256,9 +256,9 @@ smith-waterman
256
256
  kept 13 (0.722) unproductive
257
257
  water time: 0.0
258
258
  hmm
259
- subcluster annotating 6 clusters with steps: (0.3s) (0.2s) (0.2s)
259
+ subcluster annotating 6 clusters with steps: (0.4s) (0.2s) (0.1s)
260
260
  subcluster annotation time 0.7
261
- total time: 0.9
261
+ total time: 0.8
262
262
  --input-metafnames: no meta info added from test/paired/new-results/subset-partition-new-simu/merged-subsets/meta.yaml
263
263
  concatenating heavy chain loci:
264
264
  h starting with 15 annotations (35 seqs)
@@ -272,4 +272,4 @@ hmm
272
272
  h 18 --> 21 +3
273
273
  k 6 --> 15 +9
274
274
  l 3 --> 6 +3
275
- total time: 26.9
275
+ total time: 34.7