geney 1.3.61__py2.py3-none-any.whl → 1.3.63__py2.py3-none-any.whl
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- geney/oncosplice.py +3 -0
- geney/utils.py +21 -0
- {geney-1.3.61.dist-info → geney-1.3.63.dist-info}/METADATA +1 -1
- {geney-1.3.61.dist-info → geney-1.3.63.dist-info}/RECORD +6 -6
- {geney-1.3.61.dist-info → geney-1.3.63.dist-info}/WHEEL +0 -0
- {geney-1.3.61.dist-info → geney-1.3.63.dist-info}/top_level.txt +0 -0
geney/oncosplice.py
CHANGED
|
@@ -370,6 +370,8 @@ def oncosplice(mut_id, splicing_threshold=0.5, protein_coding=True, cons_require
|
|
|
370
370
|
|
|
371
371
|
alternative_splicing_paths = develop_aberrant_splicing(reference_transcript, missplicing.missplicing)
|
|
372
372
|
for i, new_boundaries in enumerate(alternative_splicing_paths):
|
|
373
|
+
print("iterating through new boundaries...")
|
|
374
|
+
|
|
373
375
|
mutated_transcript.acceptors = new_boundaries['acceptors']
|
|
374
376
|
mutated_transcript.donors = new_boundaries['donors']
|
|
375
377
|
mutated_transcript.generate_mature_mrna().generate_protein()
|
|
@@ -413,6 +415,7 @@ def oncosplice(mut_id, splicing_threshold=0.5, protein_coding=True, cons_require
|
|
|
413
415
|
results.append(report)
|
|
414
416
|
|
|
415
417
|
if len(results) == 0:
|
|
418
|
+
print("Nothing...")
|
|
416
419
|
return None
|
|
417
420
|
|
|
418
421
|
return pd.DataFrame(results)[
|
geney/utils.py
CHANGED
|
@@ -78,3 +78,24 @@ def is_monotonic(A):
|
|
|
78
78
|
# return rev_compl
|
|
79
79
|
#
|
|
80
80
|
|
|
81
|
+
|
|
82
|
+
def generate_random_nucleotide_sequences(num_sequences, min_len=3, max_len=10):
|
|
83
|
+
"""
|
|
84
|
+
Generate random sequences of nucleotides.
|
|
85
|
+
|
|
86
|
+
Parameters:
|
|
87
|
+
num_sequences (int): Number of sequences to generate.
|
|
88
|
+
sequence_length (int): Length of each sequence.
|
|
89
|
+
|
|
90
|
+
Returns:
|
|
91
|
+
list: A list of random nucleotide sequences.
|
|
92
|
+
"""
|
|
93
|
+
import random
|
|
94
|
+
nucleotides = ['A', 'C', 'G', 'T']
|
|
95
|
+
lengths = list(range(min_len, max_len))
|
|
96
|
+
sequences = [
|
|
97
|
+
''.join(random.choices(nucleotides, k=random.choice(lengths)))
|
|
98
|
+
for _ in range(num_sequences)
|
|
99
|
+
]
|
|
100
|
+
return sequences
|
|
101
|
+
|
|
@@ -11,7 +11,7 @@ geney/graphic_utils.py,sha256=oMsBpB9YeEn96gGpKh4MmtagJffWZbk-xPrIwHvkFhA,11016
|
|
|
11
11
|
geney/gtex_utils.py,sha256=asL2lHyU5KsbWpV096vkf1Ka7hSo_RRfZqw7p5nERmE,1919
|
|
12
12
|
geney/immune_utils.py,sha256=ZRni5ttrhpYBnmNr0d0ZatIbNPYs4nmQuoUO00SpsS4,5271
|
|
13
13
|
geney/mutation_utils.py,sha256=C_kv2MB_L8LlhX3W2ooXjJ3uDoJ8zX1WeDtZKoBZJkI,1547
|
|
14
|
-
geney/oncosplice.py,sha256=
|
|
14
|
+
geney/oncosplice.py,sha256=5O8oXnh73SEdweuaCQs0gmIja0CDjEj8KNL0aXg5lQQ,24790
|
|
15
15
|
geney/pangolin_utils.py,sha256=9jdBXlOcRaUdfi-UpUxHA0AkTMZkUF-Lt7HVZ1nEm3s,2973
|
|
16
16
|
geney/power_utils.py,sha256=MehZFUdkJ2EFUot709yPEDxSkXmH5XevMebX2HD768A,7330
|
|
17
17
|
geney/seqmat_utils.py,sha256=wzb3PX5it5bpIFQvcxyzlxfhoJTbHHbsjg0rzh05iVs,19753
|
|
@@ -20,12 +20,12 @@ geney/splicing_utils.py,sha256=GDSuuy8kWBh2_4UDwqjclF9gKnnCoLc_neOEsSrNWQM,38512
|
|
|
20
20
|
geney/survival_utils.py,sha256=KnAzEviMuXh6SnVXId9PgsFLSbgkduTvYoIthxN7FPA,6886
|
|
21
21
|
geney/tcga_utils.py,sha256=D_BNHm-D_K408dlcJm3hzH2c6QNFjQsKvUcOPiQRk7g,17612
|
|
22
22
|
geney/tis_utils.py,sha256=la0CZroaKe5RgAyFd4Bf_DqQncklWgAY2823xVst98o,7813
|
|
23
|
-
geney/utils.py,sha256=
|
|
23
|
+
geney/utils.py,sha256=KBdwNIywo7INVEQEsuIXauEJobvReE9TXAi5qqXanSI,2775
|
|
24
24
|
geney/translation_initiation/__init__.py,sha256=47DEQpj8HBSa-_TImW-5JCeuQeRkm5NMpJWZG3hSuFU,0
|
|
25
25
|
geney/translation_initiation/tis_utils.py,sha256=AF3siFjuQH-Rs44EV-80zHdbxRMvN4woLFSHroWIETc,4448
|
|
26
26
|
geney/translation_initiation/resources/kozak_pssm.json,sha256=pcd0Olziutq-6H3mFWDCD9cujQ_AlZO-iiOvBl82hqE,1165
|
|
27
27
|
geney/translation_initiation/resources/tis_regressor_model.joblib,sha256=IXb4DUDhJ5rBDKcqMk9zE3ECTZZcdj7Jixz3KpoZ7OA,2592025
|
|
28
|
-
geney-1.3.
|
|
29
|
-
geney-1.3.
|
|
30
|
-
geney-1.3.
|
|
31
|
-
geney-1.3.
|
|
28
|
+
geney-1.3.63.dist-info/METADATA,sha256=lis1MZ3LovEMzTuqZthCmPxQ26p4XbeXxdhbtb4qgPo,990
|
|
29
|
+
geney-1.3.63.dist-info/WHEEL,sha256=AHX6tWk3qWuce7vKLrj7lnulVHEdWoltgauo8bgCXgU,109
|
|
30
|
+
geney-1.3.63.dist-info/top_level.txt,sha256=O-FuNUMb5fn9dhZ-dYCgF0aZtfi1EslMstnzhc5IIVo,6
|
|
31
|
+
geney-1.3.63.dist-info/RECORD,,
|
|
File without changes
|
|
File without changes
|