TSUMUGI 1.0.1__py3-none-any.whl
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- TSUMUGI/annotator.py +103 -0
- TSUMUGI/argparser.py +599 -0
- TSUMUGI/core.py +185 -0
- TSUMUGI/data/impc_phenodigm.csv +3406 -0
- TSUMUGI/data/mp.obo +143993 -0
- TSUMUGI/filterer.py +36 -0
- TSUMUGI/formatter.py +122 -0
- TSUMUGI/genewise_annotation_builder.py +94 -0
- TSUMUGI/io_handler.py +189 -0
- TSUMUGI/main.py +300 -0
- TSUMUGI/network_constructor.py +603 -0
- TSUMUGI/ontology_handler.py +62 -0
- TSUMUGI/pairwise_similarity_builder.py +66 -0
- TSUMUGI/report_generator.py +122 -0
- TSUMUGI/similarity_calculator.py +498 -0
- TSUMUGI/subcommands/count_filterer.py +47 -0
- TSUMUGI/subcommands/genes_filterer.py +89 -0
- TSUMUGI/subcommands/graphml_builder.py +158 -0
- TSUMUGI/subcommands/life_stage_filterer.py +48 -0
- TSUMUGI/subcommands/mp_filterer.py +142 -0
- TSUMUGI/subcommands/score_filterer.py +22 -0
- TSUMUGI/subcommands/sex_filterer.py +48 -0
- TSUMUGI/subcommands/webapp_builder.py +358 -0
- TSUMUGI/subcommands/zygosity_filterer.py +48 -0
- TSUMUGI/validator.py +65 -0
- TSUMUGI/web/app/css/app.css +1129 -0
- TSUMUGI/web/app/genelist/network_genelist.html +339 -0
- TSUMUGI/web/app/genelist/network_genelist.js +421 -0
- TSUMUGI/web/app/js/data/dataLoader.js +41 -0
- TSUMUGI/web/app/js/export/graphExporter.js +214 -0
- TSUMUGI/web/app/js/graph/centrality.js +495 -0
- TSUMUGI/web/app/js/graph/components.js +30 -0
- TSUMUGI/web/app/js/graph/filters.js +158 -0
- TSUMUGI/web/app/js/graph/highlighter.js +52 -0
- TSUMUGI/web/app/js/graph/layoutController.js +454 -0
- TSUMUGI/web/app/js/graph/valueScaler.js +43 -0
- TSUMUGI/web/app/js/search/geneSearcher.js +93 -0
- TSUMUGI/web/app/js/search/phenotypeSearcher.js +292 -0
- TSUMUGI/web/app/js/ui/dynamicFontSize.js +30 -0
- TSUMUGI/web/app/js/ui/mobilePanel.js +77 -0
- TSUMUGI/web/app/js/ui/slider.js +22 -0
- TSUMUGI/web/app/js/ui/tooltips.js +514 -0
- TSUMUGI/web/app/js/viewer/pageSetup.js +217 -0
- TSUMUGI/web/app/viewer.html +515 -0
- TSUMUGI/web/app/viewer.js +1593 -0
- TSUMUGI/web/css/sanitize.css +363 -0
- TSUMUGI/web/css/top.css +391 -0
- TSUMUGI/web/image/tsumugi-favicon.ico +0 -0
- TSUMUGI/web/image/tsumugi-icon.png +0 -0
- TSUMUGI/web/image/tsumugi-logo.png +0 -0
- TSUMUGI/web/image/tsumugi-logo.svg +69 -0
- TSUMUGI/web/js/genelist_formatter.js +123 -0
- TSUMUGI/web/js/top.js +338 -0
- TSUMUGI/web/open_webapp_linux.sh +25 -0
- TSUMUGI/web/open_webapp_mac.command +25 -0
- TSUMUGI/web/open_webapp_windows.bat +37 -0
- TSUMUGI/web/serve_index.py +110 -0
- TSUMUGI/web/template/template_index.html +197 -0
- TSUMUGI/web_deployer.py +150 -0
- tsumugi-1.0.1.dist-info/METADATA +504 -0
- tsumugi-1.0.1.dist-info/RECORD +64 -0
- tsumugi-1.0.1.dist-info/WHEEL +4 -0
- tsumugi-1.0.1.dist-info/entry_points.txt +3 -0
- tsumugi-1.0.1.dist-info/licenses/LICENSE +21 -0
TSUMUGI/web/css/top.css
ADDED
|
@@ -0,0 +1,391 @@
|
|
|
1
|
+
/* ======================================================== */
|
|
2
|
+
/* General body styling */
|
|
3
|
+
/* ======================================================== */
|
|
4
|
+
body {
|
|
5
|
+
color: #333;
|
|
6
|
+
background-color: #FFEBD8;
|
|
7
|
+
font-family: 'Lato', 'Arial', 'Helvetica', sans-serif;
|
|
8
|
+
font-size: 1.2em;
|
|
9
|
+
min-height: 100vh;
|
|
10
|
+
margin: 0 auto;
|
|
11
|
+
padding-top: 50px;
|
|
12
|
+
display: flex;
|
|
13
|
+
justify-content: flex-start;
|
|
14
|
+
text-align: center;
|
|
15
|
+
align-items: center;
|
|
16
|
+
flex-direction: column;
|
|
17
|
+
}
|
|
18
|
+
|
|
19
|
+
h1 {
|
|
20
|
+
margin: 0 auto;
|
|
21
|
+
}
|
|
22
|
+
|
|
23
|
+
/* Inherit font settings for form elements */
|
|
24
|
+
button,
|
|
25
|
+
input,
|
|
26
|
+
textarea,
|
|
27
|
+
select {
|
|
28
|
+
color: inherit;
|
|
29
|
+
font-size: inherit;
|
|
30
|
+
font-family: inherit;
|
|
31
|
+
}
|
|
32
|
+
|
|
33
|
+
/* Subtitle styling */
|
|
34
|
+
p.subtitle {
|
|
35
|
+
font-family: 'Lora', serif;
|
|
36
|
+
margin-bottom: 20px;
|
|
37
|
+
}
|
|
38
|
+
|
|
39
|
+
/* ======================================================== */
|
|
40
|
+
/* Form container styling */
|
|
41
|
+
/* ======================================================== */
|
|
42
|
+
form {
|
|
43
|
+
background-color: #fefefe;
|
|
44
|
+
padding: 30px;
|
|
45
|
+
border-radius: 10px;
|
|
46
|
+
max-width: 600px;
|
|
47
|
+
width: 100%;
|
|
48
|
+
margin: 20px 0 40px;
|
|
49
|
+
}
|
|
50
|
+
|
|
51
|
+
/* Image styling */
|
|
52
|
+
img {
|
|
53
|
+
width: 80%;
|
|
54
|
+
height: auto;
|
|
55
|
+
}
|
|
56
|
+
|
|
57
|
+
/* Label styling */
|
|
58
|
+
label {
|
|
59
|
+
margin-bottom: 10px;
|
|
60
|
+
display: block;
|
|
61
|
+
}
|
|
62
|
+
|
|
63
|
+
/* Text input field styling */
|
|
64
|
+
input[type="text"] {
|
|
65
|
+
width: 80%;
|
|
66
|
+
padding: 10px;
|
|
67
|
+
border: 2px solid #ccc;
|
|
68
|
+
border-radius: 10px;
|
|
69
|
+
margin-bottom: 10px;
|
|
70
|
+
box-sizing: border-box;
|
|
71
|
+
outline: none;
|
|
72
|
+
}
|
|
73
|
+
|
|
74
|
+
input[type="text"]:focus {
|
|
75
|
+
border-color: #ccc;
|
|
76
|
+
outline: none;
|
|
77
|
+
}
|
|
78
|
+
|
|
79
|
+
/* -------------------------------------------------------- */
|
|
80
|
+
/* Suggestions list styling */
|
|
81
|
+
/* -------------------------------------------------------- */
|
|
82
|
+
|
|
83
|
+
ul.suggestions {
|
|
84
|
+
list-style: none;
|
|
85
|
+
padding: 0;
|
|
86
|
+
border: 1px solid #ccc;
|
|
87
|
+
border-radius: 10px;
|
|
88
|
+
max-height: 30vh;
|
|
89
|
+
overflow-y: auto;
|
|
90
|
+
}
|
|
91
|
+
|
|
92
|
+
ul.suggestions li {
|
|
93
|
+
padding: 10px;
|
|
94
|
+
cursor: pointer;
|
|
95
|
+
background-color: #fff;
|
|
96
|
+
transition: background-color 0.3s ease;
|
|
97
|
+
}
|
|
98
|
+
|
|
99
|
+
ul.suggestions li:hover {
|
|
100
|
+
background-color: #FFEBD8;
|
|
101
|
+
}
|
|
102
|
+
|
|
103
|
+
/* -------------------------------------------------------- */
|
|
104
|
+
/* Tab styling */
|
|
105
|
+
/* -------------------------------------------------------- */
|
|
106
|
+
|
|
107
|
+
.Tab-container {
|
|
108
|
+
display: flex;
|
|
109
|
+
flex-wrap: nowrap;
|
|
110
|
+
justify-content: center;
|
|
111
|
+
gap: 5px;
|
|
112
|
+
flex-direction: row;
|
|
113
|
+
}
|
|
114
|
+
|
|
115
|
+
button.Tab {
|
|
116
|
+
flex: 0 1 auto;
|
|
117
|
+
padding: 10px 20px;
|
|
118
|
+
margin: 0 5px;
|
|
119
|
+
border: 2px solid #ff7800;
|
|
120
|
+
border-radius: 10px;
|
|
121
|
+
background-color: #fff;
|
|
122
|
+
cursor: pointer;
|
|
123
|
+
transition: background-color 0.3s ease, color 0.3s ease;
|
|
124
|
+
position: relative;
|
|
125
|
+
z-index: 1;
|
|
126
|
+
|
|
127
|
+
display: flex;
|
|
128
|
+
align-items: center;
|
|
129
|
+
justify-content: center;
|
|
130
|
+
text-align: center;
|
|
131
|
+
}
|
|
132
|
+
|
|
133
|
+
button.Tab:hover {
|
|
134
|
+
background-color: #ffe2c2;
|
|
135
|
+
}
|
|
136
|
+
|
|
137
|
+
button.Tab.active-tab {
|
|
138
|
+
background-color: #ff7800;
|
|
139
|
+
color: #fff;
|
|
140
|
+
}
|
|
141
|
+
|
|
142
|
+
button.Tab.active-tab::after {
|
|
143
|
+
content: '';
|
|
144
|
+
width: 0;
|
|
145
|
+
height: 0;
|
|
146
|
+
border-style: solid;
|
|
147
|
+
border-width: 10px 10px 0 10px;
|
|
148
|
+
border-color: #ff7800 transparent transparent transparent;
|
|
149
|
+
position: absolute;
|
|
150
|
+
bottom: -10px;
|
|
151
|
+
left: 50%;
|
|
152
|
+
margin-left: -10px;
|
|
153
|
+
}
|
|
154
|
+
|
|
155
|
+
/* -------------------------------------------------------- */
|
|
156
|
+
/* Input form of gene lists */
|
|
157
|
+
/* -------------------------------------------------------- */
|
|
158
|
+
textarea.geneList {
|
|
159
|
+
max-width: 1200px;
|
|
160
|
+
height: 120px;
|
|
161
|
+
padding: 12px;
|
|
162
|
+
border: 2px solid #ccc;
|
|
163
|
+
border-radius: 10px;
|
|
164
|
+
resize: both;
|
|
165
|
+
}
|
|
166
|
+
|
|
167
|
+
textarea.geneList:focus {
|
|
168
|
+
border-color: #ccc;
|
|
169
|
+
outline: none;
|
|
170
|
+
}
|
|
171
|
+
|
|
172
|
+
/* -------------------------------------------------------- */
|
|
173
|
+
/* Submit button styling */
|
|
174
|
+
/* -------------------------------------------------------- */
|
|
175
|
+
button.submitBtn {
|
|
176
|
+
padding: 12px 20px;
|
|
177
|
+
color: #fff;
|
|
178
|
+
background-color: #ff7800;
|
|
179
|
+
border: none;
|
|
180
|
+
border-radius: 10px;
|
|
181
|
+
cursor: pointer;
|
|
182
|
+
transition: background-color 0.3s ease;
|
|
183
|
+
}
|
|
184
|
+
|
|
185
|
+
button.submitBtn:disabled {
|
|
186
|
+
background-color: #999;
|
|
187
|
+
cursor: not-allowed;
|
|
188
|
+
}
|
|
189
|
+
|
|
190
|
+
button.submitBtn:hover:enabled {
|
|
191
|
+
background-color: #e66900;
|
|
192
|
+
}
|
|
193
|
+
|
|
194
|
+
|
|
195
|
+
/* ======================================================== */
|
|
196
|
+
/* Resources Section */
|
|
197
|
+
/* ======================================================== */
|
|
198
|
+
|
|
199
|
+
.resources-container {
|
|
200
|
+
max-width: 800px;
|
|
201
|
+
margin: 0 auto 40px;
|
|
202
|
+
display: flex;
|
|
203
|
+
flex-wrap: wrap;
|
|
204
|
+
gap: 30px;
|
|
205
|
+
justify-content: center;
|
|
206
|
+
}
|
|
207
|
+
|
|
208
|
+
.resource-section {
|
|
209
|
+
flex: 1;
|
|
210
|
+
min-width: 280px;
|
|
211
|
+
text-align: center;
|
|
212
|
+
}
|
|
213
|
+
|
|
214
|
+
.resource-section h3 {
|
|
215
|
+
margin-bottom: 15px;
|
|
216
|
+
font-size: 1.1em;
|
|
217
|
+
color: #555;
|
|
218
|
+
font-weight: normal;
|
|
219
|
+
}
|
|
220
|
+
|
|
221
|
+
.resource-buttons {
|
|
222
|
+
display: flex;
|
|
223
|
+
flex-direction: column;
|
|
224
|
+
gap: 10px;
|
|
225
|
+
}
|
|
226
|
+
|
|
227
|
+
.resource-btn {
|
|
228
|
+
display: inline-flex;
|
|
229
|
+
align-items: center;
|
|
230
|
+
justify-content: center;
|
|
231
|
+
background-color: #fff;
|
|
232
|
+
color: #555;
|
|
233
|
+
padding: 10px 16px;
|
|
234
|
+
border: 2px solid #ccc;
|
|
235
|
+
border-radius: 10px;
|
|
236
|
+
text-decoration: none;
|
|
237
|
+
font-size: 0.95em;
|
|
238
|
+
transition: all 0.2s ease;
|
|
239
|
+
}
|
|
240
|
+
|
|
241
|
+
.resource-btn:hover {
|
|
242
|
+
color: #333;
|
|
243
|
+
border-color: #ff7800;
|
|
244
|
+
background-color: rgba(255, 120, 0, 0.05);
|
|
245
|
+
}
|
|
246
|
+
|
|
247
|
+
.resource-btn i {
|
|
248
|
+
margin-right: 6px;
|
|
249
|
+
font-size: 0.9em;
|
|
250
|
+
}
|
|
251
|
+
|
|
252
|
+
/* ======================================================== */
|
|
253
|
+
/* Info Tooltip Styles */
|
|
254
|
+
/* ======================================================== */
|
|
255
|
+
.info-tooltip-container {
|
|
256
|
+
position: relative;
|
|
257
|
+
display: inline-block;
|
|
258
|
+
margin-left: 8px;
|
|
259
|
+
}
|
|
260
|
+
|
|
261
|
+
.info-tooltip-icon {
|
|
262
|
+
display: inline-flex;
|
|
263
|
+
align-items: center;
|
|
264
|
+
justify-content: center;
|
|
265
|
+
width: 16px;
|
|
266
|
+
height: 16px;
|
|
267
|
+
border-radius: 50%;
|
|
268
|
+
background-color: #555;
|
|
269
|
+
color: white;
|
|
270
|
+
font-size: 12px;
|
|
271
|
+
font-weight: bold;
|
|
272
|
+
cursor: pointer;
|
|
273
|
+
transition: background-color 0.2s ease;
|
|
274
|
+
}
|
|
275
|
+
|
|
276
|
+
.info-tooltip-icon:hover {
|
|
277
|
+
background-color: #333;
|
|
278
|
+
}
|
|
279
|
+
|
|
280
|
+
.info-tooltip-content {
|
|
281
|
+
visibility: hidden;
|
|
282
|
+
opacity: 0;
|
|
283
|
+
position: absolute;
|
|
284
|
+
bottom: 25px;
|
|
285
|
+
left: 50%;
|
|
286
|
+
transform: translateX(-50%);
|
|
287
|
+
background-color: #333;
|
|
288
|
+
color: white;
|
|
289
|
+
text-align: left;
|
|
290
|
+
padding: 8px 12px;
|
|
291
|
+
border-radius: 6px;
|
|
292
|
+
font-size: 14px;
|
|
293
|
+
font-weight: normal;
|
|
294
|
+
line-height: 1.4;
|
|
295
|
+
white-space: nowrap;
|
|
296
|
+
z-index: 1000;
|
|
297
|
+
transition: opacity 0.3s ease, visibility 0.3s ease;
|
|
298
|
+
box-shadow: 0 2px 10px rgba(0,0,0,0.2);
|
|
299
|
+
max-width: 300px;
|
|
300
|
+
white-space: normal;
|
|
301
|
+
}
|
|
302
|
+
|
|
303
|
+
.info-tooltip-content::after {
|
|
304
|
+
content: "";
|
|
305
|
+
position: absolute;
|
|
306
|
+
top: 100%;
|
|
307
|
+
left: 50%;
|
|
308
|
+
transform: translateX(-50%);
|
|
309
|
+
border: 5px solid transparent;
|
|
310
|
+
border-top-color: #333;
|
|
311
|
+
}
|
|
312
|
+
|
|
313
|
+
.info-tooltip-container:hover .info-tooltip-content,
|
|
314
|
+
.info-tooltip-container.active .info-tooltip-content {
|
|
315
|
+
visibility: visible;
|
|
316
|
+
opacity: 1;
|
|
317
|
+
}
|
|
318
|
+
|
|
319
|
+
.info-tooltip-content a {
|
|
320
|
+
color: #4fc3f7;
|
|
321
|
+
text-decoration: underline;
|
|
322
|
+
}
|
|
323
|
+
|
|
324
|
+
.info-tooltip-content a:hover {
|
|
325
|
+
color: #81d4fa;
|
|
326
|
+
}
|
|
327
|
+
|
|
328
|
+
/* ======================================================== */
|
|
329
|
+
/* Footer styling */
|
|
330
|
+
/* ======================================================== */
|
|
331
|
+
|
|
332
|
+
footer {
|
|
333
|
+
margin: 20px 0 10px;
|
|
334
|
+
padding: 20px;
|
|
335
|
+
width: 100%;
|
|
336
|
+
color: #666;
|
|
337
|
+
font-size: 0.9em;
|
|
338
|
+
}
|
|
339
|
+
|
|
340
|
+
footer p {
|
|
341
|
+
margin: 5px 0 0;
|
|
342
|
+
}
|
|
343
|
+
|
|
344
|
+
footer i {
|
|
345
|
+
margin-right: 8px;
|
|
346
|
+
}
|
|
347
|
+
|
|
348
|
+
footer a {
|
|
349
|
+
color: #666;
|
|
350
|
+
font-size: 1em;
|
|
351
|
+
text-decoration: none;
|
|
352
|
+
font-weight: bold;
|
|
353
|
+
}
|
|
354
|
+
|
|
355
|
+
footer a:hover {
|
|
356
|
+
text-decoration: underline;
|
|
357
|
+
}
|
|
358
|
+
|
|
359
|
+
|
|
360
|
+
|
|
361
|
+
/* ======================================================== */
|
|
362
|
+
/* Responsive design for mobile devices */
|
|
363
|
+
/* ======================================================== */
|
|
364
|
+
@media screen and (max-width: 600px) {
|
|
365
|
+
body {
|
|
366
|
+
font-size: 1em;
|
|
367
|
+
padding-top: 20px;
|
|
368
|
+
}
|
|
369
|
+
|
|
370
|
+
form {
|
|
371
|
+
width: 90%;
|
|
372
|
+
}
|
|
373
|
+
|
|
374
|
+
button.Tab {
|
|
375
|
+
padding: 8px 10px;
|
|
376
|
+
font-size: 0.9em;
|
|
377
|
+
margin: 2px;
|
|
378
|
+
min-width: 30px;
|
|
379
|
+
white-space: nowrap;
|
|
380
|
+
}
|
|
381
|
+
|
|
382
|
+
.resources-container {
|
|
383
|
+
flex-direction: column;
|
|
384
|
+
gap: 20px;
|
|
385
|
+
margin-bottom: 30px;
|
|
386
|
+
}
|
|
387
|
+
|
|
388
|
+
.resource-section {
|
|
389
|
+
min-width: auto;
|
|
390
|
+
}
|
|
391
|
+
}
|
|
Binary file
|
|
Binary file
|
|
Binary file
|
|
@@ -0,0 +1,69 @@
|
|
|
1
|
+
<?xml version="1.0" encoding="UTF-8" standalone="no"?>
|
|
2
|
+
<svg
|
|
3
|
+
width="211.125pt"
|
|
4
|
+
height="89.0625pt"
|
|
5
|
+
viewBox="0 0 211.125 89.0625"
|
|
6
|
+
version="1.1"
|
|
7
|
+
id="svg9"
|
|
8
|
+
xml:space="preserve"
|
|
9
|
+
xmlns="http://www.w3.org/2000/svg"
|
|
10
|
+
xmlns:svg="http://www.w3.org/2000/svg"
|
|
11
|
+
xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
|
|
12
|
+
xmlns:cc="http://creativecommons.org/ns#"
|
|
13
|
+
xmlns:dc="http://purl.org/dc/elements/1.1/"><metadata
|
|
14
|
+
id="metadata1"><rdf:RDF><cc:Work><dc:type
|
|
15
|
+
rdf:resource="http://purl.org/dc/dcmitype/StillImage" /><dc:date>2024-09-02T05:33:13.416149</dc:date><dc:format>image/svg+xml</dc:format><dc:creator><cc:Agent><dc:title>Matplotlib v3.6.3, https://matplotlib.org/</dc:title></cc:Agent></dc:creator></cc:Work></rdf:RDF></metadata><defs
|
|
16
|
+
id="defs1"><style
|
|
17
|
+
type="text/css"
|
|
18
|
+
id="style1">*{stroke-linejoin: round; stroke-linecap: butt}</style></defs><text
|
|
19
|
+
xml:space="preserve"
|
|
20
|
+
style="font-style:normal;font-variant:normal;font-weight:normal;font-stretch:normal;font-size:50px;line-height:1;font-family:Rubik;-inkscape-font-specification:Rubik;text-align:center;text-decoration-color:#000000;letter-spacing:0px;word-spacing:0px;fill:#241f31;stroke:none;stroke-width:1;stroke-dasharray:none;paint-order:stroke fill markers"
|
|
21
|
+
x="9.4352112"
|
|
22
|
+
y="38.838974"
|
|
23
|
+
id="text9"><tspan
|
|
24
|
+
id="tspan9"
|
|
25
|
+
style="font-style:normal;font-variant:normal;font-weight:normal;font-stretch:normal;font-size:50px;font-family:Sitka;-inkscape-font-specification:Sitka;fill:#241f31;stroke:#241f31;stroke-width:1;stroke-dasharray:none"
|
|
26
|
+
x="9.4352112"
|
|
27
|
+
y="38.838974">TSUMUGI</tspan></text><defs
|
|
28
|
+
id="defs9" /><g
|
|
29
|
+
id="g36"
|
|
30
|
+
transform="translate(-513.71215,-178.53485)"><path
|
|
31
|
+
style="fill:none;stroke:#9a9996;stroke-width:2;stroke-linecap:round;stroke-linejoin:bevel;stroke-dasharray:none;paint-order:stroke fill markers"
|
|
32
|
+
d="m 554.80558,244.25989 c 0,0 -3.11994,-9.82714 9.57484,-14.20237 8.68817,-2.81702 26.68892,6.90156 21.03104,14.87692 -2.04715,6.88644 14.82807,12.80336 18.94991,11.23936 11.80553,-4.47952 -2.22922,-18.21465 5.05772,-25.7882 2.41151,-2.50636 10.10116,-4.69468 19.69798,-1.6373 15.0872,4.80653 4.03664,16.85815 6.35645,23.20184 3.04075,4.5015 1.98067,9.04247 13.54931,8.30912 9.65289,-1.68304 9.27859,-8.0446 8.44725,-12.22987 -1.15959,-5.83777 -6.53765,-15.52976 2.87892,-17.84795 4.57253,-1.22483 11.06863,-1.20626 14.54124,7.71923 1.39314,3.58072 8.78514,4.46414 12.84501,4.87374"
|
|
33
|
+
id="path31-4" /><circle
|
|
34
|
+
style="fill:#ff7800;stroke:none;stroke-width:2;stroke-linecap:butt;stroke-linejoin:round;paint-order:stroke fill markers"
|
|
35
|
+
id="circle31-5"
|
|
36
|
+
cx="555.45587"
|
|
37
|
+
cy="244.82098"
|
|
38
|
+
r="6.4558659" /><circle
|
|
39
|
+
style="fill:#ff7800;stroke:none;stroke-width:2;stroke-linecap:butt;stroke-linejoin:round;paint-order:stroke fill markers"
|
|
40
|
+
id="circle32-8"
|
|
41
|
+
cx="585.62347"
|
|
42
|
+
cy="245.68243"
|
|
43
|
+
r="6.4558659" /><circle
|
|
44
|
+
style="fill:#ff7800;stroke:none;stroke-width:2;stroke-linecap:butt;stroke-linejoin:round;paint-order:stroke fill markers"
|
|
45
|
+
id="circle33-6"
|
|
46
|
+
cx="610.17987"
|
|
47
|
+
cy="230.70587"
|
|
48
|
+
r="6.4558659" /><circle
|
|
49
|
+
style="fill:#ff7800;stroke:none;stroke-width:2;stroke-linecap:butt;stroke-linejoin:round;paint-order:stroke fill markers"
|
|
50
|
+
id="circle34-3"
|
|
51
|
+
cx="636.00336"
|
|
52
|
+
cy="251.17627"
|
|
53
|
+
r="6.4558659" /><circle
|
|
54
|
+
style="fill:#ff7800;stroke:none;stroke-width:2;stroke-linecap:butt;stroke-linejoin:round;paint-order:stroke fill markers"
|
|
55
|
+
id="circle35-8"
|
|
56
|
+
cx="657.3017"
|
|
57
|
+
cy="248.20645"
|
|
58
|
+
r="6.4558659" /><circle
|
|
59
|
+
style="fill:#ff7800;stroke:none;stroke-width:2;stroke-linecap:butt;stroke-linejoin:round;paint-order:stroke fill markers"
|
|
60
|
+
id="circle36-8"
|
|
61
|
+
cx="688.01227"
|
|
62
|
+
cy="242.42432"
|
|
63
|
+
r="6.4558659" /></g><rect
|
|
64
|
+
style="fill:none;stroke:none;stroke-width:0.999997;stroke-linecap:round;stroke-linejoin:bevel;stroke-dasharray:none;paint-order:stroke fill markers"
|
|
65
|
+
id="rect36"
|
|
66
|
+
width="211.125"
|
|
67
|
+
height="89.0625"
|
|
68
|
+
x="-1.1368684e-13"
|
|
69
|
+
y="-2.8421709e-14" /></svg>
|
|
@@ -0,0 +1,123 @@
|
|
|
1
|
+
export async function fetchGzippedJson(url) {
|
|
2
|
+
try {
|
|
3
|
+
const response = await fetch(url);
|
|
4
|
+
if (!response.ok) {
|
|
5
|
+
throw new Error(`HTTP error: ${response.status}`);
|
|
6
|
+
}
|
|
7
|
+
const compressedData = await response.arrayBuffer();
|
|
8
|
+
const decompressedData = pako.inflate(compressedData, { to: "string" });
|
|
9
|
+
return JSON.parse(decompressedData);
|
|
10
|
+
} catch (error) {
|
|
11
|
+
console.error(`Data fetch error (${url}):`, error);
|
|
12
|
+
return null; // Skip on error
|
|
13
|
+
}
|
|
14
|
+
}
|
|
15
|
+
|
|
16
|
+
export function filterJson(jsonDataList, geneKeys) {
|
|
17
|
+
const elementsMap = new Map();
|
|
18
|
+
|
|
19
|
+
const serializePhenotypes = (phenotype) => {
|
|
20
|
+
if (Array.isArray(phenotype)) {
|
|
21
|
+
return JSON.stringify([...phenotype].sort());
|
|
22
|
+
}
|
|
23
|
+
if (typeof phenotype === "string") {
|
|
24
|
+
return JSON.stringify([phenotype]);
|
|
25
|
+
}
|
|
26
|
+
return JSON.stringify([]);
|
|
27
|
+
};
|
|
28
|
+
|
|
29
|
+
const buildEdgeKey = (data) => {
|
|
30
|
+
if (!("source" in data) || !("target" in data)) return null;
|
|
31
|
+
const pairKey = [data.source, data.target].sort().join("||");
|
|
32
|
+
return `edge:${pairKey}|${serializePhenotypes(data.phenotype)}`;
|
|
33
|
+
};
|
|
34
|
+
|
|
35
|
+
const buildNodeKey = (data) => ("id" in data ? `node:${data.id}` : null);
|
|
36
|
+
|
|
37
|
+
const upsertEdge = (key, item) => {
|
|
38
|
+
const existing = elementsMap.get(key);
|
|
39
|
+
const newEdgeSize = Number.isFinite(item.data.edge_size) ? item.data.edge_size : Number.NEGATIVE_INFINITY;
|
|
40
|
+
if (!existing) {
|
|
41
|
+
elementsMap.set(key, item);
|
|
42
|
+
return;
|
|
43
|
+
}
|
|
44
|
+
const existingEdgeSize = Number.isFinite(existing.data.edge_size)
|
|
45
|
+
? existing.data.edge_size
|
|
46
|
+
: Number.NEGATIVE_INFINITY;
|
|
47
|
+
if (newEdgeSize > existingEdgeSize) {
|
|
48
|
+
elementsMap.set(key, item);
|
|
49
|
+
}
|
|
50
|
+
};
|
|
51
|
+
|
|
52
|
+
jsonDataList.forEach((jsonData) => {
|
|
53
|
+
jsonData.forEach((item) => {
|
|
54
|
+
const data = item.data;
|
|
55
|
+
|
|
56
|
+
if ("node_color" in data && data.node_color !== 1) return;
|
|
57
|
+
|
|
58
|
+
const isEdge = "source" in data && "target" in data;
|
|
59
|
+
|
|
60
|
+
if (isEdge) {
|
|
61
|
+
if (!geneKeys.includes(data.source) || !geneKeys.includes(data.target)) return;
|
|
62
|
+
const edgeKey = buildEdgeKey(data);
|
|
63
|
+
if (!edgeKey) return;
|
|
64
|
+
upsertEdge(edgeKey, item);
|
|
65
|
+
return;
|
|
66
|
+
}
|
|
67
|
+
|
|
68
|
+
if ("id" in data && !geneKeys.includes(data.id)) return;
|
|
69
|
+
|
|
70
|
+
const nodeKey = buildNodeKey(data);
|
|
71
|
+
if (!nodeKey) return;
|
|
72
|
+
if (!elementsMap.has(nodeKey)) {
|
|
73
|
+
elementsMap.set(nodeKey, item);
|
|
74
|
+
}
|
|
75
|
+
});
|
|
76
|
+
});
|
|
77
|
+
|
|
78
|
+
return Array.from(elementsMap.values());
|
|
79
|
+
}
|
|
80
|
+
|
|
81
|
+
export async function fetchGeneData() {
|
|
82
|
+
let jsonDataList = [];
|
|
83
|
+
|
|
84
|
+
const geneList = document.getElementById("geneList").value;
|
|
85
|
+
const geneKeys = geneList
|
|
86
|
+
.split(/\r?\n/)
|
|
87
|
+
.map((gene) => gene.trim())
|
|
88
|
+
.filter((gene) => gene !== "");
|
|
89
|
+
|
|
90
|
+
const fetchPromises = geneKeys.map((gene) => fetchGzippedJson(`./data/genesymbol/${gene}.json.gz`));
|
|
91
|
+
|
|
92
|
+
const results = await Promise.all(fetchPromises);
|
|
93
|
+
jsonDataList = results.filter((data) => data !== null);
|
|
94
|
+
|
|
95
|
+
const elements = filterJson(jsonDataList, geneKeys);
|
|
96
|
+
|
|
97
|
+
const uniqueIds = new Set(elements.map((el) => el.data.id).filter((id) => id !== undefined));
|
|
98
|
+
|
|
99
|
+
if (uniqueIds.size === 0) {
|
|
100
|
+
alert("No similar phenotypes were found among the entered genes.");
|
|
101
|
+
return;
|
|
102
|
+
} else if (uniqueIds.size >= 200) {
|
|
103
|
+
alert("Too many genes submitted. Please limit the number to 200 or fewer.");
|
|
104
|
+
return;
|
|
105
|
+
}
|
|
106
|
+
|
|
107
|
+
localStorage.removeItem("elements");
|
|
108
|
+
localStorage.setItem("elements", JSON.stringify(elements));
|
|
109
|
+
const query = new URLSearchParams({
|
|
110
|
+
mode: "genelist",
|
|
111
|
+
name: "geneList",
|
|
112
|
+
title: "Gene List",
|
|
113
|
+
});
|
|
114
|
+
window.open(`./app/viewer.html?${query.toString()}`, "_blank");
|
|
115
|
+
}
|
|
116
|
+
|
|
117
|
+
// Expose for form submission handler
|
|
118
|
+
window.fetchGeneData = fetchGeneData;
|
|
119
|
+
|
|
120
|
+
// Assign event listener to button
|
|
121
|
+
document.addEventListener("DOMContentLoaded", () => {
|
|
122
|
+
document.getElementById("submitBtn_List").addEventListener("click", fetchGeneData);
|
|
123
|
+
});
|