npm - wuepgg3-track - Versions diffs - 2.0.0 → 2.0.1 - Mend

wuepgg3-track 2.0.0 → 2.0.1

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.

Files changed (15) hide show

package/dist/assets/fetchGenomeAlignWorker-Cxh6HnBI.js DELETED Viewed

@@ -1,59 +0,0 @@
-var CA=Object.defineProperty;var AA=(Qr,ar,Ii)=>ar in Qr?CA(Qr,ar,{enumerable:!0,configurable:!0,writable:!0,value:Ii}):Qr[ar]=Ii;var ue=(Qr,ar,Ii)=>AA(Qr,typeof ar!="symbol"?ar+"":ar,Ii);(function(){"use strict";var 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qn{constructor(e,t,a="",o=null){ue(this,"name");ue(this,"score");ue(this,"id");ue(this,"sequence");ue(this,"variant");ue(this,"value");this.locus=t,this.strand=a,this.name=e===void 0?t.toString():e,this.locus=t,this.strand=a,this.value=o}serialize(){return{name:this.name,locus:this.getLocus().serialize(),strand:this.strand}}static deserialize(e){return new qn(e.name,rt.deserialize(e.locus),e.strand)}getName(){return this.name}getLocus(){return this.locus}getLength(){return this.locus.getLength()}getStrand(){return this.strand}getIsForwardStrand(){return this.strand===Ig}getIsReverseStrand(){return this.strand===Tg}getHasStrand(){return this.getIsForwardStrand()||this.getIsReverseStrand()}computeNavContextCoordinates(e){return e.convertGenomeIntervalToBases(this.getLocus())}}const kg="-";class Rg extends qn{constructor(t){const a=new rt(t.chr,t.start,t.end);super(t[3].id,a,t.strand);ue(this,"queryLocus");ue(this,"targetSeq");ue(this,"querySeq");ue(this,"queryStrand");const{chr:o,start:s,stop:f,strand:h,targetseq:_,queryseq:d}=t[3].genomealign;this.queryLocus=new rt(o,s,f),this.querySeq=d||"",this.targetSeq=_||"",this.queryStrand=h}getIsReverseStrandQuery(){return this.queryStrand===kg}}class an{constructor(e,t=0,a){ue(this,"relativeStart");ue(this,"relativeEnd");if(this.feature=e,a===void 0&&(a=e.locus.end-e.locus.start),a<t)throw new RangeError("End cannot be less than start");this.feature=e,this.relativeStart=t,this.relativeEnd=a}get start(){return console.error("FeatureSegment has no prop `start`.  Use `relativeStart` instead."),this.relativeStart}get end(){return console.error("FeatureSegment has no prop `end`.  Use `relativeEnd` instead."),this.relativeEnd}toOpenInterval(){return new Ne(this.relativeStart,this.relativeEnd)}getName(){return this.feature.getName()}getLength(){return this.relativeEnd-this.relativeStart}getLocus(){const e=this.feature.locus;return new rt(e.chr,e.start+this.relativeStart,e.start+this.relativeEnd)}getOverlap(e){if(this.feature!==e.feature)return null;const t=this.toOpenInterval().getOverlap(e.toOpenInterval());return t?new an(this.feature,t.start,t.end):null}getGenomeOverlap(e){const t=this.feature.getLocus(),o=this.getLocus().getOverlap(e);if(!o)return null;const s=o.start-t.start,f=o.end-t.start;return new an(this.feature,s,f)}toString(){return`${this.getName()}:${this.relativeStart+1}-${this.relativeEnd}`}toStringWithOther(e){return`${this.getName()}:${this.relativeStart+1}-${e.getName()}:${e.relativeEnd}`}}const Xl="";class In{constructor(e,t){ue(this,"_name");ue(this,"_features");ue(this,"_sortedFeatureStarts");ue(this,"_minCoordinateForFeature");ue(this,"_featuresForChr");ue(this,"_totalBases");this._name=e,this._features=t,this._minCoordinateForFeature=new Map,this._sortedFeatureStarts=[],this._featuresForChr=Xt.groupBy(t,a=>a.getLocus().chr),this._totalBases=0;for(const a of t){if(this._minCoordinateForFeature.has(a))throw new Error(`Duplicate feature "${a.getName()}" detected.  Features must be unique.`);this._minCoordinateForFeature.set(a,this._totalBases),this._sortedFeatureStarts.push(this._totalBases),this._totalBases+=a.getLength()}}static makeGap(e,t="Gap"){return new qn(t,new rt(Xl,0,Math.round(e)))}static isGapFeature(e){return e.getLocus().chr===Xl}_flipIfReverseStrand(e){if(e.feature.getIsReverseStrand())return new an(e.feature,t(e.relativeEnd),t(e.relativeStart));return e;function t(a){return e.feature.getLength()-a}}getName(){return this._name}getFeatures(){return this._features.slice()}getTotalBases(){return this._totalBases}getIsValidBase(e){return 0<=e&&e<this._totalBases}getFeatureStart(e){const t=this._minCoordinateForFeature.get(e);if(t===void 0)throw new RangeError(`Feature "${e.getName()}" not in this navigation context`);return t}convertBaseToFeatureCoordinate(e){if(!this.getIsValidBase(e))throw new RangeError(`Base number ${e} is invalid.  Valid bases in this context: [0, ${this.getTotalBases()})`);const t=Xt.sortedLastIndex(this._sortedFeatureStarts,e)-1,a=this._features[t],o=e-this._sortedFeatureStarts[t];return new an(a,o,o+1)}convertFeatureSegmentToContextCoordinates(e){e=this._flipIfReverseStrand(e);const t=this.getFeatureStart(e.feature);return new Ne(t+e.relativeStart,t+e.relativeEnd)}convertGenomeIntervalToBases(e){const t=this._featuresForChr[e.chr]||[],a=[];for(const o of t){const s=new an(o).getGenomeOverlap(e);s&&a.push(this.convertFeatureSegmentToContextCoordinates(s))}return a}toGaplessCoordinate(e){const t=this.convertBaseToFeatureCoordinate(e),a=this._features.findIndex(f=>f===t.feature),o=this._features.slice(0,a).filter(In.isGapFeature);let s=Xt.sumBy(o,f=>f.getLength());return In.isGapFeature(t.feature)&&(s+=t.relativeStart),e-s}parse(e){const t=this._features.find(s=>s.getName()===e);if(t){const s=this.convertFeatureSegmentToContextCoordinates(new an(t)),f=.5*(s.start+s.end);return new Ne(f-3,f+3)}const a=rt.parse(e),o=this.convertGenomeIntervalToBases(a)[0];if(o)return o;throw new RangeError("Location unavailable in this context")}getFeaturesInInterval(e,t,a=!0){const o=new Ne(e,t),s=[];for(const f of this._features){if(!a&&In.isGapFeature(f))continue;const h=this.getFeatureStart(f),_=h+f.getLength(),d=new Ne(h,_).getOverlap(o);if(d){const c=d.start-h,D=d.end-h,x=new an(f,c,D);s.push(this._flipIfReverseStrand(x))}else if(s.length>0)break}return s}getLociInInterval(e,t){const o=this.getFeaturesInInterval(e,t,!1).map(s=>s.getLocus());return rt.mergeOverlaps(o)}hasFeatureWithName(e){return this._features.some(t=>t.name===e.name)}}const mu=0;class Ti{constructor(e,t=mu,a){ue(this,"_navContext");ue(this,"_startBase");ue(this,"_endBase");this._navContext=e,a===void 0&&(a=e.getTotalBases()),this.setRegion(t,a)}clone(){return new Ti(this._navContext,this._startBase,this._endBase)}getNavigationContext(){return this._navContext}getWidth(){return 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s;for(;(s=o.exec(n))!==null;)_(!0,s.index,s[0].length,e);if(t)return a;let f=0;const h=a.slice();for(const d of h)_(!1,f,d.index-f),f=d.index+d.length;return _(!1,f,n.length-f),a;function _(d,c,D,x=0){D>x&&a.push({isGap:d,index:c,length:D})}}function ao(n,e,t=!1){const a=t?-1:1,o=[];let s=e;for(const f of n)o.push(s),f!==va&&(s+=a);return o}class Og{constructor(e){ue(this,"sequence");ue(this,"_currentIndex");this.sequence=e,this._currentIndex=-1}reset(){this._currentIndex=0}getCurrentIndex(){return this._currentIndex}getIndexOfNextBase(){do this._currentIndex++;while(this.sequence.charAt(this._currentIndex)===va);return this._currentIndex}hasNextBase(){return this._currentIndex<this.sequence.length-1}advanceN(e){let t=this._currentIndex;for(let a=0;a<e;a++)t=this.getIndexOfNextBase();return t}}class uo extends an{constructor(t,a,o){super(t,a,o);ue(this,"feature");ue(this,"sequenceInterval");this.feature=t;const s=new 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h)a.push({contextBase:_[d.index],length:d.length})}return a}_placeSequenceSegments(e,t,a,o){const s=Yl(e,t);s.sort((h,_)=>h.index-_.index);let f=a;for(const h of s){const _=h.isGap?h.length:Du(e.substr(h.index,h.length)),d=o.basesToXWidth(_);h.xSpan=new Ne(f,f+d),f+=d}return s}_getQueryPieces(e){const t=[];for(const a of e){const{record:o,visiblePart:s}=a,f=o.getIsReverseStrandQuery(),h=s.getQuerySequence();let _;f?_=ao(h,s.getQueryLocusFine().end,!0):_=ao(h,s.getQueryLocusFine().start);const d=o.queryLocus.chr;for(const c of a.querySegments){const{isGap:D,index:x,length:m,xSpan:B}=c;if(D)continue;const F=_[x],I=Du(h.substr(x,m));let k;f?k=new rt(d,F-I,F):k=new rt(d,F,F+I),t.push({queryFeature:new qn(void 0,k,o.queryStrand),queryXSpan:B})}}return t}_makeQueryGenomeRegion(e,t,a){const o=e.slice().sort((d,c)=>d.queryXSpan.start-c.queryXSpan.start),s=[];let f=0,h=new rt("",-1,-1);for(const d of 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a=.5*(e.start+e.end);t=Math.abs(a-this.leftExtent)<Math.abs(a-this.rightExtent)?new Ne(this.leftExtent-e.getLength(),this.leftExtent):new Ne(this.rightExtent,this.rightExtent+e.getLength())}return this._placements.push(t),t.start<this.leftExtent&&(this.leftExtent=t.start-this.margin),t.end>this.rightExtent&&(this.rightExtent=t.end+this.margin),t}retrievePlacements(){return this._placements}}function R_(n){const e=Xt.sumBy(n,a=>.5*a.getLength()*(a.start+a.end)),t=Xt.sumBy(n,a=>a.getLength());return e/t}function N_(n,e){return n.chr!==e.chr?!1:n.end===e.start||e.end===n.start}class $_{}class L_{constructor(){this.signals=new Set,this.abortController=new AbortController}addSignal(e=new $_){if(this.signal.aborted)throw new Error("cannot add a signal, already aborted!");this.signals.add(e),e.aborted?this.handleAborted(e):typeof 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Io(n,e,t,a,o){this.static_tree=n,this.extra_bits=e,this.extra_base=t,this.elems=a,this.max_length=o,this.has_stree=n&&n.length}var xh,Eh,Ch;function To(n,e){this.dyn_tree=n,this.max_code=0,this.stat_desc=e}function Ah(n){return n<256?ka[n]:ka[256+(n>>>7)]}function Na(n,e){n.pending_buf[n.pending++]=e&255,n.pending_buf[n.pending++]=e>>>8&255}function Mt(n,e,t){n.bi_valid>Ao-t?(n.bi_buf|=e<<n.bi_valid&65535,Na(n,n.bi_buf),n.bi_buf=e>>Ao-n.bi_valid,n.bi_valid+=t-Ao):(n.bi_buf|=e<<n.bi_valid&65535,n.bi_valid+=t)}function Kn(n,e,t){Mt(n,t[e*2],t[e*2+1])}function Fh(n,e){var t=0;do t|=n&1,n>>>=1,t<<=1;while(--e>0);return t>>>1}function a2(n){n.bi_valid===16?(Na(n,n.bi_buf),n.bi_buf=0,n.bi_valid=0):n.bi_valid>=8&&(n.pending_buf[n.pending++]=n.bi_buf&255,n.bi_buf>>=8,n.bi_valid-=8)}function u2(n,e){var t=e.dyn_tree,a=e.max_code,o=e.stat_desc.static_tree,s=e.stat_desc.has_stree,f=e.stat_desc.extra_bits,h=e.stat_desc.extra_base,_=e.stat_desc.max_length,d,c,D,x,m,B,F=0;for(x=0;x<=ri;x++)n.bl_count[x]=0;for(t[n.heap[n.heap_max]*2+1]=0,d=n.heap_max+1;d<wh;d++)c=n.heap[d],x=t[t[c*2+1]*2+1]+1,x>_&&(x=_,F++),t[c*2+1]=x,!(c>a)&&(n.bl_count[x]++,m=0,c>=h&&(m=f[c-h]),B=t[c*2],n.opt_len+=B*(x+m),s&&(n.static_len+=B*(o[c*2+1]+m)));if(F!==0){do{for(x=_-1;n.bl_count[x]===0;)x--;n.bl_count[x]--,n.bl_count[x+1]+=2,n.bl_count[_]--,F-=2}while(F>0);for(x=_;x!==0;x--)for(c=n.bl_count[x];c!==0;)D=n.heap[--d],!(D>a)&&(t[D*2+1]!==x&&(n.opt_len+=(x-t[D*2+1])*t[D*2],t[D*2+1]=x),c--)}}function Bh(n,e,t){var a=new Array(ri+1),o=0,s,f;for(s=1;s<=ri;s++)a[s]=o=o+t[s-1]<<1;for(f=0;f<=e;f++){var h=n[f*2+1];h!==0&&(n[f*2]=Fh(a[h]++,h))}}function s2(){var n,e,t,a,o,s=new Array(ri+1);for(t=0,a=0;a<Eo-1;a++)for(So[a]=t,n=0;n<1<<Bo[a];n++)Ra[t++]=a;for(Ra[t-1]=a,o=0,a=0;a<16;a++)for(Fu[a]=o,n=0;n<1<<Au[a];n++)ka[o++]=a;for(o>>=7;a<Pi;a++)for(Fu[a]=o<<7,n=0;n<1<<Au[a]-7;n++)ka[256+o++]=a;for(e=0;e<=ri;e++)s[e]=0;for(n=0;n<=143;)lr[n*2+1]=8,n++,s[8]++;for(;n<=255;)lr[n*2+1]=9,n++,s[9]++;for(;n<=279;)lr[n*2+1]=7,n++,s[7]++;for(;n<=287;)lr[n*2+1]=8,n++,s[8]++;for(Bh(lr,Ia+1,s),n=0;n<Pi;n++)Ta[n*2+1]=5,Ta[n*2]=Fh(n,5);xh=new Io(lr,Bo,Sa+1,Ia,ri),Eh=new Io(Ta,Au,0,Pi,ri),Ch=new Io(new Array(0),r2,0,Co,n2)}function Sh(n){var e;for(e=0;e<Ia;e++)n.dyn_ltree[e*2]=0;for(e=0;e<Pi;e++)n.dyn_dtree[e*2]=0;for(e=0;e<Co;e++)n.bl_tree[e*2]=0;n.dyn_ltree[Fo*2]=1,n.opt_len=n.static_len=0,n.last_lit=n.matches=0}function Ih(n){n.bi_valid>8?Na(n,n.bi_buf):n.bi_valid>0&&(n.pending_buf[n.pending++]=n.bi_buf),n.bi_buf=0,n.bi_valid=0}function o2(n,e,t,a){Ih(n),Na(n,t),Na(n,~t),Y_.arraySet(n.pending_buf,n.window,e,t,n.pending),n.pending+=t}function Th(n,e,t,a){var o=e*2,s=t*2;return n[o]<n[s]||n[o]===n[s]&&a[e]<=a[t]}function ko(n,e,t){for(var a=n.heap[t],o=t<<1;o<=n.heap_len&&(o<n.heap_len&&Th(e,n.heap[o+1],n.heap[o],n.depth)&&o++,!Th(e,a,n.heap[o],n.depth));)n.heap[t]=n.heap[o],t=o,o<<=1;n.heap[t]=a}function kh(n,e,t){var a,o,s=0,f,h;if(n.last_lit!==0)do a=n.pending_buf[n.d_buf+s*2]<<8|n.pending_buf[n.d_buf+s*2+1],o=n.pending_buf[n.l_buf+s],s++,a===0?Kn(n,o,e):(f=Ra[o],Kn(n,f+Sa+1,e),h=Bo[f],h!==0&&(o-=So[f],Mt(n,o,h)),a--,f=Ah(a),Kn(n,f,t),h=Au[f],h!==0&&(a-=Fu[f],Mt(n,a,h)));while(s<n.last_lit);Kn(n,Fo,e)}function Ro(n,e){var t=e.dyn_tree,a=e.stat_desc.static_tree,o=e.stat_desc.has_stree,s=e.stat_desc.elems,f,h,_=-1,d;for(n.heap_len=0,n.heap_max=wh,f=0;f<s;f++)t[f*2]!==0?(n.heap[++n.heap_len]=_=f,n.depth[f]=0):t[f*2+1]=0;for(;n.heap_len<2;)d=n.heap[++n.heap_len]=_<2?++_:0,t[d*2]=1,n.depth[d]=0,n.opt_len--,o&&(n.static_len-=a[d*2+1]);for(e.max_code=_,f=n.heap_len>>1;f>=1;f--)ko(n,t,f);d=s;do f=n.heap[1],n.heap[1]=n.heap[n.heap_len--],ko(n,t,1),h=n.heap[1],n.heap[--n.heap_max]=f,n.heap[--n.heap_max]=h,t[d*2]=t[f*2]+t[h*2],n.depth[d]=(n.depth[f]>=n.depth[h]?n.depth[f]:n.depth[h])+1,t[f*2+1]=t[h*2+1]=d,n.heap[1]=d++,ko(n,t,1);while(n.heap_len>=2);n.heap[--n.heap_max]=n.heap[1],u2(n,e),Bh(t,_,n.bl_count)}function Rh(n,e,t){var a,o=-1,s,f=e[0*2+1],h=0,_=7,d=4;for(f===0&&(_=138,d=3),e[(t+1)*2+1]=65535,a=0;a<=t;a++)s=f,f=e[(a+1)*2+1],!(++h<_&&s===f)&&(h<d?n.bl_tree[s*2]+=h:s!==0?(s!==o&&n.bl_tree[s*2]++,n.bl_tree[bh*2]++):h<=10?n.bl_tree[mh*2]++:n.bl_tree[Dh*2]++,h=0,o=s,f===0?(_=138,d=3):s===f?(_=6,d=3):(_=7,d=4))}function Nh(n,e,t){var a,o=-1,s,f=e[0*2+1],h=0,_=7,d=4;for(f===0&&(_=138,d=3),a=0;a<=t;a++)if(s=f,f=e[(a+1)*2+1],!(++h<_&&s===f)){if(h<d)do Kn(n,s,n.bl_tree);while(--h!==0);else s!==0?(s!==o&&(Kn(n,s,n.bl_tree),h--),Kn(n,bh,n.bl_tree),Mt(n,h-3,2)):h<=10?(Kn(n,mh,n.bl_tree),Mt(n,h-3,3)):(Kn(n,Dh,n.bl_tree),Mt(n,h-11,7));h=0,o=s,f===0?(_=138,d=3):s===f?(_=6,d=3):(_=7,d=4)}}function f2(n){var e;for(Rh(n,n.dyn_ltree,n.l_desc.max_code),Rh(n,n.dyn_dtree,n.d_desc.max_code),Ro(n,n.bl_desc),e=Co-1;e>=3&&n.bl_tree[yh[e]*2+1]===0;e--);return n.opt_len+=3*(e+1)+5+5+4,e}function l2(n,e,t,a){var o;for(Mt(n,e-257,5),Mt(n,t-1,5),Mt(n,a-4,4),o=0;o<a;o++)Mt(n,n.bl_tree[yh[o]*2+1],3);Nh(n,n.dyn_ltree,e-1),Nh(n,n.dyn_dtree,t-1)}function h2(n){var e=4093624447,t;for(t=0;t<=31;t++,e>>>=1)if(e&1&&n.dyn_ltree[t*2]!==0)return gh;if(n.dyn_ltree[9*2]!==0||n.dyn_ltree[10*2]!==0||n.dyn_ltree[13*2]!==0)return _h;for(t=32;t<Sa;t++)if(n.dyn_ltree[t*2]!==0)return _h;return gh}var $h=!1;function c2(n){$h||(s2(),$h=!0),n.l_desc=new To(n.dyn_ltree,xh),n.d_desc=new To(n.dyn_dtree,Eh),n.bl_desc=new To(n.bl_tree,Ch),n.bi_buf=0,n.bi_valid=0,Sh(n)}function Lh(n,e,t,a){Mt(n,(j_<<1)+(a?1:0),3),o2(n,e,t)}function d2(n){Mt(n,vh<<1,3),Kn(n,Fo,lr),a2(n)}function p2(n,e,t,a){var o,s,f=0;n.level>0?(n.strm.data_type===J_&&(n.strm.data_type=h2(n)),Ro(n,n.l_desc),Ro(n,n.d_desc),f=f2(n),o=n.opt_len+3+7>>>3,s=n.static_len+3+7>>>3,s<=o&&(o=s)):o=s=t+5,t+4<=o&&e!==-1?Lh(n,e,t,a):n.strategy===Q_||s===o?(Mt(n,(vh<<1)+(a?1:0),3),kh(n,lr,Ta)):(Mt(n,(z_<<1)+(a?1:0),3),l2(n,n.l_desc.max_code+1,n.d_desc.max_code+1,f+1),kh(n,n.dyn_ltree,n.dyn_dtree)),Sh(n),a&&Ih(n)}function g2(n,e,t){return n.pending_buf[n.d_buf+n.last_lit*2]=e>>>8&255,n.pending_buf[n.d_buf+n.last_lit*2+1]=e&255,n.pending_buf[n.l_buf+n.last_lit]=t&255,n.last_lit++,e===0?n.dyn_ltree[t*2]++:(n.matches++,e--,n.dyn_ltree[(Ra[t]+Sa+1)*2]++,n.dyn_dtree[Ah(e)*2]++),n.last_lit===n.lit_bufsize-1}Li._tr_init=c2,Li._tr_stored_block=Lh,Li._tr_flush_block=p2,Li._tr_tally=g2,Li._tr_align=d2;function _2(n,e,t,a){for(var o=n&65535|0,s=n>>>16&65535|0,f=0;t!==0;){f=t>2e3?2e3:t,t-=f;do o=o+e[a++]|0,s=s+o|0;while(--f);o%=65521,s%=65521}return o|s<<16|0}var Oh=_2;function v2(){for(var n,e=[],t=0;t<256;t++){n=t;for(var a=0;a<8;a++)n=n&1?3988292384^n>>>1:n>>>1;e[t]=n}return e}var w2=v2();function b2(n,e,t,a){var o=w2,s=a+t;n^=-1;for(var f=a;f<s;f++)n=n>>>8^o[(n^e[f])&255];return n^-1}var Ph=b2,No={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible version"},Tt=fr,sn=Li,Mh=Oh,Ir=Ph,m2=No,ii=0,D2=1,y2=3,Tr=4,Uh=5,Yn=0,Wh=1,on=-2,x2=-3,$o=-5,E2=-1,C2=1,Bu=2,A2=3,F2=4,B2=0,S2=2,Su=8,I2=9,T2=15,k2=8,R2=29,N2=256,Lo=N2+1+R2,$2=30,L2=19,O2=2*Lo+1,P2=15,Ee=3,kr=258,kn=kr+Ee+1,M2=32,Iu=42,Oo=69,Tu=73,ku=91,Ru=103,ai=113,$a=666,ct=1,La=2,ui=3,Mi=4,U2=3;function Rr(n,e){return n.msg=m2[e],e}function Gh(n){return(n<<1)-(n>4?9:0)}function Nr(n){for(var e=n.length;--e>=0;)n[e]=0}function $r(n){var e=n.state,t=e.pending;t>n.avail_out&&(t=n.avail_out),t!==0&&(Tt.arraySet(n.output,e.pending_buf,e.pending_out,t,n.next_out),n.next_out+=t,e.pending_out+=t,n.total_out+=t,n.avail_out-=t,e.pending-=t,e.pending===0&&(e.pending_out=0))}function mt(n,e){sn._tr_flush_block(n,n.block_start>=0?n.block_start:-1,n.strstart-n.block_start,e),n.block_start=n.strstart,$r(n.strm)}function Se(n,e){n.pending_buf[n.pending++]=e}function Oa(n,e){n.pending_buf[n.pending++]=e>>>8&255,n.pending_buf[n.pending++]=e&255}function W2(n,e,t,a){var o=n.avail_in;return o>a&&(o=a),o===0?0:(n.avail_in-=o,Tt.arraySet(e,n.input,n.next_in,o,t),n.state.wrap===1?n.adler=Mh(n.adler,e,o,t):n.state.wrap===2&&(n.adler=Ir(n.adler,e,o,t)),n.next_in+=o,n.total_in+=o,o)}function qh(n,e){var t=n.max_chain_length,a=n.strstart,o,s,f=n.prev_length,h=n.nice_match,_=n.strstart>n.w_size-kn?n.strstart-(n.w_size-kn):0,d=n.window,c=n.w_mask,D=n.prev,x=n.strstart+kr,m=d[a+f-1],B=d[a+f];n.prev_length>=n.good_match&&(t>>=2),h>n.lookahead&&(h=n.lookahead);do if(o=e,!(d[o+f]!==B||d[o+f-1]!==m||d[o]!==d[a]||d[++o]!==d[a+1])){a+=2,o++;do;while(d[++a]===d[++o]&&d[++a]===d[++o]&&d[++a]===d[++o]&&d[++a]===d[++o]&&d[++a]===d[++o]&&d[++a]===d[++o]&&d[++a]===d[++o]&&d[++a]===d[++o]&&a<x);if(s=kr-(x-a),a=x-kr,s>f){if(n.match_start=e,f=s,s>=h)break;m=d[a+f-1],B=d[a+f]}}while((e=D[e&c])>_&&--t!==0);return f<=n.lookahead?f:n.lookahead}function si(n){var e=n.w_size,t,a,o,s,f;do{if(s=n.window_size-n.lookahead-n.strstart,n.strstart>=e+(e-kn)){Tt.arraySet(n.window,n.window,e,e,0),n.match_start-=e,n.strstart-=e,n.block_start-=e,a=n.hash_size,t=a;do o=n.head[--t],n.head[t]=o>=e?o-e:0;while(--a);a=e,t=a;do o=n.prev[--t],n.prev[t]=o>=e?o-e:0;while(--a);s+=e}if(n.strm.avail_in===0)break;if(a=W2(n.strm,n.window,n.strstart+n.lookahead,s),n.lookahead+=a,n.lookahead+n.insert>=Ee)for(f=n.strstart-n.insert,n.ins_h=n.window[f],n.ins_h=(n.ins_h<<n.hash_shift^n.window[f+1])&n.hash_mask;n.insert&&(n.ins_h=(n.ins_h<<n.hash_shift^n.window[f+Ee-1])&n.hash_mask,n.prev[f&n.w_mask]=n.head[n.ins_h],n.head[n.ins_h]=f,f++,n.insert--,!(n.lookahead+n.insert<Ee)););}while(n.lookahead<kn&&n.strm.avail_in!==0)}function G2(n,e){var t=65535;for(t>n.pending_buf_size-5&&(t=n.pending_buf_size-5);;){if(n.lookahead<=1){if(si(n),n.lookahead===0&&e===ii)return ct;if(n.lookahead===0)break}n.strstart+=n.lookahead,n.lookahead=0;var a=n.block_start+t;if((n.strstart===0||n.strstart>=a)&&(n.lookahead=n.strstart-a,n.strstart=a,mt(n,!1),n.strm.avail_out===0)||n.strstart-n.block_start>=n.w_size-kn&&(mt(n,!1),n.strm.avail_out===0))return ct}return n.insert=0,e===Tr?(mt(n,!0),n.strm.avail_out===0?ui:Mi):(n.strstart>n.block_start&&(mt(n,!1),n.strm.avail_out===0),ct)}function Po(n,e){for(var t,a;;){if(n.lookahead<kn){if(si(n),n.lookahead<kn&&e===ii)return ct;if(n.lookahead===0)break}if(t=0,n.lookahead>=Ee&&(n.ins_h=(n.ins_h<<n.hash_shift^n.window[n.strstart+Ee-1])&n.hash_mask,t=n.prev[n.strstart&n.w_mask]=n.head[n.ins_h],n.head[n.ins_h]=n.strstart),t!==0&&n.strstart-t<=n.w_size-kn&&(n.match_length=qh(n,t)),n.match_length>=Ee)if(a=sn._tr_tally(n,n.strstart-n.match_start,n.match_length-Ee),n.lookahead-=n.match_length,n.match_length<=n.max_lazy_match&&n.lookahead>=Ee){n.match_length--;do n.strstart++,n.ins_h=(n.ins_h<<n.hash_shift^n.window[n.strstart+Ee-1])&n.hash_mask,t=n.prev[n.strstart&n.w_mask]=n.head[n.ins_h],n.head[n.ins_h]=n.strstart;while(--n.match_length!==0);n.strstart++}else n.strstart+=n.match_length,n.match_length=0,n.ins_h=n.window[n.strstart],n.ins_h=(n.ins_h<<n.hash_shift^n.window[n.strstart+1])&n.hash_mask;else a=sn._tr_tally(n,0,n.window[n.strstart]),n.lookahead--,n.strstart++;if(a&&(mt(n,!1),n.strm.avail_out===0))return ct}return n.insert=n.strstart<Ee-1?n.strstart:Ee-1,e===Tr?(mt(n,!0),n.strm.avail_out===0?ui:Mi):n.last_lit&&(mt(n,!1),n.strm.avail_out===0)?ct:La}function Ui(n,e){for(var t,a,o;;){if(n.lookahead<kn){if(si(n),n.lookahead<kn&&e===ii)return ct;if(n.lookahead===0)break}if(t=0,n.lookahead>=Ee&&(n.ins_h=(n.ins_h<<n.hash_shift^n.window[n.strstart+Ee-1])&n.hash_mask,t=n.prev[n.strstart&n.w_mask]=n.head[n.ins_h],n.head[n.ins_h]=n.strstart),n.prev_length=n.match_length,n.prev_match=n.match_start,n.match_length=Ee-1,t!==0&&n.prev_length<n.max_lazy_match&&n.strstart-t<=n.w_size-kn&&(n.match_length=qh(n,t),n.match_length<=5&&(n.strategy===C2||n.match_length===Ee&&n.strstart-n.match_start>4096)&&(n.match_length=Ee-1)),n.prev_length>=Ee&&n.match_length<=n.prev_length){o=n.strstart+n.lookahead-Ee,a=sn._tr_tally(n,n.strstart-1-n.prev_match,n.prev_length-Ee),n.lookahead-=n.prev_length-1,n.prev_length-=2;do++n.strstart<=o&&(n.ins_h=(n.ins_h<<n.hash_shift^n.window[n.strstart+Ee-1])&n.hash_mask,t=n.prev[n.strstart&n.w_mask]=n.head[n.ins_h],n.head[n.ins_h]=n.strstart);while(--n.prev_length!==0);if(n.match_available=0,n.match_length=Ee-1,n.strstart++,a&&(mt(n,!1),n.strm.avail_out===0))return ct}else if(n.match_available){if(a=sn._tr_tally(n,0,n.window[n.strstart-1]),a&&mt(n,!1),n.strstart++,n.lookahead--,n.strm.avail_out===0)return ct}else n.match_available=1,n.strstart++,n.lookahead--}return n.match_available&&(a=sn._tr_tally(n,0,n.window[n.strstart-1]),n.match_available=0),n.insert=n.strstart<Ee-1?n.strstart:Ee-1,e===Tr?(mt(n,!0),n.strm.avail_out===0?ui:Mi):n.last_lit&&(mt(n,!1),n.strm.avail_out===0)?ct:La}function q2(n,e){for(var t,a,o,s,f=n.window;;){if(n.lookahead<=kr){if(si(n),n.lookahead<=kr&&e===ii)return ct;if(n.lookahead===0)break}if(n.match_length=0,n.lookahead>=Ee&&n.strstart>0&&(o=n.strstart-1,a=f[o],a===f[++o]&&a===f[++o]&&a===f[++o])){s=n.strstart+kr;do;while(a===f[++o]&&a===f[++o]&&a===f[++o]&&a===f[++o]&&a===f[++o]&&a===f[++o]&&a===f[++o]&&a===f[++o]&&o<s);n.match_length=kr-(s-o),n.match_length>n.lookahead&&(n.match_length=n.lookahead)}if(n.match_length>=Ee?(t=sn._tr_tally(n,1,n.match_length-Ee),n.lookahead-=n.match_length,n.strstart+=n.match_length,n.match_length=0):(t=sn._tr_tally(n,0,n.window[n.strstart]),n.lookahead--,n.strstart++),t&&(mt(n,!1),n.strm.avail_out===0))return ct}return n.insert=0,e===Tr?(mt(n,!0),n.strm.avail_out===0?ui:Mi):n.last_lit&&(mt(n,!1),n.strm.avail_out===0)?ct:La}function H2(n,e){for(var t;;){if(n.lookahead===0&&(si(n),n.lookahead===0)){if(e===ii)return ct;break}if(n.match_length=0,t=sn._tr_tally(n,0,n.window[n.strstart]),n.lookahead--,n.strstart++,t&&(mt(n,!1),n.strm.avail_out===0))return ct}return n.insert=0,e===Tr?(mt(n,!0),n.strm.avail_out===0?ui:Mi):n.last_lit&&(mt(n,!1),n.strm.avail_out===0)?ct:La}function Qn(n,e,t,a,o){this.good_length=n,this.max_lazy=e,this.nice_length=t,this.max_chain=a,this.func=o}var Wi;Wi=[new Qn(0,0,0,0,G2),new Qn(4,4,8,4,Po),new Qn(4,5,16,8,Po),new Qn(4,6,32,32,Po),new Qn(4,4,16,16,Ui),new Qn(8,16,32,32,Ui),new Qn(8,16,128,128,Ui),new Qn(8,32,128,256,Ui),new Qn(32,128,258,1024,Ui),new Qn(32,258,258,4096,Ui)];function V2(n){n.window_size=2*n.w_size,Nr(n.head),n.max_lazy_match=Wi[n.level].max_lazy,n.good_match=Wi[n.level].good_length,n.nice_match=Wi[n.level].nice_length,n.max_chain_length=Wi[n.level].max_chain,n.strstart=0,n.block_start=0,n.lookahead=0,n.insert=0,n.match_length=n.prev_length=Ee-1,n.match_available=0,n.ins_h=0}function Z2(){this.strm=null,this.status=0,this.pending_buf=null,this.pending_buf_size=0,this.pending_out=0,this.pending=0,this.wrap=0,this.gzhead=null,this.gzindex=0,this.method=Su,this.last_flush=-1,this.w_size=0,this.w_bits=0,this.w_mask=0,this.window=null,this.window_size=0,this.prev=null,this.head=null,this.ins_h=0,this.hash_size=0,this.hash_bits=0,this.hash_mask=0,this.hash_shift=0,this.block_start=0,this.match_length=0,this.prev_match=0,this.match_available=0,this.strstart=0,this.match_start=0,this.lookahead=0,this.prev_length=0,this.max_chain_length=0,this.max_lazy_match=0,this.level=0,this.strategy=0,this.good_match=0,this.nice_match=0,this.dyn_ltree=new Tt.Buf16(O2*2),this.dyn_dtree=new Tt.Buf16((2*$2+1)*2),this.bl_tree=new Tt.Buf16((2*L2+1)*2),Nr(this.dyn_ltree),Nr(this.dyn_dtree),Nr(this.bl_tree),this.l_desc=null,this.d_desc=null,this.bl_desc=null,this.bl_count=new Tt.Buf16(P2+1),this.heap=new Tt.Buf16(2*Lo+1),Nr(this.heap),this.heap_len=0,this.heap_max=0,this.depth=new Tt.Buf16(2*Lo+1),Nr(this.depth),this.l_buf=0,this.lit_bufsize=0,this.last_lit=0,this.d_buf=0,this.opt_len=0,this.static_len=0,this.matches=0,this.insert=0,this.bi_buf=0,this.bi_valid=0}function Hh(n){var e;return!n||!n.state?Rr(n,on):(n.total_in=n.total_out=0,n.data_type=S2,e=n.state,e.pending=0,e.pending_out=0,e.wrap<0&&(e.wrap=-e.wrap),e.status=e.wrap?Iu:ai,n.adler=e.wrap===2?0:1,e.last_flush=ii,sn._tr_init(e),Yn)}function Vh(n){var e=Hh(n);return e===Yn&&V2(n.state),e}function X2(n,e){return!n||!n.state||n.state.wrap!==2?on:(n.state.gzhead=e,Yn)}function Zh(n,e,t,a,o,s){if(!n)return on;var f=1;if(e===E2&&(e=6),a<0?(f=0,a=-a):a>15&&(f=2,a-=16),o<1||o>I2||t!==Su||a<8||a>15||e<0||e>9||s<0||s>F2)return Rr(n,on);a===8&&(a=9);var h=new Z2;return n.state=h,h.strm=n,h.wrap=f,h.gzhead=null,h.w_bits=a,h.w_size=1<<h.w_bits,h.w_mask=h.w_size-1,h.hash_bits=o+7,h.hash_size=1<<h.hash_bits,h.hash_mask=h.hash_size-1,h.hash_shift=~~((h.hash_bits+Ee-1)/Ee),h.window=new Tt.Buf8(h.w_size*2),h.head=new 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f=Su+(a.w_bits-8<<4)<<8,h=-1;a.strategy>=Bu||a.level<2?h=0:a.level<6?h=1:a.level===6?h=2:h=3,f|=h<<6,a.strstart!==0&&(f|=M2),f+=31-f%31,a.status=ai,Oa(a,f),a.strstart!==0&&(Oa(a,n.adler>>>16),Oa(a,n.adler&65535)),n.adler=1}if(a.status===Oo)if(a.gzhead.extra){for(o=a.pending;a.gzindex<(a.gzhead.extra.length&65535)&&!(a.pending===a.pending_buf_size&&(a.gzhead.hcrc&&a.pending>o&&(n.adler=Ir(n.adler,a.pending_buf,a.pending-o,o)),$r(n),o=a.pending,a.pending===a.pending_buf_size));)Se(a,a.gzhead.extra[a.gzindex]&255),a.gzindex++;a.gzhead.hcrc&&a.pending>o&&(n.adler=Ir(n.adler,a.pending_buf,a.pending-o,o)),a.gzindex===a.gzhead.extra.length&&(a.gzindex=0,a.status=Tu)}else 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e!==Tr?Yn:a.wrap<=0?Wh:(a.wrap===2?(Se(a,n.adler&255),Se(a,n.adler>>8&255),Se(a,n.adler>>16&255),Se(a,n.adler>>24&255),Se(a,n.total_in&255),Se(a,n.total_in>>8&255),Se(a,n.total_in>>16&255),Se(a,n.total_in>>24&255)):(Oa(a,n.adler>>>16),Oa(a,n.adler&65535)),$r(n),a.wrap>0&&(a.wrap=-a.wrap),a.pending!==0?Yn:Wh)}function Q2(n){var e;return!n||!n.state?on:(e=n.state.status,e!==Iu&&e!==Oo&&e!==Tu&&e!==ku&&e!==Ru&&e!==ai&&e!==$a?Rr(n,on):(n.state=null,e===ai?Rr(n,x2):Yn))}function J2(n,e){var t=e.length,a,o,s,f,h,_,d,c;if(!n||!n.state||(a=n.state,f=a.wrap,f===2||f===1&&a.status!==Iu||a.lookahead))return on;for(f===1&&(n.adler=Mh(n.adler,e,t,0)),a.wrap=0,t>=a.w_size&&(f===0&&(Nr(a.head),a.strstart=0,a.block_start=0,a.insert=0),c=new Tt.Buf8(a.w_size),Tt.arraySet(c,e,t-a.w_size,a.w_size,0),e=c,t=a.w_size),h=n.avail_in,_=n.next_in,d=n.input,n.avail_in=t,n.next_in=0,n.input=e,si(a);a.lookahead>=Ee;){o=a.strstart,s=a.lookahead-(Ee-1);do 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e,t,a,o,s,f=n.length,h=0;for(o=0;o<f;o++)t=n.charCodeAt(o),(t&64512)===55296&&o+1<f&&(a=n.charCodeAt(o+1),(a&64512)===56320&&(t=65536+(t-55296<<10)+(a-56320),o++)),h+=t<128?1:t<2048?2:t<65536?3:4;for(e=new Nu.Buf8(h),s=0,o=0;s<h;o++)t=n.charCodeAt(o),(t&64512)===55296&&o+1<f&&(a=n.charCodeAt(o+1),(a&64512)===56320&&(t=65536+(t-55296<<10)+(a-56320),o++)),t<128?e[s++]=t:t<2048?(e[s++]=192|t>>>6,e[s++]=128|t&63):t<65536?(e[s++]=224|t>>>12,e[s++]=128|t>>>6&63,e[s++]=128|t&63):(e[s++]=240|t>>>18,e[s++]=128|t>>>12&63,e[s++]=128|t>>>6&63,e[s++]=128|t&63);return e};function Yh(n,e){if(e<65534&&(n.subarray&&Kh||!n.subarray&&Xh))return String.fromCharCode.apply(null,Nu.shrinkBuf(n,e));for(var t="",a=0;a<e;a++)t+=String.fromCharCode(n[a]);return t}oi.buf2binstring=function(n){return Yh(n,n.length)},oi.binstring2buf=function(n){for(var e=new Nu.Buf8(n.length),t=0,a=e.length;t<a;t++)e[t]=n.charCodeAt(t);return e},oi.buf2string=function(n,e){var t,a,o,s,f=e||n.length,h=new 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e=this.options;e.raw&&e.windowBits>0?e.windowBits=-e.windowBits:e.gzip&&e.windowBits>0&&e.windowBits<16&&(e.windowBits+=16),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new z2,this.strm.avail_out=0;var t=Ma.deflateInit2(this.strm,e.level,e.method,e.windowBits,e.memLevel,e.strategy);if(t!==Gi)throw new Error(Uo[t]);if(e.header&&Ma.deflateSetHeader(this.strm,e.header),e.dictionary){var a;if(typeof e.dictionary=="string"?a=Mo.string2buf(e.dictionary):Jh.call(e.dictionary)==="[object ArrayBuffer]"?a=new Uint8Array(e.dictionary):a=e.dictionary,t=Ma.deflateSetDictionary(this.strm,a),t!==Gi)throw new Error(Uo[t]);this._dict_set=!0}}fi.prototype.push=function(n,e){var t=this.strm,a=this.options.chunkSize,o,s;if(this.ended)return!1;s=e===~~e?e:e===!0?Wo:ev,typeof n=="string"?t.input=Mo.string2buf(n):Jh.call(n)==="[object ArrayBuffer]"?t.input=new Uint8Array(n):t.input=n,t.next_in=0,t.avail_in=t.input.length;do{if(t.avail_out===0&&(t.output=new Ua.Buf8(a),t.next_out=0,t.avail_out=a),o=Ma.deflate(t,s),o!==jh&&o!==Gi)return this.onEnd(o),this.ended=!0,!1;(t.avail_out===0||t.avail_in===0&&(s===Wo||s===zh))&&(this.options.to==="string"?this.onData(Mo.buf2binstring(Ua.shrinkBuf(t.output,t.next_out))):this.onData(Ua.shrinkBuf(t.output,t.next_out)))}while((t.avail_in>0||t.avail_out===0)&&o!==jh);return s===Wo?(o=Ma.deflateEnd(this.strm),this.onEnd(o),this.ended=!0,o===Gi):(s===zh&&(this.onEnd(Gi),t.avail_out=0),!0)},fi.prototype.onData=function(n){this.chunks.push(n)},fi.prototype.onEnd=function(n){n===Gi&&(this.options.to==="string"?this.result=this.chunks.join(""):this.result=Ua.flattenChunks(this.chunks)),this.chunks=[],this.err=n,this.msg=this.strm.msg};function Go(n,e){var t=new fi(e);if(t.push(n,!0),t.err)throw t.msg||Uo[t.err];return t.result}function iv(n,e){return e=e||{},e.raw=!0,Go(n,e)}function av(n,e){return e=e||{},e.gzip=!0,Go(n,e)}Ba.Deflate=fi,Ba.deflate=Go,Ba.deflateRaw=iv,Ba.gzip=av;var Wa={},Rn={},$u=30,uv=12,sv=function(e,t){var a,o,s,f,h,_,d,c,D,x,m,B,F,I,k,U,$,S,L,W,N,q,H,Z,Y;a=e.state,o=e.next_in,Z=e.input,s=o+(e.avail_in-5),f=e.next_out,Y=e.output,h=f-(t-e.avail_out),_=f+(e.avail_out-257),d=a.dmax,c=a.wsize,D=a.whave,x=a.wnext,m=a.window,B=a.hold,F=a.bits,I=a.lencode,k=a.distcode,U=(1<<a.lenbits)-1,$=(1<<a.distbits)-1;e:do{F<15&&(B+=Z[o++]<<F,F+=8,B+=Z[o++]<<F,F+=8),S=I[B&U];t:for(;;){if(L=S>>>24,B>>>=L,F-=L,L=S>>>16&255,L===0)Y[f++]=S&65535;else if(L&16){W=S&65535,L&=15,L&&(F<L&&(B+=Z[o++]<<F,F+=8),W+=B&(1<<L)-1,B>>>=L,F-=L),F<15&&(B+=Z[o++]<<F,F+=8,B+=Z[o++]<<F,F+=8),S=k[B&$];n:for(;;){if(L=S>>>24,B>>>=L,F-=L,L=S>>>16&255,L&16){if(N=S&65535,L&=15,F<L&&(B+=Z[o++]<<F,F+=8,F<L&&(B+=Z[o++]<<F,F+=8)),N+=B&(1<<L)-1,N>d){e.msg="invalid distance too far back",a.mode=$u;break e}if(B>>>=L,F-=L,L=f-h,N>L){if(L=N-L,L>D&&a.sane){e.msg="invalid distance too far back",a.mode=$u;break e}if(q=0,H=m,x===0){if(q+=c-L,L<W){W-=L;do Y[f++]=m[q++];while(--L);q=f-N,H=Y}}else if(x<L){if(q+=c+x-L,L-=x,L<W){W-=L;do Y[f++]=m[q++];while(--L);if(q=0,x<W){L=x,W-=L;do Y[f++]=m[q++];while(--L);q=f-N,H=Y}}}else if(q+=x-L,L<W){W-=L;do Y[f++]=m[q++];while(--L);q=f-N,H=Y}for(;W>2;)Y[f++]=H[q++],Y[f++]=H[q++],Y[f++]=H[q++],W-=3;W&&(Y[f++]=H[q++],W>1&&(Y[f++]=H[q++]))}else{q=f-N;do Y[f++]=Y[q++],Y[f++]=Y[q++],Y[f++]=Y[q++],W-=3;while(W>2);W&&(Y[f++]=Y[q++],W>1&&(Y[f++]=Y[q++]))}}else if(L&64){e.msg="invalid distance code",a.mode=$u;break e}else{S=k[(S&65535)+(B&(1<<L)-1)];continue n}break}}else if(L&64)if(L&32){a.mode=uv;break e}else{e.msg="invalid literal/length code",a.mode=$u;break e}else{S=I[(S&65535)+(B&(1<<L)-1)];continue t}break}}while(o<s&&f<_);W=F>>3,o-=W,F-=W<<3,B&=(1<<F)-1,e.next_in=o,e.next_out=f,e.avail_in=o<s?5+(s-o):5-(o-s),e.avail_out=f<_?257+(_-f):257-(f-_),a.hold=B,a.bits=F},e0=fr,qi=15,t0=852,n0=592,r0=0,qo=1,i0=2,ov=[3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0],fv=[16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78],lv=[1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0],hv=[16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64],cv=function(e,t,a,o,s,f,h,_){var d=_.bits,c=0,D=0,x=0,m=0,B=0,F=0,I=0,k=0,U=0,$=0,S,L,W,N,q,H=null,Z=0,Y,re=new e0.Buf16(qi+1),se=new e0.Buf16(qi+1),fe=null,ce=0,Me,Fe,Ce;for(c=0;c<=qi;c++)re[c]=0;for(D=0;D<o;D++)re[t[a+D]]++;for(B=d,m=qi;m>=1&&re[m]===0;m--);if(B>m&&(B=m),m===0)return s[f++]=1<<24|64<<16|0,s[f++]=1<<24|64<<16|0,_.bits=1,0;for(x=1;x<m&&re[x]===0;x++);for(B<x&&(B=x),k=1,c=1;c<=qi;c++)if(k<<=1,k-=re[c],k<0)return-1;if(k>0&&(e===r0||m!==1))return-1;for(se[1]=0,c=1;c<qi;c++)se[c+1]=se[c]+re[c];for(D=0;D<o;D++)t[a+D]!==0&&(h[se[t[a+D]]++]=D);if(e===r0?(H=fe=h,Y=19):e===qo?(H=ov,Z-=257,fe=fv,ce-=257,Y=256):(H=lv,fe=hv,Y=-1),$=0,D=0,c=x,q=f,F=B,I=0,W=-1,U=1<<B,N=U-1,e===qo&&U>t0||e===i0&&U>n0)return 1;for(;;){Me=c-I,h[D]<Y?(Fe=0,Ce=h[D]):h[D]>Y?(Fe=fe[ce+h[D]],Ce=H[Z+h[D]]):(Fe=96,Ce=0),S=1<<c-I,L=1<<F,x=L;do L-=S,s[q+($>>I)+L]=Me<<24|Fe<<16|Ce|0;while(L!==0);for(S=1<<c-1;$&S;)S>>=1;if(S!==0?($&=S-1,$+=S):$=0,D++,--re[c]===0){if(c===m)break;c=t[a+h[D]]}if(c>B&&($&N)!==W){for(I===0&&(I=B),q+=x,F=c-I,k=1<<F;F+I<m&&(k-=re[F+I],!(k<=0));)F++,k<<=1;if(U+=1<<F,e===qo&&U>t0||e===i0&&U>n0)return 1;W=$&N,s[W]=B<<24|F<<16|q-f|0}}return $!==0&&(s[q+$]=c-I<<24|64<<16|0),_.bits=B,0},Kt=fr,Ho=Oh,Jn=Ph,dv=sv,Ga=cv,pv=0,a0=1,u0=2,s0=4,gv=5,Lu=6,li=0,_v=1,vv=2,fn=-2,o0=-3,f0=-4,wv=-5,l0=8,h0=1,c0=2,d0=3,p0=4,g0=5,_0=6,v0=7,w0=8,b0=9,m0=10,Ou=11,hr=12,Vo=13,D0=14,Zo=15,y0=16,x0=17,E0=18,C0=19,Pu=20,Mu=21,A0=22,F0=23,B0=24,S0=25,I0=26,Xo=27,T0=28,k0=29,Ye=30,R0=31,bv=32,mv=852,Dv=592,yv=15,xv=yv;function N0(n){return(n>>>24&255)+(n>>>8&65280)+((n&65280)<<8)+((n&255)<<24)}function Ev(){this.mode=0,this.last=!1,this.wrap=0,this.havedict=!1,this.flags=0,this.dmax=0,this.check=0,this.total=0,this.head=null,this.wbits=0,this.wsize=0,this.whave=0,this.wnext=0,this.window=null,this.hold=0,this.bits=0,this.length=0,this.offset=0,this.extra=0,this.lencode=null,this.distcode=null,this.lenbits=0,this.distbits=0,this.ncode=0,this.nlen=0,this.ndist=0,this.have=0,this.next=null,this.lens=new Kt.Buf16(320),this.work=new Kt.Buf16(288),this.lendyn=null,this.distdyn=null,this.sane=0,this.back=0,this.was=0}function $0(n){var e;return!n||!n.state?fn:(e=n.state,n.total_in=n.total_out=e.total=0,n.msg="",e.wrap&&(n.adler=e.wrap&1),e.mode=h0,e.last=0,e.havedict=0,e.dmax=32768,e.head=null,e.hold=0,e.bits=0,e.lencode=e.lendyn=new Kt.Buf32(mv),e.distcode=e.distdyn=new Kt.Buf32(Dv),e.sane=1,e.back=-1,li)}function L0(n){var e;return!n||!n.state?fn:(e=n.state,e.wsize=0,e.whave=0,e.wnext=0,$0(n))}function O0(n,e){var t,a;return!n||!n.state||(a=n.state,e<0?(t=0,e=-e):(t=(e>>4)+1,e<48&&(e&=15)),e&&(e<8||e>15))?fn:(a.window!==null&&a.wbits!==e&&(a.window=null),a.wrap=t,a.wbits=e,L0(n))}function P0(n,e){var t,a;return n?(a=new Ev,n.state=a,a.window=null,t=O0(n,e),t!==li&&(n.state=null),t):fn}function Cv(n){return P0(n,xv)}var M0=!0,Ko,Yo;function Av(n){if(M0){var e;for(Ko=new Kt.Buf32(512),Yo=new Kt.Buf32(32),e=0;e<144;)n.lens[e++]=8;for(;e<256;)n.lens[e++]=9;for(;e<280;)n.lens[e++]=7;for(;e<288;)n.lens[e++]=8;for(Ga(a0,n.lens,0,288,Ko,0,n.work,{bits:9}),e=0;e<32;)n.lens[e++]=5;Ga(u0,n.lens,0,32,Yo,0,n.work,{bits:5}),M0=!1}n.lencode=Ko,n.lenbits=9,n.distcode=Yo,n.distbits=5}function U0(n,e,t,a){var o,s=n.state;return s.window===null&&(s.wsize=1<<s.wbits,s.wnext=0,s.whave=0,s.window=new Kt.Buf8(s.wsize)),a>=s.wsize?(Kt.arraySet(s.window,e,t-s.wsize,s.wsize,0),s.wnext=0,s.whave=s.wsize):(o=s.wsize-s.wnext,o>a&&(o=a),Kt.arraySet(s.window,e,t-a,o,s.wnext),a-=o,a?(Kt.arraySet(s.window,e,t-a,a,0),s.wnext=a,s.whave=s.wsize):(s.wnext+=o,s.wnext===s.wsize&&(s.wnext=0),s.whave<s.wsize&&(s.whave+=o))),0}function Fv(n,e){var t,a,o,s,f,h,_,d,c,D,x,m,B,F,I=0,k,U,$,S,L,W,N,q,H=new Kt.Buf8(4),Z,Y,re=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15];if(!n||!n.state||!n.output||!n.input&&n.avail_in!==0)return fn;t=n.state,t.mode===hr&&(t.mode=Vo),f=n.next_out,o=n.output,_=n.avail_out,s=n.next_in,a=n.input,h=n.avail_in,d=t.hold,c=t.bits,D=h,x=_,q=li;e:for(;;)switch(t.mode){case h0:if(t.wrap===0){t.mode=Vo;break}for(;c<16;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if(t.wrap&2&&d===35615){t.check=0,H[0]=d&255,H[1]=d>>>8&255,t.check=Jn(t.check,H,2,0),d=0,c=0,t.mode=c0;break}if(t.flags=0,t.head&&(t.head.done=!1),!(t.wrap&1)||(((d&255)<<8)+(d>>8))%31){n.msg="incorrect header check",t.mode=Ye;break}if((d&15)!==l0){n.msg="unknown compression method",t.mode=Ye;break}if(d>>>=4,c-=4,N=(d&15)+8,t.wbits===0)t.wbits=N;else if(N>t.wbits){n.msg="invalid window size",t.mode=Ye;break}t.dmax=1<<N,n.adler=t.check=1,t.mode=d&512?m0:hr,d=0,c=0;break;case c0:for(;c<16;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if(t.flags=d,(t.flags&255)!==l0){n.msg="unknown compression method",t.mode=Ye;break}if(t.flags&57344){n.msg="unknown header flags set",t.mode=Ye;break}t.head&&(t.head.text=d>>8&1),t.flags&512&&(H[0]=d&255,H[1]=d>>>8&255,t.check=Jn(t.check,H,2,0)),d=0,c=0,t.mode=d0;case d0:for(;c<32;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}t.head&&(t.head.time=d),t.flags&512&&(H[0]=d&255,H[1]=d>>>8&255,H[2]=d>>>16&255,H[3]=d>>>24&255,t.check=Jn(t.check,H,4,0)),d=0,c=0,t.mode=p0;case p0:for(;c<16;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}t.head&&(t.head.xflags=d&255,t.head.os=d>>8),t.flags&512&&(H[0]=d&255,H[1]=d>>>8&255,t.check=Jn(t.check,H,2,0)),d=0,c=0,t.mode=g0;case g0:if(t.flags&1024){for(;c<16;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}t.length=d,t.head&&(t.head.extra_len=d),t.flags&512&&(H[0]=d&255,H[1]=d>>>8&255,t.check=Jn(t.check,H,2,0)),d=0,c=0}else t.head&&(t.head.extra=null);t.mode=_0;case _0:if(t.flags&1024&&(m=t.length,m>h&&(m=h),m&&(t.head&&(N=t.head.extra_len-t.length,t.head.extra||(t.head.extra=new Array(t.head.extra_len)),Kt.arraySet(t.head.extra,a,s,m,N)),t.flags&512&&(t.check=Jn(t.check,a,m,s)),h-=m,s+=m,t.length-=m),t.length))break e;t.length=0,t.mode=v0;case v0:if(t.flags&2048){if(h===0)break e;m=0;do N=a[s+m++],t.head&&N&&t.length<65536&&(t.head.name+=String.fromCharCode(N));while(N&&m<h);if(t.flags&512&&(t.check=Jn(t.check,a,m,s)),h-=m,s+=m,N)break e}else t.head&&(t.head.name=null);t.length=0,t.mode=w0;case w0:if(t.flags&4096){if(h===0)break e;m=0;do N=a[s+m++],t.head&&N&&t.length<65536&&(t.head.comment+=String.fromCharCode(N));while(N&&m<h);if(t.flags&512&&(t.check=Jn(t.check,a,m,s)),h-=m,s+=m,N)break e}else t.head&&(t.head.comment=null);t.mode=b0;case b0:if(t.flags&512){for(;c<16;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if(d!==(t.check&65535)){n.msg="header crc mismatch",t.mode=Ye;break}d=0,c=0}t.head&&(t.head.hcrc=t.flags>>9&1,t.head.done=!0),n.adler=t.check=0,t.mode=hr;break;case m0:for(;c<32;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}n.adler=t.check=N0(d),d=0,c=0,t.mode=Ou;case Ou:if(t.havedict===0)return n.next_out=f,n.avail_out=_,n.next_in=s,n.avail_in=h,t.hold=d,t.bits=c,vv;n.adler=t.check=1,t.mode=hr;case hr:if(e===gv||e===Lu)break e;case Vo:if(t.last){d>>>=c&7,c-=c&7,t.mode=Xo;break}for(;c<3;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}switch(t.last=d&1,d>>>=1,c-=1,d&3){case 0:t.mode=D0;break;case 1:if(Av(t),t.mode=Pu,e===Lu){d>>>=2,c-=2;break e}break;case 2:t.mode=x0;break;case 3:n.msg="invalid block type",t.mode=Ye}d>>>=2,c-=2;break;case D0:for(d>>>=c&7,c-=c&7;c<32;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if((d&65535)!==(d>>>16^65535)){n.msg="invalid stored block lengths",t.mode=Ye;break}if(t.length=d&65535,d=0,c=0,t.mode=Zo,e===Lu)break e;case Zo:t.mode=y0;case y0:if(m=t.length,m){if(m>h&&(m=h),m>_&&(m=_),m===0)break e;Kt.arraySet(o,a,s,m,f),h-=m,s+=m,_-=m,f+=m,t.length-=m;break}t.mode=hr;break;case x0:for(;c<14;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if(t.nlen=(d&31)+257,d>>>=5,c-=5,t.ndist=(d&31)+1,d>>>=5,c-=5,t.ncode=(d&15)+4,d>>>=4,c-=4,t.nlen>286||t.ndist>30){n.msg="too many length or distance symbols",t.mode=Ye;break}t.have=0,t.mode=E0;case E0:for(;t.have<t.ncode;){for(;c<3;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}t.lens[re[t.have++]]=d&7,d>>>=3,c-=3}for(;t.have<19;)t.lens[re[t.have++]]=0;if(t.lencode=t.lendyn,t.lenbits=7,Z={bits:t.lenbits},q=Ga(pv,t.lens,0,19,t.lencode,0,t.work,Z),t.lenbits=Z.bits,q){n.msg="invalid code lengths set",t.mode=Ye;break}t.have=0,t.mode=C0;case C0:for(;t.have<t.nlen+t.ndist;){for(;I=t.lencode[d&(1<<t.lenbits)-1],k=I>>>24,U=I>>>16&255,$=I&65535,!(k<=c);){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if($<16)d>>>=k,c-=k,t.lens[t.have++]=$;else{if($===16){for(Y=k+2;c<Y;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if(d>>>=k,c-=k,t.have===0){n.msg="invalid bit length repeat",t.mode=Ye;break}N=t.lens[t.have-1],m=3+(d&3),d>>>=2,c-=2}else if($===17){for(Y=k+3;c<Y;){if(h===0)break 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t&&!a?-1:!t&&a?1:this.unsigned?e.high>>>0>this.high>>>0||e.high===this.high&&e.low>>>0>this.low>>>0?-1:1:this.sub(e).isNegative()?-1:1},te.comp=te.compare,te.negate=function(){return!this.unsigned&&this.eq(Wt)?Wt:this.not().add(Zi)},te.neg=te.negate,te.add=function(e){Ut(e)||(e=Nn(e));var t=this.high>>>16,a=this.high&65535,o=this.low>>>16,s=this.low&65535,f=e.high>>>16,h=e.high&65535,_=e.low>>>16,d=e.low&65535,c=0,D=0,x=0,m=0;return m+=s+d,x+=m>>>16,m&=65535,x+=o+_,D+=x>>>16,x&=65535,D+=a+h,c+=D>>>16,D&=65535,c+=t+f,c&=65535,Ge(x<<16|m,c<<16|D,this.unsigned)},te.subtract=function(e){return Ut(e)||(e=Nn(e)),this.add(e.neg())},te.sub=te.subtract,te.multiply=function(e){if(this.isZero())return cn;if(Ut(e)||(e=Nn(e)),ln){var t=ln.mul(this.low,this.high,e.low,e.high);return Ge(t,ln.get_high(),this.unsigned)}if(e.isZero())return cn;if(this.eq(Wt))return e.isOdd()?Wt:cn;if(e.eq(Wt))return this.isOdd()?Wt:cn;if(this.isNegative())return e.isNegative()?this.neg().mul(e.neg()):this.neg().mul(e).neg();if(e.isNegative())return this.mul(e.neg()).neg();if(this.lt(Y0)&&e.lt(Y0))return hn(this.toNumber()*e.toNumber(),this.unsigned);var a=this.high>>>16,o=this.high&65535,s=this.low>>>16,f=this.low&65535,h=e.high>>>16,_=e.high&65535,d=e.low>>>16,c=e.low&65535,D=0,x=0,m=0,B=0;return B+=f*c,m+=B>>>16,B&=65535,m+=s*c,x+=m>>>16,m&=65535,m+=f*d,x+=m>>>16,m&=65535,x+=o*c,D+=x>>>16,x&=65535,x+=s*d,D+=x>>>16,x&=65535,x+=f*_,D+=x>>>16,x&=65535,D+=a*c+o*d+s*_+f*h,D&=65535,Ge(m<<16|B,D<<16|x,this.unsigned)},te.mul=te.multiply,te.divide=function(e){if(Ut(e)||(e=Nn(e)),e.isZero())throw Error("division by zero");if(ln){if(!this.unsigned&&this.high===-2147483648&&e.low===-1&&e.high===-1)return this;var t=(this.unsigned?ln.div_u:ln.div_s)(this.low,this.high,e.low,e.high);return Ge(t,ln.get_high(),this.unsigned)}if(this.isZero())return this.unsigned?di:cn;var a,o,s;if(this.unsigned){if(e.unsigned||(e=e.toUnsigned()),e.gt(this))return di;if(e.gt(this.shru(1)))return Q0;s=di}else{if(this.eq(Wt)){if(e.eq(Zi)||e.eq(ef))return Wt;if(e.eq(Wt))return Zi;var f=this.shr(1);return a=f.div(e).shl(1),a.eq(cn)?e.isNegative()?Zi:ef:(o=this.sub(e.mul(a)),s=a.add(o.div(e)),s)}else if(e.eq(Wt))return this.unsigned?di:cn;if(this.isNegative())return e.isNegative()?this.neg().div(e.neg()):this.neg().div(e).neg();if(e.isNegative())return this.div(e.neg()).neg();s=cn}for(o=this;o.gte(e);){a=Math.max(1,Math.floor(o.toNumber()/e.toNumber()));for(var h=Math.ceil(Math.log(a)/Math.LN2),_=h<=48?1:Gu(2,h-48),d=hn(a),c=d.mul(e);c.isNegative()||c.gt(o);)a-=_,d=hn(a,this.unsigned),c=d.mul(e);d.isZero()&&(d=Zi),s=s.add(d),o=o.sub(c)}return s},te.div=te.divide,te.modulo=function(e){if(Ut(e)||(e=Nn(e)),ln){var t=(this.unsigned?ln.rem_u:ln.rem_s)(this.low,this.high,e.low,e.high);return Ge(t,ln.get_high(),this.unsigned)}return this.sub(this.div(e).mul(e))},te.mod=te.modulo,te.rem=te.modulo,te.not=function(){return Ge(~this.low,~this.high,this.unsigned)},te.and=function(e){return Ut(e)||(e=Nn(e)),Ge(this.low&e.low,this.high&e.high,this.unsigned)},te.or=function(e){return Ut(e)||(e=Nn(e)),Ge(this.low|e.low,this.high|e.high,this.unsigned)},te.xor=function(e){return Ut(e)||(e=Nn(e)),Ge(this.low^e.low,this.high^e.high,this.unsigned)},te.shiftLeft=function(e){return Ut(e)&&(e=e.toInt()),(e&=63)===0?this:e<32?Ge(this.low<<e,this.high<<e|this.low>>>32-e,this.unsigned):Ge(0,this.low<<e-32,this.unsigned)},te.shl=te.shiftLeft,te.shiftRight=function(e){return Ut(e)&&(e=e.toInt()),(e&=63)===0?this:e<32?Ge(this.low>>>e|this.high<<32-e,this.high>>e,this.unsigned):Ge(this.high>>e-32,this.high>=0?0:-1,this.unsigned)},te.shr=te.shiftRight,te.shiftRightUnsigned=function(e){if(Ut(e)&&(e=e.toInt()),e&=63,e===0)return this;var t=this.high;if(e<32){var a=this.low;return Ge(a>>>e|t<<32-e,t>>>e,this.unsigned)}else return e===32?Ge(t,0,this.unsigned):Ge(t>>>e-32,0,this.unsigned)},te.shru=te.shiftRightUnsigned,te.shr_u=te.shiftRightUnsigned,te.toSigned=function(){return this.unsigned?Ge(this.low,this.high,!1):this},te.toUnsigned=function(){return this.unsigned?this:Ge(this.low,this.high,!0)},te.toBytes=function(e){return e?this.toBytesLE():this.toBytesBE()},te.toBytesLE=function(){var e=this.high,t=this.low;return[t&255,t>>>8&255,t>>>16&255,t>>>24,e&255,e>>>8&255,e>>>16&255,e>>>24]},te.toBytesBE=function(){var e=this.high,t=this.low;return[e>>>24,e>>>16&255,e>>>8&255,e&255,t>>>24,t>>>16&255,t>>>8&255,t&255]},We.fromBytes=function(e,t,a){return a?We.fromBytesLE(e,t):We.fromBytesBE(e,t)},We.fromBytesLE=function(e,t){return new We(e[0]|e[1]<<8|e[2]<<16|e[3]<<24,e[4]|e[5]<<8|e[6]<<16|e[7]<<24,t)},We.fromBytesBE=function(e,t){return new We(e[4]<<24|e[5]<<16|e[6]<<8|e[7],e[0]<<24|e[1]<<16|e[2]<<8|e[3],t)};var z0=wu(Wv);function ec(n){if(n.greaterThan(Number.MAX_SAFE_INTEGER)||n.lessThan(Number.MIN_SAFE_INTEGER))throw new Error("integer overflow");return n.toNumber()}let qv=class extends Error{};function Ha(n){if(n&&n.aborted){if(typeof DOMException<"u")throw new DOMException("aborted","AbortError");{const e=new qv("aborted");throw e.code="ERR_ABORTED",e}}}function Hv(n,e){return e.minv.blockPosition-n.maxv.blockPosition<65e3&&e.maxv.blockPosition-n.minv.blockPosition<5e6}function tc(n,e){const t=[];let a=null;return n.length===0?n:(n.sort(function(o,s){const f=o.minv.blockPosition-s.minv.blockPosition;return f!==0?f:o.minv.dataPosition-s.minv.dataPosition}),n.forEach(o=>{(!e||o.maxv.compareTo(e)>0)&&(a===null?(t.push(o),a=o):Hv(a,o)?o.maxv.compareTo(a.maxv)>0&&(a.maxv=o.maxv):(t.push(o),a=o))}),t)}class tf{constructor(e,t){this.blockPosition=e,this.dataPosition=t}toString(){return`${this.blockPosition}:${this.dataPosition}`}compareTo(e){return this.blockPosition-e.blockPosition||this.dataPosition-e.dataPosition}}function Xi(n,e=0,t=!1){if(t)throw new Error("big-endian virtual file offsets not implemented");return new tf(n[e+7]*1099511627776+n[e+6]*4294967296+n[e+5]*16777216+n[e+4]*65536+n[e+3]*256+n[e+2],n[e+1]<<8|n[e])}class qu{constructor(e,t,a,o=void 0){this.minv=e,this.maxv=t,this.bin=a,this._fetchedSize=o}toUniqueString(){return`${this.minv}..${this.maxv} (bin ${this.bin}, fetchedSize ${this.fetchedSize()})`}toString(){return this.toUniqueString()}compareTo(e){return this.minv.compareTo(e.minv)||this.maxv.compareTo(e.maxv)||this.bin-e.bin}fetchedSize(){return this._fetchedSize!==void 0?this._fetchedSize:this.maxv.blockPosition+65536-this.minv.blockPosition}}class nc{constructor({filehandle:e,renameRefSeqs:t=a=>a}){this.filehandle=e,this.renameRefSeq=t}async getMetadata(e={}){const{indices:t,...a}=await this.parse(e);return a}_findFirstData(e,t){return e?e.compareTo(t)>0?t:e:t}async parse(e={}){return this.parseP||(this.parseP=this._parse(e).catch(t=>{throw this.parseP=void 0,t})),this.parseP}async hasRefSeq(e,t={}){var a;return!!(!((a=(await this.parse(t)).indices[e])===null||a===void 0)&&a.binIndex)}}const Vv=21578324,rc=14;function Zv(n,e){return n+=1,e-=1,[[0,0],[1+(n>>26),1+(e>>26)],[9+(n>>23),9+(e>>23)],[73+(n>>20),73+(e>>20)],[585+(n>>17),585+(e>>17)],[4681+(n>>14),4681+(e>>14)]]}class Va extends nc{async lineCount(e,t={}){const a=await this.parse(t),o=a.refNameToId[e];if(o===void 0||!a.indices[o])return-1;const{stats:f}=a.indices[o];return f?f.lineCount:-1}async _parse(e={}){const t=await this.filehandle.readFile(e),a=await jo(t);if(Ha(e.signal),a.readUInt32LE(0)!==Vv)throw new Error("Not a TBI file");const o=a.readInt32LE(4),s=a.readInt32LE(8),f=s&65536?"zero-based-half-open":"1-based-closed",_={0:"generic",1:"SAM",2:"VCF"}[s&15];if(!_)throw new Error(`invalid Tabix preset format flags ${s}`);const d={ref:a.readInt32LE(12),start:a.readInt32LE(16),end:a.readInt32LE(20)},c=a.readInt32LE(24),D=5,x=((1<<(D+1)*3)-1)/7,m=2**(14+D*3),B=c?String.fromCharCode(c):null,F=a.readInt32LE(28),I=a.readInt32LE(32),{refNameToId:k,refIdToName:U}=this._parseNameBytes(a.slice(36,36+I));let $=36+I,S;return{indices:new Array(o).fill(0).map(()=>{const W=a.readInt32LE($);$+=4;const N={};let q;for(let Y=0;Y<W;Y+=1){const re=a.readUInt32LE($);if($+=4,re>x+1)throw new Error("tabix index contains too many bins, please use a CSI index");if(re===x+1){const se=a.readInt32LE($);$+=4,se===2&&(q=this.parsePseudoBin(a,$)),$+=16*se}else{const se=a.readInt32LE($);$+=4;const fe=new Array(se);for(let ce=0;ce<se;ce+=1){const Me=Xi(a,$),Fe=Xi(a,$+8);$+=16,S=this._findFirstData(S,Me),fe[ce]=new qu(Me,Fe,re)}N[re]=fe}}const H=a.readInt32LE($);$+=4;const Z=new Array(H);for(let Y=0;Y<H;Y+=1)Z[Y]=Xi(a,$),$+=8,S=this._findFirstData(S,Z[Y]);return{binIndex:N,linearIndex:Z,stats:q}}),metaChar:B,maxBinNumber:x,maxRefLength:m,skipLines:F,firstDataLine:S,columnNumbers:d,coordinateType:f,format:_,refIdToName:U,refNameToId:k,maxBlockSize:65536}}parsePseudoBin(e,t){return{lineCount:ec(z0.fromBytesLE(e.slice(t+16,t+24),!0))}}_parseNameBytes(e){let t=0,a=0;const o=[],s={};for(let f=0;f<e.length;f+=1)if(!e[f]){if(a<f){let h=e.toString("utf8",a,f);h=this.renameRefSeq(h),o[t]=h,s[h]=t}a=f+1,t+=1}return{refNameToId:s,refIdToName:o}}async blocksForRange(e,t,a,o={}){t<0&&(t=0);const s=await this.parse(o),f=s.refNameToId[e];if(f===void 0)return[];const h=s.indices[f];if(!h)return[];(h.linearIndex.length?h.linearIndex[t>>rc>=h.linearIndex.length?h.linearIndex.length-1:t>>rc]:new tf(0,0))||console.warn("querying outside of possible tabix range");const d=Zv(t,a),c=[];for(const[F,I]of d)for(let k=F;k<=I;k++)if(h.binIndex[k])for(const U of h.binIndex[k])c.push(new qu(U.minv,U.maxv,k));const D=h.linearIndex.length;let x=null;const m=Math.min(t>>14,D-1),B=Math.min(a>>14,D-1);for(let F=m;F<=B;++F){const I=h.linearIndex[F];I&&(!x||I.compareTo(x)<0)&&(x=I)}return tc(c,x)}}const Xv=21582659,Kv=38359875;function Yv(n,e){return n*2**e}function ic(n,e){return Math.floor(n/2**e)}class nf extends nc{constructor(e){super(e),this.maxBinNumber=0,this.depth=0,this.minShift=0}async lineCount(e,t={}){const a=await this.parse(t),o=a.refNameToId[e];if(o===void 0||!a.indices[o])return-1;const{stats:f}=a.indices[o];return f?f.lineCount:-1}indexCov(){throw new Error("CSI indexes do not support indexcov")}parseAuxData(e,t){const a=e.readInt32LE(t),o=a&65536?"zero-based-half-open":"1-based-closed",s={0:"generic",1:"SAM",2:"VCF"}[a&15];if(!s)throw new Error(`invalid Tabix preset format flags ${a}`);const f={ref:e.readInt32LE(t+4),start:e.readInt32LE(t+8),end:e.readInt32LE(t+12)},h=e.readInt32LE(t+16),_=h?String.fromCharCode(h):null,d=e.readInt32LE(t+20),c=e.readInt32LE(t+24),{refIdToName:D,refNameToId:x}=this._parseNameBytes(e.slice(t+28,t+28+c));return{refIdToName:D,refNameToId:x,skipLines:d,metaChar:_,columnNumbers:f,format:s,coordinateType:o}}_parseNameBytes(e){let t=0,a=0;const o=[],s={};for(let f=0;f<e.length;f+=1)if(!e[f]){if(a<f){let h=e.toString("utf8",a,f);h=this.renameRefSeq(h),o[t]=h,s[h]=t}a=f+1,t+=1}return{refNameToId:s,refIdToName:o}}async _parse(e={}){const t=await jo(await this.filehandle.readFile(e));let a;if(t.readUInt32LE(0)===Xv)a=1;else if(t.readUInt32LE(0)===Kv)a=2;else throw new Error("Not a CSI file");this.minShift=t.readInt32LE(4),this.depth=t.readInt32LE(8),this.maxBinNumber=((1<<(this.depth+1)*3)-1)/7;const o=2**(this.minShift+this.depth*3),s=t.readInt32LE(12),f=s&&s>=30?this.parseAuxData(t,16):{refIdToName:[],refNameToId:{},metaChar:null,columnNumbers:{ref:0,start:1,end:2},coordinateType:"zero-based-half-open",format:"generic"},h=t.readInt32LE(16+s);let _,d=16+s+4;const c=new Array(h).fill(0).map(()=>{const D=t.readInt32LE(d);d+=4;const x={};let m;for(let B=0;B<D;B+=1){const F=t.readUInt32LE(d);if(F>this.maxBinNumber)m=this.parsePseudoBin(t,d+4),d+=48;else{const I=Xi(t,d+4);_=this._findFirstData(_,I);const k=t.readInt32LE(d+12);d+=16;const U=new Array(k);for(let $=0;$<k;$+=1){const S=Xi(t,d),L=Xi(t,d+8);d+=16,U[$]=new qu(S,L,F)}x[F]=U}}return{binIndex:x,stats:m}});return{...f,csi:!0,refCount:h,maxBlockSize:65536,firstDataLine:_,csiVersion:a,indices:c,depth:this.depth,maxBinNumber:this.maxBinNumber,maxRefLength:o}}parsePseudoBin(e,t){return{lineCount:ec(z0.fromBytesLE(e.slice(t+28,t+36),!0))}}async blocksForRange(e,t,a,o={}){t<0&&(t=0);const s=await this.parse(o),f=s.refNameToId[e];if(f===void 0)return[];const h=s.indices[f];if(!h)return[];const _=this.reg2bins(t,a),d=[];for(const[c,D]of _)for(let x=c;x<=D;x++)if(h.binIndex[x])for(const m of h.binIndex[x])d.push(new qu(m.minv,m.maxv,x));return tc(d,new tf(0,0))}reg2bins(e,t){e-=1,e<1&&(e=1),t>2**50&&(t=2**34),t-=1;let a=0,o=0,s=this.minShift+this.depth*3;const f=[];for(;a<=this.depth;s-=3,o+=Yv(1,a*3),a+=1){const h=o+ic(e,s),_=o+ic(t,s);if(_-h+f.length>this.maxBinNumber)throw new Error(`query ${e}-${t} is too large for current binning scheme (shift ${this.minShift}, depth ${this.depth}), try a smaller query or a coarser index binning scheme`);f.push([h,_])}return f}}function Qv(n){return/^[\u0000-\u007F]*$/.test(n)}const Ki=typeof TextDecoder<"u"?new TextDecoder("utf8"):void 0;class ac{constructor({path:e,filehandle:t,url:a,tbiPath:o,tbiUrl:s,tbiFilehandle:f,csiPath:h,csiUrl:_,csiFilehandle:d,renameRefSeqs:c=x=>x,chunkCacheSize:D=5*2**20}){if(t)this.filehandle=t;else if(e)this.filehandle=new Fa(e);else if(a)this.filehandle=new Zn(a);else throw new TypeError("must provide either filehandle or path");if(f)this.index=new Va({filehandle:f,renameRefSeqs:c});else if(d)this.index=new nf({filehandle:d,renameRefSeqs:c});else if(o)this.index=new Va({filehandle:new Fa(o),renameRefSeqs:c});else if(h)this.index=new nf({filehandle:new Fa(h),renameRefSeqs:c});else if(e)this.index=new Va({filehandle:new Fa(`${e}.tbi`),renameRefSeqs:c});else if(_)this.index=new nf({filehandle:new Zn(_)});else if(s)this.index=new Va({filehandle:new Zn(s)});else if(a)this.index=new Va({filehandle:new Zn(`${a}.tbi`)});else throw new TypeError("must provide one of tbiFilehandle, tbiPath, csiFilehandle, csiPath, tbiUrl, csiUrl");this.renameRefSeq=c,this.chunkCache=new Aa({cache:new fh({maxSize:Math.floor(D/65536)}),fill:(x,m)=>this.readChunk(x,{signal:m})})}async getLines(e,t,a,o){var s,f;let h,_={},d;typeof o=="function"?d=o:(_=o,d=o.lineCallback,h=o.signal);const c=await this.index.getMetadata(_);Ha(h);const D=t??0,x=a??c.maxRefLength;if(!(D<=x))throw new TypeError("invalid start and end coordinates. start must be less than or equal to end");if(D===x)return;const m=await this.index.blocksForRange(e,D,x,_);Ha(h);for(const B of m){const{buffer:F,cpositions:I,dpositions:k}=await this.chunkCache.get(B.toString(),B,h);Ha(h);let U=0,$=0;const S=(s=Ki==null?void 0:Ki.decode(F))!==null&&s!==void 0?s:F.toString(),L=F.length<5e8&&Qv(S);for(;U<S.length;){let W,N;if(L){if(N=S.indexOf(`
-`,U),N===-1)break;W=S.slice(U,N)}else{if(N=F.indexOf(`
-`,U),N===-1)break;const Z=F.slice(U,N);W=(f=Ki==null?void 0:Ki.decode(Z))!==null&&f!==void 0?f:Z.toString()}if(k){for(;U+B.minv.dataPosition>=k[$++];);$--}const{startCoordinate:q,overlaps:H}=this.checkLine(c,e,D,x,W);if(H)d(W,I[$]*256+(U-k[$])+B.minv.dataPosition+1);else if(q!==void 0&&q>=x)return;U=N+1}}}async getMetadata(e={}){return this.index.getMetadata(e)}async getHeaderBuffer(e={}){const{firstDataLine:t,metaChar:a,maxBlockSize:o}=await this.getMetadata(e);Ha(e.signal);const s=((t==null?void 0:t.blockPosition)||0)+o,f=await this._readRegion(0,s,e),h=await jo(f);if(a){let _=-1;const d=10,c=a.charCodeAt(0);for(let D=0;D<h.length&&!(D===_+1&&h[D]!==c);D+=1)h[D]===d&&(_=D);return h.subarray(0,_+1)}return h}async getHeader(e={}){return(await this.getHeaderBuffer(e)).toString("utf8")}async getReferenceSequenceNames(e={}){return(await this.getMetadata(e)).refIdToName}checkLine(e,t,a,o,s){const{columnNumbers:f,metaChar:h,coordinateType:_,format:d}=e;if(h&&s.startsWith(h))return{overlaps:!1};let{ref:c,start:D,end:x}=f;c||(c=0),D||(D=0),x||(x=0),d==="VCF"&&(x=8);const m=Math.max(c,D,x);let B=1,F=0,I="",k=-1/0;const U=s.length;for(let $=0;$<U+1;$++)if(s[$]==="	"||$===U){if(B===c){if(this.renameRefSeq(s.slice(F,$))!==t)return{overlaps:!1}}else if(B===D){if(k=parseInt(s.slice(F,$),10),_==="1-based-closed"&&(k-=1),k>=o)return{startCoordinate:k,overlaps:!1};if((x===0||x===D)&&k+1<=a)return{startCoordinate:k,overlaps:!1}}else if(d==="VCF"&&B===4)I=s.slice(F,$);else if(B===x&&(d==="VCF"?this._getVcfEnd(k,I,s.slice(F,$)):Number.parseInt(s.slice(F,$),10))<=a)return{overlaps:!1};if(F=$+1,B+=1,B>m)break}return{startCoordinate:k,overlaps:!0}}_getVcfEnd(e,t,a){let o=e+t.length;const s=a.includes("SVTYPE=TRA");if(a[0]!=="."&&!s){let f=";";for(let h=0;h<a.length;h+=1){if(f===";"&&a.slice(h,h+4)==="END="){let _=a.indexOf(";",h);_===-1&&(_=a.length),o=parseInt(a.slice(h+4,_),10);break}f=a[h]}}else if(s)return e+1;return o}async lineCount(e,t={}){return this.index.lineCount(e,t)}async _readRegion(e,t,a={}){const o=Tn.alloc(t),{bytesRead:s,buffer:f}=await this.filehandle.read(o,0,t,e,a);return f.subarray(0,s)}async readChunk(e,t={}){const a=await this._readRegion(e.minv.blockPosition,e.fetchedSize(),t);return Uv(a,e)}}class Jv{constructor(e,t=null,a=1e5){ue(this,"url");ue(this,"indexUrl");ue(this,"dataLimit");ue(this,"tabix");ue(this,"getData",async(e,t,a)=>{const o=e.map(f=>{let h=a&&a.ensemblStyle?f.chr.replace("chr",""):f.chr;return h==="M"&&(h="MT"),this.getDataForLocus(h,f.start,f.end)}),s=await Promise.all(o);return a&&a.ensemblStyle&&e.forEach((f,h)=>{s[h].forEach(_=>_.chr=f.chr)}),Xt.flatten(s)});ue(this,"getDataForLocus",async(e,t,a)=>{const o=[];await this.tabix.getLines(e,t,a,f=>o.push(f));let s;return o.length>this.dataLimit?s=F_(o,this.dataLimit):s=o,s.map(this._parseLine)});ue(this,"_parseLine",e=>{const t=e.split("	");if(t.length<3)return;let a={chr:t[0],start:Number.parseInt(t[1],10),end:Number.parseInt(t[2],10),n:t.length};for(let o=3;o<t.length;o++)a[o]=t[o];return a});this.url=e,this.indexUrl=t||e+".tbi",this.dataLimit=a,this.tabix=new ac({filehandle:new Zn(e,{fetch:bo}),tbiFilehandle:new Zn(this.indexUrl,{fetch:bo})})}}const Hu=BigInt(32);function jv(n,e,t){const a=+!!t,o=+!t;return BigInt(n.getInt32(e,t)*o+n.getInt32(e+4,t)*a)<<Hu|BigInt(n.getUint32(e,t)*a+n.getUint32(e+4,t)*o)}function zv(n,e,t){const a=n.getUint32(e,t),o=n.getUint32(e+4,t),s=+!!t,f=+!t;return BigInt(a*f+o*s)<<Hu|BigInt(a*s+o*f)}function ew(n,e,t,a){const o=Number(t>>Hu),s=Number(t&BigInt(4294967295));a?(n.setInt32(e+4,o,a),n.setUint32(e,s,a)):(n.setInt32(e,o,a),n.setUint32(e+4,s,a))}function tw(n,e,t,a){const o=Number(t>>Hu),s=Number(t&BigInt(4294967295));a?(n.setUint32(e+4,o,a),n.setUint32(e,s,a)):(n.setUint32(e,o,a),n.setUint32(e+4,s,a))}"getBigInt64"in DataView||(DataView.prototype.getBigInt64=function(n,e){return jv(this,n,e)}),"getBigUint64"in DataView||(DataView.prototype.getBigUint64=function(n,e){return zv(this,n,e)}),"setBigInt64"in DataView||(DataView.prototype.setBigInt64=function(n,e,t){ew(this,n,e,t)}),"setBigUint64"in DataView||(DataView.prototype.setBigUint64=function(n,e,t){tw(this,n,e,t)});class nw{constructor(e,t){this.code="",this.scopes=[["vars"]],this.bitFields=[],this.tmpVariableCount=0,this.references=new Map,this.imports=[],this.reverseImports=new Map,this.useContextVariables=!1,this.importPath=e,this.useContextVariables=t}generateVariable(e){const t=[...this.scopes[this.scopes.length-1]];return e&&t.push(e),t.join(".")}generateOption(e){switch(typeof e){case"number":return e.toString();case"string":return this.generateVariable(e);case"function":return`${this.addImport(e)}.call(${this.generateVariable()}, vars)`}}generateError(e){this.pushCode(`throw new Error(${e});`)}generateTmpVariable(){return"$tmp"+this.tmpVariableCount++}pushCode(e){this.code+=e+`
-`}pushPath(e){e&&this.scopes[this.scopes.length-1].push(e)}popPath(e){e&&this.scopes[this.scopes.length-1].pop()}pushScope(e){this.scopes.push([e])}popScope(){this.scopes.pop()}addImport(e){if(!this.importPath)return`(${e})`;let t=this.reverseImports.get(e);return t||(t=this.imports.push(e)-1,this.reverseImports.set(e,t)),`${this.importPath}[${t}]`}addReference(e){this.references.has(e)||this.references.set(e,{resolved:!1,requested:!1})}markResolved(e){const t=this.references.get(e);t&&(t.resolved=!0)}markRequested(e){e.forEach(t=>{const a=this.references.get(t);a&&(a.requested=!0)})}getUnresolvedReferences(){return Array.from(this.references).filter(([e,t])=>!t.resolved&&!t.requested).map(([e,t])=>e)}}const $n=new Map,pi="___parser_",Ln={uint8:1,uint16le:2,uint16be:2,uint32le:4,uint32be:4,int8:1,int16le:2,int16be:2,int32le:4,int32be:4,int64be:8,int64le:8,uint64be:8,uint64le:8,floatle:4,floatbe:4,doublele:8,doublebe:8},Vu={uint8:"Uint8",uint16le:"Uint16",uint16be:"Uint16",uint32le:"Uint32",uint32be:"Uint32",int8:"Int8",int16le:"Int16",int16be:"Int16",int32le:"Int32",int32be:"Int32",int64be:"BigInt64",int64le:"BigInt64",uint64be:"BigUint64",uint64le:"BigUint64",floatle:"Float32",floatbe:"Float32",doublele:"Float64",doublebe:"Float64"},Zu={uint8:!1,uint16le:!0,uint16be:!1,uint32le:!0,uint32be:!1,int8:!1,int16le:!0,int16be:!1,int32le:!0,int32be:!1,int64be:!1,int64le:!0,uint64be:!1,uint64le:!0,floatle:!0,floatbe:!1,doublele:!0,doublebe:!1};class Ie{constructor(){this.varName="",this.type="",this.options={},this.endian="be",this.useContextVariables=!1}static start(){return new Ie}primitiveGenerateN(e,t){const a=Vu[e],o=Zu[e];t.pushCode(`${t.generateVariable(this.varName)} = dataView.get${a}(offset, ${o});`),t.pushCode(`offset += ${Ln[e]};`)}primitiveN(e,t,a){return this.setNextParser(e,t,a)}useThisEndian(e){return e+this.endian.toLowerCase()}uint8(e,t={}){return this.primitiveN("uint8",e,t)}uint16(e,t={}){return this.primitiveN(this.useThisEndian("uint16"),e,t)}uint16le(e,t={}){return this.primitiveN("uint16le",e,t)}uint16be(e,t={}){return this.primitiveN("uint16be",e,t)}uint32(e,t={}){return this.primitiveN(this.useThisEndian("uint32"),e,t)}uint32le(e,t={}){return this.primitiveN("uint32le",e,t)}uint32be(e,t={}){return this.primitiveN("uint32be",e,t)}int8(e,t={}){return this.primitiveN("int8",e,t)}int16(e,t={}){return this.primitiveN(this.useThisEndian("int16"),e,t)}int16le(e,t={}){return this.primitiveN("int16le",e,t)}int16be(e,t={}){return this.primitiveN("int16be",e,t)}int32(e,t={}){return this.primitiveN(this.useThisEndian("int32"),e,t)}int32le(e,t={}){return this.primitiveN("int32le",e,t)}int32be(e,t={}){return this.primitiveN("int32be",e,t)}bigIntVersionCheck(){if(!DataView.prototype.getBigInt64)throw new Error("BigInt64 is unsupported on this runtime")}int64(e,t={}){return this.bigIntVersionCheck(),this.primitiveN(this.useThisEndian("int64"),e,t)}int64be(e,t={}){return this.bigIntVersionCheck(),this.primitiveN("int64be",e,t)}int64le(e,t={}){return this.bigIntVersionCheck(),this.primitiveN("int64le",e,t)}uint64(e,t={}){return this.bigIntVersionCheck(),this.primitiveN(this.useThisEndian("uint64"),e,t)}uint64be(e,t={}){return this.bigIntVersionCheck(),this.primitiveN("uint64be",e,t)}uint64le(e,t={}){return this.bigIntVersionCheck(),this.primitiveN("uint64le",e,t)}floatle(e,t={}){return this.primitiveN("floatle",e,t)}floatbe(e,t={}){return this.primitiveN("floatbe",e,t)}doublele(e,t={}){return this.primitiveN("doublele",e,t)}doublebe(e,t={}){return this.primitiveN("doublebe",e,t)}bitN(e,t,a){return a.length=e,this.setNextParser("bit",t,a)}bit1(e,t={}){return this.bitN(1,e,t)}bit2(e,t={}){return this.bitN(2,e,t)}bit3(e,t={}){return this.bitN(3,e,t)}bit4(e,t={}){return this.bitN(4,e,t)}bit5(e,t={}){return this.bitN(5,e,t)}bit6(e,t={}){return this.bitN(6,e,t)}bit7(e,t={}){return this.bitN(7,e,t)}bit8(e,t={}){return this.bitN(8,e,t)}bit9(e,t={}){return this.bitN(9,e,t)}bit10(e,t={}){return this.bitN(10,e,t)}bit11(e,t={}){return this.bitN(11,e,t)}bit12(e,t={}){return this.bitN(12,e,t)}bit13(e,t={}){return this.bitN(13,e,t)}bit14(e,t={}){return this.bitN(14,e,t)}bit15(e,t={}){return this.bitN(15,e,t)}bit16(e,t={}){return this.bitN(16,e,t)}bit17(e,t={}){return this.bitN(17,e,t)}bit18(e,t={}){return this.bitN(18,e,t)}bit19(e,t={}){return this.bitN(19,e,t)}bit20(e,t={}){return this.bitN(20,e,t)}bit21(e,t={}){return this.bitN(21,e,t)}bit22(e,t={}){return this.bitN(22,e,t)}bit23(e,t={}){return this.bitN(23,e,t)}bit24(e,t={}){return this.bitN(24,e,t)}bit25(e,t={}){return this.bitN(25,e,t)}bit26(e,t={}){return this.bitN(26,e,t)}bit27(e,t={}){return this.bitN(27,e,t)}bit28(e,t={}){return this.bitN(28,e,t)}bit29(e,t={}){return this.bitN(29,e,t)}bit30(e,t={}){return this.bitN(30,e,t)}bit31(e,t={}){return this.bitN(31,e,t)}bit32(e,t={}){return this.bitN(32,e,t)}namely(e){return $n.set(e,this),this.alias=e,this}skip(e,t={}){return this.seek(e,t)}seek(e,t={}){if(t.assert)throw new Error("assert option on seek is not allowed.");return this.setNextParser("seek","",{length:e})}string(e,t){if(!t.zeroTerminated&&!t.length&&!t.greedy)throw new Error("One of length, zeroTerminated, or greedy must be defined for string.");if((t.zeroTerminated||t.length)&&t.greedy)throw new Error("greedy is mutually exclusive with length and zeroTerminated for string.");if(t.stripNull&&!(t.length||t.greedy))throw new Error("length or greedy must be defined if stripNull is enabled.");return t.encoding=t.encoding||"utf8",this.setNextParser("string",e,t)}buffer(e,t){if(!t.length&&!t.readUntil)throw new Error("length or readUntil must be defined for buffer.");return this.setNextParser("buffer",e,t)}wrapped(e,t){if(typeof t!="object"&&typeof e=="object"&&(t=e,e=""),!t||!t.wrapper||!t.type)throw new Error("Both wrapper and type must be defined for wrapped.");if(!t.length&&!t.readUntil)throw new Error("length or readUntil must be defined for wrapped.");return this.setNextParser("wrapper",e,t)}array(e,t){if(!t.readUntil&&!t.length&&!t.lengthInBytes)throw new Error("One of readUntil, length and lengthInBytes must be defined for array.");if(!t.type)throw new Error("type is required for array.");if(typeof t.type=="string"&&!$n.has(t.type)&&!(t.type in Ln))throw new Error(`Array element type "${t.type}" is unkown.`);return this.setNextParser("array",e,t)}choice(e,t){if(typeof t!="object"&&typeof e=="object"&&(t=e,e=""),!t)throw new Error("tag and choices are are required for choice.");if(!t.tag)throw new Error("tag is requird for choice.");if(!t.choices)throw new Error("choices is required for choice.");for(const a in t.choices){const o=parseInt(a,10),s=t.choices[o];if(isNaN(o))throw new Error(`Choice key "${a}" is not a number.`);if(typeof s=="string"&&!$n.has(s)&&!(s in Ln))throw new Error(`Choice type "${s}" is unkown.`)}return this.setNextParser("choice",e,t)}nest(e,t){if(typeof t!="object"&&typeof e=="object"&&(t=e,e=""),!t||!t.type)throw new Error("type is required for nest.");if(!(t.type instanceof Ie)&&!$n.has(t.type))throw new Error("type must be a known parser name or a Parser object.");if(!(t.type instanceof Ie)&&!e)throw new Error("type must be a Parser object if the variable name is omitted.");return this.setNextParser("nest",e,t)}pointer(e,t){if(!t.offset)throw new Error("offset is required for pointer.");if(!t.type)throw new Error("type is required for pointer.");if(typeof t.type=="string"&&!(t.type in Ln)&&!$n.has(t.type))throw new Error(`Pointer type "${t.type}" is unkown.`);return this.setNextParser("pointer",e,t)}saveOffset(e,t={}){return this.setNextParser("saveOffset",e,t)}endianness(e){switch(e.toLowerCase()){case"little":this.endian="le";break;case"big":this.endian="be";break;default:throw new Error('endianness must be one of "little" or "big"')}return this}endianess(e){return this.endianness(e)}useContextVars(e=!0){return this.useContextVariables=e,this}create(e){if(!(e instanceof Function))throw new Error("Constructor must be a Function object.");return this.constructorFn=e,this}getContext(e){const t=new nw(e,this.useContextVariables);return t.pushCode("var dataView = new DataView(buffer.buffer, buffer.byteOffset, buffer.length);"),this.alias?(this.addAliasedCode(t),t.pushCode(`return ${pi+this.alias}(0).result;`)):this.addRawCode(t),t}getCode(){return this.getContext("imports").code}addRawCode(e){e.pushCode("var offset = 0;"),e.pushCode(`var vars = ${this.constructorFn?"new constructorFn()":"{}"};`),e.pushCode("vars.$parent = null;"),e.pushCode("vars.$root = vars;"),this.generate(e),this.resolveReferences(e),e.pushCode("delete vars.$parent;"),e.pushCode("delete vars.$root;"),e.pushCode("return vars;")}addAliasedCode(e){return e.pushCode(`function ${pi+this.alias}(offset, context) {`),e.pushCode(`var vars = ${this.constructorFn?"new constructorFn()":"{}"};`),e.pushCode("var ctx = Object.assign({$parent: null, $root: vars}, context || {});"),e.pushCode("vars = Object.assign(vars, ctx);"),this.generate(e),e.markResolved(this.alias),this.resolveReferences(e),e.pushCode("Object.keys(ctx).forEach(function (item) { delete vars[item]; });"),e.pushCode("return { offset: offset, result: vars };"),e.pushCode("}"),e}resolveReferences(e){const t=e.getUnresolvedReferences();e.markRequested(t),t.forEach(a=>{var o;(o=$n.get(a))===null||o===void 0||o.addAliasedCode(e)})}compile(){const e="imports",t=this.getContext(e);this.compiled=new Function(e,"TextDecoder",`return function (buffer, constructorFn) { ${t.code} };`)(t.imports,TextDecoder)}sizeOf(){let e=NaN;if(Object.keys(Ln).indexOf(this.type)>=0)e=Ln[this.type];else if(this.type==="string"&&typeof this.options.length=="number")e=this.options.length;else if(this.type==="buffer"&&typeof this.options.length=="number")e=this.options.length;else if(this.type==="array"&&typeof this.options.length=="number"){let t=NaN;typeof this.options.type=="string"?t=Ln[this.options.type]:this.options.type instanceof Ie&&(t=this.options.type.sizeOf()),e=this.options.length*t}else this.type==="seek"?e=this.options.length:this.type==="nest"?e=this.options.type.sizeOf():this.type||(e=0);return this.next&&(e+=this.next.sizeOf()),e}parse(e){return this.compiled||this.compile(),this.compiled(e,this.constructorFn)}setNextParser(e,t,a){const o=new Ie;return o.type=e,o.varName=t,o.options=a,o.endian=this.endian,this.head?this.head.next=o:this.next=o,this.head=o,this}generate(e){if(this.type){switch(this.type){case"uint8":case"uint16le":case"uint16be":case"uint32le":case"uint32be":case"int8":case"int16le":case"int16be":case"int32le":case"int32be":case"int64be":case"int64le":case"uint64be":case"uint64le":case"floatle":case"floatbe":case"doublele":case"doublebe":this.primitiveGenerateN(this.type,e);break;case"bit":this.generateBit(e);break;case"string":this.generateString(e);break;case"buffer":this.generateBuffer(e);break;case"seek":this.generateSeek(e);break;case"nest":this.generateNest(e);break;case"array":this.generateArray(e);break;case"choice":this.generateChoice(e);break;case"pointer":this.generatePointer(e);break;case"saveOffset":this.generateSaveOffset(e);break;case"wrapper":this.generateWrapper(e);break}this.type!=="bit"&&this.generateAssert(e)}const t=e.generateVariable(this.varName);return this.options.formatter&&this.type!=="bit"&&this.generateFormatter(e,t,this.options.formatter),this.generateNext(e)}generateAssert(e){if(!this.options.assert)return;const t=e.generateVariable(this.varName);switch(typeof this.options.assert){case"function":{const a=e.addImport(this.options.assert);e.pushCode(`if (!${a}.call(vars, ${t})) {`)}break;case"number":e.pushCode(`if (${this.options.assert} !== ${t}) {`);break;case"string":e.pushCode(`if (${JSON.stringify(this.options.assert)} !== ${t}) {`);break;default:throw new Error("assert option must be a string, number or a function.")}e.generateError(`"Assertion error: ${t} is " + ${JSON.stringify(this.options.assert.toString())}`),e.pushCode("}")}generateNext(e){return this.next&&(e=this.next.generate(e)),e}generateBit(e){const t=JSON.parse(JSON.stringify(this));if(t.options=this.options,t.generateAssert=this.generateAssert.bind(this),t.generateFormatter=this.generateFormatter.bind(this),t.varName=e.generateVariable(t.varName),e.bitFields.push(t),!this.next||this.next&&["bit","nest"].indexOf(this.next.type)<0){const a=e.generateTmpVariable();e.pushCode(`var ${a} = 0;`);const o=(c=0)=>{let D=0;for(let x=c;x<e.bitFields.length;x++){const m=e.bitFields[x].options.length;if(D+m>32)break;D+=m}return D},s=c=>(c<=8?(e.pushCode(`${a} = dataView.getUint8(offset);`),c=8):c<=16?(e.pushCode(`${a} = dataView.getUint16(offset);`),c=16):c<=24?(e.pushCode(`${a} = (dataView.getUint16(offset) << 8) | dataView.getUint8(offset + 2);`),c=24):(e.pushCode(`${a} = dataView.getUint32(offset);`),c=32),e.pushCode(`offset += ${c/8};`),c);let f=0;const h=this.endian==="be";let _=0,d=0;e.bitFields.forEach((c,D)=>{let x=c.options.length;if(x>d){if(d){const F=-1>>>32-d;e.pushCode(`${c.varName} = (${a} & 0x${F.toString(16)}) << 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t=e.generateVariable(this.varName);if(typeof this.options.readUntil=="function"){const a=this.options.readUntil,o=e.generateTmpVariable(),s=e.generateTmpVariable();e.pushCode(`var ${o} = offset;`),e.pushCode(`var ${s} = 0;`),e.pushCode("while (offset < buffer.length) {"),e.pushCode(`${s} = dataView.getUint8(offset);`);const f=e.addImport(a);e.pushCode(`if (${f}.call(${e.generateVariable()}, ${s}, buffer.subarray(offset))) break;`),e.pushCode("offset += 1;"),e.pushCode("}"),e.pushCode(`${t} = buffer.subarray(${o}, offset);`)}else if(this.options.readUntil==="eof")e.pushCode(`${t} = buffer.subarray(offset);`);else{const a=e.generateOption(this.options.length);e.pushCode(`${t} = buffer.subarray(offset, offset + ${a});`),e.pushCode(`offset += ${a};`)}this.options.clone&&e.pushCode(`${t} = buffer.constructor.from(${t});`)}generateArray(e){const t=e.generateOption(this.options.length),a=e.generateOption(this.options.lengthInBytes),o=this.options.type,s=e.generateTmpVariable(),f=e.generateVariable(this.varName),h=e.generateTmpVariable(),_=this.options.key,d=typeof _=="string";if(d?e.pushCode(`${f} = {};`):e.pushCode(`${f} = [];`),typeof this.options.readUntil=="function"?e.pushCode("do {"):this.options.readUntil==="eof"?e.pushCode(`for (var ${s} = 0; offset < buffer.length; ${s}++) {`):a!==void 0?e.pushCode(`for (var ${s} = offset + ${a}; offset < ${s}; ) {`):e.pushCode(`for (var ${s} = ${t}; ${s} > 0; ${s}--) {`),typeof o=="string")if($n.get(o)){const c=e.generateTmpVariable();if(e.pushCode(`var ${c} = ${pi+o}(offset, {`),e.useContextVariables){const D=e.generateVariable();e.pushCode(`$parent: ${D},`),e.pushCode(`$root: ${D}.$root,`),!this.options.readUntil&&a===void 0&&e.pushCode(`$index: ${t} - ${s},`)}e.pushCode("});"),e.pushCode(`var ${h} = ${c}.result; offset = ${c}.offset;`),o!==this.alias&&e.addReference(o)}else{const 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Z[s++]=x[N++];while(--S);N=s-W,q=Z}}}else if(N+=D-S,S<L){L-=S;do Z[s++]=x[N++];while(--S);N=s-W,q=Z}for(;L>2;)Z[s++]=q[N++],Z[s++]=q[N++],Z[s++]=q[N++],L-=3;L&&(Z[s++]=q[N++],L>1&&(Z[s++]=q[N++]))}else{N=s-W;do Z[s++]=Z[N++],Z[s++]=Z[N++],Z[s++]=Z[N++],L-=3;while(L>2);L&&(Z[s++]=Z[N++],L>1&&(Z[s++]=Z[N++]))}}else if(S&64){e.msg="invalid distance code",Y.mode=Xu;break e}else{$=I[($&65535)+(m&(1<<S)-1)];continue n}break}}else if(S&64)if(S&32){Y.mode=Ew;break e}else{e.msg="invalid literal/length code",Y.mode=Xu;break e}else{$=F[($&65535)+(m&(1<<S)-1)];continue t}break}}while(a<o&&s<h);L=B>>3,a-=L,B-=L<<3,m&=(1<<B)-1,e.next_in=a,e.next_out=s,e.avail_in=a<o?5+(o-a):5-(a-o),e.avail_out=s<h?257+(h-s):257-(s-h),Y.hold=m,Y.bits=B};const Qi=15,cc=852,dc=592,pc=0,sf=1,gc=2,Aw=new Uint16Array([3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0]),Fw=new Uint8Array([16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78]),Bw=new Uint16Array([1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0]),Sw=new Uint8Array([16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64]);var Xa=(n,e,t,a,o,s,f,h)=>{const _=h.bits;let d=0,c=0,D=0,x=0,m=0,B=0,F=0,I=0,k=0,U=0,$,S,L,W,N,q=null,H;const Z=new Uint16Array(Qi+1),Y=new Uint16Array(Qi+1);let re=null,se,fe,ce;for(d=0;d<=Qi;d++)Z[d]=0;for(c=0;c<a;c++)Z[e[t+c]]++;for(m=_,x=Qi;x>=1&&Z[x]===0;x--);if(m>x&&(m=x),x===0)return o[s++]=1<<24|64<<16|0,o[s++]=1<<24|64<<16|0,h.bits=1,0;for(D=1;D<x&&Z[D]===0;D++);for(m<D&&(m=D),I=1,d=1;d<=Qi;d++)if(I<<=1,I-=Z[d],I<0)return-1;if(I>0&&(n===pc||x!==1))return-1;for(Y[1]=0,d=1;d<Qi;d++)Y[d+1]=Y[d]+Z[d];for(c=0;c<a;c++)e[t+c]!==0&&(f[Y[e[t+c]]++]=c);if(n===pc?(q=re=f,H=20):n===sf?(q=Aw,re=Fw,H=257):(q=Bw,re=Sw,H=0),U=0,c=0,d=D,N=s,B=m,F=0,L=-1,k=1<<m,W=k-1,n===sf&&k>cc||n===gc&&k>dc)return 1;for(;;){se=d-F,f[c]+1<H?(fe=0,ce=f[c]):f[c]>=H?(fe=re[f[c]-H],ce=q[f[c]-H]):(fe=96,ce=0),$=1<<d-F,S=1<<B,D=S;do S-=$,o[N+(U>>F)+S]=se<<24|fe<<16|ce|0;while(S!==0);for($=1<<d-1;U&$;)$>>=1;if($!==0?(U&=$-1,U+=$):U=0,c++,--Z[d]===0){if(d===x)break;d=e[t+f[c]]}if(d>m&&(U&W)!==L){for(F===0&&(F=m),N+=D,B=d-F,I=1<<B;B+F<x&&(I-=Z[B+F],!(I<=0));)B++,I<<=1;if(k+=1<<B,n===sf&&k>cc||n===gc&&k>dc)return 1;L=U&W,o[L]=m<<24|B<<16|N-s|0}}return U!==0&&(o[N+U]=d-F<<24|64<<16|0),h.bits=m,0};const Iw=0,_c=1,vc=2,{Z_FINISH:wc,Z_BLOCK:Tw,Z_TREES:Ku,Z_OK:gi,Z_STREAM_END:kw,Z_NEED_DICT:Rw,Z_STREAM_ERROR:dn,Z_DATA_ERROR:bc,Z_MEM_ERROR:mc,Z_BUF_ERROR:Nw,Z_DEFLATED:Dc}=fc,Yu=16180,yc=16181,xc=16182,Ec=16183,Cc=16184,Ac=16185,Fc=16186,Bc=16187,Sc=16188,Ic=16189,Qu=16190,cr=16191,of=16192,Tc=16193,ff=16194,kc=16195,Rc=16196,Nc=16197,$c=16198,Ju=16199,ju=16200,Lc=16201,Oc=16202,Pc=16203,Mc=16204,Uc=16205,lf=16206,Wc=16207,Gc=16208,Qe=16209,qc=16210,Hc=16211,$w=852,Lw=592,Ow=15,Vc=n=>(n>>>24&255)+(n>>>8&65280)+((n&65280)<<8)+((n&255)<<24);function Pw(){this.strm=null,this.mode=0,this.last=!1,this.wrap=0,this.havedict=!1,this.flags=0,this.dmax=0,this.check=0,this.total=0,this.head=null,this.wbits=0,this.wsize=0,this.whave=0,this.wnext=0,this.window=null,this.hold=0,this.bits=0,this.length=0,this.offset=0,this.extra=0,this.lencode=null,this.distcode=null,this.lenbits=0,this.distbits=0,this.ncode=0,this.nlen=0,this.ndist=0,this.have=0,this.next=null,this.lens=new Uint16Array(320),this.work=new Uint16Array(288),this.lendyn=null,this.distdyn=null,this.sane=0,this.back=0,this.was=0}const _i=n=>{if(!n)return 1;const e=n.state;return!e||e.strm!==n||e.mode<Yu||e.mode>Hc?1:0},Zc=n=>{if(_i(n))return dn;const e=n.state;return n.total_in=n.total_out=e.total=0,n.msg="",e.wrap&&(n.adler=e.wrap&1),e.mode=Yu,e.last=0,e.havedict=0,e.flags=-1,e.dmax=32768,e.head=null,e.hold=0,e.bits=0,e.lencode=e.lendyn=new Int32Array($w),e.distcode=e.distdyn=new Int32Array(Lw),e.sane=1,e.back=-1,gi},Xc=n=>{if(_i(n))return dn;const e=n.state;return e.wsize=0,e.whave=0,e.wnext=0,Zc(n)},Kc=(n,e)=>{let t;if(_i(n))return dn;const a=n.state;return e<0?(t=0,e=-e):(t=(e>>4)+5,e<48&&(e&=15)),e&&(e<8||e>15)?dn:(a.window!==null&&a.wbits!==e&&(a.window=null),a.wrap=t,a.wbits=e,Xc(n))},Yc=(n,e)=>{if(!n)return dn;const t=new Pw;n.state=t,t.strm=n,t.window=null,t.mode=Yu;const a=Kc(n,e);return a!==gi&&(n.state=null),a},Mw=n=>Yc(n,Ow);let Qc=!0,hf,cf;const Uw=n=>{if(Qc){hf=new Int32Array(512),cf=new Int32Array(32);let e=0;for(;e<144;)n.lens[e++]=8;for(;e<256;)n.lens[e++]=9;for(;e<280;)n.lens[e++]=7;for(;e<288;)n.lens[e++]=8;for(Xa(_c,n.lens,0,288,hf,0,n.work,{bits:9}),e=0;e<32;)n.lens[e++]=5;Xa(vc,n.lens,0,32,cf,0,n.work,{bits:5}),Qc=!1}n.lencode=hf,n.lenbits=9,n.distcode=cf,n.distbits=5},Jc=(n,e,t,a)=>{let o;const s=n.state;return s.window===null&&(s.wsize=1<<s.wbits,s.wnext=0,s.whave=0,s.window=new Uint8Array(s.wsize)),a>=s.wsize?(s.window.set(e.subarray(t-s.wsize,t),0),s.wnext=0,s.whave=s.wsize):(o=s.wsize-s.wnext,o>a&&(o=a),s.window.set(e.subarray(t-a,t-a+o),s.wnext),a-=o,a?(s.window.set(e.subarray(t-a,t),0),s.wnext=a,s.whave=s.wsize):(s.wnext+=o,s.wnext===s.wsize&&(s.wnext=0),s.whave<s.wsize&&(s.whave+=o))),0},Ww=(n,e)=>{let t,a,o,s,f,h,_,d,c,D,x,m,B,F,I=0,k,U,$,S,L,W,N,q;const H=new Uint8Array(4);let Z,Y;const re=new Uint8Array([16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15]);if(_i(n)||!n.output||!n.input&&n.avail_in!==0)return dn;t=n.state,t.mode===cr&&(t.mode=of),f=n.next_out,o=n.output,_=n.avail_out,s=n.next_in,a=n.input,h=n.avail_in,d=t.hold,c=t.bits,D=h,x=_,q=gi;e:for(;;)switch(t.mode){case Yu:if(t.wrap===0){t.mode=of;break}for(;c<16;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if(t.wrap&2&&d===35615){t.wbits===0&&(t.wbits=15),t.check=0,H[0]=d&255,H[1]=d>>>8&255,t.check=jn(t.check,H,2,0),d=0,c=0,t.mode=yc;break}if(t.head&&(t.head.done=!1),!(t.wrap&1)||(((d&255)<<8)+(d>>8))%31){n.msg="incorrect header check",t.mode=Qe;break}if((d&15)!==Dc){n.msg="unknown compression method",t.mode=Qe;break}if(d>>>=4,c-=4,N=(d&15)+8,t.wbits===0&&(t.wbits=N),N>15||N>t.wbits){n.msg="invalid window size",t.mode=Qe;break}t.dmax=1<<t.wbits,t.flags=0,n.adler=t.check=1,t.mode=d&512?Ic:cr,d=0,c=0;break;case yc:for(;c<16;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if(t.flags=d,(t.flags&255)!==Dc){n.msg="unknown compression method",t.mode=Qe;break}if(t.flags&57344){n.msg="unknown header flags set",t.mode=Qe;break}t.head&&(t.head.text=d>>8&1),t.flags&512&&t.wrap&4&&(H[0]=d&255,H[1]=d>>>8&255,t.check=jn(t.check,H,2,0)),d=0,c=0,t.mode=xc;case xc:for(;c<32;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}t.head&&(t.head.time=d),t.flags&512&&t.wrap&4&&(H[0]=d&255,H[1]=d>>>8&255,H[2]=d>>>16&255,H[3]=d>>>24&255,t.check=jn(t.check,H,4,0)),d=0,c=0,t.mode=Ec;case Ec:for(;c<16;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}t.head&&(t.head.xflags=d&255,t.head.os=d>>8),t.flags&512&&t.wrap&4&&(H[0]=d&255,H[1]=d>>>8&255,t.check=jn(t.check,H,2,0)),d=0,c=0,t.mode=Cc;case Cc:if(t.flags&1024){for(;c<16;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}t.length=d,t.head&&(t.head.extra_len=d),t.flags&512&&t.wrap&4&&(H[0]=d&255,H[1]=d>>>8&255,t.check=jn(t.check,H,2,0)),d=0,c=0}else t.head&&(t.head.extra=null);t.mode=Ac;case Ac:if(t.flags&1024&&(m=t.length,m>h&&(m=h),m&&(t.head&&(N=t.head.extra_len-t.length,t.head.extra||(t.head.extra=new Uint8Array(t.head.extra_len)),t.head.extra.set(a.subarray(s,s+m),N)),t.flags&512&&t.wrap&4&&(t.check=jn(t.check,a,m,s)),h-=m,s+=m,t.length-=m),t.length))break e;t.length=0,t.mode=Fc;case Fc:if(t.flags&2048){if(h===0)break e;m=0;do N=a[s+m++],t.head&&N&&t.length<65536&&(t.head.name+=String.fromCharCode(N));while(N&&m<h);if(t.flags&512&&t.wrap&4&&(t.check=jn(t.check,a,m,s)),h-=m,s+=m,N)break e}else t.head&&(t.head.name=null);t.length=0,t.mode=Bc;case Bc:if(t.flags&4096){if(h===0)break e;m=0;do N=a[s+m++],t.head&&N&&t.length<65536&&(t.head.comment+=String.fromCharCode(N));while(N&&m<h);if(t.flags&512&&t.wrap&4&&(t.check=jn(t.check,a,m,s)),h-=m,s+=m,N)break e}else t.head&&(t.head.comment=null);t.mode=Sc;case Sc:if(t.flags&512){for(;c<16;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if(t.wrap&4&&d!==(t.check&65535)){n.msg="header crc mismatch",t.mode=Qe;break}d=0,c=0}t.head&&(t.head.hcrc=t.flags>>9&1,t.head.done=!0),n.adler=t.check=0,t.mode=cr;break;case Ic:for(;c<32;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}n.adler=t.check=Vc(d),d=0,c=0,t.mode=Qu;case Qu:if(t.havedict===0)return n.next_out=f,n.avail_out=_,n.next_in=s,n.avail_in=h,t.hold=d,t.bits=c,Rw;n.adler=t.check=1,t.mode=cr;case cr:if(e===Tw||e===Ku)break e;case of:if(t.last){d>>>=c&7,c-=c&7,t.mode=lf;break}for(;c<3;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}switch(t.last=d&1,d>>>=1,c-=1,d&3){case 0:t.mode=Tc;break;case 1:if(Uw(t),t.mode=Ju,e===Ku){d>>>=2,c-=2;break e}break;case 2:t.mode=Rc;break;case 3:n.msg="invalid block type",t.mode=Qe}d>>>=2,c-=2;break;case Tc:for(d>>>=c&7,c-=c&7;c<32;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if((d&65535)!==(d>>>16^65535)){n.msg="invalid stored block lengths",t.mode=Qe;break}if(t.length=d&65535,d=0,c=0,t.mode=ff,e===Ku)break e;case ff:t.mode=kc;case kc:if(m=t.length,m){if(m>h&&(m=h),m>_&&(m=_),m===0)break e;o.set(a.subarray(s,s+m),f),h-=m,s+=m,_-=m,f+=m,t.length-=m;break}t.mode=cr;break;case Rc:for(;c<14;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if(t.nlen=(d&31)+257,d>>>=5,c-=5,t.ndist=(d&31)+1,d>>>=5,c-=5,t.ncode=(d&15)+4,d>>>=4,c-=4,t.nlen>286||t.ndist>30){n.msg="too many length or distance symbols",t.mode=Qe;break}t.have=0,t.mode=Nc;case Nc:for(;t.have<t.ncode;){for(;c<3;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}t.lens[re[t.have++]]=d&7,d>>>=3,c-=3}for(;t.have<19;)t.lens[re[t.have++]]=0;if(t.lencode=t.lendyn,t.lenbits=7,Z={bits:t.lenbits},q=Xa(Iw,t.lens,0,19,t.lencode,0,t.work,Z),t.lenbits=Z.bits,q){n.msg="invalid code lengths set",t.mode=Qe;break}t.have=0,t.mode=$c;case $c:for(;t.have<t.nlen+t.ndist;){for(;I=t.lencode[d&(1<<t.lenbits)-1],k=I>>>24,U=I>>>16&255,$=I&65535,!(k<=c);){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if($<16)d>>>=k,c-=k,t.lens[t.have++]=$;else{if($===16){for(Y=k+2;c<Y;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if(d>>>=k,c-=k,t.have===0){n.msg="invalid bit length repeat",t.mode=Qe;break}N=t.lens[t.have-1],m=3+(d&3),d>>>=2,c-=2}else if($===17){for(Y=k+3;c<Y;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}d>>>=k,c-=k,N=0,m=3+(d&7),d>>>=3,c-=3}else{for(Y=k+7;c<Y;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}d>>>=k,c-=k,N=0,m=11+(d&127),d>>>=7,c-=7}if(t.have+m>t.nlen+t.ndist){n.msg="invalid bit length repeat",t.mode=Qe;break}for(;m--;)t.lens[t.have++]=N}}if(t.mode===Qe)break;if(t.lens[256]===0){n.msg="invalid code -- missing end-of-block",t.mode=Qe;break}if(t.lenbits=9,Z={bits:t.lenbits},q=Xa(_c,t.lens,0,t.nlen,t.lencode,0,t.work,Z),t.lenbits=Z.bits,q){n.msg="invalid literal/lengths set",t.mode=Qe;break}if(t.distbits=6,t.distcode=t.distdyn,Z={bits:t.distbits},q=Xa(vc,t.lens,t.nlen,t.ndist,t.distcode,0,t.work,Z),t.distbits=Z.bits,q){n.msg="invalid distances set",t.mode=Qe;break}if(t.mode=Ju,e===Ku)break e;case Ju:t.mode=ju;case ju:if(h>=6&&_>=258){n.next_out=f,n.avail_out=_,n.next_in=s,n.avail_in=h,t.hold=d,t.bits=c,Cw(n,x),f=n.next_out,o=n.output,_=n.avail_out,s=n.next_in,a=n.input,h=n.avail_in,d=t.hold,c=t.bits,t.mode===cr&&(t.back=-1);break}for(t.back=0;I=t.lencode[d&(1<<t.lenbits)-1],k=I>>>24,U=I>>>16&255,$=I&65535,!(k<=c);){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if(U&&!(U&240)){for(S=k,L=U,W=$;I=t.lencode[W+((d&(1<<S+L)-1)>>S)],k=I>>>24,U=I>>>16&255,$=I&65535,!(S+k<=c);){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}d>>>=S,c-=S,t.back+=S}if(d>>>=k,c-=k,t.back+=k,t.length=$,U===0){t.mode=Uc;break}if(U&32){t.back=-1,t.mode=cr;break}if(U&64){n.msg="invalid literal/length code",t.mode=Qe;break}t.extra=U&15,t.mode=Lc;case Lc:if(t.extra){for(Y=t.extra;c<Y;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}t.length+=d&(1<<t.extra)-1,d>>>=t.extra,c-=t.extra,t.back+=t.extra}t.was=t.length,t.mode=Oc;case Oc:for(;I=t.distcode[d&(1<<t.distbits)-1],k=I>>>24,U=I>>>16&255,$=I&65535,!(k<=c);){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if(!(U&240)){for(S=k,L=U,W=$;I=t.distcode[W+((d&(1<<S+L)-1)>>S)],k=I>>>24,U=I>>>16&255,$=I&65535,!(S+k<=c);){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}d>>>=S,c-=S,t.back+=S}if(d>>>=k,c-=k,t.back+=k,U&64){n.msg="invalid distance code",t.mode=Qe;break}t.offset=$,t.extra=U&15,t.mode=Pc;case Pc:if(t.extra){for(Y=t.extra;c<Y;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}t.offset+=d&(1<<t.extra)-1,d>>>=t.extra,c-=t.extra,t.back+=t.extra}if(t.offset>t.dmax){n.msg="invalid distance too far back",t.mode=Qe;break}t.mode=Mc;case Mc:if(_===0)break e;if(m=x-_,t.offset>m){if(m=t.offset-m,m>t.whave&&t.sane){n.msg="invalid distance too far back",t.mode=Qe;break}m>t.wnext?(m-=t.wnext,B=t.wsize-m):B=t.wnext-m,m>t.length&&(m=t.length),F=t.window}else F=o,B=f-t.offset,m=t.length;m>_&&(m=_),_-=m,t.length-=m;do o[f++]=F[B++];while(--m);t.length===0&&(t.mode=ju);break;case Uc:if(_===0)break e;o[f++]=t.length,_--,t.mode=ju;break;case lf:if(t.wrap){for(;c<32;){if(h===0)break e;h--,d|=a[s++]<<c,c+=8}if(x-=_,n.total_out+=x,t.total+=x,t.wrap&4&&x&&(n.adler=t.check=t.flags?jn(t.check,o,x,f-x):rf(t.check,o,x,f-x)),x=_,t.wrap&4&&(t.flags?d:Vc(d))!==t.check){n.msg="incorrect data check",t.mode=Qe;break}d=0,c=0}t.mode=Wc;case Wc:if(t.wrap&&t.flags){for(;c<32;){if(h===0)break e;h--,d+=a[s++]<<c,c+=8}if(t.wrap&4&&d!==(t.total&4294967295)){n.msg="incorrect length check",t.mode=Qe;break}d=0,c=0}t.mode=Gc;case Gc:q=kw;break e;case Qe:q=bc;break e;case qc:return mc;case Hc:default:return dn}return 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Ie().endianess(e).uint32("reductionLevel").uint32("reserved").uint64("dataOffset").uint64("indexOffset")}),a=new Ie().endianess(e).uint64("basesCovered").doublele("scoreMin").doublele("scoreMax").doublele("scoreSum").doublele("scoreSumSquares"),o=new Ie().endianess(e).uint32("magic").uint32("blockSize").uint32("keySize").uint32("valSize").uint64("itemCount"),s=new Ie().endianess(e).uint8("isLeafNode").skip(1).uint16("cnt").saveOffset("offset");return{chromTreeParser:o,totalSummaryParser:a,headerParser:t,isLeafNode:s}}class qb{getHeader(e){return this.headerP||(this.headerP=this._getHeader(e).catch(t=>{throw this.headerP=void 0,t})),this.headerP}constructor(e){const{filehandle:t,renameRefSeqs:a=f=>f,path:o,url:s}=e;if(this.renameRefSeqs=a,t)this.bbi=t;else if(s)this.bbi=new Zn(s);else if(o)this.bbi=new Fa(o);else throw new Error("no file given")}async _getHeader(e){const t=await this._getMainHeader(e),a=await this._readChromTree(t,e);return{...t,...a}}async _getMainHeader(e,t=2e3){const{buffer:a}=await this.bbi.read(Tn.alloc(t),0,t,0,e),o=this._isBigEndian(a),s=ld(o),f=s.headerParser.parse(a),{magic:h,asOffset:_,totalSummaryOffset:d}=f;if(f.fileType=h===xf?"bigbed":"bigwig",_>t||d>t)return this._getMainHeader(e,t*2);if(_){const c=Number(f.asOffset);f.autoSql=Gb(a.subarray(c,a.indexOf(0,c)))}if(f.totalSummaryOffset>t-8*5)return this._getMainHeader(e,t*2);if(f.totalSummaryOffset){const c=a.subarray(Number(f.totalSummaryOffset)),D=s.totalSummaryParser.parse(c);f.totalSummary={...D,basesCovered:Number(D.basesCovered)}}return{...f,isBigEndian:o}}_isBigEndian(e){let t=e.readInt32LE(0);if(t===fd||t===xf)return!1;if(t=e.readInt32BE(0),t===fd||t===xf)return!0;throw new Error("not a BigWig/BigBed file")}async _readChromTree(e,t){const a=e.isBigEndian,o=a?"big":"little",s=[],f={};let h=Number(e.unzoomedDataOffset);const _=Number(e.chromTreeOffset);for(;h%4!==0;)h+=1;const d=h-_,{buffer:c}=await this.bbi.read(Tn.alloc(d),0,d,Number(_),t),D=ld(a),{keySize:x}=D.chromTreeParser.parse(c),m=new Ie().endianess(o).string("key",{stripNull:!0,length:x}).uint32("refId").uint32("refSize").saveOffset("offset"),B=new Ie().endianess(o).skip(x).uint64("childOffset").saveOffset("offset"),F=32,I=async k=>{let U=k;if(U>=c.length)throw new Error("reading beyond end of buffer");const $=D.isLeafNode.parse(c.subarray(U)),{isLeafNode:S,cnt:L}=$;if(U+=$.offset,S)for(let W=0;W<L;W+=1){const N=m.parse(c.subarray(U));U+=N.offset;const{key:q,refId:H,refSize:Z}=N,Y={name:q,id:H,length:Z};f[this.renameRefSeqs(q)]=H,s[H]=Y}else{const W=[];for(let N=0;N<L;N+=1){const q=B.parse(c.subarray(U)),{childOffset:H}=q;U+=q.offset,W.push(I(Number(H)-Number(_)))}await Promise.all(W)}};return await I(F),{refsByName:f,refsByNumber:s}}async getUnzoomedView(e){const{unzoomedIndexOffset:t,refsByName:a,uncompressBufSize:o,isBigEndian:s,fileType:f}=await this.getHeader(e);return new ed(this.bbi,a,t,s,o>0,f)}async getFeatureStream(e,t,a,o){await this.getHeader(o);const s=this.renameRefSeqs(e);let f;const{basesPerSpan:h,scale:_}=o||{};return h?f=await this.getView(1/h,o):_?f=await this.getView(_,o):f=await this.getView(1,o),new Ib(d=>{f.readWigData(s,t,a,d,o).catch(c=>d.error(c))})}async getFeatures(e,t,a,o){const s=await this.getFeatureStream(e,t,a,o);return(await Ob(s.pipe(Wb()))).flat()}}let Hb=class extends qb{async getView(e,t){const{zoomLevels:a,refsByName:o,fileSize:s,isBigEndian:f,uncompressBufSize:h}=await this.getHeader(t),_=1/e;let d=a.length;s||(d-=1);for(let c=d;c>=0;c-=1){const D=a[c];if(D&&D.reductionLevel<=2*_){const x=Number(D.indexOffset);return new ed(this.bbi,o,x,f,h>0,"summary")}}return this.getUnzoomedView(t)}};class Ef{constructor(e){ue(this,"url");ue(this,"bw");this.url=e,this.bw=new Hb({filehandle:new Zn(e,{fetch:bo})})}async getData(e,t){const a=e.map(f=>{let h=t.ensemblStyle?f.chr.replace("chr",""):f.chr;return h==="M"&&(h="MT"),this.bw.getFeatures(h,f.start,f.end)}),o=await Promise.all(a);return e.forEach((f,h)=>{o[h].forEach(_=>_.chr=f.chr)}),Xt.flatten(o)}}const Vb=1e3;class Zb{constructor(e){ue(this,"maxBasesPerPixel");ue(this,"workerSource");this.maxBasesPerPixel=Vb,this.workerSource=new Ef(e)}getData(e,t,a){return t>this.maxBasesPerPixel?Promise.resolve([]):this.workerSource.getData(e,a)}}const Xb=2;class Kb{constructor(e){ue(this,"maxBasesPerPixel");ue(this,"workerSource");this.maxBasesPerPixel=Xb,this.workerSource=new Ef(e)}getData(e,t,a){return t>this.maxBasesPerPixel?Promise.resolve([]):this.workerSource.getData(e,a)}}var rs={InfoFields:{AA:{Number:1,Type:"String",Description:"Ancestral allele"},AC:{Number:"A",Type:"Integer",Description:"Allele count in genotypes, for each ALT allele, in the same order as listed"},AD:{Number:"R",Type:"Integer",Description:"Total read depth for each allele"},ADF:{Number:"R",Type:"Integer",Description:"Read depth for each allele on the forward strand"},ADR:{Number:"R",Type:"Integer",Description:"Read depth for each allele on the reverse strand"},AF:{Number:"A",Type:"Float",Description:"Allele frequency for each ALT allele in the same order as listed (estimated from primary data, not called genotypes)"},AN:{Number:1,Type:"Integer",Description:"Total number of alleles in called genotypes"},BQ:{Number:1,Type:"Float",Description:"RMS base quality"},CIGAR:{Number:1,Type:"Float",Description:"Cigar string describing how to align an alternate allele to the reference allele"},DB:{Number:0,Type:"Flag",Description:"dbSNP membership"},DP:{Number:1,Type:"Integer",Description:"combined depth across samples"},END:{Number:1,Type:"Integer",Description:"End position (for use with symbolic alleles)"},H2:{Number:0,Type:"Flag",Description:"HapMap2 membership"},H3:{Number:0,Type:"Flag",Description:"HapMap3 membership"},MQ:{Number:1,Type:null,Description:"RMS mapping quality"},MQ0:{Number:1,Type:"Integer",Description:"Number of MAPQ == 0 reads"},NS:{Number:1,Type:"Integer",Description:"Number of samples with data"},SB:{Number:4,Type:"Integer",Description:"Strand bias"},SOMATIC:{Number:0,Type:"Flag",Description:"Somatic mutation (for cancer genomics)"},VALIDATED:{Number:0,Type:"Flag",Description:"Validated by follow-up experiment"},"1000G":{Number:0,Type:"Flag",Description:"1000 Genomes membership"},IMPRECISE:{Number:0,Type:"Flag",Description:"Imprecise structural variation"},NOVEL:{Number:0,Type:"Flag",Description:"Indicates a novel structural variation"},SVTYPE:{Number:1,Type:"String",Description:"Type of structural variant"},SVLEN:{Number:null,Type:"Integer",Description:"Difference in length between REF and ALT alleles"},CIPOS:{Number:2,Type:"Integer",Description:"Confidence interval around POS for imprecise variants"},CIEND:{Number:2,Type:"Integer",Description:"Confidence interval around END for imprecise variants"},HOMLEN:{Type:"Integer",Description:"Length of base pair identical micro-homology at event breakpoints"},HOMSEQ:{Type:"String",Description:"Sequence of base pair identical micro-homology at event breakpoints"},BKPTID:{Type:"String",Description:"ID of the assembled alternate allele in the assembly file"},MEINFO:{Number:4,Type:"String",Description:"Mobile element info of the form NAME,START,END,POLARITY"},METRANS:{Number:4,Type:"String",Description:"Mobile element transduction info of the form CHR,START,END,POLARITY"},DGVID:{Number:1,Type:"String",Description:"ID of this element in Database of Genomic Variation"},DBVARID:{Number:1,Type:"String",Description:"ID of this element in DBVAR"},DBRIPID:{Number:1,Type:"String",Description:"ID of this element in DBRIP"},MATEID:{Number:null,Type:"String",Description:"ID of mate breakends"},PARID:{Number:1,Type:"String",Description:"ID of partner breakend"},EVENT:{Number:1,Type:"String",Description:"ID of event associated to breakend"},CILEN:{Number:2,Type:"Integer",Description:"Confidence interval around the inserted material between breakend"},DPADJ:{Type:"Integer",Description:"Read Depth of adjacency"},CN:{Number:1,Type:"Integer",Description:"Copy number of segment containing breakend"},CNADJ:{Number:null,Type:"Integer",Description:"Copy number of adjacency"},CICN:{Number:2,Type:"Integer",Description:"Confidence interval around copy number for the segment"},CICNADJ:{Number:null,Type:"Integer",Description:"Confidence interval around copy number for the adjacency"}},GenotypeFields:{AD:{Number:"R",Type:"Integer",Description:"Read depth for each allele"},ADF:{Number:"R",Type:"Integer",Description:"Read depth for each allele on the forward strand"},ADR:{Number:"R",Type:"Integer",Description:"Read depth for each allele on the reverse strand"},DP:{Number:1,Type:"Integer",Description:"Read depth"},EC:{Number:"A",Type:"Integer",Description:"Expected alternate allele counts"},FT:{Number:1,Type:"String",Description:'Filter indicating if this genotype was "called"'},GL:{Number:"G",Type:"Float",Description:"Genotype likelihoods"},GP:{Number:"G",Type:"Float",Description:"Genotype posterior probabilities"},GQ:{Number:1,Type:"Integer",Description:"Conditional genotype quality"},GT:{Number:1,Type:"String",Description:"Genotype"},HQ:{Number:2,Type:"Integer",Description:"Haplotype quality"},MQ:{Number:1,Type:"Integer",Description:"RMS mapping quality"},PL:{Number:"G",Type:"Integer",Description:"Phred-scaled genotype likelihoods rounded to the closest integer"},PQ:{Number:1,Type:"Integer",Description:"Phasing quality"},PS:{Number:1,Type:"Integer",Description:"Phase set"}},AltTypes:{DEL:{Description:"Deletion relative to the reference"},INS:{Description:"Insertion of novel sequence relative to the reference"},DUP:{Description:"Region of elevated copy number relative to the reference"},INV:{Description:"Inversion of reference sequence"},CNV:{Description:"Copy number variable region (may be both deletion and duplication)"},"DUP:TANDEM":{Description:"Tandem duplication"},"DEL:ME":{Description:"Deletion of mobile element relative to the reference"},"INS:ME":{Description:"Insertion of a mobile element relative to the reference"},NON_REF:{Description:"Represents any possible alternative allele at this location"},"*":{Description:"Represents any possible alternative allele at this location"}},FilterTypes:{PASS:{Description:"Passed all filters"}}};function Yb(n){Object.assign(this,n)}function Qb(n){try{return decodeURIComponent(n)}catch{return n}}class Jb{constructor({header:e="",strict:t=!0}){if(!e||!e.length)throw new Error("empty header received");const a=e.split(/[\r\n]+/).filter(_=>_);if(!a.length)throw new Error("no non-empty header lines specified");this.strict=t,this.metadata=JSON.parse(JSON.stringify({INFO:rs.InfoFields,FORMAT:rs.GenotypeFields,ALT:rs.AltTypes,FILTER:rs.FilterTypes}));let o;if(a.forEach(_=>{if(_.startsWith("#"))_.startsWith("##")?this._parseMetadata(_):o=_;else throw new Error(`Bad line in header:
-${_}`)}),!o)throw new Error("No format line found in header");const s=o.trim().split("	"),f=s.slice(0,8),h=["#CHROM","POS","ID","REF","ALT","QUAL","FILTER","INFO"];if(s.length<8)throw new Error(`VCF header missing columns:
-${o}`);if(f.length!==h.length||!f.every((_,d)=>_===h[d]))throw new Error(`VCF column headers not correct:
-${o}`);this.samples=s.slice(9)}_parseGenotypes(e,t){const a=t.split("	"),o={},s=e==null?void 0:e.split(":");return s&&this.samples.forEach((f,h)=>{o[f]={},s.forEach(_=>{o[f][_]=null}),a[h].split(":").filter(_=>_).forEach((_,d)=>{let c;if(_===""||_==="."||_===void 0)c=null;else{const D=_.split(",").map(m=>m==="."?null:m),x=this.getMetadata("FORMAT",s[d],"Type");x==="Integer"||x==="Float"?c=D.map(m=>m&&+m):c=D}o[f][s[d]]=c},{})}),o}_parseMetadata(e){const t=e.trim().match(/^##(.+?)=(.*)/);if(!t)throw new Error(`Line is not a valid metadata line: ${e}`);const[a,o]=t.slice(1,3);if(o.startsWith("<")){a in this.metadata||(this.metadata[a]={});const[s,f]=this._parseStructuredMetaVal(o);this.metadata[a][s]=f}else this.metadata[a]=o}_parseStructuredMetaVal(e){const t=this._parseKeyValue(e.replace(/^<|>$/g,""),","),a=t.ID;return delete t.ID,"Number"in t&&(Number.isNaN(Number(t.Number))||(t.Number=Number(t.Number))),[a,t]}getMetadata(...e){let t=this.metadata;for(let a=0;a<e.length;a+=1)if(t=t[e[a]],!t)return t;return t}_parseKeyValue(e,t=";"){const a={};let o="",s="",f=1;for(let h=0;h<e.length;h+=1)f===1?e[h]==="="?f=2:e[h]!==t?o+=e[h]:s===""&&(a[o]=null,o=""):f===2?e[h]===t?(a[o]=s,o="",s="",f=1):e[h]==='"'?f=3:s+=e[h]:f===3&&(e[h]!=='"'?s+=e[h]:f=2);return f===2||f===3?a[o]=s:f===1&&(a[o]=null),a}parseLine(e){if(e=e.trim(),!e.length)return;const t=this;let a=0;for(let W=0;a<e.length&&(e[a]==="	"&&(W+=1),W!==9);a+=1);const o=e.substr(0,a).split("	"),s=e.substr(a+1),[f,h,_,d,c,D,x]=o,m=f,B=+h,F=_==="."?null:_.split(";"),I=d,k=c==="."?null:c.split(","),U=D==="."?null:+D,$=x==="."?null:x.split(";");if(this.strict&&o[7]===void 0)throw new Error("no INFO field specified, must contain at least a '.' (turn off strict mode to allow)");const S=o[7]===void 0||o[7]==="."?{}:this._parseKeyValue(o[7]);Object.keys(S).forEach(W=>{let N;S[W]?N=S[W].split(",").map(H=>H==="."?null:H).map(H=>H&&Qb(H)):N=S[W];const q=this.getMetadata("INFO",W,"Type");q&&(q==="Integer"||q==="Float"?N=N.map(H=>H===null?null:Number(H)):q==="Flag"&&(S[W]?console.warn(`Info field ${W} is a Flag and should not have a value (got value ${S[W]})`):N=!0)),S[W]=N});const L=new Yb({CHROM:m,POS:B,ALT:k,INFO:S,REF:I,FILTER:$&&$.length===1&&$[0]==="PASS"?"PASS":$,ID:F,QUAL:U});return Object.defineProperty(L,"SAMPLES",{get(){const W=t._parseGenotypes(o[8],s);return Object.defineProperty(this,"SAMPLES",{value:W,configurable:!1}),W},configurable:!0}),L}}class jb{constructor(e,t=null){ue(this,"header");ue(this,"vcf");ue(this,"parser");let a,o;Array.isArray(e)?(a=new ph(e.filter(s=>!s.name.endsWith(".tbi"))[0]),o=new ph(e.filter(s=>s.name.endsWith(".tbi"))[0])):(a=new Zn(e),o=new Zn(t||e+".tbi")),this.vcf=new ac({filehandle:a,tbiFilehandle:o}),this.header=null,this.parser=null}async getData(e,t,a){this.header||(this.header=await this.vcf.getHeader()),this.parser||(this.parser=new Jb({header:this.header}));const o=e.map(h=>this._getDataInLocus(h,a)),s=await Promise.all(o);return Xt.flatten(s)}async _getDataInLocus(e,t){const a=[];let o=t&&t.ensemblStyle?e.chr.replace("chr",""):e.chr;if(o==="M"&&(o="MT"),await this.vcf.getLines(o,e.start+1,e.end,s=>a.push(this.parser.parseLine(s))),t&&t.ensemblStyle)for(let s of a)s.CHROM=e.chr;return a}}const zb={AUTO:"auto"};function Gt(n,e){if(typeof n!="number"||typeof e!="number")throw"Bad range "+n+","+e;this._min=n,this._max=e}Gt.prototype.min=function(){return this._min},Gt.prototype.max=function(){return this._max},Gt.prototype.contains=function(n){return n>=this._min&&n<=this._max},Gt.prototype.isContiguous=function(){return!0},Gt.prototype.ranges=function(){return[this]},Gt.prototype._pushRanges=function(n){n.push(this)},Gt.prototype.toString=function(){return"["+this._min+"-"+this._max+"]"};function pn(n){var e=n.sort(hd),t=[],a=e.shift();e.forEach(function(o){o._min<=a._max?o._max>a._max&&(a._max=o._max):(t.push(a),a=o)}),t.push(a),this._ranges=t}pn.prototype.min=function(){return this._ranges[0].min()},pn.prototype.max=function(){return this._ranges[this._ranges.length-1].max()},pn.prototype.lower_bound=function(n){var e=this.ranges();if(n>this.max())return e.length;if(n<this.min())return 0;for(var t=0,a=e.length-1;t<=a;){var o=Math.floor((t+a)/2);if(n>e[o]._max)t=o+1;else if(n<e[o]._min)a=o-1;else return o}return t},pn.prototype.contains=function(n){var e=this.lower_bound(n);return!!(e<this._ranges.length&&this._ranges[e].contains(n))},pn.prototype.insertRange=function(n){var e=this.lower_bound(n._min);if(e===this._ranges.length){this._ranges.push(n);return}var t=this.ranges();if(n._max<t[e]._min){this._ranges.splice(e,0,n);return}t[e]._min<n._min&&(n._min=t[e]._min);for(var a=e+1;a<t.length&&t[a]._min<=n._max;)a++;a--,t[a]._max>n._max&&(n._max=t[a]._max),this._ranges.splice(e,a-e+1,n)},pn.prototype.isContiguous=function(){return this._ranges.length>1},pn.prototype.ranges=function(){return this._ranges},pn.prototype._pushRanges=function(n){for(var e=0;e<this._ranges.length;++e)n.push(this._ranges[e])},pn.prototype.toString=function(){for(var n="",e=0;e<this._ranges.length;++e)e>0&&(n=n+","),n=n+this._ranges[e].toString();return n};function em(n,e){return n instanceof pn||(n instanceof Array||(n=[n]),n=new pn(n)),e&&n.insertRange(e),n}function tm(n,e){for(var t=n.ranges(),a=e.ranges(),o=t.length,s=a.length,f=0,h=0,_=[];f<o&&h<s;){var n=t[f],e=a[h],d=Math.max(n.min(),e.min()),c=Math.min(n.max(),e.max());c>=d&&_.push(new Gt(d,c)),n.max()>e.max()?++h:++f}return _.length==0?null:_.length==1?_[0]:new pn(_)}function nm(n){for(var e=0,t=n.ranges(),a=0;a<t.length;++a){var o=t[a];e+=o.max()-o.min()+1}return e}function rm(n,e){return n.min()<e.min()?-1:n.min()>e.min()?1:n.max()<e.max()?-1:e.max()>n.max()?1:0}function hd(n,e){return n._min<e._min?-1:n._min>e._min?1:n._max<e._max?-1:e._max>n._max?1:0}typeof module<"u"&&(module.exports={Range:Gt,union:em,intersection:tm,coverage:nm,rangeOver:rm,_rangeOrder:hd});var im=15,cd=im,dd=1440,Or=15,am=32,um=0,sm=4,om=8,Be=0,pr=1,fm=2,gn=-2,qe=-3,pd=-4,er=-5,gd=0,_d=1,vd=2,wd=3,bd=4,md=5,Cf=6,Ya=7,Dd=8,yd=9,xd=10,Ed=11,is=12,_n=13,Yt=[0,1,3,7,15,31,63,127,255,511,1023,2047,4095,8191,16383,32767,65535],Ji=0,Af=1,Cd=2,Ad=3,Fd=4,Bd=5,as=6,us=7,lm=8,ss=9,hm=9,cm=5,dm=[96,7,256,0,8,80,0,8,16,84,8,115,82,7,31,0,8,112,0,8,48,0,9,192,80,7,10,0,8,96,0,8,32,0,9,160,0,8,0,0,8,128,0,8,64,0,9,224,80,7,6,0,8,88,0,8,24,0,9,144,83,7,59,0,8,120,0,8,56,0,9,208,81,7,17,0,8,104,0,8,40,0,9,176,0,8,8,0,8,136,0,8,72,0,9,240,80,7,4,0,8,84,0,8,20,85,8,227,83,7,43,0,8,116,0,8,52,0,9,200,81,7,13,0,8,100,0,8,36,0,9,168,0,8,4,0,8,132,0,8,68,0,9,232,80,7,8,0,8,92,0,8,28,0,9,152,84,7,83,0,8,124,0,8,60,0,9,216,82,7,23,0,8,108,0,8,44,0,9,184,0,8,12,0,8,140,0,8,76,0,9,248,80,7,3,0,8,82,0,8,18,85,8,163,83,7,35,0,8,114,0,8,50,0,9,196,81,7,11,0,8,98,0,8,34,0,9,164,0,8,2,0,8,130,0,8,66,0,9,228,80,7,7,0,8,90,0,8,26,0,9,148,84,7,67,0,8,122,0,8,58,0,9,212,82,7,19,0,8,106,0,8,42,0,9,180,0,8,10,0,8,138,0,8,74,0,9,244,80,7,5,0,8,86,0,8,22,192,8,0,83,7,51,0,8,118,0,8,54,0,9,204,81,7,15,0,8,102,0,8,38,0,9,172,0,8,6,0,8,134,0,8,70,0,9,236,80,7,9,0,8,94,0,8,30,0,9,156,84,7,99,0,8,126,0,8,62,0,9,220,82,7,27,0,8,110,0,8,46,0,9,188,0,8,14,0,8,142,0,8,78,0,9,252,96,7,256,0,8,81,0,8,17,85,8,131,82,7,31,0,8,113,0,8,49,0,9,194,80,7,10,0,8,97,0,8,33,0,9,162,0,8,1,0,8,129,0,8,65,0,9,226,80,7,6,0,8,89,0,8,25,0,9,146,83,7,59,0,8,121,0,8,57,0,9,210,81,7,17,0,8,105,0,8,41,0,9,178,0,8,9,0,8,137,0,8,73,0,9,242,80,7,4,0,8,85,0,8,21,80,8,258,83,7,43,0,8,117,0,8,53,0,9,202,81,7,13,0,8,101,0,8,37,0,9,170,0,8,5,0,8,133,0,8,69,0,9,234,80,7,8,0,8,93,0,8,29,0,9,154,84,7,83,0,8,125,0,8,61,0,9,218,82,7,23,0,8,109,0,8,45,0,9,186,0,8,13,0,8,141,0,8,77,0,9,250,80,7,3,0,8,83,0,8,19,85,8,195,83,7,35,0,8,115,0,8,51,0,9,198,81,7,11,0,8,99,0,8,35,0,9,166,0,8,3,0,8,131,0,8,67,0,9,230,80,7,7,0,8,91,0,8,27,0,9,150,84,7,67,0,8,123,0,8,59,0,9,214,82,7,19,0,8,107,0,8,43,0,9,182,0,8,11,0,8,139,0,8,75,0,9,246,80,7,5,0,8,87,0,8,23,192,8,0,83,7,51,0,8,119,0,8,55,0,9,206,81,7,15,0,8,103,0,8,39,0,9,174,0,8,7,0,8,135,0,8,71,0,9,238,80,7,9,0,8,95,0,8,31,0,9,158,84,7,99,0,8,127,0,8,63,0,9,222,82,7,27,0,8,111,0,8,47,0,9,190,0,8,15,0,8,143,0,8,79,0,9,254,96,7,256,0,8,80,0,8,16,84,8,115,82,7,31,0,8,112,0,8,48,0,9,193,80,7,10,0,8,96,0,8,32,0,9,161,0,8,0,0,8,128,0,8,64,0,9,225,80,7,6,0,8,88,0,8,24,0,9,145,83,7,59,0,8,120,0,8,56,0,9,209,81,7,17,0,8,104,0,8,40,0,9,177,0,8,8,0,8,136,0,8,72,0,9,241,80,7,4,0,8,84,0,8,20,85,8,227,83,7,43,0,8,116,0,8,52,0,9,201,81,7,13,0,8,100,0,8,36,0,9,169,0,8,4,0,8,132,0,8,68,0,9,233,80,7,8,0,8,92,0,8,28,0,9,153,84,7,83,0,8,124,0,8,60,0,9,217,82,7,23,0,8,108,0,8,44,0,9,185,0,8,12,0,8,140,0,8,76,0,9,249,80,7,3,0,8,82,0,8,18,85,8,163,83,7,35,0,8,114,0,8,50,0,9,197,81,7,11,0,8,98,0,8,34,0,9,165,0,8,2,0,8,130,0,8,66,0,9,229,80,7,7,0,8,90,0,8,26,0,9,149,84,7,67,0,8,122,0,8,58,0,9,213,82,7,19,0,8,106,0,8,42,0,9,181,0,8,10,0,8,138,0,8,74,0,9,245,80,7,5,0,8,86,0,8,22,192,8,0,83,7,51,0,8,118,0,8,54,0,9,205,81,7,15,0,8,102,0,8,38,0,9,173,0,8,6,0,8,134,0,8,70,0,9,237,80,7,9,0,8,94,0,8,30,0,9,157,84,7,99,0,8,126,0,8,62,0,9,221,82,7,27,0,8,110,0,8,46,0,9,189,0,8,14,0,8,142,0,8,78,0,9,253,96,7,256,0,8,81,0,8,17,85,8,131,82,7,31,0,8,113,0,8,49,0,9,195,80,7,10,0,8,97,0,8,33,0,9,163,0,8,1,0,8,129,0,8,65,0,9,227,80,7,6,0,8,89,0,8,25,0,9,147,83,7,59,0,8,121,0,8,57,0,9,211,81,7,17,0,8,105,0,8,41,0,9,179,0,8,9,0,8,137,0,8,73,0,9,243,80,7,4,0,8,85,0,8,21,80,8,258,83,7,43,0,8,117,0,8,53,0,9,203,81,7,13,0,8,101,0,8,37,0,9,171,0,8,5,0,8,133,0,8,69,0,9,235,80,7,8,0,8,93,0,8,29,0,9,155,84,7,83,0,8,125,0,8,61,0,9,219,82,7,23,0,8,109,0,8,45,0,9,187,0,8,13,0,8,141,0,8,77,0,9,251,80,7,3,0,8,83,0,8,19,85,8,195,83,7,35,0,8,115,0,8,51,0,9,199,81,7,11,0,8,99,0,8,35,0,9,167,0,8,3,0,8,131,0,8,67,0,9,231,80,7,7,0,8,91,0,8,27,0,9,151,84,7,67,0,8,123,0,8,59,0,9,215,82,7,19,0,8,107,0,8,43,0,9,183,0,8,11,0,8,139,0,8,75,0,9,247,80,7,5,0,8,87,0,8,23,192,8,0,83,7,51,0,8,119,0,8,55,0,9,207,81,7,15,0,8,103,0,8,39,0,9,175,0,8,7,0,8,135,0,8,71,0,9,239,80,7,9,0,8,95,0,8,31,0,9,159,84,7,99,0,8,127,0,8,63,0,9,223,82,7,27,0,8,111,0,8,47,0,9,191,0,8,15,0,8,143,0,8,79,0,9,255],pm=[80,5,1,87,5,257,83,5,17,91,5,4097,81,5,5,89,5,1025,85,5,65,93,5,16385,80,5,3,88,5,513,84,5,33,92,5,8193,82,5,9,90,5,2049,86,5,129,192,5,24577,80,5,2,87,5,385,83,5,25,91,5,6145,81,5,7,89,5,1537,85,5,97,93,5,24577,80,5,4,88,5,769,84,5,49,92,5,12289,82,5,13,90,5,3073,86,5,193,192,5,24577],gm=[3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0],_m=[0,0,0,0,0,0,0,0,1,1,1,1,2,2,2,2,3,3,3,3,4,4,4,4,5,5,5,5,0,112,112],vm=[1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577],wm=[0,0,0,0,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13];function ji(){}ji.prototype.inflateInit=function(n,e){return n||(n=cd),e&&(e=!1),this.istate=new Pr,this.istate.inflateInit(this,e?-n:n)},ji.prototype.inflate=function(n){return this.istate==null?gn:this.istate.inflate(this,n)},ji.prototype.inflateEnd=function(){if(this.istate==null)return gn;var n=istate.inflateEnd(this);return this.istate=null,n},ji.prototype.inflateSync=function(){return istate.inflateSync(this)},ji.prototype.inflateSetDictionary=function(n,e){return istate.inflateSetDictionary(this,n,e)};function Pr(){this.was=[0]}Pr.prototype.inflateReset=function(n){return n==null||n.istate==null?gn:(n.total_in=n.total_out=0,n.msg=null,n.istate.mode=n.istate.nowrap!=0?Ya:gd,n.istate.blocks.reset(n,null),Be)},Pr.prototype.inflateEnd=function(n){return this.blocks!=null&&this.blocks.free(n),this.blocks=null,Be},Pr.prototype.inflateInit=function(n,e){return n.msg=null,this.blocks=null,e<0&&(e=-e),e<8||e>15?(this.inflateEnd(n),gn):(this.wbits=e,n.istate.blocks=new vi(n,n.istate.nowrap!=0?null:this,1<<e),this.inflateReset(n),Be)},Pr.prototype.inflate=function(n,e){var t,a;if(n==null||n.istate==null||n.next_in==null)return gn;for(e=e==sm?er:Be,t=er;;)switch(n.istate.mode){case gd:if(n.avail_in==0)return t;if(t=e,n.avail_in--,n.total_in++,((n.istate.method=n.next_in[n.next_in_index++])&15)!=om){n.istate.mode=_n,n.msg="unknown compression method",n.istate.marker=5;break}if((n.istate.method>>4)+8>n.istate.wbits){n.istate.mode=_n,n.msg="invalid window size",n.istate.marker=5;break}n.istate.mode=_d;case _d:if(n.avail_in==0)return t;if(t=e,n.avail_in--,n.total_in++,a=n.next_in[n.next_in_index++]&255,((n.istate.method<<8)+a)%31!=0){n.istate.mode=_n,n.msg="incorrect header check",n.istate.marker=5;break}if(!(a&am)){n.istate.mode=Ya;break}n.istate.mode=vd;case vd:if(n.avail_in==0)return t;t=e,n.avail_in--,n.total_in++,n.istate.need=(n.next_in[n.next_in_index++]&255)<<24&4278190080,n.istate.mode=wd;case wd:if(n.avail_in==0)return t;t=e,n.avail_in--,n.total_in++,n.istate.need+=(n.next_in[n.next_in_index++]&255)<<16&16711680,n.istate.mode=bd;case bd:if(n.avail_in==0)return t;t=e,n.avail_in--,n.total_in++,n.istate.need+=(n.next_in[n.next_in_index++]&255)<<8&65280,n.istate.mode=md;case md:return n.avail_in==0?t:(t=e,n.avail_in--,n.total_in++,n.istate.need+=n.next_in[n.next_in_index++]&255,n.adler=n.istate.need,n.istate.mode=Cf,fm);case Cf:return n.istate.mode=_n,n.msg="need dictionary",n.istate.marker=0,gn;case Ya:if(t=n.istate.blocks.proc(n,t),t==qe){n.istate.mode=_n,n.istate.marker=0;break}if(t==Be&&(t=e),t!=pr)return t;if(t=e,n.istate.blocks.reset(n,n.istate.was),n.istate.nowrap!=0){n.istate.mode=is;break}n.istate.mode=Dd;case Dd:if(n.avail_in==0)return t;t=e,n.avail_in--,n.total_in++,n.istate.need=(n.next_in[n.next_in_index++]&255)<<24&4278190080,n.istate.mode=yd;case yd:if(n.avail_in==0)return t;t=e,n.avail_in--,n.total_in++,n.istate.need+=(n.next_in[n.next_in_index++]&255)<<16&16711680,n.istate.mode=xd;case xd:if(n.avail_in==0)return t;t=e,n.avail_in--,n.total_in++,n.istate.need+=(n.next_in[n.next_in_index++]&255)<<8&65280,n.istate.mode=Ed;case Ed:if(n.avail_in==0)return t;if(t=e,n.avail_in--,n.total_in++,n.istate.need+=n.next_in[n.next_in_index++]&255,n.istate.was[0]!=n.istate.need){n.istate.mode=_n,n.msg="incorrect data check",n.istate.marker=5;break}n.istate.mode=is;case is:return pr;case _n:return qe;default:return gn}},Pr.prototype.inflateSetDictionary=function(n,e,t){var a=0,o=t;return n==null||n.istate==null||n.istate.mode!=Cf?gn:n._adler.adler32(1,e,0,t)!=n.adler?qe:(n.adler=n._adler.adler32(0,null,0,0),o>=1<<n.istate.wbits&&(o=(1<<n.istate.wbits)-1,a=t-o),n.istate.blocks.set_dictionary(e,a,o),n.istate.mode=Ya,Be)};var bm=[0,0,255,255];Pr.prototype.inflateSync=function(n){var e,t,a,o,s;if(n==null||n.istate==null)return gn;if(n.istate.mode!=_n&&(n.istate.mode=_n,n.istate.marker=0),(e=n.avail_in)==0)return er;for(t=n.next_in_index,a=n.istate.marker;e!=0&&a<4;)n.next_in[t]==bm[a]?a++:n.next_in[t]!=0?a=0:a=4-a,t++,e--;return n.total_in+=t-n.next_in_index,n.next_in_index=t,n.avail_in=e,n.istate.marker=a,a!=4?qe:(o=n.total_in,s=n.total_out,this.inflateReset(n),n.total_in=o,n.total_out=s,n.istate.mode=Ya,Be)},Pr.prototype.inflateSyncPoint=function(n){return n==null||n.istate==null||n.istate.blocks==null?gn:n.istate.blocks.sync_point()};var Sd=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15];function vi(n,e,t){this.hufts=new Int32Array(dd*3),this.window=new Uint8Array(t),this.end=t,this.checkfn=e,this.mode=Ji,this.reset(n,null),this.left=0,this.table=0,this.index=0,this.blens=null,this.bb=new Int32Array(1),this.tb=new Int32Array(1),this.codes=new Qa,this.last=0,this.bitk=0,this.bitb=0,this.read=0,this.write=0,this.check=0,this.inftree=new Ja}vi.prototype.reset=function(n,e){e&&(e[0]=this.check),this.mode==as&&this.codes.free(n),this.mode=Ji,this.bitk=0,this.bitb=0,this.read=this.write=0,this.checkfn&&(n.adler=this.check=n._adler.adler32(0,null,0,0))},vi.prototype.proc=function(n,e){var t,a,o,s,f,h,_;for(s=n.next_in_index,f=n.avail_in,a=this.bitb,o=this.bitk,h=this.write,_=h<this.read?this.read-h-1:this.end-h;;)switch(this.mode){case Ji:for(;o<3;){if(f!=0)e=Be;else return this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e);f--,a|=(n.next_in[s++]&255)<<o,o+=8}switch(t=a&7,this.last=t&1,t>>>1){case 0:a>>>=3,o-=3,t=o&7,a>>>=t,o-=t,this.mode=Af;break;case 1:{var d=new Int32Array(1),c=new Int32Array(1),D=[],x=[];mm(d,c,D,x),this.codes.init(d[0],c[0],D[0],0,x[0],0,n)}a>>>=3,o-=3,this.mode=as;break;case 2:a>>>=3,o-=3,this.mode=Ad;break;case 3:return a>>>=3,o-=3,this.mode=_n,n.msg="invalid block type",e=qe,this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e)}break;case Af:for(;o<32;){if(f!=0)e=Be;else return this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e);f--,a|=(n.next_in[s++]&255)<<o,o+=8}if((~a>>>16&65535)!=(a&65535))return this.mode=_n,n.msg="invalid stored block lengths",e=qe,this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e);this.left=a&65535,a=o=0,this.mode=this.left!=0?Cd:this.last!=0?us:Ji;break;case Cd:if(f==0)return this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,write=h,this.inflate_flush(n,e);if(_==0&&(h==end&&read!=0&&(h=0,_=h<this.read?this.read-h-1:this.end-h),_==0&&(this.write=h,e=this.inflate_flush(n,e),h=this.write,_=h<this.read?this.read-h-1:this.end-h,h==this.end&&this.read!=0&&(h=0,_=h<this.read?this.read-h-1:this.end-h),_==0)))return this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e);if(e=Be,t=this.left,t>f&&(t=f),t>_&&(t=_),On(n.next_in,s,this.window,h,t),s+=t,f-=t,h+=t,_-=t,(this.left-=t)!=0)break;this.mode=this.last!=0?us:Ji;break;case Ad:for(;o<14;){if(f!=0)e=Be;else return this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e);f--,a|=(n.next_in[s++]&255)<<o,o+=8}if(this.table=t=a&16383,(t&31)>29||(t>>5&31)>29)return this.mode=ss,n.msg="too many length or distance symbols",e=qe,this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e);if(t=258+(t&31)+(t>>5&31),this.blens==null||this.blens.length<t)this.blens=new Int32Array(t);else for(var m=0;m<t;m++)this.blens[m]=0;a>>>=14,o-=14,this.index=0;let I=Fd;case Fd:for(;this.index<4+(this.table>>>10);){for(;o<3;){if(f!=0)e=Be;else return this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e);f--,a|=(n.next_in[s++]&255)<<o,o+=8}this.blens[Sd[this.index++]]=a&7,a>>>=3,o-=3}for(;this.index<19;)this.blens[Sd[this.index++]]=0;if(this.bb[0]=7,t=this.inftree.inflate_trees_bits(this.blens,this.bb,this.tb,this.hufts,n),t!=Be)return e=t,e==qe&&(this.blens=null,this.mode=ss),this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,write=h,this.inflate_flush(n,e);this.index=0,this.mode=Bd;case Bd:for(;t=this.table,this.index<258+(t&31)+(t>>5&31);){var m,B,F;for(t=this.bb[0];o<t;){if(f!=0)e=Be;else return this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e);f--,a|=(n.next_in[s++]&255)<<o,o+=8}if(t=this.hufts[(this.tb[0]+(a&Yt[t]))*3+1],F=this.hufts[(this.tb[0]+(a&Yt[t]))*3+2],F<16)a>>>=t,o-=t,this.blens[this.index++]=F;else{for(m=F==18?7:F-14,B=F==18?11:3;o<t+m;){if(f!=0)e=Be;else return this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e);f--,a|=(n.next_in[s++]&255)<<o,o+=8}if(a>>>=t,o-=t,B+=a&Yt[m],a>>>=m,o-=m,m=this.index,t=this.table,m+B>258+(t&31)+(t>>5&31)||F==16&&m<1)return this.blens=null,this.mode=ss,n.msg="invalid bit length repeat",e=qe,this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e);F=F==16?this.blens[m-1]:0;do this.blens[m++]=F;while(--B!=0);this.index=m}}this.tb[0]=-1;{var d=new Int32Array(1),c=new Int32Array(1),D=new Int32Array(1),x=new Int32Array(1);if(d[0]=9,c[0]=6,t=this.table,t=this.inftree.inflate_trees_dynamic(257+(t&31),1+(t>>5&31),this.blens,d,c,D,x,this.hufts,n),t!=Be)return t==qe&&(this.blens=null,this.mode=_n),e=t,this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e);this.codes.init(d[0],c[0],this.hufts,D[0],this.hufts,x[0],n)}this.mode=as;case as:if(this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,(e=this.codes.proc(this,n,e))!=pr)return this.inflate_flush(n,e);if(e=Be,this.codes.free(n),s=n.next_in_index,f=n.avail_in,a=this.bitb,o=this.bitk,h=this.write,_=h<this.read?this.read-h-1:this.end-h,this.last==0){this.mode=Ji;break}this.mode=us;case us:if(this.write=h,e=this.inflate_flush(n,e),h=this.write,_=h<this.read?this.read-h-1:this.end-h,this.read!=this.write)return this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e);I=is;case lm:return e=pr,this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e);case ss:return e=qe,this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e);default:return e=gn,this.bitb=a,this.bitk=o,n.avail_in=f,n.total_in+=s-n.next_in_index,n.next_in_index=s,this.write=h,this.inflate_flush(n,e)}},vi.prototype.free=function(n){this.reset(n,null),this.window=null,this.hufts=null},vi.prototype.set_dictionary=function(n,e,t){On(n,e,window,0,t),this.read=this.write=t},vi.prototype.sync_point=function(){return this.mode==Af},vi.prototype.inflate_flush=function(n,e){var t,a,o;return a=n.next_out_index,o=this.read,t=(o<=this.write?this.write:this.end)-o,t>n.avail_out&&(t=n.avail_out),t!=0&&e==er&&(e=Be),n.avail_out-=t,n.total_out+=t,this.checkfn!=null&&(n.adler=this.check=n._adler.adler32(this.check,this.window,o,t)),On(this.window,o,n.next_out,a,t),a+=t,o+=t,o==this.end&&(o=0,this.write==this.end&&(this.write=0),t=this.write-o,t>n.avail_out&&(t=n.avail_out),t!=0&&e==er&&(e=Be),n.avail_out-=t,n.total_out+=t,this.checkfn!=null&&(n.adler=this.check=n._adler.adler32(this.check,this.window,o,t)),On(this.window,o,n.next_out,a,t),a+=t,o+=t),n.next_out_index=a,this.read=o,e};var os=0,Id=1,Td=2,kd=3,Rd=4,Nd=5,$d=6,Ff=7,Ld=8,fs=9;function Qa(){}Qa.prototype.init=function(n,e,t,a,o,s,f){this.mode=os,this.lbits=n,this.dbits=e,this.ltree=t,this.ltree_index=a,this.dtree=o,this.dtree_index=s,this.tree=null},Qa.prototype.proc=function(n,e,t){var a,o,s,f=0,h=0,_=0,d,c,D,x;for(_=e.next_in_index,d=e.avail_in,f=n.bitb,h=n.bitk,c=n.write,D=c<n.read?n.read-c-1:n.end-c;;)switch(this.mode){case os:if(D>=258&&d>=10&&(n.bitb=f,n.bitk=h,e.avail_in=d,e.total_in+=_-e.next_in_index,e.next_in_index=_,n.write=c,t=this.inflate_fast(this.lbits,this.dbits,this.ltree,this.ltree_index,this.dtree,this.dtree_index,n,e),_=e.next_in_index,d=e.avail_in,f=n.bitb,h=n.bitk,c=n.write,D=c<n.read?n.read-c-1:n.end-c,t!=Be)){this.mode=t==pr?Ff:fs;break}this.need=this.lbits,this.tree=this.ltree,this.tree_index=this.ltree_index,this.mode=Id;case Id:for(a=this.need;h<a;){if(d!=0)t=Be;else return n.bitb=f,n.bitk=h,e.avail_in=d,e.total_in+=_-e.next_in_index,e.next_in_index=_,n.write=c,n.inflate_flush(e,t);d--,f|=(e.next_in[_++]&255)<<h,h+=8}if(o=(this.tree_index+(f&Yt[a]))*3,f>>>=this.tree[o+1],h-=this.tree[o+1],s=this.tree[o],s==0){this.lit=this.tree[o+2],this.mode=$d;break}if(s&16){this.get=s&15,this.len=this.tree[o+2],this.mode=Td;break}if(!(s&64)){this.need=s,this.tree_index=o/3+this.tree[o+2];break}if(s&32){this.mode=Ff;break}return this.mode=fs,e.msg="invalid literal/length code",t=qe,n.bitb=f,n.bitk=h,e.avail_in=d,e.total_in+=_-e.next_in_index,e.next_in_index=_,n.write=c,n.inflate_flush(e,t);case Td:for(a=this.get;h<a;){if(d!=0)t=Be;else return n.bitb=f,n.bitk=h,e.avail_in=d,e.total_in+=_-e.next_in_index,e.next_in_index=_,n.write=c,n.inflate_flush(e,t);d--,f|=(e.next_in[_++]&255)<<h,h+=8}this.len+=f&Yt[a],f>>=a,h-=a,this.need=this.dbits,this.tree=this.dtree,this.tree_index=this.dtree_index,this.mode=kd;case kd:for(a=this.need;h<a;){if(d!=0)t=Be;else return n.bitb=f,n.bitk=h,e.avail_in=d,e.total_in+=_-e.next_in_index,e.next_in_index=_,n.write=c,n.inflate_flush(e,t);d--,f|=(e.next_in[_++]&255)<<h,h+=8}if(o=(this.tree_index+(f&Yt[a]))*3,f>>=this.tree[o+1],h-=this.tree[o+1],s=this.tree[o],s&16){this.get=s&15,this.dist=this.tree[o+2],this.mode=Rd;break}if(!(s&64)){this.need=s,this.tree_index=o/3+this.tree[o+2];break}return this.mode=fs,e.msg="invalid distance code",t=qe,n.bitb=f,n.bitk=h,e.avail_in=d,e.total_in+=_-e.next_in_index,e.next_in_index=_,n.write=c,n.inflate_flush(e,t);case Rd:for(a=this.get;h<a;){if(d!=0)t=Be;else return n.bitb=f,n.bitk=h,e.avail_in=d,e.total_in+=_-e.next_in_index,e.next_in_index=_,n.write=c,n.inflate_flush(e,t);d--,f|=(e.next_in[_++]&255)<<h,h+=8}this.dist+=f&Yt[a],f>>=a,h-=a,this.mode=Nd;case Nd:for(x=c-this.dist;x<0;)x+=n.end;for(;this.len!=0;){if(D==0&&(c==n.end&&n.read!=0&&(c=0,D=c<n.read?n.read-c-1:n.end-c),D==0&&(n.write=c,t=n.inflate_flush(e,t),c=n.write,D=c<n.read?n.read-c-1:n.end-c,c==n.end&&n.read!=0&&(c=0,D=c<n.read?n.read-c-1:n.end-c),D==0)))return n.bitb=f,n.bitk=h,e.avail_in=d,e.total_in+=_-e.next_in_index,e.next_in_index=_,n.write=c,n.inflate_flush(e,t);n.window[c++]=n.window[x++],D--,x==n.end&&(x=0),this.len--}this.mode=os;break;case $d:if(D==0&&(c==n.end&&n.read!=0&&(c=0,D=c<n.read?n.read-c-1:n.end-c),D==0&&(n.write=c,t=n.inflate_flush(e,t),c=n.write,D=c<n.read?n.read-c-1:n.end-c,c==n.end&&n.read!=0&&(c=0,D=c<n.read?n.read-c-1:n.end-c),D==0)))return n.bitb=f,n.bitk=h,e.avail_in=d,e.total_in+=_-e.next_in_index,e.next_in_index=_,n.write=c,n.inflate_flush(e,t);t=Be,n.window[c++]=this.lit,D--,this.mode=os;break;case Ff:if(h>7&&(h-=8,d++,_--),n.write=c,t=n.inflate_flush(e,t),c=n.write,D=c<n.read?n.read-c-1:n.end-c,n.read!=n.write)return n.bitb=f,n.bitk=h,e.avail_in=d,e.total_in+=_-e.next_in_index,e.next_in_index=_,n.write=c,n.inflate_flush(e,t);this.mode=Ld;case Ld:return t=pr,n.bitb=f,n.bitk=h,e.avail_in=d,e.total_in+=_-e.next_in_index,e.next_in_index=_,n.write=c,n.inflate_flush(e,t);case fs:return t=qe,n.bitb=f,n.bitk=h,e.avail_in=d,e.total_in+=_-e.next_in_index,e.next_in_index=_,n.write=c,n.inflate_flush(e,t);default:return t=gn,n.bitb=f,n.bitk=h,e.avail_in=d,e.total_in+=_-e.next_in_index,e.next_in_index=_,n.write=c,n.inflate_flush(e,t)}},Qa.prototype.free=function(n){},Qa.prototype.inflate_fast=function(n,e,t,a,o,s,f,h){var _,d,c,D,x,m,B,F,I,k,U,$,S,L,W,N;B=h.next_in_index,F=h.avail_in,x=f.bitb,m=f.bitk,I=f.write,k=I<f.read?f.read-I-1:f.end-I,U=Yt[n],$=Yt[e];do{for(;m<20;)F--,x|=(h.next_in[B++]&255)<<m,m+=8;if(_=x&U,d=t,c=a,N=(c+_)*3,(D=d[N])==0){x>>=d[N+1],m-=d[N+1],f.window[I++]=d[N+2],k--;continue}do{if(x>>=d[N+1],m-=d[N+1],D&16){for(D&=15,S=d[N+2]+(x&Yt[D]),x>>=D,m-=D;m<15;)F--,x|=(h.next_in[B++]&255)<<m,m+=8;_=x&$,d=o,c=s,N=(c+_)*3,D=d[N];do if(x>>=d[N+1],m-=d[N+1],D&16){for(D&=15;m<D;)F--,x|=(h.next_in[B++]&255)<<m,m+=8;if(L=d[N+2]+(x&Yt[D]),x>>=D,m-=D,k-=S,I>=L)W=I-L,I-W>0&&2>I-W,f.window[I++]=f.window[W++],f.window[I++]=f.window[W++],S-=2;else{W=I-L;do W+=f.end;while(W<0);if(D=f.end-W,S>D){if(S-=D,I-W>0&&D>I-W)do f.window[I++]=f.window[W++];while(--D!=0);else On(f.window,W,f.window,I,D),I+=D,W+=D,D=0;W=0}}do f.window[I++]=f.window[W++];while(--S!=0);break}else if(!(D&64))_+=d[N+2],_+=x&Yt[D],N=(c+_)*3,D=d[N];else return h.msg="invalid distance code",S=h.avail_in-F,S=m>>3<S?m>>3:S,F+=S,B-=S,m-=S<<3,f.bitb=x,f.bitk=m,h.avail_in=F,h.total_in+=B-h.next_in_index,h.next_in_index=B,f.write=I,qe;while(!0);break}if(D&64)return D&32?(S=h.avail_in-F,S=m>>3<S?m>>3:S,F+=S,B-=S,m-=S<<3,f.bitb=x,f.bitk=m,h.avail_in=F,h.total_in+=B-h.next_in_index,h.next_in_index=B,f.write=I,pr):(h.msg="invalid literal/length code",S=h.avail_in-F,S=m>>3<S?m>>3:S,F+=S,B-=S,m-=S<<3,f.bitb=x,f.bitk=m,h.avail_in=F,h.total_in+=B-h.next_in_index,h.next_in_index=B,f.write=I,qe);if(_+=d[N+2],_+=x&Yt[D],N=(c+_)*3,(D=d[N])==0){x>>=d[N+1],m-=d[N+1],f.window[I++]=d[N+2],k--;break}}while(!0)}while(k>=258&&F>=10);return S=h.avail_in-F,S=m>>3<S?m>>3:S,F+=S,B-=S,m-=S<<3,f.bitb=x,f.bitk=m,h.avail_in=F,h.total_in+=B-h.next_in_index,h.next_in_index=B,f.write=I,Be};function Ja(){}Ja.prototype.huft_build=function(n,e,t,a,o,s,f,h,_,d,c){var D,x,m,B,F,I,k,U,$,S,L,W,N,q,H;S=0,F=t;do this.c[n[e+S]]++,S++,F--;while(F!=0);if(this.c[0]==t)return f[0]=-1,h[0]=0,Be;for(U=h[0],I=1;I<=Or&&this.c[I]==0;I++);for(k=I,U<I&&(U=I),F=Or;F!=0&&this.c[F]==0;F--);for(m=F,U>F&&(U=F),h[0]=U,q=1<<I;I<F;I++,q<<=1)if((q-=this.c[I])<0)return qe;if((q-=this.c[F])<0)return qe;for(this.c[F]+=q,this.x[1]=I=0,S=1,N=2;--F!=0;)this.x[N]=I+=this.c[S],N++,S++;F=0,S=0;do(I=n[e+S])!=0&&(this.v[this.x[I]++]=F),S++;while(++F<t);for(t=this.x[m],this.x[0]=F=0,S=0,B=-1,W=-U,this.u[0]=0,L=0,H=0;k<=m;k++)for(D=this.c[k];D--!=0;){for(;k>W+U;){if(B++,W+=U,H=m-W,H=H>U?U:H,(x=1<<(I=k-W))>D+1&&(x-=D+1,N=k,I<H))for(;++I<H&&!((x<<=1)<=this.c[++N]);)x-=this.c[N];if(H=1<<I,this.hn[0]+H>dd)return qe;this.u[B]=L=this.hn[0],this.hn[0]+=H,B!=0?(this.x[B]=F,this.r[0]=I,this.r[1]=U,I=F>>>W-U,this.r[2]=L-this.u[B-1]-I,On(this.r,0,_,(this.u[B-1]+I)*3,3)):f[0]=L}for(this.r[1]=k-W,S>=t?this.r[0]=192:c[S]<a?(this.r[0]=this.v[S]<256?0:96,this.r[2]=this.v[S++]):(this.r[0]=s[this.v[S]-a]+16+64,this.r[2]=o[this.v[S++]-a]),x=1<<k-W,I=F>>>W;I<H;I+=x)On(this.r,0,_,(L+I)*3,3);for(I=1<<k-1;F&I;I>>>=1)F^=I;for(F^=I,$=(1<<W)-1;(F&$)!=this.x[B];)B--,W-=U,$=(1<<W)-1}return q!=0&&m!=1?er:Be},Ja.prototype.inflate_trees_bits=function(n,e,t,a,o){var s;return this.initWorkArea(19),this.hn[0]=0,s=this.huft_build(n,0,19,19,null,null,t,e,a,this.hn,this.v),s==qe?o.msg="oversubscribed dynamic bit lengths tree":(s==er||e[0]==0)&&(o.msg="incomplete dynamic bit lengths tree",s=qe),s},Ja.prototype.inflate_trees_dynamic=function(n,e,t,a,o,s,f,h,_){var d;return this.initWorkArea(288),this.hn[0]=0,d=this.huft_build(t,0,n,257,gm,_m,s,a,h,this.hn,this.v),d!=Be||a[0]==0?(d==qe?_.msg="oversubscribed literal/length tree":d!=pd&&(_.msg="incomplete literal/length tree",d=qe),d):(this.initWorkArea(288),d=this.huft_build(t,n,e,0,vm,wm,f,o,h,this.hn,this.v),d!=Be||o[0]==0&&n>257?(d==qe?_.msg="oversubscribed distance tree":d==er?(_.msg="incomplete distance tree",d=qe):d!=pd&&(_.msg="empty distance tree with lengths",d=qe),d):Be)};function mm(n,e,t,a,o){return n[0]=hm,e[0]=cm,t[0]=dm,a[0]=pm,Be}Ja.prototype.initWorkArea=function(n){this.hn==null&&(this.hn=new Int32Array(1),this.v=new Int32Array(n),this.c=new Int32Array(Or+1),this.r=new Int32Array(3),this.u=new Int32Array(Or),this.x=new Int32Array(Or+1)),this.v.length<n&&(this.v=new Int32Array(n));for(var e=0;e<n;e++)this.v[e]=0;for(var e=0;e<Or+1;e++)this.c[e]=0;for(var e=0;e<3;e++)this.r[e]=0;On(this.c,0,this.u,0,Or),On(this.c,0,this.x,0,Or+1)};var Dm=new Uint8Array(1),ym=typeof Dm.subarray=="function";function On(n,e,t,a,o){if(o!=0){if(n){if(!t)throw"Undef dest"}else throw"Undef src";e==0&&o==n.length?Bf(n,t,a):ym?Bf(n.subarray(e,e+o),t,a):n.BYTES_PER_ELEMENT==1&&o>100?Bf(new Uint8Array(n.buffer,n.byteOffset+e,o),t,a):xm(n,e,t,a,o)}}function xm(n,e,t,a,o){for(var s=0;s<o;++s)t[a+s]=n[e+s]}function Bf(n,e,t){e.set(n,t)}function Em(n,e,t,a){e?t?n=new Uint8Array(n,e,t):n=new Uint8Array(n,e,n.byteLength-e):n=new Uint8Array(n);var o=new ji;o.inflateInit(cd,!0),o.next_in=n,o.next_in_index=0,o.avail_in=n.length;for(var s=[],f=0;;){var h=new Uint8Array(32e3);o.next_out=h,o.next_out_index=0,o.avail_out=h.length;var _=o.inflate(um);if(_!=Be&&_!=pr&&_!=er)throw o.msg;if(o.avail_out!=0){var d=new Uint8Array(h.length-o.avail_out);On(h,0,d,0,h.length-o.avail_out),h=d}if(s.push(h),f+=h.length,_==pr||_==er)break}if(s.length==1)return s[0].buffer;for(var c=new Uint8Array(f),D=0,x=0;x<s.length;++x){var m=s[x];On(m,0,c,D,m.length),D+=m.length}return c.buffer}function Od(){}function Pd(n){n&&(this.id=n)}typeof module<"u"&&(module.exports={DASGroup:Pd,DASFeature:Od});var Cm=2291137574,Am=654086024,Fm=2273964779,Bm=3958540679,Sm=1,Im=2,Tm=3,Md=256,Ud=256*256,Wd=256*256*256,km=256*256*256*256,Rm=new RegExp("^[0-9]+,[0-9]+,[0-9]+");function lt(n,e){var t=n[e]+n[e+1]*Md+n[e+2]*Ud+n[e+3]*Wd+n[e+4]*km;return t}function gr(){}gr.prototype.readChromTree=function(n){var e=this;this.chromsToIDs={},this.idsToChroms={},this.chrAlias={1:"chr1",2:"chr2",3:"chr3",4:"chr4",5:"chr5",6:"chr6",7:"chr7",8:"chr8",9:"chr9",10:"chr10",11:"chr11",12:"chr12",13:"chr13",14:"chr14",15:"chr15",16:"chr16",17:"chr17",18:"chr18",19:"chr19",20:"chr20",21:"chr21",22:"chr22",X:"chrX",Y:"chrY",M:"chrM",MT:"chrM"},this.maxID=0;var t=this.unzoomedDataOffset,a=t-this.chromTreeOffset&3;t=t+4-a,this.data.slice(this.chromTreeOffset,t-this.chromTreeOffset).fetch(function(o){var s=new Uint8Array(o),f=new Int16Array(o),h=new Int32Array(o);h[0],h[1];var _=h[2];h[3],lt(s,16);var d=32,c=function(D){var x=s[D],m=f[D/2+1];D+=4;for(var B=0;B<m;++B)if(x==0){D+=_;var F=lt(s,D);D+=8,F-=e.chromTreeOffset,c(F)}else{for(var I="",k=0;k<_;++k){var U=s[D++];U!=0&&(I+=String.fromCharCode(U))}var $=s[D+3]<<24|s[D+2]<<16|s[D+1]<<8|s[D+0];s[D+7]<<24|s[D+6]<<16|s[D+5]<<8|s[D+4],D+=8,e.chromsToIDs[I]=$,e.idsToChroms[$]=I,e.chrAlias.hasOwnProperty(I)&&(e.chromsToIDs[e.chrAlias[I]]=$,e.idsToChroms[$]=e.chrAlias[I]),e.maxID=Math.max(e.maxID,$)}};c(d),n(e)})};function Mr(n,e,t,a){this.bwg=n,this.cirTreeOffset=e,this.cirTreeLength=t,this.isSummary=a}Mr.prototype.readWigData=function(n,e,t,a){var o=this.bwg.chromsToIDs[n];if(o===void 0)return a([]);this.readWigDataById(o,e,t,a)},Mr.prototype.readWigDataById=function(n,e,t,a){var o=this;if(!this.cirHeader){this.bwg.data.slice(this.cirTreeOffset,48).fetch(function(D){o.cirHeader=D;var x=new Int32Array(o.cirHeader);o.cirBlockSize=x[1],o.readWigDataById(n,e,t,a)});return}var s=[],f=0,h=function(D,x,m,B){return(n<0||D==n)&&x<=t&&m>=e},_=function(D,x){if(o.bwg.instrument&&console.log("level="+x+"; offset="+D+"; time="+(Date.now()|0)),f+=D.length,D.length==1&&D[0]-o.cirTreeOffset==48&&o.cachedCirRoot){c(o.cachedCirRoot,0,x),--f,f==0&&o.fetchFeatures(h,s,a);return}for(var m=4+o.cirBlockSize*32,B,F=0;F<D.length;++F){var I=new Gt(D[F],D[F]+m);B=B?union(B,I):I}for(var k=B.ranges(),U=0;U<k.length;++U){var $=k[U];d(D,$,x)}},d=function(D,x,m,B){x.max()-x.min(),o.bwg.data.slice(x.min(),x.max()-x.min()).fetch(function(F){for(var I=0;I<D.length;++I)x.contains(D[I])&&(c(F,D[I]-x.min(),m),D[I]-o.cirTreeOffset==48&&D[I]-x.min()==0&&(o.cachedCirRoot=F),--f,f==0&&o.fetchFeatures(h,s,a))})},c=function(D,x,m){var B=new Uint8Array(D),F=new Int16Array(D),I=new Int32Array(D),k=B[x],U=F[x/2+1];if(x+=4,k!=0)for(var $=0;$<U;++$){var S=x/4,L=I[S],W=I[S+1],N=I[S+2],q=I[S+3],H=lt(B,x+16),Z=lt(B,x+24);(n<0||L<n||L==n&&W<=t)&&(n<0||N>n||N==n&&q>=e)&&s.push({offset:H,size:Z}),x+=32}else{for(var Y=[],$=0;$<U;++$){var S=x/4,L=I[S],W=I[S+1],N=I[S+2],q=I[S+3],H=lt(B,x+16);(n<0||L<n||L==n&&W<=t)&&(n<0||N>n||N==n&&q>=e)&&Y.push(H),x+=24}Y.length>0&&_(Y,m+1)}};_([o.cirTreeOffset+48],1)},Mr.prototype.fetchFeatures=function(n,e,t){var a=this;if(e.sort(function(h,_){return(h.offset|0)-(_.offset|0)}),e.length==0)t([]);else{var o=[],s=function(h,_,d,c){c||(c={});var D=new Od;D._chromId=h,D.segment=a.bwg.idsToChroms[h],D.min=_,D.max=d,D.type=a.bwg.type;for(var x in c)D[x]=c[x];o.push(D)},f=function(){if(e.length==0){t(o);return}else{var h=e[0];if(h.data)a.parseFeatures(h.data,s,n),e.splice(0,1),f();else{for(var _=h.offset,d=h.size,c=1;c<e.length&&e[c].offset==_+d;)d+=e[c].size,++c;a.bwg.data.slice(_,d).fetch(function(D){for(var x=0,m=0;x<d;){var B=e[m],F;if(a.bwg.uncompressBufSize>0)F=Em(D,x+2,B.size-2);else{var I=new Uint8Array(B.size);arrayCopy(new Uint8Array(D,x,B.size),0,I,0,B.size),F=I.buffer}B.data=F,x+=B.size,++m}f()})}}};f()}},Mr.prototype.parseFeatures=function(n,e,t){var a=new Uint8Array(n);if(this.isSummary)for(var o=new Int16Array(n),s=new Int32Array(n),f=new Float32Array(n),h=n.byteLength/32,_=0;_<h;++_){var d=s[_*8],c=s[_*8+1],D=s[_*8+2],x=s[_*8+3];f[_*8+4];var m=f[_*8+5],B=f[_*8+6];if(f[_*8+7],t(d,c+1,D)){var F={type:"bigwig",score:B/x,maxScore:m};this.bwg.type=="bigbed"&&(F.type="density"),e(d,c+1,D,F)}}else if(this.bwg.type=="bigwig"){var o=new Int16Array(n),s=new Int32Array(n),f=new Float32Array(n),d=s[0],I=s[1];s[2];var k=s[3],U=s[4],$=a[20],h=o[11];if($==Tm)for(var _=0;_<h;++_){var S=f[_+6],L=I+_*k+1,W=I+_*k+U;t(d,L,W)&&e(d,L,W,{score:S})}else if($==Im)for(var _=0;_<h;++_){var c=s[_*2+6]+1,D=c+U-1,S=f[_*2+7];t(d,c,D)&&e(d,c,D,{score:S})}else if($==Sm)for(var _=0;_<h;++_){var c=s[_*3+6]+1,D=s[_*3+7],S=f[_*3+8];c>D&&(c=D),t(d,c,D)&&e(d,c,D,{score:S})}else console.log("Currently not handling bwgType="+$)}else if(this.bwg.type=="bigbed")for(var N=0,q=this.bwg.definedFieldCount,H=this.bwg.schema;N<a.length;){var d=a[N+3]<<24|a[N+2]<<16|a[N+1]<<8|a[N+0],c=a[N+7]<<24|a[N+6]<<16|a[N+5]<<8|a[N+4],D=a[N+11]<<24|a[N+10]<<16|a[N+9]<<8|a[N+8];N+=12;for(var Z="";;){var Y=a[N++];if(Y!=0)Z+=String.fromCharCode(Y);else break}var re={},se;if(Z.length>0?se=Z.split("	"):se=[],se.length>0&&q>3&&(re.label=se[0]),se.length>1&&q>4){var S=parseInt(se[1]);isNaN(S)||(re.score=S)}if(se.length>2&&q>5&&(re.orientation=se[2]),se.length>5&&q>8){var fe=se[5];Rm.test(fe)&&(re.itemRgb="rgb("+fe+")")}if(se.length>q-3&&H)for(var ce=q-3;ce<se.length;++ce)re[H.fields[ce+3].name]=se[ce];if(t(d,c+1,D,se))if(q<12)e(d,c+1,D,re);else{var Me=se[3]|0,Fe=se[4]|0,Ce=se[6]|0,vn=se[7].split(","),kt=se[8].split(",");if(re.exonFrames){var tt=re.exonFrames.split(",");re.exonFrames=void 0}re.type="transcript";var Te=new Pd;for(var Pn in re)Te[Pn]=re[Pn];if(Te.id=se[0],Te.segment=this.bwg.idsToChroms[d],Te.min=c+1,Te.max=D,Te.notes=[],re.groups=[Te],se.length>9){var Oe=re.geneName||se[9],ke=Oe;se.length>10&&(ke=se[10]),re.geneName2&&(ke=re.geneName2);var Dt=shallowCopy(Te);Dt.id=Oe,Dt.label=ke,Dt.type="gene",re.groups.push(Dt)}for(var Qt=[],Rt=0;Rt<Ce;++Rt){var wn=(kt[Rt]|0)+c,vr=wn+(vn[Rt]|0),yt=new Gt(wn,vr);Qt.push(yt)}for(var Nt=union(Qt),bn=Nt.ranges(),Je=0;Je<bn.length;++Je){var _t=bn[Je];e(d,_t.min()+1,_t.max(),re)}if(Fe>Me){var tr=re.orientation=="+"?new Gt(Me,Fe+3):new Gt(Me-3,Fe),vt=intersection(Nt,tr);if(vt){re.type="translation";for(var wr=vt.ranges(),bi=0,Jt=0;wr[0].min()>bn[Jt].max();)Jt++;for(var Je=0;Je<wr.length;++Je){var xt=Je;re.orientation=="-"&&(xt=wr.length-Je-1);var _t=wr[xt];if(re.readframe=bi,tt){var mn=parseInt(tt[xt+Jt]);typeof mn=="number"&&mn>=0&&mn<=2&&(re.readframe=mn,re.readframeExplicit=!0)}var br=_t.max()-_t.min();bi=(bi+br)%3,e(d,_t.min()+1,_t.max(),re)}}}}}else throw Error("Don't know what to do with "+this.bwg.type)},Mr.prototype.getFirstAdjacent=function(n,e,t,a){var o=this.bwg.chromsToIDs[n];if(o===void 0)return a([]);this.getFirstAdjacentById(o,e,t,a)},Mr.prototype.getFirstAdjacentById=function(n,e,t,a){var o=this;if(!this.cirHeader){this.bwg.data.slice(this.cirTreeOffset,48).fetch(function(x){o.cirHeader=x;var m=new Int32Array(o.cirHeader);o.cirBlockSize=m[1],o.getFirstAdjacentById(n,e,t,a)});return}var s=null,f=-1,h=-1,_=0,d=function(x,m){_+=x.length;for(var B=4+o.cirBlockSize*32,F,I=0;I<x.length;++I){var k=new Gt(x[I],x[I]+B);F=F?union(F,k):k}for(var U=F.ranges(),$=0;$<U.length;++$){var S=U[$];c(x,S)}},c=function(x,m,B,F){m.max()-m.min(),o.bwg.data.slice(m.min(),m.max()-m.min()).fetch(function(I){for(var k=0;k<x.length;++k)if(m.contains(x[k])&&(D(I,x[k]-m.min()),--_,_==0)){if(!s)return t>0&&(n!=0||e>0)?o.getFirstAdjacentById(0,0,t,a):t<0&&(n!=o.bwg.maxID||e<1e9)?o.getFirstAdjacentById(o.bwg.maxID,1e9,t,a):a([]);o.fetchFeatures(function(U,$,S,L){return t<0&&(U<n||S<e)||t>0&&(U>n||$>e)},[s],function(U){for(var $=null,S=-1,L=-1,W=0;W<U.length;++W){var N=U[W],q=N._chromId,H=N.min,Z=N.max;($==null||t<0&&(q>S||Z>L)||t>0&&(q<S||H<L))&&($=N,L=t<0?Z:H,S=q)}return $!=null?a([$]):a([])})}})},D=function(x,m,B){var F=new Uint8Array(x),I=new Int16Array(x),k=new Int32Array(x),U=F[m],$=I[m/2+1];if(m+=4,U!=0)for(var S=0;S<$;++S){var L=m/4,W=k[L],N=k[L+1],q=k[L+2],H=k[L+3],Z=lt(F,m+16),Y=lt(F,m+24);(t<0&&(W<n||W==n&&N<=e)||t>0&&(q>n||q==n&&H>=e))&&(/_random/.exec(o.bwg.idsToChroms[W])||(s==null||t<0&&(q>f||q==f&&H>h)||t>0&&(W<f||W==f&&N<h))&&(s={offset:Z,size:Y},h=t<0?H:N,f=t<0?q:W)),m+=32}else{for(var re=-1,se=-1,S=0;S<$;++S){var L=m/4,W=k[L],N=k[L+1],q=k[L+2],H=k[L+3],Z=k[L+4]<<32|k[L+5];(t<0&&(W<n||W==n&&N<=e)&&q>=n||t>0&&(q>n||q==n&&H>=e)&&W<=n)&&(re<0||H>se)&&(re=Z,se=t<0?H:N),m+=24}re>=0&&d([re])}};d([o.cirTreeOffset+48])},gr.prototype.readWigData=function(n,e,t,a){this.getUnzoomedView().readWigData(n,e,t,a)},gr.prototype.getUnzoomedView=function(){if(!this.unzoomedView){var n=4e3,e=this.zoomLevels[0];e&&(n=this.zoomLevels[0].dataOffset-this.unzoomedIndexOffset),this.unzoomedView=new Mr(this,this.unzoomedIndexOffset,n,!1)}return this.unzoomedView},gr.prototype.getZoomedView=function(n){var e=this.zoomLevels[n];return e.view||(e.view=new Mr(this,e.indexOffset,4e3,!0)),e.view};function Nm(n,e,t){var a=new gr;a.data=n,a.name=t,a.data.slice(0,512).salted().fetch(function(o){if(!o)return e(null,"Couldn't fetch file");var s=o,f=new Uint8Array(s),h=new Int16Array(s),_=new Int32Array(s),d=f[0]+Md*f[1]+Ud*f[2]+Wd*f[3];if(d==Cm)a.type="bigwig";else if(d==Fm)a.type="bigbed";else return d==Am||d==Bm?e(null,"Currently don't support big-endian BBI files"):e(null,"Not a supported format, magic=0x"+d.toString(16));a.version=h[2],a.numZoomLevels=h[3],a.chromTreeOffset=lt(f,8),a.unzoomedDataOffset=lt(f,16),a.unzoomedIndexOffset=lt(f,24),a.fieldCount=h[16],a.definedFieldCount=h[17],a.asOffset=lt(f,36),a.totalSummaryOffset=lt(f,44),a.uncompressBufSize=_[13],a.extHeaderOffset=lt(f,56),a.zoomLevels=[];for(var c=0;c<a.numZoomLevels;++c){var D=_[c*6+16],x=lt(f,c*24+72),m=lt(f,c*24+80);a.zoomLevels.push({reduction:D,dataOffset:x,indexOffset:m})}a.readChromTree(function(){a.getAutoSQL(function(B){return a.schema=B,e(a)})})},{timeout:5e3})}gr.prototype._tsFetch=function(n,e,t,a,o){var s=this;if(n>=this.zoomLevels.length-1)if(!this.topLevelReductionCache)this.getZoomedView(this.zoomLevels.length-1).readWigDataById(-1,0,3e8,function(c){return s.topLevelReductionCache=c,s._tsFetch(n,e,t,a,o)});else{for(var f=[],h=this.topLevelReductionCache,_=0;_<h.length;++_)h[_]._chromId==e&&f.push(h[_]);return o(f)}else{var d;return n<0?d=this.getUnzoomedView():d=this.getZoomedView(n),d.readWigDataById(e,t,a,o)}},gr.prototype.thresholdSearch=function(n,e,t,a,o){t=t<0?-1:1;for(var s=this,f=this.chromsToIDs[n],h=[{chrOrd:0,chr:f,zoom:s.zoomLevels.length-4,min:0,max:3e8,fromRef:!0}],_=1;_<=this.maxID+1;++_){var d=(f+t*_)%(this.maxID+1);d<0&&(d+=this.maxID+1),h.push({chrOrd:_,chr:d,zoom:s.zoomLevels.length-1,min:0,max:3e8})}function c(){if(h.length==0)return o(null);h.sort(function(x,m){var B=x.zoom-m.zoom;return B!=0||(B=x.chrOrd-m.chrOrd,B!=0)?B:x.min-m.min*t});var D=h.splice(0,1)[0];s._tsFetch(D.zoom,D.chr,D.min,D.max,function(x){var m=t>0?0:3e8;D.fromRef&&(m=e);for(var B=0;B<x.length;++B){var F=x[B],I;if(F.maxScore!=null?I=F.maxScore:I=F.score,t>0){if(I>a)if(D.zoom<0){if(F.min>m)return o(F)}else F.max>m&&h.push({chr:D.chr,chrOrd:D.chrOrd,zoom:D.zoom-2,min:F.min,max:F.max,fromRef:D.fromRef})}else if(I>a)if(D.zoom<0){if(F.max<m)return o(F)}else F.min<m&&h.push({chr:D.chr,chrOrd:D.chrOrd,zoom:D.zoom-2,min:F.min,max:F.max,fromRef:D.fromRef})}c()})}c()},gr.prototype.getAutoSQL=function(n){if(!this.asOffset)return n(null);this.data.slice(this.asOffset,2048).fetch(function(e){for(var t=new Uint8Array(e),a="",o=0;o<t.length&&t[o]!=0;++o)a+=String.fromCharCode(t[o]);var s=/(\w+)\s+(\w+)\s+("([^"]+)")?\s+\(\s*/,f=/([\w\[\]]+)\s+(\w+)\s*;\s*("([^"]+)")?\s*/g,h=s.exec(a);if(h){var _={declType:h[1],name:h[2],comment:h[4],fields:[]};a=a.substring(h[0]);for(var d=f.exec(a);d!=null;d=f.exec(a))_.fields.push({type:d[1],name:d[2],comment:d[4]});return n(_)}})},gr.prototype.getExtraIndices=function(n){var e=this;if(this.version<4||this.extHeaderOffset==0||this.type!="bigbed")return n(null);this.data.slice(this.extHeaderOffset,64).fetch(function(t){if(!t)return n(null,"Couldn't fetch extension header");var a=new Uint8Array(t),o=new Int16Array(t);o[0];var s=o[1],f=lt(a,4);if(s==0)return n(null);e.data.slice(f,s*20).fetch(function(h){if(!h)return n(null,"Couldn't fetch index info");for(var _=new Uint8Array(h),d=new Int16Array(h),c=[],D=0;D<s;++D){var x=d[D*10],m=d[D*10+1],B=lt(_,D*20+4),F=d[D*10+8],I=new Gd(e,x,m,B,F);c.push(I)}n(c)})})};function Gd(n,e,t,a,o){this.bbi=n,this.type=e,this.fieldCount=t,this.offset=a,this.field=o}Gd.prototype.lookup=function(n,e){var t=this;this.bbi.data.slice(this.offset,32).fetch(function(a){var o=new Uint8Array(a),s=new Int32Array(a);s[0];var f=s[1],h=s[2],_=s[3];lt(o,16);var d=32;function c(D){t.bbi.data.slice(D,4+f*(h+_)).fetch(function(x){var m=new Uint8Array(x),B=new Uint16Array(x),F=m[0],I=B[1],k=4;if(F==0){for(var U=null,$=0;$<I;++$){for(var S="",L=0;L<h;++L){var W=m[k++];W!=0&&(S+=String.fromCharCode(W))}var N=lt(m,k);if(k+=8,n.localeCompare(S)<0&&U){c(U);return}U=N}c(U)}else{for(var $=0;$<I;++$){for(var S="",L=0;L<h;++L){var W=m[k++];W!=0&&(S+=String.fromCharCode(W))}if(S==n){var q=lt(m,k),H=readInt(m,k+8);return t.bbi.getUnzoomedView().fetchFeatures(function(re,se,fe,ce){if(ce&&ce.length>t.field-3)return ce[t.field-3]==n},[{offset:q,size:H}],e)}k+=_}return e([])}})}c(t.offset+d)})};var $m="";function Lm(n){return Om(qd(Hd(n)))}function Sf(n){return Pm(qd(Hd(n)))}function qd(n){return Um(Wm(Mm(n),n.length*8))}function Om(n){for(var e="0123456789abcdef",t="",a,o=0;o<n.length;o++)a=n.charCodeAt(o),t+=e.charAt(a>>>4&15)+e.charAt(a&15);return t}function Pm(n){for(var e="ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/",t="",a=n.length,o=0;o<a;o+=3)for(var s=n.charCodeAt(o)<<16|(o+1<a?n.charCodeAt(o+1)<<8:0)|(o+2<a?n.charCodeAt(o+2):0),f=0;f<4;f++)o*8+f*6>n.length*8?t+=$m:t+=e.charAt(s>>>6*(3-f)&63);return t}function Hd(n){for(var e="",t=-1,a,o;++t<n.length;)a=n.charCodeAt(t),o=t+1<n.length?n.charCodeAt(t+1):0,55296<=a&&a<=56319&&56320<=o&&o<=57343&&(a=65536+((a&1023)<<10)+(o&1023),t++),a<=127?e+=String.fromCharCode(a):a<=2047?e+=String.fromCharCode(192|a>>>6&31,128|a&63):a<=65535?e+=String.fromCharCode(224|a>>>12&15,128|a>>>6&63,128|a&63):a<=2097151&&(e+=String.fromCharCode(240|a>>>18&7,128|a>>>12&63,128|a>>>6&63,128|a&63));return e}function Mm(n){for(var e=Array(n.length>>2),t=0;t<e.length;t++)e[t]=0;for(var t=0;t<n.length*8;t+=8)e[t>>5]|=(n.charCodeAt(t/8)&255)<<24-t%32;return e}function Um(n){for(var e="",t=0;t<n.length*32;t+=8)e+=String.fromCharCode(n[t>>5]>>>24-t%32&255);return e}function Wm(n,e){n[e>>5]|=128<<24-e%32,n[(e+64>>9<<4)+15]=e;for(var t=Array(80),a=1732584193,o=-271733879,s=-1732584194,f=271733878,h=-1009589776,_=0;_<n.length;_+=16){for(var d=a,c=o,D=s,x=f,m=h,B=0;B<80;B++){B<16?t[B]=n[_+B]:t[B]=If(t[B-3]^t[B-8]^t[B-14]^t[B-16],1);var F=_r(_r(If(a,5),Gm(B,o,s,f)),_r(_r(h,t[B]),qm(B)));h=f,f=s,s=If(o,30),o=a,a=F}a=_r(a,d),o=_r(o,c),s=_r(s,D),f=_r(f,x),h=_r(h,m)}return Array(a,o,s,f,h)}function Gm(n,e,t,a){return n<20?e&t|~e&a:n<40?e^t^a:n<60?e&t|e&a|t&a:e^t^a}function qm(n){return n<20?1518500249:n<40?1859775393:n<60?-1894007588:-899497514}function _r(n,e){var t=(n&65535)+(e&65535),a=(n>>16)+(e>>16)+(t>>16);return a<<16|t&65535}function If(n,e){return n<<e|n>>>32-e}typeof module<"u"&&(module.exports={b64_sha1:Sf,hex_sha1:Lm});function Hm(n){var e={};for(var t in n)e[t]=n[t];return e}function wi(n,e,t,a){a||(typeof e=="object"?(a=e,e=void 0):a={}),this.url=n,this.start=e||0,t&&(this.end=t),this.opts=a}wi.prototype.slice=function(n,e){if(n<0)throw"Bad slice "+n;var t=this.start,a=this.end;return t&&n?t=t+n:t=n||t,e&&t?a=t+e-1:a=a||e-1,new wi(this.url,t,a,this.opts)};var Vd=0,Zd=navigator.userAgent.indexOf("Safari")>=0&&navigator.userAgent.indexOf("Chrome")<0;wi.prototype.fetchAsText=function(n){try{var e=new XMLHttpRequest,t,a=this.url;if((Zd||this.opts.salt)&&a.indexOf("?")<0&&(a=a+"?salt="+Sf(""+Date.now()+","+ ++Vd)),e.open("GET",a,!0),this.end){if(this.end-this.start>1e8)throw"Monster fetch!";e.setRequestHeader("Range","bytes="+this.start+"-"+this.end),e.setRequestHeader("accept-encoding","gzip,deflate"),t=this.end-this.start+1}e.onreadystatechange=function(){if(e.readyState==4)return e.status==200||e.status==206?n(e.responseText):n(null)},this.opts.credentials&&(e.withCredentials=!0),e.send("")}catch{return n(null)}},wi.prototype.salted=function(){var n=Hm(this.opts);return n.salt=!0,new wi(this.url,this.start,this.end,n)},wi.prototype.fetch=function(n,e){var t=this;e=e||{};var a=e.attempt||1,o=e.truncatedLength;if(a>3)return n(null);try{var s,f=new XMLHttpRequest,h,_=this.url;if((Zd||this.opts.salt)&&_.indexOf("?")<0&&(_=_+"?salt="+Sf(""+Date.now()+","+ ++Vd)),f.open("GET",_,!0),f.overrideMimeType("text/plain; charset=x-user-defined"),this.end){if(this.end-this.start>1e8)throw"Monster fetch!";f.setRequestHeader("Range","bytes="+this.start+"-"+this.end),h=this.end-this.start+1}f.responseType="arraybuffer",f.onreadystatechange=function(){if(f.readyState==4)if(s&&clearTimeout(s),f.status==200||f.status==206)if(f.response){var d=f.response.byteLength;return h&&h!=d&&(!o||d!=o)?t.fetch(n,{attempt:a+1,truncatedLength:d}):n(f.response)}else{if(f.mozResponseArrayBuffer)return n(f.mozResponseArrayBuffer);var c=f.responseText;return h&&h!=c.length&&(!o||c.length!=o)?t.fetch(n,{attempt:a+1,truncatedLength:c.length}):n(Vm(f.responseText))}else return t.fetch(n,{attempt:a+1})},this.opts.credentials&&f.setRequestHeader("Authorization",this.opts.credentials),f.send("")}catch{return n(null)}};function Vm(n){if(!n)return null;for(var e=new Uint8Array(n.length),t=0;t<e.length;++t)e[t]=n.charCodeAt(t);return e.buffer}/**
- * Reads and gets data from bigwig or bigbed files hosted remotely.  Gets DASFeature records, which vary in schema
- * depending on the file.
- *
- * @license MIT
- */class Zm{constructor(e){ue(this,"url");ue(this,"bigWigPromise");this.url=e,this.bigWigPromise=this.loadBigWig(e)}async loadBigWig(e){try{return new Promise((t,a)=>{Nm(new wi(e),(o,s)=>{s?a(s):t(o)})})}catch(t){return console.error("Failed to dynamically load the BigWig module:",t),Promise.reject(t)}}async getData(e,t,a){const o=await this.bigWigPromise,s=a.zoomLevel===void 0||a.zoomLevel===zb.AUTO?this._getMatchingZoomLevel(o,t):Number.parseInt(a.zoomLevel);let f=e.map(d=>this._getDataForChromosome(d,o,s));const h=await Promise.all(f),_=Xt.flatten(h);for(let d of _)d.min-=1;return _}_getMatchingZoomLevel(e,t){if(!t)return-1;if(e.zoomLevels.length===1)return 0;let o=e.zoomLevels.slice().sort((s,f)=>f.reduction-s.reduction).find(s=>s.reduction<t);return e.zoomLevels.findIndex(s=>s===o)}_getDataForChromosome(e,t,a){const o=e.start+1,s=e.end;return new Promise((f,h)=>{try{a===-1?t.readWigData(e.chr,o,s,f):t.getZoomedView(a).readWigData(e.chr,o,s,f)}catch(_){h(_)}})}}let Ur={};const Tf={WashU:"https://lambda.epigenomegateway.org/v3"},Xm={geneannotation:async function(e){let t,a;const o=e.trackModel;o.apiConfig&&o.apiConfig.genome?t=o.apiConfig.genome:t=e.genomeName,o.apiConfig&&o.apiConfig.format in Tf?a=Tf[`${o.apiConfig.format}`]:a=Tf.WashU;let s=`${a}/${t}/genes/${e.name}/queryRegion?chr=${e.chr}&start=${e.start}&end=${e.end}`;return(await fetch(s,{method:"GET"})).json()},snp:async function(e){const t={hg19:"https://grch37.rest.ensembl.org/overlap/region/human",hg38:"https://rest.ensembl.org/overlap/region/human"},a=e.genomeName in t?t[`${e.genomeName}`]:null;if(!a)return[];const o={"Content-Type":"application/json"};if(e.end-e.start<=3e4){const s=`${a}/${e.chr.substr(3)}:${e.start}-${e.end+"?content-type=application%2Fjson&feature=variation"}`;return fetch(s,{headers:o}).then(f=>{if(!f.ok)throw new Error("Network response was not ok");return f.json()}).catch(f=>(console.error("There was a problem with the fetch operation:",f),{data:[]}))}else return[]},bed:async function(e){return st(e,"bedOrTabix")},bedcolor:async function(e){return st(e,"bedOrTabix")},omeroidr:async function(e){return st(e,"bedOrTabix")},bedgraph:async function(e){return st(e,"bedOrTabix")},qbed:async function(e){return st(e,"bedOrTabix")},dbedgraph:async function(e){return st(e,"bedOrTabix")},boxplot:async function(e){return st(e,"big")},modbed:async function(e){return st(e,"bedOrTabix")},jaspar:async function(e){return st(e,"jaspar")},bigbed:async function(e){return st(e,"bigbed")},refbed:async function(e){return st(e,"bedOrTabix")},matplot:async function(e){return st(e,"bedOrTabix")},bigwig:async function(e){return st(e,"big")},categorical:async function(e){return st(e,"bedOrTabix")},longrange:async function(e){return st(e,"bedOrTabix")},dynseq:async function(e){return st(e,"big")},repeatmasker:async function(e){return st(e,"repeat")},biginteract:async function(e){return st(e,"big")},methylc:async function(e){return st(e,"bedOrTabix")},genomealign:function(e){return st(e,"bedOrTabix")},vcf:function(e){return st(e,"vcf")}};function st(n,e){let t=null;n.trackModel.indexUrl&&(t=n.trackModel.indexUrl),n.trackModel.id in Ur||(e==="bedOrTabix"?Ur[`${n.trackModel.id}`]=new Jv(n.trackModel.url,t):e==="vcf"?Ur[`${n.trackModel.id}`]=new jb(n.trackModel.url,t):e==="bigbed"?Ur[`${n.trackModel.id}`]=new Zm(n.trackModel.url):e==="big"?Ur[`${n.trackModel.id}`]=new Ef(n.trackModel.url):e==="repeat"?Ur[`${n.trackModel.id}`]=new Zb(n.trackModel.url):e==="jaspar"&&(Ur[`${n.trackModel.id}`]=new Kb(n.trackModel.url)));let a=Ur[`${n.trackModel.id}`];return e in{repeat:"",jaspar:"",bigbed:""}?a.getData(n.nav,n.basesPerPixel,n.trackModel.options):a.getData(n.nav,n.trackModel.options)}async function Km(n){const e=n.regionExpandLoci,t=n.trackToFetch,a=n.genomicLoci,o={},s={},f={},h=n.useFineModeNav,_=n.primaryGenName,d=n.initGenomicLoci;f[`${_}`]={genomicLoci:a,regionExpandLoci:e,initGenomicLoci:d};const c=t,D=[e];c.length>0&&await x(n.visData.visRegion,c);async function x(B,F){let I=[];for(let Z of n.visData.visRegion._navContext._features){let Y=new rt(Z.locus.chr,Z.locus.start,Z.locus.end);I.push(new qn(Z.name,Y))}let k=new In(n.visData.visRegion._navContext._name,I),U=new Ti(k,B._startBase,B._endBase),$=[];for(let Z of n.visData.viewWindowRegion._navContext._features){let Y=new rt(Z.locus.chr,Z.locus.start,Z.locus.end);$.push(new qn(Z.name,Y))}let S=new In(n.visData.viewWindowRegion._navContext._name,$),L=new Ti(S,n.visData.viewWindowRegion._startBase,n.visData.viewWindowRegion._endBase),W={visWidth:n.visData.visWidth,visRegion:U,viewWindow:new Ne(n.windowWidth,n.windowWidth*2),viewWindowRegion:L};await Promise.all(F.map(async(Z,Y)=>{let re;await Promise.all(D.map(async(se,fe)=>{try{const ce=await Xm.genomealign({nav:se,options:{height:40,isCombineStrands:!1,colorsForContext:{CG:{color:"rgb(100,139,216)",background:"#d9d9d9"},CHG:{color:"rgb(255,148,77)",background:"#ffe0cc"},CHH:{color:"rgb(255,0,255)",background:"#ffe5ff"}},depthColor:"#525252",depthFilter:0,maxMethyl:1,label:""},url:Z.url,trackModel:Z});let Me=[];for(const Fe of ce){let Ce=Bg.parse("{"+Fe[3]+"}");Fe[3]=Ce,Me.push(new Rg(Fe))}re=Me,s[`${Z.id}`]=""}catch{re={error:`Error processing genome align track with id ${Z.id}: Error`}}})),o[`${Z.id}`]={name:Z.name,records:re,query:Z.querygenome,id:Z.id,trackModel:Z,metadata:Z.metadata,isBigChain:!1}}));let N=[];for(const Z in o)"error"in o[Z].records||N.push(o[Z]);let H=new k_(n.primaryGenName).multiAlign(W,N);for(let Z in H){let Y;if(!h){Y=[].concat.apply([],H[`${Z}`].drawData.map(Te=>Te.segments));const fe=Y.map(Te=>Te.record.queryStrand),ce=Y.map(Te=>Te.targetXSpan),Me=Y.map(Te=>Te.queryXSpan),Fe=Y.map(Te=>Te.visiblePart.getLocus().toString()),Ce=Y.map(Te=>Te.visiblePart.getQueryLocus().toString()),vn=Y.map(Te=>Ni(Te.visiblePart.getLength())),kt=Y.map(Te=>Ni(Te.visiblePart.getQueryLocus().getLength()));let tt={};tt={strandList:fe,targetXSpanList:ce,queryXSpanList:Me,targetLocusList:Fe,queryLocusList:Ce,lengthList:vn,queryLengthList:kt},H[`${Z}`]={...H[`${Z}`],...tt}}for(let fe=0;fe<H[`${Z}`].drawData.length;fe++){let ce=H[`${Z}`].drawData[fe],Me={};const{targetXSpan:Fe}=ce;if(h){const Ce=ce.visiblePart.getTargetSequence(),vn=ce.visiblePart.getQuerySequence(),kt=Fe.getLength()/Ce.length,tt=ce.visiblePart.getLocus().toString(),Te=ce.visiblePart.getQueryLocus().toString(),Pn=ce.visiblePart.getQueryLocusFine(),Oe=ce.targetSegments.filter(Qt=>!Qt.isGap),ke=ce.querySegments.filter(Qt=>!Qt.isGap),Dt=ce.record.getIsReverseStrandQuery();Me={targetSequence:Ce,querySequence:vn,nonGapsQuery:ke,baseWidth:kt,targetLocus:tt,queryLocus:Te,nonGapsTarget:Oe,isReverseStrandQuery:Dt,queryLocusFine:Pn}}else Me={estimatedLabelWidth:ce.queryFeature.toString().length};H[`${Z}`].drawData[fe]={...ce,...Me}}let re=[],se=H[`${Z}`].queryRegion._navContext._featuresForChr;for(let fe in se)if(fe!==""){let ce=m(se[`${fe}`][0].name).start,Me=m(se[`${fe}`][se[`${fe}`].length-1].name).end;re.push({chr:fe,start:ce,end:Me})}f[`${_}`].primaryVisData=H[`${Z}`].primaryVisData,f[`${Z}`]={queryGenomicCoord:new Array(re),id:H[`${Z}`].id,queryRegion:H[`${Z}`].queryRegion},o[`${H[`${Z}`].id}`].records=H[`${Z}`]}}function m(B){const[F,I]=B.split(":"),[k,U]=I.split("-"),$=F.slice(3),S=parseInt(k,10),L=parseInt(U,10);return{chr:$,start:S,end:L}}return{fetchResults:o,navData:{...n,genomicFetchCoord:f,trackToDrawId:s,regionSetStartBp:n.visData.visRegion._endBase-n.visData.visRegion._startBase===n.bpRegionSize?0:null}}}typeof self<"u"&&"postMessage"in self&&"onmessage"in self&&typeof window>"u"&&(self.onmessage=async n=>{try{const e=await Km(n.data);postMessage(e)}catch(e){console.error("Worker error:",e),postMessage({error:e instanceof Error?e.message:"Unknown error"})}})})();