wgts-report 0.1.3 → 0.1.4
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/dist/assets/wgts-report.js +50 -50
- package/dist/index.html +2 -2
- package/package.json +1 -1
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var Tv=l=>{throw TypeError(l)};var Qf=(l,i,s)=>i.has(l)||Tv("Cannot "+s);var M=(l,i,s)=>(Qf(l,i,"read from private field"),s?s.call(l):i.get(l)),ue=(l,i,s)=>i.has(l)?Tv("Cannot add the same private member more than once"):i instanceof WeakSet?i.add(l):i.set(l,s),K=(l,i,s,u)=>(Qf(l,i,"write to private field"),u?u.call(l,s):i.set(l,s),s),_e=(l,i,s)=>(Qf(l,i,"access private method"),s);var Qo=(l,i,s,u)=>({set _(c){K(l,i,c,s)},get _(){return M(l,i,u)}});function Ix(l,i){for(var s=0;s<i.length;s++){const u=i[s];if(typeof u!="string"&&!Array.isArray(u)){for(const c in u)if(c!=="default"&&!(c in l)){const f=Object.getOwnPropertyDescriptor(u,c);f&&Object.defineProperty(l,c,f.get?f:{enumerable:!0,get:()=>u[c]})}}}return Object.freeze(Object.defineProperty(l,Symbol.toStringTag,{value:"Module"}))}(function(){const i=document.createElement("link").relList;if(i&&i.supports&&i.supports("modulepreload"))return;for(const c of document.querySelectorAll('link[rel="modulepreload"]'))u(c);new MutationObserver(c=>{for(const f of c)if(f.type==="childList")for(const g of f.addedNodes)g.tagName==="LINK"&&g.rel==="modulepreload"&&u(g)}).observe(document,{childList:!0,subtree:!0});function s(c){const f={};return c.integrity&&(f.integrity=c.integrity),c.referrerPolicy&&(f.referrerPolicy=c.referrerPolicy),c.crossOrigin==="use-credentials"?f.credentials="include":c.crossOrigin==="anonymous"?f.credentials="omit":f.credentials="same-origin",f}function u(c){if(c.ep)return;c.ep=!0;const f=s(c);fetch(c.href,f)}})();function Jx(l){return l&&l.__esModule&&Object.prototype.hasOwnProperty.call(l,"default")?l.default:l}var Yf={exports:{}},Is={};/**
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*/var Mv;function Px(){if(Mv)return Is;Mv=1;var l=Symbol.for("react.transitional.element"),i=Symbol.for("react.fragment");function s(u,c,f){var g=null;if(f!==void 0&&(g=""+f),c.key!==void 0&&(g=""+c.key),"key"in c){f={};for(var m in c)m!=="key"&&(f[m]=c[m])}else f=c;return c=f.ref,{$$typeof:l,type:u,key:g,ref:c!==void 0?c:null,props:f}}return Is.Fragment=i,Is.jsx=s,Is.jsxs=s,Is}var jv;function Wx(){return jv||(jv=1,Yf.exports=Px()),Yf.exports}var d=Wx(),Xf={exports:{}},he={};/**
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@@ -38,15 +38,15 @@ var Nv=l=>{throw TypeError(l)};var Qf=(l,i,s)=>i.has(l)||Nv("Cannot "+s);var M=(
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if(e.child!==null){e.child.return=e,e=e.child;continue}if(e===t)break e;for(;e.sibling===null;){if(e.return===null||e.return===t)break e;e=e.return}e.sibling.return=e.return,e=e.sibling}switch(o){case"backwards":n=Om(t.child),n===null?(o=t.child,t.child=null):(o=n.sibling,n.sibling=null,Uc(t)),ro(t,!0,o,null,r,a);break;case"unstable_legacy-backwards":for(n=null,o=t.child,t.child=null;o!==null;){if(e=o.alternate,e!==null&&Ku(e)===null){t.child=o;break}e=o.sibling,o.sibling=n,n=o,o=e}ro(t,!0,n,null,r,a);break;case"together":ro(t,!1,null,null,void 0,a);break;case"independent":t.memoizedState=null;break;default:n=Om(t.child),n===null?(o=t.child,t.child=null):(o=n.sibling,n.sibling=null),ro(t,!1,o,n,r,a)}return t.child}function zm(e,t,n){var a=t.pendingProps;return vl(t,t.type,a.value),ot(e,t,a.children,n),t.child}function al(e,t,n){if(e!==null&&(t.dependencies=e.dependencies),Tl|=t.lanes,(n&t.childLanes)===0)if(e!==null){if(ma(e,t,n,!1),(n&t.childLanes)===0)return null}else return null;if(e!==null&&t.child!==e.child)throw Error(u(153));if(t.child!==null){for(e=t.child,n=Pn(e,e.pendingProps),t.child=n,n.return=t;e.sibling!==null;)e=e.sibling,n=n.sibling=Pn(e,e.pendingProps),n.return=t;n.sibling=null}return t.child}function Lc(e,t){return(e.lanes&t)!==0?!0:(e=e.dependencies,!!(e!==null&&qu(e)))}function _S(e,t,n){switch(t.tag){case 3:aa(t,t.stateNode.containerInfo),vl(t,nt,e.memoizedState.cache),ha();break;case 27:case 5:Fa(t);break;case 4:aa(t,t.stateNode.containerInfo);break;case 10:vl(t,t.type,t.memoizedProps.value);break;case 31:if(t.memoizedState!==null)return t.flags|=128,oc(t),null;break;case 13:var a=t.memoizedState;if(a!==null){if(a.dehydrated!==null)return El(t),t.flags|=128,null;a=ma(e,t,n,!1);var o=t.child.childLanes;return a||(n&o)!==0?jm(e,t,n):(El(t),e=al(e,t,n),e!==null?e.sibling:null)}El(t);break;case 19:if(t.flags&128)return Hc(e,t,n);if(o=(e.flags&128)!==0,a=(n&t.childLanes)!==0,a||(ma(e,t,n,!1),a=(n&t.childLanes)!==0),o){if(a)return Hc(e,t,n);t.flags|=128}if(o=t.memoizedState,o!==null&&(o.rendering=null,o.tail=null,o.lastEffect=null),Rs(t,xt.current),a)break;return null;case 22:return t.lanes=0,wm(e,t,n,t.pendingProps);case 24:vl(t,nt,e.memoizedState.cache)}return al(e,t,n)}function Dm(e,t,n){if(e!==null)if(e.memoizedProps!==t.pendingProps)at=!0;else{if(!Lc(e,n)&&(t.flags&128)===0)return at=!1,_S(e,t,n);at=(e.flags&131072)!==0}else at=!1,Se&&(t.flags&1048576)!==0&&fg(t,vs,t.index);switch(t.lanes=0,t.tag){case 16:e:{var a=t.pendingProps;if(e=Sa(t.elementType),t.type=e,typeof e=="function")kr(e)?(a=Ea(e,a),t.tag=1,t=Tm(null,t,e,a,n)):(t.tag=0,t=jc(null,t,e,a,n));else{if(e!=null){var o=e.$$typeof;if(o===Y){t.tag=11,t=bm(null,t,e,a,n);break e}else if(o===Ne){t.tag=14,t=Cm(null,t,e,a,n);break e}else if(o===Qe){t.tag=10,t.type=e,t=zm(null,t,n);break e}}throw t=xe(e)||e,Error(u(306,t,""))}}return t;case 0:return jc(e,t,t.type,t.pendingProps,n);case 1:return a=t.type,o=Ea(a,t.pendingProps),Tm(e,t,a,o,n);case 3:e:{if(aa(t,t.stateNode.containerInfo),e===null)throw Error(u(387));a=t.pendingProps;var r=t.memoizedState;o=r.element,lc(e,t),_s(t,a,null,n);var h=t.memoizedState;if(a=h.cache,vl(t,nt,a),a!==r.cache&&Jr(t,[nt],n,!0),ws(),a=h.element,r.isDehydrated)if(r={element:a,isDehydrated:!1,cache:h.cache},t.updateQueue.baseState=r,t.memoizedState=r,t.flags&256){t=Mm(e,t,a,n);break e}else if(a!==o){o=cn(Error(u(424)),t),ys(o),t=Mm(e,t,a,n);break e}else{switch(e=t.stateNode.containerInfo,e.nodeType){case 9:e=e.body;break;default:e=e.nodeName==="HTML"?e.ownerDocument.body:e}for(Ye=mn(e.firstChild),ft=t,Se=!0,ml=null,hn=!0,n=wg(t,null,a,n),t.child=n;n;)n.flags=n.flags&-3|134221824,n=n.sibling}else{if(ha(),a===o){t=al(e,t,n);break e}ot(e,t,a,n)}t=t.child}return t;case 26:return pi(e,t),e===null?(n=iv(t.type,null,t.pendingProps,null))?t.memoizedState=n:Se||(t.stateNode=Vp(t.type,t.pendingProps,yn.current,t)):t.memoizedState=iv(t.type,e.memoizedProps,t.pendingProps,e.memoizedState),null;case 27:return 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ot(e,t,t.pendingProps.children,n),t.child;case 12:return ot(e,t,t.pendingProps.children,n),t.child;case 10:return zm(e,t,n);case 9:return o=t.type._context,a=t.pendingProps.children,pa(t),o=yt(o),a=a(o),t.flags|=1,ot(e,t,a,n),t.child;case 14:return Cm(e,t,t.type,t.pendingProps,n);case 15:return Em(e,t,t.type,t.pendingProps,n);case 19:return Hc(e,t,n);case 31:return ES(e,t,n);case 22:return wm(e,t,n,t.pendingProps);case 24:return pa(t),a=yt(nt),e===null?(o=ec(),o===null&&(o=ke,r=Pr(),o.pooledCache=r,r.refCount++,r!==null&&(o.pooledCacheLanes|=n),o=r),t.memoizedState={parent:a,cache:o},nc(t),vl(t,nt,o)):((e.lanes&n)!==0&&(lc(e,t),_s(t,null,null,n),ws()),o=e.memoizedState,r=t.memoizedState,o.parent!==a?(o={parent:a,cache:a},t.memoizedState=o,t.lanes===0&&(t.memoizedState=t.updateQueue.baseState=o),vl(t,nt,a)):(a=r.cache,vl(t,nt,a),a!==o.cache&&Jr(t,[nt],n,!0))),ot(e,t,t.pendingProps.children,n),t.child;case 30:return t.stateNode===null&&(t.stateNode={autoName:null,paired:null,clones:null,ref:null}),a=t.pendingProps,a.name!=null&&a.name!=="auto"?t.flags|=e===null?18882560:18874368:Se&&Vu(t),e!==null&&e.memoizedProps.name!==a.name?t.flags|=4194816:pi(e,t),ot(e,t,a.children,n),t.child;case 29:throw t.pendingProps}throw Error(u(156,t.tag))}function il(e){e.flags|=4}function Vc(e,t,n,a,o){var r;if((r=(e.mode&32)!==0)&&(r=n===null?rv(t,a):rv(t,a)&&(a.src!==n.src||a.srcSet!==n.srcSet)),r){if(e.flags|=16777216,(o&335544128)===o)if(e.stateNode.complete)e.flags|=8192;else if(mp())e.flags|=8192;else throw xa=Qu,tc}else e.flags&=-16777217}function Um(e,t){if(t.type!=="stylesheet"||(t.state.loading&4)!==0)e.flags&=-16777217;else if(e.flags|=16777216,!cv(t))if(mp())e.flags|=8192;else throw xa=Qu,tc}function co(e,t){t!==null&&(e.flags|=4),e.flags&16384&&(t=e.tag!==22?rh():536870912,e.lanes|=t,bi|=t)}function As(e,t){if(!Se)switch(e.tailMode){case"visible":break;case"collapsed":for(var n=e.tail,a=null;n!==null;)n.alternate!==null&&(a=n),n=n.sibling;a===null?t||e.tail===null?e.tail=null:e.tail.sibling=null:a.sibling=null;break;default:for(t=e.tail,n=null;t!==null;)t.alternate!==null&&(n=t),t=t.sibling;n===null?e.tail=null:n.sibling=null}}function Xe(e){var t=e.alternate!==null&&e.alternate.child===e.child,n=0,a=0;if(t)for(var o=e.child;o!==null;)n|=o.lanes|o.childLanes,a|=o.subtreeFlags&1206910976,a|=o.flags&1206910976,o.return=e,o=o.sibling;else for(o=e.child;o!==null;)n|=o.lanes|o.childLanes,a|=o.subtreeFlags,a|=o.flags,o.return=e,o=o.sibling;return e.subtreeFlags|=a,e.childLanes=n,t}function RS(e,t,n){var a=t.pendingProps;switch(Xr(t),t.tag){case 16:case 15:case 0:case 11:case 7:case 8:case 12:case 9:case 14:return Xe(t),null;case 1:return Xe(t),null;case 3:return n=t.stateNode,a=null,e!==null&&(a=e.memoizedState.cache),t.memoizedState.cache!==a&&(t.flags|=2048),tl(nt),Yn(),n.pendingContext&&(n.context=n.pendingContext,n.pendingContext=null),(e===null||e.child===null)&&(ri(t)?il(t):e===null||e.memoizedState.isDehydrated&&(t.flags&256)===0||(t.flags|=1024,Kr())),Xe(t),null;case 26:var o=t.type,r=t.memoizedState;return e===null?(il(t),r!==null?(Xe(t),Um(t,r)):(Xe(t),Vc(t,o,null,a,n))):r?r!==e.memoizedState?(il(t),Xe(t),Um(t,r)):(Xe(t),t.flags&=-16777217):(e=e.memoizedProps,e!==a&&il(t),Xe(t),Vc(t,o,e,a,n)),null;case 27:if(ia(t),n=yn.current,o=t.type,e!==null&&t.stateNode!=null)e.memoizedProps!==a&&il(t);else{if(!a){if(t.stateNode===null)throw Error(u(166));return Xe(t),t.subtreeFlags&=-33554433,null}e=Vt.current,ri(t)?hg(t):(e=tv(o,a,n),t.stateNode=e,il(t))}return Xe(t),t.subtreeFlags&=-33554433,null;case 5:if(ia(t),o=t.type,e!==null&&t.stateNode!=null)e.memoizedProps!==a&&il(t);else{if(!a){if(t.stateNode===null)throw Error(u(166));return Xe(t),t.subtreeFlags&=-33554433,null}if(r=Vt.current,ri(t))hg(t);else{var h=Fs(yn.current);switch(r){case 1:r=h.createElementNS("http://www.w3.org/2000/svg",o);break;case 2:r=h.createElementNS("http://www.w3.org/1998/Math/MathML",o);break;default:switch(o){case"svg":r=h.createElementNS("http://www.w3.org/2000/svg",o);break;case"math":r=h.createElementNS("http://www.w3.org/1998/Math/MathML",o);break;case"script":r=h.createElement("div"),r.innerHTML="<script><\/script>",r=r.removeChild(r.firstChild);break;case"select":r=typeof a.is=="string"?h.createElement("select",{is:a.is}):h.createElement("select"),a.multiple?r.multiple=!0:a.size&&(r.size=a.size);break;default:r=typeof a.is=="string"?h.createElement(o,{is:a.is}):h.createElement(o)}}r[vt]=t,r[Bt]=a;e:for(h=t.child;h!==null;){if(h.tag===5||h.tag===6)r.appendChild(h.stateNode);else if(h.tag!==4&&h.tag!==27&&h.child!==null){h.child.return=h,h=h.child;continue}if(h===t)break e;for(;h.sibling===null;){if(h.return===null||h.return===t)break e;h=h.return}h.sibling.return=h.return,h=h.sibling}t.stateNode=r;e:switch(Ct(r,o,a),o){case"button":case"input":case"select":case"textarea":a=!!a.autoFocus;break e;case"img":a=!0;break e;default:a=!1}a&&il(t)}}return Xe(t),t.subtreeFlags&=-33554433,Vc(t,t.type,e===null?null:e.memoizedProps,t.pendingProps,n),null;case 6:if(e&&t.stateNode!=null)e.memoizedProps!==a&&il(t);else{if(typeof a!="string"&&t.stateNode===null)throw Error(u(166));if(e=yn.current,ri(t)){if(e=t.stateNode,n=t.memoizedProps,a=null,o=ft,o!==null)switch(o.tag){case 27:case 5:a=o.memoizedProps}e[vt]=t,e=!!(e.nodeValue===n||a!==null&&a.suppressHydrationWarning===!0||Dp(e.nodeValue,n)),e||pl(t,!0)}else e=Fs(e).createTextNode(a),e[vt]=t,t.stateNode=e}return Xe(t),null;case 31:if(n=t.memoizedState,e===null||e.memoizedState!==null){if(a=ri(t),n!==null){if(e===null){if(!a)throw Error(u(318));if(e=t.memoizedState,e=e!==null?e.dehydrated:null,!e)throw Error(u(557));e[vt]=t}else ha(),(t.flags&128)===0&&(t.memoizedState=null),t.flags|=4;Xe(t),e=!1}else n=Kr(),e!==null&&e.memoizedState!==null&&(e.memoizedState.hydrationErrors=n),e=!0;if(!e)return t.flags&256?(Jt(t),t):(Jt(t),null);if((t.flags&128)!==0)throw Error(u(558))}return Xe(t),null;case 13:if(a=t.memoizedState,e===null||e.memoizedState!==null&&e.memoizedState.dehydrated!==null){if(o=ri(t),a!==null&&a.dehydrated!==null){if(e===null){if(!o)throw Error(u(318));if(o=t.memoizedState,o=o!==null?o.dehydrated:null,!o)throw Error(u(317));o[vt]=t}else ha(),(t.flags&128)===0&&(t.memoizedState=null),t.flags|=4;Xe(t),o=!1}else o=Kr(),e!==null&&e.memoizedState!==null&&(e.memoizedState.hydrationErrors=o),o=!0;if(!o)return t.flags&256?(Jt(t),t):(Jt(t),null)}return Jt(t),(t.flags&128)!==0?(t.lanes=n,t):(n=a!==null,e=e!==null&&e.memoizedState!==null,n&&(a=t.child,o=null,a.alternate!==null&&a.alternate.memoizedState!==null&&a.alternate.memoizedState.cachePool!==null&&(o=a.alternate.memoizedState.cachePool.pool),r=null,a.memoizedState!==null&&a.memoizedState.cachePool!==null&&(r=a.memoizedState.cachePool.pool),r!==o&&(a.flags|=2048)),n!==e&&n&&(t.child.flags|=8192),co(t,t.updateQueue),Xe(t),null);case 4:return Yn(),e===null&&xf(t.stateNode.containerInfo),t.flags|=67108864,Xe(t),null;case 10:return tl(t.type),Xe(t),null;case 19:if(rc(t),a=t.memoizedState,a===null)return Xe(t),null;if(o=(t.flags&128)!==0,r=a.rendering,r===null)if(o)As(a,!1);else{if(We!==0||e!==null&&(e.flags&128)!==0)for(e=t.child;e!==null;){if(r=Ku(e),r!==null){for(t.flags|=128,As(a,!1),e=r.updateQueue,t.updateQueue=e,co(t,e),t.subtreeFlags=0,e=n,n=t.child;n!==null;)og(n,e),n=n.sibling;return 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du{constructor(i,s){super();ue(this,ze);ue(this,Ht);ue(this,Te);ue(this,ou);ue(this,Lt);ue(this,Ha);ue(this,$i);ue(this,cl);ue(this,ru);ue(this,ki);ue(this,Qi);ue(this,La);ue(this,Va);ue(this,$l);ue(this,Yi,new Set);this.options=s,K(this,Ht,i),K(this,cl,null),this.bindMethods(),this.setOptions(s)}bindMethods(){this.refetch=this.refetch.bind(this)}onSubscribe(){this.listeners.size===1&&(M(this,Te).addObserver(this),Qv(M(this,Te),this.options)?Re(this,ze,eu).call(this):this.updateResult(),Re(this,ze,Sd).call(this))}onUnsubscribe(){this.hasListeners()||this.destroy()}shouldFetchOnReconnect(){return Ed(M(this,Te),this.options,this.options.refetchOnReconnect)}shouldFetchOnWindowFocus(){return Ed(M(this,Te),this.options,this.options.refetchOnWindowFocus)}destroy(){this.listeners=new Set,Re(this,ze,xd).call(this),Re(this,ze,bd).call(this),M(this,Te).removeObserver(this)}setOptions(i){const 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f=Re(this,ze,vd).call(this);c&&(M(this,Te)!==u||Ke(this.options.enabled,M(this,Te))!==Ke(s.enabled,M(this,Te))||f!==M(this,$l))&&Re(this,ze,yd).call(this,f)}getOptimisticResult(i){const s=M(this,Ht).getQueryCache().build(M(this,Ht),i),u=this.createResult(s,i);return Pf(this.getCurrentResult(),u)||(K(this,Lt,u),K(this,$i,this.options),K(this,Ha,M(this,Te).state)),u}getCurrentResult(){return M(this,Lt)}trackResult(i,s){return new Proxy(i,{get:(u,c)=>(this.trackProp(c),s==null||s(c),Reflect.get(u,c))})}trackProp(i){M(this,Yi).add(i)}getCurrentQuery(){return M(this,Te)}refetch({...i}={}){return this.fetch({...i})}fetchOptimistic(i){const s=M(this,Ht).defaultQueryOptions(i),u=M(this,Ht).getQueryCache().build(M(this,Ht),s);let c=()=>{},f;const g=new Promise(m=>{f=m,c=M(this,Ht).getQueryCache().subscribe(y=>{y.type==="updated"&&y.query.queryHash===u.queryHash&&u.state.data!==void 0&&(c(),m(this.createResult(u,s)))})});return Promise.race([u.fetch(s).then(()=>{const m=this.createResult(u,s);return f==null||f(m),m}).finally(()=>{c()}),g])}fetch(i){return Re(this,ze,eu).call(this,{...i,cancelRefetch:i.cancelRefetch??!0}).then(()=>(this.updateResult(),M(this,Lt)))}createResult(i,s){var P;const u=M(this,Te),c=this.options,f=M(this,Lt),g=M(this,Ha),m=M(this,$i),y=i!==u?i.state:M(this,ou),{state:x}=i;let v={...x},S=!1,b;if(s._optimisticResults){const X=this.hasListeners(),Z=!X&&Qv(i,s),de=X&&Yv(i,u,s,c);(Z||de)&&(v={...v,...$y(x.data,i.options)}),s._optimisticResults==="isRestoring"&&(v.fetchStatus="idle")}let{error:N,errorUpdatedAt:E,status:D}=v;b=v.data;let _=!1;if(s.placeholderData!==void 0&&b===void 0&&D==="pending"){let X;f!=null&&f.isPlaceholderData&&s.placeholderData===(m==null?void 0:m.placeholderData)?(X=f.data,_=!0):X=typeof s.placeholderData=="function"?s.placeholderData((P=M(this,Qi))==null?void 0:P.state.data,M(this,Qi)):s.placeholderData,X!==void 0&&(D="success",b=hd(f==null?void 0:f.data,X,s),S=!0)}if(s.select&&b!==void 0&&!_)if(f&&b===(g==null?void 0:g.data)&&s.select===M(this,ru))b=M(this,ki);else try{K(this,ru,s.select),b=s.select(b),b=hd(f==null?void 0:f.data,b,s),K(this,ki,b),K(this,cl,null)}catch(X){K(this,cl,X)}else b===void 0&&K(this,cl,null);M(this,cl)&&(N=M(this,cl),b=M(this,ki),E=Date.now(),D="error",S=!1);const C=v.fetchStatus==="fetching",U=D==="pending",B=D==="error",$=U&&C,F=b!==void 0;return{status:D,fetchStatus:v.fetchStatus,isPending:U,isSuccess:D==="success",isError:B,isInitialLoading:$,isLoading:$,data:b,dataUpdatedAt:v.dataUpdatedAt,error:N,errorUpdatedAt:E,failureCount:v.fetchFailureCount,failureReason:v.fetchFailureReason,errorUpdateCount:v.errorUpdateCount,isFetched:i.isFetched(),isFetchedAfterMount:v.dataUpdateCount>y.dataUpdateCount||v.errorUpdateCount>y.errorUpdateCount,isFetching:C,isRefetching:C&&!U,isLoadingError:B&&!F,isPaused:v.fetchStatus==="paused",isPlaceholderData:S,isRefetchError:B&&F,isStale:Kd(i,s),refetch:this.refetch,isEnabled:Ke(s.enabled,i)!==!1}}updateResult(){const i=M(this,Lt),s=this.createResult(M(this,Te),this.options);if(K(this,Ha,M(this,Te).state),K(this,$i,this.options),M(this,Ha).data!==void 0&&K(this,Qi,M(this,Te)),Pf(s,i))return;K(this,Lt,s);const c=(()=>{if(!i)return!0;const{notifyOnChangeProps:f}=this.options,g=typeof f=="function"?f():f;if(g==="all"||!g&&!M(this,Yi).size)return!0;const m=new Set(g??M(this,Yi));return this.options.throwOnError&&m.add("error"),Object.keys(M(this,Lt)).some(y=>{const x=y;return M(this,Lt)[x]!==i[x]&&m.has(x)})})();wt.batch(()=>{c&&this.listeners.forEach(f=>{f(M(this,Lt))}),M(this,Ht).getQueryCache().notify({query:M(this,Te),type:"observerResultsUpdated"})})}onQueryUpdate(){this.updateResult(),this.hasListeners()&&Re(this,ze,Sd).call(this)}},Ht=new WeakMap,Te=new WeakMap,ou=new WeakMap,Lt=new WeakMap,Ha=new WeakMap,$i=new WeakMap,cl=new WeakMap,ru=new WeakMap,ki=new WeakMap,Qi=new WeakMap,La=new WeakMap,Va=new WeakMap,$l=new WeakMap,Yi=new WeakMap,ze=new WeakSet,eu=function(i){Re(this,ze,Cd).call(this);let s=M(this,Te).fetch(this.options,i);return i!=null&&i.throwOnError||(s=s.catch(Qt)),s},md=function(i){return!Xd()&&Ke(this.options.enabled,M(this,Te))!==!1&&Dy(i)},pd=function(){Re(this,ze,xd).call(this);const i=Ke(this.options.staleTime,M(this,Te));if(M(this,Lt).isStale||!Re(this,ze,md).call(this,i))return;const s=Uy(M(this,Lt).dataUpdatedAt,i)+1;K(this,La,ja.setTimeout(()=>{M(this,Lt).isStale||this.updateResult()},s))},vd=function(){return Ke(this.options.refetchInterval,M(this,Te))??!1},yd=function(i){Re(this,ze,bd).call(this),K(this,$l,i),!(M(this,$l)===0||!Re(this,ze,md).call(this,M(this,$l)))&&K(this,Va,ja.setInterval(()=>{(this.options.refetchIntervalInBackground||Zd.isFocused())&&Re(this,ze,eu).call(this)},M(this,$l)))},Sd=function(){Re(this,ze,pd).call(this),Re(this,ze,yd).call(this,Re(this,ze,vd).call(this))},xd=function(){M(this,La)!==void 0&&(ja.clearTimeout(M(this,La)),K(this,La,void 0))},bd=function(){M(this,Va)!==void 0&&(ja.clearInterval(M(this,Va)),K(this,Va,void 0))},Cd=function(){const i=M(this,Ht).getQueryCache().build(M(this,Ht),this.options);if(i===M(this,Te))return;const s=M(this,Te);K(this,Te,i),K(this,ou,i.state),this.hasListeners()&&(s==null||s.removeObserver(this),i.addObserver(this))},Ry);function Nb(l,i){return Ke(i.enabled,l)!==!1&&l.state.data===void 0&&!(l.state.status==="error"&&Ke(i.retryOnMount,l)===!1)}function Qv(l,i){return Nb(l,i)||l.state.data!==void 0&&Ed(l,i,i.refetchOnMount)}function Ed(l,i,s){if(Ke(i.enabled,l)!==!1&&Ke(i.staleTime,l)!=="static"){const u=Ke(s,l);return u==="always"||u!==!1&&Kd(l,i)}return!1}function Yv(l,i,s,u){return(l!==i||Ke(u.enabled,l)===!1)&&(!s.suspense||l.state.status!=="error")&&Kd(l,s)}function Kd(l,i){return Ke(i.enabled,l)!==!1&&l.isStaleByTime(Ke(i.staleTime,l))}var cu,qn,Tt,Ba,Fn,Vl,Ny,Tb=(Ny=class extends Fy{constructor(i){super();ue(this,Fn);ue(this,cu);ue(this,qn);ue(this,Tt);ue(this,Ba);K(this,cu,i.client),this.mutationId=i.mutationId,K(this,Tt,i.mutationCache),K(this,qn,[]),this.state=i.state||Mb(),this.setOptions(i.options),this.scheduleGc()}setOptions(i){this.options=i,this.updateGcTime(this.options.gcTime)}get meta(){return this.options.meta}addObserver(i){M(this,qn).includes(i)||(M(this,qn).push(i),this.clearGcTimeout(),M(this,Tt).notify({type:"observerAdded",mutation:this,observer:i}))}removeObserver(i){K(this,qn,M(this,qn).filter(s=>s!==i)),this.scheduleGc(),M(this,Tt).notify({type:"observerRemoved",mutation:this,observer:i})}optionalRemove(){M(this,qn).length||(this.state.status==="pending"?this.scheduleGc():M(this,Tt).remove(this))}continue(){var i;return((i=M(this,Ba))==null?void 0:i.continue())??(this.state.status==="pending"?this.execute(this.state.variables):Promise.resolve())}async execute(i){var m,y,x,v,S,b,N,E,D,_,C,U,B,$,F,P,X,Z;const s=()=>{Re(this,Fn,Vl).call(this,{type:"continue"})},u={client:M(this,cu),meta:this.options.meta,mutationKey:this.options.mutationKey},c=K(this,Ba,qy({fn:()=>this.options.mutationFn?this.options.mutationFn(i,u):Promise.reject(new Error("No mutationFn found")),onFail:(de,ve)=>{Re(this,Fn,Vl).call(this,{type:"failed",failureCount:de,error:ve})},onPause:()=>{Re(this,Fn,Vl).call(this,{type:"pause"})},onContinue:s,retry:this.options.retry??0,retryDelay:this.options.retryDelay,networkMode:this.options.networkMode,canRun:()=>M(this,Tt).canRun(this)})),f=this.state.status==="pending",g=!c.canStart();try{if(f)s();else{Re(this,Fn,Vl).call(this,{type:"pending",variables:i,isPaused:g}),M(this,Tt).config.onMutate&&await M(this,Tt).config.onMutate(i,this,u);const ve=await((y=(m=this.options).onMutate)==null?void 0:y.call(m,i,u));ve!==this.state.context&&Re(this,Fn,Vl).call(this,{type:"pending",context:ve,variables:i,isPaused:g})}const de=await c.start();return await((v=(x=M(this,Tt).config).onSuccess)==null?void 0:v.call(x,de,i,this.state.context,this,u)),await((b=(S=this.options).onSuccess)==null?void 0:b.call(S,de,i,this.state.context,u)),await((E=(N=M(this,Tt).config).onSettled)==null?void 0:E.call(N,de,null,this.state.variables,this.state.context,this,u)),await((_=(D=this.options).onSettled)==null?void 0:_.call(D,de,null,i,this.state.context,u)),Re(this,Fn,Vl).call(this,{type:"success",data:de}),de}catch(de){try{await((U=(C=M(this,Tt).config).onError)==null?void 0:U.call(C,de,i,this.state.context,this,u))}catch(ve){Promise.reject(ve)}try{await(($=(B=this.options).onError)==null?void 0:$.call(B,de,i,this.state.context,u))}catch(ve){Promise.reject(ve)}try{await((P=(F=M(this,Tt).config).onSettled)==null?void 0:P.call(F,void 0,de,this.state.variables,this.state.context,this,u))}catch(ve){Promise.reject(ve)}try{await((Z=(X=this.options).onSettled)==null?void 0:Z.call(X,void 0,de,i,this.state.context,u))}catch(ve){Promise.reject(ve)}throw Re(this,Fn,Vl).call(this,{type:"error",error:de}),de}finally{M(this,Ba)===c&&K(this,Ba,void 0),M(this,Tt).runNext(this)}}},cu=new WeakMap,qn=new WeakMap,Tt=new WeakMap,Ba=new WeakMap,Fn=new WeakSet,Vl=function(i){const s=u=>{switch(i.type){case"failed":return{...u,failureCount:i.failureCount,failureReason:i.error};case"pause":return{...u,isPaused:!0};case"continue":return{...u,isPaused:!1};case"pending":return{...u,context:i.context,data:void 0,failureCount:0,failureReason:null,error:null,isPaused:i.isPaused,status:"pending",variables:i.variables,submittedAt:Date.now()};case"success":return{...u,data:i.data,failureCount:0,failureReason:null,error:null,status:"success",isPaused:!1};case"error":return{...u,data:void 0,error:i.error,failureCount:u.failureCount+1,failureReason:i.error,isPaused:!1,status:"error"}}};this.state=s(this.state),wt.batch(()=>{M(this,qn).forEach(u=>{u.onMutationUpdate(i)}),M(this,Tt).notify({mutation:this,type:"updated",action:i})})},Ny);function Mb(){return{context:void 0,data:void 0,error:null,failureCount:0,failureReason:null,isPaused:!1,status:"idle",variables:void 0,submittedAt:0}}var kl,Nn,fu,Ty,jb=(Ty=class extends du{constructor(i={}){super();ue(this,kl);ue(this,Nn);ue(this,fu);this.config=i,K(this,kl,new Set),K(this,Nn,new Map),K(this,fu,0)}build(i,s,u){const c=new Tb({client:i,mutationCache:this,mutationId:++ko(this,fu)._,options:i.defaultMutationOptions(s),state:u});return this.add(c),c}add(i){M(this,kl).add(i);const s=Qo(i);if(typeof s=="string"){const u=M(this,Nn).get(s);u?u.push(i):M(this,Nn).set(s,[i])}this.notify({type:"added",mutation:i})}remove(i){if(M(this,kl).delete(i)){const s=Qo(i);if(typeof s=="string"){const u=M(this,Nn).get(s);if(u)if(u.length>1){const c=u.indexOf(i);c!==-1&&u.splice(c,1)}else u[0]===i&&M(this,Nn).delete(s)}}this.notify({type:"removed",mutation:i})}canRun(i){var u;const s=Qo(i);if(typeof s=="string"){const c=(u=M(this,Nn).get(s))==null?void 0:u.find(f=>f.state.status==="pending");return!c||c===i}else return!0}runNext(i){var u,c;const s=Qo(i);return typeof s=="string"?((c=(u=M(this,Nn).get(s))==null?void 0:u.find(f=>f!==i&&f.state.isPaused))==null?void 0:c.continue())??Promise.resolve():Promise.resolve()}clear(){wt.batch(()=>{const i=this.getAll();M(this,kl).clear(),M(this,Nn).clear(),i.forEach(s=>{this.notify({type:"removed",mutation:s})})})}getAll(){return Array.from(M(this,kl))}find(i){const s={exact:!0,...i};return this.getAll().find(u=>Bv(s,u))}findAll(i={}){return this.getAll().filter(s=>Bv(i,s))}notify(i){wt.batch(()=>{this.listeners.forEach(s=>{s(i)})})}resumePausedMutations(){const i=this.getAll().filter(s=>s.state.isPaused);return wt.batch(()=>Promise.all(i.map(s=>s.continue().catch(Qt))))}},kl=new WeakMap,Nn=new WeakMap,fu=new WeakMap,Ty);function Qo(l){var i;return(i=l.options.scope)==null?void 0:i.id}var $n,My,Ab=(My=class extends du{constructor(i={}){super();ue(this,$n);this.config=i,K(this,$n,new Map)}build(i,s,u){const c=s.queryKey,f=s.queryHash??Qd(c,s);let g=this.get(f);return g||(g=new _b({client:i,queryKey:c,queryHash:f,options:i.defaultQueryOptions(s),state:u,defaultOptions:i.getQueryDefaults(c)}),this.add(g)),g}add(i){M(this,$n).has(i.queryHash)||(M(this,$n).set(i.queryHash,i),this.notify({type:"added",query:i}))}remove(i){M(this,$n).get(i.queryHash)===i&&(i.destroy(),M(this,$n).delete(i.queryHash),this.notify({type:"removed",query:i}))}clear(){wt.batch(()=>{this.getAll().forEach(i=>{this.remove(i)})})}get(i){return M(this,$n).get(i)}getAll(){return[...M(this,$n).values()]}find(i){const s={exact:!0,...i};return this.getAll().find(u=>Vv(s,u))}findAll(i={}){const s=this.getAll();return Object.keys(i).length>0?s.filter(u=>Vv(i,u)):s}notify(i){wt.batch(()=>{this.listeners.forEach(s=>{s(i)})})}onFocus(){wt.batch(()=>{this.getAll().forEach(i=>{i.onFocus()})})}onOnline(){wt.batch(()=>{this.getAll().forEach(i=>{i.onOnline()})})}},$n=new WeakMap,My),Je,Ql,Yl,Xi,Zi,Xl,Ki,Ii,jy,Ob=(jy=class{constructor(l={}){ue(this,Je);ue(this,Ql);ue(this,Yl);ue(this,Xi);ue(this,Zi);ue(this,Xl);ue(this,Ki);ue(this,Ii);K(this,Je,l.queryCache||new Ab),K(this,Ql,l.mutationCache||new jb),K(this,Yl,l.defaultOptions||{}),K(this,Xi,new Map),K(this,Zi,new Map),K(this,Xl,0)}mount(){ko(this,Xl)._++,M(this,Xl)===1&&(K(this,Ki,Zd.subscribe(async l=>{l&&(await this.resumePausedMutations(),M(this,Je).onFocus())})),K(this,Ii,Io.subscribe(async l=>{l&&(await this.resumePausedMutations(),M(this,Je).onOnline())})))}unmount(){var l,i;ko(this,Xl)._--,M(this,Xl)===0&&((l=M(this,Ki))==null||l.call(this),K(this,Ki,void 0),(i=M(this,Ii))==null||i.call(this),K(this,Ii,void 0))}isFetching(l){return M(this,Je).findAll({...l,fetchStatus:"fetching"}).length}isMutating(l){return M(this,Ql).findAll({...l,status:"pending"}).length}getQueryData(l){var s;const i=this.defaultQueryOptions({queryKey:l});return(s=M(this,Je).get(i.queryHash))==null?void 0:s.state.data}ensureQueryData(l){const i=this.defaultQueryOptions(l),s=M(this,Je).build(this,i),u=s.state.data;return u===void 0?this.fetchQuery(l):(l.revalidateIfStale&&s.isStaleByTime(Ke(i.staleTime,s))&&this.prefetchQuery(i),Promise.resolve(u))}getQueriesData(l){return M(this,Je).findAll(l).map(({queryKey:i,state:s})=>[i,s.data])}setQueryData(l,i,s){var g;const u=this.defaultQueryOptions({queryKey:l}),c=(g=M(this,Je).get(u.queryHash))==null?void 0:g.state.data,f=fb(i,c);if(f!==void 0)return M(this,Je).build(this,u).setData(f,{...s,manual:!0})}setQueriesData(l,i,s){return wt.batch(()=>M(this,Je).findAll(l).map(({queryKey:u})=>[u,this.setQueryData(u,i,s)]))}getQueryState(l){var s;const i=this.defaultQueryOptions({queryKey:l});return(s=M(this,Je).get(i.queryHash))==null?void 0:s.state}removeQueries(l){const i=M(this,Je);wt.batch(()=>{i.findAll(l).forEach(s=>{i.remove(s)})})}resetQueries(l,i){const s=M(this,Je);return wt.batch(()=>{const u=s.findAll(l),c=new Set(u);return u.forEach(f=>{f.reset()}),this.refetchQueries({type:"active",predicate:f=>c.has(f)},i)})}cancelQueries(l,i={}){const s={revert:!0,...i},u=wt.batch(()=>M(this,Je).findAll(l).map(c=>c.cancel(s)));return Promise.all(u).then(Qt).catch(Qt)}invalidateQueries(l,i={}){return wt.batch(()=>(M(this,Je).findAll(l).forEach(s=>{s.invalidate()}),(l==null?void 0:l.refetchType)==="none"?Promise.resolve():this.refetchQueries({...l,type:(l==null?void 0:l.refetchType)??(l==null?void 0:l.type)??"active"},i)))}refetchQueries(l,i={}){const s={...i,cancelRefetch:i.cancelRefetch??!0},u=wt.batch(()=>M(this,Je).findAll(l).filter(c=>!c.isDisabled()&&!c.isStatic()).map(c=>{let f=c.fetch(void 0,s);return s.throwOnError||(f=f.catch(Qt)),c.state.fetchStatus==="paused"?Promise.resolve():f}));return Promise.all(u).then(Qt)}async query(l){const i=this.defaultQueryOptions(l);i.retry===void 0&&(i.retry=!1);const s=M(this,Je).build(this,i),u=s.isStaleByTime(Ke(i.staleTime,s))?await s.fetch(i):s.state.data,c=i.select;return 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Oa,Ry,$y=(Ry=class{constructor(){ue(this,Oa)}destroy(){this.clearGcTimeout()}scheduleGc(){this.clearGcTimeout(),Uy(this.gcTime)&&K(this,Oa,ja.setTimeout(()=>{this.optionalRemove()},this.gcTime))}updateGcTime(l){this.gcTime=Math.max(this.gcTime||0,l??(Xd()?1/0:3e5))}clearGcTimeout(){M(this,Oa)!==void 0&&(ja.clearTimeout(M(this,Oa)),K(this,Oa,void 0))}},Oa=new WeakMap,Ry);function _b(l){return{onFetch:(i,s)=>{var y,x,C,R,_;const u=i.options,c=(C=(x=(y=i.fetchOptions)==null?void 0:y.meta)==null?void 0:x.fetchMore)==null?void 0:C.direction,f=((R=i.state.data)==null?void 0:R.pages)||[],g=((_=i.state.data)==null?void 0:_.pageParams)||[];let m={pages:[],pageParams:[]},v=0;const S=async()=>{let O=!1;const b=B=>{Sb(B,()=>i.signal,()=>O=!0)},E=By(i.options,i.fetchOptions),U=async(B,$,F)=>{if(O)return Promise.reject(i.signal.reason);if($==null&&B.pages.length)return Promise.resolve(B);const X=(()=>{const 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$y{constructor(i){super();ue(this,_n);ue(this,qi);ue(this,za);ue(this,Fi);ue(this,vn);ue(this,Da);ue(this,rt);ue(this,uu);ue(this,Ua);K(this,Ua,!1),K(this,uu,i.defaultOptions),this.setOptions(i.options),this.observers=[],K(this,Da,i.client),K(this,vn,M(this,Da).getQueryCache()),this.queryKey=i.queryKey,this.queryHash=i.queryHash,K(this,za,Qv(this.options)),this.state=i.state??M(this,za),this.scheduleGc()}get meta(){return this.options.meta}get queryType(){return M(this,qi)}get promise(){var i;return(i=M(this,rt))==null?void 0:i.promise}setOptions(i){if(this.options={...M(this,uu),...i},i!=null&&i._type&&K(this,qi,i._type),this.updateGcTime(this.options.gcTime),this.state&&this.state.data===void 0){const s=Qv(this.options);s.data!==void 0&&(this.setState(kv(s.data,s.dataUpdatedAt)),K(this,za,s))}}optionalRemove(){!this.observers.length&&this.state.fetchStatus==="idle"&&M(this,vn).remove(this)}setData(i,s){const u=hd(this.state.data,i,this.options);return 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du{constructor(i,s){super();ue(this,ze);ue(this,Ht);ue(this,Te);ue(this,ou);ue(this,Lt);ue(this,Ha);ue(this,$i);ue(this,cl);ue(this,ru);ue(this,ki);ue(this,Qi);ue(this,La);ue(this,Va);ue(this,$l);ue(this,Yi,new Set);this.options=s,K(this,Ht,i),K(this,cl,null),this.bindMethods(),this.setOptions(s)}bindMethods(){this.refetch=this.refetch.bind(this)}onSubscribe(){this.listeners.size===1&&(M(this,Te).addObserver(this),Yv(M(this,Te),this.options)?_e(this,ze,eu).call(this):this.updateResult(),_e(this,ze,Sd).call(this))}onUnsubscribe(){this.hasListeners()||this.destroy()}shouldFetchOnReconnect(){return Ed(M(this,Te),this.options,this.options.refetchOnReconnect)}shouldFetchOnWindowFocus(){return Ed(M(this,Te),this.options,this.options.refetchOnWindowFocus)}destroy(){this.listeners=new Set,_e(this,ze,xd).call(this),_e(this,ze,bd).call(this),M(this,Te).removeObserver(this)}setOptions(i){const 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f=_e(this,ze,vd).call(this);c&&(M(this,Te)!==u||Ke(this.options.enabled,M(this,Te))!==Ke(s.enabled,M(this,Te))||f!==M(this,$l))&&_e(this,ze,yd).call(this,f)}getOptimisticResult(i){const s=M(this,Ht).getQueryCache().build(M(this,Ht),i),u=this.createResult(s,i);return Pf(this.getCurrentResult(),u)||(K(this,Lt,u),K(this,$i,this.options),K(this,Ha,M(this,Te).state)),u}getCurrentResult(){return M(this,Lt)}trackResult(i,s){return new Proxy(i,{get:(u,c)=>(this.trackProp(c),s==null||s(c),Reflect.get(u,c))})}trackProp(i){M(this,Yi).add(i)}getCurrentQuery(){return M(this,Te)}refetch({...i}={}){return this.fetch({...i})}fetchOptimistic(i){const s=M(this,Ht).defaultQueryOptions(i),u=M(this,Ht).getQueryCache().build(M(this,Ht),s);let c=()=>{},f;const g=new Promise(m=>{f=m,c=M(this,Ht).getQueryCache().subscribe(v=>{v.type==="updated"&&v.query.queryHash===u.queryHash&&u.state.data!==void 0&&(c(),m(this.createResult(u,s)))})});return Promise.race([u.fetch(s).then(()=>{const m=this.createResult(u,s);return f==null||f(m),m}).finally(()=>{c()}),g])}fetch(i){return _e(this,ze,eu).call(this,{...i,cancelRefetch:i.cancelRefetch??!0}).then(()=>(this.updateResult(),M(this,Lt)))}createResult(i,s){var P;const u=M(this,Te),c=this.options,f=M(this,Lt),g=M(this,Ha),m=M(this,$i),v=i!==u?i.state:M(this,ou),{state:S}=i;let y={...S},x=!1,C;if(s._optimisticResults){const X=this.hasListeners(),Z=!X&&Yv(i,s),de=X&&Xv(i,u,s,c);(Z||de)&&(y={...y,...ky(S.data,i.options)}),s._optimisticResults==="isRestoring"&&(y.fetchStatus="idle")}let{error:R,errorUpdatedAt:_,status:O}=y;C=y.data;let b=!1;if(s.placeholderData!==void 0&&C===void 0&&O==="pending"){let X;f!=null&&f.isPlaceholderData&&s.placeholderData===(m==null?void 0:m.placeholderData)?(X=f.data,b=!0):X=typeof s.placeholderData=="function"?s.placeholderData((P=M(this,Qi))==null?void 0:P.state.data,M(this,Qi)):s.placeholderData,X!==void 0&&(O="success",C=hd(f==null?void 0:f.data,X,s),x=!0)}if(s.select&&C!==void 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this.options.throwOnError&&m.add("error"),Object.keys(M(this,Lt)).some(v=>{const S=v;return M(this,Lt)[S]!==i[S]&&m.has(S)})})();wt.batch(()=>{c&&this.listeners.forEach(f=>{f(M(this,Lt))}),M(this,Ht).getQueryCache().notify({query:M(this,Te),type:"observerResultsUpdated"})})}onQueryUpdate(){this.updateResult(),this.hasListeners()&&_e(this,ze,Sd).call(this)}},Ht=new WeakMap,Te=new WeakMap,ou=new WeakMap,Lt=new WeakMap,Ha=new WeakMap,$i=new WeakMap,cl=new WeakMap,ru=new WeakMap,ki=new WeakMap,Qi=new WeakMap,La=new WeakMap,Va=new WeakMap,$l=new WeakMap,Yi=new WeakMap,ze=new WeakSet,eu=function(i){_e(this,ze,Cd).call(this);let s=M(this,Te).fetch(this.options,i);return i!=null&&i.throwOnError||(s=s.catch(Qt)),s},md=function(i){return!Xd()&&Ke(this.options.enabled,M(this,Te))!==!1&&Uy(i)},pd=function(){_e(this,ze,xd).call(this);const i=Ke(this.options.staleTime,M(this,Te));if(M(this,Lt).isStale||!_e(this,ze,md).call(this,i))return;const s=Hy(M(this,Lt).dataUpdatedAt,i)+1;K(this,La,ja.setTimeout(()=>{M(this,Lt).isStale||this.updateResult()},s))},vd=function(){return Ke(this.options.refetchInterval,M(this,Te))??!1},yd=function(i){_e(this,ze,bd).call(this),K(this,$l,i),!(M(this,$l)===0||!_e(this,ze,md).call(this,M(this,$l)))&&K(this,Va,ja.setInterval(()=>{(this.options.refetchIntervalInBackground||Zd.isFocused())&&_e(this,ze,eu).call(this)},M(this,$l)))},Sd=function(){_e(this,ze,pd).call(this),_e(this,ze,yd).call(this,_e(this,ze,vd).call(this))},xd=function(){M(this,La)!==void 0&&(ja.clearTimeout(M(this,La)),K(this,La,void 0))},bd=function(){M(this,Va)!==void 0&&(ja.clearInterval(M(this,Va)),K(this,Va,void 0))},Cd=function(){const i=M(this,Ht).getQueryCache().build(M(this,Ht),this.options);if(i===M(this,Te))return;const s=M(this,Te);K(this,Te,i),K(this,ou,i.state),this.hasListeners()&&(s==null||s.removeObserver(this),i.addObserver(this))},Ny);function jb(l,i){return Ke(i.enabled,l)!==!1&&l.state.data===void 0&&!(l.state.status==="error"&&Ke(i.retryOnMount,l)===!1)}function Yv(l,i){return jb(l,i)||l.state.data!==void 0&&Ed(l,i,i.refetchOnMount)}function Ed(l,i,s){if(Ke(i.enabled,l)!==!1&&Ke(i.staleTime,l)!=="static"){const u=Ke(s,l);return u==="always"||u!==!1&&Kd(l,i)}return!1}function Xv(l,i,s,u){return(l!==i||Ke(u.enabled,l)===!1)&&(!s.suspense||l.state.status!=="error")&&Kd(l,s)}function Kd(l,i){return Ke(i.enabled,l)!==!1&&l.isStaleByTime(Ke(i.staleTime,l))}var cu,qn,Tt,Ba,Fn,Vl,Ty,Ab=(Ty=class extends $y{constructor(i){super();ue(this,Fn);ue(this,cu);ue(this,qn);ue(this,Tt);ue(this,Ba);K(this,cu,i.client),this.mutationId=i.mutationId,K(this,Tt,i.mutationCache),K(this,qn,[]),this.state=i.state||Ob(),this.setOptions(i.options),this.scheduleGc()}setOptions(i){this.options=i,this.updateGcTime(this.options.gcTime)}get meta(){return this.options.meta}addObserver(i){M(this,qn).includes(i)||(M(this,qn).push(i),this.clearGcTimeout(),M(this,Tt).notify({type:"observerAdded",mutation:this,observer:i}))}removeObserver(i){K(this,qn,M(this,qn).filter(s=>s!==i)),this.scheduleGc(),M(this,Tt).notify({type:"observerRemoved",mutation:this,observer:i})}optionalRemove(){M(this,qn).length||(this.state.status==="pending"?this.scheduleGc():M(this,Tt).remove(this))}continue(){var i;return((i=M(this,Ba))==null?void 0:i.continue())??(this.state.status==="pending"?this.execute(this.state.variables):Promise.resolve())}async execute(i){var m,v,S,y,x,C,R,_,O,b,E,U,B,$,F,P,X,Z;const s=()=>{_e(this,Fn,Vl).call(this,{type:"continue"})},u={client:M(this,cu),meta:this.options.meta,mutationKey:this.options.mutationKey},c=K(this,Ba,Fy({fn:()=>this.options.mutationFn?this.options.mutationFn(i,u):Promise.reject(new Error("No mutationFn found")),onFail:(de,ve)=>{_e(this,Fn,Vl).call(this,{type:"failed",failureCount:de,error:ve})},onPause:()=>{_e(this,Fn,Vl).call(this,{type:"pause"})},onContinue:s,retry:this.options.retry??0,retryDelay:this.options.retryDelay,networkMode:this.options.networkMode,canRun:()=>M(this,Tt).canRun(this)})),f=this.state.status==="pending",g=!c.canStart();try{if(f)s();else{_e(this,Fn,Vl).call(this,{type:"pending",variables:i,isPaused:g}),M(this,Tt).config.onMutate&&await M(this,Tt).config.onMutate(i,this,u);const ve=await((v=(m=this.options).onMutate)==null?void 0:v.call(m,i,u));ve!==this.state.context&&_e(this,Fn,Vl).call(this,{type:"pending",context:ve,variables:i,isPaused:g})}const de=await c.start();return await((y=(S=M(this,Tt).config).onSuccess)==null?void 0:y.call(S,de,i,this.state.context,this,u)),await((C=(x=this.options).onSuccess)==null?void 0:C.call(x,de,i,this.state.context,u)),await((_=(R=M(this,Tt).config).onSettled)==null?void 0:_.call(R,de,null,this.state.variables,this.state.context,this,u)),await((b=(O=this.options).onSettled)==null?void 0:b.call(O,de,null,i,this.state.context,u)),_e(this,Fn,Vl).call(this,{type:"success",data:de}),de}catch(de){try{await((U=(E=M(this,Tt).config).onError)==null?void 0:U.call(E,de,i,this.state.context,this,u))}catch(ve){Promise.reject(ve)}try{await(($=(B=this.options).onError)==null?void 0:$.call(B,de,i,this.state.context,u))}catch(ve){Promise.reject(ve)}try{await((P=(F=M(this,Tt).config).onSettled)==null?void 0:P.call(F,void 0,de,this.state.variables,this.state.context,this,u))}catch(ve){Promise.reject(ve)}try{await((Z=(X=this.options).onSettled)==null?void 0:Z.call(X,void 0,de,i,this.state.context,u))}catch(ve){Promise.reject(ve)}throw _e(this,Fn,Vl).call(this,{type:"error",error:de}),de}finally{M(this,Ba)===c&&K(this,Ba,void 0),M(this,Tt).runNext(this)}}},cu=new WeakMap,qn=new WeakMap,Tt=new WeakMap,Ba=new WeakMap,Fn=new WeakSet,Vl=function(i){const s=u=>{switch(i.type){case"failed":return{...u,failureCount:i.failureCount,failureReason:i.error};case"pause":return{...u,isPaused:!0};case"continue":return{...u,isPaused:!1};case"pending":return{...u,context:i.context,data:void 0,failureCount:0,failureReason:null,error:null,isPaused:i.isPaused,status:"pending",variables:i.variables,submittedAt:Date.now()};case"success":return{...u,data:i.data,failureCount:0,failureReason:null,error:null,status:"success",isPaused:!1};case"error":return{...u,data:void 0,error:i.error,failureCount:u.failureCount+1,failureReason:i.error,isPaused:!1,status:"error"}}};this.state=s(this.state),wt.batch(()=>{M(this,qn).forEach(u=>{u.onMutationUpdate(i)}),M(this,Tt).notify({mutation:this,type:"updated",action:i})})},Ty);function Ob(){return{context:void 0,data:void 0,error:null,failureCount:0,failureReason:null,isPaused:!1,status:"idle",variables:void 0,submittedAt:0}}var kl,Nn,fu,My,zb=(My=class extends du{constructor(i={}){super();ue(this,kl);ue(this,Nn);ue(this,fu);this.config=i,K(this,kl,new Set),K(this,Nn,new Map),K(this,fu,0)}build(i,s,u){const c=new Ab({client:i,mutationCache:this,mutationId:++Qo(this,fu)._,options:i.defaultMutationOptions(s),state:u});return this.add(c),c}add(i){M(this,kl).add(i);const s=Yo(i);if(typeof s=="string"){const u=M(this,Nn).get(s);u?u.push(i):M(this,Nn).set(s,[i])}this.notify({type:"added",mutation:i})}remove(i){if(M(this,kl).delete(i)){const s=Yo(i);if(typeof s=="string"){const u=M(this,Nn).get(s);if(u)if(u.length>1){const c=u.indexOf(i);c!==-1&&u.splice(c,1)}else u[0]===i&&M(this,Nn).delete(s)}}this.notify({type:"removed",mutation:i})}canRun(i){var u;const s=Yo(i);if(typeof s=="string"){const c=(u=M(this,Nn).get(s))==null?void 0:u.find(f=>f.state.status==="pending");return!c||c===i}else return!0}runNext(i){var u,c;const s=Yo(i);return typeof s=="string"?((c=(u=M(this,Nn).get(s))==null?void 0:u.find(f=>f!==i&&f.state.isPaused))==null?void 0:c.continue())??Promise.resolve():Promise.resolve()}clear(){wt.batch(()=>{const i=this.getAll();M(this,kl).clear(),M(this,Nn).clear(),i.forEach(s=>{this.notify({type:"removed",mutation:s})})})}getAll(){return Array.from(M(this,kl))}find(i){const s={exact:!0,...i};return this.getAll().find(u=>Gv(s,u))}findAll(i={}){return this.getAll().filter(s=>Gv(i,s))}notify(i){wt.batch(()=>{this.listeners.forEach(s=>{s(i)})})}resumePausedMutations(){const i=this.getAll().filter(s=>s.state.isPaused);return wt.batch(()=>Promise.all(i.map(s=>s.continue().catch(Qt))))}},kl=new WeakMap,Nn=new WeakMap,fu=new WeakMap,My);function Yo(l){var i;return(i=l.options.scope)==null?void 0:i.id}var $n,jy,Db=(jy=class extends du{constructor(i={}){super();ue(this,$n);this.config=i,K(this,$n,new Map)}build(i,s,u){const c=s.queryKey,f=s.queryHash??Qd(c,s);let g=this.get(f);return g||(g=new Tb({client:i,queryKey:c,queryHash:f,options:i.defaultQueryOptions(s),state:u,defaultOptions:i.getQueryDefaults(c)}),this.add(g)),g}add(i){M(this,$n).has(i.queryHash)||(M(this,$n).set(i.queryHash,i),this.notify({type:"added",query:i}))}remove(i){M(this,$n).get(i.queryHash)===i&&(i.destroy(),M(this,$n).delete(i.queryHash),this.notify({type:"removed",query:i}))}clear(){wt.batch(()=>{this.getAll().forEach(i=>{this.remove(i)})})}get(i){return M(this,$n).get(i)}getAll(){return[...M(this,$n).values()]}find(i){const s={exact:!0,...i};return this.getAll().find(u=>Bv(s,u))}findAll(i={}){const s=this.getAll();return Object.keys(i).length>0?s.filter(u=>Bv(i,u)):s}notify(i){wt.batch(()=>{this.listeners.forEach(s=>{s(i)})})}onFocus(){wt.batch(()=>{this.getAll().forEach(i=>{i.onFocus()})})}onOnline(){wt.batch(()=>{this.getAll().forEach(i=>{i.onOnline()})})}},$n=new WeakMap,jy),Je,Ql,Yl,Xi,Zi,Xl,Ki,Ii,Ay,Ub=(Ay=class{constructor(l={}){ue(this,Je);ue(this,Ql);ue(this,Yl);ue(this,Xi);ue(this,Zi);ue(this,Xl);ue(this,Ki);ue(this,Ii);K(this,Je,l.queryCache||new Db),K(this,Ql,l.mutationCache||new zb),K(this,Yl,l.defaultOptions||{}),K(this,Xi,new Map),K(this,Zi,new Map),K(this,Xl,0)}mount(){Qo(this,Xl)._++,M(this,Xl)===1&&(K(this,Ki,Zd.subscribe(async l=>{l&&(await this.resumePausedMutations(),M(this,Je).onFocus())})),K(this,Ii,Jo.subscribe(async l=>{l&&(await this.resumePausedMutations(),M(this,Je).onOnline())})))}unmount(){var l,i;Qo(this,Xl)._--,M(this,Xl)===0&&((l=M(this,Ki))==null||l.call(this),K(this,Ki,void 0),(i=M(this,Ii))==null||i.call(this),K(this,Ii,void 0))}isFetching(l){return M(this,Je).findAll({...l,fetchStatus:"fetching"}).length}isMutating(l){return M(this,Ql).findAll({...l,status:"pending"}).length}getQueryData(l){var s;const i=this.defaultQueryOptions({queryKey:l});return(s=M(this,Je).get(i.queryHash))==null?void 0:s.state.data}ensureQueryData(l){const i=this.defaultQueryOptions(l),s=M(this,Je).build(this,i),u=s.state.data;return u===void 0?this.fetchQuery(l):(l.revalidateIfStale&&s.isStaleByTime(Ke(i.staleTime,s))&&this.prefetchQuery(i),Promise.resolve(u))}getQueriesData(l){return M(this,Je).findAll(l).map(({queryKey:i,state:s})=>[i,s.data])}setQueryData(l,i,s){var g;const u=this.defaultQueryOptions({queryKey:l}),c=(g=M(this,Je).get(u.queryHash))==null?void 0:g.state.data,f=gb(i,c);if(f!==void 0)return M(this,Je).build(this,u).setData(f,{...s,manual:!0})}setQueriesData(l,i,s){return wt.batch(()=>M(this,Je).findAll(l).map(({queryKey:u})=>[u,this.setQueryData(u,i,s)]))}getQueryState(l){var s;const i=this.defaultQueryOptions({queryKey:l});return(s=M(this,Je).get(i.queryHash))==null?void 0:s.state}removeQueries(l){const i=M(this,Je);wt.batch(()=>{i.findAll(l).forEach(s=>{i.remove(s)})})}resetQueries(l,i){const s=M(this,Je);return wt.batch(()=>{const u=s.findAll(l),c=new Set(u);return u.forEach(f=>{f.reset()}),this.refetchQueries({type:"active",predicate:f=>c.has(f)},i)})}cancelQueries(l,i={}){const s={revert:!0,...i},u=wt.batch(()=>M(this,Je).findAll(l).map(c=>c.cancel(s)));return Promise.all(u).then(Qt).catch(Qt)}invalidateQueries(l,i={}){return wt.batch(()=>(M(this,Je).findAll(l).forEach(s=>{s.invalidate()}),(l==null?void 0:l.refetchType)==="none"?Promise.resolve():this.refetchQueries({...l,type:(l==null?void 0:l.refetchType)??(l==null?void 0:l.type)??"active"},i)))}refetchQueries(l,i={}){const s={...i,cancelRefetch:i.cancelRefetch??!0},u=wt.batch(()=>M(this,Je).findAll(l).filter(c=>!c.isDisabled()&&!c.isStatic()).map(c=>{let f=c.fetch(void 0,s);return s.throwOnError||(f=f.catch(Qt)),c.state.fetchStatus==="paused"?Promise.resolve():f}));return Promise.all(u).then(Qt)}async query(l){const i=this.defaultQueryOptions(l);i.retry===void 0&&(i.retry=!1);const s=M(this,Je).build(this,i),u=s.isStaleByTime(Ke(i.staleTime,s))?await s.fetch(i):s.state.data,c=i.select;return c?c(u):u}fetchQuery(l){const i=this.defaultQueryOptions(l);i.retry===void 0&&(i.retry=!1);const s=M(this,Je).build(this,i);return s.isStaleByTime(Ke(i.staleTime,s))?s.fetch(i):Promise.resolve(s.state.data)}prefetchQuery(l){return this.fetchQuery(l).then(Qt).catch(Qt)}infiniteQuery(l){return l._type="infinite",this.query(l)}fetchInfiniteQuery(l){return l._type="infinite",this.fetchQuery(l)}prefetchInfiniteQuery(l){return this.fetchInfiniteQuery(l).then(Qt).catch(Qt)}ensureInfiniteQueryData(l){return l._type="infinite",this.ensureQueryData(l)}resumePausedMutations(){return Jo.isOnline()?M(this,Ql).resumePausedMutations():Promise.resolve()}getQueryCache(){return M(this,Je)}getMutationCache(){return M(this,Ql)}getDefaultOptions(){return M(this,Yl)}setDefaultOptions(l){K(this,Yl,l)}setQueryDefaults(l,i){M(this,Xi).set(lu(l),{queryKey:l,defaultOptions:i})}getQueryDefaults(l){const i=[...M(this,Xi).values()],s={};return i.forEach(u=>{Ji(l,u.queryKey)&&Object.assign(s,u.defaultOptions)}),s}setMutationDefaults(l,i){M(this,Zi).set(lu(l),{mutationKey:l,defaultOptions:i})}getMutationDefaults(l){const i=[...M(this,Zi).values()],s={};return i.forEach(u=>{Ji(l,u.mutationKey)&&Object.assign(s,u.defaultOptions)}),s}defaultQueryOptions(l){if(l._defaulted)return l;const i={...M(this,Yl).queries,...this.getQueryDefaults(l.queryKey),...l,_defaulted:!0};return i.queryHash||(i.queryHash=Qd(i.queryKey,i)),i.refetchOnReconnect===void 0&&(i.refetchOnReconnect=i.networkMode!=="always"),i.throwOnError===void 0&&(i.throwOnError=!!i.suspense),!i.networkMode&&i.persister&&(i.networkMode="offlineFirst"),i.queryFn===Yd&&(i.enabled=!1),i}defaultMutationOptions(l){return l!=null&&l._defaulted?l:{...M(this,Yl).mutations,...(l==null?void 0:l.mutationKey)&&this.getMutationDefaults(l.mutationKey),...l,_defaulted:!0}}clear(){M(this,Je).clear(),M(this,Ql).clear()}},Je=new WeakMap,Ql=new WeakMap,Yl=new WeakMap,Xi=new WeakMap,Zi=new WeakMap,Xl=new WeakMap,Ki=new WeakMap,Ii=new WeakMap,Ay);const Qy=j.createContext(!1),Hb=()=>j.useContext(Qy);Qy.Provider;function Lb(){let l=!1;return{clearReset:()=>{l=!1},reset:()=>{l=!0},isReset:()=>l}}const Vb=j.createContext(Lb()),Bb=()=>j.useContext(Vb),Gb=(l,i,s)=>{const u=(s==null?void 0:s.state.status)==="error"&&typeof l.throwOnError=="function"?Gy(l.throwOnError,[s.state.error,s]):l.throwOnError;(l.suspense||u)&&(i.isReset()||(l.retryOnMount=!1))},qb=l=>{j.useEffect(()=>{l.clearReset()},[l])},Fb=({result:l,errorResetBoundary:i,throwOnError:s,query:u,suspense:c})=>l.isError&&!i.isReset()&&!l.isFetching&&u&&(c&&l.data===void 0||Gy(s,[l.error,u])),$b=l=>{if(l.suspense){const s=c=>c==="static"?c:Math.max(c??1e3,1e3),u=l.staleTime;l.staleTime=typeof u=="function"?(...c)=>s(u(...c)):s(u),typeof l.gcTime=="number"&&(l.gcTime=Math.max(l.gcTime,1e3))}},kb=(l,i)=>(l==null?void 0:l.suspense)&&i.isPending,Qb=(l,i,s)=>i.fetchOptimistic(l).catch(()=>{s.clearReset()});function Yb(l,i,s){const u=Hb(),c=Bb(),f=Dy(),g=f.defaultQueryOptions(l),m=f.getQueryCache().get(g.queryHash),v=l.subscribed!==!1;g._optimisticResults=u?"isRestoring":v?"optimistic":void 0,$b(g),Gb(g,c,m),qb(c);const[S]=j.useState(()=>new i(f,g)),y=S.getOptimisticResult(g),x=!u&&v;if(j.useSyncExternalStore(j.useCallback(C=>{const R=x?S.subscribe(wt.batchCalls(C)):Qt;return S.updateResult(),R},[S,x]),()=>S.getCurrentResult(),()=>S.getCurrentResult()),j.useEffect(()=>{S.setOptions(g)},[g,S]),kb(g,y))throw Qb(g,S,c);if(Fb({result:y,errorResetBoundary:c,throwOnError:g.throwOnError,query:m,suspense:g.suspense}))throw y.error;return g.notifyOnChangeProps?y:S.trackResult(y)}function Wl(l,i){return Yb(l,Mb)}var Xb=Oy();/**
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@@ -55,7 +55,7 @@ Error generating stack: `+a.message+`
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*/function au(){return au=Object.assign?Object.assign.bind():function(l){for(var i=1;i<arguments.length;i++){var s=arguments[i];for(var u in s)({}).hasOwnProperty.call(s,u)&&(l[u]=s[u])}return l},au.apply(null,arguments)}var Zl;(function(l){l.Pop="POP",l.Push="PUSH",l.Replace="REPLACE"})(Zl||(Zl={}));const
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*/function au(){return au=Object.assign?Object.assign.bind():function(l){for(var i=1;i<arguments.length;i++){var s=arguments[i];for(var u in s)({}).hasOwnProperty.call(s,u)&&(l[u]=s[u])}return l},au.apply(null,arguments)}var Zl;(function(l){l.Pop="POP",l.Push="PUSH",l.Replace="REPLACE"})(Zl||(Zl={}));const Zv="popstate";function Zb(l){l===void 0&&(l={});function i(u,c){let{pathname:f,search:g,hash:m}=u.location;return wd("",{pathname:f,search:g,hash:m},c.state&&c.state.usr||null,c.state&&c.state.key||"default")}function s(u,c){return typeof c=="string"?c:Po(c)}return Ib(i,s,null,l)}function st(l,i){if(l===!1||l===null||typeof l>"u")throw new Error(i)}function Yy(l,i){if(!l){typeof console<"u"&&console.warn(i);try{throw new Error(i)}catch{}}}function Kb(){return Math.random().toString(36).substr(2,8)}function Kv(l,i){return{usr:l.state,key:l.key,idx:i}}function wd(l,i,s,u){return s===void 0&&(s=null),au({pathname:typeof l=="string"?l:l.pathname,search:"",hash:""},typeof i=="string"?Wi(i):i,{state:s,key:i&&i.key||u||Kb()})}function Po(l){let{pathname:i="/",search:s="",hash:u=""}=l;return s&&s!=="?"&&(i+=s.charAt(0)==="?"?s:"?"+s),u&&u!=="#"&&(i+=u.charAt(0)==="#"?u:"#"+u),i}function Wi(l){let i={};if(l){let s=l.indexOf("#");s>=0&&(i.hash=l.substr(s),l=l.substr(0,s));let u=l.indexOf("?");u>=0&&(i.search=l.substr(u),l=l.substr(0,u)),l&&(i.pathname=l)}return i}function Ib(l,i,s,u){u===void 0&&(u={});let{window:c=document.defaultView,v5Compat:f=!1}=u,g=c.history,m=Zl.Pop,v=null,S=y();S==null&&(S=0,g.replaceState(au({},g.state,{idx:S}),""));function y(){return(g.state||{idx:null}).idx}function x(){m=Zl.Pop;let b=y(),E=b==null?null:b-S;S=b,v&&v({action:m,location:O.location,delta:E})}function C(b,E){m=Zl.Push;let U=wd(O.location,b,E);S=y()+1;let B=Kv(U,S),$=O.createHref(U);try{g.pushState(B,"",$)}catch(F){if(F instanceof DOMException&&F.name==="DataCloneError")throw F;c.location.assign($)}f&&v&&v({action:m,location:O.location,delta:1})}function R(b,E){m=Zl.Replace;let U=wd(O.location,b,E);S=y();let B=Kv(U,S),$=O.createHref(U);g.replaceState(B,"",$),f&&v&&v({action:m,location:O.location,delta:0})}function _(b){let E=c.location.origin!=="null"?c.location.origin:c.location.href,U=typeof b=="string"?b:Po(b);return U=U.replace(/ $/,"%20"),st(E,"No window.location.(origin|href) available to create URL for href: "+U),new URL(U,E)}let O={get action(){return m},get location(){return l(c,g)},listen(b){if(v)throw new Error("A history only accepts one active listener");return c.addEventListener(Zv,x),v=b,()=>{c.removeEventListener(Zv,x),v=null}},createHref(b){return i(c,b)},createURL:_,encodeLocation(b){let E=_(b);return{pathname:E.pathname,search:E.search,hash:E.hash}},push:C,replace:R,go(b){return g.go(b)}};return O}var Iv;(function(l){l.data="data",l.deferred="deferred",l.redirect="redirect",l.error="error"})(Iv||(Iv={}));function Jb(l,i,s){return s===void 0&&(s="/"),Pb(l,i,s)}function Pb(l,i,s,u){let c=typeof i=="string"?Wi(i):i,f=Id(c.pathname||"/",s);if(f==null)return null;let g=Xy(l);Wb(g);let m=null,v=f2(f);for(let S=0;m==null&&S<g.length;++S)m=o2(g[S],v);return m}function Xy(l,i,s,u){i===void 0&&(i=[]),s===void 0&&(s=[]),u===void 0&&(u="");let c=(f,g,m)=>{let v={relativePath:m===void 0?f.path||"":m,caseSensitive:f.caseSensitive===!0,childrenIndex:g,route:f};v.relativePath.startsWith("/")&&(st(v.relativePath.startsWith(u),'Absolute route path "'+v.relativePath+'" nested under path '+('"'+u+'" is not valid. An absolute child route path ')+"must start with the combined path of all its parent routes."),v.relativePath=v.relativePath.slice(u.length));let S=Il([u,v.relativePath]),y=s.concat(v);f.children&&f.children.length>0&&(st(f.index!==!0,"Index routes must not have child routes. Please remove "+('all child routes from route path "'+S+'".')),Xy(f.children,i,y,S)),!(f.path==null&&!f.index)&&i.push({path:S,score:s2(S,f.index),routesMeta:y})};return l.forEach((f,g)=>{var m;if(f.path===""||!((m=f.path)!=null&&m.includes("?")))c(f,g);else for(let v of Zy(f.path))c(f,g,v)}),i}function Zy(l){let i=l.split("/");if(i.length===0)return[];let[s,...u]=i,c=s.endsWith("?"),f=s.replace(/\?$/,"");if(u.length===0)return c?[f,""]:[f];let g=Zy(u.join("/")),m=[];return m.push(...g.map(v=>v===""?f:[f,v].join("/"))),c&&m.push(...g),m.map(v=>l.startsWith("/")&&v===""?"/":v)}function Wb(l){l.sort((i,s)=>i.score!==s.score?s.score-i.score:u2(i.routesMeta.map(u=>u.childrenIndex),s.routesMeta.map(u=>u.childrenIndex)))}const e2=/^:[\w-]+$/,t2=3,n2=2,l2=1,a2=10,i2=-2,Jv=l=>l==="*";function s2(l,i){let s=l.split("/"),u=s.length;return s.some(Jv)&&(u+=i2),i&&(u+=n2),s.filter(c=>!Jv(c)).reduce((c,f)=>c+(e2.test(f)?t2:f===""?l2:a2),u)}function u2(l,i){return l.length===i.length&&l.slice(0,-1).every((u,c)=>u===i[c])?l[l.length-1]-i[i.length-1]:0}function o2(l,i,s){let{routesMeta:u}=l,c={},f="/",g=[];for(let m=0;m<u.length;++m){let v=u[m],S=m===u.length-1,y=f==="/"?i:i.slice(f.length)||"/",x=r2({path:v.relativePath,caseSensitive:v.caseSensitive,end:S},y),C=v.route;if(!x)return null;Object.assign(c,x.params),g.push({params:c,pathname:Il([f,x.pathname]),pathnameBase:g2(Il([f,x.pathnameBase])),route:C}),x.pathnameBase!=="/"&&(f=Il([f,x.pathnameBase]))}return g}function r2(l,i){typeof l=="string"&&(l={path:l,caseSensitive:!1,end:!0});let[s,u]=c2(l.path,l.caseSensitive,l.end),c=i.match(s);if(!c)return null;let f=c[0],g=f.replace(/(.)\/+$/,"$1"),m=c.slice(1);return{params:u.reduce((S,y,x)=>{let{paramName:C,isOptional:R}=y;if(C==="*"){let O=m[x]||"";g=f.slice(0,f.length-O.length).replace(/(.)\/+$/,"$1")}const _=m[x];return R&&!_?S[C]=void 0:S[C]=(_||"").replace(/%2F/g,"/"),S},{}),pathname:f,pathnameBase:g,pattern:l}}function c2(l,i,s){i===void 0&&(i=!1),s===void 0&&(s=!0),Yy(l==="*"||!l.endsWith("*")||l.endsWith("/*"),'Route path "'+l+'" will be treated as if it were '+('"'+l.replace(/\*$/,"/*")+'" because the `*` character must ')+"always follow a `/` in the pattern. To get rid of this warning, "+('please change the route path to "'+l.replace(/\*$/,"/*")+'".'));let u=[],c="^"+l.replace(/\/*\*?$/,"").replace(/^\/*/,"/").replace(/[\\.*+^${}|()[\]]/g,"\\$&").replace(/\/:([\w-]+)(\?)?/g,(g,m,v)=>(u.push({paramName:m,isOptional:v!=null}),v?"/?([^\\/]+)?":"/([^\\/]+)"));return l.endsWith("*")?(u.push({paramName:"*"}),c+=l==="*"||l==="/*"?"(.*)$":"(?:\\/(.+)|\\/*)$"):s?c+="\\/*$":l!==""&&l!=="/"&&(c+="(?:(?=\\/|$))"),[new RegExp(c,i?void 0:"i"),u]}function f2(l){try{return l.split("/").map(i=>decodeURIComponent(i).replace(/\//g,"%2F")).join("/")}catch(i){return Yy(!1,'The URL path "'+l+'" could not be decoded because it is is a malformed URL segment. This is probably due to a bad percent '+("encoding ("+i+").")),l}}function Id(l,i){if(i==="/")return l;if(!l.toLowerCase().startsWith(i.toLowerCase()))return null;let s=i.endsWith("/")?i.length-1:i.length,u=l.charAt(s);return u&&u!=="/"?null:l.slice(s)||"/"}function d2(l,i){i===void 0&&(i="/");let{pathname:s,search:u="",hash:c=""}=typeof l=="string"?Wi(l):l,f;return s?(s=Jy(s),s.startsWith("/")?f=Pv(s.substring(1),"/"):f=Pv(s,i)):f=i,{pathname:f,search:m2(u),hash:p2(c)}}function Pv(l,i){let s=i.replace(/\/+$/,"").split("/");return l.split("/").forEach(c=>{c===".."?s.length>1&&s.pop():c!=="."&&s.push(c)}),s.length>1?s.join("/"):"/"}function Wf(l,i,s,u){return"Cannot include a '"+l+"' character in a manually specified "+("`to."+i+"` field ["+JSON.stringify(u)+"]. Please separate it out to the ")+("`to."+s+"` field. Alternatively you may provide the full path as ")+'a string in <Link to="..."> and the router will parse it for you.'}function h2(l){return l.filter((i,s)=>s===0||i.route.path&&i.route.path.length>0)}function Ky(l,i){let s=h2(l);return i?s.map((u,c)=>c===s.length-1?u.pathname:u.pathnameBase):s.map(u=>u.pathnameBase)}function Iy(l,i,s,u){u===void 0&&(u=!1);let c;typeof l=="string"?c=Wi(l):(c=au({},l),st(!c.pathname||!c.pathname.includes("?"),Wf("?","pathname","search",c)),st(!c.pathname||!c.pathname.includes("#"),Wf("#","pathname","hash",c)),st(!c.search||!c.search.includes("#"),Wf("#","search","hash",c)));let f=l===""||c.pathname==="",g=f?"/":c.pathname,m;if(g==null)m=s;else{let x=i.length-1;if(!u&&g.startsWith("..")){let C=g.split("/");for(;C[0]==="..";)C.shift(),x-=1;c.pathname=C.join("/")}m=x>=0?i[x]:"/"}let v=d2(c,m),S=g&&g!=="/"&&g.endsWith("/"),y=(f||g===".")&&s.endsWith("/");return!v.pathname.endsWith("/")&&(S||y)&&(v.pathname+="/"),v}const Jy=l=>l.replace(/\/\/+/g,"/"),Il=l=>Jy(l.join("/")),g2=l=>l.replace(/\/+$/,"").replace(/^\/*/,"/"),m2=l=>!l||l==="?"?"":l.startsWith("?")?l:"?"+l,p2=l=>!l||l==="#"?"":l.startsWith("#")?l:"#"+l;function v2(l){return l!=null&&typeof l.status=="number"&&typeof l.statusText=="string"&&typeof l.internal=="boolean"&&"data"in l}const Py=["post","put","patch","delete"];new Set(Py);const y2=["get",...Py];new Set(y2);/**
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*/function iu(){return iu=Object.assign?Object.assign.bind():function(l){for(var i=1;i<arguments.length;i++){var s=arguments[i];for(var u in s)({}).hasOwnProperty.call(s,u)&&(l[u]=s[u])}return l},iu.apply(null,arguments)}const Jd=j.createContext(null),
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*/function iu(){return iu=Object.assign?Object.assign.bind():function(l){for(var i=1;i<arguments.length;i++){var s=arguments[i];for(var u in s)({}).hasOwnProperty.call(s,u)&&(l[u]=s[u])}return l},iu.apply(null,arguments)}const Jd=j.createContext(null),S2=j.createContext(null),Ga=j.createContext(null),ar=j.createContext(null),ea=j.createContext({outlet:null,matches:[],isDataRoute:!1}),Wy=j.createContext(null);function x2(l,i){let{relative:s}=i===void 0?{}:i;hu()||st(!1);let{basename:u,navigator:c}=j.useContext(Ga),{hash:f,pathname:g,search:m}=t0(l,{relative:s}),v=g;return u!=="/"&&(v=g==="/"?u:Il([u,g])),c.createHref({pathname:v,search:m,hash:f})}function hu(){return j.useContext(ar)!=null}function gu(){return hu()||st(!1),j.useContext(ar).location}function e0(l){j.useContext(Ga).static||j.useLayoutEffect(l)}function ir(){let{isDataRoute:l}=j.useContext(ea);return l?D2():b2()}function b2(){hu()||st(!1);let l=j.useContext(Jd),{basename:i,future:s,navigator:u}=j.useContext(Ga),{matches:c}=j.useContext(ea),{pathname:f}=gu(),g=JSON.stringify(Ky(c,s.v7_relativeSplatPath)),m=j.useRef(!1);return e0(()=>{m.current=!0}),j.useCallback(function(S,y){if(y===void 0&&(y={}),!m.current)return;if(typeof S=="number"){u.go(S);return}let x=Iy(S,JSON.parse(g),f,y.relative==="path");l==null&&i!=="/"&&(x.pathname=x.pathname==="/"?i:Il([i,x.pathname])),(y.replace?u.replace:u.push)(x,y.state,y)},[i,u,g,f,l])}function C2(){let{matches:l}=j.useContext(ea),i=l[l.length-1];return i?i.params:{}}function t0(l,i){let{relative:s}=i===void 0?{}:i,{future:u}=j.useContext(Ga),{matches:c}=j.useContext(ea),{pathname:f}=gu(),g=JSON.stringify(Ky(c,u.v7_relativeSplatPath));return j.useMemo(()=>Iy(l,JSON.parse(g),f,s==="path"),[l,g,f,s])}function E2(l,i){return w2(l,i)}function w2(l,i,s,u){hu()||st(!1);let{navigator:c}=j.useContext(Ga),{matches:f}=j.useContext(ea),g=f[f.length-1],m=g?g.params:{};g&&g.pathname;let v=g?g.pathnameBase:"/";g&&g.route;let S=gu(),y;if(i){var x;let b=typeof i=="string"?Wi(i):i;v==="/"||(x=b.pathname)!=null&&x.startsWith(v)||st(!1),y=b}else y=S;let C=y.pathname||"/",R=C;if(v!=="/"){let b=v.replace(/^\//,"").split("/");R="/"+C.replace(/^\//,"").split("/").slice(b.length).join("/")}let _=Jb(l,{pathname:R}),O=M2(_&&_.map(b=>Object.assign({},b,{params:Object.assign({},m,b.params),pathname:Il([v,c.encodeLocation?c.encodeLocation(b.pathname).pathname:b.pathname]),pathnameBase:b.pathnameBase==="/"?v:Il([v,c.encodeLocation?c.encodeLocation(b.pathnameBase).pathname:b.pathnameBase])})),f,s,u);return i&&O?j.createElement(ar.Provider,{value:{location:iu({pathname:"/",search:"",hash:"",state:null,key:"default"},y),navigationType:Zl.Pop}},O):O}function R2(){let l=z2(),i=v2(l)?l.status+" "+l.statusText:l instanceof Error?l.message:JSON.stringify(l),s=l instanceof Error?l.stack:null,c={padding:"0.5rem",backgroundColor:"rgba(200,200,200, 0.5)"};return j.createElement(j.Fragment,null,j.createElement("h2",null,"Unexpected Application Error!"),j.createElement("h3",{style:{fontStyle:"italic"}},i),s?j.createElement("pre",{style:c},s):null,null)}const _2=j.createElement(R2,null);class N2 extends j.Component{constructor(i){super(i),this.state={location:i.location,revalidation:i.revalidation,error:i.error}}static getDerivedStateFromError(i){return{error:i}}static getDerivedStateFromProps(i,s){return s.location!==i.location||s.revalidation!=="idle"&&i.revalidation==="idle"?{error:i.error,location:i.location,revalidation:i.revalidation}:{error:i.error!==void 0?i.error:s.error,location:s.location,revalidation:i.revalidation||s.revalidation}}componentDidCatch(i,s){console.error("React Router caught the following error during render",i,s)}render(){return this.state.error!==void 0?j.createElement(ea.Provider,{value:this.props.routeContext},j.createElement(Wy.Provider,{value:this.state.error,children:this.props.component})):this.props.children}}function T2(l){let{routeContext:i,match:s,children:u}=l,c=j.useContext(Jd);return c&&c.static&&c.staticContext&&(s.route.errorElement||s.route.ErrorBoundary)&&(c.staticContext._deepestRenderedBoundaryId=s.route.id),j.createElement(ea.Provider,{value:i},u)}function M2(l,i,s,u){var c;if(i===void 0&&(i=[]),s===void 0&&(s=null),u===void 0&&(u=null),l==null){var f;if(!s)return null;if(s.errors)l=s.matches;else if((f=u)!=null&&f.v7_partialHydration&&i.length===0&&!s.initialized&&s.matches.length>0)l=s.matches;else return null}let g=l,m=(c=s)==null?void 0:c.errors;if(m!=null){let y=g.findIndex(x=>x.route.id&&(m==null?void 0:m[x.route.id])!==void 0);y>=0||st(!1),g=g.slice(0,Math.min(g.length,y+1))}let v=!1,S=-1;if(s&&u&&u.v7_partialHydration)for(let y=0;y<g.length;y++){let x=g[y];if((x.route.HydrateFallback||x.route.hydrateFallbackElement)&&(S=y),x.route.id){let{loaderData:C,errors:R}=s,_=x.route.loader&&C[x.route.id]===void 0&&(!R||R[x.route.id]===void 0);if(x.route.lazy||_){v=!0,S>=0?g=g.slice(0,S+1):g=[g[0]];break}}}return g.reduceRight((y,x,C)=>{let R,_=!1,O=null,b=null;s&&(R=m&&x.route.id?m[x.route.id]:void 0,O=x.route.errorElement||_2,v&&(S<0&&C===0?(U2("route-fallback"),_=!0,b=null):S===C&&(_=!0,b=x.route.hydrateFallbackElement||null)));let E=i.concat(g.slice(0,C+1)),U=()=>{let B;return R?B=O:_?B=b:x.route.Component?B=j.createElement(x.route.Component,null):x.route.element?B=x.route.element:B=y,j.createElement(T2,{match:x,routeContext:{outlet:y,matches:E,isDataRoute:s!=null},children:B})};return s&&(x.route.ErrorBoundary||x.route.errorElement||C===0)?j.createElement(N2,{location:s.location,revalidation:s.revalidation,component:O,error:R,children:U(),routeContext:{outlet:null,matches:E,isDataRoute:!0}}):U()},null)}var n0=(function(l){return l.UseBlocker="useBlocker",l.UseRevalidator="useRevalidator",l.UseNavigateStable="useNavigate",l})(n0||{}),l0=(function(l){return l.UseBlocker="useBlocker",l.UseLoaderData="useLoaderData",l.UseActionData="useActionData",l.UseRouteError="useRouteError",l.UseNavigation="useNavigation",l.UseRouteLoaderData="useRouteLoaderData",l.UseMatches="useMatches",l.UseRevalidator="useRevalidator",l.UseNavigateStable="useNavigate",l.UseRouteId="useRouteId",l})(l0||{});function j2(l){let i=j.useContext(Jd);return i||st(!1),i}function A2(l){let i=j.useContext(S2);return i||st(!1),i}function O2(l){let i=j.useContext(ea);return i||st(!1),i}function a0(l){let i=O2(),s=i.matches[i.matches.length-1];return s.route.id||st(!1),s.route.id}function z2(){var l;let i=j.useContext(Wy),s=A2(),u=a0();return i!==void 0?i:(l=s.errors)==null?void 0:l[u]}function D2(){let{router:l}=j2(n0.UseNavigateStable),i=a0(l0.UseNavigateStable),s=j.useRef(!1);return e0(()=>{s.current=!0}),j.useCallback(function(c,f){f===void 0&&(f={}),s.current&&(typeof c=="number"?l.navigate(c):l.navigate(c,iu({fromRouteId:i},f)))},[l,i])}const Wv={};function U2(l,i,s){Wv[l]||(Wv[l]=!0)}function H2(l,i){l==null||l.v7_startTransition,l==null||l.v7_relativeSplatPath}function Rd(l){st(!1)}function L2(l){let{basename:i="/",children:s=null,location:u,navigationType:c=Zl.Pop,navigator:f,static:g=!1,future:m}=l;hu()&&st(!1);let v=i.replace(/^\/*/,"/"),S=j.useMemo(()=>({basename:v,navigator:f,static:g,future:iu({v7_relativeSplatPath:!1},m)}),[v,m,f,g]);typeof u=="string"&&(u=Wi(u));let{pathname:y="/",search:x="",hash:C="",state:R=null,key:_="default"}=u,O=j.useMemo(()=>{let b=Id(y,v);return b==null?null:{location:{pathname:b,search:x,hash:C,state:R,key:_},navigationType:c}},[v,y,x,C,R,_,c]);return O==null?null:j.createElement(Ga.Provider,{value:S},j.createElement(ar.Provider,{children:s,value:O}))}function V2(l){let{children:i,location:s}=l;return E2(_d(i),s)}new Promise(()=>{});function _d(l,i){i===void 0&&(i=[]);let s=[];return j.Children.forEach(l,(u,c)=>{if(!j.isValidElement(u))return;let f=[...i,c];if(u.type===j.Fragment){s.push.apply(s,_d(u.props.children,f));return}u.type!==Rd&&st(!1),!u.props.index||!u.props.children||st(!1);let g={id:u.props.id||f.join("-"),caseSensitive:u.props.caseSensitive,element:u.props.element,Component:u.props.Component,index:u.props.index,path:u.props.path,loader:u.props.loader,action:u.props.action,errorElement:u.props.errorElement,ErrorBoundary:u.props.ErrorBoundary,hasErrorBoundary:u.props.ErrorBoundary!=null||u.props.errorElement!=null,shouldRevalidate:u.props.shouldRevalidate,handle:u.props.handle,lazy:u.props.lazy};u.props.children&&(g.children=_d(u.props.children,f)),s.push(g)}),s}/**
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*/const yC=De("ZoomOut",[["circle",{cx:"11",cy:"11",r:"8",key:"4ej97u"}],["line",{x1:"21",x2:"16.65",y1:"21",y2:"16.65",key:"13gj7c"}],["line",{x1:"8",x2:"14",y1:"11",y2:"11",key:"durymu"}]]);function SC(l){if(l.value===null)return l.text??"";switch(l.key){case"coverage":return`${Math.round(l.value)}×`;case"tmb":return l.value<.01?l.value.toPrecision(2):l.value.toFixed(2);default:return l.value.toFixed(2)}}function xC(l){return l.status==="failed"?"Failed":l.status==="skipped"?"Not in this mode":"Not run"}const bC=new Intl.DateTimeFormat("en-GB",{day:"numeric",month:"short",year:"numeric"});function CC(l){if(!l)return"";const i=new Date(l);return Number.isNaN(i.getTime())?"":bC.format(i)}function Wd(l,i){return l.startsWith(`${i}_`)?l.slice(i.length+1):l}function Ad(l){return l==null?"–":l.toFixed(2)}const ny={missense_variant:"Missense",stop_gained:"Nonsense",stop_lost:"Stop lost",start_lost:"Start lost",frameshift_variant:"Frameshift",inframe_deletion:"In-frame 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Chromosome 1 starts at the top and the ring runs clockwise through chromosome 22 to X, each chromosome's arc in proportion to its length (GRCh37).","Copy-number changes are called against the tumour's baseline, its ploidy rounded to whole copies. Very short changes are drawn at a minimum length so they stay visible."],terms:[["Gains (outer track, orange)","Regions with at least one copy more than the baseline."],["Amplifications (outer track, darker and thicker)","Regions with three or more copies above the baseline."],["Losses (inner track, blue)","Regions with at least one copy fewer than the baseline."],["Drivers (black ticks)","Where the tumour's likely driver mutations sit (see the Mutations card for how they are flagged)."]]},{heading:"The sentence",paragraphs:["Written from the same data as the ring: how many amplifications, gains and losses there are and on which chromosomes, and which genes carry driver mutations."]},{heading:"The measurements",paragraphs:["Each tile shows a value, a small picture of where it sits on its scale when it has a natural one, and the analysis it came from. A tile with no value says why: the analysis was not run, it failed, or it does not apply to this kind of report (tumour-only reports have no matched normal)."],terms:[["Purity","The estimated fraction of cells in the sample that are tumour cells, from 0 to 1. The ring fills to the value."],["Ploidy","The tumour's average number of copies across the genome. The scale runs from 1 to 6 copies; the tall tick marks 2, a diploid genome."],["Coverage","The median sequencing depth of the tumour across the genome, in reads (×)."],["TMB per Mb","Tumour mutational burden: somatic SNVs and indels per megabase of genome. The report computes it from the counts of the SNV and indel calls. The scale is logarithmic, 0.01 to 100."],["MSI score","The MSIsensor score: the percentage of microsatellite sites that look unstable in the tumour."],["FGA","Fraction of the genome altered: the share of the genome whose copy number differs from the baseline, from 0 to 1. It is read from the project-wide Battenberg tables."]]},{heading:"Linking back to the analyses",paragraphs:[`Every value names its analysis, with version and Isabl id. Picking an analysis in the side menu's "Analyses on this page" highlights the tiles and cards it feeds.`]}]},copyNumber:{title:"Copy number",intro:"How many copies of each part of the genome the tumour carries, segment by segment, from chromosome 1 to X.",sections:[{heading:"What is drawn",paragraphs:['Each horizontal stroke is one segment: a stretch of the genome with a constant copy number. Its height is the number of copies, from 0 up to 8; anything higher is drawn at the top and the axis reads "8+". Alternating grey bands mark the chromosomes, named along the bottom.',`The dashed line is the baseline: the tumour's ploidy rounded to whole copies (labelled, for example, "2 copies"). Segments are coloured by how they compare with it.`],terms:[["Grey","Neutral: the same number of copies as the baseline."],["Orange","Gain: at least one copy more than the baseline."],["Dark orange","Amplification: three or more copies above the baseline."],["Blue","Loss: at least one copy fewer than the baseline."]]},{heading:"Total or allele-specific",paragraphs:["Total shows all copies together. Allele-specific, when the analysis provides it, splits each segment into its major allele (the more common parental copy, dark) and minor allele (light). Where the two are equal they are drawn slightly apart so both stay visible. A minor allele of 0 means one parent's copy is lost there (loss of heterozygosity)."]},{heading:"Driver genes",paragraphs:["Triangles along the top mark the genes with likely driver mutations, one per gene; hover for its protein changes."]},{heading:"Reading and moving around",terms:[["Hover a segment","Its call, copies (major + minor), coordinates and, when available, log2 ratio."],["Click a segment","Lists the mutations inside it in the Mutations card."],["Click a driver","Finds that gene in the Mutations card."],["Pinch, or Ctrl and scroll","Zooms around the pointer. Plain scrolling always scrolls the page."],["Drag","Pans a zoomed view."],["Double-click a chromosome","Zooms to fill the view with it; the axis then counts megabases."],["Slider and reset","The slider under the plot shows and moves the window; the button by the title returns to the whole genome."],["Hover a mutation in the table","Marks it here, with a ring on the segment it sits on and its copy number."]]},{heading:"Tumour-only reports",paragraphs:["Without a matched normal there is no ploidy estimate, so segments come from CNVkit and are called against two copies. Allele-specific copy numbers are not available."]}]},mutations:{title:"Mutations",intro:"The tumour's somatic SNVs and indels that passed the callers' filters: how they are distributed across cancer cells, and a searchable, filterable table of every call.",sections:[{heading:"Which mutations",terms:[["Drivers","Likely drivers flagged by the report: coding mutations that match OncoKB or COSMIC driver annotations (the exact protein change, or a damaging consequence in a known cancer gene), plus known hotspots the callers missed and the report recovered from the tumour's reads."],["Coding","Mutations whose effect changes a protein, by the report's list of coding effects."],["All","Every PASS SNV and indel."]],paragraphs:["The counts beside each choice follow the search and filters, so they always say what you would see."]},{heading:"FFPE samples",paragraphs:["Formalin-fixed (FFPE) tissue damages DNA in ways that look like mutations, mostly C>T changes at low allele fractions. For an FFPE sample, FFPERASE scores each SNV and indel for how likely it is to be such an artifact, and the report counts only the calls scored at or below its threshold (quoted beside the table). Its SNV, indel and coding totals and the TMB leave the rest out.",`The report marks each call it leaves out, and the dashboard follows that mark: the Coding and All counts, the table and the curve leave those calls out, and the card's subtitle says so. Drivers are all listed, as in the report, and any the filter would remove carry an "FFPE filtered" tag. "Show filtered calls", under FFPE filter beside the table, brings the removed calls back, tagged the same way.`]},{heading:"Cancer cell fraction and variant allele fraction",paragraphs:["The curve across the top is a smoothed histogram of every PASS mutation; driver mutations are labelled on it. Switch between the two measures:"],terms:[["CCF",'Cancer cell fraction: the estimated share of cancer cells carrying the mutation, corrected for purity and copy number. Around 1 (the "clonal" mark) means nearly every cancer cell has it, which suggests it arose early; clearly below 1 means a subclone. Estimates can land somewhat above 1. Shown from 0 to 2.'],["VAF","Variant allele fraction: the share of sequencing reads at the position that carry the mutation, from 0 to 1. Raw, not corrected for purity or copy number. Tumour-only reports open on VAF, since CCF needs a matched normal."]]},{heading:"Filtering by the curve",paragraphs:["Drag across the curve to keep only mutations in that CCF or VAF range; drivers outside it fade. The range appears with the other filters and can be removed there, or by clicking the curve."]},{heading:"The table",terms:[["Gene and position","The gene, and the mutation's chromosome and position (GRCh37)."],["Change","The protein change, with the cDNA change beneath."],["Effect","What the mutation does to the gene, from the VEP consequence (or the report's effect). Truncating effects are in bold."],["VAF and CCF bars","The value with a bar for quick comparison; the CCF bar's tick marks 1, clonal."],["Driver","Flagged as a likely driver (shown when the table is not already limited to drivers)."],["Hotspot","The exact protein change is a known recurrent cancer hotspot."],["In DMP","The same mutation was also found by the patient's clinical MSK-IMPACT (DMP) sequencing."],["FFPE filtered","FFPE samples only: the report's FFPE artifact filter leaves this call out of its counts (see FFPE samples)."]]},{heading:"Opening a row",terms:[["Variant","SNV or indel, with the reference and alternate bases."],["Reads","Reads supporting the mutation out of all reads at the position. Only hotspots the report recovered from the tumour's reads have them; the callers' tables give no single count."],["Normal VAF","The mutation's allele fraction in the matched normal; near 0 for a somatic mutation."],["Mutant copies","How many copies of that part of the genome carry the mutation, out of all copies there."],["Consequence","The full VEP consequence."],["COSMIC","How many samples in COSMIC carry it, and how closely they match (exact change, same position, codon or gene)."],["Expression","The gene's expression in the tumour's RNA, in transcripts per million, when RNA was sequenced."],["Gene role","Whether the gene is a known oncogene or tumour suppressor gene (TSG)."],["Show on copy number","Zooms the Copy number card to the mutation's chromosome and marks it."]]},{heading:"Searching and filtering",paragraphs:["Search takes a gene, a protein or cDNA change, a COSMIC term, or a locus such as chr12:25,398,284 or a range such as chr8:1-50,000,000. Press / anywhere on the page to jump to it. Each filter's count is how many rows you would get by ticking it, given everything else."],terms:[["Missense","One amino acid replaced by another."],["Truncating","Stop gained or lost, start lost, or a frameshift."],["Splice","Changes a splice site or splice region."],["In-frame","Inserts or deletes amino acids without shifting the reading frame."],["Synonymous","Changes the DNA but not the amino acid."],["Other","Everything else, such as intronic, UTR or upstream changes."]]}]},structuralVariants:{title:"Structural variants",intro:"The tumour's rearrangements as the report shows them: those with a breakpoint in an oncogene or tumour suppressor, those that take in a whole gene, and how all of them group into rearrangement signatures.",sections:[{heading:"Which rearrangements",paragraphs:["The report works from the high-confidence structural variants of ANNOT_SVS, which keeps calls made by two or more callers (SvABA, BRASS and GRIDSS) and annotates the genes they touch with AnnotSV. 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{clonal|clonal}`:c.toFixed(2).replace(/0$/,""):c.toFixed(1),rich:{clonal:{color:i.faint,fontFamily:i.font,fontSize:10.5}}},splitLine:{show:!0,lineStyle:{color:i.grid}}},yAxis:{type:"value",show:!1,max:c=>Math.max(1,c.max)*1.25},tooltip:{trigger:"item",...
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Chromosome 1 starts at the top and the ring runs clockwise through chromosome 22 to X, each chromosome's arc in proportion to its length (GRCh37).","Copy-number changes are called against the tumour's baseline, its ploidy rounded to whole copies. Very short changes are drawn at a minimum length so they stay visible."],terms:[["Gains (outer track, orange)","Regions with at least one copy more than the baseline."],["Amplifications (outer track, darker and thicker)","Regions with three or more copies above the baseline."],["Losses (inner track, blue)","Regions with at least one copy fewer than the baseline."],["Drivers (black ticks)","Where the tumour's likely driver mutations sit (see the Mutations card for how they are flagged)."]]},{heading:"The sentence",paragraphs:["Written from the same data as the ring: how many amplifications, gains and losses there are and on which chromosomes, and which genes carry driver mutations."]},{heading:"The measurements",paragraphs:["Each tile shows a value, a small picture of where it sits on its scale when it has a natural one, and the analysis it came from. A tile with no value says why: the analysis was not run, it failed, or it does not apply to this kind of report (tumour-only reports have no matched normal)."],terms:[["Purity","The estimated fraction of cells in the sample that are tumour cells, from 0 to 1. The ring fills to the value."],["Ploidy","The tumour's average number of copies across the genome. The scale runs from 1 to 6 copies; the tall tick marks 2, a diploid genome."],["Coverage","The median sequencing depth of the tumour across the genome, in reads (×)."],["TMB per Mb","Tumour mutational burden: somatic SNVs and indels per megabase of genome. The report computes it from the counts of the SNV and indel calls. The scale is logarithmic, 0.01 to 100."],["MSI score","The MSIsensor score: the percentage of microsatellite sites that look unstable in the tumour."],["FGA","Fraction of the genome altered: the share of the genome whose copy number differs from the baseline, from 0 to 1. It is read from the project-wide Battenberg tables."]]},{heading:"Linking back to the analyses",paragraphs:[`Every value names its analysis, with version and Isabl id. Picking an analysis in the side menu's "Analyses on this page" highlights the tiles and cards it feeds.`]}]},copyNumber:{title:"Copy number",intro:"How many copies of each part of the genome the tumour carries, segment by segment, from chromosome 1 to X.",sections:[{heading:"What is drawn",paragraphs:['Each horizontal stroke is one segment: a stretch of the genome with a constant copy number. Its height is the number of copies, from 0 up to 8; anything higher is drawn at the top and the axis reads "8+". Alternating grey bands mark the chromosomes, named along the bottom.',`The dashed line is the baseline: the tumour's ploidy rounded to whole copies (labelled, for example, "2 copies"). Segments are coloured by how they compare with it.`],terms:[["Grey","Neutral: the same number of copies as the baseline."],["Orange","Gain: at least one copy more than the baseline."],["Dark orange","Amplification: three or more copies above the baseline."],["Blue","Loss: at least one copy fewer than the baseline."]]},{heading:"Total or allele-specific",paragraphs:["Total shows all copies together. Allele-specific, when the analysis provides it, splits each segment into its major allele (the more common parental copy, dark) and minor allele (light). Where the two are equal they are drawn slightly apart so both stay visible. A minor allele of 0 means one parent's copy is lost there (loss of heterozygosity)."]},{heading:"Driver genes",paragraphs:["Triangles along the top mark the genes with likely driver mutations, one per gene; hover for its protein changes."]},{heading:"Reading and moving around",terms:[["Hover a segment","Its call, copies (major + minor), coordinates and, when available, log2 ratio."],["Click a segment","Lists the mutations inside it in the Mutations card."],["Click a driver","Finds that gene in the Mutations card."],["Pinch, or Ctrl and scroll","Zooms around the pointer. Plain scrolling always scrolls the page."],["Drag","Pans a zoomed view."],["Double-click a chromosome","Zooms to fill the view with it; the axis then counts megabases."],["Slider and reset","The slider under the plot shows and moves the window; the button by the title returns to the whole genome."],["Hover a mutation in the table","Marks it here, with a ring on the segment it sits on and its copy number."]]},{heading:"Tumour-only reports",paragraphs:["Without a matched normal there is no ploidy estimate, so segments come from CNVkit and are called against two copies. Allele-specific copy numbers are not available."]}]},mutations:{title:"Mutations",intro:"The tumour's somatic SNVs and indels that passed the callers' filters: how they are distributed across cancer cells, and a searchable, filterable table of every call.",sections:[{heading:"Which mutations",terms:[["Drivers","Likely drivers flagged by the report: coding mutations that match OncoKB or COSMIC driver annotations (the exact protein change, or a damaging consequence in a known cancer gene), plus known hotspots the callers missed and the report recovered from the tumour's reads."],["Coding","Mutations whose effect changes a protein, by the report's list of coding effects."],["All","Every PASS SNV and indel."]],paragraphs:["The counts beside each choice follow the search and filters, so they always say what you would see."]},{heading:"FFPE samples",paragraphs:["Formalin-fixed (FFPE) tissue damages DNA in ways that look like mutations, mostly C>T changes at low allele fractions. For an FFPE sample, FFPERASE scores each SNV and indel for how likely it is to be such an artifact, and the report counts only the calls scored at or below its threshold (quoted beside the table). Its SNV, indel and coding totals and the TMB leave the rest out.",`The report marks each call it leaves out, and the dashboard follows that mark: the Coding and All counts, the table and the curve leave those calls out, and the card's subtitle says so. Drivers are all listed, as in the report, and any the filter would remove carry an "FFPE filtered" tag. "Show filtered calls", under FFPE filter beside the table, brings the removed calls back, tagged the same way.`]},{heading:"Cancer cell fraction and variant allele fraction",paragraphs:["The curve across the top is a smoothed histogram of every PASS mutation; driver mutations are labelled on it. Switch between the two measures:"],terms:[["CCF",'Cancer cell fraction: the estimated share of cancer cells carrying the mutation, corrected for purity and copy number. Around 1 (the "clonal" mark) means nearly every cancer cell has it, which suggests it arose early; clearly below 1 means a subclone. Estimates can land somewhat above 1. Shown from 0 to 2.'],["VAF","Variant allele fraction: the share of sequencing reads at the position that carry the mutation, from 0 to 1. Raw, not corrected for purity or copy number. Tumour-only reports open on VAF, since CCF needs a matched normal."]]},{heading:"Filtering by the curve",paragraphs:["Drag across the curve to keep only mutations in that CCF or VAF range; drivers outside it fade. The range appears with the other filters and can be removed there, or by clicking the curve."]},{heading:"The table",terms:[["Gene and position","The gene, and the mutation's chromosome and position (GRCh37)."],["Change","The protein change, with the cDNA change beneath."],["Effect","What the mutation does to the gene, from the VEP consequence (or the report's effect). Truncating effects are in bold."],["VAF and CCF bars","The value with a bar for quick comparison; the CCF bar's tick marks 1, clonal."],["Driver","Flagged as a likely driver (shown when the table is not already limited to drivers)."],["Hotspot","The exact protein change is a known recurrent cancer hotspot."],["In DMP","The same mutation was also found by the patient's clinical MSK-IMPACT (DMP) sequencing."],["FFPE filtered","FFPE samples only: the report's FFPE artifact filter leaves this call out of its counts (see FFPE samples)."]]},{heading:"Opening a row",terms:[["Variant","SNV or indel, with the reference and alternate bases."],["Reads","Reads supporting the mutation out of all reads at the position. Only hotspots the report recovered from the tumour's reads have them; the callers' tables give no single count."],["Normal VAF","The mutation's allele fraction in the matched normal; near 0 for a somatic mutation."],["Mutant copies","How many copies of that part of the genome carry the mutation, out of all copies there."],["Consequence","The full VEP consequence."],["COSMIC","How many samples in COSMIC carry it, and how closely they match (exact change, same position, codon or gene)."],["Expression","The gene's expression in the tumour's RNA, in transcripts per million, when RNA was sequenced."],["Gene role","Whether the gene is a known oncogene or tumour suppressor gene (TSG)."],["Show on copy number","Zooms the Copy number card to the mutation's chromosome and marks it."]]},{heading:"Searching and filtering",paragraphs:["Search takes a gene, a protein or cDNA change, a COSMIC term, or a locus such as chr12:25,398,284 or a range such as chr8:1-50,000,000. Press / anywhere on the page to jump to it. Each filter's count is how many rows you would get by ticking it, given everything else."],terms:[["Missense","One amino acid replaced by another."],["Truncating","Stop gained or lost, start lost, or a frameshift."],["Splice","Changes a splice site or splice region."],["In-frame","Inserts or deletes amino acids without shifting the reading frame."],["Synonymous","Changes the DNA but not the amino acid."],["Other","Everything else, such as intronic, UTR or upstream changes."]]}]},structuralVariants:{title:"Structural variants",intro:"The tumour's rearrangements as the report shows them: those with a breakpoint in an oncogene or tumour suppressor, those that take in a whole gene, and how all of them group into rearrangement signatures.",sections:[{heading:"Which rearrangements",paragraphs:["The report works from the high-confidence structural variants of ANNOT_SVS, which keeps calls made by two or more callers (SvABA, BRASS and GRIDSS) and annotates the genes they touch with AnnotSV. The count beside the title is how many of these the report counts, its rearrangements total.",`The tables keep the rearrangements whose genes include an oncogene or tumour suppressor, by the report's gene lists. It also searches the callers' raw calls for known rearrangements the high-confidence set can miss, such as CIC fusions, and adds them; a rescued event that is not a two-caller PASS says so in its callers, as in "gridss (CIC rescued)".`]},{heading:"The two tables",terms:[["Rearranged oncogenes and tumour suppressors",'One row per rearrangement and gene it hits, with the gene and breakpoint on each side. A gene near a breakpoint rather than in it is named as the report names it, such as "TERT +/- 100Kb".'],["Whole-gene rearrangements","Rearrangements that take in a whole oncogene or tumour suppressor, from start to end: a deletion of the whole gene, for example."],["Role","Whether the row's genes include an oncogene, a tumour suppressor or both, as the report colours its rows. Click a role above the tables to show only its rows."],["Left and right","Each breakpoint's gene, position (GRCh37) and where it falls in the gene, as AnnotSV writes it (intron5, exon2-exon5). Breakpoints are ordered by chromosome, then position."],["Callers and support","The callers that made the call, and the most reads any of them gives in support."],["Pileups","Supporting reads over all reads at each breakpoint in the tumour's alignments, left then right."],["Expression","For tumours with RNA: whether each gene's expression is high or low against each expression cohort (p63 is cohort project 63): at or above its 90th percentile, at or below its 10th, or neither (None). N/A means the cohort has no value for the gene."]],paragraphs:["Open a row to see both breakpoints, show them on the copy-number card, or copy their IGV loci."]},{heading:"Rearrangement signatures",paragraphs:["WGSPOST groups the tumour's rearrangements the way rearrangement signatures are described: clustered (rearrangements that sit unusually close together, as in chromothripsis) or dispersed, then by class and, except for translocations, by size from under 1 kb to over 1 Mb. Each bar is how many rearrangements fall in a group; lighter bars are the clustered ones.","WGSPOST counts from its own copy of the calls, so its total can differ slightly from the report's rearrangements count."],terms:[["Deletion","A stretch of the genome lost between two breakpoints."],["Tandem duplication","A stretch copied next to itself."],["Inversion","A stretch turned around in place."],["Translocation","A join between two chromosomes."]]}]}},dE={summary:{BATTENBERG:"Tumour purity and ploidy, and the copy-number segments the ring's gains and losses are called from.","BATTENBERG cohort":"Project-wide Battenberg tables, which hold the FGA value and the cohort it is compared with.",CNV_UNMATCHED:"Copy-number segments of a tumour-only report (CNVkit), which the ring's gains and losses are called from.",MOSDEPTH:"The median sequencing coverage.",MSISENSOR:"The MSI score.",MSISENSOR_UNMATCHED:"The MSI score of a tumour-only report.",ANNOT_SNVS:"Somatic SNV calls: their count goes into TMB, and driver SNVs are marked on the ring.",ANNOT_INDELS:"Somatic indel calls: their count goes into TMB, and driver indels are marked on the ring.",ANNOT_SNVS_UNMATCHED:"Tumour-only SNV calls: their count goes into TMB, and driver SNVs are marked on the ring.",ANNOT_INDELS_UNMATCHED:"Tumour-only indel calls: their count goes into TMB, and driver indels are marked on the ring.",WGSPOST:"Cancer cell fractions of the mutations, read together with the driver calls marked on the ring."},copyNumber:{BATTENBERG:"Every segment drawn: total copies, major and minor allele copies, and the ploidy the baseline is rounded from.","BATTENBERG cohort":"Project-wide Battenberg tables the report reads alongside this run; they hold the FGA, and are not drawn here.",CNV_UNMATCHED:"The segments of a tumour-only report (CNVkit), drawn against two copies."},mutations:{ANNOT_SNVS:"The tumour's PASS somatic SNVs and their annotation: gene, protein and cDNA change, effect, VAF, read counts, normal VAF and COSMIC.",ANNOT_INDELS:"The tumour's PASS somatic indels and their annotation, as for SNVs.",ANNOT_SNVS_UNMATCHED:"Tumour-only SNV calls and their annotation.",ANNOT_INDELS_UNMATCHED:"Tumour-only indel calls and their annotation.",WGSPOST:"Each mutation's cancer cell fraction (CCF) and how many copies carry it.",BATTENBERG:"Ploidy, which fills in the copy count where WGSPOST has none, and purity, which gives a CCF to hotspots recovered from the tumour's reads.",FFPERASE_SNVS:"FFPE samples: each SNV's artifact score. 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{clonal|clonal}`:c.toFixed(2).replace(/0$/,""):c.toFixed(1),rich:{clonal:{color:i.faint,fontFamily:i.font,fontSize:10.5}}},splitLine:{show:!0,lineStyle:{color:i.grid}}},yAxis:{type:"value",show:!1,max:c=>Math.max(1,c.max)*1.25},tooltip:{trigger:"item",...nh(i)},brush:{xAxisIndex:0,seriesIndex:[ZE],brushType:"lineX",brushMode:"single",transformable:!0,removeOnClick:!0,brushStyle:{color:Bl(i.accent,.08),borderColor:Bl(i.accent,.55),borderWidth:1},outOfBrush:{colorAlpha:.25},throttleType:"debounce",throttleDelay:120},series:[{id:"density",type:"line",name:u,data:s,smooth:.45,symbol:"none",silent:!0,lineStyle:{width:2.25,color:i.ccfLine},areaStyle:{color:{type:"linear",x:0,y:0,x2:0,y2:1,colorStops:[{offset:0,color:Bl(i.ccfFill,.26)},{offset:1,color:Bl(i.ccfFill,.02)}]}},markLine:l.measure==="ccf"?{silent:!0,symbol:"none",animation:!1,lineStyle:{color:i.axis,type:[4,4],width:1.25},label:{show:!1},data:[{xAxis:1}]}:void 0},{id:"drivers",type:"scatter",name:"Drivers",data:[...l.drivers].sort((c,f)=>c.value-f.value).map(c=>({value:[Ld(l,c.value),L0(s,Ld(l,c.value))],name:c.gene??"?",protein:c.protein_change,actual:c.value})),symbolSize:10,cursor:"pointer",itemStyle:{opacity:1,color:i.dot,borderColor:i.card,borderWidth:2.5,shadowBlur:6,shadowColor:Bl(i.dot,.3)},emphasis:{scale:1.5},label:{show:!0,formatter:"{b}",position:"top",distance:10,color:i.ink,fontWeight:600,fontStyle:"italic",fontSize:11.5},labelLine:{show:!0,lineStyle:{color:i.axis,width:1}},labelLayout:A0({top:4}),tooltip:{formatter:c=>`<span style="font-weight:600"><i>${c.name}</i></span> ${c.data.protein??""}<div style="margin-top:3px">${u} <span style="font-weight:600">${c.data.actual.toFixed(2)}</span></div><div style="opacity:.7;font-size:11.5px;margin-top:5px">Driver. Click to find it in the table</div>`},z:4},{id:"focus",type:"scatter",data:[],silent:!0,symbolSize:13,itemStyle:{opacity:1,color:i.card,borderColor:i.ink,borderWidth:2.5},label:{show:!0,position:"right",distance:8,color:i.ink,fontSize:11,fontWeight:600,backgroundColor:i.card,borderColor:i.line,borderWidth:1,borderRadius:6,padding:[3,6]},markLine:{silent:!0,symbol:"none",animation:!1,lineStyle:{color:i.ink,type:"solid",width:1.25,opacity:.45},label:{show:!1},data:[]},animation:!1,z:6}]}}function IE(l,i){const s=i?l.measure==="ccf"?i.ccf:i.vaf:null;if(s==null)return{series:[{id:"focus",data:[],markLine:{data:[]}}]};const u=Ld(l,s),c=L0(H0(l),u);return{series:[{id:"focus",data:[{value:[u,c],label:{formatter:`${(i==null?void 0:i.gene)??"?"} ${s.toFixed(2)}`}}],markLine:{data:[[{coord:[u,0]},{coord:[u,c]}]]}}]}}function gy(l,i){l.dispatchAction({type:"takeGlobalCursor",key:"brush",brushOption:{brushType:"lineX",brushMode:"single"}}),l.dispatchAction({type:"brush",areas:i?[{brushType:"lineX",xAxisIndex:0,coordRange:i}]:[]})}const my=l=>Math.round(l*100)/100;function JE({data:l,range:i,focus:s,onRange:u,onGene:c}){const[f,g]=ah(),m=j.useRef(null),v=j.useRef(i);v.current=i;const S=j.useMemo(()=>g?KE(l,g):null,[l,g]),y=j.useMemo(()=>IE(l,s),[l,s]),x=j.useMemo(()=>({brushEnd:O=>{const b=O.areas[0];if(!b)return u(null);const[E,U]=b.coordRange;u(U-E<.005?null:[my(E),my(U)])},click:O=>{O.seriesId==="drivers"&&O.name&&c(O.name)}}),[u,c]),C=j.useCallback(O=>(m.current=O,()=>{m.current=null}),[]),R=j.useCallback(O=>gy(O,v.current),[]);j.useEffect(()=>{m.current&&gy(m.current,i)},[i]);const _=V0(l.measure);return d.jsx("div",{ref:f,className:"strip-chart",children:S&&d.jsx(lh,{option:S,overlay:y,height:196,ariaLabel:`${_} of ${l.total} variants in ${l.sample}${l.drivers.length?`, with ${l.drivers.map(O=>`${O.gene} at ${O.value.toFixed(2)}`).join(", ")}`:""}.`,onEvents:x,onReady:C,onDrawn:R})})}function PE({envelope:l,loading:i,measure:s,onMeasure:u,range:c,focus:f,onRange:g,onGene:m}){const v=s==="ccf"?"Cancer cell fraction":"Variant allele fraction",S=(l==null?void 0:l.status)==="ok"?l.data:null;return d.jsxs("div",{className:"strip",children:[d.jsxs("div",{className:"strip-head",children:[d.jsx("span",{className:"text-[13px] font-semibold",children:v}),S&&d.jsxs("span",{className:"text-[12.5px]",style:{color:"var(--muted)"},children:[S.median!==null?`Median ${S.median.toFixed(2)}. `:"","Drag across the plot to filter the table."]}),d.jsx("span",{className:"flex-auto"}),d.jsx(hr,{label:"Measure",value:s,onChange:u,options:[{value:"ccf",label:"CCF"},{value:"vaf",label:"VAF"}]})]}),d.jsx(dr,{label:v,envelope:l,loading:i,skeletonHeight:180,children:y=>d.jsx(JE,{data:y,range:c,focus:f,onRange:g,onGene:m})})]})}const WE=Object.keys(C0),ew=Object.keys(E0);function py(l,i){return l.includes(i)?l.filter(s=>s!==i):[...l,i]}function ld({label:l,count:i,active:s,onClick:u}){return d.jsxs("button",{type:"button",className:"facet","aria-pressed":s,"data-empty":!s&&i===0,onClick:u,children:[d.jsx("span",{className:"facet-check","aria-hidden":!0,children:s&&d.jsx(sC,{size:11,strokeWidth:3})}),d.jsx("span",{className:"truncate",children:l}),d.jsx("span",{className:"facet-n",children:i===void 0?"":i.toLocaleString("en-US")})]})}function tw({table:l,data:i,onChange:s}){const u=i==null?void 0:i.facets.effects,c=i==null?void 0:i.facets.flags,f=l.range;return d.jsxs("aside",{className:"facets","aria-label":"Filters",children:[d.jsxs("div",{className:"facet-group",role:"group","aria-label":"Effect",children:[d.jsx("span",{className:"facet-title",children:"Effect"}),WE.map(g=>d.jsx(ld,{label:C0[g],count:u==null?void 0:u[g],active:l.effects.includes(g),onClick:()=>s({effects:py(l.effects,g)})},g))]}),d.jsxs("div",{className:"facet-group",role:"group","aria-label":"Flags",children:[d.jsx("span",{className:"facet-title",children:"Flags"}),ew.map(g=>d.jsx(ld,{label:E0[g],count:c==null?void 0:c[g],active:l.flags.includes(g),onClick:()=>s({flags:py(l.flags,g)})},g))]}),(i==null?void 0:i.ffpe)&&d.jsxs("div",{className:"facet-group",role:"group","aria-label":"FFPE filter",children:[d.jsx("span",{className:"facet-title",children:"FFPE filter"}),d.jsx(ld,{label:"Show filtered calls",count:i.ffpe.removed,active:l.ffpe,onClick:()=>s({ffpe:!l.ffpe})}),d.jsx("span",{className:"facet-note",children:i.ffpe.threshold!==null?`As in the report, calls FFPERASE scores above ${i.ffpe.threshold} are left out of the counts.`:"As in the report, calls its FFPE filter removes are left out of the counts."})]}),f&&d.jsxs("div",{className:"facet-group",role:"group","aria-label":"Range",children:[d.jsxs("span",{className:"facet-title",children:[f.measure==="ccf"?"CCF":"VAF"," range"]}),d.jsxs("span",{className:"facet-range",children:[d.jsxs("span",{className:"mono",children:[f.low.toFixed(2)," – ",f.high.toFixed(2)]}),d.jsx("button",{type:"button",className:"sc-ib xs","aria-label":"Remove the range",title:"Remove the range",onClick:()=>s({range:null}),children:d.jsx(Pd,{size:13,"aria-hidden":!0})})]})]}),b0(l)>0&&d.jsx("button",{type:"button",className:"facet-clear",onClick:()=>s({q:"",effects:[],flags:[],range:null}),children:"Clear all filters"})]})}function nw({value:l,onChange:i}){const[s,u]=j.useState(l),c=j.useRef(null),f=j.useRef(i);f.current=i,j.useEffect(()=>u(l),[l]),j.useEffect(()=>{if(s===l)return;const m=window.setTimeout(()=>f.current(s),250);return()=>window.clearTimeout(m)},[s,l]),j.useEffect(()=>{const m=v=>{var S,y,x;v.key!=="/"||v.metaKey||v.ctrlKey||v.altKey||(y=(S=v.target)==null?void 0:S.closest)!=null&&y.call(S,"input, textarea, select, [contenteditable]")||(v.preventDefault(),(x=c.current)==null||x.focus())};return document.addEventListener("keydown",m),()=>document.removeEventListener("keydown",m)},[]);const g=()=>{u(""),i("")};return d.jsxs("div",{className:"field search-field",children:[d.jsx(ur,{size:15,"aria-hidden":!0,style:{color:"var(--chev)"}}),d.jsx("input",{ref:c,type:"search","aria-label":"Search mutations",placeholder:"Search gene, change or locus",value:s,onChange:m=>u(m.target.value),onKeyDown:m=>{m.key==="Escape"&&g(),m.key==="Enter"&&i(s)}}),s?d.jsx("button",{type:"button",className:"search-clear","aria-label":"Clear the search",onClick:g,children:d.jsx(Pd,{size:14,"aria-hidden":!0})}):d.jsx("kbd",{className:"kbd","aria-hidden":!0,children:"/"})]})}/**
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*/function Kl(l,i){return typeof l=="function"?l(i):l}function ln(l,i){return s=>{i.setState(u=>({...u,[l]:Kl(s,u[l])}))}}function gr(l){return l instanceof Function}function
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*/function Kl(l,i){return typeof l=="function"?l(i):l}function ln(l,i){return s=>{i.setState(u=>({...u,[l]:Kl(s,u[l])}))}}function gr(l){return l instanceof Function}function lw(l){return Array.isArray(l)&&l.every(i=>typeof i=="number")}function aw(l,i){const s=[],u=c=>{c.forEach(f=>{s.push(f);const g=i(f);g!=null&&g.length&&u(g)})};return u(l),s}function ce(l,i,s){let u=[],c;return f=>{let g;s.key&&s.debug&&(g=Date.now());const m=l(f);if(!(m.length!==u.length||m.some((y,x)=>u[x]!==y)))return c;u=m;let S;if(s.key&&s.debug&&(S=Date.now()),c=i(...m),s==null||s.onChange==null||s.onChange(c),s.key&&s.debug&&s!=null&&s.debug()){const y=Math.round((Date.now()-g)*100)/100,x=Math.round((Date.now()-S)*100)/100,C=x/16,R=(_,O)=>{for(_=String(_);_.length<O;)_=" "+_;return _};console.info(`%c⏱ ${R(x,5)} /${R(y,5)} ms`,`
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color: hsl(${Math.max(0,Math.min(120-120*b,120))}deg 100% 31%);`,s==null?void 0:s.key)}return c}}function fe(l,i,s,u){return{debug:()=>{var c;return(c=l==null?void 0:l.debugAll)!=null?c:l[i]},key:!1,onChange:u}}function aw(l,i,s,u){const c=()=>{var g;return(g=f.getValue())!=null?g:l.options.renderFallbackValue},f={id:`${i.id}_${s.id}`,row:i,column:s,getValue:()=>i.getValue(u),renderValue:c,getContext:ce(()=>[l,s,i,f],(g,m,y,x)=>({table:g,column:m,row:y,cell:x,getValue:x.getValue,renderValue:x.renderValue}),fe(l.options,"debugCells"))};return l._features.forEach(g=>{g.createCell==null||g.createCell(f,s,i,l)},{}),f}function iw(l,i,s,u){var c,f;const m={...l._getDefaultColumnDef(),...i},y=m.accessorKey;let x=(c=(f=m.id)!=null?f:y?typeof String.prototype.replaceAll=="function"?y.replaceAll(".","_"):y.replace(/\./g,"_"):void 0)!=null?c:typeof m.header=="string"?m.header:void 0,v;if(m.accessorFn?v=m.accessorFn:y&&(y.includes(".")?v=b=>{let N=b;for(const D of y.split(".")){var 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Yo(i,f,l,"right")},fe(l.options,Nt)),l.getFooterGroups=ce(()=>[l.getHeaderGroups()],i=>[...i].reverse(),fe(l.options,Nt)),l.getLeftFooterGroups=ce(()=>[l.getLeftHeaderGroups()],i=>[...i].reverse(),fe(l.options,Nt)),l.getCenterFooterGroups=ce(()=>[l.getCenterHeaderGroups()],i=>[...i].reverse(),fe(l.options,Nt)),l.getRightFooterGroups=ce(()=>[l.getRightHeaderGroups()],i=>[...i].reverse(),fe(l.options,Nt)),l.getFlatHeaders=ce(()=>[l.getHeaderGroups()],i=>i.map(s=>s.headers).flat(),fe(l.options,Nt)),l.getLeftFlatHeaders=ce(()=>[l.getLeftHeaderGroups()],i=>i.map(s=>s.headers).flat(),fe(l.options,Nt)),l.getCenterFlatHeaders=ce(()=>[l.getCenterHeaderGroups()],i=>i.map(s=>s.headers).flat(),fe(l.options,Nt)),l.getRightFlatHeaders=ce(()=>[l.getRightHeaderGroups()],i=>i.map(s=>s.headers).flat(),fe(l.options,Nt)),l.getCenterLeafHeaders=ce(()=>[l.getCenterFlatHeaders()],i=>i.filter(s=>{var 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s,u,c;return(s=i.options.getRowCanExpand==null?void 0:i.options.getRowCanExpand(l))!=null?s:((u=i.options.enableExpanding)!=null?u:!0)&&!!((c=l.subRows)!=null&&c.length)},l.getIsAllParentsExpanded=()=>{let s=!0,u=l;for(;s&&u.parentId;)u=i.getRow(u.parentId,!0),s=u.getIsExpanded();return s},l.getToggleExpandedHandler=()=>{const s=l.getCanExpand();return()=>{s&&l.toggleExpanded()}}}},Vd=0,Bd=10,od=()=>({pageIndex:Vd,pageSize:Bd}),jw={getInitialState:l=>({...l,pagination:{...od(),...l==null?void 0:l.pagination}}),getDefaultOptions:l=>({onPaginationChange:ln("pagination",l)}),createTable:l=>{let i=!1,s=!1;l._autoResetPageIndex=()=>{var u,c;if(!i){l._queue(()=>{i=!0});return}if((u=(c=l.options.autoResetAll)!=null?c:l.options.autoResetPageIndex)!=null?u:!l.options.manualPagination){if(s)return;s=!0,l._queue(()=>{l.resetPageIndex(),s=!1})}},l.setPagination=u=>{const c=f=>Kl(u,f);return l.options.onPaginationChange==null?void 0:l.options.onPaginationChange(c)},l.resetPagination=u=>{var c;l.setPagination(u?od():(c=l.initialState.pagination)!=null?c:od())},l.setPageIndex=u=>{l.setPagination(c=>{let f=Kl(u,c.pageIndex);const g=typeof l.options.pageCount>"u"||l.options.pageCount===-1?Number.MAX_SAFE_INTEGER:l.options.pageCount-1;return f=Math.max(0,Math.min(f,g)),{...c,pageIndex:f}})},l.resetPageIndex=u=>{var c,f;l.setPageIndex(u?Vd:(c=(f=l.initialState)==null||(f=f.pagination)==null?void 0:f.pageIndex)!=null?c:Vd)},l.resetPageSize=u=>{var c,f;l.setPageSize(u?Bd:(c=(f=l.initialState)==null||(f=f.pagination)==null?void 0:f.pageSize)!=null?c:Bd)},l.setPageSize=u=>{l.setPagination(c=>{const f=Math.max(1,Kl(u,c.pageSize)),g=c.pageSize*c.pageIndex,m=Math.floor(g/f);return{...c,pageIndex:m,pageSize:f}})},l.setPageCount=u=>l.setPagination(c=>{var f;let g=Kl(u,(f=l.options.pageCount)!=null?f:-1);return typeof g=="number"&&(g=Math.max(-1,g)),{...c,pageCount:g}}),l.getPageOptions=ce(()=>[l.getPageCount()],u=>{let c=[];return u&&u>0&&(c=[...new 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i.filter(f=>!c.has(f.id))},fe(l.options,"debugRows"))}},Ow={getInitialState:l=>({rowSelection:{},...l}),getDefaultOptions:l=>({onRowSelectionChange:ln("rowSelection",l),enableRowSelection:!0,enableMultiRowSelection:!0,enableSubRowSelection:!0}),createTable:l=>{l.setRowSelection=i=>l.options.onRowSelectionChange==null?void 0:l.options.onRowSelectionChange(i),l.resetRowSelection=i=>{var s;return l.setRowSelection(i?{}:(s=l.initialState.rowSelection)!=null?s:{})},l.toggleAllRowsSelected=i=>{l.setRowSelection(s=>{i=typeof i<"u"?i:!l.getIsAllRowsSelected();const u={...s},c=l.getPreGroupedRowModel().flatRows;return i?c.forEach(f=>{f.getCanSelect()&&(u[f.id]=!0)}):c.forEach(f=>{delete u[f.id]}),u})},l.toggleAllPageRowsSelected=i=>l.setRowSelection(s=>{const u=typeof i<"u"?i:!l.getIsAllPageRowsSelected(),c={...s};return 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u=!!i.length;return u&&i.some(c=>!s[c.id])&&(u=!1),u},l.getIsSomeRowsSelected=()=>{var i;const s=Object.keys((i=l.getState().rowSelection)!=null?i:{}).length;return s>0&&s<l.getFilteredRowModel().flatRows.length},l.getIsSomePageRowsSelected=()=>{const i=l.getPaginationRowModel().flatRows;return l.getIsAllPageRowsSelected()?!1:i.filter(s=>s.getCanSelect()).some(s=>s.getIsSelected()||s.getIsSomeSelected())},l.getToggleAllRowsSelectedHandler=()=>i=>{l.toggleAllRowsSelected(i.target.checked)},l.getToggleAllPageRowsSelectedHandler=()=>i=>{l.toggleAllPageRowsSelected(i.target.checked)}},createRow:(l,i)=>{l.toggleSelected=(s,u)=>{const c=l.getIsSelected();i.setRowSelection(f=>{var g;if(s=typeof s<"u"?s:!c,l.getCanSelect()&&c===s)return f;const m={...f};return Gd(m,l.id,s,(g=u==null?void 0:u.selectChildren)!=null?g:!0,i),m})},l.getIsSelected=()=>{const{rowSelection:s}=i.getState();return ih(l,s)},l.getIsSomeSelected=()=>{const{rowSelection:s}=i.getState();return qd(l,s)==="some"},l.getIsAllSubRowsSelected=()=>{const{rowSelection:s}=i.getState();return qd(l,s)==="all"},l.getCanSelect=()=>{var s;return typeof i.options.enableRowSelection=="function"?i.options.enableRowSelection(l):(s=i.options.enableRowSelection)!=null?s:!0},l.getCanSelectSubRows=()=>{var s;return typeof i.options.enableSubRowSelection=="function"?i.options.enableSubRowSelection(l):(s=i.options.enableSubRowSelection)!=null?s:!0},l.getCanMultiSelect=()=>{var s;return typeof i.options.enableMultiRowSelection=="function"?i.options.enableMultiRowSelection(l):(s=i.options.enableMultiRowSelection)!=null?s:!0},l.getToggleSelectedHandler=()=>{const s=l.getCanSelect();return u=>{var c;s&&l.toggleSelected((c=u.target)==null?void 0:c.checked)}}}},Gd=(l,i,s,u,c)=>{var f;const g=c.getRow(i,!0);s?(g.getCanMultiSelect()||Object.keys(l).forEach(m=>delete l[m]),g.getCanSelect()&&(l[i]=!0)):delete 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Fd=/([0-9]+)/gm,zw=(l,i,s)=>Q0(Pl(l.getValue(s)).toLowerCase(),Pl(i.getValue(s)).toLowerCase()),Dw=(l,i,s)=>Q0(Pl(l.getValue(s)),Pl(i.getValue(s))),Uw=(l,i,s)=>sh(Pl(l.getValue(s)).toLowerCase(),Pl(i.getValue(s)).toLowerCase()),Hw=(l,i,s)=>sh(Pl(l.getValue(s)),Pl(i.getValue(s))),Lw=(l,i,s)=>{const u=l.getValue(s),c=i.getValue(s);return u>c?1:u<c?-1:0},Vw=(l,i,s)=>sh(l.getValue(s),i.getValue(s));function sh(l,i){return l===i?0:l>i?1:-1}function Pl(l){return typeof l=="number"?isNaN(l)||l===1/0||l===-1/0?"":String(l):typeof l=="string"?l:""}function Q0(l,i){const s=l.split(Fd).filter(Boolean),u=i.split(Fd).filter(Boolean);for(;s.length&&u.length;){const c=s.shift(),f=u.shift(),g=parseInt(c,10),m=parseInt(f,10),y=[g,m].sort();if(isNaN(y[0])){if(c>f)return 1;if(f>c)return-1;continue}if(isNaN(y[1]))return isNaN(g)?-1:1;if(g>m)return 1;if(m>g)return-1}return s.length-u.length}const Ws={alphanumeric:zw,alphanumericCaseSensitive:Dw,text:Uw,textCaseSensitive:Hw,datetime:Lw,basic:Vw},Bw={getInitialState:l=>({sorting:[],...l}),getDefaultColumnDef:()=>({sortingFn:"auto",sortUndefined:1}),getDefaultOptions:l=>({onSortingChange:ln("sorting",l),isMultiSortEvent:i=>i.shiftKey}),createColumn:(l,i)=>{l.getAutoSortingFn=()=>{const s=i.getFilteredRowModel().flatRows.slice(10);let u=!1;for(const c of s){const f=c==null?void 0:c.getValue(l.id);if(Object.prototype.toString.call(f)==="[object Date]")return Ws.datetime;if(typeof f=="string"&&(u=!0,f.split(Fd).length>1))return Ws.alphanumeric}return u?Ws.text:Ws.basic},l.getAutoSortDir=()=>{const s=i.getFilteredRowModel().flatRows[0];return typeof(s==null?void 0:s.getValue(l.id))=="string"?"asc":"desc"},l.getSortingFn=()=>{var s,u;if(!l)throw new Error;return gr(l.columnDef.sortingFn)?l.columnDef.sortingFn:l.columnDef.sortingFn==="auto"?l.getAutoSortingFn():(s=(u=i.options.sortingFns)==null?void 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g?g!==f&&((u=i.options.enableSortingRemoval)==null||u)&&(!(s&&(c=i.options.enableMultiRemove)!=null)||c)?!1:g==="desc"?"asc":"desc":f},l.getCanSort=()=>{var s,u;return((s=l.columnDef.enableSorting)!=null?s:!0)&&((u=i.options.enableSorting)!=null?u:!0)&&!!l.accessorFn},l.getCanMultiSort=()=>{var s,u;return(s=(u=l.columnDef.enableMultiSort)!=null?u:i.options.enableMultiSort)!=null?s:!!l.accessorFn},l.getIsSorted=()=>{var s;const u=(s=i.getState().sorting)==null?void 0:s.find(c=>c.id===l.id);return u?u.desc?"desc":"asc":!1},l.getSortIndex=()=>{var s,u;return(s=(u=i.getState().sorting)==null?void 0:u.findIndex(c=>c.id===l.id))!=null?s:-1},l.clearSorting=()=>{i.setSorting(s=>s!=null&&s.length?s.filter(u=>u.id!==l.id):[])},l.getToggleSortingHandler=()=>{const s=l.getCanSort();return u=>{s&&(u.persist==null||u.persist(),l.toggleSorting==null||l.toggleSorting(void 0,l.getCanMultiSort()?i.options.isMultiSortEvent==null?void 0:i.options.isMultiSortEvent(u):!1))}}},createTable:l=>{l.setSorting=i=>l.options.onSortingChange==null?void 0:l.options.onSortingChange(i),l.resetSorting=i=>{var s,u;l.setSorting(i?[]:(s=(u=l.initialState)==null?void 0:u.sorting)!=null?s:[])},l.getPreSortedRowModel=()=>l.getGroupedRowModel(),l.getSortedRowModel=()=>(!l._getSortedRowModel&&l.options.getSortedRowModel&&(l._getSortedRowModel=l.options.getSortedRowModel(l)),l.options.manualSorting||!l._getSortedRowModel?l.getPreSortedRowModel():l._getSortedRowModel())}},Gw=[sw,Rw,bw,Cw,ow,rw,Nw,Tw,Bw,Sw,Mw,jw,Aw,Ow,ww];function qw(l){var i,s;const u=[...Gw,...(i=l._features)!=null?i:[]];let c={_features:u};const f=c._features.reduce((b,N)=>Object.assign(b,N.getDefaultOptions==null?void 0:N.getDefaultOptions(c)),{}),g=b=>c.options.mergeOptions?c.options.mergeOptions(f,b):{...f,...b};let y={...{},...(s=l.initialState)!=null?s:{}};c._features.forEach(b=>{var N;y=(N=b.getInitialState==null?void 0:b.getInitialState(y))!=null?N:y});const x=[];let v=!1;const S={_features:u,options:{...f,...l},initialState:y,_queue:b=>{x.push(b),v||(v=!0,Promise.resolve().then(()=>{for(;x.length;)x.shift()();v=!1}).catch(N=>setTimeout(()=>{throw N})))},reset:()=>{c.setState(c.initialState)},setOptions:b=>{const N=Kl(b,c.options);c.options=g(N)},getState:()=>c.options.state,setState:b=>{c.options.onStateChange==null||c.options.onStateChange(b)},_getRowId:(b,N,E)=>{var D;return(D=c.options.getRowId==null?void 0:c.options.getRowId(b,N,E))!=null?D:`${E?[E.id,N].join("."):N}`},getCoreRowModel:()=>(c._getCoreRowModel||(c._getCoreRowModel=c.options.getCoreRowModel(c)),c._getCoreRowModel()),getRowModel:()=>c.getPaginationRowModel(),getRow:(b,N)=>{let E=(N?c.getPrePaginationRowModel():c.getRowModel()).rowsById[b];if(!E&&(E=c.getCoreRowModel().rowsById[b],!E))throw new Error;return E},_getDefaultColumnDef:ce(()=>[c.options.defaultColumn],b=>{var N;return b=(N=b)!=null?N:{},{header:E=>{const D=E.header.column.columnDef;return D.accessorKey?D.accessorKey:D.accessorFn?D.id:null},cell:E=>{var D,_;return(D=(_=E.renderValue())==null||_.toString==null?void 0:_.toString())!=null?D:null},...c._features.reduce((E,D)=>Object.assign(E,D.getDefaultColumnDef==null?void 0:D.getDefaultColumnDef()),{}),...b}},fe(l,"debugColumns")),_getColumnDefs:()=>c.options.columns,getAllColumns:ce(()=>[c._getColumnDefs()],b=>{const N=function(E,D,_){return _===void 0&&(_=0),E.map(C=>{const U=iw(c,C,_,D),B=C;return U.columns=B.columns?N(B.columns,U,_+1):[],U})};return N(b)},fe(l,"debugColumns")),getAllFlatColumns:ce(()=>[c.getAllColumns()],b=>b.flatMap(N=>N.getFlatColumns()),fe(l,"debugColumns")),_getAllFlatColumnsById:ce(()=>[c.getAllFlatColumns()],b=>b.reduce((N,E)=>(N[E.id]=E,N),{}),fe(l,"debugColumns")),getAllLeafColumns:ce(()=>[c.getAllColumns(),c._getOrderColumnsFn()],(b,N)=>{let E=b.flatMap(D=>D.getLeafColumns());return N(E)},fe(l,"debugColumns")),getColumn:b=>c._getAllFlatColumnsById()[b]};Object.assign(c,S);for(let b=0;b<c._features.length;b++){const N=c._features[b];N==null||N.createTable==null||N.createTable(c)}return c}function Y0(){return l=>ce(()=>[l.options.data],i=>{const s={rows:[],flatRows:[],rowsById:{}},u=function(c,f,g){f===void 0&&(f=0);const m=[];for(let x=0;x<c.length;x++){const v=uw(l,l._getRowId(c[x],x,g),c[x],x,f,void 0,g==null?void 0:g.id);if(s.flatRows.push(v),s.rowsById[v.id]=v,m.push(v),l.options.getSubRows){var y;v.originalSubRows=l.options.getSubRows(c[x],x),(y=v.originalSubRows)!=null&&y.length&&(v.subRows=u(v.originalSubRows,f+1,v))}}return m};return s.rows=u(i),s},fe(l.options,"debugTable","getRowModel",()=>l._autoResetPageIndex()))}function X0(){return l=>ce(()=>[l.getState().expanded,l.getPreExpandedRowModel(),l.options.paginateExpandedRows],(i,s,u)=>!s.rows.length||i!==!0&&!Object.keys(i??{}).length||!u?s:Fw(s),fe(l.options,"debugTable"))}function Fw(l){const i=[],s=u=>{var c;i.push(u),(c=u.subRows)!=null&&c.length&&u.getIsExpanded()&&u.subRows.forEach(s)};return l.rows.forEach(s),{rows:i,flatRows:l.flatRows,rowsById:l.rowsById}}function $w(){return l=>ce(()=>[l.getState().sorting,l.getPreSortedRowModel()],(i,s)=>{if(!s.rows.length||!(i!=null&&i.length))return s;const u=l.getState().sorting,c=[],f=u.filter(y=>{var x;return(x=l.getColumn(y.id))==null?void 0:x.getCanSort()}),g={};f.forEach(y=>{const x=l.getColumn(y.id);x&&(g[y.id]={sortUndefined:x.columnDef.sortUndefined,invertSorting:x.columnDef.invertSorting,sortingFn:x.getSortingFn()})});const m=y=>{const x=y.map(v=>({...v}));return x.sort((v,S)=>{for(let N=0;N<f.length;N+=1){var b;const E=f[N],D=g[E.id],_=D.sortUndefined,C=(b=E==null?void 0:E.desc)!=null?b:!1;let U=0;if(_){const B=v.getValue(E.id),$=S.getValue(E.id),F=B===void 0,P=$===void 0;if(F||P){if(_==="first")return F?-1:1;if(_==="last")return F?1:-1;U=F&&P?0:F?_:-_}}if(U===0&&(U=D.sortingFn(v,S,E.id)),U!==0)return C&&(U*=-1),D.invertSorting&&(U*=-1),U}return v.index-S.index}),x.forEach(v=>{var S;c.push(v),(S=v.subRows)!=null&&S.length&&(v.subRows=m(v.subRows))}),x};return{rows:m(s.rows),flatRows:c,rowsById:s.rowsById}},fe(l.options,"debugTable","getSortedRowModel",()=>l._autoResetPageIndex()))}/**
|
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265
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+
color: hsl(${Math.max(0,Math.min(120-120*C,120))}deg 100% 31%);`,s==null?void 0:s.key)}return c}}function fe(l,i,s,u){return{debug:()=>{var c;return(c=l==null?void 0:l.debugAll)!=null?c:l[i]},key:!1,onChange:u}}function iw(l,i,s,u){const c=()=>{var g;return(g=f.getValue())!=null?g:l.options.renderFallbackValue},f={id:`${i.id}_${s.id}`,row:i,column:s,getValue:()=>i.getValue(u),renderValue:c,getContext:ce(()=>[l,s,i,f],(g,m,v,S)=>({table:g,column:m,row:v,cell:S,getValue:S.getValue,renderValue:S.renderValue}),fe(l.options,"debugCells"))};return l._features.forEach(g=>{g.createCell==null||g.createCell(f,s,i,l)},{}),f}function sw(l,i,s,u){var c,f;const m={...l._getDefaultColumnDef(),...i},v=m.accessorKey;let S=(c=(f=m.id)!=null?f:v?typeof String.prototype.replaceAll=="function"?v.replaceAll(".","_"):v.replace(/\./g,"_"):void 0)!=null?c:typeof m.header=="string"?m.header:void 0,y;if(m.accessorFn?y=m.accessorFn:v&&(v.includes(".")?y=C=>{let R=C;for(const O of v.split(".")){var 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l._features.forEach(g=>{g.createHeader==null||g.createHeader(f,l)}),f}const uw={createTable:l=>{l.getHeaderGroups=ce(()=>[l.getAllColumns(),l.getVisibleLeafColumns(),l.getState().columnPinning.left,l.getState().columnPinning.right],(i,s,u,c)=>{var f,g;const m=(f=u==null?void 0:u.map(x=>s.find(C=>C.id===x)).filter(Boolean))!=null?f:[],v=(g=c==null?void 0:c.map(x=>s.find(C=>C.id===x)).filter(Boolean))!=null?g:[],S=s.filter(x=>!(u!=null&&u.includes(x.id))&&!(c!=null&&c.includes(x.id)));return Xo(i,[...m,...S,...v],l)},fe(l.options,Nt)),l.getCenterHeaderGroups=ce(()=>[l.getAllColumns(),l.getVisibleLeafColumns(),l.getState().columnPinning.left,l.getState().columnPinning.right],(i,s,u,c)=>(s=s.filter(f=>!(u!=null&&u.includes(f.id))&&!(c!=null&&c.includes(f.id))),Xo(i,s,l,"center")),fe(l.options,Nt)),l.getLeftHeaderGroups=ce(()=>[l.getAllColumns(),l.getVisibleLeafColumns(),l.getState().columnPinning.left],(i,s,u)=>{var c;const f=(c=u==null?void 0:u.map(g=>s.find(m=>m.id===g)).filter(Boolean))!=null?c:[];return Xo(i,f,l,"left")},fe(l.options,Nt)),l.getRightHeaderGroups=ce(()=>[l.getAllColumns(),l.getVisibleLeafColumns(),l.getState().columnPinning.right],(i,s,u)=>{var c;const f=(c=u==null?void 0:u.map(g=>s.find(m=>m.id===g)).filter(Boolean))!=null?c:[];return Xo(i,f,l,"right")},fe(l.options,Nt)),l.getFooterGroups=ce(()=>[l.getHeaderGroups()],i=>[...i].reverse(),fe(l.options,Nt)),l.getLeftFooterGroups=ce(()=>[l.getLeftHeaderGroups()],i=>[...i].reverse(),fe(l.options,Nt)),l.getCenterFooterGroups=ce(()=>[l.getCenterHeaderGroups()],i=>[...i].reverse(),fe(l.options,Nt)),l.getRightFooterGroups=ce(()=>[l.getRightHeaderGroups()],i=>[...i].reverse(),fe(l.options,Nt)),l.getFlatHeaders=ce(()=>[l.getHeaderGroups()],i=>i.map(s=>s.headers).flat(),fe(l.options,Nt)),l.getLeftFlatHeaders=ce(()=>[l.getLeftHeaderGroups()],i=>i.map(s=>s.headers).flat(),fe(l.options,Nt)),l.getCenterFlatHeaders=ce(()=>[l.getCenterHeaderGroups()],i=>i.map(s=>s.headers).flat(),fe(l.options,Nt)),l.getRightFlatHeaders=ce(()=>[l.getRightHeaderGroups()],i=>i.map(s=>s.headers).flat(),fe(l.options,Nt)),l.getCenterLeafHeaders=ce(()=>[l.getCenterFlatHeaders()],i=>i.filter(s=>{var u;return!((u=s.subHeaders)!=null&&u.length)}),fe(l.options,Nt)),l.getLeftLeafHeaders=ce(()=>[l.getLeftFlatHeaders()],i=>i.filter(s=>{var u;return!((u=s.subHeaders)!=null&&u.length)}),fe(l.options,Nt)),l.getRightLeafHeaders=ce(()=>[l.getRightFlatHeaders()],i=>i.filter(s=>{var u;return!((u=s.subHeaders)!=null&&u.length)}),fe(l.options,Nt)),l.getLeafHeaders=ce(()=>[l.getLeftHeaderGroups(),l.getCenterHeaderGroups(),l.getRightHeaderGroups()],(i,s,u)=>{var c,f,g,m,v,S;return[...(c=(f=i[0])==null?void 0:f.headers)!=null?c:[],...(g=(m=s[0])==null?void 0:m.headers)!=null?g:[],...(v=(S=u[0])==null?void 0:S.headers)!=null?v:[]].map(y=>y.getLeafHeaders()).flat()},fe(l.options,Nt))}};function Xo(l,i,s,u){var c,f;let g=0;const m=function(C,R){R===void 0&&(R=1),g=Math.max(g,R),C.filter(_=>_.getIsVisible()).forEach(_=>{var O;(O=_.columns)!=null&&O.length&&m(_.columns,R+1)},0)};m(l);let v=[];const S=(C,R)=>{const _={depth:R,id:[u,`${R}`].filter(Boolean).join("_"),headers:[]},O=[];C.forEach(b=>{const E=[...O].reverse()[0],U=b.column.depth===_.depth;let B,$=!1;if(U&&b.column.parent?B=b.column.parent:(B=b.column,$=!0),E&&(E==null?void 0:E.column)===B)E.subHeaders.push(b);else{const F=vy(s,B,{id:[u,R,B.id,b==null?void 0:b.id].filter(Boolean).join("_"),isPlaceholder:$,placeholderId:$?`${O.filter(P=>P.column===B).length}`:void 0,depth:R,index:O.length});F.subHeaders.push(b),O.push(F)}_.headers.push(b),b.headerGroup=_}),v.push(_),R>0&&S(O,R-1)},y=i.map((C,R)=>vy(s,C,{depth:g,index:R}));S(y,g-1),v.reverse();const x=C=>C.filter(_=>_.column.getIsVisible()).map(_=>{let O=0,b=0,E=[0];_.subHeaders&&_.subHeaders.length?(E=[],x(_.subHeaders).forEach(B=>{let{colSpan:$,rowSpan:F}=B;O+=$,E.push(F)})):O=1;const U=Math.min(...E);return b=b+U,_.colSpan=O,_.rowSpan=b,{colSpan:O,rowSpan:b}});return x((c=(f=v[0])==null?void 0:f.headers)!=null?c:[]),v}const ow=(l,i,s,u,c,f,g)=>{let m={id:i,index:u,original:s,depth:c,parentId:g,_valuesCache:{},_uniqueValuesCache:{},getValue:v=>{if(m._valuesCache.hasOwnProperty(v))return m._valuesCache[v];const S=l.getColumn(v);if(S!=null&&S.accessorFn)return m._valuesCache[v]=S.accessorFn(m.original,u),m._valuesCache[v]},getUniqueValues:v=>{if(m._uniqueValuesCache.hasOwnProperty(v))return m._uniqueValuesCache[v];const S=l.getColumn(v);if(S!=null&&S.accessorFn)return S.columnDef.getUniqueValues?(m._uniqueValuesCache[v]=S.columnDef.getUniqueValues(m.original,u),m._uniqueValuesCache[v]):(m._uniqueValuesCache[v]=[m.getValue(v)],m._uniqueValuesCache[v])},renderValue:v=>{var S;return(S=m.getValue(v))!=null?S:l.options.renderFallbackValue},subRows:[],getLeafRows:()=>aw(m.subRows,v=>v.subRows),getParentRow:()=>m.parentId?l.getRow(m.parentId,!0):void 0,getParentRows:()=>{let v=[],S=m;for(;;){const y=S.getParentRow();if(!y)break;v.push(y),S=y}return 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Ws={alphanumeric:Dw,alphanumericCaseSensitive:Uw,text:Hw,textCaseSensitive:Lw,datetime:Vw,basic:Bw},Gw={getInitialState:l=>({sorting:[],...l}),getDefaultColumnDef:()=>({sortingFn:"auto",sortUndefined:1}),getDefaultOptions:l=>({onSortingChange:ln("sorting",l),isMultiSortEvent:i=>i.shiftKey}),createColumn:(l,i)=>{l.getAutoSortingFn=()=>{const s=i.getFilteredRowModel().flatRows.slice(10);let u=!1;for(const c of s){const f=c==null?void 0:c.getValue(l.id);if(Object.prototype.toString.call(f)==="[object Date]")return Ws.datetime;if(typeof f=="string"&&(u=!0,f.split(Fd).length>1))return Ws.alphanumeric}return u?Ws.text:Ws.basic},l.getAutoSortDir=()=>{const s=i.getFilteredRowModel().flatRows[0];return typeof(s==null?void 0:s.getValue(l.id))=="string"?"asc":"desc"},l.getSortingFn=()=>{var s,u;if(!l)throw new Error;return gr(l.columnDef.sortingFn)?l.columnDef.sortingFn:l.columnDef.sortingFn==="auto"?l.getAutoSortingFn():(s=(u=i.options.sortingFns)==null?void 0:u[l.columnDef.sortingFn])!=null?s:Ws[l.columnDef.sortingFn]},l.toggleSorting=(s,u)=>{const c=l.getNextSortingOrder(),f=typeof s<"u"&&s!==null;i.setSorting(g=>{const m=g==null?void 0:g.find(R=>R.id===l.id),v=g==null?void 0:g.findIndex(R=>R.id===l.id);let S=[],y,x=f?s:c==="desc";if(g!=null&&g.length&&l.getCanMultiSort()&&u?m?y="toggle":y="add":g!=null&&g.length&&v!==g.length-1?y="replace":m?y="toggle":y="replace",y==="toggle"&&(f||c||(y="remove")),y==="add"){var C;S=[...g,{id:l.id,desc:x}],S.splice(0,S.length-((C=i.options.maxMultiSortColCount)!=null?C:Number.MAX_SAFE_INTEGER))}else y==="toggle"?S=g.map(R=>R.id===l.id?{...R,desc:x}:R):y==="remove"?S=g.filter(R=>R.id!==l.id):S=[{id:l.id,desc:x}];return S})},l.getFirstSortDir=()=>{var s,u;return((s=(u=l.columnDef.sortDescFirst)!=null?u:i.options.sortDescFirst)!=null?s:l.getAutoSortDir()==="desc")?"desc":"asc"},l.getNextSortingOrder=s=>{var u,c;const f=l.getFirstSortDir(),g=l.getIsSorted();return g?g!==f&&((u=i.options.enableSortingRemoval)==null||u)&&(!(s&&(c=i.options.enableMultiRemove)!=null)||c)?!1:g==="desc"?"asc":"desc":f},l.getCanSort=()=>{var s,u;return((s=l.columnDef.enableSorting)!=null?s:!0)&&((u=i.options.enableSorting)!=null?u:!0)&&!!l.accessorFn},l.getCanMultiSort=()=>{var s,u;return(s=(u=l.columnDef.enableMultiSort)!=null?u:i.options.enableMultiSort)!=null?s:!!l.accessorFn},l.getIsSorted=()=>{var s;const u=(s=i.getState().sorting)==null?void 0:s.find(c=>c.id===l.id);return u?u.desc?"desc":"asc":!1},l.getSortIndex=()=>{var s,u;return(s=(u=i.getState().sorting)==null?void 0:u.findIndex(c=>c.id===l.id))!=null?s:-1},l.clearSorting=()=>{i.setSorting(s=>s!=null&&s.length?s.filter(u=>u.id!==l.id):[])},l.getToggleSortingHandler=()=>{const s=l.getCanSort();return u=>{s&&(u.persist==null||u.persist(),l.toggleSorting==null||l.toggleSorting(void 0,l.getCanMultiSort()?i.options.isMultiSortEvent==null?void 0:i.options.isMultiSortEvent(u):!1))}}},createTable:l=>{l.setSorting=i=>l.options.onSortingChange==null?void 0:l.options.onSortingChange(i),l.resetSorting=i=>{var s,u;l.setSorting(i?[]:(s=(u=l.initialState)==null?void 0:u.sorting)!=null?s:[])},l.getPreSortedRowModel=()=>l.getGroupedRowModel(),l.getSortedRowModel=()=>(!l._getSortedRowModel&&l.options.getSortedRowModel&&(l._getSortedRowModel=l.options.getSortedRowModel(l)),l.options.manualSorting||!l._getSortedRowModel?l.getPreSortedRowModel():l._getSortedRowModel())}},qw=[uw,Nw,Cw,Ew,rw,cw,Tw,Mw,Gw,xw,jw,Aw,Ow,zw,Rw];function Fw(l){var i,s;const u=[...qw,...(i=l._features)!=null?i:[]];let c={_features:u};const f=c._features.reduce((C,R)=>Object.assign(C,R.getDefaultOptions==null?void 0:R.getDefaultOptions(c)),{}),g=C=>c.options.mergeOptions?c.options.mergeOptions(f,C):{...f,...C};let v={...{},...(s=l.initialState)!=null?s:{}};c._features.forEach(C=>{var R;v=(R=C.getInitialState==null?void 0:C.getInitialState(v))!=null?R:v});const S=[];let y=!1;const x={_features:u,options:{...f,...l},initialState:v,_queue:C=>{S.push(C),y||(y=!0,Promise.resolve().then(()=>{for(;S.length;)S.shift()();y=!1}).catch(R=>setTimeout(()=>{throw R})))},reset:()=>{c.setState(c.initialState)},setOptions:C=>{const R=Kl(C,c.options);c.options=g(R)},getState:()=>c.options.state,setState:C=>{c.options.onStateChange==null||c.options.onStateChange(C)},_getRowId:(C,R,_)=>{var O;return(O=c.options.getRowId==null?void 0:c.options.getRowId(C,R,_))!=null?O:`${_?[_.id,R].join("."):R}`},getCoreRowModel:()=>(c._getCoreRowModel||(c._getCoreRowModel=c.options.getCoreRowModel(c)),c._getCoreRowModel()),getRowModel:()=>c.getPaginationRowModel(),getRow:(C,R)=>{let _=(R?c.getPrePaginationRowModel():c.getRowModel()).rowsById[C];if(!_&&(_=c.getCoreRowModel().rowsById[C],!_))throw new Error;return _},_getDefaultColumnDef:ce(()=>[c.options.defaultColumn],C=>{var R;return C=(R=C)!=null?R:{},{header:_=>{const O=_.header.column.columnDef;return O.accessorKey?O.accessorKey:O.accessorFn?O.id:null},cell:_=>{var O,b;return(O=(b=_.renderValue())==null||b.toString==null?void 0:b.toString())!=null?O:null},...c._features.reduce((_,O)=>Object.assign(_,O.getDefaultColumnDef==null?void 0:O.getDefaultColumnDef()),{}),...C}},fe(l,"debugColumns")),_getColumnDefs:()=>c.options.columns,getAllColumns:ce(()=>[c._getColumnDefs()],C=>{const R=function(_,O,b){return b===void 0&&(b=0),_.map(E=>{const U=sw(c,E,b,O),B=E;return U.columns=B.columns?R(B.columns,U,b+1):[],U})};return R(C)},fe(l,"debugColumns")),getAllFlatColumns:ce(()=>[c.getAllColumns()],C=>C.flatMap(R=>R.getFlatColumns()),fe(l,"debugColumns")),_getAllFlatColumnsById:ce(()=>[c.getAllFlatColumns()],C=>C.reduce((R,_)=>(R[_.id]=_,R),{}),fe(l,"debugColumns")),getAllLeafColumns:ce(()=>[c.getAllColumns(),c._getOrderColumnsFn()],(C,R)=>{let _=C.flatMap(O=>O.getLeafColumns());return R(_)},fe(l,"debugColumns")),getColumn:C=>c._getAllFlatColumnsById()[C]};Object.assign(c,x);for(let C=0;C<c._features.length;C++){const R=c._features[C];R==null||R.createTable==null||R.createTable(c)}return c}function Z0(){return l=>ce(()=>[l.options.data],i=>{const s={rows:[],flatRows:[],rowsById:{}},u=function(c,f,g){f===void 0&&(f=0);const m=[];for(let S=0;S<c.length;S++){const y=ow(l,l._getRowId(c[S],S,g),c[S],S,f,void 0,g==null?void 0:g.id);if(s.flatRows.push(y),s.rowsById[y.id]=y,m.push(y),l.options.getSubRows){var v;y.originalSubRows=l.options.getSubRows(c[S],S),(v=y.originalSubRows)!=null&&v.length&&(y.subRows=u(y.originalSubRows,f+1,y))}}return m};return s.rows=u(i),s},fe(l.options,"debugTable","getRowModel",()=>l._autoResetPageIndex()))}function K0(){return l=>ce(()=>[l.getState().expanded,l.getPreExpandedRowModel(),l.options.paginateExpandedRows],(i,s,u)=>!s.rows.length||i!==!0&&!Object.keys(i??{}).length||!u?s:I0(s),fe(l.options,"debugTable"))}function I0(l){const i=[],s=u=>{var c;i.push(u),(c=u.subRows)!=null&&c.length&&u.getIsExpanded()&&u.subRows.forEach(s)};return l.rows.forEach(s),{rows:i,flatRows:l.flatRows,rowsById:l.rowsById}}function $w(l){return i=>ce(()=>[i.getState().pagination,i.getPrePaginationRowModel(),i.options.paginateExpandedRows?void 0:i.getState().expanded],(s,u)=>{if(!u.rows.length)return u;const{pageSize:c,pageIndex:f}=s;let{rows:g,flatRows:m,rowsById:v}=u;const S=c*f,y=S+c;g=g.slice(S,y);let x;i.options.paginateExpandedRows?x={rows:g,flatRows:m,rowsById:v}:x=I0({rows:g,flatRows:m,rowsById:v}),x.flatRows=[];const C=R=>{x.flatRows.push(R),R.subRows.length&&R.subRows.forEach(C)};return x.rows.forEach(C),x},fe(i.options,"debugTable"))}function kw(){return l=>ce(()=>[l.getState().sorting,l.getPreSortedRowModel()],(i,s)=>{if(!s.rows.length||!(i!=null&&i.length))return s;const u=l.getState().sorting,c=[],f=u.filter(v=>{var S;return(S=l.getColumn(v.id))==null?void 0:S.getCanSort()}),g={};f.forEach(v=>{const S=l.getColumn(v.id);S&&(g[v.id]={sortUndefined:S.columnDef.sortUndefined,invertSorting:S.columnDef.invertSorting,sortingFn:S.getSortingFn()})});const m=v=>{const S=v.map(y=>({...y}));return S.sort((y,x)=>{for(let R=0;R<f.length;R+=1){var C;const _=f[R],O=g[_.id],b=O.sortUndefined,E=(C=_==null?void 0:_.desc)!=null?C:!1;let U=0;if(b){const B=y.getValue(_.id),$=x.getValue(_.id),F=B===void 0,P=$===void 0;if(F||P){if(b==="first")return F?-1:1;if(b==="last")return F?1:-1;U=F&&P?0:F?b:-b}}if(U===0&&(U=O.sortingFn(y,x,_.id)),U!==0)return E&&(U*=-1),O.invertSorting&&(U*=-1),U}return y.index-x.index}),S.forEach(y=>{var x;c.push(y),(x=y.subRows)!=null&&x.length&&(y.subRows=m(y.subRows))}),S};return{rows:m(s.rows),flatRows:c,rowsById:s.rowsById}},fe(l.options,"debugTable","getSortedRowModel",()=>l._autoResetPageIndex()))}/**
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*/function tr(l,i){return l?kw(l)?j.createElement(l,i):l:null}function kw(l){return Qw(l)||typeof l=="function"||Yw(l)}function Qw(l){return typeof l=="function"&&(()=>{const i=Object.getPrototypeOf(l);return i.prototype&&i.prototype.isReactComponent})()}function Yw(l){return typeof l=="object"&&typeof l.$$typeof=="symbol"&&["react.memo","react.forward_ref"].includes(l.$$typeof.description)}function Z0(l){const i={state:{},onStateChange:()=>{},renderFallbackValue:null,...l},[s]=j.useState(()=>({current:qw(i)})),[u,c]=j.useState(()=>s.current.initialState);return s.current.setOptions(f=>({...f,...l,state:{...u,...l.state},onStateChange:g=>{c(g),l.onStateChange==null||l.onStateChange(g)}})),s.current}function fd({text:l,query:i}){const s=i.trim();if(!s||QC(s))return d.jsx(d.Fragment,{children:l});const u=[],c=l.toLowerCase(),f=s.toLowerCase();let g=0;for(let m=c.indexOf(f);m!==-1;m=c.indexOf(f,g))m>g&&u.push(l.slice(g,m)),u.push(d.jsx("mark",{children:l.slice(m,m+s.length)},m)),g=m+s.length;return u.push(l.slice(g)),d.jsx(d.Fragment,{children:u})}function yy({value:l,max:i,clonal:s}){return l===null?d.jsx("span",{style:{color:"var(--chev)"},children:"–"}):d.jsxs("span",{className:"vbar",children:[d.jsx("span",{className:"vbar-n",children:Ad(l)}),d.jsxs("span",{className:"vbar-track","aria-hidden":!0,children:[d.jsx("span",{className:"vbar-fill",style:{width:`${Math.min(l/i,1)*100}%`}}),s&&d.jsx("span",{className:"vbar-tick",style:{left:`${1/i*100}%`}})]})]})}function Xw({variant:l,showDriver:i}){return d.jsxs("span",{className:"flex flex-wrap gap-1.5",children:[i&&l.is_driver&&d.jsx("span",{className:"sc-pill p-neu",children:"Driver"}),l.hotspot&&d.jsx("span",{className:"sc-pill p-hot",children:"Hotspot"}),l.in_dmp&&d.jsx("span",{className:"sc-pill p-dmp",children:"In DMP"}),l.ffpe_removed&&d.jsx("span",{className:"sc-pill p-ffpe",title:"Left out of the report's counts by its FFPE artifact filter",children:"FFPE filtered"})]})}function Zw(l){return`${l.ref}>${l.alt}`}function Kw({variant:l,onLocate:i}){const[s,u]=j.useState(!1),c=`chr${l.chrom}:${l.pos}`,f=[["Variant",`${l.kind==="snv"?"SNV":l.kind==="indel"?"Indel":l.kind}, ${Zw(l)}`],...l.depth!==null?[["Reads",`${l.alt_reads??"?"} of ${l.depth}`]]:[],["Normal VAF",Ad(l.normal_vaf)],["Mutant copies",KC(l.mut_alleles)??"–"],["Consequence",(l.consequence??l.effect??"–").replace(/&/g,", ")],["COSMIC",ZC(l.cosmic)??"–"],...l.ffpe_score!==null||l.ffpe_removed?[["FFPE artifact score",l.ffpe_score!==null?Ad(l.ffpe_score):"Not scored"]]:[],["Expression",l.gene_tpm!==null?`${l.gene_tpm.toFixed(1)} TPM`:"–"],["Gene role",IC(l)??"–"]];return d.jsxs("div",{className:"vt-detail-body",children:[d.jsx("dl",{className:"vt-facts",children:f.map(([g,m])=>d.jsxs("div",{children:[d.jsx("dt",{children:g}),d.jsx("dd",{children:m})]},g))}),d.jsxs("div",{className:"flex flex-wrap items-center gap-2",children:[d.jsxs("button",{type:"button",className:"sc-btn sc-b2 sm",onClick:()=>i(l),children:[d.jsx(jd,{size:14,"aria-hidden":!0}),"Show on copy number"]}),d.jsxs("button",{type:"button",className:"sc-btn sc-b2 sm",onClick:async()=>{try{await navigator.clipboard.writeText(c),u(!0),window.setTimeout(()=>u(!1),1500)}catch{window.prompt("Copy this locus",c)}},children:[d.jsx(u0,{size:14,"aria-hidden":!0}),s?"Copied":"Copy locus"]})]})]})}function Iw({data:l,pageSize:i,onPage:s,onPageSize:u}){const c=Math.max(1,Math.ceil(l.total/l.page_size)),f=(l.page-1)*l.page_size+1,g=Math.min(l.page*l.page_size,l.total),m=y=>y.toLocaleString("en-US");return d.jsxs("div",{className:"pager",children:[d.jsx("span",{children:l.total===0?"No mutations":`${m(f)}–${m(g)} of ${m(l.total)}`}),d.jsxs("span",{className:"flex items-center gap-4",children:[d.jsxs("label",{className:"flex items-center gap-2",children:["Rows",d.jsx("select",{value:i,onChange:y=>u(Number(y.target.value)),children:qC.map(y=>d.jsx("option",{value:y,children:y},y))})]}),d.jsxs("span",{children:["Page ",m(l.page)," of ",m(c)]}),d.jsxs("span",{className:"flex gap-1",children:[d.jsx("button",{type:"button",className:"sc-ib sm","aria-label":"Previous page",disabled:l.page<=1,onClick:()=>s(l.page-1),children:d.jsx(aC,{size:15,"aria-hidden":!0})}),d.jsx("button",{type:"button",className:"sc-ib sm","aria-label":"Next page",disabled:l.page>=c,onClick:()=>s(l.page+1),children:d.jsx(ir,{size:15,"aria-hidden":!0})})]})]})]})}function Jw({sort:l,current:i,onSort:s}){const u=i.replace(/^-/,"")===l.key,c=i.startsWith("-"),f=u?c?l.key:`-${l.key}`:l.descFirst?`-${l.key}`:l.key;return d.jsxs("button",{type:"button",className:"vt-sort","data-active":u,onClick:()=>s(f),title:`Sort by ${l.label.toLowerCase()}`,children:[l.label,u&&c?d.jsx(Po,{size:12,"aria-hidden":!0}):u?d.jsx(s0,{size:12,"aria-hidden":!0}):d.jsx(Po,{size:12,"aria-hidden":!0,className:"vt-sort-idle"})]})}function Pw({data:l,table:i,fetching:s,showCcf:u,onTable:c,onHover:f,onLocate:g}){const[m,y]=j.useState({}),x=i.q,v=i.scope!=="drivers",S=j.useMemo(()=>[{id:"expand",header:()=>d.jsx("span",{className:"sr-only",children:"Details"}),meta:{className:"pin vt-x"},cell:({row:_})=>d.jsx("button",{type:"button",className:"vt-expand","aria-expanded":_.getIsExpanded(),"aria-label":`Details of ${_.original.gene??"this mutation"} ${_.original.protein_change??""}`.trim(),onClick:C=>{C.stopPropagation(),_.toggleExpanded()},onFocus:()=>f(_.original),children:d.jsx(ir,{size:14,"aria-hidden":!0})})},{id:"gene",header:"Gene",meta:{className:"pin vt-g",sorts:[{key:"gene",label:"Gene"},{key:"position",label:"Position"}]},cell:({row:{original:_}})=>d.jsxs(d.Fragment,{children:[d.jsx("span",{className:"vt-gene",children:d.jsx(fd,{text:_.gene??"–",query:x})}),d.jsx("span",{className:"vt-sub mono",children:su(_.chrom,_.pos)})]})},{id:"change",header:"Change",cell:({row:{original:_}})=>d.jsxs(d.Fragment,{children:[d.jsx("span",{className:"mono block text-[12.5px] font-medium",children:d.jsx(fd,{text:_.protein_change??"–",query:x})}),_.cdna_change&&d.jsx("span",{className:"vt-sub mono",children:d.jsx(fd,{text:_.cdna_change,query:x})})]})},{id:"effect",header:"Effect",meta:{sorts:[{key:"effect",label:"Effect"}]},cell:({row:{original:_}})=>d.jsx("span",{className:_.effect_class==="truncating"?"font-semibold":void 0,children:EC(_.consequence,_.effect)})},{id:"vaf",header:"VAF",meta:{className:"n",sorts:[{key:"vaf",label:"VAF",descFirst:!0}]},cell:({row:{original:_}})=>d.jsx(yy,{value:_.vaf,max:1})},...u?[{id:"ccf",header:"CCF",meta:{className:"n",sorts:[{key:"ccf",label:"CCF",descFirst:!0}]},cell:({row:{original:_}})=>d.jsx(yy,{value:_.ccf,max:1.25,clonal:!0})}]:[],{id:"flags",header:"Flags",cell:({row:{original:_}})=>d.jsx(Xw,{variant:_,showDriver:v})}],[x,v,u,f]),b=Z0({data:l.rows,columns:S,getRowId:$C,getCoreRowModel:Y0(),getExpandedRowModel:X0(),getRowCanExpand:()=>!0,manualPagination:!0,state:{expanded:m},onExpandedChange:y}),N=i.sort.replace(/^-/,""),E=b.getVisibleLeafColumns().length,D=S0(i)>0;return d.jsxs("div",{className:"flex min-w-0 flex-col",children:[d.jsxs("div",{className:"vt-scroll",onMouseLeave:()=>f(null),"aria-busy":s,children:[s&&d.jsx("div",{className:"vt-progress","aria-hidden":!0}),d.jsxs("table",{className:"vt",children:[d.jsx("thead",{children:b.getHeaderGroups().map(_=>d.jsx("tr",{children:_.headers.map(C=>{var $;const U=C.column.columnDef.meta,B=($=U==null?void 0:U.sorts)==null?void 0:$.some(F=>F.key===N);return d.jsx("th",{className:U==null?void 0:U.className,"aria-sort":B?i.sort.startsWith("-")?"descending":"ascending":void 0,children:U!=null&&U.sorts?d.jsx("span",{className:"vt-sorts",children:U.sorts.map(F=>d.jsx(Jw,{sort:F,current:i.sort,onSort:P=>c({sort:P})},F.key))}):tr(C.column.columnDef.header,C.getContext())},C.id)})},_.id))}),d.jsxs("tbody",{children:[b.getRowModel().rows.map(_=>d.jsxs(j.Fragment,{children:[d.jsx("tr",{className:"vt-row","data-expanded":_.getIsExpanded(),onClick:()=>_.toggleExpanded(),onMouseEnter:()=>f(_.original),children:_.getVisibleCells().map(C=>{var U;return d.jsx("td",{className:(U=C.column.columnDef.meta)==null?void 0:U.className,children:tr(C.column.columnDef.cell,C.getContext())},C.id)})}),_.getIsExpanded()&&d.jsx("tr",{className:"vt-detail",children:d.jsx("td",{colSpan:E,children:d.jsx(Kw,{variant:_.original,onLocate:g})})})]},_.id)),l.rows.length===0&&d.jsx("tr",{children:d.jsx("td",{colSpan:E,children:d.jsx("div",{className:"vt-empty",children:D?d.jsxs(d.Fragment,{children:["No mutations match these filters.",d.jsx("button",{type:"button",className:"sc-btn sc-b2 sm",onClick:()=>c({q:"",effects:[],flags:[],range:null}),children:"Clear all filters"})]}):`No ${i.scope==="all"?"":`${i.scope} `}mutations in this sample.`})})})]})]})]}),d.jsx(Iw,{data:l,pageSize:i.pageSize,onPage:_=>c({page:_}),onPageSize:_=>c({pageSize:_})})]})}const Ww=j.forwardRef(function({variants:i,variantsLoading:s,variantsFetching:u,density:c,densityLoading:f,picked:g,measure:m,onMeasure:y,table:x,onTable:v,hovered:S,onHover:b,onLocate:N,showCcf:E},D){var P,X;const _=(i==null?void 0:i.status)==="ok"?i.data??void 0:void 0,C=_==null?void 0:_.counts,U=(c==null?void 0:c.status)==="ok"?(P=c.data)==null?void 0:P.total:void 0,B=(c==null?void 0:c.status)==="ok"?(X=c.data)==null?void 0:X.ffpe:null,$=Z=>Z===void 0?"":Z.toLocaleString("en-US"),F=x.range&&x.range.measure===m?[x.range.low,x.range.high]:null;return d.jsxs(eh,{ref:D,title:"Mutations",subtitle:U!==void 0?`${$(U)} PASS SNVs and indels${B&&!B.shown?", after the FFPE filter":""}`:void 0,lineage:N0(c==null?void 0:c.lineage,i==null?void 0:i.lineage),picked:g,className:"mut",info:"mutations",controls:d.jsxs(d.Fragment,{children:[d.jsx(tw,{value:x.q,onChange:Z=>v({q:Z})}),d.jsx(hr,{label:"Which mutations",value:x.scope,onChange:Z=>v({scope:Z,sort:y0[Z]}),options:[{value:"drivers",label:d.jsxs(d.Fragment,{children:["Drivers",d.jsx("span",{className:"seg-n",children:$(C==null?void 0:C.drivers)})]})},{value:"coding",label:d.jsxs(d.Fragment,{children:["Coding",d.jsx("span",{className:"seg-n",children:$(C==null?void 0:C.coding)})]})},{value:"all",label:d.jsxs(d.Fragment,{children:["All",d.jsx("span",{className:"seg-n",children:$(C==null?void 0:C.all)})]})}]})]}),children:[d.jsx(JE,{envelope:c,loading:f,measure:m,onMeasure:y,range:F,focus:S,onRange:Z=>{!Z&&!x.range||v({range:Z?{measure:m,low:Z[0],high:Z[1]}:null})},onGene:Z=>v({q:Z})}),_&&i&&i.warnings.length>0&&d.jsx("div",{className:"px-5 py-2 text-xs",role:"note",style:{color:"var(--warn-ink)"},children:i.warnings.join(" ")}),_?d.jsxs("div",{className:"mut-body",children:[d.jsx(ew,{table:x,data:_,onChange:v}),d.jsx(Pw,{data:_,table:x,fetching:u,showCcf:E,onTable:v,onHover:b,onLocate:N})]}):d.jsx("div",{className:"mut-rule",children:d.jsx(dr,{label:"mutations",envelope:i,loading:s,skeletonHeight:240,children:()=>null})})]})}),K0={oncogene:"Oncogene",tsg:"Tumour suppressor",both:"Oncogene and 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0:$a.lineage),un((es=pt.data)==null?void 0:es.lineage),un((Sn=Yt.data)==null?void 0:Sn.lineage);for(const I of Mt)I.state==="failed"&&tt.length>0&&Vt.add(_t(I));return d.jsxs("div",{className:`wgts ${Qn.theme}`,children:[d.jsx(cE,{individualId:l,sampleCount:(ie==null?void 0:ie.samples.length)??0,mode:ie==null?void 0:ie.mode,fingerprint:T,analyses:Mt,onPage:Vt,sampleLabel:sn,picked:c,onPick:f}),d.jsxs("div",{ref:te,className:"page",style:ye?{minHeight:ye.height}:void 0,children:[d.jsx(g0,{individualId:l,subtitle:[E_(ie),(ka=ie==null?void 0:ie.individual.sex)==null?void 0:ka.toLowerCase()].filter(Boolean).join(", ")||void 0,patientIcon:ie?d.jsx(jC,{sex:ie.individual.sex}):void 0,compact:ie&&qe?d.jsx(HC,{data:ie,sampleId:qe,fingerprint:((Qa=Ne.data)==null?void 0:Qa.data)??void 0,onSample:ee}):void 0,showCompact:!U}),d.jsxs("main",{className:"flex flex-col gap-5 px-8 pt-[18px] pb-10",children:[Le.isPending&&d.jsx("div",{className:"skeleton h-24","aria-label":"Loading the patient"}),na&&d.jsx("div",{className:"sc-card px-6 py-5",children:d.jsx(Ma,{envelope:{status:"error",data:null,lineage:[],warnings:[na.message]}})}),Le.isError&&!na&&d.jsx("div",{className:"sc-card px-6 py-5",children:d.jsx(Ma,{envelope:{status:"error",data:null,lineage:[],warnings:[Le.error.message]}})}),ge&&ge.status!=="ok"&&d.jsx("div",{className:"sc-card px-6 py-5",children:d.jsx(Ma,{envelope:ge})}),(ge==null?void 0:ge.status)==="ok"&&ge.warnings.length>0&&d.jsx("div",{className:"sc-card px-6 py-4",children:d.jsx(Ma,{envelope:{...ge,status:"missing"}})}),ie&&qe&&d.jsxs(d.Fragment,{children:[d.jsx("div",{ref:C,children:d.jsx(yE,{data:ie,fingerprint:((mu=Ne.data)==null?void 0:mu.data)??void 0,sampleId:qe,onSample:I=>oe("sample",I),onVersion:I=>oe("version",I)})}),d.jsx(wE,{sampleLabel:sn,failures:tt,analyses:Mt}),Y?d.jsxs(d.Fragment,{children:[d.jsx(EE,{sampleLabel:`${sn} tumour`,fingerprint:T,metrics:ae.data,picked:c,lineage:N0((ts=ae.data)==null?void 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Its germline and quality panels arrive with those sections.`]}})})]})]})]})]})}const __=new Ob({defaultOptions:{queries:{staleTime:6e4,refetchOnWindowFocus:!1}}});function R_(){return d.jsx(sb,{client:__,children:d.jsx($2,{basename:Qn.basePath,children:d.jsxs(U2,{children:[d.jsx(_d,{path:"/",element:d.jsx(oE,{})}),d.jsx(_d,{path:"/:individual",element:d.jsx(w_,{})})]})})})}ib.createRoot(document.getElementById("root")).render(d.jsx(j.StrictMode,{children:d.jsx(R_,{})}));export{d as j,j as r};
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*/function nr(l,i){return l?Qw(l)?j.createElement(l,i):l:null}function Qw(l){return Yw(l)||typeof l=="function"||Xw(l)}function Yw(l){return typeof l=="function"&&(()=>{const i=Object.getPrototypeOf(l);return i.prototype&&i.prototype.isReactComponent})()}function Xw(l){return typeof l=="object"&&typeof l.$$typeof=="symbol"&&["react.memo","react.forward_ref"].includes(l.$$typeof.description)}function J0(l){const i={state:{},onStateChange:()=>{},renderFallbackValue:null,...l},[s]=j.useState(()=>({current:Fw(i)})),[u,c]=j.useState(()=>s.current.initialState);return s.current.setOptions(f=>({...f,...l,state:{...u,...l.state},onStateChange:g=>{c(g),l.onStateChange==null||l.onStateChange(g)}})),s.current}function fd({text:l,query:i}){const s=i.trim();if(!s||YC(s))return d.jsx(d.Fragment,{children:l});const u=[],c=l.toLowerCase(),f=s.toLowerCase();let g=0;for(let 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${Qn.theme}`,children:d.jsx("main",{className:"page",children:d.jsx(_E,{onSignedIn:()=>F.invalidateQueries()})})});const na=an.find(I=>I instanceof v0),sn=Qe&&ie?Wd(Qe.id,ie.individual.id):"",Mt=ie&&qe&&ie.analyses[qe]||[],tt=(ie==null?void 0:ie.failures.filter(I=>I.sample===qe))??[],Fe=new Set(Mt.map(Rt)),Vt=new Set,un=I=>I==null?void 0:I.forEach(ut=>Fe.has(Rt(ut))&&Vt.add(Rt(ut)));for(const I of((Yn=(aa=ae.data)==null?void 0:aa.data)==null?void 0:Yn.metrics)??[])Ud.includes(I.key)&&un(I.sources);un((Fa=Ne.data)==null?void 0:Fa.lineage),un((ia=Ee.data)==null?void 0:ia.lineage),un(($a=mt.data)==null?void 0:$a.lineage),un((es=pt.data)==null?void 0:es.lineage),un((Sn=Yt.data)==null?void 0:Sn.lineage);for(const I of Mt)I.state==="failed"&&tt.length>0&&Vt.add(Rt(I));return d.jsxs("div",{className:`wgts ${Qn.theme}`,children:[d.jsx(fE,{individualId:l,sampleCount:(ie==null?void 0:ie.samples.length)??0,mode:ie==null?void 0:ie.mode,fingerprint:T,analyses:Mt,onPage:Vt,sampleLabel:sn,picked:c,onPick:f}),d.jsxs("div",{ref:te,className:"page",style:ye?{minHeight:ye.height}:void 0,children:[d.jsx(p0,{individualId:l,subtitle:[RR(ie),(ka=ie==null?void 0:ie.individual.sex)==null?void 0:ka.toLowerCase()].filter(Boolean).join(", ")||void 0,patientIcon:ie?d.jsx(OC,{sex:ie.individual.sex}):void 0,compact:ie&&qe?d.jsx(VC,{data:ie,sampleId:qe,fingerprint:((Qa=Ne.data)==null?void 0:Qa.data)??void 0,onSample:ee}):void 0,showCompact:!U}),d.jsxs("main",{className:"flex flex-col gap-5 px-8 pt-[18px] pb-10",children:[Le.isPending&&d.jsx("div",{className:"skeleton h-24","aria-label":"Loading the patient"}),na&&d.jsx("div",{className:"sc-card px-6 py-5",children:d.jsx(Ma,{envelope:{status:"error",data:null,lineage:[],warnings:[na.message]}})}),Le.isError&&!na&&d.jsx("div",{className:"sc-card px-6 py-5",children:d.jsx(Ma,{envelope:{status:"error",data:null,lineage:[],warnings:[Le.error.message]}})}),ge&&ge.status!=="ok"&&d.jsx("div",{className:"sc-card px-6 py-5",children:d.jsx(Ma,{envelope:ge})}),(ge==null?void 0:ge.status)==="ok"&&ge.warnings.length>0&&d.jsx("div",{className:"sc-card px-6 py-4",children:d.jsx(Ma,{envelope:{...ge,status:"missing"}})}),ie&&qe&&d.jsxs(d.Fragment,{children:[d.jsx("div",{ref:E,children:d.jsx(SE,{data:ie,fingerprint:((pu=Ne.data)==null?void 0:pu.data)??void 0,sampleId:qe,onSample:I=>oe("sample",I),onVersion:I=>oe("version",I)})}),d.jsx(RE,{sampleLabel:sn,failures:tt,analyses:Mt}),Y?d.jsxs(d.Fragment,{children:[d.jsx(wE,{sampleLabel:`${sn} tumour`,fingerprint:T,metrics:ae.data,picked:c,lineage:M0((ts=ae.data)==null?void 0:ts.lineage,(Ya=Ne.data)==null?void 0:Ya.lineage)}),d.jsx("div",{ref:O,children:d.jsx(XE,{envelope:Ee.data,loading:Ee.isPending,picked:c,sampleLabel:sn,drivers:k,focus:ne,locate:R,onSegment:X,onGene:Z})}),d.jsx(eR,{ref:$,variants:pt.data,variantsLoading:pt.isPending,variantsFetching:pt.isFetching&&pt.isPlaceholderData,density:mt.data,densityLoading:mt.isPending,picked:c,measure:se,onMeasure:I=>{m(I),v.range&&v.range.measure!==I&&P({range:null})},table:v,onTable:P,hovered:y,onHover:C,onLocate:de,showCcf:ie.mode!=="unmatched"}),d.jsx(bR,{envelope:Yt.data,loading:Yt.isPending,picked:c,onLocate:ve})]}):d.jsx("div",{className:"sc-card px-6 py-5",children:d.jsx(Ma,{envelope:{status:"missing",data:null,lineage:[],warnings:[`${sn} is a normal sample. Its germline and quality panels arrive with those sections.`]}})})]})]})]})]})}const NR=new Ub({defaultOptions:{queries:{staleTime:6e4,refetchOnWindowFocus:!1}}});function TR(){return d.jsx(rb,{client:NR,children:d.jsx(Y2,{basename:Qn.basePath,children:d.jsxs(V2,{children:[d.jsx(Rd,{path:"/",element:d.jsx(rE,{})}),d.jsx(Rd,{path:"/:individual",element:d.jsx(_R,{})})]})})})}ob.createRoot(document.getElementById("root")).render(d.jsx(j.StrictMode,{children:d.jsx(TR,{})}));export{d as j,j as r};
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