saferx-pharma-sdk 1.4.2 → 2.0.1

This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
Files changed (167) hide show
  1. package/dist/cjs/BaseClient.js +2 -2
  2. package/dist/cjs/Client.d.ts +0 -12
  3. package/dist/cjs/Client.js +0 -67
  4. package/dist/cjs/api/resources/developers/client/Client.d.ts +1 -1
  5. package/dist/cjs/api/resources/developers/client/Client.js +1 -1
  6. package/dist/cjs/api/resources/drugSafety/client/Client.d.ts +5 -37
  7. package/dist/cjs/api/resources/drugSafety/client/Client.js +5 -37
  8. package/dist/cjs/api/resources/drugSafety/client/requests/DrugSafetyCheckRequest.d.ts +4 -38
  9. package/dist/cjs/api/resources/drugSafety/types/GetDrugSafetyHealthResponse.d.ts +14 -2
  10. package/dist/cjs/api/resources/drugSafety/types/GetDrugSafetyHealthResponse.js +11 -0
  11. package/dist/cjs/api/types/Alert.d.ts +2 -8
  12. package/dist/cjs/api/types/Alert.js +1 -5
  13. package/dist/cjs/api/types/ClinicalAlert.d.ts +0 -8
  14. package/dist/cjs/api/types/ClinicalData.d.ts +4 -7
  15. package/dist/cjs/api/types/DailyLimit.d.ts +1 -1
  16. package/dist/cjs/api/types/DomainCode.d.ts +2 -4
  17. package/dist/cjs/api/types/DomainCode.js +2 -4
  18. package/dist/cjs/api/types/DosingData.d.ts +12 -22
  19. package/dist/cjs/api/types/DosingData.js +3 -3
  20. package/dist/cjs/api/types/DrugSafetyCheckResponse.d.ts +0 -1
  21. package/dist/cjs/api/types/ErrorResponse.d.ts +0 -5
  22. package/dist/cjs/api/types/Interaction.d.ts +2 -0
  23. package/dist/cjs/api/types/InteractionSummary.d.ts +4 -4
  24. package/dist/cjs/api/types/Meta.d.ts +0 -2
  25. package/dist/cjs/api/types/Meta.js +0 -1
  26. package/dist/cjs/api/types/MetadataResponse.d.ts +6 -14
  27. package/dist/cjs/api/types/MetadataResponse.js +0 -1
  28. package/dist/cjs/api/types/PatientProfile.d.ts +0 -31
  29. package/dist/cjs/api/types/PatientProfile.js +0 -17
  30. package/dist/cjs/api/types/RateLimitResponse.d.ts +0 -11
  31. package/dist/cjs/api/types/RateLimitResponse.js +0 -1
  32. package/dist/cjs/api/types/ReproductiveSafetyData.d.ts +3 -3
  33. package/dist/cjs/api/types/ResolvedDrug.d.ts +0 -26
  34. package/dist/cjs/api/types/SafetyData.d.ts +0 -1
  35. package/dist/cjs/api/types/index.d.ts +0 -16
  36. package/dist/cjs/api/types/index.js +0 -16
  37. package/dist/cjs/core/fetcher/BinaryResponse.d.ts +1 -1
  38. package/dist/cjs/core/fetcher/Fetcher.js +1 -1
  39. package/dist/cjs/core/fetcher/index.d.ts +0 -2
  40. package/dist/cjs/core/fetcher/index.js +1 -3
  41. package/dist/cjs/core/fetcher/makeRequest.d.ts +1 -6
  42. package/dist/cjs/core/fetcher/makeRequest.js +9 -30
  43. package/dist/cjs/core/runtime/runtime.js +7 -8
  44. package/dist/cjs/version.d.ts +1 -1
  45. package/dist/cjs/version.js +1 -1
  46. package/dist/esm/BaseClient.mjs +2 -2
  47. package/dist/esm/Client.d.mts +0 -12
  48. package/dist/esm/Client.mjs +0 -34
  49. package/dist/esm/api/resources/developers/client/Client.d.mts +1 -1
  50. package/dist/esm/api/resources/developers/client/Client.mjs +1 -1
  51. package/dist/esm/api/resources/drugSafety/client/Client.d.mts +5 -37
  52. package/dist/esm/api/resources/drugSafety/client/Client.mjs +5 -37
  53. package/dist/esm/api/resources/drugSafety/client/requests/DrugSafetyCheckRequest.d.mts +4 -38
  54. package/dist/esm/api/resources/drugSafety/types/GetDrugSafetyHealthResponse.d.mts +14 -2
  55. package/dist/esm/api/resources/drugSafety/types/GetDrugSafetyHealthResponse.mjs +11 -0
  56. package/dist/esm/api/types/Alert.d.mts +2 -8
  57. package/dist/esm/api/types/Alert.mjs +1 -5
  58. package/dist/esm/api/types/ClinicalAlert.d.mts +0 -8
  59. package/dist/esm/api/types/ClinicalData.d.mts +4 -7
  60. package/dist/esm/api/types/DailyLimit.d.mts +1 -1
  61. package/dist/esm/api/types/DomainCode.d.mts +2 -4
  62. package/dist/esm/api/types/DomainCode.mjs +2 -4
  63. package/dist/esm/api/types/DosingData.d.mts +12 -22
  64. package/dist/esm/api/types/DosingData.mjs +3 -3
  65. package/dist/esm/api/types/DrugSafetyCheckResponse.d.mts +0 -1
  66. package/dist/esm/api/types/ErrorResponse.d.mts +0 -5
  67. package/dist/esm/api/types/Interaction.d.mts +2 -0
  68. package/dist/esm/api/types/InteractionSummary.d.mts +4 -4
  69. package/dist/esm/api/types/Meta.d.mts +0 -2
  70. package/dist/esm/api/types/Meta.mjs +0 -1
  71. package/dist/esm/api/types/MetadataResponse.d.mts +6 -14
  72. package/dist/esm/api/types/MetadataResponse.mjs +0 -1
  73. package/dist/esm/api/types/PatientProfile.d.mts +0 -31
  74. package/dist/esm/api/types/PatientProfile.mjs +1 -16
  75. package/dist/esm/api/types/RateLimitResponse.d.mts +0 -11
  76. package/dist/esm/api/types/RateLimitResponse.mjs +0 -1
  77. package/dist/esm/api/types/ReproductiveSafetyData.d.mts +3 -3
  78. package/dist/esm/api/types/ResolvedDrug.d.mts +0 -26
  79. package/dist/esm/api/types/SafetyData.d.mts +0 -1
  80. package/dist/esm/api/types/index.d.mts +0 -16
  81. package/dist/esm/api/types/index.mjs +0 -16
  82. package/dist/esm/core/fetcher/BinaryResponse.d.mts +1 -1
  83. package/dist/esm/core/fetcher/Fetcher.mjs +1 -1
  84. package/dist/esm/core/fetcher/index.d.mts +0 -2
  85. package/dist/esm/core/fetcher/index.mjs +0 -1
  86. package/dist/esm/core/fetcher/makeRequest.d.mts +1 -6
  87. package/dist/esm/core/fetcher/makeRequest.mjs +9 -28
  88. package/dist/esm/core/runtime/runtime.mjs +7 -8
  89. package/dist/esm/version.d.mts +1 -1
  90. package/dist/esm/version.mjs +1 -1
  91. package/package.json +9 -31
  92. package/dist/cjs/api/resources/developers/exports.d.ts +0 -2
  93. package/dist/cjs/api/resources/developers/exports.js +0 -21
  94. package/dist/cjs/api/resources/drugSafety/exports.d.ts +0 -2
  95. package/dist/cjs/api/resources/drugSafety/exports.js +0 -21
  96. package/dist/cjs/api/types/AllergyCrossReactivityReference.d.ts +0 -16
  97. package/dist/cjs/api/types/AllergyCrossReactivityReference.js +0 -3
  98. package/dist/cjs/api/types/AllergyData.d.ts +0 -24
  99. package/dist/cjs/api/types/AllergyData.js +0 -11
  100. package/dist/cjs/api/types/AllergyFamilyReference.d.ts +0 -10
  101. package/dist/cjs/api/types/AllergyFamilyReference.js +0 -3
  102. package/dist/cjs/api/types/AllergyInputEntry.d.ts +0 -10
  103. package/dist/cjs/api/types/AllergyInputEntry.js +0 -3
  104. package/dist/cjs/api/types/AllergyProductFamilyReference.d.ts +0 -9
  105. package/dist/cjs/api/types/AllergyProductFamilyReference.js +0 -3
  106. package/dist/cjs/api/types/AllergySummary.d.ts +0 -14
  107. package/dist/cjs/api/types/AllergySummary.js +0 -3
  108. package/dist/cjs/api/types/AllergyWarning.d.ts +0 -30
  109. package/dist/cjs/api/types/AllergyWarning.js +0 -11
  110. package/dist/cjs/api/types/ClinicalContextApplied.d.ts +0 -10
  111. package/dist/cjs/api/types/ClinicalContextApplied.js +0 -3
  112. package/dist/cjs/api/types/IdentityMatch.d.ts +0 -13
  113. package/dist/cjs/api/types/IdentityMatch.js +0 -3
  114. package/dist/cjs/api/types/IntelligenceClinicalProfile.d.ts +0 -24
  115. package/dist/cjs/api/types/IntelligenceClinicalProfile.js +0 -13
  116. package/dist/cjs/api/types/IntelligenceContext.d.ts +0 -17
  117. package/dist/cjs/api/types/IntelligenceContext.js +0 -3
  118. package/dist/cjs/api/types/IntelligenceProcessorError.d.ts +0 -4
  119. package/dist/cjs/api/types/IntelligenceProcessorError.js +0 -3
  120. package/dist/cjs/api/types/IntelligenceResult.d.ts +0 -16
  121. package/dist/cjs/api/types/IntelligenceResult.js +0 -3
  122. package/dist/cjs/api/types/IntelligenceSynthesis.d.ts +0 -6
  123. package/dist/cjs/api/types/IntelligenceSynthesis.js +0 -3
  124. package/dist/cjs/api/types/MedicationHistoryItem.d.ts +0 -22
  125. package/dist/cjs/api/types/MedicationHistoryItem.js +0 -15
  126. package/dist/cjs/api/types/QuotaMeta.d.ts +0 -11
  127. package/dist/cjs/api/types/QuotaMeta.js +0 -3
  128. package/dist/cjs/core/fetcher/makePassthroughRequest.d.ts +0 -49
  129. package/dist/cjs/core/fetcher/makePassthroughRequest.js +0 -135
  130. package/dist/esm/api/resources/developers/exports.d.mts +0 -2
  131. package/dist/esm/api/resources/developers/exports.mjs +0 -3
  132. package/dist/esm/api/resources/drugSafety/exports.d.mts +0 -2
  133. package/dist/esm/api/resources/drugSafety/exports.mjs +0 -3
  134. package/dist/esm/api/types/AllergyCrossReactivityReference.d.mts +0 -16
  135. package/dist/esm/api/types/AllergyCrossReactivityReference.mjs +0 -2
  136. package/dist/esm/api/types/AllergyData.d.mts +0 -24
  137. package/dist/esm/api/types/AllergyData.mjs +0 -8
  138. package/dist/esm/api/types/AllergyFamilyReference.d.mts +0 -10
  139. package/dist/esm/api/types/AllergyFamilyReference.mjs +0 -2
  140. package/dist/esm/api/types/AllergyInputEntry.d.mts +0 -10
  141. package/dist/esm/api/types/AllergyInputEntry.mjs +0 -2
  142. package/dist/esm/api/types/AllergyProductFamilyReference.d.mts +0 -9
  143. package/dist/esm/api/types/AllergyProductFamilyReference.mjs +0 -2
  144. package/dist/esm/api/types/AllergySummary.d.mts +0 -14
  145. package/dist/esm/api/types/AllergySummary.mjs +0 -2
  146. package/dist/esm/api/types/AllergyWarning.d.mts +0 -30
  147. package/dist/esm/api/types/AllergyWarning.mjs +0 -8
  148. package/dist/esm/api/types/ClinicalContextApplied.d.mts +0 -10
  149. package/dist/esm/api/types/ClinicalContextApplied.mjs +0 -2
  150. package/dist/esm/api/types/IdentityMatch.d.mts +0 -13
  151. package/dist/esm/api/types/IdentityMatch.mjs +0 -2
  152. package/dist/esm/api/types/IntelligenceClinicalProfile.d.mts +0 -24
  153. package/dist/esm/api/types/IntelligenceClinicalProfile.mjs +0 -10
  154. package/dist/esm/api/types/IntelligenceContext.d.mts +0 -17
  155. package/dist/esm/api/types/IntelligenceContext.mjs +0 -2
  156. package/dist/esm/api/types/IntelligenceProcessorError.d.mts +0 -4
  157. package/dist/esm/api/types/IntelligenceProcessorError.mjs +0 -2
  158. package/dist/esm/api/types/IntelligenceResult.d.mts +0 -16
  159. package/dist/esm/api/types/IntelligenceResult.mjs +0 -2
  160. package/dist/esm/api/types/IntelligenceSynthesis.d.mts +0 -6
  161. package/dist/esm/api/types/IntelligenceSynthesis.mjs +0 -2
  162. package/dist/esm/api/types/MedicationHistoryItem.d.mts +0 -22
  163. package/dist/esm/api/types/MedicationHistoryItem.mjs +0 -12
  164. package/dist/esm/api/types/QuotaMeta.d.mts +0 -11
  165. package/dist/esm/api/types/QuotaMeta.mjs +0 -2
  166. package/dist/esm/core/fetcher/makePassthroughRequest.d.mts +0 -49
  167. package/dist/esm/core/fetcher/makePassthroughRequest.mjs +0 -132
@@ -43,8 +43,8 @@ function normalizeClientOptions(options) {
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  const headers = (0, headers_js_1.mergeHeaders)({
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  "X-Fern-Language": "JavaScript",
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  "X-Fern-SDK-Name": "saferx-pharma-sdk",
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- "X-Fern-SDK-Version": "1.4.2",
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- "User-Agent": "saferx-pharma-sdk/1.4.2",
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+ "X-Fern-SDK-Version": "2.0.1",
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+ "User-Agent": "saferx-pharma-sdk/2.0.1",
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  "X-Fern-Runtime": core.RUNTIME.type,
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  "X-Fern-Runtime-Version": core.RUNTIME.version,
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  }, options === null || options === void 0 ? void 0 : options.headers);
@@ -2,7 +2,6 @@ import { DevelopersClient } from "./api/resources/developers/client/Client.js";
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  import { DrugSafetyClient } from "./api/resources/drugSafety/client/Client.js";
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  import type { BaseClientOptions, BaseRequestOptions } from "./BaseClient.js";
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  import { type NormalizedClientOptionsWithAuth } from "./BaseClient.js";
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- import * as core from "./core/index.js";
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  export declare namespace SafeRxClient {
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  type Options = BaseClientOptions;
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  interface RequestOptions extends BaseRequestOptions {
@@ -15,15 +14,4 @@ export declare class SafeRxClient {
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  constructor(options?: SafeRxClient.Options);
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  get drugSafety(): DrugSafetyClient;
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  get developers(): DevelopersClient;
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- /**
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- * Make a passthrough request using the SDK's configured auth, retry, logging, etc.
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- * This is useful for making requests to endpoints not yet supported in the SDK.
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- * The input can be a URL string, URL object, or Request object. Relative paths are resolved against the configured base URL.
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- *
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- * @param {Request | string | URL} input - The URL, path, or Request object.
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- * @param {RequestInit} init - Standard fetch RequestInit options.
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- * @param {core.PassthroughRequest.RequestOptions} requestOptions - Per-request overrides (timeout, retries, headers, abort signal).
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- * @returns {Promise<Response>} A standard Response object.
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- */
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- fetch(input: Request | string | URL, init?: RequestInit, requestOptions?: core.PassthroughRequest.RequestOptions): Promise<Response>;
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  }
@@ -1,53 +1,10 @@
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  "use strict";
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  // This file was auto-generated by Fern from our API Definition.
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- var __createBinding = (this && this.__createBinding) || (Object.create ? (function(o, m, k, k2) {
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- if (k2 === undefined) k2 = k;
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- var desc = Object.getOwnPropertyDescriptor(m, k);
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- if (!desc || ("get" in desc ? !m.__esModule : desc.writable || desc.configurable)) {
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- desc = { enumerable: true, get: function() { return m[k]; } };
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- }
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- Object.defineProperty(o, k2, desc);
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- }) : (function(o, m, k, k2) {
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- if (k2 === undefined) k2 = k;
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- o[k2] = m[k];
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- }));
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- var __setModuleDefault = (this && this.__setModuleDefault) || (Object.create ? (function(o, v) {
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- Object.defineProperty(o, "default", { enumerable: true, value: v });
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- }) : function(o, v) {
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- o["default"] = v;
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- });
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- var __importStar = (this && this.__importStar) || (function () {
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- var ownKeys = function(o) {
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- ownKeys = Object.getOwnPropertyNames || function (o) {
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- var ar = [];
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- for (var k in o) if (Object.prototype.hasOwnProperty.call(o, k)) ar[ar.length] = k;
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- return ar;
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- };
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- return ownKeys(o);
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- };
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- return function (mod) {
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- if (mod && mod.__esModule) return mod;
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- var result = {};
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- if (mod != null) for (var k = ownKeys(mod), i = 0; i < k.length; i++) if (k[i] !== "default") __createBinding(result, mod, k[i]);
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- __setModuleDefault(result, mod);
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- return result;
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- };
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- })();
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- var __awaiter = (this && this.__awaiter) || function (thisArg, _arguments, P, generator) {
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- function adopt(value) { return value instanceof P ? value : new P(function (resolve) { resolve(value); }); }
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- return new (P || (P = Promise))(function (resolve, reject) {
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- function fulfilled(value) { try { step(generator.next(value)); } catch (e) { reject(e); } }
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- function rejected(value) { try { step(generator["throw"](value)); } catch (e) { reject(e); } }
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- function step(result) { result.done ? resolve(result.value) : adopt(result.value).then(fulfilled, rejected); }
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- step((generator = generator.apply(thisArg, _arguments || [])).next());
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- });
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- };
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  Object.defineProperty(exports, "__esModule", { value: true });
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  exports.SafeRxClient = void 0;
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  const Client_js_1 = require("./api/resources/developers/client/Client.js");
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  const Client_js_2 = require("./api/resources/drugSafety/client/Client.js");
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  const BaseClient_js_1 = require("./BaseClient.js");
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- const core = __importStar(require("./core/index.js"));
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  class SafeRxClient {
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  constructor(options = {}) {
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  this._options = (0, BaseClient_js_1.normalizeClientOptionsWithAuth)(options);
@@ -60,29 +17,5 @@ class SafeRxClient {
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  var _a;
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  return ((_a = this._developers) !== null && _a !== void 0 ? _a : (this._developers = new Client_js_1.DevelopersClient(this._options)));
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  }
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- /**
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- * Make a passthrough request using the SDK's configured auth, retry, logging, etc.
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- * This is useful for making requests to endpoints not yet supported in the SDK.
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- * The input can be a URL string, URL object, or Request object. Relative paths are resolved against the configured base URL.
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- *
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- * @param {Request | string | URL} input - The URL, path, or Request object.
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- * @param {RequestInit} init - Standard fetch RequestInit options.
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- * @param {core.PassthroughRequest.RequestOptions} requestOptions - Per-request overrides (timeout, retries, headers, abort signal).
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- * @returns {Promise<Response>} A standard Response object.
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- */
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- fetch(input, init, requestOptions) {
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- return __awaiter(this, void 0, void 0, function* () {
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- var _a;
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- return core.makePassthroughRequest(input, init, {
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- baseUrl: (_a = this._options.baseUrl) !== null && _a !== void 0 ? _a : this._options.environment,
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- headers: this._options.headers,
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- timeoutInSeconds: this._options.timeoutInSeconds,
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- maxRetries: this._options.maxRetries,
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- fetch: this._options.fetch,
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- logging: this._options.logging,
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- getAuthHeaders: () => __awaiter(this, void 0, void 0, function* () { return (yield this._options.authProvider.getAuthRequest()).headers; }),
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- }, requestOptions);
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- });
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- }
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  }
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  exports.SafeRxClient = SafeRxClient;
@@ -37,7 +37,7 @@ export declare class DevelopersClient {
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  * - Code expires after 30 minutes
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  * - Max 5 wrong attempts per code (then must request new code)
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  * - On success: issues sfx_free_ key (persistent, 1 per email)
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- * - Free tier: 100 checks/month, 20 requests/minute anti-abuse, 60/day safety cap
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+ * - Free tier: 20 requests/minute, 60 requests/day
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  *
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  * @param {SafeRx.VerifyFreeKeyDevelopersRequest} request
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  * @param {DevelopersClient.RequestOptions} requestOptions - Request-specific configuration.
@@ -124,7 +124,7 @@ class DevelopersClient {
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  * - Code expires after 30 minutes
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  * - Max 5 wrong attempts per code (then must request new code)
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  * - On success: issues sfx_free_ key (persistent, 1 per email)
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- * - Free tier: 100 checks/month, 20 requests/minute anti-abuse, 60/day safety cap
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+ * - Free tier: 20 requests/minute, 60 requests/day
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  *
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  * @param {SafeRx.VerifyFreeKeyDevelopersRequest} request
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  * @param {DevelopersClient.RequestOptions} requestOptions - Request-specific configuration.
@@ -14,7 +14,7 @@ export declare class DrugSafetyClient {
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  protected readonly _options: NormalizedClientOptionsWithAuth<DrugSafetyClient.Options>;
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  constructor(options?: DrugSafetyClient.Options);
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  /**
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- * Screen one or more drugs across seven safety domains in a single request.
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+ * Screen one or more drugs across six safety domains in a single request.
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  *
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  * The API resolves drug names via fuzzy matching, runs all requested safety
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  * checks in parallel, and returns a unified response with alerts bubbled to
@@ -44,40 +44,9 @@ export declare class DrugSafetyClient {
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  * drugs: ["Augmentin 1g", "Glucophage 500mg", "Marivan"],
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  * patient_profile: {
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  * populations: ["geriatric", "renal"],
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- * conditions: ["diabetes", "hypertension"],
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- * allergies: ["penicillin"]
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+ * conditions: ["diabetes", "hypertension"]
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  * },
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- * include: ["ae", "ddi", "pllr", "food", "clinical", "dose", "allergy"],
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- * lang: "en"
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- * })
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- *
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- * @example
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- * await client.drugSafety.check({
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- * drugs: ["Augmentin 1g", "Marivan"],
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- * intelligence_context: {
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- * user_id: "patient-123",
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- * clinical_profile: {
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- * age: 72,
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- * crcl: 38,
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- * hepatic_status: "normal",
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- * pregnancy: false,
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- * lactation: false,
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- * conditions: ["renal impairment", "hypertension"],
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- * populations: ["geriatric", "renal"],
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- * allergies: ["penicillin"],
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- * diet_habits: ["low_sodium"]
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- * },
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- * medication_history: [{
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- * sfrx_id: "SRX-010-004748",
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- * start_date: "2026-01-10",
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- * status: "active"
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- * }, {
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- * sfrx_id: "SRX-050-000123",
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- * start_date: "2025-09-01",
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- * status: "historical"
78
- * }]
79
- * },
80
- * include: ["ae", "ddi", "pllr", "food", "clinical", "dose", "allergy"],
49
+ * include: ["ae", "ddi", "pllr", "clinical"],
81
50
  * lang: "en"
82
51
  * })
83
52
  *
@@ -116,11 +85,10 @@ export declare class DrugSafetyClient {
116
85
  getMetadata(requestOptions?: DrugSafetyClient.RequestOptions): core.HttpResponsePromise<SafeRx.MetadataResponse>;
117
86
  private __getMetadata;
118
87
  /**
119
- * Returns minimal health status of the Drug Safety API subsystem.
88
+ * Returns health status of the Drug Safety API subsystem including
89
+ * overall system health and availability.
120
90
  *
121
91
  * No authentication required. Designed for monitoring services.
122
- * The public enterprise health endpoint intentionally does not expose
123
- * database counts, module internals, or detailed dependency checks.
124
92
  *
125
93
  * @param {DrugSafetyClient.RequestOptions} requestOptions - Request-specific configuration.
126
94
  *
@@ -59,7 +59,7 @@ class DrugSafetyClient {
59
59
  this._options = (0, BaseClient_js_1.normalizeClientOptionsWithAuth)(options);
60
60
  }
61
61
  /**
62
- * Screen one or more drugs across seven safety domains in a single request.
62
+ * Screen one or more drugs across six safety domains in a single request.
63
63
  *
64
64
  * The API resolves drug names via fuzzy matching, runs all requested safety
65
65
  * checks in parallel, and returns a unified response with alerts bubbled to
@@ -89,40 +89,9 @@ class DrugSafetyClient {
89
89
  * drugs: ["Augmentin 1g", "Glucophage 500mg", "Marivan"],
90
90
  * patient_profile: {
91
91
  * populations: ["geriatric", "renal"],
92
- * conditions: ["diabetes", "hypertension"],
93
- * allergies: ["penicillin"]
92
+ * conditions: ["diabetes", "hypertension"]
94
93
  * },
95
- * include: ["ae", "ddi", "pllr", "food", "clinical", "dose", "allergy"],
96
- * lang: "en"
97
- * })
98
- *
99
- * @example
100
- * await client.drugSafety.check({
101
- * drugs: ["Augmentin 1g", "Marivan"],
102
- * intelligence_context: {
103
- * user_id: "patient-123",
104
- * clinical_profile: {
105
- * age: 72,
106
- * crcl: 38,
107
- * hepatic_status: "normal",
108
- * pregnancy: false,
109
- * lactation: false,
110
- * conditions: ["renal impairment", "hypertension"],
111
- * populations: ["geriatric", "renal"],
112
- * allergies: ["penicillin"],
113
- * diet_habits: ["low_sodium"]
114
- * },
115
- * medication_history: [{
116
- * sfrx_id: "SRX-010-004748",
117
- * start_date: "2026-01-10",
118
- * status: "active"
119
- * }, {
120
- * sfrx_id: "SRX-050-000123",
121
- * start_date: "2025-09-01",
122
- * status: "historical"
123
- * }]
124
- * },
125
- * include: ["ae", "ddi", "pllr", "food", "clinical", "dose", "allergy"],
94
+ * include: ["ae", "ddi", "pllr", "clinical"],
126
95
  * lang: "en"
127
96
  * })
128
97
  *
@@ -244,11 +213,10 @@ class DrugSafetyClient {
244
213
  });
245
214
  }
246
215
  /**
247
- * Returns minimal health status of the Drug Safety API subsystem.
216
+ * Returns health status of the Drug Safety API subsystem including
217
+ * overall system health and availability.
248
218
  *
249
219
  * No authentication required. Designed for monitoring services.
250
- * The public enterprise health endpoint intentionally does not expose
251
- * database counts, module internals, or detailed dependency checks.
252
220
  *
253
221
  * @param {DrugSafetyClient.RequestOptions} requestOptions - Request-specific configuration.
254
222
  *
@@ -11,40 +11,9 @@ import type * as SafeRx from "../../../../index.js";
11
11
  * drugs: ["Augmentin 1g", "Glucophage 500mg", "Marivan"],
12
12
  * patient_profile: {
13
13
  * populations: ["geriatric", "renal"],
14
- * conditions: ["diabetes", "hypertension"],
15
- * allergies: ["penicillin"]
14
+ * conditions: ["diabetes", "hypertension"]
16
15
  * },
17
- * include: ["ae", "ddi", "pllr", "food", "clinical", "dose", "allergy"],
18
- * lang: "en"
19
- * }
20
- *
21
- * @example
22
- * {
23
- * drugs: ["Augmentin 1g", "Marivan"],
24
- * intelligence_context: {
25
- * user_id: "patient-123",
26
- * clinical_profile: {
27
- * age: 72,
28
- * crcl: 38,
29
- * hepatic_status: "normal",
30
- * pregnancy: false,
31
- * lactation: false,
32
- * conditions: ["renal impairment", "hypertension"],
33
- * populations: ["geriatric", "renal"],
34
- * allergies: ["penicillin"],
35
- * diet_habits: ["low_sodium"]
36
- * },
37
- * medication_history: [{
38
- * sfrx_id: "SRX-010-004748",
39
- * start_date: "2026-01-10",
40
- * status: "active"
41
- * }, {
42
- * sfrx_id: "SRX-050-000123",
43
- * start_date: "2025-09-01",
44
- * status: "historical"
45
- * }]
46
- * },
47
- * include: ["ae", "ddi", "pllr", "food", "clinical", "dose", "allergy"],
16
+ * include: ["ae", "ddi", "pllr", "clinical"],
48
17
  * lang: "en"
49
18
  * }
50
19
  *
@@ -71,12 +40,9 @@ export interface DrugSafetyCheckRequest {
71
40
  */
72
41
  drugs: string[];
73
42
  patient_profile?: SafeRx.PatientProfile;
74
- intelligence_context?: SafeRx.IntelligenceContext;
75
43
  /**
76
- * Safety domains to check. Omit or pass `null` to run all seven domains.
77
- * When provided, `include` must be a non-empty array of valid lowercase
78
- * domain codes. Unknown domain codes return `400 INVALID_INCLUDE_DOMAIN`.
79
- * Duplicate valid domains are accepted and de-duplicated.
44
+ * Safety domains to check. Omit to run all six domains.
45
+ * Including fewer domains reduces response size and may improve latency.
80
46
  */
81
47
  include?: SafeRx.DomainCode[];
82
48
  /**
@@ -1,8 +1,7 @@
1
1
  export interface GetDrugSafetyHealthResponse {
2
2
  status?: GetDrugSafetyHealthResponse.Status | undefined;
3
3
  subsystem?: string | undefined;
4
- /** Always empty on the public health endpoint. */
5
- checks?: Record<string, unknown> | undefined;
4
+ checks?: Record<string, GetDrugSafetyHealthResponse.Checks.Value> | undefined;
6
5
  latency_ms?: number | undefined;
7
6
  }
8
7
  export declare namespace GetDrugSafetyHealthResponse {
@@ -11,4 +10,17 @@ export declare namespace GetDrugSafetyHealthResponse {
11
10
  readonly Degraded: "degraded";
12
11
  };
13
12
  type Status = (typeof Status)[keyof typeof Status];
13
+ namespace Checks {
14
+ interface Value {
15
+ status?: Value.Status | undefined;
16
+ }
17
+ namespace Value {
18
+ const Status: {
19
+ readonly Healthy: "healthy";
20
+ readonly Degraded: "degraded";
21
+ readonly Unhealthy: "unhealthy";
22
+ };
23
+ type Status = (typeof Status)[keyof typeof Status];
24
+ }
25
+ }
14
26
  }
@@ -8,4 +8,15 @@ var GetDrugSafetyHealthResponse;
8
8
  Healthy: "healthy",
9
9
  Degraded: "degraded",
10
10
  };
11
+ let Checks;
12
+ (function (Checks) {
13
+ let Value;
14
+ (function (Value) {
15
+ Value.Status = {
16
+ Healthy: "healthy",
17
+ Degraded: "degraded",
18
+ Unhealthy: "unhealthy",
19
+ };
20
+ })(Value = Checks.Value || (Checks.Value = {}));
21
+ })(Checks = GetDrugSafetyHealthResponse.Checks || (GetDrugSafetyHealthResponse.Checks = {}));
11
22
  })(GetDrugSafetyHealthResponse || (exports.GetDrugSafetyHealthResponse = GetDrugSafetyHealthResponse = {}));
@@ -14,13 +14,11 @@ export interface Alert {
14
14
  /**
15
15
  * Alert source domain and trigger.
16
16
  * - `ae_bbw` — Drug has a Black Box Warning
17
- * - `ddi` — Major (severity 3) or contraindicated (severity 4) interaction
17
+ * - `ddi` — Major (severity 4) or contraindicated (severity 5) interaction
18
18
  * - `pllr_pregnancy` — Pregnancy risk >= 6 (Contraindicated or Absolutely Contraindicated)
19
19
  * - `pllr_lactation` — Lactation risk >= 6
20
20
  * - `clinical_condition` — Clinical condition severity >= 4
21
21
  * - `clinical_population` — Clinical population severity >= 4
22
- * - `allergy_direct` — Product directly matches a supplied patient allergy
23
- * - `allergy_cross_reactivity` — Product cross-reacts with a supplied patient allergy
24
22
  */
25
23
  type: Alert.Type;
26
24
  /** Human-readable alert message (English) */
@@ -48,13 +46,11 @@ export declare namespace Alert {
48
46
  /**
49
47
  * Alert source domain and trigger.
50
48
  * - `ae_bbw` — Drug has a Black Box Warning
51
- * - `ddi` — Major (severity 3) or contraindicated (severity 4) interaction
49
+ * - `ddi` — Major (severity 4) or contraindicated (severity 5) interaction
52
50
  * - `pllr_pregnancy` — Pregnancy risk >= 6 (Contraindicated or Absolutely Contraindicated)
53
51
  * - `pllr_lactation` — Lactation risk >= 6
54
52
  * - `clinical_condition` — Clinical condition severity >= 4
55
53
  * - `clinical_population` — Clinical population severity >= 4
56
- * - `allergy_direct` — Product directly matches a supplied patient allergy
57
- * - `allergy_cross_reactivity` — Product cross-reacts with a supplied patient allergy
58
54
  */
59
55
  const Type: {
60
56
  readonly AeBbw: "ae_bbw";
@@ -63,8 +59,6 @@ export declare namespace Alert {
63
59
  readonly PllrLactation: "pllr_lactation";
64
60
  readonly ClinicalCondition: "clinical_condition";
65
61
  readonly ClinicalPopulation: "clinical_population";
66
- readonly AllergyDirect: "allergy_direct";
67
- readonly AllergyCrossReactivity: "allergy_cross_reactivity";
68
62
  };
69
63
  type Type = (typeof Type)[keyof typeof Type];
70
64
  }
@@ -20,13 +20,11 @@ var Alert;
20
20
  /**
21
21
  * Alert source domain and trigger.
22
22
  * - `ae_bbw` — Drug has a Black Box Warning
23
- * - `ddi` — Major (severity 3) or contraindicated (severity 4) interaction
23
+ * - `ddi` — Major (severity 4) or contraindicated (severity 5) interaction
24
24
  * - `pllr_pregnancy` — Pregnancy risk >= 6 (Contraindicated or Absolutely Contraindicated)
25
25
  * - `pllr_lactation` — Lactation risk >= 6
26
26
  * - `clinical_condition` — Clinical condition severity >= 4
27
27
  * - `clinical_population` — Clinical population severity >= 4
28
- * - `allergy_direct` — Product directly matches a supplied patient allergy
29
- * - `allergy_cross_reactivity` — Product cross-reacts with a supplied patient allergy
30
28
  */
31
29
  Alert.Type = {
32
30
  AeBbw: "ae_bbw",
@@ -35,7 +33,5 @@ var Alert;
35
33
  PllrLactation: "pllr_lactation",
36
34
  ClinicalCondition: "clinical_condition",
37
35
  ClinicalPopulation: "clinical_population",
38
- AllergyDirect: "allergy_direct",
39
- AllergyCrossReactivity: "allergy_cross_reactivity",
40
36
  };
41
37
  })(Alert || (exports.Alert = Alert = {}));
@@ -26,14 +26,6 @@ export interface ClinicalAlert {
26
26
  contraindicated?: boolean | undefined;
27
27
  /** Whether dose adjustment is needed */
28
28
  requires_dose_adjustment?: boolean | undefined;
29
- /** Matched dose-adjustment instruction from the population band, when available. */
30
- dose_adjustment?: (string | null) | undefined;
31
- /** Matched dosing recommendation in English, when available. */
32
- dose_recommendation?: (string | null) | undefined;
33
- /** Matched dosing recommendation in Arabic, when available. */
34
- dose_recommendation_ar?: (string | null) | undefined;
35
- /** Matched renal/hepatic/pediatric context, including the selected band or grade when available. */
36
- matched_context?: Record<string, unknown> | undefined;
37
29
  /** Whether additional monitoring is needed */
38
30
  monitoring_required?: boolean | undefined;
39
31
  /** Clinical rationale (English) */
@@ -1,17 +1,14 @@
1
1
  import type * as SafeRx from "../index.js";
2
2
  /**
3
3
  * Clinical safety considerations combining per-drug population/condition
4
- * data with cross-drug clinical alerts. Without `patient_profile`, the
5
- * API returns product-wide clinical signals; with `patient_profile`, alert
6
- * lists are narrowed to the supplied populations and conditions.
4
+ * data with cross-drug clinical alerts. Enhanced when `patient_profile`
5
+ * is provided in the request.
7
6
  */
8
7
  export interface ClinicalData {
9
8
  /** Per-drug clinical data keyed by sfrx_id */
10
9
  drug_specific?: Record<string, SafeRx.DrugClinicalData> | undefined;
11
- /** Condition-related alerts. Narrowed to `patient_profile.conditions` when supplied; otherwise product-wide condition signals may be returned. */
10
+ /** Cross-drug condition-related alerts (requires `patient_profile.conditions`) */
12
11
  condition_alerts?: SafeRx.ClinicalAlert[] | undefined;
13
- /** Population-related alerts. Narrowed to `patient_profile.populations` when supplied; otherwise product-wide population signals may be returned. */
12
+ /** Cross-drug population-related alerts (requires `patient_profile.populations`) */
14
13
  population_alerts?: SafeRx.ClinicalAlert[] | undefined;
15
- /** Patient context actually applied to clinical-dose matching, including inferred populations from age, renal, or hepatic values. */
16
- context_applied?: SafeRx.ClinicalContextApplied | undefined;
17
14
  }
@@ -1,5 +1,5 @@
1
1
  /**
2
- * Regulatory maximum daily dose data
2
+ * OpenFDA Maximum Daily Dose data
3
3
  */
4
4
  export interface DailyLimit {
5
5
  /** Maximum daily dose in milligrams */
@@ -4,9 +4,8 @@
4
4
  * - `ddi` — Drug-drug interactions (requires 2+ drugs)
5
5
  * - `pllr` — Pregnancy & lactation risk ratings
6
6
  * - `food` — Meal timing & food-drug conflicts
7
- * - `clinical` — Population & condition safety. Without patient context, returns product-wide clinical signals; with `patient_profile`, alerts are narrowed to supplied populations and conditions.
8
- * - `dose` — Dose limits and daily-dose references from the unified dosing data path
9
- * - `allergy` — Patient allergy matching plus direct and cross-reactivity warnings
7
+ * - `clinical` — Population & condition safety (enhanced with `patient_profile`)
8
+ * - `dose` — Maximum daily dose (V3: dual-source, 19K+ products, tier-based safety)
10
9
  */
11
10
  export declare const DomainCode: {
12
11
  readonly Ae: "ae";
@@ -15,6 +14,5 @@ export declare const DomainCode: {
15
14
  readonly Food: "food";
16
15
  readonly Clinical: "clinical";
17
16
  readonly Dose: "dose";
18
- readonly Allergy: "allergy";
19
17
  };
20
18
  export type DomainCode = (typeof DomainCode)[keyof typeof DomainCode];
@@ -8,9 +8,8 @@ exports.DomainCode = void 0;
8
8
  * - `ddi` — Drug-drug interactions (requires 2+ drugs)
9
9
  * - `pllr` — Pregnancy & lactation risk ratings
10
10
  * - `food` — Meal timing & food-drug conflicts
11
- * - `clinical` — Population & condition safety. Without patient context, returns product-wide clinical signals; with `patient_profile`, alerts are narrowed to supplied populations and conditions.
12
- * - `dose` — Dose limits and daily-dose references from the unified dosing data path
13
- * - `allergy` — Patient allergy matching plus direct and cross-reactivity warnings
11
+ * - `clinical` — Population & condition safety (enhanced with `patient_profile`)
12
+ * - `dose` — Maximum daily dose (V3: dual-source, 19K+ products, tier-based safety)
14
13
  */
15
14
  exports.DomainCode = {
16
15
  Ae: "ae",
@@ -19,5 +18,4 @@ exports.DomainCode = {
19
18
  Food: "food",
20
19
  Clinical: "clinical",
21
20
  Dose: "dose",
22
- Allergy: "allergy",
23
21
  };
@@ -1,14 +1,14 @@
1
1
  import type * as SafeRx from "../index.js";
2
2
  /**
3
- * Dose limits and daily-dose reference data from the unified dosing path.
4
- * Includes standard dose summaries, dose limits, daily-limit data when
5
- * available, and caveats for products where calculation needs pharmacist review.
3
+ * Maximum daily dose data from Dose V3 — dual-source system combining
4
+ * WHO Defined Daily Dose (DDD) and OpenFDA Maximum Daily Dose (MDD).
5
+ * Covers 19,341 products (67.7% of database) with tier-based safety calculations.
6
6
  */
7
7
  export interface DosingData {
8
8
  /**
9
9
  * Data quality tier.
10
- * - `1` - Full reference and regulatory daily-limit data available
11
- * - `2` - Regulatory daily-limit data only
10
+ * - `1` — Full reference data (WHO DDD + OpenFDA MDD available)
11
+ * - `2` — Regulatory label data only
12
12
  */
13
13
  tier?: number | undefined;
14
14
  /** Maximum safe units (tablets, capsules) per day */
@@ -25,34 +25,24 @@ export interface DosingData {
25
25
  caveat?: (string | null) | undefined;
26
26
  /** WHO DDD reference dose data */
27
27
  reference_dose?: (SafeRx.ReferenceDose | null) | undefined;
28
- /** Regulatory maximum daily dose data */
28
+ /** OpenFDA maximum daily dose data */
29
29
  daily_limit?: (SafeRx.DailyLimit | null) | undefined;
30
- /** Standard-dose summary when available, including route, frequency, and verification flags. */
31
- standard_dose?: (Record<string, unknown> | null) | undefined;
32
- /** Dose-limit records used by the unified dosing path. */
33
- dose_limits?: Record<string, unknown>[] | undefined;
34
- /** Clinician/patient display summary for dose limits and caveats, when available. */
35
- display_summary?: (Record<string, unknown> | null) | undefined;
36
- /** Calculation uncertainty or review requirement, when available. */
37
- dose_uncertainty?: (Record<string, unknown> | null) | undefined;
38
- /** Display-safe monitoring instructions linked to the dose record, when available. */
39
- monitoring_display?: (Record<string, unknown> | null) | undefined;
40
30
  /** Per-ingredient dose data for combination drugs */
41
31
  components?: ((SafeRx.DoseComponent | null)[] | null) | undefined;
42
32
  /**
43
33
  * Data source for this dose calculation.
44
- * - `reference_standard` — reference dose data only
45
- * - `regulatory_label` — regulatory daily-limit data only
46
- * - `dual_source` — reference and regulatory daily-limit data available
34
+ * - `reference_standard` — WHO DDD only
35
+ * - `regulatory_label` — OpenFDA MDD only
36
+ * - `dual_source` — Both WHO DDD and OpenFDA MDD available
47
37
  */
48
38
  source?: DosingData.Source | undefined;
49
39
  }
50
40
  export declare namespace DosingData {
51
41
  /**
52
42
  * Data source for this dose calculation.
53
- * - `reference_standard` — reference dose data only
54
- * - `regulatory_label` — regulatory daily-limit data only
55
- * - `dual_source` — reference and regulatory daily-limit data available
43
+ * - `reference_standard` — WHO DDD only
44
+ * - `regulatory_label` — OpenFDA MDD only
45
+ * - `dual_source` — Both WHO DDD and OpenFDA MDD available
56
46
  */
57
47
  const Source: {
58
48
  readonly ReferenceStandard: "reference_standard";
@@ -6,9 +6,9 @@ var DosingData;
6
6
  (function (DosingData) {
7
7
  /**
8
8
  * Data source for this dose calculation.
9
- * - `reference_standard` — reference dose data only
10
- * - `regulatory_label` — regulatory daily-limit data only
11
- * - `dual_source` — reference and regulatory daily-limit data available
9
+ * - `reference_standard` — WHO DDD only
10
+ * - `regulatory_label` — OpenFDA MDD only
11
+ * - `dual_source` — Both WHO DDD and OpenFDA MDD available
12
12
  */
13
13
  DosingData.Source = {
14
14
  ReferenceStandard: "reference_standard",
@@ -18,7 +18,6 @@ export interface DrugSafetyCheckResponse {
18
18
  */
19
19
  alerts: SafeRx.Alert[];
20
20
  meta: SafeRx.Meta;
21
- intelligence?: SafeRx.IntelligenceResult | undefined;
22
21
  }
23
22
  export declare namespace DrugSafetyCheckResponse {
24
23
  /** Always `"success"` for 200 responses */
@@ -1,4 +1,3 @@
1
- import type * as SafeRx from "../index.js";
2
1
  export interface ErrorResponse {
3
2
  /** Error indicator or error message */
4
3
  error?: ErrorResponse.Error_ | undefined;
@@ -16,10 +15,6 @@ export interface ErrorResponse {
16
15
  hint?: string | undefined;
17
16
  /** Support email for assistance */
18
17
  support?: string | undefined;
19
- /** Invalid safety domain codes supplied in `include`. */
20
- invalid_domains?: string[] | undefined;
21
- /** Valid safety domain codes. */
22
- valid_domains?: SafeRx.DomainCode[] | undefined;
23
18
  }
24
19
  export declare namespace ErrorResponse {
25
20
  /**
@@ -46,6 +46,8 @@ export interface Interaction {
46
46
  recommendation?: string | undefined;
47
47
  /** Clinical recommendation in Arabic */
48
48
  recommendation_ar?: string | undefined;
49
+ /** Data source */
50
+ source?: string | undefined;
49
51
  }
50
52
  export declare namespace Interaction {
51
53
  /** Human-readable severity label */