pdbe-molstar 3.6.0 → 3.7.1
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/build/pdbe-molstar-component.js +2 -2
- package/build/pdbe-molstar-light.css +2 -2
- package/build/pdbe-molstar-plugin.js +2 -2
- package/build/pdbe-molstar-plugin.js.LICENSE.txt +1 -1
- package/build/pdbe-molstar.css +2 -2
- package/lib/alphafold-transparency.js +7 -8
- package/lib/extensions/complexes/coloring.d.ts +15 -0
- package/lib/extensions/complexes/coloring.js +20 -9
- package/lib/extensions/complexes/index.d.ts +32 -17
- package/lib/extensions/complexes/index.js +24 -48
- package/lib/extensions/complexes/superpose-by-biggest-chain.d.ts +13 -15
- package/lib/extensions/complexes/superpose-by-biggest-chain.js +62 -56
- package/lib/extensions/complexes/superpose-by-sequence-alignment.d.ts +10 -0
- package/lib/extensions/complexes/superpose-by-sequence-alignment.js +181 -0
- package/lib/helpers.d.ts +11 -1
- package/lib/helpers.js +11 -5
- package/lib/plugin-custom-state.d.ts +0 -2
- package/lib/sequence-color/behavior.d.ts +5 -0
- package/lib/sequence-color/behavior.js +54 -0
- package/lib/sequence-color/color.d.ts +11 -0
- package/lib/sequence-color/color.js +58 -0
- package/lib/sequence-color/prop.d.ts +38 -0
- package/lib/sequence-color/prop.js +38 -0
- package/lib/styles/pdbe-molstar/_index.scss +39 -1
- package/lib/superposition.d.ts +2 -2
- package/lib/superposition.js +41 -60
- package/lib/ui/_layout.d.ts +15 -0
- package/lib/ui/_layout.js +162 -0
- package/lib/ui/alphafold-superposition.js +2 -2
- package/lib/ui/layout-no-controls-unless-expanded.d.ts +5 -0
- package/lib/ui/layout-no-controls-unless-expanded.js +34 -0
- package/lib/ui/pdbe-viewport-controls.d.ts +0 -1
- package/lib/ui/pdbe-viewport-controls.js +3 -19
- package/lib/ui/split-ui/components.d.ts +3 -0
- package/lib/ui/split-ui/components.js +3 -0
- package/lib/viewer.d.ts +1 -0
- package/lib/viewer.js +3 -3
- package/package.json +1 -1
- package/lib/superposition-sifts-mapping.d.ts +0 -22
- package/lib/superposition-sifts-mapping.js +0 -153
package/build/pdbe-molstar.css
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/**
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* pdbe-molstar
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* @version 3.
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* @version 3.7.1
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* @link https://github.com/PDBeurope/pdbe-molstar
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* @license Apache 2.0
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*/
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10px;background:#111318;font-weight:bold;display:table-cell;-webkit-user-select:none;-moz-user-select:none;-ms-user-select:none;-o-user-select:none;user-select:none;font-weight:light;cursor:pointer}.msp-plugin .msp-toast-container .msp-toast-entry .msp-toast-message{padding:3px 42px 3px 10px;display:table-cell}.msp-plugin .msp-toast-container .msp-toast-entry .msp-toast-message a{text-decoration:none;color:#68befd;font-weight:bold}.msp-plugin .msp-toast-container .msp-toast-entry .msp-toast-message a:hover{text-decoration:underline;color:hsl(205.3691275168,97.385620915%,50%)}.msp-plugin .msp-toast-container .msp-toast-entry .msp-toast-message a:active,.msp-plugin .msp-toast-container .msp-toast-entry .msp-toast-message a:focus{color:#68befd;outline-offset:0;outline:none}.msp-plugin .msp-toast-container .msp-toast-entry .msp-toast-hide{position:absolute;width:42px;right:0;top:0;bottom:0}.msp-plugin .msp-toast-container .msp-toast-entry .msp-toast-hide 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)}.msp-plugin .msp-plugin-content{color:#ccd4e0}.msp-plugin .msp-plugin-init-error{white-space:pre;margin:10px}.msp-plugin .msp-svg-text{fill:#ccd4e0}.msp-plugin{background:#111318}.msp-plugin ::-webkit-scrollbar-thumb{background-color:rgba(128,128,128,.5019607843);border-radius:10px;border:solid 1px rgba(0,0,0,0);background-clip:content-box}.msp-plugin .msp-plugin-init-error{color:gray}.msp-plugin .msp-layout-static{container-type:size}.msp-plugin .msp-viewport-controls-panel .msp-viewport-controls-panel-controls{max-height:calc(100cqh - 46px - 24px - 10px)}.msp-plugin .msp-simple-help-section{overflow:hidden;text-wrap:nowrap;text-overflow:ellipsis}.msp-plugin .msp-control-group-header button{overflow:hidden;text-wrap:nowrap;text-overflow:ellipsis}.msp-plugin .pdbemolstar-custom-control-viewport-top-left{float:left}.msp-plugin .pdbemolstar-custom-control-viewport-top-left:not(:empty){margin-right:10px}.msp-plugin .pdbemolstar-viewport-top-center-controls{width:100%;display:flex;flex-direction:column;align-items:center;padding-inline:74px;pointer-events:none}.msp-plugin .pdbemolstar-viewport-top-center-controls>*{margin-top:10px;pointer-events:auto;max-width:100%}.msp-plugin .pdbemolstar-overlay{z-index:1000;position:absolute;inset:0px;display:flex;justify-content:center;align-items:center;pointer-events:none}.msp-plugin .pdbemolstar-overlay .pdbemolstar-overlay-box{width:25%;height:25%}.msp-plugin .pdbemolstar-overlay svg.pdbe-animated-logo{background-color:rgba(0,0,0,0);width:100%;height:100%;opacity:80%}.msp-plugin .pdbemolstar-overlay svg.pdbe-animated-logo .path-fg{stroke-dasharray:1812 250;stroke-dashoffset:-250;animation:dash linear normal infinite;animation-duration:5s;animation-delay:1s}@keyframes dash{0%{stroke-dashoffset:1812}80%{stroke-dashoffset:-250}100%{stroke-dashoffset:-250}}.msp-plugin .pdbemolstar-state-gallery-controls{overflow-x:hidden;word-wrap:break-word}.msp-plugin .pdbemolstar-state-gallery-controls:focus-visible{outline:none}.msp-plugin .pdbemolstar-state-gallery-controls .pdbemolstar-state-gallery-state-button{height:24px;line-height:24px;padding-inline:5px;text-align:left;overflow:hidden;text-overflow:ellipsis}.msp-plugin .pdbemolstar-state-gallery-controls .pdbemolstar-state-gallery-state-button .msp-icon{margin-right:3px}.msp-plugin .pdbemolstar-state-gallery-controls .pdbemolstar-state-gallery-legend{margin-block:8px}.msp-plugin .pdbemolstar-state-gallery-controls .pdbemolstar-state-gallery-legend .image_legend_li{margin-left:16px}.msp-plugin .pdbemolstar-state-gallery-controls .pdbemolstar-state-gallery-legend .highlight{font-weight:bold}.msp-plugin .pdbemolstar-state-gallery-title-box{width:500px;max-width:100%;background-color:rgb(11.7134146341,13.0914634146,16.5365853659);display:flex;flex-direction:row;justify-content:space-between;align-items:stretch}.msp-plugin .pdbemolstar-state-gallery-title-box .msp-btn-icon{background-color:rgba(0,0,0,0);height:100%}.msp-plugin .pdbemolstar-state-gallery-title-box .pdbemolstar-state-gallery-title{margin:5px;min-height:2.9em;display:flex;flex-direction:row;align-items:center;text-align:center;font-weight:bold}.msp-plugin .pdbemolstar-state-gallery-title-box .pdbemolstar-state-gallery-title .pdbemolstar-state-gallery-title-icon{width:1.2em}.msp-plugin .pdbemolstar-state-gallery-title-box .pdbemolstar-state-gallery-title .pdbemolstar-state-gallery-title-text{margin-right:1.2em;padding-inline:4px}
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)}.msp-plugin .msp-plugin-content{color:#ccd4e0}.msp-plugin .msp-plugin-init-error{white-space:pre;margin:10px}.msp-plugin .msp-svg-text{fill:#ccd4e0}.msp-plugin{background:#111318}.msp-plugin ::-webkit-scrollbar-thumb{background-color:rgba(128,128,128,.5019607843);border-radius:10px;border:solid 1px rgba(0,0,0,0);background-clip:content-box}.msp-plugin .msp-plugin-init-error{color:gray}.msp-plugin .msp-layout-static{container-type:size}.msp-plugin .msp-viewport-controls-panel .msp-viewport-controls-panel-controls{max-height:calc(100cqh - 46px - 24px - 10px)}.msp-plugin .msp-simple-help-section{overflow:hidden;text-wrap:nowrap;text-overflow:ellipsis}.msp-plugin .msp-control-group-header button{overflow:hidden;text-wrap:nowrap;text-overflow:ellipsis}.msp-plugin .pdbemolstar-custom-control-viewport-top-left{float:left}.msp-plugin .pdbemolstar-custom-control-viewport-top-left:not(:empty){margin-right:10px}.msp-plugin .pdbemolstar-viewport-top-center-controls{width:100%;display:flex;flex-direction:column;align-items:center;padding-inline:82px;pointer-events:none}.msp-plugin .pdbemolstar-viewport-top-center-controls>*{margin-top:10px;pointer-events:auto;max-width:100%}.msp-plugin .pdbemolstar-overlay{z-index:1000;position:absolute;inset:0px;display:flex;justify-content:center;align-items:center;pointer-events:none}.msp-plugin .pdbemolstar-overlay .pdbemolstar-overlay-box{width:25%;height:25%}.msp-plugin .pdbemolstar-overlay svg.pdbe-animated-logo{background-color:rgba(0,0,0,0);width:100%;height:100%;opacity:80%}.msp-plugin .pdbemolstar-overlay svg.pdbe-animated-logo .path-fg{stroke-dasharray:1812 250;stroke-dashoffset:-250;animation:dash linear normal infinite;animation-duration:5s;animation-delay:1s}@keyframes dash{0%{stroke-dashoffset:1812}80%{stroke-dashoffset:-250}100%{stroke-dashoffset:-250}}.msp-plugin .pdbemolstar-state-gallery-controls{overflow-x:hidden;word-wrap:break-word}.msp-plugin .pdbemolstar-state-gallery-controls:focus-visible{outline:none}.msp-plugin .pdbemolstar-state-gallery-controls .pdbemolstar-state-gallery-state-button{height:24px;line-height:24px;padding-inline:5px;text-align:left;overflow:hidden;text-overflow:ellipsis}.msp-plugin .pdbemolstar-state-gallery-controls .pdbemolstar-state-gallery-state-button .msp-icon{margin-right:3px}.msp-plugin .pdbemolstar-state-gallery-controls .pdbemolstar-state-gallery-legend{margin-block:8px}.msp-plugin .pdbemolstar-state-gallery-controls .pdbemolstar-state-gallery-legend .image_legend_li{margin-left:16px}.msp-plugin .pdbemolstar-state-gallery-controls .pdbemolstar-state-gallery-legend .highlight{font-weight:bold}.msp-plugin .pdbemolstar-state-gallery-title-box{width:500px;max-width:100%;background-color:rgb(11.7134146341,13.0914634146,16.5365853659);display:flex;flex-direction:row;justify-content:space-between;align-items:stretch}.msp-plugin .pdbemolstar-state-gallery-title-box .msp-btn-icon{background-color:rgba(0,0,0,0);height:100%}.msp-plugin .pdbemolstar-state-gallery-title-box .pdbemolstar-state-gallery-title{margin:5px;min-height:2.9em;display:flex;flex-direction:row;align-items:center;text-align:center;font-weight:bold}.msp-plugin .pdbemolstar-state-gallery-title-box .pdbemolstar-state-gallery-title .pdbemolstar-state-gallery-title-icon{width:1.2em}.msp-plugin .pdbemolstar-state-gallery-title-box .pdbemolstar-state-gallery-title .pdbemolstar-state-gallery-title-text{margin-right:1.2em;padding-inline:4px}.msp-plugin .msp-viewport-controls-buttons .pdbemolstar-pdbe-link-box{position:absolute;right:0px;width:fit-content}.msp-plugin .msp-viewport-controls-buttons .pdbemolstar-pdbe-link{width:fit-content;min-width:32px;padding-inline:6px;background:rgba(0,0,0,0);display:flex;flex-direction:row;align-items:center}.msp-plugin .msp-viewport-controls-buttons .pdbemolstar-pdbe-logo{height:14px;width:14px;margin-right:3px}.msp-plugin .pdbemolstar-viewport-controls-normal{position:absolute;right:0px;top:0px}.msp-plugin .pdbemolstar-viewport-controls-shifted{position:absolute;right:0px;top:36px}
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@@ -13,7 +13,8 @@ const compiler_1 = require("molstar/lib/mol-script/runtime/query/compiler");
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13
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const mol_state_1 = require("molstar/lib/mol-state");
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const transparency_1 = require("molstar/lib/mol-theme/transparency");
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const TransparencyManagerTag = 'transparency-controls';
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-
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16
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+
/** Select part of the structure with pLDDT <= score. */
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function getLociBelowPLDDT(score, contextData) {
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const queryExp = builder_1.MolScriptBuilder.struct.modifier.union([
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builder_1.MolScriptBuilder.struct.modifier.wholeResidues([
|
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builder_1.MolScriptBuilder.struct.modifier.union([
|
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@@ -28,13 +29,11 @@ function getLociByPLDDT(score, contextData) {
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const sel = query(new structure_1.QueryContext(contextData));
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return structure_1.StructureSelection.toLociWithSourceUnits(sel);
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}
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-
function applyAFTransparency(
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return tslib_1.__awaiter(this,
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-
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-
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-
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}), { canUndo: 'Apply Transparency' });
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-
});
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+
function applyAFTransparency(plugin, structure, transparency, pLDDT = 70) {
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return plugin.dataTransaction((ctx) => tslib_1.__awaiter(this, void 0, void 0, function* () {
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const loci = getLociBelowPLDDT(pLDDT, structure.cell.obj.data);
|
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yield setStructureTransparency(plugin, structure.components, transparency, loci);
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+
}), { canUndo: 'Apply Transparency' });
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}
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function setStructureTransparency(plugin, components, value, loci, types) {
|
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40
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return tslib_1.__awaiter(this, void 0, void 0, function* () {
|
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@@ -9,6 +9,13 @@ export declare function colorComponents(viewer: PDBeMolstarPlugin, params: {
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9
9
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coreColor?: string;
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10
10
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componentColors?: string[];
|
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11
11
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}): Promise<void>;
|
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12
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+
/**
|
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13
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+
Coloring - subcomplexes:
|
|
14
|
+
- base common -> by entity, lighter
|
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15
|
+
- base additional -> gray, lighter
|
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16
|
+
- sub common -> by entity, darker
|
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17
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+
- sub additional -> gray, darker (these are all unmapped components, includes antibodies and ligands)
|
|
18
|
+
*/
|
|
12
19
|
export declare function colorSubcomplex(viewer: PDBeMolstarPlugin, params: {
|
|
13
20
|
baseStructId?: string;
|
|
14
21
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otherStructId?: string;
|
|
@@ -23,6 +30,14 @@ export declare function colorSubcomplex(viewer: PDBeMolstarPlugin, params: {
|
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23
30
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coreColor?: string;
|
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24
31
|
componentColors?: string[];
|
|
25
32
|
}): Promise<void>;
|
|
33
|
+
/**
|
|
34
|
+
Coloring - supercomplexes:
|
|
35
|
+
- base common -> gray, lighter
|
|
36
|
+
- base additional -> unmapped color, lighter (these are all unmapped components, includes antibodies and ligands)
|
|
37
|
+
- super common -> gray, darker
|
|
38
|
+
- super additional mapped -> by entity, darker
|
|
39
|
+
- super additional unmapped -> unmapped color, darker
|
|
40
|
+
*/
|
|
26
41
|
export declare function colorSupercomplex(viewer: PDBeMolstarPlugin, params: {
|
|
27
42
|
baseStructId?: string;
|
|
28
43
|
otherStructId?: string;
|
|
@@ -7,18 +7,14 @@ const tslib_1 = require("tslib");
|
|
|
7
7
|
const color_1 = require("molstar/lib/mol-util/color");
|
|
8
8
|
const helpers_1 = require("../../helpers");
|
|
9
9
|
const DEFAULT_CORE_COLOR = '#d8d8d8';
|
|
10
|
-
const DEFAULT_UNMAPPED_COLOR = '#
|
|
10
|
+
const DEFAULT_UNMAPPED_COLOR = '#f000f0';
|
|
11
11
|
const DEFAULT_COMPONENT_COLORS = [
|
|
12
|
-
'#1b9e77', '#d95f02', '#7570b3', '#
|
|
13
|
-
'#
|
|
14
|
-
'#
|
|
15
|
-
'#e5c494', '#66c2a5', '#fc8d62', '#8da0cb', '#e78ac3', '#a6d854', // Set-2
|
|
12
|
+
'#1b9e77', '#d95f02', '#7570b3', '#66a61e', '#e6ab02', '#a6761d', // Dark-2 without gray and magenta
|
|
13
|
+
'#1f77b4', '#2ca02c', '#d62728', '#927ba7', '#8c564b', '#e377c2', '#bcbd22', '#17becf', // More non-conflicting colors from other palettes
|
|
14
|
+
'#fc8d62', '#9eb9f3', '#ff9da7', '#ffff33', '#8be0a4', '#e15759', '#c69fbb', '#76b7b2', // More non-conflicting colors from other palettes
|
|
16
15
|
];
|
|
17
|
-
// TODO compare color variants:
|
|
18
|
-
// http://127.0.0.1:1339/complexes-demo.html?complexId=PDB-CPX-159519&unmappedColor=%23222222
|
|
19
|
-
// http://127.0.0.1:1339/complexes-demo.html?complexId=PDB-CPX-159519&unmappedColor=%23ff0000
|
|
20
16
|
/** How much lighter/darker colors should be for the base/other complex */
|
|
21
|
-
const COLOR_ADJUSTMENT_STRENGTH = 0.
|
|
17
|
+
const COLOR_ADJUSTMENT_STRENGTH = 0.8;
|
|
22
18
|
function colorComponents(viewer, params) {
|
|
23
19
|
return tslib_1.__awaiter(this, void 0, void 0, function* () {
|
|
24
20
|
const { coreColor = DEFAULT_CORE_COLOR, componentColors = DEFAULT_COMPONENT_COLORS, components, mappings = {} } = params;
|
|
@@ -34,6 +30,13 @@ function colorComponents(viewer, params) {
|
|
|
34
30
|
yield viewer.visual.tooltips({ data: tooltipData, structureId: params.structId });
|
|
35
31
|
});
|
|
36
32
|
}
|
|
33
|
+
/**
|
|
34
|
+
Coloring - subcomplexes:
|
|
35
|
+
- base common -> by entity, lighter
|
|
36
|
+
- base additional -> gray, lighter
|
|
37
|
+
- sub common -> by entity, darker
|
|
38
|
+
- sub additional -> gray, darker (these are all unmapped components, includes antibodies and ligands)
|
|
39
|
+
*/
|
|
37
40
|
function colorSubcomplex(viewer, params) {
|
|
38
41
|
return tslib_1.__awaiter(this, void 0, void 0, function* () {
|
|
39
42
|
const { coreColor = DEFAULT_CORE_COLOR, componentColors = DEFAULT_COMPONENT_COLORS, baseComponents, baseMappings = {}, otherMappings = {} } = params;
|
|
@@ -65,6 +68,14 @@ function colorSubcomplex(viewer, params) {
|
|
|
65
68
|
}
|
|
66
69
|
});
|
|
67
70
|
}
|
|
71
|
+
/**
|
|
72
|
+
Coloring - supercomplexes:
|
|
73
|
+
- base common -> gray, lighter
|
|
74
|
+
- base additional -> unmapped color, lighter (these are all unmapped components, includes antibodies and ligands)
|
|
75
|
+
- super common -> gray, darker
|
|
76
|
+
- super additional mapped -> by entity, darker
|
|
77
|
+
- super additional unmapped -> unmapped color, darker
|
|
78
|
+
*/
|
|
68
79
|
function colorSupercomplex(viewer, params) {
|
|
69
80
|
return tslib_1.__awaiter(this, void 0, void 0, function* () {
|
|
70
81
|
const { coreColor = DEFAULT_CORE_COLOR, unmappedColor = DEFAULT_UNMAPPED_COLOR, componentColors = DEFAULT_COMPONENT_COLORS, baseMappings = {}, otherMappings = {} } = params;
|
|
@@ -1,9 +1,9 @@
|
|
|
1
1
|
/** Helper functions to allow superposition of complexes */
|
|
2
|
-
import {
|
|
2
|
+
import { MinimizeRmsd } from 'molstar/lib/mol-math/linear-algebra/3d/minimize-rmsd';
|
|
3
3
|
import { PDBeMolstarPlugin } from '../..';
|
|
4
4
|
import { QueryParam } from '../../helpers';
|
|
5
|
-
import { SuperpositionResult } from './superpose-by-biggest-chain';
|
|
6
5
|
export * as Coloring from './coloring';
|
|
6
|
+
/** Parameters to `loadComplexSuperposition` */
|
|
7
7
|
export interface LoadComplexSuperpositionParams {
|
|
8
8
|
/** PDB identifier of complex structure */
|
|
9
9
|
pdbId: string;
|
|
@@ -27,29 +27,44 @@ export interface LoadComplexSuperpositionParams {
|
|
|
27
27
|
unmappedColor?: string;
|
|
28
28
|
/** List of colors for coloring unique entities. */
|
|
29
29
|
componentColors?: string[];
|
|
30
|
-
/** Optional specification of which parts of the base complex structure belong to individual Uniprot/Rfam accessions (will be inferred from mmCIF atom_site if not provided)
|
|
30
|
+
/** Optional specification of which parts of the base complex structure belong to individual Uniprot/Rfam accessions (will be inferred from mmCIF atom_site if not provided).
|
|
31
|
+
* It is recommended to provide this for nucleic acids as they don't have mapping in atom_site. */
|
|
31
32
|
baseMappings?: {
|
|
32
33
|
[accession: string]: QueryParam[];
|
|
33
34
|
};
|
|
34
|
-
/** Optional specification of which parts of the other complex structure belong to individual Uniprot/Rfam accessions (will be inferred from mmCIF atom_site if not provided)
|
|
35
|
+
/** Optional specification of which parts of the other complex structure belong to individual Uniprot/Rfam accessions (will be inferred from mmCIF atom_site if not provided).
|
|
36
|
+
* It is recommended to provide this for nucleic acids as they don't have mapping in atom_site. */
|
|
35
37
|
otherMappings?: {
|
|
36
38
|
[accession: string]: QueryParam[];
|
|
37
39
|
};
|
|
38
|
-
/** Superposition method */
|
|
39
|
-
method?: 'biggest-matched-chain' | 'molstar-builtin';
|
|
40
40
|
}
|
|
41
|
-
/**
|
|
42
|
-
export
|
|
41
|
+
/** Result type of `loadComplexSuperposition` */
|
|
42
|
+
export interface LoadComplexSuperpositionResult {
|
|
43
43
|
/** Structure identifier of the newly loaded complex structure, to refer to this structure later */
|
|
44
44
|
id: string;
|
|
45
|
-
/**
|
|
46
|
-
|
|
47
|
-
/** Superposition RMSD and tranform (if status is 'success') */
|
|
48
|
-
superposition: (import("molstar/lib/mol-math/linear-algebra/3d/minimize-rmsd").MinimizeRmsd.Result & {
|
|
49
|
-
nAlignedElements: number;
|
|
50
|
-
}) | undefined;
|
|
45
|
+
/** Superposition RMSD, number of aligned residues, and tranform; if superposition was successful */
|
|
46
|
+
superposition: SuperpositionResult | undefined;
|
|
51
47
|
/** Function that deletes the newly loaded complex structure */
|
|
52
48
|
delete: () => Promise<void>;
|
|
53
|
-
}
|
|
54
|
-
/**
|
|
55
|
-
export
|
|
49
|
+
}
|
|
50
|
+
/** Temporary type until `nAlignedElements` gets into `MinimizeRmsd.Result` in core Molstar */
|
|
51
|
+
export interface SuperpositionResult extends MinimizeRmsd.Result {
|
|
52
|
+
nAlignedElements: number;
|
|
53
|
+
method: 'uniprot-numbering' | 'sequence-alignment';
|
|
54
|
+
accession: string;
|
|
55
|
+
}
|
|
56
|
+
/** Load a structure, superpose onto the main structure based on Uniprot residue numbers (or seq alignment if numbers not available),
|
|
57
|
+
* and optionally apply coloring to show common/additional components.
|
|
58
|
+
*
|
|
59
|
+
* **Superposition method:**
|
|
60
|
+
* Complexes are superposed based on the largest common component (measured the by number of residues) with a UniProt mapping (taken from atom_site mmCIF category).
|
|
61
|
+
* In case there are no common components with Uniprot mapping, the largest common component with an Rfam mapping is used (taken from `baseMappings` and `otherMappings` parameters).
|
|
62
|
+
* Residue-residue correspondence is determined by UniProt residue numbers (for UniProt mappings) or by sequence alignment (for Rfam mappings).
|
|
63
|
+
*
|
|
64
|
+
* **Coloring - subcomplexes:**
|
|
65
|
+
* Common components are colored by entity; additional components are gray. Components in the subcomplex are slightly darkened.
|
|
66
|
+
*
|
|
67
|
+
* **Coloring - supercomplexes:**
|
|
68
|
+
* Common components are gray; mapped additional components are colored by entity; unmapped additional components are magenta. Components in the supercomplex are slightly darkened.
|
|
69
|
+
*/
|
|
70
|
+
export declare function loadComplexSuperposition(viewer: PDBeMolstarPlugin, params: LoadComplexSuperpositionParams): Promise<LoadComplexSuperpositionResult>;
|