p2s_mapper 2.0.0 → 2.1.0
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/README.md +37 -38
- package/dist/alignmentQuality.d.ts +5 -5
- package/dist/alphaFoldModels.d.ts +4 -4
- package/dist/alphaFoldModels.js +4 -4
- package/dist/chooseMappedEntity.d.ts +11 -13
- package/dist/chooseMappedEntity.js +9 -12
- package/dist/chooseMappedEntity.js.map +1 -1
- package/dist/coordinates.d.ts +11 -13
- package/dist/coordinates.js.map +1 -1
- package/dist/extractStructureSequences.d.ts +21 -28
- package/dist/extractStructureSequences.js +2 -2
- package/dist/extractStructureSequences.js.map +1 -1
- package/dist/fetchUtils.d.ts +7 -7
- package/dist/fetchUtils.js +7 -7
- package/dist/isoformRanking.d.ts +1 -1
- package/dist/mappings.d.ts +9 -12
- package/dist/mappings.js +4 -5
- package/dist/mappings.js.map +1 -1
- package/dist/pairwiseAlignment.d.ts +4 -2
- package/dist/pairwiseAlignment.js +9 -7
- package/dist/pairwiseAlignment.js.map +1 -1
- package/dist/pdbUniProtMapping.d.ts +5 -6
- package/dist/pdbUniProtMapping.js +5 -6
- package/dist/pdbUniProtMapping.js.map +1 -1
- package/dist/structureFormat.d.ts +11 -18
- package/dist/structureFormat.js +4 -6
- package/dist/structureFormat.js.map +1 -1
- package/dist/structureSources.d.ts +1 -1
- package/dist/structureUrls.d.ts +11 -16
- package/dist/structureUrls.js +14 -23
- package/dist/structureUrls.js.map +1 -1
- package/dist/types.d.ts +2 -5
- package/dist/types.js +2 -5
- package/dist/types.js.map +1 -1
- package/dist/uniProtSearch.js +3 -8
- package/dist/uniProtSearch.js.map +1 -1
- package/esm/alignmentQuality.d.ts +5 -5
- package/esm/alphaFoldModels.d.ts +4 -4
- package/esm/alphaFoldModels.js +4 -4
- package/esm/chooseMappedEntity.d.ts +11 -13
- package/esm/chooseMappedEntity.js +9 -12
- package/esm/chooseMappedEntity.js.map +1 -1
- package/esm/coordinates.d.ts +11 -13
- package/esm/coordinates.js.map +1 -1
- package/esm/extractStructureSequences.d.ts +21 -28
- package/esm/extractStructureSequences.js +2 -2
- package/esm/extractStructureSequences.js.map +1 -1
- package/esm/fetchUtils.d.ts +7 -7
- package/esm/fetchUtils.js +7 -7
- package/esm/isoformRanking.d.ts +1 -1
- package/esm/mappings.d.ts +9 -12
- package/esm/mappings.js +4 -5
- package/esm/mappings.js.map +1 -1
- package/esm/pairwiseAlignment.d.ts +4 -2
- package/esm/pairwiseAlignment.js +7 -5
- package/esm/pairwiseAlignment.js.map +1 -1
- package/esm/pdbUniProtMapping.d.ts +5 -6
- package/esm/pdbUniProtMapping.js +5 -6
- package/esm/pdbUniProtMapping.js.map +1 -1
- package/esm/structureFormat.d.ts +11 -18
- package/esm/structureFormat.js +4 -6
- package/esm/structureFormat.js.map +1 -1
- package/esm/structureSources.d.ts +1 -1
- package/esm/structureUrls.d.ts +11 -16
- package/esm/structureUrls.js +14 -23
- package/esm/structureUrls.js.map +1 -1
- package/esm/types.d.ts +2 -5
- package/esm/types.js +2 -5
- package/esm/types.js.map +1 -1
- package/esm/uniProtSearch.js +3 -8
- package/esm/uniProtSearch.js.map +1 -1
- package/package.json +1 -1
- package/src/alignmentQuality.ts +5 -5
- package/src/alphaFoldModels.ts +4 -4
- package/src/chooseMappedEntity.ts +12 -15
- package/src/coordinates.ts +11 -13
- package/src/extractStructureSequences.ts +21 -28
- package/src/fetchUtils.ts +7 -7
- package/src/isoformRanking.ts +1 -1
- package/src/mappings.ts +9 -12
- package/src/pairwiseAlignment.ts +11 -8
- package/src/pdbUniProtMapping.ts +5 -6
- package/src/structureFormat.ts +11 -18
- package/src/structureSources.ts +1 -1
- package/src/structureUrls.ts +14 -23
- package/src/types.ts +2 -5
- package/src/uniProtSearch.ts +3 -8
|
@@ -1 +1 @@
|
|
|
1
|
-
{"version":3,"file":"pairwiseAlignment.js","sourceRoot":"","sources":["../src/pairwiseAlignment.ts"],"names":[],"mappings":"AAGA,iEAAiE;AACjE,kBAAkB;AAClB,MAAM,WAAW,GAAG,CAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,CAAC,CAAA;AACrH,kBAAkB;AAClB,MAAM,YAAY,GAAG;IACrB,iGAAiG;IAC/F,CAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAE,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAE,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAE,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,EAAE,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,CAAC,EAAE,IAAI;CACvG,CAAA;AAED,2DAA2D;AAC3D,MAAM,kBAAkB,GAAG,CAAC,CAAC,CAAA;AAE7B,gFAAgF;AAChF,6EAA6E;AAC7E,2EAA2E;AAC3E,MAAM,IAAI,GAAG,WAAW,CAAC,MAAM,CAAA;AAC/B,MAAM,aAAa,GAAG,IAAI,SAAS,CAAC,GAAG,CAAC,CAAC,IAAI,CAAC,CAAC,CAAC,CAAC,CAAA;AACjD,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,IAAI,EAAE,CAAC,EAAE,EAAE,CAAC;IAC9B,MAAM,EAAE,GAAG,WAAW,CAAC,CAAC,CAAE,CAAA;IAC1B,aAAa,CAAC,EAAE,CAAC,UAAU,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,CAAA;IACnC,aAAa,CAAC,EAAE,CAAC,WAAW,EAAE,CAAC,UAAU,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,CAAA;AACnD,CAAC;AACD,MAAM,QAAQ,GAAG,IAAI,SAAS,CAAC,IAAI,GAAG,IAAI,CAAC,CAAA;AAC3C,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,IAAI,EAAE,CAAC,EAAE,EAAE,CAAC;IAC9B,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,IAAI,EAAE,CAAC,EAAE,EAAE,CAAC;QAC9B,QAAQ,CAAC,CAAC,GAAG,IAAI,GAAG,CAAC,CAAC,GAAG,YAAY,CAAC,CAAC,CAAE,CAAC,CAAC,CAAE,CAAA;IAC/C,CAAC;AACH,CAAC;AAED,MAAM,KAAK,GAAG,CAAC,CAAS,EAAE,EAAE;IAC1B,MAAM,IAAI,GAAG,CAAC,CAAC,UAAU,CAAC,CAAC,CAAC,CAAA;IAC5B,OAAO,IAAI,GAAG,GAAG,CAAC,CAAC,CAAC,aAAa,CAAC,IAAI,CAAE,CAAC,CAAC,CAAC,CAAC,CAAC,CAAA;AAC/C,CAAC,CAAA;AAED,SAAS,QAAQ,CAAC,CAAS,EAAE,CAAS;IACpC,MAAM,CAAC,GAAG,KAAK,CAAC,CAAC,CAAC,CAAA;IAClB,MAAM,CAAC,GAAG,KAAK,CAAC,CAAC,CAAC,CAAA;IAClB,OAAO,CAAC,GAAG,CAAC,IAAI,CAAC,GAAG,CAAC,CAAC,CAAC,CAAC,kBAAkB,CAAC,CAAC,CAAC,QAAQ,CAAC,CAAC,GAAG,IAAI,GAAG,CAAC,CAAE,CAAA;AACtE,CAAC;AAED,mDAAmD;AACnD,MAAM,QAAQ,GAAG,CAAC,EAAE,CAAA;AACpB,MAAM,UAAU,GAAG,CAAC,GAAG,CAAA;AAQvB;;;;;;;GAOG;AACH,MAAM,CAAC,MAAM,mBAAmB,GAAG,UAAU,CAAA;AAE7C,MAAM,UAAU,iBAAiB,CAAC,IAAY,EAAE,IAAY;IAC1D,OAAO,CAAC,IAAI,GAAG,CAAC,CAAC,GAAG,CAAC,IAAI,GAAG,CAAC,CAAC,GAAG,mBAAmB,CAAA;AACtD,CAAC;AAED,SAAS,eAAe,CAAC,IAAY,EAAE,IAAY;IACjD,IAAI,iBAAiB,CAAC,IAAI,EAAE,IAAI,CAAC,EAAE,CAAC;QAClC,MAAM,IAAI,KAAK,CACb,gCAAgC,IAAI,MAAM,IAAI,yBAAyB,mBAAmB,cAAc,CACzG,CAAA;IACH,CAAC;AACH,CAAC;AAED,4EAA4E;AAC5E,6EAA6E;AAC7E,+EAA+E;AAC/E,8EAA8E;AAC9E,eAAe;AACf,MAAM,MAAM,GAAG,CAAC,CAAA;AAChB,MAAM,OAAO,GAAG,CAAC,CAAA;AACjB,MAAM,OAAO,GAAG,CAAC,CAAA;AACjB,8EAA8E;AAC9E,MAAM,SAAS,GAAG,CAAC,CAAA;AAEnB,MAAM,OAAO,GAAG,CAAC,CAAA;AACjB,MAAM,QAAQ,GAAG,CAAC,CAAA;AAClB,MAAM,QAAQ,GAAG,CAAC,CAAA;AAKlB,MAAM,WAAW,GAAG,CAAC,KAAiB,EAAE,EAAU,EAAE,KAAa,EAAW,EAAE,CAC5E,CAAC,CAAC,KAAK,CAAC,EAAE,CAAE,IAAI,KAAK,CAAC,GAAG,IAAI,CAAY,CAAA;AAY3C;;;;;GAKG;AACH,SAAS,YAAY,CACnB,IAAY,EACZ,IAAY,EACZ,OAAe,EACf,SAAiB,EACjB,KAAc;IAEd,MAAM,CAAC,GAAG,IAAI,CAAC,MAAM,CAAA;IACrB,MAAM,CAAC,GAAG,IAAI,CAAC,MAAM,CAAA;IACrB,eAAe,CAAC,CAAC,EAAE,CAAC,CAAC,CAAA;IACrB,MAAM,KAAK,GAAG,CAAC,GAAG,CAAC,CAAA;IACnB,MAAM,KAAK,GAAG,IAAI,UAAU,CAAC,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,KAAK,CAAC,CAAA;IAE7C,2EAA2E;IAC3E,oEAAoE;IACpE,IAAI,KAAK,GAAG,IAAI,YAAY,CAAC,KAAK,CAAC,CAAA;IACnC,IAAI,MAAM,GAAG,IAAI,YAAY,CAAC,KAAK,CAAC,CAAC,IAAI,CAAC,CAAC,QAAQ,CAAC,CAAA;IACpD,IAAI,MAAM,GAAG,IAAI,YAAY,CAAC,KAAK,CAAC,CAAC,IAAI,CAAC,CAAC,QAAQ,CAAC,CAAA;IACpD,IAAI,IAAI,GAAG,IAAI,YAAY,CAAC,KAAK,CAAC,CAAA;IAClC,IAAI,KAAK,GAAG,IAAI,YAAY,CAAC,KAAK,CAAC,CAAA;IACnC,IAAI,KAAK,GAAG,IAAI,YAAY,CAAC,KAAK,CAAC,CAAA;IACnC,IAAI,CAAC,KAAK,EAAE,CAAC;QACX,KAAK,CAAC,IAAI,CAAC,CAAC,QAAQ,CAAC,CAAA;QACrB,KAAK,CAAC,CAAC,CAAC,GAAG,CAAC,CAAA;QACZ,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,IAAI,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC;YAC5B,MAAM,CAAC,CAAC,CAAC,GAAG,OAAO,GAAG,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,SAAS,CAAA;QAC3C,CAAC;IACH,CAAC;IAED,IAAI,SAAS,GAAG,KAAK,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,QAAQ,CAAA;IACrC,IAAI,KAAK,GAAG,CAAC,CAAA;IACb,IAAI,KAAK,GAAG,CAAC,CAAA;IACb,IAAI,UAAU,GAAW,MAAM,CAAA;IAE/B,6DAA6D;IAC7D,MAAM,IAAI,GAAG,IAAI,SAAS,CAAC,CAAC,CAAC,CAAA;IAC7B,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC;QAC3B,IAAI,CAAC,CAAC,CAAC,GAAG,KAAK,CAAC,IAAI,CAAC,CAAC,CAAE,CAAC,CAAA;IAC3B,CAAC;IAED,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,IAAI,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC;QAC5B,6BAA6B;QAC7B,IAAI,CAAC,CAAC,CAAC,GAAG,KAAK,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,QAAQ,CAAA;QAC/B,KAAK,CAAC,CAAC,CAAC,GAAG,KAAK,CAAC,CAAC,CAAC,CAAC,QAAQ,CAAC,CAAC,CAAC,OAAO,GAAG,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,SAAS,CAAA;QAC5D,KAAK,CAAC,CAAC,CAAC,GAAG,CAAC,QAAQ,CAAA;QACpB,MAAM,OAAO,GAAG,CAAC,GAAG,KAAK,CAAA;QACzB,MAAM,QAAQ,GAAG,KAAK,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;QACpC,MAAM,SAAS,GAAG,QAAQ,GAAG,IAAI,CAAA;QAEjC,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,IAAI,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC;YAC5B,MAAM,GAAG,GAAG,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAA;YACxB,MAAM,UAAU,GACd,QAAQ,GAAG,CAAC,IAAI,GAAG,GAAG,CAAC;gBACrB,CAAC,CAAC,kBAAkB;gBACpB,CAAC,CAAC,QAAQ,CAAC,SAAS,GAAG,GAAG,CAAE,CAAA;YAEhC,MAAM,EAAE,GAAG,KAAK,CAAC,CAAC,GAAG,CAAC,CAAE,CAAA;YACxB,MAAM,GAAG,GAAG,MAAM,CAAC,CAAC,GAAG,CAAC,CAAE,CAAA;YAC1B,MAAM,GAAG,GAAG,MAAM,CAAC,CAAC,GAAG,CAAC,CAAE,CAAA;YAC1B,kEAAkE;YAClE,MAAM,QAAQ,GAAG,IAAI,CAAC,GAAG,CAAC,EAAE,EAAE,GAAG,EAAE,GAAG,CAAC,CAAA;YACvC,MAAM,QAAQ,GACZ,QAAQ,KAAK,EAAE,CAAC,CAAC,CAAC,MAAM,CAAC,CAAC,CAAC,QAAQ,KAAK,GAAG,CAAC,CAAC,CAAC,OAAO,CAAC,CAAC,CAAC,OAAO,CAAA;YACjE,MAAM,MAAM,GAAG,QAAQ,GAAG,UAAU,CAAA;YACpC,MAAM,OAAO,GAAG,KAAK,IAAI,MAAM,IAAI,CAAC,CAAA;YACpC,IAAI,CAAC,CAAC,CAAC,GAAG,OAAO,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,MAAM,CAAA;YAE9B,MAAM,MAAM,GAAG,KAAK,CAAC,CAAC,CAAE,GAAG,OAAO,CAAA;YAClC,MAAM,QAAQ,GAAG,MAAM,CAAC,CAAC,CAAE,GAAG,SAAS,CAAA;YACvC,KAAK,CAAC,CAAC,CAAC,GAAG,IAAI,CAAC,GAAG,CAAC,MAAM,EAAE,QAAQ,CAAC,CAAA;YAErC,MAAM,MAAM,GAAG,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,GAAG,OAAO,CAAA;YACrC,MAAM,QAAQ,GAAG,KAAK,CAAC,CAAC,GAAG,CAAC,CAAE,GAAG,SAAS,CAAA;YAC1C,KAAK,CAAC,CAAC,CAAC,GAAG,IAAI,CAAC,GAAG,CAAC,MAAM,EAAE,QAAQ,CAAC,CAAA;YAErC,KAAK,CAAC,OAAO,GAAG,CAAC,CAAC;gBAChB,CAAC,CAAC,OAAO,CAAC,CAAC,CAAC,SAAS,CAAC,CAAC,CAAC,QAAQ,CAAC,IAAI,OAAO,CAAC;oBAC7C,CAAC,CAAC,MAAM,IAAI,QAAQ,CAAC,CAAC,CAAC,MAAM,CAAC,CAAC,CAAC,OAAO,CAAC,IAAI,QAAQ,CAAC;oBACrD,CAAC,CAAC,MAAM,IAAI,QAAQ,CAAC,CAAC,CAAC,MAAM,CAAC,CAAC,CAAC,OAAO,CAAC,IAAI,QAAQ,CAAC,CAAA;YAEvD,IAAI,KAAK,EAAE,CAAC;gBACV,MAAM,OAAO,GAAG,IAAI,CAAC,GAAG,CAAC,IAAI,CAAC,CAAC,CAAE,EAAE,KAAK,CAAC,CAAC,CAAE,EAAE,KAAK,CAAC,CAAC,CAAE,CAAC,CAAA;gBACxD,IAAI,OAAO,GAAG,SAAS,EAAE,CAAC;oBACxB,SAAS,GAAG,OAAO,CAAA;oBACnB,KAAK,GAAG,CAAC,CAAA;oBACT,KAAK,GAAG,CAAC,CAAA;oBACT,UAAU;wBACR,OAAO,KAAK,IAAI,CAAC,CAAC,CAAE;4BAClB,CAAC,CAAC,MAAM;4BACR,CAAC,CAAC,OAAO,KAAK,KAAK,CAAC,CAAC,CAAE;gCACrB,CAAC,CAAC,OAAO;gCACT,CAAC,CAAC,OAAO,CAAA;gBACjB,CAAC;YACH,CAAC;QACH,CAAC;QAED,CAAC;QAAA,CAAC,KAAK,EAAE,IAAI,CAAC,GAAG,CAAC,IAAI,EAAE,KAAK,CAAC,CAC7B;QAAA,CAAC,MAAM,EAAE,KAAK,CAAC,GAAG,CAAC,KAAK,EAAE,MAAM,CAAC,CACjC;QAAA,CAAC,MAAM,EAAE,KAAK,CAAC,GAAG,CAAC,KAAK,EAAE,MAAM,CAAC,CAAA;IACpC,CAAC;IAED,IAAI,KAAK,EAAE,CAAC;QACV,OAAO;YACL,KAAK;YACL,KAAK;YACL,KAAK,EAAE,SAAS;YAChB,MAAM,EAAE,KAAK;YACb,MAAM,EAAE,KAAK;YACb,WAAW,EAAE,UAAU;SACxB,CAAA;IACH,CAAC;IACD,yBAAyB;IACzB,MAAM,MAAM,GAAG,KAAK,CAAC,CAAC,CAAE,CAAA;IACxB,MAAM,OAAO,GAAG,MAAM,CAAC,CAAC,CAAE,CAAA;IAC1B,MAAM,OAAO,GAAG,MAAM,CAAC,CAAC,CAAE,CAAA;IAC1B,MAAM,KAAK,GAAG,IAAI,CAAC,GAAG,CAAC,MAAM,EAAE,OAAO,EAAE,OAAO,CAAC,CAAA;IAChD,OAAO;QACL,KAAK;QACL,KAAK;QACL,KAAK;QACL,MAAM,EAAE,CAAC;QACT,MAAM,EAAE,CAAC;QACT,WAAW,EACT,KAAK,KAAK,MAAM,CAAC,CAAC,CAAC,MAAM,CAAC,CAAC,CAAC,KAAK,KAAK,OAAO,CAAC,CAAC,CAAC,OAAO,CAAC,CAAC,CAAC,OAAO;KACpE,CAAA;AACH,CAAC;AAED;;;;GAIG;AACH,SAAS,SAAS,CAChB,IAAY,EACZ,IAAY,EACZ,MAAsB;IAEtB,MAAM,EAAE,KAAK,EAAE,KAAK,EAAE,MAAM,EAAE,MAAM,EAAE,KAAK,EAAE,GAAG,MAAM,CAAA;IACtD,4DAA4D;IAC5D,MAAM,IAAI,GAAa,EAAE,CAAA;IACzB,MAAM,IAAI,GAAa,EAAE,CAAA;IAEzB,uEAAuE;IACvE,gDAAgD;IAChD,KAAK,IAAI,CAAC,GAAG,IAAI,CAAC,MAAM,EAAE,CAAC,GAAG,MAAM,EAAE,CAAC,EAAE,EAAE,CAAC;QAC1C,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;QACvB,IAAI,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;IAChB,CAAC;IACD,KAAK,IAAI,CAAC,GAAG,IAAI,CAAC,MAAM,EAAE,CAAC,GAAG,MAAM,EAAE,CAAC,EAAE,EAAE,CAAC;QAC1C,IAAI,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;QACd,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;IACzB,CAAC;IAED,IAAI,CAAC,GAAG,MAAM,CAAA;IACd,IAAI,CAAC,GAAG,MAAM,CAAA;IACd,IAAI,MAAM,GAAY,MAAM,CAAC,WAAW,CAAA;IACxC,OAAO,CAAC,GAAG,CAAC,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC;QACtB,MAAM,EAAE,GAAG,CAAC,GAAG,KAAK,GAAG,CAAC,CAAA;QACxB,IAAI,MAAM,KAAK,MAAM,EAAE,CAAC;YACtB,MAAM,IAAI,GAAG,WAAW,CAAC,KAAK,EAAE,EAAE,EAAE,OAAO,CAAC,CAAA;YAC5C,IAAI,IAAI,KAAK,SAAS,EAAE,CAAC;gBACvB,MAAK;YACP,CAAC;YACD,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;YACvB,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;YACvB,MAAM,GAAG,IAAI,CAAA;YACb,CAAC,EAAE,CAAA;YACH,CAAC,EAAE,CAAA;QACL,CAAC;aAAM,IAAI,MAAM,KAAK,OAAO,EAAE,CAAC;YAC9B,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;YACvB,IAAI,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;YACd,MAAM,GAAG,WAAW,CAAC,KAAK,EAAE,EAAE,EAAE,QAAQ,CAAC,CAAA;YACzC,CAAC,EAAE,CAAA;QACL,CAAC;aAAM,CAAC;YACN,IAAI,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;YACd,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;YACvB,MAAM,GAAG,WAAW,CAAC,KAAK,EAAE,EAAE,EAAE,QAAQ,CAAC,CAAA;YACzC,CAAC,EAAE,CAAA;QACL,CAAC;IACH,CAAC;IAED,8DAA8D;IAC9D,OAAO,CAAC,GAAG,CAAC,EAAE,CAAC;QACb,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;QACvB,IAAI,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;QACd,CAAC,EAAE,CAAA;IACL,CAAC;IACD,OAAO,CAAC,GAAG,CAAC,EAAE,CAAC;QACb,IAAI,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;QACd,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;QACvB,CAAC,EAAE,CAAA;IACL,CAAC;IAED,OAAO;QACL,WAAW,EAAE,IAAI,CAAC,OAAO,EAAE,CAAC,IAAI,CAAC,EAAE,CAAC;QACpC,WAAW,EAAE,IAAI,CAAC,OAAO,EAAE,CAAC,IAAI,CAAC,EAAE,CAAC;QACpC,KAAK;KACN,CAAA;AACH,CAAC;AAED;;;GAGG;AACH,MAAM,UAAU,eAAe,CAC7B,IAAY,EACZ,IAAY,EACZ,OAAO,GAAG,QAAQ,EAClB,SAAS,GAAG,UAAU;IAEtB,OAAO,SAAS,CACd,IAAI,EACJ,IAAI,EACJ,YAAY,CAAC,IAAI,EAAE,IAAI,EAAE,OAAO,EAAE,SAAS,EAAE,KAAK,CAAC,CACpD,CAAA;AACH,CAAC;AAED;;;GAGG;AACH,MAAM,UAAU,aAAa,CAC3B,IAAY,EACZ,IAAY,EACZ,OAAO,GAAG,QAAQ,EAClB,SAAS,GAAG,UAAU;IAEtB,OAAO,SAAS,CACd,IAAI,EACJ,IAAI,EACJ,YAAY,CAAC,IAAI,EAAE,IAAI,EAAE,OAAO,EAAE,SAAS,EAAE,IAAI,CAAC,CACnD,CAAA;AACH,CAAC;AAED,SAAS,cAAc,CAAC,WAAmB,EAAE,WAAmB;IAC9D,MAAM,KAAK,GAAa,EAAE,CAAA;IAC1B,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,WAAW,CAAC,MAAM,EAAE,CAAC,EAAE,EAAE,CAAC;QAC5C,MAAM,CAAC,GAAG,WAAW,CAAC,CAAC,CAAE,CAAA;QACzB,MAAM,CAAC,GAAG,WAAW,CAAC,CAAC,CAAE,CAAA;QACzB,IAAI,CAAC,KAAK,GAAG,IAAI,CAAC,KAAK,GAAG,IAAI,CAAC,CAAC,WAAW,EAAE,KAAK,CAAC,CAAC,WAAW,EAAE,EAAE,CAAC;YAClE,KAAK,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;QACjB,CAAC;aAAM,IAAI,CAAC,KAAK,GAAG,IAAI,CAAC,KAAK,GAAG,IAAI,QAAQ,CAAC,CAAC,EAAE,CAAC,CAAC,GAAG,CAAC,EAAE,CAAC;YACxD,KAAK,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;QACjB,CAAC;aAAM,CAAC;YACN,KAAK,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;QACjB,CAAC;IACH,CAAC;IACD,OAAO,KAAK,CAAC,IAAI,CAAC,EAAE,CAAC,CAAA;AACvB,CAAC;AAED,8DAA8D;AAC9D,MAAM,UAAU,SAAS,CAAC,GAAW;IACnC,IAAI,KAAK,GAAG,CAAC,CAAA;IACb,KAAK,MAAM,CAAC,IAAI,GAAG,EAAE,CAAC;QACpB,KAAK,IAAI,QAAQ,CAAC,CAAC,EAAE,CAAC,CAAC,CAAA;IACzB,CAAC;IACD,OAAO,KAAK,CAAA;AACd,CAAC;AAED,MAAM,UAAU,eAAe,CAC7B,IAAY,EACZ,IAAY,EACZ,SAA6B;IAE7B,MAAM,EAAE,WAAW,EAAE,WAAW,EAAE,KAAK,EAAE,GACvC,SAAS,KAAK,gBAAgB;QAC5B,CAAC,CAAC,aAAa,CAAC,IAAI,EAAE,IAAI,CAAC;QAC3B,CAAC,CAAC,eAAe,CAAC,IAAI,EAAE,IAAI,CAAC,CAAA;IAEjC,OAAO;QACL,SAAS,EAAE;YACT,SAAS,EAAE,cAAc,CAAC,WAAW,EAAE,WAAW,CAAC;YACnD,IAAI,EAAE;gBACJ,EAAE,EAAE,EAAE,GAAG,EAAE,GAAG,EAAE,WAAW,EAAE;gBAC7B,EAAE,EAAE,EAAE,GAAG,EAAE,GAAG,EAAE,WAAW,EAAE;aAC9B;SACF;QACD,KAAK;KACN,CAAA;AACH,CAAC;AAED,MAAM,UAAU,iBAAiB,CAC/B,IAAY,EACZ,IAAY,EACZ,SAA6B;IAE7B,OAAO,eAAe,CAAC,IAAI,EAAE,IAAI,EAAE,SAAS,CAAC,CAAC,SAAS,CAAA;AACzD,CAAC"}
|
|
1
|
+
{"version":3,"file":"pairwiseAlignment.js","sourceRoot":"","sources":["../src/pairwiseAlignment.ts"],"names":[],"mappings":"AAGA,iEAAiE;AACjE,kBAAkB;AAClB,MAAM,WAAW,GAAG,CAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,EAAC,GAAG,CAAC,CAAA;AACrH,kBAAkB;AAClB,MAAM,YAAY,GAAG;IACrB,iGAAiG;IAC/F,CAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAE,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAE,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAE,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,EAAE,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAE,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,EAAG,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,EAAE,IAAI;IACtG,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAE,CAAC,CAAC,EAAG,CAAC,CAAC,EAAE,IAAI;CACvG,CAAA;AAED,2DAA2D;AAC3D,MAAM,kBAAkB,GAAG,CAAC,CAAC,CAAA;AAE7B,gFAAgF;AAChF,6EAA6E;AAC7E,2EAA2E;AAC3E,MAAM,IAAI,GAAG,WAAW,CAAC,MAAM,CAAA;AAC/B,MAAM,aAAa,GAAG,IAAI,SAAS,CAAC,GAAG,CAAC,CAAC,IAAI,CAAC,CAAC,CAAC,CAAC,CAAA;AACjD,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,IAAI,EAAE,CAAC,EAAE,EAAE,CAAC;IAC9B,MAAM,EAAE,GAAG,WAAW,CAAC,CAAC,CAAE,CAAA;IAC1B,aAAa,CAAC,EAAE,CAAC,UAAU,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,CAAA;IACnC,aAAa,CAAC,EAAE,CAAC,WAAW,EAAE,CAAC,UAAU,CAAC,CAAC,CAAC,CAAC,GAAG,CAAC,CAAA;AACnD,CAAC;AACD,MAAM,QAAQ,GAAG,IAAI,SAAS,CAAC,IAAI,GAAG,IAAI,CAAC,CAAA;AAC3C,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,IAAI,EAAE,CAAC,EAAE,EAAE,CAAC;IAC9B,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,IAAI,EAAE,CAAC,EAAE,EAAE,CAAC;QAC9B,QAAQ,CAAC,CAAC,GAAG,IAAI,GAAG,CAAC,CAAC,GAAG,YAAY,CAAC,CAAC,CAAE,CAAC,CAAC,CAAE,CAAA;IAC/C,CAAC;AACH,CAAC;AAED,MAAM,KAAK,GAAG,CAAC,CAAS,EAAE,EAAE;IAC1B,MAAM,IAAI,GAAG,CAAC,CAAC,UAAU,CAAC,CAAC,CAAC,CAAA;IAC5B,OAAO,IAAI,GAAG,GAAG,CAAC,CAAC,CAAC,aAAa,CAAC,IAAI,CAAE,CAAC,CAAC,CAAC,CAAC,CAAC,CAAA;AAC/C,CAAC,CAAA;AAED,SAAS,QAAQ,CAAC,CAAS,EAAE,CAAS;IACpC,MAAM,CAAC,GAAG,KAAK,CAAC,CAAC,CAAC,CAAA;IAClB,MAAM,CAAC,GAAG,KAAK,CAAC,CAAC,CAAC,CAAA;IAClB,OAAO,CAAC,GAAG,CAAC,IAAI,CAAC,GAAG,CAAC,CAAC,CAAC,CAAC,kBAAkB,CAAC,CAAC,CAAC,QAAQ,CAAC,CAAC,GAAG,IAAI,GAAG,CAAC,CAAE,CAAA;AACtE,CAAC;AAED,mDAAmD;AACnD,MAAM,QAAQ,GAAG,CAAC,EAAE,CAAA;AACpB,MAAM,UAAU,GAAG,CAAC,GAAG,CAAA;AAQvB;;;;;;;GAOG;AACH,MAAM,CAAC,MAAM,mBAAmB,GAAG,UAAU,CAAA;AAE7C,MAAM,UAAU,iBAAiB,CAAC,IAAY,EAAE,IAAY;IAC1D,OAAO,CAAC,IAAI,GAAG,CAAC,CAAC,GAAG,CAAC,IAAI,GAAG,CAAC,CAAC,GAAG,mBAAmB,CAAA;AACtD,CAAC;AAED,SAAS,eAAe,CAAC,IAAY,EAAE,IAAY;IACjD,IAAI,iBAAiB,CAAC,IAAI,EAAE,IAAI,CAAC,EAAE,CAAC;QAClC,MAAM,IAAI,KAAK,CACb,gCAAgC,IAAI,MAAM,IAAI,yBAAyB,mBAAmB,cAAc,CACzG,CAAA;IACH,CAAC;AACH,CAAC;AAED,4EAA4E;AAC5E,6EAA6E;AAC7E,+EAA+E;AAC/E,8EAA8E;AAC9E,eAAe;AACf,MAAM,MAAM,GAAG,CAAC,CAAA;AAChB,MAAM,OAAO,GAAG,CAAC,CAAA;AACjB,MAAM,OAAO,GAAG,CAAC,CAAA;AACjB,8EAA8E;AAC9E,MAAM,SAAS,GAAG,CAAC,CAAA;AAEnB,MAAM,OAAO,GAAG,CAAC,CAAA;AACjB,MAAM,QAAQ,GAAG,CAAC,CAAA;AAClB,MAAM,QAAQ,GAAG,CAAC,CAAA;AAKlB,MAAM,WAAW,GAAG,CAAC,KAAiB,EAAE,EAAU,EAAE,KAAa,EAAW,EAAE,CAC5E,CAAC,CAAC,KAAK,CAAC,EAAE,CAAE,IAAI,KAAK,CAAC,GAAG,IAAI,CAAY,CAAA;AAY3C;;;;;GAKG;AACH,SAAS,YAAY,CACnB,IAAY,EACZ,IAAY,EACZ,OAAe,EACf,SAAiB,EACjB,KAAc;IAEd,MAAM,CAAC,GAAG,IAAI,CAAC,MAAM,CAAA;IACrB,MAAM,CAAC,GAAG,IAAI,CAAC,MAAM,CAAA;IACrB,eAAe,CAAC,CAAC,EAAE,CAAC,CAAC,CAAA;IACrB,MAAM,KAAK,GAAG,CAAC,GAAG,CAAC,CAAA;IACnB,MAAM,KAAK,GAAG,IAAI,UAAU,CAAC,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,KAAK,CAAC,CAAA;IAE7C,2EAA2E;IAC3E,oEAAoE;IACpE,IAAI,KAAK,GAAG,IAAI,YAAY,CAAC,KAAK,CAAC,CAAA;IACnC,IAAI,MAAM,GAAG,IAAI,YAAY,CAAC,KAAK,CAAC,CAAC,IAAI,CAAC,CAAC,QAAQ,CAAC,CAAA;IACpD,IAAI,MAAM,GAAG,IAAI,YAAY,CAAC,KAAK,CAAC,CAAC,IAAI,CAAC,CAAC,QAAQ,CAAC,CAAA;IACpD,IAAI,IAAI,GAAG,IAAI,YAAY,CAAC,KAAK,CAAC,CAAA;IAClC,IAAI,KAAK,GAAG,IAAI,YAAY,CAAC,KAAK,CAAC,CAAA;IACnC,IAAI,KAAK,GAAG,IAAI,YAAY,CAAC,KAAK,CAAC,CAAA;IACnC,IAAI,CAAC,KAAK,EAAE,CAAC;QACX,KAAK,CAAC,IAAI,CAAC,CAAC,QAAQ,CAAC,CAAA;QACrB,KAAK,CAAC,CAAC,CAAC,GAAG,CAAC,CAAA;QACZ,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,IAAI,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC;YAC5B,MAAM,CAAC,CAAC,CAAC,GAAG,OAAO,GAAG,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,SAAS,CAAA;QAC3C,CAAC;IACH,CAAC;IAED,IAAI,SAAS,GAAG,KAAK,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,QAAQ,CAAA;IACrC,IAAI,KAAK,GAAG,CAAC,CAAA;IACb,IAAI,KAAK,GAAG,CAAC,CAAA;IACb,IAAI,UAAU,GAAW,MAAM,CAAA;IAE/B,6DAA6D;IAC7D,MAAM,IAAI,GAAG,IAAI,SAAS,CAAC,CAAC,CAAC,CAAA;IAC7B,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC;QAC3B,IAAI,CAAC,CAAC,CAAC,GAAG,KAAK,CAAC,IAAI,CAAC,CAAC,CAAE,CAAC,CAAA;IAC3B,CAAC;IAED,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,IAAI,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC;QAC5B,6BAA6B;QAC7B,IAAI,CAAC,CAAC,CAAC,GAAG,KAAK,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,QAAQ,CAAA;QAC/B,KAAK,CAAC,CAAC,CAAC,GAAG,KAAK,CAAC,CAAC,CAAC,CAAC,QAAQ,CAAC,CAAC,CAAC,OAAO,GAAG,CAAC,CAAC,GAAG,CAAC,CAAC,GAAG,SAAS,CAAA;QAC5D,KAAK,CAAC,CAAC,CAAC,GAAG,CAAC,QAAQ,CAAA;QACpB,MAAM,OAAO,GAAG,CAAC,GAAG,KAAK,CAAA;QACzB,MAAM,QAAQ,GAAG,KAAK,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;QACpC,MAAM,SAAS,GAAG,QAAQ,GAAG,IAAI,CAAA;QAEjC,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,IAAI,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC;YAC5B,MAAM,GAAG,GAAG,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAA;YACxB,MAAM,UAAU,GACd,QAAQ,GAAG,CAAC,IAAI,GAAG,GAAG,CAAC;gBACrB,CAAC,CAAC,kBAAkB;gBACpB,CAAC,CAAC,QAAQ,CAAC,SAAS,GAAG,GAAG,CAAE,CAAA;YAEhC,MAAM,EAAE,GAAG,KAAK,CAAC,CAAC,GAAG,CAAC,CAAE,CAAA;YACxB,MAAM,GAAG,GAAG,MAAM,CAAC,CAAC,GAAG,CAAC,CAAE,CAAA;YAC1B,MAAM,GAAG,GAAG,MAAM,CAAC,CAAC,GAAG,CAAC,CAAE,CAAA;YAC1B,kEAAkE;YAClE,MAAM,QAAQ,GAAG,IAAI,CAAC,GAAG,CAAC,EAAE,EAAE,GAAG,EAAE,GAAG,CAAC,CAAA;YACvC,MAAM,QAAQ,GACZ,QAAQ,KAAK,EAAE,CAAC,CAAC,CAAC,MAAM,CAAC,CAAC,CAAC,QAAQ,KAAK,GAAG,CAAC,CAAC,CAAC,OAAO,CAAC,CAAC,CAAC,OAAO,CAAA;YACjE,MAAM,MAAM,GAAG,QAAQ,GAAG,UAAU,CAAA;YACpC,MAAM,OAAO,GAAG,KAAK,IAAI,MAAM,IAAI,CAAC,CAAA;YACpC,IAAI,CAAC,CAAC,CAAC,GAAG,OAAO,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,MAAM,CAAA;YAE9B,MAAM,MAAM,GAAG,KAAK,CAAC,CAAC,CAAE,GAAG,OAAO,CAAA;YAClC,MAAM,QAAQ,GAAG,MAAM,CAAC,CAAC,CAAE,GAAG,SAAS,CAAA;YACvC,KAAK,CAAC,CAAC,CAAC,GAAG,IAAI,CAAC,GAAG,CAAC,MAAM,EAAE,QAAQ,CAAC,CAAA;YAErC,MAAM,MAAM,GAAG,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,GAAG,OAAO,CAAA;YACrC,MAAM,QAAQ,GAAG,KAAK,CAAC,CAAC,GAAG,CAAC,CAAE,GAAG,SAAS,CAAA;YAC1C,KAAK,CAAC,CAAC,CAAC,GAAG,IAAI,CAAC,GAAG,CAAC,MAAM,EAAE,QAAQ,CAAC,CAAA;YAErC,KAAK,CAAC,OAAO,GAAG,CAAC,CAAC;gBAChB,CAAC,CAAC,OAAO,CAAC,CAAC,CAAC,SAAS,CAAC,CAAC,CAAC,QAAQ,CAAC,IAAI,OAAO,CAAC;oBAC7C,CAAC,CAAC,MAAM,IAAI,QAAQ,CAAC,CAAC,CAAC,MAAM,CAAC,CAAC,CAAC,OAAO,CAAC,IAAI,QAAQ,CAAC;oBACrD,CAAC,CAAC,MAAM,IAAI,QAAQ,CAAC,CAAC,CAAC,MAAM,CAAC,CAAC,CAAC,OAAO,CAAC,IAAI,QAAQ,CAAC,CAAA;YAEvD,IAAI,KAAK,EAAE,CAAC;gBACV,MAAM,OAAO,GAAG,IAAI,CAAC,GAAG,CAAC,IAAI,CAAC,CAAC,CAAE,EAAE,KAAK,CAAC,CAAC,CAAE,EAAE,KAAK,CAAC,CAAC,CAAE,CAAC,CAAA;gBACxD,IAAI,OAAO,GAAG,SAAS,EAAE,CAAC;oBACxB,SAAS,GAAG,OAAO,CAAA;oBACnB,KAAK,GAAG,CAAC,CAAA;oBACT,KAAK,GAAG,CAAC,CAAA;oBACT,UAAU;wBACR,OAAO,KAAK,IAAI,CAAC,CAAC,CAAE;4BAClB,CAAC,CAAC,MAAM;4BACR,CAAC,CAAC,OAAO,KAAK,KAAK,CAAC,CAAC,CAAE;gCACrB,CAAC,CAAC,OAAO;gCACT,CAAC,CAAC,OAAO,CAAA;gBACjB,CAAC;YACH,CAAC;QACH,CAAC;QAED,CAAC;QAAA,CAAC,KAAK,EAAE,IAAI,CAAC,GAAG,CAAC,IAAI,EAAE,KAAK,CAAC,CAC7B;QAAA,CAAC,MAAM,EAAE,KAAK,CAAC,GAAG,CAAC,KAAK,EAAE,MAAM,CAAC,CACjC;QAAA,CAAC,MAAM,EAAE,KAAK,CAAC,GAAG,CAAC,KAAK,EAAE,MAAM,CAAC,CAAA;IACpC,CAAC;IAED,IAAI,KAAK,EAAE,CAAC;QACV,OAAO;YACL,KAAK;YACL,KAAK;YACL,KAAK,EAAE,SAAS;YAChB,MAAM,EAAE,KAAK;YACb,MAAM,EAAE,KAAK;YACb,WAAW,EAAE,UAAU;SACxB,CAAA;IACH,CAAC;IACD,yBAAyB;IACzB,MAAM,MAAM,GAAG,KAAK,CAAC,CAAC,CAAE,CAAA;IACxB,MAAM,OAAO,GAAG,MAAM,CAAC,CAAC,CAAE,CAAA;IAC1B,MAAM,OAAO,GAAG,MAAM,CAAC,CAAC,CAAE,CAAA;IAC1B,MAAM,KAAK,GAAG,IAAI,CAAC,GAAG,CAAC,MAAM,EAAE,OAAO,EAAE,OAAO,CAAC,CAAA;IAChD,OAAO;QACL,KAAK;QACL,KAAK;QACL,KAAK;QACL,MAAM,EAAE,CAAC;QACT,MAAM,EAAE,CAAC;QACT,WAAW,EACT,KAAK,KAAK,MAAM,CAAC,CAAC,CAAC,MAAM,CAAC,CAAC,CAAC,KAAK,KAAK,OAAO,CAAC,CAAC,CAAC,OAAO,CAAC,CAAC,CAAC,OAAO;KACpE,CAAA;AACH,CAAC;AAED;;;;GAIG;AACH,SAAS,SAAS,CAChB,IAAY,EACZ,IAAY,EACZ,MAAsB;IAEtB,MAAM,EAAE,KAAK,EAAE,KAAK,EAAE,MAAM,EAAE,MAAM,EAAE,KAAK,EAAE,GAAG,MAAM,CAAA;IACtD,4DAA4D;IAC5D,MAAM,IAAI,GAAa,EAAE,CAAA;IACzB,MAAM,IAAI,GAAa,EAAE,CAAA;IAEzB,uEAAuE;IACvE,gDAAgD;IAChD,KAAK,IAAI,CAAC,GAAG,IAAI,CAAC,MAAM,EAAE,CAAC,GAAG,MAAM,EAAE,CAAC,EAAE,EAAE,CAAC;QAC1C,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;QACvB,IAAI,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;IAChB,CAAC;IACD,KAAK,IAAI,CAAC,GAAG,IAAI,CAAC,MAAM,EAAE,CAAC,GAAG,MAAM,EAAE,CAAC,EAAE,EAAE,CAAC;QAC1C,IAAI,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;QACd,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;IACzB,CAAC;IAED,IAAI,CAAC,GAAG,MAAM,CAAA;IACd,IAAI,CAAC,GAAG,MAAM,CAAA;IACd,IAAI,MAAM,GAAY,MAAM,CAAC,WAAW,CAAA;IACxC,OAAO,CAAC,GAAG,CAAC,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC;QACtB,MAAM,EAAE,GAAG,CAAC,GAAG,KAAK,GAAG,CAAC,CAAA;QACxB,IAAI,MAAM,KAAK,MAAM,EAAE,CAAC;YACtB,MAAM,IAAI,GAAG,WAAW,CAAC,KAAK,EAAE,EAAE,EAAE,OAAO,CAAC,CAAA;YAC5C,IAAI,IAAI,KAAK,SAAS,EAAE,CAAC;gBACvB,MAAK;YACP,CAAC;YACD,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;YACvB,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;YACvB,MAAM,GAAG,IAAI,CAAA;YACb,CAAC,EAAE,CAAA;YACH,CAAC,EAAE,CAAA;QACL,CAAC;aAAM,IAAI,MAAM,KAAK,OAAO,EAAE,CAAC;YAC9B,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;YACvB,IAAI,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;YACd,MAAM,GAAG,WAAW,CAAC,KAAK,EAAE,EAAE,EAAE,QAAQ,CAAC,CAAA;YACzC,CAAC,EAAE,CAAA;QACL,CAAC;aAAM,CAAC;YACN,IAAI,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;YACd,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;YACvB,MAAM,GAAG,WAAW,CAAC,KAAK,EAAE,EAAE,EAAE,QAAQ,CAAC,CAAA;YACzC,CAAC,EAAE,CAAA;QACL,CAAC;IACH,CAAC;IAED,8DAA8D;IAC9D,OAAO,CAAC,GAAG,CAAC,EAAE,CAAC;QACb,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;QACvB,IAAI,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;QACd,CAAC,EAAE,CAAA;IACL,CAAC;IACD,OAAO,CAAC,GAAG,CAAC,EAAE,CAAC;QACb,IAAI,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;QACd,IAAI,CAAC,IAAI,CAAC,IAAI,CAAC,CAAC,GAAG,CAAC,CAAE,CAAC,CAAA;QACvB,CAAC,EAAE,CAAA;IACL,CAAC;IAED,OAAO;QACL,WAAW,EAAE,IAAI,CAAC,OAAO,EAAE,CAAC,IAAI,CAAC,EAAE,CAAC;QACpC,WAAW,EAAE,IAAI,CAAC,OAAO,EAAE,CAAC,IAAI,CAAC,EAAE,CAAC;QACpC,KAAK;KACN,CAAA;AACH,CAAC;AAED;;;GAGG;AACH,MAAM,UAAU,eAAe,CAC7B,IAAY,EACZ,IAAY,EACZ,OAAO,GAAG,QAAQ,EAClB,SAAS,GAAG,UAAU;IAEtB,OAAO,SAAS,CACd,IAAI,EACJ,IAAI,EACJ,YAAY,CAAC,IAAI,EAAE,IAAI,EAAE,OAAO,EAAE,SAAS,EAAE,KAAK,CAAC,CACpD,CAAA;AACH,CAAC;AAED;;;GAGG;AACH,MAAM,UAAU,aAAa,CAC3B,IAAY,EACZ,IAAY,EACZ,OAAO,GAAG,QAAQ,EAClB,SAAS,GAAG,UAAU;IAEtB,OAAO,SAAS,CACd,IAAI,EACJ,IAAI,EACJ,YAAY,CAAC,IAAI,EAAE,IAAI,EAAE,OAAO,EAAE,SAAS,EAAE,IAAI,CAAC,CACnD,CAAA;AACH,CAAC;AAED,SAAS,cAAc,CAAC,WAAmB,EAAE,WAAmB;IAC9D,MAAM,KAAK,GAAa,EAAE,CAAA;IAC1B,KAAK,IAAI,CAAC,GAAG,CAAC,EAAE,CAAC,GAAG,WAAW,CAAC,MAAM,EAAE,CAAC,EAAE,EAAE,CAAC;QAC5C,MAAM,CAAC,GAAG,WAAW,CAAC,CAAC,CAAE,CAAA;QACzB,MAAM,CAAC,GAAG,WAAW,CAAC,CAAC,CAAE,CAAA;QACzB,IAAI,CAAC,KAAK,GAAG,IAAI,CAAC,KAAK,GAAG,IAAI,CAAC,CAAC,WAAW,EAAE,KAAK,CAAC,CAAC,WAAW,EAAE,EAAE,CAAC;YAClE,KAAK,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;QACjB,CAAC;aAAM,IAAI,CAAC,KAAK,GAAG,IAAI,CAAC,KAAK,GAAG,IAAI,QAAQ,CAAC,CAAC,EAAE,CAAC,CAAC,GAAG,CAAC,EAAE,CAAC;YACxD,KAAK,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;QACjB,CAAC;aAAM,CAAC;YACN,KAAK,CAAC,IAAI,CAAC,GAAG,CAAC,CAAA;QACjB,CAAC;IACH,CAAC;IACD,OAAO,KAAK,CAAC,IAAI,CAAC,EAAE,CAAC,CAAA;AACvB,CAAC;AAED,8DAA8D;AAC9D,MAAM,UAAU,SAAS,CAAC,GAAW;IACnC,IAAI,KAAK,GAAG,CAAC,CAAA;IACb,KAAK,MAAM,CAAC,IAAI,GAAG,EAAE,CAAC;QACpB,KAAK,IAAI,QAAQ,CAAC,CAAC,EAAE,CAAC,CAAC,CAAA;IACzB,CAAC;IACD,OAAO,KAAK,CAAA;AACd,CAAC;AAED,MAAM,UAAU,eAAe,CAC7B,UAAkB,EAClB,SAAiB,EACjB,SAA6B;IAE7B,MAAM,EAAE,WAAW,EAAE,WAAW,EAAE,KAAK,EAAE,GACvC,SAAS,KAAK,gBAAgB;QAC5B,CAAC,CAAC,aAAa,CAAC,UAAU,EAAE,SAAS,CAAC;QACtC,CAAC,CAAC,eAAe,CAAC,UAAU,EAAE,SAAS,CAAC,CAAA;IAE5C,OAAO;QACL,SAAS,EAAE;YACT,SAAS,EAAE,cAAc,CAAC,WAAW,EAAE,WAAW,CAAC;YACnD,IAAI,EAAE;gBACJ,EAAE,EAAE,EAAE,GAAG,EAAE,GAAG,EAAE,WAAW,EAAE;gBAC7B,EAAE,EAAE,EAAE,GAAG,EAAE,GAAG,EAAE,WAAW,EAAE;aAC9B;SACF;QACD,KAAK;KACN,CAAA;AACH,CAAC;AAED,MAAM,UAAU,cAAc,CAC5B,UAAkB,EAClB,SAAiB,EACjB,SAA6B;IAE7B,OAAO,eAAe,CAAC,UAAU,EAAE,SAAS,EAAE,SAAS,CAAC,CAAC,SAAS,CAAA;AACpE,CAAC;AAED,2EAA2E;AAC3E,MAAM,CAAC,MAAM,iBAAiB,GAAG,cAAc,CAAA"}
|
|
@@ -29,12 +29,11 @@ export interface SegmentEntity {
|
|
|
29
29
|
chains: readonly string[];
|
|
30
30
|
}
|
|
31
31
|
/**
|
|
32
|
-
* Picks the UniProt entry
|
|
33
|
-
*
|
|
34
|
-
*
|
|
35
|
-
*
|
|
36
|
-
*
|
|
37
|
-
* contributing the most residues wins.
|
|
32
|
+
* Picks the UniProt entry for a given entity, with its segments narrowed to
|
|
33
|
+
* that entity. Pass the entity mapped to the transcript: a heteromer's chains
|
|
34
|
+
* align to different accessions, and the wrong one would annotate the wrong
|
|
35
|
+
* protein. When several accessions cover one entity (a chimeric construct), the
|
|
36
|
+
* one covering the most residues wins.
|
|
38
37
|
*/
|
|
39
38
|
export declare function chooseUniProtMappingForEntity(mappings: UniProtStructureMapping[], entity: SegmentEntity | undefined): UniProtStructureMapping | undefined;
|
|
40
39
|
/**
|
package/esm/pdbUniProtMapping.js
CHANGED
|
@@ -26,12 +26,11 @@ function segmentsForEntity(mapping, entity) {
|
|
|
26
26
|
: entity.chains.includes(s.chainId)));
|
|
27
27
|
}
|
|
28
28
|
/**
|
|
29
|
-
* Picks the UniProt entry
|
|
30
|
-
*
|
|
31
|
-
*
|
|
32
|
-
*
|
|
33
|
-
*
|
|
34
|
-
* contributing the most residues wins.
|
|
29
|
+
* Picks the UniProt entry for a given entity, with its segments narrowed to
|
|
30
|
+
* that entity. Pass the entity mapped to the transcript: a heteromer's chains
|
|
31
|
+
* align to different accessions, and the wrong one would annotate the wrong
|
|
32
|
+
* protein. When several accessions cover one entity (a chimeric construct), the
|
|
33
|
+
* one covering the most residues wins.
|
|
35
34
|
*/
|
|
36
35
|
export function chooseUniProtMappingForEntity(mappings, entity) {
|
|
37
36
|
if (entity === undefined) {
|
|
@@ -1 +1 @@
|
|
|
1
|
-
{"version":3,"file":"pdbUniProtMapping.js","sourceRoot":"","sources":["../src/pdbUniProtMapping.ts"],"names":[],"mappings":"AAAA,mCAAmC;AACnC,EAAE;AACF,+EAA+E;AAC/E,iFAAiF;AACjF,+EAA+E;AAC/E,6EAA6E;AAC7E,6EAA6E;AAC7E,2EAA2E;AAC3E,8EAA8E;AAC9E,sDAAsD;AACtD,EAAE;AACF,kEAAkE;AAClE,yEAAyE;AA6BzE,SAAS,eAAe,CAAC,QAAmC;IAC1D,OAAO,QAAQ,CAAC,MAAM,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,SAAS,GAAG,CAAC,CAAC,WAAW,GAAG,CAAC,CAAC,EAAE,CAAC,CAAC,CAAA;AAC5E,CAAC;AASD;;;;;GAKG;AACH,SAAS,iBAAiB,CACxB,OAAgC,EAChC,MAAqB;IAErB,OAAO,cAAc,CACnB,OAAO,CAAC,QAAQ,CAAC,MAAM,CAAC,CAAC,CAAC,EAAE,CAC1B,CAAC,CAAC,OAAO,KAAK,SAAS;QACrB,CAAC,CAAC,CAAC,CAAC,QAAQ,KAAK,MAAM,CAAC,QAAQ;QAChC,CAAC,CAAC,MAAM,CAAC,MAAM,CAAC,QAAQ,CAAC,CAAC,CAAC,OAAO,CAAC,CACtC,CACF,CAAA;AACH,CAAC;AAED
|
|
1
|
+
{"version":3,"file":"pdbUniProtMapping.js","sourceRoot":"","sources":["../src/pdbUniProtMapping.ts"],"names":[],"mappings":"AAAA,mCAAmC;AACnC,EAAE;AACF,+EAA+E;AAC/E,iFAAiF;AACjF,+EAA+E;AAC/E,6EAA6E;AAC7E,6EAA6E;AAC7E,2EAA2E;AAC3E,8EAA8E;AAC9E,sDAAsD;AACtD,EAAE;AACF,kEAAkE;AAClE,yEAAyE;AA6BzE,SAAS,eAAe,CAAC,QAAmC;IAC1D,OAAO,QAAQ,CAAC,MAAM,CAAC,CAAC,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,SAAS,GAAG,CAAC,CAAC,WAAW,GAAG,CAAC,CAAC,EAAE,CAAC,CAAC,CAAA;AAC5E,CAAC;AASD;;;;;GAKG;AACH,SAAS,iBAAiB,CACxB,OAAgC,EAChC,MAAqB;IAErB,OAAO,cAAc,CACnB,OAAO,CAAC,QAAQ,CAAC,MAAM,CAAC,CAAC,CAAC,EAAE,CAC1B,CAAC,CAAC,OAAO,KAAK,SAAS;QACrB,CAAC,CAAC,CAAC,CAAC,QAAQ,KAAK,MAAM,CAAC,QAAQ;QAChC,CAAC,CAAC,MAAM,CAAC,MAAM,CAAC,QAAQ,CAAC,CAAC,CAAC,OAAO,CAAC,CACtC,CACF,CAAA;AACH,CAAC;AAED;;;;;;GAMG;AACH,MAAM,UAAU,6BAA6B,CAC3C,QAAmC,EACnC,MAAiC;IAEjC,IAAI,MAAM,KAAK,SAAS,EAAE,CAAC;QACzB,OAAO,SAAS,CAAA;IAClB,CAAC;IACD,IAAI,IAAyC,CAAA;IAC7C,KAAK,MAAM,OAAO,IAAI,QAAQ,EAAE,CAAC;QAC/B,MAAM,QAAQ,GAAG,iBAAiB,CAAC,OAAO,EAAE,MAAM,CAAC,CAAA;QACnD,IACE,QAAQ,CAAC,MAAM,GAAG,CAAC;YACnB,CAAC,CAAC,IAAI,IAAI,eAAe,CAAC,QAAQ,CAAC,GAAG,eAAe,CAAC,IAAI,CAAC,QAAQ,CAAC,CAAC,EACrE,CAAC;YACD,IAAI,GAAG,EAAE,GAAG,OAAO,EAAE,QAAQ,EAAE,CAAA;QACjC,CAAC;IACH,CAAC;IACD,OAAO,IAAI,CAAA;AACb,CAAC;AAED,MAAM,eAAe,GAAG,CAAC,CAAA;AACzB,MAAM,gBAAgB,GAAG,GAAG,CAAA;AAE5B;;;;;;;;;;;;;;;GAeG;AACH,MAAM,UAAU,sBAAsB,CACpC,QAAmC,EACnC,MAAiC,EACjC,MAAoC;IAEpC,MAAM,QAAQ,GAAG,IAAI,GAAG,EAAU,CAAA;IAClC,MAAM,WAAW,GAAG,MAAM;QACxB,CAAC,CAAC,QAAQ;aACL,GAAG,CAAC,CAAC,CAAC,EAAE,CAAC,iBAAiB,CAAC,CAAC,EAAE,MAAM,CAAC,CAAC;aACtC,MAAM,CAAC,QAAQ,CAAC,EAAE,CAAC,QAAQ,CAAC,MAAM,GAAG,CAAC,CAAC;QAC5C,CAAC,CAAC,EAAE,CAAA;IACN,IAAI,WAAW,CAAC,MAAM,GAAG,CAAC,EAAE,CAAC;QAC3B,OAAO,QAAQ,CAAA;IACjB,CAAC;IACD,MAAM,MAAM,GAAG,CAAC,QAAmC,EAAE,GAAW,EAAE,EAAE,CAClE,QAAQ,CAAC,IAAI,CAAC,CAAC,CAAC,EAAE,CAAC,GAAG,IAAI,CAAC,CAAC,WAAW,IAAI,GAAG,IAAI,CAAC,CAAC,SAAS,CAAC,CAAA;IAChE,MAAM,QAAQ,GAAG,WAAW,CAAC,GAAG,CAAC,QAAQ,CAAC,EAAE;QAC1C,IAAI,OAAO,GAAG,CAAC,CAAA;QACf,IAAI,SAAS,GAAG,CAAC,CAAA;QACjB,KAAK,MAAM,CAAC,GAAG,EAAE,IAAI,CAAC,IAAI,MAAM,EAAE,CAAC;YACjC,IAAI,MAAM,CAAC,QAAQ,EAAE,GAAG,CAAC,EAAE,CAAC;gBAC1B,OAAO,EAAE,CAAA;gBACT,SAAS,IAAI,IAAI,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAA;YAC3B,CAAC;QACH,CAAC;QACD,OAAO,SAAS,GAAG,CAAC,OAAO,GAAG,eAAe,CAAC,CAAA;IAChD,CAAC,CAAC,CAAA;IACF,MAAM,WAAW,GAAG,IAAI,CAAC,GAAG,CAAC,GAAG,QAAQ,CAAC,CAAA;IACzC,IAAI,WAAW,GAAG,gBAAgB,EAAE,CAAC;QACnC,OAAO,QAAQ,CAAA;IACjB,CAAC;IACD,MAAM,GAAG,GAAG,WAAW,CAAC,QAAQ,CAAC,OAAO,CAAC,WAAW,CAAC,CAAE,CAAA;IACvD,KAAK,MAAM,GAAG,IAAI,MAAM,CAAC,IAAI,EAAE,EAAE,CAAC;QAChC,IACE,CAAC,MAAM,CAAC,GAAG,EAAE,GAAG,CAAC;YACjB,WAAW,CAAC,IAAI,CAAC,QAAQ,CAAC,EAAE,CAAC,QAAQ,KAAK,GAAG,IAAI,MAAM,CAAC,QAAQ,EAAE,GAAG,CAAC,CAAC,EACvE,CAAC;YACD,QAAQ,CAAC,GAAG,CAAC,GAAG,CAAC,CAAA;QACnB,CAAC;IACH,CAAC;IACD,OAAO,QAAQ,CAAA;AACjB,CAAC;AAED,wEAAwE;AACxE,+EAA+E;AAC/E,SAAS,cAAc,CAAC,QAAmC;IACzD,MAAM,IAAI,GAAG,IAAI,GAAG,EAAU,CAAA;IAC9B,OAAO,QAAQ,CAAC,MAAM,CAAC,CAAC,CAAC,EAAE;QACzB,MAAM,GAAG,GAAG,GAAG,CAAC,CAAC,QAAQ,IAAI,CAAC,CAAC,MAAM,IAAI,CAAC,CAAC,WAAW,IAAI,CAAC,CAAC,SAAS,EAAE,CAAA;QACvE,MAAM,KAAK,GAAG,CAAC,IAAI,CAAC,GAAG,CAAC,GAAG,CAAC,CAAA;QAC5B,IAAI,CAAC,GAAG,CAAC,GAAG,CAAC,CAAA;QACb,OAAO,KAAK,CAAA;IACd,CAAC,CAAC,CAAA;AACJ,CAAC;AAED;mDACmD;AACnD,MAAM,CAAC,MAAM,0BAA0B,GAAuB,UAAU,CAAC,EAAE,CACzE,UAAU,GAAG,CAAC,CAAA;AAEhB,MAAM,UAAU,sBAAsB,CACpC,QAAmC;IAEnC,OAAO,UAAU,CAAC,EAAE;QAClB,MAAM,OAAO,GAAG,QAAQ,CAAC,IAAI,CAC3B,CAAC,CAAC,EAAE,CAAC,UAAU,IAAI,CAAC,CAAC,QAAQ,IAAI,UAAU,IAAI,CAAC,CAAC,MAAM,CACxD,CAAA;QACD,IAAI,CAAC,OAAO,EAAE,CAAC;YACb,OAAO,SAAS,CAAA;QAClB,CAAC;QACD,MAAM,GAAG,GAAG,OAAO,CAAC,WAAW,GAAG,CAAC,UAAU,GAAG,OAAO,CAAC,QAAQ,CAAC,CAAA;QACjE,OAAO,GAAG,IAAI,OAAO,CAAC,SAAS,CAAC,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,SAAS,CAAA;IACnD,CAAC,CAAA;AACH,CAAC"}
|
package/esm/structureFormat.d.ts
CHANGED
|
@@ -1,19 +1,14 @@
|
|
|
1
1
|
/**
|
|
2
2
|
* Which molstar trajectory parser a structure needs.
|
|
3
3
|
*
|
|
4
|
-
*
|
|
5
|
-
*
|
|
6
|
-
*
|
|
7
|
-
*
|
|
8
|
-
*
|
|
9
|
-
* error.
|
|
4
|
+
* A wrong choice fails either way. Parsing a PDB file as mmCIF throws
|
|
5
|
+
* ("Unexpected token. Expected data_, loop_, or data name"). Parsing an mmCIF
|
|
6
|
+
* as PDB succeeds and yields a model with zero polymer entities and thousands of
|
|
7
|
+
* misread atoms, so the structure loads with no sequence, no alignment and no
|
|
8
|
+
* genome mapping, and with no error.
|
|
10
9
|
*
|
|
11
|
-
*
|
|
12
|
-
*
|
|
13
|
-
*
|
|
14
|
-
* The two names are the subset of molstar's `BuiltInTrajectoryFormat` a
|
|
15
|
-
* structure loaded from a file or a url can be, spelled out rather than
|
|
16
|
-
* imported so nothing here depends on molstar.
|
|
10
|
+
* The two names are the subset of molstar's `BuiltInTrajectoryFormat` that a
|
|
11
|
+
* structure file or URL can be, written out so nothing here imports molstar.
|
|
17
12
|
*/
|
|
18
13
|
export type StructureFormat = 'pdb' | 'mmcif';
|
|
19
14
|
/** Trailing extension of a filename or URL, lowercased, ignoring any query or
|
|
@@ -21,18 +16,16 @@ export type StructureFormat = 'pdb' | 'mmcif';
|
|
|
21
16
|
export declare function structureFileExtension(nameOrUrl: string): string;
|
|
22
17
|
/**
|
|
23
18
|
* Format for a filename or URL. Unknown extensions fall back to mmCIF, which is
|
|
24
|
-
* what
|
|
25
|
-
* hand out `.cif`).
|
|
19
|
+
* what AlphaFold and RCSB serve (`.cif`).
|
|
26
20
|
*/
|
|
27
21
|
export declare function structureFormatFromName(nameOrUrl: string): StructureFormat;
|
|
28
22
|
/** Whether a URL points at a binary-encoded structure, which molstar must be
|
|
29
23
|
* told to download as bytes rather than text. */
|
|
30
24
|
export declare function isBinaryStructureUrl(url: string): boolean;
|
|
31
25
|
/**
|
|
32
|
-
* Format for structure text
|
|
33
|
-
*
|
|
34
|
-
*
|
|
35
|
-
* and is the only signal available here.
|
|
26
|
+
* Format for structure text with no filename, such as inline data, a pasted
|
|
27
|
+
* file, or a PDB built by `caCoordsToPdb`. The content is more reliable than a
|
|
28
|
+
* name, and here it is the only signal.
|
|
36
29
|
*
|
|
37
30
|
* mmCIF is line-oriented and its first meaningful line is a `data_` block
|
|
38
31
|
* header (comments and blank lines may precede it); PDB has none.
|
package/esm/structureFormat.js
CHANGED
|
@@ -14,8 +14,7 @@ export function structureFileExtension(nameOrUrl) {
|
|
|
14
14
|
}
|
|
15
15
|
/**
|
|
16
16
|
* Format for a filename or URL. Unknown extensions fall back to mmCIF, which is
|
|
17
|
-
* what
|
|
18
|
-
* hand out `.cif`).
|
|
17
|
+
* what AlphaFold and RCSB serve (`.cif`).
|
|
19
18
|
*/
|
|
20
19
|
export function structureFormatFromName(nameOrUrl) {
|
|
21
20
|
return PDB_EXTENSIONS.has(structureFileExtension(nameOrUrl)) ? 'pdb' : 'mmcif';
|
|
@@ -26,10 +25,9 @@ export function isBinaryStructureUrl(url) {
|
|
|
26
25
|
return structureFileExtension(url) === 'bcif';
|
|
27
26
|
}
|
|
28
27
|
/**
|
|
29
|
-
* Format for structure text
|
|
30
|
-
*
|
|
31
|
-
*
|
|
32
|
-
* and is the only signal available here.
|
|
28
|
+
* Format for structure text with no filename, such as inline data, a pasted
|
|
29
|
+
* file, or a PDB built by `caCoordsToPdb`. The content is more reliable than a
|
|
30
|
+
* name, and here it is the only signal.
|
|
33
31
|
*
|
|
34
32
|
* mmCIF is line-oriented and its first meaningful line is a `data_` block
|
|
35
33
|
* header (comments and blank lines may precede it); PDB has none.
|
|
@@ -1 +1 @@
|
|
|
1
|
-
{"version":3,"file":"structureFormat.js","sourceRoot":"","sources":["../src/structureFormat.ts"],"names":[],"mappings":"
|
|
1
|
+
{"version":3,"file":"structureFormat.js","sourceRoot":"","sources":["../src/structureFormat.ts"],"names":[],"mappings":"AAcA,gFAAgF;AAChF,wEAAwE;AACxE,MAAM,cAAc,GAAG,IAAI,GAAG,CAAC,CAAC,KAAK,EAAE,KAAK,EAAE,MAAM,EAAE,MAAM,EAAE,MAAM,CAAC,CAAC,CAAA;AAEtE;mEACmE;AACnE,MAAM,UAAU,sBAAsB,CAAC,SAAiB;IACtD,MAAM,IAAI,GAAG,SAAS,CAAC,KAAK,CAAC,MAAM,CAAC,CAAC,CAAC,CAAC,IAAI,EAAE,CAAA;IAC7C,MAAM,IAAI,GAAG,IAAI,CAAC,KAAK,CAAC,GAAG,CAAC,CAAC,GAAG,EAAE,IAAI,EAAE,CAAA;IACxC,MAAM,KAAK,GAAG,IAAI,CAAC,WAAW,EAAE,CAAC,KAAK,CAAC,GAAG,CAAC,CAAA;IAC3C,IAAI,KAAK,CAAC,EAAE,CAAC,CAAC,CAAC,CAAC,KAAK,IAAI,EAAE,CAAC;QAC1B,KAAK,CAAC,GAAG,EAAE,CAAA;IACb,CAAC;IACD,OAAO,KAAK,CAAC,MAAM,GAAG,CAAC,CAAC,CAAC,CAAC,CAAC,KAAK,CAAC,EAAE,CAAC,CAAC,CAAC,CAAC,IAAI,EAAE,CAAC,CAAC,CAAC,CAAC,EAAE,CAAA;AACrD,CAAC;AAED;;;GAGG;AACH,MAAM,UAAU,uBAAuB,CAAC,SAAiB;IACvD,OAAO,cAAc,CAAC,GAAG,CAAC,sBAAsB,CAAC,SAAS,CAAC,CAAC,CAAC,CAAC,CAAC,KAAK,CAAC,CAAC,CAAC,OAAO,CAAA;AAChF,CAAC;AAED;iDACiD;AACjD,MAAM,UAAU,oBAAoB,CAAC,GAAW;IAC9C,OAAO,sBAAsB,CAAC,GAAG,CAAC,KAAK,MAAM,CAAA;AAC/C,CAAC;AAED;;;;;;;GAOG;AACH,MAAM,UAAU,0BAA0B,CAAC,IAAY;IACrD,2EAA2E;IAC3E,wBAAwB;IACxB,KAAK,MAAM,IAAI,IAAI,IAAI,CAAC,KAAK,CAAC,CAAC,EAAE,IAAI,CAAC,CAAC,KAAK,CAAC,IAAI,CAAC,EAAE,CAAC;QACnD,MAAM,OAAO,GAAG,IAAI,CAAC,IAAI,EAAE,CAAA;QAC3B,IAAI,OAAO,KAAK,EAAE,IAAI,CAAC,OAAO,CAAC,UAAU,CAAC,GAAG,CAAC,EAAE,CAAC;YAC/C,OAAO,OAAO,CAAC,WAAW,EAAE,CAAC,UAAU,CAAC,OAAO,CAAC,CAAC,CAAC,CAAC,OAAO,CAAC,CAAC,CAAC,KAAK,CAAA;QACpE,CAAC;IACH,CAAC;IACD,OAAO,KAAK,CAAA;AACd,CAAC"}
|
|
@@ -11,7 +11,7 @@ export interface ExperimentalStructure {
|
|
|
11
11
|
end: number;
|
|
12
12
|
/** fraction of the UniProt sequence the entry covers, 0..1 */
|
|
13
13
|
coverage: number;
|
|
14
|
-
/** author chain ids
|
|
14
|
+
/** author chain ids of the protein */
|
|
15
15
|
chains: string[];
|
|
16
16
|
}
|
|
17
17
|
/** One polymer entity aligned to the accession. */
|
package/esm/structureUrls.d.ts
CHANGED
|
@@ -12,20 +12,15 @@ export declare function getPdbStructureUrl(pdbId: string): string;
|
|
|
12
12
|
export declare function isPdbId(value: string): boolean;
|
|
13
13
|
export declare function rcsbEntryUrl(pdbId: string): string;
|
|
14
14
|
/**
|
|
15
|
-
* Resolve the `{ pdbId }` shorthand to a
|
|
16
|
-
*
|
|
17
|
-
*
|
|
18
|
-
*
|
|
15
|
+
* Resolve the `{ pdbId }` shorthand to a structure URL, so a hand-written config
|
|
16
|
+
* or a short launch URL needs no RCSB filename. An explicit `url` (or inline
|
|
17
|
+
* `data`) always wins, and resolving an already-resolved spec returns the same
|
|
18
|
+
* url.
|
|
19
19
|
*
|
|
20
|
-
* `uniprotId`
|
|
21
|
-
*
|
|
22
|
-
*
|
|
23
|
-
*
|
|
24
|
-
* file to open.
|
|
25
|
-
*
|
|
26
|
-
* Shared by the Structure model's snapshot preprocessor and the
|
|
27
|
-
* LaunchView-ProteinView extension point, which would otherwise each carry
|
|
28
|
-
* their own copy of the same precedence rule.
|
|
20
|
+
* `uniprotId` resolves to no url and still outranks a `pdbId`. AlphaFold DB's
|
|
21
|
+
* files for an accession change (an isoform model, several fragments, a new
|
|
22
|
+
* model version), so the caller keeps the accession and asks
|
|
23
|
+
* `fetchAlphaFoldModels` which file to open.
|
|
29
24
|
*/
|
|
30
25
|
export declare function resolveStructureUrl({ url, data, uniprotId, pdbId, }: {
|
|
31
26
|
url?: string;
|
|
@@ -45,9 +40,9 @@ export declare function getUniprotIdFromAlphaFoldTarget(target: string): string
|
|
|
45
40
|
export declare function getStructureUrlFromTarget(target: string, db: string): string | undefined;
|
|
46
41
|
export declare function getConfidenceUrlFromTarget(target: string): string | undefined;
|
|
47
42
|
/**
|
|
48
|
-
*
|
|
49
|
-
*
|
|
50
|
-
*
|
|
43
|
+
* The name to show for a structure: its PDB id, its AlphaFold accession, else
|
|
44
|
+
* the file's name. Use it wherever a structure is named, so each place shows
|
|
45
|
+
* the same name.
|
|
51
46
|
*/
|
|
52
47
|
export declare function structureDisplayLabel({ url, data, uniprotId, }: {
|
|
53
48
|
url?: string;
|
package/esm/structureUrls.js
CHANGED
|
@@ -1,11 +1,7 @@
|
|
|
1
|
-
//
|
|
2
|
-
// the launch flow and the ProteinView model (e.g. resolving a `uniprotId`/`pdbId`
|
|
3
|
-
// shorthand at hydration) can import them without pulling in heavy launch code.
|
|
1
|
+
// Structure URL builders and target parsers, with no dependencies.
|
|
4
2
|
const ALPHAFOLD_VERSION = 'v6';
|
|
5
|
-
// UniProt endpoints. rest.* is the machine API
|
|
6
|
-
// the
|
|
7
|
-
// assembly is built from); www.*/entry is the human-facing entry page the UI
|
|
8
|
-
// links to. Centralized so a path change is one edit rather than a grep.
|
|
3
|
+
// UniProt endpoints. rest.* is the machine API, serving the features as GFF
|
|
4
|
+
// and the sequence as FASTA; www.*/entry is the entry page for people.
|
|
9
5
|
export function uniprotGffUrl(uniprotId) {
|
|
10
6
|
return `https://rest.uniprot.org/uniprotkb/${uniprotId}.gff`;
|
|
11
7
|
}
|
|
@@ -37,20 +33,15 @@ export function rcsbEntryUrl(pdbId) {
|
|
|
37
33
|
return `https://www.rcsb.org/structure/${pdbId.toUpperCase()}`;
|
|
38
34
|
}
|
|
39
35
|
/**
|
|
40
|
-
* Resolve the `{ pdbId }` shorthand to a
|
|
41
|
-
*
|
|
42
|
-
*
|
|
43
|
-
*
|
|
36
|
+
* Resolve the `{ pdbId }` shorthand to a structure URL, so a hand-written config
|
|
37
|
+
* or a short launch URL needs no RCSB filename. An explicit `url` (or inline
|
|
38
|
+
* `data`) always wins, and resolving an already-resolved spec returns the same
|
|
39
|
+
* url.
|
|
44
40
|
*
|
|
45
|
-
* `uniprotId`
|
|
46
|
-
*
|
|
47
|
-
*
|
|
48
|
-
*
|
|
49
|
-
* file to open.
|
|
50
|
-
*
|
|
51
|
-
* Shared by the Structure model's snapshot preprocessor and the
|
|
52
|
-
* LaunchView-ProteinView extension point, which would otherwise each carry
|
|
53
|
-
* their own copy of the same precedence rule.
|
|
41
|
+
* `uniprotId` resolves to no url and still outranks a `pdbId`. AlphaFold DB's
|
|
42
|
+
* files for an accession change (an isoform model, several fragments, a new
|
|
43
|
+
* model version), so the caller keeps the accession and asks
|
|
44
|
+
* `fetchAlphaFoldModels` which file to open.
|
|
54
45
|
*/
|
|
55
46
|
export function resolveStructureUrl({ url, data, uniprotId, pdbId, }) {
|
|
56
47
|
if (url !== undefined || data !== undefined) {
|
|
@@ -117,9 +108,9 @@ export function getConfidenceUrlFromTarget(target) {
|
|
|
117
108
|
return undefined;
|
|
118
109
|
}
|
|
119
110
|
/**
|
|
120
|
-
*
|
|
121
|
-
*
|
|
122
|
-
*
|
|
111
|
+
* The name to show for a structure: its PDB id, its AlphaFold accession, else
|
|
112
|
+
* the file's name. Use it wherever a structure is named, so each place shows
|
|
113
|
+
* the same name.
|
|
123
114
|
*/
|
|
124
115
|
export function structureDisplayLabel({ url, data, uniprotId, }) {
|
|
125
116
|
if (url === undefined) {
|
package/esm/structureUrls.js.map
CHANGED
|
@@ -1 +1 @@
|
|
|
1
|
-
{"version":3,"file":"structureUrls.js","sourceRoot":"","sources":["../src/structureUrls.ts"],"names":[],"mappings":"AAAA
|
|
1
|
+
{"version":3,"file":"structureUrls.js","sourceRoot":"","sources":["../src/structureUrls.ts"],"names":[],"mappings":"AAAA,mEAAmE;AAEnE,MAAM,iBAAiB,GAAG,IAAI,CAAA;AAE9B,4EAA4E;AAC5E,uEAAuE;AACvE,MAAM,UAAU,aAAa,CAAC,SAAiB;IAC7C,OAAO,sCAAsC,SAAS,MAAM,CAAA;AAC9D,CAAC;AAED,MAAM,UAAU,eAAe,CAAC,SAAiB;IAC/C,OAAO,sCAAsC,SAAS,QAAQ,CAAA;AAChE,CAAC;AAED,MAAM,UAAU,eAAe,CAAC,SAAiB;IAC/C,OAAO,qCAAqC,SAAS,QAAQ,CAAA;AAC/D,CAAC;AAED;;;;;GAKG;AACH,MAAM,UAAU,wBAAwB,CACtC,SAAiB,EACjB,OAAO,GAAG,iBAAiB;IAE3B,OAAO,wCAAwC,SAAS,aAAa,OAAO,MAAM,CAAA;AACpF,CAAC;AAED,MAAM,UAAU,kBAAkB,CAAC,KAAa;IAC9C,OAAO,mCAAmC,KAAK,MAAM,CAAA;AACvD,CAAC;AAED,6EAA6E;AAC7E,8EAA8E;AAC9E,gBAAgB;AAChB,MAAM,UAAU,OAAO,CAAC,KAAa;IACnC,OAAO,uBAAuB,CAAC,IAAI,CAAC,KAAK,CAAC,CAAA;AAC5C,CAAC;AAED,MAAM,UAAU,YAAY,CAAC,KAAa;IACxC,OAAO,kCAAkC,KAAK,CAAC,WAAW,EAAE,EAAE,CAAA;AAChE,CAAC;AAED;;;;;;;;;;GAUG;AACH,MAAM,UAAU,mBAAmB,CAAC,EAClC,GAAG,EACH,IAAI,EACJ,SAAS,EACT,KAAK,GAMN;IACC,IAAI,GAAG,KAAK,SAAS,IAAI,IAAI,KAAK,SAAS,EAAE,CAAC;QAC5C,OAAO,GAAG,CAAA;IACZ,CAAC;IACD,OAAO,SAAS,KAAK,SAAS,IAAI,KAAK,KAAK,SAAS;QACnD,CAAC,CAAC,SAAS;QACX,CAAC,CAAC,kBAAkB,CAAC,KAAK,CAAC,CAAA;AAC/B,CAAC;AAED,8EAA8E;AAC9E,iFAAiF;AACjF,8DAA8D;AAC9D,MAAM,iBAAiB,GAAG,CAAC,gBAAgB,EAAE,eAAe,EAAE,eAAe,CAAC,CAAA;AAE9E;;;;GAIG;AACH,MAAM,UAAU,eAAe,CAAC,GAAW;IACzC,MAAM,EAAE,IAAI,EAAE,IAAI,EAAE,GAAG,CAAC,GAAG,EAAE;QAC3B,IAAI,CAAC;YACH,MAAM,MAAM,GAAG,IAAI,GAAG,CAAC,GAAG,CAAC,CAAA;YAC3B,OAAO,EAAE,IAAI,EAAE,MAAM,CAAC,QAAQ,EAAE,IAAI,EAAE,MAAM,CAAC,QAAQ,CAAC,KAAK,CAAC,GAAG,CAAC,CAAC,GAAG,EAAE,EAAE,CAAA;QAC1E,CAAC;QAAC,MAAM,CAAC;YACP,OAAO,EAAE,IAAI,EAAE,SAAS,EAAE,IAAI,EAAE,SAAS,EAAE,CAAA;QAC7C,CAAC;IACH,CAAC,CAAC,EAAE,CAAA;IACJ,IAAI,IAAI,KAAK,SAAS,IAAI,CAAC,iBAAiB,CAAC,QAAQ,CAAC,IAAI,CAAC,EAAE,CAAC;QAC5D,OAAO,SAAS,CAAA;IAClB,CAAC;IACD,MAAM,KAAK,GACT,2EAA2E,CAAC,IAAI,CAC9E,IAAI,IAAI,EAAE,CACX,CAAA;IACH,OAAO,KAAK,EAAE,CAAC,CAAC,CAAC,EAAE,WAAW,EAAE,CAAA;AAClC,CAAC;AAED,yEAAyE;AACzE,yEAAyE;AACzE,SAAS,eAAe,CAAC,MAAc;IACrC,OAAO,MAAM,CAAC,KAAK,CAAC,GAAG,CAAC,CAAC,CAAC,CAAE,CAAA;AAC9B,CAAC;AAED;+EAC+E;AAC/E,MAAM,UAAU,+BAA+B,CAAC,MAAc;IAC5D,MAAM,KAAK,GAAG,8BAA8B,CAAC,IAAI,CAAC,eAAe,CAAC,MAAM,CAAC,CAAC,CAAA;IAC1E,OAAO,KAAK,EAAE,CAAC,CAAC,CAAC,CAAA;AACnB,CAAC;AAED,0EAA0E;AAC1E,wEAAwE;AACxE,MAAM,UAAU,yBAAyB,CAAC,MAAc,EAAE,EAAU;IAClE,MAAM,QAAQ,GAAG,eAAe,CAAC,MAAM,CAAC,CAAA;IACxC,IAAI,QAAQ,CAAC,UAAU,CAAC,KAAK,CAAC,EAAE,CAAC;QAC/B,OAAO,qCAAqC,QAAQ,MAAM,CAAA;IAC5D,CAAC;IACD,MAAM,KAAK,GACT,EAAE,KAAK,QAAQ;QACb,CAAC,CAAC,iCAAiC,CAAC,IAAI,CAAC,QAAQ,CAAC,EAAE,CAAC,CAAC,CAAC;QACvD,CAAC,CAAC,SAAS,CAAA;IACf,OAAO,KAAK,CAAC,CAAC,CAAC,kBAAkB,CAAC,KAAK,CAAC,CAAC,CAAC,CAAC,SAAS,CAAA;AACtD,CAAC;AAED,MAAM,UAAU,0BAA0B,CAAC,MAAc;IACvD,MAAM,QAAQ,GAAG,eAAe,CAAC,MAAM,CAAC,CAAA;IACxC,IAAI,QAAQ,CAAC,UAAU,CAAC,KAAK,CAAC,EAAE,CAAC;QAC/B,MAAM,YAAY,GAAG,QAAQ,CAAC,OAAO,CAAC,SAAS,EAAE,cAAc,CAAC,CAAA;QAChE,OAAO,qCAAqC,YAAY,OAAO,CAAA;IACjE,CAAC;IACD,OAAO,SAAS,CAAA;AAClB,CAAC;AAED;;;;GAIG;AACH,MAAM,UAAU,qBAAqB,CAAC,EACpC,GAAG,EACH,IAAI,EACJ,SAAS,GAKV;IACC,IAAI,GAAG,KAAK,SAAS,EAAE,CAAC;QACtB,OAAO,IAAI,KAAK,SAAS;YACvB,CAAC,CAAC,oBAAoB;YACtB,CAAC,CAAC,SAAS;gBACT,CAAC,CAAC,aAAa,SAAS,EAAE;gBAC1B,CAAC,CAAC,EAAE,CAAA;IACV,CAAC;IACD,MAAM,KAAK,GAAG,eAAe,CAAC,GAAG,CAAC,CAAA;IAClC,IAAI,KAAK,EAAE,CAAC;QACV,OAAO,KAAK,CAAC,WAAW,EAAE,CAAA;IAC5B,CAAC;IACD,MAAM,YAAY,GAAG,+BAA+B,CAAC,GAAG,CAAC,CAAA;IACzD,IAAI,YAAY,EAAE,CAAC;QACjB,OAAO,aAAa,YAAY,EAAE,CAAA;IACpC,CAAC;IACD,MAAM,IAAI,GAAG,GAAG,CAAC,KAAK,CAAC,GAAG,CAAC,CAAC,GAAG,EAAE,EAAE,KAAK,CAAC,GAAG,CAAC,CAAC,CAAC,CAAC,CAAA;IAChD,OAAO,IAAI,KAAK,SAAS,IAAI,IAAI,KAAK,EAAE,CAAC,CAAC,CAAC,GAAG,CAAC,CAAC,CAAC,IAAI,CAAA;AACvD,CAAC"}
|
package/esm/types.d.ts
CHANGED
|
@@ -5,10 +5,7 @@ export declare const ALIGNMENT_ALGORITHMS: {
|
|
|
5
5
|
};
|
|
6
6
|
export declare const DEFAULT_ALIGNMENT_ALGORITHM: AlignmentAlgorithm;
|
|
7
7
|
export declare const ALIGNMENT_ALGORITHM_VALUES: AlignmentAlgorithm[];
|
|
8
|
-
/**
|
|
9
|
-
*
|
|
10
|
-
* The only place a coercion is needed: the model property is an enumeration, so
|
|
11
|
-
* everything downstream of hydration is already typed.
|
|
12
|
-
*/
|
|
8
|
+
/** Parses an untrusted algorithm name, such as a URL parameter, falling back
|
|
9
|
+
* to Smith-Waterman. */
|
|
13
10
|
export declare function coerceAlignmentAlgorithm(value: string): AlignmentAlgorithm;
|
|
14
11
|
export declare const ALIGNMENT_ALGORITHM_LABELS: Record<AlignmentAlgorithm, string>;
|
package/esm/types.js
CHANGED
|
@@ -7,11 +7,8 @@ export const ALIGNMENT_ALGORITHM_VALUES = [
|
|
|
7
7
|
'needleman_wunsch',
|
|
8
8
|
'smith_waterman',
|
|
9
9
|
];
|
|
10
|
-
/**
|
|
11
|
-
*
|
|
12
|
-
* The only place a coercion is needed: the model property is an enumeration, so
|
|
13
|
-
* everything downstream of hydration is already typed.
|
|
14
|
-
*/
|
|
10
|
+
/** Parses an untrusted algorithm name, such as a URL parameter, falling back
|
|
11
|
+
* to Smith-Waterman. */
|
|
15
12
|
export function coerceAlignmentAlgorithm(value) {
|
|
16
13
|
return (ALIGNMENT_ALGORITHM_VALUES.find(v => v === value) ??
|
|
17
14
|
DEFAULT_ALIGNMENT_ALGORITHM);
|
package/esm/types.js.map
CHANGED
|
@@ -1 +1 @@
|
|
|
1
|
-
{"version":3,"file":"types.js","sourceRoot":"","sources":["../src/types.ts"],"names":[],"mappings":"AAEA,MAAM,CAAC,MAAM,oBAAoB,GAAG;IAClC,gBAAgB,EAAE,kBAAkB;IACpC,cAAc,EAAE,gBAAgB;CACxB,CAAA;AAEV,MAAM,CAAC,MAAM,2BAA2B,GAAuB,gBAAgB,CAAA;AAE/E,MAAM,CAAC,MAAM,0BAA0B,GAAyB;IAC9D,kBAAkB;IAClB,gBAAgB;CACjB,CAAA;AAED
|
|
1
|
+
{"version":3,"file":"types.js","sourceRoot":"","sources":["../src/types.ts"],"names":[],"mappings":"AAEA,MAAM,CAAC,MAAM,oBAAoB,GAAG;IAClC,gBAAgB,EAAE,kBAAkB;IACpC,cAAc,EAAE,gBAAgB;CACxB,CAAA;AAEV,MAAM,CAAC,MAAM,2BAA2B,GAAuB,gBAAgB,CAAA;AAE/E,MAAM,CAAC,MAAM,0BAA0B,GAAyB;IAC9D,kBAAkB;IAClB,gBAAgB;CACjB,CAAA;AAED;wBACwB;AACxB,MAAM,UAAU,wBAAwB,CAAC,KAAa;IACpD,OAAO,CACL,0BAA0B,CAAC,IAAI,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,KAAK,KAAK,CAAC;QACjD,2BAA2B,CAC5B,CAAA;AACH,CAAC;AAED,MAAM,CAAC,MAAM,0BAA0B,GAAuC;IAC5E,gBAAgB,EAAE,kBAAkB;IACpC,cAAc,EAAE,gBAAgB;CACjC,CAAA"}
|
package/esm/uniProtSearch.js
CHANGED
|
@@ -47,7 +47,6 @@ async function searchByXref(id, opts) {
|
|
|
47
47
|
return { entries: await searchUniProt(query, 10, opts), error: undefined };
|
|
48
48
|
}
|
|
49
49
|
catch (e) {
|
|
50
|
-
console.error(`xref search failed for ${id}:`, e);
|
|
51
50
|
return { entries: [], error: e };
|
|
52
51
|
}
|
|
53
52
|
}
|
|
@@ -59,18 +58,14 @@ async function searchByGeneName(geneName, organismId, opts) {
|
|
|
59
58
|
// are 284812. The descendants are asked only on a miss, because for a
|
|
60
59
|
// species with reviewed subspecies entries (human and Neanderthal) they
|
|
61
60
|
// turn one answer into two.
|
|
62
|
-
//
|
|
63
|
-
//
|
|
61
|
+
// When the descendant search fails, the taxon's own empty result stands
|
|
62
|
+
// rather than becoming an error.
|
|
64
63
|
const entries = exact.length === 0 && organismId
|
|
65
|
-
? await searchUniProt(buildGeneNameQuery(geneName, organismId, 'taxonomy_id'), 5, opts).catch((
|
|
66
|
-
console.error(`descendant-taxon search failed for ${geneName}:`, e);
|
|
67
|
-
return exact;
|
|
68
|
-
})
|
|
64
|
+
? await searchUniProt(buildGeneNameQuery(geneName, organismId, 'taxonomy_id'), 5, opts).catch(() => exact)
|
|
69
65
|
: exact;
|
|
70
66
|
return { entries, error: undefined };
|
|
71
67
|
}
|
|
72
68
|
catch (e) {
|
|
73
|
-
console.error(`gene name search failed for ${geneName}:`, e);
|
|
74
69
|
return { entries: [], error: e };
|
|
75
70
|
}
|
|
76
71
|
}
|
package/esm/uniProtSearch.js.map
CHANGED
|
@@ -1 +1 @@
|
|
|
1
|
-
{"version":3,"file":"uniProtSearch.js","sourceRoot":"","sources":["../src/uniProtSearch.ts"],"names":[],"mappings":"AAAA,OAAO,EAAE,SAAS,EAAE,MAAM,iBAAiB,CAAA;AAC3C,OAAO,EACL,qBAAqB,EACrB,sBAAsB,EACtB,oBAAoB,GACrB,MAAM,YAAY,CAAA;AAsCnB,MAAM,cAAc,GAClB,6DAA6D,CAAA;AAE/D,SAAS,mBAAmB,CAC1B,MAAsC;IAEtC,OAAO;QACL,SAAS,EAAE,MAAM,CAAC,gBAAgB;QAClC,EAAE,EAAE,MAAM,CAAC,WAAW;QACtB,QAAQ,EAAE,MAAM,CAAC,KAAK,EAAE,CAAC,CAAC,CAAC,EAAE,QAAQ,EAAE,KAAK;QAC5C,YAAY,EACV,MAAM,CAAC,QAAQ,EAAE,UAAU,IAAI,MAAM,CAAC,QAAQ,EAAE,cAAc;QAChE,WAAW,EAAE,MAAM,CAAC,kBAAkB,EAAE,eAAe,EAAE,QAAQ,EAAE,KAAK;QACxE,UAAU,EAAE,MAAM,CAAC,SAAS,KAAK,iCAAiC;KACnE,CAAA;AACH,CAAC;AAED,KAAK,UAAU,aAAa,CAC1B,KAAa,EACb,IAAY,EACZ,IAAmB;IAEnB,MAAM,GAAG,GAAG,mDAAmD,kBAAkB,CAAC,KAAK,CAAC,WAAW,cAAc,SAAS,IAAI,EAAE,CAAA;IAChI,MAAM,IAAI,GAAG,MAAM,SAAS,CAAmB,GAAG,EAAE,IAAI,CAAC,CAAA;IACzD,OAAO,IAAI,CAAC,OAAO,CAAC,GAAG,CAAC,mBAAmB,CAAC,CAAA;AAC9C,CAAC;AAED;;;;;;;;;;;;GAYG;AACH,MAAM,UAAU,kBAAkB,CAChC,QAAgB,EAChB,UAAmB,EACnB,QAAuC,aAAa;IAEpD,OAAO;QACL,eAAe,QAAQ,CAAC,UAAU,CAAC,GAAG,EAAE,KAAK,CAAC,GAAG;QACjD,UAAU,CAAC,CAAC,CAAC,GAAG,KAAK,IAAI,UAAU,EAAE,CAAC,CAAC,CAAC,SAAS;QACjD,eAAe;KAChB;SACE,MAAM,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,KAAK,SAAS,CAAC;SAC5B,IAAI,CAAC,OAAO,CAAC,CAAA;AAClB,CAAC;AAOD,KAAK,UAAU,YAAY,CACzB,EAAU,EACV,IAAmB;IAEnB,MAAM,KAAK,GAAG,qBAAqB,CAAC,EAAE,CAAC,CAAA;IACvC,IAAI,CAAC,KAAK,EAAE,CAAC;QACX,OAAO,EAAE,OAAO,EAAE,EAAE,EAAE,KAAK,EAAE,SAAS,EAAE,CAAA;IAC1C,CAAC;IACD,IAAI,CAAC;QACH,OAAO,EAAE,OAAO,EAAE,MAAM,aAAa,CAAC,KAAK,EAAE,EAAE,EAAE,IAAI,CAAC,EAAE,KAAK,EAAE,SAAS,EAAE,CAAA;IAC5E,CAAC;IAAC,OAAO,CAAC,EAAE,CAAC;QACX,OAAO,
|
|
1
|
+
{"version":3,"file":"uniProtSearch.js","sourceRoot":"","sources":["../src/uniProtSearch.ts"],"names":[],"mappings":"AAAA,OAAO,EAAE,SAAS,EAAE,MAAM,iBAAiB,CAAA;AAC3C,OAAO,EACL,qBAAqB,EACrB,sBAAsB,EACtB,oBAAoB,GACrB,MAAM,YAAY,CAAA;AAsCnB,MAAM,cAAc,GAClB,6DAA6D,CAAA;AAE/D,SAAS,mBAAmB,CAC1B,MAAsC;IAEtC,OAAO;QACL,SAAS,EAAE,MAAM,CAAC,gBAAgB;QAClC,EAAE,EAAE,MAAM,CAAC,WAAW;QACtB,QAAQ,EAAE,MAAM,CAAC,KAAK,EAAE,CAAC,CAAC,CAAC,EAAE,QAAQ,EAAE,KAAK;QAC5C,YAAY,EACV,MAAM,CAAC,QAAQ,EAAE,UAAU,IAAI,MAAM,CAAC,QAAQ,EAAE,cAAc;QAChE,WAAW,EAAE,MAAM,CAAC,kBAAkB,EAAE,eAAe,EAAE,QAAQ,EAAE,KAAK;QACxE,UAAU,EAAE,MAAM,CAAC,SAAS,KAAK,iCAAiC;KACnE,CAAA;AACH,CAAC;AAED,KAAK,UAAU,aAAa,CAC1B,KAAa,EACb,IAAY,EACZ,IAAmB;IAEnB,MAAM,GAAG,GAAG,mDAAmD,kBAAkB,CAAC,KAAK,CAAC,WAAW,cAAc,SAAS,IAAI,EAAE,CAAA;IAChI,MAAM,IAAI,GAAG,MAAM,SAAS,CAAmB,GAAG,EAAE,IAAI,CAAC,CAAA;IACzD,OAAO,IAAI,CAAC,OAAO,CAAC,GAAG,CAAC,mBAAmB,CAAC,CAAA;AAC9C,CAAC;AAED;;;;;;;;;;;;GAYG;AACH,MAAM,UAAU,kBAAkB,CAChC,QAAgB,EAChB,UAAmB,EACnB,QAAuC,aAAa;IAEpD,OAAO;QACL,eAAe,QAAQ,CAAC,UAAU,CAAC,GAAG,EAAE,KAAK,CAAC,GAAG;QACjD,UAAU,CAAC,CAAC,CAAC,GAAG,KAAK,IAAI,UAAU,EAAE,CAAC,CAAC,CAAC,SAAS;QACjD,eAAe;KAChB;SACE,MAAM,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,KAAK,SAAS,CAAC;SAC5B,IAAI,CAAC,OAAO,CAAC,CAAA;AAClB,CAAC;AAOD,KAAK,UAAU,YAAY,CACzB,EAAU,EACV,IAAmB;IAEnB,MAAM,KAAK,GAAG,qBAAqB,CAAC,EAAE,CAAC,CAAA;IACvC,IAAI,CAAC,KAAK,EAAE,CAAC;QACX,OAAO,EAAE,OAAO,EAAE,EAAE,EAAE,KAAK,EAAE,SAAS,EAAE,CAAA;IAC1C,CAAC;IACD,IAAI,CAAC;QACH,OAAO,EAAE,OAAO,EAAE,MAAM,aAAa,CAAC,KAAK,EAAE,EAAE,EAAE,IAAI,CAAC,EAAE,KAAK,EAAE,SAAS,EAAE,CAAA;IAC5E,CAAC;IAAC,OAAO,CAAC,EAAE,CAAC;QACX,OAAO,EAAE,OAAO,EAAE,EAAE,EAAE,KAAK,EAAE,CAAC,EAAE,CAAA;IAClC,CAAC;AACH,CAAC;AAED,KAAK,UAAU,gBAAgB,CAC7B,QAAgB,EAChB,UAA8B,EAC9B,IAAmB;IAEnB,IAAI,CAAC;QACH,MAAM,KAAK,GAAG,MAAM,aAAa,CAC/B,kBAAkB,CAAC,QAAQ,EAAE,UAAU,CAAC,EACxC,UAAU,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,EAAE,EACnB,IAAI,CACL,CAAA;QACD,0EAA0E;QAC1E,0EAA0E;QAC1E,sEAAsE;QACtE,wEAAwE;QACxE,4BAA4B;QAC5B,wEAAwE;QACxE,iCAAiC;QACjC,MAAM,OAAO,GACX,KAAK,CAAC,MAAM,KAAK,CAAC,IAAI,UAAU;YAC9B,CAAC,CAAC,MAAM,aAAa,CACjB,kBAAkB,CAAC,QAAQ,EAAE,UAAU,EAAE,aAAa,CAAC,EACvD,CAAC,EACD,IAAI,CACL,CAAC,KAAK,CAAC,GAAG,EAAE,CAAC,KAAK,CAAC;YACtB,CAAC,CAAC,KAAK,CAAA;QACX,OAAO,EAAE,OAAO,EAAE,KAAK,EAAE,SAAS,EAAE,CAAA;IACtC,CAAC;IAAC,OAAO,CAAC,EAAE,CAAC;QACX,OAAO,EAAE,OAAO,EAAE,EAAE,EAAE,KAAK,EAAE,CAAC,EAAE,CAAA;IAClC,CAAC;AACH,CAAC;AAED,SAAS,kBAAkB,CAAC,OAAuB;IACjD,MAAM,IAAI,GAAG,IAAI,GAAG,EAAU,CAAA;IAC9B,MAAM,MAAM,GAAmB,EAAE,CAAA;IACjC,KAAK,MAAM,KAAK,IAAI,OAAO,EAAE,CAAC;QAC5B,IAAI,CAAC,IAAI,CAAC,GAAG,CAAC,KAAK,CAAC,SAAS,CAAC,EAAE,CAAC;YAC/B,IAAI,CAAC,GAAG,CAAC,KAAK,CAAC,SAAS,CAAC,CAAA;YACzB,MAAM,CAAC,IAAI,CAAC,KAAK,CAAC,CAAA;QACpB,CAAC;IACH,CAAC;IACD,OAAO,MAAM,CAAA;AACf,CAAC;AAQD,MAAM,CAAC,KAAK,UAAU,oBAAoB,CACxC,EACE,aAAa,GAAG,EAAE,EAClB,MAAM,EACN,QAAQ,EACR,UAAU,GAOX,EACD,IAAmB;IAEnB,MAAM,WAAW,GAAG,IAAI,GAAG,CAAC,aAAa,CAAC,CAAA;IAC1C,MAAM,cAAc,GAAG,MAAM,CAAC,CAAC,CAAC,oBAAoB,CAAC,MAAM,CAAC,CAAC,CAAC,CAAC,SAAS,CAAA;IACxE,IAAI,cAAc,IAAI,sBAAsB,CAAC,cAAc,CAAC,EAAE,CAAC;QAC7D,WAAW,CAAC,GAAG,CAAC,cAAc,CAAC,CAAA;IACjC,CAAC;IAED,6EAA6E;IAC7E,2EAA2E;IAC3E,uEAAuE;IACvE,MAAM,CAAC,WAAW,EAAE,UAAU,CAAC,GAAG,MAAM,OAAO,CAAC,GAAG,CAAC;QAClD,OAAO,CAAC,GAAG,CAAC,CAAC,GAAG,WAAW,CAAC,CAAC,GAAG,CAAC,EAAE,CAAC,EAAE,CAAC,YAAY,CAAC,EAAE,EAAE,IAAI,CAAC,CAAC,CAAC;QAC/D,QAAQ,CAAC,CAAC,CAAC,gBAAgB,CAAC,QAAQ,EAAE,UAAU,EAAE,IAAI,CAAC,CAAC,CAAC,CAAC,SAAS;KACpE,CAAC,CAAA;IAEF,IAAI,OAAO,GAAG,kBAAkB,CAAC,WAAW,CAAC,OAAO,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,OAAO,CAAC,CAAC,CAAA;IACrE,wEAAwE;IACxE,6EAA6E;IAC7E,yEAAyE;IACzE,MAAM,mBAAmB,GACvB,UAAU,IAAI,CAAC,OAAO,CAAC,IAAI,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,UAAU,CAAC,CAAC,CAAC,CAAC,UAAU,CAAC,CAAC,CAAC,SAAS,CAAA;IACzE,IAAI,mBAAmB,EAAE,CAAC;QACxB,OAAO,GAAG,kBAAkB,CAAC,CAAC,GAAG,OAAO,EAAE,GAAG,mBAAmB,CAAC,OAAO,CAAC,CAAC,CAAA;IAC5E,CAAC;IAED,MAAM,cAAc,GAAG,WAAW,CAAC,IAAI,GAAG,CAAC,mBAAmB,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAA;IACvE,MAAM,WAAW,GACf,WAAW,CAAC,MAAM,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,KAAK,KAAK,SAAS,CAAC,CAAC,MAAM;QACrD,CAAC,mBAAmB,EAAE,KAAK,KAAK,SAAS,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAC,CAAA;IAEpD,4EAA4E;IAC5E,6EAA6E;IAC7E,IACE,OAAO,CAAC,MAAM,KAAK,CAAC;QACpB,cAAc,GAAG,CAAC;QAClB,cAAc,KAAK,WAAW,EAC9B,CAAC;QACD,MAAM,CACJ,mBAAmB,EAAE,KAAK;YAC1B,WAAW,CAAC,IAAI,CAAC,CAAC,CAAC,EAAE,CAAC,CAAC,CAAC,KAAK,KAAK,SAAS,CAAC,EAAE,KAAK,CACpD,CAAA;IACH,CAAC;IAED,OAAO;QACL,OAAO,EAAE,OAAO,CAAC,QAAQ,CACvB,CAAC,CAAC,EAAE,CAAC,EAAE,EAAE,CAAC,MAAM,CAAC,CAAC,CAAC,UAAU,CAAC,GAAG,MAAM,CAAC,CAAC,CAAC,UAAU,CAAC,CACtD;QACD,cAAc;QACd,WAAW;KACZ,CAAA;AACH,CAAC"}
|
package/package.json
CHANGED
|
@@ -1,7 +1,7 @@
|
|
|
1
1
|
{
|
|
2
2
|
"name": "p2s_mapper",
|
|
3
3
|
"description": "Map a transcript's translation onto a protein structure: alignment, coordinates, chain choice, UniProt mapping, and the AlphaFold and RCSB lookups that find the structure",
|
|
4
|
-
"version": "2.
|
|
4
|
+
"version": "2.1.0",
|
|
5
5
|
"packageManager": "pnpm@11.15.1",
|
|
6
6
|
"repository": {
|
|
7
7
|
"type": "git",
|
package/src/alignmentQuality.ts
CHANGED
|
@@ -7,21 +7,21 @@ import {
|
|
|
7
7
|
import type { PairwiseAlignment } from './mappings.ts'
|
|
8
8
|
|
|
9
9
|
export interface AlignmentQuality {
|
|
10
|
-
/** columns
|
|
10
|
+
/** columns with a residue in both rows, i.e. mapped positions */
|
|
11
11
|
aligned: number
|
|
12
12
|
identical: number
|
|
13
13
|
transcriptLength: number
|
|
14
14
|
structureLength: number
|
|
15
15
|
/** identical over aligned; 0 when nothing aligned */
|
|
16
16
|
identity: number
|
|
17
|
-
/** identical over the shorter of the two sequences
|
|
18
|
-
*
|
|
17
|
+
/** identical over the shorter of the two sequences, which separates a
|
|
18
|
+
* real match from a chance local alignment (see LOW_IDENTITY_OVER_SHORTER) */
|
|
19
19
|
identityOverShorter: number
|
|
20
20
|
/** aligned over the structure's length */
|
|
21
21
|
structureCoverage: number
|
|
22
22
|
/** first and last transcript residue the alignment covers, 1-based
|
|
23
|
-
* inclusive; 0 when nothing aligned. A structure is usually a fragment,
|
|
24
|
-
* which part of the protein it
|
|
23
|
+
* inclusive; 0 when nothing aligned. A structure is usually a fragment, so
|
|
24
|
+
* these show which part of the protein it contains. */
|
|
25
25
|
transcriptStart: number
|
|
26
26
|
transcriptEnd: number
|
|
27
27
|
}
|
package/src/alphaFoldModels.ts
CHANGED
|
@@ -78,11 +78,11 @@ export async function fetchAlphaFoldModels(
|
|
|
78
78
|
|
|
79
79
|
/**
|
|
80
80
|
* The model to open for a gene's transcripts: one folded from exactly a
|
|
81
|
-
* transcript's translation, canonical first, so
|
|
82
|
-
*
|
|
81
|
+
* transcript's translation, canonical first, so every residue maps to itself;
|
|
82
|
+
* else the canonical model; else the longest isoform model.
|
|
83
83
|
*
|
|
84
|
-
* Takes any record of sequences, since
|
|
85
|
-
*
|
|
84
|
+
* Takes any record of sequences, since a caller may know one translation rather
|
|
85
|
+
* than a gene's isoforms.
|
|
86
86
|
*/
|
|
87
87
|
export function pickAlphaFoldModel(
|
|
88
88
|
models: AlphaFoldModel[],
|
|
@@ -24,13 +24,13 @@ export function interactionMatchesMappedEntity(
|
|
|
24
24
|
}
|
|
25
25
|
|
|
26
26
|
export interface EntitySelection extends ScoredAlignment {
|
|
27
|
-
/** index
|
|
27
|
+
/** index of the chosen entity in the candidate array */
|
|
28
28
|
index: number
|
|
29
29
|
}
|
|
30
30
|
|
|
31
31
|
export interface ScoredAlignment {
|
|
32
|
-
/** alignment of the transcript against the entity
|
|
33
|
-
*
|
|
32
|
+
/** alignment of the transcript against the entity, with stop codons
|
|
33
|
+
* stripped from both */
|
|
34
34
|
alignment: PairwiseAlignment
|
|
35
35
|
/** identical aligned residues */
|
|
36
36
|
matches: number
|
|
@@ -56,8 +56,7 @@ export interface EntityCandidate {
|
|
|
56
56
|
* usually is: on 1H26 the 11-residue p53 peptide matches 11 while CDK2 accrues
|
|
57
57
|
* 58 scattered identities, and on 4ZZJ SIRT1 beats the 7-residue p53 peptide
|
|
58
58
|
* 63 to 6. The Smith-Waterman score is no better there (56 vs 58). Dividing
|
|
59
|
-
* by length
|
|
60
|
-
* gene's product: the peptide scores 0.69 and 0.50, the partners 0.19 and
|
|
59
|
+
* by the shorter length identifies the chain that *is* this gene's product: the peptide scores 0.69 and 0.50, the partners 0.19 and
|
|
61
60
|
* 0.17, and across a ribosome's 55 chains no decoy passes 0.29.
|
|
62
61
|
*
|
|
63
62
|
* Dividing by the *entity's* length alone penalised a fusion construct: a
|
|
@@ -136,18 +135,16 @@ export function alignTranscriptToEntity(
|
|
|
136
135
|
}
|
|
137
136
|
|
|
138
137
|
/**
|
|
139
|
-
* Pick
|
|
138
|
+
* Pick the polymer entity of a structure that is the transcript's protein.
|
|
140
139
|
*
|
|
141
|
-
*
|
|
142
|
-
*
|
|
143
|
-
*
|
|
144
|
-
*
|
|
145
|
-
*
|
|
146
|
-
* sequence (see `explainedFraction`). Nucleic-acid entities are never
|
|
147
|
-
* candidates.
|
|
140
|
+
* Taking entity `[0]` mis-maps every heteromeric, protein-DNA or
|
|
141
|
+
* processed-peptide structure where the protein is another chain. An exact
|
|
142
|
+
* sequence match wins outright; otherwise the entity with the highest identity
|
|
143
|
+
* over the shorter sequence wins (see `explainedFraction`). Nucleic-acid
|
|
144
|
+
* entities are never candidates.
|
|
148
145
|
*
|
|
149
|
-
* Returns `undefined` only when there is nothing to map
|
|
150
|
-
* protein
|
|
146
|
+
* Returns `undefined` only when there is nothing to map: no transcript, or no
|
|
147
|
+
* protein entity. It never falls back to another entity.
|
|
151
148
|
*/
|
|
152
149
|
export function chooseMappedEntity(
|
|
153
150
|
transcript: string,
|