openfda-mcp-server 1.0.0 → 1.2.0

package/README.md

@@ -7,6 +7,8 @@ An MCP (Model Context Protocol) server that provides access to U.S. FDA public d
 - **10 FDA Tools**: Query drug and device databases through a standardized MCP interface
 - **Drug Tools**: Adverse events (FAERS), labels, NDC directory, recalls, Drugs@FDA, shortages
 - **Device Tools**: 510(k) clearances, classifications, adverse events (MDR), recalls
+- **Individual Record Lookup**: Retrieve specific reports by ID (safety report ID, set ID, MDR report number)
+- **Advanced Filtering**: Filter drug labels by boxed warnings, request specific label sections
 - **Rate Limit Aware**: Supports authenticated requests for higher rate limits (120k/hour vs 1k/hour)
 - **TypeScript**: Fully typed with Zod schema validation
 
@@ -52,23 +54,69 @@ Get a free API key at: https://open.fda.gov/apis/authentication/
 
 ### Drug Tools
 
-| Tool                         | Description                                  |
-| ---------------------------- | -------------------------------------------- |
-| `search_drug_adverse_events` | Search FAERS for drug safety reports         |
-| `search_drug_labels`         | Search drug labeling/prescribing information |
-| `search_drug_ndc`            | Search the National Drug Code directory      |
-| `search_drug_recalls`        | Search drug recall enforcement reports       |
-| `search_drugs_at_fda`        | Search approved drug applications            |
-| `search_drug_shortages`      | Search current and resolved drug shortages   |
+| Tool                         | Description                                                                                            |
+| ---------------------------- | ------------------------------------------------------------------------------------------------------ |
+| `search_drug_adverse_events` | Search FAERS for drug safety reports. Retrieve specific report by `safetyReportId`.                    |
+| `search_drug_labels`         | Search drug labeling/prescribing info. Get by `setId`, filter by `hasBoxedWarning`, select `sections`. |
+| `search_drug_ndc`            | Search the National Drug Code directory                                                                |
+| `search_drug_recalls`        | Search drug recall enforcement reports                                                                 |
+| `search_drugs_at_fda`        | Search approved drug applications                                                                      |
+| `search_drug_shortages`      | Search current and resolved drug shortages                                                             |
 
 ### Device Tools
 
-| Tool                            | Description                              |
-| ------------------------------- | ---------------------------------------- |
-| `search_device_510k`            | Search 510(k) premarket notifications    |
-| `search_device_classifications` | Search device classification database    |
-| `search_device_adverse_events`  | Search MDR adverse event reports         |
-| `search_device_recalls`         | Search device recall enforcement reports |
+| Tool                            | Description                                                                   |
+| ------------------------------- | ----------------------------------------------------------------------------- |
+| `search_device_510k`            | Search 510(k) premarket notifications                                         |
+| `search_device_classifications` | Search device classification database                                         |
+| `search_device_adverse_events`  | Search MDR adverse event reports. Retrieve specific report by `reportNumber`. |
+| `search_device_recalls`         | Search device recall enforcement reports                                      |
+
+## Tool Parameters
+
+### search_drug_labels
+
+| Parameter          | Type     | Description                                                  |
+| ------------------ | -------- | ------------------------------------------------------------ |
+| `setId`            | string   | Retrieve a specific label by its unique set_id               |
+| `drugName`         | string   | Drug brand or generic name                                   |
+| `indication`       | string   | Medical indication or use case                               |
+| `activeIngredient` | string   | Active ingredient/substance name                             |
+| `route`            | string   | Route of administration (e.g., 'oral', 'intravenous')        |
+| `hasBoxedWarning`  | boolean  | Filter for drugs with boxed warnings (most serious warnings) |
+| `sections`         | string[] | Specific label sections to return (see below)                |
+| `limit`            | number   | Maximum results (1-100)                                      |
+| `skip`             | number   | Number of results to skip for pagination                     |
+
+**Available sections**: `indications_and_usage`, `dosage_and_administration`, `contraindications`, `warnings`, `warnings_and_cautions`, `adverse_reactions`, `drug_interactions`, `clinical_pharmacology`, `mechanism_of_action`, `pharmacokinetics`, `overdosage`, `description`, `how_supplied`, `storage_and_handling`, `boxed_warning`
+
+### search_drug_adverse_events
+
+| Parameter        | Type    | Description                                        |
+| ---------------- | ------- | -------------------------------------------------- |
+| `safetyReportId` | string  | Retrieve a specific FAERS report by its 8-digit ID |
+| `drugName`       | string  | Drug or product name to search                     |
+| `reaction`       | string  | Adverse reaction (e.g., 'headache', 'nausea')      |
+| `manufacturer`   | string  | Drug manufacturer name                             |
+| `serious`        | boolean | Filter for serious adverse events only             |
+| `dateFrom`       | string  | Start date (YYYY-MM-DD)                            |
+| `dateTo`         | string  | End date (YYYY-MM-DD)                              |
+| `limit`          | number  | Maximum results (1-100)                            |
+| `skip`           | number  | Number of results to skip for pagination           |
+
+### search_device_adverse_events
+
+| Parameter          | Type   | Description                                     |
+| ------------------ | ------ | ----------------------------------------------- |
+| `reportNumber`     | string | Retrieve a specific MDR report by report number |
+| `deviceName`       | string | Device generic name                             |
+| `brandName`        | string | Device brand name                               |
+| `manufacturerName` | string | Device manufacturer name                        |
+| `eventType`        | string | Type: 'Injury', 'Malfunction', 'Death', 'Other' |
+| `dateFrom`         | string | Start date (YYYY-MM-DD)                         |
+| `dateTo`           | string | End date (YYYY-MM-DD)                           |
+| `limit`            | number | Maximum results (1-100)                         |
+| `skip`             | number | Number of results to skip for pagination        |
 
 ## Usage Examples
 
@@ -78,6 +126,24 @@ Get a free API key at: https://open.fda.gov/apis/authentication/
 Find adverse events for aspirin in the last year that were serious
 ```
 
+### Get a specific adverse event report
+
+```
+Retrieve FAERS report with safety report ID 10003641
+```
+
+### Search for drugs with boxed warnings
+
+```
+Find all drugs with boxed warnings related to cardiovascular risks
+```
+
+### Get specific label sections
+
+```
+Get the boxed_warning and contraindications sections for warfarin
+```
+
 ### Search for drug recalls
 
 ```
@@ -90,6 +156,12 @@ Search for Class I drug recalls from Pfizer
 Find 510(k) clearances for cardiac pacemakers
 ```
 
+### Get a specific device adverse event report
+
+```
+Retrieve MDR report number 2649622-2020-08294
+```
+
 ### Search for device adverse events
 
 ```
@@ -164,7 +236,7 @@ pnpm build
 ## Programmatic Usage
 
 ```typescript
-import { createOpenFDAServer, handleSearchDrugAdverseEvents } from "openfda-mcp-server/lib"
+import { createOpenFDAServer, handleSearchDrugAdverseEvents, handleSearchDrugLabels } from "openfda-mcp-server/lib"
 
 // Create a custom server
 const server = createOpenFDAServer({
@@ -172,12 +244,29 @@ const server = createOpenFDAServer({
   version: "1.0.0",
 })
 
-// Or use handlers directly
-const result = await handleSearchDrugAdverseEvents({
+// Search for adverse events
+const adverseEvents = await handleSearchDrugAdverseEvents({
   drugName: "aspirin",
   serious: true,
   limit: 10,
 })
+
+// Get a specific adverse event by ID
+const specificReport = await handleSearchDrugAdverseEvents({
+  safetyReportId: "10003641",
+})
+
+// Search for drugs with boxed warnings
+const boxedWarningDrugs = await handleSearchDrugLabels({
+  hasBoxedWarning: true,
+  limit: 10,
+})
+
+// Get specific sections of a drug label
+const warfarinLabel = await handleSearchDrugLabels({
+  setId: "0cbce382-9c88-4f58-ae0f-532a841e8f95",
+  sections: ["boxed_warning", "contraindications", "adverse_reactions"],
+})
 ```
 
 ## API Rate Limits
@@ -194,5 +283,7 @@ MIT
 ## Acknowledgments
 
 - [OpenFDA](https://open.fda.gov/) - FDA open data API
-- [FastMCP](https://github.com/jordanburke/fastmcp) - MCP server framework
-- Based on [OpenFDA-MCP-Server](https://github.com/Augmented-Nature/OpenFDA-MCP-Server) concept
+
+---
+
+**Sponsored by <a href="https://sapientsai.com/"><img src="https://sapientsai.com/images/logo.svg" alt="SapientsAI" width="20" style="vertical-align: middle;"> SapientsAI</a>** — Building agentic AI for businesses

package/dist/defineProperty-BEGP2H1W.js

@@ -0,0 +1 @@
+function e(t){"@babel/helpers - typeof";return e=typeof Symbol==`function`&&typeof Symbol.iterator==`symbol`?function(e){return typeof e}:function(e){return e&&typeof Symbol==`function`&&e.constructor===Symbol&&e!==Symbol.prototype?`symbol`:typeof e},e(t)}function t(t,n){if(e(t)!=`object`||!t)return t;var r=t[Symbol.toPrimitive];if(r!==void 0){var i=r.call(t,n||`default`);if(e(i)!=`object`)return i;throw TypeError(`@@toPrimitive must return a primitive value.`)}return(n===`string`?String:Number)(t)}function n(n){var r=t(n,`string`);return e(r)==`symbol`?r:r+``}function r(e,t,r){return(t=n(t))in e?Object.defineProperty(e,t,{value:r,enumerable:!0,configurable:!0,writable:!0}):e[t]=r,e}export{r as t};

package/dist/handlers/bulk-data-handlers.d.ts

@@ -0,0 +1,108 @@
+import { FDAToolResponse } from "../types/fda.js";
+
+//#region src/handlers/bulk-data-handlers.d.ts
+type OrangeBookSearchParams = {
+  drugName?: string;
+  applicant?: string;
+  applNo?: string;
+  teCode?: string;
+  limit?: number;
+  skip?: number;
+};
+type FormattedOrangeBookProduct = {
+  tradeName: string;
+  ingredient: string;
+  applicant: string;
+  applicantFullName: string;
+  applType: string;
+  applNo: string;
+  productNo: string;
+  dfRoute: string;
+  teCode: string;
+  approvalDate: string;
+  rld: string;
+  type: string;
+  patentCount: number;
+  exclusivityCount: number;
+};
+declare function handleSearchOrangeBook(params: OrangeBookSearchParams): Promise<FDAToolResponse<FormattedOrangeBookProduct[]>>;
+type OrangeBookPatentsParams = {
+  drugName?: string;
+  applNo?: string;
+  patentNo?: string;
+  limit?: number;
+  skip?: number;
+};
+type FormattedOrangeBookPatent = {
+  patentNo: string;
+  patentExpireDate: string;
+  drugSubstanceFlag: string;
+  drugProductFlag: string;
+  patentUseCode: string;
+  applType: string;
+  applNo: string;
+  productNo: string;
+  tradeName: string;
+  ingredient: string;
+  submissionDate: string;
+  exclusivities: Array<{
+    code: string;
+    date: string;
+  }>;
+};
+declare function handleSearchOrangeBookPatents(params: OrangeBookPatentsParams): Promise<FDAToolResponse<FormattedOrangeBookPatent[]>>;
+type PurpleBookSearchParams = {
+  productName?: string;
+  applicant?: string;
+  blaNumber?: string;
+  licenseType?: "351(a)" | "351(k)";
+  biosimilar?: boolean;
+  interchangeable?: boolean;
+  limit?: number;
+  skip?: number;
+};
+type FormattedPurpleBookEntry = {
+  blaNumber: string;
+  proprietaryName: string;
+  properName: string;
+  applicant: string;
+  blaType: string;
+  strength: string;
+  dosageForm: string;
+  route: string;
+  status: string;
+  licensingStatus: string;
+  biosimilar: boolean;
+  interchangeable: boolean;
+  referenceProductBla: string;
+  referenceProductName: string;
+  approvalDate: string;
+};
+declare function handleSearchPurpleBook(params: PurpleBookSearchParams): Promise<FDAToolResponse<FormattedPurpleBookEntry[]>>;
+type DrugPatentExpiryParams = {
+  drugName?: string;
+  applNo?: string;
+  includeExclusivity?: boolean;
+  includePurpleBook?: boolean;
+  limit?: number;
+  skip?: number;
+};
+type PatentExpiryEntry = {
+  source: string;
+  tradeName: string;
+  ingredient: string;
+  applNo: string;
+  patentNo: string;
+  patentExpireDate: string;
+  drugSubstanceFlag: string;
+  drugProductFlag: string;
+  patentUseCode: string;
+  exclusivities: Array<{
+    code: string;
+    date: string;
+  }>;
+};
+declare function handleSearchDrugPatentExpiry(params: DrugPatentExpiryParams): Promise<FDAToolResponse<PatentExpiryEntry[]>>;
+//#endregion
+export { DrugPatentExpiryParams, OrangeBookPatentsParams, OrangeBookSearchParams, PurpleBookSearchParams, handleSearchDrugPatentExpiry, handleSearchOrangeBook, handleSearchOrangeBookPatents, handleSearchPurpleBook };
+//# sourceMappingURL=bulk-data-handlers.d.ts.map

package/dist/handlers/bulk-data-handlers.js

@@ -0,0 +1,2 @@
+import{loggers as e}from"../utils/logger.js";import{bulkDataClient as t}from"../utils/bulk-data-client.js";function n(e,t){return t?e.toLowerCase().includes(t.toLowerCase()):!0}function r(e){return`${e.applType}-${e.applNo}-${e.productNo}`}function i(e,t,n){let r=e.length,i=n??0,a=Math.min(t??10,100);return{items:e.slice(i,i+a),total:r}}const a={name:`FDA Orange Book`,lastUpdated:`Monthly`,url:`https://www.fda.gov/drugs/drug-approvals-and-databases/approved-drug-products-therapeutic-equivalence-evaluations-orange-book`},o={name:`FDA Purple Book`,lastUpdated:`Monthly`,url:`https://purplebooksearch.fda.gov/`};async function s(o){e.tools(`searchOrangeBook`,o);try{let{products:e,patents:s,exclusivities:c}=await t.getOrangeBookData(),l=new Map;for(let e of s){let t=r(e);l.set(t,(l.get(t)??0)+1)}let u=new Map;for(let e of c){let t=r(e);u.set(t,(u.get(t)??0)+1)}let{items:d,total:f}=i(e.filter(e=>!(!n(e.tradeName,o.drugName)&&!n(e.ingredient,o.drugName)||!n(e.applicant,o.applicant)&&!n(e.applicantFullName,o.applicant)||o.applNo&&e.applNo!==o.applNo||!n(e.teCode,o.teCode))),o.limit,o.skip);return{success:!0,data:d.map(e=>{let t=r(e);return{tradeName:e.tradeName,ingredient:e.ingredient,applicant:e.applicant,applicantFullName:e.applicantFullName,applType:e.applType,applNo:e.applNo,productNo:e.productNo,dfRoute:e.dfRoute,teCode:e.teCode,approvalDate:e.approvalDate,rld:e.rld,type:e.type,patentCount:l.get(t)??0,exclusivityCount:u.get(t)??0}}),totalResults:f,displayedResults:d.length,dataSource:a}}catch(e){return{success:!1,error:e instanceof Error?e.message:String(e)}}}async function c(o){e.tools(`searchOrangeBookPatents`,o);try{let{products:e,patents:s,exclusivities:c}=await t.getOrangeBookData(),l=new Map;for(let t of e)l.set(r(t),t);let u=new Map;for(let e of c){let t=r(e),n=u.get(t)??[];n.push(e),u.set(t,n)}let{items:d,total:f}=i(s.filter(e=>{if(o.patentNo&&e.patentNo!==o.patentNo||o.applNo&&e.applNo!==o.applNo)return!1;if(o.drugName){let t=l.get(r(e));if(!t||!n(t.tradeName,o.drugName)&&!n(t.ingredient,o.drugName))return!1}return!0}),o.limit,o.skip);return{success:!0,data:d.map(e=>{let t=r(e),n=l.get(t),i=u.get(t)??[];return{patentNo:e.patentNo,patentExpireDate:e.patentExpireDate,drugSubstanceFlag:e.drugSubstanceFlag,drugProductFlag:e.drugProductFlag,patentUseCode:e.patentUseCode,applType:e.applType,applNo:e.applNo,productNo:e.productNo,tradeName:n?.tradeName??``,ingredient:n?.ingredient??``,submissionDate:e.submissionDate,exclusivities:i.map(e=>({code:e.exclusivityCode,date:e.exclusivityDate}))}}),totalResults:f,displayedResults:d.length,dataSource:a}}catch(e){return{success:!1,error:e instanceof Error?e.message:String(e)}}}async function l(r){e.tools(`searchPurpleBook`,r);try{let{items:e,total:a}=i((await t.getPurpleBookData()).filter(e=>!(!n(e.proprietaryName,r.productName)&&!n(e.properName,r.productName)||!n(e.applicant,r.applicant)||r.blaNumber&&e.blaNumber!==r.blaNumber||r.licenseType&&e.blaType!==r.licenseType||r.biosimilar!==void 0&&e.biosimilar!==r.biosimilar||r.interchangeable!==void 0&&e.interchangeable!==r.interchangeable)),r.limit,r.skip);return{success:!0,data:e.map(e=>({blaNumber:e.blaNumber,proprietaryName:e.proprietaryName,properName:e.properName,applicant:e.applicant,blaType:e.blaType,strength:e.strength,dosageForm:e.dosageForm,route:e.route,status:e.status,licensingStatus:e.licensingStatus,biosimilar:e.biosimilar,interchangeable:e.interchangeable,referenceProductBla:e.referenceProductBla,referenceProductName:e.referenceProductProprietaryName,approvalDate:e.approvalDate})),totalResults:a,displayedResults:e.length,dataSource:o}}catch(e){return{success:!1,error:e instanceof Error?e.message:String(e)}}}async function u(o){e.tools(`searchDrugPatentExpiry`,o);try{let s=o.includeExclusivity!==!1,c=o.includePurpleBook===!0,{products:l,patents:u,exclusivities:d}=await t.getOrangeBookData(),f=new Map;for(let e of l)f.set(r(e),e);let p=new Map;if(s)for(let e of d){let t=r(e),n=p.get(t)??[];n.push(e),p.set(t,n)}let m=u.filter(e=>{if(o.applNo&&e.applNo!==o.applNo)return!1;if(o.drugName){let t=f.get(r(e));if(!t||!n(t.tradeName,o.drugName)&&!n(t.ingredient,o.drugName))return!1}return!0}).map(e=>{let t=r(e),n=f.get(t),i=s?p.get(t)??[]:[];return{source:`Orange Book`,tradeName:n?.tradeName??``,ingredient:n?.ingredient??``,applNo:e.applNo,patentNo:e.patentNo,patentExpireDate:e.patentExpireDate,drugSubstanceFlag:e.drugSubstanceFlag,drugProductFlag:e.drugProductFlag,patentUseCode:e.patentUseCode,exclusivities:i.map(e=>({code:e.exclusivityCode,date:e.exclusivityDate}))}});if(c)try{let e=(await t.getPurpleBookData()).filter(e=>!(o.drugName&&!n(e.proprietaryName,o.drugName)&&!n(e.properName,o.drugName)||o.applNo&&e.blaNumber!==o.applNo));for(let t of e)m.push({source:`Purple Book`,tradeName:t.proprietaryName,ingredient:t.properName,applNo:t.blaNumber,patentNo:``,patentExpireDate:``,drugSubstanceFlag:``,drugProductFlag:``,patentUseCode:``,exclusivities:[]})}catch(t){e.bulk(`Purple Book data unavailable: ${t instanceof Error?t.message:String(t)}`)}m.sort((e,t)=>!e.patentExpireDate&&!t.patentExpireDate?0:e.patentExpireDate?t.patentExpireDate?e.patentExpireDate.localeCompare(t.patentExpireDate):-1:1);let{items:h,total:g}=i(m,o.limit,o.skip);return{success:!0,data:h,totalResults:g,displayedResults:h.length,dataSource:a}}catch(e){return{success:!1,error:e instanceof Error?e.message:String(e)}}}export{u as handleSearchDrugPatentExpiry,s as handleSearchOrangeBook,c as handleSearchOrangeBookPatents,l as handleSearchPurpleBook};
+//# sourceMappingURL=bulk-data-handlers.js.map

package/dist/handlers/bulk-data-handlers.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"bulk-data-handlers.js","names":[],"sources":["../../src/handlers/bulk-data-handlers.ts"],"sourcesContent":["/**\n * Bulk Data Handlers\n * Query handlers for FDA Orange Book and Purple Book data\n */\n\nimport type { FDAToolResponse, OrangeBookExclusivity, OrangeBookPatent, OrangeBookProduct } from \"../types/fda.js\"\nimport { bulkDataClient } from \"../utils/bulk-data-client.js\"\nimport { loggers } from \"../utils/logger.js\"\n\n// Helper for case-insensitive substring matching\nfunction matchesFilter(value: string, filter: string | undefined): boolean {\n  if (!filter) return true\n  return value.toLowerCase().includes(filter.toLowerCase())\n}\n\n// Join key for Orange Book records\nfunction obJoinKey(record: { applType: string; applNo: string; productNo: string }): string {\n  return `${record.applType}-${record.applNo}-${record.productNo}`\n}\n\n// Default pagination values\nconst DEFAULT_LIMIT = 10\nconst MAX_LIMIT = 100\n\nfunction applyPagination<T>(items: T[], limit?: number, skip?: number): { items: T[]; total: number } {\n  const total = items.length\n  const effectiveSkip = skip ?? 0\n  const effectiveLimit = Math.min(limit ?? DEFAULT_LIMIT, MAX_LIMIT)\n  return {\n    items: items.slice(effectiveSkip, effectiveSkip + effectiveLimit),\n    total,\n  }\n}\n\nconst ORANGE_BOOK_SOURCE = {\n  name: \"FDA Orange Book\",\n  lastUpdated: \"Monthly\",\n  url: \"https://www.fda.gov/drugs/drug-approvals-and-databases/approved-drug-products-therapeutic-equivalence-evaluations-orange-book\",\n}\n\nconst PURPLE_BOOK_SOURCE = {\n  name: \"FDA Purple Book\",\n  lastUpdated: \"Monthly\",\n  url: \"https://purplebooksearch.fda.gov/\",\n}\n\n// ============================================================\n// search_fda_orange_book\n// ============================================================\n\nexport type OrangeBookSearchParams = {\n  drugName?: string\n  applicant?: string\n  applNo?: string\n  teCode?: string\n  limit?: number\n  skip?: number\n}\n\ntype FormattedOrangeBookProduct = {\n  tradeName: string\n  ingredient: string\n  applicant: string\n  applicantFullName: string\n  applType: string\n  applNo: string\n  productNo: string\n  dfRoute: string\n  teCode: string\n  approvalDate: string\n  rld: string\n  type: string\n  patentCount: number\n  exclusivityCount: number\n}\n\nexport async function handleSearchOrangeBook(\n  params: OrangeBookSearchParams,\n): Promise<FDAToolResponse<FormattedOrangeBookProduct[]>> {\n  loggers.tools(\"searchOrangeBook\", params)\n\n  try {\n    const { products, patents, exclusivities } = await bulkDataClient.getOrangeBookData()\n\n    // Build patent/exclusivity count maps\n    const patentCounts = new Map<string, number>()\n    for (const p of patents) {\n      const key = obJoinKey(p)\n      patentCounts.set(key, (patentCounts.get(key) ?? 0) + 1)\n    }\n\n    const exclusivityCounts = new Map<string, number>()\n    for (const e of exclusivities) {\n      const key = obJoinKey(e)\n      exclusivityCounts.set(key, (exclusivityCounts.get(key) ?? 0) + 1)\n    }\n\n    // Filter products\n    const filtered = products.filter((p) => {\n      if (!matchesFilter(p.tradeName, params.drugName) && !matchesFilter(p.ingredient, params.drugName)) return false\n      if (!matchesFilter(p.applicant, params.applicant) && !matchesFilter(p.applicantFullName, params.applicant))\n        return false\n      if (params.applNo && p.applNo !== params.applNo) return false\n      if (!matchesFilter(p.teCode, params.teCode)) return false\n      return true\n    })\n\n    const { items, total } = applyPagination(filtered, params.limit, params.skip)\n\n    const formatted: FormattedOrangeBookProduct[] = items.map((p) => {\n      const key = obJoinKey(p)\n      return {\n        tradeName: p.tradeName,\n        ingredient: p.ingredient,\n        applicant: p.applicant,\n        applicantFullName: p.applicantFullName,\n        applType: p.applType,\n        applNo: p.applNo,\n        productNo: p.productNo,\n        dfRoute: p.dfRoute,\n        teCode: p.teCode,\n        approvalDate: p.approvalDate,\n        rld: p.rld,\n        type: p.type,\n        patentCount: patentCounts.get(key) ?? 0,\n        exclusivityCount: exclusivityCounts.get(key) ?? 0,\n      }\n    })\n\n    return {\n      success: true,\n      data: formatted,\n      totalResults: total,\n      displayedResults: items.length,\n      dataSource: ORANGE_BOOK_SOURCE,\n    }\n  } catch (error) {\n    return {\n      success: false,\n      error: error instanceof Error ? error.message : String(error),\n    }\n  }\n}\n\n// ============================================================\n// search_fda_orange_book_patents\n// ============================================================\n\nexport type OrangeBookPatentsParams = {\n  drugName?: string\n  applNo?: string\n  patentNo?: string\n  limit?: number\n  skip?: number\n}\n\ntype FormattedOrangeBookPatent = {\n  patentNo: string\n  patentExpireDate: string\n  drugSubstanceFlag: string\n  drugProductFlag: string\n  patentUseCode: string\n  applType: string\n  applNo: string\n  productNo: string\n  tradeName: string\n  ingredient: string\n  submissionDate: string\n  exclusivities: Array<{ code: string; date: string }>\n}\n\nexport async function handleSearchOrangeBookPatents(\n  params: OrangeBookPatentsParams,\n): Promise<FDAToolResponse<FormattedOrangeBookPatent[]>> {\n  loggers.tools(\"searchOrangeBookPatents\", params)\n\n  try {\n    const { products, patents, exclusivities } = await bulkDataClient.getOrangeBookData()\n\n    // Build product lookup by join key\n    const productMap = new Map<string, OrangeBookProduct>()\n    for (const p of products) {\n      productMap.set(obJoinKey(p), p)\n    }\n\n    // Build exclusivity lookup by join key\n    const exclusivityMap = new Map<string, OrangeBookExclusivity[]>()\n    for (const e of exclusivities) {\n      const key = obJoinKey(e)\n      const existing = exclusivityMap.get(key) ?? []\n      existing.push(e)\n      exclusivityMap.set(key, existing)\n    }\n\n    // Filter patents\n    const filtered = patents.filter((pat) => {\n      if (params.patentNo && pat.patentNo !== params.patentNo) return false\n      if (params.applNo && pat.applNo !== params.applNo) return false\n\n      if (params.drugName) {\n        const product = productMap.get(obJoinKey(pat))\n        if (!product) return false\n        if (!matchesFilter(product.tradeName, params.drugName) && !matchesFilter(product.ingredient, params.drugName))\n          return false\n      }\n\n      return true\n    })\n\n    const { items, total } = applyPagination(filtered, params.limit, params.skip)\n\n    const formatted: FormattedOrangeBookPatent[] = items.map((pat) => {\n      const key = obJoinKey(pat)\n      const product = productMap.get(key)\n      const excl = exclusivityMap.get(key) ?? []\n\n      return {\n        patentNo: pat.patentNo,\n        patentExpireDate: pat.patentExpireDate,\n        drugSubstanceFlag: pat.drugSubstanceFlag,\n        drugProductFlag: pat.drugProductFlag,\n        patentUseCode: pat.patentUseCode,\n        applType: pat.applType,\n        applNo: pat.applNo,\n        productNo: pat.productNo,\n        tradeName: product?.tradeName ?? \"\",\n        ingredient: product?.ingredient ?? \"\",\n        submissionDate: pat.submissionDate,\n        exclusivities: excl.map((e) => ({ code: e.exclusivityCode, date: e.exclusivityDate })),\n      }\n    })\n\n    return {\n      success: true,\n      data: formatted,\n      totalResults: total,\n      displayedResults: items.length,\n      dataSource: ORANGE_BOOK_SOURCE,\n    }\n  } catch (error) {\n    return {\n      success: false,\n      error: error instanceof Error ? error.message : String(error),\n    }\n  }\n}\n\n// ============================================================\n// search_fda_purple_book\n// ============================================================\n\nexport type PurpleBookSearchParams = {\n  productName?: string\n  applicant?: string\n  blaNumber?: string\n  licenseType?: \"351(a)\" | \"351(k)\"\n  biosimilar?: boolean\n  interchangeable?: boolean\n  limit?: number\n  skip?: number\n}\n\ntype FormattedPurpleBookEntry = {\n  blaNumber: string\n  proprietaryName: string\n  properName: string\n  applicant: string\n  blaType: string\n  strength: string\n  dosageForm: string\n  route: string\n  status: string\n  licensingStatus: string\n  biosimilar: boolean\n  interchangeable: boolean\n  referenceProductBla: string\n  referenceProductName: string\n  approvalDate: string\n}\n\nexport async function handleSearchPurpleBook(\n  params: PurpleBookSearchParams,\n): Promise<FDAToolResponse<FormattedPurpleBookEntry[]>> {\n  loggers.tools(\"searchPurpleBook\", params)\n\n  try {\n    const entries = await bulkDataClient.getPurpleBookData()\n\n    const filtered = entries.filter((e) => {\n      if (!matchesFilter(e.proprietaryName, params.productName) && !matchesFilter(e.properName, params.productName))\n        return false\n      if (!matchesFilter(e.applicant, params.applicant)) return false\n      if (params.blaNumber && e.blaNumber !== params.blaNumber) return false\n      if (params.licenseType && e.blaType !== params.licenseType) return false\n      if (params.biosimilar !== undefined && e.biosimilar !== params.biosimilar) return false\n      if (params.interchangeable !== undefined && e.interchangeable !== params.interchangeable) return false\n      return true\n    })\n\n    const { items, total } = applyPagination(filtered, params.limit, params.skip)\n\n    const formatted: FormattedPurpleBookEntry[] = items.map((e) => ({\n      blaNumber: e.blaNumber,\n      proprietaryName: e.proprietaryName,\n      properName: e.properName,\n      applicant: e.applicant,\n      blaType: e.blaType,\n      strength: e.strength,\n      dosageForm: e.dosageForm,\n      route: e.route,\n      status: e.status,\n      licensingStatus: e.licensingStatus,\n      biosimilar: e.biosimilar,\n      interchangeable: e.interchangeable,\n      referenceProductBla: e.referenceProductBla,\n      referenceProductName: e.referenceProductProprietaryName,\n      approvalDate: e.approvalDate,\n    }))\n\n    return {\n      success: true,\n      data: formatted,\n      totalResults: total,\n      displayedResults: items.length,\n      dataSource: PURPLE_BOOK_SOURCE,\n    }\n  } catch (error) {\n    return {\n      success: false,\n      error: error instanceof Error ? error.message : String(error),\n    }\n  }\n}\n\n// ============================================================\n// search_fda_drug_patent_expiry\n// ============================================================\n\nexport type DrugPatentExpiryParams = {\n  drugName?: string\n  applNo?: string\n  includeExclusivity?: boolean\n  includePurpleBook?: boolean\n  limit?: number\n  skip?: number\n}\n\ntype PatentExpiryEntry = {\n  source: string\n  tradeName: string\n  ingredient: string\n  applNo: string\n  patentNo: string\n  patentExpireDate: string\n  drugSubstanceFlag: string\n  drugProductFlag: string\n  patentUseCode: string\n  exclusivities: Array<{ code: string; date: string }>\n}\n\nexport async function handleSearchDrugPatentExpiry(\n  params: DrugPatentExpiryParams,\n): Promise<FDAToolResponse<PatentExpiryEntry[]>> {\n  loggers.tools(\"searchDrugPatentExpiry\", params)\n\n  try {\n    const includeExclusivity = params.includeExclusivity !== false\n    const includePurpleBook = params.includePurpleBook === true\n\n    const { products, patents, exclusivities } = await bulkDataClient.getOrangeBookData()\n\n    // Build product lookup\n    const productMap = new Map<string, OrangeBookProduct>()\n    for (const p of products) {\n      productMap.set(obJoinKey(p), p)\n    }\n\n    // Build exclusivity lookup\n    const exclusivityMap = new Map<string, OrangeBookExclusivity[]>()\n    if (includeExclusivity) {\n      for (const e of exclusivities) {\n        const key = obJoinKey(e)\n        const existing = exclusivityMap.get(key) ?? []\n        existing.push(e)\n        exclusivityMap.set(key, existing)\n      }\n    }\n\n    // Filter patents by drug name / applNo\n    const filteredPatents = patents.filter((pat) => {\n      if (params.applNo && pat.applNo !== params.applNo) return false\n      if (params.drugName) {\n        const product = productMap.get(obJoinKey(pat))\n        if (!product) return false\n        if (!matchesFilter(product.tradeName, params.drugName) && !matchesFilter(product.ingredient, params.drugName))\n          return false\n      }\n      return true\n    })\n\n    const entries: PatentExpiryEntry[] = filteredPatents.map((pat) => {\n      const key = obJoinKey(pat)\n      const product = productMap.get(key)\n      const excl = includeExclusivity ? (exclusivityMap.get(key) ?? []) : []\n\n      return {\n        source: \"Orange Book\",\n        tradeName: product?.tradeName ?? \"\",\n        ingredient: product?.ingredient ?? \"\",\n        applNo: pat.applNo,\n        patentNo: pat.patentNo,\n        patentExpireDate: pat.patentExpireDate,\n        drugSubstanceFlag: pat.drugSubstanceFlag,\n        drugProductFlag: pat.drugProductFlag,\n        patentUseCode: pat.patentUseCode,\n        exclusivities: excl.map((e) => ({ code: e.exclusivityCode, date: e.exclusivityDate })),\n      }\n    })\n\n    // Optionally add Purple Book entries that match\n    if (includePurpleBook) {\n      try {\n        const purpleEntries = await bulkDataClient.getPurpleBookData()\n        const filteredPurple = purpleEntries.filter((e) => {\n          if (params.drugName) {\n            if (!matchesFilter(e.proprietaryName, params.drugName) && !matchesFilter(e.properName, params.drugName))\n              return false\n          }\n          if (params.applNo && e.blaNumber !== params.applNo) return false\n          return true\n        })\n\n        for (const pe of filteredPurple) {\n          entries.push({\n            source: \"Purple Book\",\n            tradeName: pe.proprietaryName,\n            ingredient: pe.properName,\n            applNo: pe.blaNumber,\n            patentNo: \"\",\n            patentExpireDate: \"\",\n            drugSubstanceFlag: \"\",\n            drugProductFlag: \"\",\n            patentUseCode: \"\",\n            exclusivities: [],\n          })\n        }\n      } catch (error) {\n        loggers.bulk(`Purple Book data unavailable: ${error instanceof Error ? error.message : String(error)}`)\n      }\n    }\n\n    // Sort by earliest expiry date (non-empty dates first)\n    entries.sort((a, b) => {\n      if (!a.patentExpireDate && !b.patentExpireDate) return 0\n      if (!a.patentExpireDate) return 1\n      if (!b.patentExpireDate) return -1\n      return a.patentExpireDate.localeCompare(b.patentExpireDate)\n    })\n\n    const { items, total } = applyPagination(entries, params.limit, params.skip)\n\n    return {\n      success: true,\n      data: items,\n      totalResults: total,\n      displayedResults: items.length,\n      dataSource: ORANGE_BOOK_SOURCE,\n    }\n  } catch (error) {\n    return {\n      success: false,\n      error: error instanceof Error ? error.message : String(error),\n    }\n  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package/dist/handlers/device-handlers.d.ts

@@ -1,7 +1,6 @@
 import { FDAToolResponse } from "../types/fda.js";
 
 //#region src/handlers/device-handlers.d.ts
-
 type Device510KParams = {
   deviceName?: string;
   applicant?: string;
@@ -50,6 +49,7 @@ type FormattedDeviceClassification = {
 };
 declare function handleSearchDeviceClassifications(params: DeviceClassificationParams): Promise<FDAToolResponse<FormattedDeviceClassification[]>>;
 type DeviceAdverseEventsParams = {
+  reportNumber?: string;
   deviceName?: string;
   brandName?: string;
   manufacturerName?: string;

package/dist/handlers/device-handlers.js

@@ -1 +1,2 @@
-import"../utils/logger.js";import"../api-client-BGnUXMwX.js";import{i as e,n as t,r as n,t as r}from"../device-handlers-D01LfIJk.js";export{r as handleSearchDevice510K,t as handleSearchDeviceAdverseEvents,n as handleSearchDeviceClassifications,e as handleSearchDeviceEnforcement};
+import{loggers as e}from"../utils/logger.js";import{fdaAPIClient as t}from"../utils/api-client.js";function n(e,t,n){if(!(!t&&!n))return`${e}:[${t?.replace(/-/g,``)??`*`}+TO+${n?.replace(/-/g,``)??`*`}]`}function r(e){return e.replace(/[+\-&|!(){}[\]^"~*?:\\]/g,`\\$&`).replace(/\s+/g,`+`)}function i(e){let t=e.filter(e=>e.value!==void 0&&e.value.trim()!==``);return t.length===0?``:t.map(e=>`${e.field}:"${r(e.value)}"`).join(`+AND+`)}function a(e,t=200){if(e)return e.length>t?e.substring(0,t)+`...`:e}function o(e){return{kNumber:e.k_number,deviceName:e.device_name??e.openfda?.device_name,applicant:e.applicant,productCode:e.product_code,clearanceType:e.clearance_type,decisionCode:e.decision_code,decisionDescription:e.decision_description,decisionDate:e.decision_date,dateReceived:e.date_received,city:e.city,state:e.state,country:e.country_code}}async function s(r){e.tools(`searchDevice510K`,r);try{let e={search:[i([{field:`device_name`,value:r.deviceName},{field:`applicant`,value:r.applicant},{field:`product_code`,value:r.productCode},{field:`clearance_type`,value:r.clearanceType}]),n(`decision_date`,r.decisionDateFrom,r.decisionDateTo)].filter(Boolean).join(`+AND+`)||void 0,limit:r.limit,skip:r.skip},a=await t.searchDevice510K(e),s=a.results??[];return{success:!0,data:s.map(o),totalResults:a.meta?.results?.total,displayedResults:s.length,searchParams:e,apiUsage:t.getRateLimitInfo()}}catch(e){return{success:!1,error:e instanceof Error?e.message:String(e)}}}function c(e){return{deviceName:e.device_name,deviceClass:e.device_class,definition:a(e.definition),medicalSpecialty:e.medical_specialty,medicalSpecialtyDescription:e.medical_specialty_description,productCode:e.product_code,regulationNumber:e.regulation_number,gmpExempt:e.gmp_exempt_flag===`Y`,implant:e.implant_flag===`Y`,lifeSustaining:e.life_sustain_support_flag===`Y`}}async function l(n){e.tools(`searchDeviceClassifications`,n);try{let e={search:i([{field:`device_name`,value:n.deviceName},{field:`device_class`,value:n.deviceClass},{field:`medical_specialty`,value:n.medicalSpecialty},{field:`product_code`,value:n.productCode},{field:`regulation_number`,value:n.regulationNumber}])||void 0,limit:n.limit,skip:n.skip},r=await t.searchDeviceClassifications(e),a=r.results??[];return{success:!0,data:a.map(c),totalResults:r.meta?.results?.total,displayedResults:a.length,searchParams:e,apiUsage:t.getRateLimitInfo()}}catch(e){return{success:!1,error:e instanceof Error?e.message:String(e)}}}function u(e){return{reportNumber:e.report_number,dateOfEvent:e.date_of_event,dateReceived:e.date_received,eventType:e.event_type,adverseEventFlag:e.adverse_event_flag===`Y`,productProblemFlag:e.product_problem_flag===`Y`,devices:e.device?.slice(0,3).map(e=>({brandName:e.brand_name,genericName:e.generic_name,manufacturerName:e.manufacturer_d_name,modelNumber:e.model_number,productCode:e.device_report_product_code,deviceClass:e.openfda?.device_class}))??[],mdrText:e.mdr_text?.slice(0,2).map(e=>({textType:e.text_type_code,text:a(e.text,300)}))??[]}}async function d(a){e.tools(`searchDeviceAdverseEvents`,a);try{if(a.reportNumber){let e={search:`report_number:"${r(a.reportNumber)}"`,limit:1},n=await t.searchDeviceAdverseEvents(e),i=n.results??[];return{success:!0,data:i.map(u),totalResults:n.meta?.results?.total,displayedResults:i.length,searchParams:e,apiUsage:t.getRateLimitInfo()}}let e={search:[i([{field:`device.generic_name`,value:a.deviceName},{field:`device.brand_name`,value:a.brandName},{field:`device.manufacturer_d_name`,value:a.manufacturerName},{field:`event_type`,value:a.eventType}]),n(`date_received`,a.dateFrom,a.dateTo)].filter(Boolean).join(`+AND+`)||void 0,limit:a.limit,skip:a.skip},o=await t.searchDeviceAdverseEvents(e),s=o.results??[];return{success:!0,data:s.map(u),totalResults:o.meta?.results?.total,displayedResults:s.length,searchParams:e,apiUsage:t.getRateLimitInfo()}}catch(e){return{success:!1,error:e instanceof Error?e.message:String(e)}}}function f(e){return{recallNumber:e.recall_number,recallingFirm:e.recalling_firm,classification:e.classification,status:e.status,productDescription:a(e.product_description),reasonForRecall:a(e.reason_for_recall),recallInitiationDate:e.recall_initiation_date,distributionPattern:a(e.distribution_pattern),city:e.city,state:e.state,deviceName:e.openfda?.device_name,deviceClass:e.openfda?.device_class}}async function p(r){e.tools(`searchDeviceEnforcement`,r);try{let e={search:[i([{field:`recalling_firm`,value:r.recallingFirm},{field:`product_description`,value:r.productDescription},{field:`classification`,value:r.classification},{field:`status`,value:r.status}]),n(`recall_initiation_date`,r.dateFrom,r.dateTo)].filter(Boolean).join(`+AND+`)||void 0,limit:r.limit,skip:r.skip},a=await t.searchDeviceEnforcement(e),o=a.results??[];return{success:!0,data:o.map(f),totalResults:a.meta?.results?.total,displayedResults:o.length,searchParams:e,apiUsage:t.getRateLimitInfo()}}catch(e){return{success:!1,error:e instanceof Error?e.message:String(e)}}}export{s as handleSearchDevice510K,d as handleSearchDeviceAdverseEvents,l as handleSearchDeviceClassifications,p as handleSearchDeviceEnforcement};
+//# sourceMappingURL=device-handlers.js.map

package/dist/handlers/device-handlers.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"device-handlers.js","names":[],"sources":["../../src/handlers/device-handlers.ts"],"sourcesContent":["/**\n * Device Handlers\n * Query handlers for FDA device-related endpoints\n */\n\nimport type {\n  Device510K,\n  DeviceAdverseEvent,\n  DeviceClassification,\n  DeviceEnforcement,\n  FDAToolResponse,\n  SearchParams,\n} from \"../types/fda.js\"\nimport { fdaAPIClient } from \"../utils/api-client.js\"\nimport { loggers } from \"../utils/logger.js\"\n\n// Helper to build date range query\nfunction buildDateQuery(field: string, dateFrom?: string, dateTo?: string): string | undefined {\n  if (!dateFrom && !dateTo) return undefined\n\n  // FDA date format is YYYYMMDD\n  const from = dateFrom?.replace(/-/g, \"\") ?? \"*\"\n  const to = dateTo?.replace(/-/g, \"\") ?? \"*\"\n\n  return `${field}:[${from}+TO+${to}]`\n}\n\n// Helper to escape special characters in search terms\nfunction escapeSearchTerm(term: string): string {\n  return term.replace(/[+\\-&|!(){}[\\]^\"~*?:\\\\]/g, \"\\\\$&\").replace(/\\s+/g, \"+\")\n}\n\n// Helper to build a search query from multiple terms\nfunction buildSearchQuery(terms: Array<{ field: string; value?: string }>): string {\n  const validTerms = terms.filter((t) => t.value !== undefined && t.value.trim() !== \"\")\n  if (validTerms.length === 0) return \"\"\n\n  return validTerms.map((t) => `${t.field}:\"${escapeSearchTerm(t.value!)}\"`).join(\"+AND+\")\n}\n\n// Format truncated text\nfunction truncateText(text: string | undefined, maxLength = 200): string | undefined {\n  if (!text) return undefined\n  return text.length > maxLength ? text.substring(0, maxLength) + \"...\" : text\n}\n\n// Device 510(k) Handler\nexport type Device510KParams = {\n  deviceName?: string\n  applicant?: string\n  productCode?: string\n  clearanceType?: string\n  decisionDateFrom?: string\n  decisionDateTo?: string\n  limit?: number\n  skip?: number\n}\n\ntype FormattedDevice510K = {\n  kNumber: string | undefined\n  deviceName: string | undefined\n  applicant: string | undefined\n  productCode: string | undefined\n  clearanceType: string | undefined\n  decisionCode: string | undefined\n  decisionDescription: string | undefined\n  decisionDate: string | undefined\n  dateReceived: string | undefined\n  city: string | undefined\n  state: string | undefined\n  country: string | undefined\n}\n\nfunction formatDevice510K(device: Device510K): FormattedDevice510K {\n  return {\n    kNumber: device.k_number,\n    deviceName: device.device_name ?? device.openfda?.device_name,\n    applicant: device.applicant,\n    productCode: device.product_code,\n    clearanceType: device.clearance_type,\n    decisionCode: device.decision_code,\n    decisionDescription: device.decision_description,\n    decisionDate: device.decision_date,\n    dateReceived: device.date_received,\n    city: device.city,\n    state: device.state,\n    country: device.country_code,\n  }\n}\n\nexport async function handleSearchDevice510K(\n  params: Device510KParams,\n): Promise<FDAToolResponse<FormattedDevice510K[]>> {\n  loggers.tools(\"searchDevice510K\", params)\n\n  try {\n    const searchTerms: Array<{ field: string; value?: string }> = [\n      { field: \"device_name\", value: params.deviceName },\n      { field: \"applicant\", value: params.applicant },\n      { field: \"product_code\", value: params.productCode },\n      { field: \"clearance_type\", value: params.clearanceType },\n    ]\n\n    const searchQuery = buildSearchQuery(searchTerms)\n    const dateQuery = buildDateQuery(\"decision_date\", params.decisionDateFrom, params.decisionDateTo)\n    const fullQuery = [searchQuery, dateQuery].filter(Boolean).join(\"+AND+\")\n\n    const searchParams: SearchParams = {\n      search: fullQuery || undefined,\n      limit: params.limit,\n      skip: params.skip,\n    }\n\n    const response = await fdaAPIClient.searchDevice510K(searchParams)\n    const results = response.results ?? []\n\n    return {\n      success: true,\n      data: results.map(formatDevice510K),\n      totalResults: response.meta?.results?.total,\n      displayedResults: results.length,\n      searchParams,\n      apiUsage: fdaAPIClient.getRateLimitInfo(),\n    }\n  } catch (error) {\n    return {\n      success: false,\n      error: error instanceof Error ? error.message : String(error),\n    }\n  }\n}\n\n// Device Classification Handler\nexport type DeviceClassificationParams = {\n  deviceName?: string\n  deviceClass?: \"1\" | \"2\" | \"3\"\n  medicalSpecialty?: string\n  productCode?: string\n  regulationNumber?: string\n  limit?: number\n  skip?: number\n}\n\ntype FormattedDeviceClassification = {\n  deviceName: string | undefined\n  deviceClass: string | undefined\n  definition: string | undefined\n  medicalSpecialty: string | undefined\n  medicalSpecialtyDescription: string | undefined\n  productCode: string | undefined\n  regulationNumber: string | undefined\n  gmpExempt: boolean\n  implant: boolean\n  lifeSustaining: boolean\n}\n\nfunction formatDeviceClassification(classification: DeviceClassification): FormattedDeviceClassification {\n  return {\n    deviceName: classification.device_name,\n    deviceClass: classification.device_class,\n    definition: truncateText(classification.definition),\n    medicalSpecialty: classification.medical_specialty,\n    medicalSpecialtyDescription: classification.medical_specialty_description,\n    productCode: classification.product_code,\n    regulationNumber: classification.regulation_number,\n    gmpExempt: classification.gmp_exempt_flag === \"Y\",\n    implant: classification.implant_flag === \"Y\",\n    lifeSustaining: classification.life_sustain_support_flag === \"Y\",\n  }\n}\n\nexport async function handleSearchDeviceClassifications(\n  params: DeviceClassificationParams,\n): Promise<FDAToolResponse<FormattedDeviceClassification[]>> {\n  loggers.tools(\"searchDeviceClassifications\", params)\n\n  try {\n    const searchTerms: Array<{ field: string; value?: string }> = [\n      { field: \"device_name\", value: params.deviceName },\n      { field: \"device_class\", value: params.deviceClass },\n      { field: \"medical_specialty\", value: params.medicalSpecialty },\n      { field: \"product_code\", value: params.productCode },\n      { field: \"regulation_number\", value: params.regulationNumber },\n    ]\n\n    const searchQuery = buildSearchQuery(searchTerms)\n\n    const searchParams: SearchParams = {\n      search: searchQuery || undefined,\n      limit: params.limit,\n      skip: params.skip,\n    }\n\n    const response = await fdaAPIClient.searchDeviceClassifications(searchParams)\n    const results = response.results ?? []\n\n    return {\n      success: true,\n      data: results.map(formatDeviceClassification),\n      totalResults: response.meta?.results?.total,\n      displayedResults: results.length,\n      searchParams,\n      apiUsage: fdaAPIClient.getRateLimitInfo(),\n    }\n  } catch (error) {\n    return {\n      success: false,\n      error: error instanceof Error ? error.message : String(error),\n    }\n  }\n}\n\n// Device Adverse Events (MDR) Handler\nexport type DeviceAdverseEventsParams = {\n  reportNumber?: string\n  deviceName?: string\n  brandName?: string\n  manufacturerName?: string\n  eventType?: \"Injury\" | \"Malfunction\" | \"Death\" | \"Other\"\n  dateFrom?: string\n  dateTo?: string\n  limit?: number\n  skip?: number\n}\n\ntype FormattedDeviceAdverseEvent = {\n  reportNumber: string | undefined\n  dateOfEvent: string | undefined\n  dateReceived: string | undefined\n  eventType: string | undefined\n  adverseEventFlag: boolean\n  productProblemFlag: boolean\n  devices: Array<{\n    brandName: string | undefined\n    genericName: string | undefined\n    manufacturerName: string | undefined\n    modelNumber: string | undefined\n    productCode: string | undefined\n    deviceClass: string | undefined\n  }>\n  mdrText: Array<{\n    textType: string | undefined\n    text: string | undefined\n  }>\n}\n\nfunction formatDeviceAdverseEvent(event: DeviceAdverseEvent): FormattedDeviceAdverseEvent {\n  return {\n    reportNumber: event.report_number,\n    dateOfEvent: event.date_of_event,\n    dateReceived: event.date_received,\n    eventType: event.event_type,\n    adverseEventFlag: event.adverse_event_flag === \"Y\",\n    productProblemFlag: event.product_problem_flag === \"Y\",\n    devices:\n      event.device?.slice(0, 3).map((d) => ({\n        brandName: d.brand_name,\n        genericName: d.generic_name,\n        manufacturerName: d.manufacturer_d_name,\n        modelNumber: d.model_number,\n        productCode: d.device_report_product_code,\n        deviceClass: d.openfda?.device_class,\n      })) ?? [],\n    mdrText:\n      event.mdr_text?.slice(0, 2).map((t) => ({\n        textType: t.text_type_code,\n        text: truncateText(t.text, 300),\n      })) ?? [],\n  }\n}\n\nexport async function handleSearchDeviceAdverseEvents(\n  params: DeviceAdverseEventsParams,\n): Promise<FDAToolResponse<FormattedDeviceAdverseEvent[]>> {\n  loggers.tools(\"searchDeviceAdverseEvents\", params)\n\n  try {\n    // If reportNumber is provided, do a direct lookup\n    if (params.reportNumber) {\n      const searchParams: SearchParams = {\n        search: `report_number:\"${escapeSearchTerm(params.reportNumber)}\"`,\n        limit: 1,\n      }\n\n      const response = await fdaAPIClient.searchDeviceAdverseEvents(searchParams)\n      const results = response.results ?? []\n\n      return {\n        success: true,\n        data: results.map(formatDeviceAdverseEvent),\n        totalResults: response.meta?.results?.total,\n        displayedResults: results.length,\n        searchParams,\n        apiUsage: fdaAPIClient.getRateLimitInfo(),\n      }\n    }\n\n    const searchTerms: Array<{ field: string; value?: string }> = [\n      { field: \"device.generic_name\", value: params.deviceName },\n      { field: \"device.brand_name\", value: params.brandName },\n      { field: \"device.manufacturer_d_name\", value: params.manufacturerName },\n      { field: \"event_type\", value: params.eventType },\n    ]\n\n    const searchQuery = buildSearchQuery(searchTerms)\n    const dateQuery = buildDateQuery(\"date_received\", params.dateFrom, params.dateTo)\n    const fullQuery = [searchQuery, dateQuery].filter(Boolean).join(\"+AND+\")\n\n    const searchParams: SearchParams = {\n      search: fullQuery || undefined,\n      limit: params.limit,\n      skip: params.skip,\n    }\n\n    const response = await fdaAPIClient.searchDeviceAdverseEvents(searchParams)\n    const results = response.results ?? []\n\n    return {\n      success: true,\n      data: results.map(formatDeviceAdverseEvent),\n      totalResults: response.meta?.results?.total,\n      displayedResults: results.length,\n      searchParams,\n      apiUsage: fdaAPIClient.getRateLimitInfo(),\n    }\n  } catch (error) {\n    return {\n      success: false,\n      error: error instanceof Error ? error.message : String(error),\n    }\n  }\n}\n\n// Device Enforcement (Recalls) Handler\nexport type DeviceEnforcementParams = {\n  recallingFirm?: string\n  productDescription?: string\n  classification?: \"Class I\" | \"Class II\" | \"Class III\"\n  status?: \"Ongoing\" | \"Completed\" | \"Terminated\" | \"Pending\"\n  dateFrom?: string\n  dateTo?: string\n  limit?: number\n  skip?: number\n}\n\ntype FormattedDeviceEnforcement = {\n  recallNumber: string | undefined\n  recallingFirm: string | undefined\n  classification: string | undefined\n  status: string | undefined\n  productDescription: string | undefined\n  reasonForRecall: string | undefined\n  recallInitiationDate: string | undefined\n  distributionPattern: string | undefined\n  city: string | undefined\n  state: string | undefined\n  deviceName: string | undefined\n  deviceClass: string | undefined\n}\n\nfunction formatDeviceEnforcement(recall: DeviceEnforcement): FormattedDeviceEnforcement {\n  return {\n    recallNumber: recall.recall_number,\n    recallingFirm: recall.recalling_firm,\n    classification: recall.classification,\n    status: recall.status,\n    productDescription: truncateText(recall.product_description),\n    reasonForRecall: truncateText(recall.reason_for_recall),\n    recallInitiationDate: recall.recall_initiation_date,\n    distributionPattern: truncateText(recall.distribution_pattern),\n    city: recall.city,\n    state: recall.state,\n    deviceName: recall.openfda?.device_name,\n    deviceClass: recall.openfda?.device_class,\n  }\n}\n\nexport async function handleSearchDeviceEnforcement(\n  params: DeviceEnforcementParams,\n): Promise<FDAToolResponse<FormattedDeviceEnforcement[]>> {\n  loggers.tools(\"searchDeviceEnforcement\", params)\n\n  try {\n    const searchTerms: Array<{ field: string; value?: string }> = [\n      { field: \"recalling_firm\", value: params.recallingFirm },\n      { field: \"product_description\", value: params.productDescription },\n      { field: \"classification\", value: params.classification },\n      { field: \"status\", value: params.status },\n    ]\n\n    const searchQuery = buildSearchQuery(searchTerms)\n    const dateQuery = buildDateQuery(\"recall_initiation_date\", params.dateFrom, params.dateTo)\n    const fullQuery = [searchQuery, dateQuery].filter(Boolean).join(\"+AND+\")\n\n    const searchParams: SearchParams = {\n      search: fullQuery || undefined,\n      limit: params.limit,\n      skip: params.skip,\n    }\n\n    const response = await fdaAPIClient.searchDeviceEnforcement(searchParams)\n    const results = response.results ?? []\n\n    return {\n      success: true,\n      data: results.map(formatDeviceEnforcement),\n      totalResults: response.meta?.results?.total,\n      displayedResults: results.length,\n      searchParams,\n      apiUsage: fdaAPIClient.getRateLimitInfo(),\n    }\n  } catch (error) {\n    return {\n      success: false,\n      error: error instanceof Error ? error.message : String(error),\n    }\n  }\n}\n"],"mappings":"mGAiBA,SAAS,EAAe,EAAe,EAAmB,EAAqC,CACzF,MAAC,GAAY,CAAC,GAMlB,MAAO,GAAG,EAAM,IAHH,GAAU,QAAQ,KAAM,GAAG,EAAI,IAGnB,MAFd,GAAQ,QAAQ,KAAM,GAAG,EAAI,IAEN,GAIpC,SAAS,EAAiB,EAAsB,CAC9C,OAAO,EAAK,QAAQ,2BAA4B,OAAO,CAAC,QAAQ,OAAQ,IAAI,CAI9E,SAAS,EAAiB,EAAyD,CACjF,IAAM,EAAa,EAAM,OAAQ,GAAM,EAAE,QAAU,IAAA,IAAa,EAAE,MAAM,MAAM,GAAK,GAAG,CAGtF,OAFI,EAAW,SAAW,EAAU,GAE7B,EAAW,IAAK,GAAM,GAAG,EAAE,MAAM,IAAI,EAAiB,EAAE,MAAO,CAAC,GAAG,CAAC,KAAK,QAAQ,CAI1F,SAAS,EAAa,EAA0B,EAAY,IAAyB,CAC9E,KACL,OAAO,EAAK,OAAS,EAAY,EAAK,UAAU,EAAG,EAAU,CAAG,MAAQ,EA8B1E,SAAS,EAAiB,EAAyC,CACjE,MAAO,CACL,QAAS,EAAO,SAChB,WAAY,EAAO,aAAe,EAAO,SAAS,YAClD,UAAW,EAAO,UAClB,YAAa,EAAO,aACpB,cAAe,EAAO,eACtB,aAAc,EAAO,cACrB,oBAAqB,EAAO,qBAC5B,aAAc,EAAO,cACrB,aAAc,EAAO,cACrB,KAAM,EAAO,KACb,MAAO,EAAO,MACd,QAAS,EAAO,aACjB,CAGH,eAAsB,EACpB,EACiD,CACjD,EAAQ,MAAM,mBAAoB,EAAO,CAEzC,GAAI,CAYF,IAAM,EAA6B,CACjC,OAHgB,CAFE,EAP0C,CAC5D,CAAE,MAAO,cAAe,MAAO,EAAO,WAAY,CAClD,CAAE,MAAO,YAAa,MAAO,EAAO,UAAW,CAC/C,CAAE,MAAO,eAAgB,MAAO,EAAO,YAAa,CACpD,CAAE,MAAO,iBAAkB,MAAO,EAAO,cAAe,CACzD,CAEgD,CAC/B,EAAe,gBAAiB,EAAO,iBAAkB,EAAO,eAAe,CACvD,CAAC,OAAO,QAAQ,CAAC,KAAK,QAAQ,EAGjD,IAAA,GACrB,MAAO,EAAO,MACd,KAAM,EAAO,KACd,CAEK,EAAW,MAAM,EAAa,iBAAiB,EAAa,CAC5D,EAAU,EAAS,SAAW,EAAE,CAEtC,MAAO,CACL,QAAS,GACT,KAAM,EAAQ,IAAI,EAAiB,CACnC,aAAc,EAAS,MAAM,SAAS,MACtC,iBAAkB,EAAQ,OAC1B,eACA,SAAU,EAAa,kBAAkB,CAC1C,OACM,EAAO,CACd,MAAO,CACL,QAAS,GACT,MAAO,aAAiB,MAAQ,EAAM,QAAU,OAAO,EAAM,CAC9D,EA4BL,SAAS,EAA2B,EAAqE,CACvG,MAAO,CACL,WAAY,EAAe,YAC3B,YAAa,EAAe,aAC5B,WAAY,EAAa,EAAe,WAAW,CACnD,iBAAkB,EAAe,kBACjC,4BAA6B,EAAe,8BAC5C,YAAa,EAAe,aAC5B,iBAAkB,EAAe,kBACjC,UAAW,EAAe,kBAAoB,IAC9C,QAAS,EAAe,eAAiB,IACzC,eAAgB,EAAe,4BAA8B,IAC9D,CAGH,eAAsB,EACpB,EAC2D,CAC3D,EAAQ,MAAM,8BAA+B,EAAO,CAEpD,GAAI,CAWF,IAAM,EAA6B,CACjC,OAHkB,EAR0C,CAC5D,CAAE,MAAO,cAAe,MAAO,EAAO,WAAY,CAClD,CAAE,MAAO,eAAgB,MAAO,EAAO,YAAa,CACpD,CAAE,MAAO,oBAAqB,MAAO,EAAO,iBAAkB,CAC9D,CAAE,MAAO,eAAgB,MAAO,EAAO,YAAa,CACpD,CAAE,MAAO,oBAAqB,MAAO,EAAO,iBAAkB,CAC/D,CAEgD,EAGxB,IAAA,GACvB,MAAO,EAAO,MACd,KAAM,EAAO,KACd,CAEK,EAAW,MAAM,EAAa,4BAA4B,EAAa,CACvE,EAAU,EAAS,SAAW,EAAE,CAEtC,MAAO,CACL,QAAS,GACT,KAAM,EAAQ,IAAI,EAA2B,CAC7C,aAAc,EAAS,MAAM,SAAS,MACtC,iBAAkB,EAAQ,OAC1B,eACA,SAAU,EAAa,kBAAkB,CAC1C,OACM,EAAO,CACd,MAAO,CACL,QAAS,GACT,MAAO,aAAiB,MAAQ,EAAM,QAAU,OAAO,EAAM,CAC9D,EAsCL,SAAS,EAAyB,EAAwD,CACxF,MAAO,CACL,aAAc,EAAM,cACpB,YAAa,EAAM,cACnB,aAAc,EAAM,cACpB,UAAW,EAAM,WACjB,iBAAkB,EAAM,qBAAuB,IAC/C,mBAAoB,EAAM,uBAAyB,IACnD,QACE,EAAM,QAAQ,MAAM,EAAG,EAAE,CAAC,IAAK,IAAO,CACpC,UAAW,EAAE,WACb,YAAa,EAAE,aACf,iBAAkB,EAAE,oBACpB,YAAa,EAAE,aACf,YAAa,EAAE,2BACf,YAAa,EAAE,SAAS,aACzB,EAAE,EAAI,EAAE,CACX,QACE,EAAM,UAAU,MAAM,EAAG,EAAE,CAAC,IAAK,IAAO,CACtC,SAAU,EAAE,eACZ,KAAM,EAAa,EAAE,KAAM,IAAI,CAChC,EAAE,EAAI,EAAE,CACZ,CAGH,eAAsB,EACpB,EACyD,CACzD,EAAQ,MAAM,4BAA6B,EAAO,CAElD,GAAI,CAEF,GAAI,EAAO,aAAc,CACvB,IAAM,EAA6B,CACjC,OAAQ,kBAAkB,EAAiB,EAAO,aAAa,CAAC,GAChE,MAAO,EACR,CAEK,EAAW,MAAM,EAAa,0BAA0B,EAAa,CACrE,EAAU,EAAS,SAAW,EAAE,CAEtC,MAAO,CACL,QAAS,GACT,KAAM,EAAQ,IAAI,EAAyB,CAC3C,aAAc,EAAS,MAAM,SAAS,MACtC,iBAAkB,EAAQ,OAC1B,eACA,SAAU,EAAa,kBAAkB,CAC1C,CAcH,IAAM,EAA6B,CACjC,OAHgB,CAFE,EAP0C,CAC5D,CAAE,MAAO,sBAAuB,MAAO,EAAO,WAAY,CAC1D,CAAE,MAAO,oBAAqB,MAAO,EAAO,UAAW,CACvD,CAAE,MAAO,6BAA8B,MAAO,EAAO,iBAAkB,CACvE,CAAE,MAAO,aAAc,MAAO,EAAO,UAAW,CACjD,CAEgD,CAC/B,EAAe,gBAAiB,EAAO,SAAU,EAAO,OAAO,CACvC,CAAC,OAAO,QAAQ,CAAC,KAAK,QAAQ,EAGjD,IAAA,GACrB,MAAO,EAAO,MACd,KAAM,EAAO,KACd,CAEK,EAAW,MAAM,EAAa,0BAA0B,EAAa,CACrE,EAAU,EAAS,SAAW,EAAE,CAEtC,MAAO,CACL,QAAS,GACT,KAAM,EAAQ,IAAI,EAAyB,CAC3C,aAAc,EAAS,MAAM,SAAS,MACtC,iBAAkB,EAAQ,OAC1B,eACA,SAAU,EAAa,kBAAkB,CAC1C,OACM,EAAO,CACd,MAAO,CACL,QAAS,GACT,MAAO,aAAiB,MAAQ,EAAM,QAAU,OAAO,EAAM,CAC9D,EA+BL,SAAS,EAAwB,EAAuD,CACtF,MAAO,CACL,aAAc,EAAO,cACrB,cAAe,EAAO,eACtB,eAAgB,EAAO,eACvB,OAAQ,EAAO,OACf,mBAAoB,EAAa,EAAO,oBAAoB,CAC5D,gBAAiB,EAAa,EAAO,kBAAkB,CACvD,qBAAsB,EAAO,uBAC7B,oBAAqB,EAAa,EAAO,qBAAqB,CAC9D,KAAM,EAAO,KACb,MAAO,EAAO,MACd,WAAY,EAAO,SAAS,YAC5B,YAAa,EAAO,SAAS,aAC9B,CAGH,eAAsB,EACpB,EACwD,CACxD,EAAQ,MAAM,0BAA2B,EAAO,CAEhD,GAAI,CAYF,IAAM,EAA6B,CACjC,OAHgB,CAFE,EAP0C,CAC5D,CAAE,MAAO,iBAAkB,MAAO,EAAO,cAAe,CACxD,CAAE,MAAO,sBAAuB,MAAO,EAAO,mBAAoB,CAClE,CAAE,MAAO,iBAAkB,MAAO,EAAO,eAAgB,CACzD,CAAE,MAAO,SAAU,MAAO,EAAO,OAAQ,CAC1C,CAEgD,CAC/B,EAAe,yBAA0B,EAAO,SAAU,EAAO,OAAO,CAChD,CAAC,OAAO,QAAQ,CAAC,KAAK,QAAQ,EAGjD,IAAA,GACrB,MAAO,EAAO,MACd,KAAM,EAAO,KACd,CAEK,EAAW,MAAM,EAAa,wBAAwB,EAAa,CACnE,EAAU,EAAS,SAAW,EAAE,CAEtC,MAAO,CACL,QAAS,GACT,KAAM,EAAQ,IAAI,EAAwB,CAC1C,aAAc,EAAS,MAAM,SAAS,MACtC,iBAAkB,EAAQ,OAC1B,eACA,SAAU,EAAa,kBAAkB,CAC1C,OACM,EAAO,CACd,MAAO,CACL,QAAS,GACT,MAAO,aAAiB,MAAQ,EAAM,QAAU,OAAO,EAAM,CAC9D"}

package/dist/handlers/drug-handlers.d.ts

@@ -1,8 +1,8 @@
 import { FDAToolResponse } from "../types/fda.js";
 
 //#region src/handlers/drug-handlers.d.ts
-
 type DrugAdverseEventsParams = {
+  safetyReportId?: string;
   drugName?: string;
   reaction?: string;
   manufacturer?: string;
@@ -33,21 +33,36 @@ type FormattedDrugAdverseEvent = {
 };
 declare function handleSearchDrugAdverseEvents(params: DrugAdverseEventsParams): Promise<FDAToolResponse<FormattedDrugAdverseEvent[]>>;
 type DrugLabelsParams = {
+  setId?: string;
   drugName?: string;
   indication?: string;
   activeIngredient?: string;
   route?: string;
+  hasBoxedWarning?: boolean;
+  sections?: string[];
   limit?: number;
   skip?: number;
 };
 type FormattedDrugLabel = {
+  setId: string | undefined;
   brandName: string | undefined;
   genericName: string | undefined;
   manufacturer: string | undefined;
   activeIngredients: string[];
+  boxedWarning: string | undefined;
   indications: string | undefined;
   warnings: string | undefined;
+  contraindications: string | undefined;
+  adverseReactions: string | undefined;
+  drugInteractions: string | undefined;
   dosageAndAdministration: string | undefined;
+  clinicalPharmacology: string | undefined;
+  mechanismOfAction: string | undefined;
+  pharmacokinetics: string | undefined;
+  overdosage: string | undefined;
+  description: string | undefined;
+  howSupplied: string | undefined;
+  storageAndHandling: string | undefined;
   route: string[];
 };
 declare function handleSearchDrugLabels(params: DrugLabelsParams): Promise<FDAToolResponse<FormattedDrugLabel[]>>;

package/dist/handlers/drug-handlers.js

@@ -1 +1,2 @@
-import"../utils/logger.js";import"../api-client-BGnUXMwX.js";import{a as e,i as t,n,o as r,r as i,t as a}from"../drug-handlers-Fz_6NLl5.js";export{a as handleSearchDrugAdverseEvents,n as handleSearchDrugEnforcement,i as handleSearchDrugLabels,t as handleSearchDrugNDC,e as handleSearchDrugShortages,r as handleSearchDrugsFDA};
+import{loggers as e}from"../utils/logger.js";import{fdaAPIClient as t}from"../utils/api-client.js";function n(e,t,n){if(!(!t&&!n))return`${e}:[${t?.replace(/-/g,``)??`*`}+TO+${n?.replace(/-/g,``)??`*`}]`}function r(e){return e.replace(/[+\-&|!(){}[\]^"~*?:\\]/g,`\\$&`).replace(/\s+/g,`+`)}function i(e){let t=e.filter(e=>e.value!==void 0&&e.value.trim()!==``);return t.length===0?``:t.map(e=>`${e.field}:"${r(e.value)}"`).join(`+AND+`)}function a(e,t=200){if(e)return e.length>t?e.substring(0,t)+`...`:e}function o(e){return{reportId:e.safetyreportid,receiveDate:e.receivedate,serious:e.serious===`1`,drugs:e.patient?.drug?.slice(0,3).map(e=>({name:e.medicinalproduct??e.activesubstance?.activesubstancename,indication:e.drugindication,route:e.drugadministrationroute}))??[],reactions:e.patient?.reaction?.slice(0,3).map(e=>({reaction:e.reactionmeddrapt,outcome:e.reactionoutcome}))??[],patient:{age:e.patient?.patientonsetage?`${e.patient.patientonsetage} ${e.patient.patientonsetageunit??``}`:void 0,sex:e.patient?.patientsex===`1`?`Male`:e.patient?.patientsex===`2`?`Female`:void 0,weight:e.patient?.patientweight?`${e.patient.patientweight} kg`:void 0}}}async function s(a){e.tools(`searchDrugAdverseEvents`,a);try{if(a.safetyReportId){let e={search:`safetyreportid:"${r(a.safetyReportId)}"`,limit:1},n=await t.searchDrugAdverseEvents(e),i=n.results??[];return{success:!0,data:i.map(o),totalResults:n.meta?.results?.total,displayedResults:i.length,searchParams:e,apiUsage:t.getRateLimitInfo()}}let e=[{field:`patient.drug.medicinalproduct`,value:a.drugName},{field:`patient.reaction.reactionmeddrapt`,value:a.reaction},{field:`patient.drug.openfda.manufacturer_name`,value:a.manufacturer}];a.serious!==void 0&&e.push({field:`serious`,value:a.serious?`1`:`2`});let s={search:[i(e),n(`receivedate`,a.dateFrom,a.dateTo)].filter(Boolean).join(`+AND+`)||void 0,limit:a.limit,skip:a.skip},c=await t.searchDrugAdverseEvents(s),l=c.results??[];return{success:!0,data:l.map(o),totalResults:c.meta?.results?.total,displayedResults:l.length,searchParams:s,apiUsage:t.getRateLimitInfo()}}catch(e){return{success:!1,error:e instanceof Error?e.message:String(e)}}}function c(e,t){let n=e=>!t||t.includes(e);return{setId:e.set_id,brandName:e.openfda?.brand_name?.[0],genericName:e.openfda?.generic_name?.[0],manufacturer:e.openfda?.manufacturer_name?.[0],activeIngredients:e.openfda?.substance_name?.slice(0,5)??[],boxedWarning:n(`boxed_warning`)?a(e.boxed_warning?.[0],500):void 0,indications:n(`indications_and_usage`)?a(e.indications_and_usage?.[0]):void 0,warnings:n(`warnings`)?a(e.warnings?.[0]):void 0,contraindications:n(`contraindications`)?a(e.contraindications?.[0]):void 0,adverseReactions:n(`adverse_reactions`)?a(e.adverse_reactions?.[0]):void 0,drugInteractions:n(`drug_interactions`)?a(e.drug_interactions?.[0]):void 0,dosageAndAdministration:n(`dosage_and_administration`)?a(e.dosage_and_administration?.[0]):void 0,clinicalPharmacology:n(`clinical_pharmacology`)?a(e.clinical_pharmacology?.[0]):void 0,mechanismOfAction:n(`mechanism_of_action`)?a(e.mechanism_of_action?.[0]):void 0,pharmacokinetics:n(`pharmacokinetics`)?a(e.pharmacokinetics?.[0]):void 0,overdosage:n(`overdosage`)?a(e.overdosage?.[0]):void 0,description:n(`description`)?a(e.description?.[0]):void 0,howSupplied:n(`how_supplied`)?a(e.how_supplied?.[0]):void 0,storageAndHandling:n(`storage_and_handling`)?a(e.storage_and_handling?.[0]):void 0,route:e.openfda?.route?.slice(0,3)??[]}}async function l(n){e.tools(`searchDrugLabels`,n);try{if(n.setId){let e={search:`set_id:"${r(n.setId)}"`,limit:1},i=await t.searchDrugLabels(e),a=i.results??[];return{success:!0,data:a.map(e=>c(e,n.sections)),totalResults:i.meta?.results?.total,displayedResults:a.length,searchParams:e,apiUsage:t.getRateLimitInfo()}}let e={search:[i([{field:`openfda.brand_name`,value:n.drugName},{field:`indications_and_usage`,value:n.indication},{field:`openfda.substance_name`,value:n.activeIngredient},{field:`openfda.route`,value:n.route}]),n.hasBoxedWarning?`_exists_:boxed_warning`:void 0].filter(Boolean).join(`+AND+`)||void 0,limit:n.limit,skip:n.skip},a=await t.searchDrugLabels(e),o=a.results??[];return{success:!0,data:o.map(e=>c(e,n.sections)),totalResults:a.meta?.results?.total,displayedResults:o.length,searchParams:e,apiUsage:t.getRateLimitInfo()}}catch(e){return{success:!1,error:e instanceof Error?e.message:String(e)}}}function u(e){return{productNdc:e.product_ndc,brandName:e.brand_name,genericName:e.generic_name,labelerName:e.labeler_name,dosageForm:e.dosage_form,route:e.route??[],activeIngredients:e.active_ingredients?.slice(0,3).map(e=>({name:e.name,strength:e.strength}))??[],marketingStartDate:e.marketing_start_date,productType:e.product_type}}async function d(n){e.tools(`searchDrugNDC`,n);try{let e={search:i([{field:`product_ndc`,value:n.productNdc},{field:`brand_name`,value:n.brandName},{field:`generic_name`,value:n.genericName},{field:`labeler_name`,value:n.labelerName},{field:`dosage_form`,value:n.dosageForm},{field:`route`,value:n.route}])||void 0,limit:n.limit,skip:n.skip},r=await t.searchDrugNDC(e),a=r.results??[];return{success:!0,data:a.map(u),totalResults:r.meta?.results?.total,displayedResults:a.length,searchParams:e,apiUsage:t.getRateLimitInfo()}}catch(e){return{success:!1,error:e instanceof Error?e.message:String(e)}}}function f(e){return{recallNumber:e.recall_number,recallingFirm:e.recalling_firm,classification:e.classification,status:e.status,productDescription:a(e.product_description),reasonForRecall:a(e.reason_for_recall),recallInitiationDate:e.recall_initiation_date,distributionPattern:a(e.distribution_pattern),city:e.city,state:e.state}}async function p(r){e.tools(`searchDrugEnforcement`,r);try{let e={search:[i([{field:`recalling_firm`,value:r.recallingFirm},{field:`classification`,value:r.classification},{field:`status`,value:r.status},{field:`state`,value:r.state}]),n(`recall_initiation_date`,r.dateFrom,r.dateTo)].filter(Boolean).join(`+AND+`)||void 0,limit:r.limit,skip:r.skip},a=await t.searchDrugEnforcement(e),o=a.results??[];return{success:!0,data:o.map(f),totalResults:a.meta?.results?.total,displayedResults:o.length,searchParams:e,apiUsage:t.getRateLimitInfo()}}catch(e){return{success:!1,error:e instanceof Error?e.message:String(e)}}}function m(e){let t=e.submissions?.[0];return{applicationNumber:e.application_number,sponsorName:e.sponsor_name,products:e.products?.slice(0,3).map(e=>({brandName:e.brand_name,dosageForm:e.dosage_form,route:e.route,marketingStatus:e.marketing_status,activeIngredients:e.active_ingredients?.slice(0,3).map(e=>({name:e.name,strength:e.strength}))??[]}))??[],latestSubmission:t?{type:t.submission_type,status:t.submission_status,statusDate:t.submission_status_date}:void 0}}async function h(n){e.tools(`searchDrugsFDA`,n);try{let e={search:i([{field:`sponsor_name`,value:n.sponsorName},{field:`application_number`,value:n.applicationNumber},{field:`products.brand_name`,value:n.brandName},{field:`products.marketing_status`,value:n.marketingStatus}])||void 0,limit:n.limit,skip:n.skip},r=await t.searchDrugsFDA(e),a=r.results??[];return{success:!0,data:a.map(m),totalResults:r.meta?.results?.total,displayedResults:a.length,searchParams:e,apiUsage:t.getRateLimitInfo()}}catch(e){return{success:!1,error:e instanceof Error?e.message:String(e)}}}function g(e){return{genericName:e.generic_name,proprietaryName:e.proprietary_name,status:e.status,description:a(e.description),initialPostingDate:e.initial_posting_date,resolvedShortageDate:e.resolved_shortage_date}}async function _(n){e.tools(`searchDrugShortages`,n);try{let e={search:i([{field:`generic_name`,value:n.genericName},{field:`status`,value:n.status}])||void 0,limit:n.limit,skip:n.skip},r=await t.searchDrugShortages(e),a=r.results??[];return{success:!0,data:a.map(g),totalResults:r.meta?.results?.total,displayedResults:a.length,searchParams:e,apiUsage:t.getRateLimitInfo()}}catch(e){return{success:!1,error:e instanceof Error?e.message:String(e)}}}export{s as handleSearchDrugAdverseEvents,p as handleSearchDrugEnforcement,l as handleSearchDrugLabels,d as handleSearchDrugNDC,_ as handleSearchDrugShortages,h as handleSearchDrugsFDA};
+//# sourceMappingURL=drug-handlers.js.map

package/dist/handlers/drug-handlers.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"drug-handlers.js","names":[],"sources":["../../src/handlers/drug-handlers.ts"],"sourcesContent":["/**\n * Drug Handlers\n * Query handlers for FDA drug-related endpoints\n */\n\nimport type {\n  DrugAdverseEvent,\n  DrugEnforcement,\n  DrugLabel,\n  DrugNDC,\n  DrugsFDA,\n  DrugShortage,\n  FDAToolResponse,\n  SearchParams,\n} from \"../types/fda.js\"\nimport { fdaAPIClient } from \"../utils/api-client.js\"\nimport { loggers } from \"../utils/logger.js\"\n\n// Helper to build date range query\nfunction buildDateQuery(field: string, dateFrom?: string, dateTo?: string): string | undefined {\n  if (!dateFrom && !dateTo) return undefined\n\n  // FDA date format is YYYYMMDD\n  const from = dateFrom?.replace(/-/g, \"\") ?? \"*\"\n  const to = dateTo?.replace(/-/g, \"\") ?? \"*\"\n\n  return `${field}:[${from}+TO+${to}]`\n}\n\n// Helper to escape special characters in search terms\nfunction escapeSearchTerm(term: string): string {\n  // Escape special characters that have meaning in FDA's search syntax\n  return term.replace(/[+\\-&|!(){}[\\]^\"~*?:\\\\]/g, \"\\\\$&\").replace(/\\s+/g, \"+\")\n}\n\n// Helper to build a search query from multiple terms\nfunction buildSearchQuery(terms: Array<{ field: string; value?: string }>): string {\n  const validTerms = terms.filter((t) => t.value !== undefined && t.value.trim() !== \"\")\n  if (validTerms.length === 0) return \"\"\n\n  return validTerms.map((t) => `${t.field}:\"${escapeSearchTerm(t.value!)}\"`).join(\"+AND+\")\n}\n\n// Format truncated text\nfunction truncateText(text: string | undefined, maxLength = 200): string | undefined {\n  if (!text) return undefined\n  return text.length > maxLength ? text.substring(0, maxLength) + \"...\" : text\n}\n\n// Drug Adverse Events Handler\nexport type DrugAdverseEventsParams = {\n  safetyReportId?: string\n  drugName?: string\n  reaction?: string\n  manufacturer?: string\n  serious?: boolean\n  dateFrom?: string\n  dateTo?: string\n  limit?: number\n  skip?: number\n}\n\ntype FormattedDrugAdverseEvent = {\n  reportId: string | undefined\n  receiveDate: string | undefined\n  serious: boolean\n  drugs: Array<{\n    name: string | undefined\n    indication: string | undefined\n    route: string | undefined\n  }>\n  reactions: Array<{\n    reaction: string | undefined\n    outcome: string | undefined\n  }>\n  patient: {\n    age: string | undefined\n    sex: string | undefined\n    weight: string | undefined\n  }\n}\n\nfunction formatDrugAdverseEvent(event: DrugAdverseEvent): FormattedDrugAdverseEvent {\n  return {\n    reportId: event.safetyreportid,\n    receiveDate: event.receivedate,\n    serious: event.serious === \"1\",\n    drugs:\n      event.patient?.drug?.slice(0, 3).map((d) => ({\n        name: d.medicinalproduct ?? d.activesubstance?.activesubstancename,\n        indication: d.drugindication,\n        route: d.drugadministrationroute,\n      })) ?? [],\n    reactions:\n      event.patient?.reaction?.slice(0, 3).map((r) => ({\n        reaction: r.reactionmeddrapt,\n        outcome: r.reactionoutcome,\n      })) ?? [],\n    patient: {\n      age: event.patient?.patientonsetage\n        ? `${event.patient.patientonsetage} ${event.patient.patientonsetageunit ?? \"\"}`\n        : undefined,\n      sex: event.patient?.patientsex === \"1\" ? \"Male\" : event.patient?.patientsex === \"2\" ? \"Female\" : undefined,\n      weight: event.patient?.patientweight ? `${event.patient.patientweight} kg` : undefined,\n    },\n  }\n}\n\nexport async function handleSearchDrugAdverseEvents(\n  params: DrugAdverseEventsParams,\n): Promise<FDAToolResponse<FormattedDrugAdverseEvent[]>> {\n  loggers.tools(\"searchDrugAdverseEvents\", params)\n\n  try {\n    // If safetyReportId is provided, do a direct lookup\n    if (params.safetyReportId) {\n      const searchParams: SearchParams = {\n        search: `safetyreportid:\"${escapeSearchTerm(params.safetyReportId)}\"`,\n        limit: 1,\n      }\n\n      const response = await fdaAPIClient.searchDrugAdverseEvents(searchParams)\n      const results = response.results ?? []\n\n      return {\n        success: true,\n        data: results.map(formatDrugAdverseEvent),\n        totalResults: response.meta?.results?.total,\n        displayedResults: results.length,\n        searchParams,\n        apiUsage: fdaAPIClient.getRateLimitInfo(),\n      }\n    }\n\n    const searchTerms: Array<{ field: string; value?: string }> = [\n      { field: \"patient.drug.medicinalproduct\", value: params.drugName },\n      { field: \"patient.reaction.reactionmeddrapt\", value: params.reaction },\n      { field: \"patient.drug.openfda.manufacturer_name\", value: params.manufacturer },\n    ]\n\n    if (params.serious !== undefined) {\n      searchTerms.push({ field: \"serious\", value: params.serious ? \"1\" : \"2\" })\n    }\n\n    const searchQuery = buildSearchQuery(searchTerms)\n    const dateQuery = buildDateQuery(\"receivedate\", params.dateFrom, params.dateTo)\n    const fullQuery = [searchQuery, dateQuery].filter(Boolean).join(\"+AND+\")\n\n    const searchParams: SearchParams = {\n      search: fullQuery || undefined,\n      limit: params.limit,\n      skip: params.skip,\n    }\n\n    const response = await fdaAPIClient.searchDrugAdverseEvents(searchParams)\n    const results = response.results ?? []\n\n    return {\n      success: true,\n      data: results.map(formatDrugAdverseEvent),\n      totalResults: response.meta?.results?.total,\n      displayedResults: results.length,\n      searchParams,\n      apiUsage: fdaAPIClient.getRateLimitInfo(),\n    }\n  } catch (error) {\n    return {\n      success: false,\n      error: error instanceof Error ? error.message : String(error),\n    }\n  }\n}\n\n// Drug Labels Handler\nexport type DrugLabelsParams = {\n  setId?: string\n  drugName?: string\n  indication?: string\n  activeIngredient?: string\n  route?: string\n  hasBoxedWarning?: boolean\n  sections?: string[]\n  limit?: number\n  skip?: number\n}\n\ntype FormattedDrugLabel = {\n  setId: string | undefined\n  brandName: string | undefined\n  genericName: string | undefined\n  manufacturer: string | undefined\n  activeIngredients: string[]\n  boxedWarning: string | undefined\n  indications: string | undefined\n  warnings: string | undefined\n  contraindications: string | undefined\n  adverseReactions: string | undefined\n  drugInteractions: string | undefined\n  dosageAndAdministration: string | undefined\n  clinicalPharmacology: string | undefined\n  mechanismOfAction: string | undefined\n  pharmacokinetics: string | undefined\n  overdosage: string | undefined\n  description: string | undefined\n  howSupplied: string | undefined\n  storageAndHandling: string | undefined\n  route: string[]\n}\n\nfunction formatDrugLabel(label: DrugLabel, sections?: string[]): FormattedDrugLabel {\n  // Helper to conditionally include section based on sections filter\n  const includeSection = (sectionName: string) => !sections || sections.includes(sectionName)\n\n  return {\n    setId: label.set_id,\n    brandName: label.openfda?.brand_name?.[0],\n    genericName: label.openfda?.generic_name?.[0],\n    manufacturer: label.openfda?.manufacturer_name?.[0],\n    activeIngredients: label.openfda?.substance_name?.slice(0, 5) ?? [],\n    boxedWarning: includeSection(\"boxed_warning\") ? truncateText(label.boxed_warning?.[0], 500) : undefined,\n    indications: includeSection(\"indications_and_usage\") ? truncateText(label.indications_and_usage?.[0]) : undefined,\n    warnings: includeSection(\"warnings\") ? truncateText(label.warnings?.[0]) : undefined,\n    contraindications: includeSection(\"contraindications\") ? truncateText(label.contraindications?.[0]) : undefined,\n    adverseReactions: includeSection(\"adverse_reactions\") ? truncateText(label.adverse_reactions?.[0]) : undefined,\n    drugInteractions: includeSection(\"drug_interactions\") ? truncateText(label.drug_interactions?.[0]) : undefined,\n    dosageAndAdministration: includeSection(\"dosage_and_administration\")\n      ? truncateText(label.dosage_and_administration?.[0])\n      : undefined,\n    clinicalPharmacology: includeSection(\"clinical_pharmacology\")\n      ? truncateText(label.clinical_pharmacology?.[0])\n      : undefined,\n    mechanismOfAction: includeSection(\"mechanism_of_action\") ? truncateText(label.mechanism_of_action?.[0]) : undefined,\n    pharmacokinetics: includeSection(\"pharmacokinetics\") ? truncateText(label.pharmacokinetics?.[0]) : undefined,\n    overdosage: includeSection(\"overdosage\") ? truncateText(label.overdosage?.[0]) : undefined,\n    description: includeSection(\"description\") ? truncateText(label.description?.[0]) : undefined,\n    howSupplied: includeSection(\"how_supplied\") ? truncateText(label.how_supplied?.[0]) : undefined,\n    storageAndHandling: includeSection(\"storage_and_handling\")\n      ? truncateText(label.storage_and_handling?.[0])\n      : undefined,\n    route: label.openfda?.route?.slice(0, 3) ?? [],\n  }\n}\n\nexport async function handleSearchDrugLabels(params: DrugLabelsParams): Promise<FDAToolResponse<FormattedDrugLabel[]>> {\n  loggers.tools(\"searchDrugLabels\", params)\n\n  try {\n    // If setId is provided, do a direct lookup\n    if (params.setId) {\n      const searchParams: SearchParams = {\n        search: `set_id:\"${escapeSearchTerm(params.setId)}\"`,\n        limit: 1,\n      }\n\n      const response = await fdaAPIClient.searchDrugLabels(searchParams)\n      const results = response.results ?? []\n\n      return {\n        success: true,\n        data: results.map((label) => formatDrugLabel(label, params.sections)),\n        totalResults: response.meta?.results?.total,\n        displayedResults: results.length,\n        searchParams,\n        apiUsage: fdaAPIClient.getRateLimitInfo(),\n      }\n    }\n\n    const searchTerms: Array<{ field: string; value?: string }> = [\n      { field: \"openfda.brand_name\", value: params.drugName },\n      { field: \"indications_and_usage\", value: params.indication },\n      { field: \"openfda.substance_name\", value: params.activeIngredient },\n      { field: \"openfda.route\", value: params.route },\n    ]\n\n    const searchQuery = buildSearchQuery(searchTerms)\n\n    // Build boxed warning existence query\n    const boxedWarningQuery = params.hasBoxedWarning ? \"_exists_:boxed_warning\" : undefined\n\n    const fullQuery = [searchQuery, boxedWarningQuery].filter(Boolean).join(\"+AND+\")\n\n    const searchParams: SearchParams = {\n      search: fullQuery || undefined,\n      limit: params.limit,\n      skip: params.skip,\n    }\n\n    const response = await fdaAPIClient.searchDrugLabels(searchParams)\n    const results = response.results ?? []\n\n    return {\n      success: true,\n      data: results.map((label) => formatDrugLabel(label, params.sections)),\n      totalResults: response.meta?.results?.total,\n      displayedResults: results.length,\n      searchParams,\n      apiUsage: fdaAPIClient.getRateLimitInfo(),\n    }\n  } catch (error) {\n    return {\n      success: false,\n      error: error instanceof Error ? error.message : String(error),\n    }\n  }\n}\n\n// Drug NDC Handler\nexport type DrugNDCParams = {\n  productNdc?: string\n  brandName?: string\n  genericName?: string\n  labelerName?: string\n  dosageForm?: string\n  route?: string\n  limit?: number\n  skip?: number\n}\n\ntype FormattedDrugNDC = {\n  productNdc: string | undefined\n  brandName: string | undefined\n  genericName: string | undefined\n  labelerName: string | undefined\n  dosageForm: string | undefined\n  route: string[]\n  activeIngredients: Array<{ name: string | undefined; strength: string | undefined }>\n  marketingStartDate: string | undefined\n  productType: string | undefined\n}\n\nfunction formatDrugNDC(ndc: DrugNDC): FormattedDrugNDC {\n  return {\n    productNdc: ndc.product_ndc,\n    brandName: ndc.brand_name,\n    genericName: ndc.generic_name,\n    labelerName: ndc.labeler_name,\n    dosageForm: ndc.dosage_form,\n    route: ndc.route ?? [],\n    activeIngredients:\n      ndc.active_ingredients?.slice(0, 3).map((ai) => ({\n        name: ai.name,\n        strength: ai.strength,\n      })) ?? [],\n    marketingStartDate: ndc.marketing_start_date,\n    productType: ndc.product_type,\n  }\n}\n\nexport async function handleSearchDrugNDC(params: DrugNDCParams): Promise<FDAToolResponse<FormattedDrugNDC[]>> {\n  loggers.tools(\"searchDrugNDC\", params)\n\n  try {\n    const searchTerms: Array<{ field: string; value?: string }> = [\n      { field: \"product_ndc\", value: params.productNdc },\n      { field: \"brand_name\", value: params.brandName },\n      { field: \"generic_name\", value: params.genericName },\n      { field: \"labeler_name\", value: params.labelerName },\n      { field: \"dosage_form\", value: params.dosageForm },\n      { field: \"route\", value: params.route },\n    ]\n\n    const searchQuery = buildSearchQuery(searchTerms)\n\n    const searchParams: SearchParams = {\n      search: searchQuery || undefined,\n      limit: params.limit,\n      skip: params.skip,\n    }\n\n    const response = await fdaAPIClient.searchDrugNDC(searchParams)\n    const results = response.results ?? []\n\n    return {\n      success: true,\n      data: results.map(formatDrugNDC),\n      totalResults: response.meta?.results?.total,\n      displayedResults: results.length,\n      searchParams,\n      apiUsage: fdaAPIClient.getRateLimitInfo(),\n    }\n  } catch (error) {\n    return {\n      success: false,\n      error: error instanceof Error ? error.message : String(error),\n    }\n  }\n}\n\n// Drug Enforcement (Recalls) Handler\nexport type DrugEnforcementParams = {\n  recallingFirm?: string\n  classification?: \"Class I\" | \"Class II\" | \"Class III\"\n  status?: \"Ongoing\" | \"Completed\" | \"Terminated\" | \"Pending\"\n  state?: string\n  dateFrom?: string\n  dateTo?: string\n  limit?: number\n  skip?: number\n}\n\ntype FormattedDrugEnforcement = {\n  recallNumber: string | undefined\n  recallingFirm: string | undefined\n  classification: string | undefined\n  status: string | undefined\n  productDescription: string | undefined\n  reasonForRecall: string | undefined\n  recallInitiationDate: string | undefined\n  distributionPattern: string | undefined\n  city: string | undefined\n  state: string | undefined\n}\n\nfunction formatDrugEnforcement(recall: DrugEnforcement): FormattedDrugEnforcement {\n  return {\n    recallNumber: recall.recall_number,\n    recallingFirm: recall.recalling_firm,\n    classification: recall.classification,\n    status: recall.status,\n    productDescription: truncateText(recall.product_description),\n    reasonForRecall: truncateText(recall.reason_for_recall),\n    recallInitiationDate: recall.recall_initiation_date,\n    distributionPattern: truncateText(recall.distribution_pattern),\n    city: recall.city,\n    state: recall.state,\n  }\n}\n\nexport async function handleSearchDrugEnforcement(\n  params: DrugEnforcementParams,\n): Promise<FDAToolResponse<FormattedDrugEnforcement[]>> {\n  loggers.tools(\"searchDrugEnforcement\", params)\n\n  try {\n    const searchTerms: Array<{ field: string; value?: string }> = [\n      { field: \"recalling_firm\", value: params.recallingFirm },\n      { field: \"classification\", value: params.classification },\n      { field: \"status\", value: params.status },\n      { field: \"state\", value: params.state },\n    ]\n\n    const searchQuery = buildSearchQuery(searchTerms)\n    const dateQuery = buildDateQuery(\"recall_initiation_date\", params.dateFrom, params.dateTo)\n    const fullQuery = [searchQuery, dateQuery].filter(Boolean).join(\"+AND+\")\n\n    const searchParams: SearchParams = {\n      search: fullQuery || undefined,\n      limit: params.limit,\n      skip: params.skip,\n    }\n\n    const response = await fdaAPIClient.searchDrugEnforcement(searchParams)\n    const results = response.results ?? []\n\n    return {\n      success: true,\n      data: results.map(formatDrugEnforcement),\n      totalResults: response.meta?.results?.total,\n      displayedResults: results.length,\n      searchParams,\n      apiUsage: fdaAPIClient.getRateLimitInfo(),\n    }\n  } catch (error) {\n    return {\n      success: false,\n      error: error instanceof Error ? error.message : String(error),\n    }\n  }\n}\n\n// Drugs@FDA Handler\nexport type DrugsFDAParams = {\n  sponsorName?: string\n  applicationNumber?: string\n  brandName?: string\n  marketingStatus?: string\n  limit?: number\n  skip?: number\n}\n\ntype FormattedDrugsFDA = {\n  applicationNumber: string | undefined\n  sponsorName: string | undefined\n  products: Array<{\n    brandName: string | undefined\n    dosageForm: string | undefined\n    route: string | undefined\n    marketingStatus: string | undefined\n    activeIngredients: Array<{ name: string | undefined; strength: string | undefined }>\n  }>\n  latestSubmission:\n    | {\n        type: string | undefined\n        status: string | undefined\n        statusDate: string | undefined\n      }\n    | undefined\n}\n\nfunction formatDrugsFDA(drug: DrugsFDA): FormattedDrugsFDA {\n  const latestSubmission = drug.submissions?.[0]\n\n  return {\n    applicationNumber: drug.application_number,\n    sponsorName: drug.sponsor_name,\n    products:\n      drug.products?.slice(0, 3).map((p) => ({\n        brandName: p.brand_name,\n        dosageForm: p.dosage_form,\n        route: p.route,\n        marketingStatus: p.marketing_status,\n        activeIngredients:\n          p.active_ingredients?.slice(0, 3).map((ai) => ({\n            name: ai.name,\n            strength: ai.strength,\n          })) ?? [],\n      })) ?? [],\n    latestSubmission: latestSubmission\n      ? {\n          type: latestSubmission.submission_type,\n          status: latestSubmission.submission_status,\n          statusDate: latestSubmission.submission_status_date,\n        }\n      : undefined,\n  }\n}\n\nexport async function handleSearchDrugsFDA(params: DrugsFDAParams): Promise<FDAToolResponse<FormattedDrugsFDA[]>> {\n  loggers.tools(\"searchDrugsFDA\", params)\n\n  try {\n    const searchTerms: Array<{ field: string; value?: string }> = [\n      { field: \"sponsor_name\", value: params.sponsorName },\n      { field: \"application_number\", value: params.applicationNumber },\n      { field: \"products.brand_name\", value: params.brandName },\n      { field: \"products.marketing_status\", value: params.marketingStatus },\n    ]\n\n    const searchQuery = buildSearchQuery(searchTerms)\n\n    const searchParams: SearchParams = {\n      search: searchQuery || undefined,\n      limit: params.limit,\n      skip: params.skip,\n    }\n\n    const response = await fdaAPIClient.searchDrugsFDA(searchParams)\n    const results = response.results ?? []\n\n    return {\n      success: true,\n      data: results.map(formatDrugsFDA),\n      totalResults: response.meta?.results?.total,\n      displayedResults: results.length,\n      searchParams,\n      apiUsage: fdaAPIClient.getRateLimitInfo(),\n    }\n  } catch (error) {\n    return {\n      success: false,\n      error: error instanceof Error ? error.message : String(error),\n    }\n  }\n}\n\n// Drug Shortages Handler\nexport type DrugShortagesParams = {\n  genericName?: string\n  status?: \"Current\" | \"Resolved\"\n  limit?: number\n  skip?: number\n}\n\ntype FormattedDrugShortage = {\n  genericName: string | undefined\n  proprietaryName: string | undefined\n  status: string | undefined\n  description: string | undefined\n  initialPostingDate: string | undefined\n  resolvedShortageDate: string | undefined\n}\n\nfunction formatDrugShortage(shortage: DrugShortage): FormattedDrugShortage {\n  return {\n    genericName: shortage.generic_name,\n    proprietaryName: shortage.proprietary_name,\n    status: shortage.status,\n    description: truncateText(shortage.description),\n    initialPostingDate: shortage.initial_posting_date,\n    resolvedShortageDate: shortage.resolved_shortage_date,\n  }\n}\n\nexport async function handleSearchDrugShortages(\n  params: DrugShortagesParams,\n): Promise<FDAToolResponse<FormattedDrugShortage[]>> {\n  loggers.tools(\"searchDrugShortages\", params)\n\n  try {\n    const searchTerms: Array<{ field: string; value?: string }> = [\n      { field: \"generic_name\", value: params.genericName },\n      { field: \"status\", value: params.status },\n    ]\n\n    const searchQuery = buildSearchQuery(searchTerms)\n\n    const searchParams: SearchParams = {\n      search: searchQuery || undefined,\n      limit: params.limit,\n      skip: params.skip,\n    }\n\n    const response = await fdaAPIClient.searchDrugShortages(searchParams)\n    const results = response.results ?? []\n\n    return {\n      success: true,\n      data: results.map(formatDrugShortage),\n      totalResults: response.meta?.results?.total,\n      displayedResults: results.length,\n      searchParams,\n      apiUsage: fdaAPIClient.getRateLimitInfo(),\n    }\n  } catch (error) {\n    return {\n      success: false,\n      error: error instanceof Error ? error.message : String(error),\n    }\n  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package/dist/index.js

@@ -1,3 +1,3 @@
 #!/usr/bin/env node
-import{loggers as e}from"./utils/logger.js";import"./api-client-BGnUXMwX.js";import"./device-handlers-D01LfIJk.js";import"./drug-handlers-Fz_6NLl5.js";import"./tools-Bh3wjIRH.js";import{createOpenFDAServer as t}from"./server.js";import{Command as n}from"commander";const r=new n;r.name(`openfda-mcp-server`).description(`MCP server for querying U.S. FDA public datasets`).version(`0.1.0`).option(`-t, --transport <type>`,`Transport type (stdio or http)`,`stdio`).option(`-p, --port <number>`,`Port for HTTP transport`,`3000`).option(`--host <host>`,`Host for HTTP transport`,`localhost`).action(async n=>{let{transport:r,port:i,host:a}=n;e.main(`Starting OpenFDA MCP server with transport: ${r}`);let o=t({name:`openfda-mcp-server`,version:`0.1.0`});try{if(r===`http`){let t=parseInt(i,10);e.main(`Starting HTTP server on ${a}:${t}`),await o.start({transportType:`httpStream`,httpStream:{endpoint:`/mcp`,port:t}}),console.error(`OpenFDA MCP server running at http://${a}:${t}/mcp`)}else e.main(`Starting stdio server`),await o.start({transportType:`stdio`})}catch(e){console.error(`Failed to start server:`,e),process.exit(1)}}),r.parse();export{};
+import{loggers as e}from"./utils/logger.js";import{createOpenFDAServer as t}from"./server.js";import{Command as n}from"commander";const r=new n;r.name(`openfda-mcp-server`).description(`MCP server for querying U.S. FDA public datasets`).version(`0.1.0`).option(`-t, --transport <type>`,`Transport type (stdio or http)`,`stdio`).option(`-p, --port <number>`,`Port for HTTP transport`,`3000`).option(`--host <host>`,`Host for HTTP transport`,`localhost`).action(async n=>{let{transport:r,port:i,host:a}=n;e.main(`Starting OpenFDA MCP server with transport: ${r}`);let o=t({name:`openfda-mcp-server`,version:`0.1.0`});try{if(r===`http`){let t=parseInt(i,10);e.main(`Starting HTTP server on ${a}:${t}`),await o.start({transportType:`httpStream`,httpStream:{endpoint:`/mcp`,port:t}}),console.error(`OpenFDA MCP server running at http://${a}:${t}/mcp`)}else e.main(`Starting stdio server`),await o.start({transportType:`stdio`})}catch(e){console.error(`Failed to start server:`,e),process.exit(1)}}),r.parse();export{};
 //# sourceMappingURL=index.js.map

package/dist/index.js.map

@@ -1 +1 @@
-{"version":3,"file":"index.js","names":[],"sources":["../src/index.ts"],"sourcesContent":["#!/usr/bin/env node\n/**\n * OpenFDA MCP Server CLI\n * Command-line interface for starting the MCP server\n */\n\nimport { Command } from \"commander\"\n\nimport { createOpenFDAServer } from \"./server.js\"\nimport { loggers } from \"./utils/logger.js\"\n\nconst program = new Command()\n\nprogram\n  .name(\"openfda-mcp-server\")\n  .description(\"MCP server for querying U.S. FDA public datasets\")\n  .version(\"0.1.0\")\n  .option(\"-t, --transport <type>\", \"Transport type (stdio or http)\", \"stdio\")\n  .option(\"-p, --port <number>\", \"Port for HTTP transport\", \"3000\")\n  .option(\"--host <host>\", \"Host for HTTP transport\", \"localhost\")\n  .action(async (options) => {\n    const { transport, port, host } = options\n\n    loggers.main(`Starting OpenFDA MCP server with transport: ${transport}`)\n\n    const server = createOpenFDAServer({\n      name: \"openfda-mcp-server\",\n      version: \"0.1.0\" as `${number}.${number}.${number}`,\n    })\n\n    try {\n      if (transport === \"http\") {\n        const portNum = parseInt(port, 10)\n        loggers.main(`Starting HTTP server on ${host}:${portNum}`)\n\n        await server.start({\n          transportType: \"httpStream\",\n          httpStream: {\n            endpoint: \"/mcp\" as `/${string}`,\n            port: portNum,\n          },\n        })\n\n        console.error(`OpenFDA MCP server running at http://${host}:${portNum}/mcp`)\n      } else {\n        loggers.main(\"Starting stdio server\")\n\n        await server.start({\n          transportType: \"stdio\",\n        })\n      }\n    } catch (error) {\n      console.error(\"Failed to start server:\", error)\n      process.exit(1)\n    }\n  })\n\nprogram.parse()\n"],"mappings":";yQAWA,MAAM,EAAU,IAAI,EAEpB,EACG,KAAK,qBAAqB,CAC1B,YAAY,mDAAmD,CAC/D,QAAQ,QAAQ,CAChB,OAAO,yBAA0B,iCAAkC,QAAQ,CAC3E,OAAO,sBAAuB,0BAA2B,OAAO,CAChE,OAAO,gBAAiB,0BAA2B,YAAY,CAC/D,OAAO,KAAO,IAAY,CACzB,GAAM,CAAE,YAAW,OAAM,QAAS,EAElC,EAAQ,KAAK,+CAA+C,IAAY,CAExE,IAAM,EAAS,EAAoB,CACjC,KAAM,qBACN,QAAS,QACV,CAAC,CAEF,GAAI,CACF,GAAI,IAAc,OAAQ,CACxB,IAAM,EAAU,SAAS,EAAM,GAAG,CAClC,EAAQ,KAAK,2BAA2B,EAAK,GAAG,IAAU,CAE1D,MAAM,EAAO,MAAM,CACjB,cAAe,aACf,WAAY,CACV,SAAU,OACV,KAAM,EACP,CACF,CAAC,CAEF,QAAQ,MAAM,wCAAwC,EAAK,GAAG,EAAQ,MAAM,MAE5E,EAAQ,KAAK,wBAAwB,CAErC,MAAM,EAAO,MAAM,CACjB,cAAe,QAChB,CAAC,OAEG,EAAO,CACd,QAAQ,MAAM,0BAA2B,EAAM,CAC/C,QAAQ,KAAK,EAAE,GAEjB,CAEJ,EAAQ,OAAO"}
+{"version":3,"file":"index.js","names":[],"sources":["../src/index.ts"],"sourcesContent":["#!/usr/bin/env node\n/**\n * OpenFDA MCP Server CLI\n * Command-line interface for starting the MCP server\n */\n\nimport { Command } from \"commander\"\n\nimport { createOpenFDAServer } from \"./server.js\"\nimport { loggers } from \"./utils/logger.js\"\n\nconst program = new Command()\n\nprogram\n  .name(\"openfda-mcp-server\")\n  .description(\"MCP server for querying U.S. FDA public datasets\")\n  .version(\"0.1.0\")\n  .option(\"-t, --transport <type>\", \"Transport type (stdio or http)\", \"stdio\")\n  .option(\"-p, --port <number>\", \"Port for HTTP transport\", \"3000\")\n  .option(\"--host <host>\", \"Host for HTTP transport\", \"localhost\")\n  .action(async (options) => {\n    const { transport, port, host } = options\n\n    loggers.main(`Starting OpenFDA MCP server with transport: ${transport}`)\n\n    const server = createOpenFDAServer({\n      name: \"openfda-mcp-server\",\n      version: \"0.1.0\" as `${number}.${number}.${number}`,\n    })\n\n    try {\n      if (transport === \"http\") {\n        const portNum = parseInt(port, 10)\n        loggers.main(`Starting HTTP server on ${host}:${portNum}`)\n\n        await server.start({\n          transportType: \"httpStream\",\n          httpStream: {\n            endpoint: \"/mcp\" as `/${string}`,\n            port: portNum,\n          },\n        })\n\n        console.error(`OpenFDA MCP server running at http://${host}:${portNum}/mcp`)\n      } else {\n        loggers.main(\"Starting stdio server\")\n\n        await server.start({\n          transportType: \"stdio\",\n        })\n      }\n    } catch (error) {\n      console.error(\"Failed to start server:\", error)\n      process.exit(1)\n    }\n  })\n\nprogram.parse()\n"],"mappings":";kIAWA,MAAM,EAAU,IAAI,EAEpB,EACG,KAAK,qBAAqB,CAC1B,YAAY,mDAAmD,CAC/D,QAAQ,QAAQ,CAChB,OAAO,yBAA0B,iCAAkC,QAAQ,CAC3E,OAAO,sBAAuB,0BAA2B,OAAO,CAChE,OAAO,gBAAiB,0BAA2B,YAAY,CAC/D,OAAO,KAAO,IAAY,CACzB,GAAM,CAAE,YAAW,OAAM,QAAS,EAElC,EAAQ,KAAK,+CAA+C,IAAY,CAExE,IAAM,EAAS,EAAoB,CACjC,KAAM,qBACN,QAAS,QACV,CAAC,CAEF,GAAI,CACF,GAAI,IAAc,OAAQ,CACxB,IAAM,EAAU,SAAS,EAAM,GAAG,CAClC,EAAQ,KAAK,2BAA2B,EAAK,GAAG,IAAU,CAE1D,MAAM,EAAO,MAAM,CACjB,cAAe,aACf,WAAY,CACV,SAAU,OACV,KAAM,EACP,CACF,CAAC,CAEF,QAAQ,MAAM,wCAAwC,EAAK,GAAG,EAAQ,MAAM,MAE5E,EAAQ,KAAK,wBAAwB,CAErC,MAAM,EAAO,MAAM,CACjB,cAAe,QAChB,CAAC,OAEG,EAAO,CACd,QAAQ,MAAM,0BAA2B,EAAM,CAC/C,QAAQ,KAAK,EAAE,GAEjB,CAEJ,EAAQ,OAAO"}