oncoprintjs 5.0.4 → 6.0.0

package/dist/oncoprint.bundle.js

@@ -1,33 +0,0 @@
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t[0]=1,t[1]=0,t[2]=0,t[3]=0,t[4]=0,t[5]=1,t[6]=0,t[7]=0,t[8]=0,t[9]=0,t[10]=1,t[11]=0,t[12]=0,t[13]=0,t[14]=0,t[15]=1,t},clone:function(t){var e=new r.ARRAY_TYPE(16);return e[0]=t[0],e[1]=t[1],e[2]=t[2],e[3]=t[3],e[4]=t[4],e[5]=t[5],e[6]=t[6],e[7]=t[7],e[8]=t[8],e[9]=t[9],e[10]=t[10],e[11]=t[11],e[12]=t[12],e[13]=t[13],e[14]=t[14],e[15]=t[15],e},copy:function(t,e){return t[0]=e[0],t[1]=e[1],t[2]=e[2],t[3]=e[3],t[4]=e[4],t[5]=e[5],t[6]=e[6],t[7]=e[7],t[8]=e[8],t[9]=e[9],t[10]=e[10],t[11]=e[11],t[12]=e[12],t[13]=e[13],t[14]=e[14],t[15]=e[15],t},fromValues:function(t,e,n,i,o,s,a,l,u,c,h,f,d,p,g,m){var _=new r.ARRAY_TYPE(16);return _[0]=t,_[1]=e,_[2]=n,_[3]=i,_[4]=o,_[5]=s,_[6]=a,_[7]=l,_[8]=u,_[9]=c,_[10]=h,_[11]=f,_[12]=d,_[13]=p,_[14]=g,_[15]=m,_},set:function(t,e,n,r,i,o,s,a,l,u,c,h,f,d,p,g,m){return t[0]=e,t[1]=n,t[2]=r,t[3]=i,t[4]=o,t[5]=s,t[6]=a,t[7]=l,t[8]=u,t[9]=c,t[10]=h,t[11]=f,t[12]=d,t[13]=p,t[14]=g,t[15]=m,t},identity:function(t){return t[0]=1,t[1]=0,t[2]=0,t[3]=0,t[4]=0,t[5]=1,t[6]=0,t[7]=0,t[8]=0,t[9]=0,t[10]=1,t[11]=0,t[12]=0,t[13]=0,t[14]=0,t[15]=1,t}};i.scalar.transpose=function(t,e){if(t===e){var n=e[1],r=e[2],i=e[3],o=e[6],s=e[7],a=e[11];t[1]=e[4],t[2]=e[8],t[3]=e[12],t[4]=n,t[6]=e[9],t[7]=e[13],t[8]=r,t[9]=o,t[11]=e[14],t[12]=i,t[13]=s,t[14]=a}else t[0]=e[0],t[1]=e[4],t[2]=e[8],t[3]=e[12],t[4]=e[1],t[5]=e[5],t[6]=e[9],t[7]=e[13],t[8]=e[2],t[9]=e[6],t[10]=e[10],t[11]=e[14],t[12]=e[3],t[13]=e[7],t[14]=e[11],t[15]=e[15];return t},i.SIMD.transpose=function(t,e){var n,r,i,o,s,a,l,u,c,h;return n=SIMD.Float32x4.load(e,0),r=SIMD.Float32x4.load(e,4),i=SIMD.Float32x4.load(e,8),o=SIMD.Float32x4.load(e,12),s=SIMD.Float32x4.shuffle(n,r,0,1,4,5),a=SIMD.Float32x4.shuffle(i,o,0,1,4,5),l=SIMD.Float32x4.shuffle(s,a,0,2,4,6),u=SIMD.Float32x4.shuffle(s,a,1,3,5,7),SIMD.Float32x4.store(t,0,l),SIMD.Float32x4.store(t,4,u),s=SIMD.Float32x4.shuffle(n,r,2,3,6,7),a=SIMD.Float32x4.shuffle(i,o,2,3,6,7),c=SIMD.Float32x4.shuffle(s,a,0,2,4,6),h=SIMD.Float32x4.shuffle(s,a,1,3,5,7),SIMD.Float32x4.store(t,8,c),SIMD.Float32x4.store(t,12,h),t},i.transpose=r.USE_SIMD?i.SIMD.transpose:i.scalar.transpose,i.scalar.invert=function(t,e){var n=e[0],r=e[1],i=e[2],o=e[3],s=e[4],a=e[5],l=e[6],u=e[7],c=e[8],h=e[9],f=e[10],d=e[11],p=e[12],g=e[13],m=e[14],_=e[15],v=n*a-r*s,b=n*l-i*s,x=n*u-o*s,y=r*l-i*a,w=r*u-o*a,k=i*u-o*l,S=c*g-h*p,M=c*m-f*p,T=c*_-d*p,I=h*m-f*g,A=h*_-d*g,C=f*_-d*m,D=v*C-b*A+x*I+y*T-w*M+k*S;return D?(D=1/D,t[0]=(a*C-l*A+u*I)*D,t[1]=(i*A-r*C-o*I)*D,t[2]=(g*k-m*w+_*y)*D,t[3]=(f*w-h*k-d*y)*D,t[4]=(l*T-s*C-u*M)*D,t[5]=(n*C-i*T+o*M)*D,t[6]=(m*x-p*k-_*b)*D,t[7]=(c*k-f*x+d*b)*D,t[8]=(s*A-a*T+u*S)*D,t[9]=(r*T-n*A-o*S)*D,t[10]=(p*w-g*x+_*v)*D,t[11]=(h*x-c*w-d*v)*D,t[12]=(a*M-s*I-l*S)*D,t[13]=(n*I-r*M+i*S)*D,t[14]=(g*b-p*y-m*v)*D,t[15]=(c*y-h*b+f*v)*D,t):null},i.SIMD.invert=function(t,e){var n,r,i,o,s,a,l,u,c,h,f=SIMD.Float32x4.load(e,0),d=SIMD.Float32x4.load(e,4),p=SIMD.Float32x4.load(e,8),g=SIMD.Float32x4.load(e,12);return s=SIMD.Float32x4.shuffle(f,d,0,1,4,5),r=SIMD.Float32x4.shuffle(p,g,0,1,4,5),n=SIMD.Float32x4.shuffle(s,r,0,2,4,6),r=SIMD.Float32x4.shuffle(r,s,1,3,5,7),s=SIMD.Float32x4.shuffle(f,d,2,3,6,7),o=SIMD.Float32x4.shuffle(p,g,2,3,6,7),i=SIMD.Float32x4.shuffle(s,o,0,2,4,6),o=SIMD.Float32x4.shuffle(o,s,1,3,5,7),s=SIMD.Float32x4.mul(i,o),s=SIMD.Float32x4.swizzle(s,1,0,3,2),a=SIMD.Float32x4.mul(r,s),l=SIMD.Float32x4.mul(n,s),s=SIMD.Float32x4.swizzle(s,2,3,0,1),a=SIMD.Float32x4.sub(SIMD.Float32x4.mul(r,s),a),l=SIMD.Float32x4.sub(SIMD.Float32x4.mul(n,s),l),l=SIMD.Float32x4.swizzle(l,2,3,0,1),s=SIMD.Float32x4.mul(r,i),s=SIMD.Float32x4.swizzle(s,1,0,3,2),a=SIMD.Float32x4.add(SIMD.Float32x4.mul(o,s),a),c=SIMD.Float32x4.mul(n,s),s=SIMD.Float32x4.swizzle(s,2,3,0,1),a=SIMD.Float32x4.sub(a,SIMD.Float32x4.mul(o,s)),c=SIMD.Float32x4.sub(SIMD.Float32x4.mul(n,s),c),c=SIMD.Float32x4.swizzle(c,2,3,0,1),s=SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(r,2,3,0,1),o),s=SIMD.Float32x4.swizzle(s,1,0,3,2),i=SIMD.Float32x4.swizzle(i,2,3,0,1),a=SIMD.Float32x4.add(SIMD.Float32x4.mul(i,s),a),u=SIMD.Float32x4.mul(n,s),s=SIMD.Float32x4.swizzle(s,2,3,0,1),a=SIMD.Float32x4.sub(a,SIMD.Float32x4.mul(i,s)),u=SIMD.Float32x4.sub(SIMD.Float32x4.mul(n,s),u),u=SIMD.Float32x4.swizzle(u,2,3,0,1),s=SIMD.Float32x4.mul(n,r),s=SIMD.Float32x4.swizzle(s,1,0,3,2),u=SIMD.Float32x4.add(SIMD.Float32x4.mul(o,s),u),c=SIMD.Float32x4.sub(SIMD.Float32x4.mul(i,s),c),s=SIMD.Float32x4.swizzle(s,2,3,0,1),u=SIMD.Float32x4.sub(SIMD.Float32x4.mul(o,s),u),c=SIMD.Float32x4.sub(c,SIMD.Float32x4.mul(i,s)),s=SIMD.Float32x4.mul(n,o),s=SIMD.Float32x4.swizzle(s,1,0,3,2),l=SIMD.Float32x4.sub(l,SIMD.Float32x4.mul(i,s)),u=SIMD.Float32x4.add(SIMD.Float32x4.mul(r,s),u),s=SIMD.Float32x4.swizzle(s,2,3,0,1),l=SIMD.Float32x4.add(SIMD.Float32x4.mul(i,s),l),u=SIMD.Float32x4.sub(u,SIMD.Float32x4.mul(r,s)),s=SIMD.Float32x4.mul(n,i),s=SIMD.Float32x4.swizzle(s,1,0,3,2),l=SIMD.Float32x4.add(SIMD.Float32x4.mul(o,s),l),c=SIMD.Float32x4.sub(c,SIMD.Float32x4.mul(r,s)),s=SIMD.Float32x4.swizzle(s,2,3,0,1),l=SIMD.Float32x4.sub(l,SIMD.Float32x4.mul(o,s)),c=SIMD.Float32x4.add(SIMD.Float32x4.mul(r,s),c),h=SIMD.Float32x4.mul(n,a),h=SIMD.Float32x4.add(SIMD.Float32x4.swizzle(h,2,3,0,1),h),h=SIMD.Float32x4.add(SIMD.Float32x4.swizzle(h,1,0,3,2),h),s=SIMD.Float32x4.reciprocalApproximation(h),h=SIMD.Float32x4.sub(SIMD.Float32x4.add(s,s),SIMD.Float32x4.mul(h,SIMD.Float32x4.mul(s,s))),(h=SIMD.Float32x4.swizzle(h,0,0,0,0))?(SIMD.Float32x4.store(t,0,SIMD.Float32x4.mul(h,a)),SIMD.Float32x4.store(t,4,SIMD.Float32x4.mul(h,l)),SIMD.Float32x4.store(t,8,SIMD.Float32x4.mul(h,u)),SIMD.Float32x4.store(t,12,SIMD.Float32x4.mul(h,c)),t):null},i.invert=r.USE_SIMD?i.SIMD.invert:i.scalar.invert,i.scalar.adjoint=function(t,e){var n=e[0],r=e[1],i=e[2],o=e[3],s=e[4],a=e[5],l=e[6],u=e[7],c=e[8],h=e[9],f=e[10],d=e[11],p=e[12],g=e[13],m=e[14],_=e[15];return t[0]=a*(f*_-d*m)-h*(l*_-u*m)+g*(l*d-u*f),t[1]=-(r*(f*_-d*m)-h*(i*_-o*m)+g*(i*d-o*f)),t[2]=r*(l*_-u*m)-a*(i*_-o*m)+g*(i*u-o*l),t[3]=-(r*(l*d-u*f)-a*(i*d-o*f)+h*(i*u-o*l)),t[4]=-(s*(f*_-d*m)-c*(l*_-u*m)+p*(l*d-u*f)),t[5]=n*(f*_-d*m)-c*(i*_-o*m)+p*(i*d-o*f),t[6]=-(n*(l*_-u*m)-s*(i*_-o*m)+p*(i*u-o*l)),t[7]=n*(l*d-u*f)-s*(i*d-o*f)+c*(i*u-o*l),t[8]=s*(h*_-d*g)-c*(a*_-u*g)+p*(a*d-u*h),t[9]=-(n*(h*_-d*g)-c*(r*_-o*g)+p*(r*d-o*h)),t[10]=n*(a*_-u*g)-s*(r*_-o*g)+p*(r*u-o*a),t[11]=-(n*(a*d-u*h)-s*(r*d-o*h)+c*(r*u-o*a)),t[12]=-(s*(h*m-f*g)-c*(a*m-l*g)+p*(a*f-l*h)),t[13]=n*(h*m-f*g)-c*(r*m-i*g)+p*(r*f-i*h),t[14]=-(n*(a*m-l*g)-s*(r*m-i*g)+p*(r*l-i*a)),t[15]=n*(a*f-l*h)-s*(r*f-i*h)+c*(r*l-i*a),t},i.SIMD.adjoint=function(t,e){var n,r,i,o,s,a,l,u,c,h=SIMD.Float32x4.load(e,0),f=SIMD.Float32x4.load(e,4),d=SIMD.Float32x4.load(e,8),p=SIMD.Float32x4.load(e,12);return s=SIMD.Float32x4.shuffle(h,f,0,1,4,5),r=SIMD.Float32x4.shuffle(d,p,0,1,4,5),n=SIMD.Float32x4.shuffle(s,r,0,2,4,6),r=SIMD.Float32x4.shuffle(r,s,1,3,5,7),s=SIMD.Float32x4.shuffle(h,f,2,3,6,7),o=SIMD.Float32x4.shuffle(d,p,2,3,6,7),i=SIMD.Float32x4.shuffle(s,o,0,2,4,6),o=SIMD.Float32x4.shuffle(o,s,1,3,5,7),s=SIMD.Float32x4.mul(i,o),s=SIMD.Float32x4.swizzle(s,1,0,3,2),a=SIMD.Float32x4.mul(r,s),l=SIMD.Float32x4.mul(n,s),s=SIMD.Float32x4.swizzle(s,2,3,0,1),a=SIMD.Float32x4.sub(SIMD.Float32x4.mul(r,s),a),l=SIMD.Float32x4.sub(SIMD.Float32x4.mul(n,s),l),l=SIMD.Float32x4.swizzle(l,2,3,0,1),s=SIMD.Float32x4.mul(r,i),s=SIMD.Float32x4.swizzle(s,1,0,3,2),a=SIMD.Float32x4.add(SIMD.Float32x4.mul(o,s),a),c=SIMD.Float32x4.mul(n,s),s=SIMD.Float32x4.swizzle(s,2,3,0,1),a=SIMD.Float32x4.sub(a,SIMD.Float32x4.mul(o,s)),c=SIMD.Float32x4.sub(SIMD.Float32x4.mul(n,s),c),c=SIMD.Float32x4.swizzle(c,2,3,0,1),s=SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(r,2,3,0,1),o),s=SIMD.Float32x4.swizzle(s,1,0,3,2),i=SIMD.Float32x4.swizzle(i,2,3,0,1),a=SIMD.Float32x4.add(SIMD.Float32x4.mul(i,s),a),u=SIMD.Float32x4.mul(n,s),s=SIMD.Float32x4.swizzle(s,2,3,0,1),a=SIMD.Float32x4.sub(a,SIMD.Float32x4.mul(i,s)),u=SIMD.Float32x4.sub(SIMD.Float32x4.mul(n,s),u),u=SIMD.Float32x4.swizzle(u,2,3,0,1),s=SIMD.Float32x4.mul(n,r),s=SIMD.Float32x4.swizzle(s,1,0,3,2),u=SIMD.Float32x4.add(SIMD.Float32x4.mul(o,s),u),c=SIMD.Float32x4.sub(SIMD.Float32x4.mul(i,s),c),s=SIMD.Float32x4.swizzle(s,2,3,0,1),u=SIMD.Float32x4.sub(SIMD.Float32x4.mul(o,s),u),c=SIMD.Float32x4.sub(c,SIMD.Float32x4.mul(i,s)),s=SIMD.Float32x4.mul(n,o),s=SIMD.Float32x4.swizzle(s,1,0,3,2),l=SIMD.Float32x4.sub(l,SIMD.Float32x4.mul(i,s)),u=SIMD.Float32x4.add(SIMD.Float32x4.mul(r,s),u),s=SIMD.Float32x4.swizzle(s,2,3,0,1),l=SIMD.Float32x4.add(SIMD.Float32x4.mul(i,s),l),u=SIMD.Float32x4.sub(u,SIMD.Float32x4.mul(r,s)),s=SIMD.Float32x4.mul(n,i),s=SIMD.Float32x4.swizzle(s,1,0,3,2),l=SIMD.Float32x4.add(SIMD.Float32x4.mul(o,s),l),c=SIMD.Float32x4.sub(c,SIMD.Float32x4.mul(r,s)),s=SIMD.Float32x4.swizzle(s,2,3,0,1),l=SIMD.Float32x4.sub(l,SIMD.Float32x4.mul(o,s)),c=SIMD.Float32x4.add(SIMD.Float32x4.mul(r,s),c),SIMD.Float32x4.store(t,0,a),SIMD.Float32x4.store(t,4,l),SIMD.Float32x4.store(t,8,u),SIMD.Float32x4.store(t,12,c),t},i.adjoint=r.USE_SIMD?i.SIMD.adjoint:i.scalar.adjoint,i.determinant=function(t){var e=t[0],n=t[1],r=t[2],i=t[3],o=t[4],s=t[5],a=t[6],l=t[7],u=t[8],c=t[9],h=t[10],f=t[11],d=t[12],p=t[13],g=t[14],m=t[15];return(e*s-n*o)*(h*m-f*g)-(e*a-r*o)*(c*m-f*p)+(e*l-i*o)*(c*g-h*p)+(n*a-r*s)*(u*m-f*d)-(n*l-i*s)*(u*g-h*d)+(r*l-i*a)*(u*p-c*d)},i.SIMD.multiply=function(t,e,n){var r=SIMD.Float32x4.load(e,0),i=SIMD.Float32x4.load(e,4),o=SIMD.Float32x4.load(e,8),s=SIMD.Float32x4.load(e,12),a=SIMD.Float32x4.load(n,0),l=SIMD.Float32x4.add(SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(a,0,0,0,0),r),SIMD.Float32x4.add(SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(a,1,1,1,1),i),SIMD.Float32x4.add(SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(a,2,2,2,2),o),SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(a,3,3,3,3),s))));SIMD.Float32x4.store(t,0,l);var u=SIMD.Float32x4.load(n,4),c=SIMD.Float32x4.add(SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(u,0,0,0,0),r),SIMD.Float32x4.add(SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(u,1,1,1,1),i),SIMD.Float32x4.add(SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(u,2,2,2,2),o),SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(u,3,3,3,3),s))));SIMD.Float32x4.store(t,4,c);var h=SIMD.Float32x4.load(n,8),f=SIMD.Float32x4.add(SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(h,0,0,0,0),r),SIMD.Float32x4.add(SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(h,1,1,1,1),i),SIMD.Float32x4.add(SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(h,2,2,2,2),o),SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(h,3,3,3,3),s))));SIMD.Float32x4.store(t,8,f);var d=SIMD.Float32x4.load(n,12),p=SIMD.Float32x4.add(SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(d,0,0,0,0),r),SIMD.Float32x4.add(SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(d,1,1,1,1),i),SIMD.Float32x4.add(SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(d,2,2,2,2),o),SIMD.Float32x4.mul(SIMD.Float32x4.swizzle(d,3,3,3,3),s))));return SIMD.Float32x4.store(t,12,p),t},i.scalar.multiply=function(t,e,n){var r=e[0],i=e[1],o=e[2],s=e[3],a=e[4],l=e[5],u=e[6],c=e[7],h=e[8],f=e[9],d=e[10],p=e[11],g=e[12],m=e[13],_=e[14],v=e[15],b=n[0],x=n[1],y=n[2],w=n[3];return t[0]=b*r+x*a+y*h+w*g,t[1]=b*i+x*l+y*f+w*m,t[2]=b*o+x*u+y*d+w*_,t[3]=b*s+x*c+y*p+w*v,b=n[4],x=n[5],y=n[6],w=n[7],t[4]=b*r+x*a+y*h+w*g,t[5]=b*i+x*l+y*f+w*m,t[6]=b*o+x*u+y*d+w*_,t[7]=b*s+x*c+y*p+w*v,b=n[8],x=n[9],y=n[10],w=n[11],t[8]=b*r+x*a+y*h+w*g,t[9]=b*i+x*l+y*f+w*m,t[10]=b*o+x*u+y*d+w*_,t[11]=b*s+x*c+y*p+w*v,b=n[12],x=n[13],y=n[14],w=n[15],t[12]=b*r+x*a+y*h+w*g,t[13]=b*i+x*l+y*f+w*m,t[14]=b*o+x*u+y*d+w*_,t[15]=b*s+x*c+y*p+w*v,t},i.multiply=r.USE_SIMD?i.SIMD.multiply:i.scalar.multiply,i.mul=i.multiply,i.scalar.translate=function(t,e,n){var r,i,o,s,a,l,u,c,h,f,d,p,g=n[0],m=n[1],_=n[2];return e===t?(t[12]=e[0]*g+e[4]*m+e[8]*_+e[12],t[13]=e[1]*g+e[5]*m+e[9]*_+e[13],t[14]=e[2]*g+e[6]*m+e[10]*_+e[14],t[15]=e[3]*g+e[7]*m+e[11]*_+e[15]):(r=e[0],i=e[1],o=e[2],s=e[3],a=e[4],l=e[5],u=e[6],c=e[7],h=e[8],f=e[9],d=e[10],p=e[11],t[0]=r,t[1]=i,t[2]=o,t[3]=s,t[4]=a,t[5]=l,t[6]=u,t[7]=c,t[8]=h,t[9]=f,t[10]=d,t[11]=p,t[12]=r*g+a*m+h*_+e[12],t[13]=i*g+l*m+f*_+e[13],t[14]=o*g+u*m+d*_+e[14],t[15]=s*g+c*m+p*_+e[15]),t},i.SIMD.translate=function(t,e,n){var r=SIMD.Float32x4.load(e,0),i=SIMD.Float32x4.load(e,4),o=SIMD.Float32x4.load(e,8),s=SIMD.Float32x4.load(e,12),a=SIMD.Float32x4(n[0],n[1],n[2],0);e!==t&&(t[0]=e[0],t[1]=e[1],t[2]=e[2],t[3]=e[3],t[4]=e[4],t[5]=e[5],t[6]=e[6],t[7]=e[7],t[8]=e[8],t[9]=e[9],t[10]=e[10],t[11]=e[11]),r=SIMD.Float32x4.mul(r,SIMD.Float32x4.swizzle(a,0,0,0,0)),i=SIMD.Float32x4.mul(i,SIMD.Float32x4.swizzle(a,1,1,1,1)),o=SIMD.Float32x4.mul(o,SIMD.Float32x4.swizzle(a,2,2,2,2));var l=SIMD.Float32x4.add(r,SIMD.Float32x4.add(i,SIMD.Float32x4.add(o,s)));return SIMD.Float32x4.store(t,12,l),t},i.translate=r.USE_SIMD?i.SIMD.translate:i.scalar.translate,i.scalar.scale=function(t,e,n){var r=n[0],i=n[1],o=n[2];return t[0]=e[0]*r,t[1]=e[1]*r,t[2]=e[2]*r,t[3]=e[3]*r,t[4]=e[4]*i,t[5]=e[5]*i,t[6]=e[6]*i,t[7]=e[7]*i,t[8]=e[8]*o,t[9]=e[9]*o,t[10]=e[10]*o,t[11]=e[11]*o,t[12]=e[12],t[13]=e[13],t[14]=e[14],t[15]=e[15],t},i.SIMD.scale=function(t,e,n){var r,i,o,s=SIMD.Float32x4(n[0],n[1],n[2],0);return r=SIMD.Float32x4.load(e,0),SIMD.Float32x4.store(t,0,SIMD.Float32x4.mul(r,SIMD.Float32x4.swizzle(s,0,0,0,0))),i=SIMD.Float32x4.load(e,4),SIMD.Float32x4.store(t,4,SIMD.Float32x4.mul(i,SIMD.Float32x4.swizzle(s,1,1,1,1))),o=SIMD.Float32x4.load(e,8),SIMD.Float32x4.store(t,8,SIMD.Float32x4.mul(o,SIMD.Float32x4.swizzle(s,2,2,2,2))),t[12]=e[12],t[13]=e[13],t[14]=e[14],t[15]=e[15],t},i.scale=r.USE_SIMD?i.SIMD.scale:i.scalar.scale,i.rotate=function(t,e,n,i){var o,s,a,l,u,c,h,f,d,p,g,m,_,v,b,x,y,w,k,S,M,T,I,A,C=i[0],D=i[1],z=i[2],R=Math.sqrt(C*C+D*D+z*z);return Math.abs(R)<r.EPSILON?null:(C*=R=1/R,D*=R,z*=R,o=Math.sin(n),a=1-(s=Math.cos(n)),l=e[0],u=e[1],c=e[2],h=e[3],f=e[4],d=e[5],p=e[6],g=e[7],m=e[8],_=e[9],v=e[10],b=e[11],x=C*C*a+s,y=D*C*a+z*o,w=z*C*a-D*o,k=C*D*a-z*o,S=D*D*a+s,M=z*D*a+C*o,T=C*z*a+D*o,I=D*z*a-C*o,A=z*z*a+s,t[0]=l*x+f*y+m*w,t[1]=u*x+d*y+_*w,t[2]=c*x+p*y+v*w,t[3]=h*x+g*y+b*w,t[4]=l*k+f*S+m*M,t[5]=u*k+d*S+_*M,t[6]=c*k+p*S+v*M,t[7]=h*k+g*S+b*M,t[8]=l*T+f*I+m*A,t[9]=u*T+d*I+_*A,t[10]=c*T+p*I+v*A,t[11]=h*T+g*I+b*A,e!==t&&(t[12]=e[12],t[13]=e[13],t[14]=e[14],t[15]=e[15]),t)},i.scalar.rotateX=function(t,e,n){var r=Math.sin(n),i=Math.cos(n),o=e[4],s=e[5],a=e[6],l=e[7],u=e[8],c=e[9],h=e[10],f=e[11];return e!==t&&(t[0]=e[0],t[1]=e[1],t[2]=e[2],t[3]=e[3],t[12]=e[12],t[13]=e[13],t[14]=e[14],t[15]=e[15]),t[4]=o*i+u*r,t[5]=s*i+c*r,t[6]=a*i+h*r,t[7]=l*i+f*r,t[8]=u*i-o*r,t[9]=c*i-s*r,t[10]=h*i-a*r,t[11]=f*i-l*r,t},i.SIMD.rotateX=function(t,e,n){var r=SIMD.Float32x4.splat(Math.sin(n)),i=SIMD.Float32x4.splat(Math.cos(n));e!==t&&(t[0]=e[0],t[1]=e[1],t[2]=e[2],t[3]=e[3],t[12]=e[12],t[13]=e[13],t[14]=e[14],t[15]=e[15]);var o=SIMD.Float32x4.load(e,4),s=SIMD.Float32x4.load(e,8);return SIMD.Float32x4.store(t,4,SIMD.Float32x4.add(SIMD.Float32x4.mul(o,i),SIMD.Float32x4.mul(s,r))),SIMD.Float32x4.store(t,8,SIMD.Float32x4.sub(SIMD.Float32x4.mul(s,i),SIMD.Float32x4.mul(o,r))),t},i.rotateX=r.USE_SIMD?i.SIMD.rotateX:i.scalar.rotateX,i.scalar.rotateY=function(t,e,n){var r=Math.sin(n),i=Math.cos(n),o=e[0],s=e[1],a=e[2],l=e[3],u=e[8],c=e[9],h=e[10],f=e[11];return e!==t&&(t[4]=e[4],t[5]=e[5],t[6]=e[6],t[7]=e[7],t[12]=e[12],t[13]=e[13],t[14]=e[14],t[15]=e[15]),t[0]=o*i-u*r,t[1]=s*i-c*r,t[2]=a*i-h*r,t[3]=l*i-f*r,t[8]=o*r+u*i,t[9]=s*r+c*i,t[10]=a*r+h*i,t[11]=l*r+f*i,t},i.SIMD.rotateY=function(t,e,n){var r=SIMD.Float32x4.splat(Math.sin(n)),i=SIMD.Float32x4.splat(Math.cos(n));e!==t&&(t[4]=e[4],t[5]=e[5],t[6]=e[6],t[7]=e[7],t[12]=e[12],t[13]=e[13],t[14]=e[14],t[15]=e[15]);var o=SIMD.Float32x4.load(e,0),s=SIMD.Float32x4.load(e,8);return SIMD.Float32x4.store(t,0,SIMD.Float32x4.sub(SIMD.Float32x4.mul(o,i),SIMD.Float32x4.mul(s,r))),SIMD.Float32x4.store(t,8,SIMD.Float32x4.add(SIMD.Float32x4.mul(o,r),SIMD.Float32x4.mul(s,i))),t},i.rotateY=r.USE_SIMD?i.SIMD.rotateY:i.scalar.rotateY,i.scalar.rotateZ=function(t,e,n){var r=Math.sin(n),i=Math.cos(n),o=e[0],s=e[1],a=e[2],l=e[3],u=e[4],c=e[5],h=e[6],f=e[7];return e!==t&&(t[8]=e[8],t[9]=e[9],t[10]=e[10],t[11]=e[11],t[12]=e[12],t[13]=e[13],t[14]=e[14],t[15]=e[15]),t[0]=o*i+u*r,t[1]=s*i+c*r,t[2]=a*i+h*r,t[3]=l*i+f*r,t[4]=u*i-o*r,t[5]=c*i-s*r,t[6]=h*i-a*r,t[7]=f*i-l*r,t},i.SIMD.rotateZ=function(t,e,n){var r=SIMD.Float32x4.splat(Math.sin(n)),i=SIMD.Float32x4.splat(Math.cos(n));e!==t&&(t[8]=e[8],t[9]=e[9],t[10]=e[10],t[11]=e[11],t[12]=e[12],t[13]=e[13],t[14]=e[14],t[15]=e[15]);var o=SIMD.Float32x4.load(e,0),s=SIMD.Float32x4.load(e,4);return SIMD.Float32x4.store(t,0,SIMD.Float32x4.add(SIMD.Float32x4.mul(o,i),SIMD.Float32x4.mul(s,r))),SIMD.Float32x4.store(t,4,SIMD.Float32x4.sub(SIMD.Float32x4.mul(s,i),SIMD.Float32x4.mul(o,r))),t},i.rotateZ=r.USE_SIMD?i.SIMD.rotateZ:i.scalar.rotateZ,i.fromTranslation=function(t,e){return t[0]=1,t[1]=0,t[2]=0,t[3]=0,t[4]=0,t[5]=1,t[6]=0,t[7]=0,t[8]=0,t[9]=0,t[10]=1,t[11]=0,t[12]=e[0],t[13]=e[1],t[14]=e[2],t[15]=1,t},i.fromScaling=function(t,e){return t[0]=e[0],t[1]=0,t[2]=0,t[3]=0,t[4]=0,t[5]=e[1],t[6]=0,t[7]=0,t[8]=0,t[9]=0,t[10]=e[2],t[11]=0,t[12]=0,t[13]=0,t[14]=0,t[15]=1,t},i.fromRotation=function(t,e,n){var i,o,s,a=n[0],l=n[1],u=n[2],c=Math.sqrt(a*a+l*l+u*u);return Math.abs(c)<r.EPSILON?null:(a*=c=1/c,l*=c,u*=c,i=Math.sin(e),s=1-(o=Math.cos(e)),t[0]=a*a*s+o,t[1]=l*a*s+u*i,t[2]=u*a*s-l*i,t[3]=0,t[4]=a*l*s-u*i,t[5]=l*l*s+o,t[6]=u*l*s+a*i,t[7]=0,t[8]=a*u*s+l*i,t[9]=l*u*s-a*i,t[10]=u*u*s+o,t[11]=0,t[12]=0,t[13]=0,t[14]=0,t[15]=1,t)},i.fromXRotation=function(t,e){var n=Math.sin(e),r=Math.cos(e);return t[0]=1,t[1]=0,t[2]=0,t[3]=0,t[4]=0,t[5]=r,t[6]=n,t[7]=0,t[8]=0,t[9]=-n,t[10]=r,t[11]=0,t[12]=0,t[13]=0,t[14]=0,t[15]=1,t},i.fromYRotation=function(t,e){var n=Math.sin(e),r=Math.cos(e);return t[0]=r,t[1]=0,t[2]=-n,t[3]=0,t[4]=0,t[5]=1,t[6]=0,t[7]=0,t[8]=n,t[9]=0,t[10]=r,t[11]=0,t[12]=0,t[13]=0,t[14]=0,t[15]=1,t},i.fromZRotation=function(t,e){var n=Math.sin(e),r=Math.cos(e);return t[0]=r,t[1]=n,t[2]=0,t[3]=0,t[4]=-n,t[5]=r,t[6]=0,t[7]=0,t[8]=0,t[9]=0,t[10]=1,t[11]=0,t[12]=0,t[13]=0,t[14]=0,t[15]=1,t},i.fromRotationTranslation=function(t,e,n){var r=e[0],i=e[1],o=e[2],s=e[3],a=r+r,l=i+i,u=o+o,c=r*a,h=r*l,f=r*u,d=i*l,p=i*u,g=o*u,m=s*a,_=s*l,v=s*u;return t[0]=1-(d+g),t[1]=h+v,t[2]=f-_,t[3]=0,t[4]=h-v,t[5]=1-(c+g),t[6]=p+m,t[7]=0,t[8]=f+_,t[9]=p-m,t[10]=1-(c+d),t[11]=0,t[12]=n[0],t[13]=n[1],t[14]=n[2],t[15]=1,t},i.getTranslation=function(t,e){return t[0]=e[12],t[1]=e[13],t[2]=e[14],t},i.getRotation=function(t,e){var n=e[0]+e[5]+e[10],r=0;return n>0?(r=2*Math.sqrt(n+1),t[3]=.25*r,t[0]=(e[6]-e[9])/r,t[1]=(e[8]-e[2])/r,t[2]=(e[1]-e[4])/r):e[0]>e[5]&e[0]>e[10]?(r=2*Math.sqrt(1+e[0]-e[5]-e[10]),t[3]=(e[6]-e[9])/r,t[0]=.25*r,t[1]=(e[1]+e[4])/r,t[2]=(e[8]+e[2])/r):e[5]>e[10]?(r=2*Math.sqrt(1+e[5]-e[0]-e[10]),t[3]=(e[8]-e[2])/r,t[0]=(e[1]+e[4])/r,t[1]=.25*r,t[2]=(e[6]+e[9])/r):(r=2*Math.sqrt(1+e[10]-e[0]-e[5]),t[3]=(e[1]-e[4])/r,t[0]=(e[8]+e[2])/r,t[1]=(e[6]+e[9])/r,t[2]=.25*r),t},i.fromRotationTranslationScale=function(t,e,n,r){var i=e[0],o=e[1],s=e[2],a=e[3],l=i+i,u=o+o,c=s+s,h=i*l,f=i*u,d=i*c,p=o*u,g=o*c,m=s*c,_=a*l,v=a*u,b=a*c,x=r[0],y=r[1],w=r[2];return t[0]=(1-(p+m))*x,t[1]=(f+b)*x,t[2]=(d-v)*x,t[3]=0,t[4]=(f-b)*y,t[5]=(1-(h+m))*y,t[6]=(g+_)*y,t[7]=0,t[8]=(d+v)*w,t[9]=(g-_)*w,t[10]=(1-(h+p))*w,t[11]=0,t[12]=n[0],t[13]=n[1],t[14]=n[2],t[15]=1,t},i.fromRotationTranslationScaleOrigin=function(t,e,n,r,i){var o=e[0],s=e[1],a=e[2],l=e[3],u=o+o,c=s+s,h=a+a,f=o*u,d=o*c,p=o*h,g=s*c,m=s*h,_=a*h,v=l*u,b=l*c,x=l*h,y=r[0],w=r[1],k=r[2],S=i[0],M=i[1],T=i[2];return t[0]=(1-(g+_))*y,t[1]=(d+x)*y,t[2]=(p-b)*y,t[3]=0,t[4]=(d-x)*w,t[5]=(1-(f+_))*w,t[6]=(m+v)*w,t[7]=0,t[8]=(p+b)*k,t[9]=(m-v)*k,t[10]=(1-(f+g))*k,t[11]=0,t[12]=n[0]+S-(t[0]*S+t[4]*M+t[8]*T),t[13]=n[1]+M-(t[1]*S+t[5]*M+t[9]*T),t[14]=n[2]+T-(t[2]*S+t[6]*M+t[10]*T),t[15]=1,t},i.fromQuat=function(t,e){var n=e[0],r=e[1],i=e[2],o=e[3],s=n+n,a=r+r,l=i+i,u=n*s,c=r*s,h=r*a,f=i*s,d=i*a,p=i*l,g=o*s,m=o*a,_=o*l;return t[0]=1-h-p,t[1]=c+_,t[2]=f-m,t[3]=0,t[4]=c-_,t[5]=1-u-p,t[6]=d+g,t[7]=0,t[8]=f+m,t[9]=d-g,t[10]=1-u-h,t[11]=0,t[12]=0,t[13]=0,t[14]=0,t[15]=1,t},i.frustum=function(t,e,n,r,i,o,s){var a=1/(n-e),l=1/(i-r),u=1/(o-s);return t[0]=2*o*a,t[1]=0,t[2]=0,t[3]=0,t[4]=0,t[5]=2*o*l,t[6]=0,t[7]=0,t[8]=(n+e)*a,t[9]=(i+r)*l,t[10]=(s+o)*u,t[11]=-1,t[12]=0,t[13]=0,t[14]=s*o*2*u,t[15]=0,t},i.perspective=function(t,e,n,r,i){var o=1/Math.tan(e/2),s=1/(r-i);return t[0]=o/n,t[1]=0,t[2]=0,t[3]=0,t[4]=0,t[5]=o,t[6]=0,t[7]=0,t[8]=0,t[9]=0,t[10]=(i+r)*s,t[11]=-1,t[12]=0,t[13]=0,t[14]=2*i*r*s,t[15]=0,t},i.perspectiveFromFieldOfView=function(t,e,n,r){var i=Math.tan(e.upDegrees*Math.PI/180),o=Math.tan(e.downDegrees*Math.PI/180),s=Math.tan(e.leftDegrees*Math.PI/180),a=Math.tan(e.rightDegrees*Math.PI/180),l=2/(s+a),u=2/(i+o);return t[0]=l,t[1]=0,t[2]=0,t[3]=0,t[4]=0,t[5]=u,t[6]=0,t[7]=0,t[8]=-(s-a)*l*.5,t[9]=(i-o)*u*.5,t[10]=r/(n-r),t[11]=-1,t[12]=0,t[13]=0,t[14]=r*n/(n-r),t[15]=0,t},i.ortho=function(t,e,n,r,i,o,s){var a=1/(e-n),l=1/(r-i),u=1/(o-s);return 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i=Number.NEGATIVE_INFINITY,o=Number.POSITIVE_INFINITY;for(let t=0;t<r.length;t++)i=Math.max(r[t],i),o=Math.min(r[t],o);return this.getHorzZoomToFitCols(t,o,i+1)}getMinHorzZoom(){return Math.min(N/this.getOncoprintWidth(!0),1)}getMinVertZoom(){return this.max_height<Number.POSITIVE_INFINITY?this.max_height/this.getOncoprintHeight(!0):1}setHorzScroll(t){return this.horz_scroll=Math.max(0,t),this.horz_scroll}setVertScroll(t){return this.vert_scroll=Math.max(0,t),this.vert_scroll}setScroll(t,e){this.setHorzScroll(t),this.setVertScroll(e)}getHorzScroll(){return this.horz_scroll}getVertScroll(){return this.vert_scroll}setZoom(t,e){this.setHorzZoom(t),this.setVertZoom(e)}setCellPaddingOffBecauseOfZoom(t){this.cell_padding_off_because_of_zoom=t,this.column_left.update()}setHorzZoom(t){const e=this.getMinHorzZoom();return this.horz_zoom=F(t,e,1),this.column_left.update(),this.getCellWidth()<this.cell_padding_off_cell_width_threshold&&!this.cell_padding_off_because_of_zoom?this.setCellPaddingOffBecauseOfZoom(!0):this.getCellWidth()>=this.cell_padding_off_cell_width_threshold&&this.cell_padding_off_because_of_zoom&&this.setCellPaddingOffBecauseOfZoom(!1),this.horz_zoom}getVertZoom(){return this.vert_zoom}setVertZoom(t){const e=this.getMinVertZoom();return this.vert_zoom=F(t,e,1),this.track_tops.update(),this.vert_zoom}setShowTrackLabels(t){this.show_track_labels=t}getShowTrackLabels(){return this.show_track_labels}hideTrackLegends(t){t=[].concat(t);for(let e=0;e<t.length;e++)this.getRuleSet(t[e]).exclude_from_legend=!0}showTrackLegends(t){t=[].concat(t);for(let e=0;e<t.length;e++)this.getRuleSet(t[e]).exclude_from_legend=!1}clearTrackActiveRules(t){const e=this.track_rule_set_id[t],n=this.track_active_rules[t],r=this.rule_set_active_rules[e],i=Object.keys(n).map(t=>parseInt(t,10));for(let t=0;t<i.length;t++){const e=i[t];r.hasOwnProperty(e)&&(r[e]-=1,r[e]<=0&&delete r[e])}this.track_active_rules[t]={}}setTrackActiveRules(t,e){this.clearTrackActiveRules(t),this.track_active_rules[t]=e;const n=this.track_rule_set_id[t],r=this.rule_set_active_rules[n],i=Object.keys(e).map(t=>parseInt(t,0));for(let t=0;t<i.length;t++){const e=i[t];r[e]=r[e]||0,r[e]+=1}}getTrackUniversalShapes(t,e){const n=this.getRuleSet(t),r=this.getTrackHasColumnSpacing(t),i=this.getCellWidth(e)+(r?0:this.getCellPadding(e,!0)),o=this.getCellHeight(t,e);return n.getUniversalShapes(i,o)}getSpecificShapesForData(t,e){const n={},r=this.getTrackData(t),i=this.getTrackDataIdKey(t),o=this.getTrackHasColumnSpacing(t),s=this.getCellWidth(e)+(o?0:this.getCellPadding(e,!0)),a=this.getRuleSet(t).getSpecificShapesForDatum(r,s,this.getCellHeight(t,e),n,i,this.getTrackImportantIds(t));return this.setTrackActiveRules(t,n),a.map((function(t,e){return{id:r[e][i],shape_list:t}}))}getActiveRules(t){const e=this.rule_set_active_rules[t];return e?this.rule_sets[t].getSpecificRulesForDatum().filter((function(t){return!!e[t.id]})):[]}setTrackImportantIds(t,e){this.track_important_ids[t]=e?e.reduce((function(t,e){return t[e]=!0,t}),{}):void 0}getTrackImportantIds(t){return this.track_important_ids[t]}getRuleSets(){const t=this,e=this.getTrackGroupLegendOrder(),n={},r=this.getTrackGroups(),i=[];for(let t=0;t<e.length;t++)n[e[t]]=!0,r[e[t]]&&i.push(r[e[t]]);for(let t=0;t<r.length;t++)!n[t]&&r[t]&&i.push(r[t]);return function(t){const e={},n=[];for(let r=0;r<t.length;r++)void 0===e[t[r]]&&(e[t[r]]=!0,n.push(t[r]));return n}(i.reduce((function(t,e){return t.concat(e.tracks)}),[]).map((function(e){return t.track_rule_set_id[e]})).map(t=>t.toString())).map((function(e){return t.rule_sets[parseInt(e,10)]}))}getTrackHasColumnSpacing(t){return!!this.track_has_column_spacing[t]}getGapSize(){return this.getCellWidth(!0)}getCellWidth(t){return this.cell_width*(t?1:this.horz_zoom)}getCellHeight(t,e){return this.cell_height[t]*(e?1:this.vert_zoom)}getTrackInfo(t){return this.track_info[t]}setTrackInfo(t,e){this.track_info[t]=e}getTrackHeight(t,e){return this.getCellHeight(t,e)+2*this.getTrackPadding(t,e)}getTrackPadding(t,e){return this.track_padding[t]*(e?1:this.vert_zoom)}getBottomPadding(){return this.bottom_padding}getTrackSortDirection(t){return this.track_sort_direction[t]}setTrackSortDirection(t,e,n){this.track_sort_direction[t]=e,n||this.track_sort_direction_change_callback[t](t,e),this.precomputed_comparator.update(this,t)}resetSortableTracksSortDirection(t){const e=this.getTracks();for(const n of e)this.isTrackSortDirectionChangeable(n)&&this.setTrackSortDirection(n,0,t)}setCellPaddingOn(t){this.cell_padding_on=t,this.column_left.update()}getIdOrder(t){return t?this.id_order:this.visible_id_order.get()}getClosestColumnIndexToLeft(t,e,n){const r=e?this.getZoomedColumnLeft():this.getColumnLeft(),o=this.getIdOrder(),s=o[o.length-1];if(t>r[s]+this.getCellWidth())return o.length;if(t<r[o[0]])return 0;{const e=i(o,t,t=>r[t],!0),s=o[e],a=r[s];return n&&t!==a?e+1:e}}getIdToIndexMap(){return this.id_to_index.get()}getVisibleIdToIndexMap(){return this.visible_id_to_index.get()}getHiddenIds(){const t=this.hidden_ids;return this.id_order.filter((function(e){return!!t[e]}))}isSortAffected(t,e){let n;t=[].concat(t);const r=this;return n="track"===e?t.map((function(t){return r.getContainingTrackGroupIndex(t)})):t,"cluster"!==this.sort_config.type||n.indexOf(this.sort_config.track_group_index)>-1}setIdOrder(t){this.id_order=t.slice(),Object.freeze(this.id_order),this.id_to_index.update(),this.visible_id_order.update(this),this.column_left.update()}hideIds(t,e){e&&(this.hidden_ids={});for(let e=0,n=t.length;e<n;e++)this.hidden_ids[t[e]]=!0;this.visible_id_order.update(this),this.column_left.update()}setHighlightedTracks(t){this.highlighted_tracks=t}getHighlightedTracks(){const t=C.a.keyBy(this.getTracks());return this.highlighted_tracks.filter(e=>e in t)}setHighlightedIds(t){this.highlighted_ids=t}getVisibleHighlightedIds(){const t=this.getVisibleIdToIndexMap();return this.highlighted_ids.filter(e=>e in t)}restoreClusteredTrackGroupOrder(){if("cluster"===this.sort_config.type&&this.unclustered_track_group_order){const t=this.sort_config.track_group_index;this.setTrackGroupOrder(t,this.unclustered_track_group_order)}this.unclustered_track_group_order=void 0}setTrackGroupOrder(t,e){this.track_groups[t].tracks=e,this.track_tops.update()}moveTrackGroup(t,e){const n=[],r=this.track_groups[t];for(let i=0;i<this.track_groups.length;i++)i!==t&&i!==e&&n.push(this.track_groups[i]),i===e&&n.push(r);return this.track_groups=n,this.track_tops.update(),this.track_groups}addTracks(t){return L(this,void 0,void 0,(function*(){for(let e=0;e<t.length;e++){const n=t[e];this.addTrack(n)}0===this.rendering_suppressed_depth&&this.keep_sorted&&(yield this.sort()),this.track_tops.update()}))}addTrack(t){const e=t.track_id;this.$track_info_tooltip_elt[e]=t.$track_info_tooltip_elt,this.track_custom_options[e]=p(t.custom_track_options,[]),this.track_label[e]=p(t.label,"Label"),this.track_sublabel[e]=p(t.sublabel,""),this.track_label_color[e]=p(t.track_label_color,"black"),this.track_label_circle_color[e]=t.track_label_circle_color,this.track_label_font_weight[e]=t.track_label_font_weight,this.track_label_left_padding[e]=p(t.track_label_left_padding,0),this.track_link_url[e]=p(t.link_url,null),this.track_description[e]=p(t.description,""),this.cell_height[e]=p(t.cell_height,23),this.track_padding[e]=p(t.track_padding,5),this.track_has_column_spacing[e]=p(t.has_column_spacing,!0),this.track_tooltip_fn[e]=p(t.tooltipFn,(function(t){return t+""})),this.track_movable[e]=p(t.movable,!0),this.track_removable[e]=p(t.removable,!1),this.track_remove_callback[e]=p(t.removeCallback,(function(){})),this.track_remove_option_callback[e]=p(t.onClickRemoveInTrackMenu,(function(){})),void 0!==t.expandCallback&&(this.track_expand_callback[e]=t.expandCallback,this.track_expansion_enabled[e]=!0),void 0!==t.expandButtonTextGetter&&(this.track_expand_button_getter[e]=t.expandButtonTextGetter),this.track_can_show_gaps[e]=p(t.track_can_show_gaps,!1),this.track_show_gaps[e]=!1,this.track_sort_cmp_fn[e]=t.sortCmpFn,this.track_sort_direction_changeable[e]=p(t.sort_direction_changeable,!1),this.track_sort_direction_change_callback[e]=p(t.onSortDirectionChange,(function(){})),this.track_data[e]=p(t.data,[]),this.track_data_id_key[e]=p(t.data_id_key,"id"),this.track_info[e]=p(t.track_info,""),void 0!==t.html_label&&(this.track_html_label[e]=t.html_label),void 0!==t.rule_set&&(this.rule_sets[t.rule_set.rule_set_id]=t.rule_set,this.rule_set_active_rules[t.rule_set.rule_set_id]={},this.track_rule_set_id[e]=t.rule_set.rule_set_id),this.track_active_rules[e]={},t.important_ids&&this.setTrackImportantIds(e,t.important_ids),this.track_sort_direction[e]=p(t.init_sort_direction,1),t.target_group=p(t.target_group,0),this.ensureTrackGroupExists(t.target_group);const n=[this.track_groups[t.target_group].tracks];"cluster"===this.sort_config.type&&this.sort_config.track_group_index===t.target_group&&n.push(this.unclustered_track_group_order);for(const r of n){const n=void 0!==t.expansion_of?r.indexOf(this.getLastExpansion(t.expansion_of))+1:r.length;r.splice(n,0,e)}if(void 0!==t.expansion_of){if(this.track_expansion_tracks.hasOwnProperty(t.expansion_of)||(this.track_expansion_tracks[t.expansion_of]=[]),-1!==this.track_expansion_tracks[t.expansion_of].indexOf(e))throw new Error("Illegal state: duplicate expansion track ID");this.track_expansion_parent[e]=t.expansion_of,this.track_expansion_tracks[t.expansion_of].push(e)}this.track_id_to_datum.update(this,e),this.track_present_ids.update(this,e),this.precomputed_comparator.update(this,e)}getAllIds(){return Object.keys(this.present_ids.get())}releaseRendering(){return L(this,void 0,void 0,(function*(){this.keep_sorted?yield this.sort():this.setIdOrder(Object.keys(this.present_ids.get())),this.track_tops.update()}))}ensureTrackGroupExists(t){for(;t>=this.track_groups.length;)this.track_groups.push({tracks:[]})}_getMajorTrackGroup(t,e){let n,r;for(r=0;r<this.track_groups.length;r++)if(this.track_groups[r].tracks.indexOf(t)>-1){n=this.track_groups[r];break}return n?e?r:n:null}_getEffectiveTrackGroupTracks(t){const e=this;let n,r=this.track_expansion_parent[t];var i;return(n=void 0===r?null===(i=this._getMajorTrackGroup(t))?null:i.tracks.filter((function(t){return void 0===e.track_expansion_parent[t]})):this.track_expansion_tracks[r])?n.slice():null}isRuleSetUsed(t){let e=!1;const n=this.getTracks();for(let r=0;r<n.length;r++)if(this.track_rule_set_id[n[r]]===t){e=!0;break}return e}removeRuleSet(t){delete this.rule_sets[t],delete this.rule_set_active_rules[t]}removeTrack(t){const e=this.track_rule_set_id[t];this.clearTrackActiveRules(t),this.track_remove_callback[t](t),delete this.track_data[t],delete this.track_rule_set_id[t],delete this.track_label[t],delete this.track_link_url[t],delete this.cell_height[t],delete this.track_padding[t],delete this.track_data_id_key[t],delete this.track_tooltip_fn[t],delete this.track_movable[t],delete this.track_removable[t],delete this.track_remove_callback[t],delete this.track_sort_cmp_fn[t],delete this.track_sort_direction_changeable[t],delete this.track_sort_direction[t],delete this.track_info[t],delete this.track_has_column_spacing[t],delete this.track_expansion_enabled[t],delete this.track_expand_callback[t],delete this.track_expand_button_getter[t],delete this.track_expansion_tracks[t],delete this.track_label_circle_color[t],delete this.track_label_font_weight[t],delete this.track_label_left_padding[t];const n=this._getMajorTrackGroup(t);null!==n&&n.tracks.splice(n.tracks.indexOf(t),1);const r=this.track_expansion_tracks[this.track_expansion_parent[t]];r&&r.splice(r.indexOf(t),1),this.unclustered_track_group_order&&this.unclustered_track_group_order.indexOf(t)>-1&&this.unclustered_track_group_order.splice(this.unclustered_track_group_order.indexOf(t),1),delete this.track_expansion_parent[t],this.track_tops.update(),this.track_present_ids.update(this,t),this.track_id_to_datum.update(this,t),this.ids_after_a_gap.update(this),this.setIdOrder(Object.keys(this.present_ids.get())),this.isRuleSetUsed(e)||this.removeRuleSet(e)}getOverlappingCells(t,e){const n=this.getIdOrder(),r=this.getZoomedColumnLeft(),o=i(n,t,(function(t){return r[t]}),!0);if(-1===o)return null;const s=this.getTracks(),a=this.getCellTops(),l=i(s,e,(function(t){return a[t]}),!0);if(-1===l)return null;const u=s[l];if(e>=a[u]+this.getCellHeight(u))return null;const c=[];let h=this.getCellWidth();this.getTrackHasColumnSpacing(u)||(h+=this.getCellPadding());for(let e=o;e<n.length;e++)if(d([r[n[e]],r[n[e]]+h],t))c.push(n[e]);else if(r[n[e]]>t+1)break;return c.length>0?{ids:c,track:u,top:a[u],left:r[c[0]]}:null}getTrackDatum(t,e){const n=this.track_id_to_datum.get()[t];return n&&n[e]||null}getTrackTops(t){return void 0===t?O(this.track_tops.get()):this.track_tops.get()[t]}getZoomedTrackTops(t){return void 0===t?O(this.track_tops_zoomed.get()):this.track_tops_zoomed.get()[t]}getZoomedHeaderTops(t){return void 0===t?O(this.header_tops_zoomed.get()):this.header_tops_zoomed.get()[t]}getCellTops(t,e){return void 0===t?O((e?this.cell_tops:this.cell_tops_zoomed).get()):(e?this.cell_tops:this.cell_tops_zoomed).get()[t]}getLabelTops(t,e){return void 0===t?O((e?this.label_tops:this.label_tops_zoomed).get()):(e?this.label_tops:this.label_tops_zoomed).get()[t]}getContainingTrackGroup(t){return this._getEffectiveTrackGroupTracks(t)}getContainingTrackGroupIndex(t){return this._getMajorTrackGroup(t,!0)}getTrackGroups(){return this.track_groups}getTracks(){const t=[];for(let e=0;e<this.track_groups.length;e++)t.push(...this.track_groups[e].tracks);return t}getColumnLeft(t){return void 0===t?this.column_left.get():this.column_left.get()[t]}getColumnLeftNoPadding(t){return void 0===t?this.column_left_no_padding.get():this.column_left_no_padding.get()[t]}getZoomedColumnLeft(t){return void 0===t?this.zoomed_column_left.get():this.zoomed_column_left.get()[t]}getOncoprintHeight(t){const e=this.getTracks(),n=e[e.length-1];return(t?this.getTrackTops(n):this.getZoomedTrackTops(n))+this.getTrackHeight(n,t)+this.getBottomPadding()}getOncoprintWidth(t){const e=this.getIdOrder(),n=e[e.length-1];return(t?this.getColumnLeft(n):this.getZoomedColumnLeft(n))+this.getCellWidth(t)+1}getOncoprintWidthNoColumnPaddingNoGaps(){return this.getIdOrder().length*this.getCellWidth(!0)}getColumnLabels(){return this.column_labels}setColumnLabels(t){this.column_labels=t}moveTrack(t,e){function n(t,e,n,r){const i=t.indexOf(e),o=t.indexOf(n),s=t.slice(i,o+1);t.splice(i,s.length);const a=null===r?0:t.indexOf(r)+1;t.splice.bind(t,a,0).apply(null,s)}const r=this._getMajorTrackGroup(t),i=this.track_expansion_parent[t];let o;null!==r&&(o=void 0!==i&&null===e?i:this.getLastExpansion(e),n(r.tracks,t,this.getLastExpansion(t),o)),void 0!==this.track_expansion_parent[t]&&n(this.track_expansion_tracks[i],t,t,e),this.track_tops.update()}getTrackLabel(t){return this.track_label[t]}getTrackSublabel(t){return this.track_sublabel[t]}getShowTrackSublabels(){return this.show_track_sublabels}setShowTrackSublabels(t){return this.show_track_sublabels=t}getTrackLabelColor(t){return this.track_label_color[t]}getTrackLabelCircleColor(t){return this.track_label_circle_color[t]}getTrackLabelFontWeight(t){return this.track_label_font_weight[t]}getTrackLabelLeftPadding(t){return this.track_label_left_padding[t]}getOptionalHtmlTrackLabel(t){return this.track_html_label[t]}getTrackLinkUrl(t){return this.track_link_url[t]}getTrackDescription(t){return this.track_description[t]}getTrackTooltipFn(t){return this.track_tooltip_fn[t]}setTrackTooltipFn(t,e){this.track_tooltip_fn[t]=e}getTrackDataIdKey(t){return this.track_data_id_key[t]}getTrackGroupPadding(t){return this.track_group_padding*(t?1:this.vert_zoom)}isTrackRemovable(t){return this.track_removable[t]}getTrackRemoveOptionCallback(t){return this.track_remove_option_callback[t]}isTrackSortDirectionChangeable(t){return this.track_sort_direction_changeable[t]}isTrackExpandable(t){return Boolean(this.track_expansion_enabled[t])}expandTrack(t){return this.track_expand_callback[t](t)}disableTrackExpansion(t){this.track_expansion_enabled[t]=!1}enableTrackExpansion(t){if(!this.track_expand_callback.hasOwnProperty(t))throw new Error("Track '"+t+"' has no expandCallback");this.track_expansion_enabled[t]=!0}isTrackExpanded(t){return this.track_expansion_tracks.hasOwnProperty(t)&&this.track_expansion_tracks[t].length>0}getExpandButtonText(t){const e=this;return function(t){return e.track_expand_button_getter[t]||function(t){return t?"Expand more":"Expand"}}(t)(this.isTrackExpanded(t))}isExpansionOf(t,e){return this.track_expansion_tracks.hasOwnProperty(e)&&-1!==this.track_expansion_tracks[e].indexOf(t)}getLastExpansion(t){let e=this.track_expansion_tracks[t];for(;e&&e.length;)t=e[e.length-1],e=this.track_expansion_tracks[t];return t}getTrackCustomOptions(t){return this.track_custom_options[t]}setTrackCustomOptions(t,e){this.track_custom_options[t]=e}setTrackInfoTooltip(t,e){this.$track_info_tooltip_elt[t]=e}$getTrackInfoTooltip(t){return this.$track_info_tooltip_elt[t]}getRuleSet(t){return this.rule_sets[this.track_rule_set_id[t]]}shareRuleSet(t,e){this.setTrackActiveRules(e,{});const n=this.track_rule_set_id[e];this.track_rule_set_id[e]=this.track_rule_set_id[t],this.isRuleSetUsed(n)||this.removeRuleSet(n)}setRuleSet(t,e){this.setTrackActiveRules(t,{});const n=this.track_rule_set_id[t];this.rule_sets[e.rule_set_id]=e,this.rule_set_active_rules[e.rule_set_id]={},this.track_rule_set_id[t]=e.rule_set_id,this.isRuleSetUsed(n)||this.removeRuleSet(n)}getTrackSortComparator(t){return this.track_sort_cmp_fn[t]}setTrackSortComparator(t,e){this.track_sort_cmp_fn[t]=e,this.precomputed_comparator.update(this,t)}getTrackData(t){return this.track_data[t]}clusterTrackGroup(t,e){const n=h(this.sort_config),r=this,i=new c.a.Deferred,o={},s=this.getTrackGroups()[t];let a=[];void 0!==s&&(a=this._getEffectiveTrackGroupTracks(s.tracks[0])||[]);for(let t=0;t<a.length;t++){const n=a[t],r=this.getTrackDataIdKey(n),i=this.getTrackData(n);for(let t=0;t<i.length;t++){const s=i[t][r],a=e(i[t]);o[s]=o[s]||{},o[s][n]=a}}return Object.keys(o).length?(c.a.when((u=o,l(u,"CASES")),function(t){return l(t,"ENTITIES")}(o)).then((function(e,o){if(!C.a.isEqual(r.sort_config,n))return;r.setIdOrder(e.map((function(t){return t.caseId})));const s=o.map((function(t){return parseInt(t.entityId,10)})),l=[];s.forEach((function(t){l.push(t),Array.prototype.push.apply(l,r.track_expansion_tracks[t]||[])})),r.unclustered_track_group_order||(r.unclustered_track_group_order=a),i.resolve({track_group_index:t,track_id_order:l})})).fail((function(){i.reject()})),i.promise()):i.resolve().promise();var u}setTrackData(t,e,n){this.track_data[t]=e,this.track_data_id_key[t]=n,this.track_id_to_datum.update(this,t),this.track_present_ids.update(this,t),this.setIdOrder(Object.keys(this.present_ids.get())),this.precomputed_comparator.update(this,t)}setTrackGroupLegendOrder(t){this.track_group_legend_order=t.slice()}getTrackGroupLegendOrder(){return this.track_group_legend_order}setTrackGroupSortPriority(t){this.track_group_sort_priority=t,this.sort()}sortAlphabetical(){const t=this.getIdOrder(!0).slice();t.sort((function(t,e){return t.localeCompare(e)})),this.setIdOrder(t)}sortByTracks(){const t=this.track_group_sort_priority,e=this.getTrackGroups();let n;const r=(n=t.length<e.length?e:t.map((function(t){return e[t]}))).reduce((function(t,e){return t.concat(e.tracks)}),[]),i=this.precomputed_comparator.get();function o(t){const e=[],n=[];for(let o=0;o<r.length;o++){const s=i[r[o]].getSortValue(t);e.push(s.mandatory),n.push(s.preferred)}return e.concat(n)}const s=k(this.getAllIds().map((function(t){return{id:t,vector:o(t)}})),(function(t){return t.vector}));this.setIdOrder(s.map((function(t){return t.id})))}sort(){const t=new c.a.Deferred;return this.sort_config=this.sort_config||{},"alphabetical"===this.sort_config.type?(this.sortAlphabetical(),t.resolve()):"order"===this.sort_config.type?(this.setIdOrder(this.sort_config.order),t.resolve()):"cluster"===this.sort_config.type?this.clusterTrackGroup(this.sort_config.track_group_index,this.sort_config.clusterValueFn).then((function(e){t.resolve(e)})):(this.sortByTracks(),t.resolve()),t.promise()}setSortConfig(t){"cluster"!==this.sort_config.type||"cluster"===t.type&&t.track_group_index===this.sort_config.track_group_index||this.restoreClusteredTrackGroupOrder(),this.sort_config=t}getTrackMovable(t){return 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uniform float texSize;\n            varying float texCoord;\n            \n            \n\n            vec3 getUnpackedPositionVec3() {\n            \tfloat pos0 = floor(aPosVertex / (positionBitPackBase * positionBitPackBase));\n            \tfloat pos0Contr = pos0 * positionBitPackBase * positionBitPackBase;\n            \tfloat pos1 = floor((aPosVertex - pos0Contr)/positionBitPackBase);\n            \tfloat pos1Contr = pos1 * positionBitPackBase;\n            \tfloat pos2 = aPosVertex - pos0Contr - pos1Contr;\n            \treturn vec3(pos0, pos1, pos2);\n            }\n\n            float getGapOffset() {\n                // first do binary search to compute the number of gaps before this column, G(c)\n                // G(c) = the index in columnsRightAfterGaps of the first entry thats greater than c\n                 \n                int lower_incl = 0;\n                int upper_excl = ${t};\n                int numGaps = 0;\n                \n                for (int loopDummyVar = 0; loopDummyVar == 0; loopDummyVar += 0) {\n                    if (lower_incl >= upper_excl) {\n                        break;\n                    }\n                \n                    int middle = (lower_incl + upper_excl)/2;\n                    if (columnsRightAfterGaps[middle] < aVertexOncoprintColumn) {\n                        // G(c) > middle\n                        lower_incl = middle + 1;\n                    } else if (columnsRightAfterGaps[middle] == aVertexOncoprintColumn) {\n                        // G(c) = middle + 1\n                        numGaps = middle + 1;\n                        break;\n                    } else {\n                        // columnsRightAfterGaps[middle] > column, so G(c) <= middle\n                        if (middle == 0) {\n                            // 0 <= G(c) <= 0 -> G(c) = 0\n                            numGaps = 0;\n                            break;\n                        } else if (columnsRightAfterGaps[middle-1] < aVertexOncoprintColumn) {\n                            // G(c) = middle\n                            numGaps = middle;\n                            break;\n                        } else {\n                            // columnsRightAfterGaps[middle-1] >= column, so G(c) <= middle-1\n                            upper_excl = middle;\n                        }\n                    }\n                }\n \n                // multiply it by the gap size to get the total offset\n                return float(numGaps)*gapSize;\n            }\n\n            void main(void) {\n            \tgl_Position = vec4(getUnpackedPositionVec3(), 1.0);\n            \tgl_Position[0] += aVertexOncoprintColumn*columnWidth;\n            \tgl_Position *= vec4(zoomX, zoomY, 1.0, 1.0);\n\n            // gaps should not be affected by zoom:\n                gl_Position[0] += getGapOffset();\n\n            // offsetY is given zoomed:\n            \tgl_Position[1] += offsetY;\n\n            \tgl_Position -= vec4(scrollX, scrollY, 0.0, 0.0);\n            \tgl_Position[0] *= supersamplingRatio;\n            \tgl_Position[1] *= supersamplingRatio;\n            \tgl_Position = uPMatrix * uMVMatrix * gl_Position;\n\n            \ttexCoord = (aColVertex + 0.5) / texSize;\n            }`}(e),"VERTEX_SHADER"),r=this.createShader("precision mediump float;\n            varying float texCoord;\n            uniform sampler2D uSampler;\n            void main(void) {\n                gl_FragColor = texture2D(uSampler, vec2(texCoord, 0.5));\n            }","FRAGMENT_SHADER"),i=this.createShaderProgram(n,r);i.vertexPositionAttribute=this.ctx.getAttribLocation(i,"aPosVertex"),this.ctx.enableVertexAttribArray(i.vertexPositionAttribute),i.vertexColorAttribute=this.ctx.getAttribLocation(i,"aColVertex"),this.ctx.enableVertexAttribArray(i.vertexColorAttribute),i.vertexOncoprintColumnAttribute=this.ctx.getAttribLocation(i,"aVertexOncoprintColumn"),this.ctx.enableVertexAttribArray(i.vertexOncoprintColumnAttribute),i.gapSizeUniform=this.ctx.getUniformLocation(i,"gapSize"),i.columnsRightAfterGapsUniform=this.ctx.getUniformLocation(i,"columnsRightAfterGaps"),i.samplerUniform=this.ctx.getUniformLocation(i,"uSampler"),i.pMatrixUniform=this.ctx.getUniformLocation(i,"uPMatrix"),i.mvMatrixUniform=this.ctx.getUniformLocation(i,"uMVMatrix"),i.columnWidthUniform=this.ctx.getUniformLocation(i,"columnWidth"),i.scrollXUniform=this.ctx.getUniformLocation(i,"scrollX"),i.scrollYUniform=this.ctx.getUniformLocation(i,"scrollY"),i.zoomXUniform=this.ctx.getUniformLocation(i,"zoomX"),i.zoomYUniform=this.ctx.getUniformLocation(i,"zoomY"),i.offsetYUniform=this.ctx.getUniformLocation(i,"offsetY"),i.supersamplingRatioUniform=this.ctx.getUniformLocation(i,"supersamplingRatio"),i.positionBitPackBaseUniform=this.ctx.getUniformLocation(i,"positionBitPackBase"),i.texSizeUniform=this.ctx.getUniformLocation(i,"texSize"),this.shader_program=i}resizeAndClear(t){const e=this.getVisibleAreaHeight(t),n=this.getTotalWidth(t),r=this.visible_area_width;this.$dummy_scroll_div_contents.css({"min-width":n,"min-height":t.getOncoprintHeight()}),this.$dummy_scroll_div_contents.parent().css({height:e+20,width:r+20}),this.dummy_scroll_div_client_size.update(),this.$canvas[0].height=this.supersampling_ratio*e,this.$canvas[0].style.height=e+"px",this.$overlay_canvas[0].height=this.supersampling_ratio*e,this.$overlay_canvas[0].style.height=e+"px",this.$column_label_canvas[0].height=this.supersampling_ratio*e,this.$column_label_canvas[0].style.height=e+"px",this.$canvas[0].width=this.supersampling_ratio*r,this.$canvas[0].style.width=r+"px",this.$overlay_canvas[0].width=this.supersampling_ratio*r,this.$overlay_canvas[0].style.width=r+"px",this.$column_label_canvas[0].width=this.supersampling_ratio*r,this.$column_label_canvas[0].style.width=r+"px",this.$container.css("height",e),this.$container.css("width",r),this.getWebGLContextAndSetUpMatrices(),this.setUpShaders(t),this.getOverlayContextAndClear(),this.getColumnLabelsContext()}renderAllTracks(t,e){if(this.rendering_suppressed)return;const n=this.scroll_x,r=this.scroll_y,i=t.getHorzZoom(),o=t.getVertZoom(),s=this.getViewportOncoprintSpace(t),a=s.left,l=s.right,u=s.top,c=s.bottom,h=t.getIdOrder();let f=t.getClosestColumnIndexToLeft(a);const d=t.getClosestColumnIndexToLeft(l,!1,!0),p=h[f=f<1?0:f-1],g=-1===d||d===h.length?null:h[d];e||this.resizeAndClear(t),this.ctx.clearColor(1,1,1,1),this.ctx.clear(this.ctx.COLOR_BUFFER_BIT|this.ctx.DEPTH_BUFFER_BIT);const m=t.getTracks();for(let e=0;e<m.length;e++){const s=m[e],a=t.getCellTops(s),l=t.getCellHeight(s);if(a/o>=c||(a+l)/o<u)continue;const h=this.getTrackBuffers(s);if(0!==h.position.numItems)for(const e of[!1,!0]){const l=this.shader_program;if(this.ctx.useProgram(l),e)this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,h.position),this.ctx.vertexAttribPointer(l.vertexPositionAttribute,h.position.itemSize,this.ctx.FLOAT,!1,0,0),this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,h.color),this.ctx.vertexAttribPointer(l.vertexColorAttribute,h.color.itemSize,this.ctx.FLOAT,!1,0,0),this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,h.column),this.ctx.vertexAttribPointer(l.vertexOncoprintColumnAttribute,h.column.itemSize,this.ctx.FLOAT,!1,0,0),this.ext.vertexAttribDivisorANGLE(l.vertexOncoprintColumnAttribute,0);else{const t=h.position.specificShapesNumItems*h.position.itemSize;this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,h.position),this.ctx.vertexAttribPointer(l.vertexPositionAttribute,h.position.itemSize,this.ctx.FLOAT,!1,0,4*t),this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,h.color),this.ctx.vertexAttribPointer(l.vertexColorAttribute,h.color.itemSize,this.ctx.FLOAT,!1,0,4*t),this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,this.simple_count_buffer),this.ctx.vertexAttribPointer(l.vertexOncoprintColumnAttribute,1,this.ctx.FLOAT,!1,0,4*f),this.ext.vertexAttribDivisorANGLE(l.vertexOncoprintColumnAttribute,1)}if(this.ctx.activeTexture(this.ctx.TEXTURE0),this.ctx.bindTexture(this.ctx.TEXTURE_2D,h.color_tex.texture),this.ctx.uniform1i(l.samplerUniform,0),this.ctx.uniform1f(l.texSizeUniform,h.color_tex.size),this.ctx.uniform1fv(l.columnsRightAfterGapsUniform,this.getColumnIndexesAfterAGap(t)),this.ctx.uniform1f(l.gapSizeUniform,t.getGapSize()),this.ctx.uniformMatrix4fv(l.pMatrixUniform,!1,this.pMatrix),this.ctx.uniformMatrix4fv(l.mvMatrixUniform,!1,this.mvMatrix),this.ctx.uniform1f(l.columnWidthUniform,t.getCellWidth(!0)+t.getCellPadding(!0)),this.ctx.uniform1f(l.scrollXUniform,n),this.ctx.uniform1f(l.scrollYUniform,r),this.ctx.uniform1f(l.zoomXUniform,i),this.ctx.uniform1f(l.zoomYUniform,o),this.ctx.uniform1f(l.offsetYUniform,a),this.ctx.uniform1f(l.supersamplingRatioUniform,this.supersampling_ratio),this.ctx.uniform1f(l.positionBitPackBaseUniform,this.position_bit_pack_base),e){const t=this.id_to_first_vertex_index[s][p],e=null===g?h.position.specificShapesNumItems:this.id_to_first_vertex_index[s][g];this.ctx.drawArrays(this.ctx.TRIANGLES,t,e-t)}else this.ext.drawArraysInstancedANGLE(this.ctx.TRIANGLES,0,h.position.itemSize*h.position.universalShapesNumItems,d-f)}}this.ctx.flush(),this.renderColumnLabels(t,h.slice(f,-1===d?void 0:d)),this.clearOverlay(),this.highlightHighlightedIds(t),this.highlightHighlightedTracks(t)}static getColumnLabelsFontSize(t){return t.getCellWidth()/2+2}prepareContextForColumnLabelText(t,e){const n=ct.getColumnLabelsFontSize(t);e.font=this.supersampling_ratio*n+"px Arial",e.textAlign="left",e.textBaseline="middle"}renderColumnLabels(t,e){this.column_label_ctx.fillStyle="rgba(0,0,0,0)",this.column_label_ctx.clearRect(0,0,this.$column_label_canvas[0].width,this.$column_label_canvas[0].height),this.maximum_column_label_width=0,this.maximum_column_label_height=0;const n=t.getColumnLabels();if(0===Object.keys(n).length)return;const r=this.getColumnLabelY(t),i=t.getZoomedColumnLeft(),o=this.scroll_x,s=t.getCellWidth();this.prepareContextForColumnLabelText(t,this.column_label_ctx);for(let a=0;a<e.length;a++){const l=n[e[a]];let u=this.column_label_ctx.measureText("m").width/this.supersampling_ratio;if(l){const n=(i[e[a]]+s/2-o)*this.supersampling_ratio;if(l.circle_color){this.column_label_ctx.save();const e=this.getColumnLabelCircleSpec(t);u=Math.max(2*e.radius,u),this.column_label_ctx.translate(n,r),this.column_label_ctx.fillStyle=l.circle_color,this.column_label_ctx.beginPath(),this.column_label_ctx.arc(0,0,this.supersampling_ratio*e.radius,0,2*Math.PI),this.column_label_ctx.fill(),this.column_label_ctx.restore()}this.column_label_ctx.save();const c=this.getColumnLabelAngleRadians(l),h=(l.left_padding_percent||0)*s/100;this.column_label_ctx.translate(n,r),this.column_label_ctx.rotate(c),this.column_label_ctx.fillStyle=l.text_color||"rgba(0,0,0,1)",this.column_label_ctx.fillText(l.text,h*this.supersampling_ratio,0);const f=this.column_label_ctx.measureText(l.text).width/this.supersampling_ratio;this.maximum_column_label_width=Math.max(this.maximum_column_label_width,Math.cos(c)*f),this.maximum_column_label_height=Math.max(this.maximum_column_label_height,Math.sin(c)*f,u),this.column_label_ctx.restore()}}}getColumnLabelAngleRadians(t){return p(t.angle_in_degrees,at)*Math.PI/180}getColumnLabelCircleSpec(t){return{radius:t.getCellWidth()/2*.9}}ensureSimpleCountBuffer(t){const e=t.getIdOrder().length;if(!this.simple_count_buffer||this.simple_count_buffer.numItems!==e){const t=this.ctx.createBuffer();this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,t),this.ctx.bufferData(this.ctx.ARRAY_BUFFER,new Float32Array(C.a.range(0,e)),this.ctx.STATIC_DRAW),t.itemSize=1,t.numItems=e,this.simple_count_buffer=t}}clearTrackPositionAndColorBuffers(t,e){let n;n=void 0===e?t.getTracks():[e];for(let t=0;t<n.length;t++)this.is_buffer_empty[n[t]]&&(this.is_buffer_empty[n[t]].position=!0,this.is_buffer_empty[n[t]].color=!0,this.is_buffer_empty[n[t]].color_texture=!0)}clearTrackColumnBuffers(t,e){let n;n=void 0===e?t.getTracks():[e];for(let t=0;t<n.length;t++)this.is_buffer_empty[n[t]]&&(this.is_buffer_empty[n[t]].column=!0)}deleteBuffers(t,e){let n;n=void 0===e?t.getTracks():[e];for(let t=0;t<n.length;t++){const e=n[t];this.vertex_position_buffer[e]&&(this.ctx.deleteBuffer(this.vertex_position_buffer[e]),delete this.vertex_position_buffer[e]),this.vertex_color_buffer[e]&&(this.ctx.deleteBuffer(this.vertex_color_buffer[e]),delete this.vertex_color_buffer[e]),this.vertex_column_buffer[e]&&(this.ctx.deleteBuffer(this.vertex_column_buffer[e]),delete this.vertex_column_buffer[e]),this.color_texture[e]&&(this.ctx.deleteTexture(this.color_texture[e].texture),delete this.color_texture[e]),this.is_buffer_empty[e]={position:!0,color:!0,color_texture:!0,column:!0}}}deleteSimpleCountBuffer(t){this.simple_count_buffer&&(this.ctx.deleteBuffer(this.simple_count_buffer),this.simple_count_buffer=null)}getTrackBuffers(t){if(this.is_buffer_empty[t]=this.is_buffer_empty[t]||{position:!0,color:!0,color_texture:!0,column:!0},this.is_buffer_empty[t].position){const e=this.vertex_position_buffer[t]||this.ctx.createBuffer(),n=this.vertex_data[t].pos_array,r=this.vertex_data[t].universal_shapes_start_index;this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,e),this.ctx.bufferData(this.ctx.ARRAY_BUFFER,n,this.ctx.STATIC_DRAW),e.itemSize=1,e.specificShapesNumItems=r/e.itemSize,e.universalShapesNumItems=(n.length-r)/e.itemSize,this.vertex_position_buffer[t]=e}if(this.is_buffer_empty[t].color){const e=this.vertex_color_buffer[t]||this.ctx.createBuffer(),n=this.vertex_data[t].col_array,r=this.vertex_data[t].universal_shapes_start_index;this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,e),this.ctx.bufferData(this.ctx.ARRAY_BUFFER,n,this.ctx.STATIC_DRAW),e.itemSize=1,e.specificShapesNumItems=r/e.itemSize,e.universalShapesNumItems=(n.length-r)/e.itemSize,this.vertex_color_buffer[t]=e}if(this.is_buffer_empty[t].color_texture){const e=this.color_texture[t]?this.color_texture[t].texture:this.ctx.createTexture();this.ctx.bindTexture(this.ctx.TEXTURE_2D,e);const n=this.vertex_data[t].col_bank,r=Math.pow(2,Math.ceil(Math.log2(n.length/4)));for(;n.length<4*r;)n.push(0);const i=1;this.ctx.texImage2D(this.ctx.TEXTURE_2D,0,this.ctx.RGBA,r,i,0,this.ctx.RGBA,this.ctx.UNSIGNED_BYTE,new Uint8Array(n)),this.ctx.texParameteri(this.ctx.TEXTURE_2D,this.ctx.TEXTURE_MIN_FILTER,this.ctx.NEAREST),this.ctx.texParameteri(this.ctx.TEXTURE_2D,this.ctx.TEXTURE_MAG_FILTER,this.ctx.NEAREST),this.color_texture[t]={texture:e,size:r}}if(this.is_buffer_empty[t].column){const e=this.vertex_column_buffer[t]||this.ctx.createBuffer(),n=this.vertex_column_array[t];this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,e),this.ctx.bufferData(this.ctx.ARRAY_BUFFER,n,this.ctx.STATIC_DRAW),e.itemSize=1,e.numItems=n.length/e.itemSize,this.vertex_column_buffer[t]=e}return this.is_buffer_empty[t]={position:!1,color:!1,column:!1,color_texture:!1},{position:this.vertex_position_buffer[t],color:this.vertex_color_buffer[t],color_tex:this.color_texture[t],column:this.vertex_column_buffer[t]}}computeVertexColumns(t,e){if(this.rendering_suppressed)return;const n=this.vertex_data[e].pos_array.length,r=this.id_to_first_vertex_index[e],i=t.getVisibleIdToIndexMap(),o=Object.keys(r).map((function(t){return[t,r[t]]})).sort((function(t,e){return m(t[1],e[1])})),s=new Float32Array(n);let a=0;for(let t=0;t<o.length;t++){const e=(t===o.length-1?n:o[t+1][1])-o[t][1],r=i[o[t][0]];for(let t=0;t<e;t++)s[a]=r,a+=1}this.vertex_column_array[e]=s,this.clearTrackColumnBuffers(t,e)}computeVertexPositionsAndVertexColors(t,e){if(this.rendering_suppressed)return;this.ensureSimpleCountBuffer(t);const n=this.universal_shapes[e],r=t.getIdToIndexMap(),i=C.a.sortBy(this.specific_shapes[e],t=>r[t.id]),o=C.a.sumBy(i,t=>C.a.sumBy(t.shape_list,J))+(n?C.a.sumBy(n,J):0),s=new Float32Array(o),a=new Float32Array(o),l=C.a.clone(r),u=[],c={},h=this.position_bit_pack_base;const f={};let d=0;function p(t,e){const n=nt.hashComputedShape(t,e);if(!(n in f)){f[n]={position:[],color:[]};const r=f[n].position,i=f[n].color;X(t,e,(function(t,e){var n;t=t.map(Math.round),r.push(h*h*(n=t)[0]+h*n[1]+n[2]);const o=`${e[0]},${e[1]},${e[2]},${e[3]}`;let s=c[o];void 0===s&&(s=u.length,u.push(e),c[o]=s),i.push(s)}))}const r=f[n].position,i=f[n].color;for(let t=0;t<r.length;t++)s[d]=r[t],a[d]=i[t],d+=1}for(let t=0;t<i.length;t++){const e=i[t].shape_list;l[i[t].id]=d;for(let t=0;t<e.length;t++){p(e[t],t)}}const g=d;if(n)for(let t=0;t<n.length;t++){p(n[t],t)}const m=u.reduce((function(t,e){return t.concat(e)}),[]);0===m.length&&m.push(0,0,0,0),this.vertex_data[e]={pos_array:s,col_array:a,col_bank:m,universal_shapes_start_index:g},this.id_to_first_vertex_index[e]=l,this.clearTrackPositionAndColorBuffers(t,e)}getShapes(t,e){this.rendering_suppressed||(this.specific_shapes[e]=t.getSpecificShapesForData(e,!0),this.universal_shapes[e]=t.getTrackUniversalShapes(e,!0))}refreshCanvas(t){this.deleteBuffers(t),this.deleteSimpleCountBuffer(t),this.getNewCanvas(),this.getWebGLContextAndSetUpMatrices(),this.setUpShaders(t),this.ensureSimpleCountBuffer(t)}highlightCell(t,e,n){this.overlayStrokeRect(t.getZoomedColumnLeft(n)-this.scroll_x,t.getCellTops(e)-this.scroll_y,t.getCellWidth()+(t.getTrackHasColumnSpacing(e)?0:t.getCellPadding()),t.getCellHeight(e),"rgba(0,0,0,1)")}highlightTrack(t,e){const n=t.getCellWidth()+(t.getTrackHasColumnSpacing(e)?0:t.getCellPadding()),r=t.getCellHeight(e),i=t.getIdOrder(),o=t.getZoomedColumnLeft(),s=t.getCellTops(e)-this.scroll_y;for(const a of i)null!==t.getTrackDatum(e,a)&&a in o&&this.overlayStrokeRect(o[a]-this.scroll_x,s,n,r,ut)}highlightColumn(t,e){const n=t.getZoomedColumnLeft(e)-this.scroll_x,r=t.getCellPadding(),i=t.getCellWidth(),o=t.getTracks();for(let s=0;s<o.length;s++)null!==t.getTrackDatum(o[s],e)&&this.overlayStrokeRect(n,t.getCellTops(o[s])-this.scroll_y,i+(t.getTrackHasColumnSpacing(o[s])?0:r),t.getCellHeight(o[s]),ut);this.overlayColumnLabelHighlight(t,e)}getViewportOncoprintSpace(t){const e=this.scroll_y,n=t.getVertZoom(),r=t.getIdOrder(),i=t.getClosestColumnIndexToLeft(this.scroll_x,!0),o=r[i],s=t.getClosestColumnIndexToLeft(this.scroll_x+this.visible_area_width,!0,!0);let a;return a=s<r.length?t.getColumnLeft(r[s]):t.getColumnLeft(r[r.length-1])+t.getCellWidth(!0),{top:Math.round(e/n),bottom:Math.round((e+this.getVisibleAreaHeight(t))/n),left:t.getColumnLeft(o),right:a,center_col_index:Math.floor((s+i)/2)}}isUsable(){return null!==this.ctx}removeTrack(t,e){this.deleteBuffers(t,e),delete this.specific_shapes[e],delete this.vertex_data[e],delete this.vertex_column_array[e],delete this.id_to_first_vertex_index[e],delete this.is_buffer_empty[e],delete this.universal_shapes[e],this.rendering_suppressed||this.renderAllTracks(t)}moveTrack(t){this.rendering_suppressed||this.renderAllTracks(t)}setTrackGroupOrder(t){this.rendering_suppressed||this.renderAllTracks(t)}setTrackShowGaps(t){this.rendering_suppressed||(this.setUpShaders(t),this.renderAllTracks(t))}setColumnLabels(t){this.rendering_suppressed||this.renderAllTracks(t)}addTracks(t,e){if(!this.rendering_suppressed){for(let n=0;n<e.length;n++)this.getShapes(t,e[n]),this.computeVertexPositionsAndVertexColors(t,e[n]),this.computeVertexColumns(t,e[n]);this.renderAllTracks(t)}}setIdOrder(t,e){if(this.rendering_suppressed)return;const n=t.getTracks();for(let e=0;e<n.length;e++)this.computeVertexColumns(t,n[e]);this.renderAllTracks(t)}setTrackGroupSortPriority(t){this.rendering_suppressed||this.renderAllTracks(t)}sort(t){if(this.rendering_suppressed)return;const e=t.getTracks();for(let n=0;n<e.length;n++)this.computeVertexPositionsAndVertexColors(t,e[n]),this.computeVertexColumns(t,e[n]);this.renderAllTracks(t)}suppressRendering(){this.rendering_suppressed=!0}releaseRendering(t){this.rendering_suppressed=!1,this.updateAntialiasSetting(t);const e=t.getTracks();for(let n=0;n<e.length;n++)this.getShapes(t,e[n]),this.computeVertexPositionsAndVertexColors(t,e[n]),this.computeVertexColumns(t,e[n]);this.setUpShaders(t),this.renderAllTracks(t)}hideIds(t){if(this.rendering_suppressed)return;const e=t.getTracks();for(let n=0;n<e.length;n++)this.computeVertexColumns(t,e[n]);this.renderAllTracks(t)}setTrackImportantIds(t,e){this.rendering_suppressed||(this.getShapes(t,e),this.computeVertexPositionsAndVertexColors(t,e),this.computeVertexColumns(t,e),this.renderAllTracks(t))}setTrackData(t,e){this.rendering_suppressed||(this.getShapes(t,e),this.computeVertexPositionsAndVertexColors(t,e),this.computeVertexColumns(t,e),this.renderAllTracks(t))}setRuleSet(t,e){this.rendering_suppressed||(this.getShapes(t,e),this.computeVertexPositionsAndVertexColors(t,e),this.renderAllTracks(t))}shareRuleSet(t,e){this.rendering_suppressed||(this.getShapes(t,e),this.computeVertexPositionsAndVertexColors(t,e),this.renderAllTracks(t))}setSortConfig(t){this.rendering_suppressed||this.sort(t)}setHorzScroll(t){this.setScroll(t)}setVertScroll(t){this.setScroll(t)}setScroll(t){this.scroll_x=t.getHorzScroll(),this.scroll_y=t.getVertScroll(),this.rendering_suppressed||this.renderAllTracks(t,!0)}updateAntialiasSetting(t){t.getCellWidth()<this.antialias_on_cell_width_thresh?this.antialias||(this.antialias=!0,this.refreshCanvas(t)):this.antialias&&(this.antialias=!1,this.refreshCanvas(t))}setZoom(t){this.rendering_suppressed||(this.updateAntialiasSetting(t),this.renderAllTracks(t))}setHorzZoom(t){this.rendering_suppressed||(this.updateAntialiasSetting(t),this.renderAllTracks(t))}setVertZoom(t){this.rendering_suppressed||this.renderAllTracks(t)}setTrackGroupHeader(t){this.rendering_suppressed||this.renderAllTracks(t)}setViewport(t){this.scroll_x=t.getHorzScroll(),this.scroll_y=t.getVertScroll(),this.rendering_suppressed||(this.updateAntialiasSetting(t),this.renderAllTracks(t))}getTotalWidth(t,e){let n=t.getOncoprintWidth(e);return this.maximum_column_label_width>0&&(n+=this.maximum_column_label_width),n}getVisibleAreaWidth(){return this.visible_area_width}setWidth(t,e){this.visible_area_width=t,this.rendering_suppressed||this.renderAllTracks(e)}getColumnLabelsHeight(){let t=0;return this.maximum_column_label_height>0&&(t+=lt,t+=this.maximum_column_label_height),t}getTotalHeight(t){return t.getOncoprintHeight()+this.getColumnLabelsHeight()}getVisibleAreaHeight(t){return Math.min(t.getOncoprintHeight(),t.max_height)+this.getColumnLabelsHeight()}setCellPaddingOn(t){if(this.rendering_suppressed)return;const e=t.getTracks();for(let n=0;n<e.length;n++)t.getTrackHasColumnSpacing(e[n])||(this.getShapes(t,e[n]),this.computeVertexPositionsAndVertexColors(t,e[n])),this.computeVertexColumns(t,e[n]);this.renderAllTracks(t)}setHighlightedIds(t){this.clearOverlay(),this.highlightHighlightedIds(t),this.highlightHighlightedTracks(t)}setHighlightedTracks(t){this.clearOverlay(),this.highlightHighlightedIds(t),this.highlightHighlightedTracks(t)}highlightHighlightedIds(t,e){const n=t.getVisibleHighlightedIds();for(let r=0;r<n.length;r++)e&&-1!==e.indexOf(n[r])||this.highlightColumn(t,n[r])}highlightHighlightedTracks(t){const e=t.getHighlightedTracks();for(let n=0;n<e.length;n++)this.highlightTrack(t,e[n])}getDummyScrollDivClientSize(){return this.dummy_scroll_div_client_size.get()}toSVGGroup(t,e,n){const r=U.group(e||0,n||0),i=t.getCellTops(),o=t.getTracks(),s=t.getZoomedColumnLeft();for(let e=0;e<o.length;e++){const n=o[e],a=i[n],l=t.getTrackUniversalShapes(n,!1),u=t.getSpecificShapesForData(n,!1);for(let t=0;t<u.length;t++){const e=u[t],n=e.id,i=e.shape_list,o=s[n];if(void 0!==o){for(let t=0;t<l.length;t++)r.appendChild(U.fromShape(l[t],o,a));for(let t=0;t<i.length;t++)r.appendChild(U.fromShape(i[t],o,a))}}}const a=t.getColumnLabels(),l=t.getZoomedColumnLeft(),u=Object.keys(a),c=t.getOncoprintHeight()+10,h=ct.getColumnLabelsFontSize(t),f=t.getCellWidth();for(let e=0;e<u.length;e++){const n=u[e];if(!(n in l))continue;const i=a[n],o=l[n]+f/2;if(i.circle_color){const e=this.getColumnLabelCircleSpec(t);r.appendChild(V("ellipse",{cx:o,cy:c,rx:e.radius,ry:e.radius,stroke:"rgba(0,0,0,0)",fill:i.circle_color}))}const s=o+(i.left_padding_percent||0)/100*f,d=p(i.angle_in_degrees,at),g=V("text",{x:s,y:c,fill:i.text_color||"#000000","font-size":h,"font-family":"Arial","font-weight":"normal","text-anchor":"start",transform:"rotate("+d+","+s+","+c+")","alignment-baseline":"middle"});g.textContent=i.text,r.appendChild(g)}return r}destroy(){this.$overlay_canvas.off(),c()(document).off("mousemove",this.mouseMoveHandler)}}const ht=25;class ft{constructor(t,e,n){this.$canvas=t,this.model=e,this.tooltip=n,this.supersampling_ratio=2,this.base_font_size=14,this.track_tops={},this.cell_tops={},this.cell_tops_view_space={},this.cell_tops_this_space={},this.cell_heights={},this.cell_heights_view_space={},this.cell_heights_this_space={},this.label_middles_view_space={},this.label_middles_this_space={},this.label_left_padding={},this.labels={},this.sublabels={},this.label_colors={},this.label_circle_colors={},this.label_font_weight={},this.html_labels={},this.track_link_urls={},this.track_descriptions={},this.minimum_track_height=Number.POSITIVE_INFINITY,this.maximum_label_width=Number.NEGATIVE_INFINITY,this.tracks=[],this.rendering_suppressed=!1,this.highlighted_track_label_only=null,this.scroll_y=0;this.show_sublabels=e.getShowTrackSublabels(),this.setUpContext(),function(t){t.drag_callback=function(t,e){},t.dragged_label_track_id=null,t.drag_mouse_y=null,t.$canvas.on("mousedown",(function(n){t.tooltip.hide();const r=t.isMouseOnLabel(n.offsetY);null!==r&&e.getContainingTrackGroup(r).length>1&&!e.isTrackInClusteredGroup(r)&&e.getTrackMovable(r)&&t.startDragging(e,r,n.offsetY)})),t.$canvas.on("mousemove",(function(n){if(null!==t.dragged_label_track_id){const r=e.getContainingTrackGroup(t.dragged_label_track_id),i=e.getLastExpansion(r[r.length-1]),o=t.track_tops[i]+e.getTrackHeight(i)-t.scroll_y,s=t.track_tops[r[0]]-5-t.scroll_y;t.drag_mouse_y=Math.min(n.pageY-t.$canvas.offset().top,o),t.drag_mouse_y=Math.max(t.drag_mouse_y,s),t.renderAllLabels(e)}else{const r=t.isMouseOnLabel(n.pageY-t.$canvas.offset().top);if(null!==r){const n=c()("<div>"),i=t.$canvas[0].getBoundingClientRect();(t.isNecessaryToShortenLabel(t.labels[r])||t.track_link_urls[r])&&n.append(ft.formatTooltipHeader(t.labels[r],t.html_labels[r],t.track_link_urls[r]));const o=t.track_descriptions[r];o.length>0&&n.append(c()("<div>").text(o)),e.getTrackMovable(r)&&(e.isTrackInClusteredGroup(r)?(t.$canvas.css("cursor","not-allowed"),n.append("<b>dragging disabled for clustered tracks</b>")):e.getContainingTrackGroup(r).length>1&&(t.$canvas.css("cursor","move"),n.append("<b>hold to drag</b>"))),n.contents().length>0&&t.tooltip.fadeIn(200,t.renderedLabelWidth(t.labels[r])+i.left,t.cell_tops[r]+i.top-t.scroll_y,n)}else t.$canvas.css("cursor","auto"),t.tooltip.hide()}})),t.$canvas.on("mouseup mouseleave",(function(n){if(null!==t.dragged_label_track_id){const r=e.getContainingTrackGroup(t.dragged_label_track_id),i=t.getLabelAboveMouseSpace(r,n.offsetY,t.dragged_label_track_id);t.stopDragging(e,i)}t.tooltip.hideIfNotAlreadyGoingTo(150)}))}(this)}circleRadius(){return.8*this.minimum_track_height/2}renderedLabelWidth(t){return this.ctx.measureText(this.shortenLabelIfNecessary(t)).width/this.supersampling_ratio}updateFromModel(t){if(!this.rendering_suppressed){this.show_sublabels=t.getShowTrackSublabels(),this.scroll_y=t.getVertScroll(),this.track_tops=t.getZoomedTrackTops(),this.cell_tops=t.getCellTops(),this.cell_tops_this_space={},this.cell_heights={},this.tracks=t.getTracks(),this.track_descriptions={},this.ctx.font="bold "+this.getFontSize()+"px Arial",this.minimum_track_height=Number.POSITIVE_INFINITY,this.maximum_label_width=0;for(let e=0;e<this.tracks.length;e++){this.minimum_track_height=Math.min(this.minimum_track_height,t.getTrackHeight(this.tracks[e]));const n=this.shortenLabelIfNecessary(this.labels[this.tracks[e]]),r=this.shortenLabelIfNecessary(this.sublabels[this.tracks[e]]),i=this.ctx.measureText(n).width+(this.show_sublabels?this.ctx.measureText(r).width:0);this.maximum_label_width=Math.max(this.maximum_label_width,i),this.cell_tops_this_space[this.tracks[e]]=this.cell_tops[this.tracks[e]]*this.supersampling_ratio-this.scroll_y*this.supersampling_ratio,this.track_descriptions[this.tracks[e]]=t.getTrackDescription(this.tracks[e]),this.cell_heights[this.tracks[e]]=t.getCellHeight(this.tracks[e]),this.cell_heights_this_space[this.tracks[e]]=this.cell_heights[this.tracks[e]]*this.supersampling_ratio,this.label_middles_this_space[this.tracks[e]]=this.cell_tops_this_space[this.tracks[e]]+this.cell_heights_this_space[this.tracks[e]]/2}}}setUpContext(){this.ctx=this.$canvas[0].getContext("2d"),this.ctx.textAlign="start",this.ctx.textBaseline="middle"}resizeAndClear(t,e){if(this.rendering_suppressed)return;const n=e(),r=this.getWidth();this.$canvas[0].height=this.supersampling_ratio*n,this.$canvas[0].width=this.supersampling_ratio*r,this.$canvas[0].style.height=n+"px",this.$canvas[0].style.width=r+"px",this.setUpContext()}isNecessaryToShortenLabel(t){return t.length>this.getMaximumLabelLength()}shortenLabelIfNecessary(t){return this.isNecessaryToShortenLabel(t)?t.substring(0,this.getMaximumLabelLength()-3)+"...":t}static formatTooltipHeader(t,e,n){let r;return(r=n?c()('<a target="_blank" rel="noopener noreferrer">').attr("href",n):c()("<span>")).append(e||document.createTextNode(t)),c()('<b style="display: block;">').append(r)}renderAllLabels(t){if(this.rendering_suppressed)return;this.ctx.clearRect(0,0,this.$canvas[0].width,this.$canvas[0].height);const e=[];e.push(...t.getHighlightedTracks()),null!==this.highlighted_track_label_only&&e.push(this.highlighted_track_label_only);for(const t of e)this.cell_tops_this_space.hasOwnProperty(t)&&(this.ctx.fillStyle="rgba(255,255,0,0.4)",this.ctx.fillRect(0,this.cell_tops_this_space[t],this.getWidth()*this.supersampling_ratio,this.cell_heights_this_space[t]));const n=this.getFontSize(),r=this.tracks,i={};for(let t=0;t<r.length;t++){this.label_circle_colors[r[t]]&&(this.ctx.fillStyle=this.label_circle_colors[r[t]],this.ctx.beginPath(),this.ctx.arc(ht*this.supersampling_ratio,this.label_middles_this_space[r[t]],this.supersampling_ratio*this.circleRadius(),0,2*Math.PI),this.ctx.fill()),this.ctx.font=(this.label_font_weight[r[t]]||"bold")+" "+n+"px Arial",this.ctx.fillStyle="black",this.label_colors&&this.label_colors[r[t]]&&(this.ctx.fillStyle=this.label_colors[r[t]]);const e=this.shortenLabelIfNecessary(this.labels[r[t]]);this.ctx.fillText(e,this.label_left_padding[r[t]]*this.supersampling_ratio,this.label_middles_this_space[r[t]]),i[r[t]]=this.ctx.measureText(e).width}if(this.show_sublabels){this.ctx.font=n+"px Arial",this.ctx.fillStyle="rgb(166,166,166)";for(let t=0;t<r.length;t++)this.sublabels[r[t]]&&this.ctx.fillText(this.shortenLabelIfNecessary(this.sublabels[r[t]]),i[r[t]],this.label_middles_this_space[r[t]])}if(null!==this.dragged_label_track_id){this.ctx.font="bold "+n+"px Arial",this.ctx.fillStyle="rgba(255,0,0,0.95)",this.ctx.fillText(this.shortenLabelIfNecessary(this.labels[this.dragged_label_track_id]),0,this.supersampling_ratio*this.drag_mouse_y),this.ctx.fillStyle="rgba(0,0,0,0.15)";const t=this.model.getContainingTrackGroup(this.dragged_label_track_id),e=this.model.getLastExpansion(this.getLabelAboveMouseSpace(t,this.drag_mouse_y,null)),i=this.getLabelBelowMouseSpace(t,this.drag_mouse_y,null);let o,s;if(e===this.dragged_label_track_id||i===this.dragged_label_track_id)return;null!==e&&null!==i?(o=this.cell_tops_this_space[e]+this.cell_heights_this_space[e],s=this.cell_tops_this_space[i]-o):null===e?(o=this.cell_tops_this_space[t[0]]-this.ctx.measureText("m").width,s=this.ctx.measureText("m").width):null===i&&(o=this.cell_tops_this_space[e]+this.cell_heights_this_space[e],s=this.ctx.measureText("m").width);const a=4;s=Math.max(s,a),this.ctx.fillRect(this.label_left_padding[r[r.length-1]]*this.supersampling_ratio,o,this.getWidth()*this.supersampling_ratio,s)}}isMouseOnLabel(t){const e=this.getLabelAboveMouseSpace(this.tracks,t,null);return null===e?null:t<=this.cell_tops[e]-this.scroll_y+this.cell_heights[e]?e:null}getLabelAboveMouseSpace(t,e,n){if(e<this.cell_tops[t[0]]-this.scroll_y)return null;{let r=null;for(let i=0;i<t.length;i++)if(null===n||n!==t[i]){if(this.cell_tops[t[i]]-this.scroll_y>e)break;r=t[i]}return r}}getLabelBelowMouseSpace(t,e,n){if(e>this.cell_tops[t[t.length-1]]-this.scroll_y)return null;{let r=null;for(let i=t.length-1;i>=0;i--)if(null===n||n!==t[i]){if(this.cell_tops[t[i]]-this.scroll_y<e)break;r=t[i]}return r}}startDragging(t,e,n){this.dragged_label_track_id=e,this.drag_mouse_y=n,this.renderAllLabels(t)}stopDragging(t,e){this.drag_callback(this.dragged_label_track_id,e),this.dragged_label_track_id=null,this.renderAllLabels(t)}getMaximumLabelLength(){return 18}getWidth(){return this.model.getShowTrackLabels()?Math.max(this.maximum_label_width/this.supersampling_ratio+10,70):0}getFontSize(t){return(t?1:this.supersampling_ratio)*Math.max(Math.min(this.base_font_size,this.minimum_track_height),7)}setDragCallback(t){this.drag_callback=t}removeTrack(t,e){this.updateFromModel(t),this.resizeAndClear(t,e),this.renderAllLabels(t)}moveTrack(t,e){this.updateFromModel(t),this.resizeAndClear(t,e),this.renderAllLabels(t)}setTrackGroupOrder(t,e){this.updateFromModel(t),this.resizeAndClear(t,e),this.renderAllLabels(t)}setShowTrackLabels(t,e){this.updateFromModel(t),this.resizeAndClear(t,e),this.renderAllLabels(t)}addTracks(t,e,n){for(let n=0;n<e.length;n++)this.labels[e[n]]=t.getTrackLabel(e[n]),this.sublabels[e[n]]=t.getTrackSublabel(e[n]),this.label_colors[e[n]]=t.getTrackLabelColor(e[n]),this.label_circle_colors[e[n]]=t.getTrackLabelCircleColor(e[n]),this.label_left_padding[e[n]]=t.getTrackLabelLeftPadding(e[n]),this.label_font_weight[e[n]]=t.getTrackLabelFontWeight(e[n]),this.html_labels[e[n]]=t.getOptionalHtmlTrackLabel(e[n]),this.track_link_urls[e[n]]=t.getTrackLinkUrl(e[n]);this.updateFromModel(t),this.resizeAndClear(t,n),this.renderAllLabels(t)}setShowTrackSublabels(t,e){this.updateFromModel(t),this.resizeAndClear(t,e),this.renderAllLabels(t)}setScroll(t,e){this.setVertScroll(t,e)}setHorzScroll(t){}setViewport(t,e){this.setVertScroll(t,e)}setVertScroll(t,e){this.updateFromModel(t),this.resizeAndClear(t,e),this.renderAllLabels(t)}setVertZoom(t,e){this.updateFromModel(t),this.resizeAndClear(t,e),this.renderAllLabels(t)}setZoom(t,e){this.setVertZoom(t,e)}highlightTrackLabelOnly(t,e){this.highlighted_track_label_only=t,this.renderAllLabels(e)}setHighlightedTracks(t){this.renderAllLabels(t)}setTrackMovable(t){this.renderAllLabels(t)}setTrackGroupHeader(t,e){this.updateFromModel(t),this.resizeAndClear(t,e),this.renderAllLabels(t)}sort(t,e){this.updateFromModel(t),this.resizeAndClear(t,e),this.renderAllLabels(t)}suppressRendering(){this.rendering_suppressed=!0}releaseRendering(t,e){this.rendering_suppressed=!1,this.updateFromModel(t),this.resizeAndClear(t,e),this.renderAllLabels(t)}toSVGGroup(t,e,n,r){const i=U.group(n||0,r||0);if(!t.getShowTrackLabels())return i;const o=t.getCellTops(),s=t.getTracks();for(let n=0;n<s.length;n++){const r=s[n],a=o[r]+t.getCellHeight(r)/2,l=t.getTrackLabel(r),u=t.getTrackLabelCircleColor(r);u&&i.appendChild(V("ellipse",{cx:ht.toString(),cy:a.toString(),rx:this.circleRadius().toString(),ry:this.circleRadius().toString(),stroke:"rgba(0,0,0,0)",fill:u}));const c=U.text(e?l:this.shortenLabelIfNecessary(l),t.getTrackLabelLeftPadding(r),a,this.getFontSize(!0),"Arial",t.getTrackLabelFontWeight(r)||"bold","bottom",u?"white":"black");c.setAttribute("dy","0.35em"),i.appendChild(c)}return i}}var 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gt(){let t=0;return function(){return t+=1}}function mt(t){t=t||[];const e=["#3366cc","#dc3912","#ff9900","#109618","#990099","#0099c6","#dd4477","#66aa00","#b82e2e","#316395","#994499","#22aa99","#aaaa11","#6633cc","#e67300","#8b0707","#651067","#329262","#5574a6","#3b3eac","#b77322","#16d620","#b91383","#f4359e","#9c5935","#a9c413","#2a778d","#668d1c","#bea413","#0c5922","#743411"];let n=0;const r={};for(let e=0;e<t.length;e++)r[t[e]]=!0;return function(t){if(!t){let t=e[n%e.length];for(;r[t];){const e=yt(t);if(e===t)break;t=e}return r[t]=!0,n+=1,B(t)}r[t]=!0}}function _t(t){return[{type:"rectangle",fill:[255,255,255,1],z:t},{type:"line",stroke:[190,190,190,1],"stroke-width":1,x1:0,x2:100,y1:50,y2:50,z:t}]}!function(t){t.CATEGORICAL="categorical",t.GRADIENT="gradient",t.GRADIENT_AND_CATEGORICAL="gradient+categorical",t.BAR="bar",t.STACKED_BAR="stacked_bar",t.GENE="gene"}(dt||(dt={}));const vt="na",bt="No data";function xt(t){let e=parseInt(t,16);return e*=.95,1===(t=(e=Math.round(e)).toString(16)).length&&(t="0"+t),t}function yt(t){let e=t[1]+t[2],n=t[3]+t[4],r=t[5]+t[6];return"#"+(e=xt(e))+(n=xt(n))+(r=xt(r))}class wt{constructor(t){this.rule_set_id=wt.getRuleSetId(),this.legend_label=t.legend_label,this.legend_base_color=t.legend_base_color,this.exclude_from_legend=t.exclude_from_legend,this.active_rule_ids={},this.rules_with_id=[]}getLegendLabel(){return this.legend_label}getRuleSetId(){return this.rule_set_id}addRules(t){const e=this;return t.map((function(t){return e._addRule(t)}))}_addRule(t,e){return void 0===e&&(e=wt.getRuleId()),this.rules_with_id.push({id:e,rule:new Rt(t)}),e}setUniversalRule(t){this.universal_rule=t}removeRule(t){var e=-1;for(let n=0;n<this.rules_with_id.length;n++)if(this.rules_with_id[n].id===t){e=n;break}e>-1&&this.rules_with_id.splice(e,1),delete this.active_rule_ids[t]}getRuleWithId(t){let e=null;for(let n=0;n<this.rules_with_id.length;n++)if(this.rules_with_id[n].id===t){e=this.rules_with_id[n];break}return e}isExcludedFromLegend(){return this.exclude_from_legend}getRule(t){return this.getRuleWithId(t).rule}getRecentlyUsedRules(){const t=this;return Object.keys(this.active_rule_ids).map((function(e){return t.getRule(parseInt(e,10))}))}applyRulesToDatum(t,e,n,r){let i=[];const o=t.length;for(let s=0;s<o;s++)i=i.concat(t[s].rule.apply(e,n,r));return i}getSpecificRulesForDatum(t){throw"Not implemented on base class"}getUniversalRule(){return this.universal_rule}getUniversalShapes(t,e){if(this.getUniversalRule()){const n=this.getUniversalRule().rule.apply({},t,e);return n.sort(v),n}return[]}getSpecificShapesForDatum(t,e,n,r,i,o){const s=[];for(var a=0;a<t.length;a++){const l=t[a],u=!o||!!o[l[i]],c=this.getSpecificRulesForDatum(l);if(void 0!==r&&u)for(let t=0;t<c.length;t++)r[c[t].id]=!0;const h=this.applyRulesToDatum(c,t[a],e,n);h.sort(v),s.push(h)}return this.getUniversalRule()&&void 0!==r&&(r[this.getUniversalRule().id]=!0),s}}wt.getRuleSetId=gt(),wt.getRuleId=gt();class kt extends wt{constructor(){super(...arguments),this.lookup_map_by_key_and_value={},this.lookup_map_by_key={},this.rule_id_to_conditions={}}getSpecificRulesForDatum(t){if(void 0===t)return this.rules_with_id;let e=[];for(var n in t)if(n in t&&void 0!==t[n]){var r=this.lookup_map_by_key[n];void 0!==r&&e.push(r);var i=this.lookup_map_by_key_and_value[n]&&this.lookup_map_by_key_and_value[n][t[n]]||void 0;void 0!==i&&e.push(i)}return e}indexRuleForLookup(t,e,n){null===t?this.setUniversalRule(n):null===e?this.lookup_map_by_key[t]=n:(this.lookup_map_by_key_and_value[t]=this.lookup_map_by_key_and_value[t]||{},this.lookup_map_by_key_and_value[t][e]=n),this.rule_id_to_conditions[n.id]=this.rule_id_to_conditions[n.id]||[],this.rule_id_to_conditions[n.id].push({key:t,value:e})}addRule(t,e,n){const r=this._addRule(n);return this.indexRuleForLookup(t,e,this.getRuleWithId(r)),r}linkExistingRule(t,e,n){this.indexRuleForLookup(t,e,this.getRuleWithId(n))}removeRule(t){for(super.removeRule(t);this.rule_id_to_conditions[t].length>0;){var e=this.rule_id_to_conditions[t].pop();null===e.key?this.universal_rule=void 0:null===e.value?delete this.lookup_map_by_key[e.key]:delete this.lookup_map_by_key_and_value[e.key][e.value]}delete this.rule_id_to_conditions[t]}}class St extends wt{constructor(t,e){super(t),this.rule_id_to_condition={},e||this.addRule((function(t){return!0===t[vt]}),{shapes:t.na_shapes||_t(t.na_z||1e3),legend_label:t.na_legend_label||bt,exclude_from_legend:!1,legend_config:{type:"rule",target:{na:!0}},legend_order:Number.POSITIVE_INFINITY})}getSpecificRulesForDatum(t){if(void 0===t)return this.rules_with_id;const e=[];for(let n=0;n<this.rules_with_id.length;n++)this.rule_id_to_condition[this.rules_with_id[n].id](t)&&e.push(this.rules_with_id[n]);return e}addRule(t,e,n){return n=this._addRule(e,n),this.rule_id_to_condition[n]=t,n}removeRule(t){super.removeRule(t),delete this.rule_id_to_condition[t]}}class Mt extends kt{constructor(t,e){var n;super(t),e||this.addRule(vt,!0,{shapes:t.na_shapes||_t(t.na_z||1e3),legend_label:t.na_legend_label||bt,exclude_from_legend:!1,legend_config:{type:"rule",target:{na:!0}},legend_order:Number.POSITIVE_INFINITY}),this.category_key=t.category_key,this.universal_rule_categories=t.universal_rule_categories,this.category_to_color=h(p(t.category_to_color,{})),this.getUnusedColor=mt((n=this.category_to_color,Object.keys(n).map((function(t){return n[t]}))).map(G));for(const t of Object.keys(this.category_to_color)){const e=this.category_to_color[t];this.addCategoryRule(t,e),this.getUnusedColor(G(e))}}addCategoryRule(t,e){const n={};n[this.category_key]=t;const r={shapes:[{type:"rectangle",fill:e}],legend_label:t,exclude_from_legend:!1,legend_config:{type:"rule",target:n}};this.universal_rule_categories&&this.universal_rule_categories.hasOwnProperty(t)?this.addRule(null,t,r):this.addRule(this.category_key,t,r)}getSpecificShapesForDatum(t,e,n,r,i,o){for(let e=0,n=t.length;e<n;e++){if(t[e][vt])continue;const n=t[e][this.category_key];if(!(n in this.category_to_color)){const t=this.getUnusedColor();this.category_to_color[n]=t,this.addCategoryRule(n,t)}}return super.getSpecificShapesForDatum(t,e,n,r,i,o)}}var Tt;!function(t){t.ALL="ALL",t.NON_NEGATIVE="NON_NEGATIVE",t.NON_POSITIVE="NON_POSITIVE"}(Tt||(Tt={}));class It extends St{constructor(t){super(t),this.value_key=t.value_key,this.value_range=t.value_range,this.log_scale=t.log_scale,this.type=t.type,this.makeInterpFn=function(){const t=this.getEffectiveValueRange(),e=this.getValueRangeType(),n=this.type;if(this.log_scale){var r=Math.abs(t[0])+1,i=Math.log(t[1]+r)-Math.log(t[0]+r),o=Math.log(t[0]+r);return function(t){return(Math.log(t+r)-o)/i}}return function(r){var i=t[1]-t[0],o=t[0],s=t[1];return"bar"!==n?(r-o)/i:e===Tt.NON_POSITIVE?(r-s)/i:e===Tt.NON_NEGATIVE?(r-o)/i:e===Tt.ALL?r/(i=Math.abs(t[0])>t[1]?Math.abs(t[0]):t[1]):void 0}}}getEffectiveValueRange(){const t=this.value_range&&this.value_range.slice()||[void 0,void 0];return void 0===t[0]&&(t[0]=this.inferred_value_range[0]),void 0===t[1]&&(t[1]=this.inferred_value_range[1]),t[0]===t[1]&&(t[0]-=t[0]/2,t[1]+=t[1]/2),t}getValueRangeType(){var t=this.getEffectiveValueRange();return t[0]<0&&t[1]<=0?Tt.NON_POSITIVE:t[0]>=0&&t[1]>0?Tt.NON_NEGATIVE:Tt.ALL}getSpecificShapesForDatum(t,e,n,r,i,o){let s=Number.POSITIVE_INFINITY,a=Number.NEGATIVE_INFINITY;for(var l=0,u=t.length;l<u;l++){const e=t[l];isNaN(e[this.value_key])||(s=Math.min(s,e[this.value_key]),a=Math.max(a,e[this.value_key]))}return s===Number.POSITIVE_INFINITY&&(s=0),a===Number.NEGATIVE_INFINITY&&(a=0),this.inferred_value_range=[s,a],this.updateLinearRules(),super.getSpecificShapesForDatum(t,e,n,r,i,o)}updateLinearRules(){throw"Not implemented in abstract class"}}class At extends It{constructor(t){super(t),this.colors=[],t.colors?this.colors=t.colors||[]:t.colormap_name&&(this.colors=pt[t.colormap_name]||[]),0===this.colors.length&&this.colors.push([0,0,0,1],[255,0,0,1]),this.value_stop_points=t.value_stop_points,this.null_color=t.null_color||[211,211,211,1];var e=this.value_key;this.addRule((function(t){return!0!==t[vt]&&null===t[e]}),{shapes:[{type:"rectangle",fill:this.null_color}],legend_label:t.null_legend_label||"Not a number",exclude_from_legend:!1,legend_config:{type:"rule",target:{[e]:null}}})}static linInterpColors(t,e,n){return[Math.round(e[0]*(1-t)+n[0]*t),Math.round(e[1]*(1-t)+n[1]*t),Math.round(e[2]*(1-t)+n[2]*t),e[3]*(1-t)+n[3]*t]}makeColorFn(t,e){const n=this.value_stop_points;let r;return r=n?n.map(e):function(t){const e=[];for(let n=0;n<t;n++)e.push(n);return e}(t.length).map((function(e){return e/(t.length-1)})),function(e){var n=i(r,e,(function(t){return t}),!0);if(-1===n)return[0,0,0,1];var o=Math.min(t.length-1,n+1),s=r[o]-r[n];if(0===s)return t[o];var a=(e-r[n])/s,l=t[n],u=t[o];return At.linInterpColors(a,l,u)}}updateLinearRules(){let t;void 0!==this.gradient_rule&&(t=this.gradient_rule,this.removeRule(this.gradient_rule));const e=this.makeInterpFn(),n=this.makeColorFn(this.colors,e),r=this.value_key;this.null_color;this.gradient_rule=this.addRule((function(t){return!0!==t[vt]&&null!==t[r]}),{shapes:[{type:"rectangle",fill:function(t){var i=e(t[r]);return n(i)}}],exclude_from_legend:!1,legend_config:{type:"gradient",range:this.getEffectiveValueRange(),colorFn:n}},t)}}class Ct extends It{constructor(t){super(t),this.fill=t.fill||[0,128,0,1],this.negative_fill=t.negative_fill||[255,0,0,1]}updateLinearRules(){let t;void 0!==this.bar_rule&&(t=this.bar_rule,this.removeRule(this.bar_rule));const e=this.makeInterpFn(),n=this.value_key,r=this.fill,i=this.negative_fill,o=this.getYPosPercentagesFn(),s=this.getCellHeightPercentagesFn();this.bar_rule=this.addRule((function(t){return!0!==t[vt]}),{shapes:[{type:"rectangle",y:function(t){var r=e(t[n]);return o(r)},height:function(t){var r=e(t[n]);return s(r)},fill:function(t){return t[n]<0?i:r}}],exclude_from_legend:!1,legend_config:{type:"number",range:this.getEffectiveValueRange(),range_type:this.getValueRangeType(),positive_color:r,negative_color:i,interpFn:e}},t)}getYPosPercentagesFn(){let t;switch(this.getValueRangeType()){case Tt.NON_POSITIVE:t=function(t){return 0};break;case Tt.NON_NEGATIVE:t=function(t){return 100*(1-t)};break;case Tt.ALL:t=function(t){return 50*Math.min(1-t,1)}}return t}getCellHeightPercentagesFn(){let t;switch(this.getValueRangeType()){case Tt.NON_POSITIVE:t=function(t){return 100*-t};break;case Tt.NON_NEGATIVE:t=function(t){return 100*t};break;case Tt.ALL:t=function(t){return 50*Math.abs(t)}}return t}}class Dt extends St{constructor(t){super(t);const e=t.value_key,n=t.fills||[],r=t.categories||[],i=mt(n.map(G));for(;n.length<r.length;)n.push(i());const o=this;for(let t=0;t<r.length;t++)!function(t){const i={};i[e]={};for(let t=0;t<r.length;t++)i[e][r[t]]=0;i[e][r[t]]=1,o.addRule((function(t){return!0!==t[vt]}),{shapes:[{type:"rectangle",fill:n[t],width:100,height:function(n){for(var i=0,o=0;o<r.length;o++)i+=parseFloat(n[e][r[o]]);return 100*parseFloat(n[e][r[t]])/i},y:function(n){for(var i=0,o=0,s=0;s<r.length;s++){var a=parseFloat(n[e][r[s]]);s<t&&(o+=a),i+=a}return 100*o/i}}],exclude_from_legend:!1,legend_config:{type:"rule",target:i},legend_label:r[t]})}(t)}}class zt extends kt{constructor(t){super(t),this.addRulesFromParams(t),this.addRule(vt,!0,{shapes:t.na_shapes||_t(t.na_z||1),legend_label:t.na_legend_label||bt,exclude_from_legend:!1,legend_config:{type:"rule",target:{na:!0}},legend_order:Number.POSITIVE_INFINITY})}addRulesFromParams(t){const e=t.rule_params;C.a.forEach(e.conditional,(t,e)=>{C.a.forEach(t,(t,n)=>{const r=n.split(","),i={};i[r[0]]=n;const o=this.addRule(e,"*"===r[0]?null:r[0],g(t,{shapes:t.shapes,legend_config:{type:"rule",target:i},legend_base_color:p(this.legend_base_color,[255,255,255,1])}));for(let t=1;t<r.length;t++)this.linkExistingRule(e,"*"===r[t]?null:r[t],o)})}),e.always&&this.addRule(null,null,g(e.always,{shapes:e.always.shapes,legend_config:{type:"rule",target:{}}}))}}class Rt{constructor(t){this.shapes=t.shapes.map((function(t){return"rectangle"===t.type?new rt(t):"triangle"===t.type?new it(t):"ellipse"===t.type?new ot(t):"line"===t.type?new st(t):void 0})),this.legend_label=void 0===t.legend_label?"":t.legend_label,this.legend_base_color=t.legend_base_color,this.exclude_from_legend=t.exclude_from_legend,this.legend_config=t.legend_config,this.legend_order=t.legend_order}getLegendConfig(){return this.legend_config}apply(t,e,n){const r=[];for(let i=0,o=this.shapes.length;i<o;i++)r.push(this.shapes[i].getComputedParams(t,e,n));return r}isExcludedFromLegend(){return this.exclude_from_legend}}class Lt extends wt{constructor(t){super(t),this.gradientRuleSet=new At(t),this.categoricalRuleSet=new Mt(t,!0)}getSpecificShapesForDatum(t,e,n,r,i,o){const s=[];for(let a=0;a<t.length;a++){const l=t[a];this.isCategorical(l)?s.push(this.categoricalRuleSet.getSpecificShapesForDatum([l],e,n,r,i,o)[0]):s.push(this.gradientRuleSet.getSpecificShapesForDatum([l],e,n,r,i,o)[0])}return s}getSpecificRulesForDatum(t){const e=this.categoricalRuleSet.getSpecificRulesForDatum(t),n=this.gradientRuleSet.getSpecificRulesForDatum(t);return e.concat(n)}isCategorical(t){return void 0!==t[this.categoricalRuleSet.category_key]}}var Et=function(t){let e;switch(t.type){case dt.CATEGORICAL:e=new Mt(t);break;case dt.GRADIENT:e=new At(t);break;case dt.GRADIENT_AND_CATEGORICAL:e=new Lt(t);break;case dt.BAR:e=new Ct(t);break;case dt.STACKED_BAR:e=new Dt(t);break;case dt.GENE:default:e=new zt(t)}return e},Ot=n(4),Ft=n.n(Ot);const Nt=20,Pt="oncoprintjs__header__label",Ht="oncoprintjs__header__toggle_btn_img",jt="oncoprintjs__header__open",Vt="oncoprintjs__header__dropdown",$t="oncoprintjs__header__separator",Bt="track-group-",Gt=100,qt=16,Wt="oncoprint-header-view.do-close-menus";class Ut{constructor(t){this.rendering_suppressed=!1,this.$dropdowns=[],t.css({position:"relative","pointer-events":"none"});const e=c()("<div/>").appendTo(t).css({position:"relative","overflow-y":"hidden","overflow-x":"hidden",width:"100%",height:"100%"});this.$occluded_ctr=c()("<div/>").appendTo(e).css({position:"absolute",width:"100%",height:"100%"}),this.$dropdowns_ctr=c()("<div/>").appendTo(t).css({position:"absolute",width:"100%",height:"100%"}),this.clickHandler=()=>{c()(document).trigger(Wt)},c()(document).on("click",this.clickHandler),c()(document).on(Wt,()=>{this.closeAllDropdowns()})}destroy(){c()(document).off("click",this.clickHandler),c()(document).off(Wt)}closeAllDropdowns(){for(const t of this.$dropdowns)t.fadeOut(Gt)}closeDropdownsExcept(t){for(const e of this.$dropdowns)e!==t&&e.fadeOut(Gt);c()(document).trigger(Kt)}static $makeDropdownOption(t,e,n,r){const i=c()("<li>").text(t).css({"font-weight":e,"font-size":12,"border-bottom":"1px solid rgba(0,0,0,0.3)"});return n&&n()?(i.addClass("disabled"),i.css({color:"rgb(200, 200, 200)",cursor:"default"})):r?(i.addClass("clickable"),i.css({cursor:"pointer"}),i.click(r).hover((function(){c()(this).css({"background-color":"rgb(200,200,200)"})}),(function(){c()(this).css({"background-color":"rgba(255,255,255,0)"})}))):i.click((function(t){t.stopPropagation()})),i}static $makeDropdownSeparator(){return c()("<li>").css({"border-top":"1px solid black"}).addClass($t)}render(t){this.$occluded_ctr.empty(),this.$occluded_ctr.css({top:-t.getVertScroll()}),this.$dropdowns_ctr.empty(),this.$dropdowns_ctr.css({top:-t.getVertScroll()}),this.$dropdowns=[];const e=t.getTrackGroups(),n=t.getZoomedHeaderTops();e.forEach((t,e)=>{if(t.header){const r=c()("<div/>").css({"pointer-events":"auto"});if(c()(`<span>${t.header.label.text}</span>`).appendTo(r).css({"margin-right":10,"font-weight":"bold","text-decoration":"underline","font-size":qt,"font-family":"Arial"}).addClass(Pt),t.header.options.length>0){const i=c()("<ul>").appendTo(this.$dropdowns_ctr).css({position:"absolute",width:120,display:"none","list-style-type":"none","padding-left":"6","padding-right":"6",float:"right","background-color":"rgb(255,255,255)",left:"0px",top:n[e]+Nt,"pointer-events":"auto"}).addClass(Vt).addClass(Bt+e);this.$dropdowns.push(i);const o=()=>{i.empty(),t.header.options.forEach(t=>{t.separator?i.append(Ut.$makeDropdownSeparator()):i.append(Ut.$makeDropdownOption(t.label||"",t.weight?t.weight():"normal",t.disabled,(function(n){n.stopPropagation(),t.onClick&&t.onClick(e),o()})))})},s=c()("<img/>").appendTo(r).attr({src:Ft.a,width:Nt,height:Nt}).css({cursor:"pointer",border:"1px solid rgba(125,125,125,0)",display:"inline-block"}).addClass(Ht).addClass(Bt+e).on("click",t=>{t.stopPropagation(),i.is(":visible")?(s.removeClass(jt),i.fadeOut(Gt)):(o(),i.css("left",s.offset().left),s.addClass(jt),i.fadeIn(Gt),this.closeDropdownsExcept(i))})}r.css({position:"absolute",top:n[e],left:0,width:"100%"}),this.$occluded_ctr.append(r)}})}setScroll(t){this.$occluded_ctr.css({top:-t.getVertScroll()}),this.$dropdowns_ctr.css({top:-t.getVertScroll()}),this.closeAllDropdowns()}setVertScroll(t){this.setScroll(t)}suppressRendering(){this.rendering_suppressed=!0}releaseRendering(t){this.rendering_suppressed=!1,this.render(t)}toSVGGroup(t,e,n){const r=U.group(e||0,n||0),i=t.getTrackGroups(),o=t.getZoomedHeaderTops();return i.forEach((t,e)=>{const n=t.header;if(n){const t=o[e];r.appendChild(U.text(n.label.text,0,t,qt,"Arial","bold",void 0,void 0,"underline"))}}),r}}const Zt="oncoprintjs__track_options__toggle_btn_img",Yt="oncoprintjs__track_options__open",Xt="oncoprintjs__track_options__dropdown",Jt="oncoprintjs__track_options__separator",Qt="nth-",Kt="oncoprint-track-options-view.do-close-menus";class te{constructor(t,e,n,r,i,o,s){this.$div=t,this.moveUpCallback=e,this.moveDownCallback=n,this.removeCallback=r,this.sortChangeCallback=i,this.unexpandCallback=o,this.showGapsCallback=s,this.rendering_suppressed=!1,this.track_options_$elts={},this.menu_shown={},this.interaction_disabled=!1;const a=t.css("position");"absolute"!==a&&"relative"!==a&&console.log("WARNING: div passed to OncoprintTrackOptionsView must be absolute or relative positioned - layout problems will occur"),this.$ctr=c()("<div></div>").css({position:"absolute","overflow-y":"hidden","overflow-x":"hidden"}).appendTo(this.$div),this.$buttons_ctr=c()("<div></div>").css({position:"absolute"}).appendTo(this.$ctr),this.$dropdown_ctr=c()("<div></div>").css({position:"absolute"}).appendTo(this.$div);this.clickHandler=function(){c()(document).trigger(Kt)},c()(document).on("click",this.clickHandler)}renderAllOptions(t){if(this.rendering_suppressed)return;const e=this;c()(document).off(Kt),c()(document).on(Kt,(function(){e.hideAllMenus()})),this.$buttons_ctr.empty(),this.$dropdown_ctr.empty(),this.scroll(t.getVertScroll());var n=t.getTracks(),r=Number.POSITIVE_INFINITY;for(let e=0;e<n.length;e++)r=Math.min(r,t.getTrackHeight(n[e]));this.img_size=Math.floor(.75*r);for(let e=0;e<n.length;e++)this.renderTrackOptions(t,n[e],e)}scroll(t){this.rendering_suppressed||(this.$buttons_ctr.css({top:-t}),this.$dropdown_ctr.css({top:-t}),this.hideAllMenus())}resize(t,e){this.rendering_suppressed||(this.$div.css({width:this.getWidth(),height:e()}),this.$ctr.css({width:this.getWidth(),height:e()}))}hideTrackMenu(t){this.menu_shown[t]=!1;const e=this.track_options_$elts[t];e.$dropdown.css({"z-index":1}),e.$dropdown.css({border:"1px solid rgba(125,125,125,0)"}),e.$img.css({border:"1px solid rgba(125,125,125,0)"}),e.$dropdown.fadeOut(100)}showTrackMenu(t){this.menu_shown[t]=!0;const e=this.track_options_$elts[t];e.$dropdown.css({"z-index":10}),e.$dropdown.css({border:"1px solid rgba(125,125,125,1)"}),e.$img.css({border:"1px solid rgba(125,125,125,1)"}),e.$dropdown.fadeIn(100)}hideAllMenus(){for(const t in this.track_options_$elts)this.track_options_$elts.hasOwnProperty(t)&&this.hideTrackMenu(parseInt(t,10))}hideMenusExcept(t){for(const e in this.track_options_$elts)if(this.track_options_$elts.hasOwnProperty(e)){const n=parseInt(e,10);if(n===t)continue;this.hideTrackMenu(n)}c()(document).trigger(Wt)}static $makeDropdownOption(t,e,n,r){const i=c()("<li>").text(t).css({"font-weight":e,"font-size":12,"border-bottom":"1px solid rgba(0,0,0,0.3)"});return n?(i.addClass("disabled"),i.css({color:"rgb(200, 200, 200)",cursor:"default"})):r?(i.addClass("clickable"),i.css({cursor:"pointer"}),i.click(r).hover((function(){c()(this).css({"background-color":"rgb(200,200,200)"})}),(function(){c()(this).css({"background-color":"rgba(255,255,255,0)"})}))):i.click((function(t){t.stopPropagation()})),i}static $makeDropdownSeparator(){return c()("<li>").css({"border-top":"1px solid black"}).addClass(Jt)}static renderSortArrow(t,e,n){let r="";e.isTrackSortDirectionChangeable(n)&&(r={1:'<i class="fa fa-signal" aria-hidden="true" title="Sorted ascending"></i>',"-1":'<i class="fa fa-signal" style="transform: scaleX(-1);" aria-hidden="true" title="Sorted descending"></i>',0:""}[e.getTrackSortDirection(n)]),t.html(r)}renderTrackOptions(t,e,n){let r,i,o,s;const a=t.getZoomedTrackTops(e);r=c()("<div>").appendTo(this.$buttons_ctr).css({position:"absolute",left:"0px",top:a+"px","white-space":"nowrap"}),i=c()("<img/>").appendTo(r).attr({src:Ft.a,width:this.img_size,height:this.img_size}).css({float:"left",cursor:"pointer",border:"1px solid rgba(125,125,125,0)"}).addClass(Zt).addClass(Qt+(n+1)),o=c()("<span>").appendTo(r).css({position:"absolute",top:Math.floor(this.img_size/4)+"px"}),s=c()("<ul>").appendTo(this.$dropdown_ctr).css({position:"absolute",width:120,display:"none","list-style-type":"none","padding-left":"6","padding-right":"6",float:"right","background-color":"rgb(255,255,255)",left:"0px",top:a+this.img_size+"px"}).addClass(Xt).addClass(Qt+(n+1)),this.track_options_$elts[e]={$div:r,$img:i,$dropdown:s},te.renderSortArrow(o,t,e);const l=this;i.hover((function(t){l.menu_shown[e]||c()(this).css({border:"1px solid rgba(125,125,125,0.3)"})}),(function(t){l.menu_shown[e]||c()(this).css({border:"1px solid rgba(125,125,125,0)"})})),i.click((function(t){t.stopPropagation(),s.is(":visible")?(i.addClass(Yt),l.hideTrackMenu(e)):(i.removeClass(Yt),l.showTrackMenu(e)),l.hideMenusExcept(e)}));const u=t.getTrackMovable(e)&&t.isTrackInClusteredGroup(e);if(t.getTrackMovable(e)&&(s.append(te.$makeDropdownOption("Move up","normal",u,(function(t){t.stopPropagation(),l.moveUpCallback(e)}))),s.append(te.$makeDropdownOption("Move down","normal",u,(function(t){t.stopPropagation(),l.moveDownCallback(e)})))),t.isTrackRemovable(e)&&s.append(te.$makeDropdownOption("Remove track","normal",!1,(function(t){t.stopPropagation(),l.removeCallback(e)}))),t.isTrackSortDirectionChangeable(e)){let n,r,i;s.append(te.$makeDropdownSeparator()),n=te.$makeDropdownOption("Sort a-Z",1===t.getTrackSortDirection(e)?"bold":"normal",!1,(function(s){s.stopPropagation(),n.css("font-weight","bold"),r.css("font-weight","normal"),i.css("font-weight","normal"),l.sortChangeCallback(e,1),te.renderSortArrow(o,t,e)})),r=te.$makeDropdownOption("Sort Z-a",-1===t.getTrackSortDirection(e)?"bold":"normal",!1,(function(s){s.stopPropagation(),n.css("font-weight","normal"),r.css("font-weight","bold"),i.css("font-weight","normal"),l.sortChangeCallback(e,-1),te.renderSortArrow(o,t,e)})),i=te.$makeDropdownOption("Don't sort track",0===t.getTrackSortDirection(e)?"bold":"normal",!1,(function(s){s.stopPropagation(),n.css("font-weight","normal"),r.css("font-weight","normal"),i.css("font-weight","bold"),l.sortChangeCallback(e,0),te.renderSortArrow(o,t,e)})),s.append(n),s.append(r),s.append(i)}if(t.isTrackExpandable(e)&&s.append(te.$makeDropdownOption(t.getExpandButtonText(e),"normal",!1,(function(n){n.stopPropagation(),l.renderAllOptions(t),t.expandTrack(e)}))),t.isTrackExpanded(e)&&s.append(te.$makeDropdownOption("Remove expansion","normal",!1,(function(t){t.stopPropagation(),l.unexpandCallback(e)}))),t.getTrackCanShowGaps(e)){s.append(te.$makeDropdownSeparator());const n=te.$makeDropdownOption("Show gaps",t.getTrackShowGaps(e)?"bold":"normal",!1,(function(t){t.stopPropagation(),n.css("font-weight","bold"),r.css("font-weight","normal"),l.showGapsCallback(e,!0)})),r=te.$makeDropdownOption("Don't show gaps",t.getTrackShowGaps(e)?"normal":"bold",!1,(function(t){t.stopPropagation(),n.css("font-weight","normal"),r.css("font-weight","bold"),l.showGapsCallback(e,!1)}));s.append(n),s.append(r)}const h=t.getTrackCustomOptions(e);if(h&&h.length>0)for(var f=0;f<h.length;f++)!function(){var t=h[f];t.separator?s.append(te.$makeDropdownSeparator()):s.append(te.$makeDropdownOption(t.label||"",t.weight||"normal",t.disabled,t.onClick&&function(n){n.stopPropagation(),t.onClick(e)}))}();s.is(":empty")&&(r.remove(),s.remove())}enableInteraction(){this.interaction_disabled=!1}disableInteraction(){this.interaction_disabled=!0}suppressRendering(){this.rendering_suppressed=!0}releaseRendering(t,e){this.rendering_suppressed=!1,this.renderAllOptions(t),this.resize(t,e),this.scroll(t.getVertScroll())}setScroll(t){this.setVertScroll(t)}setHorzScroll(t){}setVertScroll(t){this.scroll(t.getVertScroll())}setZoom(t,e){this.setVertZoom(t,e)}setVertZoom(t,e){this.renderAllOptions(t),this.resize(t,e)}setTrackGroupHeader(t,e){this.renderAllOptions(t),this.resize(t,e)}sort(t,e){this.renderAllOptions(t),this.resize(t,e)}setViewport(t,e){this.renderAllOptions(t),this.resize(t,e),this.scroll(t.getVertScroll())}getWidth(){return this.$buttons_ctr.is(":empty")?0:18+this.img_size}setTrackShowGaps(t,e){this.renderAllOptions(t),this.resize(t,e)}addTracks(t,e){this.renderAllOptions(t),this.resize(t,e)}moveTrack(t,e){this.renderAllOptions(t),this.resize(t,e)}setTrackGroupOrder(t){this.renderAllOptions(t)}setSortConfig(t){this.renderAllOptions(t)}removeTrack(t,e,n){delete this.track_options_$elts[e],this.renderAllOptions(t),this.resize(t,n)}destroy(){c()(document).off("click",this.clickHandler),c()(document).off(Kt)}setTrackCustomOptions(t){this.renderAllOptions(t)}setTrackMovable(t){this.renderAllOptions(t)}}class ee{constructor(t,e,n){this.$div=t,this.base_width=e,this.base_height=n,this.rendering_suppressed=!1,this.rule_set_label_config={weight:"bold",size:12,font:"Arial"},this.rule_label_config={weight:"normal",size:12,font:"Arial"},this.padding_after_rule_set_label=10,this.padding_between_rules=20,this.padding_between_rule_set_rows=10,this.$svg=c()(U.svg(200,200)).appendTo(this.$div),this.width=t.width()}renderLegend(t,e,n){if(this.rendering_suppressed)return;if(void 0===e&&(e=this.$svg[0]),!function(t){let e=!0;for(;t&&"html"!==t.tagName.toLowerCase();){if("none"===c()(t).css("display")){e=!1;break}t=t.parentNode}return e}(e))return;c()(e).empty();const r=U.defs();e.appendChild(r);const i=U.group(0,0);e.appendChild(i);const o=t.getRuleSets();let s=0;for(let a=0;a<o.length;a++){if(o[a].exclude_from_legend&&!n)continue;const l=t.getActiveRules(o[a].rule_set_id);if(0===l.length)continue;const u=U.group(0,s);i.appendChild(u),function(){if(void 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o=this.ruleToSVGGroup(i,t,e,r);o.setAttribute("transform","translate("+c+","+h+")"),u.appendChild(o),c+o.getBBox().width>this.width&&(c=200+this.padding_after_rule_set_label,h=u.getBBox().height+this.padding_between_rule_set_rows,o.setAttribute("transform","translate("+c+","+h+")")),c+=o.getBBox().width,c+=this.padding_between_rules}s+=u.getBBox().height,s+=3*this.padding_between_rule_set_rows}const a=i.getBBox();this.$svg[0].setAttribute("width",a.width.toString()),this.$svg[0].setAttribute("height",(a.height+10).toString())}ruleToSVGGroup(t,e,n,r){const i=U.group(0,0),o=t.getLegendConfig();if("rule"===o.type){const r=t.apply(o.target,e.getCellWidth(!0),this.base_height);if(t.legend_base_color){const n=U.rect(0,0,e.getCellWidth(!0),this.base_height,{type:"rgba",value:t.legend_base_color});i.appendChild(n)}for(let t=0;t<r.length;t++)i.appendChild(U.fromShape(r[t],0,0));if(void 0!==t.legend_label){const r=12,o=U.text(t.legend_label,e.getCellWidth(!0)+5,this.base_height/2,r,"Arial","normal");n.appendChild(o);const s=o.getBBox().height;o.setAttribute("y",(parseFloat(o.getAttribute("y"))-s/2).toString()),n.removeChild(o),i.appendChild(o)}}else if("number"===o.type){const t=2,e=o.range.map((function(e){const n=Math.pow(10,t);return Math.round(e*n)/n}));i.appendChild(U.text(e[0].toString(),0,0,12,"Arial","normal")),i.appendChild(U.text(e[1].toString(),50,0,12,"Arial","normal"));const n=100,s=[];let a=null,l=null;if("NON_POSITIVE"===o.range_type)a=o.negative_color;else if("NON_NEGATIVE"===o.range_type)a=o.positive_color;else if("ALL"===o.range_type){l=U.linearGradient();const t=Math.abs(e[0])/(Math.abs(e[0])+e[1])*100;l.appendChild(U.stop(t,o.negative_color)),l.appendChild(U.stop(t,o.positive_color)),r.appendChild(l)}s.push([5,20]);for(let t=0;t<n;t++){const e=t/n,r=20*o.interpFn((1-e)*o.range[0]+e*o.range[1]);s.push([5+40*t/n,20-r])}s.push([45,20]),i.appendChild(U.path(s,a,a,l))}else 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this.$svg.append(r),this.renderLegend(t,r,!0),r.parentNode.removeChild(r),r}}const ne="oncoprintjs__tooltip";class re{constructor(t,e){this.$container=t,e=e||{},this.$div=c()("<div></div>").addClass(ne).appendTo(t).css({"background-color":"rgba(255,255,255,1)",position:"absolute",display:"none",border:"1px solid black","max-width":300,"min-width":150}),e.noselect&&this.$div.addClass("noselect"),this.hide_timeout_id=void 0,this.show_timeout_id=void 0,this.center=!1,this.shown=!1;const n=this;this.$div.on("mousemove",(function(t){t.stopPropagation(),n.cancelScheduledHide()})),this.$div.on("mouseleave",(function(t){t.stopPropagation(),n.hide()}))}show(t,e,n,r,i){if(this.cancelScheduledHide(),void 0===t||this.shown)this.doShow(e,n,r,i);else{const o=this;this.cancelScheduledShow(),this.show_timeout_id=setTimeout((function(){o.doShow(e,n,r,i)}),t)}}doShow(t,e,n,r){this.cancelScheduledShow(),this.show_timeout_id=void 0,this.$div.empty(),this.$div.css({top:0,left:0,"z-index":9999}),this.$div.append(n),r?this.$div.stop().fadeIn("fast"):this.$div.show();let i=t-(this.center?this.$div.width()/2:0),o=e-this.$div.height();o=Math.max(o,20),o=Math.min(o,c()(window).height()-this.$div.height()),i=Math.max(i,20),i=Math.min(i,c()(window).width()-this.$div.width()-20),this.$div.css({top:o,left:i,"z-index":9999}),this.shown=!0}doHide(t){this.cancelScheduledHide(),this.hide_timeout_id=void 0,t?this.$div.fadeOut():this.$div.hide(),this.shown=!1}cancelScheduledShow(){clearTimeout(this.show_timeout_id),this.show_timeout_id=void 0}cancelScheduledHide(){clearTimeout(this.hide_timeout_id),this.hide_timeout_id=void 0}showIfNotAlreadyGoingTo(t,e,n,r){void 0===this.show_timeout_id&&this.show(t,e,n,r)}hideIfNotAlreadyGoingTo(t){void 0===this.hide_timeout_id&&this.hide(t)}hide(t){if(this.cancelScheduledShow(),this.shown)if(void 0!==t){const e=this;this.cancelScheduledHide(),this.hide_timeout_id=setTimeout((function(){e.doHide()}),t)}else this.doHide()}fadeIn(t,e,n,r){this.show(t,e,n,r,!0)}}class ie{constructor(t,e){this.$div=t,this.tooltip=e,this.base_font_size=12,this.font_family="Arial",this.font_weight="bold",this.width=0,this.$label_elts=[],this.rendering_suppressed=!1,this.tooltip.center=!1,this.$ctr=c()("<div></div>").css({position:"absolute","overflow-y":"hidden","overflow-x":"hidden"}).appendTo(this.$div),this.$text_ctr=c()("<div></div>").css({position:"absolute"}).appendTo(this.$ctr)}destroyLabelElts(){for(let t=0;t<this.$label_elts.length;t++)this.$label_elts[t].off("mousemove mouseleave");this.$label_elts=[]}renderAllInfo(t){if(this.rendering_suppressed)return;this.$text_ctr.empty(),this.destroyLabelElts();const e=t.getTracks();this.minimum_track_height=Number.POSITIVE_INFINITY;for(let n=0;n<e.length;n++)this.minimum_track_height=Math.min(this.minimum_track_height,t.getTrackHeight(e[n]));this.width=0;const n=t.getLabelTops();this.scroll(t.getVertScroll());const r=this.getFontSize(),i=this;for(let o=0;o<e.length;o++)!function(){const s=o,a=c()("<span>").css({position:"absolute","font-family":i.font_family,"font-weight":i.font_weight,"font-size":r}).addClass("noselect"),l=t.getTrackInfo(e[s]);if(!l)return;a.text(l),a.appendTo(i.$text_ctr),i.$label_elts.push(a),setTimeout((function(){a.on("mousemove",(function(){const n=t.$getTrackInfoTooltip(e[s]);if(n){const t=a[0].getBoundingClientRect();i.tooltip.fadeIn(200,t.left,t.top,n)}})).on("mouseleave",(function(){i.tooltip.hideIfNotAlreadyGoingTo(150)}))}),0);const u=n[e[s]]+(t.getCellHeight(e[s])-a.outerHeight())/2;a.css({top:u+"px"}),i.width=Math.max(32,i.width,a[0].clientWidth)}();this.width>0&&(this.width+=10)}scroll(t){this.rendering_suppressed||this.$text_ctr.css({top:-t})}resize(t,e){this.rendering_suppressed||(this.$div.css({width:this.getWidth(),height:e()}),this.$ctr.css({width:this.getWidth(),height:e()}))}getFontSize(){return Math.max(Math.min(this.base_font_size,this.minimum_track_height),7)}getWidth(){return this.width}addTracks(t,e){this.renderAllInfo(t),this.resize(t,e)}moveTrack(t,e){this.renderAllInfo(t),this.resize(t,e)}setTrackGroupOrder(t,e){this.renderAllInfo(t),this.resize(t,e)}removeTrack(t,e){this.renderAllInfo(t),this.resize(t,e)}setTrackInfo(t,e){this.renderAllInfo(t),this.resize(t,e)}setTrackGroupHeader(t,e){this.renderAllInfo(t),this.resize(t,e)}setScroll(t){this.setVertScroll(t)}setHorzScroll(t){}setVertScroll(t){this.scroll(t.getVertScroll())}setZoom(t,e){this.setVertZoom(t,e)}setViewport(t,e){this.renderAllInfo(t),this.resize(t,e),this.scroll(t.getVertScroll())}setVertZoom(t,e){this.renderAllInfo(t),this.resize(t,e)}suppressRendering(){this.rendering_suppressed=!0}releaseRendering(t,e){this.rendering_suppressed=!1,this.renderAllInfo(t),this.resize(t,e),this.scroll(t.getVertScroll())}destroy(){this.destroyLabelElts()}toSVGGroup(t,e,n){const r=U.group(e||0,n||0),i=t.getCellTops(),o=t.getTracks(),s=this.getFontSize();for(let e=0;e<o.length;e++){const n=o[e],a=i[n]+t.getCellHeight(n)/2,l=t.getTrackInfo(n),u=U.text(l,0,a,s,this.font_family,this.font_weight,"bottom");u.setAttribute("dy","0.35em"),r.appendChild(u)}return r}}const oe="v",se="h";class ae{constructor(t,e){this.$div=c()("<div>").css({position:"absolute",top:e.top||0,left:e.left||0}).appendTo(t),(e=e||{}).btn_size=e.btn_size||13,this.onChange=e.onChange||function(){},this.initialize(e),this.value=void 0===e.init_val?.5:e.init_val,this.slider_bar_size=(this.orientation===oe?e.height:e.width)-2*e.btn_size,this.updateSliderPos()}initialize(t){var e=this.$div,n=Math.round(.7*t.btn_size),r=Math.round((t.btn_size-n)/2),i=c()("<div>").css({position:"absolute","background-color":"#ffffff",outline:"solid 1px black"}).appendTo(e),o=c()("<div>").css({position:"absolute","background-color":"#ffffff",border:"solid 1px black","border-radius":"3px",cursor:"pointer"}).appendTo(e),s=c()("<div>").css({position:"absolute","min-height":t.btn_size,"min-width":t.btn_size,"background-color":"#ffffff",border:"solid 1px black","border-radius":"3px",cursor:"pointer"}).appendTo(e);c()("<span>").addClass("icon fa fa-plus").css({position:"absolute",top:r,left:r,"min-width":n,"min-height":n}).appendTo(s);var a=c()("<div>").css({position:"absolute","min-height":t.btn_size,"min-width":t.btn_size,"background-color":"#ffffff",border:"solid 1px black","border-radius":"3px",cursor:"pointer"}).appendTo(e);c()("<span>").addClass("icon fa fa-minus").css({position:"absolute",top:r,left:r,"min-width":n,"min-height":n}).appendTo(a),t.vertical?(i.css({"min-height":t.height-2*t.btn_size,"min-width":Math.round(t.btn_size/5)}),o.css({"min-height":Math.round(t.btn_size/2),"min-width":t.btn_size}),s.css({top:0,left:0}),a.css({top:t.height-t.btn_size,left:0}),i.css({top:t.btn_size,left:.4*t.btn_size}),o.css({left:0}),this.orientation=oe):(i.css({"min-height":Math.round(t.btn_size/5),"min-width":t.width-2*t.btn_size}),o.css({"min-height":t.btn_size,"min-width":Math.round(t.btn_size/2)}),s.css({top:0,left:t.width-t.btn_size}),a.css({top:0,left:0}),i.css({top:.4*t.btn_size,left:t.btn_size}),o.css({top:0}),this.orientation=se);const l=this;s.click((function(){l.value/=.7,t.onChange(l.value)})),a.click((function(){l.value*=.7,t.onChange(l.value)})),[o,s,a].map((function(t){t.hover((function(){c()(this).css({"background-color":"#cccccc"})}),(function(){c()(this).css({"background-color":"#ffffff"})}))})),this.$slider=o,this.$plus_btn=s,this.$minus_btn=a,function(){let t,e,n;function r(n){let r;n.stopPropagation(),n.preventDefault();const i=(r=l.orientation===oe?t-n.pageY:n.pageX-t)/l.slider_bar_size;l.setSliderValue(e+i)}l.$slider.on("mousedown",(function(i){t=l.orientation===oe?i.pageY:i.pageX,e=l.value,n=!0,c()(document).on("mousemove",r)})),c()(document).on("mouseup click",(function(){c()(document).off("mousemove",r),n&&e!==l.value&&l.onChange(l.value),n=!1}))}()}updateSliderPos(){const t=this.value;var e=this.$slider,n=this.getSliderBounds();this.orientation===oe?e.css("top",n.bottom*(1-t)+n.top*t):this.orientation===se&&e.css("left",n.left*(1-t)+n.right*t)}getSliderBounds(){return this.orientation===oe?{bottom:parseInt(this.$minus_btn.css("top"),10)-parseInt(this.$slider.css("min-height"),10),top:parseInt(this.$plus_btn.css("top"),10)+parseInt(this.$plus_btn.css("min-height"),10)}:{left:parseInt(this.$minus_btn.css("left"),10)+parseInt(this.$minus_btn.css("min-width"),10),right:parseInt(this.$plus_btn.css("left"),10)-parseInt(this.$slider.css("min-width"),10)}}setSliderValue(t){var e;this.value=(e=t,Math.max(Math.min(e,1),0)),this.updateSliderPos()}}var le=n(9),ue=n.n(le);class ce{constructor(t,e){this.params=t,this.getCellWidth=e}setParams(t){this.params=t}clone(){return new ce(h(this.params),this.getCellWidth)}get left_col(){return this.params.left_col}get right_col(){return this.params.right_col}get top(){return this.params.top}get height(){return this.params.height}get num_cols(){return this.right_col-this.left_col}get left(){return this.left_col*this.getCellWidth()}get right(){return this.right_col*this.getCellWidth()}get width(){return this.right-this.left}}class he{constructor(t,e,n,r,i,o,s,a,l,u,h,f,d){this.$div=t,this.$canvas=e,this.$overlay_canvas=n,this.layout_numbers={window_width:-1,window_height:-1,vertical_zoom_area_width:-1,horizontal_zoom_area_height:-1,padding:-1,window_bar_height:-1,canvas_left:-1,canvas_top:-1},this.resize_hover=!1,this.rendering_suppressed=!1,this.visible=!1,this.$div=t,this.$canvas=e,this.$overlay_canvas=n,this.current_rect=new ce({top:0,left_col:0,right_col:0,height:0},()=>r.getCellWidth(!0)*this.getZoom(r).x);const p=this;this.handleContextLost=function(){p.drawOncoprintAndOverlayRect(r,i)}.bind(this),this.$canvas[0].addEventListener("webglcontextlost",this.handleContextLost),this.layout_numbers={window_width:4+o+4+20,window_height:24+s+4+20,vertical_zoom_area_width:20,horizontal_zoom_area_height:20,padding:4,window_bar_height:20,canvas_left:4,canvas_top:24},this.$div.css({"min-width":this.layout_numbers.window_width,"min-height":this.layout_numbers.window_height,outline:"solid 1px black","background-color":"#ffffff"}),this.$window_bar=c()("<div>").css({position:"absolute","min-width":this.layout_numbers.window_width,"min-height":this.layout_numbers.window_bar_height,"background-color":"#cccccc"}).appendTo(this.$div),this.$close_btn=c()("<div>").css({position:"absolute",top:3,left:3,"min-width":this.layout_numbers.window_bar_height-6,"min-height":this.layout_numbers.window_bar_height-6,cursor:"pointer"}).appendTo(this.$div),c()("<span>").addClass("icon fa fa-times-circle").css("font-size",this.layout_numbers.window_bar_height-6+"px").appendTo(this.$close_btn),this.$close_btn.click(d||function(){}),this.$canvas[0].width=o,this.$canvas[0].height=s,this.$canvas.css({top:this.layout_numbers.canvas_top,left:this.layout_numbers.canvas_left}),this.$overlay_canvas[0].width=o,this.$overlay_canvas[0].height=o,this.$overlay_canvas.css({top:this.layout_numbers.canvas_top,left:this.layout_numbers.canvas_left,outline:"solid 1px #444444"}),this.horizontal_zoom=new ae(this.$div,{btn_size:this.layout_numbers.horizontal_zoom_area_height-4,horizontal:!0,width:o,init_val:r.getHorzZoom(),left:4,top:this.layout_numbers.canvas_top+s+4,onChange:function(t){u(t)}}),this.vertical_zoom=new ae(this.$div,{btn_size:this.layout_numbers.vertical_zoom_area_width-4,vertical:!0,height:s,init_val:r.getVertZoom(),left:this.layout_numbers.canvas_left+o+4,top:this.layout_numbers.window_bar_height+4,onChange:function(t){h(t)}}),function(){const e=p.layout_numbers.horizontal_zoom_area_height-4,n=p.layout_numbers.vertical_zoom_area_width-4,r=c()("<div>").css({position:"absolute","min-height":e,"min-width":n,outline:"solid 1px black",left:p.layout_numbers.canvas_left+o+4,top:p.layout_numbers.canvas_top+s+4,"background-size":n-4+"px "+(e-4)+"px","background-position":"2px 2px","background-image":"url("+ue.a+")","background-repeat":"no-repeat",cursor:"pointer"}).addClass("oncoprint-zoomtofit-btn").appendTo(t);r.hover((function(){c()(this).css({"background-color":"#cccccc"})}),(function(){c()(this).css({"background-color":"#ffffff"})})),f=f||function(){},r.click(f)}(),this.getWebGLContextAndSetUpMatrices(),this.setUpShaders(),this.overlay_ctx=n[0].getContext("2d");const g=5;function m(t,e){return t>=p.current_rect.left+g&&t<=p.current_rect.left+p.current_rect.width-g&&e>=p.current_rect.top+g&&e<=p.current_rect.top+p.current_rect.height-g}function v(t,e){return t>=p.current_rect.left-g&&t<=p.current_rect.left+p.current_rect.width+g&&e>=p.current_rect.top-g&&e<=p.current_rect.top+p.current_rect.height+g}function b(t,e){return!k(t,e)&&!M(t,e)&&!S(t,e)&&!T(t,e)&&v(t,e)&&Math.abs(t-(p.current_rect.left+p.current_rect.width))<g}function x(t,e){return!k(t,e)&&!M(t,e)&&!S(t,e)&&!T(t,e)&&v(t,e)&&Math.abs(t-p.current_rect.left)<g}function y(t,e){return!k(t,e)&&!M(t,e)&&!S(t,e)&&!T(t,e)&&v(t,e)&&Math.abs(e-p.current_rect.top)<g}function w(t,e){return!k(t,e)&&!M(t,e)&&!S(t,e)&&!T(t,e)&&v(t,e)&&Math.abs(e-(p.current_rect.top+p.current_rect.height))<g}function k(t,e){return Math.abs(e-p.current_rect.top)<g&&Math.abs(t-p.current_rect.left)<g}function S(t,e){return Math.abs(e-(p.current_rect.top+p.current_rect.height))<g&&Math.abs(t-p.current_rect.left)<g}function M(t,e){return Math.abs(e-p.current_rect.top)<g&&Math.abs(t-(p.current_rect.left+p.current_rect.width))<g}function T(t,e){return Math.abs(e-(p.current_rect.top+p.current_rect.height))<g&&Math.abs(t-(p.current_rect.left+p.current_rect.width))<g}function I(t,e){void 0===t?p.resize_hover=!1:b(t,e)?p.resize_hover="r":x(t,e)?p.resize_hover="l":y(t,e)?p.resize_hover="t":w(t,e)?p.resize_hover="b":k(t,e)?p.resize_hover="tl":T(t,e)?p.resize_hover="br":S(t,e)?p.resize_hover="bl":M(t,e)?p.resize_hover="tr":p.resize_hover=!1}function A(e,n){let r;r=void 0===e?"auto":m(e,n)?"move":b(e,n)||x(e,n)?"ew-resize":y(e,n)||w(e,n)?"ns-resize":k(e,n)||T(e,n)?"nwse-resize":S(e,n)||M(e,n)?"nesw-resize":"auto",t.css("cursor",r)}function C(t,e,n){const r=parseInt(t.$canvas[0].style.top,10),i=parseInt(t.$canvas[0].style.left,10),o=parseInt(t.$canvas[0].width,10),s=parseInt(t.$canvas[0].height,10),a=e-i,l=n-r;return{mouse_x:a,mouse_y:l,outside:a<0||a>=o||l<0||l>=s}}let D,z=!1,R=!1,L=-1,E=-1,O=-1,F=-1,N=-1,P=-1;c()(document).on("mousedown",(function(t){const e=p.$div.offset(),n=t.pageX-e.left,i=t.pageY-e.top,o=C(p,n,i);if(!o.outside){const t=o.mouse_x,e=o.mouse_y;z=!1,R=!1,P=r.getOncoprintHeight()/parseInt(p.$canvas[0].height,10),m(t,e)?R="move":b(t,e)?R="resize_r":x(t,e)?R="resize_l":y(t,e)?R="resize_t":w(t,e)?R="resize_b":M(t,e)?R="resize_tr":T(t,e)?R="resize_br":k(t,e)?R="resize_tl":S(t,e)&&(R="resize_bl"),!1!==R&&(z=!0,O=t,F=e,L=r.getClosestColumnIndexToLeft(r.getHorzScroll(),!0),E=r.getVertScroll(),N=r.getVertZoom(),D=p.current_rect.clone())}})),c()(document).on("mousemove",(function(t){const e=p.$div.offset(),n=t.pageX-e.left,o=t.pageY-e.top,s=C(p,n,o),l=s.mouse_x,u=s.mouse_y;let c=p.getZoom(r),h=r.getCellWidth(!0)*c.x;if(z){t.preventDefault();let e=Math.floor(l/h)-Math.floor(O/h),n=u-F;if("move"===R){const t=n*P;a(p.colToLeft(r,_(L+e,0,r.getIdOrder().length-1)),E+t)}else{let t;c=p.getZoom(r);const o=r.getIdOrder().length,s=Math.ceil(i.getVisibleAreaWidth()/(r.getCellWidth(!0)+r.getCellPadding(!0,!0))),a=r.getOncoprintHeight(!0)*c.y,l=i.getVisibleAreaHeight(r)*c.y,u=D.right_col,h=D.top+D.height;"resize_r"===R?(e=_(e,s-D.num_cols,o-D.num_cols),e=Math.min(e,o-u),t={top:D.top,left_col:D.left_col,right_col:D.right_col+e,height:D.height}):"resize_l"===R?(e=_(e,D.num_cols-o,D.num_cols-s),e=Math.max(e,-D.left_col),t={top:D.top,left_col:D.left_col+e,right_col:D.right_col,height:D.height}):"resize_t"===R?(n=_(n,D.height-a,D.height-l),n=Math.max(n,-D.top),t={top:D.top+n,left_col:D.left_col,right_col:D.right_col,height:D.height-n}):"resize_b"===R?(n=_(n,l-D.height,a-D.height),n=Math.min(n,a-h),t={top:D.top,left_col:D.left_col,right_col:D.right_col,height:D.height+n}):"resize_tr"===R?(e=_(e,s-D.num_cols,o-D.num_cols),e=Math.min(e,o-u),n=_(n,D.height-a,D.height-l),n=Math.max(n,-D.top),t={top:D.top+n,left_col:D.left_col,right_col:D.right_col+e,height:D.height-n}):"resize_tl"===R?(e=_(e,D.num_cols-o,D.num_cols-s),e=Math.max(e,-D.left_col),n=_(n,D.height-a,D.height-l),n=Math.max(n,-D.top),t={top:D.top+n,left_col:D.left_col+e,right_col:D.right_col,height:D.height-n}):"resize_br"===R?(n=_(n,l-D.height,a-D.height),n=Math.min(n,a-h),e=_(e,s-D.num_cols,o-D.num_cols),e=Math.min(e,o-u),t={top:D.top,left_col:D.left_col,right_col:D.right_col+e,height:D.height+n}):"resize_bl"===R&&(n=_(n,l-D.height,a-D.height),n=Math.min(n,a-h),e=_(e,D.num_cols-o,D.num_cols-s),e=Math.max(e,-D.left_col),t={top:D.top,left_col:D.left_col+e,right_col:D.right_col,height:D.height+n}),p.current_rect.setParams(t),p.drawOverlayRect(null,null,p.current_rect)}}else s.outside?(A(),I()):(A(l,u),I(l,u)),p.drawOverlayRect(r,i)})),c()(document).on("mouseup",(function(t){const e=p.$div.offset(),n=t.pageX-e.left,o=t.pageY-e.top;z&&(["resize_t","resize_b","resize_l","resize_r","resize_tl","resize_tr","resize_bl","resize_br"].indexOf(R)>-1&&l({left_col:p.current_rect.left_col,scroll_y_proportion:p.current_rect.top/parseInt(p.$canvas[0].height,10),right_col:p.current_rect.right_col,zoom_y:D.height/p.current_rect.height*N}),z=!1,R=!1);const s=C(p,n,o);if(s.outside)A(),I();else{let t=s.mouse_x,e=s.mouse_y;A(t,e),I(t,e)}p.drawOverlayRect(r,i)})),function(){let t=0,e=0,n=0,r=0;function i(i){i.preventDefault();const o=i.pageX-t,s=i.pageY-e;p.setWindowPosition(n+o,r+s)}p.$window_bar.hover((function(){c()(this).css({cursor:"move"})}),(function(){c()(this).css({cursor:"auto"})})),p.$window_bar.on("mousedown",(function(o){t=o.pageX,e=o.pageY,n=parseInt(p.$div.css("left"),10),r=parseInt(p.$div.css("top"),10),c()(document).on("mousemove",i)})),c()(document).on("mouseup click",(function(){c()(document).off("mousemove",i)}))}()}colToLeft(t,e){return t.getZoomedColumnLeft(t.getIdOrder()[e])}get shouldRender(){return this.visible&&!this.rendering_suppressed}getNewCanvas(){const t=this.$canvas[0];t.removeEventListener("webglcontextlost",this.handleContextLost);const e=t.cloneNode();e.addEventListener("webglcontextlost",this.handleContextLost);const n=t.parentNode;n.removeChild(t),n.insertBefore(e,this.$overlay_canvas[0]),this.$canvas=c()(e),this.ctx=null,this.ext=null}getWebGLCanvasContext(){try{const t=this.$canvas[0],e=this.ctx||t.getContext("experimental-webgl",{alpha:!1,antialias:!0});return e.clearColor(1,1,1,1),e.clear(e.COLOR_BUFFER_BIT|e.DEPTH_BUFFER_BIT),e.viewportWidth=t.width,e.viewportHeight=t.height,e.viewport(0,0,e.viewportWidth,e.viewportHeight),e.enable(e.DEPTH_TEST),e.enable(e.BLEND),e.blendEquation(e.FUNC_ADD),e.blendFunc(e.SRC_ALPHA,e.ONE_MINUS_SRC_ALPHA),e.depthMask(!1),e}catch(t){return null}}ensureWebGLContext(){for(let t=0;t<5&&(!this.ctx||this.ctx.isContextLost());t++)this.getNewCanvas(),this.ctx=this.getWebGLCanvasContext(),this.setUpShaders();if(!this.ctx||this.ctx.isContextLost())throw new Error("Unable to get WebGL context for Oncoprint Minimap")}createShaderProgram(t,e){const n=this.ctx.createProgram();if(this.ctx.attachShader(n,t),this.ctx.attachShader(n,e),this.ctx.linkProgram(n),!this.ctx.getProgramParameter(n,this.ctx.LINK_STATUS)){const t=this.ctx.getProgramInfoLog(n);throw this.ctx.deleteProgram(n),"Unable to link shader program: "+t}return n}createShader(t,e){const n=this.ctx.createShader(this.ctx[e]);if(this.ctx.shaderSource(n,t),this.ctx.compileShader(n),!this.ctx.getShaderParameter(n,this.ctx.COMPILE_STATUS)){const t=this.ctx.getShaderInfoLog(n);throw this.ctx.deleteShader(n),"Unable to compile shader: "+t}return n}getWebGLContextAndSetUpMatrices(){this.ctx=this.getWebGLCanvasContext(),this.ctx&&(this.ext=this.ctx.getExtension("ANGLE_instanced_arrays")),function(t){const e=j.a.mat4.create();j.a.mat4.lookAt(e,[0,0,1],[0,0,0],[0,1,0]),t.mvMatrix=e;const n=j.a.mat4.create();j.a.mat4.ortho(n,0,t.ctx.viewportWidth,t.ctx.viewportHeight,0,-5,1e3),t.pMatrix=n}(this)}setUpShaders(){const t=["precision highp float;","attribute float aPosVertex;","attribute float aColVertex;","attribute float aVertexOncoprintColumn;","uniform float columnWidth;","uniform float zoomX;","uniform float zoomY;","uniform mat4 uMVMatrix;","uniform mat4 uPMatrix;","uniform float offsetY;","uniform float positionBitPackBase;","uniform float texSize;","varying float texCoord;","vec3 unpackVec3(float packedVec3, float base) {","\tfloat pos0 = floor(packedVec3 / (base*base));","\tfloat pos0Contr = pos0*base*base;","\tfloat pos1 = floor((packedVec3 - pos0Contr)/base);","\tfloat pos1Contr = pos1*base;","\tfloat pos2 = packedVec3 - pos0Contr - pos1Contr;","\treturn vec3(pos0, pos1, pos2);","}","void main(void) {","\tgl_Position = vec4(unpackVec3(aPosVertex, positionBitPackBase), 1.0);","\tgl_Position[0] += aVertexOncoprintColumn*columnWidth;","\tgl_Position[1] += offsetY;","\tgl_Position *= vec4(zoomX, zoomY, 1.0, 1.0);","\tgl_Position = uPMatrix * uMVMatrix * gl_Position;","\ttexCoord = (aColVertex + 0.5) / texSize;","}"].join("\n"),e=["precision mediump float;","varying float texCoord;","uniform sampler2D uSampler;","void main(void) {","   gl_FragColor = texture2D(uSampler, vec2(texCoord, 0.5));","}"].join("\n"),n=this.createShader(t,"VERTEX_SHADER"),r=this.createShader(e,"FRAGMENT_SHADER"),i=this.createShaderProgram(n,r);i.vertexPositionAttribute=this.ctx.getAttribLocation(i,"aPosVertex"),this.ctx.enableVertexAttribArray(i.vertexPositionAttribute),i.vertexColorAttribute=this.ctx.getAttribLocation(i,"aColVertex"),this.ctx.enableVertexAttribArray(i.vertexColorAttribute),i.vertexOncoprintColumnAttribute=this.ctx.getAttribLocation(i,"aVertexOncoprintColumn"),this.ctx.enableVertexAttribArray(i.vertexOncoprintColumnAttribute),i.samplerUniform=this.ctx.getUniformLocation(i,"uSampler"),i.pMatrixUniform=this.ctx.getUniformLocation(i,"uPMatrix"),i.mvMatrixUniform=this.ctx.getUniformLocation(i,"uMVMatrix"),i.columnWidthUniform=this.ctx.getUniformLocation(i,"columnWidth"),i.zoomXUniform=this.ctx.getUniformLocation(i,"zoomX"),i.zoomYUniform=this.ctx.getUniformLocation(i,"zoomY"),i.offsetYUniform=this.ctx.getUniformLocation(i,"offsetY"),i.positionBitPackBaseUniform=this.ctx.getUniformLocation(i,"positionBitPackBase"),i.texSizeUniform=this.ctx.getUniformLocation(i,"texSize"),this.shader_program=i}getTrackBuffers(t,e){const n=this.ctx.createBuffer(),r=t.vertex_data[e].pos_array,i=t.vertex_data[e].universal_shapes_start_index;this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,n),this.ctx.bufferData(this.ctx.ARRAY_BUFFER,r,this.ctx.STATIC_DRAW),n.itemSize=1,n.specificShapesNumItems=i/n.itemSize,n.universalShapesNumItems=(r.length-i)/n.itemSize;const o=this.ctx.createBuffer(),s=t.vertex_data[e].col_array;this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,o),this.ctx.bufferData(this.ctx.ARRAY_BUFFER,s,this.ctx.STATIC_DRAW),o.itemSize=1,o.specificShapesNumItems=i/o.itemSize,o.universalShapesNumItems=(s.length-i)/o.itemSize;const a=this.ctx.createTexture();this.ctx.bindTexture(this.ctx.TEXTURE_2D,a);const l=t.vertex_data[e].col_bank,u=Math.pow(2,Math.ceil(Math.log2(l.length/4)));for(;l.length<4*u;)l.push(0);this.ctx.texImage2D(this.ctx.TEXTURE_2D,0,this.ctx.RGBA,u,1,0,this.ctx.RGBA,this.ctx.UNSIGNED_BYTE,new Uint8Array(l)),this.ctx.texParameteri(this.ctx.TEXTURE_2D,this.ctx.TEXTURE_MIN_FILTER,this.ctx.NEAREST),this.ctx.texParameteri(this.ctx.TEXTURE_2D,this.ctx.TEXTURE_MAG_FILTER,this.ctx.NEAREST);const c={texture:a,size:u},h=this.ctx.createBuffer(),f=t.vertex_column_array[e];return this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,h),this.ctx.bufferData(this.ctx.ARRAY_BUFFER,new Float32Array(f),this.ctx.STATIC_DRAW),h.itemSize=1,h.numItems=f.length/h.itemSize,{position:n,color:o,color_tex:c,column:h}}getSimpleCountBuffer(t){const e=t.getIdOrder().length,n=this.ctx.createBuffer();return this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,n),this.ctx.bufferData(this.ctx.ARRAY_BUFFER,new Float32Array(C.a.range(0,e)),this.ctx.STATIC_DRAW),n.itemSize=1,n.numItems=e,n}drawOncoprint(t,e){if(!this.shouldRender)return;this.ensureWebGLContext();const n=this.getZoom(t);this.ctx.clearColor(1,1,1,1),this.ctx.clear(this.ctx.COLOR_BUFFER_BIT|this.ctx.DEPTH_BUFFER_BIT);const r=t.getTracks(),i=this.getSimpleCountBuffer(t);for(let o=0;o<r.length;o++){const s=r[o],a=t.getCellTops(s,!0),l=this.getTrackBuffers(e,s);if(0!==l.position.numItems){for(const r of[!1,!0]){const o=this.shader_program;if(this.ctx.useProgram(o),r)this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,l.position),this.ctx.vertexAttribPointer(o.vertexPositionAttribute,l.position.itemSize,this.ctx.FLOAT,!1,0,0),this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,l.color),this.ctx.vertexAttribPointer(o.vertexColorAttribute,l.color.itemSize,this.ctx.FLOAT,!1,0,0),this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,l.column),this.ctx.vertexAttribPointer(o.vertexOncoprintColumnAttribute,l.column.itemSize,this.ctx.FLOAT,!1,0,0),this.ext.vertexAttribDivisorANGLE(o.vertexOncoprintColumnAttribute,0);else{const t=l.position.specificShapesNumItems*l.position.itemSize;this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,l.position),this.ctx.vertexAttribPointer(o.vertexPositionAttribute,l.position.itemSize,this.ctx.FLOAT,!1,0,4*t),this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,l.color),this.ctx.vertexAttribPointer(o.vertexColorAttribute,l.color.itemSize,this.ctx.FLOAT,!1,0,4*t),this.ctx.bindBuffer(this.ctx.ARRAY_BUFFER,i),this.ctx.vertexAttribPointer(o.vertexOncoprintColumnAttribute,1,this.ctx.FLOAT,!1,0,0),this.ext.vertexAttribDivisorANGLE(o.vertexOncoprintColumnAttribute,1)}this.ctx.activeTexture(this.ctx.TEXTURE0),this.ctx.bindTexture(this.ctx.TEXTURE_2D,l.color_tex.texture),this.ctx.uniform1i(this.shader_program.samplerUniform,0),this.ctx.uniform1f(this.shader_program.texSizeUniform,l.color_tex.size),this.ctx.uniformMatrix4fv(this.shader_program.pMatrixUniform,!1,this.pMatrix),this.ctx.uniformMatrix4fv(this.shader_program.mvMatrixUniform,!1,this.mvMatrix),this.ctx.uniform1f(this.shader_program.columnWidthUniform,t.getCellWidth(!0)),this.ctx.uniform1f(this.shader_program.zoomXUniform,n.x),this.ctx.uniform1f(this.shader_program.zoomYUniform,n.y),this.ctx.uniform1f(this.shader_program.offsetYUniform,a),this.ctx.uniform1f(this.shader_program.positionBitPackBaseUniform,e.position_bit_pack_base),r?this.ctx.drawArrays(this.ctx.TRIANGLES,0,l.position.specificShapesNumItems):this.ext.drawArraysInstancedANGLE(this.ctx.TRIANGLES,0,l.position.itemSize*l.position.universalShapesNumItems,i.numItems)}this.ctx.flush()}}}getZoom(t){let e=parseInt(this.$canvas[0].width,10)/t.getOncoprintWidthNoColumnPaddingNoGaps(),n=parseInt(this.$canvas[0].height,10)/t.getOncoprintHeight(!0);return{x:e=Math.max(0,Math.min(1,e)),y:n=Math.max(0,Math.min(1,n))}}drawOverlayRect(t,e,n){if(!this.shouldRender)return;let r,i,o,s,a,l;if(n)r=n.left,i=n.width,o=n.top,s=n.height,a=n.left_col,l=n.right_col;else{const n=t.getCellWidth(!0),u=(t.getCellPadding(!0),e.getViewportOncoprintSpace(t)),c=this.getZoom(t);a=t.getClosestColumnIndexToLeft(u.left,!1),l=t.getClosestColumnIndexToLeft(u.right,!1,!0),r=a*n*c.x,i=(l-a)*n*c.x,o=u.top*c.y,s=(u.bottom-u.top)*c.y}const u=this.overlay_ctx,c=this.$overlay_canvas[0],h=parseInt(c.width,10),f=parseInt(c.height,10);u.fillStyle="rgba(0,0,0,0)",u.clearRect(0,0,h,f),u.fillStyle="rgba(255,255,255,0.4)",u.fillRect(r,o,i,s);const d="t"===this.resize_hover||"tr"===this.resize_hover||"tl"===this.resize_hover,p="r"===this.resize_hover||"tr"===this.resize_hover||"br"===this.resize_hover,g="b"===this.resize_hover||"br"===this.resize_hover||"bl"===this.resize_hover,m="l"===this.resize_hover||"tl"===this.resize_hover||"bl"===this.resize_hover;u.beginPath(),u.moveTo(r,o),u.strokeStyle=d?"rgba(255,0,0,1)":"rgba(0,0,0,0.75)",u.lineWidth=d?2:1,u.lineTo(r+i,o),u.stroke(),u.beginPath(),u.moveTo(r+i,o),u.strokeStyle=p?"rgba(255,0,0,1)":"rgba(0,0,0,0.75)",u.lineWidth=p?2:1,u.lineTo(r+i,o+s),u.stroke(),u.beginPath(),u.moveTo(r+i,o+s),u.strokeStyle=g?"rgba(255,0,0,1)":"rgba(0,0,0,0.75)",u.lineWidth=g?2:1,u.lineTo(r,o+s),u.stroke(),u.beginPath(),u.moveTo(r,o+s),u.strokeStyle=m?"rgba(255,0,0,1)":"rgba(0,0,0,0.75)",u.lineWidth=m?2:1,u.lineTo(r,o),u.stroke(),this.current_rect.setParams({top:o,left_col:a,right_col:l,height:s})}drawOncoprintAndOverlayRect(t,e){this.shouldRender&&(this.drawOncoprint(t,e),this.drawOverlayRect(t,e))}moveTrack(t,e){this.drawOncoprintAndOverlayRect(t,e)}addTracks(t,e){this.drawOncoprintAndOverlayRect(t,e)}removeTrack(t,e){this.drawOncoprintAndOverlayRect(t,e)}setHorzZoom(t,e){this.drawOverlayRect(t,e),this.horizontal_zoom.setSliderValue(t.getHorzZoom())}setVertZoom(t,e){this.drawOverlayRect(t,e),this.vertical_zoom.setSliderValue(t.getVertZoom())}setZoom(t,e){this.drawOverlayRect(t,e),this.horizontal_zoom.setSliderValue(t.getHorzZoom()),this.vertical_zoom.setSliderValue(t.getVertZoom())}setScroll(t,e){this.drawOverlayRect(t,e)}setHorzScroll(t,e){this.drawOverlayRect(t,e)}setVertScroll(t,e){this.drawOverlayRect(t,e)}setViewport(t,e){this.drawOverlayRect(t,e),this.horizontal_zoom.setSliderValue(t.getHorzZoom()),this.vertical_zoom.setSliderValue(t.getVertZoom())}sort(t,e){this.drawOncoprintAndOverlayRect(t,e)}setTrackData(t,e){this.drawOncoprintAndOverlayRect(t,e)}shareRuleSet(t,e){this.drawOncoprintAndOverlayRect(t,e)}setRuleSet(t,e){this.drawOncoprintAndOverlayRect(t,e)}setIdOrder(t,e){this.drawOncoprintAndOverlayRect(t,e)}setTrackGroupHeader(t,e){this.drawOncoprintAndOverlayRect(t,e)}suppressRendering(){this.rendering_suppressed=!0}releaseRendering(t,e){this.rendering_suppressed=!1,this.drawOncoprintAndOverlayRect(t,e)}hideIds(t,e){this.drawOncoprintAndOverlayRect(t,e)}setMinimapVisible(t,e,n){this.visible=t,this.visible&&e&&n&&this.drawOncoprintAndOverlayRect(e,n)}setWindowPosition(t,e){this.$div.css({top:e,left:t})}setWidth(t,e,n){this.$canvas[0].width=t,this.$overlay_canvas[0].width=t,this.getWebGLContextAndSetUpMatrices(),this.setUpShaders(),this.overlay_ctx=this.$overlay_canvas[0].getContext("2d"),this.drawOncoprintAndOverlayRect(e,n)}}n.d(e,"default",(function(){return de})),n.d(e,"RuleSetType",(function(){return dt})),n.d(e,"RuleSet",(function(){return wt})),n.d(e,"LinearInterpRangeType",(function(){return Tt})),n.d(e,"GeneticAlterationRuleSet",(function(){return zt})),n.d(e,"Rule",(function(){return Rt})),n.d(e,"shapeToSvg",(function(){return q}));const fe=function(){let t=0;return function(){return t+=1}}();class de{constructor(t,e,n){this.ctr_selector=t,this.width=e,this.lastSortId=0,this.getCellViewHeight=()=>this.cell_view.getVisibleAreaHeight(this.model),n=n||{};const r=this;if(this.destroyed=!1,this.webgl_unavailable=null===document.createElement("canvas").getContext("experimental-webgl"),this.webgl_unavailable)return void c()(t).append("<p class='oncoprintjs__webgl_unavailable_message'>WebGL context cannot be retrieved, so oncoprint cannot be used. Please visit <a href='http://webglreport.com'>WebGL Report</a> to explore your browsers WebGL capabilities.</p>");const i=c()("<span></span>").css({position:"relative",display:"inline-block"}).appendTo(t),o=c()("<div></div>").css({position:"absolute",display:"inline-block"}).appendTo(i),s=c()("<span></span>").css({position:"fixed",top:0,left:0,"z-index":99999}).appendTo(t),a=c()("<div></div>").css({position:"absolute",display:"inline-block",top:0,left:0,"min-height":1}).appendTo(i),l=c()("<canvas></canvas>").css({display:"inline-block",position:"absolute",left:"0px",top:"0px"}).addClass("noselect").attr({width:"150",height:"250"}),u=c()("<div></div>").css({position:"absolute"}).addClass("oncoprintjs__header_div"),h=c()("<div></div>").css({position:"absolute",left:"150px",top:"0px"}).addClass("noselect").attr({width:"50",height:"250"}),f=c()("<div></div>").css({position:"absolute",top:"250px","min-height":1}).addClass("noselect oncoprint-legend-div"),d=c()("<div>").css({width:e,display:"inline-block",position:"absolute",left:"200px",top:"0px"}).addClass("noselect"),p=c()("<canvas></canvas>").attr({width:"0px",height:"0px"}).css({position:"absolute",top:"0px",left:"0px"}).addClass("noselect"),g=c()("<div>").css({position:"absolute","overflow-x":"scroll","overflow-y":"scroll",top:"0",left:"0px",height:"1px"}).addClass("oncoprintjs__scroll_div"),m=c()("<div>").appendTo(g),v=c()("<canvas></canvas>").attr({width:"0px",height:"0px"}).css({position:"absolute",top:"0px",left:"0px"}).addClass("noselect").addClass("oncoprintjs__cell_overlay_div"),b=c()("<canvas></canvas>").attr({width:"0px",height:"0px"}).css({position:"absolute",top:"0px",left:"0px","pointer-events":"none"}).addClass("noselect").addClass("oncoprintjs__column_label_canvas"),x=c()("<div>").css({position:"absolute"}),y=c()("<div>").css({position:"absolute",outline:"solid 1px black",display:"none"}).addClass("noselect"),w=c()("<canvas></canvas>").attr("width",300).attr("height",300).css({position:"absolute",top:"0px",left:"0px","z-index":0}).addClass("noselect"),k=c()("<canvas></canvas>").attr("width",300).attr("height",300).css({position:"absolute",top:"0px",left:"0px","z-index":1}).addClass("noselect");var S;l.appendTo(o),d.appendTo(o),h.appendTo(o),x.appendTo(o),u.appendTo(o),f.appendTo(a),y.appendTo(i),p.appendTo(d),v.appendTo(d),b.appendTo(d),g.appendTo(d),g.on("mousemove mousedown mouseup",(function(t){v.trigger(t)})),w.appendTo(y),k.appendTo(y),this.$ctr=i,this.$oncoprint_ctr=o,this.$header_div=u,this.$cell_div=d,this.$legend_div=f,this.$track_options_div=h,this.$track_info_div=x,this.$dummy_scroll_div=g,this.$minimap_div=y,this.$cell_canvas=p,this.$cell_overlay_canvas=v,this.model=new P(n),this.header_view=new Ut(this.$header_div),this.cell_view=new ct(d,p,v,b,m,this.model,new re(s),(function(t,e){const n=r.model.getIdsInZoomedLeftInterval(t,e);r.setHorzZoom(r.model.getHorzZoomToFit(r.cell_view.getVisibleAreaWidth(),n)),r.$dummy_scroll_div.scrollLeft(r.model.getZoomedColumnLeft(n[0]))}),(function(t,e){r.doCellMouseOver(t,e)}),(function(t,e){r.doCellClick(t,e)})),this.minimap_view=new he(y,w,k,this.model,this.cell_view,150,150,(function(t,e){r.setScroll(t,e)}),(function(t){r.setViewport(t)}),(function(t){r.setHorzZoomCentered(t)}),(function(t){const e=r.cell_view.getViewportOncoprintSpace(r.model),n=(e.top+e.bottom)/2;r.setVertZoom(t);const i=r.cell_view.getViewportOncoprintSpace(r.model),o=r.model.getVertZoom()*(i.bottom-i.top)/2;r.setVertScroll(n*r.model.getVertZoom()-o)}),(function(){r.updateHorzZoomToFit();const t=r.model.getZoomedColumnLeft();r.setHorzScroll(Math.min.apply(null,r.keep_horz_zoomed_to_fit_ids.map((function(e){return t[e]}))))}),(function(){r.setMinimapVisible(!1)})),this.track_options_view=new te(h,(function(t){const e=r.model.getContainingTrackGroup(t),n=e.indexOf(t);if(n>0){let i=null;n>=2&&(i=e[n-2]),r.moveTrack(t,i)}}),(function(t){const e=r.model.getContainingTrackGroup(t),n=e.indexOf(t);n<e.length-1&&r.moveTrack(t,e[n+1])}),(function(t){const e=r.model.getTrackRemoveOptionCallback(t);e?e(t):r.removeTrack(t)}),(function(t,e){r.setTrackSortDirection(t,e)}),(function(t){r.removeExpansionTracksFor(t)}),r.setTrackShowGaps.bind(r)),this.track_info_view=new ie(x,new re(s)),this.label_view=new ft(l,this.model,new re(s,{noselect:!0})),this.label_view.setDragCallback((function(t,e){r.moveTrack(t,e)})),this.legend_view=new ee(f,10,20),this.keep_horz_zoomed_to_fit=!1,this.keep_horz_zoomed_to_fit_ids=[],this.target_dummy_scroll_left=0,this.target_dummy_scroll_top=0,S=r,g.scroll((function(t){const e=g.scrollLeft(),n=g.scrollTop();if(e!==r.target_dummy_scroll_left||n!==r.target_dummy_scroll_top){r.target_dummy_scroll_left=e,r.target_dummy_scroll_top=n;const t=S.maxDummyScrollDivScroll(),i=t.left,o=t.top;let s=i>0?e/i:0,a=o>0?n/o:0;s=_(s,0,1),a=_(a,0,1);const l=S.maxOncoprintScrollLeft(),u=S.maxOncoprintScrollTop(),c=Math.round(l*s),h=Math.round(u*a);r.keep_horz_zoomed_to_fit=!1,S.doSetScroll(c,h)}})),this.horz_zoom_callbacks=[],this.minimap_close_callbacks=[],this.cell_mouse_over_callbacks=[],this.cell_click_callbacks=[],this.id_clipboard=[],this.clipboard_change_callbacks=[],this.pending_resize_and_organize=!1}incrementLastSortId(){this.lastSortId=(this.lastSortId+1)%1e6}_SetLegendTop(){this.model.rendering_suppressed_depth>0||this.$legend_div.css({top:this.cell_view.getVisibleAreaHeight(this.model)+30})}setLegendTopAfterTimeout(){if(this.model.rendering_suppressed_depth>0)return;const t=this;setTimeout((function(){t.setHeight(),t._SetLegendTop()}),0)}setHeight(){this.$ctr.css({"min-height":this.cell_view.getVisibleAreaHeight(this.model)+Math.max(this.$legend_div.outerHeight(),this.$minimap_div.is(":visible")?this.$minimap_div.outerHeight():0)+30})}resizeAndOrganize(t){if(this.model.rendering_suppressed_depth>0)return;if(0===c()(this.ctr_selector).width())return void(this.pending_resize_and_organize=!0);this.$track_options_div.css({left:this.label_view.getWidth()}),this.$header_div.css({left:0,top:0,width:this.width,height:this.cell_view.getVisibleAreaHeight(this.model)}),this.$track_info_div.css({left:this.label_view.getWidth()+this.track_options_view.getWidth()});const e=this.label_view.getWidth()+this.track_options_view.getWidth()+this.track_info_view.getWidth();this.$cell_div.css("left",e),this.cell_view.setWidth(this.width-e-20,this.model),this._SetLegendTop(),this.legend_view.setWidth(this.width-this.$minimap_div.outerWidth()-20,this.model),this.setHeight(),this.$ctr.css({"min-width":this.width});const n=this;setTimeout((function(){n.keep_horz_zoomed_to_fit&&n.updateHorzZoomToFit(),t&&t()}),0)}resizeAndOrganizeAfterTimeout(t){if(this.model.rendering_suppressed_depth>0)return;const e=this;setTimeout((function(){e.resizeAndOrganize(t)}),0)}maxOncoprintScrollLeft(){return Math.max(0,this.cell_view.getTotalWidth(this.model)-this.cell_view.getVisibleAreaWidth())}maxOncoprintScrollTop(){return Math.max(0,this.cell_view.getTotalHeight(this.model)-this.cell_view.getVisibleAreaHeight(this.model))}maxDummyScrollDivScroll(){const t=this.cell_view.getDummyScrollDivClientSize();return{left:Math.max(0,this.$dummy_scroll_div[0].scrollWidth-t.width),top:Math.max(0,this.$dummy_scroll_div[0].scrollHeight-t.height)}}setMinimapVisible(t){this.webgl_unavailable||this.destroyed||(t?(this.$minimap_div.css({display:"block",top:0,left:c()(this.ctr_selector).width()-this.$minimap_div.outerWidth()-10}),this.minimap_view.setMinimapVisible(!0,this.model,this.cell_view)):(this.$minimap_div.css("display","none"),this.minimap_view.setMinimapVisible(!1),this.executeMinimapCloseCallbacks()),this.resizeAndOrganizeAfterTimeout())}scrollTo(t){this.webgl_unavailable||this.destroyed||this.$dummy_scroll_div.scrollLeft(t)}onHorzZoom(t){this.webgl_unavailable||this.destroyed||this.horz_zoom_callbacks.push(t)}onMinimapClose(t){this.webgl_unavailable||this.destroyed||this.minimap_close_callbacks.push(t)}moveTrack(t,e){this.webgl_unavailable||this.destroyed||(this.model.moveTrack(t,e),this.cell_view.moveTrack(this.model),this.header_view.render(this.model),this.label_view.moveTrack(this.model,this.getCellViewHeight),this.track_options_view.moveTrack(this.model,this.getCellViewHeight),this.track_info_view.moveTrack(this.model,this.getCellViewHeight),this.minimap_view.moveTrack(this.model,this.cell_view),this.model.keep_sorted&&this.model.isSortAffected([t,e],"track")&&this.sort(),this.resizeAndOrganizeAfterTimeout())}setTrackGroupOrder(t,e,n){this.webgl_unavailable||this.destroyed||(this.model.setTrackGroupOrder(t,e),this.cell_view.setTrackGroupOrder(this.model),this.header_view.render(this.model),this.label_view.setTrackGroupOrder(this.model,this.getCellViewHeight),this.track_options_view.setTrackGroupOrder(this.model),this.track_info_view.setTrackGroupOrder(this.model,this.getCellViewHeight),!n&&this.model.keep_sorted&&this.model.isSortAffected(t,"group")&&this.sort(),this.resizeAndOrganizeAfterTimeout())}setTrackGroupLegendOrder(t){this.webgl_unavailable||this.destroyed||(this.model.setTrackGroupLegendOrder(t),this.legend_view.setTrackGroupLegendOrder(this.model),this.resizeAndOrganizeAfterTimeout())}keepSorted(t){if(this.webgl_unavailable||this.destroyed)return;const e=this.model.keep_sorted;this.model.keep_sorted=void 0===t||t,this.model.keep_sorted&&this.model.keep_sorted!==e&&this.sort()}addTracks(t){if(this.webgl_unavailable||this.destroyed)return;const e=[],n=t.map((function(t){return t.track_id=fe(),t.rule_set=Et(t.rule_set_params),e.push(t.track_id),t}));return this.model.addTracks(n),this.cell_view.addTracks(this.model,e),this.label_view.addTracks(this.model,e,this.getCellViewHeight),this.header_view.render(this.model),this.track_options_view.addTracks(this.model,this.getCellViewHeight),this.track_info_view.addTracks(this.model,this.getCellViewHeight),this.legend_view.addTracks(this.model),this.minimap_view.addTracks(this.model,this.cell_view),this.model.keep_sorted&&this.model.isSortAffected(e,"track")&&this.sort(),this.resizeAndOrganizeAfterTimeout(),e}removeTrack(t){this.webgl_unavailable||this.destroyed||(this.model.removeTrack(t),this.cell_view.removeTrack(this.model,t),this.header_view.render(this.model),this.label_view.removeTrack(this.model,this.getCellViewHeight),this.track_options_view.removeTrack(this.model,t,this.getCellViewHeight),this.track_info_view.removeTrack(this.model,this.getCellViewHeight),this.legend_view.removeTrack(this.model),this.minimap_view.removeTrack(this.model,this.cell_view),this.model.keep_sorted&&this.model.isSortAffected(t,"track")&&this.sort(),this.resizeAndOrganizeAfterTimeout())}removeTracks(t){if(!this.webgl_unavailable&&!this.destroyed)for(let e=0;e<t.length;e++)this.removeTrack(t[e])}getTracks(){if(!this.webgl_unavailable&&!this.destroyed)return this.model.getTracks().slice()}removeAllTracks(){if(this.webgl_unavailable||this.destroyed)return;const t=this.model.getTracks();this.removeTracks(t)}removeExpansionTracksFor(t){this.removeTracks(this.model.track_expansion_tracks[t].slice())}disableTrackExpansion(t){this.model.disableTrackExpansion(t)}enableTrackExpansion(t){this.model.enableTrackExpansion(t)}removeAllExpansionTracksInGroup(t){const e=this.model.getTrackGroups()[t].tracks,n=[];let r;for(r=0;r<e.length;r++)this.model.isTrackExpanded(e[r])&&n.push(e[r]);for(this.suppressRendering(),r=0;r<n.length;r++)this.removeExpansionTracksFor(n[r]);this.releaseRendering()}setHorzZoomToFit(t){this.webgl_unavailable||this.destroyed||(this.keep_horz_zoomed_to_fit=!0,this.updateHorzZoomToFitIds(t),this.updateHorzZoomToFit())}updateHorzZoomToFitIds(t){this.webgl_unavailable||this.destroyed||(this.keep_horz_zoomed_to_fit_ids=t.slice(),this.keep_horz_zoomed_to_fit&&this.updateHorzZoomToFit())}updateHorzZoomToFit(){this.setHorzZoom(this.getHorzZoomToFit(this.keep_horz_zoomed_to_fit_ids),!0)}getHorzZoomToFit(t){return t=t||[],this.model.getHorzZoomToFit(this.cell_view.getVisibleAreaWidth(),t)}executeHorzZoomCallbacks(){for(let t=0;t<this.horz_zoom_callbacks.length;t++)this.horz_zoom_callbacks[t](this.model.getHorzZoom())}executeMinimapCloseCallbacks(){for(let t=0;t<this.minimap_close_callbacks.length;t++)this.minimap_close_callbacks[t]()}doCellMouseOver(t,e){null!==t?this.highlightTrackLabelOnly(e):this.highlightTrackLabelOnly(null);for(let n=0;n<this.cell_mouse_over_callbacks.length;n++)this.cell_mouse_over_callbacks[n](t,e)}doCellClick(t,e){for(let n=0;n<this.cell_click_callbacks.length;n++)this.cell_click_callbacks[n](t,e)}getHorzZoom(){if(!this.webgl_unavailable&&!this.destroyed)return this.model.getHorzZoom()}setHorzZoomCentered(t){const e=this.cell_view.getViewportOncoprintSpace(this.model).center_col_index,n=this.model.getIdOrder()[e];this.setHorzZoom(t),this.setHorzScroll(this.model.getZoomedColumnLeft(n)-this.cell_view.visible_area_width/2)}setHorzZoom(t,e){if(!this.webgl_unavailable&&!this.destroyed)return this.keep_horz_zoomed_to_fit=this.keep_horz_zoomed_to_fit&&e,this.model.getHorzZoom()!==t&&(this.model.setHorzZoom(t),this.cell_view.setHorzZoom(this.model),this.minimap_view.setHorzZoom(this.model,this.cell_view),this.executeHorzZoomCallbacks(),this.resizeAndOrganizeAfterTimeout()),this.model.getHorzZoom()}getVertZoom(){if(!this.webgl_unavailable&&!this.destroyed)return this.model.getVertZoom()}setVertZoom(t){if(!this.webgl_unavailable&&!this.destroyed)return this.model.setVertZoom(t),this.cell_view.setVertZoom(this.model),this.header_view.render(this.model),this.label_view.setVertZoom(this.model,this.getCellViewHeight),this.track_info_view.setVertZoom(this.model,this.getCellViewHeight),this.track_options_view.setVertZoom(this.model,this.getCellViewHeight),this.minimap_view.setVertZoom(this.model,this.cell_view),this.resizeAndOrganizeAfterTimeout(),this.model.getVertZoom()}doSetScroll(t,e){t=Math.min(t,this.maxOncoprintScrollLeft()),e=Math.min(e,this.maxOncoprintScrollTop()),this.model.setScroll(t,e),this.cell_view.setScroll(this.model),this.header_view.setScroll(this.model),this.label_view.setScroll(this.model,this.getCellViewHeight),this.track_info_view.setScroll(this.model),this.track_options_view.setScroll(this.model),this.minimap_view.setScroll(this.model,this.cell_view)}setDummyScrollDivScroll(){const t=this.model.getHorzScroll(),e=this.model.getVertScroll(),n=this.maxOncoprintScrollLeft(),r=this.maxOncoprintScrollTop();let i=n>0?t/n:0,o=r>0?e/r:0;i=_(i,0,1),o=_(o,0,1);const s=this.maxDummyScrollDivScroll(),a=s.left,l=s.top;this.target_dummy_scroll_left=Math.round(i*a),this.target_dummy_scroll_top=Math.round(o*l),this.$dummy_scroll_div.scrollLeft(this.target_dummy_scroll_left),this.$dummy_scroll_div.scrollTop(this.target_dummy_scroll_top)}setScroll(t,e){this.webgl_unavailable||this.destroyed||(this.doSetScroll(t,e),this.setDummyScrollDivScroll())}setZoom(t,e){this.webgl_unavailable||this.destroyed||(this.model.setZoom(t,e),this.cell_view.setZoom(this.model),this.header_view.render(this.model),this.label_view.setZoom(this.model,this.getCellViewHeight),this.track_info_view.setZoom(this.model,this.getCellViewHeight),this.track_options_view.setZoom(this.model,this.getCellViewHeight),this.minimap_view.setZoom(this.model,this.cell_view))}setHorzScroll(t){if(!this.webgl_unavailable&&!this.destroyed)return this.model.setHorzScroll(Math.min(t,this.maxOncoprintScrollLeft())),this.cell_view.setHorzScroll(this.model),this.label_view.setHorzScroll(this.model),this.track_info_view.setHorzScroll(this.model),this.track_options_view.setHorzScroll(this.model),this.minimap_view.setHorzScroll(this.model,this.cell_view),this.setDummyScrollDivScroll(),this.model.getHorzScroll()}setVertScroll(t){if(!this.webgl_unavailable&&!this.destroyed)return this.model.setVertScroll(Math.min(t,this.maxOncoprintScrollTop())),this.cell_view.setVertScroll(this.model),this.header_view.setVertScroll(this.model),this.label_view.setVertScroll(this.model,this.getCellViewHeight),this.track_info_view.setVertScroll(this.model),this.track_options_view.setVertScroll(this.model),this.minimap_view.setVertScroll(this.model,this.cell_view),this.setDummyScrollDivScroll(),this.model.getVertScroll()}setViewport(t){if(this.webgl_unavailable||this.destroyed)return;const e=this.model.getHorzZoomToFitCols(this.cell_view.getVisibleAreaWidth(),t.left_col,t.right_col);this.setZoom(e,t.zoom_y);const n=Math.min(this.model.getZoomedColumnLeft(this.model.getIdOrder()[t.left_col]),this.maxOncoprintScrollLeft()),r=Math.min(t.scroll_y_proportion*this.model.getOncoprintHeight(),this.maxOncoprintScrollTop());this.setScroll(n,r),this.executeHorzZoomCallbacks()}getTrackData(t){if(!this.webgl_unavailable&&!this.destroyed)return this.model.getTrackData(t)}getTrackDataIdKey(t){if(!this.webgl_unavailable&&!this.destroyed)return this.model.getTrackDataIdKey(t)}setTrackData(t,e,n){this.webgl_unavailable||this.destroyed||(this.model.setTrackData(t,e,n),this.cell_view.setTrackData(this.model,t),this.header_view.render(this.model),this.legend_view.setTrackData(this.model),this.minimap_view.setTrackData(this.model,this.cell_view),this.model.keep_sorted&&this.model.isSortAffected(t,"track")&&this.sort(),this.resizeAndOrganizeAfterTimeout())}setTrackImportantIds(t,e){this.webgl_unavailable||this.destroyed||(this.model.setTrackImportantIds(t,e),this.cell_view.setTrackImportantIds(this.model,t),this.legend_view.setTrackImportantIds(this.model),this.resizeAndOrganizeAfterTimeout())}setTrackGroupSortPriority(t){this.webgl_unavailable||this.destroyed||(this.model.setTrackGroupSortPriority(t),this.cell_view.setTrackGroupSortPriority(this.model),this.model.keep_sorted&&this.sort(),this.resizeAndOrganizeAfterTimeout())}resetSortableTracksSortDirection(){this.webgl_unavailable||this.destroyed||(this.model.resetSortableTracksSortDirection(!0),this.model.keep_sorted&&this.sort())}setTrackSortDirection(t,e){if(!this.webgl_unavailable&&!this.destroyed)return this.model.isTrackSortDirectionChangeable(t)&&(this.model.setTrackSortDirection(t,e),this.model.keep_sorted&&this.model.isSortAffected(t,"track")&&this.sort(),0===this.model.getTrackSortDirection(t)&&this.model.getTrackShowGaps(t)&&this.setTrackShowGaps(t,!1)),this.model.getTrackSortDirection(t)}setTrackSortComparator(t,e){this.webgl_unavailable||this.destroyed||(this.model.setTrackSortComparator(t,e),this.model.keep_sorted&&this.model.isSortAffected(t,"track")&&this.sort())}getTrackSortDirection(t){if(!this.webgl_unavailable&&!this.destroyed)return this.model.getTrackSortDirection(t)}setTrackInfo(t,e){this.webgl_unavailable||this.destroyed||(this.model.setTrackInfo(t,e),this.track_info_view.setTrackInfo(this.model,this.getCellViewHeight))}setTrackTooltipFn(t,e){this.webgl_unavailable||this.destroyed||this.model.setTrackTooltipFn(t,e)}setShowTrackSublabels(t){this.model.setShowTrackSublabels(t),this.label_view.setShowTrackSublabels(this.model,this.getCellViewHeight),this.resizeAndOrganizeAfterTimeout()}setTrackShowGaps(t,e){this.model.setTrackShowGaps(t,e),0===this.model.getTrackSortDirection(t)&&e&&this.setTrackSortDirection(t,1),this.track_options_view.setTrackShowGaps(this.model,this.getCellViewHeight),this.cell_view.setTrackShowGaps(this.model)}sort(){if(this.webgl_unavailable||this.destroyed)return;const t=this;this.incrementLastSortId();const e=this.lastSortId;this.model.sort().then((function(n){t.lastSortId===e&&(t.label_view.sort(t.model,t.getCellViewHeight),t.track_options_view.sort(t.model,t.getCellViewHeight),t.cell_view.sort(t.model),t.minimap_view.sort(t.model,t.cell_view),n&&t.setTrackGroupOrder(n.track_group_index,n.track_id_order,!0))}))}shareRuleSet(t,e){this.webgl_unavailable||this.destroyed||(this.model.shareRuleSet(t,e),this.cell_view.shareRuleSet(this.model,e),this.legend_view.shareRuleSet(this.model),this.minimap_view.shareRuleSet(this.model,this.cell_view))}setRuleSet(t,e){this.webgl_unavailable||this.destroyed||(this.model.setRuleSet(t,Et(e)),this.cell_view.setRuleSet(this.model,t),this.legend_view.setRuleSet(this.model),this.minimap_view.setRuleSet(this.model,this.cell_view),this.resizeAndOrganizeAfterTimeout())}setSortConfig(t){this.webgl_unavailable||this.destroyed||(this.model.setSortConfig(t),this.cell_view.setSortConfig(this.model),this.track_options_view.setSortConfig(this.model),this.model.keep_sorted&&this.sort())}setIdOrder(t){this.webgl_unavailable||this.destroyed||(this.model.setIdOrder(t),this.cell_view.setIdOrder(this.model,t),this.minimap_view.setIdOrder(this.model,this.cell_view),this.model.keep_sorted&&this.sort())}setTrackGroupHeader(t,e){this.webgl_unavailable||this.destroyed||(this.model.setTrackGroupHeader(t,e),this.label_view.setTrackGroupHeader(this.model,this.getCellViewHeight),this.header_view.render(this.model),this.track_info_view.setTrackGroupHeader(this.model,this.getCellViewHeight),this.track_options_view.setTrackGroupHeader(this.model,this.getCellViewHeight),this.minimap_view.setTrackGroupHeader(this.model,this.cell_view),this.cell_view.setTrackGroupHeader(this.model),this.resizeAndOrganizeAfterTimeout())}disableInteraction(){this.webgl_unavailable||this.destroyed||this.track_options_view.disableInteraction()}enableInteraction(){this.webgl_unavailable||this.destroyed||this.track_options_view.enableInteraction()}suppressRendering(){this.webgl_unavailable||this.destroyed||(this.model.rendering_suppressed_depth+=1,this.label_view.suppressRendering(),this.header_view.suppressRendering(),this.cell_view.suppressRendering(),this.track_options_view.suppressRendering(),this.track_info_view.suppressRendering(),this.legend_view.suppressRendering(),this.minimap_view.suppressRendering())}releaseRendering(t){this.webgl_unavailable||this.destroyed||this.model.rendering_suppressed_depth>0&&(this.model.rendering_suppressed_depth-=1,this.model.rendering_suppressed_depth=Math.max(0,this.model.rendering_suppressed_depth),0===this.model.rendering_suppressed_depth&&(this.model.releaseRendering(),this.label_view.releaseRendering(this.model,this.getCellViewHeight),this.header_view.releaseRendering(this.model),this.cell_view.releaseRendering(this.model),this.track_options_view.releaseRendering(this.model,this.getCellViewHeight),this.track_info_view.releaseRendering(this.model,this.getCellViewHeight),this.legend_view.releaseRendering(this.model),this.minimap_view.releaseRendering(this.model,this.cell_view),this.resizeAndOrganizeAfterTimeout(t)))}triggerPendingResizeAndOrganize(t){this.webgl_unavailable||this.destroyed||this.pending_resize_and_organize&&(this.pending_resize_and_organize=!1,this.resizeAndOrganizeAfterTimeout(t))}hideIds(t,e){this.webgl_unavailable||this.destroyed||(this.model.hideIds(t,e),this.cell_view.hideIds(this.model),this.minimap_view.hideIds(this.model,this.cell_view))}hideTrackLegends(t){this.webgl_unavailable||this.destroyed||(t=[].concat(t),this.model.hideTrackLegends(t),this.legend_view.hideTrackLegends(this.model),this.setLegendTopAfterTimeout())}showTrackLegends(t){this.webgl_unavailable||this.destroyed||(t=[].concat(t),this.model.showTrackLegends(t),this.legend_view.showTrackLegends(this.model),this.setLegendTopAfterTimeout())}setCellPaddingOn(t){this.webgl_unavailable||this.destroyed||(this.model.setCellPaddingOn(t),this.cell_view.setCellPaddingOn(this.model))}setTrackCustomOptions(t,e){this.model.setTrackCustomOptions(t,e),this.track_options_view.setTrackCustomOptions(this.model)}setTrackInfoTooltip(t,e){this.model.setTrackInfoTooltip(t,e)}setTrackMovable(t,e){this.model.setTrackMovable(t,e),this.track_options_view.setTrackMovable(this.model),this.label_view.setTrackMovable(this.model)}setWidth(t){this.width=t,this.resizeAndOrganize()}setColumnLabels(t){this.model.setColumnLabels(t),this.cell_view.setColumnLabels(this.model),this.resizeAndOrganizeAfterTimeout()}setShowTrackLabels(t){this.model.setShowTrackLabels(t),this.label_view.setShowTrackLabels(this.model,this.getCellViewHeight),this.resizeAndOrganizeAfterTimeout()}onCellMouseOver(t){this.cell_mouse_over_callbacks.push(t)}onCellClick(t){this.cell_click_callbacks.push(t)}toSVG(t){if(this.webgl_unavailable||this.destroyed)return;const e=U.svg(10,10);this.$ctr.append(e);const n=U.group(0,0);e.appendChild(n);const r=U.bgrect(10,10,[255,255,255,1]);t&&n.appendChild(r);const i=this.label_view.toSVGGroup(this.model,!0,0,0);n.appendChild(i);const o=this.header_view.toSVGGroup(this.model,0,0);n.appendChild(o);const s=i.getBBox().width,a=s+(s>0?30:0),l=this.track_info_view.toSVGGroup(this.model,a,0);n.appendChild(l);const u=a+l.getBBox().width+10,c=this.cell_view.toSVGGroup(this.model,u,0);n.appendChild(c),n.appendChild(this.legend_view.toSVGGroup(this.model,0,c.getBBox().y+c.getBBox().height+20));const h=n.getBBox(),f=h.x+h.width,d=h.y+h.height;return e.setAttribute("width",f),e.setAttribute("height",d),t&&(r.setAttribute("width",f),r.setAttribute("height",d)),e.parentNode.removeChild(e),e}toCanvas(t,e){if(this.webgl_unavailable||this.destroyed)return;const n=this.toSVG(!0);n.setAttribute("xmlns","http://www.w3.org/2000/svg");const r=parseInt(n.getAttribute("width"),10),i=parseInt(n.getAttribute("height"),10),o=document.createElement("canvas"),s=r*(e=e||1)>8192||i*e>8192;o.setAttribute("width",Math.min(8192,r*e).toString()),o.setAttribute("height",Math.min(8192,i*e).toString());const a=document.createElement("div");a.appendChild(n);const l=a.innerHTML,u="data:image/svg+xml;base64,"+window.btoa(l),c=o.getContext("2d");c.setTransform(e,0,0,e,0,0);const h=new Image;return h.onload=function(){c.drawImage(h,0,0),t(o,s)},h.onerror=function(){console.log("IMAGE LOAD ERROR")},h.src=u,h}toDataUrl(t){this.webgl_unavailable||this.destroyed||this.toCanvas((function(e){t(e.toDataURL())}))}highlightTrackLabelOnly(t){this.webgl_unavailable||this.destroyed||this.label_view.highlightTrackLabelOnly(t,this.model)}setHighlightedTracks(t){this.webgl_unavailable||this.destroyed||(this.model.setHighlightedTracks(t),this.label_view.setHighlightedTracks(this.model),this.cell_view.setHighlightedTracks(this.model))}setHighlightedIds(t){this.webgl_unavailable||this.destroyed||(this.model.setHighlightedIds(t),this.cell_view.setHighlightedIds(this.model))}getIdOrder(t){if(!this.webgl_unavailable&&!this.destroyed)return this.model.getIdOrder(t)}setIdClipboardContents(t){if(!this.webgl_unavailable&&!this.destroyed){this.id_clipboard=t.slice();for(let e=0;e<this.clipboard_change_callbacks.length;e++)this.clipboard_change_callbacks[e](t)}}getIdClipboardContents(){if(!this.webgl_unavailable&&!this.destroyed)return this.id_clipboard.slice()}onClipboardChange(t){this.webgl_unavailable||this.destroyed||this.clipboard_change_callbacks.push(t)}destroy(){this.webgl_unavailable||this.destroyed||(this.cell_view.destroy(),this.header_view.destroy(),this.track_options_view.destroy(),this.track_info_view.destroy(),this.destroyed=!0)}clearMouseOverEffects(){this.webgl_unavailable||this.destroyed||(this.cell_view.clearOverlay(),this.label_view.highlightTrackLabelOnly(null,this.model))}}}]);