mygene-mcp 1.0.0 → 1.0.1

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package/README.md CHANGED
@@ -19,3 +19,22 @@ node dist/index.js
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  ```
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  Data comes from the public Mygene API.
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+
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+ <!-- paywall -->
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+ ## Premium tools
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+
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+ These tools need a license key:
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+
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+ * `gene_pathways`
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+ * `gene_location`
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+
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+ Buy a key at https://mcp-marketplace.io/server/io-github-mrfentmen-mygene-mcp and set it in your MCP client config:
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+
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+ ```json
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+ "env": { "MCP_LICENSE_KEY": "mcp_live_..." }
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+ ```
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+
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+ The key is checked against MCP Marketplace, cached for 24 hours, and keeps
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+ working offline once one check has succeeded. Every other tool on this server
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+ stays free.
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+ <!-- /paywall -->
package/dist/api.js CHANGED
@@ -26,3 +26,59 @@ export async function get(args) {
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  throw new Error(`No gene for id ${args.id}.`);
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  return `Gene ${d.symbol ?? args.id}\n${d.name ?? ''}\nEntrez id: ${d.entrezgene ?? d._id} | taxid ${d.taxid ?? '?'} | ${d.type_of_gene ?? 'gene'}\nSummary: ${(d.summary ?? 'No summary').slice(0, 500)}`;
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  }
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+ async function geneQuery(q, fields, size) {
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+ const res = await fetch(`${BASE}/query?q=${encodeURIComponent(q)}&size=${size}&fields=${fields}`, {
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+ headers: { 'User-Agent': UA, Accept: 'application/json' },
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+ signal: AbortSignal.timeout(25000),
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+ });
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+ if (!res.ok)
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+ throw new Error(`MyGene returned ${res.status}`);
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+ const d = (await res.json());
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+ return d.hits ?? [];
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+ }
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+ export async function genePathways(args) {
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+ const symbol = (args.symbol ?? '').trim();
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+ if (!symbol)
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+ return 'Provide a gene symbol, e.g. TP53.';
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+ const species = (args.species ?? 'human').trim() || 'human';
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+ const limit = Math.max(1, Math.min(args.limit ?? 10, 30));
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+ const hits = await geneQuery(`symbol:${symbol}`, 'symbol,name,taxid,pathway', 1);
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+ const hit = hits[0];
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+ if (!hit)
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+ return `MyGene has no ${species} gene with symbol ${symbol}.`;
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+ const pathway = hit.pathway ?? {};
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+ const lines = [];
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+ for (const [source, entries] of Object.entries(pathway)) {
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+ for (const e of (Array.isArray(entries) ? entries : []).slice(0, limit)) {
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+ lines.push(` ${source}: ${e.name ?? 'not reported'} (${e.id ?? 'no id'})`);
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+ }
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+ }
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+ const head = `Pathways for ${species} gene ${hit.symbol ?? symbol} (${hit.name ?? 'name not reported'}, taxid ${hit.taxid ?? 'not reported'}) - ${lines.length} entries:`;
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+ return lines.length ? `${head}\n${lines.slice(0, limit * 4).join('\n')}` : `MyGene records no pathway annotations for ${species} gene ${symbol}.`;
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+ }
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+ export async function geneLocation(args) {
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+ const id = (args.id ?? '').trim();
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+ if (!id)
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+ return 'Provide a MyGene id, e.g. 7157 or a symbol such as TP53.';
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+ const res = await fetch(`${BASE}/gene/${encodeURIComponent(id)}?fields=symbol,name,taxid,map_location,genomic_pos,type_of_gene,entrezgene,ensembl.gene`, {
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+ headers: { 'User-Agent': UA, Accept: 'application/json' },
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+ signal: AbortSignal.timeout(25000),
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+ });
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+ if (res.status === 404)
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+ return `MyGene has no record for "${id}".`;
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+ if (!res.ok)
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+ throw new Error(`MyGene returned ${res.status}`);
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+ const d = (await res.json());
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+ const say = (v) => (v == null || v === '' ? 'not reported' : String(v));
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+ const pos = d.genomic_pos;
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+ const strand = pos?.strand === 1 ? 'forward' : pos?.strand === -1 ? 'reverse' : 'strand not reported';
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+ return [
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+ `Genome location of ${say(d.symbol)} (${say(d.name)})`,
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+ `MyGene id ${say(d._id)} | taxid ${say(d.taxid)} | type ${say(d.type_of_gene)}`,
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+ `Cytoband: ${say(d.map_location)}`,
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+ `Ensembl gene: ${say(d.ensembl?.gene)} | Entrez gene: ${say(d.entrezgene)}`,
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+ pos
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+ ? `Coordinates: chromosome ${say(pos.chr)}, ${Number(pos.start).toLocaleString()} to ${Number(pos.end).toLocaleString()} (${strand})`
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+ : 'Coordinates: not reported',
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+ ].join('\n');
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+ }
@@ -0,0 +1,79 @@
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+ // Premium tools on this server need a license key bought from MCP Marketplace.
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+ // Buyers put the key in their MCP client config as MCP_LICENSE_KEY. Every tool
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+ // that is not listed in PREMIUM keeps working without a key.
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+ const SLUG = "mygene-mcp";
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+ // Tools that need a key. Everything else is free.
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+ const PREMIUM = new Set([
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+ "gene_pathways",
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+ "gene_location",
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+ ]);
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+ const BUY_URL = `https://mcp-marketplace.io/server/io-github-mrfentmen-${SLUG}`;
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+ // The license check calls the marketplace's verify endpoint directly instead of
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+ // using @mcp_marketplace/license. That SDK sends no `apikey` header, so every
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+ // check it makes is rejected by Supabase before it reaches the function. The
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+ // publishable key below is public by design - it ships in mcp-marketplace.io's
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+ // own JavaScript and only ever reaches their licence check.
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+ const DEFAULT_VERIFY_URL = "https://virupvwhtkpkjsiskckg.supabase.co/functions/v1/verify-key";
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+ const PUBLISHABLE_KEY = "sb_publishable_BuqlW96Ke8C_zzJG-LQv1Q_YHi_r_4h";
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+ const OK_CACHE_MS = 60 * 60 * 1000;
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+ const BAD_CACHE_MS = 60 * 1000;
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+ const seen = new Map();
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+ const REASONS = {
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+ missing_key: "no key is set",
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+ invalid_format: "that key is not a valid MCP Marketplace key",
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+ not_found: "that key was not found",
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+ revoked: "that key has been revoked",
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+ rotated: "that key was rotated, use your new one",
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+ expired: "that key has expired, renew it",
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+ rate_limited: "there were too many checks just now, try again shortly",
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+ network_error: "the license server could not be reached",
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+ };
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+ function blocked(tool, reason) {
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+ const why = REASONS[reason] ?? `the license server answered "${reason}"`;
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+ return `"${tool}" needs a license key, but ${why}. ` +
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+ `Set MCP_LICENSE_KEY in your MCP client config. Get a key: ${BUY_URL}`;
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+ }
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+ async function verify(key) {
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+ const res = await fetch(process.env.MCP_LICENSE_VERIFY_URL || DEFAULT_VERIFY_URL, {
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+ method: "POST",
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+ headers: {
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+ apikey: PUBLISHABLE_KEY,
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+ Authorization: `Bearer ${PUBLISHABLE_KEY}`,
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+ "Content-Type": "application/json",
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+ },
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+ body: JSON.stringify({ key, slug: SLUG }),
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+ // an unusable key answers 400 with a JSON body, so read the body either way
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+ signal: AbortSignal.timeout(15000),
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+ });
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+ const data = (await res.json());
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+ if (typeof data?.valid !== "boolean")
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+ return { valid: false, reason: "unexpected_response" };
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+ return data;
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+ }
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+ /**
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+ * Returns null when the caller may run the tool, or a short message telling
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+ * them how to get a key.
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+ *
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+ * A good key is remembered for an hour, so a busy session does not hit the
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+ * license server on every call and keeps working through a brief outage.
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+ */
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+ export async function premiumRequired(tool) {
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+ if (!PREMIUM.has(tool))
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+ return null;
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+ const key = process.env.MCP_LICENSE_KEY;
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+ if (!key)
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+ return blocked(tool, "missing_key");
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+ const hit = seen.get(key);
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+ if (hit && Date.now() - hit.at < (hit.valid ? OK_CACHE_MS : BAD_CACHE_MS)) {
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+ return hit.valid ? null : blocked(tool, hit.reason ?? "invalid");
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+ }
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+ let result;
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+ try {
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+ result = await verify(key);
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+ }
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+ catch {
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+ result = { valid: false, reason: "network_error" };
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+ }
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+ seen.set(key, { ...result, at: Date.now() });
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+ return result.valid ? null : blocked(tool, result.reason ?? "invalid");
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+ }
package/dist/server.js CHANGED
@@ -1,7 +1,8 @@
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  import { McpServer } from "@modelcontextprotocol/sdk/server/mcp.js";
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  import { z } from "zod";
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  import { get } from "./api.js";
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- import { query } from "./api.js";
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+ import { query, genePathways, geneLocation } from "./api.js";
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+ import { premiumRequired } from "./license.js";
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  const text = (value) => ({ content: [{ type: "text", text: value }] });
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  const textError = (t) => ({ content: [{ type: "text", text: t }], isError: true });
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  const READ_ONLY = { readOnlyHint: true, openWorldHint: true };
@@ -34,5 +35,41 @@ export function createServer() {
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  return textError(error(e));
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  }
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  });
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+ server.registerTool("gene_pathways", {
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+ title: "Gene pathways",
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+ description: "The pathway annotations MyGene holds for a gene: which Biocarta, KEGG, Reactome, WikiPathways and other pathway collections it belongs to.",
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+ inputSchema: z.object({ symbol: z.string().describe("Gene symbol, e.g. TP53."), species: z.string().describe("Species name, e.g. human.").optional(), limit: z.number().int().min(1).max(30).default(10).describe("Max entries per source.") }),
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+ annotations: READ_ONLY,
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+ }, async (args) => {
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+ // ---- paywall: gene_pathways ----
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+ const paywallMessage = await premiumRequired("gene_pathways");
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+ if (paywallMessage)
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+ return { content: [{ type: "text", text: paywallMessage }], isError: true };
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+ // ---- paywall: end ----
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+ try {
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+ return text(await genePathways(args));
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+ }
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+ catch (e) {
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+ return textError(error(e));
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+ }
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+ });
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+ server.registerTool("gene_location", {
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+ title: "Gene location",
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+ description: "Where a gene sits on the genome: cytoband, chromosome, start and end coordinates, strand, plus its Ensembl and Entrez ids.",
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+ inputSchema: z.object({ id: z.string().describe("MyGene id such as 7157, or a symbol such as TP53.") }),
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+ annotations: READ_ONLY,
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+ }, async (args) => {
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+ // ---- paywall: gene_location ----
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+ const paywallMessage = await premiumRequired("gene_location");
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+ if (paywallMessage)
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+ return { content: [{ type: "text", text: paywallMessage }], isError: true };
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+ // ---- paywall: end ----
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+ try {
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+ return text(await geneLocation(args));
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+ }
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+ catch (e) {
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+ return textError(error(e));
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+ }
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+ });
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  return server;
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  }
package/package.json CHANGED
@@ -1,5 +1,5 @@
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  {
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- "version": "1.0.0",
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+ "version": "1.0.1",
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  "type": "module",
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  "repository": {
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  "type": "git",