juice-email-cli 2.4.13 → 2.4.15
This diff represents the content of publicly available package versions that have been released to one of the supported registries. The information contained in this diff is provided for informational purposes only and reflects changes between package versions as they appear in their respective public registries.
- package/edm/elabscience/series/literature/default/juice.yaml +3 -2
- package/edm/elabscience/series/literature/default/snippet.html +3 -1
- package/edm/elabscience/templates/standard/template.html +177 -0
- package/edm/procell/series/literature/default/juice.yaml +3 -2
- package/edm/procell/series/literature/default/snippet.html +3 -1
- package/edm/procell/templates/standard/template.html +8 -0
- package/package.json +1 -1
|
@@ -11,7 +11,7 @@
|
|
|
11
11
|
# ─── 模板变量（Mustache 语法）────────────────────────────────────────────────
|
|
12
12
|
variables:
|
|
13
13
|
overview:
|
|
14
|
-
image: https://elabcomfile.oss-us-west-1.aliyuncs.com/edm/202605211020/
|
|
14
|
+
image: https://elabcomfile.oss-us-west-1.aliyuncs.com/edm/202605211020/overview.webp
|
|
15
15
|
title: "Low-dose oral nicotinamide mononucleotide for immune thrombocytopenia: a phase 1/2 trial"
|
|
16
16
|
link: https://www.nature.com/articles/s41591-026-04366-x
|
|
17
17
|
publicationDate: April 29 2026
|
|
@@ -21,7 +21,8 @@ variables:
|
|
|
21
21
|
keywords: Immune Thrombocytopenia (ITP), Nicotinamide Mononucleotide (NMN), CD38-NAD<sup>+</sup> Axis
|
|
22
22
|
|
|
23
23
|
information:
|
|
24
|
-
image:
|
|
24
|
+
image:
|
|
25
|
+
- https://elabcomfile.oss-us-west-1.aliyuncs.com/edm/202605211020/information.webp
|
|
25
26
|
content: "This study identifies the CD38-NAD<sup>+</sup> axis as an immunometabolic checkpoint in ITP. Anti-CD38 antibodies deplete NAD<sup>+</sup>, driving M1 macrophages and FcγRI upregulation, which increases platelet phagocytosis. Restoring NAD<sup>+</sup> via CD38 inhibition or NMN reprograms macrophages to a resting state and blocks platelet destruction without affecting humoral immunity. In 25 refractory ITP patients, low-dose NMN (450 mg bid × 2 weeks) was well tolerated: 20% achieved platelets ≥50×10<sup>9</sup>/L, and 52% maintained response at week 8, with stable immunoglobulin levels. Thus, targeting CD38-NAD<sup>+</sup> metabolism offers a non-antibody-depleting therapeutic strategy."
|
|
26
27
|
link: https://www.procellsystem.com/resources/publications
|
|
27
28
|
buttonText: View More Publications
|
|
@@ -63,7 +63,9 @@
|
|
|
63
63
|
|
|
64
64
|
<tr>
|
|
65
65
|
<td rowspan="2" style="padding-right: 12px;" class="image-box align-middle">
|
|
66
|
-
|
|
66
|
+
{{#information.image}}
|
|
67
|
+
<img src="{{.}}" />
|
|
68
|
+
{{/information.image}}
|
|
67
69
|
</td>
|
|
68
70
|
<td class="h-0 {{#information.link}}pb-24{{/information.link}}">
|
|
69
71
|
<p>{{information.content}}</p>
|
|
@@ -187,6 +187,18 @@
|
|
|
187
187
|
background-color: #3a82db;
|
|
188
188
|
}
|
|
189
189
|
|
|
190
|
+
.square-icon-title {
|
|
191
|
+
padding-left: 30px;
|
|
192
|
+
color: #006db8;
|
|
193
|
+
font-size: 22px;
|
|
194
|
+
font-weight: bold;
|
|
195
|
+
background: url(https://file.elabscience.com/edm/202606261518/square-blue.webp) 0 8px / 20px 20px no-repeat scroll;
|
|
196
|
+
}
|
|
197
|
+
|
|
198
|
+
.square-icon-title.orange {
|
|
199
|
+
background-image: url(https://file.elabscience.com/edm/202606261518/square-orange.webp);
|
|
200
|
+
}
|
|
201
|
+
|
|
190
202
|
.wifi-title {
|
|
191
203
|
padding-left: 32px;
|
|
192
204
|
color: #2c2c2c;
|
|
@@ -339,10 +351,22 @@
|
|
|
339
351
|
background-color: #006db8;
|
|
340
352
|
}
|
|
341
353
|
|
|
354
|
+
.bg-blue-30 {
|
|
355
|
+
background-color: rgba(0, 109, 184, 0.30);
|
|
356
|
+
}
|
|
357
|
+
|
|
342
358
|
.bg-light-blue {
|
|
343
359
|
background-color: #f9fbfe;
|
|
344
360
|
}
|
|
345
361
|
|
|
362
|
+
.bg-orange {
|
|
363
|
+
background-color: #f7750b;
|
|
364
|
+
}
|
|
365
|
+
|
|
366
|
+
.bg-orange-30 {
|
|
367
|
+
background-color: rgb(247, 117, 11, 0.30);
|
|
368
|
+
}
|
|
369
|
+
|
|
346
370
|
.border {
|
|
347
371
|
border: 1px solid #DCEFF3;
|
|
348
372
|
}
|
|
@@ -367,6 +391,14 @@
|
|
|
367
391
|
position: absolute;
|
|
368
392
|
}
|
|
369
393
|
|
|
394
|
+
.overflow-hidden {
|
|
395
|
+
overflow: hidden;
|
|
396
|
+
}
|
|
397
|
+
|
|
398
|
+
.overflow-auto {
|
|
399
|
+
overflow: auto;
|
|
400
|
+
}
|
|
401
|
+
|
|
370
402
|
.table-auto {
|
|
371
403
|
table-layout: auto;
|
|
372
404
|
}
|
|
@@ -375,6 +407,10 @@
|
|
|
375
407
|
border-collapse: separate;
|
|
376
408
|
}
|
|
377
409
|
|
|
410
|
+
.inline-block {
|
|
411
|
+
display: inline-block;
|
|
412
|
+
}
|
|
413
|
+
|
|
378
414
|
.w-full, .w-100 {
|
|
379
415
|
width: 100%;
|
|
380
416
|
}
|
|
@@ -552,6 +588,10 @@
|
|
|
552
588
|
color: #fff;
|
|
553
589
|
}
|
|
554
590
|
|
|
591
|
+
.color-black {
|
|
592
|
+
color: #000;
|
|
593
|
+
}
|
|
594
|
+
|
|
555
595
|
.color-blue {
|
|
556
596
|
color: #006db8;
|
|
557
597
|
}
|
|
@@ -887,6 +927,143 @@
|
|
|
887
927
|
<td colspan="4" class="h-24"></td>
|
|
888
928
|
</tr>
|
|
889
929
|
|
|
930
|
+
<tr>
|
|
931
|
+
<td></td>
|
|
932
|
+
<td colspan="2">
|
|
933
|
+
<table cellspacing="0" cellpadding="0" border="0">
|
|
934
|
+
<colgroup>
|
|
935
|
+
<col />
|
|
936
|
+
</colgroup>
|
|
937
|
+
|
|
938
|
+
<tbody class="align-middle">
|
|
939
|
+
<tr>
|
|
940
|
+
<td><span class="title color-black">Live‑Cell Imaging, Ultra‑Low Background, True Functional Readout<br />Lysosomal Activity Fluorometric Assay Kit <a href="https://www.elabscience.com/p/lysosomal-activity-fluorometric-assay-kit--e-bc-f202" class="color-blue decoration-none">(E-BC-F202)</a></span></td>
|
|
941
|
+
</tr>
|
|
942
|
+
|
|
943
|
+
<tr>
|
|
944
|
+
<td class="h-16"></td>
|
|
945
|
+
</tr>
|
|
946
|
+
|
|
947
|
+
<tr>
|
|
948
|
+
<td class="pb-8"><span class="square-icon-title">Product Features</span></td>
|
|
949
|
+
</tr>
|
|
950
|
+
|
|
951
|
+
<tr>
|
|
952
|
+
<td>
|
|
953
|
+
<p class="pb-5">• Add dye directly to live cells, image in 1‑6 h, no lysis or sectioning required</p>
|
|
954
|
+
<p class="pb-5">• Self‑quenching probe ensures ultra‑low background and high S/N ratio</p>
|
|
955
|
+
<p class="pb-5">• Detects true proteolytic activity, not pH‑dependent</p>
|
|
956
|
+
<p class="pb-5">• Narrow emission spectrum allows multiplexing with other dyes</p>
|
|
957
|
+
<p>• Excellent photostability and chemical stability for long‑term observation</p>
|
|
958
|
+
</td>
|
|
959
|
+
</tr>
|
|
960
|
+
|
|
961
|
+
<tr>
|
|
962
|
+
<td class="h-16"></td>
|
|
963
|
+
</tr>
|
|
964
|
+
|
|
965
|
+
<tr>
|
|
966
|
+
<td class="pb-8"><span class="square-icon-title">Data Validation</span></td>
|
|
967
|
+
</tr>
|
|
968
|
+
|
|
969
|
+
<tr>
|
|
970
|
+
<td class="text-center overflow-hidden">
|
|
971
|
+
<a href="https://www.elabscience.com/p/lysosomal-activity-fluorometric-assay-kit--e-bc-f202" class="decoration-none image-box inline-block bg-blue-30 relative" style="padding: 5px 8px;">
|
|
972
|
+
<img src="https://file.elabscience.com/edm/202606261518/E-BC-F202.webp" />
|
|
973
|
+
<img src="https://file.elabscience.com/edm/202606261518/finger-point.webp" class="absolute" style="right: 24px; bottom: 18px; transform: translateX(100%);" />
|
|
974
|
+
</a>
|
|
975
|
+
</td>
|
|
976
|
+
</tr>
|
|
977
|
+
|
|
978
|
+
<tr>
|
|
979
|
+
<td class="pt-8">Figure 1. Bafilomycin A1‑treated cells show markedly reduced red fluorescence, indicating decreased lysosomal activity.</td>
|
|
980
|
+
</tr>
|
|
981
|
+
|
|
982
|
+
<tr>
|
|
983
|
+
<td class="h-16"></td>
|
|
984
|
+
</tr>
|
|
985
|
+
|
|
986
|
+
<tr>
|
|
987
|
+
<td class="text-center"><a href="https://www.elabscience.com/p/lysosomal-activity-fluorometric-assay-kit--e-bc-f202" class="button font-bold decoration-none">Get More Details</a></td>
|
|
988
|
+
</tr>
|
|
989
|
+
</tbody>
|
|
990
|
+
</table>
|
|
991
|
+
</td>
|
|
992
|
+
<td></td>
|
|
993
|
+
</tr>
|
|
994
|
+
|
|
995
|
+
<tr>
|
|
996
|
+
<td colspan="4" class="h-24"></td>
|
|
997
|
+
</tr>
|
|
998
|
+
|
|
999
|
+
<tr>
|
|
1000
|
+
<td></td>
|
|
1001
|
+
<td colspan="2">
|
|
1002
|
+
<table cellspacing="0" cellpadding="0" border="0">
|
|
1003
|
+
<colgroup>
|
|
1004
|
+
<col />
|
|
1005
|
+
</colgroup>
|
|
1006
|
+
|
|
1007
|
+
<tbody class="align-middle">
|
|
1008
|
+
<tr>
|
|
1009
|
+
<td><span class="title color-black">High‑Specificity, Real‑Time Quantification<br />Singlet Oxygen(<sup>1</sup>O<sub>2</sub>) Fluorometric Assay Kit <a href="https://www.elabscience.com/p/singlet-oxygen-1o2-fluorometric-assay-kit--e-bc-f062" class="color-blue decoration-none">(E-BC-F062)</a></span></td>
|
|
1010
|
+
</tr>
|
|
1011
|
+
|
|
1012
|
+
<tr>
|
|
1013
|
+
<td class="h-16"></td>
|
|
1014
|
+
</tr>
|
|
1015
|
+
|
|
1016
|
+
<tr>
|
|
1017
|
+
<td class="pb-8"><span class="square-icon-title orange">Product Features</span></td>
|
|
1018
|
+
</tr>
|
|
1019
|
+
|
|
1020
|
+
<tr>
|
|
1021
|
+
<td>
|
|
1022
|
+
<p class="pb-5">• High specificity for <sup>1</sup>O<sub>2</sub>, minimal interference from other ROS</p>
|
|
1023
|
+
<p class="pb-5">• Real‑time quantitative detection in live cells</p>
|
|
1024
|
+
<p class="pb-5">• Compatible with flow cytometry and fluorescence microscopy</p>
|
|
1025
|
+
<p>• Simple protocol with reliable and reproducible results</p>
|
|
1026
|
+
</td>
|
|
1027
|
+
</tr>
|
|
1028
|
+
|
|
1029
|
+
<tr>
|
|
1030
|
+
<td class="h-16"></td>
|
|
1031
|
+
</tr>
|
|
1032
|
+
|
|
1033
|
+
<tr>
|
|
1034
|
+
<td class="pb-8"><span class="square-icon-title orange">Data Validation</span></td>
|
|
1035
|
+
</tr>
|
|
1036
|
+
|
|
1037
|
+
<tr>
|
|
1038
|
+
<td class="text-center overflow-hidden">
|
|
1039
|
+
<a href="https://www.elabscience.com/p/singlet-oxygen-1o2-fluorometric-assay-kit--e-bc-f062" class="decoration-none image-box inline-block bg-orange-30 relative" style="padding: 5px 8px;">
|
|
1040
|
+
<img src="https://file.elabscience.com/edm/202606261518/E-BC-F062.webp" />
|
|
1041
|
+
<img src="https://file.elabscience.com/edm/202606261518/finger-point.webp" class="absolute" style="right: 24px; bottom: 18px; transform: translateX(100%);" />
|
|
1042
|
+
</a>
|
|
1043
|
+
</td>
|
|
1044
|
+
</tr>
|
|
1045
|
+
|
|
1046
|
+
<tr>
|
|
1047
|
+
<td class="pt-8">Figure 2. H<sub>2</sub>O<sub>2</sub>‑stimulated cells exhibit significantly increased green fluorescence, indicating elevated <sup>1</sup>O<sub>2</sub> levels.</td>
|
|
1048
|
+
</tr>
|
|
1049
|
+
|
|
1050
|
+
<tr>
|
|
1051
|
+
<td class="h-16"></td>
|
|
1052
|
+
</tr>
|
|
1053
|
+
|
|
1054
|
+
<tr>
|
|
1055
|
+
<td class="text-center"><a href="https://www.elabscience.com/p/singlet-oxygen-1o2-fluorometric-assay-kit--e-bc-f062" class="button font-bold decoration-none bg-orange">Get More Details</a></td>
|
|
1056
|
+
</tr>
|
|
1057
|
+
</tbody>
|
|
1058
|
+
</table>
|
|
1059
|
+
</td>
|
|
1060
|
+
<td></td>
|
|
1061
|
+
</tr>
|
|
1062
|
+
|
|
1063
|
+
<tr>
|
|
1064
|
+
<td colspan="4" class="h-24"></td>
|
|
1065
|
+
</tr>
|
|
1066
|
+
|
|
890
1067
|
<tr>
|
|
891
1068
|
<td></td>
|
|
892
1069
|
<td colspan="2" class="bg-gray" style="padding: 0 16px 16px;">
|
|
@@ -11,7 +11,7 @@
|
|
|
11
11
|
# ─── 模板变量（Mustache 语法）────────────────────────────────────────────────
|
|
12
12
|
variables:
|
|
13
13
|
overview:
|
|
14
|
-
image: https://pri-cella.oss-ap-southeast-1.aliyuncs.com/edm/202604211419/
|
|
14
|
+
image: https://pri-cella.oss-ap-southeast-1.aliyuncs.com/edm/202604211419/overview.webp
|
|
15
15
|
title: "Low-dose oral nicotinamide mononucleotide for immune thrombocytopenia: a phase 1/2 trial"
|
|
16
16
|
link: https://www.nature.com/articles/s41467-026-70340-3
|
|
17
17
|
publicationDate: April 29 2026
|
|
@@ -21,7 +21,8 @@ variables:
|
|
|
21
21
|
keywords: Immune Thrombocytopenia (ITP), Nicotinamide Mononucleotide (NMN), CD38-NAD<sup>+</sup> Axis
|
|
22
22
|
|
|
23
23
|
information:
|
|
24
|
-
image:
|
|
24
|
+
image:
|
|
25
|
+
- https://pri-cella.oss-ap-southeast-1.aliyuncs.com/edm/202604211419/information.webp
|
|
25
26
|
content: "This study identifies the CD38-NAD<sup>+</sup> axis as an immunometabolic checkpoint in ITP. Anti-CD38 antibodies deplete NAD<sup>+</sup>, driving M1 macrophages and FcγRI upregulation, which increases platelet phagocytosis. Restoring NAD<sup>+</sup> via CD38 inhibition or NMN reprograms macrophages to a resting state and blocks platelet destruction without affecting humoral immunity. In 25 refractory ITP patients, low-dose NMN (450 mg bid × 2 weeks) was well tolerated: 20% achieved platelets ≥50×10<sup>9</sup>/L, and 52% maintained response at week 8, with stable immunoglobulin levels. Thus, targeting CD38-NAD<sup>+</sup> metabolism offers a non-antibody-depleting therapeutic strategy."
|
|
26
27
|
link: https://www.procellsystem.com/resources/publications
|
|
27
28
|
buttonText: View More Publications
|
|
@@ -63,7 +63,9 @@
|
|
|
63
63
|
|
|
64
64
|
<tr>
|
|
65
65
|
<td rowspan="2" style="padding-right: 12px;" class="image-box align-middle">
|
|
66
|
-
|
|
66
|
+
{{#information.image}}
|
|
67
|
+
<img src="{{.}}" />
|
|
68
|
+
{{/information.image}}
|
|
67
69
|
</td>
|
|
68
70
|
<td class="h-0 {{#information.link}}pb-24{{/information.link}}">
|
|
69
71
|
<p>{{information.content}}</p>
|
package/package.json
CHANGED