jbrowse-plugin-msaview 5.13.0 → 5.14.0

package/dist/MsaViewPanel/connectedDomains.d.ts

@@ -18,12 +18,14 @@ export interface ConnectedDomain {
      */
     regions: GenomeRegion[];
 }
-/** A categorical color object, spelt as a JBrowse display's `color` config. */
+/** A categorical color channel, spelt as a JBrowse display's `encoding.color`. */
 export interface DomainColor {
     field: 'accession';
-    domain: string[];
-    range: string[];
-    labels: string[];
+    scale: {
+        domain: string[];
+        range: string[];
+        names: string[];
+    };
 }
 export interface ConnectedDomains {
     /** largest first by residues covered */

package/dist/MsaViewPanel/connectedDomains.js

@@ -5,10 +5,10 @@
  * In grammar-of-graphics terms, `features` is the data and `kind` the field a
  * consumer filters its layers on (protein3d draws `domain` as cartoon and
  * `site` as side chains). `color` is the color channel: a categorical scale
- * over `accession`, whose `domain` lists the accessions, `range` the fills
- * the alignment draws them in, and `labels` what a guide (a legend) names
- * them. Every surface reads that one object: the genome track's display, the
- * structure's layers, its overview rows and each legend.
+ * over `accession`, whose `scale.domain` lists the accessions, `scale.range`
+ * the fills the alignment draws them in, and `scale.names` what a guide (a
+ * legend) names them. Every surface reads that one object: the genome track's
+ * display, the structure's layers, its overview rows and each legend.
  */
 import { isSiteType } from 'react-msaview';
 import { seqPosToGenomeRegions } from './msaCoordToGenomeCoord';
@@ -89,9 +89,11 @@ export function connectedDomains(model) {
         features: placed.map(p => p.feature),
         color: {
             field: 'accession',
-            domain: placed.map(p => p.feature.accession),
-            range: placed.map(p => p.fill),
-            labels: placed.map(p => p.feature.name),
+            scale: {
+                domain: placed.map(p => p.feature.accession),
+                range: placed.map(p => p.fill),
+                names: placed.map(p => p.feature.name),
+            },
         },
     };
 }

package/dist/MsaViewPanel/connectedDomains.test.js

@@ -53,17 +53,19 @@ describe('connectedDomains on a reverse-strand transcript', () => {
             ],
             color: {
                 field: 'accession',
-                domain: ['site'],
-                range: ['fill-site'],
-                labels: ['legend site'],
+                scale: {
+                    domain: ['site'],
+                    range: ['fill-site'],
+                    names: ['legend site'],
+                },
             },
         });
     });
     test('the longest comes first, in the features and the color domain alike', () => {
         const { features, color } = connectedDomains(source([annotation('site', 2, 4), annotation('domain', 1, 5)]));
         expect(features.map(d => d.accession)).toEqual(['domain', 'site']);
-        expect(color.domain).toEqual(['domain', 'site']);
-        expect(color.range).toEqual(['fill-domain', 'fill-site']);
+        expect(color.scale.domain).toEqual(['domain', 'site']);
+        expect(color.scale.range).toEqual(['fill-domain', 'fill-site']);
         expect(features[0].regions).toEqual([
             { refName: 'chr1', start: 100, end: 107 },
             { refName: 'chr1', start: 200, end: 208 },
@@ -108,7 +110,10 @@ describe('connectedDomains on a reverse-strand transcript', () => {
         expect(connectedDomains(source(annotations)).features).toEqual([]);
         expect(connectedDomains(source([annotation('domain', 1, 5)], { showDomains: false }))).toEqual({
             features: [],
-            color: { field: 'accession', domain: [], range: [], labels: [] },
+            color: {
+                field: 'accession',
+                scale: { domain: [], range: [], names: [] },
+            },
         });
     });
 });

package/dist/MsaViewPanel/domainTrack.d.ts

@@ -3,9 +3,9 @@ export declare function domainTrackId(viewId: string): string;
 /**
  * A session FeatureTrack drawing `domains` on the genome: one feature per
  * domain, one subfeature per region, so a domain spanning exons draws as boxes
- * joined across the intron. The display's color is the domains' color object,
- * a categorical scale over each feature's `accession`, so its key names each
- * color with its domain.
+ * joined across the intron. The display's `encoding.color` is the domains'
+ * color channel, a categorical scale over each feature's `accession`, so its
+ * key names each color with its domain.
  */
 export declare function domainTrackConf({ viewId, assemblyName, name, strand, domains, }: {
     viewId: string;
@@ -73,12 +73,18 @@ export declare function domainTrackConf({ viewId, assemblyName, name, strand, do
     displays: {
         type: string;
         displayId: string;
-        color: {
-            title: string;
-            field: "accession";
-            domain: string[];
-            range: string[];
-            labels: string[];
+        encoding: {
+            color: {
+                legend: {
+                    title: string;
+                };
+                field: "accession";
+                scale: {
+                    domain: string[];
+                    range: string[];
+                    names: string[];
+                };
+            };
         };
     }[];
 };

package/dist/MsaViewPanel/domainTrack.js

@@ -4,9 +4,9 @@ export function domainTrackId(viewId) {
 /**
  * A session FeatureTrack drawing `domains` on the genome: one feature per
  * domain, one subfeature per region, so a domain spanning exons draws as boxes
- * joined across the intron. The display's color is the domains' color object,
- * a categorical scale over each feature's `accession`, so its key names each
- * color with its domain.
+ * joined across the intron. The display's `encoding.color` is the domains'
+ * color channel, a categorical scale over each feature's `accession`, so its
+ * key names each color with its domain.
  */
 export function domainTrackConf({ viewId, assemblyName, name, strand, domains, }) {
     const trackId = domainTrackId(viewId);
@@ -44,7 +44,9 @@ export function domainTrackConf({ viewId, assemblyName, name, strand, domains, }
             {
                 type: 'LinearBasicDisplay',
                 displayId: `${trackId}-LinearBasicDisplay`,
-                color: { ...domains.color, title: 'Domains' },
+                encoding: {
+                    color: { ...domains.color, legend: { title: 'Domains' } },
+                },
             },
         ],
     };

package/dist/MsaViewPanel/domainTrack.test.js

@@ -20,9 +20,11 @@ const domains = {
     ],
     color: {
         field: 'accession',
-        domain: ['cd1', 'cd2'],
-        range: ['#1b9e77', '#d95f02'],
-        labels: ['Hb beta-like', 'heme binding site'],
+        scale: {
+            domain: ['cd1', 'cd2'],
+            range: ['#1b9e77', '#d95f02'],
+            names: ['Hb beta-like', 'heme binding site'],
+        },
     },
 };
 const conf = domainTrackConf({
@@ -49,13 +51,15 @@ test('one feature per domain, one subfeature per region, spanning them all', ()
         [200, 208],
     ]);
 });
-test('the display paints through the domains color object and names each in the key', () => {
-    expect(conf.displays[0].color).toEqual({
+test('the display paints through the domains color channel and titles its key', () => {
+    expect(conf.displays[0].encoding.color).toEqual({
         field: 'accession',
-        domain: ['cd1', 'cd2'],
-        range: ['#1b9e77', '#d95f02'],
-        labels: ['Hb beta-like', 'heme binding site'],
-        title: 'Domains',
+        scale: {
+            domain: ['cd1', 'cd2'],
+            range: ['#1b9e77', '#d95f02'],
+            names: ['Hb beta-like', 'heme binding site'],
+        },
+        legend: { title: 'Domains' },
     });
 });
 test('a MAF view knows no strand, and the features carry none', () => {

package/dist/MsaViewPanel/model.test.js

@@ -243,20 +243,25 @@ describe('connectedDomains', () => {
             ],
             color: {
                 field: 'accession',
-                domain: ['cd1', 'cd2'],
-                range: [fills.get('QUERY:cd1'), fills.get('QUERY:cd2')],
-                labels: ['Hb beta-like', 'heme binding site'],
+                scale: {
+                    domain: ['cd1', 'cd2'],
+                    range: [fills.get('QUERY:cd1'), fills.get('QUERY:cd2')],
+                    names: ['Hb beta-like', 'heme binding site'],
+                },
             },
         });
     });
     test('follows the overlay and the legend filter', () => {
         const model = domainView();
         model.setFilter('cd2', false);
-        expect(model.connectedDomains.color.domain).toEqual(['cd1']);
+        expect(model.connectedDomains.color.scale.domain).toEqual(['cd1']);
         model.setShowDomains(false);
         expect(model.connectedDomains).toEqual({
             features: [],
-            color: { field: 'accession', domain: [], range: [], labels: [] },
+            color: {
+                field: 'accession',
+                scale: { domain: [], range: [], names: [] },
+            },
         });
     });
 });

package/dist/chunks/{model-T6Q2NL4X.js → model-ZXS5732V.js}

@@ -8,5 +8,5 @@ ${e??t}`,...s].join(`
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Try the NCBI BLAST tab, which needs no gene identifier.`);let i=await br(o.geneId,n),s=await nt({geneId:o.geneId,onProgress:e,signal:n,...r});return{geneId:o.geneId,representative:i,rows:s}}var Dr={ncbi:"NCBI",panther:"PANTHER",uniref:"UniProt"};async function yr({geneCandidates:A,identity:t,referenceProteomesOnly:e,...n}){let r=await Dt({candidates:A,identity:t,referenceProteomesOnly:e,...n});return{geneId:r.query.id,representative:{accession:r.query.accession,sequence:r.query.sequence},rows:r.rows,warning:r.warning}}async function Nr({geneCandidates:A,...t}){let e=await St({candidates:A,...t});return{geneId:e.query?.geneRef??e.matched,representative:e.query,rows:e.rows}}async function kr(A,t,e){let n;try{let r=(await sA([A],e)).get(A);n=r?.commonName??r?.sciname}catch(r){if(F(r))throw r;console.warn("[msaview-orthologs] taxonomy name lookup failed:",r)}return aA([...t.map(r=>r.label),`${n??"query"}_query`]).at(-1)}async function br(A,t){try{return await tt(A,t)}catch(e){if(F(e))throw 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r[o++]=1<<24|64<<16|0,r[o++]=1<<24|64<<16|0,s.bits=1,0;for(C=1;C<Q&&x[C]===0;C++);for(I<C&&(I=C),u=1,a=1;a<=BA;a++)if(u<<=1,u-=x[a],u<0)return-1;if(u>0&&(A===Kt||Q!==1))return-1;for(N[1]=0,a=1;a<BA;a++)N[a+1]=N[a]+x[a];for(g=0;g<n;g++)t[e+g]!==0&&(i[N[t[e+g]]++]=g);if(A===Kt?(k=L=i,D=19):A===ue?(k=vr,w-=257,L=Lr,U-=257,D=256):(k=Ur,L=qr,D=-1),p=0,g=0,a=C,f=o,d=I,h=0,E=-1,l=1<<I,y=l-1,A===ue&&l>Ht||A===Tt&&l>Pt)return 1;for(;;){tA=a-h,i[g]<D?(q=0,T=i[g]):i[g]>D?(q=L[U+i[g]],T=k[w+i[g]]):(q=96,T=0),m=1<<a-h,B=1<<d,C=B;do B-=m,r[f+(p>>h)+B]=tA<<24|q<<16|T|0;while(B!==0);for(m=1<<a-1;p&m;)m>>=1;if(m!==0?(p&=m-1,p+=m):p=0,g++,--x[a]===0){if(a===Q)break;a=t[e+i[g]]}if(a>I&&(p&y)!==E){for(h===0&&(h=I),f+=C,d=a-h,u=1<<d;d+h<Q&&(u-=x[d+h],!(u<=0));)d++,u<<=1;if(l+=1<<d,A===ue&&l>Ht||A===Tt&&l>Pt)return 1;E=p&y,r[E]=I<<24|d<<16|f-o|0}}return p!==0&&(r[f+p]=a-h<<24|64<<16|0),s.bits=I,0}var _r=0,un=1,ln=2,Ot=4,Yr=5,TA=6,eA=0,Hr=1,Pr=2,v=-2,mn=-3,De=-4,Kr=-5,Zt=8,hn=1,Xt=2,Vt=3,jt=4,Wt=5,zt=6,$t=7,An=8,en=9,tn=10,XA=11,H=12,le=13,nn=14,me=15,on=16,rn=17,an=18,sn=19,OA=20,ZA=21,gn=22,cn=23,In=24,Qn=25,Bn=26,he=27,Cn=28,En=29,M=30,ye=31,Tr=32,Or=852,Zr=592;function dn(A){return(A>>>24&255)+(A>>>8&65280)+((A&65280)<<8)+((A&255)<<24)}function Xr(){this.mode=0,this.last=!1,this.wrap=0,this.havedict=!1,this.flags=0,this.dmax=0,this.check=0,this.total=0,this.head=null,this.wbits=0,this.wsize=0,this.whave=0,this.wnext=0,this.window=null,this.hold=0,this.bits=0,this.length=0,this.offset=0,this.extra=0,this.lencode=null,this.distcode=null,this.lenbits=0,this.distbits=0,this.ncode=0,this.nlen=0,this.ndist=0,this.have=0,this.next=null,this.lens=X(320),this.work=X(288),this.lendyn=null,this.distdyn=null,this.sane=0,this.back=0,this.was=0}function Vr(A){var t;return!A||!A.state?v:(t=A.state,A.total_in=A.total_out=t.total=0,A.msg="",t.wrap&&(A.adler=t.wrap&1),t.mode=hn,t.last=0,t.havedict=0,t.dmax=32768,t.head=null,t.hold=0,t.bits=0,t.lencode=t.lendyn=$(Or),t.distcode=t.distdyn=$(Zr),t.sane=1,t.back=-1,eA)}function jr(A){var t;return!A||!A.state?v:(t=A.state,t.wsize=0,t.whave=0,t.wnext=0,Vr(A))}function Wr(A,t){var e,n;return!A||!A.state||(n=A.state,t<0?(e=0,t=-t):(e=(t>>4)+1,t<48&&(t&=15)),t&&(t<8||t>15))?v:(n.window!==null&&n.wbits!==t&&(n.window=null),n.wrap=e,n.wbits=t,jr(A))}function wn(A,t){var e,n;return A?(n=new Xr,A.state=n,n.window=null,e=Wr(A,t),e!==eA&&(A.state=null),e):v}var fn=!0,we,pe;function zr(A){if(fn){var t;for(we=$(512),pe=$(32),t=0;t<144;)A.lens[t++]=8;for(;t<256;)A.lens[t++]=9;for(;t<280;)A.lens[t++]=7;for(;t<288;)A.lens[t++]=8;for(AA(un,A.lens,0,288,we,0,A.work,{bits:9}),t=0;t<32;)A.lens[t++]=5;AA(ln,A.lens,0,32,pe,0,A.work,{bits:5}),fn=!1}A.lencode=we,A.lenbits=9,A.distcode=pe,A.distbits=5}function pn(A,t,e,n){var r,o=A.state;return o.window===null&&(o.wsize=1<<o.wbits,o.wnext=0,o.whave=0,o.window=Y(o.wsize)),n>=o.wsize?(_(o.window,t,e-o.wsize,o.wsize,0),o.wnext=0,o.whave=o.wsize):(r=o.wsize-o.wnext,r>n&&(r=n),_(o.window,t,e-n,r,o.wnext),n-=r,n?(_(o.window,t,e-n,n,0),o.wnext=n,o.whave=o.wsize):(o.wnext+=r,o.wnext===o.wsize&&(o.wnext=0),o.whave<o.wsize&&(o.whave+=r))),0}function Dn(A,t){var e,n,r,o,i,s,c,a,g,C,Q,I,d,h,u=0,l,p,m,B,E,y,f,k,w=Y(4),D,x,N=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15];if(!A||!A.state||!A.output||!A.input&&A.avail_in!==0)return v;e=A.state,e.mode===H&&(e.mode=le),i=A.next_out,r=A.output,c=A.avail_out,o=A.next_in,n=A.input,s=A.avail_in,a=e.hold,g=e.bits,C=s,Q=c,k=eA;A:for(;;)switch(e.mode){case hn:if(e.wrap===0){e.mode=le;break}for(;g<16;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}if(e.wrap&2&&a===35615){e.check=0,w[0]=a&255,w[1]=a>>>8&255,e.check=J(e.check,w,2,0),a=0,g=0,e.mode=Xt;break}if(e.flags=0,e.head&&(e.head.done=!1),!(e.wrap&1)||(((a&255)<<8)+(a>>8))%31){A.msg="incorrect header check",e.mode=M;break}if((a&15)!==Zt){A.msg="unknown compression method",e.mode=M;break}if(a>>>=4,g-=4,f=(a&15)+8,e.wbits===0)e.wbits=f;else if(f>e.wbits){A.msg="invalid window size",e.mode=M;break}e.dmax=1<<f,A.adler=e.check=1,e.mode=a&512?tn:H,a=0,g=0;break;case Xt:for(;g<16;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}if(e.flags=a,(e.flags&255)!==Zt){A.msg="unknown compression method",e.mode=M;break}if(e.flags&57344){A.msg="unknown header flags set",e.mode=M;break}e.head&&(e.head.text=a>>8&1),e.flags&512&&(w[0]=a&255,w[1]=a>>>8&255,e.check=J(e.check,w,2,0)),a=0,g=0,e.mode=Vt;case Vt:for(;g<32;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}e.head&&(e.head.time=a),e.flags&512&&(w[0]=a&255,w[1]=a>>>8&255,w[2]=a>>>16&255,w[3]=a>>>24&255,e.check=J(e.check,w,4,0)),a=0,g=0,e.mode=jt;case jt:for(;g<16;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}e.head&&(e.head.xflags=a&255,e.head.os=a>>8),e.flags&512&&(w[0]=a&255,w[1]=a>>>8&255,e.check=J(e.check,w,2,0)),a=0,g=0,e.mode=Wt;case Wt:if(e.flags&1024){for(;g<16;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}e.length=a,e.head&&(e.head.extra_len=a),e.flags&512&&(w[0]=a&255,w[1]=a>>>8&255,e.check=J(e.check,w,2,0)),a=0,g=0}else e.head&&(e.head.extra=null);e.mode=zt;case zt:if(e.flags&1024&&(I=e.length,I>s&&(I=s),I&&(e.head&&(f=e.head.extra_len-e.length,e.head.extra||(e.head.extra=new Array(e.head.extra_len)),_(e.head.extra,n,o,I,f)),e.flags&512&&(e.check=J(e.check,n,I,o)),s-=I,o+=I,e.length-=I),e.length))break A;e.length=0,e.mode=$t;case $t:if(e.flags&2048){if(s===0)break A;I=0;do f=n[o+I++],e.head&&f&&e.length<65536&&(e.head.name+=String.fromCharCode(f));while(f&&I<s);if(e.flags&512&&(e.check=J(e.check,n,I,o)),s-=I,o+=I,f)break A}else e.head&&(e.head.name=null);e.length=0,e.mode=An;case An:if(e.flags&4096){if(s===0)break A;I=0;do f=n[o+I++],e.head&&f&&e.length<65536&&(e.head.comment+=String.fromCharCode(f));while(f&&I<s);if(e.flags&512&&(e.check=J(e.check,n,I,o)),s-=I,o+=I,f)break A}else e.head&&(e.head.comment=null);e.mode=en;case en:if(e.flags&512){for(;g<16;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}if(a!==(e.check&65535)){A.msg="header crc mismatch",e.mode=M;break}a=0,g=0}e.head&&(e.head.hcrc=e.flags>>9&1,e.head.done=!0),A.adler=e.check=0,e.mode=H;break;case tn:for(;g<32;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}A.adler=e.check=dn(a),a=0,g=0,e.mode=XA;case XA:if(e.havedict===0)return A.next_out=i,A.avail_out=c,A.next_in=o,A.avail_in=s,e.hold=a,e.bits=g,Pr;A.adler=e.check=1,e.mode=H;case H:if(t===Yr||t===TA)break A;case le:if(e.last){a>>>=g&7,g-=g&7,e.mode=he;break}for(;g<3;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}switch(e.last=a&1,a>>>=1,g-=1,a&3){case 0:e.mode=nn;break;case 1:if(zr(e),e.mode=OA,t===TA){a>>>=2,g-=2;break A}break;case 2:e.mode=rn;break;case 3:A.msg="invalid block type",e.mode=M}a>>>=2,g-=2;break;case nn:for(a>>>=g&7,g-=g&7;g<32;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}if((a&65535)!==(a>>>16^65535)){A.msg="invalid stored block lengths",e.mode=M;break}if(e.length=a&65535,a=0,g=0,e.mode=me,t===TA)break A;case me:e.mode=on;case on:if(I=e.length,I){if(I>s&&(I=s),I>c&&(I=c),I===0)break A;_(r,n,o,I,i),s-=I,o+=I,c-=I,i+=I,e.length-=I;break}e.mode=H;break;case rn:for(;g<14;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}if(e.nlen=(a&31)+257,a>>>=5,g-=5,e.ndist=(a&31)+1,a>>>=5,g-=5,e.ncode=(a&15)+4,a>>>=4,g-=4,e.nlen>286||e.ndist>30){A.msg="too many length or distance symbols",e.mode=M;break}e.have=0,e.mode=an;case an:for(;e.have<e.ncode;){for(;g<3;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}e.lens[N[e.have++]]=a&7,a>>>=3,g-=3}for(;e.have<19;)e.lens[N[e.have++]]=0;if(e.lencode=e.lendyn,e.lenbits=7,D={bits:e.lenbits},k=AA(_r,e.lens,0,19,e.lencode,0,e.work,D),e.lenbits=D.bits,k){A.msg="invalid code lengths set",e.mode=M;break}e.have=0,e.mode=sn;case sn:for(;e.have<e.nlen+e.ndist;){for(;u=e.lencode[a&(1<<e.lenbits)-1],l=u>>>24,p=u>>>16&255,m=u&65535,!(l<=g);){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}if(m<16)a>>>=l,g-=l,e.lens[e.have++]=m;else{if(m===16){for(x=l+2;g<x;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}if(a>>>=l,g-=l,e.have===0){A.msg="invalid bit length repeat",e.mode=M;break}f=e.lens[e.have-1],I=3+(a&3),a>>>=2,g-=2}else if(m===17){for(x=l+3;g<x;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}a>>>=l,g-=l,f=0,I=3+(a&7),a>>>=3,g-=3}else{for(x=l+7;g<x;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}a>>>=l,g-=l,f=0,I=11+(a&127),a>>>=7,g-=7}if(e.have+I>e.nlen+e.ndist){A.msg="invalid bit length repeat",e.mode=M;break}for(;I--;)e.lens[e.have++]=f}}if(e.mode===M)break;if(e.lens[256]===0){A.msg="invalid code -- missing end-of-block",e.mode=M;break}if(e.lenbits=9,D={bits:e.lenbits},k=AA(un,e.lens,0,e.nlen,e.lencode,0,e.work,D),e.lenbits=D.bits,k){A.msg="invalid literal/lengths set",e.mode=M;break}if(e.distbits=6,e.distcode=e.distdyn,D={bits:e.distbits},k=AA(ln,e.lens,e.nlen,e.ndist,e.distcode,0,e.work,D),e.distbits=D.bits,k){A.msg="invalid distances set",e.mode=M;break}if(e.mode=OA,t===TA)break A;case OA:e.mode=ZA;case ZA:if(s>=6&&c>=258){A.next_out=i,A.avail_out=c,A.next_in=o,A.avail_in=s,e.hold=a,e.bits=g,fe(A,Q),i=A.next_out,r=A.output,c=A.avail_out,o=A.next_in,n=A.input,s=A.avail_in,a=e.hold,g=e.bits,e.mode===H&&(e.back=-1);break}for(e.back=0;u=e.lencode[a&(1<<e.lenbits)-1],l=u>>>24,p=u>>>16&255,m=u&65535,!(l<=g);){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}if(p&&(p&240)===0){for(B=l,E=p,y=m;u=e.lencode[y+((a&(1<<B+E)-1)>>B)],l=u>>>24,p=u>>>16&255,m=u&65535,!(B+l<=g);){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}a>>>=B,g-=B,e.back+=B}if(a>>>=l,g-=l,e.back+=l,e.length=m,p===0){e.mode=Bn;break}if(p&32){e.back=-1,e.mode=H;break}if(p&64){A.msg="invalid literal/length code",e.mode=M;break}e.extra=p&15,e.mode=gn;case gn:if(e.extra){for(x=e.extra;g<x;){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}e.length+=a&(1<<e.extra)-1,a>>>=e.extra,g-=e.extra,e.back+=e.extra}e.was=e.length,e.mode=cn;case cn:for(;u=e.distcode[a&(1<<e.distbits)-1],l=u>>>24,p=u>>>16&255,m=u&65535,!(l<=g);){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}if((p&240)===0){for(B=l,E=p,y=m;u=e.distcode[y+((a&(1<<B+E)-1)>>B)],l=u>>>24,p=u>>>16&255,m=u&65535,!(B+l<=g);){if(s===0)break A;s--,a+=n[o++]<<g,g+=8}a>>>=B,g-=B,e.back+=B}if(a>>>=l,g-=l,e.back+=l,p&64){A.msg="invalid distance code",e.mode=M;break}e.offset=m,e.extra=p&15,e.mode=In;case 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C=`${o}-${g}`;return{uniqueId:C,refName:a[0].refName,start:Math.min(...a.map(Q=>Q.start)),end:Math.max(...a.map(Q=>Q.end)),...i,type:"protein_domain",name:s,accession:c,subfeatures:a.map((Q,I)=>({uniqueId:`${C}-${I}`,refName:Q.refName,start:Q.start,end:Q.end,...i,type:"protein_domain_part"}))}})},displays:[{type:"LinearBasicDisplay",displayId:`${o}-LinearBasicDisplay`,color:{...r.color,title:"Domains"}}]}}var vo=R(To()),qe=R(nA()),Lo=R(Zo()),Uo=R(ne()),ee=R(LA());function Go(A){return A.replace(/\.\d+$/,"")}function Vi(A,t){let e=Go(t);return[A.get("name"),A.get("id"),A.get("transcript_id"),A.id()].some(n=>typeof n=="string"&&(n===t||Go(n)===e))}function Jo(A){return A.map(t=>({assemblyName:t.assemblyName,refName:t.refName,start:Math.floor(t.start),end:Math.ceil(t.end)}))}function ji(A){let t=Jo(A.dynamicBlocks?.contentBlocks??[]),e=Jo(A.displayedRegions);return t.length>0?[t,e]:[e]}function qo(A){return A.filter(t=>t.type==="FeatureTrack")}async function Wi(A,t){let 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Open the gene track that carries it, and make sure the view is on its locus.`);let s=await zi(A,i);if(!s)throw new Error(`Transcript "${t}" has no CDS to translate`);if(!r())return;let c=i.toJSON();(0,ee.transaction)(()=>{A.setProgress(""),e&&!e.proteinSequence&&A.setBlastParams({...e,selectedTranscript:c,proteinSequence:s}),n&&!n.proteinSequence&&A.setOrthologParams({...n,selectedTranscript:c,proteinSequence:s}),A.setConnectedFeature(c)})}catch(i){console.error(i),r()&&(A.setProgress(""),A.setError(i))}}function _o(A){let{connectedTranscript:t,connectedFeature:e,connectedView:n,blastParams:r,orthologParams:o}=A;if(!t||e||!n?.initialized||n.tracks.length===0)return;let i=(Ue.get(A)??0)+1;Ue.set(A,i),(0,ee.untracked)(()=>{$i({self:A,transcriptId:t,blastParams:r,orthologParams:o,isCurrent:()=>(0,Uo.isAlive)(A)&&Ue.get(A)===i})})}var Ho=R(nA());var Yo="session-highlights";function Aa({start:A,end:t},e,n){let r=new Set;if(e.kind==="maf")for(let o=Math.max(A,e.start);o<Math.min(t,e.end);o++)r.add(o-e.start);else for(let o=A;o<t;o++){let i=e.map.g2p[o];i!==void 0&&r.add(i-n)}return[...r].filter(o=>o>=0).sort((o,i)=>o-i)}function ea({highlights:A,onGenome:t,querySeqName:e,querySeqOffset:n,sameAssembly:r,sameRefName:o,labels:i}){return A.flatMap(s=>{if(!r(s.assemblyName)||!o(s.refName))return[];let c=[];for(let a of Aa(s,t,n)){let g=c.at(-1);g?.end===a?g.end=a+1:c.push({row:e,start:a+1,end:a+1,...i&&s.label?{label:s.label}:{},...s.color?{color:s.color}:{}})}return c})}function ta(A){return!("highlightLabelsVisible"in A&&A.highlightLabelsVisible===!1)}function Po(A){return()=>{let t=(0,Ho.getSession)(A),{connectedView:e,transcriptToMsaMap:n,mafRegion:r}=A,o=r?.assemblyName??e?.assemblyNames[0],{assemblyManager:i}=t,s=o?i.get(o):void 0,c=r?{kind:"maf",...r}:n?{kind:"transcript",map:n}:void 0;if(!t.highlightsVisible||!t.highlights.length||!c||!s?.initialized||!oA(A)){A.clearHighlight(Yo);return}let a=s.getCanonicalRefName(c.kind==="maf"?c.refName:c.map.refName);A.applyHighlight(Yo,ea({highlights:t.highlights,onGenome:c,querySeqName:A.querySeqName,querySeqOffset:A.querySeqOffset,sameAssembly:g=>i.get(g)===s,sameRefName:g=>s.getCanonicalRefName(g)===a,labels:ta(t)}))}}var Sg=["ncbi","panther","uniref"];function na(){return b.types.compose(Ko.BaseViewModel,rt(),b.types.model("MsaView",{connectedViewId:b.types.maybe(b.types.string),connectedFeature:b.types.frozen(),connectedTranscript:b.types.maybe(b.types.string),blastParams:b.types.frozen(),orthologParams:b.types.frozen(),querySeqName:b.types.stripDefault(b.types.string,"QUERY"),querySeqOffset:b.types.stripDefault(b.types.number,0),uniprotId:b.types.maybe(b.types.string),zoomToBaseLevel:b.types.stripDefault(b.types.boolean,!1),init:b.types.frozen(),dataStoreId:b.types.maybe(b.types.string),launchCompleted:!1,mafRegion:b.types.frozen(),embeddedMode:!0,domainsOnGenome:b.types.stripDefault(b.types.boolean,!1)})).volatile(()=>({rid:void 0,progress:"",loadingStoredData:!1,isStoringData:!1,lastStoredData:void 0,ownsDataStoreRow:!1,launchController:void 0,domainsRequested:!1})).views(A=>({get transcriptToMsaMap(){return A.connectedFeature?Qo(A.connectedFeature):void 0},get connectedView(){let{views:t}=(0,K.getSession)(A);return t.find(e=>e.id===A.connectedViewId)}})).views(A=>({get connectedHoverHighlights(){let{mouseCol:t}=A;return t===void 0?[]:Ae({model:A,coord:t})},get connectedClickHighlights(){let{mouseClickCol:t}=A;return t===void 0?[]:Ae({model:A,coord:t})},get connectedHighlights(){return[...this.connectedHoverHighlights,...this.connectedClickHighlights]},get connectedDomains(){return Ro(A)}})).views(A=>({get hostRestoresData(){let{msaIndexedLocation:t,msaName:e}=A.init??{};return A.hostCarriesData||!!(t&&e)},get unsavedDocuments(){let{data:t,init:e}=A,n=(0,b.getSnapshot)(t),r=(o,i)=>{let s=t[o];return s&&!i&&!n[o]?s:void 0};return{msa:r("msa",A.msaFilehandle??e?.msaIndexedLocation),tree:r("tree",A.treeFilehandle),treeMetadata:r("treeMetadata",A.treeMetadataFilehandle),gff:r("gff",A.gffFilehandle)}}})).actions(A=>({setZoomToBaseLevel(t){A.zoomToBaseLevel=t},setProgress(t){A.progress=t},setRid(t){A.rid=t},setBlastParams(t){A.blastParams=t},setConnectedFeature(t){A.connectedFeature=t},setOrthologParams(t){A.orthologParams=t},setInit(t){A.init=t},setQuerySeqName(t){A.querySeqName=t},setUniprotId(t){A.uniprotId=t},setDataStoreId(t){A.dataStoreId=t},setLaunchCompleted(t){A.launchCompleted=t},setLoadingStoredData(t){A.loadingStoredData=t},setIsStoringData(t){A.isStoringData=t},setLastStoredData(t){A.lastStoredData=t},setOwnsDataStoreRow(t){A.ownsDataStoreRow=t},setLaunchController(t){A.launchController=t},cancelLaunch(){A.launchController?.abort(),A.launchController=void 0,A.blastParams=void 0,A.orthologParams=void 0,A.init=void 0,A.launchCompleted=!1,A.progress="",A.rid=void 0,A.error=void 0},retryLaunch(){A.launchController?.abort(),A.launchController=void 0,A.progress="",A.rid=void 0,A.error=void 0,A.launchCompleted=!1,A.blastParams&&(A.blastParams={...A.blastParams}),A.orthologParams&&(A.orthologParams={...A.orthologParams}),A.init&&(A.init={...A.init})},setDomainsRequested(t){A.domainsRequested=t},setDomainsOnGenome(t){A.domainsOnGenome=t},showDomainsOnGenome(){let t=(0,K.getSession)(A),{connectedView:e,connectedDomains:n,connectedFeature:r}=A,o=e?.assemblyNames[0];if(!e||!o||n.features.length===0||!(0,K.isSessionWithAddSessionTrack)(t))return;let i=r,s=[i?.gene_name,i?.gene,i?.name].find(g=>typeof g=="string"&&g!==""),c=Fo({viewId:A.id,assemblyName:o,name:`${s??A.querySeqName} domains (from the alignment)`,strand:A.mafRegion?void 0:A.transcriptToMsaMap?.strand,domains:n}),a=(0,K.isSessionWithSessionTracks)(t)?t.sessionTracks.find(g=>g.trackId===c.trackId):void 0;a&&(0,K.isSessionWithDeleteTrackConf)(t)&&t.deleteTrackConf(a),t.addSessionTrackConf(c)&&e.launchTrack(c.trackId)},handleMsaClick(t){let{connectedView:e,zoomToBaseLevel:n}=A,r=xo({model:A,coord:t});!r||!e||(n?e.navTo(r):e.centerAt(r.start,r.refName))}})).actions(A=>{let t=A.setMouseClickPos.bind(A);return{setMouseClickPos(e,n){t(e,n),e!==void 0&&A.handleMsaClick(e)}}}).actions(A=>{let t=A.reset.bind(A);return{reset(){let{displayName:e,minimized:n,zoomToBaseLevel:r}=A;t(),e!==void 0&&A.setDisplayName(e),A.setMinimized(n),A.setZoomToBaseLevel(r),A.setDomainsRequested(!1),A.setLastStoredData(void 0),A.setOwnsDataStoreRow(!1)}}}).views(A=>{let t=A.menuItems.bind(A);return{menuItems(){return[...t(),{label:"Zoom to base level on click?",type:"checkbox",checked:A.zoomToBaseLevel,onClick:()=>{A.setZoomToBaseLevel(!A.zoomToBaseLevel)}},...A.connectedView&&A.connectedDomains.features.length>0?[{label:"Show domains on the genome",onClick:()=>{A.showDomainsOnGenome()}}]:[]]}}}).actions(A=>({afterCreate(){So(),(0,b.addDisposer)(A,()=>{A.launchController?.abort()}),mo(A);for(let t of[ho,_o,Do,po,No,yo,Mo])(0,b.addDisposer)(A,(0,RA.autorun)(()=>{t(A)}));(0,b.addDisposer)(A,(0,RA.autorun)(ko(A))),(0,b.addDisposer)(A,(0,RA.autorun)(bo(A))),(0,b.addDisposer)(A,(0,RA.autorun)(Po(A)))}}))}export{na as default,Sg as orthologSources};
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+`)){let[r,o,i]=n.split("	");if(r&&Hn(r)===e)return{offset:Number(o),length:Number(i)}}}var Tn=R(nA());function On({model:A}){let{assemblyManager:t,hovered:e}=(0,Tn.getSession)(A),{transcriptToMsaMap:n,connectedView:r,mafRegion:o}=A;if(!r?.initialized||!He(e)||!oA(A))return;let{coord:i,refName:s}=e.hoverPosition,c=i-1,a=t.get(o?.assemblyName??r.assemblyNames[0]??""),g=Q=>(a?.initialized?a.getCanonicalRefName(Q):void 0)??Q,C=g(s);if(o)return C!==g(o.refName)||!r.assemblyNames.includes(o.assemblyName)||c<o.start||c>=o.end?void 0:Ye(A,c-o.start);if(n&&C===g(n.refName)){let Q=n.g2p[c];if(Q!==void 0)return GA(A,Q)}}var mi="jbrowse-msaview-domain-cache-v3",hi=["jbrowse-msaview-domain-cache","jbrowse-msaview-domain-cache-v2"],$A="domains",wi=1,pi=rA(mi,wi,A=>{A.objectStoreNames.contains($A)||A.createObjectStore($A,{keyPath:"accession"})}),Zn=!1;function Xn(){if(!Zn){Zn=!0;for(let A of hi)Promise.resolve().then(()=>je(A)).catch(()=>{})}return pi()}function Vn(A){return iA("domain cache read",async()=>{let e=(await Xn()).transaction($A,"readonly"),n=await Promise.all(A.map(r=>e.store.get(r)));return await e.done,n},[])}function jn(A){return iA("domain cache write",async()=>{let e=(await Xn()).transaction($A,"readwrite");for(let n of A)await e.store.put(n);await e.done},void 0)}function j(A,t){let e=new RegExp(`<${t}>(.*?)</${t}>`,"s").exec(A)?.[1];return e===void 0?void 0:At(e)}function Di(A){let t={},e=/<GBQualifier>([\s\S]*?)<\/GBQualifier>/g,n;for(;(n=e.exec(A))!==null;){let r=j(n[1],"GBQualifier_name"),o=j(n[1],"GBQualifier_value");r&&o!==void 0&&t[r]===void 0&&(t[r]=o)}return t}function yi(A){let t=[],e=/<GBInterval>([\s\S]*?)<\/GBInterval>/g,n;for(;(n=e.exec(A))!==null;){let r=n[1],o=j(r,"GBInterval_from"),i=j(r,"GBInterval_to"),s=j(r,"GBInterval_point");o&&i?t.push({start:Number(o),end:Number(i)}):s&&t.push({start:Number(s),end:Number(s)})}return t}function Ni(A){let t=j(A,"GBFeature_key"),e=Di(A),n=e.db_xref,r=yi(A);if((t==="Region"||t==="Site")&&n?.startsWith("CDD:")&&r.length>0){let o=n.replace("CDD:",""),i=t==="Region",s=e.note?.split(/[[(]/)[0]?.trim(),c=i?e.region_name??o:s||e.site_type||"site",a=i?o:`${o}:${c}`;return{signature:{entry:{name:c,description:e.note??c,accession:a}},locations:r,featureType:t}}}function ki(A){let t=new Map,e=/<GBSeq>([\s\S]*?)<\/GBSeq>/g,n;for(;(n=e.exec(A))!==null;){let r=n[1],o=[],i=/<GBFeature>([\s\S]*?)<\/GBFeature>/g,s;for(;(s=i.exec(r))!==null;){let c=Ni(s[1]);c&&o.push(c)}for(let c of[j(r,"GBSeq_accession-version"),j(r,"GBSeq_primary-accession")])c&&t.set(c,o)}return t}async function Wn(A,t){let e=[...new Set(A)].filter(Boolean),n=new Map,r=await Vn(e),o=[];e.forEach((c,a)=>{let g=r[a];g?n.set(c,g.matches):o.push(c)});let i=[],s=100;for(let c=0;c<o.length;c+=s){let a=o.slice(c,c+s),g;try{g=await $e(ze({db:"protein",id:a.join(","),rettype:"gp",retmode:"xml"}),{signal:t})}catch(Q){if(F(Q))throw Q;console.warn("[msaview-domains] efetch failed, keeping what loaded:",Q);break}let C=ki(g);for(let Q of a){let I=C.get(Q);I!==void 0&&(n.set(Q,I),i.push({accession:Q,matches:I}))}}return i.length>0&&await jn(i),n}async function zn(A,t){let e=Object.entries(A.rowData).flatMap(([o,i])=>i?.Accession?[{rowName:o,accession:i.Accession}]:[]);if(e.length===0)throw new Error("No NCBI accessions found in alignment rows");let n=await Wn(e.map(o=>o.accession),t),r=e.flatMap(({rowName:o,accession:i})=>(n.get(i)??[]).flatMap(({signature:s,locations:c,featureType:a})=>s.entry?c.map(({start:g,end:C})=>({id:o,accession:s.entry.accession,name:s.entry.name,description:s.entry.description,featureType:a,start:g,end:C})):[]));if(r.length===0)throw new Error("No CDD domain annotations found for these proteins");A.setAnnotations(r)}var bi="jbrowse-msaview-data",Si=1,uA="msa-data",Je=rA(bi,Si,A=>{A.objectStoreNames.contains(uA)||A.createObjectStore(uA,{keyPath:"id"}).createIndex("timestamp","timestamp",{unique:!1})});function $n(){return`msa-${Date.now()}-${Math.random().toString(36).slice(2,11)}`}async function Ao(A,t){try{let e=await Je(),n={...t,id:A,timestamp:Date.now()};return await e.put(uA,n),!0}catch(e){return console.warn("Failed to store MSA data:",e),!1}}async function eo(A){let t=await Je(),e=await t.get(uA,A);if(!e)return;try{await t.put(uA,{...e,timestamp:Date.now()})}catch(i){console.warn("Failed to refresh MSA data timestamp:",i)}let{id:n,timestamp:r,...o}=e;return o}async function to(A=10080*60*1e3){try{let t=await Je(),e=Date.now()-A,o=await t.transaction(uA,"readwrite").store.index("timestamp").openCursor(IDBKeyRange.upperBound(e)),i=0;for(;o;)await o.delete(),i++,o=await o.continue();return i}catch(t){return console.warn("Failed to cleanup old MSA data:",t),0}}var no=R(nA()),oo=R(LA());function Mi(A){if(!(A.rows.length<2))try{A.calculateNeighborJoiningTreeFromMSA()}catch(t){console.error(t);try{(0,no.getSession)(A).notify(`The alignment loaded, but no tree was built. ${t instanceof Error?t.message:String(t)}`,"warning")}catch(e){console.error(e)}}}function ro(A){(0,oo.untracked)(()=>{xi(A)})}function xi({self:A,message:t,launch:e,onLaunched:n}){A.launchController?.abort();let r=new AbortController,{signal:o}=r;A.setLaunchController(r);let i=c=>{o.aborted||c()},s={signal:o,act:i,onProgress:c=>{i(()=>{A.setProgress(c)})},onRid:c=>{i(()=>{A.setRid(c)})}};(async()=>{try{i(()=>{A.setProgress(t),A.setError(void 0)});let{warnings:c=[],...a}=await e(s);i(()=>{A.setData(a);for(let g of c)A.addWarning(g);n()}),a.tree||i(()=>{Mi(A)})}catch(c){F(c)||(i(()=>{A.setError(c)}),console.error(c))}finally{i(()=>{A.setProgress(""),A.launchController===r&&A.setLaunchController(void 0)})}})()}function Ri(A){let t=A;return t.type==="ProteinView"&&Array.isArray(t.structures)}function io(A){return A.filter(Ri)}function ao(A){let t=A.strand,e=A.refName;if(t!==-1&&t!==1)throw new Error(`Invalid strand value: ${t}. Expected 1 or -1.`);if(!e)throw new Error("refName is required");let n=new Map;for(let c of A.subfeatures??[])if(c.type==="CDS"&&c.start<c.end){let a=`${c.start}-${c.end}`;n.has(a)||n.set(a,c)}let r=[...n.values()].sort((c,a)=>t*(c.start-a.start)),o={},i={},s={};if(r.length!==0){let a=(3-(r[0]?.phase??0))%3,g=-1;for(let C of r){let Q=C.end-C.start;for(let I=0;I<Q;I++){let d=t===1?C.start+I:C.end-1-I,h=Math.floor(a++/3);o[d]=h,h!==g?(i[h]=d,s[h]=[d],g=h):s[h].push(d)}}}return{g2p:o,p2g:i,p2gCodon:s,refName:e,strand:t}}function so(A,t){let e=A[t];if(e===void 0)return;let n=[...e].sort((o,i)=>o-i),r=[];for(let o of n){let i=r.at(-1);i?.[1]===o?i[1]=o+1:r.push([o,o+1])}return r}var Fi=1e6;function ve(A){return typeof A=="object"&&A!==null}function go(A){return Number.isSafeInteger(A)}function co(A){return ve(A)&&typeof A.type=="string"&&A.type.toLowerCase()==="cds"&&go(A.start)&&go(A.end)&&A.start<A.end}function Gi(A){let t=Number(A);return t===1||t===2?t:0}function Ji(A){let{subfeatures:t}=A,e=(Array.isArray(t)?t:[]).filter(co);return e.length>0?e:co(A)?[A]:[]}function vi(A){if(!ve(A))return{reason:"it is not a feature"};let{refName:t,strand:e}=A;if(typeof t!="string"||!t)return{reason:"it has no refName"};if(e!==1&&e!==-1)return{reason:`its strand is ${JSON.stringify(e)}, not 1 or -1`};let n=Ji(A).map(o=>({refName:t,type:"CDS",start:o.start,end:o.end,phase:Gi(o.phase)}));if(n.length===0)return{reason:"it has no CDS with numeric start < end"};let r=n.reduce((o,i)=>o+i.end-i.start,0);return r>Fi?{reason:`its CDS covers ${r} bases, more than any real transcript`}:{transcript:{refName:t,strand:e,start:Math.min(...n.map(o=>o.start)),end:Math.max(...n.map(o=>o.end)),subfeatures:n}}}var Io=new WeakSet;function Qo(A){let t=vi(A);if("reason"in t){ve(A)&&!Io.has(A)&&(Io.add(A),console.warn(`[msaview] the linked transcript is not mapped to the genome: ${t.reason}`));return}let e=ao(t.transcript);return{...e,codingPositions:Object.keys(e.g2p).map(Number).sort((n,r)=>n-r)}}function Li(A,t){let e=0,n=A.length;for(;e<n;){let r=e+n>>>1;A[r]<t?e=r+1:n=r}return e}function Bo(A,t,e){let n=new Set,{codingPositions:r,g2p:o}=A;for(let i=Li(r,t);i<r.length&&r[i]<e;i++)n.add(o[r[i]]);return n}var Ui="This view's alignment is no longer in browser storage. Stored alignments are kept for 7 days after they were last used, and are lost when site data is cleared.",Co=" Retry runs the original search again and rebuilds it.",Eo=" Relaunch it from the gene to rebuild it.",qi="This view's alignment could not be read from browser storage.",_i="Part of this view is no longer in browser storage: annotations, a tree or row metadata too large for the session. Stored documents are kept for 7 days after they were last used, and are lost when site data is cleared.";function mo(A){let{dataStoreId:t}=A;t&&(async()=>{try{A.setLoadingStoredData(!0);let e=await eo(t);if(A.dataStoreId!==t)return;(0,MA.transaction)(()=>{if(e){let{data:n}=A;e.msa&&!n.msa&&A.setMSA(e.msa),e.tree&&!n.tree&&A.setTree(e.tree),e.treeMetadata&&!n.treeMetadata&&A.setTreeMetadata(e.treeMetadata),e.gff&&!n.gff&&A.setGFF(e.gff),A.setLastStoredData(e)}else A.setDataStoreId(void 0),fo(A)?A.addWarning(_i):A.setError(new Error(Ui+(A.blastParams??A.orthologParams?Co:Eo)))})}catch(e){console.error("Failed to load MSA data from IndexedDB:",e),(0,xA.isAlive)(A)&&!fo(A)&&A.setError(new Error(`${qi} ${e}.${A.blastParams??A.orthologParams?Co:Eo}`))}finally{A.setLoadingStoredData(!1)}})()}function fo(A){return!!(A.data.msa||A.msaFilehandle||A.init?.msaIndexedLocation)}function Yi(A){return!(A.msa||A.tree||A.treeMetadata||A.gff)}function Hi(A,t){return!!A&&A.msa===t.msa&&A.tree===t.tree&&A.treeMetadata===t.treeMetadata&&A.gff===t.gff}function ho(A){let{dataStoreId:t,ownsDataStoreRow:e,isStoringData:n,loadingStoredData:r,lastStoredData:o}=A,i=A.unsavedDocuments;if(!(n||r||Hi(o,i))){if(Yi(i)){o&&(0,MA.transaction)(()=>{A.setDataStoreId(void 0),A.setOwnsDataStoreRow(!1),A.setLastStoredData(i)});return}A.setIsStoringData(!0),(async()=>{try{let s=t&&e?t:$n();await Ao(s,i)&&(0,MA.transaction)(()=>{A.setDataStoreId(s),A.setOwnsDataStoreRow(!0)})}catch(s){console.error("Failed to store MSA data to IndexedDB:",s)}finally{(0,MA.transaction)(()=>{A.setLastStoredData(i),A.setIsStoringData(!1)})}})()}}function Pi(A){return!!A.connectedTranscript&&!A.connectedFeature}function wo(A,t,e,n){t&&!A.launchCompleted&&!Pi(A)&&ro({self:A,message:e,launch:n,onLaunched:()=>{A.setLaunchCompleted(!0)}})}function po(A){wo(A,!!A.orthologParams,"Resolving orthologs",t=>Mt({self:A,scope:t}))}function Do(A){wo(A,!!A.blastParams,"Submitting query",t=>yt({self:A,scope:t}))}function yo(A){let{rows:t,domainsRequested:e,annotations:n,rowData:r}=A;if(t.length>0&&n.length===0&&!e&&Object.values(r).some(o=>o?.Accession)){let o=new AbortController,i=()=>{o.abort()};(0,xA.addDisposer)(A,i),A.setDomainsRequested(!0),A.setStatus({msg:"Fetching protein domains from NCBI",onCancel:i}),(async()=>{try{await zn(A,o.signal)}catch(s){F(s)||console.error("[msaview-domains] auto-load failed:",s)}finally{(0,xA.isAlive)(A)&&A.setStatus(void 0)}})()}}function No(A){let{init:t}=A;if(t){let{msaUrl:e,msaIndexedLocation:n,msaName:r,querySeqName:o}=t,i=!!(n&&r);if(i&&A.data.msa)return;(async()=>{try{A.setError(void 0);let s=e?Pe(e):void 0;s&&A.setUniprotId(s);let c=o??(s?"query":void 0);if(c&&A.setQuerySeqName(c),e)A.setMSAFilehandle({uri:e,locationType:"UriLocation"});else if(n&&r){let a=await Kn({location:n,name:r});if(!a)throw new Error(`No alignment named ${r} in ${n.uri}`);A.setMSA(a)}i||A.setInit(void 0)}catch(s){A.setError(s),console.error(s)}})()}}function ko(A){let t=!1;return()=>{let e=On({model:A});e!==void 0?(A.setMousePos(e),t=!0):t&&(A.setMousePos(void 0),t=!1)}}function uo(A,t){let{connectedViewId:e,transcriptToMsaMap:n}=A;if(!n||!oA(A))return[];let r=new Set;for(let o of io((0,lo.getSession)(A).views))for(let i of o.structures)if(i.connectedViewId===e)for(let{start:s,end:c}of i[t]??[])for(let a of Bo(n,s,c)){let g=GA(A,a);g!==void 0&&r.add(g)}return[...r]}function Ki(A,t){return!A||!t?A===t:A.length===t.length&&A.every((e,n)=>e===t[n])}function bo(A){let t;return()=>{let{connectedViewId:e,transcriptToMsaMap:n}=A;if(!e||!n)return;let r=uo(A,"hoverGenomeHighlights"),o=r.length?[]:uo(A,"clickGenomeHighlights"),i=A.highlightColumns??[],s=r.length?r:o.length?o:i,c=s.length>0?s:void 0;Ki(t,c)||(t=c,A.setHighlightedColumns(c))}}function So(){to().catch(A=>{console.error("Failed to cleanup old MSA data:",A)})}function Mo(A){A.domainsOnGenome&&A.connectedView&&A.connectedDomains.features.length>0&&(A.showDomainsOnGenome(),A.setDomainsOnGenome(!1))}function Le(A,t){let{transcriptToMsaMap:e,mafRegion:n}=A;if(n){let r=n.start+t;return r<n.end?[{refName:n.refName,start:r,end:r+1}]:[]}if(e){let{refName:r,p2gCodon:o}=e,i=t+(A.querySeqOffset??0);return so(o,i)?.map(([s,c])=>({refName:r,start:s,end:c}))??[]}return[]}function Ae({model:A,coord:t}){let e=A.visibleColToSeqPos(A.querySeqName,t);return e===void 0?[]:Le(A,e)}function xo(A){let t=Ae(A),e=t[0],n=t.at(-1);return e&&n?{refName:e.refName,start:e.start,end:n.end}:void 0}function Ti(A){return ot(A)?"site":"domain"}function Oi(A){let t=[];for(let e of A.toSorted((n,r)=>n.start-r.start)){let n=t.at(-1);n&&n.refName===e.refName&&e.start<=n.end?n.end=Math.max(n.end,e.end):t.push({...e})}return t}function Zi(A,t){let e=[];for(let n of t)e.push(...Le(A,n));return Oi(e)}function Ro(A){let t=new Map;if(A.showDomains)for(let n of A.annotationsByRow[A.querySeqName]??[]){let r=t.get(n.accession);r?r.push(n):t.set(n.accession,[n])}let e=[...t].flatMap(([n,r])=>{let o=new Set;for(let{start:a,end:g}of r)for(let C=a-1;C<g;C++)o.add(C);let i=r[0],s=A.featureColors.get(i)?.fill,c=Zi(A,o);return s&&c.length>0?[{feature:{name:A.annotationTypes.get(n)?.name??i.name,accession:n,kind:Ti(i.featureType),regions:c},fill:s,residues:o.size}]:[]}).toSorted((n,r)=>r.residues-n.residues);return{features:e.map(n=>n.feature),color:{field:"accession",scale:{domain:e.map(n=>n.feature.accession),range:e.map(n=>n.fill),names:e.map(n=>n.feature.name)}}}}function Xi(A){return`msaview-domains-${A}`}function Fo({viewId:A,assemblyName:t,name:e,strand:n,domains:r}){let o=Xi(A),i=n===void 0?{}:{strand:n};return{type:"FeatureTrack",trackId:o,name:e,assemblyNames:[t],adapter:{type:"FromConfigAdapter",features:r.features.map(({name:s,accession:c,regions:a},g)=>{let C=`${o}-${g}`;return{uniqueId:C,refName:a[0].refName,start:Math.min(...a.map(Q=>Q.start)),end:Math.max(...a.map(Q=>Q.end)),...i,type:"protein_domain",name:s,accession:c,subfeatures:a.map((Q,I)=>({uniqueId:`${C}-${I}`,refName:Q.refName,start:Q.start,end:Q.end,...i,type:"protein_domain_part"}))}})},displays:[{type:"LinearBasicDisplay",displayId:`${o}-LinearBasicDisplay`,encoding:{color:{...r.color,legend:{title:"Domains"}}}}]}}var vo=R(To()),qe=R(nA()),Lo=R(Zo()),Uo=R(ne()),ee=R(LA());function Go(A){return A.replace(/\.\d+$/,"")}function Vi(A,t){let e=Go(t);return[A.get("name"),A.get("id"),A.get("transcript_id"),A.id()].some(n=>typeof n=="string"&&(n===t||Go(n)===e))}function Jo(A){return A.map(t=>({assemblyName:t.assemblyName,refName:t.refName,start:Math.floor(t.start),end:Math.ceil(t.end)}))}function ji(A){let t=Jo(A.dynamicBlocks?.contentBlocks??[]),e=Jo(A.displayedRegions);return t.length>0?[t,e]:[e]}function qo(A){return A.filter(t=>t.type==="FeatureTrack")}async function Wi(A,t){let e=A.connectedView,n=(0,qe.getSession)(A),r="msaview-connectedTranscript",o=qo(e.tracks);for(let i of ji(e))for(let s of o){let c=await n.rpcManager.call(r,"CoreGetFeatures",{adapterConfig:(0,vo.getConf)(s,"adapter"),regions:i});for(let a of c){let g=Ze(a).find(C=>Vi(C,t));if(g)return g}}}async function zi(A,t){let e=await Xe({start:t.get("start"),end:t.get("end"),refName:t.get("refName"),assemblyName:A.connectedView.assemblyNames[0],session:(0,qe.getSession)(A)});return(0,Lo.translateTranscript)({transcript:t,...e})?.protein}var Ue=new WeakMap;async function $i({self:A,transcriptId:t,blastParams:e,orthologParams:n,isCurrent:r}){let o=qo(A.connectedView.tracks).length;try{A.setProgress(`Looking up ${t} in the genome view...`);let i=await Wi(A,t);if(!i)throw new Error(`Transcript "${t}" was not found in the ${o} feature track(s) open in the connected genome view. Open the gene track that carries it, and make sure the view is on its locus.`);let s=await zi(A,i);if(!s)throw new Error(`Transcript "${t}" has no CDS to translate`);if(!r())return;let c=i.toJSON();(0,ee.transaction)(()=>{A.setProgress(""),e&&!e.proteinSequence&&A.setBlastParams({...e,selectedTranscript:c,proteinSequence:s}),n&&!n.proteinSequence&&A.setOrthologParams({...n,selectedTranscript:c,proteinSequence:s}),A.setConnectedFeature(c)})}catch(i){console.error(i),r()&&(A.setProgress(""),A.setError(i))}}function _o(A){let{connectedTranscript:t,connectedFeature:e,connectedView:n,blastParams:r,orthologParams:o}=A;if(!t||e||!n?.initialized||n.tracks.length===0)return;let i=(Ue.get(A)??0)+1;Ue.set(A,i),(0,ee.untracked)(()=>{$i({self:A,transcriptId:t,blastParams:r,orthologParams:o,isCurrent:()=>(0,Uo.isAlive)(A)&&Ue.get(A)===i})})}var Ho=R(nA());var Yo="session-highlights";function Aa({start:A,end:t},e,n){let r=new Set;if(e.kind==="maf")for(let o=Math.max(A,e.start);o<Math.min(t,e.end);o++)r.add(o-e.start);else for(let o=A;o<t;o++){let i=e.map.g2p[o];i!==void 0&&r.add(i-n)}return[...r].filter(o=>o>=0).sort((o,i)=>o-i)}function ea({highlights:A,onGenome:t,querySeqName:e,querySeqOffset:n,sameAssembly:r,sameRefName:o,labels:i}){return A.flatMap(s=>{if(!r(s.assemblyName)||!o(s.refName))return[];let c=[];for(let a of Aa(s,t,n)){let g=c.at(-1);g?.end===a?g.end=a+1:c.push({row:e,start:a+1,end:a+1,...i&&s.label?{label:s.label}:{},...s.color?{color:s.color}:{}})}return c})}function ta(A){return!("highlightLabelsVisible"in A&&A.highlightLabelsVisible===!1)}function Po(A){return()=>{let t=(0,Ho.getSession)(A),{connectedView:e,transcriptToMsaMap:n,mafRegion:r}=A,o=r?.assemblyName??e?.assemblyNames[0],{assemblyManager:i}=t,s=o?i.get(o):void 0,c=r?{kind:"maf",...r}:n?{kind:"transcript",map:n}:void 0;if(!t.highlightsVisible||!t.highlights.length||!c||!s?.initialized||!oA(A)){A.clearHighlight(Yo);return}let a=s.getCanonicalRefName(c.kind==="maf"?c.refName:c.map.refName);A.applyHighlight(Yo,ea({highlights:t.highlights,onGenome:c,querySeqName:A.querySeqName,querySeqOffset:A.querySeqOffset,sameAssembly:g=>i.get(g)===s,sameRefName:g=>s.getCanonicalRefName(g)===a,labels:ta(t)}))}}var Sg=["ncbi","panther","uniref"];function na(){return b.types.compose(Ko.BaseViewModel,rt(),b.types.model("MsaView",{connectedViewId:b.types.maybe(b.types.string),connectedFeature:b.types.frozen(),connectedTranscript:b.types.maybe(b.types.string),blastParams:b.types.frozen(),orthologParams:b.types.frozen(),querySeqName:b.types.stripDefault(b.types.string,"QUERY"),querySeqOffset:b.types.stripDefault(b.types.number,0),uniprotId:b.types.maybe(b.types.string),zoomToBaseLevel:b.types.stripDefault(b.types.boolean,!1),init:b.types.frozen(),dataStoreId:b.types.maybe(b.types.string),launchCompleted:!1,mafRegion:b.types.frozen(),embeddedMode:!0,domainsOnGenome:b.types.stripDefault(b.types.boolean,!1)})).volatile(()=>({rid:void 0,progress:"",loadingStoredData:!1,isStoringData:!1,lastStoredData:void 0,ownsDataStoreRow:!1,launchController:void 0,domainsRequested:!1})).views(A=>({get transcriptToMsaMap(){return A.connectedFeature?Qo(A.connectedFeature):void 0},get connectedView(){let{views:t}=(0,K.getSession)(A);return t.find(e=>e.id===A.connectedViewId)}})).views(A=>({get connectedHoverHighlights(){let{mouseCol:t}=A;return t===void 0?[]:Ae({model:A,coord:t})},get connectedClickHighlights(){let{mouseClickCol:t}=A;return t===void 0?[]:Ae({model:A,coord:t})},get connectedHighlights(){return[...this.connectedHoverHighlights,...this.connectedClickHighlights]},get connectedDomains(){return Ro(A)}})).views(A=>({get hostRestoresData(){let{msaIndexedLocation:t,msaName:e}=A.init??{};return A.hostCarriesData||!!(t&&e)},get unsavedDocuments(){let{data:t,init:e}=A,n=(0,b.getSnapshot)(t),r=(o,i)=>{let s=t[o];return s&&!i&&!n[o]?s:void 0};return{msa:r("msa",A.msaFilehandle??e?.msaIndexedLocation),tree:r("tree",A.treeFilehandle),treeMetadata:r("treeMetadata",A.treeMetadataFilehandle),gff:r("gff",A.gffFilehandle)}}})).actions(A=>({setZoomToBaseLevel(t){A.zoomToBaseLevel=t},setProgress(t){A.progress=t},setRid(t){A.rid=t},setBlastParams(t){A.blastParams=t},setConnectedFeature(t){A.connectedFeature=t},setOrthologParams(t){A.orthologParams=t},setInit(t){A.init=t},setQuerySeqName(t){A.querySeqName=t},setUniprotId(t){A.uniprotId=t},setDataStoreId(t){A.dataStoreId=t},setLaunchCompleted(t){A.launchCompleted=t},setLoadingStoredData(t){A.loadingStoredData=t},setIsStoringData(t){A.isStoringData=t},setLastStoredData(t){A.lastStoredData=t},setOwnsDataStoreRow(t){A.ownsDataStoreRow=t},setLaunchController(t){A.launchController=t},cancelLaunch(){A.launchController?.abort(),A.launchController=void 0,A.blastParams=void 0,A.orthologParams=void 0,A.init=void 0,A.launchCompleted=!1,A.progress="",A.rid=void 0,A.error=void 0},retryLaunch(){A.launchController?.abort(),A.launchController=void 0,A.progress="",A.rid=void 0,A.error=void 0,A.launchCompleted=!1,A.blastParams&&(A.blastParams={...A.blastParams}),A.orthologParams&&(A.orthologParams={...A.orthologParams}),A.init&&(A.init={...A.init})},setDomainsRequested(t){A.domainsRequested=t},setDomainsOnGenome(t){A.domainsOnGenome=t},showDomainsOnGenome(){let t=(0,K.getSession)(A),{connectedView:e,connectedDomains:n,connectedFeature:r}=A,o=e?.assemblyNames[0];if(!e||!o||n.features.length===0||!(0,K.isSessionWithAddSessionTrack)(t))return;let i=r,s=[i?.gene_name,i?.gene,i?.name].find(g=>typeof g=="string"&&g!==""),c=Fo({viewId:A.id,assemblyName:o,name:`${s??A.querySeqName} domains (from the alignment)`,strand:A.mafRegion?void 0:A.transcriptToMsaMap?.strand,domains:n}),a=(0,K.isSessionWithSessionTracks)(t)?t.sessionTracks.find(g=>g.trackId===c.trackId):void 0;a&&(0,K.isSessionWithDeleteTrackConf)(t)&&t.deleteTrackConf(a),t.addSessionTrackConf(c)&&e.launchTrack(c.trackId)},handleMsaClick(t){let{connectedView:e,zoomToBaseLevel:n}=A,r=xo({model:A,coord:t});!r||!e||(n?e.navTo(r):e.centerAt(r.start,r.refName))}})).actions(A=>{let t=A.setMouseClickPos.bind(A);return{setMouseClickPos(e,n){t(e,n),e!==void 0&&A.handleMsaClick(e)}}}).actions(A=>{let t=A.reset.bind(A);return{reset(){let{displayName:e,minimized:n,zoomToBaseLevel:r}=A;t(),e!==void 0&&A.setDisplayName(e),A.setMinimized(n),A.setZoomToBaseLevel(r),A.setDomainsRequested(!1),A.setLastStoredData(void 0),A.setOwnsDataStoreRow(!1)}}}).views(A=>{let t=A.menuItems.bind(A);return{menuItems(){return[...t(),{label:"Zoom to base level on click?",type:"checkbox",checked:A.zoomToBaseLevel,onClick:()=>{A.setZoomToBaseLevel(!A.zoomToBaseLevel)}},...A.connectedView&&A.connectedDomains.features.length>0?[{label:"Show domains on the genome",onClick:()=>{A.showDomainsOnGenome()}}]:[]]}}}).actions(A=>({afterCreate(){So(),(0,b.addDisposer)(A,()=>{A.launchController?.abort()}),mo(A);for(let t of[ho,_o,Do,po,No,yo,Mo])(0,b.addDisposer)(A,(0,RA.autorun)(()=>{t(A)}));(0,b.addDisposer)(A,(0,RA.autorun)(ko(A))),(0,b.addDisposer)(A,(0,RA.autorun)(bo(A))),(0,b.addDisposer)(A,(0,RA.autorun)(Po(A)))}}))}export{na as default,Sg as orthologSources};
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