jbrowse-plugin-msaview 2.8.2 → 2.10.0

package/dist/jbrowse-plugin-msaview.umd.production.min.js

@@ -1,4 +1,4 @@
-"use strict";var JBrowsePluginMsaView=(()=>{var HF=Object.create;var Wl=Object.defineProperty;var VF=Object.getOwnPropertyDescriptor;var jF=Object.getOwnPropertyNames;var $F=Object.getPrototypeOf,WF=Object.prototype.hasOwnProperty;var m=(e,t,r)=>()=>{if(r)throw r[0];try{return e&&(t=e(e=0)),t}catch(n){throw r=[n],n}};var K=(e,t)=>()=>{try{return t||e((t={exports:{}}).exports,t),t.exports}catch(r){throw t=0,r}},Bt=(e,t)=>{for(var r in t)Wl(e,r,{get:t[r],enumerable:!0})},Vx=(e,t,r,n)=>{if(t&&typeof t=="object"||typeof t=="function")for(let o of jF(t))!WF.call(e,o)&&o!==r&&Wl(e,o,{get:()=>t[o],enumerable:!(n=VF(t,o))||n.enumerable});return e};var p=(e,t,r)=>(r=e!=null?HF($F(e)):{},Vx(t||!e||!e.__esModule?Wl(r,"default",{value:e,enumerable:!0}):r,e)),YF=e=>Vx(Wl({},"__esModule",{value:!0}),e);var $x=K((S$,jx)=>{jx.exports=JBrowseExports["@jbrowse/core/Plugin"]});var as=K((v$,Wx)=>{Wx.exports=JBrowseExports["@jbrowse/core/configuration"]});var we=K((B$,Yx)=>{Yx.exports=JBrowseExports["@jbrowse/core/util"]});var Kt=K((T$,qx)=>{qx.exports=JBrowseExports["mobx-state-tree"]});var Q=K((M$,zx)=>{zx.exports=JBrowseExports.react});function Jx(e){var t,r,n="";if(typeof e=="string"||typeof e=="number")n+=e;else if(typeof e=="object")if(Array.isArray(e)){var o=e.length;for(t=0;t<o;t++)e[t]&&(r=Jx(e[t]))&&(n&&(n+=" "),n+=r)}else for(r in e)e[r]&&(n&&(n+=" "),n+=r);return n}function qF(){for(var e,t,r=0,n="",o=arguments.length;r<o;r++)(e=arguments[r])&&(t=Jx(e))&&(n&&(n+=" "),n+=t);return n}var cs,Yl=m(()=>{cs=qF});function ql(e,t,r=void 0){let n={};for(let o in e){let i=e[o],s="",a=!0;for(let c=0;c<i.length;c+=1){let l=i[c];l&&(s+=(a===!0?"":" ")+t(l),a=!1,r&&r[l]&&(s+=" "+r[l]))}n[o]=s}return n}var Kx=m(()=>{});var Xx=m(()=>{Kx()});function Xt(e,...t){let r=new URL(`https://mui.com/production-error/?code=${e}`);return t.forEach(n=>r.searchParams.append("args[]",n)),`Minified MUI error #${e}; visit ${r} for the full message.`}var Zx=m(()=>{});var ls=m(()=>{Zx()});function us(e){if(typeof e!="string")throw new Error(Xt(7));return e.charAt(0).toUpperCase()+e.slice(1)}var eC=m(()=>{ls()});var sm=m(()=>{eC()});var $a,tC=m(()=>{sm();$a=us});function jr(e,t){let r=Array.isArray(t),n=Array.isArray(e);return ZF(t)?t:eO(e)?fs(t):r&&n?KF(e,t):r!==n?fs(t):tO(e,t)}function zF(e){let t=0,r=e.length,n=new Array(r);for(t=0;t<r;t+=1)n[t]=fs(e[t]);return n}function JF(e){let t={};for(let r in e)r==="__proto__"||r==="constructor"||r==="prototype"||(t[r]=fs(e[r]));return t}function KF(e,t){let r=e.length;for(let n=0;n<t.length;n+=1)e[r+n]=fs(t[n]);return e}function XF(e){return typeof e=="object"&&e!==null&&!(e instanceof RegExp)&&!(e instanceof Date)}function ZF(e){return typeof e!="object"||e===null}function eO(e){return typeof e!="object"||e===null||e instanceof RegExp||e instanceof Date}function fs(e){return XF(e)?Array.isArray(e)?zF(e):JF(e):e}function tO(e,t){for(let r in t)r==="__proto__"||r==="constructor"||r==="prototype"||(r in e?e[r]=jr(e[r],t[r]):e[r]=fs(t[r]));return e}var rC=m(()=>{});var zl=m(()=>{rC()});function ds(e){if(e==null)return!0;for(let t in e)return!1;return!0}var nC=m(()=>{});var am=m(()=>{nC()});var oC=K(Ce=>{"use strict";var cm=Symbol.for("react.transitional.element"),lm=Symbol.for("react.portal"),Jl=Symbol.for("react.fragment"),Kl=Symbol.for("react.strict_mode"),Xl=Symbol.for("react.profiler"),Zl=Symbol.for("react.consumer"),eu=Symbol.for("react.context"),tu=Symbol.for("react.forward_ref"),ru=Symbol.for("react.suspense"),nu=Symbol.for("react.suspense_list"),ou=Symbol.for("react.memo"),iu=Symbol.for("react.lazy"),rO=Symbol.for("react.view_transition"),nO=Symbol.for("react.client.reference");function Cr(e){if(typeof e=="object"&&e!==null){var t=e.$$typeof;switch(t){case cm:switch(e=e.type,e){case Jl:case Xl:case Kl:case ru:case nu:case rO:return e;default:switch(e=e&&e.$$typeof,e){case eu:case tu:case iu:case ou:return e;case Zl:return e;default:return t}}case lm:return t}}}Ce.ContextConsumer=Zl;Ce.ContextProvider=eu;Ce.Element=cm;Ce.ForwardRef=tu;Ce.Fragment=Jl;Ce.Lazy=iu;Ce.Memo=ou;Ce.Portal=lm;Ce.Profiler=Xl;Ce.StrictMode=Kl;Ce.Suspense=ru;Ce.SuspenseList=nu;Ce.isContextConsumer=function(e){return Cr(e)===Zl};Ce.isContextProvider=function(e){return Cr(e)===eu};Ce.isElement=function(e){return typeof e=="object"&&e!==null&&e.$$typeof===cm};Ce.isForwardRef=function(e){return Cr(e)===tu};Ce.isFragment=function(e){return Cr(e)===Jl};Ce.isLazy=function(e){return Cr(e)===iu};Ce.isMemo=function(e){return Cr(e)===ou};Ce.isPortal=function(e){return Cr(e)===lm};Ce.isProfiler=function(e){return Cr(e)===Xl};Ce.isStrictMode=function(e){return Cr(e)===Kl};Ce.isSuspense=function(e){return Cr(e)===ru};Ce.isSuspenseList=function(e){return Cr(e)===nu};Ce.isValidElementType=function(e){return typeof e=="string"||typeof e=="function"||e===Jl||e===Xl||e===Kl||e===ru||e===nu||typeof e=="object"&&e!==null&&(e.$$typeof===iu||e.$$typeof===ou||e.$$typeof===eu||e.$$typeof===Zl||e.$$typeof===tu||e.$$typeof===nO||e.getModuleId!==void 0)};Ce.typeOf=Cr});var sC=K((J$,iC)=>{"use strict";iC.exports=oC()});function $r(e){if(typeof e!="object"||e===null)return!1;let t=Object.getPrototypeOf(e);return(t===null||t===Object.prototype||Object.getPrototypeOf(t)===null)&&!(Symbol.toStringTag in e)&&!(Symbol.iterator in e)}function aC(e){if(um.isValidElement(e)||(0,fm.isValidElementType)(e)||!$r(e))return e;let t={};return Object.keys(e).forEach(r=>{t[r]=aC(e[r])}),t}function Ke(e,t,r={clone:!0}){let n=r.clone?{...e}:e;return $r(e)&&$r(t)&&Object.keys(t).forEach(o=>{um.isValidElement(t[o])||(0,fm.isValidElementType)(t[o])?n[o]=t[o]:$r(t[o])&&Object.prototype.hasOwnProperty.call(e,o)&&$r(e[o])?n[o]=Ke(e[o],t[o],r):r.clone?n[o]=$r(t[o])?aC(t[o]):t[o]:n[o]=t[o]}),n}var um,fm,dm=m(()=>{um=p(Q(),1),fm=p(sC(),1)});var Gn=m(()=>{dm();dm()});function su(e,t){if(!e.containerQueries||!oO(t))return t;let r=[];for(let o in t)o.startsWith("@container")&&r.push(o);r.sort((o,i)=>+(o.match(cC)?.[1]||0)-+(i.match(cC)?.[1]||0));let n=t;for(let o=0;o<r.length;o+=1){let i=r[o],s=n[i];delete n[i],n[i]=s}return n}function oO(e){for(let t in e)if(t.startsWith("@container"))return!0;return!1}function au(e,t){return t==="@"||t.startsWith("@")&&(e.some(r=>t.startsWith(`@${r}`))||!!t.match(/^@\d/))}function Am(e,t){let r=t.match(/^@([^/]+)?\/?(.+)?$/);if(!r)return null;let[,n,o]=r,i=Number.isNaN(+n)?n||0:+n;return e.containerQueries(o).up(i)}function cu(e){let t=(i,s)=>i.replace("@media",s?`@container ${s}`:"@container");function r(i,s){i.up=(...a)=>t(e.breakpoints.up(...a),s),i.down=(...a)=>t(e.breakpoints.down(...a),s),i.between=(...a)=>t(e.breakpoints.between(...a),s),i.only=(...a)=>t(e.breakpoints.only(...a),s),i.not=(...a)=>{let c=t(e.breakpoints.not(...a),s);return c.includes("not all and")?c.replace("not all and ","").replace("min-width:","width<").replace("max-width:","width>").replace("and","or"):c}}let n={},o=i=>(r(n,i),n);return r(o),{...e,containerQueries:o}}var cC,mm=m(()=>{cC=/min-width:\s*([0-9.]+)/});var lu=m(()=>{mm();mm()});function Wa(e){let{values:t={xs:0,sm:600,md:900,lg:1200,xl:1536},unit:r="px",step:n=5,...o}=e,i=iO(t),s=Object.keys(i);function a(f){return`@media (min-width:${typeof t[f]=="number"?t[f]:f}${r})`}function c(f){return`@media (max-width:${(typeof t[f]=="number"?t[f]:f)-n/100}${r})`}function l(f,g){let h=s.indexOf(g);return`@media (min-width:${typeof t[f]=="number"?t[f]:f}${r}) and (max-width:${(h!==-1&&typeof t[s[h]]=="number"?t[s[h]]:g)-n/100}${r})`}function u(f){return s.indexOf(f)+1<s.length?l(f,s[s.indexOf(f)+1]):a(f)}function d(f){let g=s.indexOf(f);return g===0?a(s[1]):g===s.length-1?c(s[g]):l(f,s[s.indexOf(f)+1]).replace("@media","@media not all and")}let A=[];for(let f=0;f<s.length;f+=1)A.push(a(s[f]));return{keys:s,values:i,up:a,down:c,between:l,only:u,not:d,unit:r,internal_mediaKeys:A,...o}}var iO,pm=m(()=>{iO=e=>{let t=Object.keys(e).map(r=>({key:r,val:e[r]}))||[];return t.sort((r,n)=>r.val-n.val),t.reduce((r,n)=>({...r,[n.key]:n.val}),{})}});function mn(e,t,r){let n={};return As(n,e.theme,t,(o,i,s)=>{let a=r(i,s);o?n[o]=a:jr(n,a)})}function As(e,t,r,n){if(t??=sO,Array.isArray(r)){let o=t.breakpoints??Ya;for(let i=0;i<r.length;i+=1)gm(e,o.up(o.keys[i]),r[i],void 0,n);return e}if(typeof r=="object"){let o=t.breakpoints??Ya,i=o.values??qa;for(let s in r)if(au(o.keys,s)){let a=Am(t.containerQueries?t:aO,s);a&&gm(e,a,r[s],s,n)}else if(s in i){let a=o.up(s);gm(e,a,r[s],s,n)}else{let a=s;e[a]=r[a]}return e}return n(void 0,r),e}function gm(e,t,r,n,o){e[t]??={},o(t,r,n)}function lC(e=Ya){let{internal_mediaKeys:t}=e,r={};for(let n=0;n<t.length;n+=1)r[t[n]]={};return r}function hm(e,t){let r=e.internal_mediaKeys;for(let n=0;n<r.length;n+=1){let o=r[n];ds(t[o])&&delete t[o]}return t}function uC(e,t){if(Array.isArray(t))return!0;if(typeof t=="object"&&t!==null){for(let n=0;n<e.keys.length;n+=1)if(e.keys[n]in t)return!0;let r=Object.keys(t);for(let n=0;n<r.length;n+=1)if(au(e.keys,r[n]))return!0}return!1}var sO,qa,Ya,aO,fC=m(()=>{am();zl();lu();pm();sO={},qa={xs:0,sm:600,md:900,lg:1200,xl:1536},Ya=Wa({values:qa}),aO={containerQueries:e=>({up:t=>{let r=typeof t=="number"?t:qa[t]||t;return typeof r=="number"&&(r=`${r}px`),e?`@container ${e} (min-width:${r})`:`@container (min-width:${r})`}})}});var Ao=m(()=>{fC()});function ym(e,t,r,n){let o;return typeof e=="function"?o=e(r):Array.isArray(e)?o=e[r]||r:typeof r=="string"?o=ms(e,r,!0,n)||r:o=r,t&&(o=t(o,r,e)),o}function ms(e,t,r=!0,n=void 0){if(!e||!t)return null;let o=t.split(".");if(e.vars&&r){let i=dC(e.vars,o,n);if(i!=null)return i}return dC(e,o,n)}function dC(e,t,r=void 0){let n,o=e,i=0;for(;i<t.length;){if(o==null)return o;n=o,o=o[t[i]],i+=1}if(r&&o===void 0){let s=t[t.length-1],a=`${r}${s==="default"?"":us(s)}`;return n?.[a]}return o}function $(e){let{prop:t,cssProperty:r=e.prop,themeKey:n,transform:o}=e,i=s=>{if(s[t]==null)return null;let a=s[t],c=s.theme,l=ms(c,n)||{};return mn(s,a,d=>{let A=ym(l,o,d,t);return r===!1?A:{[r]:A}})};return i.propTypes={},i.filterProps=[t],i}var xm=m(()=>{sm();Ao()});var pn=m(()=>{xm();xm()});function Jo(e,t,r,n){let o=ms(e,t,!0)??r;return typeof o=="number"||typeof o=="string"?i=>typeof i=="string"?i:typeof o=="string"?o.startsWith("var(")&&i===0?0:o.startsWith("var(")&&i===1?o:`calc(${i} * ${o})`:o*i:Array.isArray(o)?i=>{if(typeof i=="string")return i;let s=Math.abs(i),a=o[s];return i>=0?a:typeof a=="number"?-a:typeof a=="string"&&a.startsWith("var(")?`calc(-1 * ${a})`:`-${a}`}:typeof o=="function"?o:()=>{}}function Ja(e){return Jo(e,"spacing",8,"spacing")}function Ko(e,t){return typeof t=="string"||t==null?t:e(t)}function Em(e,t){let r=e.theme??lO,n=r?.internal_cache?.unarySpacing??Ja(r),o={};for(let i in e){if(!t.has(i))continue;let s=za[i]??(pC[0]=i,pC),a=e[i];As(o,e.theme,a,(c,l)=>{let u=c?o[c]:o;for(let d=0;d<s.length;d+=1)u[s[d]]=Ko(n,l)})}return o}function wm(e){return Em(e,Cm)}function Im(e){return Em(e,bm)}function hC(e){return Em(e,gC)}var lO,uu,AC,mC,za,Cm,bm,gC,pC,We,Ye,yC=m(()=>{Ao();pn();lO={internal_cache:{}},uu={m:"margin",p:"padding"},AC={t:"Top",r:"Right",b:"Bottom",l:"Left",x:["Left","Right"],y:["Top","Bottom"]},mC={marginX:"mx",marginY:"my",paddingX:"px",paddingY:"py"},za={};for(let e in uu)za[e]=[uu[e]];for(let e in uu)for(let t in AC){let r=uu[e],n=AC[t],o=Array.isArray(n)?n.map(i=>r+i):[r+n];za[e+t]=o}for(let e in mC)za[e]=za[mC[e]];Cm=new Set(["m","mt","mr","mb","ml","mx","my","margin","marginTop","marginRight","marginBottom","marginLeft","marginX","marginY","marginInline","marginInlineStart","marginInlineEnd","marginBlock","marginBlockStart","marginBlockEnd"]),bm=new Set(["p","pt","pr","pb","pl","px","py","padding","paddingTop","paddingRight","paddingBottom","paddingLeft","paddingX","paddingY","paddingInline","paddingInlineStart","paddingInlineEnd","paddingBlock","paddingBlockStart","paddingBlockEnd"]),gC=new Set([...Cm,...bm]);pC=[""];wm.propTypes={};wm.filterProps=Cm;We=wm;Im.propTypes={};Im.filterProps=bm;Ye=Im;hC.propTypes={};hC.filterProps=gC});var Xo=m(()=>{yC()});function uO(...e){let t=e.reduce((n,o)=>(o.filterProps.forEach(i=>{n[i]=o}),n),{}),r=n=>{let o={};for(let i in n)t[i]&&jr(o,t[i](n));return o};return r.propTypes={},r.filterProps=e.reduce((n,o)=>n.concat(o.filterProps),[]),r}var Ot,xC=m(()=>{zl();Ot=uO});var mo=m(()=>{xC()});function or(e){return typeof e!="number"?e:`${e}px solid`}function br(e,t){return $({prop:e,themeKey:"borders",transform:t})}var fO,dO,AO,mO,pO,gO,hO,yO,xO,CO,bO,EO,Ka,QW,CC=m(()=>{pn();mo();Xo();Ao();fO=br("border",or),dO=br("borderTop",or),AO=br("borderRight",or),mO=br("borderBottom",or),pO=br("borderLeft",or),gO=br("borderColor"),hO=br("borderTopColor"),yO=br("borderRightColor"),xO=br("borderBottomColor"),CO=br("borderLeftColor"),bO=br("outline",or),EO=br("outlineColor"),Ka=e=>{if(e.borderRadius!==void 0&&e.borderRadius!==null){let t=Jo(e.theme,"shape.borderRadius",4,"borderRadius"),r=n=>({borderRadius:Ko(t,n)});return mn(e,e.borderRadius,r)}return null};Ka.propTypes={};Ka.filterProps=["borderRadius"];QW=Ot(fO,dO,AO,mO,pO,gO,hO,yO,xO,CO,Ka,bO,EO)});var Sm=m(()=>{CC()});var Xa,Za,ec,wO,IO,SO,vO,BO,TO,MO,RO,QO,OW,bC=m(()=>{pn();mo();Xo();Ao();Xa=e=>{if(e.gap!==void 0&&e.gap!==null){let t=Jo(e.theme,"spacing",8,"gap"),r=n=>({gap:Ko(t,n)});return mn(e,e.gap,r)}return null};Xa.propTypes={};Xa.filterProps=["gap"];Za=e=>{if(e.columnGap!==void 0&&e.columnGap!==null){let t=Jo(e.theme,"spacing",8,"columnGap"),r=n=>({columnGap:Ko(t,n)});return mn(e,e.columnGap,r)}return null};Za.propTypes={};Za.filterProps=["columnGap"];ec=e=>{if(e.rowGap!==void 0&&e.rowGap!==null){let t=Jo(e.theme,"spacing",8,"rowGap"),r=n=>({rowGap:Ko(t,n)});return mn(e,e.rowGap,r)}return null};ec.propTypes={};ec.filterProps=["rowGap"];wO=$({prop:"gridColumn"}),IO=$({prop:"gridRow"}),SO=$({prop:"gridAutoFlow"}),vO=$({prop:"gridAutoColumns"}),BO=$({prop:"gridAutoRows"}),TO=$({prop:"gridTemplateColumns"}),MO=$({prop:"gridTemplateRows"}),RO=$({prop:"gridTemplateAreas"}),QO=$({prop:"gridArea"}),OW=Ot(Xa,Za,ec,wO,IO,SO,vO,BO,TO,MO,RO,QO)});var vm=m(()=>{bC()});function Zo(e,t){return t==="grey"?t:e}var _O,kO,DO,$W,EC=m(()=>{pn();mo();_O=$({prop:"color",themeKey:"palette",transform:Zo}),kO=$({prop:"bgcolor",cssProperty:"backgroundColor",themeKey:"palette",transform:Zo}),DO=$({prop:"backgroundColor",themeKey:"palette",transform:Zo}),$W=Ot(_O,kO,DO)});var Bm=m(()=>{EC()});function Zt(e){return e<=1&&e!==0?`${e*100}%`:e}var NO,LO,fu,PO,FO,OO,GO,XW,ZW,UO,eY,wC=m(()=>{pn();mo();Ao();Ao();NO=qa;LO=$({prop:"width",transform:Zt}),fu=e=>{if(e.maxWidth!==void 0&&e.maxWidth!==null){let t=r=>{let n=e.theme?.breakpoints?.values?.[r]||NO[r];return n?e.theme?.breakpoints?.unit!=="px"?{maxWidth:`${n}${e.theme.breakpoints.unit}`}:{maxWidth:n}:{maxWidth:Zt(r)}};return mn(e,e.maxWidth,t)}return null};fu.filterProps=["maxWidth"];PO=$({prop:"minWidth",transform:Zt}),FO=$({prop:"height",transform:Zt}),OO=$({prop:"maxHeight",transform:Zt}),GO=$({prop:"minHeight",transform:Zt}),XW=$({prop:"size",cssProperty:"width",transform:Zt}),ZW=$({prop:"size",cssProperty:"height",transform:Zt}),UO=$({prop:"boxSizing"}),eY=Ot(LO,fu,PO,FO,OO,GO,UO)});var Tm=m(()=>{wC()});var HO,Un,du=m(()=>{Xo();Sm();vm();Bm();Tm();HO={border:{themeKey:"borders",transform:or},borderTop:{themeKey:"borders",transform:or},borderRight:{themeKey:"borders",transform:or},borderBottom:{themeKey:"borders",transform:or},borderLeft:{themeKey:"borders",transform:or},borderColor:{themeKey:"palette"},borderTopColor:{themeKey:"palette"},borderRightColor:{themeKey:"palette"},borderBottomColor:{themeKey:"palette"},borderLeftColor:{themeKey:"palette"},outline:{themeKey:"borders",transform:or},outlineColor:{themeKey:"palette"},borderRadius:{themeKey:"shape.borderRadius",style:Ka},color:{themeKey:"palette",transform:Zo},bgcolor:{themeKey:"palette",cssProperty:"backgroundColor",transform:Zo},backgroundColor:{themeKey:"palette",transform:Zo},p:{style:Ye},pt:{style:Ye},pr:{style:Ye},pb:{style:Ye},pl:{style:Ye},px:{style:Ye},py:{style:Ye},padding:{style:Ye},paddingTop:{style:Ye},paddingRight:{style:Ye},paddingBottom:{style:Ye},paddingLeft:{style:Ye},paddingX:{style:Ye},paddingY:{style:Ye},paddingInline:{style:Ye},paddingInlineStart:{style:Ye},paddingInlineEnd:{style:Ye},paddingBlock:{style:Ye},paddingBlockStart:{style:Ye},paddingBlockEnd:{style:Ye},m:{style:We},mt:{style:We},mr:{style:We},mb:{style:We},ml:{style:We},mx:{style:We},my:{style:We},margin:{style:We},marginTop:{style:We},marginRight:{style:We},marginBottom:{style:We},marginLeft:{style:We},marginX:{style:We},marginY:{style:We},marginInline:{style:We},marginInlineStart:{style:We},marginInlineEnd:{style:We},marginBlock:{style:We},marginBlockStart:{style:We},marginBlockEnd:{style:We},displayPrint:{cssProperty:!1,transform:e=>({"@media print":{display:e}})},display:{},overflow:{},textOverflow:{},visibility:{},whiteSpace:{},flexBasis:{},flexDirection:{},flexWrap:{},justifyContent:{},alignItems:{},alignContent:{},order:{},flex:{},flexGrow:{},flexShrink:{},alignSelf:{},justifyItems:{},justifySelf:{},gap:{style:Xa},rowGap:{style:ec},columnGap:{style:Za},gridColumn:{},gridRow:{},gridAutoFlow:{},gridAutoColumns:{},gridAutoRows:{},gridTemplateColumns:{},gridTemplateRows:{},gridTemplateAreas:{},gridArea:{},position:{},zIndex:{themeKey:"zIndex"},top:{},right:{},bottom:{},left:{},boxShadow:{themeKey:"shadows"},width:{transform:Zt},maxWidth:{style:fu},minWidth:{transform:Zt},height:{transform:Zt},maxHeight:{transform:Zt},minHeight:{transform:Zt},boxSizing:{},font:{themeKey:"font"},fontFamily:{themeKey:"typography"},fontSize:{themeKey:"typography"},fontStyle:{themeKey:"typography"},fontWeight:{themeKey:"typography"},letterSpacing:{},textTransform:{},lineHeight:{},textAlign:{},typography:{cssProperty:!1,themeKey:"typography"}},Un=HO});function jO(){function e(t){if(!t.sx)return null;let{sx:r,theme:n=VO,nested:o}=t,i=n.unstable_sxConfig??Un,s={sx:null,theme:n,nested:!0};function a(c){let l=c;if(typeof c=="function")l=c(n);else if(typeof c!="object")return c;if(!l)return null;let u=n.breakpoints??Ya,d=lC(u);for(let A in l){let f=$O(l[A],n);if(f!=null){if(typeof f!="object"){IC(d,A,f,n,i);continue}if(i[A]){IC(d,A,f,n,i);continue}uC(u,f)?As(d,t.theme,f,(g,h)=>{d[g][A]=h}):(s.sx=f,d[A]=e(s))}}return!o&&n.modularCssLayers?{"@layer sx":su(n,hm(u,d))}:su(n,hm(u,d))}return Array.isArray(r)?r.map(a):a(r)}return e.filterProps=["sx"],e}function IC(e,t,r,n,o){let i=o[t];if(!i){e[t]=r;return}if(r==null)return;let{themeKey:s}=i;if(s==="typography"&&r==="inherit"){e[t]=r;return}let{style:a}=i;if(a){jr(e,a({[t]:r,theme:n}));return}let{cssProperty:c=t,transform:l}=i,u=ms(n,s);As(e,n,r,(d,A)=>{let f=ym(u,l,A,t);c===!1?d?jr(e[d],f):jr(e,f):d?e[d][c]=f:e[c]=f})}function $O(e,t){return typeof e=="function"?e(t):e}var VO,Er,Mm=m(()=>{zl();pn();Ao();lu();du();VO={};Er=jO()});var tc=m(()=>{Mm();du()});function rc(){return rc=Object.assign?Object.assign.bind():function(e){for(var t=1;t<arguments.length;t++){var r=arguments[t];for(var n in r)({}).hasOwnProperty.call(r,n)&&(e[n]=r[n])}return e},rc.apply(null,arguments)}var nc=m(()=>{});function YO(e){if(e.sheet)return e.sheet;for(var t=0;t<document.styleSheets.length;t++)if(document.styleSheets[t].ownerNode===e)return document.styleSheets[t]}function qO(e){var t=document.createElement("style");return t.setAttribute("data-emotion",e.key),e.nonce!==void 0&&t.setAttribute("nonce",e.nonce),t.appendChild(document.createTextNode("")),t.setAttribute("data-s",""),t}var WO,SC,vC=m(()=>{WO=!1;SC=(function(){function e(r){var n=this;this._insertTag=function(o){var i;n.tags.length===0?n.insertionPoint?i=n.insertionPoint.nextSibling:n.prepend?i=n.container.firstChild:i=n.before:i=n.tags[n.tags.length-1].nextSibling,n.container.insertBefore(o,i),n.tags.push(o)},this.isSpeedy=r.speedy===void 0?!WO:r.speedy,this.tags=[],this.ctr=0,this.nonce=r.nonce,this.key=r.key,this.container=r.container,this.prepend=r.prepend,this.insertionPoint=r.insertionPoint,this.before=null}var t=e.prototype;return t.hydrate=function(n){n.forEach(this._insertTag)},t.insert=function(n){this.ctr%(this.isSpeedy?65e3:1)===0&&this._insertTag(qO(this));var o=this.tags[this.tags.length-1];if(this.isSpeedy){var i=YO(o);try{i.insertRule(n,i.cssRules.length)}catch{}}else o.appendChild(document.createTextNode(n));this.ctr++},t.flush=function(){this.tags.forEach(function(n){var o;return(o=n.parentNode)==null?void 0:o.removeChild(n)}),this.tags=[],this.ctr=0},e})()});var yt,oc,se,Au,ps,gs,BC,mu,TC,pu=m(()=>{yt="-ms-",oc="-moz-",se="-webkit-",Au="comm",ps="rule",gs="decl",BC="@import",mu="@keyframes",TC="@layer"});function QC(e,t){return qe(e,0)^45?(((t<<2^qe(e,0))<<2^qe(e,1))<<2^qe(e,2))<<2^qe(e,3):0}function gu(e){return e.trim()}function Rm(e,t){return(e=t.exec(e))?e[0]:e}function re(e,t,r){return e.replace(t,r)}function ic(e,t){return e.indexOf(t)}function qe(e,t){return e.charCodeAt(t)|0}function po(e,t,r){return e.slice(t,r)}function Gt(e){return e.length}function hs(e){return e.length}function ys(e,t){return t.push(e),e}function Qm(e,t){return e.map(t).join("")}var MC,ei,RC,xs=m(()=>{MC=Math.abs,ei=String.fromCharCode,RC=Object.assign});function sc(e,t,r,n,o,i,s){return{value:e,root:t,parent:r,type:n,props:o,children:i,line:hu,column:Cs,length:s,return:""}}function ws(e,t){return RC(sc("",null,null,"",null,null,0),e,{length:-e.length},t)}function kC(){return Xe}function DC(){return Xe=Ut>0?qe(Es,--Ut):0,Cs--,Xe===10&&(Cs=1,hu--),Xe}function Ht(){return Xe=Ut<_C?qe(Es,Ut++):0,Cs++,Xe===10&&(Cs=1,hu++),Xe}function wr(){return qe(Es,Ut)}function ac(){return Ut}function Is(e,t){return po(Es,e,t)}function bs(e){switch(e){case 0:case 9:case 10:case 13:case 32:return 5;case 33:case 43:case 44:case 47:case 62:case 64:case 126:case 59:case 123:case 125:return 4;case 58:return 3;case 34:case 39:case 40:case 91:return 2;case 41:case 93:return 1}return 0}function yu(e){return hu=Cs=1,_C=Gt(Es=e),Ut=0,[]}function xu(e){return Es="",e}function Ss(e){return gu(Is(Ut-1,_m(e===91?e+2:e===40?e+1:e)))}function NC(e){for(;(Xe=wr())&&Xe<33;)Ht();return bs(e)>2||bs(Xe)>3?"":" "}function LC(e,t){for(;--t&&Ht()&&!(Xe<48||Xe>102||Xe>57&&Xe<65||Xe>70&&Xe<97););return Is(e,ac()+(t<6&&wr()==32&&Ht()==32))}function _m(e){for(;Ht();)switch(Xe){case e:return Ut;case 34:case 39:e!==34&&e!==39&&_m(Xe);break;case 40:e===41&&_m(e);break;case 92:Ht();break}return Ut}function PC(e,t){for(;Ht()&&e+Xe!==57;)if(e+Xe===84&&wr()===47)break;return"/*"+Is(t,Ut-1)+"*"+ei(e===47?e:Ht())}function FC(e){for(;!bs(wr());)Ht();return Is(e,Ut)}var hu,Cs,_C,Ut,Xe,Es,km=m(()=>{xs();hu=1,Cs=1,_C=0,Ut=0,Xe=0,Es=""});function UC(e){return xu(Cu("",null,null,null,[""],e=yu(e),0,[0],e))}function Cu(e,t,r,n,o,i,s,a,c){for(var l=0,u=0,d=s,A=0,f=0,g=0,h=1,y=1,E=1,x=0,S="",w=o,I=i,v=n,B=S;y;)switch(g=x,x=Ht()){case 40:if(g!=108&&qe(B,d-1)==58){ic(B+=re(Ss(x),"&","&\f"),"&\f")!=-1&&(E=-1);break}case 34:case 39:case 91:B+=Ss(x);break;case 9:case 10:case 13:case 32:B+=NC(g);break;case 92:B+=LC(ac()-1,7);continue;case 47:switch(wr()){case 42:case 47:ys(zO(PC(Ht(),ac()),t,r),c);break;default:B+="/"}break;case 123*h:a[l++]=Gt(B)*E;case 125*h:case 59:case 0:switch(x){case 0:case 125:y=0;case 59+u:E==-1&&(B=re(B,/\f/g,"")),f>0&&Gt(B)-d&&ys(f>32?GC(B+";",n,r,d-1):GC(re(B," ","")+";",n,r,d-2),c);break;case 59:B+=";";default:if(ys(v=OC(B,t,r,l,u,o,a,S,w=[],I=[],d),i),x===123)if(u===0)Cu(B,t,v,v,w,i,d,a,I);else switch(A===99&&qe(B,3)===110?100:A){case 100:case 108:case 109:case 115:Cu(e,v,v,n&&ys(OC(e,v,v,0,0,o,a,S,o,w=[],d),I),o,I,d,a,n?w:I);break;default:Cu(B,v,v,v,[""],I,0,a,I)}}l=u=f=0,h=E=1,S=B="",d=s;break;case 58:d=1+Gt(B),f=g;default:if(h<1){if(x==123)--h;else if(x==125&&h++==0&&DC()==125)continue}switch(B+=ei(x),x*h){case 38:E=u>0?1:(B+="\f",-1);break;case 44:a[l++]=(Gt(B)-1)*E,E=1;break;case 64:wr()===45&&(B+=Ss(Ht())),A=wr(),u=d=Gt(S=B+=FC(ac())),x++;break;case 45:g===45&&Gt(B)==2&&(h=0)}}return i}function OC(e,t,r,n,o,i,s,a,c,l,u){for(var d=o-1,A=o===0?i:[""],f=hs(A),g=0,h=0,y=0;g<n;++g)for(var E=0,x=po(e,d+1,d=MC(h=s[g])),S=e;E<f;++E)(S=gu(h>0?A[E]+" "+x:re(x,/&\f/g,A[E])))&&(c[y++]=S);return sc(e,t,r,o===0?ps:a,c,l,u)}function zO(e,t,r){return sc(e,t,r,Au,ei(kC()),po(e,2,-2),0)}function GC(e,t,r,n){return sc(e,t,r,gs,po(e,0,n),po(e,n+1,-1),n)}var HC=m(()=>{pu();xs();km()});var VC=m(()=>{});function ti(e,t){for(var r="",n=hs(e),o=0;o<n;o++)r+=t(e[o],o,e,t)||"";return r}function jC(e,t,r,n){switch(e.type){case TC:if(e.children.length)break;case BC:case gs:return e.return=e.return||e.value;case Au:return"";case mu:return e.return=e.value+"{"+ti(e.children,n)+"}";case ps:e.value=e.props.join(",")}return Gt(r=ti(e.children,n))?e.return=e.value+"{"+r+"}":""}var $C=m(()=>{pu();xs()});function WC(e){var t=hs(e);return function(r,n,o,i){for(var s="",a=0;a<t;a++)s+=e[a](r,n,o,i)||"";return s}}function YC(e){return function(t){t.root||(t=t.return)&&e(t)}}var qC=m(()=>{xs()});var zC=m(()=>{pu();xs();HC();VC();km();$C();qC()});var bu=m(()=>{});function Eu(e){var t=Object.create(null);return function(r){return t[r]===void 0&&(t[r]=e(r)),t[r]}}var wu=m(()=>{});function KC(e,t){switch(QC(e,t)){case 5103:return se+"print-"+e+e;case 5737:case 4201:case 3177:case 3433:case 1641:case 4457:case 2921:case 5572:case 6356:case 5844:case 3191:case 6645:case 3005:case 6391:case 5879:case 5623:case 6135:case 4599:case 4855:case 4215:case 6389:case 5109:case 5365:case 5621:case 3829:return se+e+e;case 5349:case 4246:case 4810:case 6968:case 2756:return se+e+oc+e+yt+e+e;case 6828:case 4268:return se+e+yt+e+e;case 6165:return se+e+yt+"flex-"+e+e;case 5187:return se+e+re(e,/(\w+).+(:[^]+)/,se+"box-$1$2"+yt+"flex-$1$2")+e;case 5443:return se+e+yt+"flex-item-"+re(e,/flex-|-self/,"")+e;case 4675:return se+e+yt+"flex-line-pack"+re(e,/align-content|flex-|-self/,"")+e;case 5548:return se+e+yt+re(e,"shrink","negative")+e;case 5292:return se+e+yt+re(e,"basis","preferred-size")+e;case 6060:return se+"box-"+re(e,"-grow","")+se+e+yt+re(e,"grow","positive")+e;case 4554:return se+re(e,/([^-])(transform)/g,"$1"+se+"$2")+e;case 6187:return re(re(re(e,/(zoom-|grab)/,se+"$1"),/(image-set)/,se+"$1"),e,"")+e;case 5495:case 3959:return re(e,/(image-set\([^]*)/,se+"$1$`$1");case 4968:return re(re(e,/(.+:)(flex-)?(.*)/,se+"box-pack:$3"+yt+"flex-pack:$3"),/s.+-b[^;]+/,"justify")+se+e+e;case 4095:case 3583:case 4068:case 2532:return re(e,/(.+)-inline(.+)/,se+"$1$2")+e;case 8116:case 7059:case 5753:case 5535:case 5445:case 5701:case 4933:case 4677:case 5533:case 5789:case 5021:case 4765:if(Gt(e)-1-t>6)switch(qe(e,t+1)){case 109:if(qe(e,t+4)!==45)break;case 102:return re(e,/(.+:)(.+)-([^]+)/,"$1"+se+"$2-$3$1"+oc+(qe(e,t+3)==108?"$3":"$2-$3"))+e;case 115:return~ic(e,"stretch")?KC(re(e,"stretch","fill-available"),t)+e:e}break;case 4949:if(qe(e,t+1)!==115)break;case 6444:switch(qe(e,Gt(e)-3-(~ic(e,"!important")&&10))){case 107:return re(e,":",":"+se)+e;case 101:return re(e,/(.+:)([^;!]+)(;|!.+)?/,"$1"+se+(qe(e,14)===45?"inline-":"")+"box$3$1"+se+"$2$3$1"+yt+"$2box$3")+e}break;case 5936:switch(qe(e,t+11)){case 114:return se+e+yt+re(e,/[svh]\w+-[tblr]{2}/,"tb")+e;case 108:return se+e+yt+re(e,/[svh]\w+-[tblr]{2}/,"tb-rl")+e;case 45:return se+e+yt+re(e,/[svh]\w+-[tblr]{2}/,"lr")+e}return se+e+yt+e+e}return e}var JO,KO,XO,JC,ZO,e5,t5,r5,XC,Dm=m(()=>{vC();zC();bu();wu();JO=function(t,r,n){for(var o=0,i=0;o=i,i=wr(),o===38&&i===12&&(r[n]=1),!bs(i);)Ht();return Is(t,Ut)},KO=function(t,r){var n=-1,o=44;do switch(bs(o)){case 0:o===38&&wr()===12&&(r[n]=1),t[n]+=JO(Ut-1,r,n);break;case 2:t[n]+=Ss(o);break;case 4:if(o===44){t[++n]=wr()===58?"&\f":"",r[n]=t[n].length;break}default:t[n]+=ei(o)}while(o=Ht());return t},XO=function(t,r){return xu(KO(yu(t),r))},JC=new WeakMap,ZO=function(t){if(!(t.type!=="rule"||!t.parent||t.length<1)){for(var r=t.value,n=t.parent,o=t.column===n.column&&t.line===n.line;n.type!=="rule";)if(n=n.parent,!n)return;if(!(t.props.length===1&&r.charCodeAt(0)!==58&&!JC.get(n))&&!o){JC.set(t,!0);for(var i=[],s=XO(r,i),a=n.props,c=0,l=0;c<s.length;c++)for(var u=0;u<a.length;u++,l++)t.props[l]=i[c]?s[c].replace(/&\f/g,a[u]):a[u]+" "+s[c]}}},e5=function(t){if(t.type==="decl"){var r=t.value;r.charCodeAt(0)===108&&r.charCodeAt(2)===98&&(t.return="",t.value="")}};t5=function(t,r,n,o){if(t.length>-1&&!t.return)switch(t.type){case gs:t.return=KC(t.value,t.length);break;case mu:return ti([ws(t,{value:re(t.value,"@","@"+se)})],o);case ps:if(t.length)return Qm(t.props,function(i){switch(Rm(i,/(::plac\w+|:read-\w+)/)){case":read-only":case":read-write":return ti([ws(t,{props:[re(i,/:(read-\w+)/,":"+oc+"$1")]})],o);case"::placeholder":return ti([ws(t,{props:[re(i,/:(plac\w+)/,":"+se+"input-$1")]}),ws(t,{props:[re(i,/:(plac\w+)/,":"+oc+"$1")]}),ws(t,{props:[re(i,/:(plac\w+)/,yt+"input-$1")]})],o)}return""})}},r5=[t5],XC=function(t){var r=t.key;if(r==="css"){var n=document.querySelectorAll("style[data-emotion]:not([data-s])");Array.prototype.forEach.call(n,function(h){var y=h.getAttribute("data-emotion");y.indexOf(" ")!==-1&&(document.head.appendChild(h),h.setAttribute("data-s",""))})}var o=t.stylisPlugins||r5,i={},s,a=[];s=t.container||document.head,Array.prototype.forEach.call(document.querySelectorAll('style[data-emotion^="'+r+' "]'),function(h){for(var y=h.getAttribute("data-emotion").split(" "),E=1;E<y.length;E++)i[y[E]]=!0;a.push(h)});var c,l=[ZO,e5];{var u,d=[jC,YC(function(h){u.insert(h)})],A=WC(l.concat(o,d)),f=function(y){return ti(UC(y),A)};c=function(y,E,x,S){u=x,f(y?y+"{"+E.styles+"}":E.styles),S&&(g.inserted[E.name]=!0)}}var g={key:r,sheet:new SC({key:r,container:s,nonce:t.nonce,speedy:t.speedy,prepend:t.prepend,insertionPoint:t.insertionPoint}),nonce:t.nonce,inserted:i,registered:{},insert:c};return g.sheet.hydrate(a),g}});var eb=K(me=>{"use strict";var ut=typeof Symbol=="function"&&Symbol.for,Nm=ut?Symbol.for("react.element"):60103,Lm=ut?Symbol.for("react.portal"):60106,Iu=ut?Symbol.for("react.fragment"):60107,Su=ut?Symbol.for("react.strict_mode"):60108,vu=ut?Symbol.for("react.profiler"):60114,Bu=ut?Symbol.for("react.provider"):60109,Tu=ut?Symbol.for("react.context"):60110,Pm=ut?Symbol.for("react.async_mode"):60111,Mu=ut?Symbol.for("react.concurrent_mode"):60111,Ru=ut?Symbol.for("react.forward_ref"):60112,Qu=ut?Symbol.for("react.suspense"):60113,n5=ut?Symbol.for("react.suspense_list"):60120,_u=ut?Symbol.for("react.memo"):60115,ku=ut?Symbol.for("react.lazy"):60116,o5=ut?Symbol.for("react.block"):60121,i5=ut?Symbol.for("react.fundamental"):60117,s5=ut?Symbol.for("react.responder"):60118,a5=ut?Symbol.for("react.scope"):60119;function ir(e){if(typeof e=="object"&&e!==null){var t=e.$$typeof;switch(t){case Nm:switch(e=e.type,e){case Pm:case Mu:case Iu:case vu:case Su:case Qu:return e;default:switch(e=e&&e.$$typeof,e){case Tu:case Ru:case ku:case _u:case Bu:return e;default:return t}}case Lm:return t}}}function ZC(e){return ir(e)===Mu}me.AsyncMode=Pm;me.ConcurrentMode=Mu;me.ContextConsumer=Tu;me.ContextProvider=Bu;me.Element=Nm;me.ForwardRef=Ru;me.Fragment=Iu;me.Lazy=ku;me.Memo=_u;me.Portal=Lm;me.Profiler=vu;me.StrictMode=Su;me.Suspense=Qu;me.isAsyncMode=function(e){return ZC(e)||ir(e)===Pm};me.isConcurrentMode=ZC;me.isContextConsumer=function(e){return ir(e)===Tu};me.isContextProvider=function(e){return ir(e)===Bu};me.isElement=function(e){return typeof e=="object"&&e!==null&&e.$$typeof===Nm};me.isForwardRef=function(e){return ir(e)===Ru};me.isFragment=function(e){return ir(e)===Iu};me.isLazy=function(e){return ir(e)===ku};me.isMemo=function(e){return ir(e)===_u};me.isPortal=function(e){return ir(e)===Lm};me.isProfiler=function(e){return ir(e)===vu};me.isStrictMode=function(e){return ir(e)===Su};me.isSuspense=function(e){return ir(e)===Qu};me.isValidElementType=function(e){return typeof e=="string"||typeof e=="function"||e===Iu||e===Mu||e===vu||e===Su||e===Qu||e===n5||typeof e=="object"&&e!==null&&(e.$$typeof===ku||e.$$typeof===_u||e.$$typeof===Bu||e.$$typeof===Tu||e.$$typeof===Ru||e.$$typeof===i5||e.$$typeof===s5||e.$$typeof===a5||e.$$typeof===o5)};me.typeOf=ir});var rb=K((KY,tb)=>{"use strict";tb.exports=eb()});var lb=K((XY,cb)=>{"use strict";var Fm=rb(),c5={childContextTypes:!0,contextType:!0,contextTypes:!0,defaultProps:!0,displayName:!0,getDefaultProps:!0,getDerivedStateFromError:!0,getDerivedStateFromProps:!0,mixins:!0,propTypes:!0,type:!0},l5={name:!0,length:!0,prototype:!0,caller:!0,callee:!0,arguments:!0,arity:!0},u5={$$typeof:!0,render:!0,defaultProps:!0,displayName:!0,propTypes:!0},sb={$$typeof:!0,compare:!0,defaultProps:!0,displayName:!0,propTypes:!0,type:!0},Om={};Om[Fm.ForwardRef]=u5;Om[Fm.Memo]=sb;function nb(e){return Fm.isMemo(e)?sb:Om[e.$$typeof]||c5}var f5=Object.defineProperty,d5=Object.getOwnPropertyNames,ob=Object.getOwnPropertySymbols,A5=Object.getOwnPropertyDescriptor,m5=Object.getPrototypeOf,ib=Object.prototype;function ab(e,t,r){if(typeof t!="string"){if(ib){var n=m5(t);n&&n!==ib&&ab(e,n,r)}var o=d5(t);ob&&(o=o.concat(ob(t)));for(var i=nb(e),s=nb(t),a=0;a<o.length;++a){var c=o[a];if(!l5[c]&&!(r&&r[c])&&!(s&&s[c])&&!(i&&i[c])){var l=A5(t,c);try{f5(e,c,l)}catch{}}}}return e}cb.exports=ab});function ri(e,t,r){var n="";return r.split(" ").forEach(function(o){e[o]!==void 0?t.push(e[o]+";"):o&&(n+=o+" ")}),n}var p5,vs,ni,Bs=m(()=>{p5=!0;vs=function(t,r,n){var o=t.key+"-"+r.name;(n===!1||p5===!1)&&t.registered[o]===void 0&&(t.registered[o]=r.styles)},ni=function(t,r,n){vs(t,r,n);var o=t.key+"-"+r.name;if(t.inserted[r.name]===void 0){var i=r;do t.insert(r===i?"."+o:"",i,t.sheet,!0),i=i.next;while(i!==void 0)}}});function ub(e){for(var t=0,r,n=0,o=e.length;o>=4;++n,o-=4)r=e.charCodeAt(n)&255|(e.charCodeAt(++n)&255)<<8|(e.charCodeAt(++n)&255)<<16|(e.charCodeAt(++n)&255)<<24,r=(r&65535)*1540483477+((r>>>16)*59797<<16),r^=r>>>24,t=(r&65535)*1540483477+((r>>>16)*59797<<16)^(t&65535)*1540483477+((t>>>16)*59797<<16);switch(o){case 3:t^=(e.charCodeAt(n+2)&255)<<16;case 2:t^=(e.charCodeAt(n+1)&255)<<8;case 1:t^=e.charCodeAt(n)&255,t=(t&65535)*1540483477+((t>>>16)*59797<<16)}return t^=t>>>13,t=(t&65535)*1540483477+((t>>>16)*59797<<16),((t^t>>>15)>>>0).toString(36)}var fb=m(()=>{});var db,Ab=m(()=>{db={animationIterationCount:1,aspectRatio:1,borderImageOutset:1,borderImageSlice:1,borderImageWidth:1,boxFlex:1,boxFlexGroup:1,boxOrdinalGroup:1,columnCount:1,columns:1,flex:1,flexGrow:1,flexPositive:1,flexShrink:1,flexNegative:1,flexOrder:1,gridRow:1,gridRowEnd:1,gridRowSpan:1,gridRowStart:1,gridColumn:1,gridColumnEnd:1,gridColumnSpan:1,gridColumnStart:1,msGridRow:1,msGridRowSpan:1,msGridColumn:1,msGridColumnSpan:1,fontWeight:1,lineHeight:1,opacity:1,order:1,orphans:1,scale:1,tabSize:1,widows:1,zIndex:1,zoom:1,WebkitLineClamp:1,fillOpacity:1,floodOpacity:1,stopOpacity:1,strokeDasharray:1,strokeDashoffset:1,strokeMiterlimit:1,strokeOpacity:1,strokeWidth:1}});function cc(e,t,r){if(r==null)return"";var n=r;if(n.__emotion_styles!==void 0)return n;switch(typeof r){case"boolean":return"";case"object":{var o=r;if(o.anim===1)return gn={name:o.name,styles:o.styles,next:gn},o.name;var i=r;if(i.styles!==void 0){var s=i.next;if(s!==void 0)for(;s!==void 0;)gn={name:s.name,styles:s.styles,next:gn},s=s.next;var a=i.styles+";";return a}return C5(e,t,r)}case"function":{if(e!==void 0){var c=gn,l=r(e);return gn=c,cc(e,t,l)}break}}var u=r;if(t==null)return u;var d=t[u];return d!==void 0?d:u}function C5(e,t,r){var n="";if(Array.isArray(r))for(var o=0;o<r.length;o++)n+=cc(e,t,r[o])+";";else for(var i in r){var s=r[i];if(typeof s!="object"){var a=s;t!=null&&t[a]!==void 0?n+=i+"{"+t[a]+"}":mb(a)&&(n+=Gm(i)+":"+pb(i,a)+";")}else{if(i==="NO_COMPONENT_SELECTOR"&&g5)throw new Error(x5);if(Array.isArray(s)&&typeof s[0]=="string"&&(t==null||t[s[0]]===void 0))for(var c=0;c<s.length;c++)mb(s[c])&&(n+=Gm(i)+":"+pb(i,s[c])+";");else{var l=cc(e,t,s);switch(i){case"animation":case"animationName":{n+=Gm(i)+":"+l+";";break}default:n+=i+"{"+l+"}"}}}}return n}function hn(e,t,r){if(e.length===1&&typeof e[0]=="object"&&e[0]!==null&&e[0].styles!==void 0)return e[0];var n=!0,o="";gn=void 0;var i=e[0];if(i==null||i.raw===void 0)n=!1,o+=cc(r,t,i);else{var s=i;o+=s[0]}for(var a=1;a<e.length;a++)if(o+=cc(r,t,e[a]),n){var c=i;o+=c[a]}gb.lastIndex=0;for(var l="",u;(u=gb.exec(o))!==null;)l+="-"+u[1];var d=ub(o)+l;return{name:d,styles:o,next:gn}}var g5,h5,y5,hb,mb,Gm,pb,x5,gb,gn,oi=m(()=>{fb();Ab();wu();g5=!1,h5=/[A-Z]|^ms/g,y5=/_EMO_([^_]+?)_([^]*?)_EMO_/g,hb=function(t){return t.charCodeAt(1)===45},mb=function(t){return t!=null&&typeof t!="boolean"},Gm=Eu(function(e){return hb(e)?e:e.replace(h5,"-$&").toLowerCase()}),pb=function(t,r){switch(t){case"animation":case"animationName":if(typeof r=="string")return r.replace(y5,function(n,o,i){return gn={name:o,styles:i,next:gn},o})}return db[t]!==1&&!hb(t)&&typeof r=="number"&&r!==0?r+"px":r},x5="Component selectors can only be used in conjunction with @emotion/babel-plugin, the swc Emotion plugin, or another Emotion-aware compiler transform.";gb=/label:\s*([^\s;{]+)\s*(;|$)/g});var Du,b5,E5,lc,uc=m(()=>{Du=p(Q()),b5=function(t){return t()},E5=Du.useInsertionEffect?Du.useInsertionEffect:!1,lc=E5||b5});var Ir,fc,yb,Hm,w5,Vm,dc,go,Nu,Um,xb,I5,S5,Cb,jm=m(()=>{Ir=p(Q()),fc=p(Q());Dm();nc();bu();Bs();oi();uc();yb=!1,Hm=Ir.createContext(typeof HTMLElement<"u"?XC({key:"css"}):null),w5=Hm.Provider,Vm=function(){return(0,fc.useContext)(Hm)},dc=function(t){return(0,fc.forwardRef)(function(r,n){var o=(0,fc.useContext)(Hm);return t(r,o,n)})},go=Ir.createContext({}),Nu={}.hasOwnProperty,Um="__EMOTION_TYPE_PLEASE_DO_NOT_USE__",xb=function(t,r){var n={};for(var o in r)Nu.call(r,o)&&(n[o]=r[o]);return n[Um]=t,n},I5=function(t){var r=t.cache,n=t.serialized,o=t.isStringTag;return vs(r,n,o),lc(function(){return ni(r,n,o)}),null},S5=dc(function(e,t,r){var n=e.css;typeof n=="string"&&t.registered[n]!==void 0&&(n=t.registered[n]);var o=e[Um],i=[n],s="";typeof e.className=="string"?s=ri(t.registered,i,e.className):e.className!=null&&(s=e.className+" ");var a=hn(i,void 0,Ir.useContext(go));s+=t.key+"-"+a.name;var c={};for(var l in e)Nu.call(e,l)&&l!=="css"&&l!==Um&&!yb&&(c[l]=e[l]);return c.className=s,r&&(c.ref=r),Ir.createElement(Ir.Fragment,null,Ir.createElement(I5,{cache:t,serialized:a,isStringTag:typeof o=="string"}),Ir.createElement(o,c))}),Cb=S5});function Eb(){for(var e=arguments.length,t=new Array(e),r=0;r<e;r++)t[r]=arguments[r];return hn(t)}function Lu(){var e=Eb.apply(void 0,arguments),t="animation-"+e.name;return{name:t,styles:"@keyframes "+t+"{"+e.styles+"}",anim:1,toString:function(){return"_EMO_"+this.name+"_"+this.styles+"_EMO_"}}}var Ts,vq,bb,Ac=m(()=>{jm();jm();Ts=p(Q());Bs();uc();oi();Dm();nc();bu();vq=p(lb()),bb=function(t,r){var n=arguments;if(r==null||!Nu.call(r,"css"))return Ts.createElement.apply(void 0,n);var o=n.length,i=new Array(o);i[0]=Cb,i[1]=xb(t,r);for(var s=2;s<o;s++)i[s]=n[s];return Ts.createElement.apply(null,i)};(function(e){var t;t||(t=e.JSX||(e.JSX={}))})(bb||(bb={}))});var v5,wb,$m=m(()=>{wu();v5=/^((children|dangerouslySetInnerHTML|key|ref|autoFocus|defaultValue|defaultChecked|innerHTML|suppressContentEditableWarning|suppressHydrationWarning|valueLink|abbr|accept|acceptCharset|accessKey|action|allow|allowUserMedia|allowPaymentRequest|allowFullScreen|allowTransparency|alt|async|autoComplete|autoPlay|capture|cellPadding|cellSpacing|challenge|charSet|checked|cite|classID|className|cols|colSpan|content|contentEditable|contextMenu|controls|controlsList|coords|crossOrigin|data|dateTime|decoding|default|defer|dir|disabled|disablePictureInPicture|disableRemotePlayback|download|draggable|encType|enterKeyHint|fetchpriority|fetchPriority|form|formAction|formEncType|formMethod|formNoValidate|formTarget|frameBorder|headers|height|hidden|high|href|hrefLang|htmlFor|httpEquiv|id|inputMode|integrity|is|keyParams|keyType|kind|label|lang|list|loading|loop|low|marginHeight|marginWidth|max|maxLength|media|mediaGroup|method|min|minLength|multiple|muted|name|nonce|noValidate|open|optimum|pattern|placeholder|playsInline|popover|popoverTarget|popoverTargetAction|poster|preload|profile|radioGroup|readOnly|referrerPolicy|rel|required|reversed|role|rows|rowSpan|sandbox|scope|scoped|scrolling|seamless|selected|shape|size|sizes|slot|span|spellCheck|src|srcDoc|srcLang|srcSet|start|step|style|summary|tabIndex|target|title|translate|type|useMap|value|width|wmode|wrap|about|datatype|inlist|prefix|property|resource|typeof|vocab|autoCapitalize|autoCorrect|autoSave|color|incremental|fallback|inert|itemProp|itemScope|itemType|itemID|itemRef|on|option|results|security|unselectable|accentHeight|accumulate|additive|alignmentBaseline|allowReorder|alphabetic|amplitude|arabicForm|ascent|attributeName|attributeType|autoReverse|azimuth|baseFrequency|baselineShift|baseProfile|bbox|begin|bias|by|calcMode|capHeight|clip|clipPathUnits|clipPath|clipRule|colorInterpolation|colorInterpolationFilters|colorProfile|colorRendering|contentScriptType|contentStyleType|cursor|cx|cy|d|decelerate|descent|diffuseConstant|direction|display|divisor|dominantBaseline|dur|dx|dy|edgeMode|elevation|enableBackground|end|exponent|externalResourcesRequired|fill|fillOpacity|fillRule|filter|filterRes|filterUnits|floodColor|floodOpacity|focusable|fontFamily|fontSize|fontSizeAdjust|fontStretch|fontStyle|fontVariant|fontWeight|format|from|fr|fx|fy|g1|g2|glyphName|glyphOrientationHorizontal|glyphOrientationVertical|glyphRef|gradientTransform|gradientUnits|hanging|horizAdvX|horizOriginX|ideographic|imageRendering|in|in2|intercept|k|k1|k2|k3|k4|kernelMatrix|kernelUnitLength|kerning|keyPoints|keySplines|keyTimes|lengthAdjust|letterSpacing|lightingColor|limitingConeAngle|local|markerEnd|markerMid|markerStart|markerHeight|markerUnits|markerWidth|mask|maskContentUnits|maskUnits|mathematical|mode|numOctaves|offset|opacity|operator|order|orient|orientation|origin|overflow|overlinePosition|overlineThickness|panose1|paintOrder|pathLength|patternContentUnits|patternTransform|patternUnits|pointerEvents|points|pointsAtX|pointsAtY|pointsAtZ|preserveAlpha|preserveAspectRatio|primitiveUnits|r|radius|refX|refY|renderingIntent|repeatCount|repeatDur|requiredExtensions|requiredFeatures|restart|result|rotate|rx|ry|scale|seed|shapeRendering|slope|spacing|specularConstant|specularExponent|speed|spreadMethod|startOffset|stdDeviation|stemh|stemv|stitchTiles|stopColor|stopOpacity|strikethroughPosition|strikethroughThickness|string|stroke|strokeDasharray|strokeDashoffset|strokeLinecap|strokeLinejoin|strokeMiterlimit|strokeOpacity|strokeWidth|surfaceScale|systemLanguage|tableValues|targetX|targetY|textAnchor|textDecoration|textRendering|textLength|to|transform|u1|u2|underlinePosition|underlineThickness|unicode|unicodeBidi|unicodeRange|unitsPerEm|vAlphabetic|vHanging|vIdeographic|vMathematical|values|vectorEffect|version|vertAdvY|vertOriginX|vertOriginY|viewBox|viewTarget|visibility|widths|wordSpacing|writingMode|x|xHeight|x1|x2|xChannelSelector|xlinkActuate|xlinkArcrole|xlinkHref|xlinkRole|xlinkShow|xlinkTitle|xlinkType|xmlBase|xmlns|xmlnsXlink|xmlLang|xmlSpace|y|y1|y2|yChannelSelector|z|zoomAndPan|for|class|autofocus)|(([Dd][Aa][Tt][Aa]|[Aa][Rr][Ii][Aa]|x)-.*))$/,wb=Eu(function(e){return v5.test(e)||e.charCodeAt(0)===111&&e.charCodeAt(1)===110&&e.charCodeAt(2)<91})});var ho,B5,T5,M5,Ib,Sb,R5,vb,Bb=m(()=>{nc();Ac();oi();uc();Bs();ho=p(Q());$m();B5=!1,T5=wb,M5=function(t){return t!=="theme"},Ib=function(t){return typeof t=="string"&&t.charCodeAt(0)>96?T5:M5},Sb=function(t,r,n){var o;if(r){var i=r.shouldForwardProp;o=t.__emotion_forwardProp&&i?function(s){return t.__emotion_forwardProp(s)&&i(s)}:i}return typeof o!="function"&&n&&(o=t.__emotion_forwardProp),o},R5=function(t){var r=t.cache,n=t.serialized,o=t.isStringTag;return vs(r,n,o),lc(function(){return ni(r,n,o)}),null},vb=function e(t,r){var n=t.__emotion_real===t,o=n&&t.__emotion_base||t,i,s;r!==void 0&&(i=r.label,s=r.target);var a=Sb(t,r,n),c=a||Ib(o),l=!c("as");return function(){var u=arguments,d=n&&t.__emotion_styles!==void 0?t.__emotion_styles.slice(0):[];if(i!==void 0&&d.push("label:"+i+";"),u[0]==null||u[0].raw===void 0)d.push.apply(d,u);else{var A=u[0];d.push(A[0]);for(var f=u.length,g=1;g<f;g++)d.push(u[g],A[g])}var h=dc(function(y,E,x){var S=l&&y.as||o,w="",I=[],v=y;if(y.theme==null){v={};for(var B in y)v[B]=y[B];v.theme=ho.useContext(go)}typeof y.className=="string"?w=ri(E.registered,I,y.className):y.className!=null&&(w=y.className+" ");var R=hn(d.concat(I),E.registered,v);w+=E.key+"-"+R.name,s!==void 0&&(w+=" "+s);var D=l&&a===void 0?Ib(S):c,L={};for(var F in y)l&&F==="as"||D(F)&&(L[F]=y[F]);return L.className=w,x&&(L.ref=x),ho.createElement(ho.Fragment,null,ho.createElement(R5,{cache:E,serialized:R,isStringTag:typeof S=="string"}),ho.createElement(S,L))});return h.displayName=i!==void 0?i:"Styled("+(typeof o=="string"?o:o.displayName||o.name||"Component")+")",h.defaultProps=t.defaultProps,h.__emotion_real=h,h.__emotion_base=o,h.__emotion_styles=d,h.__emotion_forwardProp=a,Object.defineProperty(h,"toString",{value:function(){return s===void 0&&B5?"NO_COMPONENT_SELECTOR":"."+s}}),h.withComponent=function(y,E){var x=e(y,rc({},r,E,{shouldForwardProp:Sb(h,E,!0)}));return x.apply(void 0,d)},h}}});var Vq,Q5,Pu,Tb=m(()=>{Bb();nc();oi();uc();Bs();Vq=p(Q());$m();Q5=["a","abbr","address","area","article","aside","audio","b","base","bdi","bdo","big","blockquote","body","br","button","canvas","caption","cite","code","col","colgroup","data","datalist","dd","del","details","dfn","dialog","div","dl","dt","em","embed","fieldset","figcaption","figure","footer","form","h1","h2","h3","h4","h5","h6","head","header","hgroup","hr","html","i","iframe","img","input","ins","kbd","keygen","label","legend","li","link","main","map","mark","marquee","menu","menuitem","meta","meter","nav","noscript","object","ol","optgroup","option","output","p","param","picture","pre","progress","q","rp","rt","ruby","s","samp","script","section","select","small","source","span","strong","style","sub","summary","sup","table","tbody","td","textarea","tfoot","th","thead","time","title","tr","track","u","ul","var","video","wbr","circle","clipPath","defs","ellipse","foreignObject","g","image","line","linearGradient","mask","path","pattern","polygon","polyline","radialGradient","rect","stop","svg","text","tspan"],Pu=vb.bind(null);Q5.forEach(function(e){Pu[e]=Pu(e)})});var O=K((Wq,Mb)=>{Mb.exports=JBrowseExports["react/jsx-runtime"]});function _5(e,t){return Pu(e,t)}function Qb(e,t){Array.isArray(e.__emotion_styles)&&(e.__emotion_styles=t(e.__emotion_styles))}function Hn(e){return Rb[0]=e,hn(Rb)}var Fu,Rb,mc=m(()=>{"use client";Tb();oi();Ac();Fu=_5;Rb=[]});var k5,_b,kb=m(()=>{k5={borderRadius:4},_b=k5});function Ms(e=8,t=Ja({spacing:e})){if(e.mui)return e;let r=(...n)=>(n.length===0?[1]:n).map(i=>{let s=t(i);return typeof s=="number"?`${s}px`:s}).join(" ");return r.mui=!0,r}var Wm=m(()=>{Xo()});function Ym(e,t){let r=this;if(r.vars){if(!r.colorSchemes?.[e]||typeof r.getColorSchemeSelector!="function")return{};let n=r.getColorSchemeSelector(e);return n==="&"?t:((n.includes("data-")||n.includes("."))&&(n=`*:where(${n.replace(/\s*&$/,"")}) &`),{[n]:t})}return r.palette.mode===e?t:{}}var Db=m(()=>{});function D5(e={},...t){let{breakpoints:r={},palette:n={},spacing:o,shape:i={},...s}=e,a=Wa(r),c=Ms(o),l=Ke({breakpoints:a,direction:"ltr",components:{},palette:{mode:"light",...n},spacing:c,shape:{..._b,...i}},s);return l=cu(l),l.applyStyles=Ym,l=t.reduce((u,d)=>Ke(u,d),l),l.unstable_sxConfig={...Un,...s?.unstable_sxConfig},l.unstable_sx=function(d){return Er({sx:d,theme:this})},l.internal_cache={},l}var ii,Nb=m(()=>{Gn();pm();lu();kb();Wm();Mm();du();Db();ii=D5});var Ou=m(()=>{Nb()});function N5(e){return Object.keys(e).length===0}function L5(e=null){let t=Lb.useContext(go);return!t||N5(t)?e:t}var Lb,qm,Pb=m(()=>{"use client";Lb=p(Q(),1);mc();qm=L5});var Fb=m(()=>{Pb()});function F5(e=P5){return qm(e)}var P5,zm,Jm=m(()=>{"use client";Ou();Fb();P5=ii();zm=F5});var Ob=m(()=>{Jm();Jm()});var O5,G5,U5,H5,V5,j5,$5,W5,Y5,q5,z5,J5,K5,Iz,Gb=m(()=>{pn();mo();O5=$({prop:"flexBasis"}),G5=$({prop:"flexDirection"}),U5=$({prop:"flexWrap"}),H5=$({prop:"justifyContent"}),V5=$({prop:"alignItems"}),j5=$({prop:"alignContent"}),$5=$({prop:"order"}),W5=$({prop:"flex"}),Y5=$({prop:"flexGrow"}),q5=$({prop:"flexShrink"}),z5=$({prop:"alignSelf"}),J5=$({prop:"justifyItems"}),K5=$({prop:"justifySelf"}),Iz=Ot(O5,G5,U5,H5,V5,j5,$5,W5,Y5,q5,z5,J5,K5)});var Ub=m(()=>{Gb()});var X5,Z5,e3,t3,r3,n3,Rz,Hb=m(()=>{pn();mo();X5=$({prop:"position"}),Z5=$({prop:"zIndex",themeKey:"zIndex"}),e3=$({prop:"top"}),t3=$({prop:"right"}),r3=$({prop:"bottom"}),n3=$({prop:"left"}),Rz=Ot(X5,Z5,e3,t3,r3,n3)});var Vb=m(()=>{Hb()});var o3,i3,s3,a3,c3,l3,u3,f3,d3,Lz,jb=m(()=>{pn();mo();o3=$({prop:"fontFamily",themeKey:"typography"}),i3=$({prop:"fontSize",themeKey:"typography"}),s3=$({prop:"fontStyle",themeKey:"typography"}),a3=$({prop:"fontWeight",themeKey:"typography"}),c3=$({prop:"letterSpacing"}),l3=$({prop:"textTransform"}),u3=$({prop:"lineHeight"}),f3=$({prop:"textAlign"}),d3=$({prop:"typography",cssProperty:!1,themeKey:"typography"}),Lz=Ot(d3,o3,i3,s3,a3,c3,u3,f3,l3)});var $b=m(()=>{jb()});var Wb,A3,m3,pc,Yb=m(()=>{Wb=e=>e,A3=()=>{let e=Wb;return{configure(t){e=t},generate(t){return e(t)},reset(){e=Wb}}},m3=A3(),pc=m3});var Km=m(()=>{Yb()});function Gu(e={}){let{themeId:t,defaultTheme:r,defaultClassName:n="MuiBox-root",generateClassName:o}=e,i=Fu("div",{shouldForwardProp:a=>a!=="theme"&&a!=="sx"&&a!=="as"})(Er);return qb.forwardRef(function(c,l){let u=zm(r),{className:d,component:A="div",...f}=c;return(0,zb.jsx)(i,{as:A,ref:l,className:cs(d,o?o(n):n),theme:t&&u[t]||u,...f})})}var qb,zb,Jb=m(()=>{"use client";qb=p(Q(),1);Yl();mc();tc();Ob();zb=p(O(),1)});var Kb=m(()=>{Jb()});function Rs(e,t,r="Mui"){let n=p3[t];return n?`${r}-${n}`:`${pc.generate(e)}-${t}`}var p3,Xm=m(()=>{Km();p3={active:"active",checked:"checked",completed:"completed",disabled:"disabled",error:"error",expanded:"expanded",focused:"focused",focusVisible:"focusVisible",open:"open",readOnly:"readOnly",required:"required",selected:"selected"}});var Zm=m(()=>{Xm();Xm()});function Sr(e,t,r="Mui"){let n={};return t.forEach(o=>{n[o]=Rs(e,o,r)}),n}var Xb=m(()=>{Zm()});var Qs=m(()=>{Xb()});var g3,Zb,ep=m(()=>{Qs();g3=Sr("MuiBox",["root"]),Zb=g3});var uJ,eE=m(()=>{"use client";Km();Kb();ep();uJ=Gu({defaultClassName:Zb.root,generateClassName:pc.generate})});var tE=m(()=>{eE();ep()});function gc(e){let{variants:t,...r}=e,n={variants:t,style:Hn(r),isProcessed:!0};return n.style===r||t&&t.forEach(o=>{typeof o.style!="function"&&(o.style=Hn(o.style))}),n}var tp=m(()=>{mc()});function rp(e){return e!=="ownerState"&&e!=="theme"&&e!=="sx"&&e!=="as"}function si(e,t){return t&&e&&typeof e=="object"&&e.styles&&!e.styles.startsWith("@layer")&&(e.styles=`@layer ${t}{${String(e.styles)}}`),e}function y3(e){return e?(t,r)=>r[e]:null}function x3(e,t,r){e.theme=ds(e.theme)?r:e.theme[t]||e.theme}function Uu(e,t,r){let n=typeof t=="function"?t(e):t;if(Array.isArray(n))return n.flatMap(o=>Uu(e,o,r));if(Array.isArray(n?.variants)){let o;if(n.isProcessed)o=r?si(n.style,r):n.style;else{let{variants:i,...s}=n;o=r?si(Hn(s),r):s}return rE(e,n.variants,[o],r)}return n?.isProcessed?r?si(Hn(n.style),r):n.style:r?si(Hn(n),r):n}function rE(e,t,r=[],n=void 0){let o;e:for(let i=0;i<t.length;i+=1){let s=t[i];if(typeof s.props=="function"){if(o??={...e,...e.ownerState,ownerState:e.ownerState},!s.props(o))continue}else for(let a in s.props)if(e[a]!==s.props[a]&&e.ownerState?.[a]!==s.props[a])continue e;typeof s.style=="function"?(o??={...e,...e.ownerState,ownerState:e.ownerState},r.push(n?si(Hn(s.style(o)),n):s.style(o))):r.push(n?si(Hn(s.style),n):s.style)}return r}function Hu(e={}){let{themeId:t,defaultTheme:r=h3,rootShouldForwardProp:n=rp,slotShouldForwardProp:o=rp}=e;function i(a){x3(a,t,r)}return(a,c={})=>{Qb(a,v=>v.filter(B=>B!==Er));let{name:l,slot:u,skipVariantsResolver:d,skipSx:A,overridesResolver:f=y3(E3(u)),...g}=c,h=l&&l.startsWith("Mui")||u?"components":"custom",y=d!==void 0?d:u&&u!=="Root"&&u!=="root"||!1,E=A||!1,x=rp;u==="Root"||u==="root"?x=n:u?x=o:b3(a)&&(x=void 0);let S=Fu(a,{shouldForwardProp:x,label:C3(l,u),...g}),w=v=>{if(v.__emotion_real===v)return v;if(typeof v=="function")return function(R){return Uu(R,v,R.theme.modularCssLayers?h:void 0)};if($r(v)){let B=gc(v);return function(D){return B.variants?Uu(D,B,D.theme.modularCssLayers?h:void 0):D.theme.modularCssLayers?si(B.style,h):B.style}}return v},I=(...v)=>{let B=[],R=v.map(w),D=[];if(B.push(i),l&&f&&D.push(function(M){let G=M.theme.components?.[l]?.styleOverrides;if(!G)return null;let j={};for(let oe in G)j[oe]=Uu(M,G[oe],M.theme.modularCssLayers?"theme":void 0);return f(M,j)}),l&&!y&&D.push(function(M){let G=M.theme?.components?.[l]?.variants;return G?rE(M,G,[],M.theme.modularCssLayers?"theme":void 0):null}),E||D.push(Er),Array.isArray(R[0])){let C=R.shift(),M=new Array(B.length).fill(""),k=new Array(D.length).fill(""),G;G=[...M,...C,...k],G.raw=[...M,...C.raw,...k],B.unshift(G)}let L=[...B,...R,...D],F=S(...L);return a.muiName&&(F.muiName=a.muiName),F};return S.withConfig&&(I.withConfig=S.withConfig),I}}function C3(e,t){return void 0}function b3(e){return typeof e=="string"&&e.charCodeAt(0)>96}function E3(e){return e&&e.charAt(0).toLowerCase()+e.slice(1)}var h3,np=m(()=>{mc();am();Gn();Ou();tc();tp();h3=ii()});var op=m(()=>{np();np()});function _s(e,t,r=!1){let n={...t};for(let o in e)if(Object.prototype.hasOwnProperty.call(e,o)){let i=o;if(i==="components"||i==="slots")n[i]={...e[i],...n[i]};else if(i==="componentsProps"||i==="slotProps"){let s=e[i],a=t[i];if(!a)n[i]=s||{};else if(!s)n[i]=a;else{n[i]={...a};for(let c in s)if(Object.prototype.hasOwnProperty.call(s,c)){let l=c;n[i][l]=_s(s[l],a[l],r)}}}else i==="className"&&r&&t.className!==void 0?n.className=cs(e?.className,t?.className):i==="style"&&r&&t.style?n.style={...e?.style,...t?.style}:n[i]===void 0&&(n[i]=e[i])}return n}var nE=m(()=>{Yl()});var oE=m(()=>{nE()});function w3(e,t=Number.MIN_SAFE_INTEGER,r=Number.MAX_SAFE_INTEGER){return Math.max(t,Math.min(e,r))}var ip,iE=m(()=>{ip=w3});var sE=m(()=>{iE()});function ap(e,t=0,r=1){return ip(e,t,r)}function I3(e){e=e.slice(1);let t=new RegExp(`.{1,${e.length>=6?2:1}}`,"g"),r=e.match(t);return r&&r[0].length===1&&(r=r.map(n=>n+n)),r?`rgb${r.length===4?"a":""}(${r.map((n,o)=>o<3?parseInt(n,16):Math.round(parseInt(n,16)/255*1e3)/1e3).join(", ")})`:""}function yo(e){if(e.type)return e;if(e.charAt(0)==="#")return yo(I3(e));let t=e.indexOf("("),r=e.substring(0,t);if(!["rgb","rgba","hsl","hsla","color"].includes(r))throw new Error(Xt(9,e));let n=e.substring(t+1,e.length-1),o;if(r==="color"){if(n=n.split(" "),o=n.shift(),n.length===4&&n[3].charAt(0)==="/"&&(n[3]=n[3].slice(1)),!["srgb","display-p3","a98-rgb","prophoto-rgb","rec-2020"].includes(o))throw new Error(Xt(10,o))}else n=n.split(",");return n=n.map(i=>parseFloat(i)),{type:r,values:n,colorSpace:o}}function Vu(e){let{type:t,colorSpace:r}=e,{values:n}=e;return t.includes("rgb")?n=n.map((o,i)=>i<3?parseInt(o,10):o):t.includes("hsl")&&(n[1]=`${n[1]}%`,n[2]=`${n[2]}%`),t.includes("color")?n=`${r} ${n.join(" ")}`:n=`${n.join(", ")}`,`${t}(${n})`}function cp(e){e=yo(e);let{values:t}=e,r=t[0],n=t[1]/100,o=t[2]/100,i=n*Math.min(o,1-o),s=(l,u=(l+r/30)%12)=>o-i*Math.max(Math.min(u-3,9-u,1),-1),a="rgb",c=[Math.round(s(0)*255),Math.round(s(8)*255),Math.round(s(4)*255)];return e.type==="hsla"&&(a+="a",c.push(t[3])),Vu({type:a,values:c})}function sp(e){e=yo(e);let t=e.type==="hsl"||e.type==="hsla"?yo(cp(e)).values:e.values;return t=t.map(r=>(e.type!=="color"&&(r/=255),r<=.03928?r/12.92:((r+.055)/1.055)**2.4)),Number((.2126*t[0]+.7152*t[1]+.0722*t[2]).toFixed(3))}function aE(e,t){let r=sp(e),n=sp(t);return(Math.max(r,n)+.05)/(Math.min(r,n)+.05)}function lp(e,t){return e=yo(e),t=ap(t),(e.type==="rgb"||e.type==="hsl")&&(e.type+="a"),e.type==="color"?e.values[3]=`/${t}`:e.values[3]=t,Vu(e)}function xo(e,t,r){try{return lp(e,t)}catch{return e}}function Ds(e,t){if(e=yo(e),t=ap(t),e.type.includes("hsl"))e.values[2]*=1-t;else if(e.type.includes("rgb")||e.type.includes("color"))for(let r=0;r<3;r+=1)e.values[r]*=1-t;return Vu(e)}function ce(e,t,r){try{return Ds(e,t)}catch{return e}}function Ns(e,t){if(e=yo(e),t=ap(t),e.type.includes("hsl"))e.values[2]+=(100-e.values[2])*t;else if(e.type.includes("rgb"))for(let r=0;r<3;r+=1)e.values[r]+=(255-e.values[r])*t;else if(e.type.includes("color"))for(let r=0;r<3;r+=1)e.values[r]+=(1-e.values[r])*t;return Vu(e)}function le(e,t,r){try{return Ns(e,t)}catch{return e}}function v3(e,t=.15){return sp(e)>.5?Ds(e,t):Ns(e,t)}function hc(e,t,r){try{return v3(e,t)}catch{return e}}var S3,ks,cE=m(()=>{ls();sE();S3=e=>{let t=yo(e);return t.values.slice(0,3).map((r,n)=>t.type.includes("hsl")&&n!==0?`${r}%`:r).join(" ")},ks=(e,t)=>{try{return S3(e)}catch{return e}}});var yc=m(()=>{cE()});var lE,B3,uE=m(()=>{"use client";lE=p(Q(),1),B3=p(O(),1)});function R3(e){let{theme:t,name:r,props:n}=e;if(!t||!t.components||!t.components[r])return n;let o=t.components[r];return o.defaultProps?_s(o.defaultProps,n,t.components.mergeClassNameAndStyle):!o.styleOverrides&&!o.variants?_s(o,n,t.components.mergeClassNameAndStyle):n}function up({props:e,name:t}){let r=ju.useContext(M3);return R3({props:e,name:t,theme:{components:r}})}var ju,T3,M3,fE=m(()=>{"use client";ju=p(Q(),1);oE();T3=p(O(),1),M3=ju.createContext(void 0)});var dE=m(()=>{fE()});function $u(e){let t,r;return function(o){let i=t;return(i===void 0||o.theme!==r)&&(AE.theme=o.theme,i=gc(e(AE)),t=i,r=o.theme),i}}var AE,mE=m(()=>{tp();AE={theme:void 0}});function Wu(e=""){function t(...n){if(!n.length)return"";let o=n[0];return typeof o=="string"&&!o.match(/(#|\(|\)|(-?(\d*\.)?\d+)(px|em|%|ex|ch|rem|vw|vh|vmin|vmax|cm|mm|in|pt|pc))|^(-?(\d*\.)?\d+)$|(\d+ \d+ \d+)/)?`, var(--${e?`${e}-`:""}${o}${t(...n.slice(1))})`:`, ${o}`}return(n,...o)=>`var(--${e?`${e}-`:""}${n}${t(...o)})`}var pE=m(()=>{});function xc(e,t){let{prefix:r,shouldSkipGeneratingVar:n}=t||{},o={},i={},s={};return _3(e,(a,c,l)=>{if((typeof c=="string"||typeof c=="number")&&(!n||!n(a,c))){let u=`--${r?`${r}-`:""}${a.join("-")}`,d=k3(a,c);Object.assign(o,{[u]:d}),gE(i,a,`var(${u})`,l),gE(s,a,`var(${u}, ${d})`,l)}},a=>a[0]==="vars"),{css:o,vars:i,varsWithDefaults:s}}var gE,_3,k3,hE=m(()=>{gE=(e,t,r,n=[])=>{let o=e;t.forEach((i,s)=>{s===t.length-1?Array.isArray(o)?o[Number(i)]=r:o&&typeof o=="object"&&(o[i]=r):o&&typeof o=="object"&&(o[i]||(o[i]=n.includes(i)?[]:{}),o=o[i])})},_3=(e,t,r)=>{function n(o,i=[],s=[]){Object.entries(o).forEach(([a,c])=>{(!r||r&&!r([...i,a]))&&c!=null&&(typeof c=="object"&&Object.keys(c).length>0?n(c,[...i,a],Array.isArray(c)?[...s,a]:s):t([...i,a],c,s))})}n(e)},k3=(e,t)=>typeof t=="number"?["lineHeight","fontWeight","opacity","zIndex"].some(n=>e.includes(n))||e[e.length-1].toLowerCase().includes("opacity")?t:`${t}px`:t});function D3(e,t={}){let{getSelector:r=E,disableCssColorScheme:n,colorSchemeSelector:o,enableContrastVars:i}=t,{colorSchemes:s={},components:a,defaultColorScheme:c="light",...l}=e,{vars:u,css:d,varsWithDefaults:A}=xc(l,t),f=A,g={},{[c]:h,...y}=s;if(Object.entries(y||{}).forEach(([w,I])=>{let{vars:v,css:B,varsWithDefaults:R}=xc(I,t);f=Ke(f,R),g[w]={css:B,vars:v}}),h){let{css:w,vars:I,varsWithDefaults:v}=xc(h,t);f=Ke(f,v),g[c]={css:w,vars:I}}function E(w,I){let v=o;if(o==="class"&&(v=".%s"),o==="data"&&(v="[data-%s]"),o?.startsWith("data-")&&!o.includes("%s")&&(v=`[${o}="%s"]`),w){if(v==="media")return e.defaultColorScheme===w?":root":{[`@media (prefers-color-scheme: ${s[w]?.palette?.mode||w})`]:{":root":I}};if(v)return e.defaultColorScheme===w?`:root, ${v.replace("%s",String(w))}`:v.replace("%s",String(w))}return":root"}return{vars:f,generateThemeVars:()=>{let w={...u};return Object.entries(g).forEach(([,{vars:I}])=>{w=Ke(w,I)}),w},generateStyleSheets:()=>{let w=[],I=e.defaultColorScheme||"light";function v(D,L){Object.keys(L).length&&w.push(typeof D=="string"?{[D]:{...L}}:D)}v(r(void 0,{...d}),d);let{[I]:B,...R}=g;if(B){let{css:D}=B,L=s[I]?.palette?.mode,F=!n&&L?{colorScheme:L,...D}:{...D};v(r(I,{...F}),F)}return Object.entries(R).forEach(([D,{css:L}])=>{let F=s[D]?.palette?.mode,C=!n&&F?{colorScheme:F,...L}:{...L};v(r(D,{...C}),C)}),i&&w.push({":root":{"--__l-threshold":"0.7","--__l":"clamp(0, (l / var(--__l-threshold) - 1) * -infinity, 1)","--__a":"clamp(0.87, (l / var(--__l-threshold) - 1) * -infinity, 1)"}}),w}}}var fp,yE=m(()=>{Gn();hE();fp=D3});function dp(e){return function(r){return e==="media"?`@media (prefers-color-scheme: ${r})`:e?e.startsWith("data-")&&!e.includes("%s")?`[${e}="${r}"] &`:e==="class"?`.${r} &`:e==="data"?`[data-${r}] &`:`${e.replace("%s",r)} &`:"&"}}var xE=m(()=>{});var CE=m(()=>{});var eK,bE=m(()=>{Qs();eK=Sr("MuiContainer",["root","disableGutters","fixed","maxWidthXs","maxWidthSm","maxWidthMd","maxWidthLg","maxWidthXl"])});var EE=m(()=>{bE()});var wE=m(()=>{});var N3,L3,P3,Cc,iK,IE=m(()=>{Qs();N3=[0,1,2,3,4,5,6,7,8,9,10],L3=["column-reverse","column","row-reverse","row"],P3=["nowrap","wrap-reverse","wrap"],Cc=["auto","grow",1,2,3,4,5,6,7,8,9,10,11,12],iK=Sr("MuiGrid",["root","container","item",...N3.map(e=>`spacing-xs-${e}`),...L3.map(e=>`direction-xs-${e}`),...P3.map(e=>`wrap-xs-${e}`),...Cc.map(e=>`grid-xs-${e}`),...Cc.map(e=>`grid-sm-${e}`),...Cc.map(e=>`grid-md-${e}`),...Cc.map(e=>`grid-lg-${e}`),...Cc.map(e=>`grid-xl-${e}`)])});var SE=m(()=>{wE();IE()});var vE=m(()=>{});var fK,BE=m(()=>{Qs();fK=Sr("MuiStack",["root"])});var TE=m(()=>{vE();BE()});var Ap=m(()=>{Sm();Ub();vm();Bm();Vb();Tm();Xo();$b();tE();op();Wm();yc();mE();pE();uE();CE();EE();SE();TE();});var F3,Ls,ME=m(()=>{F3={black:"#000",white:"#fff"},Ls=F3});var O3,RE,QE=m(()=>{O3={50:"#fafafa",100:"#f5f5f5",200:"#eeeeee",300:"#e0e0e0",400:"#bdbdbd",500:"#9e9e9e",600:"#757575",700:"#616161",800:"#424242",900:"#212121",A100:"#f5f5f5",A200:"#eeeeee",A400:"#bdbdbd",A700:"#616161"},RE=O3});var G3,ai,_E=m(()=>{G3={50:"#f3e5f5",100:"#e1bee7",200:"#ce93d8",300:"#ba68c8",400:"#ab47bc",500:"#9c27b0",600:"#8e24aa",700:"#7b1fa2",800:"#6a1b9a",900:"#4a148c",A100:"#ea80fc",A200:"#e040fb",A400:"#d500f9",A700:"#aa00ff"},ai=G3});var U3,Wr,mp=m(()=>{U3={50:"#ffebee",100:"#ffcdd2",200:"#ef9a9a",300:"#e57373",400:"#ef5350",500:"#f44336",600:"#e53935",700:"#d32f2f",800:"#c62828",900:"#b71c1c",A100:"#ff8a80",A200:"#ff5252",A400:"#ff1744",A700:"#d50000"},Wr=U3});var H3,Vn,pp=m(()=>{H3={50:"#fff3e0",100:"#ffe0b2",200:"#ffcc80",300:"#ffb74d",400:"#ffa726",500:"#ff9800",600:"#fb8c00",700:"#f57c00",800:"#ef6c00",900:"#e65100",A100:"#ffd180",A200:"#ffab40",A400:"#ff9100",A700:"#ff6d00"},Vn=H3});var V3,yn,gp=m(()=>{V3={50:"#e3f2fd",100:"#bbdefb",200:"#90caf9",300:"#64b5f6",400:"#42a5f5",500:"#2196f3",600:"#1e88e5",700:"#1976d2",800:"#1565c0",900:"#0d47a1",A100:"#82b1ff",A200:"#448aff",A400:"#2979ff",A700:"#2962ff"},yn=V3});var j3,ci,kE=m(()=>{j3={50:"#e1f5fe",100:"#b3e5fc",200:"#81d4fa",300:"#4fc3f7",400:"#29b6f6",500:"#03a9f4",600:"#039be5",700:"#0288d1",800:"#0277bd",900:"#01579b",A100:"#80d8ff",A200:"#40c4ff",A400:"#00b0ff",A700:"#0091ea"},ci=j3});var $3,xn,hp=m(()=>{$3={50:"#e8f5e9",100:"#c8e6c9",200:"#a5d6a7",300:"#81c784",400:"#66bb6a",500:"#4caf50",600:"#43a047",700:"#388e3c",800:"#2e7d32",900:"#1b5e20",A100:"#b9f6ca",A200:"#69f0ae",A400:"#00e676",A700:"#00c853"},xn=$3});function LE(){return{text:{primary:"rgba(0, 0, 0, 0.87)",secondary:"rgba(0, 0, 0, 0.6)",disabled:"rgba(0, 0, 0, 0.38)"},divider:"rgba(0, 0, 0, 0.12)",background:{paper:Ls.white,default:Ls.white},action:{active:"rgba(0, 0, 0, 0.54)",hover:"rgba(0, 0, 0, 0.04)",hoverOpacity:.04,selected:"rgba(0, 0, 0, 0.08)",selectedOpacity:.08,disabled:"rgba(0, 0, 0, 0.26)",disabledBackground:"rgba(0, 0, 0, 0.12)",disabledOpacity:.38,focus:"rgba(0, 0, 0, 0.12)",focusOpacity:.12,activatedOpacity:.12}}}function PE(){return{text:{primary:Ls.white,secondary:"rgba(255, 255, 255, 0.7)",disabled:"rgba(255, 255, 255, 0.5)",icon:"rgba(255, 255, 255, 0.5)"},divider:"rgba(255, 255, 255, 0.12)",background:{paper:"#121212",default:"#121212"},action:{active:Ls.white,hover:"rgba(255, 255, 255, 0.08)",hoverOpacity:.08,selected:"rgba(255, 255, 255, 0.16)",selectedOpacity:.16,disabled:"rgba(255, 255, 255, 0.3)",disabledBackground:"rgba(255, 255, 255, 0.12)",disabledOpacity:.38,focus:"rgba(255, 255, 255, 0.12)",focusOpacity:.12,activatedOpacity:.24}}}function DE(e,t,r,n){let o=n.light||n,i=n.dark||n*1.5;e[t]||(e.hasOwnProperty(r)?e[t]=e[r]:t==="light"?e.light=Ns(e.main,o):t==="dark"&&(e.dark=Ds(e.main,i)))}function NE(e,t,r,n,o){let i=o.light||o,s=o.dark||o*1.5;t[r]||(t.hasOwnProperty(n)?t[r]=t[n]:r==="light"?t.light=`color-mix(in ${e}, ${t.main}, #fff ${(i*100).toFixed(0)}%)`:r==="dark"&&(t.dark=`color-mix(in ${e}, ${t.main}, #000 ${(s*100).toFixed(0)}%)`))}function W3(e="light"){return e==="dark"?{main:yn[200],light:yn[50],dark:yn[400]}:{main:yn[700],light:yn[400],dark:yn[800]}}function Y3(e="light"){return e==="dark"?{main:ai[200],light:ai[50],dark:ai[400]}:{main:ai[500],light:ai[300],dark:ai[700]}}function q3(e="light"){return e==="dark"?{main:Wr[500],light:Wr[300],dark:Wr[700]}:{main:Wr[700],light:Wr[400],dark:Wr[800]}}function z3(e="light"){return e==="dark"?{main:ci[400],light:ci[300],dark:ci[700]}:{main:ci[700],light:ci[500],dark:ci[900]}}function J3(e="light"){return e==="dark"?{main:xn[400],light:xn[300],dark:xn[700]}:{main:xn[800],light:xn[500],dark:xn[900]}}function K3(e="light"){return e==="dark"?{main:Vn[400],light:Vn[300],dark:Vn[700]}:{main:"#ed6c02",light:Vn[500],dark:Vn[900]}}function X3(e){return`oklch(from ${e} var(--__l) 0 h / var(--__a))`}function li(e){let{mode:t="light",contrastThreshold:r=3,tonalOffset:n=.2,colorSpace:o,...i}=e,s=e.primary||W3(t),a=e.secondary||Y3(t),c=e.error||q3(t),l=e.info||z3(t),u=e.success||J3(t),d=e.warning||K3(t);function A(y){return o?X3(y):aE(y,Yu.text.primary)>=r?Yu.text.primary:yp.text.primary}let f=({color:y,name:E,mainShade:x=500,lightShade:S=300,darkShade:w=700})=>{if(y={...y},!y.main&&y[x]&&(y.main=y[x]),!y.hasOwnProperty("main"))throw new Error(Xt(11,E?` (${E})`:"",x));if(typeof y.main!="string")throw new Error(Xt(12,E?` (${E})`:"",JSON.stringify(y.main)));return o?(NE(o,y,"light",S,n),NE(o,y,"dark",w,n)):(DE(y,"light",S,n),DE(y,"dark",w,n)),y.contrastText||(y.contrastText=A(y.main)),y},g;return t==="light"?g=LE():t==="dark"&&(g=PE()),Ke({common:{...Ls},mode:t,primary:f({color:s,name:"primary"}),secondary:f({color:a,name:"secondary",mainShade:"A400",lightShade:"A200",darkShade:"A700"}),error:f({color:c,name:"error"}),warning:f({color:d,name:"warning"}),info:f({color:l,name:"info"}),success:f({color:u,name:"success"}),grey:RE,contrastThreshold:r,getContrastText:A,augmentColor:f,tonalOffset:n,...g},i)}var yp,Yu,bc=m(()=>{ls();Gn();yc();ME();QE();_E();mp();pp();gp();kE();hp();yp=LE();Yu=PE()});function qu(e){let t={};return Object.entries(e).forEach(n=>{let[o,i]=n;typeof i=="object"&&(t[o]=`${i.fontStyle?`${i.fontStyle} `:""}${i.fontVariant?`${i.fontVariant} `:""}${i.fontWeight?`${i.fontWeight} `:""}${i.fontStretch?`${i.fontStretch} `:""}${i.fontSize||""}${i.lineHeight?`/${i.lineHeight} `:""}${i.fontFamily||""}`)}),t}var FE=m(()=>{});var OE=m(()=>{yE();FE();xE()});function xp(e,t){return{toolbar:{minHeight:56,[e.up("xs")]:{"@media (orientation: landscape)":{minHeight:48}},[e.up("sm")]:{minHeight:64}},...t}}var GE=m(()=>{});function Z3(e){return Math.round(e*1e5)/1e5}function Cp(e,t){let{fontFamily:r=HE,fontSize:n=14,fontWeightLight:o=300,fontWeightRegular:i=400,fontWeightMedium:s=500,fontWeightBold:a=700,htmlFontSize:c=16,allVariants:l,pxToRem:u,...d}=typeof t=="function"?t(e):t,A=n/14,f=u||(y=>`${y/c*A}rem`),g=(y,E,x,S,w)=>({fontFamily:r,fontWeight:y,fontSize:f(E),lineHeight:x,...r===HE?{letterSpacing:`${Z3(S/E)}em`}:{},...w,...l}),h={h1:g(o,96,1.167,-1.5),h2:g(o,60,1.2,-.5),h3:g(i,48,1.167,0),h4:g(i,34,1.235,.25),h5:g(i,24,1.334,0),h6:g(s,20,1.6,.15),subtitle1:g(i,16,1.75,.15),subtitle2:g(s,14,1.57,.1),body1:g(i,16,1.5,.15),body2:g(i,14,1.43,.15),button:g(s,14,1.75,.4,UE),caption:g(i,12,1.66,.4),overline:g(i,12,2.66,1,UE),inherit:{fontFamily:"inherit",fontWeight:"inherit",fontSize:"inherit",lineHeight:"inherit",letterSpacing:"inherit"}};return Ke({htmlFontSize:c,pxToRem:f,fontFamily:r,fontSize:n,fontWeightLight:o,fontWeightRegular:i,fontWeightMedium:s,fontWeightBold:a,...h},d,{clone:!1})}var UE,HE,VE=m(()=>{Gn();UE={textTransform:"uppercase"},HE='"Roboto", "Helvetica", "Arial", sans-serif'});function Ne(...e){return[`${e[0]}px ${e[1]}px ${e[2]}px ${e[3]}px rgba(0,0,0,${.2})`,`${e[4]}px ${e[5]}px ${e[6]}px ${e[7]}px rgba(0,0,0,${.14})`,`${e[8]}px ${e[9]}px ${e[10]}px ${e[11]}px rgba(0,0,0,${.12})`].join(",")}var e4,jE,$E=m(()=>{e4=["none",Ne(0,2,1,-1,0,1,1,0,0,1,3,0),Ne(0,3,1,-2,0,2,2,0,0,1,5,0),Ne(0,3,3,-2,0,3,4,0,0,1,8,0),Ne(0,2,4,-1,0,4,5,0,0,1,10,0),Ne(0,3,5,-1,0,5,8,0,0,1,14,0),Ne(0,3,5,-1,0,6,10,0,0,1,18,0),Ne(0,4,5,-2,0,7,10,1,0,2,16,1),Ne(0,5,5,-3,0,8,10,1,0,3,14,2),Ne(0,5,6,-3,0,9,12,1,0,3,16,2),Ne(0,6,6,-3,0,10,14,1,0,4,18,3),Ne(0,6,7,-4,0,11,15,1,0,4,20,3),Ne(0,7,8,-4,0,12,17,2,0,5,22,4),Ne(0,7,8,-4,0,13,19,2,0,5,24,4),Ne(0,7,9,-4,0,14,21,2,0,5,26,4),Ne(0,8,9,-5,0,15,22,2,0,6,28,5),Ne(0,8,10,-5,0,16,24,2,0,6,30,5),Ne(0,8,11,-5,0,17,26,2,0,6,32,5),Ne(0,9,11,-5,0,18,28,2,0,7,34,6),Ne(0,9,12,-6,0,19,29,2,0,7,36,6),Ne(0,10,13,-6,0,20,31,3,0,8,38,7),Ne(0,10,13,-6,0,21,33,3,0,8,40,7),Ne(0,10,14,-6,0,22,35,3,0,8,42,7),Ne(0,11,14,-7,0,23,36,3,0,9,44,8),Ne(0,11,15,-7,0,24,38,3,0,9,46,8)],jE=e4});function WE(e){return`${Math.round(e)}ms`}function i4(e){if(!e)return 0;let t=e/36;return Math.min(Math.round((4+15*t**.25+t/5)*10),3e3)}function bp(e){let t={...e};delete t.reducedMotion;let r={...n4,...t.easing},n={...o4,...t.duration},o=(s=t4,a=r4)=>{let{duration:c=n.standard,easing:l=r.easeInOut,delay:u=0,...d}=a;return(Array.isArray(s)?s:[s]).map(A=>`${A} ${typeof c=="string"?c:WE(c)} ${l} ${typeof u=="string"?u:WE(u)}`).join(",")},i=t.create??o;return{getAutoHeightDuration:i4,create:i,...t,easing:r,duration:n}}var t4,r4,n4,o4,YE=m(()=>{t4=["all"],r4={},n4={easeInOut:"cubic-bezier(0.4, 0, 0.2, 1)",easeOut:"cubic-bezier(0.0, 0, 0.2, 1)",easeIn:"cubic-bezier(0.4, 0, 1, 1)",sharp:"cubic-bezier(0.4, 0, 0.6, 1)"},o4={shortest:150,shorter:200,short:250,standard:300,complex:375,enteringScreen:225,leavingScreen:195}});function Ep(e=s4){return{reducedMotion:"never",...e}}var s4,qE=m(()=>{s4={}});var a4,zE,JE=m(()=>{a4={mobileStepper:1e3,fab:1050,speedDial:1050,appBar:1100,drawer:1200,modal:1300,snackbar:1400,tooltip:1500},zE=a4});function c4(e){return $r(e)||typeof e>"u"||typeof e=="string"||typeof e=="boolean"||typeof e=="number"||Array.isArray(e)}function zu(e={}){let t={...e};function r(n){let o=Object.entries(n);for(let i=0;i<o.length;i++){let[s,a]=o[i];!c4(a)||s.startsWith("unstable_")||s.startsWith("internal_")?delete n[s]:$r(a)&&(n[s]={...a},r(n[s]))}}return r(t),`import { unstable_createBreakpoints as createBreakpoints, createTransitions } from '@mui/material/styles';
+"use strict";var JBrowsePluginMsaView=(()=>{var oO=Object.create;var Zl=Object.defineProperty;var iO=Object.getOwnPropertyDescriptor;var sO=Object.getOwnPropertyNames;var aO=Object.getPrototypeOf,cO=Object.prototype.hasOwnProperty;var m=(e,t,r)=>()=>{if(r)throw r[0];try{return e&&(t=e(e=0)),t}catch(n){throw r=[n],n}};var X=(e,t)=>()=>{try{return t||e((t={exports:{}}).exports,t),t.exports}catch(r){throw t=0,r}},Bt=(e,t)=>{for(var r in t)Zl(e,r,{get:t[r],enumerable:!0})},nC=(e,t,r,n)=>{if(t&&typeof t=="object"||typeof t=="function")for(let o of sO(t))!cO.call(e,o)&&o!==r&&Zl(e,o,{get:()=>t[o],enumerable:!(n=iO(t,o))||n.enumerable});return e};var p=(e,t,r)=>(r=e!=null?oO(aO(e)):{},nC(t||!e||!e.__esModule?Zl(r,"default",{value:e,enumerable:!0}):r,e)),lO=e=>nC(Zl({},"__esModule",{value:!0}),e);var iC=X((J$,oC)=>{oC.exports=JBrowseExports["@jbrowse/core/Plugin"]});var ss=X((K$,sC)=>{sC.exports=JBrowseExports["@jbrowse/core/configuration"]});var be=X((X$,aC)=>{aC.exports=JBrowseExports["@jbrowse/core/util"]});var zt=X((Z$,cC)=>{cC.exports=JBrowseExports["mobx-state-tree"]});var Q=X((eW,lC)=>{lC.exports=JBrowseExports.react});function uC(e){var t,r,n="";if(typeof e=="string"||typeof e=="number")n+=e;else if(typeof e=="object")if(Array.isArray(e)){var o=e.length;for(t=0;t<o;t++)e[t]&&(r=uC(e[t]))&&(n&&(n+=" "),n+=r)}else for(r in e)e[r]&&(n&&(n+=" "),n+=r);return n}function uO(){for(var e,t,r=0,n="",o=arguments.length;r<o;r++)(e=arguments[r])&&(t=uC(e))&&(n&&(n+=" "),n+=t);return n}var as,eu=m(()=>{as=uO});function tu(e,t,r=void 0){let n={};for(let o in e){let i=e[o],s="",a=!0;for(let c=0;c<i.length;c+=1){let l=i[c];l&&(s+=(a===!0?"":" ")+t(l),a=!1,r&&r[l]&&(s+=" "+r[l]))}n[o]=s}return n}var fC=m(()=>{});var dC=m(()=>{fC()});function Jt(e,...t){let r=new URL(`https://mui.com/production-error/?code=${e}`);return t.forEach(n=>r.searchParams.append("args[]",n)),`Minified MUI error #${e}; visit ${r} for the full message.`}var AC=m(()=>{});var cs=m(()=>{AC()});function ls(e){if(typeof e!="string")throw new Error(Jt(7));return e.charAt(0).toUpperCase()+e.slice(1)}var mC=m(()=>{cs()});var Am=m(()=>{mC()});var qa,pC=m(()=>{Am();qa=ls});function Fr(e,t){let r=Array.isArray(t),n=Array.isArray(e);return pO(t)?t:gO(e)?us(t):r&&n?AO(e,t):r!==n?us(t):hO(e,t)}function fO(e){let t=0,r=e.length,n=new Array(r);for(t=0;t<r;t+=1)n[t]=us(e[t]);return n}function dO(e){let t={};for(let r in e)r==="__proto__"||r==="constructor"||r==="prototype"||(t[r]=us(e[r]));return t}function AO(e,t){let r=e.length;for(let n=0;n<t.length;n+=1)e[r+n]=us(t[n]);return e}function mO(e){return typeof e=="object"&&e!==null&&!(e instanceof RegExp)&&!(e instanceof Date)}function pO(e){return typeof e!="object"||e===null}function gO(e){return typeof e!="object"||e===null||e instanceof RegExp||e instanceof Date}function us(e){return mO(e)?Array.isArray(e)?fO(e):dO(e):e}function hO(e,t){for(let r in t)r==="__proto__"||r==="constructor"||r==="prototype"||(r in e?e[r]=Fr(e[r],t[r]):e[r]=us(t[r]));return e}var gC=m(()=>{});var ru=m(()=>{gC()});function fs(e){if(e==null)return!0;for(let t in e)return!1;return!0}var hC=m(()=>{});var mm=m(()=>{hC()});var yC=X(Ce=>{"use strict";var pm=Symbol.for("react.transitional.element"),gm=Symbol.for("react.portal"),nu=Symbol.for("react.fragment"),ou=Symbol.for("react.strict_mode"),iu=Symbol.for("react.profiler"),su=Symbol.for("react.consumer"),au=Symbol.for("react.context"),cu=Symbol.for("react.forward_ref"),lu=Symbol.for("react.suspense"),uu=Symbol.for("react.suspense_list"),fu=Symbol.for("react.memo"),du=Symbol.for("react.lazy"),yO=Symbol.for("react.view_transition"),xO=Symbol.for("react.client.reference");function pr(e){if(typeof e=="object"&&e!==null){var t=e.$$typeof;switch(t){case pm:switch(e=e.type,e){case nu:case iu:case ou:case lu:case uu:case yO:return e;default:switch(e=e&&e.$$typeof,e){case au:case cu:case du:case fu:return e;case su:return e;default:return t}}case gm:return t}}}Ce.ContextConsumer=su;Ce.ContextProvider=au;Ce.Element=pm;Ce.ForwardRef=cu;Ce.Fragment=nu;Ce.Lazy=du;Ce.Memo=fu;Ce.Portal=gm;Ce.Profiler=iu;Ce.StrictMode=ou;Ce.Suspense=lu;Ce.SuspenseList=uu;Ce.isContextConsumer=function(e){return pr(e)===su};Ce.isContextProvider=function(e){return pr(e)===au};Ce.isElement=function(e){return typeof e=="object"&&e!==null&&e.$$typeof===pm};Ce.isForwardRef=function(e){return pr(e)===cu};Ce.isFragment=function(e){return pr(e)===nu};Ce.isLazy=function(e){return pr(e)===du};Ce.isMemo=function(e){return pr(e)===fu};Ce.isPortal=function(e){return pr(e)===gm};Ce.isProfiler=function(e){return pr(e)===iu};Ce.isStrictMode=function(e){return pr(e)===ou};Ce.isSuspense=function(e){return pr(e)===lu};Ce.isSuspenseList=function(e){return pr(e)===uu};Ce.isValidElementType=function(e){return typeof e=="string"||typeof e=="function"||e===nu||e===iu||e===ou||e===lu||e===uu||typeof e=="object"&&e!==null&&(e.$$typeof===du||e.$$typeof===fu||e.$$typeof===au||e.$$typeof===su||e.$$typeof===cu||e.$$typeof===xO||e.getModuleId!==void 0)};Ce.typeOf=pr});var CC=X((EW,xC)=>{"use strict";xC.exports=yC()});function Pr(e){if(typeof e!="object"||e===null)return!1;let t=Object.getPrototypeOf(e);return(t===null||t===Object.prototype||Object.getPrototypeOf(t)===null)&&!(Symbol.toStringTag in e)&&!(Symbol.iterator in e)}function EC(e){if(hm.isValidElement(e)||(0,ym.isValidElementType)(e)||!Pr(e))return e;let t={};return Object.keys(e).forEach(r=>{t[r]=EC(e[r])}),t}function Je(e,t,r={clone:!0}){let n=r.clone?{...e}:e;return Pr(e)&&Pr(t)&&Object.keys(t).forEach(o=>{hm.isValidElement(t[o])||(0,ym.isValidElementType)(t[o])?n[o]=t[o]:Pr(t[o])&&Object.prototype.hasOwnProperty.call(e,o)&&Pr(e[o])?n[o]=Je(e[o],t[o],r):r.clone?n[o]=Pr(t[o])?EC(t[o]):t[o]:n[o]=t[o]}),n}var hm,ym,xm=m(()=>{hm=p(Q(),1),ym=p(CC(),1)});var Fn=m(()=>{xm();xm()});function Au(e,t){if(!e.containerQueries||!CO(t))return t;let r=[];for(let o in t)o.startsWith("@container")&&r.push(o);r.sort((o,i)=>+(o.match(bC)?.[1]||0)-+(i.match(bC)?.[1]||0));let n=t;for(let o=0;o<r.length;o+=1){let i=r[o],s=n[i];delete n[i],n[i]=s}return n}function CO(e){for(let t in e)if(t.startsWith("@container"))return!0;return!1}function mu(e,t){return t==="@"||t.startsWith("@")&&(e.some(r=>t.startsWith(`@${r}`))||!!t.match(/^@\d/))}function Cm(e,t){let r=t.match(/^@([^/]+)?\/?(.+)?$/);if(!r)return null;let[,n,o]=r,i=Number.isNaN(+n)?n||0:+n;return e.containerQueries(o).up(i)}function pu(e){let t=(i,s)=>i.replace("@media",s?`@container ${s}`:"@container");function r(i,s){i.up=(...a)=>t(e.breakpoints.up(...a),s),i.down=(...a)=>t(e.breakpoints.down(...a),s),i.between=(...a)=>t(e.breakpoints.between(...a),s),i.only=(...a)=>t(e.breakpoints.only(...a),s),i.not=(...a)=>{let c=t(e.breakpoints.not(...a),s);return c.includes("not all and")?c.replace("not all and ","").replace("min-width:","width<").replace("max-width:","width>").replace("and","or"):c}}let n={},o=i=>(r(n,i),n);return r(o),{...e,containerQueries:o}}var bC,Em=m(()=>{bC=/min-width:\s*([0-9.]+)/});var gu=m(()=>{Em();Em()});function za(e){let{values:t={xs:0,sm:600,md:900,lg:1200,xl:1536},unit:r="px",step:n=5,...o}=e,i=EO(t),s=Object.keys(i);function a(f){return`@media (min-width:${typeof t[f]=="number"?t[f]:f}${r})`}function c(f){return`@media (max-width:${(typeof t[f]=="number"?t[f]:f)-n/100}${r})`}function l(f,g){let h=s.indexOf(g);return`@media (min-width:${typeof t[f]=="number"?t[f]:f}${r}) and (max-width:${(h!==-1&&typeof t[s[h]]=="number"?t[s[h]]:g)-n/100}${r})`}function u(f){return s.indexOf(f)+1<s.length?l(f,s[s.indexOf(f)+1]):a(f)}function d(f){let g=s.indexOf(f);return g===0?a(s[1]):g===s.length-1?c(s[g]):l(f,s[s.indexOf(f)+1]).replace("@media","@media not all and")}let A=[];for(let f=0;f<s.length;f+=1)A.push(a(s[f]));return{keys:s,values:i,up:a,down:c,between:l,only:u,not:d,unit:r,internal_mediaKeys:A,...o}}var EO,bm=m(()=>{EO=e=>{let t=Object.keys(e).map(r=>({key:r,val:e[r]}))||[];return t.sort((r,n)=>r.val-n.val),t.reduce((r,n)=>({...r,[n.key]:n.val}),{})}});function cn(e,t,r){let n={};return ds(n,e.theme,t,(o,i,s)=>{let a=r(i,s);o?n[o]=a:Fr(n,a)})}function ds(e,t,r,n){if(t??=bO,Array.isArray(r)){let o=t.breakpoints??Ja;for(let i=0;i<r.length;i+=1)wm(e,o.up(o.keys[i]),r[i],void 0,n);return e}if(typeof r=="object"){let o=t.breakpoints??Ja,i=o.values??Ka;for(let s in r)if(mu(o.keys,s)){let a=Cm(t.containerQueries?t:wO,s);a&&wm(e,a,r[s],s,n)}else if(s in i){let a=o.up(s);wm(e,a,r[s],s,n)}else{let a=s;e[a]=r[a]}return e}return n(void 0,r),e}function wm(e,t,r,n,o){e[t]??={},o(t,r,n)}function wC(e=Ja){let{internal_mediaKeys:t}=e,r={};for(let n=0;n<t.length;n+=1)r[t[n]]={};return r}function Im(e,t){let r=e.internal_mediaKeys;for(let n=0;n<r.length;n+=1){let o=r[n];fs(t[o])&&delete t[o]}return t}function IC(e,t){if(Array.isArray(t))return!0;if(typeof t=="object"&&t!==null){for(let n=0;n<e.keys.length;n+=1)if(e.keys[n]in t)return!0;let r=Object.keys(t);for(let n=0;n<r.length;n+=1)if(mu(e.keys,r[n]))return!0}return!1}var bO,Ka,Ja,wO,SC=m(()=>{mm();ru();gu();bm();bO={},Ka={xs:0,sm:600,md:900,lg:1200,xl:1536},Ja=za({values:Ka}),wO={containerQueries:e=>({up:t=>{let r=typeof t=="number"?t:Ka[t]||t;return typeof r=="number"&&(r=`${r}px`),e?`@container ${e} (min-width:${r})`:`@container (min-width:${r})`}})}});var lo=m(()=>{SC()});function Sm(e,t,r,n){let o;return typeof e=="function"?o=e(r):Array.isArray(e)?o=e[r]||r:typeof r=="string"?o=As(e,r,!0,n)||r:o=r,t&&(o=t(o,r,e)),o}function As(e,t,r=!0,n=void 0){if(!e||!t)return null;let o=t.split(".");if(e.vars&&r){let i=vC(e.vars,o,n);if(i!=null)return i}return vC(e,o,n)}function vC(e,t,r=void 0){let n,o=e,i=0;for(;i<t.length;){if(o==null)return o;n=o,o=o[t[i]],i+=1}if(r&&o===void 0){let s=t[t.length-1],a=`${r}${s==="default"?"":ls(s)}`;return n?.[a]}return o}function $(e){let{prop:t,cssProperty:r=e.prop,themeKey:n,transform:o}=e,i=s=>{if(s[t]==null)return null;let a=s[t],c=s.theme,l=As(c,n)||{};return cn(s,a,d=>{let A=Sm(l,o,d,t);return r===!1?A:{[r]:A}})};return i.propTypes={},i.filterProps=[t],i}var vm=m(()=>{Am();lo()});var ln=m(()=>{vm();vm()});function qo(e,t,r,n){let o=As(e,t,!0)??r;return typeof o=="number"||typeof o=="string"?i=>typeof i=="string"?i:typeof o=="string"?o.startsWith("var(")&&i===0?0:o.startsWith("var(")&&i===1?o:`calc(${i} * ${o})`:o*i:Array.isArray(o)?i=>{if(typeof i=="string")return i;let s=Math.abs(i),a=o[s];return i>=0?a:typeof a=="number"?-a:typeof a=="string"&&a.startsWith("var(")?`calc(-1 * ${a})`:`-${a}`}:typeof o=="function"?o:()=>{}}function Za(e){return qo(e,"spacing",8,"spacing")}function zo(e,t){return typeof t=="string"||t==null?t:e(t)}function Mm(e,t){let r=e.theme??SO,n=r?.internal_cache?.unarySpacing??Za(r),o={};for(let i in e){if(!t.has(i))continue;let s=Xa[i]??(MC[0]=i,MC),a=e[i];ds(o,e.theme,a,(c,l)=>{let u=c?o[c]:o;for(let d=0;d<s.length;d+=1)u[s[d]]=zo(n,l)})}return o}function Rm(e){return Mm(e,Bm)}function Qm(e){return Mm(e,Tm)}function QC(e){return Mm(e,RC)}var SO,hu,BC,TC,Xa,Bm,Tm,RC,MC,$e,We,_C=m(()=>{lo();ln();SO={internal_cache:{}},hu={m:"margin",p:"padding"},BC={t:"Top",r:"Right",b:"Bottom",l:"Left",x:["Left","Right"],y:["Top","Bottom"]},TC={marginX:"mx",marginY:"my",paddingX:"px",paddingY:"py"},Xa={};for(let e in hu)Xa[e]=[hu[e]];for(let e in hu)for(let t in BC){let r=hu[e],n=BC[t],o=Array.isArray(n)?n.map(i=>r+i):[r+n];Xa[e+t]=o}for(let e in TC)Xa[e]=Xa[TC[e]];Bm=new Set(["m","mt","mr","mb","ml","mx","my","margin","marginTop","marginRight","marginBottom","marginLeft","marginX","marginY","marginInline","marginInlineStart","marginInlineEnd","marginBlock","marginBlockStart","marginBlockEnd"]),Tm=new Set(["p","pt","pr","pb","pl","px","py","padding","paddingTop","paddingRight","paddingBottom","paddingLeft","paddingX","paddingY","paddingInline","paddingInlineStart","paddingInlineEnd","paddingBlock","paddingBlockStart","paddingBlockEnd"]),RC=new Set([...Bm,...Tm]);MC=[""];Rm.propTypes={};Rm.filterProps=Bm;$e=Rm;Qm.propTypes={};Qm.filterProps=Tm;We=Qm;QC.propTypes={};QC.filterProps=RC});var Jo=m(()=>{_C()});function vO(...e){let t=e.reduce((n,o)=>(o.filterProps.forEach(i=>{n[i]=o}),n),{}),r=n=>{let o={};for(let i in n)t[i]&&Fr(o,t[i](n));return o};return r.propTypes={},r.filterProps=e.reduce((n,o)=>n.concat(o.filterProps),[]),r}var Ft,kC=m(()=>{ru();Ft=vO});var uo=m(()=>{kC()});function rr(e){return typeof e!="number"?e:`${e}px solid`}function gr(e,t){return $({prop:e,themeKey:"borders",transform:t})}var BO,TO,MO,RO,QO,_O,kO,DO,NO,LO,FO,PO,ec,rY,DC=m(()=>{ln();uo();Jo();lo();BO=gr("border",rr),TO=gr("borderTop",rr),MO=gr("borderRight",rr),RO=gr("borderBottom",rr),QO=gr("borderLeft",rr),_O=gr("borderColor"),kO=gr("borderTopColor"),DO=gr("borderRightColor"),NO=gr("borderBottomColor"),LO=gr("borderLeftColor"),FO=gr("outline",rr),PO=gr("outlineColor"),ec=e=>{if(e.borderRadius!==void 0&&e.borderRadius!==null){let t=qo(e.theme,"shape.borderRadius",4,"borderRadius"),r=n=>({borderRadius:zo(t,n)});return cn(e,e.borderRadius,r)}return null};ec.propTypes={};ec.filterProps=["borderRadius"];rY=Ft(BO,TO,MO,RO,QO,_O,kO,DO,NO,LO,ec,FO,PO)});var _m=m(()=>{DC()});var tc,rc,nc,OO,GO,UO,HO,VO,jO,$O,WO,YO,uY,NC=m(()=>{ln();uo();Jo();lo();tc=e=>{if(e.gap!==void 0&&e.gap!==null){let t=qo(e.theme,"spacing",8,"gap"),r=n=>({gap:zo(t,n)});return cn(e,e.gap,r)}return null};tc.propTypes={};tc.filterProps=["gap"];rc=e=>{if(e.columnGap!==void 0&&e.columnGap!==null){let t=qo(e.theme,"spacing",8,"columnGap"),r=n=>({columnGap:zo(t,n)});return cn(e,e.columnGap,r)}return null};rc.propTypes={};rc.filterProps=["columnGap"];nc=e=>{if(e.rowGap!==void 0&&e.rowGap!==null){let t=qo(e.theme,"spacing",8,"rowGap"),r=n=>({rowGap:zo(t,n)});return cn(e,e.rowGap,r)}return null};nc.propTypes={};nc.filterProps=["rowGap"];OO=$({prop:"gridColumn"}),GO=$({prop:"gridRow"}),UO=$({prop:"gridAutoFlow"}),HO=$({prop:"gridAutoColumns"}),VO=$({prop:"gridAutoRows"}),jO=$({prop:"gridTemplateColumns"}),$O=$({prop:"gridTemplateRows"}),WO=$({prop:"gridTemplateAreas"}),YO=$({prop:"gridArea"}),uY=Ft(tc,rc,nc,OO,GO,UO,HO,VO,jO,$O,WO,YO)});var km=m(()=>{NC()});function Ko(e,t){return t==="grey"?t:e}var qO,zO,JO,gY,LC=m(()=>{ln();uo();qO=$({prop:"color",themeKey:"palette",transform:Ko}),zO=$({prop:"bgcolor",cssProperty:"backgroundColor",themeKey:"palette",transform:Ko}),JO=$({prop:"backgroundColor",themeKey:"palette",transform:Ko}),gY=Ft(qO,zO,JO)});var Dm=m(()=>{LC()});function Kt(e){return e<=1&&e!==0?`${e*100}%`:e}var KO,XO,yu,ZO,e5,t5,r5,wY,IY,n5,SY,FC=m(()=>{ln();uo();lo();lo();KO=Ka;XO=$({prop:"width",transform:Kt}),yu=e=>{if(e.maxWidth!==void 0&&e.maxWidth!==null){let t=r=>{let n=e.theme?.breakpoints?.values?.[r]||KO[r];return n?e.theme?.breakpoints?.unit!=="px"?{maxWidth:`${n}${e.theme.breakpoints.unit}`}:{maxWidth:n}:{maxWidth:Kt(r)}};return cn(e,e.maxWidth,t)}return null};yu.filterProps=["maxWidth"];ZO=$({prop:"minWidth",transform:Kt}),e5=$({prop:"height",transform:Kt}),t5=$({prop:"maxHeight",transform:Kt}),r5=$({prop:"minHeight",transform:Kt}),wY=$({prop:"size",cssProperty:"width",transform:Kt}),IY=$({prop:"size",cssProperty:"height",transform:Kt}),n5=$({prop:"boxSizing"}),SY=Ft(XO,yu,ZO,e5,t5,r5,n5)});var Nm=m(()=>{FC()});var o5,Pn,xu=m(()=>{Jo();_m();km();Dm();Nm();o5={border:{themeKey:"borders",transform:rr},borderTop:{themeKey:"borders",transform:rr},borderRight:{themeKey:"borders",transform:rr},borderBottom:{themeKey:"borders",transform:rr},borderLeft:{themeKey:"borders",transform:rr},borderColor:{themeKey:"palette"},borderTopColor:{themeKey:"palette"},borderRightColor:{themeKey:"palette"},borderBottomColor:{themeKey:"palette"},borderLeftColor:{themeKey:"palette"},outline:{themeKey:"borders",transform:rr},outlineColor:{themeKey:"palette"},borderRadius:{themeKey:"shape.borderRadius",style:ec},color:{themeKey:"palette",transform:Ko},bgcolor:{themeKey:"palette",cssProperty:"backgroundColor",transform:Ko},backgroundColor:{themeKey:"palette",transform:Ko},p:{style:We},pt:{style:We},pr:{style:We},pb:{style:We},pl:{style:We},px:{style:We},py:{style:We},padding:{style:We},paddingTop:{style:We},paddingRight:{style:We},paddingBottom:{style:We},paddingLeft:{style:We},paddingX:{style:We},paddingY:{style:We},paddingInline:{style:We},paddingInlineStart:{style:We},paddingInlineEnd:{style:We},paddingBlock:{style:We},paddingBlockStart:{style:We},paddingBlockEnd:{style:We},m:{style:$e},mt:{style:$e},mr:{style:$e},mb:{style:$e},ml:{style:$e},mx:{style:$e},my:{style:$e},margin:{style:$e},marginTop:{style:$e},marginRight:{style:$e},marginBottom:{style:$e},marginLeft:{style:$e},marginX:{style:$e},marginY:{style:$e},marginInline:{style:$e},marginInlineStart:{style:$e},marginInlineEnd:{style:$e},marginBlock:{style:$e},marginBlockStart:{style:$e},marginBlockEnd:{style:$e},displayPrint:{cssProperty:!1,transform:e=>({"@media print":{display:e}})},display:{},overflow:{},textOverflow:{},visibility:{},whiteSpace:{},flexBasis:{},flexDirection:{},flexWrap:{},justifyContent:{},alignItems:{},alignContent:{},order:{},flex:{},flexGrow:{},flexShrink:{},alignSelf:{},justifyItems:{},justifySelf:{},gap:{style:tc},rowGap:{style:nc},columnGap:{style:rc},gridColumn:{},gridRow:{},gridAutoFlow:{},gridAutoColumns:{},gridAutoRows:{},gridTemplateColumns:{},gridTemplateRows:{},gridTemplateAreas:{},gridArea:{},position:{},zIndex:{themeKey:"zIndex"},top:{},right:{},bottom:{},left:{},boxShadow:{themeKey:"shadows"},width:{transform:Kt},maxWidth:{style:yu},minWidth:{transform:Kt},height:{transform:Kt},maxHeight:{transform:Kt},minHeight:{transform:Kt},boxSizing:{},font:{themeKey:"font"},fontFamily:{themeKey:"typography"},fontSize:{themeKey:"typography"},fontStyle:{themeKey:"typography"},fontWeight:{themeKey:"typography"},letterSpacing:{},textTransform:{},lineHeight:{},textAlign:{},typography:{cssProperty:!1,themeKey:"typography"}},Pn=o5});function s5(){function e(t){if(!t.sx)return null;let{sx:r,theme:n=i5,nested:o}=t,i=n.unstable_sxConfig??Pn,s={sx:null,theme:n,nested:!0};function a(c){let l=c;if(typeof c=="function")l=c(n);else if(typeof c!="object")return c;if(!l)return null;let u=n.breakpoints??Ja,d=wC(u);for(let A in l){let f=a5(l[A],n);if(f!=null){if(typeof f!="object"){PC(d,A,f,n,i);continue}if(i[A]){PC(d,A,f,n,i);continue}IC(u,f)?ds(d,t.theme,f,(g,h)=>{d[g][A]=h}):(s.sx=f,d[A]=e(s))}}return!o&&n.modularCssLayers?{"@layer sx":Au(n,Im(u,d))}:Au(n,Im(u,d))}return Array.isArray(r)?r.map(a):a(r)}return e.filterProps=["sx"],e}function PC(e,t,r,n,o){let i=o[t];if(!i){e[t]=r;return}if(r==null)return;let{themeKey:s}=i;if(s==="typography"&&r==="inherit"){e[t]=r;return}let{style:a}=i;if(a){Fr(e,a({[t]:r,theme:n}));return}let{cssProperty:c=t,transform:l}=i,u=As(n,s);ds(e,n,r,(d,A)=>{let f=Sm(u,l,A,t);c===!1?d?Fr(e[d],f):Fr(e,f):d?e[d][c]=f:e[c]=f})}function a5(e,t){return typeof e=="function"?e(t):e}var i5,hr,Lm=m(()=>{ru();ln();lo();gu();xu();i5={};hr=s5()});var oc=m(()=>{Lm();xu()});function ic(){return ic=Object.assign?Object.assign.bind():function(e){for(var t=1;t<arguments.length;t++){var r=arguments[t];for(var n in r)({}).hasOwnProperty.call(r,n)&&(e[n]=r[n])}return e},ic.apply(null,arguments)}var sc=m(()=>{});function l5(e){if(e.sheet)return e.sheet;for(var t=0;t<document.styleSheets.length;t++)if(document.styleSheets[t].ownerNode===e)return document.styleSheets[t]}function u5(e){var t=document.createElement("style");return t.setAttribute("data-emotion",e.key),e.nonce!==void 0&&t.setAttribute("nonce",e.nonce),t.appendChild(document.createTextNode("")),t.setAttribute("data-s",""),t}var c5,OC,GC=m(()=>{c5=!1;OC=(function(){function e(r){var n=this;this._insertTag=function(o){var i;n.tags.length===0?n.insertionPoint?i=n.insertionPoint.nextSibling:n.prepend?i=n.container.firstChild:i=n.before:i=n.tags[n.tags.length-1].nextSibling,n.container.insertBefore(o,i),n.tags.push(o)},this.isSpeedy=r.speedy===void 0?!c5:r.speedy,this.tags=[],this.ctr=0,this.nonce=r.nonce,this.key=r.key,this.container=r.container,this.prepend=r.prepend,this.insertionPoint=r.insertionPoint,this.before=null}var t=e.prototype;return t.hydrate=function(n){n.forEach(this._insertTag)},t.insert=function(n){this.ctr%(this.isSpeedy?65e3:1)===0&&this._insertTag(u5(this));var o=this.tags[this.tags.length-1];if(this.isSpeedy){var i=l5(o);try{i.insertRule(n,i.cssRules.length)}catch{}}else o.appendChild(document.createTextNode(n));this.ctr++},t.flush=function(){this.tags.forEach(function(n){var o;return(o=n.parentNode)==null?void 0:o.removeChild(n)}),this.tags=[],this.ctr=0},e})()});var yt,ac,se,Cu,ms,ps,UC,Eu,HC,bu=m(()=>{yt="-ms-",ac="-moz-",se="-webkit-",Cu="comm",ms="rule",ps="decl",UC="@import",Eu="@keyframes",HC="@layer"});function $C(e,t){return Ye(e,0)^45?(((t<<2^Ye(e,0))<<2^Ye(e,1))<<2^Ye(e,2))<<2^Ye(e,3):0}function wu(e){return e.trim()}function Fm(e,t){return(e=t.exec(e))?e[0]:e}function re(e,t,r){return e.replace(t,r)}function cc(e,t){return e.indexOf(t)}function Ye(e,t){return e.charCodeAt(t)|0}function fo(e,t,r){return e.slice(t,r)}function Pt(e){return e.length}function gs(e){return e.length}function hs(e,t){return t.push(e),e}function Pm(e,t){return e.map(t).join("")}var VC,Xo,jC,ys=m(()=>{VC=Math.abs,Xo=String.fromCharCode,jC=Object.assign});function lc(e,t,r,n,o,i,s){return{value:e,root:t,parent:r,type:n,props:o,children:i,line:Iu,column:xs,length:s,return:""}}function bs(e,t){return jC(lc("",null,null,"",null,null,0),e,{length:-e.length},t)}function YC(){return Ke}function qC(){return Ke=Ot>0?Ye(Es,--Ot):0,xs--,Ke===10&&(xs=1,Iu--),Ke}function Gt(){return Ke=Ot<WC?Ye(Es,Ot++):0,xs++,Ke===10&&(xs=1,Iu++),Ke}function yr(){return Ye(Es,Ot)}function uc(){return Ot}function ws(e,t){return fo(Es,e,t)}function Cs(e){switch(e){case 0:case 9:case 10:case 13:case 32:return 5;case 33:case 43:case 44:case 47:case 62:case 64:case 126:case 59:case 123:case 125:return 4;case 58:return 3;case 34:case 39:case 40:case 91:return 2;case 41:case 93:return 1}return 0}function Su(e){return Iu=xs=1,WC=Pt(Es=e),Ot=0,[]}function vu(e){return Es="",e}function Is(e){return wu(ws(Ot-1,Om(e===91?e+2:e===40?e+1:e)))}function zC(e){for(;(Ke=yr())&&Ke<33;)Gt();return Cs(e)>2||Cs(Ke)>3?"":" "}function JC(e,t){for(;--t&&Gt()&&!(Ke<48||Ke>102||Ke>57&&Ke<65||Ke>70&&Ke<97););return ws(e,uc()+(t<6&&yr()==32&&Gt()==32))}function Om(e){for(;Gt();)switch(Ke){case e:return Ot;case 34:case 39:e!==34&&e!==39&&Om(Ke);break;case 40:e===41&&Om(e);break;case 92:Gt();break}return Ot}function KC(e,t){for(;Gt()&&e+Ke!==57;)if(e+Ke===84&&yr()===47)break;return"/*"+ws(t,Ot-1)+"*"+Xo(e===47?e:Gt())}function XC(e){for(;!Cs(yr());)Gt();return ws(e,Ot)}var Iu,xs,WC,Ot,Ke,Es,Gm=m(()=>{ys();Iu=1,xs=1,WC=0,Ot=0,Ke=0,Es=""});function tE(e){return vu(Bu("",null,null,null,[""],e=Su(e),0,[0],e))}function Bu(e,t,r,n,o,i,s,a,c){for(var l=0,u=0,d=s,A=0,f=0,g=0,h=1,x=1,w=1,y=0,v="",b=o,I=i,S=n,B=v;x;)switch(g=y,y=Gt()){case 40:if(g!=108&&Ye(B,d-1)==58){cc(B+=re(Is(y),"&","&\f"),"&\f")!=-1&&(w=-1);break}case 34:case 39:case 91:B+=Is(y);break;case 9:case 10:case 13:case 32:B+=zC(g);break;case 92:B+=JC(uc()-1,7);continue;case 47:switch(yr()){case 42:case 47:hs(f5(KC(Gt(),uc()),t,r),c);break;default:B+="/"}break;case 123*h:a[l++]=Pt(B)*w;case 125*h:case 59:case 0:switch(y){case 0:case 125:x=0;case 59+u:w==-1&&(B=re(B,/\f/g,"")),f>0&&Pt(B)-d&&hs(f>32?eE(B+";",n,r,d-1):eE(re(B," ","")+";",n,r,d-2),c);break;case 59:B+=";";default:if(hs(S=ZC(B,t,r,l,u,o,a,v,b=[],I=[],d),i),y===123)if(u===0)Bu(B,t,S,S,b,i,d,a,I);else switch(A===99&&Ye(B,3)===110?100:A){case 100:case 108:case 109:case 115:Bu(e,S,S,n&&hs(ZC(e,S,S,0,0,o,a,v,o,b=[],d),I),o,I,d,a,n?b:I);break;default:Bu(B,S,S,S,[""],I,0,a,I)}}l=u=f=0,h=w=1,v=B="",d=s;break;case 58:d=1+Pt(B),f=g;default:if(h<1){if(y==123)--h;else if(y==125&&h++==0&&qC()==125)continue}switch(B+=Xo(y),y*h){case 38:w=u>0?1:(B+="\f",-1);break;case 44:a[l++]=(Pt(B)-1)*w,w=1;break;case 64:yr()===45&&(B+=Is(Gt())),A=yr(),u=d=Pt(v=B+=XC(uc())),y++;break;case 45:g===45&&Pt(B)==2&&(h=0)}}return i}function ZC(e,t,r,n,o,i,s,a,c,l,u){for(var d=o-1,A=o===0?i:[""],f=gs(A),g=0,h=0,x=0;g<n;++g)for(var w=0,y=fo(e,d+1,d=VC(h=s[g])),v=e;w<f;++w)(v=wu(h>0?A[w]+" "+y:re(y,/&\f/g,A[w])))&&(c[x++]=v);return lc(e,t,r,o===0?ms:a,c,l,u)}function f5(e,t,r){return lc(e,t,r,Cu,Xo(YC()),fo(e,2,-2),0)}function eE(e,t,r,n){return lc(e,t,r,ps,fo(e,0,n),fo(e,n+1,-1),n)}var rE=m(()=>{bu();ys();Gm()});var nE=m(()=>{});function Zo(e,t){for(var r="",n=gs(e),o=0;o<n;o++)r+=t(e[o],o,e,t)||"";return r}function oE(e,t,r,n){switch(e.type){case HC:if(e.children.length)break;case UC:case ps:return e.return=e.return||e.value;case Cu:return"";case Eu:return e.return=e.value+"{"+Zo(e.children,n)+"}";case ms:e.value=e.props.join(",")}return Pt(r=Zo(e.children,n))?e.return=e.value+"{"+r+"}":""}var iE=m(()=>{bu();ys()});function sE(e){var t=gs(e);return function(r,n,o,i){for(var s="",a=0;a<t;a++)s+=e[a](r,n,o,i)||"";return s}}function aE(e){return function(t){t.root||(t=t.return)&&e(t)}}var cE=m(()=>{ys()});var lE=m(()=>{bu();ys();rE();nE();Gm();iE();cE()});var Tu=m(()=>{});function Mu(e){var t=Object.create(null);return function(r){return t[r]===void 0&&(t[r]=e(r)),t[r]}}var Ru=m(()=>{});function fE(e,t){switch($C(e,t)){case 5103:return se+"print-"+e+e;case 5737:case 4201:case 3177:case 3433:case 1641:case 4457:case 2921:case 5572:case 6356:case 5844:case 3191:case 6645:case 3005:case 6391:case 5879:case 5623:case 6135:case 4599:case 4855:case 4215:case 6389:case 5109:case 5365:case 5621:case 3829:return se+e+e;case 5349:case 4246:case 4810:case 6968:case 2756:return se+e+ac+e+yt+e+e;case 6828:case 4268:return se+e+yt+e+e;case 6165:return se+e+yt+"flex-"+e+e;case 5187:return se+e+re(e,/(\w+).+(:[^]+)/,se+"box-$1$2"+yt+"flex-$1$2")+e;case 5443:return se+e+yt+"flex-item-"+re(e,/flex-|-self/,"")+e;case 4675:return se+e+yt+"flex-line-pack"+re(e,/align-content|flex-|-self/,"")+e;case 5548:return se+e+yt+re(e,"shrink","negative")+e;case 5292:return se+e+yt+re(e,"basis","preferred-size")+e;case 6060:return se+"box-"+re(e,"-grow","")+se+e+yt+re(e,"grow","positive")+e;case 4554:return se+re(e,/([^-])(transform)/g,"$1"+se+"$2")+e;case 6187:return re(re(re(e,/(zoom-|grab)/,se+"$1"),/(image-set)/,se+"$1"),e,"")+e;case 5495:case 3959:return re(e,/(image-set\([^]*)/,se+"$1$`$1");case 4968:return re(re(e,/(.+:)(flex-)?(.*)/,se+"box-pack:$3"+yt+"flex-pack:$3"),/s.+-b[^;]+/,"justify")+se+e+e;case 4095:case 3583:case 4068:case 2532:return re(e,/(.+)-inline(.+)/,se+"$1$2")+e;case 8116:case 7059:case 5753:case 5535:case 5445:case 5701:case 4933:case 4677:case 5533:case 5789:case 5021:case 4765:if(Pt(e)-1-t>6)switch(Ye(e,t+1)){case 109:if(Ye(e,t+4)!==45)break;case 102:return re(e,/(.+:)(.+)-([^]+)/,"$1"+se+"$2-$3$1"+ac+(Ye(e,t+3)==108?"$3":"$2-$3"))+e;case 115:return~cc(e,"stretch")?fE(re(e,"stretch","fill-available"),t)+e:e}break;case 4949:if(Ye(e,t+1)!==115)break;case 6444:switch(Ye(e,Pt(e)-3-(~cc(e,"!important")&&10))){case 107:return re(e,":",":"+se)+e;case 101:return re(e,/(.+:)([^;!]+)(;|!.+)?/,"$1"+se+(Ye(e,14)===45?"inline-":"")+"box$3$1"+se+"$2$3$1"+yt+"$2box$3")+e}break;case 5936:switch(Ye(e,t+11)){case 114:return se+e+yt+re(e,/[svh]\w+-[tblr]{2}/,"tb")+e;case 108:return se+e+yt+re(e,/[svh]\w+-[tblr]{2}/,"tb-rl")+e;case 45:return se+e+yt+re(e,/[svh]\w+-[tblr]{2}/,"lr")+e}return se+e+yt+e+e}return e}var d5,A5,m5,uE,p5,g5,h5,y5,dE,Um=m(()=>{GC();lE();Tu();Ru();d5=function(t,r,n){for(var o=0,i=0;o=i,i=yr(),o===38&&i===12&&(r[n]=1),!Cs(i);)Gt();return ws(t,Ot)},A5=function(t,r){var n=-1,o=44;do switch(Cs(o)){case 0:o===38&&yr()===12&&(r[n]=1),t[n]+=d5(Ot-1,r,n);break;case 2:t[n]+=Is(o);break;case 4:if(o===44){t[++n]=yr()===58?"&\f":"",r[n]=t[n].length;break}default:t[n]+=Xo(o)}while(o=Gt());return t},m5=function(t,r){return vu(A5(Su(t),r))},uE=new WeakMap,p5=function(t){if(!(t.type!=="rule"||!t.parent||t.length<1)){for(var r=t.value,n=t.parent,o=t.column===n.column&&t.line===n.line;n.type!=="rule";)if(n=n.parent,!n)return;if(!(t.props.length===1&&r.charCodeAt(0)!==58&&!uE.get(n))&&!o){uE.set(t,!0);for(var i=[],s=m5(r,i),a=n.props,c=0,l=0;c<s.length;c++)for(var u=0;u<a.length;u++,l++)t.props[l]=i[c]?s[c].replace(/&\f/g,a[u]):a[u]+" "+s[c]}}},g5=function(t){if(t.type==="decl"){var r=t.value;r.charCodeAt(0)===108&&r.charCodeAt(2)===98&&(t.return="",t.value="")}};h5=function(t,r,n,o){if(t.length>-1&&!t.return)switch(t.type){case ps:t.return=fE(t.value,t.length);break;case Eu:return Zo([bs(t,{value:re(t.value,"@","@"+se)})],o);case ms:if(t.length)return Pm(t.props,function(i){switch(Fm(i,/(::plac\w+|:read-\w+)/)){case":read-only":case":read-write":return Zo([bs(t,{props:[re(i,/:(read-\w+)/,":"+ac+"$1")]})],o);case"::placeholder":return Zo([bs(t,{props:[re(i,/:(plac\w+)/,":"+se+"input-$1")]}),bs(t,{props:[re(i,/:(plac\w+)/,":"+ac+"$1")]}),bs(t,{props:[re(i,/:(plac\w+)/,yt+"input-$1")]})],o)}return""})}},y5=[h5],dE=function(t){var r=t.key;if(r==="css"){var n=document.querySelectorAll("style[data-emotion]:not([data-s])");Array.prototype.forEach.call(n,function(h){var x=h.getAttribute("data-emotion");x.indexOf(" ")!==-1&&(document.head.appendChild(h),h.setAttribute("data-s",""))})}var o=t.stylisPlugins||y5,i={},s,a=[];s=t.container||document.head,Array.prototype.forEach.call(document.querySelectorAll('style[data-emotion^="'+r+' "]'),function(h){for(var x=h.getAttribute("data-emotion").split(" "),w=1;w<x.length;w++)i[x[w]]=!0;a.push(h)});var c,l=[p5,g5];{var u,d=[oE,aE(function(h){u.insert(h)})],A=sE(l.concat(o,d)),f=function(x){return Zo(tE(x),A)};c=function(x,w,y,v){u=y,f(x?x+"{"+w.styles+"}":w.styles),v&&(g.inserted[w.name]=!0)}}var g={key:r,sheet:new OC({key:r,container:s,nonce:t.nonce,speedy:t.speedy,prepend:t.prepend,insertionPoint:t.insertionPoint}),nonce:t.nonce,inserted:i,registered:{},insert:c};return g.sheet.hydrate(a),g}});var mE=X(pe=>{"use strict";var ct=typeof Symbol=="function"&&Symbol.for,Hm=ct?Symbol.for("react.element"):60103,Vm=ct?Symbol.for("react.portal"):60106,Qu=ct?Symbol.for("react.fragment"):60107,_u=ct?Symbol.for("react.strict_mode"):60108,ku=ct?Symbol.for("react.profiler"):60114,Du=ct?Symbol.for("react.provider"):60109,Nu=ct?Symbol.for("react.context"):60110,jm=ct?Symbol.for("react.async_mode"):60111,Lu=ct?Symbol.for("react.concurrent_mode"):60111,Fu=ct?Symbol.for("react.forward_ref"):60112,Pu=ct?Symbol.for("react.suspense"):60113,x5=ct?Symbol.for("react.suspense_list"):60120,Ou=ct?Symbol.for("react.memo"):60115,Gu=ct?Symbol.for("react.lazy"):60116,C5=ct?Symbol.for("react.block"):60121,E5=ct?Symbol.for("react.fundamental"):60117,b5=ct?Symbol.for("react.responder"):60118,w5=ct?Symbol.for("react.scope"):60119;function nr(e){if(typeof e=="object"&&e!==null){var t=e.$$typeof;switch(t){case Hm:switch(e=e.type,e){case jm:case Lu:case Qu:case ku:case _u:case Pu:return e;default:switch(e=e&&e.$$typeof,e){case Nu:case Fu:case Gu:case Ou:case Du:return e;default:return t}}case Vm:return t}}}function AE(e){return nr(e)===Lu}pe.AsyncMode=jm;pe.ConcurrentMode=Lu;pe.ContextConsumer=Nu;pe.ContextProvider=Du;pe.Element=Hm;pe.ForwardRef=Fu;pe.Fragment=Qu;pe.Lazy=Gu;pe.Memo=Ou;pe.Portal=Vm;pe.Profiler=ku;pe.StrictMode=_u;pe.Suspense=Pu;pe.isAsyncMode=function(e){return AE(e)||nr(e)===jm};pe.isConcurrentMode=AE;pe.isContextConsumer=function(e){return nr(e)===Nu};pe.isContextProvider=function(e){return nr(e)===Du};pe.isElement=function(e){return typeof e=="object"&&e!==null&&e.$$typeof===Hm};pe.isForwardRef=function(e){return nr(e)===Fu};pe.isFragment=function(e){return nr(e)===Qu};pe.isLazy=function(e){return nr(e)===Gu};pe.isMemo=function(e){return nr(e)===Ou};pe.isPortal=function(e){return nr(e)===Vm};pe.isProfiler=function(e){return nr(e)===ku};pe.isStrictMode=function(e){return nr(e)===_u};pe.isSuspense=function(e){return nr(e)===Pu};pe.isValidElementType=function(e){return typeof e=="string"||typeof e=="function"||e===Qu||e===Lu||e===ku||e===_u||e===Pu||e===x5||typeof e=="object"&&e!==null&&(e.$$typeof===Gu||e.$$typeof===Ou||e.$$typeof===Du||e.$$typeof===Nu||e.$$typeof===Fu||e.$$typeof===E5||e.$$typeof===b5||e.$$typeof===w5||e.$$typeof===C5)};pe.typeOf=nr});var gE=X((bq,pE)=>{"use strict";pE.exports=mE()});var wE=X((wq,bE)=>{"use strict";var $m=gE(),I5={childContextTypes:!0,contextType:!0,contextTypes:!0,defaultProps:!0,displayName:!0,getDefaultProps:!0,getDerivedStateFromError:!0,getDerivedStateFromProps:!0,mixins:!0,propTypes:!0,type:!0},S5={name:!0,length:!0,prototype:!0,caller:!0,callee:!0,arguments:!0,arity:!0},v5={$$typeof:!0,render:!0,defaultProps:!0,displayName:!0,propTypes:!0},CE={$$typeof:!0,compare:!0,defaultProps:!0,displayName:!0,propTypes:!0,type:!0},Wm={};Wm[$m.ForwardRef]=v5;Wm[$m.Memo]=CE;function hE(e){return $m.isMemo(e)?CE:Wm[e.$$typeof]||I5}var B5=Object.defineProperty,T5=Object.getOwnPropertyNames,yE=Object.getOwnPropertySymbols,M5=Object.getOwnPropertyDescriptor,R5=Object.getPrototypeOf,xE=Object.prototype;function EE(e,t,r){if(typeof t!="string"){if(xE){var n=R5(t);n&&n!==xE&&EE(e,n,r)}var o=T5(t);yE&&(o=o.concat(yE(t)));for(var i=hE(e),s=hE(t),a=0;a<o.length;++a){var c=o[a];if(!S5[c]&&!(r&&r[c])&&!(s&&s[c])&&!(i&&i[c])){var l=M5(t,c);try{B5(e,c,l)}catch{}}}}return e}bE.exports=EE});function ei(e,t,r){var n="";return r.split(" ").forEach(function(o){e[o]!==void 0?t.push(e[o]+";"):o&&(n+=o+" ")}),n}var Q5,Ss,ti,vs=m(()=>{Q5=!0;Ss=function(t,r,n){var o=t.key+"-"+r.name;(n===!1||Q5===!1)&&t.registered[o]===void 0&&(t.registered[o]=r.styles)},ti=function(t,r,n){Ss(t,r,n);var o=t.key+"-"+r.name;if(t.inserted[r.name]===void 0){var i=r;do t.insert(r===i?"."+o:"",i,t.sheet,!0),i=i.next;while(i!==void 0)}}});function IE(e){for(var t=0,r,n=0,o=e.length;o>=4;++n,o-=4)r=e.charCodeAt(n)&255|(e.charCodeAt(++n)&255)<<8|(e.charCodeAt(++n)&255)<<16|(e.charCodeAt(++n)&255)<<24,r=(r&65535)*1540483477+((r>>>16)*59797<<16),r^=r>>>24,t=(r&65535)*1540483477+((r>>>16)*59797<<16)^(t&65535)*1540483477+((t>>>16)*59797<<16);switch(o){case 3:t^=(e.charCodeAt(n+2)&255)<<16;case 2:t^=(e.charCodeAt(n+1)&255)<<8;case 1:t^=e.charCodeAt(n)&255,t=(t&65535)*1540483477+((t>>>16)*59797<<16)}return t^=t>>>13,t=(t&65535)*1540483477+((t>>>16)*59797<<16),((t^t>>>15)>>>0).toString(36)}var SE=m(()=>{});var vE,BE=m(()=>{vE={animationIterationCount:1,aspectRatio:1,borderImageOutset:1,borderImageSlice:1,borderImageWidth:1,boxFlex:1,boxFlexGroup:1,boxOrdinalGroup:1,columnCount:1,columns:1,flex:1,flexGrow:1,flexPositive:1,flexShrink:1,flexNegative:1,flexOrder:1,gridRow:1,gridRowEnd:1,gridRowSpan:1,gridRowStart:1,gridColumn:1,gridColumnEnd:1,gridColumnSpan:1,gridColumnStart:1,msGridRow:1,msGridRowSpan:1,msGridColumn:1,msGridColumnSpan:1,fontWeight:1,lineHeight:1,opacity:1,order:1,orphans:1,scale:1,tabSize:1,widows:1,zIndex:1,zoom:1,WebkitLineClamp:1,fillOpacity:1,floodOpacity:1,stopOpacity:1,strokeDasharray:1,strokeDashoffset:1,strokeMiterlimit:1,strokeOpacity:1,strokeWidth:1}});function fc(e,t,r){if(r==null)return"";var n=r;if(n.__emotion_styles!==void 0)return n;switch(typeof r){case"boolean":return"";case"object":{var o=r;if(o.anim===1)return un={name:o.name,styles:o.styles,next:un},o.name;var i=r;if(i.styles!==void 0){var s=i.next;if(s!==void 0)for(;s!==void 0;)un={name:s.name,styles:s.styles,next:un},s=s.next;var a=i.styles+";";return a}return L5(e,t,r)}case"function":{if(e!==void 0){var c=un,l=r(e);return un=c,fc(e,t,l)}break}}var u=r;if(t==null)return u;var d=t[u];return d!==void 0?d:u}function L5(e,t,r){var n="";if(Array.isArray(r))for(var o=0;o<r.length;o++)n+=fc(e,t,r[o])+";";else for(var i in r){var s=r[i];if(typeof s!="object"){var a=s;t!=null&&t[a]!==void 0?n+=i+"{"+t[a]+"}":TE(a)&&(n+=Ym(i)+":"+ME(i,a)+";")}else{if(i==="NO_COMPONENT_SELECTOR"&&_5)throw new Error(N5);if(Array.isArray(s)&&typeof s[0]=="string"&&(t==null||t[s[0]]===void 0))for(var c=0;c<s.length;c++)TE(s[c])&&(n+=Ym(i)+":"+ME(i,s[c])+";");else{var l=fc(e,t,s);switch(i){case"animation":case"animationName":{n+=Ym(i)+":"+l+";";break}default:n+=i+"{"+l+"}"}}}}return n}function fn(e,t,r){if(e.length===1&&typeof e[0]=="object"&&e[0]!==null&&e[0].styles!==void 0)return e[0];var n=!0,o="";un=void 0;var i=e[0];if(i==null||i.raw===void 0)n=!1,o+=fc(r,t,i);else{var s=i;o+=s[0]}for(var a=1;a<e.length;a++)if(o+=fc(r,t,e[a]),n){var c=i;o+=c[a]}RE.lastIndex=0;for(var l="",u;(u=RE.exec(o))!==null;)l+="-"+u[1];var d=IE(o)+l;return{name:d,styles:o,next:un}}var _5,k5,D5,QE,TE,Ym,ME,N5,RE,un,ri=m(()=>{SE();BE();Ru();_5=!1,k5=/[A-Z]|^ms/g,D5=/_EMO_([^_]+?)_([^]*?)_EMO_/g,QE=function(t){return t.charCodeAt(1)===45},TE=function(t){return t!=null&&typeof t!="boolean"},Ym=Mu(function(e){return QE(e)?e:e.replace(k5,"-$&").toLowerCase()}),ME=function(t,r){switch(t){case"animation":case"animationName":if(typeof r=="string")return r.replace(D5,function(n,o,i){return un={name:o,styles:i,next:un},o})}return vE[t]!==1&&!QE(t)&&typeof r=="number"&&r!==0?r+"px":r},N5="Component selectors can only be used in conjunction with @emotion/babel-plugin, the swc Emotion plugin, or another Emotion-aware compiler transform.";RE=/label:\s*([^\s;{]+)\s*(;|$)/g});var Uu,F5,P5,dc,Ac=m(()=>{Uu=p(Q()),F5=function(t){return t()},P5=Uu.useInsertionEffect?Uu.useInsertionEffect:!1,dc=P5||F5});var xr,mc,_E,zm,O5,Jm,pc,Ao,Hu,qm,kE,G5,U5,DE,Km=m(()=>{xr=p(Q()),mc=p(Q());Um();sc();Tu();vs();ri();Ac();_E=!1,zm=xr.createContext(typeof HTMLElement<"u"?dE({key:"css"}):null),O5=zm.Provider,Jm=function(){return(0,mc.useContext)(zm)},pc=function(t){return(0,mc.forwardRef)(function(r,n){var o=(0,mc.useContext)(zm);return t(r,o,n)})},Ao=xr.createContext({}),Hu={}.hasOwnProperty,qm="__EMOTION_TYPE_PLEASE_DO_NOT_USE__",kE=function(t,r){var n={};for(var o in r)Hu.call(r,o)&&(n[o]=r[o]);return n[qm]=t,n},G5=function(t){var r=t.cache,n=t.serialized,o=t.isStringTag;return Ss(r,n,o),dc(function(){return ti(r,n,o)}),null},U5=pc(function(e,t,r){var n=e.css;typeof n=="string"&&t.registered[n]!==void 0&&(n=t.registered[n]);var o=e[qm],i=[n],s="";typeof e.className=="string"?s=ei(t.registered,i,e.className):e.className!=null&&(s=e.className+" ");var a=fn(i,void 0,xr.useContext(Ao));s+=t.key+"-"+a.name;var c={};for(var l in e)Hu.call(e,l)&&l!=="css"&&l!==qm&&!_E&&(c[l]=e[l]);return c.className=s,r&&(c.ref=r),xr.createElement(xr.Fragment,null,xr.createElement(G5,{cache:t,serialized:a,isStringTag:typeof o=="string"}),xr.createElement(o,c))}),DE=U5});function LE(){for(var e=arguments.length,t=new Array(e),r=0;r<e;r++)t[r]=arguments[r];return fn(t)}function Vu(){var e=LE.apply(void 0,arguments),t="animation-"+e.name;return{name:t,styles:"@keyframes "+t+"{"+e.styles+"}",anim:1,toString:function(){return"_EMO_"+this.name+"_"+this.styles+"_EMO_"}}}var Bs,Kq,NE,gc=m(()=>{Km();Km();Bs=p(Q());vs();Ac();ri();Um();sc();Tu();Kq=p(wE()),NE=function(t,r){var n=arguments;if(r==null||!Hu.call(r,"css"))return Bs.createElement.apply(void 0,n);var o=n.length,i=new Array(o);i[0]=DE,i[1]=kE(t,r);for(var s=2;s<o;s++)i[s]=n[s];return Bs.createElement.apply(null,i)};(function(e){var t;t||(t=e.JSX||(e.JSX={}))})(NE||(NE={}))});var H5,FE,Xm=m(()=>{Ru();H5=/^((children|dangerouslySetInnerHTML|key|ref|autoFocus|defaultValue|defaultChecked|innerHTML|suppressContentEditableWarning|suppressHydrationWarning|valueLink|abbr|accept|acceptCharset|accessKey|action|allow|allowUserMedia|allowPaymentRequest|allowFullScreen|allowTransparency|alt|async|autoComplete|autoPlay|capture|cellPadding|cellSpacing|challenge|charSet|checked|cite|classID|className|cols|colSpan|content|contentEditable|contextMenu|controls|controlsList|coords|crossOrigin|data|dateTime|decoding|default|defer|dir|disabled|disablePictureInPicture|disableRemotePlayback|download|draggable|encType|enterKeyHint|fetchpriority|fetchPriority|form|formAction|formEncType|formMethod|formNoValidate|formTarget|frameBorder|headers|height|hidden|high|href|hrefLang|htmlFor|httpEquiv|id|inputMode|integrity|is|keyParams|keyType|kind|label|lang|list|loading|loop|low|marginHeight|marginWidth|max|maxLength|media|mediaGroup|method|min|minLength|multiple|muted|name|nonce|noValidate|open|optimum|pattern|placeholder|playsInline|popover|popoverTarget|popoverTargetAction|poster|preload|profile|radioGroup|readOnly|referrerPolicy|rel|required|reversed|role|rows|rowSpan|sandbox|scope|scoped|scrolling|seamless|selected|shape|size|sizes|slot|span|spellCheck|src|srcDoc|srcLang|srcSet|start|step|style|summary|tabIndex|target|title|translate|type|useMap|value|width|wmode|wrap|about|datatype|inlist|prefix|property|resource|typeof|vocab|autoCapitalize|autoCorrect|autoSave|color|incremental|fallback|inert|itemProp|itemScope|itemType|itemID|itemRef|on|option|results|security|unselectable|accentHeight|accumulate|additive|alignmentBaseline|allowReorder|alphabetic|amplitude|arabicForm|ascent|attributeName|attributeType|autoReverse|azimuth|baseFrequency|baselineShift|baseProfile|bbox|begin|bias|by|calcMode|capHeight|clip|clipPathUnits|clipPath|clipRule|colorInterpolation|colorInterpolationFilters|colorProfile|colorRendering|contentScriptType|contentStyleType|cursor|cx|cy|d|decelerate|descent|diffuseConstant|direction|display|divisor|dominantBaseline|dur|dx|dy|edgeMode|elevation|enableBackground|end|exponent|externalResourcesRequired|fill|fillOpacity|fillRule|filter|filterRes|filterUnits|floodColor|floodOpacity|focusable|fontFamily|fontSize|fontSizeAdjust|fontStretch|fontStyle|fontVariant|fontWeight|format|from|fr|fx|fy|g1|g2|glyphName|glyphOrientationHorizontal|glyphOrientationVertical|glyphRef|gradientTransform|gradientUnits|hanging|horizAdvX|horizOriginX|ideographic|imageRendering|in|in2|intercept|k|k1|k2|k3|k4|kernelMatrix|kernelUnitLength|kerning|keyPoints|keySplines|keyTimes|lengthAdjust|letterSpacing|lightingColor|limitingConeAngle|local|markerEnd|markerMid|markerStart|markerHeight|markerUnits|markerWidth|mask|maskContentUnits|maskUnits|mathematical|mode|numOctaves|offset|opacity|operator|order|orient|orientation|origin|overflow|overlinePosition|overlineThickness|panose1|paintOrder|pathLength|patternContentUnits|patternTransform|patternUnits|pointerEvents|points|pointsAtX|pointsAtY|pointsAtZ|preserveAlpha|preserveAspectRatio|primitiveUnits|r|radius|refX|refY|renderingIntent|repeatCount|repeatDur|requiredExtensions|requiredFeatures|restart|result|rotate|rx|ry|scale|seed|shapeRendering|slope|spacing|specularConstant|specularExponent|speed|spreadMethod|startOffset|stdDeviation|stemh|stemv|stitchTiles|stopColor|stopOpacity|strikethroughPosition|strikethroughThickness|string|stroke|strokeDasharray|strokeDashoffset|strokeLinecap|strokeLinejoin|strokeMiterlimit|strokeOpacity|strokeWidth|surfaceScale|systemLanguage|tableValues|targetX|targetY|textAnchor|textDecoration|textRendering|textLength|to|transform|u1|u2|underlinePosition|underlineThickness|unicode|unicodeBidi|unicodeRange|unitsPerEm|vAlphabetic|vHanging|vIdeographic|vMathematical|values|vectorEffect|version|vertAdvY|vertOriginX|vertOriginY|viewBox|viewTarget|visibility|widths|wordSpacing|writingMode|x|xHeight|x1|x2|xChannelSelector|xlinkActuate|xlinkArcrole|xlinkHref|xlinkRole|xlinkShow|xlinkTitle|xlinkType|xmlBase|xmlns|xmlnsXlink|xmlLang|xmlSpace|y|y1|y2|yChannelSelector|z|zoomAndPan|for|class|autofocus)|(([Dd][Aa][Tt][Aa]|[Aa][Rr][Ii][Aa]|x)-.*))$/,FE=Mu(function(e){return H5.test(e)||e.charCodeAt(0)===111&&e.charCodeAt(1)===110&&e.charCodeAt(2)<91})});var mo,V5,j5,$5,PE,OE,W5,GE,UE=m(()=>{sc();gc();ri();Ac();vs();mo=p(Q());Xm();V5=!1,j5=FE,$5=function(t){return t!=="theme"},PE=function(t){return typeof t=="string"&&t.charCodeAt(0)>96?j5:$5},OE=function(t,r,n){var o;if(r){var i=r.shouldForwardProp;o=t.__emotion_forwardProp&&i?function(s){return t.__emotion_forwardProp(s)&&i(s)}:i}return typeof o!="function"&&n&&(o=t.__emotion_forwardProp),o},W5=function(t){var r=t.cache,n=t.serialized,o=t.isStringTag;return Ss(r,n,o),dc(function(){return ti(r,n,o)}),null},GE=function e(t,r){var n=t.__emotion_real===t,o=n&&t.__emotion_base||t,i,s;r!==void 0&&(i=r.label,s=r.target);var a=OE(t,r,n),c=a||PE(o),l=!c("as");return function(){var u=arguments,d=n&&t.__emotion_styles!==void 0?t.__emotion_styles.slice(0):[];if(i!==void 0&&d.push("label:"+i+";"),u[0]==null||u[0].raw===void 0)d.push.apply(d,u);else{var A=u[0];d.push(A[0]);for(var f=u.length,g=1;g<f;g++)d.push(u[g],A[g])}var h=pc(function(x,w,y){var v=l&&x.as||o,b="",I=[],S=x;if(x.theme==null){S={};for(var B in x)S[B]=x[B];S.theme=mo.useContext(Ao)}typeof x.className=="string"?b=ei(w.registered,I,x.className):x.className!=null&&(b=x.className+" ");var R=fn(d.concat(I),w.registered,S);b+=w.key+"-"+R.name,s!==void 0&&(b+=" "+s);var D=l&&a===void 0?PE(v):c,L={};for(var P in x)l&&P==="as"||D(P)&&(L[P]=x[P]);return L.className=b,y&&(L.ref=y),mo.createElement(mo.Fragment,null,mo.createElement(W5,{cache:w,serialized:R,isStringTag:typeof v=="string"}),mo.createElement(v,L))});return h.displayName=i!==void 0?i:"Styled("+(typeof o=="string"?o:o.displayName||o.name||"Component")+")",h.defaultProps=t.defaultProps,h.__emotion_real=h,h.__emotion_base=o,h.__emotion_styles=d,h.__emotion_forwardProp=a,Object.defineProperty(h,"toString",{value:function(){return s===void 0&&V5?"NO_COMPONENT_SELECTOR":"."+s}}),h.withComponent=function(x,w){var y=e(x,ic({},r,w,{shouldForwardProp:OE(h,w,!0)}));return y.apply(void 0,d)},h}}});var mz,Y5,ju,HE=m(()=>{UE();sc();ri();Ac();vs();mz=p(Q());Xm();Y5=["a","abbr","address","area","article","aside","audio","b","base","bdi","bdo","big","blockquote","body","br","button","canvas","caption","cite","code","col","colgroup","data","datalist","dd","del","details","dfn","dialog","div","dl","dt","em","embed","fieldset","figcaption","figure","footer","form","h1","h2","h3","h4","h5","h6","head","header","hgroup","hr","html","i","iframe","img","input","ins","kbd","keygen","label","legend","li","link","main","map","mark","marquee","menu","menuitem","meta","meter","nav","noscript","object","ol","optgroup","option","output","p","param","picture","pre","progress","q","rp","rt","ruby","s","samp","script","section","select","small","source","span","strong","style","sub","summary","sup","table","tbody","td","textarea","tfoot","th","thead","time","title","tr","track","u","ul","var","video","wbr","circle","clipPath","defs","ellipse","foreignObject","g","image","line","linearGradient","mask","path","pattern","polygon","polyline","radialGradient","rect","stop","svg","text","tspan"],ju=GE.bind(null);Y5.forEach(function(e){ju[e]=ju(e)})});var O=X((hz,VE)=>{VE.exports=JBrowseExports["react/jsx-runtime"]});function q5(e,t){return ju(e,t)}function $E(e,t){Array.isArray(e.__emotion_styles)&&(e.__emotion_styles=t(e.__emotion_styles))}function On(e){return jE[0]=e,fn(jE)}var $u,jE,hc=m(()=>{"use client";HE();ri();gc();$u=q5;jE=[]});var z5,WE,YE=m(()=>{z5={borderRadius:4},WE=z5});function Ts(e=8,t=Za({spacing:e})){if(e.mui)return e;let r=(...n)=>(n.length===0?[1]:n).map(i=>{let s=t(i);return typeof s=="number"?`${s}px`:s}).join(" ");return r.mui=!0,r}var Zm=m(()=>{Jo()});function ep(e,t){let r=this;if(r.vars){if(!r.colorSchemes?.[e]||typeof r.getColorSchemeSelector!="function")return{};let n=r.getColorSchemeSelector(e);return n==="&"?t:((n.includes("data-")||n.includes("."))&&(n=`*:where(${n.replace(/\s*&$/,"")}) &`),{[n]:t})}return r.palette.mode===e?t:{}}var qE=m(()=>{});function J5(e={},...t){let{breakpoints:r={},palette:n={},spacing:o,shape:i={},...s}=e,a=za(r),c=Ts(o),l=Je({breakpoints:a,direction:"ltr",components:{},palette:{mode:"light",...n},spacing:c,shape:{...WE,...i}},s);return l=pu(l),l.applyStyles=ep,l=t.reduce((u,d)=>Je(u,d),l),l.unstable_sxConfig={...Pn,...s?.unstable_sxConfig},l.unstable_sx=function(d){return hr({sx:d,theme:this})},l.internal_cache={},l}var ni,zE=m(()=>{Fn();bm();gu();YE();Zm();Lm();xu();qE();ni=J5});var Wu=m(()=>{zE()});function K5(e){return Object.keys(e).length===0}function X5(e=null){let t=JE.useContext(Ao);return!t||K5(t)?e:t}var JE,tp,KE=m(()=>{"use client";JE=p(Q(),1);hc();tp=X5});var XE=m(()=>{KE()});function e3(e=Z5){return tp(e)}var Z5,rp,np=m(()=>{"use client";Wu();XE();Z5=ni();rp=e3});var ZE=m(()=>{np();np()});var t3,r3,n3,o3,i3,s3,a3,c3,l3,u3,f3,d3,A3,zz,eb=m(()=>{ln();uo();t3=$({prop:"flexBasis"}),r3=$({prop:"flexDirection"}),n3=$({prop:"flexWrap"}),o3=$({prop:"justifyContent"}),i3=$({prop:"alignItems"}),s3=$({prop:"alignContent"}),a3=$({prop:"order"}),c3=$({prop:"flex"}),l3=$({prop:"flexGrow"}),u3=$({prop:"flexShrink"}),f3=$({prop:"alignSelf"}),d3=$({prop:"justifyItems"}),A3=$({prop:"justifySelf"}),zz=Ft(t3,r3,n3,o3,i3,s3,a3,c3,l3,u3,f3,d3,A3)});var tb=m(()=>{eb()});var m3,p3,g3,h3,y3,x3,tJ,rb=m(()=>{ln();uo();m3=$({prop:"position"}),p3=$({prop:"zIndex",themeKey:"zIndex"}),g3=$({prop:"top"}),h3=$({prop:"right"}),y3=$({prop:"bottom"}),x3=$({prop:"left"}),tJ=Ft(m3,p3,g3,h3,y3,x3)});var nb=m(()=>{rb()});var C3,E3,b3,w3,I3,S3,v3,B3,T3,aJ,ob=m(()=>{ln();uo();C3=$({prop:"fontFamily",themeKey:"typography"}),E3=$({prop:"fontSize",themeKey:"typography"}),b3=$({prop:"fontStyle",themeKey:"typography"}),w3=$({prop:"fontWeight",themeKey:"typography"}),I3=$({prop:"letterSpacing"}),S3=$({prop:"textTransform"}),v3=$({prop:"lineHeight"}),B3=$({prop:"textAlign"}),T3=$({prop:"typography",cssProperty:!1,themeKey:"typography"}),aJ=Ft(T3,C3,E3,b3,w3,I3,v3,B3,S3)});var ib=m(()=>{ob()});var sb,M3,R3,yc,ab=m(()=>{sb=e=>e,M3=()=>{let e=sb;return{configure(t){e=t},generate(t){return e(t)},reset(){e=sb}}},R3=M3(),yc=R3});var op=m(()=>{ab()});function Yu(e={}){let{themeId:t,defaultTheme:r,defaultClassName:n="MuiBox-root",generateClassName:o}=e,i=$u("div",{shouldForwardProp:a=>a!=="theme"&&a!=="sx"&&a!=="as"})(hr);return cb.forwardRef(function(c,l){let u=rp(r),{className:d,component:A="div",...f}=c;return(0,lb.jsx)(i,{as:A,ref:l,className:as(d,o?o(n):n),theme:t&&u[t]||u,...f})})}var cb,lb,ub=m(()=>{"use client";cb=p(Q(),1);eu();hc();oc();ZE();lb=p(O(),1)});var fb=m(()=>{ub()});function Ms(e,t,r="Mui"){let n=Q3[t];return n?`${r}-${n}`:`${yc.generate(e)}-${t}`}var Q3,ip=m(()=>{op();Q3={active:"active",checked:"checked",completed:"completed",disabled:"disabled",error:"error",expanded:"expanded",focused:"focused",focusVisible:"focusVisible",open:"open",readOnly:"readOnly",required:"required",selected:"selected"}});var sp=m(()=>{ip();ip()});function Cr(e,t,r="Mui"){let n={};return t.forEach(o=>{n[o]=Ms(e,o,r)}),n}var db=m(()=>{sp()});var Rs=m(()=>{db()});var _3,Ab,ap=m(()=>{Rs();_3=Cr("MuiBox",["root"]),Ab=_3});var NJ,mb=m(()=>{"use client";op();fb();ap();NJ=Yu({defaultClassName:Ab.root,generateClassName:yc.generate})});var pb=m(()=>{mb();ap()});function xc(e){let{variants:t,...r}=e,n={variants:t,style:On(r),isProcessed:!0};return n.style===r||t&&t.forEach(o=>{typeof o.style!="function"&&(o.style=On(o.style))}),n}var cp=m(()=>{hc()});function lp(e){return e!=="ownerState"&&e!=="theme"&&e!=="sx"&&e!=="as"}function oi(e,t){return t&&e&&typeof e=="object"&&e.styles&&!e.styles.startsWith("@layer")&&(e.styles=`@layer ${t}{${String(e.styles)}}`),e}function D3(e){return e?(t,r)=>r[e]:null}function N3(e,t,r){e.theme=fs(e.theme)?r:e.theme[t]||e.theme}function qu(e,t,r){let n=typeof t=="function"?t(e):t;if(Array.isArray(n))return n.flatMap(o=>qu(e,o,r));if(Array.isArray(n?.variants)){let o;if(n.isProcessed)o=r?oi(n.style,r):n.style;else{let{variants:i,...s}=n;o=r?oi(On(s),r):s}return gb(e,n.variants,[o],r)}return n?.isProcessed?r?oi(On(n.style),r):n.style:r?oi(On(n),r):n}function gb(e,t,r=[],n=void 0){let o;e:for(let i=0;i<t.length;i+=1){let s=t[i];if(typeof s.props=="function"){if(o??={...e,...e.ownerState,ownerState:e.ownerState},!s.props(o))continue}else for(let a in s.props)if(e[a]!==s.props[a]&&e.ownerState?.[a]!==s.props[a])continue e;typeof s.style=="function"?(o??={...e,...e.ownerState,ownerState:e.ownerState},r.push(n?oi(On(s.style(o)),n):s.style(o))):r.push(n?oi(On(s.style),n):s.style)}return r}function zu(e={}){let{themeId:t,defaultTheme:r=k3,rootShouldForwardProp:n=lp,slotShouldForwardProp:o=lp}=e;function i(a){N3(a,t,r)}return(a,c={})=>{$E(a,S=>S.filter(B=>B!==hr));let{name:l,slot:u,skipVariantsResolver:d,skipSx:A,overridesResolver:f=D3(P3(u)),...g}=c,h=l&&l.startsWith("Mui")||u?"components":"custom",x=d!==void 0?d:u&&u!=="Root"&&u!=="root"||!1,w=A||!1,y=lp;u==="Root"||u==="root"?y=n:u?y=o:F3(a)&&(y=void 0);let v=$u(a,{shouldForwardProp:y,label:L3(l,u),...g}),b=S=>{if(S.__emotion_real===S)return S;if(typeof S=="function")return function(R){return qu(R,S,R.theme.modularCssLayers?h:void 0)};if(Pr(S)){let B=xc(S);return function(D){return B.variants?qu(D,B,D.theme.modularCssLayers?h:void 0):D.theme.modularCssLayers?oi(B.style,h):B.style}}return S},I=(...S)=>{let B=[],R=S.map(b),D=[];if(B.push(i),l&&f&&D.push(function(M){let G=M.theme.components?.[l]?.styleOverrides;if(!G)return null;let j={};for(let oe in G)j[oe]=qu(M,G[oe],M.theme.modularCssLayers?"theme":void 0);return f(M,j)}),l&&!x&&D.push(function(M){let G=M.theme?.components?.[l]?.variants;return G?gb(M,G,[],M.theme.modularCssLayers?"theme":void 0):null}),w||D.push(hr),Array.isArray(R[0])){let C=R.shift(),M=new Array(B.length).fill(""),k=new Array(D.length).fill(""),G;G=[...M,...C,...k],G.raw=[...M,...C.raw,...k],B.unshift(G)}let L=[...B,...R,...D],P=v(...L);return a.muiName&&(P.muiName=a.muiName),P};return v.withConfig&&(I.withConfig=v.withConfig),I}}function L3(e,t){return void 0}function F3(e){return typeof e=="string"&&e.charCodeAt(0)>96}function P3(e){return e&&e.charAt(0).toLowerCase()+e.slice(1)}var k3,up=m(()=>{hc();mm();Fn();Wu();oc();cp();k3=ni()});var fp=m(()=>{up();up()});function Qs(e,t,r=!1){let n={...t};for(let o in e)if(Object.prototype.hasOwnProperty.call(e,o)){let i=o;if(i==="components"||i==="slots")n[i]={...e[i],...n[i]};else if(i==="componentsProps"||i==="slotProps"){let s=e[i],a=t[i];if(!a)n[i]=s||{};else if(!s)n[i]=a;else{n[i]={...a};for(let c in s)if(Object.prototype.hasOwnProperty.call(s,c)){let l=c;n[i][l]=Qs(s[l],a[l],r)}}}else i==="className"&&r&&t.className!==void 0?n.className=as(e?.className,t?.className):i==="style"&&r&&t.style?n.style={...e?.style,...t?.style}:n[i]===void 0&&(n[i]=e[i])}return n}var hb=m(()=>{eu()});var yb=m(()=>{hb()});function O3(e,t=Number.MIN_SAFE_INTEGER,r=Number.MAX_SAFE_INTEGER){return Math.max(t,Math.min(e,r))}var dp,xb=m(()=>{dp=O3});var Cb=m(()=>{xb()});function mp(e,t=0,r=1){return dp(e,t,r)}function G3(e){e=e.slice(1);let t=new RegExp(`.{1,${e.length>=6?2:1}}`,"g"),r=e.match(t);return r&&r[0].length===1&&(r=r.map(n=>n+n)),r?`rgb${r.length===4?"a":""}(${r.map((n,o)=>o<3?parseInt(n,16):Math.round(parseInt(n,16)/255*1e3)/1e3).join(", ")})`:""}function po(e){if(e.type)return e;if(e.charAt(0)==="#")return po(G3(e));let t=e.indexOf("("),r=e.substring(0,t);if(!["rgb","rgba","hsl","hsla","color"].includes(r))throw new Error(Jt(9,e));let n=e.substring(t+1,e.length-1),o;if(r==="color"){if(n=n.split(" "),o=n.shift(),n.length===4&&n[3].charAt(0)==="/"&&(n[3]=n[3].slice(1)),!["srgb","display-p3","a98-rgb","prophoto-rgb","rec-2020"].includes(o))throw new Error(Jt(10,o))}else n=n.split(",");return n=n.map(i=>parseFloat(i)),{type:r,values:n,colorSpace:o}}function Ju(e){let{type:t,colorSpace:r}=e,{values:n}=e;return t.includes("rgb")?n=n.map((o,i)=>i<3?parseInt(o,10):o):t.includes("hsl")&&(n[1]=`${n[1]}%`,n[2]=`${n[2]}%`),t.includes("color")?n=`${r} ${n.join(" ")}`:n=`${n.join(", ")}`,`${t}(${n})`}function pp(e){e=po(e);let{values:t}=e,r=t[0],n=t[1]/100,o=t[2]/100,i=n*Math.min(o,1-o),s=(l,u=(l+r/30)%12)=>o-i*Math.max(Math.min(u-3,9-u,1),-1),a="rgb",c=[Math.round(s(0)*255),Math.round(s(8)*255),Math.round(s(4)*255)];return e.type==="hsla"&&(a+="a",c.push(t[3])),Ju({type:a,values:c})}function Ap(e){e=po(e);let t=e.type==="hsl"||e.type==="hsla"?po(pp(e)).values:e.values;return t=t.map(r=>(e.type!=="color"&&(r/=255),r<=.03928?r/12.92:((r+.055)/1.055)**2.4)),Number((.2126*t[0]+.7152*t[1]+.0722*t[2]).toFixed(3))}function Eb(e,t){let r=Ap(e),n=Ap(t);return(Math.max(r,n)+.05)/(Math.min(r,n)+.05)}function gp(e,t){return e=po(e),t=mp(t),(e.type==="rgb"||e.type==="hsl")&&(e.type+="a"),e.type==="color"?e.values[3]=`/${t}`:e.values[3]=t,Ju(e)}function go(e,t,r){try{return gp(e,t)}catch{return e}}function ks(e,t){if(e=po(e),t=mp(t),e.type.includes("hsl"))e.values[2]*=1-t;else if(e.type.includes("rgb")||e.type.includes("color"))for(let r=0;r<3;r+=1)e.values[r]*=1-t;return Ju(e)}function ce(e,t,r){try{return ks(e,t)}catch{return e}}function Ds(e,t){if(e=po(e),t=mp(t),e.type.includes("hsl"))e.values[2]+=(100-e.values[2])*t;else if(e.type.includes("rgb"))for(let r=0;r<3;r+=1)e.values[r]+=(255-e.values[r])*t;else if(e.type.includes("color"))for(let r=0;r<3;r+=1)e.values[r]+=(1-e.values[r])*t;return Ju(e)}function le(e,t,r){try{return Ds(e,t)}catch{return e}}function H3(e,t=.15){return Ap(e)>.5?ks(e,t):Ds(e,t)}function Cc(e,t,r){try{return H3(e,t)}catch{return e}}var U3,_s,bb=m(()=>{cs();Cb();U3=e=>{let t=po(e);return t.values.slice(0,3).map((r,n)=>t.type.includes("hsl")&&n!==0?`${r}%`:r).join(" ")},_s=(e,t)=>{try{return U3(e)}catch{return e}}});var Ec=m(()=>{bb()});var wb,V3,Ib=m(()=>{"use client";wb=p(Q(),1),V3=p(O(),1)});function W3(e){let{theme:t,name:r,props:n}=e;if(!t||!t.components||!t.components[r])return n;let o=t.components[r];return o.defaultProps?Qs(o.defaultProps,n,t.components.mergeClassNameAndStyle):!o.styleOverrides&&!o.variants?Qs(o,n,t.components.mergeClassNameAndStyle):n}function hp({props:e,name:t}){let r=Ku.useContext($3);return W3({props:e,name:t,theme:{components:r}})}var Ku,j3,$3,Sb=m(()=>{"use client";Ku=p(Q(),1);yb();j3=p(O(),1),$3=Ku.createContext(void 0)});var vb=m(()=>{Sb()});function Xu(e){let t,r;return function(o){let i=t;return(i===void 0||o.theme!==r)&&(Bb.theme=o.theme,i=xc(e(Bb)),t=i,r=o.theme),i}}var Bb,Tb=m(()=>{cp();Bb={theme:void 0}});function Zu(e=""){function t(...n){if(!n.length)return"";let o=n[0];return typeof o=="string"&&!o.match(/(#|\(|\)|(-?(\d*\.)?\d+)(px|em|%|ex|ch|rem|vw|vh|vmin|vmax|cm|mm|in|pt|pc))|^(-?(\d*\.)?\d+)$|(\d+ \d+ \d+)/)?`, var(--${e?`${e}-`:""}${o}${t(...n.slice(1))})`:`, ${o}`}return(n,...o)=>`var(--${e?`${e}-`:""}${n}${t(...o)})`}var Mb=m(()=>{});function bc(e,t){let{prefix:r,shouldSkipGeneratingVar:n}=t||{},o={},i={},s={};return q3(e,(a,c,l)=>{if((typeof c=="string"||typeof c=="number")&&(!n||!n(a,c))){let u=`--${r?`${r}-`:""}${a.join("-")}`,d=z3(a,c);Object.assign(o,{[u]:d}),Rb(i,a,`var(${u})`,l),Rb(s,a,`var(${u}, ${d})`,l)}},a=>a[0]==="vars"),{css:o,vars:i,varsWithDefaults:s}}var Rb,q3,z3,Qb=m(()=>{Rb=(e,t,r,n=[])=>{let o=e;t.forEach((i,s)=>{s===t.length-1?Array.isArray(o)?o[Number(i)]=r:o&&typeof o=="object"&&(o[i]=r):o&&typeof o=="object"&&(o[i]||(o[i]=n.includes(i)?[]:{}),o=o[i])})},q3=(e,t,r)=>{function n(o,i=[],s=[]){Object.entries(o).forEach(([a,c])=>{(!r||r&&!r([...i,a]))&&c!=null&&(typeof c=="object"&&Object.keys(c).length>0?n(c,[...i,a],Array.isArray(c)?[...s,a]:s):t([...i,a],c,s))})}n(e)},z3=(e,t)=>typeof t=="number"?["lineHeight","fontWeight","opacity","zIndex"].some(n=>e.includes(n))||e[e.length-1].toLowerCase().includes("opacity")?t:`${t}px`:t});function J3(e,t={}){let{getSelector:r=w,disableCssColorScheme:n,colorSchemeSelector:o,enableContrastVars:i}=t,{colorSchemes:s={},components:a,defaultColorScheme:c="light",...l}=e,{vars:u,css:d,varsWithDefaults:A}=bc(l,t),f=A,g={},{[c]:h,...x}=s;if(Object.entries(x||{}).forEach(([b,I])=>{let{vars:S,css:B,varsWithDefaults:R}=bc(I,t);f=Je(f,R),g[b]={css:B,vars:S}}),h){let{css:b,vars:I,varsWithDefaults:S}=bc(h,t);f=Je(f,S),g[c]={css:b,vars:I}}function w(b,I){let S=o;if(o==="class"&&(S=".%s"),o==="data"&&(S="[data-%s]"),o?.startsWith("data-")&&!o.includes("%s")&&(S=`[${o}="%s"]`),b){if(S==="media")return e.defaultColorScheme===b?":root":{[`@media (prefers-color-scheme: ${s[b]?.palette?.mode||b})`]:{":root":I}};if(S)return e.defaultColorScheme===b?`:root, ${S.replace("%s",String(b))}`:S.replace("%s",String(b))}return":root"}return{vars:f,generateThemeVars:()=>{let b={...u};return Object.entries(g).forEach(([,{vars:I}])=>{b=Je(b,I)}),b},generateStyleSheets:()=>{let b=[],I=e.defaultColorScheme||"light";function S(D,L){Object.keys(L).length&&b.push(typeof D=="string"?{[D]:{...L}}:D)}S(r(void 0,{...d}),d);let{[I]:B,...R}=g;if(B){let{css:D}=B,L=s[I]?.palette?.mode,P=!n&&L?{colorScheme:L,...D}:{...D};S(r(I,{...P}),P)}return Object.entries(R).forEach(([D,{css:L}])=>{let P=s[D]?.palette?.mode,C=!n&&P?{colorScheme:P,...L}:{...L};S(r(D,{...C}),C)}),i&&b.push({":root":{"--__l-threshold":"0.7","--__l":"clamp(0, (l / var(--__l-threshold) - 1) * -infinity, 1)","--__a":"clamp(0.87, (l / var(--__l-threshold) - 1) * -infinity, 1)"}}),b}}}var yp,_b=m(()=>{Fn();Qb();yp=J3});function xp(e){return function(r){return e==="media"?`@media (prefers-color-scheme: ${r})`:e?e.startsWith("data-")&&!e.includes("%s")?`[${e}="${r}"] &`:e==="class"?`.${r} &`:e==="data"?`[data-${r}] &`:`${e.replace("%s",r)} &`:"&"}}var kb=m(()=>{});var Db=m(()=>{});var SK,Nb=m(()=>{Rs();SK=Cr("MuiContainer",["root","disableGutters","fixed","maxWidthXs","maxWidthSm","maxWidthMd","maxWidthLg","maxWidthXl"])});var Lb=m(()=>{Nb()});var Fb=m(()=>{});var K3,X3,Z3,wc,RK,Pb=m(()=>{Rs();K3=[0,1,2,3,4,5,6,7,8,9,10],X3=["column-reverse","column","row-reverse","row"],Z3=["nowrap","wrap-reverse","wrap"],wc=["auto","grow",1,2,3,4,5,6,7,8,9,10,11,12],RK=Cr("MuiGrid",["root","container","item",...K3.map(e=>`spacing-xs-${e}`),...X3.map(e=>`direction-xs-${e}`),...Z3.map(e=>`wrap-xs-${e}`),...wc.map(e=>`grid-xs-${e}`),...wc.map(e=>`grid-sm-${e}`),...wc.map(e=>`grid-md-${e}`),...wc.map(e=>`grid-lg-${e}`),...wc.map(e=>`grid-xl-${e}`)])});var Ob=m(()=>{Fb();Pb()});var Gb=m(()=>{});var LK,Ub=m(()=>{Rs();LK=Cr("MuiStack",["root"])});var Hb=m(()=>{Gb();Ub()});var Cp=m(()=>{_m();tb();km();Dm();nb();Nm();Jo();ib();pb();fp();Zm();Ec();Tb();Mb();Ib();Db();Lb();Ob();Hb();});var e4,Ns,Vb=m(()=>{e4={black:"#000",white:"#fff"},Ns=e4});var t4,jb,$b=m(()=>{t4={50:"#fafafa",100:"#f5f5f5",200:"#eeeeee",300:"#e0e0e0",400:"#bdbdbd",500:"#9e9e9e",600:"#757575",700:"#616161",800:"#424242",900:"#212121",A100:"#f5f5f5",A200:"#eeeeee",A400:"#bdbdbd",A700:"#616161"},jb=t4});var r4,ii,Wb=m(()=>{r4={50:"#f3e5f5",100:"#e1bee7",200:"#ce93d8",300:"#ba68c8",400:"#ab47bc",500:"#9c27b0",600:"#8e24aa",700:"#7b1fa2",800:"#6a1b9a",900:"#4a148c",A100:"#ea80fc",A200:"#e040fb",A400:"#d500f9",A700:"#aa00ff"},ii=r4});var n4,Or,Ep=m(()=>{n4={50:"#ffebee",100:"#ffcdd2",200:"#ef9a9a",300:"#e57373",400:"#ef5350",500:"#f44336",600:"#e53935",700:"#d32f2f",800:"#c62828",900:"#b71c1c",A100:"#ff8a80",A200:"#ff5252",A400:"#ff1744",A700:"#d50000"},Or=n4});var o4,Gn,bp=m(()=>{o4={50:"#fff3e0",100:"#ffe0b2",200:"#ffcc80",300:"#ffb74d",400:"#ffa726",500:"#ff9800",600:"#fb8c00",700:"#f57c00",800:"#ef6c00",900:"#e65100",A100:"#ffd180",A200:"#ffab40",A400:"#ff9100",A700:"#ff6d00"},Gn=o4});var i4,dn,wp=m(()=>{i4={50:"#e3f2fd",100:"#bbdefb",200:"#90caf9",300:"#64b5f6",400:"#42a5f5",500:"#2196f3",600:"#1e88e5",700:"#1976d2",800:"#1565c0",900:"#0d47a1",A100:"#82b1ff",A200:"#448aff",A400:"#2979ff",A700:"#2962ff"},dn=i4});var s4,si,Yb=m(()=>{s4={50:"#e1f5fe",100:"#b3e5fc",200:"#81d4fa",300:"#4fc3f7",400:"#29b6f6",500:"#03a9f4",600:"#039be5",700:"#0288d1",800:"#0277bd",900:"#01579b",A100:"#80d8ff",A200:"#40c4ff",A400:"#00b0ff",A700:"#0091ea"},si=s4});var a4,An,Ip=m(()=>{a4={50:"#e8f5e9",100:"#c8e6c9",200:"#a5d6a7",300:"#81c784",400:"#66bb6a",500:"#4caf50",600:"#43a047",700:"#388e3c",800:"#2e7d32",900:"#1b5e20",A100:"#b9f6ca",A200:"#69f0ae",A400:"#00e676",A700:"#00c853"},An=a4});function Jb(){return{text:{primary:"rgba(0, 0, 0, 0.87)",secondary:"rgba(0, 0, 0, 0.6)",disabled:"rgba(0, 0, 0, 0.38)"},divider:"rgba(0, 0, 0, 0.12)",background:{paper:Ns.white,default:Ns.white},action:{active:"rgba(0, 0, 0, 0.54)",hover:"rgba(0, 0, 0, 0.04)",hoverOpacity:.04,selected:"rgba(0, 0, 0, 0.08)",selectedOpacity:.08,disabled:"rgba(0, 0, 0, 0.26)",disabledBackground:"rgba(0, 0, 0, 0.12)",disabledOpacity:.38,focus:"rgba(0, 0, 0, 0.12)",focusOpacity:.12,activatedOpacity:.12}}}function Kb(){return{text:{primary:Ns.white,secondary:"rgba(255, 255, 255, 0.7)",disabled:"rgba(255, 255, 255, 0.5)",icon:"rgba(255, 255, 255, 0.5)"},divider:"rgba(255, 255, 255, 0.12)",background:{paper:"#121212",default:"#121212"},action:{active:Ns.white,hover:"rgba(255, 255, 255, 0.08)",hoverOpacity:.08,selected:"rgba(255, 255, 255, 0.16)",selectedOpacity:.16,disabled:"rgba(255, 255, 255, 0.3)",disabledBackground:"rgba(255, 255, 255, 0.12)",disabledOpacity:.38,focus:"rgba(255, 255, 255, 0.12)",focusOpacity:.12,activatedOpacity:.24}}}function qb(e,t,r,n){let o=n.light||n,i=n.dark||n*1.5;e[t]||(e.hasOwnProperty(r)?e[t]=e[r]:t==="light"?e.light=Ds(e.main,o):t==="dark"&&(e.dark=ks(e.main,i)))}function zb(e,t,r,n,o){let i=o.light||o,s=o.dark||o*1.5;t[r]||(t.hasOwnProperty(n)?t[r]=t[n]:r==="light"?t.light=`color-mix(in ${e}, ${t.main}, #fff ${(i*100).toFixed(0)}%)`:r==="dark"&&(t.dark=`color-mix(in ${e}, ${t.main}, #000 ${(s*100).toFixed(0)}%)`))}function c4(e="light"){return e==="dark"?{main:dn[200],light:dn[50],dark:dn[400]}:{main:dn[700],light:dn[400],dark:dn[800]}}function l4(e="light"){return e==="dark"?{main:ii[200],light:ii[50],dark:ii[400]}:{main:ii[500],light:ii[300],dark:ii[700]}}function u4(e="light"){return e==="dark"?{main:Or[500],light:Or[300],dark:Or[700]}:{main:Or[700],light:Or[400],dark:Or[800]}}function f4(e="light"){return e==="dark"?{main:si[400],light:si[300],dark:si[700]}:{main:si[700],light:si[500],dark:si[900]}}function d4(e="light"){return e==="dark"?{main:An[400],light:An[300],dark:An[700]}:{main:An[800],light:An[500],dark:An[900]}}function A4(e="light"){return e==="dark"?{main:Gn[400],light:Gn[300],dark:Gn[700]}:{main:"#ed6c02",light:Gn[500],dark:Gn[900]}}function m4(e){return`oklch(from ${e} var(--__l) 0 h / var(--__a))`}function ai(e){let{mode:t="light",contrastThreshold:r=3,tonalOffset:n=.2,colorSpace:o,...i}=e,s=e.primary||c4(t),a=e.secondary||l4(t),c=e.error||u4(t),l=e.info||f4(t),u=e.success||d4(t),d=e.warning||A4(t);function A(x){return o?m4(x):Eb(x,ef.text.primary)>=r?ef.text.primary:Sp.text.primary}let f=({color:x,name:w,mainShade:y=500,lightShade:v=300,darkShade:b=700})=>{if(x={...x},!x.main&&x[y]&&(x.main=x[y]),!x.hasOwnProperty("main"))throw new Error(Jt(11,w?` (${w})`:"",y));if(typeof x.main!="string")throw new Error(Jt(12,w?` (${w})`:"",JSON.stringify(x.main)));return o?(zb(o,x,"light",v,n),zb(o,x,"dark",b,n)):(qb(x,"light",v,n),qb(x,"dark",b,n)),x.contrastText||(x.contrastText=A(x.main)),x},g;return t==="light"?g=Jb():t==="dark"&&(g=Kb()),Je({common:{...Ns},mode:t,primary:f({color:s,name:"primary"}),secondary:f({color:a,name:"secondary",mainShade:"A400",lightShade:"A200",darkShade:"A700"}),error:f({color:c,name:"error"}),warning:f({color:d,name:"warning"}),info:f({color:l,name:"info"}),success:f({color:u,name:"success"}),grey:jb,contrastThreshold:r,getContrastText:A,augmentColor:f,tonalOffset:n,...g},i)}var Sp,ef,Ic=m(()=>{cs();Fn();Ec();Vb();$b();Wb();Ep();bp();wp();Yb();Ip();Sp=Jb();ef=Kb()});function tf(e){let t={};return Object.entries(e).forEach(n=>{let[o,i]=n;typeof i=="object"&&(t[o]=`${i.fontStyle?`${i.fontStyle} `:""}${i.fontVariant?`${i.fontVariant} `:""}${i.fontWeight?`${i.fontWeight} `:""}${i.fontStretch?`${i.fontStretch} `:""}${i.fontSize||""}${i.lineHeight?`/${i.lineHeight} `:""}${i.fontFamily||""}`)}),t}var Xb=m(()=>{});var Zb=m(()=>{_b();Xb();kb()});function vp(e,t){return{toolbar:{minHeight:56,[e.up("xs")]:{"@media (orientation: landscape)":{minHeight:48}},[e.up("sm")]:{minHeight:64}},...t}}var ew=m(()=>{});function p4(e){return Math.round(e*1e5)/1e5}function Bp(e,t){let{fontFamily:r=rw,fontSize:n=14,fontWeightLight:o=300,fontWeightRegular:i=400,fontWeightMedium:s=500,fontWeightBold:a=700,htmlFontSize:c=16,allVariants:l,pxToRem:u,...d}=typeof t=="function"?t(e):t,A=n/14,f=u||(x=>`${x/c*A}rem`),g=(x,w,y,v,b)=>({fontFamily:r,fontWeight:x,fontSize:f(w),lineHeight:y,...r===rw?{letterSpacing:`${p4(v/w)}em`}:{},...b,...l}),h={h1:g(o,96,1.167,-1.5),h2:g(o,60,1.2,-.5),h3:g(i,48,1.167,0),h4:g(i,34,1.235,.25),h5:g(i,24,1.334,0),h6:g(s,20,1.6,.15),subtitle1:g(i,16,1.75,.15),subtitle2:g(s,14,1.57,.1),body1:g(i,16,1.5,.15),body2:g(i,14,1.43,.15),button:g(s,14,1.75,.4,tw),caption:g(i,12,1.66,.4),overline:g(i,12,2.66,1,tw),inherit:{fontFamily:"inherit",fontWeight:"inherit",fontSize:"inherit",lineHeight:"inherit",letterSpacing:"inherit"}};return Je({htmlFontSize:c,pxToRem:f,fontFamily:r,fontSize:n,fontWeightLight:o,fontWeightRegular:i,fontWeightMedium:s,fontWeightBold:a,...h},d,{clone:!1})}var tw,rw,nw=m(()=>{Fn();tw={textTransform:"uppercase"},rw='"Roboto", "Helvetica", "Arial", sans-serif'});function De(...e){return[`${e[0]}px ${e[1]}px ${e[2]}px ${e[3]}px rgba(0,0,0,${.2})`,`${e[4]}px ${e[5]}px ${e[6]}px ${e[7]}px rgba(0,0,0,${.14})`,`${e[8]}px ${e[9]}px ${e[10]}px ${e[11]}px rgba(0,0,0,${.12})`].join(",")}var g4,ow,iw=m(()=>{g4=["none",De(0,2,1,-1,0,1,1,0,0,1,3,0),De(0,3,1,-2,0,2,2,0,0,1,5,0),De(0,3,3,-2,0,3,4,0,0,1,8,0),De(0,2,4,-1,0,4,5,0,0,1,10,0),De(0,3,5,-1,0,5,8,0,0,1,14,0),De(0,3,5,-1,0,6,10,0,0,1,18,0),De(0,4,5,-2,0,7,10,1,0,2,16,1),De(0,5,5,-3,0,8,10,1,0,3,14,2),De(0,5,6,-3,0,9,12,1,0,3,16,2),De(0,6,6,-3,0,10,14,1,0,4,18,3),De(0,6,7,-4,0,11,15,1,0,4,20,3),De(0,7,8,-4,0,12,17,2,0,5,22,4),De(0,7,8,-4,0,13,19,2,0,5,24,4),De(0,7,9,-4,0,14,21,2,0,5,26,4),De(0,8,9,-5,0,15,22,2,0,6,28,5),De(0,8,10,-5,0,16,24,2,0,6,30,5),De(0,8,11,-5,0,17,26,2,0,6,32,5),De(0,9,11,-5,0,18,28,2,0,7,34,6),De(0,9,12,-6,0,19,29,2,0,7,36,6),De(0,10,13,-6,0,20,31,3,0,8,38,7),De(0,10,13,-6,0,21,33,3,0,8,40,7),De(0,10,14,-6,0,22,35,3,0,8,42,7),De(0,11,14,-7,0,23,36,3,0,9,44,8),De(0,11,15,-7,0,24,38,3,0,9,46,8)],ow=g4});function sw(e){return`${Math.round(e)}ms`}function E4(e){if(!e)return 0;let t=e/36;return Math.min(Math.round((4+15*t**.25+t/5)*10),3e3)}function Tp(e){let t={...e};delete t.reducedMotion;let r={...x4,...t.easing},n={...C4,...t.duration},o=(s=h4,a=y4)=>{let{duration:c=n.standard,easing:l=r.easeInOut,delay:u=0,...d}=a;return(Array.isArray(s)?s:[s]).map(A=>`${A} ${typeof c=="string"?c:sw(c)} ${l} ${typeof u=="string"?u:sw(u)}`).join(",")},i=t.create??o;return{getAutoHeightDuration:E4,create:i,...t,easing:r,duration:n}}var h4,y4,x4,C4,aw=m(()=>{h4=["all"],y4={},x4={easeInOut:"cubic-bezier(0.4, 0, 0.2, 1)",easeOut:"cubic-bezier(0.0, 0, 0.2, 1)",easeIn:"cubic-bezier(0.4, 0, 1, 1)",sharp:"cubic-bezier(0.4, 0, 0.6, 1)"},C4={shortest:150,shorter:200,short:250,standard:300,complex:375,enteringScreen:225,leavingScreen:195}});function Mp(e=b4){return{reducedMotion:"never",...e}}var b4,cw=m(()=>{b4={}});var w4,lw,uw=m(()=>{w4={mobileStepper:1e3,fab:1050,speedDial:1050,appBar:1100,drawer:1200,modal:1300,snackbar:1400,tooltip:1500},lw=w4});function I4(e){return Pr(e)||typeof e>"u"||typeof e=="string"||typeof e=="boolean"||typeof e=="number"||Array.isArray(e)}function rf(e={}){let t={...e};function r(n){let o=Object.entries(n);for(let i=0;i<o.length;i++){let[s,a]=o[i];!I4(a)||s.startsWith("unstable_")||s.startsWith("internal_")?delete n[s]:Pr(a)&&(n[s]={...a},r(n[s]))}}return r(t),`import { unstable_createBreakpoints as createBreakpoints, createTransitions } from '@mui/material/styles';
 
 const theme = ${JSON.stringify(t,null,2)};
 
@@ -6,15 +6,15 @@ theme.breakpoints = createBreakpoints(theme.breakpoints || {});
 theme.motion = { reducedMotion: 'never', ...theme.motion };
 theme.transitions = createTransitions(theme.transitions || {});
 
-export default theme;`}var wp=m(()=>{Gn()});function KE(e){return typeof e=="number"?`${(e*100).toFixed(0)}%`:`calc((${e}) * 100%)`}function u4(e){Object.assign(e,{alpha(t,r){let n=this||e;return n.colorSpace?`oklch(from ${t} l c h / ${typeof r=="string"?`calc(${r})`:r})`:n.vars?`rgba(${t.replace(/var\(--([^,\s)]+)(?:,[^)]+)?\)+/g,"var(--$1Channel)")} / ${typeof r=="string"?`calc(${r})`:r})`:lp(t,l4(r))},lighten(t,r){let n=this||e;return n.colorSpace?`color-mix(in ${n.colorSpace}, ${t}, #fff ${KE(r)})`:Ns(t,r)},darken(t,r){let n=this||e;return n.colorSpace?`color-mix(in ${n.colorSpace}, ${t}, #000 ${KE(r)})`:Ds(t,r)}})}function f4(e={},...t){let{breakpoints:r,mixins:n={},spacing:o,palette:i={},motion:s={},transitions:a={},typography:c={},shape:l,colorSpace:u,...d}=e;if(e.vars&&e.generateThemeVars===void 0)throw new Error(Xt(22));let A=li({...i,colorSpace:u}),f=ii(e),g=Ke(f,{mixins:xp(f.breakpoints,n),palette:A,shadows:jE.slice(),typography:Cp(A,c),motion:Ep(s),transitions:bp(a),zIndex:{...zE}});return g=Ke(g,d),g=t.reduce((h,y)=>Ke(h,y),g),delete g.transitions.reducedMotion,g.unstable_sxConfig={...Un,...d?.unstable_sxConfig},g.unstable_sx=function(y){return Er({sx:y,theme:this})},g.toRuntimeSource=zu,u4(g),g}var l4,Ec,Ip=m(()=>{ls();Gn();tc();Ou();yc();GE();bc();VE();$E();YE();qE();JE();wp();l4=e=>{if(!Number.isNaN(+e))return+e;let t=e.match(/\d*\.?\d+/g);if(!t)return 0;let r=0;for(let n=0;n<t.length;n+=1)r+=+t[n];return r};Ec=f4});function Sp(e){let t;return e<1?t=5.11916*e**2:t=4.5*Math.log(e+1)+2,Math.round(t*10)/1e3}var XE=m(()=>{});function vp(e){return{inputPlaceholder:e==="dark"?.5:.42,inputUnderline:e==="dark"?.7:.42,switchTrackDisabled:e==="dark"?.2:.12,switchTrack:e==="dark"?.3:.38}}function Bp(e){return e==="dark"?d4:[]}function Tp(e){let{palette:t={mode:"light"},opacity:r,overlays:n,colorSpace:o,...i}=e,s=li({...t,colorSpace:o});return{palette:s,opacity:{...vp(s.mode),...r},overlays:n||Bp(s.mode),...i}}var d4,ZE=m(()=>{bc();XE();d4=[...Array(25)].map((e,t)=>{if(t===0)return"none";let r=Sp(t);return`linear-gradient(rgba(255 255 255 / ${r}), rgba(255 255 255 / ${r}))`})});function Mp(e){return e[0]==="motion"||!!e[0].match(/(cssVarPrefix|colorSchemeSelector|modularCssLayers|rootSelector|typography|mixins|breakpoints|direction|transitions)/)||!!e[0].match(/sxConfig$/)||e[0]==="palette"&&!!e[1]?.match(/(mode|contrastThreshold|tonalOffset)/)}var ew=m(()=>{});var A4,tw,rw=m(()=>{A4=e=>[...[...Array(25)].map((t,r)=>`--${e?`${e}-`:""}overlays-${r}`),`--${e?`${e}-`:""}palette-AppBar-darkBg`,`--${e?`${e}-`:""}palette-AppBar-darkColor`],tw=A4});var nw,ow=m(()=>{rw();nw=e=>(t,r)=>{let n=e.rootSelector||":root",o=e.colorSchemeSelector,i=o;if(o==="class"&&(i=".%s"),o==="data"&&(i="[data-%s]"),o?.startsWith("data-")&&!o.includes("%s")&&(i=`[${o}="%s"]`),e.defaultColorScheme===t){if(t==="dark"){let s={};return tw(e.cssVarPrefix).forEach(a=>{s[a]=r[a],delete r[a]}),i==="media"?{[n]:r,"@media (prefers-color-scheme: dark)":{[n]:s}}:i?{[i.replace("%s",t)]:s,[`${n}, ${i.replace("%s",t)}`]:r}:{[n]:{...r,...s}}}if(i&&i!=="media")return`${n}, ${i.replace("%s",String(t))}`}else if(t){if(i==="media")return{[`@media (prefers-color-scheme: ${String(t)})`]:{[n]:r}};if(i)return i.replace("%s",String(t))}return n}});function m4(e,t){t.forEach(r=>{e[r]||(e[r]={})})}function _(e,t,r){!e[t]&&r&&(e[t]=r)}function wc(e){return typeof e!="string"||!e.startsWith("hsl")?e:cp(e)}function jn(e,t){`${t}Channel`in e||(e[`${t}Channel`]=ks(wc(e[t]),`MUI: Can't create \`palette.${t}Channel\` because \`palette.${t}\` is not one of these formats: #nnn, #nnnnnn, rgb(), rgba(), hsl(), hsla(), color().
-To suppress this warning, you need to explicitly provide the \`palette.${t}Channel\` as a string (in rgb format, for example "12 12 12") or undefined if you want to remove the channel token.`))}function p4(e){return typeof e=="number"?`${e}px`:typeof e=="string"||typeof e=="function"||Array.isArray(e)?e:"8px"}function Rp(e,t,r,n,o){if(!r)return;r=r===!0?{}:r;let i=o==="dark"?"dark":"light";if(!n){t[o]=Tp({...r,palette:{mode:i,...r?.palette},colorSpace:e});return}let{palette:s,...a}=Ec({...n,palette:{mode:i,...r?.palette},colorSpace:e});return t[o]={...r,palette:s,opacity:{...vp(i),...r?.opacity},overlays:r?.overlays||Bp(i)},a}function Qp(e={},...t){let{colorSchemes:r={light:!0},defaultColorScheme:n,disableCssColorScheme:o=!1,cssVarPrefix:i="mui",nativeColor:s=!1,shouldSkipGeneratingVar:a=Mp,colorSchemeSelector:c=r.light&&r.dark?"media":void 0,rootSelector:l=":root",...u}=e,d=Object.keys(r)[0],A=n||(r.light&&d!=="light"?"light":d),f=g4(i),{[A]:g,light:h,dark:y,...E}=r,x={...E},S=g;if((A==="dark"&&!("dark"in r)||A==="light"&&!("light"in r))&&(S=!0),!S)throw new Error(Xt(21,A));let w;s&&(w="oklch");let I=Rp(w,x,S,u,A);h&&!x.light&&Rp(w,x,h,void 0,"light"),y&&!x.dark&&Rp(w,x,y,void 0,"dark");let v={defaultColorScheme:A,...I,cssVarPrefix:i,colorSchemeSelector:c,rootSelector:l,getCssVar:f,colorSchemes:x,font:{...qu(I.typography),...I.font},spacing:p4(u.spacing)};Object.keys(v.colorSchemes).forEach(F=>{let C=v.colorSchemes[F].palette,M=G=>{let j=G.split("-"),oe=j[1],te=j[2];return f(G,C[oe][te])};C.mode==="light"&&(_(C.common,"background","#fff"),_(C.common,"onBackground","#000")),C.mode==="dark"&&(_(C.common,"background","#000"),_(C.common,"onBackground","#fff"));function k(G,j,oe){if(w){let te;return G===xo&&(te=`transparent ${((1-oe)*100).toFixed(0)}%`),G===ce&&(te=`#000 ${(oe*100).toFixed(0)}%`),G===le&&(te=`#fff ${(oe*100).toFixed(0)}%`),`color-mix(in ${w}, ${j}, ${te})`}return G(j,oe)}if(m4(C,["Alert","AppBar","Avatar","Button","Chip","FilledInput","LinearProgress","Skeleton","Slider","SnackbarContent","SpeedDialAction","StepConnector","StepContent","Switch","TableCell","Tooltip"]),C.mode==="light"){_(C.Alert,"errorColor",k(ce,s?f("palette-error-light"):C.error.light,.6)),_(C.Alert,"infoColor",k(ce,s?f("palette-info-light"):C.info.light,.6)),_(C.Alert,"successColor",k(ce,s?f("palette-success-light"):C.success.light,.6)),_(C.Alert,"warningColor",k(ce,s?f("palette-warning-light"):C.warning.light,.6)),_(C.Alert,"errorFilledBg",M("palette-error-main")),_(C.Alert,"infoFilledBg",M("palette-info-main")),_(C.Alert,"successFilledBg",M("palette-success-main")),_(C.Alert,"warningFilledBg",M("palette-warning-main")),_(C.Alert,"errorFilledColor",Cn(()=>C.getContrastText(C.error.main))),_(C.Alert,"infoFilledColor",Cn(()=>C.getContrastText(C.info.main))),_(C.Alert,"successFilledColor",Cn(()=>C.getContrastText(C.success.main))),_(C.Alert,"warningFilledColor",Cn(()=>C.getContrastText(C.warning.main))),_(C.Alert,"errorStandardBg",k(le,s?f("palette-error-light"):C.error.light,.9)),_(C.Alert,"infoStandardBg",k(le,s?f("palette-info-light"):C.info.light,.9)),_(C.Alert,"successStandardBg",k(le,s?f("palette-success-light"):C.success.light,.9)),_(C.Alert,"warningStandardBg",k(le,s?f("palette-warning-light"):C.warning.light,.9)),_(C.Alert,"errorIconColor",M("palette-error-main")),_(C.Alert,"infoIconColor",M("palette-info-main")),_(C.Alert,"successIconColor",M("palette-success-main")),_(C.Alert,"warningIconColor",M("palette-warning-main")),_(C.AppBar,"defaultBg",M("palette-grey-100")),_(C.Avatar,"defaultBg",M("palette-grey-400")),_(C.Button,"inheritContainedBg",M("palette-grey-300")),_(C.Button,"inheritContainedHoverBg",M("palette-grey-A100")),_(C.Chip,"defaultBorder",M("palette-grey-400")),_(C.Chip,"defaultAvatarColor",M("palette-grey-700")),_(C.Chip,"defaultIconColor",M("palette-grey-700")),_(C.FilledInput,"bg","rgba(0, 0, 0, 0.06)"),_(C.FilledInput,"hoverBg","rgba(0, 0, 0, 0.09)"),_(C.FilledInput,"disabledBg","rgba(0, 0, 0, 0.12)"),_(C.LinearProgress,"primaryBg",k(le,s?f("palette-primary-main"):C.primary.main,.62)),_(C.LinearProgress,"secondaryBg",k(le,s?f("palette-secondary-main"):C.secondary.main,.62)),_(C.LinearProgress,"errorBg",k(le,s?f("palette-error-main"):C.error.main,.62)),_(C.LinearProgress,"infoBg",k(le,s?f("palette-info-main"):C.info.main,.62)),_(C.LinearProgress,"successBg",k(le,s?f("palette-success-main"):C.success.main,.62)),_(C.LinearProgress,"warningBg",k(le,s?f("palette-warning-light"):C.warning.main,.62)),_(C.Skeleton,"bg",w?k(xo,s?f("palette-text-primary"):C.text.primary,.11):`rgba(${M("palette-text-primaryChannel")} / 0.11)`),_(C.Slider,"primaryTrack",k(le,s?f("palette-primary-main"):C.primary.main,.62)),_(C.Slider,"secondaryTrack",k(le,s?f("palette-secondary-main"):C.secondary.main,.62)),_(C.Slider,"errorTrack",k(le,s?f("palette-error-main"):C.error.main,.62)),_(C.Slider,"infoTrack",k(le,s?f("palette-info-main"):C.info.main,.62)),_(C.Slider,"successTrack",k(le,s?f("palette-success-main"):C.success.main,.62)),_(C.Slider,"warningTrack",k(le,s?f("palette-warning-main"):C.warning.main,.62));let G=w?k(ce,s?f("palette-background-default"):C.background.default,.6825):hc(C.background.default,.8);_(C.SnackbarContent,"bg",G),_(C.SnackbarContent,"color",Cn(()=>w?Yu.text.primary:C.getContrastText(G))),_(C.SpeedDialAction,"fabHoverBg",hc(C.background.paper,.15)),_(C.StepConnector,"border",M("palette-grey-400")),_(C.StepContent,"border",M("palette-grey-400")),_(C.Switch,"defaultColor",M("palette-common-white")),_(C.Switch,"defaultDisabledColor",M("palette-grey-100")),_(C.Switch,"primaryDisabledColor",k(le,s?f("palette-primary-main"):C.primary.main,.62)),_(C.Switch,"secondaryDisabledColor",k(le,s?f("palette-secondary-main"):C.secondary.main,.62)),_(C.Switch,"errorDisabledColor",k(le,s?f("palette-error-main"):C.error.main,.62)),_(C.Switch,"infoDisabledColor",k(le,s?f("palette-info-main"):C.info.main,.62)),_(C.Switch,"successDisabledColor",k(le,s?f("palette-success-main"):C.success.main,.62)),_(C.Switch,"warningDisabledColor",k(le,s?f("palette-warning-main"):C.warning.main,.62)),_(C.TableCell,"border",k(le,xo(s?f("palette-divider"):C.divider,1),.88)),_(C.Tooltip,"bg",k(xo,s?f("palette-grey-700"):C.grey[700],.92))}if(C.mode==="dark"){_(C.Alert,"errorColor",k(le,s?f("palette-error-light"):C.error.light,.6)),_(C.Alert,"infoColor",k(le,s?f("palette-info-light"):C.info.light,.6)),_(C.Alert,"successColor",k(le,s?f("palette-success-light"):C.success.light,.6)),_(C.Alert,"warningColor",k(le,s?f("palette-warning-light"):C.warning.light,.6)),_(C.Alert,"errorFilledBg",M("palette-error-dark")),_(C.Alert,"infoFilledBg",M("palette-info-dark")),_(C.Alert,"successFilledBg",M("palette-success-dark")),_(C.Alert,"warningFilledBg",M("palette-warning-dark")),_(C.Alert,"errorFilledColor",Cn(()=>C.getContrastText(C.error.dark))),_(C.Alert,"infoFilledColor",Cn(()=>C.getContrastText(C.info.dark))),_(C.Alert,"successFilledColor",Cn(()=>C.getContrastText(C.success.dark))),_(C.Alert,"warningFilledColor",Cn(()=>C.getContrastText(C.warning.dark))),_(C.Alert,"errorStandardBg",k(ce,s?f("palette-error-light"):C.error.light,.9)),_(C.Alert,"infoStandardBg",k(ce,s?f("palette-info-light"):C.info.light,.9)),_(C.Alert,"successStandardBg",k(ce,s?f("palette-success-light"):C.success.light,.9)),_(C.Alert,"warningStandardBg",k(ce,s?f("palette-warning-light"):C.warning.light,.9)),_(C.Alert,"errorIconColor",M("palette-error-main")),_(C.Alert,"infoIconColor",M("palette-info-main")),_(C.Alert,"successIconColor",M("palette-success-main")),_(C.Alert,"warningIconColor",M("palette-warning-main")),_(C.AppBar,"defaultBg",M("palette-grey-900")),_(C.AppBar,"darkBg",M("palette-background-paper")),_(C.AppBar,"darkColor",M("palette-text-primary")),_(C.Avatar,"defaultBg",M("palette-grey-600")),_(C.Button,"inheritContainedBg",M("palette-grey-800")),_(C.Button,"inheritContainedHoverBg",M("palette-grey-700")),_(C.Chip,"defaultBorder",M("palette-grey-700")),_(C.Chip,"defaultAvatarColor",M("palette-grey-300")),_(C.Chip,"defaultIconColor",M("palette-grey-300")),_(C.FilledInput,"bg","rgba(255, 255, 255, 0.09)"),_(C.FilledInput,"hoverBg","rgba(255, 255, 255, 0.13)"),_(C.FilledInput,"disabledBg","rgba(255, 255, 255, 0.12)"),_(C.LinearProgress,"primaryBg",k(ce,s?f("palette-primary-main"):C.primary.main,.5)),_(C.LinearProgress,"secondaryBg",k(ce,s?f("palette-secondary-main"):C.secondary.main,.5)),_(C.LinearProgress,"errorBg",k(ce,s?f("palette-error-main"):C.error.main,.5)),_(C.LinearProgress,"infoBg",k(ce,s?f("palette-info-main"):C.info.main,.5)),_(C.LinearProgress,"successBg",k(ce,s?f("palette-success-main"):C.success.main,.5)),_(C.LinearProgress,"warningBg",k(ce,s?f("palette-warning-main"):C.warning.main,.5)),_(C.Skeleton,"bg",w?k(xo,s?f("palette-text-primary"):C.text.primary,.13):`rgba(${M("palette-text-primaryChannel")} / 0.13)`),_(C.Slider,"primaryTrack",k(ce,s?f("palette-primary-main"):C.primary.main,.5)),_(C.Slider,"secondaryTrack",k(ce,s?f("palette-secondary-main"):C.secondary.main,.5)),_(C.Slider,"errorTrack",k(ce,s?f("palette-error-main"):C.error.main,.5)),_(C.Slider,"infoTrack",k(ce,s?f("palette-info-main"):C.info.main,.5)),_(C.Slider,"successTrack",k(ce,s?f("palette-success-main"):C.success.main,.5)),_(C.Slider,"warningTrack",k(ce,s?f("palette-warning-light"):C.warning.main,.5));let G=w?k(le,s?f("palette-background-default"):C.background.default,.985):hc(C.background.default,.98);_(C.SnackbarContent,"bg",G),_(C.SnackbarContent,"color",Cn(()=>w?yp.text.primary:C.getContrastText(G))),_(C.SpeedDialAction,"fabHoverBg",hc(C.background.paper,.15)),_(C.StepConnector,"border",M("palette-grey-600")),_(C.StepContent,"border",M("palette-grey-600")),_(C.Switch,"defaultColor",M("palette-grey-300")),_(C.Switch,"defaultDisabledColor",M("palette-grey-600")),_(C.Switch,"primaryDisabledColor",k(ce,s?f("palette-primary-main"):C.primary.main,.55)),_(C.Switch,"secondaryDisabledColor",k(ce,s?f("palette-secondary-main"):C.secondary.main,.55)),_(C.Switch,"errorDisabledColor",k(ce,s?f("palette-error-main"):C.error.main,.55)),_(C.Switch,"infoDisabledColor",k(ce,s?f("palette-info-main"):C.info.main,.55)),_(C.Switch,"successDisabledColor",k(ce,s?f("palette-success-main"):C.success.main,.55)),_(C.Switch,"warningDisabledColor",k(ce,s?f("palette-warning-light"):C.warning.main,.55)),_(C.TableCell,"border",k(ce,xo(s?f("palette-divider"):C.divider,1),.68)),_(C.Tooltip,"bg",k(xo,s?f("palette-grey-700"):C.grey[700],.92))}s||(jn(C.background,"default"),jn(C.background,"paper"),jn(C.common,"background"),jn(C.common,"onBackground"),jn(C,"divider")),Object.keys(C).forEach(G=>{let j=C[G];G!=="tonalOffset"&&!s&&j&&typeof j=="object"&&(j.main&&_(C[G],"mainChannel",ks(wc(j.main))),j.light&&_(C[G],"lightChannel",ks(wc(j.light))),j.dark&&_(C[G],"darkChannel",ks(wc(j.dark))),j.contrastText&&_(C[G],"contrastTextChannel",ks(wc(j.contrastText))),G==="text"&&(jn(C[G],"primary"),jn(C[G],"secondary")),G==="action"&&(j.active&&jn(C[G],"active"),j.selected&&jn(C[G],"selected")))})}),v=t.reduce((F,C)=>Ke(F,C),v);let B={prefix:i,disableCssColorScheme:o,shouldSkipGeneratingVar:a,getSelector:nw(v),enableContrastVars:s},{vars:R,generateThemeVars:D,generateStyleSheets:L}=fp(v,B);return v.vars=R,Object.entries(v.colorSchemes[v.defaultColorScheme]).forEach(([F,C])=>{v[F]=C}),v.generateThemeVars=D,v.generateStyleSheets=L,v.generateSpacing=function(){return Ms(u.spacing,Ja(this))},v.getColorSchemeSelector=dp(c),v.spacing=v.generateSpacing(),v.shouldSkipGeneratingVar=a,v.unstable_sxConfig={...Un,...u?.unstable_sxConfig},v.unstable_sx=function(C){return Er({sx:C,theme:this})},v.internal_cache={},v.toRuntimeSource=zu,v}var Cn,g4,iw=m(()=>{ls();Gn();Ap();Xo();OE();tc();yc();Ip();ZE();ew();ow();wp();bc();Cn=e=>{try{return e()}catch{}},g4=(e="mui")=>Wu(e)});function sw(e,t,r){e.colorSchemes&&r&&(e.colorSchemes[t]={...r!==!0&&r,palette:li({...r===!0?{}:r.palette,mode:t})})}function _p(e={},...t){let{palette:r,cssVariables:n=!1,colorSchemes:o=r?void 0:{light:!0},defaultColorScheme:i=r?.mode,...s}=e,a=i||"light",c=o?.[a],l={...o,...r?{[a]:{...typeof c!="boolean"&&c,palette:r}}:void 0};if(n===!1){if(!("colorSchemes"in e))return Ec(e,...t);let u=r;"palette"in e||l[a]&&(l[a]!==!0?u=l[a].palette:a==="dark"&&(u={mode:"dark"}));let d=Ec({...e,palette:u},...t);return d.defaultColorScheme=a,d.colorSchemes=l,d.palette.mode==="light"&&(d.colorSchemes.light={...l.light!==!0&&l.light,palette:d.palette},sw(d,"dark",l.dark)),d.palette.mode==="dark"&&(d.colorSchemes.dark={...l.dark!==!0&&l.dark,palette:d.palette},sw(d,"light",l.light)),d}return!r&&!("light"in l)&&a==="light"&&(l.light=!0),Qp({...s,colorSchemes:l,defaultColorScheme:a,...typeof n!="boolean"&&n},...t)}var aw=m(()=>{bc();iw();Ip()});var h4,cw,lw=m(()=>{"use client";aw();h4=_p(),cw=h4});var uw,fw=m(()=>{uw="$$material"});function y4(e){return e!=="ownerState"&&e!=="theme"&&e!=="sx"&&e!=="as"}var dw,Aw=m(()=>{dw=y4});var x4,mw,pw=m(()=>{Aw();x4=e=>dw(e)&&e!=="classes",mw=x4});var C4,kp,gw=m(()=>{"use client";op();lw();fw();pw();C4=Hu({themeId:uw,defaultTheme:cw,rootShouldForwardProp:mw}),kp=C4});var b4,hw=m(()=>{b4=p(O(),1);gw()});var E4,yw,xw=m(()=>{Ap();E4=$u,yw=E4});function Dp(e){return up(e)}var hZ,w4,Cw=m(()=>{"use client";hZ=p(Q(),1);dE();w4=p(O(),1)});var bw=m(()=>{Cw()});function Ew(e){return Rs("MuiSvgIcon",e)}var SZ,Np=m(()=>{Qs();Zm();SZ=Sr("MuiSvgIcon",["root","colorPrimary","colorSecondary","colorAction","colorError","colorDisabled","fontSizeInherit","fontSizeSmall","fontSizeMedium","fontSizeLarge"])});function Iw(e,t){return e==="always"?t:e==="system"?{"@media (prefers-reduced-motion: reduce)":t}:null}var ww,Sw=m(()=>{ww={transition:"none"}});function B4(e,t){let r=t??ww;return Iw(e.motion?.reducedMotion,r)}function vw(e,t=S4,r=v4){let n=e.transitions?.create?.(t,r),o=B4(e);if(n===void 0)return o??I4;let i={transition:n};return o?{...i,...o}:i}var I4,S4,v4,Bw=m(()=>{Sw();I4={},S4=["all"],v4={}});var Ju,Ku,T4,M4,Tw,Lp,Mw=m(()=>{"use client";Ju=p(Q(),1);Yl();Xx();tC();hw();xw();bw();Np();Bw();Ku=p(O(),1),T4=e=>{let{color:t,fontSize:r,classes:n}=e,o={root:["root",t!=="inherit"&&`color${$a(t)}`,`fontSize${$a(r)}`]};return ql(o,Ew,n)},M4=kp("svg",{name:"MuiSvgIcon",slot:"Root",overridesResolver:(e,t)=>{let{ownerState:r}=e;return[t.root,r.color!=="inherit"&&t[`color${$a(r.color)}`],t[`fontSize${$a(r.fontSize)}`]]}})(yw(({theme:e})=>({userSelect:"none",width:"1em",height:"1em",display:"inline-block",flexShrink:0,...vw(e,"fill",{duration:(e.vars??e).transitions?.duration?.shorter}),variants:[{props:t=>!t.hasSvgAsChild,style:{fill:"currentColor"}},{props:{fontSize:"inherit"},style:{fontSize:"inherit"}},{props:{fontSize:"small"},style:{fontSize:e.typography?.pxToRem?.(20)||"1.25rem"}},{props:{fontSize:"medium"},style:{fontSize:e.typography?.pxToRem?.(24)||"1.5rem"}},{props:{fontSize:"large"},style:{fontSize:e.typography?.pxToRem?.(35)||"2.1875rem"}},...Object.entries((e.vars??e).palette).filter(([,t])=>t&&t.main).map(([t])=>({props:{color:t},style:{color:(e.vars??e).palette?.[t]?.main}})),{props:{color:"action"},style:{color:(e.vars??e).palette?.action?.active}},{props:{color:"disabled"},style:{color:(e.vars??e).palette?.action?.disabled}},{props:{color:"inherit"},style:{color:void 0}}]}))),Tw=Ju.forwardRef(function(t,r){let n=Dp({props:t,name:"MuiSvgIcon"}),{children:o,className:i,color:s="inherit",component:a="svg",fontSize:c="medium",htmlColor:l,inheritViewBox:u=!1,titleAccess:d,viewBox:A="0 0 24 24",...f}=n,g=Ju.isValidElement(o)&&o.type==="svg",h={...n,color:s,component:a,fontSize:c,instanceFontSize:t.fontSize,inheritViewBox:u,viewBox:A,hasSvgAsChild:g},y={};u||(y.viewBox=A);let E=T4(h);return(0,Ku.jsxs)(M4,{as:a,className:cs(E.root,i),focusable:"false",color:l,"aria-hidden":d?void 0:!0,role:d?"img":void 0,ref:r,...y,...f,...g&&o.props,ownerState:h,children:[g?o.props.children:o,d?(0,Ku.jsx)("title",{children:d}):null]})});Tw.muiName="SvgIcon";Lp=Tw});function Y(e,t){function r(n,o){return(0,Rw.jsx)(Lp,{"data-testid":void 0,ref:o,...n,children:e})}return r.muiName=Lp.muiName,Xu.memo(Xu.forwardRef(r))}var Xu,Rw,Qw=m(()=>{"use client";Xu=p(Q(),1);Mw();Rw=p(O(),1)});var _w=m(()=>{Qw();Np()});var Ie=m(()=>{"use client";_w()});var W=K((qZ,Nw)=>{Nw.exports=JBrowseExports["mobx-react"]});var Tt=K((zZ,Lw)=>{Lw.exports=JBrowseExports["tss-react/mui"]});var Pp=K((ZZ,Ow)=>{Ow.exports=JBrowseExports["@jbrowse/core/pluggableElementTypes"]});var Ps=K((tee,Hw)=>{Hw.exports=JBrowseExports.mobx});function ef(e){let{scrollX:t,msaAreaWidth:r,minimapHeight:n,colWidth:o,numColumns:i}=e,s=r/i/o,a=-t,c=a*s,l=(a+r)*s,u=Math.max(l-c,20),d=n-12,A=`${c+u},0 ${c},0 0,${d} ${r},${d}`;return{unit:s,s:c,w:u,polygonHeight:d,polygonPoints:A}}var Fp=m(()=>{});var fi,Vw,R4,jw,$w=m(()=>{fi=p(Q(),1),Vw=p(W(),1);Fp();R4=(0,Vw.observer)(({model:e})=>{let{msaAreaWidth:t}=e,{s:r,w:n,polygonPoints:o}=ef(e),i="rgb(66, 119, 127)",s=.3;return fi.default.createElement(fi.default.Fragment,null,fi.default.createElement("rect",{x:0,y:0,width:t,height:12,stroke:"#555",fill:"none"}),fi.default.createElement("rect",{x:Math.max(0,r),y:0,width:n,height:12,fill:i,fillOpacity:s,stroke:"#555"}),fi.default.createElement("g",{transform:`translate(0 ${12})`},fi.default.createElement("polygon",{fill:i,fillOpacity:s,points:o})))}),jw=R4});var Op,Gp,Ww,Yw,tf,rf,di,qw,nf,zw,Jw,Kw,Xw,Zw,eI,tI,rI,Ic=m(()=>{Op=new Set(["exon","CDS","five_prime_UTR","three_prime_UTR","UTR","intron"]),Gp=["#9fb6d4","#d4dcea"],Ww=!0,Yw=!1,tf=.2,rf=1,di=80,qw=!0,nf="maeditor",zw=!0,Jw=!0,Kw=!1,Xw=400,Zw=300,eI=!0,tI=!0,rI=!0});function Os({model:e,offsetY:t,blockSizeY:r}){let{leaves:n,rowHeight:o}=e,i=Math.max(0,Math.floor((t-o)/o)),s=Math.max(0,Math.ceil((t+r+o)/o));return n.slice(i,s)}var of=m(()=>{});function sf({model:e,offsetX:t,offsetY:r,ctx:n,highResScaleFactorOverride:o,blockSizeXOverride:i,blockSizeYOverride:s}){let{blockSize:a,rowHeight:c,highResScaleFactor:l,showDomains:u}=e;if(u){let d=o??l,A=i??a,f=s??a;n.resetTransform(),n.scale(d,d),n.translate(-t,c/2-r),_4({model:e,ctx:n,visibleLeaves:Os({model:e,offsetY:r,blockSizeY:f}),offsetX:t,blockWidth:A})}}function _4({model:e,ctx:t,visibleLeaves:r,offsetX:n,blockWidth:o}){let{subFeatureRows:i,colWidth:s,rowHeight:a,fillPalette:c,strokePalette:l,segmentLabels:u,showMsaLetters:d,domainBands:A}=e,f=i?4:a,g=!d&&!i&&f>=9,h=f+s,y=n-h,E=n+o+h;for(let x=0,S=r.length;x<S;x++){let w=r[x],I=w.x,v=A.get(w.data.name);if(v)for(let{annotation:B,startCol:R,endCol:D,stackIndex:L}of v){let{accession:F,strand:C}=B,M=R*s,k=s*(D-R);if(M+k>=y&&M<=E){let G=I-a+(i?L*f:0);if(t.fillStyle=c[F],t.strokeStyle=l[F],C===void 0){t.fillRect(M,G,k,f),t.strokeRect(M,G,k,f);let j=g?u.get(F):void 0;if(j!==void 0&&x===0){let oe=Math.min(f-2,11);t.font=`${oe}px sans-serif`,t.measureText(j).width+2<=k&&(t.fillStyle="#222",t.textAlign="center",t.textBaseline="middle",t.fillText(j,M+k/2,G+f/2))}}else k4({ctx:t,x:M,t:G,w:k,h:f,strand:C})}}}}function k4({ctx:e,x:t,t:r,w:n,h:o,strand:i}){let s=i>0?1:-1,a=i>0?t:t+n,c=i>0?t+n:t;e.beginPath(),e.moveTo(a,r),e.lineTo(c,r),e.lineTo(c+s*o,r+o/2),e.lineTo(c,r+o),e.lineTo(a,r+o),e.closePath(),e.fill(),e.stroke()}var Up=m(()=>{Ic();of()});function bn(e,t,r=!1){e.font=e.font.replace(/(?:bold )?[\d.]+px/,`${r?"bold ":""}${t}px`)}var Gs=m(()=>{});var D4,$n,ft,vr,uI,nI,Hp,N4,af,fI,dI,oI,iI,sI,Sc,L4,P4,F4,O4,$p,aI,G4,Vp,jp,cI,Wp,st,lI,cf,vc=m(()=>{D4={grad:.9,turn:360,rad:360/(2*Math.PI)},$n=function(e){return typeof e=="string"?e.length>0:typeof e=="number"},ft=function(e,t,r){return t===void 0&&(t=0),r===void 0&&(r=Math.pow(10,t)),Math.round(r*e)/r+0},vr=function(e,t,r){return t===void 0&&(t=0),r===void 0&&(r=1),e>r?r:e>t?e:t},uI=function(e){return(e=isFinite(e)?e%360:0)>0?e:e+360},nI=function(e){return{r:vr(e.r,0,255),g:vr(e.g,0,255),b:vr(e.b,0,255),a:vr(e.a)}},Hp=function(e){return{r:ft(e.r),g:ft(e.g),b:ft(e.b),a:ft(e.a,3)}},N4=/^#([0-9a-f]{3,8})$/i,af=function(e){var t=e.toString(16);return t.length<2?"0"+t:t},fI=function(e){var t=e.r,r=e.g,n=e.b,o=e.a,i=Math.max(t,r,n),s=i-Math.min(t,r,n),a=s?i===t?(r-n)/s:i===r?2+(n-t)/s:4+(t-r)/s:0;return{h:60*(a<0?a+6:a),s:i?s/i*100:0,v:i/255*100,a:o}},dI=function(e){var t=e.h,r=e.s,n=e.v,o=e.a;t=t/360*6,r/=100,n/=100;var i=Math.floor(t),s=n*(1-r),a=n*(1-(t-i)*r),c=n*(1-(1-t+i)*r),l=i%6;return{r:255*[n,a,s,s,c,n][l],g:255*[c,n,n,a,s,s][l],b:255*[s,s,c,n,n,a][l],a:o}},oI=function(e){return{h:uI(e.h),s:vr(e.s,0,100),l:vr(e.l,0,100),a:vr(e.a)}},iI=function(e){return{h:ft(e.h),s:ft(e.s),l:ft(e.l),a:ft(e.a,3)}},sI=function(e){return dI((r=(t=e).s,{h:t.h,s:(r*=((n=t.l)<50?n:100-n)/100)>0?2*r/(n+r)*100:0,v:n+r,a:t.a}));var t,r,n},Sc=function(e){return{h:(t=fI(e)).h,s:(o=(200-(r=t.s))*(n=t.v)/100)>0&&o<200?r*n/100/(o<=100?o:200-o)*100:0,l:o/2,a:t.a};var t,r,n,o},L4=/^hsla?\(\s*([+-]?\d*\.?\d+)(deg|rad|grad|turn)?\s*,\s*([+-]?\d*\.?\d+)%\s*,\s*([+-]?\d*\.?\d+)%\s*(?:,\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,P4=/^hsla?\(\s*([+-]?\d*\.?\d+)(deg|rad|grad|turn)?\s+([+-]?\d*\.?\d+)%\s+([+-]?\d*\.?\d+)%\s*(?:\/\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,F4=/^rgba?\(\s*([+-]?\d*\.?\d+)(%)?\s*,\s*([+-]?\d*\.?\d+)(%)?\s*,\s*([+-]?\d*\.?\d+)(%)?\s*(?:,\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,O4=/^rgba?\(\s*([+-]?\d*\.?\d+)(%)?\s+([+-]?\d*\.?\d+)(%)?\s+([+-]?\d*\.?\d+)(%)?\s*(?:\/\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,$p={string:[[function(e){var t=N4.exec(e);return t?(e=t[1]).length<=4?{r:parseInt(e[0]+e[0],16),g:parseInt(e[1]+e[1],16),b:parseInt(e[2]+e[2],16),a:e.length===4?ft(parseInt(e[3]+e[3],16)/255,2):1}:e.length===6||e.length===8?{r:parseInt(e.substr(0,2),16),g:parseInt(e.substr(2,2),16),b:parseInt(e.substr(4,2),16),a:e.length===8?ft(parseInt(e.substr(6,2),16)/255,2):1}:null:null},"hex"],[function(e){var t=F4.exec(e)||O4.exec(e);return t?t[2]!==t[4]||t[4]!==t[6]?null:nI({r:Number(t[1])/(t[2]?100/255:1),g:Number(t[3])/(t[4]?100/255:1),b:Number(t[5])/(t[6]?100/255:1),a:t[7]===void 0?1:Number(t[7])/(t[8]?100:1)}):null},"rgb"],[function(e){var t=L4.exec(e)||P4.exec(e);if(!t)return null;var r,n,o=oI({h:(r=t[1],n=t[2],n===void 0&&(n="deg"),Number(r)*(D4[n]||1)),s:Number(t[3]),l:Number(t[4]),a:t[5]===void 0?1:Number(t[5])/(t[6]?100:1)});return sI(o)},"hsl"]],object:[[function(e){var t=e.r,r=e.g,n=e.b,o=e.a,i=o===void 0?1:o;return $n(t)&&$n(r)&&$n(n)?nI({r:Number(t),g:Number(r),b:Number(n),a:Number(i)}):null},"rgb"],[function(e){var t=e.h,r=e.s,n=e.l,o=e.a,i=o===void 0?1:o;if(!$n(t)||!$n(r)||!$n(n))return null;var s=oI({h:Number(t),s:Number(r),l:Number(n),a:Number(i)});return sI(s)},"hsl"],[function(e){var t=e.h,r=e.s,n=e.v,o=e.a,i=o===void 0?1:o;if(!$n(t)||!$n(r)||!$n(n))return null;var s=(function(a){return{h:uI(a.h),s:vr(a.s,0,100),v:vr(a.v,0,100),a:vr(a.a)}})({h:Number(t),s:Number(r),v:Number(n),a:Number(i)});return dI(s)},"hsv"]]},aI=function(e,t){for(var r=0;r<t.length;r++){var n=t[r][0](e);if(n)return[n,t[r][1]]}return[null,void 0]},G4=function(e){return typeof e=="string"?aI(e.trim(),$p.string):typeof e=="object"&&e!==null?aI(e,$p.object):[null,void 0]},Vp=function(e,t){var r=Sc(e);return{h:r.h,s:vr(r.s+100*t,0,100),l:r.l,a:r.a}},jp=function(e){return(299*e.r+587*e.g+114*e.b)/1e3/255},cI=function(e,t){var r=Sc(e);return{h:r.h,s:r.s,l:vr(r.l+100*t,0,100),a:r.a}},Wp=(function(){function e(t){this.parsed=G4(t)[0],this.rgba=this.parsed||{r:0,g:0,b:0,a:1}}return e.prototype.isValid=function(){return this.parsed!==null},e.prototype.brightness=function(){return ft(jp(this.rgba),2)},e.prototype.isDark=function(){return jp(this.rgba)<.5},e.prototype.isLight=function(){return jp(this.rgba)>=.5},e.prototype.toHex=function(){return t=Hp(this.rgba),r=t.r,n=t.g,o=t.b,s=(i=t.a)<1?af(ft(255*i)):"","#"+af(r)+af(n)+af(o)+s;var t,r,n,o,i,s},e.prototype.toRgb=function(){return Hp(this.rgba)},e.prototype.toRgbString=function(){return t=Hp(this.rgba),r=t.r,n=t.g,o=t.b,(i=t.a)<1?"rgba("+r+", "+n+", "+o+", "+i+")":"rgb("+r+", "+n+", "+o+")";var t,r,n,o,i},e.prototype.toHsl=function(){return iI(Sc(this.rgba))},e.prototype.toHslString=function(){return t=iI(Sc(this.rgba)),r=t.h,n=t.s,o=t.l,(i=t.a)<1?"hsla("+r+", "+n+"%, "+o+"%, "+i+")":"hsl("+r+", "+n+"%, "+o+"%)";var t,r,n,o,i},e.prototype.toHsv=function(){return t=fI(this.rgba),{h:ft(t.h),s:ft(t.s),v:ft(t.v),a:ft(t.a,3)};var t},e.prototype.invert=function(){return st({r:255-(t=this.rgba).r,g:255-t.g,b:255-t.b,a:t.a});var t},e.prototype.saturate=function(t){return t===void 0&&(t=.1),st(Vp(this.rgba,t))},e.prototype.desaturate=function(t){return t===void 0&&(t=.1),st(Vp(this.rgba,-t))},e.prototype.grayscale=function(){return st(Vp(this.rgba,-1))},e.prototype.lighten=function(t){return t===void 0&&(t=.1),st(cI(this.rgba,t))},e.prototype.darken=function(t){return t===void 0&&(t=.1),st(cI(this.rgba,-t))},e.prototype.rotate=function(t){return t===void 0&&(t=15),this.hue(this.hue()+t)},e.prototype.alpha=function(t){return typeof t=="number"?st({r:(r=this.rgba).r,g:r.g,b:r.b,a:t}):ft(this.rgba.a,3);var r},e.prototype.hue=function(t){var r=Sc(this.rgba);return typeof t=="number"?st({h:t,s:r.s,l:r.l,a:r.a}):ft(r.h)},e.prototype.isEqual=function(t){return this.toHex()===st(t).toHex()},e})(),st=function(e){return e instanceof Wp?e:new Wp(e)},lI=[],cf=function(e){e.forEach(function(t){lI.indexOf(t)<0&&(t(Wp,$p),lI.push(t))})}});function AI(e){e.prototype.luminance=function(){return t=qp(this.rgba),(r=2)===void 0&&(r=0),n===void 0&&(n=Math.pow(10,r)),Math.round(n*t)/n+0;var t,r,n},e.prototype.contrast=function(t){t===void 0&&(t="#FFF");var r,n,o,i,s,a,c,l=t instanceof e?t:new e(t);return i=this.rgba,s=l.toRgb(),a=qp(i),c=qp(s),r=a>c?(a+.05)/(c+.05):(c+.05)/(a+.05),(n=2)===void 0&&(n=0),o===void 0&&(o=Math.pow(10,n)),Math.floor(o*r)/o+0},e.prototype.isReadable=function(t,r){return t===void 0&&(t="#FFF"),r===void 0&&(r={}),this.contrast(t)>=(a=(s=(n=r).size)===void 0?"normal":s,(i=(o=n.level)===void 0?"AA":o)==="AAA"&&a==="normal"?7:i==="AA"&&a==="large"?3:4.5);var n,o,i,s,a}}var Yp,qp,mI=m(()=>{Yp=function(e){var t=e/255;return t<.04045?t/12.92:Math.pow((t+.055)/1.055,2.4)},qp=function(e){return .2126*Yp(e.r)+.7152*Yp(e.g)+.0722*Yp(e.b)}});function lf(e,t){var r={white:"#ffffff",bisque:"#ffe4c4",blue:"#0000ff",cadetblue:"#5f9ea0",chartreuse:"#7fff00",chocolate:"#d2691e",coral:"#ff7f50",antiquewhite:"#faebd7",aqua:"#00ffff",azure:"#f0ffff",whitesmoke:"#f5f5f5",papayawhip:"#ffefd5",plum:"#dda0dd",blanchedalmond:"#ffebcd",black:"#000000",gold:"#ffd700",goldenrod:"#daa520",gainsboro:"#dcdcdc",cornsilk:"#fff8dc",cornflowerblue:"#6495ed",burlywood:"#deb887",aquamarine:"#7fffd4",beige:"#f5f5dc",crimson:"#dc143c",cyan:"#00ffff",darkblue:"#00008b",darkcyan:"#008b8b",darkgoldenrod:"#b8860b",darkkhaki:"#bdb76b",darkgray:"#a9a9a9",darkgreen:"#006400",darkgrey:"#a9a9a9",peachpuff:"#ffdab9",darkmagenta:"#8b008b",darkred:"#8b0000",darkorchid:"#9932cc",darkorange:"#ff8c00",darkslateblue:"#483d8b",gray:"#808080",darkslategray:"#2f4f4f",darkslategrey:"#2f4f4f",deeppink:"#ff1493",deepskyblue:"#00bfff",wheat:"#f5deb3",firebrick:"#b22222",floralwhite:"#fffaf0",ghostwhite:"#f8f8ff",darkviolet:"#9400d3",magenta:"#ff00ff",green:"#008000",dodgerblue:"#1e90ff",grey:"#808080",honeydew:"#f0fff0",hotpink:"#ff69b4",blueviolet:"#8a2be2",forestgreen:"#228b22",lawngreen:"#7cfc00",indianred:"#cd5c5c",indigo:"#4b0082",fuchsia:"#ff00ff",brown:"#a52a2a",maroon:"#800000",mediumblue:"#0000cd",lightcoral:"#f08080",darkturquoise:"#00ced1",lightcyan:"#e0ffff",ivory:"#fffff0",lightyellow:"#ffffe0",lightsalmon:"#ffa07a",lightseagreen:"#20b2aa",linen:"#faf0e6",mediumaquamarine:"#66cdaa",lemonchiffon:"#fffacd",lime:"#00ff00",khaki:"#f0e68c",mediumseagreen:"#3cb371",limegreen:"#32cd32",mediumspringgreen:"#00fa9a",lightskyblue:"#87cefa",lightblue:"#add8e6",midnightblue:"#191970",lightpink:"#ffb6c1",mistyrose:"#ffe4e1",moccasin:"#ffe4b5",mintcream:"#f5fffa",lightslategray:"#778899",lightslategrey:"#778899",navajowhite:"#ffdead",navy:"#000080",mediumvioletred:"#c71585",powderblue:"#b0e0e6",palegoldenrod:"#eee8aa",oldlace:"#fdf5e6",paleturquoise:"#afeeee",mediumturquoise:"#48d1cc",mediumorchid:"#ba55d3",rebeccapurple:"#663399",lightsteelblue:"#b0c4de",mediumslateblue:"#7b68ee",thistle:"#d8bfd8",tan:"#d2b48c",orchid:"#da70d6",mediumpurple:"#9370db",purple:"#800080",pink:"#ffc0cb",skyblue:"#87ceeb",springgreen:"#00ff7f",palegreen:"#98fb98",red:"#ff0000",yellow:"#ffff00",slateblue:"#6a5acd",lavenderblush:"#fff0f5",peru:"#cd853f",palevioletred:"#db7093",violet:"#ee82ee",teal:"#008080",slategray:"#708090",slategrey:"#708090",aliceblue:"#f0f8ff",darkseagreen:"#8fbc8f",darkolivegreen:"#556b2f",greenyellow:"#adff2f",seagreen:"#2e8b57",seashell:"#fff5ee",tomato:"#ff6347",silver:"#c0c0c0",sienna:"#a0522d",lavender:"#e6e6fa",lightgreen:"#90ee90",orange:"#ffa500",orangered:"#ff4500",steelblue:"#4682b4",royalblue:"#4169e1",turquoise:"#40e0d0",yellowgreen:"#9acd32",salmon:"#fa8072",saddlebrown:"#8b4513",sandybrown:"#f4a460",rosybrown:"#bc8f8f",darksalmon:"#e9967a",lightgoldenrodyellow:"#fafad2",snow:"#fffafa",lightgrey:"#d3d3d3",lightgray:"#d3d3d3",dimgray:"#696969",dimgrey:"#696969",olivedrab:"#6b8e23",olive:"#808000"},n={};for(var o in r)n[r[o]]=o;var i={};e.prototype.toName=function(s){if(!(this.rgba.a||this.rgba.r||this.rgba.g||this.rgba.b))return"transparent";var a,c,l=n[this.toHex()];if(l)return l;if(s?.closest){var u=this.toRgb(),d=1/0,A="black";if(!i.length)for(var f in r)i[f]=new e(r[f]).toRgb();for(var g in r){var h=(a=u,c=i[g],Math.pow(a.r-c.r,2)+Math.pow(a.g-c.g,2)+Math.pow(a.b-c.b,2));h<d&&(d=h,A=g)}return A}},t.string.push([function(s){var a=s.toLowerCase(),c=a==="transparent"?"#0000":r[a];return c?new e(c).toRgb():null},"name"])}var zp=m(()=>{});function gI(e,t){let r=`${e}|${t}`,n=pI.get(r);if(n!==void 0)return n;let o=st(e);if(!o.isReadable(t)){let s=st(t).luminance()<.5;for(let a=0;a<40&&!o.isReadable(t);a++)o=s?o.lighten(.05):o.darken(.05)}let i=o.toHex();return pI.set(r,i),i}function Us(e,t){return Object.fromEntries(Object.entries(e).map(t))}function Bc(e,t){return Us(e,([r,n])=>[r,t.palette.getContrastText(st(n).toHex())])}function Jp(e,t){if(e.length===0)return t;let r=[],n=0;for(let o of e)o>n&&r.push(t.slice(n,o)),n=o+1;return n<t.length&&r.push(t.slice(n)),r.join("")}function hI(e,t){let r=[],n=e.length,o=0,i=0,s=-1,a=[];for(let c=0;c<t.length;c++)i<n&&e[i]===c?(t.charCodeAt(c)-45>>>0<=1||(s===o?a.push(t[c]):(a.length>0&&r.push({pos:s,letters:a.join("")}),s=o,a=[t[c]])),i++):o++;return a.length>0&&r.push({pos:s,letters:a.join("")}),r}function Kp(e){return e.end-e.start}function uf(e){return e==="-"||e==="."}var pI,Co=m(()=>{vc();mI();zp();cf([lf,AI]);pI=new Map});function Tc({offsetX:e,blockWidth:t,colWidth:r}){return{xStart:Math.max(0,Math.floor(e/r)),xEnd:Math.max(0,Math.ceil((e+t)/r))}}var Xp=m(()=>{});function ff({model:e,offsetX:t,offsetY:r,contrastScheme:n,ctx:o,theme:i,highResScaleFactorOverride:s,blockSizeXOverride:a,blockSizeYOverride:c}){let{colWidth:l,blockSize:u,rowHeight:d,fontSize:A,highResScaleFactor:f,actuallyShowDomains:g,bgColor:h}=e,y=s??f,E=a??u,x=c??u;o.resetTransform(),o.scale(y,y),o.translate(-t,d/2-r),o.textAlign="center",o.textBaseline="alphabetic",bn(o,A,!h);let{xStart:S,xEnd:w}=Tc({offsetX:t,blockWidth:E,colWidth:l}),I=Os({model:e,offsetY:r,blockSizeY:x}),{relativeTo:v,columns:B}=e,R=v?B.get(v)?.slice(S,w):null;V4({model:e,ctx:o,theme:i,contrastScheme:n,xStart:S,xEnd:w,visibleLeaves:I,referenceSeq:R,drawTiles:!g}),j4({model:e,ctx:o,xStart:S,xEnd:w,visibleLeaves:I}),o.resetTransform()}function U4(e){let{colorSchemeName:t,colorScheme:r,colClustalX:n,colConsensus:o}=e;return t==="clustalx_protein_dynamic"?(i,s)=>n[i][s]:t==="percent_identity_dynamic"?(i,s)=>{let a=o[i];return s===a.letter?a.color:void 0}:(i,s)=>r[s]}function H4(e,t){return new Map(Object.entries(e.fillPalette).map(([r,n])=>[r,t.palette.getContrastText(n)]))}function V4({model:e,ctx:t,theme:r,contrastScheme:n,visibleLeaves:o,xStart:i,xEnd:s,referenceSeq:a,drawTiles:c}){let{bgColor:l,columns:u,colWidth:d,rowHeight:A,relativeTo:f,showMsaLetters:g,subFeatureRows:h,domainBandsByStart:y}=e,E=c&&l;if(E||g){let x=U4(e),S=i*d,w=d/2,I=A/4,v=!c&&!h,B=v?H4(e,r):void 0;for(let R=0,D=o.length;R<D;R++){let L=o[R],{name:F}=L.data,C=L.x,M=u.get(F)?.slice(i,s);if(M){let k=C-A,G=C-I,j=v?y.get(F):void 0,oe=0;for(let te=0,Gr=M.length;te<Gr;te++){let it=i+te,de=M[te],Ur=te*d+S,xr=a&&F!==f&&de===a[te],un=x(it,de);if(E&&(t.fillStyle=xr?r.palette.action.hover:un||r.palette.background.default,t.fillRect(Ur,k,d,A)),g){for(;j&&oe<j.length&&j[oe].endCol<=it;)oe++;let Pn=j?.[oe];t.fillStyle=Pn&&Pn.startCol<=it?B.get(Pn.annotation.accession):E?n[de]??"black":!c||!un?r.palette.text.primary:gI(un,r.palette.background.default),t.fillText(xr?".":de,Ur+w,G)}}}}}}function j4({model:e,ctx:t,visibleLeaves:r,xStart:n,xEnd:o}){let{bgColor:i,hideGapsEffective:s}=e;s&&(t.lineWidth=1,t.strokeStyle="#f0f",yI({visibleLeaves:r,xStart:n,ctx:t,model:e,xEnd:o,offset:0}),t.strokeStyle=i?"#fff":"#000",yI({visibleLeaves:r,xStart:n,ctx:t,model:e,xEnd:o,offset:-1}))}function yI({model:e,ctx:t,visibleLeaves:r,xStart:n,xEnd:o,offset:i}){let{colWidth:a,rowHeight:c,insertionPositions:l}=e;for(let u of r){let{name:d}=u.data,A=l.get(d);if(A){let f=u.x;for(let{pos:g}of A)if(g>=n&&g<o){let h=g*a,y=f-c,E=f;t.beginPath(),t.moveTo(h+i,y+i);let x=y,S=!0;for(;x<E;){let w=Math.min(x+2,E),I=S?h+1:h-1;t.lineTo(I+i,w+i),x=w,S=!S}t.stroke()}}}}var Zp=m(()=>{Gs();Co();of();Xp()});function eg({ctx:e,values:t,color:r,colWidth:n,trackHeight:o,offsetX:i,blockSize:s}){let{xStart:a,xEnd:c}=Tc({offsetX:i,blockWidth:s,colWidth:n});e.fillStyle=r;for(let l=a;l<c&&l<t.length;l++){let d=t[l]*o,A=l*n;e.fillRect(A,o-d,n,d)}}function tg(e,t){return t==="property-conservation"?e.propertyConservation:e.conservation}function rg({ctx:e,data:t,colorScheme:r,contrastScheme:n,bgColor:o,textColor:i,colWidth:s,rowHeight:a,offsetX:c,blockSize:l}){let{xStart:u,xEnd:d}=Tc({offsetX:c,blockWidth:l,colWidth:s}),A=t?.slice(u,d),f=a>=10&&s>=a/2;for(let g=0;A&&g<A.length;g++){let h=A[g],y=h.toUpperCase(),E=r[y],x=(u+g)*s,S=o&&!!E;S&&(e.fillStyle=E,e.fillRect(x,0,s,a)),f&&(e.fillStyle=S?n[y]??"black":i,e.fillText(h,x+s/2,a/2+1))}}function $4({model:e,ctx:t,track:r,offsetX:n,offsetY:o,trackHeight:i,blockSizeXOverride:s,highResScaleFactorOverride:a}){let{blockSize:c,colWidth:l,highResScaleFactor:u}=e,d=s??c,A=a??u;t.resetTransform(),t.scale(A,A),t.translate(-n,o),eg({ctx:t,values:tg(e,r.model.id),color:r.model.barColor??"gray",colWidth:l,trackHeight:i,offsetX:n,blockSize:d}),t.resetTransform()}function W4({model:e,ctx:t,track:r,offsetX:n,offsetY:o,contrastScheme:i,theme:s,blockSizeXOverride:a,highResScaleFactorOverride:c}){let{blockSize:l,bgColor:u,colorScheme:d,colWidth:A,fontSize:f,rowHeight:g,highResScaleFactor:h}=e,{customColorScheme:y,data:E}=r.model,x=y??d,S=a??l,w=c??h;t.resetTransform(),t.scale(w,w),t.translate(-n,o),t.textAlign="center",bn(t,f),rg({ctx:t,data:E,colorScheme:x,contrastScheme:i,bgColor:u,textColor:s.palette.text.primary,colWidth:A,rowHeight:g,offsetX:n,blockSize:S}),t.resetTransform()}function xI({model:e,ctx:t,offsetX:r,contrastScheme:n,theme:o,blockSizeXOverride:i,highResScaleFactorOverride:s}){let{turnedOnTracks:a}=e,c=0;for(let l of a){let u=l.model.height;l.model.barColor!==void 0?$4({model:e,ctx:t,track:l,offsetX:r,offsetY:c,trackHeight:u,blockSizeXOverride:i,highResScaleFactorOverride:s}):W4({model:e,ctx:t,track:l,offsetX:r,offsetY:c,contrastScheme:n,theme:o,blockSizeXOverride:i,highResScaleFactorOverride:s}),c+=u}}var df=m(()=>{Gs();Xp()});function Ai(e){let t=[],r=[e];for(;r.length>0;){let n=r.pop();if(t.push(n),n.children)for(let o=n.children.length-1;o>=0;o--)r.push(n.children[o])}return t}function Y4(e){let t=Ai(e);for(let r=t.length-1;r>=0;r--){let n=t[r],o=0;if(n.children)for(let i of n.children)i.height+1>o&&(o=i.height+1);n.height=o}}function CI(e,t){let r={data:e,children:null,parent:null,depth:0,height:0},n=[r];for(;n.length>0;){let o=n.pop(),i=t(o.data);if(i?.length){o.children=i.map(s=>({data:s,children:null,parent:o,depth:o.depth+1,height:0}));for(let s of o.children)n.push(s)}}return Y4(r),r}function bI(e,t){let r=Ai(e);for(let n=r.length-1;n>=0;n--){let o=r[n],i=t(o.data);if(o.children)for(let s of o.children)i+=s.value;o.value=i}return e}function EI(e,t){let r=[e];for(;r.length>0;){let n=r.pop();if(n.children){n.children.sort(t);for(let o of n.children)r.push(o)}}return e}function Af(e,t){let r=[e],n;for(;r.length>0&&n===void 0;){let o=r.pop();if(t(o))n=o;else if(o.children)for(let i=o.children.length-1;i>=0;i--)r.push(o.children[i])}return n}function Mc(e){let t=[],r=[e];for(;r.length>0;){let n=r.pop();if(n.children)for(let o=n.children.length-1;o>=0;o--)r.push(n.children[o]);else t.push(n)}return t}function wI(e){let t=[];return ng(e,(r,n)=>{t.push({source:r,target:n})}),t}function ng(e,t){let r=[e];for(;r.length>0;){let n=r.pop();if(n.children)for(let o=n.children.length-1;o>=0;o--){let i=n.children[o];t(n,i),r.push(i)}}}function Rc(e,t){for(let r of Ai(e))t(r)}function II(e,t,r){let n=Mc(e),o=n.length,i=t/o;for(let l=0;l<o;l++)n[l].x=(l+.5)*i;let s=Ai(e);for(let l=s.length-1;l>=0;l--){let u=s[l];if(u.children){let d=0;for(let A of u.children)d+=A.x;u.x=d/u.children.length}}let a=e.height,c=[{node:e,depth:0}];for(;c.length>0;){let{node:l,depth:u}=c.pop();if(l.y=a===0?r:u/a*r,l.children)for(let d of l.children)c.push({node:d,depth:u+1})}}function SI(e){e.children&&(Qc(e),e._children=e.children,e.children=null)}function vI(e){let t=e._children??e.children,r=1/0,n=0;if(t){let o=t.map(i=>({node:i,acc:Math.max(i.data.length??0,0)}));for(;o.length>0;){let{node:i,acc:s}=o.pop(),a=i.children??i._children;if(a?.length)for(let c of a)o.push({node:c,acc:s+Math.max(c.data.length??0,0)});else r=Math.min(r,s),n=Math.max(n,s)}}return{min:r===1/0?0:r,max:n}}function Qc(e){if(e.depthToLeaf===void 0){let t=Ai(e);for(let r=t.length-1;r>=0;r--){let n=t[r];if(n.depthToLeaf===void 0){let o=0;if(n.children)for(let i of n.children)o=Math.max(o,1+i.depthToLeaf);n.depthToLeaf=o}}}return e.depthToLeaf}function BI(e){let t=0;for(let r of Ai(e))t=Math.max(t,r.len||0);return t}function TI(e){let t=Ai(e),r=new Map;for(let n=t.length-1;n>=0;n--){let o=t[n],i=0;if(o.children)for(let s of o.children)i=Math.max(i,r.get(s));r.set(o,(o.data.length||0)+i)}return r.get(e)}function MI(e,t,r){let n=[{node:e,y0:t}];for(;n.length>0;){let{node:o,y0:i}=n.pop(),s=i+Math.max(o.data.length||0,0);if(o.len=s*r,o.children)for(let a of o.children)n.push({node:a,y0:s})}}var og=m(()=>{});function sg(e,t,r){return e>t-RI&&e<t+r+RI}function _c(e,t,r,n){if(t)return e.len;if(n===0)return 0;let o=Qc(e);return(n-o)/n*r}function q4({offsetY:e,ctx:t,model:r,theme:n,maxBranchLen:o,maxDepthToLeaf:i,blockSizeYOverride:s}){let{hierarchy:a,showBranchLenEffective:c,blockSize:l}=r,u=s??l;t.strokeStyle=n.palette.text.primary,ng(a,(d,A)=>{let f=d.x,g=A.x,h=_c(A,c,o,i),y=_c(d,c,o,i);if(h===void 0||y===void 0)return;let E=Math.min(f,g),x=Math.max(f,g);e+u>=E&&x>=e&&(t.beginPath(),t.moveTo(y,f),t.lineTo(y,g),t.lineTo(h,g),t.stroke())})}function z4({ctx:e,clickMap:t,offsetY:r,model:n,theme:o,maxBranchLen:i,maxDepthToLeaf:s,blockSizeYOverride:a}){let{hierarchy:c,showBranchLenEffective:l,collapsed:u,blockSize:d,rowHeight:A,fontSize:f,marginLeft:g}=n,h=a??d,y=Math.max(2,A*.42);Rc(c,E=>{let{id:x,name:S}=E.data;if(u.includes(x)){let w=_c(E,l,i,s),I=E.x,v=sg(I,r,h),B=l?E.collapsedTipXFar??i:i;if(w!==void 0&&v&&B>w){e.beginPath(),e.moveTo(w,I),e.lineTo(B,I-y),e.lineTo(B,I+y),e.closePath(),e.fillStyle=o.palette.action.disabled,e.fill(),e.strokeStyle=o.palette.text.primary,e.stroke();let R=E.value;R!==void 0&&A>=8&&(e.fillStyle=o.palette.text.primary,e.textAlign="left",e.fillText(`${R}`,B+3,I+f/4));let D=S===x?"Collapsed clade":S;t?.insert({minX:w+g,maxX:B+g,minY:I-y,maxY:I+y,branch:!0,id:x,name:R===void 0?D:`${D} (${R} tips)`})}}})}function J4({ctx:e,clickMap:t,offsetY:r,model:n,maxBranchLen:o,maxDepthToLeaf:i,blockSizeYOverride:s}){let{hierarchy:a,showBranchLenEffective:c,collapsed:l,blockSize:u,marginLeft:d}=n,A=s??u;Rc(a,f=>{let g=_c(f,c,o,i);if(g===void 0)return;let{data:h}=f,y=f.x,{id:E,name:x}=h;if(f.height>=1&&sg(y,r,A)){let S=l.includes(E);e.strokeStyle="black",e.fillStyle=S?"black":"white",e.beginPath(),e.arc(g,y,mi,0,2*Math.PI),e.fill(),e.stroke(),S||t?.insert({minX:g-mi+d,maxX:g-mi+ig+d,minY:y-mi,maxY:y-mi+ig,branch:!0,id:E,name:x})}})}function K4({theme:e,model:t,offsetY:r,ctx:n,clickMap:o,maxBranchLen:i,maxDepthToLeaf:s,blockSizeYOverride:a}){let{fontSize:c,showBranchLenEffective:l,treeMetadata:u,blockSize:d,labelsAlignRight:A,drawTree:f,treeAreaWidth:g,treeAreaWidthMinusMargin:h,marginLeft:y,noTree:E,labelWidthMap:x,collapsed:S}=t,w=Os({model:t,offsetY:r,blockSizeY:a??t.blockSize}),I=a??d,v=n.measureText("M").width;A?(n.textAlign="right",n.setLineDash([1,3]),n.strokeStyle=e.palette.text.primary):n.textAlign="start";for(let B of w){let{data:{name:R,id:D}}=B,L=B.x,F=u[R]?.genome||R;if(!(S.includes(D)&&R===D)&&sg(L,r,I)){let M=L+c/4,k=0;E||(k=_c(B,l,i,s)??0);let G=x.get(R)??n.measureText(F).width;if(n.fillStyle=e.palette.text.primary,A){let oe=h-2;f&&!E&&(n.beginPath(),n.moveTo(k+mi+2,L),n.lineTo(oe-2-G,L),n.stroke()),n.fillText(F,oe,M),o?.insert({minX:g-G,maxX:g,minY:M-v,maxY:M,name:R,id:D})}else{let j=E?2:k+ig;n.fillText(F,j,M),o?.insert({minX:j+y,maxX:j+G+y,minY:M-v,maxY:M,name:R,id:D})}}}n.setLineDash([])}function pf({model:e,clickMap:t,ctx:r,offsetY:n,theme:o,highResScaleFactorOverride:i,blockSizeYOverride:s}){t?.clear();let{noTree:a,drawTree:c,drawNodeBubbles:l,highResScaleFactor:u,fontSize:d,showTreeText:A,marginLeft:f,rowHeight:g}=e;r.resetTransform();let h=i??u;r.scale(h,h),r.translate(f,-n),bn(r,d);let{maxBranchLength:y,maxDepthToLeaf:E}=e;!a&&c&&(q4({ctx:r,offsetY:n,model:e,theme:o,maxBranchLen:y,maxDepthToLeaf:E,blockSizeYOverride:s}),z4({ctx:r,clickMap:t,offsetY:n,model:e,theme:o,maxBranchLen:y,maxDepthToLeaf:E,blockSizeYOverride:s}),l&&J4({ctx:r,offsetY:n,clickMap:t,model:e,maxBranchLen:y,maxDepthToLeaf:E,blockSizeYOverride:s})),A&&K4({ctx:r,offsetY:n,model:e,clickMap:t,theme:o,maxBranchLen:y,maxDepthToLeaf:E,blockSizeYOverride:s}),t?.finish()}var mf,RI,mi,ig,gf=m(()=>{og();Gs();of();mf=600,RI=5,mi=2.5,ig=mi*2});var kI={};Bt(kI,{Context:()=>lg});function QI(e){return!e||typeof e=="string"?e:e+""}function Yr(e,t){let r=Object.keys(t);for(let n of r)e=e.replace(new RegExp("\\{"+n+"\\}","gi"),t[n]);return e}function ag(e){if(!e)throw new Error("cannot create a random attribute name for an undefined object");let t="ABCDEFGHIJKLMNOPQRSTUVWXTZabcdefghiklmnopqrstuvwxyz",r="";do{r="";for(let n=0;n<12;n++)r+=t[Math.floor(Math.random()*t.length)]}while(e[r]);return r}function X4(e,t=10){let r={},n=e.split(",");for(let o=0;o<n.length;o+=2){let i="&"+n[o+1]+";",s=parseInt(n[o],t);r[i]="&#"+s+";"}return r["\\xa0"]="&#160;",r}function Z4(e){let t={left:"start",right:"end",center:"middle",start:"start",end:"end"};return t[e]||t.start}function eG(e){let t={alphabetic:"alphabetic",hanging:"hanging",top:"text-before-edge",bottom:"text-after-edge",middle:"central"};return t[e]||t.alphabetic}var _I,kc,Dc,cg,lg,DI=m(()=>{_I=X4("50,nbsp,51,iexcl,52,cent,53,pound,54,curren,55,yen,56,brvbar,57,sect,58,uml,59,copy,5a,ordf,5b,laquo,5c,not,5d,shy,5e,reg,5f,macr,5g,deg,5h,plusmn,5i,sup2,5j,sup3,5k,acute,5l,micro,5m,para,5n,middot,5o,cedil,5p,sup1,5q,ordm,5r,raquo,5s,frac14,5t,frac12,5u,frac34,5v,iquest,60,Agrave,61,Aacute,62,Acirc,63,Atilde,64,Auml,65,Aring,66,AElig,67,Ccedil,68,Egrave,69,Eacute,6a,Ecirc,6b,Euml,6c,Igrave,6d,Iacute,6e,Icirc,6f,Iuml,6g,ETH,6h,Ntilde,6i,Ograve,6j,Oacute,6k,Ocirc,6l,Otilde,6m,Ouml,6n,times,6o,Oslash,6p,Ugrave,6q,Uacute,6r,Ucirc,6s,Uuml,6t,Yacute,6u,THORN,6v,szlig,70,agrave,71,aacute,72,acirc,73,atilde,74,auml,75,aring,76,aelig,77,ccedil,78,egrave,79,eacute,7a,ecirc,7b,euml,7c,igrave,7d,iacute,7e,icirc,7f,iuml,7g,eth,7h,ntilde,7i,ograve,7j,oacute,7k,ocirc,7l,otilde,7m,ouml,7n,divide,7o,oslash,7p,ugrave,7q,uacute,7r,ucirc,7s,uuml,7t,yacute,7u,thorn,7v,yuml,ci,fnof,sh,Alpha,si,Beta,sj,Gamma,sk,Delta,sl,Epsilon,sm,Zeta,sn,Eta,so,Theta,sp,Iota,sq,Kappa,sr,Lambda,ss,Mu,st,Nu,su,Xi,sv,Omicron,t0,Pi,t1,Rho,t3,Sigma,t4,Tau,t5,Upsilon,t6,Phi,t7,Chi,t8,Psi,t9,Omega,th,alpha,ti,beta,tj,gamma,tk,delta,tl,epsilon,tm,zeta,tn,eta,to,theta,tp,iota,tq,kappa,tr,lambda,ts,mu,tt,nu,tu,xi,tv,omicron,u0,pi,u1,rho,u2,sigmaf,u3,sigma,u4,tau,u5,upsilon,u6,phi,u7,chi,u8,psi,u9,omega,uh,thetasym,ui,upsih,um,piv,812,bull,816,hellip,81i,prime,81j,Prime,81u,oline,824,frasl,88o,weierp,88h,image,88s,real,892,trade,89l,alefsym,8cg,larr,8ch,uarr,8ci,rarr,8cj,darr,8ck,harr,8dl,crarr,8eg,lArr,8eh,uArr,8ei,rArr,8ej,dArr,8ek,hArr,8g0,forall,8g2,part,8g3,exist,8g5,empty,8g7,nabla,8g8,isin,8g9,notin,8gb,ni,8gf,prod,8gh,sum,8gi,minus,8gn,lowast,8gq,radic,8gt,prop,8gu,infin,8h0,ang,8h7,and,8h8,or,8h9,cap,8ha,cup,8hb,int,8hk,there4,8hs,sim,8i5,cong,8i8,asymp,8j0,ne,8j1,equiv,8j4,le,8j5,ge,8k2,sub,8k3,sup,8k4,nsub,8k6,sube,8k7,supe,8kl,oplus,8kn,otimes,8l5,perp,8m5,sdot,8o8,lceil,8o9,rceil,8oa,lfloor,8ob,rfloor,8p9,lang,8pa,rang,9ea,loz,9j0,spades,9j3,clubs,9j5,hearts,9j6,diams,ai,OElig,aj,oelig,b0,Scaron,b1,scaron,bo,Yuml,m6,circ,ms,tilde,802,ensp,803,emsp,809,thinsp,80c,zwnj,80d,zwj,80e,lrm,80f,rlm,80j,ndash,80k,mdash,80o,lsquo,80p,rsquo,80q,sbquo,80s,ldquo,80t,rdquo,80u,bdquo,810,dagger,811,Dagger,81g,permil,81p,lsaquo,81q,rsaquo,85c,euro",32),kc={strokeStyle:{svgAttr:"stroke",canvas:"#000000",svg:"none",apply:"stroke"},fillStyle:{svgAttr:"fill",canvas:"#000000",svg:null,apply:"fill"},lineCap:{svgAttr:"stroke-linecap",canvas:"butt",svg:"butt",apply:"stroke"},lineJoin:{svgAttr:"stroke-linejoin",canvas:"miter",svg:"miter",apply:"stroke"},miterLimit:{svgAttr:"stroke-miterlimit",canvas:10,svg:4,apply:"stroke"},lineWidth:{svgAttr:"stroke-width",canvas:1,svg:1,apply:"stroke"},globalAlpha:{svgAttr:"opacity",canvas:1,svg:1,apply:"fill stroke"},font:{canvas:"10px sans-serif"},shadowColor:{canvas:"#000000"},shadowOffsetX:{canvas:0},shadowOffsetY:{canvas:0},shadowBlur:{canvas:0},textAlign:{canvas:"start"},textBaseline:{canvas:"alphabetic"},lineDash:{svgAttr:"stroke-dasharray",canvas:[],svg:null,apply:"stroke"}},Dc=class{__root;__ctx;constructor(t,r){this.__root=t,this.__ctx=r}addColorStop(t,r){let n=this.__ctx.__createElement("stop");if(n.setAttribute("offset",String(t)),QI(r).includes("rgba")){let i=/rgba\(\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d?\.?\d*)\s*\)/gi.exec(r);i&&(n.setAttribute("stop-color",Yr("rgb({r},{g},{b})",{r:i[1],g:i[2],b:i[3]})),n.setAttribute("stop-opacity",i[4]))}else n.setAttribute("stop-color",QI(r));this.__root.appendChild(n)}},cg=class{__root;__ctx;constructor(t,r){this.__root=t,this.__ctx=r}},lg=class{width;height;enableMirroring;canvas;__document;__ctx;__canvas;__root;__ids;__defs;__currentElement;__styleStack;__groupStack;__currentDefaultPath;__currentPosition;__transformMatrix;__transformMatrixStack;__currentElementsToStyle;__options;__id;__fontUnderline;__fontHref;strokeStyle;fillStyle;lineCap;lineJoin;miterLimit;lineWidth;globalAlpha;font;shadowColor;shadowOffsetX;shadowOffsetY;shadowBlur;textAlign;textBaseline;lineDash;constructor(t,r){let n={width:500,height:500,enableMirroring:!1},o;typeof t=="number"&&r!==void 0?o={...n,width:t,height:r}:t&&typeof t=="object"?o=t:o=n,this.width=o.width||n.width,this.height=o.height||n.height,this.enableMirroring=o.enableMirroring!==void 0?o.enableMirroring:n.enableMirroring,this.canvas=this,this.__document=o.document||document,o.ctx?this.__ctx=o.ctx:(this.__canvas=this.__document.createElement("canvas"),this.__ctx=this.__canvas.getContext("2d")),this.__setDefaultStyles(),this.__styleStack=[this.__getStyleState()],this.__groupStack=[],this.__root=this.__document.createElementNS("http://www.w3.org/2000/svg","svg"),this.__root.setAttribute("version","1.1"),this.__root.setAttribute("xmlns","http://www.w3.org/2000/svg"),this.__root.setAttributeNS("http://www.w3.org/2000/xmlns/","xmlns:xlink","http://www.w3.org/1999/xlink"),this.__root.setAttribute("width",String(this.width)),this.__root.setAttribute("height",String(this.height)),this.__ids={},this.__defs=this.__document.createElementNS("http://www.w3.org/2000/svg","defs"),this.__root.appendChild(this.__defs),this.__currentElement=this.__document.createElementNS("http://www.w3.org/2000/svg","g"),this.__root.appendChild(this.__currentElement),this.__currentDefaultPath="",this.__currentPosition={},this.__transformMatrix=new DOMMatrix,this.resetTransform(),this.__options=o,this.__id=Math.random().toString(16).substring(2,8)}__createElement(t,r={},n){let o=this.__document.createElementNS("http://www.w3.org/2000/svg",t);n&&(o.setAttribute("fill","none"),o.setAttribute("stroke","none"));for(let i of Object.keys(r))o.setAttribute(i,r[i]);return o}__setDefaultStyles(){for(let t of Object.keys(kc))this[t]=kc[t].canvas}__applyStyleState(t){for(let r of Object.keys(t))this[r]=t[r]}__getStyleState(){let t={};for(let r of Object.keys(kc))t[r]=this[r];return t}__applyTransformation(t,r){let{a:n,b:o,c:i,d:s,e:a,f:c}=r||this.getTransform();t.setAttribute("transform",`matrix(${n} ${o} ${i} ${s} ${a} ${c})`)}__applyStyleToCurrentElement(t){let r=this.__currentElement,n=this.__currentElementsToStyle;if(n){r.setAttribute(t,""),r=n.element;for(let i of n.children)i.setAttribute(t,"")}let o=Object.keys(kc);for(let i of o){let s=kc[i],a=this[i];if(s.apply){if(a instanceof cg){if(a.__ctx)for(let c of Array.from(a.__ctx.__defs.childNodes)){let l=c.getAttribute("id");l&&(this.__ids[l]=l,this.__defs.appendChild(c))}r.setAttribute(s.apply,Yr("url(#{id})",{id:a.__root.getAttribute("id")}))}else if(a instanceof Dc)r.setAttribute(s.apply,Yr("url(#{id})",{id:a.__root.getAttribute("id")}));else if(s.apply.includes(t)&&s.svg!==a)if((s.svgAttr==="stroke"||s.svgAttr==="fill")&&a&&a.includes("rgba")){let l=/rgba\(\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d?\.?\d*)\s*\)/gi.exec(a);if(l){r.setAttribute(s.svgAttr,Yr("rgb({r},{g},{b})",{r:l[1],g:l[2],b:l[3]}));let u=Number(l[4]),d=this.globalAlpha;d!=null&&(u*=d),r.setAttribute(s.svgAttr+"-opacity",String(u))}}else{let c=s.svgAttr,l=a;if(i==="globalAlpha"){if(c=t+"-"+s.svgAttr,r.getAttribute(c))continue}else if(i==="lineWidth"){let u=this.__getTransformScale();l=a*Math.max(u.x,u.y)}r.setAttribute(c,l)}}}}__closestGroupOrSvg(t){return t=t||this.__currentElement,t.nodeName==="g"||t.nodeName==="svg"?t:this.__closestGroupOrSvg(t.parentNode)}getSerializedSvg(t){let r=new XMLSerializer().serializeToString(this.__root);if(/xmlns="http:\/\/www\.w3\.org\/2000\/svg".+xmlns="http:\/\/www\.w3\.org\/2000\/svg/gi.test(r)&&(r=r.replace('xmlns="http://www.w3.org/2000/svg','xmlns:xlink="http://www.w3.org/1999/xlink')),t)for(let o of Object.keys(_I)){let i=new RegExp(o,"gi");i.test(r)&&(r=r.replace(i,_I[o]))}return r}getSvg(){return this.__root}save(){let t=this.__createElement("g"),r=this.__closestGroupOrSvg();this.__groupStack.push(r),r.appendChild(t),this.__currentElement=t;let n=this.__getStyleState();this.__styleStack.push(n),this.__transformMatrixStack||(this.__transformMatrixStack=[]),this.__transformMatrixStack.push(this.getTransform())}restore(){this.__currentElement=this.__groupStack.pop(),this.__currentElementsToStyle=void 0,this.__currentElement||(this.__currentElement=this.__root.childNodes[1]);let t=this.__styleStack.pop();this.__applyStyleState(t),this.__transformMatrixStack&&this.__transformMatrixStack.length>0&&this.setTransform(this.__transformMatrixStack.pop())}beginPath(){this.__currentDefaultPath="",this.__currentPosition={};let t=this.__createElement("path",{},!0);this.__closestGroupOrSvg().appendChild(t),this.__currentElement=t}__applyCurrentDefaultPath(){let t=this.__currentElement;t.nodeName==="path"&&t.setAttribute("d",this.__currentDefaultPath)}__addPathCommand(t){this.__currentDefaultPath+=" ",this.__currentDefaultPath+=t}moveTo(t,r){this.__currentElement.nodeName!=="path"&&this.beginPath(),this.__currentPosition={x:t,y:r},this.__addPathCommand(Yr("M {x} {y}",{x:this.__matrixTransform(t,r).x,y:this.__matrixTransform(t,r).y}))}closePath(){this.__currentDefaultPath&&this.__addPathCommand("Z")}lineTo(t,r){this.__currentPosition={x:t,y:r},this.__currentDefaultPath.includes("M")?this.__addPathCommand(Yr("L {x} {y}",{x:this.__matrixTransform(t,r).x,y:this.__matrixTransform(t,r).y})):this.__addPathCommand(Yr("M {x} {y}",{x:this.__matrixTransform(t,r).x,y:this.__matrixTransform(t,r).y}))}bezierCurveTo(t,r,n,o,i,s){this.__currentPosition={x:i,y:s},this.__addPathCommand(Yr("C {cp1x} {cp1y} {cp2x} {cp2y} {x} {y}",{cp1x:this.__matrixTransform(t,r).x,cp1y:this.__matrixTransform(t,r).y,cp2x:this.__matrixTransform(n,o).x,cp2y:this.__matrixTransform(n,o).y,x:this.__matrixTransform(i,s).x,y:this.__matrixTransform(i,s).y}))}quadraticCurveTo(t,r,n,o){this.__currentPosition={x:n,y:o},this.__addPathCommand(Yr("Q {cpx} {cpy} {x} {y}",{cpx:this.__matrixTransform(t,r).x,cpy:this.__matrixTransform(t,r).y,x:this.__matrixTransform(n,o).x,y:this.__matrixTransform(n,o).y}))}stroke(){this.__currentElement.nodeName==="path"&&this.__currentElement.setAttribute("paint-order","fill stroke markers"),this.__applyCurrentDefaultPath(),this.__applyStyleToCurrentElement("stroke")}fill(){this.__currentElement.nodeName==="path"&&this.__currentElement.setAttribute("paint-order","stroke fill markers"),this.__applyCurrentDefaultPath(),this.__applyStyleToCurrentElement("fill")}rect(t,r,n,o){this.__currentElement.nodeName!=="path"&&this.beginPath(),this.moveTo(t,r),this.lineTo(t+n,r),this.lineTo(t+n,r+o),this.lineTo(t,r+o),this.lineTo(t,r),this.closePath()}__clearCanvas(){let t=this.__root.childNodes[1];this.__root.removeChild(t),this.__currentElement=this.__document.createElementNS("http://www.w3.org/2000/svg","g"),this.__root.appendChild(this.__currentElement),this.__groupStack=[]}fillRect(t,r,n,o){let{a:i,b:s,c:a,d:c,e:l,f:u}=this.getTransform();JSON.stringify([i,s,a,c,l,u])===JSON.stringify([1,0,0,1,0,0])&&t===0&&r===0&&n===this.width&&o===this.height&&this.__clearCanvas();let d=this.__createElement("rect",{x:t,y:r,width:n,height:o},!0);this.__closestGroupOrSvg().appendChild(d),this.__currentElement=d,this.__applyTransformation(d),this.__applyStyleToCurrentElement("fill")}strokeRect(t,r,n,o){let i=this.__createElement("rect",{x:t,y:r,width:n,height:o},!0);this.__closestGroupOrSvg().appendChild(i),this.__currentElement=i,this.__applyTransformation(i),this.__applyStyleToCurrentElement("stroke")}clearRect(t,r,n,o){let{a:i,b:s,c:a,d:c,e:l,f:u}=this.getTransform();if(JSON.stringify([i,s,a,c,l,u])===JSON.stringify([1,0,0,1,0,0])&&t===0&&r===0&&n===this.width&&o===this.height){this.__clearCanvas();return}let d=this.__createElement("rect",{x:t,y:r,width:n,height:o,fill:"#FFFFFF"},!0);this.__applyTransformation(d),this.__closestGroupOrSvg().appendChild(d)}createLinearGradient(t,r,n,o){let i=this.__createElement("linearGradient",{id:ag(this.__ids),x1:t+"px",x2:n+"px",y1:r+"px",y2:o+"px",gradientUnits:"userSpaceOnUse"});return this.__defs.appendChild(i),new Dc(i,this)}createRadialGradient(t,r,n,o,i,s){let a=this.__createElement("radialGradient",{id:ag(this.__ids),cx:o+"px",cy:i+"px",r:s+"px",fx:t+"px",fy:r+"px",gradientUnits:"userSpaceOnUse"});return this.__defs.appendChild(a),new Dc(a,this)}__applyText(t,r,n,o){let i=document.createElement("span");i.setAttribute("style","font:"+this.font);let s=i.style,a=this.__closestGroupOrSvg(),c=this.__createElement("text",{"font-family":s.fontFamily,"font-size":s.fontSize,"font-style":s.fontStyle,"font-weight":s.fontWeight,"text-decoration":this.__fontUnderline,x:r,y:n,"text-anchor":Z4(this.textAlign),"dominant-baseline":eG(this.textBaseline)},!0);c.appendChild(this.__document.createTextNode(t)),this.__currentElement=c,this.__applyTransformation(c),this.__applyStyleToCurrentElement(o);let l=c;if(this.__fontHref){let u=this.__createElement("a");u.setAttributeNS("http://www.w3.org/1999/xlink","xlink:href",this.__fontHref),u.appendChild(c),l=u}a.appendChild(l)}fillText(t,r,n){this.__applyText(t,r,n,"fill")}strokeText(t,r,n){this.__applyText(t,r,n,"stroke")}measureText(t){return this.__ctx.font=this.font,this.__ctx.measureText(t)}arc(t,r,n,o,i,s){if(o===i)return;o=o%(2*Math.PI),i=i%(2*Math.PI),o===i&&(i=(i+2*Math.PI-.001*(s?-1:1))%(2*Math.PI));let a=t+n*Math.cos(i),c=r+n*Math.sin(i),l=t+n*Math.cos(o),u=r+n*Math.sin(o),d=s?0:1,A=0,f=i-o;f<0&&(f+=2*Math.PI),s?A=f>Math.PI?0:1:A=f>Math.PI?1:0;let g=Math.hypot(this.__transformMatrix.a,this.__transformMatrix.b),h=Math.hypot(this.__transformMatrix.c,this.__transformMatrix.d);this.lineTo(l,u),this.__addPathCommand(Yr("A {rx} {ry} {xAxisRotation} {largeArcFlag} {sweepFlag} {endX} {endY}",{rx:n*g,ry:n*h,xAxisRotation:0,largeArcFlag:A,sweepFlag:d,endX:this.__matrixTransform(a,c).x,endY:this.__matrixTransform(a,c).y})),this.__currentPosition={x:a,y:c}}clip(){let t=this.__closestGroupOrSvg(),r=this.__createElement("clipPath"),n=ag(this.__ids),o=this.__createElement("g");this.__applyCurrentDefaultPath(),t.removeChild(this.__currentElement),r.setAttribute("id",n),r.appendChild(this.__currentElement),this.__defs.appendChild(r),t.setAttribute("clip-path",Yr("url(#{id})",{id:n})),t.appendChild(o),this.__currentElement=o}setLineDash(t){t&&t.length>0?this.lineDash=t.join(","):this.lineDash=null}setTransform(t,r,n,o,i,s){t instanceof DOMMatrix?this.__transformMatrix=new DOMMatrix([t.a,t.b,t.c,t.d,t.e,t.f]):this.__transformMatrix=new DOMMatrix([t,r,n,o,i,s])}getTransform(){let{a:t,b:r,c:n,d:o,e:i,f:s}=this.__transformMatrix;return new DOMMatrix([t,r,n,o,i,s])}resetTransform(){this.setTransform(1,0,0,1,0,0)}scale(t,r){if(r===void 0&&(r=t),isNaN(t)||isNaN(r)||!isFinite(t)||!isFinite(r))return;let n=this.getTransform().scale(t,r);this.setTransform(n)}rotate(t){let r=this.getTransform().multiply(new DOMMatrix([Math.cos(t),Math.sin(t),-Math.sin(t),Math.cos(t),0,0]));this.setTransform(r)}translate(t,r){let n=this.getTransform().translate(t,r);this.setTransform(n)}transform(t,r,n,o,i,s){let a=this.getTransform().multiply(new DOMMatrix([t,r,n,o,i,s]));this.setTransform(a)}__matrixTransform(t,r){return new DOMPoint(t,r).matrixTransform(this.__transformMatrix)}__getTransformScale(){return{x:Math.hypot(this.__transformMatrix.a,this.__transformMatrix.b),y:Math.hypot(this.__transformMatrix.c,this.__transformMatrix.d)}}__getTransformRotation(){return Math.atan2(this.__transformMatrix.b,this.__transformMatrix.a)}drawFocusRing(){}createImageData(){}putImageData(){}globalCompositeOperation(){}drawImage(){}createPattern(){return null}}});var OI={};Bt(OI,{renderToSvg:()=>FI});function nG(e){let t=e.visibleDomainTypes.map(o=>o.name),r=Math.max(0,...t.map(o=>o.length)),n=Nc*2+Lc+6+r*rG;return Math.min(360,Math.max(120,n))}function oG(e,t){let{width:r,height:n,scrollX:o,scrollY:i,totalWidth:s,totalHeight:a,treeAreaWidth:c,totalTrackAreaHeight:l,minimapHeight:u}=e,d=t.includeTracks?l:0,A=t.exportType==="viewport"&&!!t.includeMinimap,f=e.actuallyShowDomains&&e.visibleDomainTypes.length>0?nG(e):0;return t.exportType==="entire"?{width:s+c,height:a+d,contentHeight:a,trackHeight:d,offsetX:0,offsetY:0,includeMinimap:A,legendWidth:f}:{width:r,height:n+(A?u:0)+d,contentHeight:n,trackHeight:d,offsetX:-o,offsetY:-i,includeMinimap:A,legendWidth:f}}async function FI(e,t){await(0,PI.when)(()=>e.dataInitialized);let{Context:r}=await Promise.resolve().then(()=>(DI(),kI));return(0,LI.renderToStaticMarkup)(ie.default.createElement(iG,{model:e,theme:t.theme,Context:r,layout:oG(e,t)}))}function iG({model:e,theme:t,Context:r,layout:n}){let{width:o,height:i,trackHeight:s,includeMinimap:a,legendWidth:c}=n,{treeAreaWidth:l,minimapHeight:u}=e,d=o+c,A=a?u:0,f=ie.default.createElement(ie.default.Fragment,null,s>0?ie.default.createElement(cG,{Context:r,model:e,theme:t,layout:n}):null,ie.default.createElement("g",{transform:s>0?`translate(0 ${s})`:void 0},ie.default.createElement(aG,{Context:r,model:e,theme:t,layout:n})));return ie.default.createElement("svg",{width:d,height:i,xmlns:"http://www.w3.org/2000/svg",xmlnsXlink:"http://www.w3.org/1999/xlink",viewBox:`0 0 ${d} ${i}`},ie.default.createElement("rect",{width:"100%",height:"100%",fill:"white"}),a?ie.default.createElement(ie.default.Fragment,null,ie.default.createElement("g",{transform:`translate(${l} 0)`},ie.default.createElement(jw,{model:e})),ie.default.createElement("g",{transform:`translate(0 ${u})`},f)):f,c>0?ie.default.createElement("g",{transform:`translate(${o} ${A})`},ie.default.createElement(sG,{model:e,width:c})):null)}function sG({model:e,width:t}){let{visibleDomainTypes:r,fillPalette:n,strokePalette:o}=e,i=Nc*2+r.length*NI;return ie.default.createElement("g",null,ie.default.createElement("rect",{x:0,y:0,width:t-4,height:i,fill:"white",stroke:"#ccc",rx:2}),r.map((s,a)=>{let c=Nc+a*NI;return ie.default.createElement("g",{key:s.accession},ie.default.createElement("rect",{x:Nc,y:c,width:Lc,height:Lc,fill:n[s.accession],stroke:o[s.accession]}),ie.default.createElement("text",{x:Nc+Lc+6,y:c+Lc-1,fontSize:tG},s.name))}))}function aG({model:e,theme:t,layout:r,Context:n}){let{contentHeight:o,offsetX:i,offsetY:s,width:a}=r,{treeAreaWidth:c,colorScheme:l,id:u}=e,d=a-c,A=Bc(l,t),f=new n(c,o);pf({model:e,theme:t,ctx:f,offsetY:s,blockSizeYOverride:o,highResScaleFactorOverride:1});let g=new n(d,o);return sf({model:e,ctx:g,offsetX:i,offsetY:s,blockSizeYOverride:o,highResScaleFactorOverride:1}),ff({model:e,theme:t,ctx:g,contrastScheme:A,offsetX:i,offsetY:s,blockSizeXOverride:d,blockSizeYOverride:o,highResScaleFactorOverride:1}),ie.default.createElement(ie.default.Fragment,null,ie.default.createElement(ug,{clipId:`tree-${u}`,width:c,height:o,ctx:f}),ie.default.createElement(ug,{clipId:`msa-${u}`,width:d,height:o,transform:`translate(${c} 0)`,ctx:g}))}function cG({model:e,theme:t,layout:r,Context:n}){let{trackHeight:o,offsetX:i,width:s}=r,{treeAreaWidth:a,colorScheme:c,id:l}=e,u=s-a,d=Bc(c,t),A=new n(u,o);return xI({model:e,ctx:A,contrastScheme:d,theme:t,offsetX:i,blockSizeXOverride:u,highResScaleFactorOverride:1}),ie.default.createElement("g",{transform:`translate(${a} 0)`},ie.default.createElement(ug,{clipId:`tracks-${l}`,width:u,height:o,ctx:A}))}function ug({clipId:e,width:t,height:r,transform:n,ctx:o}){return ie.default.createElement(ie.default.Fragment,null,ie.default.createElement("defs",null,ie.default.createElement("clipPath",{id:e},ie.default.createElement("rect",{x:0,y:0,width:t,height:r}))),ie.default.createElement("g",{clipPath:`url(#${e})`,transform:n,dangerouslySetInnerHTML:{__html:o.getSvg().innerHTML}}))}var ie,LI,PI,Nc,NI,Lc,tG,rG,fg=m(()=>{ie=p(Q(),1),LI=p(we(),1),PI=p(Ps(),1);$w();Up();Zp();df();gf();Co();Nc=8,NI=16,Lc=12,tG=12,rG=7});var Ze=K((Fee,GI)=>{GI.exports=JBrowseExports["@jbrowse/core/ui"]});var UI,HI,Hs,dg=m(()=>{UI=p(O(),1),HI=p(Q(),1),Hs=class extends HI.Component{constructor(t){super(t),this.state={error:void 0}}componentDidCatch(t,r){console.error("ErrorBoundary caught an error:",t,r),this.setState({error:t})}render(){return this.state.error?(0,UI.jsx)(this.props.FallbackComponent,{error:this.state.error}):this.props.children}}});var U=K((Gee,VI)=>{VI.exports=JBrowseExports["@mui/material"]});function bo(e,t){let r=(0,Vs.useRef)(!1),[n,o]=(0,Vs.useState)();return(0,Vs.useEffect)(()=>{if(n!==void 0){let a=function(l){r.current||(r.current=!0,requestAnimationFrame(()=>{let u=e==="x"?l.clientX:l.clientY;t(u-i,s),r.current=!1}))},c=function(){o(void 0)},{client:i,startScroll:s}=n;return document.addEventListener("mousemove",a),document.addEventListener("mouseup",c),()=>{document.removeEventListener("mousemove",a),document.removeEventListener("mouseup",c)}}},[e,t,n]),{dragging:n!==void 0,startDrag:(i,s)=>{o({client:e==="x"?i.clientX:i.clientY,startScroll:s})}}}var Vs,hf=m(()=>{Vs=p(Q(),1)});var Br,yf,Ag,mg,jI,$I,WI,pg=m(()=>{Br=p(Q(),1),yf=p(W(),1);hf();Ag="rgba(200,200,200)",mg="rgba(150,150,150)",jI=(0,yf.observer)(function({model:e}){let{resizeHandleWidth:t}=e,[r,n]=(0,Br.useState)(!1),{startDrag:o}=bo("x",(0,Br.useCallback)((i,s)=>{e.setTreeAreaWidth(s+i)},[e]));return Br.default.createElement("div",{onMouseDown:i=>{o(i,e.treeAreaWidth)},onMouseEnter:()=>{n(!0)},onMouseLeave:()=>{n(!1)},style:{cursor:"ew-resize",width:t,background:r?mg:Ag,position:"relative"}})}),$I=(0,yf.observer)(function({model:e}){let{resizeHandleWidth:t}=e,[r,n]=(0,Br.useState)(!1),{startDrag:o}=bo("y",(0,Br.useCallback)((i,s)=>{e.setHeight(s+i)},[e]));return Br.default.createElement("div",{onMouseDown:i=>{o(i,e.height)},onMouseEnter:()=>{n(!0)},onMouseLeave:()=>{n(!1)},style:{cursor:"ns-resize",width:"100%",height:t,background:r?mg:Ag,position:"relative"}})}),WI=(0,yf.observer)(function({model:e}){let{resizeHandleWidth:t}=e,[r,n]=(0,Br.useState)(!1),{startDrag:o}=bo("y",(0,Br.useCallback)((i,s)=>{e.setConservationTrackHeight(Math.max(10,s+i))},[e]));return Br.default.createElement("div",{onMouseDown:i=>{o(i,e.conservationTrackHeight)},onMouseEnter:()=>{n(!0)},onMouseLeave:()=>{n(!1)},style:{position:"absolute",bottom:0,left:0,cursor:"ns-resize",width:"100%",height:t,zIndex:1,background:r?mg:Ag}})})});var gg=K((jee,YI)=>{YI.exports=JBrowseExports["@mui/material/styles"]});var js,hg=m(()=>{js=e=>{let t=e.length,r=0,n="";for(;r<t;r++){let o=e[r];if(o==null)continue;let i;switch(typeof o){case"boolean":break;case"object":{if(Array.isArray(o))i=js(o);else{let s=o;i="";for(let a in s)s[a]&&a&&(i&&(i+=" "),i+=a)}break}default:i=o}i&&(n&&(n+=" "),n+=i)}return n}});function qI(e){return e instanceof Object&&!("styles"in e)&&!("length"in e)&&!("__emotion_styles"in e)}var zI=m(()=>{});function XI(e){let{useCache:t}=e;function r(){let n=t(),{css:o,cx:i}=(0,KI.useMemo)(()=>lG({cache:n}),[n]);return{css:o,cx:i}}return{useCssAndCx:r}}var KI,lG,JI,ZI=m(()=>{KI=p(Q(),1);oi();Bs();hg();zI();({createCssAndCx:lG}=(()=>{function e(r,n,o){let i=[],s=ri(r,i,o);return i.length<2?o:s+n(i)}function t(r){let{cache:n}=r,o=(...s)=>{let a=hn(s,n.registered);ni(n,a,!1);let c=`${n.key}-${a.name}`;e:{let l=s[0];if(!qI(l))break e;JI.saveClassNameCSSObjectMapping(n,c,l)}return c};return{css:o,cx:(...s)=>{let a=js(s),c=JI.fixClassName(n,a,o);return e(n.registered,o,c)}}}return{createCssAndCx:t}})());JI=(()=>{let e=new WeakMap;return{saveClassNameCSSObjectMapping:(t,r,n)=>{let o=e.get(t);o===void 0&&(o=new Map,e.set(t,o)),o.set(r,n)},fixClassName:(()=>{function t(r){let n=!1;return r.map(([o,i])=>{if(i===void 0)return o;let s;if(n)s={"&&":i};else{s=o;for(let a in i)if(a.startsWith("@media")){n=!0;break}}return s})}return(r,n,o)=>{if(!n.includes(" "))return n;let i=e.get(r);return js(t(n.split(" ").map(s=>[s,i?.get(s)])).map(s=>typeof s=="string"?s:o(s)))}})()}})()});function eS(e,t,r){if(!(t instanceof Object))return e;let n=Object.keys(t);if(n.length===0)return e;let o={};for(let i of Object.keys(e))o[i]=r(e[i],t[i]);for(let i of n){if(i in e)continue;let s=t[i];typeof s=="string"&&(o[i]=s)}return o}var tS=m(()=>{});function rS(e){if(!(e instanceof Object)||typeof e=="function")return e;let t=[];for(let r in e){let n=e[r],o=typeof n;if(!(o==="string"||o==="number"&&!isNaN(n)||o==="boolean"||n===void 0||n===null))return e;t.push(`${r}:${o}_${n}`)}return`xSqLiJdLMd9s${t.join("|")}`}var nS=m(()=>{});function oS(e){let{useTheme:t}=e,{useCssAndCx:r}=XI({useCache:uG});function n(){return function(o){let i=typeof o=="function"?o:()=>o;return function(a,c){let l=t(),{css:u,cx:d}=r(),A=(0,yg.useMemo)(()=>{let y=i(l),E={};for(let x of Object.keys(y)){let S=y[x];E[x]=u(S)}return E},[u,l]),f=c?.props.classes,g=rS(f);return{classes:(0,yg.useMemo)(()=>f?eS(A,f,d):A,[A,g,d]),theme:l,css:u,cx:d}}}}return{makeStyles:n}}var yg,uG,iS=m(()=>{"use client";yg=p(Q(),1);Ac();ZI();tS();nS();uG=Vm});var sS,Z,aS=m(()=>{sS=p(gg(),1);iS();({makeStyles:Z}=oS({useTheme:sS.useTheme}))});var cS=m(()=>{aS()});function xf(...e){return js(e)}var Ve=m(()=>{"use client";Ac();cS();hg()});var lS,uS,fS=m(()=>{"use client";Ie();lS=p(O(),1),uS=Y((0,lS.jsx)("path",{d:"m7 10 5 5 5-5z"}),"ArrowDropDown")});function dS(e,t){return t===1?e*16:t===2?e*100:e}function AS(e){let t=Math.abs(e);return t<6?25:t>150?500:t>30?150:75}function mS(e,t){let r=fG*t,n=Math.max(-r,Math.min(r,e));return n>0?1/(1+n):1-n}var fG,pS=m(()=>{fG=.011997600479904018});function $s({ref:e,onScrollX:t,onScrollY:r,onZoom:n,scrollZoom:o}){let i=(0,Mt.useRef)(!1),s=(0,Mt.useRef)(!1),a=(0,Mt.useRef)(0),c=(0,Mt.useRef)(0),l=(0,Mt.useRef)(0),u=(0,Mt.useRef)(0),d=(0,Mt.useRef)(0),A=(0,Mt.useRef)(null),f=(0,Mt.useRef)(0),g=(0,Mt.useRef)(0),[h,y]=(0,Mt.useState)(!1);(0,Mt.useEffect)(()=>{let S=e.current;if(!S)return;function w(I){let v=I.ctrlKey||I.metaKey,B=o&&!I.shiftKey&&Math.abs(I.deltaY)>=Math.abs(I.deltaX);if(n&&(v||B)){let L=S.getBoundingClientRect(),F=dS(I.deltaY,I.deltaMode),C=v?AS(F):500;l.current+=F/C,u.current=I.clientX-L.left,d.current=I.clientY-L.top,s.current||(s.current=!0,requestAnimationFrame(M=>{let k=A.current===null?16.67:M-A.current;A.current=M,n(mS(l.current,Math.min(100,k)),u.current,d.current),l.current=0,s.current=!1})),I.preventDefault(),I.stopPropagation();return}let R=!!t&&I.deltaX!==0,D=!!r&&I.deltaY!==0;(R||D)&&(t&&(a.current+=I.deltaX),r&&(c.current+=I.deltaY),i.current||(i.current=!0,requestAnimationFrame(()=>{t&&(t(-a.current),a.current=0),r&&(r(-c.current),c.current=0),i.current=!1})),I.preventDefault(),I.stopPropagation())}return S.addEventListener("wheel",w,{passive:!1}),()=>{S.removeEventListener("wheel",w)}},[e,t,r,n,o]),(0,Mt.useEffect)(()=>{if(!h)return;function S(I){I.preventDefault();let v=I.clientX-f.current,B=I.clientY-g.current;(v&&t||B&&r)&&(i.current||(i.current=!0,requestAnimationFrame(()=>{t?.(v),r?.(B),i.current=!1,f.current=I.clientX,g.current=I.clientY})))}function w(){f.current=0,g.current=0,y(!1)}return window.addEventListener("mousemove",S,!0),window.addEventListener("mouseup",w,!0),()=>{window.removeEventListener("mousemove",S,!0),window.removeEventListener("mouseup",w,!0)}},[h,t,r]);function E(S){let w=S.target;w.draggable||w.dataset.resizer||S.button===0&&(f.current=S.clientX,g.current=S.clientY,y(!0))}function x(S){S.preventDefault(),y(!1)}return{onMouseDown:E,onMouseUp:x}}var Mt,Cf=m(()=>{Mt=p(Q(),1);pS()});function Pc(e){let t=navigator.clipboard;if(t?.writeText){t.writeText(e).catch(n=>{console.error("Failed to copy to clipboard:",n)});return}let r=document.createElement("textarea");r.value=e,r.style.position="fixed",r.style.opacity="0",document.body.append(r),r.select(),document.execCommand("copy"),r.remove()}var xg=m(()=>{});var yS={};Bt(yS,{default:()=>pG});var Wn,gS,pi,hS,AG,mG,pG,xS=m(()=>{Wn=p(Q(),1),gS=p(Ze(),1);Ve();pi=p(U(),1),hS=p(W(),1);xg();AG=Z()(e=>({textArea:{padding:e.spacing(2),overflow:"auto",background:"#ddd",wordBreak:"break-word"}})),mG=(0,hS.observer)(function({model:e,onClose:t}){let[r,n]=(0,Wn.useState)("Copy to clipboard"),{classes:o}=AG();return Wn.default.createElement(gS.Dialog,{open:!0,onClose:t,fullWidth:!0,maxWidth:"lg",title:`Track info - ${e.name}`},Wn.default.createElement(pi.DialogContent,null,Wn.default.createElement(pi.Button,{variant:"contained",color:"primary",onClick:()=>{Pc(e.data),n("Copied!"),setTimeout(()=>{n("Copy to clipboard")},300)}},r),Wn.default.createElement("pre",{className:o.textArea},e.data)),Wn.default.createElement(pi.DialogActions,null,Wn.default.createElement(pi.Button,{variant:"contained",onClick:t,color:"secondary"},"Close")))}),pG=mG});var et,gi,Cg,gG,hG,yG,xG,CS,bS=m(()=>{et=p(Q(),1);Ve();fS();gi=p(U(),1),Cg=p(W(),1);Cf();gG=(0,et.lazy)(()=>Promise.resolve().then(()=>(xS(),yS))),hG=Z()({button:{padding:0}}),yG=(0,Cg.observer)(function({model:t,track:r}){let[n,o]=(0,et.useState)(),i=()=>{o(void 0)},{drawLabels:s,fontSize:a,treeAreaWidth:c}=t,{model:{name:l,height:u}}=r,{classes:d}=hG(),A=Math.min(u,a);return et.default.createElement("div",{style:{width:c,height:u,flexShrink:0,textAlign:"right",fontSize:A}},s?l:""," ",et.default.createElement(gi.IconButton,{className:d.button,style:{width:A,height:A},onClick:f=>{o(f.currentTarget)}},et.default.createElement(uS,null)),n?et.default.createElement(gi.Menu,{anchorEl:n,transitionDuration:0,open:!0,onClose:()=>{i()}},et.default.createElement(gi.MenuItem,{dense:!0,onClick:()=>{t.toggleTrack(r.model.id),i()}},"Close"),et.default.createElement(gi.MenuItem,{dense:!0,onClick:()=>{t.queueDialog(f=>[gG,{onClose:f,model:r.model}]),i()}},"Get info")):null)}),xG=(0,Cg.observer)(function({model:e,track:t}){let{resizeHandleWidth:r,colWidth:n,scrollX:o,numColumns:i}=e,{model:{height:s}}=t,a=(0,et.useRef)(null),c=(0,et.useCallback)(l=>{e.doScrollX(l)},[e]);return $s({ref:a,onScrollX:c}),et.default.createElement("div",{style:{display:"flex",height:s}},et.default.createElement(yG,{model:e,track:t}),et.default.createElement("div",{style:{width:r,flexShrink:0}}),et.default.createElement("div",{ref:a,onMouseMove:l=>{if(!a.current)return;let{left:u}=a.current.getBoundingClientRect(),d=l.clientX-u-o,A=Math.floor(d/n);A>=0&&A<i?e.setMousePos(A,void 0):e.setMousePos(void 0,void 0)},onMouseLeave:()=>{e.setMousePos(void 0,void 0)}},et.default.createElement(t.ReactComponent,{model:e,track:t})))}),CS=xG});var hi,ES,wS,CG,IS,SS=m(()=>{hi=p(Q(),1),ES=p(we(),1),wS=p(W(),1);hf();CG=(0,wS.observer)(({model:e})=>{let{msaAreaHeight:t,scrollY:r,totalHeight:n}=e,[o,i]=(0,hi.useState)(!1),s="rgba(66, 119, 127, 0.3)",a=t/n,c=-r,l=c+t,u=c*a,d=l*a,{startDrag:A}=bo("y",(0,hi.useCallback)((f,g)=>{e.setScrollY((0,ES.clamp)(g-f/a,e.maxScrollY,0))},[e,a]));return hi.default.createElement("div",{style:{position:"relative",width:20,height:t,borderLeft:"1px solid #555",borderTop:"1px solid #555",boxSizing:"border-box"}},hi.default.createElement("div",{style:{position:"absolute",top:Math.max(0,u),left:0,background:o?"rgba(66,119,127,0.6)":s,cursor:"pointer",boxSizing:"border-box",width:20,height:Math.max(d-u,20),zIndex:100},onMouseOver:()=>{i(!0)},onMouseOut:()=>{i(!1)},onMouseDown:f=>{A(f,e.scrollY)}}))}),IS=CG});function bg(){let e=(0,Ws.useRef)(null),[t,r]=(0,Ws.useState)({width:void 0,height:void 0});return(0,Ws.useEffect)(()=>{if(!e.current)return;let n=typeof window<"u"&&"ResizeObserver"in window?window.ResizeObserver:void 0;if(!n)return;let o=new n(i=>{r({width:i[0].contentRect.width,height:i[0].contentRect.height})});return o.observe(e.current),()=>{o.disconnect()}},[]),[e,t]}var Ws,vS=m(()=>{Ws=p(Q(),1)});var BS,TS,MS=m(()=>{"use client";Ie();BS=p(O(),1),TS=Y((0,BS.jsx)("path",{d:"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m1 17h-2v-2h2zm2.07-7.75-.9.92C13.45 12.9 13 13.5 13 15h-2v-.5c0-1.1.45-2.1 1.17-2.83l1.24-1.26c.37-.36.59-.86.59-1.41 0-1.1-.9-2-2-2s-2 .9-2 2H8c0-2.21 1.79-4 4-4s4 1.79 4 4c0 .88-.36 1.68-.93 2.25"}),"Help")});var QS=K((Rte,RS)=>{RS.exports=JBrowseExports["@mui/material/utils"]});var Me,sr=m(()=>{"use client";Me=p(QS(),1)});var _S,kS,DS=m(()=>{"use client";sr();_S=p(O(),1),kS=(0,Me.createSvgIcon)((0,_S.jsx)("path",{d:"M10 6 8.59 7.41 13.17 12l-4.58 4.59L10 18l6-6z"}),"ChevronRight")});var NS,LS,PS=m(()=>{"use client";sr();NS=p(O(),1),LS=(0,Me.createSvgIcon)((0,NS.jsx)("path",{d:"M11 18h2v-2h-2zm1-16C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m0 18c-4.41 0-8-3.59-8-8s3.59-8 8-8 8 3.59 8 8-3.59 8-8 8m0-14c-2.21 0-4 1.79-4 4h2c0-1.1.9-2 2-2s2 .9 2 2c0 2-3 1.75-3 5h2c0-2.25 3-2.5 3-5 0-2.21-1.79-4-4-4"}),"HelpOutline")});var FS,bf,Eg=m(()=>{"use client";sr();FS=p(O(),1),bf=(0,Me.createSvgIcon)((0,FS.jsx)("path",{d:"M19 6.41 17.59 5 12 10.59 6.41 5 5 6.41 10.59 12 5 17.59 6.41 19 12 13.41 17.59 19 19 17.59 13.41 12z"}),"Close")});var OS,GS,US=m(()=>{"use client";sr();OS=p(O(),1),GS=(0,Me.createSvgIcon)((0,OS.jsx)("path",{d:"M17.65 6.35C16.2 4.9 14.21 4 12 4c-4.42 0-7.99 3.58-7.99 8s3.57 8 7.99 8c3.73 0 6.84-2.55 7.73-6h-2.08c-.82 2.33-3.04 4-5.65 4-3.31 0-6-2.69-6-6s2.69-6 6-6c1.66 0 3.14.69 4.22 1.78L13 11h7V4z"}),"Refresh")});var HS,VS,jS=m(()=>{"use client";sr();HS=p(O(),1),VS=(0,Me.createSvgIcon)((0,HS.jsx)("path",{d:"M15.73 3H8.27L3 8.27v7.46L8.27 21h7.46L21 15.73V8.27zM12 17.3c-.72 0-1.3-.58-1.3-1.3s.58-1.3 1.3-1.3 1.3.58 1.3 1.3-.58 1.3-1.3 1.3m1-4.3h-2V7h2z"}),"Report")});function wg({children:e}){let{classes:t}=bG();return(0,$S.jsx)("div",{className:t.bg,children:e})}var $S,bG,WS=m(()=>{$S=p(O(),1);Ve();bG=Z()(e=>({bg:{padding:4,margin:4,overflow:"auto",maxHeight:200,background:e.palette.mode==="dark"?"#833":"#f88",border:`1px solid ${e.palette.divider}`}}))});var qS=K(Ig=>{var YS="ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/".split("");Ig.encode=function(e){if(0<=e&&e<YS.length)return YS[e];throw new TypeError("Must be between 0 and 63: "+e)};Ig.decode=function(e){var t=65,r=90,n=97,o=122,i=48,s=57,a=43,c=47,l=26,u=52;return t<=e&&e<=r?e-t:n<=e&&e<=o?e-n+l:i<=e&&e<=s?e-i+u:e==a?62:e==c?63:-1}});var Bg=K(vg=>{var zS=qS(),Sg=5,JS=1<<Sg,KS=JS-1,XS=JS;function EG(e){return e<0?(-e<<1)+1:(e<<1)+0}function wG(e){var t=(e&1)===1,r=e>>1;return t?-r:r}vg.encode=function(t){var r="",n,o=EG(t);do n=o&KS,o>>>=Sg,o>0&&(n|=XS),r+=zS.encode(n);while(o>0);return r};vg.decode=function(t,r,n){var o=t.length,i=0,s=0,a,c;do{if(r>=o)throw new Error("Expected more digits in base 64 VLQ value.");if(c=zS.decode(t.charCodeAt(r++)),c===-1)throw new Error("Invalid base64 digit: "+t.charAt(r-1));a=!!(c&XS),c&=KS,i=i+(c<<s),s+=Sg}while(a);n.value=wG(i),n.rest=r}});var qs=K(dt=>{function IG(e,t,r){if(t in e)return e[t];if(arguments.length===3)return r;throw new Error('"'+t+'" is a required argument.')}dt.getArg=IG;var ZS=/^(?:([\w+\-.]+):)?\/\/(?:(\w+:\w+)@)?([\w.-]*)(?::(\d+))?(.*)$/,SG=/^data:.+\,.+$/;function Fc(e){var t=e.match(ZS);return t?{scheme:t[1],auth:t[2],host:t[3],port:t[4],path:t[5]}:null}dt.urlParse=Fc;function Ys(e){var t="";return e.scheme&&(t+=e.scheme+":"),t+="//",e.auth&&(t+=e.auth+"@"),e.host&&(t+=e.host),e.port&&(t+=":"+e.port),e.path&&(t+=e.path),t}dt.urlGenerate=Ys;var vG=32;function BG(e){var t=[];return function(r){for(var n=0;n<t.length;n++)if(t[n].input===r){var o=t[0];return t[0]=t[n],t[n]=o,t[0].result}var i=e(r);return t.unshift({input:r,result:i}),t.length>vG&&t.pop(),i}}var Tg=BG(function(t){var r=t,n=Fc(t);if(n){if(!n.path)return t;r=n.path}for(var o=dt.isAbsolute(r),i=[],s=0,a=0;;)if(s=a,a=r.indexOf("/",s),a===-1){i.push(r.slice(s));break}else for(i.push(r.slice(s,a));a<r.length&&r[a]==="/";)a++;for(var c,l=0,a=i.length-1;a>=0;a--)c=i[a],c==="."?i.splice(a,1):c===".."?l++:l>0&&(c===""?(i.splice(a+1,l),l=0):(i.splice(a,2),l--));return r=i.join("/"),r===""&&(r=o?"/":"."),n?(n.path=r,Ys(n)):r});dt.normalize=Tg;function e1(e,t){e===""&&(e="."),t===""&&(t=".");var r=Fc(t),n=Fc(e);if(n&&(e=n.path||"/"),r&&!r.scheme)return n&&(r.scheme=n.scheme),Ys(r);if(r||t.match(SG))return t;if(n&&!n.host&&!n.path)return n.host=t,Ys(n);var o=t.charAt(0)==="/"?t:Tg(e.replace(/\/+$/,"")+"/"+t);return n?(n.path=o,Ys(n)):o}dt.join=e1;dt.isAbsolute=function(e){return e.charAt(0)==="/"||ZS.test(e)};function TG(e,t){e===""&&(e="."),e=e.replace(/\/$/,"");for(var r=0;t.indexOf(e+"/")!==0;){var n=e.lastIndexOf("/");if(n<0||(e=e.slice(0,n),e.match(/^([^\/]+:\/)?\/*$/)))return t;++r}return Array(r+1).join("../")+t.substr(e.length+1)}dt.relative=TG;var t1=(function(){var e=Object.create(null);return!("__proto__"in e)})();function r1(e){return e}function MG(e){return n1(e)?"$"+e:e}dt.toSetString=t1?r1:MG;function RG(e){return n1(e)?e.slice(1):e}dt.fromSetString=t1?r1:RG;function n1(e){if(!e)return!1;var t=e.length;if(t<9||e.charCodeAt(t-1)!==95||e.charCodeAt(t-2)!==95||e.charCodeAt(t-3)!==111||e.charCodeAt(t-4)!==116||e.charCodeAt(t-5)!==111||e.charCodeAt(t-6)!==114||e.charCodeAt(t-7)!==112||e.charCodeAt(t-8)!==95||e.charCodeAt(t-9)!==95)return!1;for(var r=t-10;r>=0;r--)if(e.charCodeAt(r)!==36)return!1;return!0}function QG(e,t,r){var n=Yn(e.source,t.source);return n!==0||(n=e.originalLine-t.originalLine,n!==0)||(n=e.originalColumn-t.originalColumn,n!==0||r)||(n=e.generatedColumn-t.generatedColumn,n!==0)||(n=e.generatedLine-t.generatedLine,n!==0)?n:Yn(e.name,t.name)}dt.compareByOriginalPositions=QG;function _G(e,t,r){var n;return n=e.originalLine-t.originalLine,n!==0||(n=e.originalColumn-t.originalColumn,n!==0||r)||(n=e.generatedColumn-t.generatedColumn,n!==0)||(n=e.generatedLine-t.generatedLine,n!==0)?n:Yn(e.name,t.name)}dt.compareByOriginalPositionsNoSource=_G;function kG(e,t,r){var n=e.generatedLine-t.generatedLine;return n!==0||(n=e.generatedColumn-t.generatedColumn,n!==0||r)||(n=Yn(e.source,t.source),n!==0)||(n=e.originalLine-t.originalLine,n!==0)||(n=e.originalColumn-t.originalColumn,n!==0)?n:Yn(e.name,t.name)}dt.compareByGeneratedPositionsDeflated=kG;function DG(e,t,r){var n=e.generatedColumn-t.generatedColumn;return n!==0||r||(n=Yn(e.source,t.source),n!==0)||(n=e.originalLine-t.originalLine,n!==0)||(n=e.originalColumn-t.originalColumn,n!==0)?n:Yn(e.name,t.name)}dt.compareByGeneratedPositionsDeflatedNoLine=DG;function Yn(e,t){return e===t?0:e===null?1:t===null?-1:e>t?1:-1}function NG(e,t){var r=e.generatedLine-t.generatedLine;return r!==0||(r=e.generatedColumn-t.generatedColumn,r!==0)||(r=Yn(e.source,t.source),r!==0)||(r=e.originalLine-t.originalLine,r!==0)||(r=e.originalColumn-t.originalColumn,r!==0)?r:Yn(e.name,t.name)}dt.compareByGeneratedPositionsInflated=NG;function LG(e){return JSON.parse(e.replace(/^\)]}'[^\n]*\n/,""))}dt.parseSourceMapInput=LG;function PG(e,t,r){if(t=t||"",e&&(e[e.length-1]!=="/"&&t[0]!=="/"&&(e+="/"),t=e+t),r){var n=Fc(r);if(!n)throw new Error("sourceMapURL could not be parsed");if(n.path){var o=n.path.lastIndexOf("/");o>=0&&(n.path=n.path.substring(0,o+1))}t=e1(Ys(n),t)}return Tg(t)}dt.computeSourceURL=PG});var Qg=K(o1=>{var Mg=qs(),Rg=Object.prototype.hasOwnProperty,yi=typeof Map<"u";function qn(){this._array=[],this._set=yi?new Map:Object.create(null)}qn.fromArray=function(t,r){for(var n=new qn,o=0,i=t.length;o<i;o++)n.add(t[o],r);return n};qn.prototype.size=function(){return yi?this._set.size:Object.getOwnPropertyNames(this._set).length};qn.prototype.add=function(t,r){var n=yi?t:Mg.toSetString(t),o=yi?this.has(t):Rg.call(this._set,n),i=this._array.length;(!o||r)&&this._array.push(t),o||(yi?this._set.set(t,i):this._set[n]=i)};qn.prototype.has=function(t){if(yi)return this._set.has(t);var r=Mg.toSetString(t);return Rg.call(this._set,r)};qn.prototype.indexOf=function(t){if(yi){var r=this._set.get(t);if(r>=0)return r}else{var n=Mg.toSetString(t);if(Rg.call(this._set,n))return this._set[n]}throw new Error('"'+t+'" is not in the set.')};qn.prototype.at=function(t){if(t>=0&&t<this._array.length)return this._array[t];throw new Error("No element indexed by "+t)};qn.prototype.toArray=function(){return this._array.slice()};o1.ArraySet=qn});var a1=K(s1=>{var i1=qs();function FG(e,t){var r=e.generatedLine,n=t.generatedLine,o=e.generatedColumn,i=t.generatedColumn;return n>r||n==r&&i>=o||i1.compareByGeneratedPositionsInflated(e,t)<=0}function Ef(){this._array=[],this._sorted=!0,this._last={generatedLine:-1,generatedColumn:0}}Ef.prototype.unsortedForEach=function(t,r){this._array.forEach(t,r)};Ef.prototype.add=function(t){FG(this._last,t)?(this._last=t,this._array.push(t)):(this._sorted=!1,this._array.push(t))};Ef.prototype.toArray=function(){return this._sorted||(this._array.sort(i1.compareByGeneratedPositionsInflated),this._sorted=!0),this._array};s1.MappingList=Ef});var _g=K(c1=>{var Oc=Bg(),ze=qs(),wf=Qg().ArraySet,OG=a1().MappingList;function Tr(e){e||(e={}),this._file=ze.getArg(e,"file",null),this._sourceRoot=ze.getArg(e,"sourceRoot",null),this._skipValidation=ze.getArg(e,"skipValidation",!1),this._ignoreInvalidMapping=ze.getArg(e,"ignoreInvalidMapping",!1),this._sources=new wf,this._names=new wf,this._mappings=new OG,this._sourcesContents=null}Tr.prototype._version=3;Tr.fromSourceMap=function(t,r){var n=t.sourceRoot,o=new Tr(Object.assign(r||{},{file:t.file,sourceRoot:n}));return t.eachMapping(function(i){var s={generated:{line:i.generatedLine,column:i.generatedColumn}};i.source!=null&&(s.source=i.source,n!=null&&(s.source=ze.relative(n,s.source)),s.original={line:i.originalLine,column:i.originalColumn},i.name!=null&&(s.name=i.name)),o.addMapping(s)}),t.sources.forEach(function(i){var s=i;n!==null&&(s=ze.relative(n,i)),o._sources.has(s)||o._sources.add(s);var a=t.sourceContentFor(i);a!=null&&o.setSourceContent(i,a)}),o};Tr.prototype.addMapping=function(t){var r=ze.getArg(t,"generated"),n=ze.getArg(t,"original",null),o=ze.getArg(t,"source",null),i=ze.getArg(t,"name",null);!this._skipValidation&&this._validateMapping(r,n,o,i)===!1||(o!=null&&(o=String(o),this._sources.has(o)||this._sources.add(o)),i!=null&&(i=String(i),this._names.has(i)||this._names.add(i)),this._mappings.add({generatedLine:r.line,generatedColumn:r.column,originalLine:n!=null&&n.line,originalColumn:n!=null&&n.column,source:o,name:i}))};Tr.prototype.setSourceContent=function(t,r){var n=t;this._sourceRoot!=null&&(n=ze.relative(this._sourceRoot,n)),r!=null?(this._sourcesContents||(this._sourcesContents=Object.create(null)),this._sourcesContents[ze.toSetString(n)]=r):this._sourcesContents&&(delete this._sourcesContents[ze.toSetString(n)],Object.keys(this._sourcesContents).length===0&&(this._sourcesContents=null))};Tr.prototype.applySourceMap=function(t,r,n){var o=r;if(r==null){if(t.file==null)throw new Error(`SourceMapGenerator.prototype.applySourceMap requires either an explicit source file, or the source map's "file" property. Both were omitted.`);o=t.file}var i=this._sourceRoot;i!=null&&(o=ze.relative(i,o));var s=new wf,a=new wf;this._mappings.unsortedForEach(function(c){if(c.source===o&&c.originalLine!=null){var l=t.originalPositionFor({line:c.originalLine,column:c.originalColumn});l.source!=null&&(c.source=l.source,n!=null&&(c.source=ze.join(n,c.source)),i!=null&&(c.source=ze.relative(i,c.source)),c.originalLine=l.line,c.originalColumn=l.column,l.name!=null&&(c.name=l.name))}var u=c.source;u!=null&&!s.has(u)&&s.add(u);var d=c.name;d!=null&&!a.has(d)&&a.add(d)},this),this._sources=s,this._names=a,t.sources.forEach(function(c){var l=t.sourceContentFor(c);l!=null&&(n!=null&&(c=ze.join(n,c)),i!=null&&(c=ze.relative(i,c)),this.setSourceContent(c,l))},this)};Tr.prototype._validateMapping=function(t,r,n,o){if(r&&typeof r.line!="number"&&typeof r.column!="number"){var i="original.line and original.column are not numbers -- you probably meant to omit the original mapping entirely and only map the generated position. If so, pass null for the original mapping instead of an object with empty or null values.";if(this._ignoreInvalidMapping)return typeof console<"u"&&console.warn&&console.warn(i),!1;throw new Error(i)}if(!(t&&"line"in t&&"column"in t&&t.line>0&&t.column>=0&&!r&&!n&&!o)){if(t&&"line"in t&&"column"in t&&r&&"line"in r&&"column"in r&&t.line>0&&t.column>=0&&r.line>0&&r.column>=0&&n)return;var i="Invalid mapping: "+JSON.stringify({generated:t,source:n,original:r,name:o});if(this._ignoreInvalidMapping)return typeof console<"u"&&console.warn&&console.warn(i),!1;throw new Error(i)}};Tr.prototype._serializeMappings=function(){for(var t=0,r=1,n=0,o=0,i=0,s=0,a="",c,l,u,d,A=this._mappings.toArray(),f=0,g=A.length;f<g;f++){if(l=A[f],c="",l.generatedLine!==r)for(t=0;l.generatedLine!==r;)c+=";",r++;else if(f>0){if(!ze.compareByGeneratedPositionsInflated(l,A[f-1]))continue;c+=","}c+=Oc.encode(l.generatedColumn-t),t=l.generatedColumn,l.source!=null&&(d=this._sources.indexOf(l.source),c+=Oc.encode(d-s),s=d,c+=Oc.encode(l.originalLine-1-o),o=l.originalLine-1,c+=Oc.encode(l.originalColumn-n),n=l.originalColumn,l.name!=null&&(u=this._names.indexOf(l.name),c+=Oc.encode(u-i),i=u)),a+=c}return a};Tr.prototype._generateSourcesContent=function(t,r){return t.map(function(n){if(!this._sourcesContents)return null;r!=null&&(n=ze.relative(r,n));var o=ze.toSetString(n);return Object.prototype.hasOwnProperty.call(this._sourcesContents,o)?this._sourcesContents[o]:null},this)};Tr.prototype.toJSON=function(){var t={version:this._version,sources:this._sources.toArray(),names:this._names.toArray(),mappings:this._serializeMappings()};return this._file!=null&&(t.file=this._file),this._sourceRoot!=null&&(t.sourceRoot=this._sourceRoot),this._sourcesContents&&(t.sourcesContent=this._generateSourcesContent(t.sources,t.sourceRoot)),t};Tr.prototype.toString=function(){return JSON.stringify(this.toJSON())};c1.SourceMapGenerator=Tr});var l1=K(xi=>{xi.GREATEST_LOWER_BOUND=1;xi.LEAST_UPPER_BOUND=2;function kg(e,t,r,n,o,i){var s=Math.floor((t-e)/2)+e,a=o(r,n[s],!0);return a===0?s:a>0?t-s>1?kg(s,t,r,n,o,i):i==xi.LEAST_UPPER_BOUND?t<n.length?t:-1:s:s-e>1?kg(e,s,r,n,o,i):i==xi.LEAST_UPPER_BOUND?s:e<0?-1:e}xi.search=function(t,r,n,o){if(r.length===0)return-1;var i=kg(-1,r.length,t,r,n,o||xi.GREATEST_LOWER_BOUND);if(i<0)return-1;for(;i-1>=0&&n(r[i],r[i-1],!0)===0;)--i;return i}});var d1=K(f1=>{function GG(e){function t(o,i,s){var a=o[i];o[i]=o[s],o[s]=a}function r(o,i){return Math.round(o+Math.random()*(i-o))}function n(o,i,s,a){if(s<a){var c=r(s,a),l=s-1;t(o,c,a);for(var u=o[a],d=s;d<a;d++)i(o[d],u,!1)<=0&&(l+=1,t(o,l,d));t(o,l+1,d);var A=l+1;n(o,i,s,A-1),n(o,i,A+1,a)}}return n}function UG(e){let t=GG.toString();return new Function(`return ${t}`)()(e)}var u1=new WeakMap;f1.quickSort=function(e,t,r=0){let n=u1.get(t);n===void 0&&(n=UG(t),u1.set(t,n)),n(e,t,r,e.length-1)}});var p1=K(If=>{var H=qs(),Ng=l1(),zs=Qg().ArraySet,HG=Bg(),Gc=d1().quickSort;function Re(e,t){var r=e;return typeof e=="string"&&(r=H.parseSourceMapInput(e)),r.sections!=null?new qr(r,t):new xt(r,t)}Re.fromSourceMap=function(e,t){return xt.fromSourceMap(e,t)};Re.prototype._version=3;Re.prototype.__generatedMappings=null;Object.defineProperty(Re.prototype,"_generatedMappings",{configurable:!0,enumerable:!0,get:function(){return this.__generatedMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__generatedMappings}});Re.prototype.__originalMappings=null;Object.defineProperty(Re.prototype,"_originalMappings",{configurable:!0,enumerable:!0,get:function(){return this.__originalMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__originalMappings}});Re.prototype._charIsMappingSeparator=function(t,r){var n=t.charAt(r);return n===";"||n===","};Re.prototype._parseMappings=function(t,r){throw new Error("Subclasses must implement _parseMappings")};Re.GENERATED_ORDER=1;Re.ORIGINAL_ORDER=2;Re.GREATEST_LOWER_BOUND=1;Re.LEAST_UPPER_BOUND=2;Re.prototype.eachMapping=function(t,r,n){var o=r||null,i=n||Re.GENERATED_ORDER,s;switch(i){case Re.GENERATED_ORDER:s=this._generatedMappings;break;case Re.ORIGINAL_ORDER:s=this._originalMappings;break;default:throw new Error("Unknown order of iteration.")}for(var a=this.sourceRoot,c=t.bind(o),l=this._names,u=this._sources,d=this._sourceMapURL,A=0,f=s.length;A<f;A++){var g=s[A],h=g.source===null?null:u.at(g.source);h!==null&&(h=H.computeSourceURL(a,h,d)),c({source:h,generatedLine:g.generatedLine,generatedColumn:g.generatedColumn,originalLine:g.originalLine,originalColumn:g.originalColumn,name:g.name===null?null:l.at(g.name)})}};Re.prototype.allGeneratedPositionsFor=function(t){var r=H.getArg(t,"line"),n={source:H.getArg(t,"source"),originalLine:r,originalColumn:H.getArg(t,"column",0)};if(n.source=this._findSourceIndex(n.source),n.source<0)return[];var o=[],i=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",H.compareByOriginalPositions,Ng.LEAST_UPPER_BOUND);if(i>=0){var s=this._originalMappings[i];if(t.column===void 0)for(var a=s.originalLine;s&&s.originalLine===a;)o.push({line:H.getArg(s,"generatedLine",null),column:H.getArg(s,"generatedColumn",null),lastColumn:H.getArg(s,"lastGeneratedColumn",null)}),s=this._originalMappings[++i];else for(var c=s.originalColumn;s&&s.originalLine===r&&s.originalColumn==c;)o.push({line:H.getArg(s,"generatedLine",null),column:H.getArg(s,"generatedColumn",null),lastColumn:H.getArg(s,"lastGeneratedColumn",null)}),s=this._originalMappings[++i]}return o};If.SourceMapConsumer=Re;function xt(e,t){var r=e;typeof e=="string"&&(r=H.parseSourceMapInput(e));var n=H.getArg(r,"version"),o=H.getArg(r,"sources"),i=H.getArg(r,"names",[]),s=H.getArg(r,"sourceRoot",null),a=H.getArg(r,"sourcesContent",null),c=H.getArg(r,"mappings"),l=H.getArg(r,"file",null);if(n!=this._version)throw new Error("Unsupported version: "+n);s&&(s=H.normalize(s)),o=o.map(String).map(H.normalize).map(function(u){return s&&H.isAbsolute(s)&&H.isAbsolute(u)?H.relative(s,u):u}),this._names=zs.fromArray(i.map(String),!0),this._sources=zs.fromArray(o,!0),this._absoluteSources=this._sources.toArray().map(function(u){return H.computeSourceURL(s,u,t)}),this.sourceRoot=s,this.sourcesContent=a,this._mappings=c,this._sourceMapURL=t,this.file=l}xt.prototype=Object.create(Re.prototype);xt.prototype.consumer=Re;xt.prototype._findSourceIndex=function(e){var t=e;if(this.sourceRoot!=null&&(t=H.relative(this.sourceRoot,t)),this._sources.has(t))return this._sources.indexOf(t);var r;for(r=0;r<this._absoluteSources.length;++r)if(this._absoluteSources[r]==e)return r;return-1};xt.fromSourceMap=function(t,r){var n=Object.create(xt.prototype),o=n._names=zs.fromArray(t._names.toArray(),!0),i=n._sources=zs.fromArray(t._sources.toArray(),!0);n.sourceRoot=t._sourceRoot,n.sourcesContent=t._generateSourcesContent(n._sources.toArray(),n.sourceRoot),n.file=t._file,n._sourceMapURL=r,n._absoluteSources=n._sources.toArray().map(function(f){return H.computeSourceURL(n.sourceRoot,f,r)});for(var s=t._mappings.toArray().slice(),a=n.__generatedMappings=[],c=n.__originalMappings=[],l=0,u=s.length;l<u;l++){var d=s[l],A=new m1;A.generatedLine=d.generatedLine,A.generatedColumn=d.generatedColumn,d.source&&(A.source=i.indexOf(d.source),A.originalLine=d.originalLine,A.originalColumn=d.originalColumn,d.name&&(A.name=o.indexOf(d.name)),c.push(A)),a.push(A)}return Gc(n.__originalMappings,H.compareByOriginalPositions),n};xt.prototype._version=3;Object.defineProperty(xt.prototype,"sources",{get:function(){return this._absoluteSources.slice()}});function m1(){this.generatedLine=0,this.generatedColumn=0,this.source=null,this.originalLine=null,this.originalColumn=null,this.name=null}var Dg=H.compareByGeneratedPositionsDeflatedNoLine;function A1(e,t){let r=e.length,n=e.length-t;if(!(n<=1))if(n==2){let o=e[t],i=e[t+1];Dg(o,i)>0&&(e[t]=i,e[t+1]=o)}else if(n<20)for(let o=t;o<r;o++)for(let i=o;i>t;i--){let s=e[i-1],a=e[i];if(Dg(s,a)<=0)break;e[i-1]=a,e[i]=s}else Gc(e,Dg,t)}xt.prototype._parseMappings=function(t,r){var n=1,o=0,i=0,s=0,a=0,c=0,l=t.length,u=0,d={},A={},f=[],g=[],h,y,E,x,S;let w=0;for(;u<l;)if(t.charAt(u)===";")n++,u++,o=0,A1(g,w),w=g.length;else if(t.charAt(u)===",")u++;else{for(h=new m1,h.generatedLine=n,x=u;x<l&&!this._charIsMappingSeparator(t,x);x++);for(y=t.slice(u,x),E=[];u<x;)HG.decode(t,u,A),S=A.value,u=A.rest,E.push(S);if(E.length===2)throw new Error("Found a source, but no line and column");if(E.length===3)throw new Error("Found a source and line, but no column");if(h.generatedColumn=o+E[0],o=h.generatedColumn,E.length>1&&(h.source=a+E[1],a+=E[1],h.originalLine=i+E[2],i=h.originalLine,h.originalLine+=1,h.originalColumn=s+E[3],s=h.originalColumn,E.length>4&&(h.name=c+E[4],c+=E[4])),g.push(h),typeof h.originalLine=="number"){let v=h.source;for(;f.length<=v;)f.push(null);f[v]===null&&(f[v]=[]),f[v].push(h)}}A1(g,w),this.__generatedMappings=g;for(var I=0;I<f.length;I++)f[I]!=null&&Gc(f[I],H.compareByOriginalPositionsNoSource);this.__originalMappings=[].concat(...f)};xt.prototype._findMapping=function(t,r,n,o,i,s){if(t[n]<=0)throw new TypeError("Line must be greater than or equal to 1, got "+t[n]);if(t[o]<0)throw new TypeError("Column must be greater than or equal to 0, got "+t[o]);return Ng.search(t,r,i,s)};xt.prototype.computeColumnSpans=function(){for(var t=0;t<this._generatedMappings.length;++t){var r=this._generatedMappings[t];if(t+1<this._generatedMappings.length){var n=this._generatedMappings[t+1];if(r.generatedLine===n.generatedLine){r.lastGeneratedColumn=n.generatedColumn-1;continue}}r.lastGeneratedColumn=1/0}};xt.prototype.originalPositionFor=function(t){var r={generatedLine:H.getArg(t,"line"),generatedColumn:H.getArg(t,"column")},n=this._findMapping(r,this._generatedMappings,"generatedLine","generatedColumn",H.compareByGeneratedPositionsDeflated,H.getArg(t,"bias",Re.GREATEST_LOWER_BOUND));if(n>=0){var o=this._generatedMappings[n];if(o.generatedLine===r.generatedLine){var i=H.getArg(o,"source",null);i!==null&&(i=this._sources.at(i),i=H.computeSourceURL(this.sourceRoot,i,this._sourceMapURL));var s=H.getArg(o,"name",null);return s!==null&&(s=this._names.at(s)),{source:i,line:H.getArg(o,"originalLine",null),column:H.getArg(o,"originalColumn",null),name:s}}}return{source:null,line:null,column:null,name:null}};xt.prototype.hasContentsOfAllSources=function(){return this.sourcesContent?this.sourcesContent.length>=this._sources.size()&&!this.sourcesContent.some(function(t){return t==null}):!1};xt.prototype.sourceContentFor=function(t,r){if(!this.sourcesContent)return null;var n=this._findSourceIndex(t);if(n>=0)return this.sourcesContent[n];var o=t;this.sourceRoot!=null&&(o=H.relative(this.sourceRoot,o));var i;if(this.sourceRoot!=null&&(i=H.urlParse(this.sourceRoot))){var s=o.replace(/^file:\/\//,"");if(i.scheme=="file"&&this._sources.has(s))return this.sourcesContent[this._sources.indexOf(s)];if((!i.path||i.path=="/")&&this._sources.has("/"+o))return this.sourcesContent[this._sources.indexOf("/"+o)]}if(r)return null;throw new Error('"'+o+'" is not in the SourceMap.')};xt.prototype.generatedPositionFor=function(t){var r=H.getArg(t,"source");if(r=this._findSourceIndex(r),r<0)return{line:null,column:null,lastColumn:null};var n={source:r,originalLine:H.getArg(t,"line"),originalColumn:H.getArg(t,"column")},o=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",H.compareByOriginalPositions,H.getArg(t,"bias",Re.GREATEST_LOWER_BOUND));if(o>=0){var i=this._originalMappings[o];if(i.source===n.source)return{line:H.getArg(i,"generatedLine",null),column:H.getArg(i,"generatedColumn",null),lastColumn:H.getArg(i,"lastGeneratedColumn",null)}}return{line:null,column:null,lastColumn:null}};If.BasicSourceMapConsumer=xt;function qr(e,t){var r=e;typeof e=="string"&&(r=H.parseSourceMapInput(e));var n=H.getArg(r,"version"),o=H.getArg(r,"sections");if(n!=this._version)throw new Error("Unsupported version: "+n);this._sources=new zs,this._names=new zs;var i={line:-1,column:0};this._sections=o.map(function(s){if(s.url)throw new Error("Support for url field in sections not implemented.");var a=H.getArg(s,"offset"),c=H.getArg(a,"line"),l=H.getArg(a,"column");if(c<i.line||c===i.line&&l<i.column)throw new Error("Section offsets must be ordered and non-overlapping.");return i=a,{generatedOffset:{generatedLine:c+1,generatedColumn:l+1},consumer:new Re(H.getArg(s,"map"),t)}})}qr.prototype=Object.create(Re.prototype);qr.prototype.constructor=Re;qr.prototype._version=3;Object.defineProperty(qr.prototype,"sources",{get:function(){for(var e=[],t=0;t<this._sections.length;t++)for(var r=0;r<this._sections[t].consumer.sources.length;r++)e.push(this._sections[t].consumer.sources[r]);return e}});qr.prototype.originalPositionFor=function(t){var r={generatedLine:H.getArg(t,"line"),generatedColumn:H.getArg(t,"column")},n=Ng.search(r,this._sections,function(i,s){var a=i.generatedLine-s.generatedOffset.generatedLine;return a||i.generatedColumn-s.generatedOffset.generatedColumn}),o=this._sections[n];return o?o.consumer.originalPositionFor({line:r.generatedLine-(o.generatedOffset.generatedLine-1),column:r.generatedColumn-(o.generatedOffset.generatedLine===r.generatedLine?o.generatedOffset.generatedColumn-1:0),bias:t.bias}):{source:null,line:null,column:null,name:null}};qr.prototype.hasContentsOfAllSources=function(){return this._sections.every(function(t){return t.consumer.hasContentsOfAllSources()})};qr.prototype.sourceContentFor=function(t,r){for(var n=0;n<this._sections.length;n++){var o=this._sections[n],i=o.consumer.sourceContentFor(t,!0);if(i||i==="")return i}if(r)return null;throw new Error('"'+t+'" is not in the SourceMap.')};qr.prototype.generatedPositionFor=function(t){for(var r=0;r<this._sections.length;r++){var n=this._sections[r];if(n.consumer._findSourceIndex(H.getArg(t,"source"))!==-1){var o=n.consumer.generatedPositionFor(t);if(o){var i={line:o.line+(n.generatedOffset.generatedLine-1),column:o.column+(n.generatedOffset.generatedLine===o.line?n.generatedOffset.generatedColumn-1:0)};return i}}}return{line:null,column:null}};qr.prototype._parseMappings=function(t,r){this.__generatedMappings=[],this.__originalMappings=[];for(var n=0;n<this._sections.length;n++)for(var o=this._sections[n],i=o.consumer._generatedMappings,s=0;s<i.length;s++){var a=i[s],c=o.consumer._sources.at(a.source);c!==null&&(c=H.computeSourceURL(o.consumer.sourceRoot,c,this._sourceMapURL)),this._sources.add(c),c=this._sources.indexOf(c);var l=null;a.name&&(l=o.consumer._names.at(a.name),this._names.add(l),l=this._names.indexOf(l));var u={source:c,generatedLine:a.generatedLine+(o.generatedOffset.generatedLine-1),generatedColumn:a.generatedColumn+(o.generatedOffset.generatedLine===a.generatedLine?o.generatedOffset.generatedColumn-1:0),originalLine:a.originalLine,originalColumn:a.originalColumn,name:l};this.__generatedMappings.push(u),typeof u.originalLine=="number"&&this.__originalMappings.push(u)}Gc(this.__generatedMappings,H.compareByGeneratedPositionsDeflated),Gc(this.__originalMappings,H.compareByOriginalPositions)};If.IndexedSourceMapConsumer=qr});var h1=K(g1=>{var VG=_g().SourceMapGenerator,Sf=qs(),jG=/(\r?\n)/,$G=10,Js="$$$isSourceNode$$$";function ar(e,t,r,n,o){this.children=[],this.sourceContents={},this.line=e??null,this.column=t??null,this.source=r??null,this.name=o??null,this[Js]=!0,n!=null&&this.add(n)}ar.fromStringWithSourceMap=function(t,r,n){var o=new ar,i=t.split(jG),s=0,a=function(){var A=g(),f=g()||"";return A+f;function g(){return s<i.length?i[s++]:void 0}},c=1,l=0,u=null;return r.eachMapping(function(A){if(u!==null)if(c<A.generatedLine)d(u,a()),c++,l=0;else{var f=i[s]||"",g=f.substr(0,A.generatedColumn-l);i[s]=f.substr(A.generatedColumn-l),l=A.generatedColumn,d(u,g),u=A;return}for(;c<A.generatedLine;)o.add(a()),c++;if(l<A.generatedColumn){var f=i[s]||"";o.add(f.substr(0,A.generatedColumn)),i[s]=f.substr(A.generatedColumn),l=A.generatedColumn}u=A},this),s<i.length&&(u&&d(u,a()),o.add(i.splice(s).join(""))),r.sources.forEach(function(A){var f=r.sourceContentFor(A);f!=null&&(n!=null&&(A=Sf.join(n,A)),o.setSourceContent(A,f))}),o;function d(A,f){if(A===null||A.source===void 0)o.add(f);else{var g=n?Sf.join(n,A.source):A.source;o.add(new ar(A.originalLine,A.originalColumn,g,f,A.name))}}};ar.prototype.add=function(t){if(Array.isArray(t))t.forEach(function(r){this.add(r)},this);else if(t[Js]||typeof t=="string")t&&this.children.push(t);else throw new TypeError("Expected a SourceNode, string, or an array of SourceNodes and strings. Got "+t);return this};ar.prototype.prepend=function(t){if(Array.isArray(t))for(var r=t.length-1;r>=0;r--)this.prepend(t[r]);else if(t[Js]||typeof t=="string")this.children.unshift(t);else throw new TypeError("Expected a SourceNode, string, or an array of SourceNodes and strings. Got "+t);return this};ar.prototype.walk=function(t){for(var r,n=0,o=this.children.length;n<o;n++)r=this.children[n],r[Js]?r.walk(t):r!==""&&t(r,{source:this.source,line:this.line,column:this.column,name:this.name})};ar.prototype.join=function(t){var r,n,o=this.children.length;if(o>0){for(r=[],n=0;n<o-1;n++)r.push(this.children[n]),r.push(t);r.push(this.children[n]),this.children=r}return this};ar.prototype.replaceRight=function(t,r){var n=this.children[this.children.length-1];return n[Js]?n.replaceRight(t,r):typeof n=="string"?this.children[this.children.length-1]=n.replace(t,r):this.children.push("".replace(t,r)),this};ar.prototype.setSourceContent=function(t,r){this.sourceContents[Sf.toSetString(t)]=r};ar.prototype.walkSourceContents=function(t){for(var r=0,n=this.children.length;r<n;r++)this.children[r][Js]&&this.children[r].walkSourceContents(t);for(var o=Object.keys(this.sourceContents),r=0,n=o.length;r<n;r++)t(Sf.fromSetString(o[r]),this.sourceContents[o[r]])};ar.prototype.toString=function(){var t="";return this.walk(function(r){t+=r}),t};ar.prototype.toStringWithSourceMap=function(t){var r={code:"",line:1,column:0},n=new VG(t),o=!1,i=null,s=null,a=null,c=null;return this.walk(function(l,u){r.code+=l,u.source!==null&&u.line!==null&&u.column!==null?((i!==u.source||s!==u.line||a!==u.column||c!==u.name)&&n.addMapping({source:u.source,original:{line:u.line,column:u.column},generated:{line:r.line,column:r.column},name:u.name}),i=u.source,s=u.line,a=u.column,c=u.name,o=!0):o&&(n.addMapping({generated:{line:r.line,column:r.column}}),i=null,o=!1);for(var d=0,A=l.length;d<A;d++)l.charCodeAt(d)===$G?(r.line++,r.column=0,d+1===A?(i=null,o=!1):o&&n.addMapping({source:u.source,original:{line:u.line,column:u.column},generated:{line:r.line,column:r.column},name:u.name})):r.column++}),this.walkSourceContents(function(l,u){n.setSourceContent(l,u)}),{code:r.code,map:n}};g1.SourceNode=ar});var y1=K(vf=>{vf.SourceMapGenerator=_g().SourceMapGenerator;vf.SourceMapConsumer=p1().SourceMapConsumer;vf.SourceNode=h1().SourceNode});var x1,C1,b1=m(()=>{"use client";sr();x1=p(O(),1),C1=(0,Me.createSvgIcon)((0,x1.jsx)("path",{d:"M19 19H5V5h7V3H5c-1.11 0-2 .9-2 2v14c0 1.1.89 2 2 2h14c1.1 0 2-.9 2-2v-7h-2zM14 3v2h3.59l-9.83 9.83 1.41 1.41L19 6.41V10h2V3z"}),"OpenInNew")});function Tf(e){let{children:t,...r}=e;return(0,Bf.jsxs)(E1.Link,{...r,target:"_blank",rel:"noopener noreferrer",children:[t," ",(0,Bf.jsx)(C1,{fontSize:"small"})]})}var Bf,E1,w1=m(()=>{Bf=p(O(),1);b1();E1=p(U(),1)});function Lg({text:e,extra:t}){let{classes:r}=WG(),n=t?`supporting data: ${JSON.stringify(t,null,2)}`:"",o=[e,n].filter(Boolean).join(`
+export default theme;`}var Rp=m(()=>{Fn()});function fw(e){return typeof e=="number"?`${(e*100).toFixed(0)}%`:`calc((${e}) * 100%)`}function v4(e){Object.assign(e,{alpha(t,r){let n=this||e;return n.colorSpace?`oklch(from ${t} l c h / ${typeof r=="string"?`calc(${r})`:r})`:n.vars?`rgba(${t.replace(/var\(--([^,\s)]+)(?:,[^)]+)?\)+/g,"var(--$1Channel)")} / ${typeof r=="string"?`calc(${r})`:r})`:gp(t,S4(r))},lighten(t,r){let n=this||e;return n.colorSpace?`color-mix(in ${n.colorSpace}, ${t}, #fff ${fw(r)})`:Ds(t,r)},darken(t,r){let n=this||e;return n.colorSpace?`color-mix(in ${n.colorSpace}, ${t}, #000 ${fw(r)})`:ks(t,r)}})}function B4(e={},...t){let{breakpoints:r,mixins:n={},spacing:o,palette:i={},motion:s={},transitions:a={},typography:c={},shape:l,colorSpace:u,...d}=e;if(e.vars&&e.generateThemeVars===void 0)throw new Error(Jt(22));let A=ai({...i,colorSpace:u}),f=ni(e),g=Je(f,{mixins:vp(f.breakpoints,n),palette:A,shadows:ow.slice(),typography:Bp(A,c),motion:Mp(s),transitions:Tp(a),zIndex:{...lw}});return g=Je(g,d),g=t.reduce((h,x)=>Je(h,x),g),delete g.transitions.reducedMotion,g.unstable_sxConfig={...Pn,...d?.unstable_sxConfig},g.unstable_sx=function(x){return hr({sx:x,theme:this})},g.toRuntimeSource=rf,v4(g),g}var S4,Sc,Qp=m(()=>{cs();Fn();oc();Wu();Ec();ew();Ic();nw();iw();aw();cw();uw();Rp();S4=e=>{if(!Number.isNaN(+e))return+e;let t=e.match(/\d*\.?\d+/g);if(!t)return 0;let r=0;for(let n=0;n<t.length;n+=1)r+=+t[n];return r};Sc=B4});function _p(e){let t;return e<1?t=5.11916*e**2:t=4.5*Math.log(e+1)+2,Math.round(t*10)/1e3}var dw=m(()=>{});function kp(e){return{inputPlaceholder:e==="dark"?.5:.42,inputUnderline:e==="dark"?.7:.42,switchTrackDisabled:e==="dark"?.2:.12,switchTrack:e==="dark"?.3:.38}}function Dp(e){return e==="dark"?T4:[]}function Np(e){let{palette:t={mode:"light"},opacity:r,overlays:n,colorSpace:o,...i}=e,s=ai({...t,colorSpace:o});return{palette:s,opacity:{...kp(s.mode),...r},overlays:n||Dp(s.mode),...i}}var T4,Aw=m(()=>{Ic();dw();T4=[...Array(25)].map((e,t)=>{if(t===0)return"none";let r=_p(t);return`linear-gradient(rgba(255 255 255 / ${r}), rgba(255 255 255 / ${r}))`})});function Lp(e){return e[0]==="motion"||!!e[0].match(/(cssVarPrefix|colorSchemeSelector|modularCssLayers|rootSelector|typography|mixins|breakpoints|direction|transitions)/)||!!e[0].match(/sxConfig$/)||e[0]==="palette"&&!!e[1]?.match(/(mode|contrastThreshold|tonalOffset)/)}var mw=m(()=>{});var M4,pw,gw=m(()=>{M4=e=>[...[...Array(25)].map((t,r)=>`--${e?`${e}-`:""}overlays-${r}`),`--${e?`${e}-`:""}palette-AppBar-darkBg`,`--${e?`${e}-`:""}palette-AppBar-darkColor`],pw=M4});var hw,yw=m(()=>{gw();hw=e=>(t,r)=>{let n=e.rootSelector||":root",o=e.colorSchemeSelector,i=o;if(o==="class"&&(i=".%s"),o==="data"&&(i="[data-%s]"),o?.startsWith("data-")&&!o.includes("%s")&&(i=`[${o}="%s"]`),e.defaultColorScheme===t){if(t==="dark"){let s={};return pw(e.cssVarPrefix).forEach(a=>{s[a]=r[a],delete r[a]}),i==="media"?{[n]:r,"@media (prefers-color-scheme: dark)":{[n]:s}}:i?{[i.replace("%s",t)]:s,[`${n}, ${i.replace("%s",t)}`]:r}:{[n]:{...r,...s}}}if(i&&i!=="media")return`${n}, ${i.replace("%s",String(t))}`}else if(t){if(i==="media")return{[`@media (prefers-color-scheme: ${String(t)})`]:{[n]:r}};if(i)return i.replace("%s",String(t))}return n}});function R4(e,t){t.forEach(r=>{e[r]||(e[r]={})})}function _(e,t,r){!e[t]&&r&&(e[t]=r)}function vc(e){return typeof e!="string"||!e.startsWith("hsl")?e:pp(e)}function Un(e,t){`${t}Channel`in e||(e[`${t}Channel`]=_s(vc(e[t]),`MUI: Can't create \`palette.${t}Channel\` because \`palette.${t}\` is not one of these formats: #nnn, #nnnnnn, rgb(), rgba(), hsl(), hsla(), color().
+To suppress this warning, you need to explicitly provide the \`palette.${t}Channel\` as a string (in rgb format, for example "12 12 12") or undefined if you want to remove the channel token.`))}function Q4(e){return typeof e=="number"?`${e}px`:typeof e=="string"||typeof e=="function"||Array.isArray(e)?e:"8px"}function Fp(e,t,r,n,o){if(!r)return;r=r===!0?{}:r;let i=o==="dark"?"dark":"light";if(!n){t[o]=Np({...r,palette:{mode:i,...r?.palette},colorSpace:e});return}let{palette:s,...a}=Sc({...n,palette:{mode:i,...r?.palette},colorSpace:e});return t[o]={...r,palette:s,opacity:{...kp(i),...r?.opacity},overlays:r?.overlays||Dp(i)},a}function Pp(e={},...t){let{colorSchemes:r={light:!0},defaultColorScheme:n,disableCssColorScheme:o=!1,cssVarPrefix:i="mui",nativeColor:s=!1,shouldSkipGeneratingVar:a=Lp,colorSchemeSelector:c=r.light&&r.dark?"media":void 0,rootSelector:l=":root",...u}=e,d=Object.keys(r)[0],A=n||(r.light&&d!=="light"?"light":d),f=_4(i),{[A]:g,light:h,dark:x,...w}=r,y={...w},v=g;if((A==="dark"&&!("dark"in r)||A==="light"&&!("light"in r))&&(v=!0),!v)throw new Error(Jt(21,A));let b;s&&(b="oklch");let I=Fp(b,y,v,u,A);h&&!y.light&&Fp(b,y,h,void 0,"light"),x&&!y.dark&&Fp(b,y,x,void 0,"dark");let S={defaultColorScheme:A,...I,cssVarPrefix:i,colorSchemeSelector:c,rootSelector:l,getCssVar:f,colorSchemes:y,font:{...tf(I.typography),...I.font},spacing:Q4(u.spacing)};Object.keys(S.colorSchemes).forEach(P=>{let C=S.colorSchemes[P].palette,M=G=>{let j=G.split("-"),oe=j[1],te=j[2];return f(G,C[oe][te])};C.mode==="light"&&(_(C.common,"background","#fff"),_(C.common,"onBackground","#000")),C.mode==="dark"&&(_(C.common,"background","#000"),_(C.common,"onBackground","#fff"));function k(G,j,oe){if(b){let te;return G===go&&(te=`transparent ${((1-oe)*100).toFixed(0)}%`),G===ce&&(te=`#000 ${(oe*100).toFixed(0)}%`),G===le&&(te=`#fff ${(oe*100).toFixed(0)}%`),`color-mix(in ${b}, ${j}, ${te})`}return G(j,oe)}if(R4(C,["Alert","AppBar","Avatar","Button","Chip","FilledInput","LinearProgress","Skeleton","Slider","SnackbarContent","SpeedDialAction","StepConnector","StepContent","Switch","TableCell","Tooltip"]),C.mode==="light"){_(C.Alert,"errorColor",k(ce,s?f("palette-error-light"):C.error.light,.6)),_(C.Alert,"infoColor",k(ce,s?f("palette-info-light"):C.info.light,.6)),_(C.Alert,"successColor",k(ce,s?f("palette-success-light"):C.success.light,.6)),_(C.Alert,"warningColor",k(ce,s?f("palette-warning-light"):C.warning.light,.6)),_(C.Alert,"errorFilledBg",M("palette-error-main")),_(C.Alert,"infoFilledBg",M("palette-info-main")),_(C.Alert,"successFilledBg",M("palette-success-main")),_(C.Alert,"warningFilledBg",M("palette-warning-main")),_(C.Alert,"errorFilledColor",mn(()=>C.getContrastText(C.error.main))),_(C.Alert,"infoFilledColor",mn(()=>C.getContrastText(C.info.main))),_(C.Alert,"successFilledColor",mn(()=>C.getContrastText(C.success.main))),_(C.Alert,"warningFilledColor",mn(()=>C.getContrastText(C.warning.main))),_(C.Alert,"errorStandardBg",k(le,s?f("palette-error-light"):C.error.light,.9)),_(C.Alert,"infoStandardBg",k(le,s?f("palette-info-light"):C.info.light,.9)),_(C.Alert,"successStandardBg",k(le,s?f("palette-success-light"):C.success.light,.9)),_(C.Alert,"warningStandardBg",k(le,s?f("palette-warning-light"):C.warning.light,.9)),_(C.Alert,"errorIconColor",M("palette-error-main")),_(C.Alert,"infoIconColor",M("palette-info-main")),_(C.Alert,"successIconColor",M("palette-success-main")),_(C.Alert,"warningIconColor",M("palette-warning-main")),_(C.AppBar,"defaultBg",M("palette-grey-100")),_(C.Avatar,"defaultBg",M("palette-grey-400")),_(C.Button,"inheritContainedBg",M("palette-grey-300")),_(C.Button,"inheritContainedHoverBg",M("palette-grey-A100")),_(C.Chip,"defaultBorder",M("palette-grey-400")),_(C.Chip,"defaultAvatarColor",M("palette-grey-700")),_(C.Chip,"defaultIconColor",M("palette-grey-700")),_(C.FilledInput,"bg","rgba(0, 0, 0, 0.06)"),_(C.FilledInput,"hoverBg","rgba(0, 0, 0, 0.09)"),_(C.FilledInput,"disabledBg","rgba(0, 0, 0, 0.12)"),_(C.LinearProgress,"primaryBg",k(le,s?f("palette-primary-main"):C.primary.main,.62)),_(C.LinearProgress,"secondaryBg",k(le,s?f("palette-secondary-main"):C.secondary.main,.62)),_(C.LinearProgress,"errorBg",k(le,s?f("palette-error-main"):C.error.main,.62)),_(C.LinearProgress,"infoBg",k(le,s?f("palette-info-main"):C.info.main,.62)),_(C.LinearProgress,"successBg",k(le,s?f("palette-success-main"):C.success.main,.62)),_(C.LinearProgress,"warningBg",k(le,s?f("palette-warning-light"):C.warning.main,.62)),_(C.Skeleton,"bg",b?k(go,s?f("palette-text-primary"):C.text.primary,.11):`rgba(${M("palette-text-primaryChannel")} / 0.11)`),_(C.Slider,"primaryTrack",k(le,s?f("palette-primary-main"):C.primary.main,.62)),_(C.Slider,"secondaryTrack",k(le,s?f("palette-secondary-main"):C.secondary.main,.62)),_(C.Slider,"errorTrack",k(le,s?f("palette-error-main"):C.error.main,.62)),_(C.Slider,"infoTrack",k(le,s?f("palette-info-main"):C.info.main,.62)),_(C.Slider,"successTrack",k(le,s?f("palette-success-main"):C.success.main,.62)),_(C.Slider,"warningTrack",k(le,s?f("palette-warning-main"):C.warning.main,.62));let G=b?k(ce,s?f("palette-background-default"):C.background.default,.6825):Cc(C.background.default,.8);_(C.SnackbarContent,"bg",G),_(C.SnackbarContent,"color",mn(()=>b?ef.text.primary:C.getContrastText(G))),_(C.SpeedDialAction,"fabHoverBg",Cc(C.background.paper,.15)),_(C.StepConnector,"border",M("palette-grey-400")),_(C.StepContent,"border",M("palette-grey-400")),_(C.Switch,"defaultColor",M("palette-common-white")),_(C.Switch,"defaultDisabledColor",M("palette-grey-100")),_(C.Switch,"primaryDisabledColor",k(le,s?f("palette-primary-main"):C.primary.main,.62)),_(C.Switch,"secondaryDisabledColor",k(le,s?f("palette-secondary-main"):C.secondary.main,.62)),_(C.Switch,"errorDisabledColor",k(le,s?f("palette-error-main"):C.error.main,.62)),_(C.Switch,"infoDisabledColor",k(le,s?f("palette-info-main"):C.info.main,.62)),_(C.Switch,"successDisabledColor",k(le,s?f("palette-success-main"):C.success.main,.62)),_(C.Switch,"warningDisabledColor",k(le,s?f("palette-warning-main"):C.warning.main,.62)),_(C.TableCell,"border",k(le,go(s?f("palette-divider"):C.divider,1),.88)),_(C.Tooltip,"bg",k(go,s?f("palette-grey-700"):C.grey[700],.92))}if(C.mode==="dark"){_(C.Alert,"errorColor",k(le,s?f("palette-error-light"):C.error.light,.6)),_(C.Alert,"infoColor",k(le,s?f("palette-info-light"):C.info.light,.6)),_(C.Alert,"successColor",k(le,s?f("palette-success-light"):C.success.light,.6)),_(C.Alert,"warningColor",k(le,s?f("palette-warning-light"):C.warning.light,.6)),_(C.Alert,"errorFilledBg",M("palette-error-dark")),_(C.Alert,"infoFilledBg",M("palette-info-dark")),_(C.Alert,"successFilledBg",M("palette-success-dark")),_(C.Alert,"warningFilledBg",M("palette-warning-dark")),_(C.Alert,"errorFilledColor",mn(()=>C.getContrastText(C.error.dark))),_(C.Alert,"infoFilledColor",mn(()=>C.getContrastText(C.info.dark))),_(C.Alert,"successFilledColor",mn(()=>C.getContrastText(C.success.dark))),_(C.Alert,"warningFilledColor",mn(()=>C.getContrastText(C.warning.dark))),_(C.Alert,"errorStandardBg",k(ce,s?f("palette-error-light"):C.error.light,.9)),_(C.Alert,"infoStandardBg",k(ce,s?f("palette-info-light"):C.info.light,.9)),_(C.Alert,"successStandardBg",k(ce,s?f("palette-success-light"):C.success.light,.9)),_(C.Alert,"warningStandardBg",k(ce,s?f("palette-warning-light"):C.warning.light,.9)),_(C.Alert,"errorIconColor",M("palette-error-main")),_(C.Alert,"infoIconColor",M("palette-info-main")),_(C.Alert,"successIconColor",M("palette-success-main")),_(C.Alert,"warningIconColor",M("palette-warning-main")),_(C.AppBar,"defaultBg",M("palette-grey-900")),_(C.AppBar,"darkBg",M("palette-background-paper")),_(C.AppBar,"darkColor",M("palette-text-primary")),_(C.Avatar,"defaultBg",M("palette-grey-600")),_(C.Button,"inheritContainedBg",M("palette-grey-800")),_(C.Button,"inheritContainedHoverBg",M("palette-grey-700")),_(C.Chip,"defaultBorder",M("palette-grey-700")),_(C.Chip,"defaultAvatarColor",M("palette-grey-300")),_(C.Chip,"defaultIconColor",M("palette-grey-300")),_(C.FilledInput,"bg","rgba(255, 255, 255, 0.09)"),_(C.FilledInput,"hoverBg","rgba(255, 255, 255, 0.13)"),_(C.FilledInput,"disabledBg","rgba(255, 255, 255, 0.12)"),_(C.LinearProgress,"primaryBg",k(ce,s?f("palette-primary-main"):C.primary.main,.5)),_(C.LinearProgress,"secondaryBg",k(ce,s?f("palette-secondary-main"):C.secondary.main,.5)),_(C.LinearProgress,"errorBg",k(ce,s?f("palette-error-main"):C.error.main,.5)),_(C.LinearProgress,"infoBg",k(ce,s?f("palette-info-main"):C.info.main,.5)),_(C.LinearProgress,"successBg",k(ce,s?f("palette-success-main"):C.success.main,.5)),_(C.LinearProgress,"warningBg",k(ce,s?f("palette-warning-main"):C.warning.main,.5)),_(C.Skeleton,"bg",b?k(go,s?f("palette-text-primary"):C.text.primary,.13):`rgba(${M("palette-text-primaryChannel")} / 0.13)`),_(C.Slider,"primaryTrack",k(ce,s?f("palette-primary-main"):C.primary.main,.5)),_(C.Slider,"secondaryTrack",k(ce,s?f("palette-secondary-main"):C.secondary.main,.5)),_(C.Slider,"errorTrack",k(ce,s?f("palette-error-main"):C.error.main,.5)),_(C.Slider,"infoTrack",k(ce,s?f("palette-info-main"):C.info.main,.5)),_(C.Slider,"successTrack",k(ce,s?f("palette-success-main"):C.success.main,.5)),_(C.Slider,"warningTrack",k(ce,s?f("palette-warning-light"):C.warning.main,.5));let G=b?k(le,s?f("palette-background-default"):C.background.default,.985):Cc(C.background.default,.98);_(C.SnackbarContent,"bg",G),_(C.SnackbarContent,"color",mn(()=>b?Sp.text.primary:C.getContrastText(G))),_(C.SpeedDialAction,"fabHoverBg",Cc(C.background.paper,.15)),_(C.StepConnector,"border",M("palette-grey-600")),_(C.StepContent,"border",M("palette-grey-600")),_(C.Switch,"defaultColor",M("palette-grey-300")),_(C.Switch,"defaultDisabledColor",M("palette-grey-600")),_(C.Switch,"primaryDisabledColor",k(ce,s?f("palette-primary-main"):C.primary.main,.55)),_(C.Switch,"secondaryDisabledColor",k(ce,s?f("palette-secondary-main"):C.secondary.main,.55)),_(C.Switch,"errorDisabledColor",k(ce,s?f("palette-error-main"):C.error.main,.55)),_(C.Switch,"infoDisabledColor",k(ce,s?f("palette-info-main"):C.info.main,.55)),_(C.Switch,"successDisabledColor",k(ce,s?f("palette-success-main"):C.success.main,.55)),_(C.Switch,"warningDisabledColor",k(ce,s?f("palette-warning-light"):C.warning.main,.55)),_(C.TableCell,"border",k(ce,go(s?f("palette-divider"):C.divider,1),.68)),_(C.Tooltip,"bg",k(go,s?f("palette-grey-700"):C.grey[700],.92))}s||(Un(C.background,"default"),Un(C.background,"paper"),Un(C.common,"background"),Un(C.common,"onBackground"),Un(C,"divider")),Object.keys(C).forEach(G=>{let j=C[G];G!=="tonalOffset"&&!s&&j&&typeof j=="object"&&(j.main&&_(C[G],"mainChannel",_s(vc(j.main))),j.light&&_(C[G],"lightChannel",_s(vc(j.light))),j.dark&&_(C[G],"darkChannel",_s(vc(j.dark))),j.contrastText&&_(C[G],"contrastTextChannel",_s(vc(j.contrastText))),G==="text"&&(Un(C[G],"primary"),Un(C[G],"secondary")),G==="action"&&(j.active&&Un(C[G],"active"),j.selected&&Un(C[G],"selected")))})}),S=t.reduce((P,C)=>Je(P,C),S);let B={prefix:i,disableCssColorScheme:o,shouldSkipGeneratingVar:a,getSelector:hw(S),enableContrastVars:s},{vars:R,generateThemeVars:D,generateStyleSheets:L}=yp(S,B);return S.vars=R,Object.entries(S.colorSchemes[S.defaultColorScheme]).forEach(([P,C])=>{S[P]=C}),S.generateThemeVars=D,S.generateStyleSheets=L,S.generateSpacing=function(){return Ts(u.spacing,Za(this))},S.getColorSchemeSelector=xp(c),S.spacing=S.generateSpacing(),S.shouldSkipGeneratingVar=a,S.unstable_sxConfig={...Pn,...u?.unstable_sxConfig},S.unstable_sx=function(C){return hr({sx:C,theme:this})},S.internal_cache={},S.toRuntimeSource=rf,S}var mn,_4,xw=m(()=>{cs();Fn();Cp();Jo();Zb();oc();Ec();Qp();Aw();mw();yw();Rp();Ic();mn=e=>{try{return e()}catch{}},_4=(e="mui")=>Zu(e)});function Cw(e,t,r){e.colorSchemes&&r&&(e.colorSchemes[t]={...r!==!0&&r,palette:ai({...r===!0?{}:r.palette,mode:t})})}function Op(e={},...t){let{palette:r,cssVariables:n=!1,colorSchemes:o=r?void 0:{light:!0},defaultColorScheme:i=r?.mode,...s}=e,a=i||"light",c=o?.[a],l={...o,...r?{[a]:{...typeof c!="boolean"&&c,palette:r}}:void 0};if(n===!1){if(!("colorSchemes"in e))return Sc(e,...t);let u=r;"palette"in e||l[a]&&(l[a]!==!0?u=l[a].palette:a==="dark"&&(u={mode:"dark"}));let d=Sc({...e,palette:u},...t);return d.defaultColorScheme=a,d.colorSchemes=l,d.palette.mode==="light"&&(d.colorSchemes.light={...l.light!==!0&&l.light,palette:d.palette},Cw(d,"dark",l.dark)),d.palette.mode==="dark"&&(d.colorSchemes.dark={...l.dark!==!0&&l.dark,palette:d.palette},Cw(d,"light",l.light)),d}return!r&&!("light"in l)&&a==="light"&&(l.light=!0),Pp({...s,colorSchemes:l,defaultColorScheme:a,...typeof n!="boolean"&&n},...t)}var Ew=m(()=>{Ic();xw();Qp()});var k4,bw,ww=m(()=>{"use client";Ew();k4=Op(),bw=k4});var Iw,Sw=m(()=>{Iw="$$material"});function D4(e){return e!=="ownerState"&&e!=="theme"&&e!=="sx"&&e!=="as"}var vw,Bw=m(()=>{vw=D4});var N4,Tw,Mw=m(()=>{Bw();N4=e=>vw(e)&&e!=="classes",Tw=N4});var L4,Gp,Rw=m(()=>{"use client";fp();ww();Sw();Mw();L4=zu({themeId:Iw,defaultTheme:bw,rootShouldForwardProp:Tw}),Gp=L4});var F4,Qw=m(()=>{F4=p(O(),1);Rw()});var P4,_w,kw=m(()=>{Cp();P4=Xu,_w=P4});function Up(e){return hp(e)}var HZ,O4,Dw=m(()=>{"use client";HZ=p(Q(),1);vb();O4=p(O(),1)});var Nw=m(()=>{Dw()});function Lw(e){return Ms("MuiSvgIcon",e)}var JZ,Hp=m(()=>{Rs();sp();JZ=Cr("MuiSvgIcon",["root","colorPrimary","colorSecondary","colorAction","colorError","colorDisabled","fontSizeInherit","fontSizeSmall","fontSizeMedium","fontSizeLarge"])});function Pw(e,t){return e==="always"?t:e==="system"?{"@media (prefers-reduced-motion: reduce)":t}:null}var Fw,Ow=m(()=>{Fw={transition:"none"}});function V4(e,t){let r=t??Fw;return Pw(e.motion?.reducedMotion,r)}function Gw(e,t=U4,r=H4){let n=e.transitions?.create?.(t,r),o=V4(e);if(n===void 0)return o??G4;let i={transition:n};return o?{...i,...o}:i}var G4,U4,H4,Uw=m(()=>{Ow();G4={},U4=["all"],H4={}});var nf,of,j4,$4,Hw,Vp,Vw=m(()=>{"use client";nf=p(Q(),1);eu();dC();pC();Qw();kw();Nw();Hp();Uw();of=p(O(),1),j4=e=>{let{color:t,fontSize:r,classes:n}=e,o={root:["root",t!=="inherit"&&`color${qa(t)}`,`fontSize${qa(r)}`]};return tu(o,Lw,n)},$4=Gp("svg",{name:"MuiSvgIcon",slot:"Root",overridesResolver:(e,t)=>{let{ownerState:r}=e;return[t.root,r.color!=="inherit"&&t[`color${qa(r.color)}`],t[`fontSize${qa(r.fontSize)}`]]}})(_w(({theme:e})=>({userSelect:"none",width:"1em",height:"1em",display:"inline-block",flexShrink:0,...Gw(e,"fill",{duration:(e.vars??e).transitions?.duration?.shorter}),variants:[{props:t=>!t.hasSvgAsChild,style:{fill:"currentColor"}},{props:{fontSize:"inherit"},style:{fontSize:"inherit"}},{props:{fontSize:"small"},style:{fontSize:e.typography?.pxToRem?.(20)||"1.25rem"}},{props:{fontSize:"medium"},style:{fontSize:e.typography?.pxToRem?.(24)||"1.5rem"}},{props:{fontSize:"large"},style:{fontSize:e.typography?.pxToRem?.(35)||"2.1875rem"}},...Object.entries((e.vars??e).palette).filter(([,t])=>t&&t.main).map(([t])=>({props:{color:t},style:{color:(e.vars??e).palette?.[t]?.main}})),{props:{color:"action"},style:{color:(e.vars??e).palette?.action?.active}},{props:{color:"disabled"},style:{color:(e.vars??e).palette?.action?.disabled}},{props:{color:"inherit"},style:{color:void 0}}]}))),Hw=nf.forwardRef(function(t,r){let n=Up({props:t,name:"MuiSvgIcon"}),{children:o,className:i,color:s="inherit",component:a="svg",fontSize:c="medium",htmlColor:l,inheritViewBox:u=!1,titleAccess:d,viewBox:A="0 0 24 24",...f}=n,g=nf.isValidElement(o)&&o.type==="svg",h={...n,color:s,component:a,fontSize:c,instanceFontSize:t.fontSize,inheritViewBox:u,viewBox:A,hasSvgAsChild:g},x={};u||(x.viewBox=A);let w=j4(h);return(0,of.jsxs)($4,{as:a,className:as(w.root,i),focusable:"false",color:l,"aria-hidden":d?void 0:!0,role:d?"img":void 0,ref:r,...x,...f,...g&&o.props,ownerState:h,children:[g?o.props.children:o,d?(0,of.jsx)("title",{children:d}):null]})});Hw.muiName="SvgIcon";Vp=Hw});function W(e,t){function r(n,o){return(0,jw.jsx)(Vp,{"data-testid":void 0,ref:o,...n,children:e})}return r.muiName=Vp.muiName,sf.memo(sf.forwardRef(r))}var sf,jw,$w=m(()=>{"use client";sf=p(Q(),1);Vw();jw=p(O(),1)});var Ww=m(()=>{$w();Hp()});var we=m(()=>{"use client";Ww()});var Y=X((xee,zw)=>{zw.exports=JBrowseExports["mobx-react"]});var Ut=X((Cee,Jw)=>{Jw.exports=JBrowseExports["tss-react/mui"]});var jp=X((Iee,Zw)=>{Zw.exports=JBrowseExports["@jbrowse/core/pluggableElementTypes"]});var Ls=X((vee,rI)=>{rI.exports=JBrowseExports.mobx});function cf(e){let{scrollX:t,msaAreaWidth:r,minimapHeight:n,colWidth:o,numColumns:i}=e,s=r/i/o,a=-t,c=a*s,l=(a+r)*s,u=Math.max(l-c,20),d=n-12,A=`${c+u},0 ${c},0 0,${d} ${r},${d}`;return{unit:s,s:c,w:u,polygonHeight:d,polygonPoints:A}}var $p=m(()=>{});var li,nI,W4,oI,iI=m(()=>{li=p(Q(),1),nI=p(Y(),1);$p();W4=(0,nI.observer)(({model:e})=>{let{msaAreaWidth:t}=e,{s:r,w:n,polygonPoints:o}=cf(e),i="rgb(66, 119, 127)",s=.3;return li.default.createElement(li.default.Fragment,null,li.default.createElement("rect",{x:0,y:0,width:t,height:12,stroke:"#555",fill:"none"}),li.default.createElement("rect",{x:Math.max(0,r),y:0,width:n,height:12,fill:i,fillOpacity:s,stroke:"#555"}),li.default.createElement("g",{transform:`translate(0 ${12})`},li.default.createElement("polygon",{fill:i,fillOpacity:s,points:o})))}),oI=W4});var Wp,Yp,sI,aI,lf,uf,ui,cI,ff,lI,uI,fI,dI,AI,mI,pI,gI,Bc=m(()=>{Wp=new Set(["exon","CDS","five_prime_UTR","three_prime_UTR","UTR","intron"]),Yp=["#9fb6d4","#d4dcea"],sI=!0,aI=!1,lf=.2,uf=1,ui=80,cI=!0,ff="maeditor",lI=!0,uI=!0,fI=!1,dI=400,AI=300,mI=!0,pI=!0,gI=!0});function Ps({model:e,offsetY:t,blockSizeY:r}){let{leaves:n,rowHeight:o}=e,i=Math.max(0,Math.floor((t-o)/o)),s=Math.max(0,Math.ceil((t+r+o)/o));return n.slice(i,s)}var df=m(()=>{});function Af({model:e,offsetX:t,offsetY:r,ctx:n,highResScaleFactorOverride:o,blockSizeXOverride:i,blockSizeYOverride:s}){let{blockSize:a,rowHeight:c,highResScaleFactor:l,actuallyShowDomains:u}=e;if(u){let d=o??l,A=i??a,f=s??a;n.resetTransform(),n.scale(d,d),n.translate(-t,c/2-r),q4({model:e,ctx:n,visibleLeaves:Ps({model:e,offsetY:r,blockSizeY:f}),offsetX:t,blockWidth:A})}}function q4({model:e,ctx:t,visibleLeaves:r,offsetX:n,blockWidth:o}){let{subFeatureRows:i,colWidth:s,rowHeight:a,fillPalette:c,strokePalette:l,segmentLabels:u,showMsaLetters:d,domainBands:A}=e,f=i?4:a,g=!d&&!i&&f>=9,h=f+s,x=n-h,w=n+o+h;for(let y=0,v=r.length;y<v;y++){let b=r[y],I=b.x,S=A.get(b.data.name);if(S)for(let{annotation:B,startCol:R,endCol:D,stackIndex:L}of S){let{accession:P,strand:C}=B,M=R*s,k=s*(D-R);if(M+k>=x&&M<=w){let G=I-a+(i?L*f:0);if(t.fillStyle=c[P],t.strokeStyle=l[P],C===void 0){t.fillRect(M,G,k,f),t.strokeRect(M,G,k,f);let j=g?u.get(P):void 0;if(j!==void 0&&y===0){let oe=Math.min(f-2,11);t.font=`${oe}px sans-serif`,t.measureText(j).width+2<=k&&(t.fillStyle="#222",t.textAlign="center",t.textBaseline="middle",t.fillText(j,M+k/2,G+f/2))}}else z4({ctx:t,x:M,t:G,w:k,h:f,strand:C})}}}}function z4({ctx:e,x:t,t:r,w:n,h:o,strand:i}){let s=i>0?1:-1,a=i>0?t:t+n,c=i>0?t+n:t;e.beginPath(),e.moveTo(a,r),e.lineTo(c,r),e.lineTo(c+s*o,r+o/2),e.lineTo(c,r+o),e.lineTo(a,r+o),e.closePath(),e.fill(),e.stroke()}var qp=m(()=>{Bc();df()});function pn(e,t,r=!1){e.font=e.font.replace(/(?:bold )?[\d.]+px/,`${r?"bold ":""}${t}px`)}var Os=m(()=>{});var J4,Hn,lt,Er,II,hI,zp,K4,mf,SI,vI,yI,xI,CI,Tc,X4,Z4,eG,tG,Xp,EI,rG,Jp,Kp,bI,Zp,it,wI,pf,Mc=m(()=>{J4={grad:.9,turn:360,rad:360/(2*Math.PI)},Hn=function(e){return typeof e=="string"?e.length>0:typeof e=="number"},lt=function(e,t,r){return t===void 0&&(t=0),r===void 0&&(r=Math.pow(10,t)),Math.round(r*e)/r+0},Er=function(e,t,r){return t===void 0&&(t=0),r===void 0&&(r=1),e>r?r:e>t?e:t},II=function(e){return(e=isFinite(e)?e%360:0)>0?e:e+360},hI=function(e){return{r:Er(e.r,0,255),g:Er(e.g,0,255),b:Er(e.b,0,255),a:Er(e.a)}},zp=function(e){return{r:lt(e.r),g:lt(e.g),b:lt(e.b),a:lt(e.a,3)}},K4=/^#([0-9a-f]{3,8})$/i,mf=function(e){var t=e.toString(16);return t.length<2?"0"+t:t},SI=function(e){var t=e.r,r=e.g,n=e.b,o=e.a,i=Math.max(t,r,n),s=i-Math.min(t,r,n),a=s?i===t?(r-n)/s:i===r?2+(n-t)/s:4+(t-r)/s:0;return{h:60*(a<0?a+6:a),s:i?s/i*100:0,v:i/255*100,a:o}},vI=function(e){var t=e.h,r=e.s,n=e.v,o=e.a;t=t/360*6,r/=100,n/=100;var i=Math.floor(t),s=n*(1-r),a=n*(1-(t-i)*r),c=n*(1-(1-t+i)*r),l=i%6;return{r:255*[n,a,s,s,c,n][l],g:255*[c,n,n,a,s,s][l],b:255*[s,s,c,n,n,a][l],a:o}},yI=function(e){return{h:II(e.h),s:Er(e.s,0,100),l:Er(e.l,0,100),a:Er(e.a)}},xI=function(e){return{h:lt(e.h),s:lt(e.s),l:lt(e.l),a:lt(e.a,3)}},CI=function(e){return vI((r=(t=e).s,{h:t.h,s:(r*=((n=t.l)<50?n:100-n)/100)>0?2*r/(n+r)*100:0,v:n+r,a:t.a}));var t,r,n},Tc=function(e){return{h:(t=SI(e)).h,s:(o=(200-(r=t.s))*(n=t.v)/100)>0&&o<200?r*n/100/(o<=100?o:200-o)*100:0,l:o/2,a:t.a};var t,r,n,o},X4=/^hsla?\(\s*([+-]?\d*\.?\d+)(deg|rad|grad|turn)?\s*,\s*([+-]?\d*\.?\d+)%\s*,\s*([+-]?\d*\.?\d+)%\s*(?:,\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,Z4=/^hsla?\(\s*([+-]?\d*\.?\d+)(deg|rad|grad|turn)?\s+([+-]?\d*\.?\d+)%\s+([+-]?\d*\.?\d+)%\s*(?:\/\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,eG=/^rgba?\(\s*([+-]?\d*\.?\d+)(%)?\s*,\s*([+-]?\d*\.?\d+)(%)?\s*,\s*([+-]?\d*\.?\d+)(%)?\s*(?:,\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,tG=/^rgba?\(\s*([+-]?\d*\.?\d+)(%)?\s+([+-]?\d*\.?\d+)(%)?\s+([+-]?\d*\.?\d+)(%)?\s*(?:\/\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,Xp={string:[[function(e){var t=K4.exec(e);return t?(e=t[1]).length<=4?{r:parseInt(e[0]+e[0],16),g:parseInt(e[1]+e[1],16),b:parseInt(e[2]+e[2],16),a:e.length===4?lt(parseInt(e[3]+e[3],16)/255,2):1}:e.length===6||e.length===8?{r:parseInt(e.substr(0,2),16),g:parseInt(e.substr(2,2),16),b:parseInt(e.substr(4,2),16),a:e.length===8?lt(parseInt(e.substr(6,2),16)/255,2):1}:null:null},"hex"],[function(e){var t=eG.exec(e)||tG.exec(e);return t?t[2]!==t[4]||t[4]!==t[6]?null:hI({r:Number(t[1])/(t[2]?100/255:1),g:Number(t[3])/(t[4]?100/255:1),b:Number(t[5])/(t[6]?100/255:1),a:t[7]===void 0?1:Number(t[7])/(t[8]?100:1)}):null},"rgb"],[function(e){var t=X4.exec(e)||Z4.exec(e);if(!t)return null;var r,n,o=yI({h:(r=t[1],n=t[2],n===void 0&&(n="deg"),Number(r)*(J4[n]||1)),s:Number(t[3]),l:Number(t[4]),a:t[5]===void 0?1:Number(t[5])/(t[6]?100:1)});return CI(o)},"hsl"]],object:[[function(e){var t=e.r,r=e.g,n=e.b,o=e.a,i=o===void 0?1:o;return Hn(t)&&Hn(r)&&Hn(n)?hI({r:Number(t),g:Number(r),b:Number(n),a:Number(i)}):null},"rgb"],[function(e){var t=e.h,r=e.s,n=e.l,o=e.a,i=o===void 0?1:o;if(!Hn(t)||!Hn(r)||!Hn(n))return null;var s=yI({h:Number(t),s:Number(r),l:Number(n),a:Number(i)});return CI(s)},"hsl"],[function(e){var t=e.h,r=e.s,n=e.v,o=e.a,i=o===void 0?1:o;if(!Hn(t)||!Hn(r)||!Hn(n))return null;var s=(function(a){return{h:II(a.h),s:Er(a.s,0,100),v:Er(a.v,0,100),a:Er(a.a)}})({h:Number(t),s:Number(r),v:Number(n),a:Number(i)});return vI(s)},"hsv"]]},EI=function(e,t){for(var r=0;r<t.length;r++){var n=t[r][0](e);if(n)return[n,t[r][1]]}return[null,void 0]},rG=function(e){return typeof e=="string"?EI(e.trim(),Xp.string):typeof e=="object"&&e!==null?EI(e,Xp.object):[null,void 0]},Jp=function(e,t){var r=Tc(e);return{h:r.h,s:Er(r.s+100*t,0,100),l:r.l,a:r.a}},Kp=function(e){return(299*e.r+587*e.g+114*e.b)/1e3/255},bI=function(e,t){var r=Tc(e);return{h:r.h,s:r.s,l:Er(r.l+100*t,0,100),a:r.a}},Zp=(function(){function e(t){this.parsed=rG(t)[0],this.rgba=this.parsed||{r:0,g:0,b:0,a:1}}return e.prototype.isValid=function(){return this.parsed!==null},e.prototype.brightness=function(){return lt(Kp(this.rgba),2)},e.prototype.isDark=function(){return Kp(this.rgba)<.5},e.prototype.isLight=function(){return Kp(this.rgba)>=.5},e.prototype.toHex=function(){return t=zp(this.rgba),r=t.r,n=t.g,o=t.b,s=(i=t.a)<1?mf(lt(255*i)):"","#"+mf(r)+mf(n)+mf(o)+s;var t,r,n,o,i,s},e.prototype.toRgb=function(){return zp(this.rgba)},e.prototype.toRgbString=function(){return t=zp(this.rgba),r=t.r,n=t.g,o=t.b,(i=t.a)<1?"rgba("+r+", "+n+", "+o+", "+i+")":"rgb("+r+", "+n+", "+o+")";var t,r,n,o,i},e.prototype.toHsl=function(){return xI(Tc(this.rgba))},e.prototype.toHslString=function(){return t=xI(Tc(this.rgba)),r=t.h,n=t.s,o=t.l,(i=t.a)<1?"hsla("+r+", "+n+"%, "+o+"%, "+i+")":"hsl("+r+", "+n+"%, "+o+"%)";var t,r,n,o,i},e.prototype.toHsv=function(){return t=SI(this.rgba),{h:lt(t.h),s:lt(t.s),v:lt(t.v),a:lt(t.a,3)};var t},e.prototype.invert=function(){return it({r:255-(t=this.rgba).r,g:255-t.g,b:255-t.b,a:t.a});var t},e.prototype.saturate=function(t){return t===void 0&&(t=.1),it(Jp(this.rgba,t))},e.prototype.desaturate=function(t){return t===void 0&&(t=.1),it(Jp(this.rgba,-t))},e.prototype.grayscale=function(){return it(Jp(this.rgba,-1))},e.prototype.lighten=function(t){return t===void 0&&(t=.1),it(bI(this.rgba,t))},e.prototype.darken=function(t){return t===void 0&&(t=.1),it(bI(this.rgba,-t))},e.prototype.rotate=function(t){return t===void 0&&(t=15),this.hue(this.hue()+t)},e.prototype.alpha=function(t){return typeof t=="number"?it({r:(r=this.rgba).r,g:r.g,b:r.b,a:t}):lt(this.rgba.a,3);var r},e.prototype.hue=function(t){var r=Tc(this.rgba);return typeof t=="number"?it({h:t,s:r.s,l:r.l,a:r.a}):lt(r.h)},e.prototype.isEqual=function(t){return this.toHex()===it(t).toHex()},e})(),it=function(e){return e instanceof Zp?e:new Zp(e)},wI=[],pf=function(e){e.forEach(function(t){wI.indexOf(t)<0&&(t(Zp,Xp),wI.push(t))})}});function BI(e){e.prototype.luminance=function(){return t=tg(this.rgba),(r=2)===void 0&&(r=0),n===void 0&&(n=Math.pow(10,r)),Math.round(n*t)/n+0;var t,r,n},e.prototype.contrast=function(t){t===void 0&&(t="#FFF");var r,n,o,i,s,a,c,l=t instanceof e?t:new e(t);return i=this.rgba,s=l.toRgb(),a=tg(i),c=tg(s),r=a>c?(a+.05)/(c+.05):(c+.05)/(a+.05),(n=2)===void 0&&(n=0),o===void 0&&(o=Math.pow(10,n)),Math.floor(o*r)/o+0},e.prototype.isReadable=function(t,r){return t===void 0&&(t="#FFF"),r===void 0&&(r={}),this.contrast(t)>=(a=(s=(n=r).size)===void 0?"normal":s,(i=(o=n.level)===void 0?"AA":o)==="AAA"&&a==="normal"?7:i==="AA"&&a==="large"?3:4.5);var n,o,i,s,a}}var eg,tg,TI=m(()=>{eg=function(e){var t=e/255;return t<.04045?t/12.92:Math.pow((t+.055)/1.055,2.4)},tg=function(e){return .2126*eg(e.r)+.7152*eg(e.g)+.0722*eg(e.b)}});function gf(e,t){var r={white:"#ffffff",bisque:"#ffe4c4",blue:"#0000ff",cadetblue:"#5f9ea0",chartreuse:"#7fff00",chocolate:"#d2691e",coral:"#ff7f50",antiquewhite:"#faebd7",aqua:"#00ffff",azure:"#f0ffff",whitesmoke:"#f5f5f5",papayawhip:"#ffefd5",plum:"#dda0dd",blanchedalmond:"#ffebcd",black:"#000000",gold:"#ffd700",goldenrod:"#daa520",gainsboro:"#dcdcdc",cornsilk:"#fff8dc",cornflowerblue:"#6495ed",burlywood:"#deb887",aquamarine:"#7fffd4",beige:"#f5f5dc",crimson:"#dc143c",cyan:"#00ffff",darkblue:"#00008b",darkcyan:"#008b8b",darkgoldenrod:"#b8860b",darkkhaki:"#bdb76b",darkgray:"#a9a9a9",darkgreen:"#006400",darkgrey:"#a9a9a9",peachpuff:"#ffdab9",darkmagenta:"#8b008b",darkred:"#8b0000",darkorchid:"#9932cc",darkorange:"#ff8c00",darkslateblue:"#483d8b",gray:"#808080",darkslategray:"#2f4f4f",darkslategrey:"#2f4f4f",deeppink:"#ff1493",deepskyblue:"#00bfff",wheat:"#f5deb3",firebrick:"#b22222",floralwhite:"#fffaf0",ghostwhite:"#f8f8ff",darkviolet:"#9400d3",magenta:"#ff00ff",green:"#008000",dodgerblue:"#1e90ff",grey:"#808080",honeydew:"#f0fff0",hotpink:"#ff69b4",blueviolet:"#8a2be2",forestgreen:"#228b22",lawngreen:"#7cfc00",indianred:"#cd5c5c",indigo:"#4b0082",fuchsia:"#ff00ff",brown:"#a52a2a",maroon:"#800000",mediumblue:"#0000cd",lightcoral:"#f08080",darkturquoise:"#00ced1",lightcyan:"#e0ffff",ivory:"#fffff0",lightyellow:"#ffffe0",lightsalmon:"#ffa07a",lightseagreen:"#20b2aa",linen:"#faf0e6",mediumaquamarine:"#66cdaa",lemonchiffon:"#fffacd",lime:"#00ff00",khaki:"#f0e68c",mediumseagreen:"#3cb371",limegreen:"#32cd32",mediumspringgreen:"#00fa9a",lightskyblue:"#87cefa",lightblue:"#add8e6",midnightblue:"#191970",lightpink:"#ffb6c1",mistyrose:"#ffe4e1",moccasin:"#ffe4b5",mintcream:"#f5fffa",lightslategray:"#778899",lightslategrey:"#778899",navajowhite:"#ffdead",navy:"#000080",mediumvioletred:"#c71585",powderblue:"#b0e0e6",palegoldenrod:"#eee8aa",oldlace:"#fdf5e6",paleturquoise:"#afeeee",mediumturquoise:"#48d1cc",mediumorchid:"#ba55d3",rebeccapurple:"#663399",lightsteelblue:"#b0c4de",mediumslateblue:"#7b68ee",thistle:"#d8bfd8",tan:"#d2b48c",orchid:"#da70d6",mediumpurple:"#9370db",purple:"#800080",pink:"#ffc0cb",skyblue:"#87ceeb",springgreen:"#00ff7f",palegreen:"#98fb98",red:"#ff0000",yellow:"#ffff00",slateblue:"#6a5acd",lavenderblush:"#fff0f5",peru:"#cd853f",palevioletred:"#db7093",violet:"#ee82ee",teal:"#008080",slategray:"#708090",slategrey:"#708090",aliceblue:"#f0f8ff",darkseagreen:"#8fbc8f",darkolivegreen:"#556b2f",greenyellow:"#adff2f",seagreen:"#2e8b57",seashell:"#fff5ee",tomato:"#ff6347",silver:"#c0c0c0",sienna:"#a0522d",lavender:"#e6e6fa",lightgreen:"#90ee90",orange:"#ffa500",orangered:"#ff4500",steelblue:"#4682b4",royalblue:"#4169e1",turquoise:"#40e0d0",yellowgreen:"#9acd32",salmon:"#fa8072",saddlebrown:"#8b4513",sandybrown:"#f4a460",rosybrown:"#bc8f8f",darksalmon:"#e9967a",lightgoldenrodyellow:"#fafad2",snow:"#fffafa",lightgrey:"#d3d3d3",lightgray:"#d3d3d3",dimgray:"#696969",dimgrey:"#696969",olivedrab:"#6b8e23",olive:"#808000"},n={};for(var o in r)n[r[o]]=o;var i={};e.prototype.toName=function(s){if(!(this.rgba.a||this.rgba.r||this.rgba.g||this.rgba.b))return"transparent";var a,c,l=n[this.toHex()];if(l)return l;if(s?.closest){var u=this.toRgb(),d=1/0,A="black";if(!i.length)for(var f in r)i[f]=new e(r[f]).toRgb();for(var g in r){var h=(a=u,c=i[g],Math.pow(a.r-c.r,2)+Math.pow(a.g-c.g,2)+Math.pow(a.b-c.b,2));h<d&&(d=h,A=g)}return A}},t.string.push([function(s){var a=s.toLowerCase(),c=a==="transparent"?"#0000":r[a];return c?new e(c).toRgb():null},"name"])}var rg=m(()=>{});function RI(e,t){let r=`${e}|${t}`,n=MI.get(r);if(n!==void 0)return n;let o=it(e);if(!o.isReadable(t)){let s=it(t).luminance()<.5;for(let a=0;a<40&&!o.isReadable(t);a++)o=s?o.lighten(.05):o.darken(.05)}let i=o.toHex();return MI.set(r,i),i}function Gs(e,t){return Object.fromEntries(Object.entries(e).map(t))}function Rc(e,t){return Gs(e,([r,n])=>[r,t.palette.getContrastText(it(n).toHex())])}function ng(e,t){if(e.length===0)return t;let r=[],n=0;for(let o of e)o>n&&r.push(t.slice(n,o)),n=o+1;return n<t.length&&r.push(t.slice(n)),r.join("")}function QI(e,t){let r=[],n=e.length,o=0,i=0,s=-1,a=[];for(let c=0;c<t.length;c++)i<n&&e[i]===c?(t.charCodeAt(c)-45>>>0<=1||(s===o?a.push(t[c]):(a.length>0&&r.push({pos:s,letters:a.join("")}),s=o,a=[t[c]])),i++):o++;return a.length>0&&r.push({pos:s,letters:a.join("")}),r}function og(e){return e.end-e.start}function hf(e){return e==="-"||e==="."}var MI,ho=m(()=>{Mc();TI();rg();pf([gf,BI]);MI=new Map});function Qc({offsetX:e,blockWidth:t,colWidth:r}){return{xStart:Math.max(0,Math.floor(e/r)),xEnd:Math.max(0,Math.ceil((e+t)/r))}}var ig=m(()=>{});function yf({model:e,offsetX:t,offsetY:r,contrastScheme:n,ctx:o,theme:i,highResScaleFactorOverride:s,blockSizeXOverride:a,blockSizeYOverride:c}){let{colWidth:l,blockSize:u,rowHeight:d,fontSize:A,highResScaleFactor:f,actuallyShowDomains:g,bgColor:h}=e,x=s??f,w=a??u,y=c??u;o.resetTransform(),o.scale(x,x),o.translate(-t,d/2-r),o.textAlign="center",o.textBaseline="alphabetic",pn(o,A,!h);let{xStart:v,xEnd:b}=Qc({offsetX:t,blockWidth:w,colWidth:l}),I=Ps({model:e,offsetY:r,blockSizeY:y}),{relativeTo:S,columns:B}=e,R=S?B.get(S)?.slice(v,b):null;iG({model:e,ctx:o,theme:i,contrastScheme:n,xStart:v,xEnd:b,visibleLeaves:I,referenceSeq:R,drawTiles:!g}),sG({model:e,ctx:o,xStart:v,xEnd:b,visibleLeaves:I}),o.resetTransform()}function nG(e){let{colorSchemeName:t,colorScheme:r,colClustalX:n,colConsensus:o}=e;return t==="clustalx_protein_dynamic"?(i,s)=>n[i][s]:t==="percent_identity_dynamic"?(i,s)=>{let a=o[i];return s===a.letter?a.color:void 0}:(i,s)=>r[s]}function oG(e,t){return new Map(Object.entries(e.fillPalette).map(([r,n])=>[r,t.palette.getContrastText(n)]))}function iG({model:e,ctx:t,theme:r,contrastScheme:n,visibleLeaves:o,xStart:i,xEnd:s,referenceSeq:a,drawTiles:c}){let{bgColor:l,columns:u,colWidth:d,rowHeight:A,relativeTo:f,showMsaLetters:g,subFeatureRows:h,domainBandsByStart:x}=e,w=c&&l;if(w||g){let y=nG(e),v=i*d,b=d/2,I=A/4,S=!c&&!h,B=S?oG(e,r):void 0;for(let R=0,D=o.length;R<D;R++){let L=o[R],{name:P}=L.data,C=L.x,M=u.get(P)?.slice(i,s);if(M){let k=C-A,G=C-I,j=S?x.get(P):void 0,oe=0;for(let te=0,kr=M.length;te<kr;te++){let ot=i+te,Ae=M[te],Dr=te*d+v,mr=a&&P!==f&&Ae===a[te],nn=y(ot,Ae);if(w&&(t.fillStyle=mr?r.palette.action.hover:nn||r.palette.background.default,t.fillRect(Dr,k,d,A)),g){for(;j&&oe<j.length&&j[oe].endCol<=ot;)oe++;let Dn=j?.[oe];t.fillStyle=Dn&&Dn.startCol<=ot?B.get(Dn.annotation.accession):w?n[Ae]??"black":!c||!nn?r.palette.text.primary:RI(nn,r.palette.background.default),t.fillText(mr?".":Ae,Dr+b,G)}}}}}}function sG({model:e,ctx:t,visibleLeaves:r,xStart:n,xEnd:o}){let{bgColor:i,hideGapsEffective:s}=e;s&&(t.lineWidth=1,t.strokeStyle="#f0f",_I({visibleLeaves:r,xStart:n,ctx:t,model:e,xEnd:o,offset:0}),t.strokeStyle=i?"#fff":"#000",_I({visibleLeaves:r,xStart:n,ctx:t,model:e,xEnd:o,offset:-1}))}function _I({model:e,ctx:t,visibleLeaves:r,xStart:n,xEnd:o,offset:i}){let{colWidth:a,rowHeight:c,insertionPositions:l}=e;for(let u of r){let{name:d}=u.data,A=l.get(d);if(A){let f=u.x;for(let{pos:g}of A)if(g>=n&&g<o){let h=g*a,x=f-c,w=f;t.beginPath(),t.moveTo(h+i,x+i);let y=x,v=!0;for(;y<w;){let b=Math.min(y+2,w),I=v?h+1:h-1;t.lineTo(I+i,b+i),y=b,v=!v}t.stroke()}}}}var sg=m(()=>{Os();ho();df();ig()});function ag({ctx:e,values:t,color:r,colWidth:n,trackHeight:o,offsetX:i,blockSize:s}){let{xStart:a,xEnd:c}=Qc({offsetX:i,blockWidth:s,colWidth:n});e.fillStyle=r;for(let l=a;l<c&&l<t.length;l++){let d=t[l]*o,A=l*n;e.fillRect(A,o-d,n,d)}}function cg(e,t){return t==="property-conservation"?e.propertyConservation:e.conservation}function lg({ctx:e,data:t,colorScheme:r,contrastScheme:n,bgColor:o,textColor:i,colWidth:s,rowHeight:a,offsetX:c,blockSize:l}){let{xStart:u,xEnd:d}=Qc({offsetX:c,blockWidth:l,colWidth:s}),A=t?.slice(u,d),f=a>=10&&s>=a/2;for(let g=0;A&&g<A.length;g++){let h=A[g],x=h.toUpperCase(),w=r[x],y=(u+g)*s,v=o&&!!w;v&&(e.fillStyle=w,e.fillRect(y,0,s,a)),f&&(e.fillStyle=v?n[x]??"black":i,e.fillText(h,y+s/2,a/2+1))}}function aG({model:e,ctx:t,track:r,offsetX:n,offsetY:o,trackHeight:i,blockSizeXOverride:s,highResScaleFactorOverride:a}){let{blockSize:c,colWidth:l,highResScaleFactor:u}=e,d=s??c,A=a??u;t.resetTransform(),t.scale(A,A),t.translate(-n,o),ag({ctx:t,values:cg(e,r.model.id),color:r.model.barColor??"gray",colWidth:l,trackHeight:i,offsetX:n,blockSize:d}),t.resetTransform()}function cG({model:e,ctx:t,track:r,offsetX:n,offsetY:o,contrastScheme:i,theme:s,blockSizeXOverride:a,highResScaleFactorOverride:c}){let{blockSize:l,bgColor:u,colorScheme:d,colWidth:A,fontSize:f,rowHeight:g,highResScaleFactor:h}=e,{customColorScheme:x,data:w}=r.model,y=x??d,v=a??l,b=c??h;t.resetTransform(),t.scale(b,b),t.translate(-n,o),t.textAlign="center",pn(t,f),lg({ctx:t,data:w,colorScheme:y,contrastScheme:i,bgColor:u,textColor:s.palette.text.primary,colWidth:A,rowHeight:g,offsetX:n,blockSize:v}),t.resetTransform()}function kI({model:e,ctx:t,offsetX:r,contrastScheme:n,theme:o,blockSizeXOverride:i,highResScaleFactorOverride:s}){let{turnedOnTracks:a}=e,c=0;for(let l of a){let u=l.model.height;l.model.barColor!==void 0?aG({model:e,ctx:t,track:l,offsetX:r,offsetY:c,trackHeight:u,blockSizeXOverride:i,highResScaleFactorOverride:s}):cG({model:e,ctx:t,track:l,offsetX:r,offsetY:c,contrastScheme:n,theme:o,blockSizeXOverride:i,highResScaleFactorOverride:s}),c+=u}}var xf=m(()=>{Os();ig()});function uG(e){let t=[],r="",n="",o=!1;function i(){let s=o?n:r.trim();(s!==""||o)&&t.push({text:s,delim:!1,quoted:o}),r="",n="",o=!1}for(let s=0;s<e.length;s++){let a=e[s];if(a==="'")for(o=!0,s++;s<e.length;s++)if(e[s]!=="'")n+=e[s];else if(e[s+1]==="'")n+="'",s++;else break;else a==="("||a===")"||a===","||a===":"||a===";"?(i(),t.push({text:a,delim:!0,quoted:!1})):r+=a}return i(),t}function Cf(e,t={}){let r=[],n=uG(e),{postParenNumeric:o="auto"}=t,i=o==="length"||o==="auto"&&!n.some(a=>a.delim&&a.text===":"),s={};for(let a=0;a<n.length;a++){let c=n[a],l={};if(c.delim){switch(c.text){case"(":s.children=[l],r.push(s),s=l;break;case",":r.at(-1)?.children?.push(l),s=l;break;case")":s=r.pop();break;default:break}continue}let u=a>0?n[a-1]:void 0,d=u?.delim?u.text:void 0;d===":"?s.length=Number.parseFloat(c.text):d===")"?i&&!c.quoted&&lG.test(c.text)?s.length=Number.parseFloat(c.text):s.name=c.text:(d==="("||d===","||d===void 0)&&(s.name=c.text)}return s}var lG,DI=m(()=>{lG=/^-?\d+(\.\d+)?([eE][+-]?\d+)?$/});function fi(e){let t=[],r=[e];for(;r.length>0;){let n=r.pop();if(t.push(n),n.children)for(let o=n.children.length-1;o>=0;o--)r.push(n.children[o])}return t}function di(e){let t=[],r=[e];for(;r.length>0;){let n=r.pop();if(n.children)for(let o=n.children.length-1;o>=0;o--)r.push(n.children[o]);else t.push(n)}return t}function _c(e,t){let r=[{source:null,target:e}];for(;r.length>0;){let{source:n,target:o}=r.pop();if(n&&t(n,o),o.children)for(let i=o.children.length-1;i>=0;i--)r.push({source:o,target:o.children[i]})}}function Ef(e){let t=[];return _c(e,(r,n)=>{t.push({source:r,target:n})}),t}function Ai(e,t){for(let r of fi(e))t(r)}function ug(e,t){let r=[],n=[e];for(;n.length>0;){let o=n.pop();if(r.push(o),o.children)for(let i of o.children)n.push(i)}for(let o=r.length-1;o>=0;o--)t(r[o])}function fG(e){ug(e,t=>{let r=0;if(t.children)for(let n of t.children)n.height+1>r&&(r=n.height+1);t.height=r})}function fg(e,t){let r={data:e,children:null,parent:null,depth:0,height:0},n=[r];for(;n.length>0;){let o=n.pop(),i=t(o.data);if(i?.length){o.children=i.map(s=>({data:s,children:null,parent:o,depth:o.depth+1,height:0}));for(let s of o.children)n.push(s)}}return fG(r),r}function bf(e,t){return ug(e,r=>{let n=t(r.data);if(r.children)for(let o of r.children)n+=o.value;r.value=n}),e}function wf(e,t){let r=[e];for(;r.length>0;){let n=r.pop();if(n.children){n.children.sort(t);for(let o of n.children)r.push(o)}}return e}function Us(e,t){let r=[e];for(;r.length>0;){let n=r.pop();if(t(n))return n;if(n.children)for(let o=n.children.length-1;o>=0;o--)r.push(n.children[o])}}var NI=m(()=>{});var dg=m(()=>{DI();NI()});function LI(e,t){return fg(e,t)}function FI(e,t,r){let n=di(e),o=n.length,i=t/o;for(let l=0;l<o;l++)n[l].x=(l+.5)*i;let s=fi(e);for(let l=s.length-1;l>=0;l--){let u=s[l];if(u.children){let d=0;for(let A of u.children)d+=A.x;u.x=d/u.children.length}}let a=e.height,c=[{node:e,depth:0}];for(;c.length>0;){let{node:l,depth:u}=c.pop();if(l.y=a===0?r:u/a*r,l.children)for(let d of l.children)c.push({node:d,depth:u+1})}}function PI(e){e.children&&(kc(e),e._children=e.children,e.children=null)}function OI(e){let t=e._children??e.children,r=1/0,n=0;if(t){let o=t.map(i=>({node:i,acc:Math.max(i.data.length??0,0)}));for(;o.length>0;){let{node:i,acc:s}=o.pop(),a=i.children??i._children;if(a?.length)for(let c of a)o.push({node:c,acc:s+Math.max(c.data.length??0,0)});else r=Math.min(r,s),n=Math.max(n,s)}}return{min:r===1/0?0:r,max:n}}function kc(e){if(e.depthToLeaf===void 0){let t=fi(e);for(let r=t.length-1;r>=0;r--){let n=t[r];if(n.depthToLeaf===void 0){let o=0;if(n.children)for(let i of n.children)o=Math.max(o,1+i.depthToLeaf);n.depthToLeaf=o}}}return e.depthToLeaf}function GI(e){let t=0;for(let r of fi(e))t=Math.max(t,r.len||0);return t}function UI(e){let t=fi(e),r=new Map;for(let n=t.length-1;n>=0;n--){let o=t[n],i=0;if(o.children)for(let s of o.children)i=Math.max(i,r.get(s));r.set(o,(o.data.length||0)+i)}return r.get(e)}function HI(e,t,r){let n=[{node:e,y0:t}];for(;n.length>0;){let{node:o,y0:i}=n.pop(),s=i+Math.max(o.data.length||0,0);if(o.len=s*r,o.children)for(let a of o.children)n.push({node:a,y0:s})}}var Ag=m(()=>{dg()});function pg(e,t,r){return e>t-VI&&e<t+r+VI}function Dc(e,t,r,n){if(t)return e.len;if(n===0)return 0;let o=kc(e);return(n-o)/n*r}function dG({offsetY:e,ctx:t,model:r,theme:n,tipX:o,maxDepthToLeaf:i,blockSizeYOverride:s}){let{hierarchy:a,showBranchLenEffective:c,blockSize:l}=r,u=s??l;t.strokeStyle=n.palette.text.primary,_c(a,(d,A)=>{let f=d.x,g=A.x,h=Dc(A,c,o,i),x=Dc(d,c,o,i);if(h===void 0||x===void 0)return;let w=Math.min(f,g),y=Math.max(f,g);e+u>=w&&y>=e&&(t.beginPath(),t.moveTo(x,f),t.lineTo(x,g),t.lineTo(h,g),t.stroke())})}function AG({ctx:e,clickMap:t,offsetY:r,model:n,theme:o,tipX:i,maxDepthToLeaf:s,blockSizeYOverride:a}){let{hierarchy:c,showBranchLenEffective:l,collapsed:u,blockSize:d,rowHeight:A,fontSize:f,marginLeft:g}=n;if(u.length===0)return;let h=new Set(u),x=a??d,w=Math.max(2,A*.42);Ai(c,y=>{let{id:v,name:b}=y.data;if(h.has(v)){let I=Dc(y,l,i,s),S=y.x,B=pg(S,r,x),R=l?y.collapsedTipXFar??i:i;if(I!==void 0&&B&&R>I){e.beginPath(),e.moveTo(I,S),e.lineTo(R,S-w),e.lineTo(R,S+w),e.closePath(),e.fillStyle=o.palette.action.disabled,e.fill(),e.strokeStyle=o.palette.text.primary,e.stroke();let D=y.value;D!==void 0&&A>=8&&(e.fillStyle=o.palette.text.primary,e.textAlign="left",e.fillText(`${D}`,R+3,S+f/4));let L=b===v?"Collapsed clade":b;t?.insert({minX:I+g,maxX:R+g,minY:S-w,maxY:S+w,branch:!0,id:v,name:D===void 0?L:`${L} (${D} tips)`})}}})}function mG({ctx:e,clickMap:t,offsetY:r,model:n,tipX:o,maxDepthToLeaf:i,blockSizeYOverride:s}){let{hierarchy:a,showBranchLenEffective:c,collapsed:l,blockSize:u,marginLeft:d}=n,A=s??u,f=new Set(l);Ai(a,g=>{let h=Dc(g,c,o,i);if(h===void 0)return;let{data:x}=g,w=g.x,{id:y,name:v}=x;if(g.height>=1&&pg(w,r,A)){let b=f.has(y);e.strokeStyle="black",e.fillStyle=b?"black":"white",e.beginPath(),e.arc(h,w,mi,0,2*Math.PI),e.fill(),e.stroke(),b||t?.insert({minX:h-mi+d,maxX:h-mi+mg+d,minY:w-mi,maxY:w-mi+mg,branch:!0,id:y,name:v})}})}function pG({theme:e,model:t,offsetY:r,ctx:n,clickMap:o,tipX:i,maxDepthToLeaf:s,blockSizeYOverride:a}){let{fontSize:c,showBranchLenEffective:l,treeMetadata:u,blockSize:d,labelsAlignRight:A,drawTree:f,treeAreaWidth:g,treeAreaWidthMinusMargin:h,marginLeft:x,noTree:w,labelWidthMap:y,collapsed:v}=t,b=Ps({model:t,offsetY:r,blockSizeY:a??t.blockSize}),I=a??d,S=n.measureText("M").width;A?(n.textAlign="right",n.setLineDash([1,3]),n.strokeStyle=e.palette.text.primary):n.textAlign="start";for(let B of b){let{data:{name:R,id:D}}=B,L=B.x,P=u[R]?.genome||R;if(!(v.includes(D)&&R===D)&&pg(L,r,I)){let M=L+c/4,k=0;w||(k=Dc(B,l,i,s)??0);let G=y.get(R)??n.measureText(P).width;if(n.fillStyle=e.palette.text.primary,A){let oe=h-2;f&&!w&&(n.beginPath(),n.moveTo(k+mi+2,L),n.lineTo(oe-2-G,L),n.stroke()),n.fillText(P,oe,M),o?.insert({minX:g-G,maxX:g,minY:M-S,maxY:M,name:R,id:D})}else{let j=w?2:k+mg;n.fillText(P,j,M),o?.insert({minX:j+x,maxX:j+G+x,minY:M-S,maxY:M,name:R,id:D})}}}n.setLineDash([])}function Sf({model:e,clickMap:t,ctx:r,offsetY:n,theme:o,highResScaleFactorOverride:i,blockSizeYOverride:s}){t?.clear();let{noTree:a,drawTree:c,drawNodeBubbles:l,highResScaleFactor:u,fontSize:d,showTreeText:A,marginLeft:f,rowHeight:g}=e;r.resetTransform();let h=i??u;r.scale(h,h),r.translate(f,-n),pn(r,d);let{maxBranchLength:x,maxDepthToLeaf:w,showBranchLenEffective:y,treeWidth:v}=e,b=y?x:v;!a&&c&&(dG({ctx:r,offsetY:n,model:e,theme:o,tipX:b,maxDepthToLeaf:w,blockSizeYOverride:s}),AG({ctx:r,clickMap:t,offsetY:n,model:e,theme:o,tipX:b,maxDepthToLeaf:w,blockSizeYOverride:s}),l&&mG({ctx:r,offsetY:n,clickMap:t,model:e,tipX:b,maxDepthToLeaf:w,blockSizeYOverride:s})),A&&pG({ctx:r,offsetY:n,model:e,clickMap:t,theme:o,tipX:b,maxDepthToLeaf:w,blockSizeYOverride:s}),t?.finish()}var If,VI,mi,mg,vf=m(()=>{Ag();Os();df();If=600,VI=5,mi=2.5,mg=mi*2});var WI={};Bt(WI,{Context:()=>yg});function jI(e){return!e||typeof e=="string"?e:e+""}function Gr(e,t){let r=Object.keys(t);for(let n of r)e=e.replace(new RegExp("\\{"+n+"\\}","gi"),t[n]);return e}function gg(e){if(!e)throw new Error("cannot create a random attribute name for an undefined object");let t="ABCDEFGHIJKLMNOPQRSTUVWXTZabcdefghiklmnopqrstuvwxyz",r="";do{r="";for(let n=0;n<12;n++)r+=t[Math.floor(Math.random()*t.length)]}while(e[r]);return r}function gG(e,t=10){let r={},n=e.split(",");for(let o=0;o<n.length;o+=2){let i="&"+n[o+1]+";",s=parseInt(n[o],t);r[i]="&#"+s+";"}return r["\\xa0"]="&#160;",r}function hG(e){let t={left:"start",right:"end",center:"middle",start:"start",end:"end"};return t[e]||t.start}function yG(e){let t={alphabetic:"alphabetic",hanging:"hanging",top:"text-before-edge",bottom:"text-after-edge",middle:"central"};return t[e]||t.alphabetic}var $I,Nc,Lc,hg,yg,YI=m(()=>{$I=gG("50,nbsp,51,iexcl,52,cent,53,pound,54,curren,55,yen,56,brvbar,57,sect,58,uml,59,copy,5a,ordf,5b,laquo,5c,not,5d,shy,5e,reg,5f,macr,5g,deg,5h,plusmn,5i,sup2,5j,sup3,5k,acute,5l,micro,5m,para,5n,middot,5o,cedil,5p,sup1,5q,ordm,5r,raquo,5s,frac14,5t,frac12,5u,frac34,5v,iquest,60,Agrave,61,Aacute,62,Acirc,63,Atilde,64,Auml,65,Aring,66,AElig,67,Ccedil,68,Egrave,69,Eacute,6a,Ecirc,6b,Euml,6c,Igrave,6d,Iacute,6e,Icirc,6f,Iuml,6g,ETH,6h,Ntilde,6i,Ograve,6j,Oacute,6k,Ocirc,6l,Otilde,6m,Ouml,6n,times,6o,Oslash,6p,Ugrave,6q,Uacute,6r,Ucirc,6s,Uuml,6t,Yacute,6u,THORN,6v,szlig,70,agrave,71,aacute,72,acirc,73,atilde,74,auml,75,aring,76,aelig,77,ccedil,78,egrave,79,eacute,7a,ecirc,7b,euml,7c,igrave,7d,iacute,7e,icirc,7f,iuml,7g,eth,7h,ntilde,7i,ograve,7j,oacute,7k,ocirc,7l,otilde,7m,ouml,7n,divide,7o,oslash,7p,ugrave,7q,uacute,7r,ucirc,7s,uuml,7t,yacute,7u,thorn,7v,yuml,ci,fnof,sh,Alpha,si,Beta,sj,Gamma,sk,Delta,sl,Epsilon,sm,Zeta,sn,Eta,so,Theta,sp,Iota,sq,Kappa,sr,Lambda,ss,Mu,st,Nu,su,Xi,sv,Omicron,t0,Pi,t1,Rho,t3,Sigma,t4,Tau,t5,Upsilon,t6,Phi,t7,Chi,t8,Psi,t9,Omega,th,alpha,ti,beta,tj,gamma,tk,delta,tl,epsilon,tm,zeta,tn,eta,to,theta,tp,iota,tq,kappa,tr,lambda,ts,mu,tt,nu,tu,xi,tv,omicron,u0,pi,u1,rho,u2,sigmaf,u3,sigma,u4,tau,u5,upsilon,u6,phi,u7,chi,u8,psi,u9,omega,uh,thetasym,ui,upsih,um,piv,812,bull,816,hellip,81i,prime,81j,Prime,81u,oline,824,frasl,88o,weierp,88h,image,88s,real,892,trade,89l,alefsym,8cg,larr,8ch,uarr,8ci,rarr,8cj,darr,8ck,harr,8dl,crarr,8eg,lArr,8eh,uArr,8ei,rArr,8ej,dArr,8ek,hArr,8g0,forall,8g2,part,8g3,exist,8g5,empty,8g7,nabla,8g8,isin,8g9,notin,8gb,ni,8gf,prod,8gh,sum,8gi,minus,8gn,lowast,8gq,radic,8gt,prop,8gu,infin,8h0,ang,8h7,and,8h8,or,8h9,cap,8ha,cup,8hb,int,8hk,there4,8hs,sim,8i5,cong,8i8,asymp,8j0,ne,8j1,equiv,8j4,le,8j5,ge,8k2,sub,8k3,sup,8k4,nsub,8k6,sube,8k7,supe,8kl,oplus,8kn,otimes,8l5,perp,8m5,sdot,8o8,lceil,8o9,rceil,8oa,lfloor,8ob,rfloor,8p9,lang,8pa,rang,9ea,loz,9j0,spades,9j3,clubs,9j5,hearts,9j6,diams,ai,OElig,aj,oelig,b0,Scaron,b1,scaron,bo,Yuml,m6,circ,ms,tilde,802,ensp,803,emsp,809,thinsp,80c,zwnj,80d,zwj,80e,lrm,80f,rlm,80j,ndash,80k,mdash,80o,lsquo,80p,rsquo,80q,sbquo,80s,ldquo,80t,rdquo,80u,bdquo,810,dagger,811,Dagger,81g,permil,81p,lsaquo,81q,rsaquo,85c,euro",32),Nc={strokeStyle:{svgAttr:"stroke",canvas:"#000000",svg:"none",apply:"stroke"},fillStyle:{svgAttr:"fill",canvas:"#000000",svg:null,apply:"fill"},lineCap:{svgAttr:"stroke-linecap",canvas:"butt",svg:"butt",apply:"stroke"},lineJoin:{svgAttr:"stroke-linejoin",canvas:"miter",svg:"miter",apply:"stroke"},miterLimit:{svgAttr:"stroke-miterlimit",canvas:10,svg:4,apply:"stroke"},lineWidth:{svgAttr:"stroke-width",canvas:1,svg:1,apply:"stroke"},globalAlpha:{svgAttr:"opacity",canvas:1,svg:1,apply:"fill stroke"},font:{canvas:"10px sans-serif"},shadowColor:{canvas:"#000000"},shadowOffsetX:{canvas:0},shadowOffsetY:{canvas:0},shadowBlur:{canvas:0},textAlign:{canvas:"start"},textBaseline:{canvas:"alphabetic"},lineDash:{svgAttr:"stroke-dasharray",canvas:[],svg:null,apply:"stroke"}},Lc=class{__root;__ctx;constructor(t,r){this.__root=t,this.__ctx=r}addColorStop(t,r){let n=this.__ctx.__createElement("stop");if(n.setAttribute("offset",String(t)),jI(r).includes("rgba")){let i=/rgba\(\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d?\.?\d*)\s*\)/gi.exec(r);i&&(n.setAttribute("stop-color",Gr("rgb({r},{g},{b})",{r:i[1],g:i[2],b:i[3]})),n.setAttribute("stop-opacity",i[4]))}else n.setAttribute("stop-color",jI(r));this.__root.appendChild(n)}},hg=class{__root;__ctx;constructor(t,r){this.__root=t,this.__ctx=r}},yg=class{width;height;enableMirroring;canvas;__document;__ctx;__canvas;__root;__ids;__defs;__currentElement;__styleStack;__groupStack;__currentDefaultPath;__currentPosition;__transformMatrix;__transformMatrixStack;__currentElementsToStyle;__options;__id;__fontUnderline;__fontHref;strokeStyle;fillStyle;lineCap;lineJoin;miterLimit;lineWidth;globalAlpha;font;shadowColor;shadowOffsetX;shadowOffsetY;shadowBlur;textAlign;textBaseline;lineDash;constructor(t,r){let n={width:500,height:500,enableMirroring:!1},o;typeof t=="number"&&r!==void 0?o={...n,width:t,height:r}:t&&typeof t=="object"?o=t:o=n,this.width=o.width||n.width,this.height=o.height||n.height,this.enableMirroring=o.enableMirroring!==void 0?o.enableMirroring:n.enableMirroring,this.canvas=this,this.__document=o.document||document,o.ctx?this.__ctx=o.ctx:(this.__canvas=this.__document.createElement("canvas"),this.__ctx=this.__canvas.getContext("2d")),this.__setDefaultStyles(),this.__styleStack=[this.__getStyleState()],this.__groupStack=[],this.__root=this.__document.createElementNS("http://www.w3.org/2000/svg","svg"),this.__root.setAttribute("version","1.1"),this.__root.setAttribute("xmlns","http://www.w3.org/2000/svg"),this.__root.setAttributeNS("http://www.w3.org/2000/xmlns/","xmlns:xlink","http://www.w3.org/1999/xlink"),this.__root.setAttribute("width",String(this.width)),this.__root.setAttribute("height",String(this.height)),this.__ids={},this.__defs=this.__document.createElementNS("http://www.w3.org/2000/svg","defs"),this.__root.appendChild(this.__defs),this.__currentElement=this.__document.createElementNS("http://www.w3.org/2000/svg","g"),this.__root.appendChild(this.__currentElement),this.__currentDefaultPath="",this.__currentPosition={},this.__transformMatrix=new DOMMatrix,this.resetTransform(),this.__options=o,this.__id=Math.random().toString(16).substring(2,8)}__createElement(t,r={},n){let o=this.__document.createElementNS("http://www.w3.org/2000/svg",t);n&&(o.setAttribute("fill","none"),o.setAttribute("stroke","none"));for(let i of Object.keys(r))o.setAttribute(i,r[i]);return o}__setDefaultStyles(){for(let t of Object.keys(Nc))this[t]=Nc[t].canvas}__applyStyleState(t){for(let r of Object.keys(t))this[r]=t[r]}__getStyleState(){let t={};for(let r of Object.keys(Nc))t[r]=this[r];return t}__applyTransformation(t,r){let{a:n,b:o,c:i,d:s,e:a,f:c}=r||this.getTransform();t.setAttribute("transform",`matrix(${n} ${o} ${i} ${s} ${a} ${c})`)}__applyStyleToCurrentElement(t){let r=this.__currentElement,n=this.__currentElementsToStyle;if(n){r.setAttribute(t,""),r=n.element;for(let i of n.children)i.setAttribute(t,"")}let o=Object.keys(Nc);for(let i of o){let s=Nc[i],a=this[i];if(s.apply){if(a instanceof hg){if(a.__ctx)for(let c of Array.from(a.__ctx.__defs.childNodes)){let l=c.getAttribute("id");l&&(this.__ids[l]=l,this.__defs.appendChild(c))}r.setAttribute(s.apply,Gr("url(#{id})",{id:a.__root.getAttribute("id")}))}else if(a instanceof Lc)r.setAttribute(s.apply,Gr("url(#{id})",{id:a.__root.getAttribute("id")}));else if(s.apply.includes(t)&&s.svg!==a)if((s.svgAttr==="stroke"||s.svgAttr==="fill")&&a&&a.includes("rgba")){let l=/rgba\(\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d?\.?\d*)\s*\)/gi.exec(a);if(l){r.setAttribute(s.svgAttr,Gr("rgb({r},{g},{b})",{r:l[1],g:l[2],b:l[3]}));let u=Number(l[4]),d=this.globalAlpha;d!=null&&(u*=d),r.setAttribute(s.svgAttr+"-opacity",String(u))}}else{let c=s.svgAttr,l=a;if(i==="globalAlpha"){if(c=t+"-"+s.svgAttr,r.getAttribute(c))continue}else if(i==="lineWidth"){let u=this.__getTransformScale();l=a*Math.max(u.x,u.y)}r.setAttribute(c,l)}}}}__closestGroupOrSvg(t){return t=t||this.__currentElement,t.nodeName==="g"||t.nodeName==="svg"?t:this.__closestGroupOrSvg(t.parentNode)}getSerializedSvg(t){let r=new XMLSerializer().serializeToString(this.__root);if(/xmlns="http:\/\/www\.w3\.org\/2000\/svg".+xmlns="http:\/\/www\.w3\.org\/2000\/svg/gi.test(r)&&(r=r.replace('xmlns="http://www.w3.org/2000/svg','xmlns:xlink="http://www.w3.org/1999/xlink')),t)for(let o of Object.keys($I)){let i=new RegExp(o,"gi");i.test(r)&&(r=r.replace(i,$I[o]))}return r}getSvg(){return this.__root}save(){let t=this.__createElement("g"),r=this.__closestGroupOrSvg();this.__groupStack.push(r),r.appendChild(t),this.__currentElement=t;let n=this.__getStyleState();this.__styleStack.push(n),this.__transformMatrixStack||(this.__transformMatrixStack=[]),this.__transformMatrixStack.push(this.getTransform())}restore(){this.__currentElement=this.__groupStack.pop(),this.__currentElementsToStyle=void 0,this.__currentElement||(this.__currentElement=this.__root.childNodes[1]);let t=this.__styleStack.pop();this.__applyStyleState(t),this.__transformMatrixStack&&this.__transformMatrixStack.length>0&&this.setTransform(this.__transformMatrixStack.pop())}beginPath(){this.__currentDefaultPath="",this.__currentPosition={};let t=this.__createElement("path",{},!0);this.__closestGroupOrSvg().appendChild(t),this.__currentElement=t}__applyCurrentDefaultPath(){let t=this.__currentElement;t.nodeName==="path"&&t.setAttribute("d",this.__currentDefaultPath)}__addPathCommand(t){this.__currentDefaultPath+=" ",this.__currentDefaultPath+=t}moveTo(t,r){this.__currentElement.nodeName!=="path"&&this.beginPath(),this.__currentPosition={x:t,y:r},this.__addPathCommand(Gr("M {x} {y}",{x:this.__matrixTransform(t,r).x,y:this.__matrixTransform(t,r).y}))}closePath(){this.__currentDefaultPath&&this.__addPathCommand("Z")}lineTo(t,r){this.__currentPosition={x:t,y:r},this.__currentDefaultPath.includes("M")?this.__addPathCommand(Gr("L {x} {y}",{x:this.__matrixTransform(t,r).x,y:this.__matrixTransform(t,r).y})):this.__addPathCommand(Gr("M {x} {y}",{x:this.__matrixTransform(t,r).x,y:this.__matrixTransform(t,r).y}))}bezierCurveTo(t,r,n,o,i,s){this.__currentPosition={x:i,y:s},this.__addPathCommand(Gr("C {cp1x} {cp1y} {cp2x} {cp2y} {x} {y}",{cp1x:this.__matrixTransform(t,r).x,cp1y:this.__matrixTransform(t,r).y,cp2x:this.__matrixTransform(n,o).x,cp2y:this.__matrixTransform(n,o).y,x:this.__matrixTransform(i,s).x,y:this.__matrixTransform(i,s).y}))}quadraticCurveTo(t,r,n,o){this.__currentPosition={x:n,y:o},this.__addPathCommand(Gr("Q {cpx} {cpy} {x} {y}",{cpx:this.__matrixTransform(t,r).x,cpy:this.__matrixTransform(t,r).y,x:this.__matrixTransform(n,o).x,y:this.__matrixTransform(n,o).y}))}stroke(){this.__currentElement.nodeName==="path"&&this.__currentElement.setAttribute("paint-order","fill stroke markers"),this.__applyCurrentDefaultPath(),this.__applyStyleToCurrentElement("stroke")}fill(){this.__currentElement.nodeName==="path"&&this.__currentElement.setAttribute("paint-order","stroke fill markers"),this.__applyCurrentDefaultPath(),this.__applyStyleToCurrentElement("fill")}rect(t,r,n,o){this.__currentElement.nodeName!=="path"&&this.beginPath(),this.moveTo(t,r),this.lineTo(t+n,r),this.lineTo(t+n,r+o),this.lineTo(t,r+o),this.lineTo(t,r),this.closePath()}__clearCanvas(){let t=this.__root.childNodes[1];this.__root.removeChild(t),this.__currentElement=this.__document.createElementNS("http://www.w3.org/2000/svg","g"),this.__root.appendChild(this.__currentElement),this.__groupStack=[]}fillRect(t,r,n,o){let{a:i,b:s,c:a,d:c,e:l,f:u}=this.getTransform();JSON.stringify([i,s,a,c,l,u])===JSON.stringify([1,0,0,1,0,0])&&t===0&&r===0&&n===this.width&&o===this.height&&this.__clearCanvas();let d=this.__createElement("rect",{x:t,y:r,width:n,height:o},!0);this.__closestGroupOrSvg().appendChild(d),this.__currentElement=d,this.__applyTransformation(d),this.__applyStyleToCurrentElement("fill")}strokeRect(t,r,n,o){let i=this.__createElement("rect",{x:t,y:r,width:n,height:o},!0);this.__closestGroupOrSvg().appendChild(i),this.__currentElement=i,this.__applyTransformation(i),this.__applyStyleToCurrentElement("stroke")}clearRect(t,r,n,o){let{a:i,b:s,c:a,d:c,e:l,f:u}=this.getTransform();if(JSON.stringify([i,s,a,c,l,u])===JSON.stringify([1,0,0,1,0,0])&&t===0&&r===0&&n===this.width&&o===this.height){this.__clearCanvas();return}let d=this.__createElement("rect",{x:t,y:r,width:n,height:o,fill:"#FFFFFF"},!0);this.__applyTransformation(d),this.__closestGroupOrSvg().appendChild(d)}createLinearGradient(t,r,n,o){let i=this.__createElement("linearGradient",{id:gg(this.__ids),x1:t+"px",x2:n+"px",y1:r+"px",y2:o+"px",gradientUnits:"userSpaceOnUse"});return this.__defs.appendChild(i),new Lc(i,this)}createRadialGradient(t,r,n,o,i,s){let a=this.__createElement("radialGradient",{id:gg(this.__ids),cx:o+"px",cy:i+"px",r:s+"px",fx:t+"px",fy:r+"px",gradientUnits:"userSpaceOnUse"});return this.__defs.appendChild(a),new Lc(a,this)}__applyText(t,r,n,o){let i=document.createElement("span");i.setAttribute("style","font:"+this.font);let s=i.style,a=this.__closestGroupOrSvg(),c=this.__createElement("text",{"font-family":s.fontFamily,"font-size":s.fontSize,"font-style":s.fontStyle,"font-weight":s.fontWeight,"text-decoration":this.__fontUnderline,x:r,y:n,"text-anchor":hG(this.textAlign),"dominant-baseline":yG(this.textBaseline)},!0);c.appendChild(this.__document.createTextNode(t)),this.__currentElement=c,this.__applyTransformation(c),this.__applyStyleToCurrentElement(o);let l=c;if(this.__fontHref){let u=this.__createElement("a");u.setAttributeNS("http://www.w3.org/1999/xlink","xlink:href",this.__fontHref),u.appendChild(c),l=u}a.appendChild(l)}fillText(t,r,n){this.__applyText(t,r,n,"fill")}strokeText(t,r,n){this.__applyText(t,r,n,"stroke")}measureText(t){return this.__ctx.font=this.font,this.__ctx.measureText(t)}arc(t,r,n,o,i,s){if(o===i)return;o=o%(2*Math.PI),i=i%(2*Math.PI),o===i&&(i=(i+2*Math.PI-.001*(s?-1:1))%(2*Math.PI));let a=t+n*Math.cos(i),c=r+n*Math.sin(i),l=t+n*Math.cos(o),u=r+n*Math.sin(o),d=s?0:1,A=0,f=i-o;f<0&&(f+=2*Math.PI),s?A=f>Math.PI?0:1:A=f>Math.PI?1:0;let g=Math.hypot(this.__transformMatrix.a,this.__transformMatrix.b),h=Math.hypot(this.__transformMatrix.c,this.__transformMatrix.d);this.lineTo(l,u),this.__addPathCommand(Gr("A {rx} {ry} {xAxisRotation} {largeArcFlag} {sweepFlag} {endX} {endY}",{rx:n*g,ry:n*h,xAxisRotation:0,largeArcFlag:A,sweepFlag:d,endX:this.__matrixTransform(a,c).x,endY:this.__matrixTransform(a,c).y})),this.__currentPosition={x:a,y:c}}clip(){let t=this.__closestGroupOrSvg(),r=this.__createElement("clipPath"),n=gg(this.__ids),o=this.__createElement("g");this.__applyCurrentDefaultPath(),t.removeChild(this.__currentElement),r.setAttribute("id",n),r.appendChild(this.__currentElement),this.__defs.appendChild(r),t.setAttribute("clip-path",Gr("url(#{id})",{id:n})),t.appendChild(o),this.__currentElement=o}setLineDash(t){t&&t.length>0?this.lineDash=t.join(","):this.lineDash=null}setTransform(t,r,n,o,i,s){t instanceof DOMMatrix?this.__transformMatrix=new DOMMatrix([t.a,t.b,t.c,t.d,t.e,t.f]):this.__transformMatrix=new DOMMatrix([t,r,n,o,i,s])}getTransform(){let{a:t,b:r,c:n,d:o,e:i,f:s}=this.__transformMatrix;return new DOMMatrix([t,r,n,o,i,s])}resetTransform(){this.setTransform(1,0,0,1,0,0)}scale(t,r){if(r===void 0&&(r=t),isNaN(t)||isNaN(r)||!isFinite(t)||!isFinite(r))return;let n=this.getTransform().scale(t,r);this.setTransform(n)}rotate(t){let r=this.getTransform().multiply(new DOMMatrix([Math.cos(t),Math.sin(t),-Math.sin(t),Math.cos(t),0,0]));this.setTransform(r)}translate(t,r){let n=this.getTransform().translate(t,r);this.setTransform(n)}transform(t,r,n,o,i,s){let a=this.getTransform().multiply(new DOMMatrix([t,r,n,o,i,s]));this.setTransform(a)}__matrixTransform(t,r){return new DOMPoint(t,r).matrixTransform(this.__transformMatrix)}__getTransformScale(){return{x:Math.hypot(this.__transformMatrix.a,this.__transformMatrix.b),y:Math.hypot(this.__transformMatrix.c,this.__transformMatrix.d)}}__getTransformRotation(){return Math.atan2(this.__transformMatrix.b,this.__transformMatrix.a)}drawFocusRing(){}createImageData(){}putImageData(){}globalCompositeOperation(){}drawImage(){}createPattern(){return null}}});var XI={};Bt(XI,{renderToSvg:()=>KI});function EG(e){let t=e.visibleDomainTypes.map(o=>o.name),r=Math.max(0,...t.map(o=>o.length)),n=Fc*2+Pc+6+r*CG;return Math.min(360,Math.max(120,n))}function bG(e,t){let{width:r,height:n,scrollX:o,scrollY:i,totalWidth:s,totalHeight:a,treeAreaWidth:c,totalTrackAreaHeight:l,minimapHeight:u}=e,d=t.includeTracks?l:0,A=t.exportType==="viewport"&&!!t.includeMinimap,f=e.actuallyShowDomains&&e.visibleDomainTypes.length>0?EG(e):0;return t.exportType==="entire"?{width:s+c,height:a+d,contentHeight:a,trackHeight:d,offsetX:0,offsetY:0,includeMinimap:A,legendWidth:f}:{width:r,height:n+(A?u:0)+d,contentHeight:n,trackHeight:d,offsetX:-o,offsetY:-i,includeMinimap:A,legendWidth:f}}async function KI(e,t){await(0,JI.when)(()=>e.dataInitialized);let{Context:r}=await Promise.resolve().then(()=>(YI(),WI));return(0,zI.renderToStaticMarkup)(ie.default.createElement(wG,{model:e,theme:t.theme,Context:r,layout:bG(e,t)}))}function wG({model:e,theme:t,Context:r,layout:n}){let{width:o,height:i,trackHeight:s,includeMinimap:a,legendWidth:c}=n,{treeAreaWidth:l,minimapHeight:u}=e,d=o+c,A=a?u:0,f=ie.default.createElement(ie.default.Fragment,null,s>0?ie.default.createElement(vG,{Context:r,model:e,theme:t,layout:n}):null,ie.default.createElement("g",{transform:s>0?`translate(0 ${s})`:void 0},ie.default.createElement(SG,{Context:r,model:e,theme:t,layout:n})));return ie.default.createElement("svg",{width:d,height:i,xmlns:"http://www.w3.org/2000/svg",xmlnsXlink:"http://www.w3.org/1999/xlink",viewBox:`0 0 ${d} ${i}`},ie.default.createElement("rect",{width:"100%",height:"100%",fill:"white"}),a?ie.default.createElement(ie.default.Fragment,null,ie.default.createElement("g",{transform:`translate(${l} 0)`},ie.default.createElement(oI,{model:e})),ie.default.createElement("g",{transform:`translate(0 ${u})`},f)):f,c>0?ie.default.createElement("g",{transform:`translate(${o} ${A})`},ie.default.createElement(IG,{model:e,width:c})):null)}function IG({model:e,width:t}){let{visibleDomainTypes:r,fillPalette:n,strokePalette:o}=e,i=Fc*2+r.length*qI;return ie.default.createElement("g",null,ie.default.createElement("rect",{x:0,y:0,width:t-4,height:i,fill:"white",stroke:"#ccc",rx:2}),r.map((s,a)=>{let c=Fc+a*qI;return ie.default.createElement("g",{key:s.accession},ie.default.createElement("rect",{x:Fc,y:c,width:Pc,height:Pc,fill:n[s.accession],stroke:o[s.accession]}),ie.default.createElement("text",{x:Fc+Pc+6,y:c+Pc-1,fontSize:xG},s.name))}))}function SG({model:e,theme:t,layout:r,Context:n}){let{contentHeight:o,offsetX:i,offsetY:s,width:a}=r,{treeAreaWidth:c,colorScheme:l,id:u}=e,d=a-c,A=Rc(l,t),f=new n(c,o);Sf({model:e,theme:t,ctx:f,offsetY:s,blockSizeYOverride:o,highResScaleFactorOverride:1});let g=new n(d,o);return Af({model:e,ctx:g,offsetX:i,offsetY:s,blockSizeYOverride:o,highResScaleFactorOverride:1}),yf({model:e,theme:t,ctx:g,contrastScheme:A,offsetX:i,offsetY:s,blockSizeXOverride:d,blockSizeYOverride:o,highResScaleFactorOverride:1}),ie.default.createElement(ie.default.Fragment,null,ie.default.createElement(xg,{clipId:`tree-${u}`,width:c,height:o,ctx:f}),ie.default.createElement(xg,{clipId:`msa-${u}`,width:d,height:o,transform:`translate(${c} 0)`,ctx:g}))}function vG({model:e,theme:t,layout:r,Context:n}){let{trackHeight:o,offsetX:i,width:s}=r,{treeAreaWidth:a,colorScheme:c,id:l}=e,u=s-a,d=Rc(c,t),A=new n(u,o);return kI({model:e,ctx:A,contrastScheme:d,theme:t,offsetX:i,blockSizeXOverride:u,highResScaleFactorOverride:1}),ie.default.createElement("g",{transform:`translate(${a} 0)`},ie.default.createElement(xg,{clipId:`tracks-${l}`,width:u,height:o,ctx:A}))}function xg({clipId:e,width:t,height:r,transform:n,ctx:o}){return ie.default.createElement(ie.default.Fragment,null,ie.default.createElement("defs",null,ie.default.createElement("clipPath",{id:e},ie.default.createElement("rect",{x:0,y:0,width:t,height:r}))),ie.default.createElement("g",{clipPath:`url(#${e})`,transform:n,dangerouslySetInnerHTML:{__html:o.getSvg().innerHTML}}))}var ie,zI,JI,Fc,qI,Pc,xG,CG,Cg=m(()=>{ie=p(Q(),1),zI=p(be(),1),JI=p(Ls(),1);iI();qp();sg();xf();vf();ho();Fc=8,qI=16,Pc=12,xG=12,CG=7});var Xe=X((pte,ZI)=>{ZI.exports=JBrowseExports["@jbrowse/core/ui"]});var eS,tS,Hs,Eg=m(()=>{eS=p(O(),1),tS=p(Q(),1),Hs=class extends tS.Component{constructor(t){super(t),this.state={error:void 0}}componentDidCatch(t,r){console.error("ErrorBoundary caught an error:",t,r),this.setState({error:t})}render(){return this.state.error?(0,eS.jsx)(this.props.FallbackComponent,{error:this.state.error}):this.props.children}}});var U=X((hte,rS)=>{rS.exports=JBrowseExports["@mui/material"]});function yo(e,t){let r=(0,Vs.useRef)(!1),[n,o]=(0,Vs.useState)();return(0,Vs.useEffect)(()=>{if(n!==void 0){let a=function(l){r.current||(r.current=!0,requestAnimationFrame(()=>{let u=e==="x"?l.clientX:l.clientY;t(u-i,s),r.current=!1}))},c=function(){o(void 0)},{client:i,startScroll:s}=n;return document.addEventListener("mousemove",a),document.addEventListener("mouseup",c),()=>{document.removeEventListener("mousemove",a),document.removeEventListener("mouseup",c)}}},[e,t,n]),{dragging:n!==void 0,startDrag:(i,s)=>{o({client:e==="x"?i.clientX:i.clientY,startScroll:s})}}}var Vs,Bf=m(()=>{Vs=p(Q(),1)});var br,Tf,bg,wg,nS,oS,iS,Ig=m(()=>{br=p(Q(),1),Tf=p(Y(),1);Bf();bg="rgba(200,200,200)",wg="rgba(150,150,150)",nS=(0,Tf.observer)(function({model:e}){let{resizeHandleWidth:t}=e,[r,n]=(0,br.useState)(!1),{startDrag:o}=yo("x",(0,br.useCallback)((i,s)=>{e.setTreeAreaWidth(s+i)},[e]));return br.default.createElement("div",{onMouseDown:i=>{o(i,e.treeAreaWidth)},onMouseEnter:()=>{n(!0)},onMouseLeave:()=>{n(!1)},style:{cursor:"ew-resize",width:t,background:r?wg:bg,position:"relative"}})}),oS=(0,Tf.observer)(function({model:e}){let{resizeHandleWidth:t}=e,[r,n]=(0,br.useState)(!1),{startDrag:o}=yo("y",(0,br.useCallback)((i,s)=>{e.setHeight(s+i)},[e]));return br.default.createElement("div",{onMouseDown:i=>{o(i,e.height)},onMouseEnter:()=>{n(!0)},onMouseLeave:()=>{n(!1)},style:{cursor:"ns-resize",width:"100%",height:t,background:r?wg:bg,position:"relative"}})}),iS=(0,Tf.observer)(function({model:e}){let{resizeHandleWidth:t}=e,[r,n]=(0,br.useState)(!1),{startDrag:o}=yo("y",(0,br.useCallback)((i,s)=>{e.setConservationTrackHeight(Math.max(10,s+i))},[e]));return br.default.createElement("div",{onMouseDown:i=>{o(i,e.conservationTrackHeight)},onMouseEnter:()=>{n(!0)},onMouseLeave:()=>{n(!1)},style:{position:"absolute",bottom:0,left:0,cursor:"ns-resize",width:"100%",height:t,zIndex:1,background:r?wg:bg}})})});var Sg=X((Ete,sS)=>{sS.exports=JBrowseExports["@mui/material/styles"]});var js,vg=m(()=>{js=e=>{let t=e.length,r=0,n="";for(;r<t;r++){let o=e[r];if(o==null)continue;let i;switch(typeof o){case"boolean":break;case"object":{if(Array.isArray(o))i=js(o);else{let s=o;i="";for(let a in s)s[a]&&a&&(i&&(i+=" "),i+=a)}break}default:i=o}i&&(n&&(n+=" "),n+=i)}return n}});function aS(e){return e instanceof Object&&!("styles"in e)&&!("length"in e)&&!("__emotion_styles"in e)}var cS=m(()=>{});function fS(e){let{useCache:t}=e;function r(){let n=t(),{css:o,cx:i}=(0,uS.useMemo)(()=>BG({cache:n}),[n]);return{css:o,cx:i}}return{useCssAndCx:r}}var uS,BG,lS,dS=m(()=>{uS=p(Q(),1);ri();vs();vg();cS();({createCssAndCx:BG}=(()=>{function e(r,n,o){let i=[],s=ei(r,i,o);return i.length<2?o:s+n(i)}function t(r){let{cache:n}=r,o=(...s)=>{let a=fn(s,n.registered);ti(n,a,!1);let c=`${n.key}-${a.name}`;e:{let l=s[0];if(!aS(l))break e;lS.saveClassNameCSSObjectMapping(n,c,l)}return c};return{css:o,cx:(...s)=>{let a=js(s),c=lS.fixClassName(n,a,o);return e(n.registered,o,c)}}}return{createCssAndCx:t}})());lS=(()=>{let e=new WeakMap;return{saveClassNameCSSObjectMapping:(t,r,n)=>{let o=e.get(t);o===void 0&&(o=new Map,e.set(t,o)),o.set(r,n)},fixClassName:(()=>{function t(r){let n=!1;return r.map(([o,i])=>{if(i===void 0)return o;let s;if(n)s={"&&":i};else{s=o;for(let a in i)if(a.startsWith("@media")){n=!0;break}}return s})}return(r,n,o)=>{if(!n.includes(" "))return n;let i=e.get(r);return js(t(n.split(" ").map(s=>[s,i?.get(s)])).map(s=>typeof s=="string"?s:o(s)))}})()}})()});function AS(e,t,r){if(!(t instanceof Object))return e;let n=Object.keys(t);if(n.length===0)return e;let o={};for(let i of Object.keys(e))o[i]=r(e[i],t[i]);for(let i of n){if(i in e)continue;let s=t[i];typeof s=="string"&&(o[i]=s)}return o}var mS=m(()=>{});function pS(e){if(!(e instanceof Object)||typeof e=="function")return e;let t=[];for(let r in e){let n=e[r],o=typeof n;if(!(o==="string"||o==="number"&&!isNaN(n)||o==="boolean"||n===void 0||n===null))return e;t.push(`${r}:${o}_${n}`)}return`xSqLiJdLMd9s${t.join("|")}`}var gS=m(()=>{});function hS(e){let{useTheme:t}=e,{useCssAndCx:r}=fS({useCache:TG});function n(){return function(o){let i=typeof o=="function"?o:()=>o;return function(a,c){let l=t(),{css:u,cx:d}=r(),A=(0,Bg.useMemo)(()=>{let x=i(l),w={};for(let y of Object.keys(x)){let v=x[y];w[y]=u(v)}return w},[u,l]),f=c?.props.classes,g=pS(f);return{classes:(0,Bg.useMemo)(()=>f?AS(A,f,d):A,[A,g,d]),theme:l,css:u,cx:d}}}}return{makeStyles:n}}var Bg,TG,yS=m(()=>{"use client";Bg=p(Q(),1);gc();dS();mS();gS();TG=Jm});var xS,Z,CS=m(()=>{xS=p(Sg(),1);yS();({makeStyles:Z}=hS({useTheme:xS.useTheme}))});var ES=m(()=>{CS()});function Mf(...e){return js(e)}var He=m(()=>{"use client";gc();ES();vg()});var bS,wS,IS=m(()=>{"use client";we();bS=p(O(),1),wS=W((0,bS.jsx)("path",{d:"m7 10 5 5 5-5z"}),"ArrowDropDown")});function SS(e,t){return t===1?e*16:t===2?e*100:e}function vS(e){let t=Math.abs(e);return t<6?25:t>150?500:t>30?150:75}function BS(e,t){let r=MG*t,n=Math.max(-r,Math.min(r,e));return n>0?1/(1+n):1-n}var MG,TS=m(()=>{MG=.011997600479904018});function $s({ref:e,onScrollX:t,onScrollY:r,onZoom:n,scrollZoom:o}){let i=(0,Tt.useRef)(!1),s=(0,Tt.useRef)(!1),a=(0,Tt.useRef)(0),c=(0,Tt.useRef)(0),l=(0,Tt.useRef)(0),u=(0,Tt.useRef)(0),d=(0,Tt.useRef)(0),A=(0,Tt.useRef)(null),f=(0,Tt.useRef)(0),g=(0,Tt.useRef)(0),[h,x]=(0,Tt.useState)(!1);(0,Tt.useEffect)(()=>{let v=e.current;if(!v)return;function b(I){let S=I.ctrlKey||I.metaKey,B=o&&!I.shiftKey&&Math.abs(I.deltaY)>=Math.abs(I.deltaX);if(n&&(S||B)){let L=v.getBoundingClientRect(),P=SS(I.deltaY,I.deltaMode),C=S?vS(P):500;l.current+=P/C,u.current=I.clientX-L.left,d.current=I.clientY-L.top,s.current||(s.current=!0,requestAnimationFrame(M=>{let k=A.current===null?16.67:M-A.current;A.current=M,n(BS(l.current,Math.min(100,k)),u.current,d.current),l.current=0,s.current=!1})),I.preventDefault(),I.stopPropagation();return}let R=!!t&&I.deltaX!==0,D=!!r&&I.deltaY!==0;(R||D)&&(t&&(a.current+=I.deltaX),r&&(c.current+=I.deltaY),i.current||(i.current=!0,requestAnimationFrame(()=>{t&&(t(-a.current),a.current=0),r&&(r(-c.current),c.current=0),i.current=!1})),I.preventDefault(),I.stopPropagation())}return v.addEventListener("wheel",b,{passive:!1}),()=>{v.removeEventListener("wheel",b)}},[e,t,r,n,o]),(0,Tt.useEffect)(()=>{if(!h)return;function v(I){I.preventDefault();let S=I.clientX-f.current,B=I.clientY-g.current;(S&&t||B&&r)&&(i.current||(i.current=!0,requestAnimationFrame(()=>{t?.(S),r?.(B),i.current=!1,f.current=I.clientX,g.current=I.clientY})))}function b(){f.current=0,g.current=0,x(!1)}return window.addEventListener("mousemove",v,!0),window.addEventListener("mouseup",b,!0),()=>{window.removeEventListener("mousemove",v,!0),window.removeEventListener("mouseup",b,!0)}},[h,t,r]);function w(v){let b=v.target;b.draggable||b.dataset.resizer||v.button===0&&(f.current=v.clientX,g.current=v.clientY,x(!0))}function y(v){v.preventDefault(),x(!1)}return{onMouseDown:w,onMouseUp:y}}var Tt,Rf=m(()=>{Tt=p(Q(),1);TS()});function Oc(e){let t=navigator.clipboard;if(t?.writeText){t.writeText(e).catch(n=>{console.error("Failed to copy to clipboard:",n)});return}let r=document.createElement("textarea");r.value=e,r.style.position="fixed",r.style.opacity="0",document.body.append(r),r.select(),document.execCommand("copy"),r.remove()}var Tg=m(()=>{});var QS={};Bt(QS,{default:()=>kG});var Vn,MS,pi,RS,QG,_G,kG,_S=m(()=>{Vn=p(Q(),1),MS=p(Xe(),1);He();pi=p(U(),1),RS=p(Y(),1);Tg();QG=Z()(e=>({textArea:{padding:e.spacing(2),overflow:"auto",background:"#ddd",wordBreak:"break-word"}})),_G=(0,RS.observer)(function({model:e,onClose:t}){let[r,n]=(0,Vn.useState)("Copy to clipboard"),{classes:o}=QG();return Vn.default.createElement(MS.Dialog,{open:!0,onClose:t,fullWidth:!0,maxWidth:"lg",title:`Track info - ${e.name}`},Vn.default.createElement(pi.DialogContent,null,Vn.default.createElement(pi.Button,{variant:"contained",color:"primary",onClick:()=>{Oc(e.data),n("Copied!"),setTimeout(()=>{n("Copy to clipboard")},300)}},r),Vn.default.createElement("pre",{className:o.textArea},e.data)),Vn.default.createElement(pi.DialogActions,null,Vn.default.createElement(pi.Button,{variant:"contained",onClick:t,color:"secondary"},"Close")))}),kG=_G});var Ze,gi,Mg,DG,NG,LG,FG,kS,DS=m(()=>{Ze=p(Q(),1);He();IS();gi=p(U(),1),Mg=p(Y(),1);Rf();DG=(0,Ze.lazy)(()=>Promise.resolve().then(()=>(_S(),QS))),NG=Z()({button:{padding:0}}),LG=(0,Mg.observer)(function({model:t,track:r}){let[n,o]=(0,Ze.useState)(),i=()=>{o(void 0)},{drawLabels:s,fontSize:a,treeAreaWidth:c}=t,{model:{name:l,height:u}}=r,{classes:d}=NG(),A=Math.min(u,a);return Ze.default.createElement("div",{style:{width:c,height:u,flexShrink:0,textAlign:"right",fontSize:A}},s?l:""," ",Ze.default.createElement(gi.IconButton,{className:d.button,style:{width:A,height:A},onClick:f=>{o(f.currentTarget)}},Ze.default.createElement(wS,null)),n?Ze.default.createElement(gi.Menu,{anchorEl:n,transitionDuration:0,open:!0,onClose:()=>{i()}},Ze.default.createElement(gi.MenuItem,{dense:!0,onClick:()=>{t.toggleTrack(r.model.id),i()}},"Close"),Ze.default.createElement(gi.MenuItem,{dense:!0,onClick:()=>{t.queueDialog(f=>[DG,{onClose:f,model:r.model}]),i()}},"Get info")):null)}),FG=(0,Mg.observer)(function({model:e,track:t}){let{resizeHandleWidth:r,colWidth:n,scrollX:o,numColumns:i}=e,{model:{height:s}}=t,a=(0,Ze.useRef)(null),c=(0,Ze.useCallback)(l=>{e.doScrollX(l)},[e]);return $s({ref:a,onScrollX:c}),Ze.default.createElement("div",{style:{display:"flex",height:s}},Ze.default.createElement(LG,{model:e,track:t}),Ze.default.createElement("div",{style:{width:r,flexShrink:0}}),Ze.default.createElement("div",{ref:a,onMouseMove:l=>{if(!a.current)return;let{left:u}=a.current.getBoundingClientRect(),d=l.clientX-u-o,A=Math.floor(d/n);A>=0&&A<i?e.setMousePos(A,void 0):e.setMousePos(void 0,void 0)},onMouseLeave:()=>{e.setMousePos(void 0,void 0)}},Ze.default.createElement(t.ReactComponent,{model:e,track:t})))}),kS=FG});var hi,NS,LS,PG,FS,PS=m(()=>{hi=p(Q(),1),NS=p(be(),1),LS=p(Y(),1);Bf();PG=(0,LS.observer)(({model:e})=>{let{msaAreaHeight:t,scrollY:r,totalHeight:n}=e,[o,i]=(0,hi.useState)(!1),s="rgba(66, 119, 127, 0.3)",a=t/n,c=-r,l=c+t,u=c*a,d=l*a,{startDrag:A}=yo("y",(0,hi.useCallback)((f,g)=>{e.setScrollY((0,NS.clamp)(g-f/a,e.maxScrollY,0))},[e,a]));return hi.default.createElement("div",{style:{position:"relative",width:20,height:t,borderLeft:"1px solid #555",borderTop:"1px solid #555",boxSizing:"border-box"}},hi.default.createElement("div",{style:{position:"absolute",top:Math.max(0,u),left:0,background:o?"rgba(66,119,127,0.6)":s,cursor:"pointer",boxSizing:"border-box",width:20,height:Math.max(d-u,20),zIndex:100},onMouseOver:()=>{i(!0)},onMouseOut:()=>{i(!1)},onMouseDown:f=>{A(f,e.scrollY)}}))}),FS=PG});function Rg(){let e=(0,Ws.useRef)(null),[t,r]=(0,Ws.useState)({width:void 0,height:void 0});return(0,Ws.useEffect)(()=>{if(!e.current)return;let n=typeof window<"u"&&"ResizeObserver"in window?window.ResizeObserver:void 0;if(!n)return;let o=new n(i=>{r({width:i[0].contentRect.width,height:i[0].contentRect.height})});return o.observe(e.current),()=>{o.disconnect()}},[]),[e,t]}var Ws,OS=m(()=>{Ws=p(Q(),1)});var GS,US,HS=m(()=>{"use client";we();GS=p(O(),1),US=W((0,GS.jsx)("path",{d:"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m1 17h-2v-2h2zm2.07-7.75-.9.92C13.45 12.9 13 13.5 13 15h-2v-.5c0-1.1.45-2.1 1.17-2.83l1.24-1.26c.37-.36.59-.86.59-1.41 0-1.1-.9-2-2-2s-2 .9-2 2H8c0-2.21 1.79-4 4-4s4 1.79 4 4c0 .88-.36 1.68-.93 2.25"}),"Help")});var jS=X((are,VS)=>{VS.exports=JBrowseExports["@mui/material/utils"]});var Te,or=m(()=>{"use client";Te=p(jS(),1)});var $S,WS,YS=m(()=>{"use client";or();$S=p(O(),1),WS=(0,Te.createSvgIcon)((0,$S.jsx)("path",{d:"M10 6 8.59 7.41 13.17 12l-4.58 4.59L10 18l6-6z"}),"ChevronRight")});var qS,zS,JS=m(()=>{"use client";or();qS=p(O(),1),zS=(0,Te.createSvgIcon)((0,qS.jsx)("path",{d:"M11 18h2v-2h-2zm1-16C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m0 18c-4.41 0-8-3.59-8-8s3.59-8 8-8 8 3.59 8 8-3.59 8-8 8m0-14c-2.21 0-4 1.79-4 4h2c0-1.1.9-2 2-2s2 .9 2 2c0 2-3 1.75-3 5h2c0-2.25 3-2.5 3-5 0-2.21-1.79-4-4-4"}),"HelpOutline")});var KS,Qf,Qg=m(()=>{"use client";or();KS=p(O(),1),Qf=(0,Te.createSvgIcon)((0,KS.jsx)("path",{d:"M19 6.41 17.59 5 12 10.59 6.41 5 5 6.41 10.59 12 5 17.59 6.41 19 12 13.41 17.59 19 19 17.59 13.41 12z"}),"Close")});var XS,ZS,ev=m(()=>{"use client";or();XS=p(O(),1),ZS=(0,Te.createSvgIcon)((0,XS.jsx)("path",{d:"M17.65 6.35C16.2 4.9 14.21 4 12 4c-4.42 0-7.99 3.58-7.99 8s3.57 8 7.99 8c3.73 0 6.84-2.55 7.73-6h-2.08c-.82 2.33-3.04 4-5.65 4-3.31 0-6-2.69-6-6s2.69-6 6-6c1.66 0 3.14.69 4.22 1.78L13 11h7V4z"}),"Refresh")});var tv,rv,nv=m(()=>{"use client";or();tv=p(O(),1),rv=(0,Te.createSvgIcon)((0,tv.jsx)("path",{d:"M15.73 3H8.27L3 8.27v7.46L8.27 21h7.46L21 15.73V8.27zM12 17.3c-.72 0-1.3-.58-1.3-1.3s.58-1.3 1.3-1.3 1.3.58 1.3 1.3-.58 1.3-1.3 1.3m1-4.3h-2V7h2z"}),"Report")});function _g({children:e}){let{classes:t}=OG();return(0,ov.jsx)("div",{className:t.bg,children:e})}var ov,OG,iv=m(()=>{ov=p(O(),1);He();OG=Z()(e=>({bg:{padding:4,margin:4,overflow:"auto",maxHeight:200,background:e.palette.mode==="dark"?"#833":"#f88",border:`1px solid ${e.palette.divider}`}}))});var av=X(kg=>{var sv="ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/".split("");kg.encode=function(e){if(0<=e&&e<sv.length)return sv[e];throw new TypeError("Must be between 0 and 63: "+e)};kg.decode=function(e){var t=65,r=90,n=97,o=122,i=48,s=57,a=43,c=47,l=26,u=52;return t<=e&&e<=r?e-t:n<=e&&e<=o?e-n+l:i<=e&&e<=s?e-i+u:e==a?62:e==c?63:-1}});var Lg=X(Ng=>{var cv=av(),Dg=5,lv=1<<Dg,uv=lv-1,fv=lv;function GG(e){return e<0?(-e<<1)+1:(e<<1)+0}function UG(e){var t=(e&1)===1,r=e>>1;return t?-r:r}Ng.encode=function(t){var r="",n,o=GG(t);do n=o&uv,o>>>=Dg,o>0&&(n|=fv),r+=cv.encode(n);while(o>0);return r};Ng.decode=function(t,r,n){var o=t.length,i=0,s=0,a,c;do{if(r>=o)throw new Error("Expected more digits in base 64 VLQ value.");if(c=cv.decode(t.charCodeAt(r++)),c===-1)throw new Error("Invalid base64 digit: "+t.charAt(r-1));a=!!(c&fv),c&=uv,i=i+(c<<s),s+=Dg}while(a);n.value=UG(i),n.rest=r}});var qs=X(ut=>{function HG(e,t,r){if(t in e)return e[t];if(arguments.length===3)return r;throw new Error('"'+t+'" is a required argument.')}ut.getArg=HG;var dv=/^(?:([\w+\-.]+):)?\/\/(?:(\w+:\w+)@)?([\w.-]*)(?::(\d+))?(.*)$/,VG=/^data:.+\,.+$/;function Gc(e){var t=e.match(dv);return t?{scheme:t[1],auth:t[2],host:t[3],port:t[4],path:t[5]}:null}ut.urlParse=Gc;function Ys(e){var t="";return e.scheme&&(t+=e.scheme+":"),t+="//",e.auth&&(t+=e.auth+"@"),e.host&&(t+=e.host),e.port&&(t+=":"+e.port),e.path&&(t+=e.path),t}ut.urlGenerate=Ys;var jG=32;function $G(e){var t=[];return function(r){for(var n=0;n<t.length;n++)if(t[n].input===r){var o=t[0];return t[0]=t[n],t[n]=o,t[0].result}var i=e(r);return t.unshift({input:r,result:i}),t.length>jG&&t.pop(),i}}var Fg=$G(function(t){var r=t,n=Gc(t);if(n){if(!n.path)return t;r=n.path}for(var o=ut.isAbsolute(r),i=[],s=0,a=0;;)if(s=a,a=r.indexOf("/",s),a===-1){i.push(r.slice(s));break}else for(i.push(r.slice(s,a));a<r.length&&r[a]==="/";)a++;for(var c,l=0,a=i.length-1;a>=0;a--)c=i[a],c==="."?i.splice(a,1):c===".."?l++:l>0&&(c===""?(i.splice(a+1,l),l=0):(i.splice(a,2),l--));return r=i.join("/"),r===""&&(r=o?"/":"."),n?(n.path=r,Ys(n)):r});ut.normalize=Fg;function Av(e,t){e===""&&(e="."),t===""&&(t=".");var r=Gc(t),n=Gc(e);if(n&&(e=n.path||"/"),r&&!r.scheme)return n&&(r.scheme=n.scheme),Ys(r);if(r||t.match(VG))return t;if(n&&!n.host&&!n.path)return n.host=t,Ys(n);var o=t.charAt(0)==="/"?t:Fg(e.replace(/\/+$/,"")+"/"+t);return n?(n.path=o,Ys(n)):o}ut.join=Av;ut.isAbsolute=function(e){return e.charAt(0)==="/"||dv.test(e)};function WG(e,t){e===""&&(e="."),e=e.replace(/\/$/,"");for(var r=0;t.indexOf(e+"/")!==0;){var n=e.lastIndexOf("/");if(n<0||(e=e.slice(0,n),e.match(/^([^\/]+:\/)?\/*$/)))return t;++r}return Array(r+1).join("../")+t.substr(e.length+1)}ut.relative=WG;var mv=(function(){var e=Object.create(null);return!("__proto__"in e)})();function pv(e){return e}function YG(e){return gv(e)?"$"+e:e}ut.toSetString=mv?pv:YG;function qG(e){return gv(e)?e.slice(1):e}ut.fromSetString=mv?pv:qG;function gv(e){if(!e)return!1;var t=e.length;if(t<9||e.charCodeAt(t-1)!==95||e.charCodeAt(t-2)!==95||e.charCodeAt(t-3)!==111||e.charCodeAt(t-4)!==116||e.charCodeAt(t-5)!==111||e.charCodeAt(t-6)!==114||e.charCodeAt(t-7)!==112||e.charCodeAt(t-8)!==95||e.charCodeAt(t-9)!==95)return!1;for(var r=t-10;r>=0;r--)if(e.charCodeAt(r)!==36)return!1;return!0}function zG(e,t,r){var n=jn(e.source,t.source);return n!==0||(n=e.originalLine-t.originalLine,n!==0)||(n=e.originalColumn-t.originalColumn,n!==0||r)||(n=e.generatedColumn-t.generatedColumn,n!==0)||(n=e.generatedLine-t.generatedLine,n!==0)?n:jn(e.name,t.name)}ut.compareByOriginalPositions=zG;function JG(e,t,r){var n;return n=e.originalLine-t.originalLine,n!==0||(n=e.originalColumn-t.originalColumn,n!==0||r)||(n=e.generatedColumn-t.generatedColumn,n!==0)||(n=e.generatedLine-t.generatedLine,n!==0)?n:jn(e.name,t.name)}ut.compareByOriginalPositionsNoSource=JG;function KG(e,t,r){var n=e.generatedLine-t.generatedLine;return n!==0||(n=e.generatedColumn-t.generatedColumn,n!==0||r)||(n=jn(e.source,t.source),n!==0)||(n=e.originalLine-t.originalLine,n!==0)||(n=e.originalColumn-t.originalColumn,n!==0)?n:jn(e.name,t.name)}ut.compareByGeneratedPositionsDeflated=KG;function XG(e,t,r){var n=e.generatedColumn-t.generatedColumn;return n!==0||r||(n=jn(e.source,t.source),n!==0)||(n=e.originalLine-t.originalLine,n!==0)||(n=e.originalColumn-t.originalColumn,n!==0)?n:jn(e.name,t.name)}ut.compareByGeneratedPositionsDeflatedNoLine=XG;function jn(e,t){return e===t?0:e===null?1:t===null?-1:e>t?1:-1}function ZG(e,t){var r=e.generatedLine-t.generatedLine;return r!==0||(r=e.generatedColumn-t.generatedColumn,r!==0)||(r=jn(e.source,t.source),r!==0)||(r=e.originalLine-t.originalLine,r!==0)||(r=e.originalColumn-t.originalColumn,r!==0)?r:jn(e.name,t.name)}ut.compareByGeneratedPositionsInflated=ZG;function e8(e){return JSON.parse(e.replace(/^\)]}'[^\n]*\n/,""))}ut.parseSourceMapInput=e8;function t8(e,t,r){if(t=t||"",e&&(e[e.length-1]!=="/"&&t[0]!=="/"&&(e+="/"),t=e+t),r){var n=Gc(r);if(!n)throw new Error("sourceMapURL could not be parsed");if(n.path){var o=n.path.lastIndexOf("/");o>=0&&(n.path=n.path.substring(0,o+1))}t=Av(Ys(n),t)}return Fg(t)}ut.computeSourceURL=t8});var Gg=X(hv=>{var Pg=qs(),Og=Object.prototype.hasOwnProperty,yi=typeof Map<"u";function $n(){this._array=[],this._set=yi?new Map:Object.create(null)}$n.fromArray=function(t,r){for(var n=new $n,o=0,i=t.length;o<i;o++)n.add(t[o],r);return n};$n.prototype.size=function(){return yi?this._set.size:Object.getOwnPropertyNames(this._set).length};$n.prototype.add=function(t,r){var n=yi?t:Pg.toSetString(t),o=yi?this.has(t):Og.call(this._set,n),i=this._array.length;(!o||r)&&this._array.push(t),o||(yi?this._set.set(t,i):this._set[n]=i)};$n.prototype.has=function(t){if(yi)return this._set.has(t);var r=Pg.toSetString(t);return Og.call(this._set,r)};$n.prototype.indexOf=function(t){if(yi){var r=this._set.get(t);if(r>=0)return r}else{var n=Pg.toSetString(t);if(Og.call(this._set,n))return this._set[n]}throw new Error('"'+t+'" is not in the set.')};$n.prototype.at=function(t){if(t>=0&&t<this._array.length)return this._array[t];throw new Error("No element indexed by "+t)};$n.prototype.toArray=function(){return this._array.slice()};hv.ArraySet=$n});var Cv=X(xv=>{var yv=qs();function r8(e,t){var r=e.generatedLine,n=t.generatedLine,o=e.generatedColumn,i=t.generatedColumn;return n>r||n==r&&i>=o||yv.compareByGeneratedPositionsInflated(e,t)<=0}function _f(){this._array=[],this._sorted=!0,this._last={generatedLine:-1,generatedColumn:0}}_f.prototype.unsortedForEach=function(t,r){this._array.forEach(t,r)};_f.prototype.add=function(t){r8(this._last,t)?(this._last=t,this._array.push(t)):(this._sorted=!1,this._array.push(t))};_f.prototype.toArray=function(){return this._sorted||(this._array.sort(yv.compareByGeneratedPositionsInflated),this._sorted=!0),this._array};xv.MappingList=_f});var Ug=X(Ev=>{var Uc=Lg(),qe=qs(),kf=Gg().ArraySet,n8=Cv().MappingList;function wr(e){e||(e={}),this._file=qe.getArg(e,"file",null),this._sourceRoot=qe.getArg(e,"sourceRoot",null),this._skipValidation=qe.getArg(e,"skipValidation",!1),this._ignoreInvalidMapping=qe.getArg(e,"ignoreInvalidMapping",!1),this._sources=new kf,this._names=new kf,this._mappings=new n8,this._sourcesContents=null}wr.prototype._version=3;wr.fromSourceMap=function(t,r){var n=t.sourceRoot,o=new wr(Object.assign(r||{},{file:t.file,sourceRoot:n}));return t.eachMapping(function(i){var s={generated:{line:i.generatedLine,column:i.generatedColumn}};i.source!=null&&(s.source=i.source,n!=null&&(s.source=qe.relative(n,s.source)),s.original={line:i.originalLine,column:i.originalColumn},i.name!=null&&(s.name=i.name)),o.addMapping(s)}),t.sources.forEach(function(i){var s=i;n!==null&&(s=qe.relative(n,i)),o._sources.has(s)||o._sources.add(s);var a=t.sourceContentFor(i);a!=null&&o.setSourceContent(i,a)}),o};wr.prototype.addMapping=function(t){var r=qe.getArg(t,"generated"),n=qe.getArg(t,"original",null),o=qe.getArg(t,"source",null),i=qe.getArg(t,"name",null);!this._skipValidation&&this._validateMapping(r,n,o,i)===!1||(o!=null&&(o=String(o),this._sources.has(o)||this._sources.add(o)),i!=null&&(i=String(i),this._names.has(i)||this._names.add(i)),this._mappings.add({generatedLine:r.line,generatedColumn:r.column,originalLine:n!=null&&n.line,originalColumn:n!=null&&n.column,source:o,name:i}))};wr.prototype.setSourceContent=function(t,r){var n=t;this._sourceRoot!=null&&(n=qe.relative(this._sourceRoot,n)),r!=null?(this._sourcesContents||(this._sourcesContents=Object.create(null)),this._sourcesContents[qe.toSetString(n)]=r):this._sourcesContents&&(delete this._sourcesContents[qe.toSetString(n)],Object.keys(this._sourcesContents).length===0&&(this._sourcesContents=null))};wr.prototype.applySourceMap=function(t,r,n){var o=r;if(r==null){if(t.file==null)throw new Error(`SourceMapGenerator.prototype.applySourceMap requires either an explicit source file, or the source map's "file" property. Both were omitted.`);o=t.file}var i=this._sourceRoot;i!=null&&(o=qe.relative(i,o));var s=new kf,a=new kf;this._mappings.unsortedForEach(function(c){if(c.source===o&&c.originalLine!=null){var l=t.originalPositionFor({line:c.originalLine,column:c.originalColumn});l.source!=null&&(c.source=l.source,n!=null&&(c.source=qe.join(n,c.source)),i!=null&&(c.source=qe.relative(i,c.source)),c.originalLine=l.line,c.originalColumn=l.column,l.name!=null&&(c.name=l.name))}var u=c.source;u!=null&&!s.has(u)&&s.add(u);var d=c.name;d!=null&&!a.has(d)&&a.add(d)},this),this._sources=s,this._names=a,t.sources.forEach(function(c){var l=t.sourceContentFor(c);l!=null&&(n!=null&&(c=qe.join(n,c)),i!=null&&(c=qe.relative(i,c)),this.setSourceContent(c,l))},this)};wr.prototype._validateMapping=function(t,r,n,o){if(r&&typeof r.line!="number"&&typeof r.column!="number"){var i="original.line and original.column are not numbers -- you probably meant to omit the original mapping entirely and only map the generated position. If so, pass null for the original mapping instead of an object with empty or null values.";if(this._ignoreInvalidMapping)return typeof console<"u"&&console.warn&&console.warn(i),!1;throw new Error(i)}if(!(t&&"line"in t&&"column"in t&&t.line>0&&t.column>=0&&!r&&!n&&!o)){if(t&&"line"in t&&"column"in t&&r&&"line"in r&&"column"in r&&t.line>0&&t.column>=0&&r.line>0&&r.column>=0&&n)return;var i="Invalid mapping: "+JSON.stringify({generated:t,source:n,original:r,name:o});if(this._ignoreInvalidMapping)return typeof console<"u"&&console.warn&&console.warn(i),!1;throw new Error(i)}};wr.prototype._serializeMappings=function(){for(var t=0,r=1,n=0,o=0,i=0,s=0,a="",c,l,u,d,A=this._mappings.toArray(),f=0,g=A.length;f<g;f++){if(l=A[f],c="",l.generatedLine!==r)for(t=0;l.generatedLine!==r;)c+=";",r++;else if(f>0){if(!qe.compareByGeneratedPositionsInflated(l,A[f-1]))continue;c+=","}c+=Uc.encode(l.generatedColumn-t),t=l.generatedColumn,l.source!=null&&(d=this._sources.indexOf(l.source),c+=Uc.encode(d-s),s=d,c+=Uc.encode(l.originalLine-1-o),o=l.originalLine-1,c+=Uc.encode(l.originalColumn-n),n=l.originalColumn,l.name!=null&&(u=this._names.indexOf(l.name),c+=Uc.encode(u-i),i=u)),a+=c}return a};wr.prototype._generateSourcesContent=function(t,r){return t.map(function(n){if(!this._sourcesContents)return null;r!=null&&(n=qe.relative(r,n));var o=qe.toSetString(n);return Object.prototype.hasOwnProperty.call(this._sourcesContents,o)?this._sourcesContents[o]:null},this)};wr.prototype.toJSON=function(){var t={version:this._version,sources:this._sources.toArray(),names:this._names.toArray(),mappings:this._serializeMappings()};return this._file!=null&&(t.file=this._file),this._sourceRoot!=null&&(t.sourceRoot=this._sourceRoot),this._sourcesContents&&(t.sourcesContent=this._generateSourcesContent(t.sources,t.sourceRoot)),t};wr.prototype.toString=function(){return JSON.stringify(this.toJSON())};Ev.SourceMapGenerator=wr});var bv=X(xi=>{xi.GREATEST_LOWER_BOUND=1;xi.LEAST_UPPER_BOUND=2;function Hg(e,t,r,n,o,i){var s=Math.floor((t-e)/2)+e,a=o(r,n[s],!0);return a===0?s:a>0?t-s>1?Hg(s,t,r,n,o,i):i==xi.LEAST_UPPER_BOUND?t<n.length?t:-1:s:s-e>1?Hg(e,s,r,n,o,i):i==xi.LEAST_UPPER_BOUND?s:e<0?-1:e}xi.search=function(t,r,n,o){if(r.length===0)return-1;var i=Hg(-1,r.length,t,r,n,o||xi.GREATEST_LOWER_BOUND);if(i<0)return-1;for(;i-1>=0&&n(r[i],r[i-1],!0)===0;)--i;return i}});var Sv=X(Iv=>{function o8(e){function t(o,i,s){var a=o[i];o[i]=o[s],o[s]=a}function r(o,i){return Math.round(o+Math.random()*(i-o))}function n(o,i,s,a){if(s<a){var c=r(s,a),l=s-1;t(o,c,a);for(var u=o[a],d=s;d<a;d++)i(o[d],u,!1)<=0&&(l+=1,t(o,l,d));t(o,l+1,d);var A=l+1;n(o,i,s,A-1),n(o,i,A+1,a)}}return n}function i8(e){let t=o8.toString();return new Function(`return ${t}`)()(e)}var wv=new WeakMap;Iv.quickSort=function(e,t,r=0){let n=wv.get(t);n===void 0&&(n=i8(t),wv.set(t,n)),n(e,t,r,e.length-1)}});var Tv=X(Df=>{var H=qs(),jg=bv(),zs=Gg().ArraySet,s8=Lg(),Hc=Sv().quickSort;function Me(e,t){var r=e;return typeof e=="string"&&(r=H.parseSourceMapInput(e)),r.sections!=null?new Ur(r,t):new xt(r,t)}Me.fromSourceMap=function(e,t){return xt.fromSourceMap(e,t)};Me.prototype._version=3;Me.prototype.__generatedMappings=null;Object.defineProperty(Me.prototype,"_generatedMappings",{configurable:!0,enumerable:!0,get:function(){return this.__generatedMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__generatedMappings}});Me.prototype.__originalMappings=null;Object.defineProperty(Me.prototype,"_originalMappings",{configurable:!0,enumerable:!0,get:function(){return this.__originalMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__originalMappings}});Me.prototype._charIsMappingSeparator=function(t,r){var n=t.charAt(r);return n===";"||n===","};Me.prototype._parseMappings=function(t,r){throw new Error("Subclasses must implement _parseMappings")};Me.GENERATED_ORDER=1;Me.ORIGINAL_ORDER=2;Me.GREATEST_LOWER_BOUND=1;Me.LEAST_UPPER_BOUND=2;Me.prototype.eachMapping=function(t,r,n){var o=r||null,i=n||Me.GENERATED_ORDER,s;switch(i){case Me.GENERATED_ORDER:s=this._generatedMappings;break;case Me.ORIGINAL_ORDER:s=this._originalMappings;break;default:throw new Error("Unknown order of iteration.")}for(var a=this.sourceRoot,c=t.bind(o),l=this._names,u=this._sources,d=this._sourceMapURL,A=0,f=s.length;A<f;A++){var g=s[A],h=g.source===null?null:u.at(g.source);h!==null&&(h=H.computeSourceURL(a,h,d)),c({source:h,generatedLine:g.generatedLine,generatedColumn:g.generatedColumn,originalLine:g.originalLine,originalColumn:g.originalColumn,name:g.name===null?null:l.at(g.name)})}};Me.prototype.allGeneratedPositionsFor=function(t){var r=H.getArg(t,"line"),n={source:H.getArg(t,"source"),originalLine:r,originalColumn:H.getArg(t,"column",0)};if(n.source=this._findSourceIndex(n.source),n.source<0)return[];var o=[],i=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",H.compareByOriginalPositions,jg.LEAST_UPPER_BOUND);if(i>=0){var s=this._originalMappings[i];if(t.column===void 0)for(var a=s.originalLine;s&&s.originalLine===a;)o.push({line:H.getArg(s,"generatedLine",null),column:H.getArg(s,"generatedColumn",null),lastColumn:H.getArg(s,"lastGeneratedColumn",null)}),s=this._originalMappings[++i];else for(var c=s.originalColumn;s&&s.originalLine===r&&s.originalColumn==c;)o.push({line:H.getArg(s,"generatedLine",null),column:H.getArg(s,"generatedColumn",null),lastColumn:H.getArg(s,"lastGeneratedColumn",null)}),s=this._originalMappings[++i]}return o};Df.SourceMapConsumer=Me;function xt(e,t){var r=e;typeof e=="string"&&(r=H.parseSourceMapInput(e));var n=H.getArg(r,"version"),o=H.getArg(r,"sources"),i=H.getArg(r,"names",[]),s=H.getArg(r,"sourceRoot",null),a=H.getArg(r,"sourcesContent",null),c=H.getArg(r,"mappings"),l=H.getArg(r,"file",null);if(n!=this._version)throw new Error("Unsupported version: "+n);s&&(s=H.normalize(s)),o=o.map(String).map(H.normalize).map(function(u){return s&&H.isAbsolute(s)&&H.isAbsolute(u)?H.relative(s,u):u}),this._names=zs.fromArray(i.map(String),!0),this._sources=zs.fromArray(o,!0),this._absoluteSources=this._sources.toArray().map(function(u){return H.computeSourceURL(s,u,t)}),this.sourceRoot=s,this.sourcesContent=a,this._mappings=c,this._sourceMapURL=t,this.file=l}xt.prototype=Object.create(Me.prototype);xt.prototype.consumer=Me;xt.prototype._findSourceIndex=function(e){var t=e;if(this.sourceRoot!=null&&(t=H.relative(this.sourceRoot,t)),this._sources.has(t))return this._sources.indexOf(t);var r;for(r=0;r<this._absoluteSources.length;++r)if(this._absoluteSources[r]==e)return r;return-1};xt.fromSourceMap=function(t,r){var n=Object.create(xt.prototype),o=n._names=zs.fromArray(t._names.toArray(),!0),i=n._sources=zs.fromArray(t._sources.toArray(),!0);n.sourceRoot=t._sourceRoot,n.sourcesContent=t._generateSourcesContent(n._sources.toArray(),n.sourceRoot),n.file=t._file,n._sourceMapURL=r,n._absoluteSources=n._sources.toArray().map(function(f){return H.computeSourceURL(n.sourceRoot,f,r)});for(var s=t._mappings.toArray().slice(),a=n.__generatedMappings=[],c=n.__originalMappings=[],l=0,u=s.length;l<u;l++){var d=s[l],A=new Bv;A.generatedLine=d.generatedLine,A.generatedColumn=d.generatedColumn,d.source&&(A.source=i.indexOf(d.source),A.originalLine=d.originalLine,A.originalColumn=d.originalColumn,d.name&&(A.name=o.indexOf(d.name)),c.push(A)),a.push(A)}return Hc(n.__originalMappings,H.compareByOriginalPositions),n};xt.prototype._version=3;Object.defineProperty(xt.prototype,"sources",{get:function(){return this._absoluteSources.slice()}});function Bv(){this.generatedLine=0,this.generatedColumn=0,this.source=null,this.originalLine=null,this.originalColumn=null,this.name=null}var Vg=H.compareByGeneratedPositionsDeflatedNoLine;function vv(e,t){let r=e.length,n=e.length-t;if(!(n<=1))if(n==2){let o=e[t],i=e[t+1];Vg(o,i)>0&&(e[t]=i,e[t+1]=o)}else if(n<20)for(let o=t;o<r;o++)for(let i=o;i>t;i--){let s=e[i-1],a=e[i];if(Vg(s,a)<=0)break;e[i-1]=a,e[i]=s}else Hc(e,Vg,t)}xt.prototype._parseMappings=function(t,r){var n=1,o=0,i=0,s=0,a=0,c=0,l=t.length,u=0,d={},A={},f=[],g=[],h,x,w,y,v;let b=0;for(;u<l;)if(t.charAt(u)===";")n++,u++,o=0,vv(g,b),b=g.length;else if(t.charAt(u)===",")u++;else{for(h=new Bv,h.generatedLine=n,y=u;y<l&&!this._charIsMappingSeparator(t,y);y++);for(x=t.slice(u,y),w=[];u<y;)s8.decode(t,u,A),v=A.value,u=A.rest,w.push(v);if(w.length===2)throw new Error("Found a source, but no line and column");if(w.length===3)throw new Error("Found a source and line, but no column");if(h.generatedColumn=o+w[0],o=h.generatedColumn,w.length>1&&(h.source=a+w[1],a+=w[1],h.originalLine=i+w[2],i=h.originalLine,h.originalLine+=1,h.originalColumn=s+w[3],s=h.originalColumn,w.length>4&&(h.name=c+w[4],c+=w[4])),g.push(h),typeof h.originalLine=="number"){let S=h.source;for(;f.length<=S;)f.push(null);f[S]===null&&(f[S]=[]),f[S].push(h)}}vv(g,b),this.__generatedMappings=g;for(var I=0;I<f.length;I++)f[I]!=null&&Hc(f[I],H.compareByOriginalPositionsNoSource);this.__originalMappings=[].concat(...f)};xt.prototype._findMapping=function(t,r,n,o,i,s){if(t[n]<=0)throw new TypeError("Line must be greater than or equal to 1, got "+t[n]);if(t[o]<0)throw new TypeError("Column must be greater than or equal to 0, got "+t[o]);return jg.search(t,r,i,s)};xt.prototype.computeColumnSpans=function(){for(var t=0;t<this._generatedMappings.length;++t){var r=this._generatedMappings[t];if(t+1<this._generatedMappings.length){var n=this._generatedMappings[t+1];if(r.generatedLine===n.generatedLine){r.lastGeneratedColumn=n.generatedColumn-1;continue}}r.lastGeneratedColumn=1/0}};xt.prototype.originalPositionFor=function(t){var r={generatedLine:H.getArg(t,"line"),generatedColumn:H.getArg(t,"column")},n=this._findMapping(r,this._generatedMappings,"generatedLine","generatedColumn",H.compareByGeneratedPositionsDeflated,H.getArg(t,"bias",Me.GREATEST_LOWER_BOUND));if(n>=0){var o=this._generatedMappings[n];if(o.generatedLine===r.generatedLine){var i=H.getArg(o,"source",null);i!==null&&(i=this._sources.at(i),i=H.computeSourceURL(this.sourceRoot,i,this._sourceMapURL));var s=H.getArg(o,"name",null);return s!==null&&(s=this._names.at(s)),{source:i,line:H.getArg(o,"originalLine",null),column:H.getArg(o,"originalColumn",null),name:s}}}return{source:null,line:null,column:null,name:null}};xt.prototype.hasContentsOfAllSources=function(){return this.sourcesContent?this.sourcesContent.length>=this._sources.size()&&!this.sourcesContent.some(function(t){return t==null}):!1};xt.prototype.sourceContentFor=function(t,r){if(!this.sourcesContent)return null;var n=this._findSourceIndex(t);if(n>=0)return this.sourcesContent[n];var o=t;this.sourceRoot!=null&&(o=H.relative(this.sourceRoot,o));var i;if(this.sourceRoot!=null&&(i=H.urlParse(this.sourceRoot))){var s=o.replace(/^file:\/\//,"");if(i.scheme=="file"&&this._sources.has(s))return this.sourcesContent[this._sources.indexOf(s)];if((!i.path||i.path=="/")&&this._sources.has("/"+o))return this.sourcesContent[this._sources.indexOf("/"+o)]}if(r)return null;throw new Error('"'+o+'" is not in the SourceMap.')};xt.prototype.generatedPositionFor=function(t){var r=H.getArg(t,"source");if(r=this._findSourceIndex(r),r<0)return{line:null,column:null,lastColumn:null};var n={source:r,originalLine:H.getArg(t,"line"),originalColumn:H.getArg(t,"column")},o=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",H.compareByOriginalPositions,H.getArg(t,"bias",Me.GREATEST_LOWER_BOUND));if(o>=0){var i=this._originalMappings[o];if(i.source===n.source)return{line:H.getArg(i,"generatedLine",null),column:H.getArg(i,"generatedColumn",null),lastColumn:H.getArg(i,"lastGeneratedColumn",null)}}return{line:null,column:null,lastColumn:null}};Df.BasicSourceMapConsumer=xt;function Ur(e,t){var r=e;typeof e=="string"&&(r=H.parseSourceMapInput(e));var n=H.getArg(r,"version"),o=H.getArg(r,"sections");if(n!=this._version)throw new Error("Unsupported version: "+n);this._sources=new zs,this._names=new zs;var i={line:-1,column:0};this._sections=o.map(function(s){if(s.url)throw new Error("Support for url field in sections not implemented.");var a=H.getArg(s,"offset"),c=H.getArg(a,"line"),l=H.getArg(a,"column");if(c<i.line||c===i.line&&l<i.column)throw new Error("Section offsets must be ordered and non-overlapping.");return i=a,{generatedOffset:{generatedLine:c+1,generatedColumn:l+1},consumer:new Me(H.getArg(s,"map"),t)}})}Ur.prototype=Object.create(Me.prototype);Ur.prototype.constructor=Me;Ur.prototype._version=3;Object.defineProperty(Ur.prototype,"sources",{get:function(){for(var e=[],t=0;t<this._sections.length;t++)for(var r=0;r<this._sections[t].consumer.sources.length;r++)e.push(this._sections[t].consumer.sources[r]);return e}});Ur.prototype.originalPositionFor=function(t){var r={generatedLine:H.getArg(t,"line"),generatedColumn:H.getArg(t,"column")},n=jg.search(r,this._sections,function(i,s){var a=i.generatedLine-s.generatedOffset.generatedLine;return a||i.generatedColumn-s.generatedOffset.generatedColumn}),o=this._sections[n];return o?o.consumer.originalPositionFor({line:r.generatedLine-(o.generatedOffset.generatedLine-1),column:r.generatedColumn-(o.generatedOffset.generatedLine===r.generatedLine?o.generatedOffset.generatedColumn-1:0),bias:t.bias}):{source:null,line:null,column:null,name:null}};Ur.prototype.hasContentsOfAllSources=function(){return this._sections.every(function(t){return t.consumer.hasContentsOfAllSources()})};Ur.prototype.sourceContentFor=function(t,r){for(var n=0;n<this._sections.length;n++){var o=this._sections[n],i=o.consumer.sourceContentFor(t,!0);if(i||i==="")return i}if(r)return null;throw new Error('"'+t+'" is not in the SourceMap.')};Ur.prototype.generatedPositionFor=function(t){for(var r=0;r<this._sections.length;r++){var n=this._sections[r];if(n.consumer._findSourceIndex(H.getArg(t,"source"))!==-1){var o=n.consumer.generatedPositionFor(t);if(o){var i={line:o.line+(n.generatedOffset.generatedLine-1),column:o.column+(n.generatedOffset.generatedLine===o.line?n.generatedOffset.generatedColumn-1:0)};return i}}}return{line:null,column:null}};Ur.prototype._parseMappings=function(t,r){this.__generatedMappings=[],this.__originalMappings=[];for(var n=0;n<this._sections.length;n++)for(var o=this._sections[n],i=o.consumer._generatedMappings,s=0;s<i.length;s++){var a=i[s],c=o.consumer._sources.at(a.source);c!==null&&(c=H.computeSourceURL(o.consumer.sourceRoot,c,this._sourceMapURL)),this._sources.add(c),c=this._sources.indexOf(c);var l=null;a.name&&(l=o.consumer._names.at(a.name),this._names.add(l),l=this._names.indexOf(l));var u={source:c,generatedLine:a.generatedLine+(o.generatedOffset.generatedLine-1),generatedColumn:a.generatedColumn+(o.generatedOffset.generatedLine===a.generatedLine?o.generatedOffset.generatedColumn-1:0),originalLine:a.originalLine,originalColumn:a.originalColumn,name:l};this.__generatedMappings.push(u),typeof u.originalLine=="number"&&this.__originalMappings.push(u)}Hc(this.__generatedMappings,H.compareByGeneratedPositionsDeflated),Hc(this.__originalMappings,H.compareByOriginalPositions)};Df.IndexedSourceMapConsumer=Ur});var Rv=X(Mv=>{var a8=Ug().SourceMapGenerator,Nf=qs(),c8=/(\r?\n)/,l8=10,Js="$$$isSourceNode$$$";function ir(e,t,r,n,o){this.children=[],this.sourceContents={},this.line=e??null,this.column=t??null,this.source=r??null,this.name=o??null,this[Js]=!0,n!=null&&this.add(n)}ir.fromStringWithSourceMap=function(t,r,n){var o=new ir,i=t.split(c8),s=0,a=function(){var A=g(),f=g()||"";return A+f;function g(){return s<i.length?i[s++]:void 0}},c=1,l=0,u=null;return r.eachMapping(function(A){if(u!==null)if(c<A.generatedLine)d(u,a()),c++,l=0;else{var f=i[s]||"",g=f.substr(0,A.generatedColumn-l);i[s]=f.substr(A.generatedColumn-l),l=A.generatedColumn,d(u,g),u=A;return}for(;c<A.generatedLine;)o.add(a()),c++;if(l<A.generatedColumn){var f=i[s]||"";o.add(f.substr(0,A.generatedColumn)),i[s]=f.substr(A.generatedColumn),l=A.generatedColumn}u=A},this),s<i.length&&(u&&d(u,a()),o.add(i.splice(s).join(""))),r.sources.forEach(function(A){var f=r.sourceContentFor(A);f!=null&&(n!=null&&(A=Nf.join(n,A)),o.setSourceContent(A,f))}),o;function d(A,f){if(A===null||A.source===void 0)o.add(f);else{var g=n?Nf.join(n,A.source):A.source;o.add(new ir(A.originalLine,A.originalColumn,g,f,A.name))}}};ir.prototype.add=function(t){if(Array.isArray(t))t.forEach(function(r){this.add(r)},this);else if(t[Js]||typeof t=="string")t&&this.children.push(t);else throw new TypeError("Expected a SourceNode, string, or an array of SourceNodes and strings. Got "+t);return this};ir.prototype.prepend=function(t){if(Array.isArray(t))for(var r=t.length-1;r>=0;r--)this.prepend(t[r]);else if(t[Js]||typeof t=="string")this.children.unshift(t);else throw new TypeError("Expected a SourceNode, string, or an array of SourceNodes and strings. Got "+t);return this};ir.prototype.walk=function(t){for(var r,n=0,o=this.children.length;n<o;n++)r=this.children[n],r[Js]?r.walk(t):r!==""&&t(r,{source:this.source,line:this.line,column:this.column,name:this.name})};ir.prototype.join=function(t){var r,n,o=this.children.length;if(o>0){for(r=[],n=0;n<o-1;n++)r.push(this.children[n]),r.push(t);r.push(this.children[n]),this.children=r}return this};ir.prototype.replaceRight=function(t,r){var n=this.children[this.children.length-1];return n[Js]?n.replaceRight(t,r):typeof n=="string"?this.children[this.children.length-1]=n.replace(t,r):this.children.push("".replace(t,r)),this};ir.prototype.setSourceContent=function(t,r){this.sourceContents[Nf.toSetString(t)]=r};ir.prototype.walkSourceContents=function(t){for(var r=0,n=this.children.length;r<n;r++)this.children[r][Js]&&this.children[r].walkSourceContents(t);for(var o=Object.keys(this.sourceContents),r=0,n=o.length;r<n;r++)t(Nf.fromSetString(o[r]),this.sourceContents[o[r]])};ir.prototype.toString=function(){var t="";return this.walk(function(r){t+=r}),t};ir.prototype.toStringWithSourceMap=function(t){var r={code:"",line:1,column:0},n=new a8(t),o=!1,i=null,s=null,a=null,c=null;return this.walk(function(l,u){r.code+=l,u.source!==null&&u.line!==null&&u.column!==null?((i!==u.source||s!==u.line||a!==u.column||c!==u.name)&&n.addMapping({source:u.source,original:{line:u.line,column:u.column},generated:{line:r.line,column:r.column},name:u.name}),i=u.source,s=u.line,a=u.column,c=u.name,o=!0):o&&(n.addMapping({generated:{line:r.line,column:r.column}}),i=null,o=!1);for(var d=0,A=l.length;d<A;d++)l.charCodeAt(d)===l8?(r.line++,r.column=0,d+1===A?(i=null,o=!1):o&&n.addMapping({source:u.source,original:{line:u.line,column:u.column},generated:{line:r.line,column:r.column},name:u.name})):r.column++}),this.walkSourceContents(function(l,u){n.setSourceContent(l,u)}),{code:r.code,map:n}};Mv.SourceNode=ir});var Qv=X(Lf=>{Lf.SourceMapGenerator=Ug().SourceMapGenerator;Lf.SourceMapConsumer=Tv().SourceMapConsumer;Lf.SourceNode=Rv().SourceNode});var _v,kv,Dv=m(()=>{"use client";or();_v=p(O(),1),kv=(0,Te.createSvgIcon)((0,_v.jsx)("path",{d:"M19 19H5V5h7V3H5c-1.11 0-2 .9-2 2v14c0 1.1.89 2 2 2h14c1.1 0 2-.9 2-2v-7h-2zM14 3v2h3.59l-9.83 9.83 1.41 1.41L19 6.41V10h2V3z"}),"OpenInNew")});function Pf(e){let{children:t,...r}=e;return(0,Ff.jsxs)(Nv.Link,{...r,target:"_blank",rel:"noopener noreferrer",children:[t," ",(0,Ff.jsx)(kv,{fontSize:"small"})]})}var Ff,Nv,Lv=m(()=>{Ff=p(O(),1);Dv();Nv=p(U(),1)});function $g({text:e,extra:t}){let{classes:r}=u8(),n=t?`supporting data: ${JSON.stringify(t,null,2)}`:"",o=[e,n].filter(Boolean).join(`
 `),i=encodeURIComponent(`I got this error from JBrowse, here is the stack trace:
 
 \`\`\`
 ${e}
 \`\`\`
 ${n}
-`),s=`https://github.com/GMOD/jbrowse-components/issues/new?labels=bug&title=JBrowse+issue&body=${i}`,a=`mailto:${I1}?subject=JBrowse%202%20error&body=${i}`;return(0,zn.jsxs)(zn.Fragment,{children:[(0,zn.jsxs)(Mf.Typography,{children:["Post a new issue at"," ",(0,zn.jsx)(Tf,{href:s,children:"GitHub"})," or send an email to ",(0,zn.jsx)(Tf,{href:a,children:I1})]}),(0,zn.jsx)("pre",{className:r.pre,children:o})]})}var zn,Mf,I1,WG,S1=m(()=>{zn=p(O(),1),Mf=p(U(),1);w1();Ve();I1="jbrowse2@berkeley.edu",WG=Z()(e=>({pre:{background:(0,Mf.alpha)(e.palette.error.main,.2),border:`1px solid ${e.palette.divider}`,overflow:"auto",margin:20,maxHeight:300}}))});function Pg({message:e,children:t,variant:r="body2",...n}){let{classes:o}=YG();return(0,v1.jsx)(B1.Typography,{className:xf(o.dots,n.className),...n,variant:r,children:e||"Loading"})}var v1,B1,YG,T1=m(()=>{v1=p(O(),1),B1=p(U(),1);Ve();YG=Z()({dots:{"&::after":{display:"inline-block",content:'""',width:"1em",textAlign:"left",animation:`${Lu`
+`),s=`https://github.com/GMOD/jbrowse-components/issues/new?labels=bug&title=JBrowse+issue&body=${i}`,a=`mailto:${Fv}?subject=JBrowse%202%20error&body=${i}`;return(0,Wn.jsxs)(Wn.Fragment,{children:[(0,Wn.jsxs)(Of.Typography,{children:["Post a new issue at"," ",(0,Wn.jsx)(Pf,{href:s,children:"GitHub"})," or send an email to ",(0,Wn.jsx)(Pf,{href:a,children:Fv})]}),(0,Wn.jsx)("pre",{className:r.pre,children:o})]})}var Wn,Of,Fv,u8,Pv=m(()=>{Wn=p(O(),1),Of=p(U(),1);Lv();He();Fv="jbrowse2@berkeley.edu",u8=Z()(e=>({pre:{background:(0,Of.alpha)(e.palette.error.main,.2),border:`1px solid ${e.palette.divider}`,overflow:"auto",margin:20,maxHeight:300}}))});function Wg({message:e,children:t,variant:r="body2",...n}){let{classes:o}=f8();return(0,Ov.jsx)(Gv.Typography,{className:Mf(o.dots,n.className),...n,variant:r,children:e||"Loading"})}var Ov,Gv,f8,Uv=m(()=>{Ov=p(O(),1),Gv=p(U(),1);He();f8=Z()({dots:{"&::after":{display:"inline-block",content:'""',width:"1em",textAlign:"left",animation:`${Vu`
       0% {
         content: '';
       }
@@ -27,26 +27,24 @@ ${n}
       75% {
         content: '...';
       }
-      `} 1.2s infinite ease-in-out`}}})});var R1=K((ure,M1)=>{M1.exports=function(){var e=document.getSelection();if(!e.rangeCount)return function(){};for(var t=document.activeElement,r=[],n=0;n<e.rangeCount;n++)r.push(e.getRangeAt(n));switch(t.tagName.toUpperCase()){case"INPUT":case"TEXTAREA":t.blur();break;default:t=null;break}return e.removeAllRanges(),function(){e.type==="Caret"&&e.removeAllRanges(),e.rangeCount||r.forEach(function(o){e.addRange(o)}),t&&t.focus()}}});var k1=K((fre,_1)=>{"use strict";var qG=R1(),Q1={"text/plain":"Text","text/html":"Url",default:"Text"},zG="Copy to clipboard: #{key}, Enter";function JG(e){var t=(/mac os x/i.test(navigator.userAgent)?"\u2318":"Ctrl")+"+C";return e.replace(/#{\s*key\s*}/g,t)}function KG(e,t){var r,n,o,i,s,a,c=!1;t||(t={}),r=t.debug||!1;try{o=qG(),i=document.createRange(),s=document.getSelection(),a=document.createElement("span"),a.textContent=e,a.ariaHidden="true",a.style.all="unset",a.style.position="fixed",a.style.top=0,a.style.clip="rect(0, 0, 0, 0)",a.style.whiteSpace="pre",a.style.webkitUserSelect="text",a.style.MozUserSelect="text",a.style.msUserSelect="text",a.style.userSelect="text",a.addEventListener("copy",function(u){if(u.stopPropagation(),t.format)if(u.preventDefault(),typeof u.clipboardData>"u"){r&&console.warn("unable to use e.clipboardData"),r&&console.warn("trying IE specific stuff"),window.clipboardData.clearData();var d=Q1[t.format]||Q1.default;window.clipboardData.setData(d,e)}else u.clipboardData.clearData(),u.clipboardData.setData(t.format,e);t.onCopy&&(u.preventDefault(),t.onCopy(u.clipboardData))}),document.body.appendChild(a),i.selectNodeContents(a),s.addRange(i);var l=document.execCommand("copy");if(!l)throw new Error("copy command was unsuccessful");c=!0}catch(u){r&&console.error("unable to copy using execCommand: ",u),r&&console.warn("trying IE specific stuff");try{window.clipboardData.setData(t.format||"text",e),t.onCopy&&t.onCopy(window.clipboardData),c=!0}catch(d){r&&console.error("unable to copy using clipboardData: ",d),r&&console.error("falling back to prompt"),n=JG("message"in t?t.message:zG),window.prompt(n,e)}}finally{s&&(typeof s.removeRange=="function"?s.removeRange(i):s.removeAllRanges()),a&&document.body.removeChild(a),o()}return c}_1.exports=KG});var F1={};Bt(F1,{default:()=>P1});async function L1(e){let t=await fetch(e);if(!t.ok)throw new Error(`HTTP ${t.status} fetching ${e}: ${await t.text()}`);return t.text()}async function XG(e){return JSON.parse(await L1(e))}async function t8(e){if(Fg[e])return Fg[e];let t=new URL(e).search,r=await L1(e),n=ZG.exec(r)?.[1]??"",o=await XG(new URL(n,e).href+t),i=new N1.SourceMapConsumer(o);return Fg[e]=i,i}async function r8(e){let t=[];for(let r of e.split(`
-`)){let n=e8.exec(r);if(!n){t.push(r);continue}let o=n[2],s=(await t8(o)).originalPositionFor({line:+n[3],column:+n[4]});if(!s.source||!s.line||!s.column){t.push(r);continue}t.push(`${s.source}:${s.line}:${s.column+1} (${n[1].trim()})`)}return t.join(`
-`)}function n8(e,t){return e.startsWith("Error:")?e.slice(`${t}`.length):e}function o8(e){return typeof e=="object"&&e!==null&&"stack"in e?`${e.stack}`:""}function P1({error:e,onClose:t,extra:r}){let[n,o]=(0,Ks.useState)(),[i,s]=(0,Ks.useState)(),[a,c]=(0,Ks.useState)(!1),l=e?`${e}`:"",u=n8(o8(e),l);(0,Ks.useEffect)(()=>{(async()=>{try{o(await r8(u))}catch(f){console.error(f),o(u),s(f)}})()},[u]);let d=window.JBrowseSession?.version,A=[i?"Error loading source map, showing raw stack trace below:":"",l.length>D1?`${l.slice(0,D1)}...`:l,n||"No stack trace available",d?`JBrowse ${d}`:""].filter(Boolean).join(`
-`);return(0,Mr.jsxs)(cr.Dialog,{open:!0,onClose:t,maxWidth:"xl",children:[(0,Mr.jsxs)(cr.DialogTitle,{children:["Stack trace",(0,Mr.jsx)(cr.IconButton,{onClick:t,sx:{position:"absolute",right:8,top:8},children:(0,Mr.jsx)(bf,{})})]}),(0,Mr.jsx)(cr.DialogContent,{children:n===void 0?(0,Mr.jsx)(Pg,{variant:"h6"}):(0,Mr.jsx)(Lg,{text:A,extra:r})}),(0,Mr.jsxs)(cr.DialogActions,{children:[(0,Mr.jsx)(cr.Button,{variant:"contained",color:"secondary",onClick:async()=>{let{default:f}=await Promise.resolve().then(()=>p(k1(),1));f(A),c(!0),setTimeout(()=>{c(!1)},1e3)},children:a?"Copied!":"Copy stack trace to clipboard"}),(0,Mr.jsx)(cr.Button,{variant:"contained",color:"primary",onClick:t,children:"Close"})]})]})}var Mr,Ks,cr,N1,Fg,ZG,e8,D1,O1=m(()=>{Mr=p(O(),1),Ks=p(Q(),1);Eg();cr=p(U(),1),N1=p(y1(),1);S1();T1();Fg={},ZG=/\/\/# sourceMappingURL=(.*)/,e8=/(.*)((?:https?|file):\/\/.*):(\d+):(\d+)/;D1=1e4});function s8(e){let t="",r="is not assignable",n=e.indexOf(r);if(n!==-1){let o=e.slice(0,n+r.length),i=/.*at path "(.*)" snapshot `(.*)` is not assignable/m.exec(o);i&&(e=`Failed to load element at ${i[1]}...Failed element had snapshot`,t=i[2]);let s=/.*snapshot `(.*)` is not assignable/.exec(o);s&&(e="Failed to load element...Failed element had snapshot",t=s[1])}return t}function a8({error:e,onReset:t}){let{classes:r}=G1(),[n,o]=(0,Zs.useState)(!1);return(0,er.jsxs)("div",{className:r.iconFloat,children:[typeof e=="object"&&e&&"stack"in e?(0,er.jsx)(Xs.Tooltip,{title:"Get stack trace",children:(0,er.jsx)(Xs.IconButton,{onClick:()=>{o(!0)},color:"primary",children:(0,er.jsx)(VS,{})})}):null,t?(0,er.jsx)(Xs.Tooltip,{title:"Retry",children:(0,er.jsx)(Xs.IconButton,{onClick:t,color:"primary",children:(0,er.jsx)(GS,{})})}):null,n?(0,er.jsx)(Zs.Suspense,{fallback:null,children:(0,er.jsx)(i8,{error:e,onClose:()=>{o(!1)}})}):null]})}function c8({error:e,onReset:t}){let{classes:r}=G1(),n=`${e}`,o=n.indexOf("expected an instance of"),i=o!==-1?n.slice(0,o):n,s=s8(n);return(0,er.jsxs)(wg,{children:[i.slice(0,1e4),(0,er.jsx)(a8,{error:e,onReset:t}),s?(0,er.jsx)("pre",{className:r.bg,children:JSON.stringify(JSON.parse(s),null,2)}):null]})}var er,Zs,Xs,i8,G1,U1,H1=m(()=>{er=p(O(),1),Zs=p(Q(),1);US();jS();Xs=p(U(),1);WS();Ve();i8=(0,Zs.lazy)(()=>Promise.resolve().then(()=>(O1(),F1))),G1=Z()(e=>({bg:{background:e.palette.divider,border:"1px solid black",margin:20},iconFloat:{float:"right",marginLeft:100}}));U1=c8});var j1=K((Cre,V1)=>{"use strict";var l8=/["'&<>]/;V1.exports=u8;function u8(e){var t=""+e,r=l8.exec(t);if(!r)return t;var n,o="",i=0,s=0;for(i=r.index;i<t.length;i++){switch(t.charCodeAt(i)){case 34:n="&quot;";break;case 38:n="&amp;";break;case 39:n="&#39;";break;case 60:n="&lt;";break;case 62:n="&gt;";break;default:continue}s!==i&&(o+=t.substring(s,i)),s=i+1,o+=n}return s!==i?o+t.substring(s,i):o}});function Rf(e,t=0){let r=e.getUint32(t,!0);return e.getUint32(t+4,!0)*4294967296+r}var $1=m(()=>{});function f8(e,t){let r=new Array(t+1);r[0]=[0,0];let n=new DataView(e.buffer,e.byteOffset,e.byteLength);for(let o=0;o<t;o+=1){let i=o*Og;r[o+1]=[Rf(n,i),Rf(n,i+8)]}return r}function d8(e,t){let r=0,n=e.length;for(;r<n;){let o=r+n>>>1;e[o][1]<=t?r=o+1:n=o}return r}var Og,Uc,W1=m(()=>{$1();Og=16;Uc=class{filehandle;index;constructor({filehandle:t}){this.filehandle=t}_getIndex(){return this.index||(this.index=this._readIndex().catch(t=>{throw this.index=void 0,t})),this.index}async _readIndex(){let t=await this.filehandle.read(8,0),r=Rf(new DataView(t.buffer,t.byteOffset,t.byteLength));if(r===0)return[[0,0]];if(r>Number.MAX_SAFE_INTEGER/Og)throw new TypeError("integer overflow");let n=await this.filehandle.read(Og*r,8);return f8(n,r)}async getRelevantBlocksForRead(t,r){if(t===0)return{blocks:[],nextCompressedPosition:void 0};let n=await this._getIndex(),o=r+t,i=d8(n,r)-1,s=i+1;for(;s<n.length&&n[s][1]<o;)s+=1;return{blocks:n.slice(i,s),nextCompressedPosition:n[s]?.[0]}}}});var Gg,Ug,Hc,Eo,Vc,Y1,q1,Hg=m(()=>{Gg=0,Ug=2,Hc=4,Eo=0,Vc=1,Y1=2,q1=-5});function A8(e,t){return Object.prototype.hasOwnProperty.call(e,t)}function z1(e){for(var t=Array.prototype.slice.call(arguments,1);t.length;){var r=t.shift();if(r){if(typeof r!="object")throw new TypeError(r+"must be non-object");for(var n in r)A8(r,n)&&(e[n]=r[n])}}return e}function _f(e,t){return e.length===t?e:e.subarray?e.subarray(0,t):(e.length=t,e)}var jc,$c,ea,En,Qf,Jn,wo,Ci,Wc=m(()=>{jc={arraySet:function(e,t,r,n,o){if(t.subarray&&e.subarray){e.set(t.subarray(r,r+n),o);return}for(var i=0;i<n;i++)e[o+i]=t[r+i]},flattenChunks:function(e){var t,r,n,o,i,s;for(n=0,t=0,r=e.length;t<r;t++)n+=e[t].length;for(s=new Uint8Array(n),o=0,t=0,r=e.length;t<r;t++)i=e[t],s.set(i,o),o+=i.length;return s},Buf8:function(e){return new Uint8Array(e)},Buf16:function(e){return new Uint16Array(e)},Buf32:function(e){return new Int32Array(e)}},$c={arraySet:function(e,t,r,n,o){for(var i=0;i<n;i++)e[o+i]=t[r+i]},flattenChunks:function(e){return[].concat.apply([],e)},Buf8:function(e){return new Array(e)},Buf16:function(e){return new Array(e)},Buf32:function(e){return new Array(e)}},ea=()=>{let e=typeof Uint8Array<"u"&&typeof Uint16Array<"u"&&typeof Int32Array<"u";return ea=()=>e,e},En=(e,t,r,n,o)=>(En=ea()?jc.arraySet:$c.arraySet,En(e,t,r,n,o)),Qf=e=>(Qf=ea()?jc.flattenChunks:$c.flattenChunks,Qf(e)),Jn=e=>(Jn=ea()?jc.Buf8:$c.Buf8,Jn(e)),wo=e=>(wo=ea()?jc.Buf16:$c.Buf16,wo(e)),Ci=e=>(Ci=ea()?jc.Buf32:$c.Buf32,Ci(e))});function jg(e){var t,r,n,o,i,s=e.length,a=0;for(o=0;o<s;o++)r=e.charCodeAt(o),(r&64512)===55296&&o+1<s&&(n=e.charCodeAt(o+1),(n&64512)===56320&&(r=65536+(r-55296<<10)+(n-56320),o++)),a+=r<128?1:r<2048?2:r<65536?3:4;for(t=new Uint8Array(a),i=0,o=0;i<a;o++)r=e.charCodeAt(o),(r&64512)===55296&&o+1<s&&(n=e.charCodeAt(o+1),(n&64512)===56320&&(r=65536+(r-55296<<10)+(n-56320),o++)),r<128?t[i++]=r:r<2048?(t[i++]=192|r>>>6,t[i++]=128|r&63):r<65536?(t[i++]=224|r>>>12,t[i++]=128|r>>>6&63,t[i++]=128|r&63):(t[i++]=240|r>>>18,t[i++]=128|r>>>12&63,t[i++]=128|r>>>6&63,t[i++]=128|r&63);return t}function m8(e,t){if(t<65534&&(e.subarray&&K1()||!e.subarray&&J1()))return String.fromCharCode.apply(null,_f(e,t));for(var r="",n=0;n<t;n++)r+=String.fromCharCode(e[n]);return r}function X1(e){for(var t=new Uint8Array(e.length),r=0,n=t.length;r<n;r++)t[r]=e.charCodeAt(r);return t}function Z1(e,t){var r,n,o,i,s=t||e.length,a=new Array(s*2);for(n=0,r=0;r<s;){if(o=e[r++],o<128){a[n++]=o;continue}if(i=Vg(o),i>4){a[n++]=65533,r+=i-1;continue}for(o&=i===2?31:i===3?15:7;i>1&&r<s;)o=o<<6|e[r++]&63,i--;if(i>1){a[n++]=65533;continue}o<65536?a[n++]=o:(o-=65536,a[n++]=55296|o>>10&1023,a[n++]=56320|o&1023)}return m8(a,n)}function ev(e,t){var r;for(t=t||e.length,t>e.length&&(t=e.length),r=t-1;r>=0&&(e[r]&192)===128;)r--;return r<0||r===0?t:r+Vg(e[r])>t?r:t}var J1,K1,Vg,tv=m(()=>{Wc();J1=function(){let e=!0;try{String.fromCharCode.apply(null,[0])}catch{e=!1}return J1=()=>e,e},K1=function(){let e=!0;try{String.fromCharCode.apply(null,new Uint8Array(1))}catch{e=!1}return K1=()=>e,e},Vg=function(e){for(var t=Jn(256),r=0;r<256;r++)t[r]=r>=252?6:r>=248?5:r>=240?4:r>=224?3:r>=192?2:1;return t[254]=t[254]=1,Vg=n=>t[n],t[e]}});function $g(){this.text=0,this.time=0,this.xflags=0,this.os=0,this.extra=null,this.extra_len=0,this.name="",this.comment="",this.hcrc=0,this.done=!1}var rv=m(()=>{});function Yc(e,t,r,n){for(var o=e&65535|0,i=e>>>16&65535|0,s=0;r!==0;){s=r>2e3?2e3:r,r-=s;do o=o+t[n++]|0,i=i+o|0;while(--s);o%=65521,i%=65521}return o|i<<16|0}var nv=m(()=>{});function p8(){for(var e,t=[],r=0;r<256;r++){e=r;for(var n=0;n<8;n++)e=e&1?3988292384^e>>>1:e>>>1;t[r]=e}return t}function Rr(e,t,r,n){var o=ov(),i=n+r;e^=-1;for(var s=n;s<i;s++)e=e>>>8^o[(e^t[s])&255];return e^-1}var ov,iv=m(()=>{ov=function(){let e=p8();return ov=()=>e,e}});function Wg(e,t){var r,n,o,i,s,a,c,l,u,d,A,f,g,h,y,E,x,S,w,I,v,B,R,D,L;r=e.state,n=e.next_in,D=e.input,o=n+(e.avail_in-5),i=e.next_out,L=e.output,s=i-(t-e.avail_out),a=i+(e.avail_out-257),c=r.dmax,l=r.wsize,u=r.whave,d=r.wnext,A=r.window,f=r.hold,g=r.bits,h=r.lencode,y=r.distcode,E=(1<<r.lenbits)-1,x=(1<<r.distbits)-1;e:do{g<15&&(f+=D[n++]<<g,g+=8,f+=D[n++]<<g,g+=8),S=h[f&E];t:for(;;){if(w=S>>>24,f>>>=w,g-=w,w=S>>>16&255,w===0)L[i++]=S&65535;else if(w&16){I=S&65535,w&=15,w&&(g<w&&(f+=D[n++]<<g,g+=8),I+=f&(1<<w)-1,f>>>=w,g-=w),g<15&&(f+=D[n++]<<g,g+=8,f+=D[n++]<<g,g+=8),S=y[f&x];r:for(;;){if(w=S>>>24,f>>>=w,g-=w,w=S>>>16&255,w&16){if(v=S&65535,w&=15,g<w&&(f+=D[n++]<<g,g+=8,g<w&&(f+=D[n++]<<g,g+=8)),v+=f&(1<<w)-1,v>c){e.msg="invalid distance too far back",r.mode=kf;break e}if(f>>>=w,g-=w,w=i-s,v>w){if(w=v-w,w>u&&r.sane){e.msg="invalid distance too far back",r.mode=kf;break e}if(B=0,R=A,d===0){if(B+=l-w,w<I){I-=w;do L[i++]=A[B++];while(--w);B=i-v,R=L}}else if(d<w){if(B+=l+d-w,w-=d,w<I){I-=w;do L[i++]=A[B++];while(--w);if(B=0,d<I){w=d,I-=w;do L[i++]=A[B++];while(--w);B=i-v,R=L}}}else if(B+=d-w,w<I){I-=w;do L[i++]=A[B++];while(--w);B=i-v,R=L}for(;I>2;)L[i++]=R[B++],L[i++]=R[B++],L[i++]=R[B++],I-=3;I&&(L[i++]=R[B++],I>1&&(L[i++]=R[B++]))}else{B=i-v;do L[i++]=L[B++],L[i++]=L[B++],L[i++]=L[B++],I-=3;while(I>2);I&&(L[i++]=L[B++],I>1&&(L[i++]=L[B++]))}}else if((w&64)===0){S=y[(S&65535)+(f&(1<<w)-1)];continue r}else{e.msg="invalid distance code",r.mode=kf;break e}break}}else if((w&64)===0){S=h[(S&65535)+(f&(1<<w)-1)];continue t}else if(w&32){r.mode=g8;break e}else{e.msg="invalid literal/length code",r.mode=kf;break e}break}}while(n<o&&i<a);I=g>>3,n-=I,g-=I<<3,f&=(1<<g)-1,e.next_in=n,e.next_out=i,e.avail_in=n<o?5+(o-n):5-(n-o),e.avail_out=i<a?257+(a-i):257-(i-a),r.hold=f,r.bits=g}var kf,g8,sv=m(()=>{kf=30,g8=12});function bi(e,t,r,n,o,i,s,a){var c=a.bits,l=0,u=0,d=0,A=0,f=0,g=0,h=0,y=0,E=0,x=0,S,w,I,v,B,R=null,D=0,L,F=wo(ta+1),C=wo(ta+1),M=null,k=0,G,j,oe;for(l=0;l<=ta;l++)F[l]=0;for(u=0;u<n;u++)F[t[r+u]]++;for(f=c,A=ta;A>=1&&F[A]===0;A--);if(f>A&&(f=A),A===0)return o[i++]=1<<24|64<<16|0,o[i++]=1<<24|64<<16|0,a.bits=1,0;for(d=1;d<A&&F[d]===0;d++);for(f<d&&(f=d),y=1,l=1;l<=ta;l++)if(y<<=1,y-=F[l],y<0)return-1;if(y>0&&(e===lv||A!==1))return-1;for(C[1]=0,l=1;l<ta;l++)C[l+1]=C[l]+F[l];for(u=0;u<n;u++)t[r+u]!==0&&(s[C[t[r+u]]++]=u);if(e===lv?(R=M=s,L=19):e===Yg?(R=h8,D-=257,M=y8,k-=257,L=256):(R=x8,M=C8,L=-1),x=0,u=0,l=d,B=i,g=f,h=0,I=-1,E=1<<f,v=E-1,e===Yg&&E>av||e===uv&&E>cv)return 1;for(;;){G=l-h,s[u]<L?(j=0,oe=s[u]):s[u]>L?(j=M[k+s[u]],oe=R[D+s[u]]):(j=96,oe=0),S=1<<l-h,w=1<<g,d=w;do w-=S,o[B+(x>>h)+w]=G<<24|j<<16|oe|0;while(w!==0);for(S=1<<l-1;x&S;)S>>=1;if(S!==0?(x&=S-1,x+=S):x=0,u++,--F[l]===0){if(l===A)break;l=t[r+s[u]]}if(l>f&&(x&v)!==I){for(h===0&&(h=f),B+=d,g=l-h,y=1<<g;g+h<A&&(y-=F[g+h],!(y<=0));)g++,y<<=1;if(E+=1<<g,e===Yg&&E>av||e===uv&&E>cv)return 1;I=x&v,o[I]=f<<24|g<<16|B-i|0}}return x!==0&&(o[B+x]=l-h<<24|64<<16|0),a.bits=f,0}var ta,av,cv,lv,Yg,uv,h8,y8,x8,C8,fv=m(()=>{Wc();ta=15,av=852,cv=592,lv=0,Yg=1,uv=2,h8=[3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0],y8=[16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78],x8=[1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0],C8=[16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64]});function Nv(e){return(e>>>24&255)+(e>>>8&65280)+((e&65280)<<8)+((e&255)<<24)}function M8(){this.mode=0,this.last=!1,this.wrap=0,this.havedict=!1,this.flags=0,this.dmax=0,this.check=0,this.total=0,this.head=null,this.wbits=0,this.wsize=0,this.whave=0,this.wnext=0,this.window=null,this.hold=0,this.bits=0,this.length=0,this.offset=0,this.extra=0,this.lencode=null,this.distcode=null,this.lenbits=0,this.distbits=0,this.ncode=0,this.nlen=0,this.ndist=0,this.have=0,this.next=null,this.lens=wo(320),this.work=wo(288),this.lendyn=null,this.distdyn=null,this.sane=0,this.back=0,this.was=0}function R8(e){var t;return!e||!e.state?Qr:(t=e.state,e.total_in=e.total_out=t.total=0,e.msg="",t.wrap&&(e.adler=t.wrap&1),t.mode=Gv,t.last=0,t.havedict=0,t.dmax=32768,t.head=null,t.hold=0,t.bits=0,t.lencode=t.lendyn=Ci(B8),t.distcode=t.distdyn=Ci(T8),t.sane=1,t.back=-1,Ei)}function Q8(e){var t;return!e||!e.state?Qr:(t=e.state,t.wsize=0,t.whave=0,t.wnext=0,R8(e))}function _8(e,t){var r,n;return!e||!e.state||(n=e.state,t<0?(r=0,t=-t):(r=(t>>4)+1,t<48&&(t&=15)),t&&(t<8||t>15))?Qr:(n.window!==null&&n.wbits!==t&&(n.window=null),n.wrap=r,n.wbits=t,Q8(e))}function Uv(e,t){var r,n;return e?(n=new M8,e.state=n,n.window=null,r=_8(e,t),r!==Ei&&(e.state=null),r):Qr}function k8(e){if(Lv){var t;for(Kg=Ci(512),Xg=Ci(32),t=0;t<144;)e.lens[t++]=8;for(;t<256;)e.lens[t++]=9;for(;t<280;)e.lens[t++]=7;for(;t<288;)e.lens[t++]=8;for(bi(Pv,e.lens,0,288,Kg,0,e.work,{bits:9}),t=0;t<32;)e.lens[t++]=5;bi(Fv,e.lens,0,32,Xg,0,e.work,{bits:5}),Lv=!1}e.lencode=Kg,e.lenbits=9,e.distcode=Xg,e.distbits=5}function Hv(e,t,r,n){var o,i=e.state;return i.window===null&&(i.wsize=1<<i.wbits,i.wnext=0,i.whave=0,i.window=Jn(i.wsize)),n>=i.wsize?(En(i.window,t,r-i.wsize,i.wsize,0),i.wnext=0,i.whave=i.wsize):(o=i.wsize-i.wnext,o>n&&(o=n),En(i.window,t,r-n,o,i.wnext),n-=o,n?(En(i.window,t,r-n,n,0),i.wnext=n,i.whave=i.wsize):(i.wnext+=o,i.wnext===i.wsize&&(i.wnext=0),i.whave<i.wsize&&(i.whave+=o))),0}function Vv(e,t){var r,n,o,i,s,a,c,l,u,d,A,f,g,h,y=0,E,x,S,w,I,v,B,R,D=Jn(4),L,F,C=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15];if(!e||!e.state||!e.output||!e.input&&e.avail_in!==0)return Qr;r=e.state,r.mode===Kn&&(r.mode=qg),s=e.next_out,o=e.output,c=e.avail_out,i=e.next_in,n=e.input,a=e.avail_in,l=r.hold,u=r.bits,d=a,A=c,R=Ei;e:for(;;)switch(r.mode){case Gv:if(r.wrap===0){r.mode=qg;break}for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(r.wrap&2&&l===35615){r.check=0,D[0]=l&255,D[1]=l>>>8&255,r.check=Rr(r.check,D,2,0),l=0,u=0,r.mode=mv;break}if(r.flags=0,r.head&&(r.head.done=!1),!(r.wrap&1)||(((l&255)<<8)+(l>>8))%31){e.msg="incorrect header check",r.mode=Le;break}if((l&15)!==Av){e.msg="unknown compression method",r.mode=Le;break}if(l>>>=4,u-=4,B=(l&15)+8,r.wbits===0)r.wbits=B;else if(B>r.wbits){e.msg="invalid window size",r.mode=Le;break}r.dmax=1<<B,e.adler=r.check=1,r.mode=l&512?Ev:Kn,l=0,u=0;break;case mv:for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(r.flags=l,(r.flags&255)!==Av){e.msg="unknown compression method",r.mode=Le;break}if(r.flags&57344){e.msg="unknown header flags set",r.mode=Le;break}r.head&&(r.head.text=l>>8&1),r.flags&512&&(D[0]=l&255,D[1]=l>>>8&255,r.check=Rr(r.check,D,2,0)),l=0,u=0,r.mode=pv;case pv:for(;u<32;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.head&&(r.head.time=l),r.flags&512&&(D[0]=l&255,D[1]=l>>>8&255,D[2]=l>>>16&255,D[3]=l>>>24&255,r.check=Rr(r.check,D,4,0)),l=0,u=0,r.mode=gv;case gv:for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.head&&(r.head.xflags=l&255,r.head.os=l>>8),r.flags&512&&(D[0]=l&255,D[1]=l>>>8&255,r.check=Rr(r.check,D,2,0)),l=0,u=0,r.mode=hv;case hv:if(r.flags&1024){for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.length=l,r.head&&(r.head.extra_len=l),r.flags&512&&(D[0]=l&255,D[1]=l>>>8&255,r.check=Rr(r.check,D,2,0)),l=0,u=0}else r.head&&(r.head.extra=null);r.mode=yv;case yv:if(r.flags&1024&&(f=r.length,f>a&&(f=a),f&&(r.head&&(B=r.head.extra_len-r.length,r.head.extra||(r.head.extra=new Array(r.head.extra_len)),En(r.head.extra,n,i,f,B)),r.flags&512&&(r.check=Rr(r.check,n,f,i)),a-=f,i+=f,r.length-=f),r.length))break e;r.length=0,r.mode=xv;case xv:if(r.flags&2048){if(a===0)break e;f=0;do B=n[i+f++],r.head&&B&&r.length<65536&&(r.head.name+=String.fromCharCode(B));while(B&&f<a);if(r.flags&512&&(r.check=Rr(r.check,n,f,i)),a-=f,i+=f,B)break e}else r.head&&(r.head.name=null);r.length=0,r.mode=Cv;case Cv:if(r.flags&4096){if(a===0)break e;f=0;do B=n[i+f++],r.head&&B&&r.length<65536&&(r.head.comment+=String.fromCharCode(B));while(B&&f<a);if(r.flags&512&&(r.check=Rr(r.check,n,f,i)),a-=f,i+=f,B)break e}else r.head&&(r.head.comment=null);r.mode=bv;case bv:if(r.flags&512){for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(l!==(r.check&65535)){e.msg="header crc mismatch",r.mode=Le;break}l=0,u=0}r.head&&(r.head.hcrc=r.flags>>9&1,r.head.done=!0),e.adler=r.check=0,r.mode=Kn;break;case Ev:for(;u<32;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}e.adler=r.check=Nv(l),l=0,u=0,r.mode=Pf;case Pf:if(r.havedict===0)return e.next_out=s,e.avail_out=c,e.next_in=i,e.avail_in=a,r.hold=l,r.bits=u,I8;e.adler=r.check=1,r.mode=Kn;case Kn:if(t===E8||t===Df)break e;case qg:if(r.last){l>>>=u&7,u-=u&7,r.mode=Jg;break}for(;u<3;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}switch(r.last=l&1,l>>>=1,u-=1,l&3){case 0:r.mode=wv;break;case 1:if(k8(r),r.mode=Nf,t===Df){l>>>=2,u-=2;break e}break;case 2:r.mode=Sv;break;case 3:e.msg="invalid block type",r.mode=Le}l>>>=2,u-=2;break;case wv:for(l>>>=u&7,u-=u&7;u<32;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if((l&65535)!==(l>>>16^65535)){e.msg="invalid stored block lengths",r.mode=Le;break}if(r.length=l&65535,l=0,u=0,r.mode=zg,t===Df)break e;case zg:r.mode=Iv;case Iv:if(f=r.length,f){if(f>a&&(f=a),f>c&&(f=c),f===0)break e;En(o,n,i,f,s),a-=f,i+=f,c-=f,s+=f,r.length-=f;break}r.mode=Kn;break;case Sv:for(;u<14;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(r.nlen=(l&31)+257,l>>>=5,u-=5,r.ndist=(l&31)+1,l>>>=5,u-=5,r.ncode=(l&15)+4,l>>>=4,u-=4,r.nlen>286||r.ndist>30){e.msg="too many length or distance symbols",r.mode=Le;break}r.have=0,r.mode=vv;case vv:for(;r.have<r.ncode;){for(;u<3;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.lens[C[r.have++]]=l&7,l>>>=3,u-=3}for(;r.have<19;)r.lens[C[r.have++]]=0;if(r.lencode=r.lendyn,r.lenbits=7,L={bits:r.lenbits},R=bi(b8,r.lens,0,19,r.lencode,0,r.work,L),r.lenbits=L.bits,R){e.msg="invalid code lengths set",r.mode=Le;break}r.have=0,r.mode=Bv;case Bv:for(;r.have<r.nlen+r.ndist;){for(;y=r.lencode[l&(1<<r.lenbits)-1],E=y>>>24,x=y>>>16&255,S=y&65535,!(E<=u);){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(S<16)l>>>=E,u-=E,r.lens[r.have++]=S;else{if(S===16){for(F=E+2;u<F;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(l>>>=E,u-=E,r.have===0){e.msg="invalid bit length repeat",r.mode=Le;break}B=r.lens[r.have-1],f=3+(l&3),l>>>=2,u-=2}else if(S===17){for(F=E+3;u<F;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}l>>>=E,u-=E,B=0,f=3+(l&7),l>>>=3,u-=3}else{for(F=E+7;u<F;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}l>>>=E,u-=E,B=0,f=11+(l&127),l>>>=7,u-=7}if(r.have+f>r.nlen+r.ndist){e.msg="invalid bit length repeat",r.mode=Le;break}for(;f--;)r.lens[r.have++]=B}}if(r.mode===Le)break;if(r.lens[256]===0){e.msg="invalid code -- missing end-of-block",r.mode=Le;break}if(r.lenbits=9,L={bits:r.lenbits},R=bi(Pv,r.lens,0,r.nlen,r.lencode,0,r.work,L),r.lenbits=L.bits,R){e.msg="invalid literal/lengths set",r.mode=Le;break}if(r.distbits=6,r.distcode=r.distdyn,L={bits:r.distbits},R=bi(Fv,r.lens,r.nlen,r.ndist,r.distcode,0,r.work,L),r.distbits=L.bits,R){e.msg="invalid distances set",r.mode=Le;break}if(r.mode=Nf,t===Df)break e;case Nf:r.mode=Lf;case Lf:if(a>=6&&c>=258){e.next_out=s,e.avail_out=c,e.next_in=i,e.avail_in=a,r.hold=l,r.bits=u,Wg(e,A),s=e.next_out,o=e.output,c=e.avail_out,i=e.next_in,n=e.input,a=e.avail_in,l=r.hold,u=r.bits,r.mode===Kn&&(r.back=-1);break}for(r.back=0;y=r.lencode[l&(1<<r.lenbits)-1],E=y>>>24,x=y>>>16&255,S=y&65535,!(E<=u);){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(x&&(x&240)===0){for(w=E,I=x,v=S;y=r.lencode[v+((l&(1<<w+I)-1)>>w)],E=y>>>24,x=y>>>16&255,S=y&65535,!(w+E<=u);){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}l>>>=w,u-=w,r.back+=w}if(l>>>=E,u-=E,r.back+=E,r.length=S,x===0){r.mode=_v;break}if(x&32){r.back=-1,r.mode=Kn;break}if(x&64){e.msg="invalid literal/length code",r.mode=Le;break}r.extra=x&15,r.mode=Tv;case Tv:if(r.extra){for(F=r.extra;u<F;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.length+=l&(1<<r.extra)-1,l>>>=r.extra,u-=r.extra,r.back+=r.extra}r.was=r.length,r.mode=Mv;case Mv:for(;y=r.distcode[l&(1<<r.distbits)-1],E=y>>>24,x=y>>>16&255,S=y&65535,!(E<=u);){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if((x&240)===0){for(w=E,I=x,v=S;y=r.distcode[v+((l&(1<<w+I)-1)>>w)],E=y>>>24,x=y>>>16&255,S=y&65535,!(w+E<=u);){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}l>>>=w,u-=w,r.back+=w}if(l>>>=E,u-=E,r.back+=E,x&64){e.msg="invalid distance code",r.mode=Le;break}r.offset=S,r.extra=x&15,r.mode=Rv;case Rv:if(r.extra){for(F=r.extra;u<F;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.offset+=l&(1<<r.extra)-1,l>>>=r.extra,u-=r.extra,r.back+=r.extra}if(r.offset>r.dmax){e.msg="invalid distance too far back",r.mode=Le;break}r.mode=Qv;case Qv:if(c===0)break e;if(f=A-c,r.offset>f){if(f=r.offset-f,f>r.whave&&r.sane){e.msg="invalid distance too far back",r.mode=Le;break}f>r.wnext?(f-=r.wnext,g=r.wsize-f):g=r.wnext-f,f>r.length&&(f=r.length),h=r.window}else h=o,g=s-r.offset,f=r.length;f>c&&(f=c),c-=f,r.length-=f;do o[s++]=h[g++];while(--f);r.length===0&&(r.mode=Lf);break;case _v:if(c===0)break e;o[s++]=r.length,c--,r.mode=Lf;break;case Jg:if(r.wrap){for(;u<32;){if(a===0)break e;a--,l|=n[i++]<<u,u+=8}if(A-=c,e.total_out+=A,r.total+=A,A&&(e.adler=r.check=r.flags?Rr(r.check,o,A,s-A):Yc(r.check,o,A,s-A)),A=c,(r.flags?l:Nv(l))!==r.check){e.msg="incorrect data check",r.mode=Le;break}l=0,u=0}r.mode=kv;case kv:if(r.wrap&&r.flags){for(;u<32;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(l!==(r.total&4294967295)){e.msg="incorrect length check",r.mode=Le;break}l=0,u=0}r.mode=Dv;case Dv:R=w8;break e;case Le:R=Ov;break e;case eh:return Zg;case v8:default:return Qr}return e.next_out=s,e.avail_out=c,e.next_in=i,e.avail_in=a,r.hold=l,r.bits=u,(r.wsize||A!==e.avail_out&&r.mode<Le&&(r.mode<Jg||t!==dv))&&Hv(e,e.output,e.next_out,A-e.avail_out)?(r.mode=eh,Zg):(d-=e.avail_in,A-=e.avail_out,e.total_in+=d,e.total_out+=A,r.total+=A,r.wrap&&A&&(e.adler=r.check=r.flags?Rr(r.check,o,A,e.next_out-A):Yc(r.check,o,A,e.next_out-A)),e.data_type=r.bits+(r.last?64:0)+(r.mode===Kn?128:0)+(r.mode===Nf||r.mode===zg?256:0),(d===0&&A===0||t===dv)&&R===Ei&&(R=S8),R)}function jv(e){if(!e||!e.state)return Qr;var t=e.state;return t.window&&(t.window=null),e.state=null,Ei}function $v(e,t){var r;return!e||!e.state||(r=e.state,(r.wrap&2)===0)?Qr:(r.head=t,t.done=!1,Ei)}function th(e,t){var r=t.length,n,o,i;return!e||!e.state||(n=e.state,n.wrap!==0&&n.mode!==Pf)?Qr:n.mode===Pf&&(o=1,o=Yc(o,t,r,0),o!==n.check)?Ov:(i=Hv(e,t,r,r),i?(n.mode=eh,Zg):(n.havedict=1,Ei))}var b8,Pv,Fv,dv,E8,Df,Ei,w8,I8,Qr,Ov,Zg,S8,Av,Gv,mv,pv,gv,hv,yv,xv,Cv,bv,Ev,Pf,Kn,qg,wv,zg,Iv,Sv,vv,Bv,Nf,Lf,Tv,Mv,Rv,Qv,_v,Jg,kv,Dv,Le,eh,v8,B8,T8,Lv,Kg,Xg,Wv=m(()=>{nv();iv();sv();fv();Wc();b8=0,Pv=1,Fv=2,dv=4,E8=5,Df=6,Ei=0,w8=1,I8=2,Qr=-2,Ov=-3,Zg=-4,S8=-5,Av=8,Gv=1,mv=2,pv=3,gv=4,hv=5,yv=6,xv=7,Cv=8,bv=9,Ev=10,Pf=11,Kn=12,qg=13,wv=14,zg=15,Iv=16,Sv=17,vv=18,Bv=19,Nf=20,Lf=21,Tv=22,Mv=23,Rv=24,Qv=25,_v=26,Jg=27,kv=28,Dv=29,Le=30,eh=31,v8=32,B8=852,T8=592;Lv=!0});var Ff,Yv=m(()=>{Ff={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible version"}});function rh(){this.input=null,this.next_in=0,this.avail_in=0,this.total_in=0,this.output=null,this.next_out=0,this.avail_out=0,this.total_out=0,this.msg="",this.state=null,this.data_type=2,this.adler=0}var qv=m(()=>{});function D8(e,t){var r=new oh(t);if(r.push(e,!0),r.err)throw r.msg||Ff[r.err];return r.result}var nh,oh,zv,Jv=m(()=>{Wc();tv();Hg();rv();Wv();Yv();qv();nh=Object.prototype.toString,oh=class e{constructor(t){if(!(this instanceof e))return new e(t);this.options=z1({chunkSize:16384,windowBits:0,to:""},t||{});var r=this.options;r.raw&&r.windowBits>=0&&r.windowBits<16&&(r.windowBits=-r.windowBits,r.windowBits===0&&(r.windowBits=-15)),r.windowBits>=0&&r.windowBits<16&&!(t&&t.windowBits)&&(r.windowBits+=32),r.windowBits>15&&r.windowBits<48&&(r.windowBits&15)===0&&(r.windowBits|=15),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new rh,this.strm.avail_out=0;var n=Uv(this.strm,r.windowBits);if(n!==Eo)throw new Error(Ff[n]);if(this.header=new $g,$v(this.strm,this.header),r.dictionary&&(typeof r.dictionary=="string"?r.dictionary=jg(r.dictionary):nh.call(r.dictionary)==="[object ArrayBuffer]"&&(r.dictionary=new Uint8Array(r.dictionary)),r.raw&&(n=th(this.strm,r.dictionary),n!==Eo)))throw new Error(Ff[n])}push(t,r){var n=this.strm,o=this.options.chunkSize,i=this.options.dictionary,s,a,c,l,u,d,A=!1;if(this.ended)return!1;a=r===~~r?r:r===!0?Hc:Gg,typeof t=="string"?n.input=X1(t):nh.call(t)==="[object ArrayBuffer]"?n.input=new Uint8Array(t):n.input=t,n.next_in=0,n.avail_in=n.input.length;do{if(n.avail_out===0&&(n.output=Jn(o),n.next_out=0,n.avail_out=o),s=Vv(n,Gg),s===Y1&&i&&(typeof i=="string"?d=jg(i):nh.call(i)==="[object ArrayBuffer]"?d=new Uint8Array(i):d=i,s=th(this.strm,d)),s===q1&&A===!0&&(s=Eo,A=!1),s!==Vc&&s!==Eo)return this.onEnd(s),this.ended=!0,!1;n.next_out&&(n.avail_out===0||s===Vc||n.avail_in===0&&(a===Hc||a===Ug))&&(this.options.to==="string"?(c=ev(n.output,n.next_out),l=n.next_out-c,u=Z1(n.output,c),n.next_out=l,n.avail_out=o-l,l&&En(n.output,n.output,c,l,0),this.onData(u)):this.onData(_f(n.output,n.next_out))),n.avail_in===0&&n.avail_out===0&&(A=!0)}while((n.avail_in>0||n.avail_out===0)&&s!==Vc);return s===Vc&&(a=Hc),a===Hc?(s=jv(this.strm),this.onEnd(s),this.ended=!0,s===Eo):(a===Ug&&(this.onEnd(Eo),n.avail_out=0),!0)}onData(t){this.chunks.push(t)}onEnd(t){t===Eo&&(this.options.to==="string"?this.result=this.chunks.join(""):this.result=Qf(this.chunks)),this.chunks=[],this.err=t,this.msg=this.strm.msg}};zv=D8});var Kv=m(()=>{});var Xv=m(()=>{Hg();Jv();Kv()});function tB(e){try{let s=xe.__wbindgen_add_to_stack_pointer(-16),a=oB(e,xe.__wbindgen_export2),c=lh;xe.decompress_all(s,a,c);var t=lr().getInt32(s+0,!0),r=lr().getInt32(s+4,!0),n=lr().getInt32(s+8,!0),o=lr().getInt32(s+12,!0);if(o)throw iB(n);var i=rB(t,r).slice();return xe.__wbindgen_export(t,r*1,1),i}finally{xe.__wbindgen_add_to_stack_pointer(16)}}function L8(e,t,r,n,o){try{let c=xe.__wbindgen_add_to_stack_pointer(-16),l=oB(e,xe.__wbindgen_export2),u=lh;xe.decompress_chunk_slice(c,l,u,t,r,n,o);var i=lr().getInt32(c+0,!0),s=lr().getInt32(c+4,!0),a=lr().getInt32(c+8,!0);if(a)throw iB(s);return na.__wrap(i)}finally{xe.__wbindgen_add_to_stack_pointer(16)}}function P8(e,t){let r=Error(nB(e,t));return O8(r)}function F8(e,t){throw new Error(nB(e,t))}function O8(e){zc===Xn.length&&Xn.push(Xn.length+1);let t=zc;return zc=Xn[t],Xn[t]=e,t}function G8(e){e<1028||(Xn[e]=zc,zc=e)}function eB(e,t){return e=e>>>0,U8().subarray(e/8,e/8+t)}function rB(e,t){return e=e>>>0,ch().subarray(e/1,e/1+t)}function lr(){return(ra===null||ra.buffer.detached===!0||ra.buffer.detached===void 0&&ra.buffer!==xe.memory.buffer)&&(ra=new DataView(xe.memory.buffer)),ra}function U8(){return(Of===null||Of.byteLength===0)&&(Of=new Float64Array(xe.memory.buffer)),Of}function nB(e,t){return j8(e>>>0,t)}function ch(){return(Gf===null||Gf.byteLength===0)&&(Gf=new Uint8Array(xe.memory.buffer)),Gf}function H8(e){return Xn[e]}function oB(e,t){let r=t(e.length*1,1)>>>0;return ch().set(e,r/1),lh=e.length,r}function iB(e){let t=H8(e);return G8(e),t}function j8(e,t){return ih+=t,ih>=V8&&(Uf=new TextDecoder("utf-8",{ignoreBOM:!0,fatal:!0}),Uf.decode(),ih=t),Uf.decode(ch().subarray(e,e+t))}function sB(e){xe=e}async function $8(){return qc||(sh||(sh=(async()=>{let t=await(await fetch(N8)).arrayBuffer(),{instance:r}=await WebAssembly.instantiate(t,{"./bgzf_wasm_bg.js":ah});return qc=r.exports,sB(qc),qc})()),sh)}async function aB(e){return await $8(),tB(e)}var wi,ah,N8,na,Zv,ra,Of,Gf,Xn,zc,Uf,V8,ih,lh,xe,qc,sh,cB=m(()=>{wi={};wi.d=(e,t)=>{for(var r in t)wi.o(t,r)&&!wi.o(e,r)&&Object.defineProperty(e,r,{enumerable:!0,get:t[r]})};wi.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t);wi.r=e=>{typeof Symbol<"u"&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0})};ah={};wi.r(ah);wi.d(ah,{ChunkSliceResult:()=>na,__wbg_Error_ef53bc310eb298a0:()=>P8,__wbg___wbindgen_throw_1506f2235d1bdba0:()=>F8,__wbg_set_wasm:()=>sB,decompress_all:()=>tB,decompress_chunk_slice:()=>L8});N8="data:application/wasm;base64,AGFzbQEAAAABfRFgAABgAAF/YAF/AGABfwF/YAJ/fwBgAn9/AX9gA39/fwBgA39/fwF/YAR/f39/AGAEf39/fwF/YAV/f39/fwBgBX9/f39/AX9gBn9/f39/fwBgBn9/f39/fwF/YAd/f39/f39/AX9gCH9/f39/f39/AX9gB39/f3x8fHwAAm4CES4vYmd6Zl93YXNtX2JnLmpzJ19fd2JnX19fd2JpbmRnZW5fdGhyb3dfMTUwNmYyMjM1ZDFiZGJhMAAEES4vYmd6Zl93YXNtX2JnLmpzHF9fd2JnX0Vycm9yX2VmNTNiYzMxMGViMjk4YTAABQNqaQMODwUQCQINBwkIBAYFBAQIBQUEChAGBAcEBAcEDAwKBgQCAgwCBgYHBAMGBQMEBgYFBQsEBgICBAQFAwICAQQCBQIEBgYNAgQEBwkCBAUFBgQHAAMFBQAEAAQEBAUEBQICAgIEBAUAAAQFAXABGRkFAwEAEQYJAX8BQYCAwAALB4ICCgZtZW1vcnkCABtfX3diZ19jaHVua3NsaWNlcmVzdWx0X2ZyZWUAFRxjaHVua3NsaWNlcmVzdWx0X3Rha2VfYnVmZmVyAB4gY2h1bmtzbGljZXJlc3VsdF90YWtlX2Nwb3NpdGlvbnMAGyBjaHVua3NsaWNlcmVzdWx0X3Rha2VfZHBvc2l0aW9ucwAcDmRlY29tcHJlc3NfYWxsABgWZGVjb21wcmVzc19jaHVua19zbGljZQAXH19fd2JpbmRnZW5fYWRkX3RvX3N0YWNrX3BvaW50ZXIAVhFfX3diaW5kZ2VuX2V4cG9ydABHEl9fd2JpbmRnZW5fZXhwb3J0MgAzCR4BAEEBCxg9RGY8KztnQioUVFAwT10+NBkjS0oTX1EKs8IBac0kAgl/AX4jAEEQayIBJAACQAJAAkACQCAAQfUBSQ0AAkAgAEHM/3tNDQBBACEADAQLIABBC2oiAkF4cSEDQQAoAoSdQCIERQ0CQR8hBSAAQfX//wdPDQEgA0EmIAJBCHZnIgBrdkEBcSAAQQF0a0E+aiEFDAELAkACQAJAAkACQAJAQQAoAoCdQCIGQRAgAEELakH4A3EgAEELSRsiA0EDdiICdiIAQQNxRQ0AIABBf3NBAXEgAmoiB0EDdCIDQfiawABqIgAgA0GAm8AAaigCACICKAIIIghGDQEgCCAANgIMIAAgCDYCCAwCCyADQQAoAoidQE0NBiAADQJBACgChJ1AIgBFDQYgAGhBAnRB6JnAAGooAgAiCCgCBEF4cSADayECIAghBgNAAkAgCCgCECIADQAgCCgCFCIADQAgBigCGCEFAkACQAJAIAYoAgwiACAGRw0AIAZBFEEQIAYoAhQiABtqKAIAIggNAUEAIQAMAgsgBigCCCIIIAA2AgwgACAINgIIDAELIAZBFGogBkEQaiAAGyEHA0AgByEJIAgiAEEUaiAAQRBqIAAoAhQiCBshByAAQRRBECAIG2ooAgAiCA0ACyAJQQA2AgALIAVFDQYCQAJAIAYgBigCHEECdEHomcAAaiIIKAIARg0AAkAgBSgCECAGRg0AIAUgADYCFCAADQIMCQsgBSAANgIQIAANAQwICyAIIAA2AgAgAEUNBgsgACAFNgIYAkAgBigCECIIRQ0AIAAgCDYCECAIIAA2AhgLIAYoAhQiCEUNBiAAIAg2AhQgCCAANgIYDAYLIAAoAgRBeHEgA2siCCACIAggAkkiCBshAiAAIAYgCBshBiAAIQgMAAsLQQAgBkF+IAd3cTYCgJ1ACyACQQhqIQAgAiADQQNyNgIEIAIgA2oiAyADKAIEQQFyNgIEDAULAkACQCAAIAJ0QQIgAnQiAEEAIABrcnFoIglBA3QiAkH4msAAaiIIIAJBgJvAAGooAgAiACgCCCIHRg0AIAcgCDYCDCAIIAc2AggMAQtBACAGQX4gCXdxNgKAnUALIAAgA0EDcjYCBCAAIANqIgYgAiADayIIQQFyNgIEIAAgAmogCDYCAAJAQQAoAoidQCICRQ0AQQAoApCdQCEDAkACQEEAKAKAnUAiB0EBIAJBA3Z0IglxDQBBACAHIAlyNgKAnUAgAkF4cUH4msAAaiICIQcMAQsgAkF4cSICQfiawABqIQcgAkGAm8AAaigCACECCyAHIAM2AgggAiADNgIMIAMgBzYCDCADIAI2AggLIABBCGohAEEAIAY2ApCdQEEAIAg2AoidQAwEC0EAQQAoAoSdQEF+IAYoAhx3cTYChJ1ACwJAAkACQCACQRBJDQAgBiADQQNyNgIEIAYgA2oiCCACQQFyNgIEIAggAmogAjYCAEEAKAKInUAiB0UNAUEAKAKQnUAhAAJAAkBBACgCgJ1AIglBASAHQQN2dCIFcQ0AQQAgCSAFcjYCgJ1AIAdBeHFB+JrAAGoiByEJDAELIAdBeHEiB0H4msAAaiEJIAdBgJvAAGooAgAhBwsgCSAANgIIIAcgADYCDCAAIAk2AgwgACAHNgIIDAELIAYgAiADaiIAQQNyNgIEIAYgAGoiACAAKAIEQQFyNgIEDAELQQAgCDYCkJ1AQQAgAjYCiJ1ACyAGQQhqIgBFDQEMAgtBACADayECAkACQAJAAkAgBUECdEHomcAAaigCACIGDQBBACEIQQAhAAwBC0EAIQggA0EAQRkgBUEBdmsgBUEfRht0IQdBACEAA0ACQCAGIgYoAgRBeHEiCSADSQ0AIAkgA2siCSACTw0AIAYhCCAJIQIgCQ0AQQAhAiAGIQAgBiEIDAMLIAYoAhQiCSAAIAkgBiAHQR12QQRxaigCECIGRxsgACAJGyEAIAdBAXQhByAGDQALCwJAIAAgCHINAEEAIQhBAiAFdCIAQQAgAGtyIARxIgBFDQMgAGhBAnRB6JnAAGooAgAhAAsgAEUNAQsDQCAAKAIEQXhxIgYgA2siByACIAcgAkkiCRshBSAGIANJIQcgACAIIAkbIQkCQCAAKAIQIgYNACAAKAIUIQYLIAIgBSAHGyECIAggCSAHGyEIIAYhACAGDQALCyAIRQ0AAkBBACgCiJ1AIgAgA0kNACACIAAgA2tPDQELIAgoAhghBQJAAkACQCAIKAIMIgAgCEcNACAIQRRBECAIKAIUIgAbaigCACIGDQFBACEADAILIAgoAggiBiAANgIMIAAgBjYCCAwBCyAIQRRqIAhBEGogABshBwNAIAchCSAGIgBBFGogAEEQaiAAKAIUIgYbIQcgAEEUQRAgBhtqKAIAIgYNAAsgCUEANgIACwJAIAVFDQACQAJAAkAgCCAIKAIcQQJ0QeiZwABqIgYoAgBGDQACQCAFKAIQIAhGDQAgBSAANgIUIAANAgwECyAFIAA2AhAgAA0BDAMLIAYgADYCACAARQ0BCyAAIAU2AhgCQCAIKAIQIgZFDQAgACAGNgIQIAYgADYCGAsgCCgCFCIGRQ0BIAAgBjYCFCAGIAA2AhgMAQtBAEEAKAKEnUBBfiAIKAIcd3E2AoSdQAsCQAJAIAJBEEkNACAIIANBA3I2AgQgCCADaiIAIAJBAXI2AgQgACACaiACNgIAAkAgAkGAAkkNACAAIAIQEQwCCwJAAkBBACgCgJ1AIgZBASACQQN2dCIHcQ0AQQAgBiAHcjYCgJ1AIAJB+AFxQfiawABqIgIhBgwBCyACQfgBcSICQfiawABqIQYgAkGAm8AAaigCACECCyAGIAA2AgggAiAANgIMIAAgBjYCDCAAIAI2AggMAQsgCCACIANqIgBBA3I2AgQgCCAAaiIAIAAoAgRBAXI2AgQLIAhBCGoiAA0BCwJAAkACQAJAAkACQEEAKAKInUAiACADTw0AAkBBACgCjJ1AIgAgA0sNACABQQRqQaydwAAgA0GvgARqQYCAfHEQKAJAIAEoAgQiBg0AQQAhAAwICyABKAIMIQVBAEEAKAKYnUAgASgCCCIJaiIANgKYnUBBACAAQQAoApydQCICIAAgAksbNgKcnUACQAJAAkBBACgClJ1AIgJFDQBB6JrAACEAA0AgBiAAKAIAIgggACgCBCIHakYNAiAAKAIIIgANAAwDCwsCQAJAQQAoAqSdQCIARQ0AIAYgAE8NAQtBACAGNgKknUALQQBB/x82AqidQEEAIAU2AvSaQEEAIAk2AuyaQEEAIAY2AuiaQEEAQfiawAA2AoSbQEEAQYCbwAA2AoybQEEAQfiawAA2AoCbQEEAQYibwAA2ApSbQEEAQYCbwAA2AoibQEEAQZCbwAA2ApybQEEAQYibwAA2ApCbQEEAQZibwAA2AqSbQEEAQZCbwAA2ApibQEEAQaCbwAA2AqybQEEAQZibwAA2AqCbQEEAQaibwAA2ArSbQEEAQaCbwAA2AqibQEEAQbCbwAA2ArybQEEAQaibwAA2ArCbQEEAQbibwAA2AsSbQEEAQbCbwAA2AribQEEAQbibwAA2AsCbQEEAQcCbwAA2AsybQEEAQcCbwAA2AsibQEEAQcibwAA2AtSbQEEAQcibwAA2AtCbQEEAQdCbwAA2AtybQEEAQdCbwAA2AtibQEEAQdibwAA2AuSbQEEAQdibwAA2AuCbQEEAQeCbwAA2AuybQEEAQeCbwAA2AuibQEEAQeibwAA2AvSbQEEAQeibwAA2AvCbQEEAQfCbwAA2AvybQEEAQfCbwAA2AvibQEEAQfibwAA2AoScQEEAQYCcwAA2AoycQEEAQfibwAA2AoCcQEEAQYicwAA2ApScQEEAQYCcwAA2AoicQEEAQZCcwAA2ApycQEEAQYicwAA2ApCcQEEAQZicwAA2AqScQEEAQZCcwAA2ApicQEEAQaCcwAA2AqycQEEAQZicwAA2AqCcQEEAQaicwAA2ArScQEEAQaCcwAA2AqicQEEAQbCcwAA2ArycQEEAQaicwAA2ArCcQEEAQbicwAA2AsScQEEAQbCcwAA2AricQEEAQcCcwAA2AsycQEEAQbicwAA2AsCcQEEAQcicwAA2AtScQEEAQcCcwAA2AsicQEEAQdCcwAA2AtycQEEAQcicwAA2AtCcQEEAQdicwAA2AuScQEEAQdCcwAA2AticQEEAQeCcwAA2AuycQEEAQdicwAA2AuCcQEEAQeicwAA2AvScQEEAQeCcwAA2AuicQEEAQfCcwAA2AvycQEEAQeicwAA2AvCcQEEAIAZBD2pBeHEiAEF4aiICNgKUnUBBAEHwnMAANgL4nEBBACAGIABrIAlBWGoiAGpBCGoiCDYCjJ1AIAIgCEEBcjYCBCAGIABqQSg2AgRBAEGAgIABNgKgnUAMCAsgAiAGTw0AIAggAksNACAAKAIMIghBAXENACAIQQF2IAVGDQMLQQBBACgCpJ1AIgAgBiAAIAZJGzYCpJ1AIAYgCWohCEHomsAAIQACQAJAAkADQCAAKAIAIgcgCEYNASAAKAIIIgANAAwCCwsgACgCDCIIQQFxDQAgCEEBdiAFRg0BC0HomsAAIQACQANAAkAgACgCACIIIAJLDQAgAiAIIAAoAgRqIghJDQILIAAoAgghAAwACwtBACAGQQ9qQXhxIgBBeGoiBzYClJ1AQQAgBiAAayAJQVhqIgBqQQhqIgQ2AoydQCAHIARBAXI2AgQgBiAAakEoNgIEQQBBgICAATYCoJ1AIAIgCEFgakF4cUF4aiIAIAAgAkEQakkbIgdBGzYCBEEAKQLomkAhCiAHQRBqQQApAvCaQDcCACAHQQhqIgAgCjcCAEEAIAU2AvSaQEEAIAk2AuyaQEEAIAY2AuiaQEEAIAA2AvCaQCAHQRxqIQADQCAAQQc2AgAgAEEEaiIAIAhJDQALIAcgAkYNByAHIAcoAgRBfnE2AgQgAiAHIAJrIgBBAXI2AgQgByAANgIAAkAgAEGAAkkNACACIAAQEQwICwJAAkBBACgCgJ1AIghBASAAQQN2dCIGcQ0AQQAgCCAGcjYCgJ1AIABB+AFxQfiawABqIgAhCAwBCyAAQfgBcSIAQfiawABqIQggAEGAm8AAaigCACEACyAIIAI2AgggACACNgIMIAIgCDYCDCACIAA2AggMBwsgACAGNgIAIAAgACgCBCAJajYCBCAGQQ9qQXhxQXhqIgggA0EDcjYCBCAHQQ9qQXhxQXhqIgIgCCADaiIAayEDIAJBACgClJ1ARg0DIAJBACgCkJ1ARg0EAkAgAigCBCIGQQNxQQFHDQAgAiAGQXhxIgYQECAGIANqIQMgAiAGaiICKAIEIQYLIAIgBkF+cTYCBCAAIANBAXI2AgQgACADaiADNgIAAkAgA0GAAkkNACAAIAMQEQwGCwJAAkBBACgCgJ1AIgJBASADQQN2dCIGcQ0AQQAgAiAGcjYCgJ1AIANB+AFxQfiawABqIgMhAgwBCyADQfgBcSIDQfiawABqIQIgA0GAm8AAaigCACEDCyACIAA2AgggAyAANgIMIAAgAjYCDCAAIAM2AggMBQtBACAAIANrIgI2AoydQEEAQQAoApSdQCIAIANqIgg2ApSdQCAIIAJBAXI2AgQgACADQQNyNgIEIABBCGohAAwGC0EAKAKQnUAhAgJAAkAgACADayIIQQ9LDQBBAEEANgKQnUBBAEEANgKInUAgAiAAQQNyNgIEIAIgAGoiACAAKAIEQQFyNgIEDAELQQAgCDYCiJ1AQQAgAiADaiIGNgKQnUAgBiAIQQFyNgIEIAIgAGogCDYCACACIANBA3I2AgQLIAJBCGohAAwFCyAAIAcgCWo2AgRBAEEAKAKUnUAiAEEPakF4cSICQXhqIgg2ApSdQEEAIAAgAmtBACgCjJ1AIAlqIgJqQQhqIgY2AoydQCAIIAZBAXI2AgQgACACakEoNgIEQQBBgICAATYCoJ1ADAMLQQAgADYClJ1AQQBBACgCjJ1AIANqIgM2AoydQCAAIANBAXI2AgQMAQtBACAANgKQnUBBAEEAKAKInUAgA2oiAzYCiJ1AIAAgA0EBcjYCBCAAIANqIAM2AgALIAhBCGohAAwBC0EAIQBBACgCjJ1AIgIgA00NAEEAIAIgA2siAjYCjJ1AQQBBACgClJ1AIgAgA2oiCDYClJ1AIAggAkEBcjYCBCAAIANBA3I2AgQgAEEIaiEACyABQRBqJAAgAAvCHQEWfyABIAJqIgcgAkERIAJBEUkbayEIIAMgBGoiCSAEQZcCIARBlwJJG2shCiAAQaTaAGohCyAAQZjJAGohDCAAQeDVAGohDSAAQcwDaiEOQQAhD0EAIRBBACECIAEhESADIQQCQANAAkACQCAHIBFrQQNLDQAgAiESIBBB/wFxIgJBF0sNAQNAAkACQCARIAdGDQAgES0AACACdCASciESIBFBAWohEQwBC0EBIRMgByERIA9BAWoiD0EESw0FCyAQQQhqIhBB/wFxIgJBGEkNAAwCCwsgESgAACAQQf8BcXQgAnIhEiARIBBBA3ZBB3FrQQNqIREgEEEYciEQC0EBIRMCQAJAAkACQAJAAkAgEkEBdkEDcQ4DBAEABwtBACEUIABBADoAoFogEEFvaiECIBJBEXYhFSASQQ12IhZBD3EiF0EEaiEQIBJBCHZBH3FBAWohGCASQQN2QR9xQYECaiEZA0ACQAJAIAJB/wFxIhNBAk0NACACIRoMAQsCQCAHIBFrQQNLDQAgAiEaA0ACQAJAIBEgB0YNACARLQAAIBN0IBVyIRUgEUEBaiERDAELQQEhEyAHIREgD0EBaiIPQQRLDQsLIBpBCGoiGkH/AXEiE0EYSQ0ADAILCyACQRhyIRogESgAACATdCAVciEVIBEgAkEDdkEHcWtBA2ohEQsgACAUQaCJwABqLQAAaiAVQQdxOgAAIBpBfWohAiAVQQN2IRUgFEEBaiIUIBBHDQALAkAgF0EPRg0AAkAgFkF/c0EDcSIURQ0AA0AgACAQQaCJwABqLQAAakEAOgAAIBBBAWohECAUQX9qIhQNAAsLIBdBdGpBA0kNAANAIAAgEEGgicAAai0AAGpBADoAACAAIBBBoYnAAGotAABqQQA6AAAgACAQQaKJwABqLQAAakEAOgAAIAAgEEGjicAAai0AAGpBADoAACAQQQRqIhBBE0cNAAsLAkAgDiAAQRNBwInAAEEHQQcgDUEAEAQNAEEBDwsgGSAYaiEXQQAhEANAAkACQCACQf8BcSIUQQ1NDQAgAiEaDAELAkAgByARa0EDSw0AIAIhGgNAAkACQCARIAdGDQAgES0AACAUdCAVciEVIBFBAWohEQwBC0EBIRMgByERIA9BAWoiD0EESw0LCyAaQQhqIhpB/wFxIhRBGEkNAAwCCwsgAkEYciEaIBEoAAAgFHQgFXIhFSARIAJBA3ZBB3FrQQNqIRELIAAgFUH/AHFBAnRqQcwDaigCACIUQRB2IRMgGiAUayECIBUgFEH/AXF2IRUCQAJAIBRB//8/Sw0AIAAgEGogEzoAACAQQQFqIRAMAQsCQAJAAkACQCATQXBqDgIAAQILAkAgEA0AQQEPCyAAIBBqIhRBBWogFEF/ai0AACIaOgAAIBRBBGogGjoAACAUQQNqIBo6AAAgFEECaiAaOgAAIBRBAWogGjoAACAUIBo6AAAgAkF+aiECIBVBA3FBA2ohFCAVQQJ2IRUMAgsgACAQaiIUQgA3AAAgFEEIakEAOwAAIAJBfWohAiAVQQdxQQNqIRQgFUEDdiEVDAELIAAgEGpBACAVQf8AcUELaiIUEB0aIAJBeWohAiAVQQd2IRULIBQgEGohEAsgECAXSQ0ACyAQIBdGDQFBAQ8LIBBBfWohAiASQQN2IRUgAC0AoFoNASAAQQE6AKBaQQAhEANAIAAgEGoiFEKIkKDAgIGChAg3AAAgFEEIakEIOgAAIBBBCWoiEEGQAUcNAAtBkH8hEANAIAAgEGpBgAJqQomSpMiQocKECTcAACAQQQhqIhANAAsgAEKFipSo0KDBggU3ALgCIABChYqUqNCgwYIFNwCwAiAAQoWKlKjQoMGCBTcAqAIgAEKFipSo0KDBggU3AKACIABCiJCgwICBgoQINwCYAiAAQoeOnLjw4MGDBzcAkAIgAEKHjpy48ODBgwc3AIgCIABCh46cuPDgwYMHNwCAAkEgIRhBoAIhGQsCQCAMIAAgGWogGEGQisAAQQhBDyANQQAQBA0AQQEPCyAAIAAgGUGQi8AAQQtBDyANIAsQBA0AQQEPC0F/IAsoAgB0QX9zIRcCQAJAIBEgCE8NACAEIApPDQAgAkEYciEQIBEgAkEDdkEHcWtBA2ohFCAAIBEoAAAgAkH/AXF0IBVyIhUgF3FBAnRqKAIAIRgDQCAQIBhrIRAgFSAYQf8BcSITdiECAkACQAJAAkAgGEEASA0AAkAgGEGAgAJxDQAgAiERDAMLAkAgGEGAwABxRQ0AIBQhEQwJCyAQIAAgAkF/IBhBCHZ0QX9zcSAYQRB2akECdGooAgAiGGshECACIBhB/wFxIhN2IREgGEEATg0BIBEhAgsgBCAYQRB2OgAAIARBAWohBCAUKAAAIBBB/wFxdCACciEVIBQgEEEDdkEHcWtBA2ohFCAAIAIgF3FBAnRqKAIAIRgMAgsgAiEVIBhBgMAAcUUNACARIQIgFCERDAYLIBBBGHIhGSAUKAAAIBBB/wFxdCARciEaIBQgEEEDdkEHcWtBA2ohFAJAIAAgEUH/AXFBAnRqQZjJAGooAgAiEUGAgAJxRQ0AIBQoAAAgGUF4aiICQfcBcXQgGkEIdiIQciEaIAAgEEF/IBFBCHZBP3F0QX9zcSARQRB2akECdGpBmMkAaigCACERIAJBGHIhGSAUIAJBA3ZBBnFrQQNqIRQLAkAgGkF/IBFB/wFxIhZ0QX9zcSARQQh2Qf8BcXYiGyARQRB2IhxqIgIgBCADa00NAEEBDwsgFUF/IBN0QX9zcSETIBQoAAAgGSARayIQQf8BcXQgGiAWdiIZciEVIAQgEyAYQQh2Qf8BcXYgGEEQdmoiE2ohESAEIAJrIRogFCAQQQN2QQdxa0EDaiEUIAAgGSAXcUECdGooAgAhGAJAAkAgAkEESQ0AIAQgGigAADYAACAEIBooAAQ2AAQgBCAaKAAINgAIIAQgGigADDYADCAEIBooABA2ABAgE0EVSA0BQQAgAmshEwNAIARBFGoiGiAEIBNqIgJBFGooAAA2AAAgBEEYaiACQRhqKAAANgAAIARBHGogAkEcaigAADYAACAEQSBqIAJBIGooAAA2AAAgBEEkaiACQSRqKAAANgAAIARBKGohAiAaIQQgAiARSQ0ADAILCwJAIAJBAUcNACAEIBotAABBgYKECGwiGjYADCAEIBo2AAggBCAaNgAEIAQgGjYAACATQRFIDQEgBEEQaiECA0AgAiAaNgAAIAJBDGogGjYAACACQQhqIBo2AAAgAkEEaiAaNgAAIAJBEGoiAiARSQ0ADAILCyAEIBooAAAiGjYAACAEIAJqIBo2AAAgG0EBdCAcQQF0aiEaIAJBA2whFgNAIAQgGmogBCACaiITKAAAIhk2AAAgBCAWaiAZNgAAIBMgAmoiBCAaaiARSQ0ACwsgESEECyAQQRhyIRAgFCAITw0CIAQgCkkNAAwCCwsgAiEQIBEhFAsDQAJAAkAgByAUa0EDSw0AIBBB/wFxIgJBF0sNAQNAAkACQCAUIAdGDQAgFC0AACACdCAVciEVIBRBAWohFAwBC0EBIRMgByEUIA9BAWoiD0EESw0ICyAQQQhqIhBB/wFxIgJBGEkNAAwCCwsgFCgAACAQQf8BcXQgFXIhFSAUIBBBA3ZBB3FrQQNqIRQgEEEYciEQCyAQIAAgFSAXcUECdGooAgAiAmshECAVIAJB/wFxdiERAkACQCACQYCAAXENACAVIRogESEVDAELIBAgACARQX8gAkEIdkE/cXRBf3NxIAJBEHZqQQJ0aigCACICayEQIBEgAkH/AXF2IRUgESEaCyACQRB2IRECQCACQX9KDQACQCAEIAlHDQBBAw8LIAQgEToAACAEQQFqIQQMAQsCQCACQYDAAHFFDQAgFSECIBQhEQwDCwJAIBpBfyACQf8BcXRBf3NxIAJBCHZB3wFxdiARaiIaIAkgBGtNDQBBAw8LAkACQCAHIBRrQQNLDQAgEEH/AXEiAkEXSw0BA0ACQAJAIBQgB0YNACAULQAAIAJ0IBVyIRUgFEEBaiEUDAELQQEhEyAHIRQgD0EBaiIPQQRLDQgLIBBBCGoiEEH/AXEiAkEYSQ0ADAILCyAUKAAAIBBB/wFxdCAVciEVIBQgEEEDdkEHcWtBA2ohFCAQQRhyIRALAkAgACAVQf8BcUECdGpBmMkAaigCACICQYCAAnFFDQAgACAVQQh2IhVBfyACQQh2QT9xdEF/c3EgAkEQdmpBAnRqQZjJAGooAgAhAiAQQXhqIRECQAJAIAcgFGtBA0sNACARQf8BcSITQRdNDQEgESEQDAILIBFBGHIhECAUKAAAIBFB/wFxdCAVciEVIBQgEUEDdkEHcWtBA2ohFAwBCwNAAkACQCAUIAdGDQAgFC0AACATdCAVciEVIBRBAWohFAwBC0EBIRMgByEUIA9BAWoiD0EESw0HCyAQQf8BcSETIBBBCGoiESEQIBNBGEkNAAsgEUF4aiEQCwJAIBVBfyACQf8BcSITdEF/c3EgAkEIdkH/AXF2IAJBEHZqIhEgBCADa00NAEEBDwsgECACayEQIBUgE3YhFSAEIAQgEWsiAi0AADoAACAEIAItAAE6AAEgBEECaiECIAQgGmohBEEAIBFrIREDQCACIAIgEWotAAA6AAAgAkEBaiICIARJDQAMAQsLCwJAIA8gEEH9AWpBA3ZBH3EiAk0NAEEBDwsCQCAHIBEgDyACa2oiEWtBBE4NAEEBDwsCQCARLwACIBEvAAAiAnNB//8DcUH//wNGDQBBAQ8LAkAgCSAEayACTg0AQQMPCwJAIAcgEUEEaiIRayACTg0AQQEPCyAEIBEgAhAaIAJqIQQgESACaiERQQAhD0EAIRBBACECCyASQQFxRQ0AC0EBIRMgDyAQQQN2QR9xIgJLDQACQCAFRQ0AIAUgESAPIAJraiABazYCAAsCQAJAIAZFDQAgBiAEIANrNgIADAELQQIhEyAEIAlHDQELQQAhEwsgEwuPDwEPfyMAQYABayIIJAAgBUEBaiIJQQdxIQpBACELAkAgBUEHSQ0AIAlBeHEhDEEAIQsgCEHAAGohCQNAIAlCADcDACAJQRhqQgA3AwAgCUEQakIANwMAIAlBCGpCADcDACAJQSBqIQkgDCALQQhqIgtHDQALCwJAIApFDQAgCEHAAGogC0ECdGohCQNAIAlBADYCACAJQQRqIQkgCkF/aiIKDQALCwJAIAJFDQAgAkEDcSELQQAhCgJAIAJBBEkNACACQXxxIQ1BACEKA0AgCEHAAGogASAKaiIJLQAAQQJ0aiIMIAwoAgBBAWo2AgAgCEHAAGogCUEBai0AAEECdGoiDCAMKAIAQQFqNgIAIAhBwABqIAlBAmotAABBAnRqIgwgDCgCAEEBajYCACAIQcAAaiAJQQNqLQAAQQJ0aiIJIAkoAgBBAWo2AgAgDSAKQQRqIgpHDQALCyALRQ0AIAEgCmohCQNAIAhBwABqIAktAABBAnRqIgogCigCAEEBajYCACAJQQFqIQkgC0F/aiILDQALCwJAAkAgBUECTw0AIAUhDgwBCyAIQcAAaiAFQQJ0aiEJA0ACQCAJKAIARQ0AIAUhDgwCCyAJQXxqIQlBASEOIAVBf2oiBUEBSw0ACwsCQCAHRQ0AIAcgDiAEIA4gBEkbIgQ2AgALQQAhCSAIQQA2AgAgCCAIKAJAIgU2AgRBASEKAkAgDkECSQ0AQQEhCSAOQX9qIgpBAXEhDwJAAkAgDkECRw0AQQAhCwwBCyAKQX5xIRAgCEHAAGpBCHIhCSAIQQxyIQpBACELQQAhDANAIApBfGogCUF8aigCACINIAVqIgU2AgAgCiAJKAIAIgcgBWoiBTYCACAHIAtBAnQgDUEBdGpqIQsgCUEIaiEJIApBCGohCiAQIAxBAmoiDEcNAAsgDEEBaiEJCwJAIA9FDQAgCUECdCIJIAhqQQRqIAhBwABqIAlqKAIAIgkgBWo2AgAgCSALQQF0aiELCyALQQF0IQkgDiEKCyAIQcAAaiAKQQJ0aigCACAJaiENAkAgAkUNACACQQFxIQdBACEJAkAgAkEBRg0AIAJBfnEhDEEAIQkDQCAGIAggASAJaiIKLQAAQQJ0aiILKAIAIgVBAXRqIAk7AQAgCyAFQQFqNgIAIAggCkEBai0AAEECdGoiCiAKKAIAIgpBAWo2AgAgBiAKQQF0aiAJQQFqOwEAIAwgCUECaiIJRw0ACwsgB0UNACAIIAEgCWotAABBAnRqIgogCigCACIKQQFqNgIAIAYgCkEBdGogCTsBAAsCQAJAIA1BASAOdCIJTQ0AQQAhBgwBCyAGIAgoAgBBAXRqIRACQAJAAkAgDSAJSQ0AIAhBwABqQQRyIQlBACEHA0AgB0EBaiEHIAkoAgAhDCAJQQRqIQkgDEUNAAtBACERIAcgBE0NAUEAIQ0MAgsCQAJAIA0NAEEAIQkMAQtBACEGIA1BASAOQX9qdEcNAyAIKAJEQQFHDQMgEC8BACEJCyADIAlBAnRqKAIAQYECaiELQQEhBkEBIQkDQCAAIAs2AgAgAEEEaiEAIAkgBHYhCiAJQQFqIQkgCkUNAAwDCwtBASAHdCEKIAhBwABqQQRyIQFBACENA0AgCkF/aiEJIAdBgQJsIQYDQCAAIA1BAnRqIAYgAyAQLwEAQQJ0aigCAGo2AgACQCANIAlHDQBBASEGIAQgB00NBEEBIQYgB0EBaiEJAkAgBCAHa0EBcUUNACAAIApBAnQiC2ogACALEBoaIApBAXQhCiAJIQcLIAQgCUYNBCAEIAdrIQsDQCAAIApBAnQiCWogACAJEBoaIAAgCkEDdCIKaiAAIAoQGhogCSEKIAtBfmoiCw0ADAULC0GAgICAeCAJIA1zZ3YiC0F/aiANcSALciENIBBBAmohECAMQX9qIgwNAAsgASAHQQJ0aiEJA0ACQCAHQQFqIgcgBEsNACAAIApBAnQiC2ogACALEBoaIApBAXQhCgsgCSgCACEMIAlBBGohCSAMRQ0ACyAHIARNDQALC0EBIAR0IgJBf2ohEiAIQcAAakEEciETQX8hCQNAIBMgB0ECdGohDkF/IAd0QX9zIRQgByAEayIVQYECbCEWQQEgFXQiBkECdCEFA0ACQAJAIA0gEnEiDyAJRw0AIAIhCyAJIQ8MAQsgFSEKIAYhAQJAIAwgBk8NACAOIQkgFSEKIAwhCwNAIAkoAgAhASAJQQRqIQkgASALQQF0aiILQQEgCkEBaiIKdCIBSQ0ACwsgACAPQQJ0aiACQRB0IApBCHRyIARyQYCAA3I2AgAgASACaiELIAIhEQsgACARIA0gBHZqIgpBAnRqIQkgFiADIBAvAQBBAnRqKAIAaiEBA0AgCSABNgIAIAkgBWohCSAKIAZqIgogC0kNAAsCQCANIBRHDQBBASEGDAMLQYCAgIB4IA0gFHNndiIJQX9qIA1xIAlyIQ0gEEECaiEQIAshAiAPIQkgDEF/aiIMDQALA0AgB0EBaiEHIA4oAgAhDCAOQQRqIQ4gDEUNAAsgCyECIA8hCQwACwsgCEGAAWokACAGC+sGAQh/AkACQCABIABBA2pBfHEiAiAAayIDSQ0AIAEgA2siBEECdiIFRQ0AIARBA3EhBkEAIQdBACEBAkAgAiAARg0AQQAhCEEAIQECQCAAIAJrIglBfEsNAEEAIQhBACEBA0AgASAAIAhqIgIsAABBv39KaiACQQFqLAAAQb9/SmogAkECaiwAAEG/f0pqIAJBA2osAABBv39KaiEBIAhBBGoiCA0ACwsgACAIaiECA0AgASACLAAAQb9/SmohASACQQFqIQIgCUEBaiIJDQALCyAAIANqIQkCQCAGRQ0AIAkgBEH8////B3FqIgIsAABBv39KIQcgBkEBRg0AIAcgAiwAAUG/f0pqIQcgBkECRg0AIAcgAiwAAkG/f0pqIQcLIAcgAWohCANAIAkhAyAFRQ0CIAVBwAEgBUHAAUkbIgdBA3EhBgJAAkAgB0ECdCIEQfAHcSIBDQBBACECDAELIAMgAWohAEEAIQIgAyEBA0AgAUEMaigCACIJQX9zQQd2IAlBBnZyQYGChAhxIAFBCGooAgAiCUF/c0EHdiAJQQZ2ckGBgoQIcSABQQRqKAIAIglBf3NBB3YgCUEGdnJBgYKECHEgASgCACIJQX9zQQd2IAlBBnZyQYGChAhxIAJqampqIQIgAUEQaiIBIABHDQALCyAFIAdrIQUgAyAEaiEJIAJBCHZB/4H8B3EgAkH/gfwHcWpBgYAEbEEQdiAIaiEIIAZFDQALIAMgB0H8AXFBAnRqIgIoAgAiAUF/c0EHdiABQQZ2ckGBgoQIcSEBAkAgBkEBRg0AIAIoAgQiCUF/c0EHdiAJQQZ2ckGBgoQIcSABaiEBIAZBAkYNACACKAIIIgJBf3NBB3YgAkEGdnJBgYKECHEgAWohAQsgAUEIdkH/gRxxIAFB/4H8B3FqQYGABGxBEHYgCGohCAwBCwJAIAENAEEADwsgAUEDcSECQQAhCUEAIQgCQCABQQRJDQAgAUF8cSEFQQAhCEEAIQkDQCAIIAAgCWoiASwAAEG/f0pqIAFBAWosAABBv39KaiABQQJqLAAAQb9/SmogAUEDaiwAAEG/f0pqIQggBSAJQQRqIglHDQALIAJFDQELIAAgCWohAQNAIAggASwAAEG/f0pqIQggAUEBaiEBIAJBf2oiAg0ACwsgCAuxBwIRfwJ8IwBB0ABrIgckACAHEEA2AgAQaQJAAkACQEGAAUEIEFciCEUNAEEAIQkgB0EANgIMIAcgCDYCCCAHQRA2AgQQaQJAQYABQQgQVyIKRQ0AIAdBADYCGCAHIAo2AhQgB0EQNgIQAkAgAkECdCILQQBIDQACQAJAIAsNAEEBIQwMAQsQaUEBIQkgC0EBEFciDEUNAQsgB0EANgIkIAcgDDYCICAHIAs2AhwgAyADoSIYIAK4IhljRQ0DIAT8AyENIAb8A0EBaiEOQQAhDEEBIQkgAyEGA0ACQAJAIAIgGPwDIgtJDQAgB0EoaiABIAtqIAIgC2sgBxAMAkAgBygCKCIPQYCAgIB4Rw0AIAYgA2INByAHKAIsIAcoAjAQYSELIABBgICAgHg2AgAgACALNgIEAkAgBygCHCILRQ0AIAcoAiAgC0EBEFILAkAgBygCECILRQ0AIAogC0EDdEEIEFILIAcoAgQiC0UNCCAHKAIIIAtBA3RBCBBSDAgLIAcoAjQhECAHKAIwIQsgBygCLCERAkAgCUF/aiAHKAIERw0AIAdBBGoQJyAHKAIIIQgLIAggDGogBjkDACAHIAk2AgwCQCAHKAIYIhIgBygCEEcNACAHQRBqECcLIAcoAhQiCiASQQN0aiAEOQMAIAcgEkEBaiITNgIYIAsgDiALIA5JGyALIAYgBWYiFBsiFSANQQAgBiADYRsiFk0NAQJAIBUgFmsiFSAHKAIcIAcoAiQiF2tNDQAgB0EcaiAXIBUQIiAHKAIkIRcLAkAgFUUNACAHKAIgIBdqIBEgFmogFfwKAAALIAcgFyAVajYCJAwBCyALIAIgAkGohsAAEBIACyAGIBC4oCEGIAQgCyAWa7igIQQCQCAUDQACQCAPRQ0AIBEgD0EBEFILIAxBCGohDCAJQQFqIQkgBiADoSIYIBljDQEMBQsLAkAgBygCBCAJRw0AIAdBBGoQJwsgBygCCCAMakEIaiAGOQMAIAcgCUEBajYCDAJAIBMgBygCEEcNACAHQRBqECcgBygCFCEKCyAKIBNBA3RqIAQ5AwAgByASQQJqNgIYIA9FDQMgESAPQQEQUgwDCyAJIAsQRQALQQhBgAEQRQALQQhBgAEQRQALIAAgBykCHDcCACAAIAcpAhA3AhggACAHKAIYNgIgIAcgBygCJDYCMCAHIAcpAgQ3AjQgACAHKQMwNwIIIAcgBygCDDYCPCAAIAcpAzg3AhALIAcQYiAHQdAAaiQAC/UGAQZ/AkACQAJAAkACQAJAAkACQCAAQXxqIgQoAgAiBUF4cSIGQQRBCCAFQQNxIgcbIAFqSQ0AIAFBJ2ohCAJAIAdFDQAgBiAISw0CCwJAAkAgAkEJSQ0AIAIgAxAPIgINAUEADwtBACECIANBzP97Sw0IQRAgA0ELakF4cSADQQtJGyEBIABBeGohCAJAIAcNACABQYACSQ0HIAhFDQcgBiABTQ0HIAYgAWtBgIAISw0HIAAPCyAIIAZqIQcCQAJAIAYgAU8NACAHQQAoApSdQEYNAQJAIAdBACgCkJ1ARg0AIAcoAgQiBUECcQ0JIAVBeHEiCSAGaiIFIAFJDQkgByAJEBACQCAFIAFrIgdBEEkNACAEIAEgBCgCAEEBcXJBAnI2AgAgCCABaiIBIAdBA3I2AgQgCCAFaiIFIAUoAgRBAXI2AgQgASAHEA0MCQsgBCAFIAQoAgBBAXFyQQJyNgIAIAggBWoiASABKAIEQQFyNgIEDAgLQQAoAoidQCAGaiIHIAFJDQgCQAJAIAcgAWsiBkEPSw0AIAQgBUEBcSAHckECcjYCACAIIAdqIgEgASgCBEEBcjYCBEEAIQZBACEBDAELIAQgASAFQQFxckECcjYCACAIIAFqIgEgBkEBcjYCBCAIIAdqIgcgBjYCACAHIAcoAgRBfnE2AgQLQQAgATYCkJ1AQQAgBjYCiJ1ADAcLIAYgAWsiBkEPTQ0GIAQgASAFQQFxckECcjYCACAIIAFqIgEgBkEDcjYCBCAHIAcoAgRBAXI2AgQgASAGEA0MBgtBACgCjJ1AIAZqIgcgAUsNBAwGCwJAIAMgASADIAFJGyIDRQ0AIAIgACAD/AoAAAsgBCgCACIDQXhxIgdBBEEIIANBA3EiAxsgAWpJDQIgA0UNBiAHIAhNDQZB3JXAAEEuQYyWwAAQRgALQZyVwABBLkHMlcAAEEYAC0HclcAAQS5BjJbAABBGAAtBnJXAAEEuQcyVwAAQRgALIAQgASAFQQFxckECcjYCACAIIAFqIgUgByABayIBQQFyNgIEQQAgATYCjJ1AQQAgBTYClJ1ACyAIRQ0AIAAPCyADEAIiAUUNAQJAIANBfEF4IAQoAgAiAkEDcRsgAkF4cWoiAiADIAJJGyIDRQ0AIAEgACAD/AoAAAsgASECCyAAEAgLIAILoAYBBH8gAEF4aiIBIABBfGooAgAiAkF4cSIAaiEDAkACQCACQQFxDQAgAkECcUUNASABKAIAIgIgAGohAAJAIAEgAmsiAUEAKAKQnUBHDQAgAygCBEEDcUEDRw0BQQAgADYCiJ1AIAMgAygCBEF+cTYCBCABIABBAXI2AgQgAyAANgIADwsgASACEBALAkACQAJAAkACQAJAAkACQCADKAIEIgJBAnENACADQQAoApSdQEYNAiADQQAoApCdQEYNAyADIAJBeHEiAhAQIAEgAiAAaiIAQQFyNgIEIAEgAGogADYCACABQQAoApCdQEcNAUEAIAA2AoidQA8LIAMgAkF+cTYCBCABIABBAXI2AgQgASAAaiAANgIACyAAQYACSQ0EIAEgABARQQBBACgCqJ1AQX9qIgE2AqidQCABDQZBACgC8JpAIgANAkH/HyEBDAMLQQAgATYClJ1AQQBBACgCjJ1AIABqIgA2AoydQCABIABBAXI2AgQCQCABQQAoApCdQEcNAEEAQQA2AoidQEEAQQA2ApCdQAsgAEEAKAKgnUAiAk0NBUEAKAKUnUAiAEUNBUEAKAKMnUAiBEEpSQ0EQeiawAAhAQNAAkAgASgCACIDIABLDQAgACADIAEoAgRqSQ0GCyABKAIIIQEMAAsLQQAgATYCkJ1AQQBBACgCiJ1AIABqIgA2AoidQCABIABBAXI2AgQgASAAaiAANgIADwtBACEBA0AgAUEBaiEBIAAoAggiAA0ACyABQf8fIAFB/x9LGyEBC0EAIAE2AqidQA8LAkACQEEAKAKAnUAiA0EBIABBA3Z0IgJxDQBBACADIAJyNgKAnUAgAEH4AXFB+JrAAGoiACEDDAELIABB+AFxIgBB+JrAAGohAyAAQYCbwABqKAIAIQALIAMgATYCCCAAIAE2AgwgASADNgIMIAEgADYCCA8LAkACQEEAKALwmkAiAA0AQf8fIQEMAQtBACEBA0AgAUEBaiEBIAAoAggiAA0ACyABQf8fIAFB/x9LGyEBC0EAIAE2AqidQCAEIAJNDQBBAEF/NgKgnUALC9wFAgh/AX5BK0GAgMQAIAAoAggiBkGAgIABcSIHGyEIIAdBFXZBASABGyAFaiEJAkACQCAGQYCAgARxDQBBACECDAELAkACQCADQRBJDQAgAiADEAUhBwwBCwJAIAMNAEEAIQcMAQsgA0EDcSEKQQAhC0EAIQcCQCADQQRJDQAgA0EMcSEMQQAhC0EAIQcDQCAHIAIgC2oiDSwAAEG/f0pqIA1BAWosAABBv39KaiANQQJqLAAAQb9/SmogDUEDaiwAAEG/f0pqIQcgDCALQQRqIgtHDQALIApFDQELIAIgC2ohDQNAIAcgDSwAAEG/f0pqIQcgDUEBaiENIApBf2oiCg0ACwsgByAJaiEJCyAIQS0gARshDAJAAkAgCSAALwEMIgFPDQACQAJAAkAgBkGAgIAIcQ0AIAEgCWshCEEAIQdBACEBAkACQAJAIAZBHXZBA3EOBAIAAQACCyAIIQEMAQsgCEH+/wNxQQF2IQELIAZB////AHEhCSAAKAIEIQsgACgCACEKA0AgB0H//wNxIAFB//8DcU8NAkEBIQ0gB0EBaiEHIAogCSALKAIQEQUARQ0ADAULCyAAIAApAggiDqdBgICA/3lxQbCAgIACcjYCCEEBIQ0gACgCACIKIAAoAgQiCyAMIAIgAxA1DQNBACEHIAEgCWtB//8DcSECA0AgB0H//wNxIAJPDQJBASENIAdBAWohByAKQTAgCygCEBEFAEUNAAwECwtBASENIAogCyAMIAIgAxA1DQIgCiAEIAUgCygCDBEHAA0CQQAhByAIIAFrQf//A3EhAANAIAdB//8DcSICIABJIQ0gAiAATw0DIAdBAWohByAKIAkgCygCEBEFAEUNAAwDCwtBASENIAogBCAFIAsoAgwRBwANASAAIA43AghBAA8LQQEhDSAAKAIAIgcgACgCBCIKIAwgAiADEDUNACAHIAQgBSAKKAIMEQcAIQ0LIA0L+gQBB38CQAJAIAAoAggiA0GAgIDAAXFFDQACQAJAAkACQAJAIANBgICAgAFxRQ0AIAAvAQ4iBA0BQQAhAgwCCwJAIAJBEEkNACABIAIQBSEFDAQLAkAgAg0AQQAhBQwECyACQQNxIQZBACEHQQAhBQJAIAJBBEkNACACQQxxIQRBACEFQQAhBwNAIAUgASAHaiIILAAAQb9/SmogCEEBaiwAAEG/f0pqIAhBAmosAABBv39KaiAIQQNqLAAAQb9/SmohBSAEIAdBBGoiB0cNAAsgBkUNBAsgASAHaiEIA0AgBSAILAAAQb9/SmohBSAIQQFqIQggBkF/aiIGDQAMBAsLIAEgAmohB0EAIQIgASEIIAQhBgNAIAgiBSAHRg0CAkACQCAFLAAAIghBf0wNACAFQQFqIQgMAQsCQCAIQWBPDQAgBUECaiEIDAELIAVBBEEDIAhBb0sbaiEICyAIIAVrIAJqIQIgBkF/aiIGDQALC0EAIQYLIAQgBmshBQsgBSAALwEMIghPDQAgCCAFayEJQQAhBUEAIQQCQAJAAkAgA0EddkEDcQ4EAgABAgILIAkhBAwBCyAJQf7/A3FBAXYhBAsgA0H///8AcSEHIAAoAgQhBiAAKAIAIQACQANAIAVB//8DcSAEQf//A3FPDQFBASEIIAVBAWohBSAAIAcgBigCEBEFAA0DDAALC0EBIQggACABIAIgBigCDBEHAA0BQQAhBSAJIARrQf//A3EhAgNAIAVB//8DcSIEIAJJIQggBCACTw0CIAVBAWohBSAAIAcgBigCEBEFAA0CDAALCyAAKAIAIAEgAiAAKAIEKAIMEQcAIQgLIAgLwAQBCH8jAEEQayIEJAACQAJAAkAgA0EBcQ0AIAItAAAiBQ0BQQAhBQwCCyAAIAIgA0EBdiABKAIMEQcAIQUMAQsgASgCDCEGQQAhBwNAIAJBAWohCAJAAkACQAJAAkAgBcBBf0oNACAFQf8BcSIJQYABRg0BIAlBwAFHDQMgBCABNgIEIAQgADYCACAEQqCAgIAGNwIIIAMgB0EDdGoiBSgCACAEIAUoAgQRBQBFDQJBASEFDAYLAkAgACAIIAVB/wFxIgUgBhEHAA0AIAggBWohAgwEC0EBIQUMBQsCQCAAIAJBA2oiBSACLwABIgIgBhEHAA0AIAUgAmohAgwDC0EBIQUMBAsgB0EBaiEHIAghAgwBC0GggICABiEKAkAgBUEBcUUNACACQQVqIQggAigAASEKC0EAIQkCQAJAIAVBAnENAEEAIQsgCCECDAELIAhBAmohAiAILwAAIQsLAkACQCAFQQRxDQAgAiEIDAELIAJBAmohCCACLwAAIQkLAkACQCAFQQhxDQAgCCECDAELIAhBAmohAiAILwAAIQcLAkAgBUEQcUUNACADIAtB//8DcUEDdGovAQQhCwsCQCAFQSBxRQ0AIAMgCUH//wNxQQN0ai8BBCEJCyAEIAk7AQ4gBCALOwEMIAQgCjYCCCAEIAE2AgQgBCAANgIAAkAgAyAHQQN0aiIFKAIAIAQgBSgCBBEFAEUNAEEBIQUMAwsgB0EBaiEHCyACLQAAIgUNAAtBACEFCyAEQRBqJAAgBQv4AwEGfyMAQRBrIgQkAAJAAkACQAJAAkACQAJAAkAgAkEaSQ0AIAEtAABBH0cNACABLQABQYsBRw0AIAEtAAJBCEcNACABLQADQQRHDQAgAS0ACkEGRw0AIAEtAAxBwgBHDQAgAS0ADUHDAEcNACACIAEvABAiBU0NACAFQRlJDQAgBUF9aiIGIAJPDQEgBUF+aiIHIAJPDQIgBUF/aiIIIAJPDQMgBSACTw0EIAVBeWoiCUESSQ0FIAkgAksNBSABIAdqLQAAQQh0IAEgBmotAAByIAEgCGotAABBEHRyIAEgBWotAABBGHQiCXIhAkEAIQYgCUEASA0GQQEhCQJAIAJFDQAQaUEBIQYgAkEBEFgiCUUNBwsgBEEIaiADIAFBEmogBUFnaiAJIAIQJgJAIAQtAAhBAUcNACAAQRQ2AgggAEGEhsAANgIEIABBgICAgHg2AgAgAkUNCCAJIAJBARBSDAgLIAAgBUEBajYCDCAAIAI2AgggACAJNgIEIAAgAjYCAAwHCyAAQRM2AgggAEG/gMAANgIEIABBgICAgHg2AgAMBgsgBiACQcSFwAAQLQALIAcgAkHUhcAAEC0ACyAIIAJB5IXAABAtAAsgBSACQfSFwAAQLQALQRIgCSACQZiGwAAQEgALIAYgAhBFAAsgBEEQaiQAC4UEAQJ/IAAgAWohAgJAAkAgACgCBCIDQQFxDQAgA0ECcUUNASAAKAIAIgMgAWohAQJAIAAgA2siAEEAKAKQnUBHDQAgAigCBEEDcUEDRw0BQQAgATYCiJ1AIAIgAigCBEF+cTYCBCAAIAFBAXI2AgQgAiABNgIADAILIAAgAxAQCwJAAkACQAJAIAIoAgQiA0ECcQ0AIAJBACgClJ1ARg0CIAJBACgCkJ1ARg0DIAIgA0F4cSIDEBAgACADIAFqIgFBAXI2AgQgACABaiABNgIAIABBACgCkJ1ARw0BQQAgATYCiJ1ADwsgAiADQX5xNgIEIAAgAUEBcjYCBCAAIAFqIAE2AgALAkAgAUGAAkkNACAAIAEQEQ8LAkACQEEAKAKAnUAiAkEBIAFBA3Z0IgNxDQBBACACIANyNgKAnUAgAUH4AXFB+JrAAGoiASECDAELIAFB+AFxIgFB+JrAAGohAiABQYCbwABqKAIAIQELIAIgADYCCCABIAA2AgwgACACNgIMIAAgATYCCA8LQQAgADYClJ1AQQBBACgCjJ1AIAFqIgE2AoydQCAAIAFBAXI2AgQgAEEAKAKQnUBHDQFBAEEANgKInUBBAEEANgKQnUAPC0EAIAA2ApCdQEEAQQAoAoidQCABaiIBNgKInUAgACABQQFyNgIEIAAgAWogATYCAA8LC8YDAQh/IwBBIGsiAyQAIAMQQDYCAEEAIQQCQCACQQJ0IgVBAEgNAAJAAkAgBQ0AQQEhBgwBCxBpQQEhBCAFQQEQVyIGRQ0BC0EAIQcgA0EANgIMIAMgBjYCCCADIAU2AgQCQAJAIAJFDQBBACEFA0AgA0EQaiABIAVqIAIgBWsgAxAMIAMoAhghBCADKAIUIQgCQCADKAIQIglBgICAgHhHDQACQCAEQRNHDQAgBUUNACAIKQAAQunc2YvGrZqyIIUgCEEIaikAAELizumzhoTasuEAhYQgCEELaikAAELmwKCrlozZsvIAhYRCAFENAwsgCCAEEGEhBSAAQYCAgIB4NgIAIAAgBTYCBCADKAIEIgVFDQMgAygCCCAFQQEQUgwDCyADKAIcIQoCQAJAAkAgBCADKAIEIAdrTQ0AIANBBGogByAEECIgAygCCCEGIAMoAgwhBwwBCyAERQ0BCyAERQ0AIAYgB2ogCCAE/AoAAAsgAyAHIARqIgc2AgwgCiAFaiEFAkAgCUUNACAIIAlBARBSCyAFIAJJDQALCyAAIAMoAgw2AgggACADKQIENwIACyADEGIgA0EgaiQADwsgBCAFEEUAC+8CAQV/QQAhAgJAIAFBzf97IABBECAAQRBLGyIAa08NACAAQRAgAUELakF4cSABQQtJGyIDakEMahACIgFFDQAgAUF4aiECAkACQCAAQX9qIgQgAXENACACIQAMAQsgAUF8aiIFKAIAIgZBeHEgBCABakEAIABrcUF4aiIBQQAgACABIAJrQRBLG2oiACACayIBayEEAkAgBkEDcUUNACAAIAQgACgCBEEBcXJBAnI2AgQgACAEaiIEIAQoAgRBAXI2AgQgBSABIAUoAgBBAXFyQQJyNgIAIAIgAWoiBCAEKAIEQQFyNgIEIAIgARANDAELIAIoAgAhAiAAIAQ2AgQgACACIAFqNgIACwJAIAAoAgQiAUEDcUUNACABQXhxIgIgA0EQak0NACAAIAMgAUEBcXJBAnI2AgQgACADaiIBIAIgA2siA0EDcjYCBCAAIAJqIgIgAigCBEEBcjYCBCABIAMQDQsgAEEIaiECCyACC4kDAQR/IAAoAgwhAgJAAkACQAJAIAFBgAJJDQAgACgCGCEDAkACQAJAIAIgAEcNACAAQRRBECAAKAIUIgIbaigCACIBDQFBACECDAILIAAoAggiASACNgIMIAIgATYCCAwBCyAAQRRqIABBEGogAhshBANAIAQhBSABIgJBFGogAkEQaiACKAIUIgEbIQQgAkEUQRAgARtqKAIAIgENAAsgBUEANgIACyADRQ0CAkACQCAAIAAoAhxBAnRB6JnAAGoiASgCAEYNACADKAIQIABGDQEgAyACNgIUIAINAwwECyABIAI2AgAgAkUNBAwCCyADIAI2AhAgAg0BDAILAkAgAiAAKAIIIgRGDQAgBCACNgIMIAIgBDYCCA8LQQBBACgCgJ1AQX4gAUEDdndxNgKAnUAPCyACIAM2AhgCQCAAKAIQIgFFDQAgAiABNgIQIAEgAjYCGAsgACgCFCIBRQ0AIAIgATYCFCABIAI2AhgPCw8LQQBBACgChJ1AQX4gACgCHHdxNgKEnUALxwIBBH9BACECAkAgAUEIdiIDRQ0AQR8hAiABQYCAgAhPDQAgAUEmIANnIgJrdkEBcSACQQF0ckE+cyECCyAAQgA3AhAgACACNgIcIAJBAnRB6JnAAGohAwJAQQAoAoSdQEEBIAJ0IgRxDQAgAyAANgIAIAAgAzYCGCAAIAA2AgwgACAANgIIQQBBACgChJ1AIARyNgKEnUAPCwJAAkACQCADKAIAIgQoAgRBeHEgAUcNACAEIQIMAQsgAUEAQRkgAkEBdmsgAkEfRht0IQMDQCAEIANBHXZBBHFqIgUoAhAiAkUNAiADQQF0IQMgAiEEIAIoAgRBeHEgAUcNAAsLIAIoAggiAyAANgIMIAIgADYCCCAAQQA2AhggACACNgIMIAAgAzYCCA8LIAVBEGogADYCACAAIAQ2AhggACAANgIMIAAgADYCCAulAgIBfwF+IwBBIGsiBCQAAkACQAJAIAAgAksNACABIAJLDQFBFq1CIIYhBSAAIAFNDQIgBCAANgIIIAQgATYCDCAEIAUgBEEMaq2ENwMYIAQgBSAEQQhqrYQ3AxBB0oDAACAEQRBqIAMQMQALIAQgADYCCCAEIAI2AgwgBEEWrUIghiIFIARBDGqthDcDGCAEIAUgBEEIaq2ENwMQQbGBwAAgBEEQaiADEDEACyAEIAE2AgggBCACNgIMIARBFq1CIIYiBSAEQQxqrYQ3AxggBCAFIARBCGqthDcDEEHqgcAAIARBEGogAxAxAAsgBCABNgIIIAQgAjYCDCAEIAUgBEEMaq2ENwMYIAQgBSAEQQhqrYQ3AxBB6oHAACAEQRBqIAMQMQALpwIBB38jAEEQayICJABBCiEDIAAoAgAiBCEFAkAgBEHoB0kNAEEKIQMgBCEFA0AgAkEGaiADaiIGQXxqIAUiACAAQZDOAG4iBUGQzgBsayIHQf//A3FB5ABuIghBAXQvAMSXQDsAACAGQX5qIAcgCEHkAGxrQf//A3FBAXQvAMSXQDsAACADQXxqIQMgAEH/rOIESw0ACwsCQAJAIAVBCUsNACAFIQAMAQsgAkEGaiADQX5qIgNqIAUgBUH//wNxQeQAbiIAQeQAbGtB//8DcUEBdC8AxJdAOwAACwJAAkAgBEUNACAARQ0BCyACQQZqIANBf2oiA2ogAEEBdC0AxZdAOgAACyABQQFBAUEAIAJBBmogA2pBCiADaxAJIQMgAkEQaiQAIAMLpQIBBn8gACgCCCECAkACQCABQYABTw0AQQEhAwwBCwJAIAFBgBBPDQBBAiEDDAELQQNBBCABQYCABEkbIQMLIAIhBAJAIAMgACgCACACa00NACAAIAIgA0EBQQEQISAAKAIIIQQLIAAoAgQgBGohBAJAAkAgAUGAAUkNACABQT9xQYB/ciEFIAFBBnYhBgJAIAFBgBBPDQAgBCAFOgABIAQgBkHAAXI6AAAMAgsgAUEMdiEHIAZBP3FBgH9yIQYCQCABQf//A0sNACAEIAU6AAIgBCAGOgABIAQgB0HgAXI6AAAMAgsgBCAFOgADIAQgBjoAAiAEIAdBP3FBgH9yOgABIAQgAUESdkFwcjoAAAwBCyAEIAE6AAALIAAgAyACajYCCEEAC4ICAQd/IwBBEGsiAiQAAkACQAJAAkAgAQ0AIABFDQEgAEF4aiIBKAIAQQFHDQIgACgCICEDIAAoAhwhBCAAKAIUIQUgACgCECEGIAAoAgghByAAKAIEIQggAUEANgIAAkAgAUF/Rg0AIABBfGoiACAAKAIAQX9qIgA2AgAgAA0AIAFBMEEEEFILAkAgCEUNACAHIAhBARBSCwJAIAZFDQAgBSAGQQN0QQgQUgsgBEUNAyADIARBA3RBCBBSDAMLIABFDQAgAEF4aiIAIAAoAgBBf2oiATYCACACIAA2AgwgAQ0CIAJBDGoQJAwCCxBZAAtBgIDAAEE/EFoACyACQRBqJAALjgIBA38jAEEgayIFJAACQAJAAkACQAJAAkACQAJAQQEQL0H/AXEOAwQBAAELQQAoAtiZQCIGQX9MDQMgBkEBaiIHIAZIDQRBACAHNgLYmUBBACgC3JlARQ0BIAVBCGogACABKAIUEQQAIAUgBDoAHSAFIAM6ABwgBSACNgIYIAUgBSkDCDcCEEEAKALcmUAgBUEQakEAKALgmUAoAhQRBAAMAgsgBSAAIAEoAhgRBAAAC0GAgICAeCAFEEELQQBBACgC2JlAIgVBf2o2AtiZQCAFQQBMDQJBAEEAOgDQmUAgAw0DCwALQZyWwABBHEG4lsAAEDIAC0HolsAAQc0AQZCXwAAQMQALIAAgARBTAAveAQEBfyMAQTBrIgckACAHQQxqIAEgAiADIAQgBSAGEAYCQCACRQ0AIAEgAkEBEFILAkACQAJAIAcoAgxBgICAgHhHDQBBASEBIAcoAhAhAgwBCxBpQTBBBBBXIgJFDQFBACEBIAJBADYCCCACQoGAgIAQNwIAIAIgBykCDDcCDCACIAcpAhQ3AhQgAiAHKQIcNwIcIAIgBykCJDcCJCACIAcoAiw2AiwgAkEIaiECCyAAIAE2AgggACACQQAgARs2AgQgAEEAIAIgARs2AgAgB0EwaiQADwtBBEEwEF4AC8wBAQN/IwBBEGsiAyQAIANBBGogASACEA4CQCACRQ0AIAEgAkEBEFILAkACQAJAIAMoAgQiBEGAgICAeEcNAEEBIQRBACEBIAMoAgghBUEAIQIMAQsgAygCCCEFAkACQCAEIAMoAgwiAksNACAFIQEMAQsCQCACDQBBASEBIAUgBEEBEFIMAQsgBSAEQQEgAhBNIgFFDQILQQAhBUEAIQQLIAAgBDYCDCAAIAU2AgggACACNgIEIAAgATYCACADQRBqJAAPC0EBIAIQRQAL6wECAn8BfiMAQTBrIgIkAAJAIAEoAgBBgICAgHhHDQAgASgCDCEDIAJBADYCLCACQoCAgIAQNwIkIAJBJGpBrJTAACADKAIAIgMoAgAgAygCBBALGiACIAIoAiwiAzYCICACIAIpAiQiBDcDGCABIAM2AgggASAENwIACyABKAIIIQMgAUEANgIIIAEpAgAhBCABQoCAgIAQNwIAIAIgAzYCECACIAQ3AwgQaQJAQQxBBBBXIgENAEEEQQwQXgALIAEgAigCEDYCCCABIAIpAwg3AgAgAEHYlsAANgIEIAAgATYCACACQTBqJAALuAEBBH8CQCACRQ0AIAJBA3EhA0EAIQQCQCACQQRJDQAgAkF8cSEFQQAhBANAIAAgBGoiAiABIARqIgYtAAA6AAAgAkEBaiAGQQFqLQAAOgAAIAJBAmogBkECai0AADoAACACQQNqIAZBA2otAAA6AAAgBSAEQQRqIgRHDQALCyADRQ0AIAEgBGohAiAAIARqIQQDQCAEIAItAAA6AAAgAkEBaiECIARBAWohBCADQX9qIgMNAAsLIAALxQEBBX8CQAJAAkACQCABRQ0AIAFBeGoiAiACKAIAIgNBAWoiBDYCACAERQ0BIAEoAgANAiABKAIYIQQgAUEANgIYIAEoAhQhBSABKAIQIQYgAUKAgICAgAE3AhAgAiADNgIAAkACQCAGIARLDQAgBSEBDAELIAZBA3QhAgJAIAQNAEEIIQEgBSACQQgQUgwBCyAFIAJBCCAEQQN0IgYQTSIBRQ0ECyAAIAQ2AgQgACABNgIADwsQWQsACxBbAAtBCCAGEEUAC8UBAQV/AkACQAJAAkAgAUUNACABQXhqIgIgAigCACIDQQFqIgQ2AgAgBEUNASABKAIADQIgASgCJCEEIAFBADYCJCABKAIgIQUgASgCHCEGIAFCgICAgIABNwIcIAIgAzYCAAJAAkAgBiAESw0AIAUhAQwBCyAGQQN0IQICQCAEDQBBCCEBIAUgAkEIEFIMAQsgBSACQQggBEEDdCIGEE0iAUUNBAsgACAENgIEIAAgATYCAA8LEFkLAAsQWwALQQggBhBFAAu1AQEDfwJAIAJFDQAgAkEHcSEDQQAhBAJAIAJBCEkNACACQXhxIQVBACEEA0AgACAEaiICIAE6AAAgAkEHaiABOgAAIAJBBmogAToAACACQQVqIAE6AAAgAkEEaiABOgAAIAJBA2ogAToAACACQQJqIAE6AAAgAkEBaiABOgAAIAUgBEEIaiIERw0ACwsgA0UNACAAIARqIQIDQCACIAE6AAAgAkEBaiECIANBf2oiAw0ACwsgAAu4AQEFfwJAAkACQAJAIAFFDQAgAUF4aiICIAIoAgAiA0EBaiIENgIAIARFDQEgASgCAA0CIAEoAgwhBCABQQA2AgwgASgCCCEFIAEoAgQhBiABQoCAgIAQNwIEIAIgAzYCAAJAAkAgBiAESw0AIAUhAQwBCwJAIAQNAEEBIQEgBSAGQQEQUgwBCyAFIAZBASAEEE0iAUUNBAsgACAENgIEIAAgATYCAA8LEFkLAAsQWwALQQEgBBBFAAuqAQICfwF+QQEhBkEEIQcCQAJAIAWtIAOtfiIIQiCIp0UNAEEAIQMMAQsCQCAIpyIDQYCAgIB4IARrTQ0AQQAhAwwBCwJAAkACQAJAIAFFDQAgAiAFIAFsIAQgAxBNIQcMAQsCQCADDQAgBCEHDAILEGkgAyAEEFchBwsgBw0AIAAgBDYCBAwBCyAAIAc2AgRBACEGC0EIIQcLIAAgB2ogAzYCACAAIAY2AgALqgECAn8BfkEBIQZBBCEHAkACQCAFrSADrX4iCEIgiKdFDQBBACEDDAELAkAgCKciA0GAgICAeCAEa00NAEEAIQMMAQsCQAJAAkACQCABRQ0AIAIgBSABbCAEIAMQTSEHDAELAkAgAw0AIAQhBwwCCxBpIAMgBBBXIQcLIAcNACAAIAQ2AgQMAQsgACAHNgIEQQAhBgtBCCEHCyAAIAdqIAM2AgAgACAGNgIAC5UBAQF/IwBBEGsiBSQAAkAgAiABaiIBIAJPDQBBAEEAEEUACyAFQQRqIAAoAgAiAiAAKAIEIAEgAkEBdCICIAEgAksbIgJBCEEEIARBAUYbIgEgAiABSxsiAiADIAQQIAJAIAUoAgRBAUcNACAFKAIIIAUoAgwQRQALIAUoAgghBCAAIAI2AgAgACAENgIEIAVBEGokAAuLAQEBfyMAQRBrIgMkAAJAIAIgAWoiASACTw0AQQBBABBFAAsgA0EEaiAAKAIAIgIgACgCBCABIAJBAXQiAiABIAJLGyICQQggAkEISxsiAkEBQQEQHwJAIAMoAgRBAUcNACADKAIIIAMoAgwQRQALIAMoAgghASAAIAI2AgAgACABNgIEIANBEGokAAuTAQICfwF+IwBBIGsiAiQAAkAgASgCAEGAgICAeEcNACABKAIMIQMgAkEANgIcIAJCgICAgBA3AhQgAkEUakGslMAAIAMoAgAiAygCACADKAIEEAsaIAIgAigCHCIDNgIQIAIgAikCFCIENwMIIAEgAzYCCCABIAQ3AgALIABB2JbAADYCBCAAIAE2AgAgAkEgaiQAC3wBAX8CQCAAKAIAIgAoAgwiAUUNACAAKAIQIAFBARBSCwJAIAAoAhgiAUUNACAAKAIcIAFBA3RBCBBSCwJAIAAoAiQiAUUNACAAKAIoIAFBA3RBCBBSCwJAIABBf0YNACAAIAAoAgRBf2oiATYCBCABDQAgAEEwQQQQUgsLiAEBA38jAEEQayIBJAACQCAAKAIAIgIoAgQiA0EBcUUNACACKAIAIQIgASADQQF2NgIEIAEgAjYCACABQcSUwAAgACgCBCAAKAIIIgAtAAggAC0ACRAWAAsgAUGAgICAeDYCACABIAA2AgwgAUHglMAAIAAoAgQgACgCCCIALQAIIAAtAAkQFgALhAEBAn8jAEEQayIGJABBACEHIAZBADYCDAJAAkACQAJAAkAgASgCACACIAMgBCAFIAZBDGoQSA4EAQIAAwALQcSHwABB7ABBsIjAABA3AAsgACAGKAIMNgIEDAILIABBADoAAUEBIQcMAQtBASEHIABBAToAAQsgACAHOgAAIAZBEGokAAtrAQN/IwBBEGsiASQAIAFBBGogACgCACICIAAoAgQgAkEBdCICQQQgAkEESxsiAkEIQQgQHwJAIAEoAgRBAUcNACABKAIIIAEoAgwQRQALIAEoAgghAyAAIAI2AgAgACADNgIEIAFBEGokAAtgAQJ/AkACQCACQRB2IAJB//8DcUEAR2oiAkAAIgNBf0cNAEEAIQJBACEEDAELIAJBEHQiBEFwaiAEIANBEHQiAkEAIARrRhshBAsgAEEANgIIIAAgBDYCBCAAIAI2AgALYAECfwJAAkAgAEF8aigCACIDQXhxIgRBBEEIIANBA3EiAxsgAWpJDQACQCADRQ0AIAQgAUEnaksNAgsgABAIDwtBnJXAAEEuQcyVwAAQRgALQdyVwABBLkGMlsAAEEYAC1oBAX8CQAJAAkAgAiAAKAIAIAAoAggiA2tNDQAgACADIAJBAUEBECEgACgCCCEDDAELIAJFDQELIAJFDQAgACgCBCADaiABIAL8CgAACyAAIAMgAmo2AghBAAtZAQJ/IAEoAgAhAiABQQA2AgACQAJAIAJFDQAgASgCBCEDEGlBCEEEEFciAUUNASABIAM2AgQgASACNgIAIABByJbAADYCBCAAIAE2AgAPCwALQQRBCBBeAAtdAQJ/QQAhAQJAIAAoAgBBDEcNAEEAIQFBrNoAIAAoAgQiAkEAKALEmUAgAhsRAwAiAkUNACACQQBBrNoAEB0iASAAKAIIIgBBACgCyJlAIAAbNgKoWiABIQELIAELTgIBfwF+IwBBIGsiAyQAIAMgATYCDCADIAA2AgggA0EWrUIghiIEIANBCGqthDcDGCADIAQgA0EMaq2ENwMQQfqAwAAgA0EQaiACEDEAC0UAAkACQCABQQlJDQAgASAAEA8hAQwBCyAAEAIhAQsCQCABRQ0AIAFBfGotAABBA3FFDQAgAEUNACABQQAgAPwLAAsgAQtSAQJ/QQAhAUEAQQAoAuSZQCICQQFqNgLkmUACQCACQQBIDQBBASEBQQAtANCZQA0AQQAgADoA0JlAQQBBACgCzJlAQQFqNgLMmUBBAiEBCyABC0cBAn8gASgCBCECIAEoAgAhAxBpAkBBCEEEEFciAQ0AQQRBCBBeAAsgASACNgIEIAEgAzYCACAAQciWwAA2AgQgACABNgIACzsBAX8jAEEgayIDJAAgAyABNgIQIAMgADYCDCADQQE7ARwgAyACNgIYIAMgA0EMajYCFCADQRRqEDkACzkBAX8jAEEQayIDJAAgAyABNgIEIAMgADYCACADQRitQiCGIAOthDcDCEGfgsAAIANBCGogAhAxAAs0AAJAIAFpQQFHDQAgAEGAgICAeCABa0sNAAJAIABFDQAQaSAAIAEQVyIBRQ0BCyABDwsAC0AAAkAgACgCAEGAgICAeEYNACABIAAoAgQgACgCCBBMDwsgASgCACABKAIEIAAoAgwoAgAiACgCACAAKAIEEAsLOQACQCACQYCAxABGDQAgACACIAEoAhARBQBFDQBBAQ8LAkAgAw0AQQAPCyAAIAMgBCABKAIMEQcACzUBAX8CQCAARQ0AAkAgASgCACICRQ0AIAAgAhECAAsgASgCBCICRQ0AIAAgAiABKAIIEFILCyoBAX8jAEEQayIDJAAgAyACNgIMIAMgATYCCCADIAA2AgQgA0EEahBjAAstAQF/IwBBEGsiASQAIAEgACkCADcCCCABQQhqQZCUwAAgACgCCEEBQQAQFgALLAIBfwF+IwBBEGsiASQAIAApAgAhAiABIAA2AgwgASACNwIEIAFBBGoQZQALIwEBfyMAQRBrIgIkACACIAE2AgwgAiAANgIIIAJBCGoQZAALIAACQCABKAIARQ0AIABByJbAADYCBCAAIAE2AgAPCwALHgEBfwJAIAAoAgAiAkUNACABIAIgACgCBBBMDwsACxsBAX8QaSAAQQRqQQQQVyIBIAA2AgAgAUEEagseAQF/AkAgACgCACIBQQFIDQAgACgCBCABQQEQUgsLHgAgACgCACAAKAIEQQAoAtSZQCIAQQMgABsRBAAACyMBAX8CQEGMicAAECwiAA0AQcCIwABBOkH8iMAAEDcACyAACx8AAkAgAEGAgICAeHJBgICAgHhGDQAgASAAQQEQUgsLHAEBfwJAIAAoAgAiAUUNACAAKAIEIAFBARBSCwsXAAJAIAFBCUkNACABIAAQDw8LIAAQAgsVACAAQXxqIgAgACgCAEEEakEEEFILFAACQCAARQ0AIAAgARBeAAsQVQALEQAgACABQQF0QQFyIAIQMQALEgACQCABRQ0AIAAgASACEFILCxIAIAAgASACIAMgBEEAIAUQAwsVAAJAIABFDQAgACAAKAKoWhECAAsLGgAgAEEAKQKUlUA3AgggAEEAKQKMlUA3AgALGgAgAEEAKQKElUA3AgggAEEAKQL8lEA3AgALFgAgACgCACABIAIgACgCBCgCDBEHAAsNACAAIAEgAiADEAcPCxQAQQAgADYCrJlAQQBBATYCqJlACxMAIABByJbAADYCBCAAIAE2AgALEAAgASAAKAIAIAAoAgQQTAsQACABIAAoAgAgACgCBBAKCwsAIAAgASACECkPCwoAIAAgARBoGgALDwAgAEGslMAAIAEgAhALCxEAQaCXwABBI0G0l8AAEDEACwsAIAAjAGokACMACwkAIAAgARBDDwsJACAAIAEQLg8LDABBuIbAAEEbEFoACwkAIAAgARBgAAsNAEHThsAAQc8AEFoACwkAIAEgABA6AAsMACAAIAEpAgA3AwALCQAgASAAEFwACw0AIAFBjJnAAEEYEAoLCAAgACABEAALCAAgACABEAELCQAgACgCABBJCwcAIAAQOAALBwAgABA/AAsHACAAECUACwsAQQBBAToArJ1ACwkAIABBADYCAAsFABBqAAsDAA8LAwAACwu6GQIAQYCAwAALpBlhdHRlbXB0ZWQgdG8gdGFrZSBvd25lcnNoaXAgb2YgUnVzdCB2YWx1ZSB3aGlsZSBpdCB3YXMgYm9ycm93ZWRpbnZhbGlkIGJnemYgaGVhZGVyFnNsaWNlIGluZGV4IHN0YXJ0cyBhdCDADSBidXQgZW5kcyBhdCDAACBpbmRleCBvdXQgb2YgYm91bmRzOiB0aGUgbGVuIGlzIMASIGJ1dCB0aGUgaW5kZXggaXMgwAAScmFuZ2Ugc3RhcnQgaW5kZXggwCIgb3V0IG9mIHJhbmdlIGZvciBzbGljZSBvZiBsZW5ndGggwAAQcmFuZ2UgZW5kIGluZGV4IMAiIG91dCBvZiByYW5nZSBmb3Igc2xpY2Ugb2YgbGVuZ3RoIMAAL3J1c3RjL2FjNjhmYWEyMGM1OGNiY2NkMDFlZTcyMDhiZjNiNmU5M2E3ZDdmOTYvbGlicmFyeS9zdGQvc3JjL3N5cy9zeW5jL3J3bG9jay9ub190aHJlYWRzLnJzAC9ob21lL3J1bm5lci8uY2FyZ28vcmVnaXN0cnkvc3JjL2luZGV4LmNyYXRlcy5pby0xOTQ5Y2Y4YzZiNWI1NTdmL3dhc20tYmluZGdlbi0wLjIuMTIyL3NyYy9leHRlcm5yZWYucnMAL3J1c3RjL2FjNjhmYWEyMGM1OGNiY2NkMDFlZTcyMDhiZjNiNmU5M2E3ZDdmOTYvbGlicmFyeS9hbGxvYy9zcmMvcmF3X3ZlYy9tb2QucnMAL3J1c3QvZGVwcy9kbG1hbGxvYy0wLjIuMTEvc3JjL2RsbWFsbG9jLnJzAC9ob21lL3J1bm5lci8uY2FyZ28vcmVnaXN0cnkvc3JjL2luZGV4LmNyYXRlcy5pby0xOTQ5Y2Y4YzZiNWI1NTdmL2xpYmRlZmxhdGVyLTEuMjUuMi9zcmMvbGliLnJzAAC4AhAACgAAACkAAAAJAAAAuAIQAAoAAAAqAAAACQAAALgCEAAKAAAAKwAAAAkAAAC4AhAACgAAACwAAAAJAAAAZGVjb21wcmVzc2lvbiBmYWlsZWS4AhAACgAAAC8AAAAeAAAAuAIQAAoAAACGAAAAHwAAAG51bGwgcG9pbnRlciBwYXNzZWQgdG8gcnVzdHJlY3Vyc2l2ZSB1c2Ugb2YgYW4gb2JqZWN0IGRldGVjdGVkIHdoaWNoIHdvdWxkIGxlYWQgdG8gdW5zYWZlIGFsaWFzaW5nIGluIHJ1c3QAAH8BEABnAAAAhAAAABEAAAB/ARAAZwAAAJIAAAARAAAAbGliZGVmbGF0ZV9kZWZsYXRlX2RlY29tcHJlc3MgcmV0dXJuZWQgYW4gdW5rbm93biBlcnJvciB0eXBlOiB0aGlzIGlzIGFuIGludGVybmFsIGJ1ZyB0aGF0ICoqbXVzdCoqIGJlIGZpeGVkYwIQAF8AAAANAQAAFQAAAGxpYmRlZmxhdGVfYWxsb2NfZGVjb21wcmVzc29yIHJldHVybmVkIE5VTEw6IG91dCBvZiBtZW1vcnkAAGMCEABfAAAAnQAAABEAAAAMAAAAAQAAAAIAAAAAAAAAAAAAABAREgAIBwkGCgULBAwDDQIOAQ8AAAAAAAAAAAAAAAAAAAAAAAAAAQAAAAIAAAADAAAABAAAAAUAAAAGAAAABwAAAAgAAAAJAAAACgAAAAsAAAAMAAAADQAAAA4AAAAPAAAAEAAAABEAAAASAAAAAAAAAAEAAAACAAAAAwAAAAQAAQAFAAEABwACAAkAAgANAAMAEQADABkABAAhAAQAMQAFAEEABQBhAAYAgQAGAMEABwABAQcAgQEIAAECCAABAwkAAQQJAAEGCgABCAoAAQwLAAEQCwABGAwAASAMAAEwDQABQA0AAWANAAFgDQABYAAAAIAAAAGAAAACgAAAA4AAAASAAAAFgAAABoAAAAeAAAAIgAAACYAAAAqAAAALgAAADIAAAA2AAAAOgAAAD4AAABCAAAARgAAAEoAAABOAAAAUgAAAFYAAABaAAAAXgAAAGIAAABmAAAAagAAAG4AAAByAAAAdgAAAHoAAAB+AAAAggAAAIYAAACKAAAAjgAAAJIAAACWAAAAmgAAAJ4AAACiAAAApgAAAKoAAACuAAAAsgAAALYAAAC6AAAAvgAAAMIAAADGAAAAygAAAM4AAADSAAAA1gAAANoAAADeAAAA4gAAAOYAAADqAAAA7gAAAPIAAAD2AAAA+gAAAP4AAAECAAABBgAAAQoAAAEOAAABEgAAARYAAAEaAAABHgAAASIAAAEmAAABKgAAAS4AAAEyAAABNgAAAToAAAE+AAABQgAAAUYAAAFKAAABTgAAAVIAAAFWAAABWgAAAV4AAAFiAAABZgAAAWoAAAFuAAABcgAAAXYAAAF6AAABfgAAAYIAAAGGAAABigAAAY4AAAGSAAABlgAAAZoAAAGeAAABogAAAaYAAAGqAAABrgAAAbIAAAG2AAABugAAAb4AAAHCAAABxgAAAcoAAAHOAAAB0gAAAdYAAAHaAAAB3gAAAeIAAAHmAAAB6gAAAe4AAAHyAAAB9gAAAfoAAAH+AAACAgAAAgYAAAIKAAACDgAAAhIAAAIWAAACGgAAAh4AAAIiAAACJgAAAioAAAIuAAACMgAAAjYAAAI6AAACPgAAAkIAAAJGAAACSgAAAk4AAAJSAAACVgAAAloAAAJeAAACYgAAAmYAAAJqAAACbgAAAnIAAAJ2AAACegAAAn4AAAKCAAAChgAAAooAAAKOAAACkgAAApYAAAKaAAACngAAAqIAAAKmAAACqgAAAq4AAAKyAAACtgAAAroAAAK+AAACwgAAAsYAAALKAAACzgAAAtIAAALWAAAC2gAAAt4AAALiAAAC5gAAAuoAAALuAAAC8gAAAvYAAAL6AAAC/gAAAwIAAAMGAAADCgAAAw4AAAMSAAADFgAAAxoAAAMeAAADIgAAAyYAAAMqAAADLgAAAzIAAAM2AAADOgAAAz4AAANCAAADRgAAA0oAAANOAAADUgAAA1YAAANaAAADXgAAA2IAAANmAAADagAAA24AAANyAAADdgAAA3oAAAN+AAADggAAA4YAAAOKAAADjgAAA5IAAAOWAAADmgAAA54AAAOiAAADpgAAA6oAAAOuAAADsgAAA7YAAAO6AAADvgAAA8IAAAPGAAADygAAA84AAAPSAAAD1gAAA9oAAAPeAAAD4gAAA+YAAAPqAAAD7gAAA/IAAAP2AAAD+gAAA/4AAoAAAAAADAAAABAAAAAUAAAAGAAAABwAAAAgAAAAJAAAACgABAAsAAQANAAEADwABABEAAgATAAIAFwACABsAAgAfAAMAIwADACsAAwAzAAMAOwAEAEMABABTAAQAYwAEAHMABQCDAAUAowAFAMMABQDjAAAAAgEAAAIBAAACAQAAAAAIAAAABAAAAAQAAAAFAAAABgAAAAcAAAAIAAAADAAAAAQAAAAJAAAACgAAAAsAAAAAAAAACAAAAAQAAAAMAAAADQAAAA4AAAAPAAAAEAAAABAAAAAEAAAAEQAAABIAAAATAAAABwAAAG1dy9YsUOtjeEGmV3Ebi7krgVsBvYZR7Ay0wpzkyccEYXNzZXJ0aW9uIGZhaWxlZDogcHNpemUgPj0gc2l6ZSArIG1pbl9vdmVyaGVhZAAAOAIQACoAAACxBAAACQAAAGFzc2VydGlvbiBmYWlsZWQ6IHBzaXplIDw9IHNpemUgKyBtYXhfb3ZlcmhlYWQAADgCEAAqAAAAtwQAAA0AAAByd2xvY2sgb3ZlcmZsb3dlZCByZWFkIGxvY2tzIQEQAF0AAAAVAAAALAAAAAAAAAAIAAAABAAAABQAAAAIAAAADAAAAAQAAAAVAAAAcndsb2NrIGhhcyBub3QgYmVlbiBsb2NrZWQgZm9yIHJlYWRpbmcAACEBEABdAAAAPgAAAAkAAABjYXBhY2l0eSBvdmVyZmxvdwAAAOcBEABQAAAAHAAAAAUAAAAwMDAxMDIwMzA0MDUwNjA3MDgwOTEwMTExMjEzMTQxNTE2MTcxODE5MjAyMTIyMjMyNDI1MjYyNzI4MjkzMDMxMzIzMzM0MzUzNjM3MzgzOTQwNDE0MjQzNDQ0NTQ2NDc0ODQ5NTA1MTUyNTM1NDU1NTY1NzU4NTk2MDYxNjI2MzY0NjU2NjY3Njg2OTcwNzE3MjczNzQ3NTc2Nzc3ODc5ODA4MTgyODM4NDg1ODY4Nzg4ODk5MDkxOTI5Mzk0OTU5Njk3OTg5OVJlZkNlbGwgYWxyZWFkeSBib3Jyb3dlZABBpJnAAAsEBAAAAAApBG5hbWUBIgFWH19fd2JpbmRnZW5fYWRkX3RvX3N0YWNrX3BvaW50ZXIAPAlwcm9kdWNlcnMBDHByb2Nlc3NlZC1ieQIGd2FscnVzBjAuMjYuNAx3YXNtLWJpbmRnZW4HMC4yLjEyMg==",na=class e{static __wrap(t){let r=Object.create(e.prototype);return r.__wbg_ptr=t,Zv.register(r,r.__wbg_ptr,r),r}__destroy_into_raw(){let t=this.__wbg_ptr;return this.__wbg_ptr=0,Zv.unregister(this),t}free(){let t=this.__destroy_into_raw();xe.__wbg_chunksliceresult_free(t,0)}take_buffer(){try{let o=xe.__wbindgen_add_to_stack_pointer(-16);xe.chunksliceresult_take_buffer(o,this.__wbg_ptr);var t=lr().getInt32(o+0,!0),r=lr().getInt32(o+4,!0),n=rB(t,r).slice();return xe.__wbindgen_export(t,r*1,1),n}finally{xe.__wbindgen_add_to_stack_pointer(16)}}take_cpositions(){try{let o=xe.__wbindgen_add_to_stack_pointer(-16);xe.chunksliceresult_take_cpositions(o,this.__wbg_ptr);var t=lr().getInt32(o+0,!0),r=lr().getInt32(o+4,!0),n=eB(t,r).slice();return xe.__wbindgen_export(t,r*8,8),n}finally{xe.__wbindgen_add_to_stack_pointer(16)}}take_dpositions(){try{let o=xe.__wbindgen_add_to_stack_pointer(-16);xe.chunksliceresult_take_dpositions(o,this.__wbg_ptr);var t=lr().getInt32(o+0,!0),r=lr().getInt32(o+4,!0),n=eB(t,r).slice();return xe.__wbindgen_export(t,r*8,8),n}finally{xe.__wbindgen_add_to_stack_pointer(16)}}};Symbol.dispose&&(na.prototype[Symbol.dispose]=na.prototype.free);Zv=typeof FinalizationRegistry>"u"?{register:()=>{},unregister:()=>{}}:new FinalizationRegistry(e=>xe.__wbg_chunksliceresult_free(e,1));ra=null;Of=null;Gf=null;Xn=new Array(1024).fill(void 0);Xn.push(void 0,null,!0,!1);zc=Xn.length;Uf=new TextDecoder("utf-8",{ignoreBOM:!0,fatal:!0});Uf.decode();V8=2146435072,ih=0;lh=0;qc=null,sh=null});function W8(e){return e[0]===31&&e[1]===139}function lB(e){return e instanceof Error?e.message:`${e}`}async function Y8(e){if(typeof DecompressionStream<"u"){let t=new Blob([e]).stream().pipeThrough(new DecompressionStream("gzip"));return new Uint8Array(await new Response(t).arrayBuffer())}else return zv(e,void 0)}function q8(e){return lB(e).includes("invalid gzip header")?new Error("problem decompressing block: incorrect gzip header check",{cause:e}):e}async function Hf(e){try{return await aB(e)}catch(t){if(lB(t).includes("invalid bgzf header")){if(W8(e))return Y8(e);throw new Error("problem decompressing block: not a valid bgzf or gzip block",{cause:t})}throw q8(t)}}var uh=m(()=>{Xv();cB()});function uB(e){let t=0;for(let o of e)t+=o.length;let r=new Uint8Array(t),n=0;for(let o of e)r.set(o,n),n+=o.length;return r}var fB=m(()=>{});function K8(e){let t=0,r=[],n=()=>{t--,r.shift()?.()};return async o=>{t>=e&&await new Promise(i=>{r.push(i)}),t++;try{return await o()}finally{n()}}}function X8(e,t,r,n){let o=Math.max(0,r-t),i=Math.min(n,t+e.length)-t;return o<e.length?e.subarray(o,i):new Uint8Array(0)}var z8,J8,oa,dB=m(()=>{W1();uh();fB();z8=10,J8=65536;oa=class{filehandle;gzi;limit;constructor({filehandle:t,gziFilehandle:r,blockConcurrency:n=z8}){this.filehandle=t,this.gzi=new Uc({filehandle:r}),this.limit=K8(n)}async _readAndUncompressBlock(t,r){let n=await this.filehandle.read(r,t);return Hf(n)}async read(t,r){let{blocks:n,nextCompressedPosition:o}=await this.gzi.getRelevantBlocksForRead(t,r);if(n.length===0)return new Uint8Array(0);let i=r+t,s=await Promise.all(n.map(([a,c],l)=>this.limit(async()=>{let u=n[l+1]?.[0]??o??a+J8,d=await this._readAndUncompressBlock(a,u-a);return X8(d,c,r,i)})));return uB(s)}}});var fh=m(()=>{dB();uh()});var Vf=K((pne,AB)=>{AB.exports=JBrowseExports["react-dom"]});var pB=K((gne,mB)=>{mB.exports=JBrowseExports["react-dom/client"]});function gB(e){let t="",r=!1;for(let n=0,o=e.length;n<o;n++){let i=e[n];i==="<"?r=!0:i===">"?r=!1:r||(t+=i)}return t}var dh=m(()=>{});var hB=m(()=>{});var yB=m(()=>{});var xB=m(()=>{});function jf(e){return typeof e=="object"&&e!==null&&"uri"in e&&!!e.uri}var Z8,Ah=m(()=>{Z8=p(Kt(),1);xB()});var e6,CB=m(()=>{e6=p(Ps(),1)});var bB=m(()=>{});var EB=m(()=>{});var ia,$f,mh,ph,t6,Jc,Wf,wB=m(()=>{ia={METHOD:"method",PROPERTY:"property"},$f=class{constructor(t,r){this.inst=t,this.args=r}},mh=class extends $f{constructor(t,r){super(t,r),this.type=ia.METHOD}execute(t){t[this.inst](...this.args)}},ph=class extends $f{constructor(t,r){super(t,r),this.type=ia.PROPERTY}execute(t){t[this.inst]=this.args[0]}},t6={[ia.METHOD]:mh,[ia.PROPERTY]:ph},Jc=class{constructor(t,r,n){return new t6[t](r,n)}};Jc.METHOD=ia.METHOD;Jc.PROPERTY=ia.PROPERTY;Wf=Jc});var IB,wn,Yf,gh=m(()=>{wB();IB=Object.freeze({METHODS:["addHitRegion","arc","arcTo","beginPath","bezierCurveTo","clearHitRegions","clearRect","clip","closePath","drawFocusIfNeeded","drawImage","ellipse","fill","fillRect","fillText","lineTo","moveTo","putImageData","quadraticCurveTo","rect","removeHitRegion","resetTransform","restore","rotate","save","scale","scrollPathIntoView","setLineDash","setTransform","stroke","strokeRect","strokeText","transform","translate"],PROPERTIES:["direction","fillStyle","filter","font","globalAlpha","globalCompositeOperation","imageSmoothingEnabled","imageSmoothingQuality","lineCap","lineDashOffset","lineJoin","lineWidth","miterLimit","shadowBlur","shadowColor","shadowOffsetX","shadowOffsetY","strokeStyle","textAlign","textBaseline"]}),wn=Object.freeze({sequence:Symbol.for("sequence"),push:Symbol.for("push"),fromJSON:Symbol.for("fromJSON")}),Yf=class{constructor(t=null){this[wn.sequence]=[],t&&this[wn.fromJSON](t)}[wn.fromJSON](t={sequence:[]}){t.sequence.forEach(({type:r,inst:n,args:o})=>{this[wn.push](r,n,o)})}[wn.push](t,r,n){this[wn.sequence].push(new Wf(t,r,n))}execute(t){t.save(),this[wn.sequence].forEach(r=>r.execute(t)),t.restore()}toJSON(){return{sequence:this[wn.sequence]}}};IB.METHODS.forEach(e=>{Object.defineProperty(Yf.prototype,e,{value:function(...r){this[wn.push](Wf.METHOD,e,r)},writable:!1,enumerable:!0,configurable:!1})});IB.PROPERTIES.forEach(e=>{Object.defineProperty(Yf.prototype,e,{get(){throw`Invalid canvas sequencer interaction, cannot get ${e}.`},set(t){this[wn.push](Wf.PROPERTY,e,[t])},enumerable:!0,configurable:!1})})});var Mne,vB=m(()=>{gh();Mne=Object.freeze({sequence:Symbol.for("sequence"),push:Symbol.for("push")})});var BB=m(()=>{vB();gh()});var MB=K((Nne,TB)=>{TB.exports=!1});var r6,RB=m(()=>{BB();r6=p(MB(),1)});var n6,o6,QB=m(()=>{n6=p(O(),1),o6=p(Q(),1)});var _B=m(()=>{});var Gne,Une,Hne,Vne,kB=m(()=>{Gne=new Uint8Array([99,124,119,123,242,107,111,197,48,1,103,43,254,215,171,118,202,130,201,125,250,89,71,240,173,212,162,175,156,164,114,192,183,253,147,38,54,63,247,204,52,165,229,241,113,216,49,21,4,199,35,195,24,150,5,154,7,18,128,226,235,39,178,117,9,131,44,26,27,110,90,160,82,59,214,179,41,227,47,132,83,209,0,237,32,252,177,91,106,203,190,57,74,76,88,207,208,239,170,251,67,77,51,133,69,249,2,127,80,60,159,168,81,163,64,143,146,157,56,245,188,182,218,33,16,255,243,210,205,12,19,236,95,151,68,23,196,167,126,61,100,93,25,115,96,129,79,220,34,42,144,136,70,238,184,20,222,94,11,219,224,50,58,10,73,6,36,92,194,211,172,98,145,149,228,121,231,200,55,109,141,213,78,169,108,86,244,234,101,122,174,8,186,120,37,46,28,166,180,198,232,221,116,31,75,189,139,138,112,62,181,102,72,3,246,14,97,53,87,185,134,193,29,158,225,248,152,17,105,217,142,148,155,30,135,233,206,85,40,223,140,161,137,13,191,230,66,104,65,153,45,15,176,84,187,22]),Une=new Uint8Array([82,9,106,213,48,54,165,56,191,64,163,158,129,243,215,251,124,227,57,130,155,47,255,135,52,142,67,68,196,222,233,203,84,123,148,50,166,194,35,61,238,76,149,11,66,250,195,78,8,46,161,102,40,217,36,178,118,91,162,73,109,139,209,37,114,248,246,100,134,104,152,22,212,164,92,204,93,101,182,146,108,112,72,80,253,237,185,218,94,21,70,87,167,141,157,132,144,216,171,0,140,188,211,10,247,228,88,5,184,179,69,6,208,44,30,143,202,63,15,2,193,175,189,3,1,19,138,107,58,145,17,65,79,103,220,234,151,242,207,206,240,180,230,115,150,172,116,34,231,173,53,133,226,249,55,232,28,117,223,110,71,241,26,113,29,41,197,137,111,183,98,14,170,24,190,27,252,86,62,75,198,210,121,32,154,219,192,254,120,205,90,244,31,221,168,51,136,7,199,49,177,18,16,89,39,128,236,95,96,81,127,169,25,181,74,13,45,229,122,159,147,201,156,239,160,224,59,77,174,42,245,176,200,235,187,60,131,83,153,97,23,43,4,126,186,119,214,38,225,105,20,99,85,33,12,125]),Hne=new Uint8Array([1,2,4,8,16,32,64,128,27,54]),Vne=new Uint32Array([1116352408,1899447441,3049323471,3921009573,961987163,1508970993,2453635748,2870763221,3624381080,310598401,607225278,1426881987,1925078388,2162078206,2614888103,3248222580,3835390401,4022224774,264347078,604807628,770255983,1249150122,1555081692,1996064986,2554220882,2821834349,2952996808,3210313671,3336571891,3584528711,113926993,338241895,666307205,773529912,1294757372,1396182291,1695183700,1986661051,2177026350,2456956037,2730485921,2820302411,3259730800,3345764771,3516065817,3600352804,4094571909,275423344,430227734,506948616,659060556,883997877,958139571,1322822218,1537002063,1747873779,1955562222,2024104815,2227730452,2361852424,2428436474,2756734187,3204031479,3329325298])});function Kc(e,t){if(typeof t!="function"&&t!==null)throw new TypeError("Class extends value "+String(t)+" is not a constructor or null");hh(e,t);function r(){this.constructor=e}e.prototype=t===null?Object.create(t):(r.prototype=t.prototype,new r)}function yh(e){var t=typeof Symbol=="function"&&Symbol.iterator,r=t&&e[t],n=0;if(r)return r.call(e);if(e&&typeof e.length=="number")return{next:function(){return e&&n>=e.length&&(e=void 0),{value:e&&e[n++],done:!e}}};throw new TypeError(t?"Object is not iterable.":"Symbol.iterator is not defined.")}function sa(e,t){var r=typeof Symbol=="function"&&e[Symbol.iterator];if(!r)return e;var n=r.call(e),o,i=[],s;try{for(;(t===void 0||t-- >0)&&!(o=n.next()).done;)i.push(o.value)}catch(a){s={error:a}}finally{try{o&&!o.done&&(r=n.return)&&r.call(n)}finally{if(s)throw s.error}}return i}function aa(e,t,r){if(r||arguments.length===2)for(var n=0,o=t.length,i;n<o;n++)(i||!(n in t))&&(i||(i=Array.prototype.slice.call(t,0,n)),i[n]=t[n]);return e.concat(i||Array.prototype.slice.call(t))}var hh,Xc=m(()=>{hh=function(e,t){return hh=Object.setPrototypeOf||{__proto__:[]}instanceof Array&&function(r,n){r.__proto__=n}||function(r,n){for(var o in n)Object.prototype.hasOwnProperty.call(n,o)&&(r[o]=n[o])},hh(e,t)}});function In(e){return typeof e=="function"}var qf=m(()=>{});function zf(e){var t=function(n){Error.call(n),n.stack=new Error().stack},r=e(t);return r.prototype=Object.create(Error.prototype),r.prototype.constructor=r,r}var xh=m(()=>{});var Jf,DB=m(()=>{xh();Jf=zf(function(e){return function(r){e(this),this.message=r?r.length+` errors occurred during unsubscription:
+      `} 1.2s infinite ease-in-out`}}})});var Vv=X((Ure,Hv)=>{Hv.exports=function(){var e=document.getSelection();if(!e.rangeCount)return function(){};for(var t=document.activeElement,r=[],n=0;n<e.rangeCount;n++)r.push(e.getRangeAt(n));switch(t.tagName.toUpperCase()){case"INPUT":case"TEXTAREA":t.blur();break;default:t=null;break}return e.removeAllRanges(),function(){e.type==="Caret"&&e.removeAllRanges(),e.rangeCount||r.forEach(function(o){e.addRange(o)}),t&&t.focus()}}});var Wv=X((Hre,$v)=>{"use strict";var d8=Vv(),jv={"text/plain":"Text","text/html":"Url",default:"Text"},A8="Copy to clipboard: #{key}, Enter";function m8(e){var t=(/mac os x/i.test(navigator.userAgent)?"\u2318":"Ctrl")+"+C";return e.replace(/#{\s*key\s*}/g,t)}function p8(e,t){var r,n,o,i,s,a,c=!1;t||(t={}),r=t.debug||!1;try{o=d8(),i=document.createRange(),s=document.getSelection(),a=document.createElement("span"),a.textContent=e,a.ariaHidden="true",a.style.all="unset",a.style.position="fixed",a.style.top=0,a.style.clip="rect(0, 0, 0, 0)",a.style.whiteSpace="pre",a.style.webkitUserSelect="text",a.style.MozUserSelect="text",a.style.msUserSelect="text",a.style.userSelect="text",a.addEventListener("copy",function(u){if(u.stopPropagation(),t.format)if(u.preventDefault(),typeof u.clipboardData>"u"){r&&console.warn("unable to use e.clipboardData"),r&&console.warn("trying IE specific stuff"),window.clipboardData.clearData();var d=jv[t.format]||jv.default;window.clipboardData.setData(d,e)}else u.clipboardData.clearData(),u.clipboardData.setData(t.format,e);t.onCopy&&(u.preventDefault(),t.onCopy(u.clipboardData))}),document.body.appendChild(a),i.selectNodeContents(a),s.addRange(i);var l=document.execCommand("copy");if(!l)throw new Error("copy command was unsuccessful");c=!0}catch(u){r&&console.error("unable to copy using execCommand: ",u),r&&console.warn("trying IE specific stuff");try{window.clipboardData.setData(t.format||"text",e),t.onCopy&&t.onCopy(window.clipboardData),c=!0}catch(d){r&&console.error("unable to copy using clipboardData: ",d),r&&console.error("falling back to prompt"),n=m8("message"in t?t.message:A8),window.prompt(n,e)}}finally{s&&(typeof s.removeRange=="function"?s.removeRange(i):s.removeAllRanges()),a&&document.body.removeChild(a),o()}return c}$v.exports=p8});var Kv={};Bt(Kv,{default:()=>Jv});async function zv(e){let t=await fetch(e);if(!t.ok)throw new Error(`HTTP ${t.status} fetching ${e}: ${await t.text()}`);return t.text()}async function g8(e){return JSON.parse(await zv(e))}async function x8(e){if(Yg[e])return Yg[e];let t=new URL(e).search,r=await zv(e),n=h8.exec(r)?.[1]??"",o=await g8(new URL(n,e).href+t),i=new qv.SourceMapConsumer(o);return Yg[e]=i,i}async function C8(e){let t=[];for(let r of e.split(`
+`)){let n=y8.exec(r);if(!n){t.push(r);continue}let o=n[2],s=(await x8(o)).originalPositionFor({line:+n[3],column:+n[4]});if(!s.source||!s.line||!s.column){t.push(r);continue}t.push(`${s.source}:${s.line}:${s.column+1} (${n[1].trim()})`)}return t.join(`
+`)}function E8(e,t){return e.startsWith("Error:")?e.slice(`${t}`.length):e}function b8(e){return typeof e=="object"&&e!==null&&"stack"in e?`${e.stack}`:""}function Jv({error:e,onClose:t,extra:r}){let[n,o]=(0,Ks.useState)(),[i,s]=(0,Ks.useState)(),[a,c]=(0,Ks.useState)(!1),l=e?`${e}`:"",u=E8(b8(e),l);(0,Ks.useEffect)(()=>{(async()=>{try{o(await C8(u))}catch(f){console.error(f),o(u),s(f)}})()},[u]);let d=window.JBrowseSession?.version,A=[i?"Error loading source map, showing raw stack trace below:":"",l.length>Yv?`${l.slice(0,Yv)}...`:l,n||"No stack trace available",d?`JBrowse ${d}`:""].filter(Boolean).join(`
+`);return(0,Ir.jsxs)(sr.Dialog,{open:!0,onClose:t,maxWidth:"xl",children:[(0,Ir.jsxs)(sr.DialogTitle,{children:["Stack trace",(0,Ir.jsx)(sr.IconButton,{onClick:t,sx:{position:"absolute",right:8,top:8},children:(0,Ir.jsx)(Qf,{})})]}),(0,Ir.jsx)(sr.DialogContent,{children:n===void 0?(0,Ir.jsx)(Wg,{variant:"h6"}):(0,Ir.jsx)($g,{text:A,extra:r})}),(0,Ir.jsxs)(sr.DialogActions,{children:[(0,Ir.jsx)(sr.Button,{variant:"contained",color:"secondary",onClick:async()=>{let{default:f}=await Promise.resolve().then(()=>p(Wv(),1));f(A),c(!0),setTimeout(()=>{c(!1)},1e3)},children:a?"Copied!":"Copy stack trace to clipboard"}),(0,Ir.jsx)(sr.Button,{variant:"contained",color:"primary",onClick:t,children:"Close"})]})]})}var Ir,Ks,sr,qv,Yg,h8,y8,Yv,Xv=m(()=>{Ir=p(O(),1),Ks=p(Q(),1);Qg();sr=p(U(),1),qv=p(Qv(),1);Pv();Uv();Yg={},h8=/\/\/# sourceMappingURL=(.*)/,y8=/(.*)((?:https?|file):\/\/.*):(\d+):(\d+)/;Yv=1e4});function I8(e){let t="",r="is not assignable",n=e.indexOf(r);if(n!==-1){let o=e.slice(0,n+r.length),i=/.*at path "(.*)" snapshot `(.*)` is not assignable/m.exec(o);i&&(e=`Failed to load element at ${i[1]}...Failed element had snapshot`,t=i[2]);let s=/.*snapshot `(.*)` is not assignable/.exec(o);s&&(e="Failed to load element...Failed element had snapshot",t=s[1])}return t}function S8({error:e,onReset:t}){let{classes:r}=Zv(),[n,o]=(0,Zs.useState)(!1);return(0,Xt.jsxs)("div",{className:r.iconFloat,children:[typeof e=="object"&&e&&"stack"in e?(0,Xt.jsx)(Xs.Tooltip,{title:"Get stack trace",children:(0,Xt.jsx)(Xs.IconButton,{onClick:()=>{o(!0)},color:"primary",children:(0,Xt.jsx)(rv,{})})}):null,t?(0,Xt.jsx)(Xs.Tooltip,{title:"Retry",children:(0,Xt.jsx)(Xs.IconButton,{onClick:t,color:"primary",children:(0,Xt.jsx)(ZS,{})})}):null,n?(0,Xt.jsx)(Zs.Suspense,{fallback:null,children:(0,Xt.jsx)(w8,{error:e,onClose:()=>{o(!1)}})}):null]})}function v8({error:e,onReset:t}){let{classes:r}=Zv(),n=`${e}`,o=n.indexOf("expected an instance of"),i=o!==-1?n.slice(0,o):n,s=I8(n);return(0,Xt.jsxs)(_g,{children:[i.slice(0,1e4),(0,Xt.jsx)(S8,{error:e,onReset:t}),s?(0,Xt.jsx)("pre",{className:r.bg,children:JSON.stringify(JSON.parse(s),null,2)}):null]})}var Xt,Zs,Xs,w8,Zv,e1,t1=m(()=>{Xt=p(O(),1),Zs=p(Q(),1);ev();nv();Xs=p(U(),1);iv();He();w8=(0,Zs.lazy)(()=>Promise.resolve().then(()=>(Xv(),Kv))),Zv=Z()(e=>({bg:{background:e.palette.divider,border:"1px solid black",margin:20},iconFloat:{float:"right",marginLeft:100}}));e1=v8});var n1=X((Kre,r1)=>{"use strict";var B8=/["'&<>]/;r1.exports=T8;function T8(e){var t=""+e,r=B8.exec(t);if(!r)return t;var n,o="",i=0,s=0;for(i=r.index;i<t.length;i++){switch(t.charCodeAt(i)){case 34:n="&quot;";break;case 38:n="&amp;";break;case 39:n="&#39;";break;case 60:n="&lt;";break;case 62:n="&gt;";break;default:continue}s!==i&&(o+=t.substring(s,i)),s=i+1,o+=n}return s!==i?o+t.substring(s,i):o}});function Gf(e,t=0){let r=e.getUint32(t,!0);return e.getUint32(t+4,!0)*4294967296+r}var o1=m(()=>{});function M8(e,t){let r=new Array(t+1);r[0]=[0,0];let n=new DataView(e.buffer,e.byteOffset,e.byteLength);for(let o=0;o<t;o+=1){let i=o*qg;r[o+1]=[Gf(n,i),Gf(n,i+8)]}return r}function R8(e,t){let r=0,n=e.length;for(;r<n;){let o=r+n>>>1;e[o][1]<=t?r=o+1:n=o}return r}var qg,Vc,i1=m(()=>{o1();qg=16;Vc=class{filehandle;index;constructor({filehandle:t}){this.filehandle=t}_getIndex(){return this.index||(this.index=this._readIndex().catch(t=>{throw this.index=void 0,t})),this.index}async _readIndex(){let t=await this.filehandle.read(8,0),r=Gf(new DataView(t.buffer,t.byteOffset,t.byteLength));if(r===0)return[[0,0]];if(r>Number.MAX_SAFE_INTEGER/qg)throw new TypeError("integer overflow");let n=await this.filehandle.read(qg*r,8);return M8(n,r)}async getRelevantBlocksForRead(t,r){if(t===0)return{blocks:[],nextCompressedPosition:void 0};let n=await this._getIndex(),o=r+t,i=R8(n,r)-1,s=i+1;for(;s<n.length&&n[s][1]<o;)s+=1;return{blocks:n.slice(i,s),nextCompressedPosition:n[s]?.[0]}}}});var zg,Jg,jc,xo,$c,s1,a1,Kg=m(()=>{zg=0,Jg=2,jc=4,xo=0,$c=1,s1=2,a1=-5});function Q8(e,t){return Object.prototype.hasOwnProperty.call(e,t)}function c1(e){for(var t=Array.prototype.slice.call(arguments,1);t.length;){var r=t.shift();if(r){if(typeof r!="object")throw new TypeError(r+"must be non-object");for(var n in r)Q8(r,n)&&(e[n]=r[n])}}return e}function Hf(e,t){return e.length===t?e:e.subarray?e.subarray(0,t):(e.length=t,e)}var Wc,Yc,ea,gn,Uf,Yn,Co,Ci,qc=m(()=>{Wc={arraySet:function(e,t,r,n,o){if(t.subarray&&e.subarray){e.set(t.subarray(r,r+n),o);return}for(var i=0;i<n;i++)e[o+i]=t[r+i]},flattenChunks:function(e){var t,r,n,o,i,s;for(n=0,t=0,r=e.length;t<r;t++)n+=e[t].length;for(s=new Uint8Array(n),o=0,t=0,r=e.length;t<r;t++)i=e[t],s.set(i,o),o+=i.length;return s},Buf8:function(e){return new Uint8Array(e)},Buf16:function(e){return new Uint16Array(e)},Buf32:function(e){return new Int32Array(e)}},Yc={arraySet:function(e,t,r,n,o){for(var i=0;i<n;i++)e[o+i]=t[r+i]},flattenChunks:function(e){return[].concat.apply([],e)},Buf8:function(e){return new Array(e)},Buf16:function(e){return new Array(e)},Buf32:function(e){return new Array(e)}},ea=()=>{let e=typeof Uint8Array<"u"&&typeof Uint16Array<"u"&&typeof Int32Array<"u";return ea=()=>e,e},gn=(e,t,r,n,o)=>(gn=ea()?Wc.arraySet:Yc.arraySet,gn(e,t,r,n,o)),Uf=e=>(Uf=ea()?Wc.flattenChunks:Yc.flattenChunks,Uf(e)),Yn=e=>(Yn=ea()?Wc.Buf8:Yc.Buf8,Yn(e)),Co=e=>(Co=ea()?Wc.Buf16:Yc.Buf16,Co(e)),Ci=e=>(Ci=ea()?Wc.Buf32:Yc.Buf32,Ci(e))});function Zg(e){var t,r,n,o,i,s=e.length,a=0;for(o=0;o<s;o++)r=e.charCodeAt(o),(r&64512)===55296&&o+1<s&&(n=e.charCodeAt(o+1),(n&64512)===56320&&(r=65536+(r-55296<<10)+(n-56320),o++)),a+=r<128?1:r<2048?2:r<65536?3:4;for(t=new Uint8Array(a),i=0,o=0;i<a;o++)r=e.charCodeAt(o),(r&64512)===55296&&o+1<s&&(n=e.charCodeAt(o+1),(n&64512)===56320&&(r=65536+(r-55296<<10)+(n-56320),o++)),r<128?t[i++]=r:r<2048?(t[i++]=192|r>>>6,t[i++]=128|r&63):r<65536?(t[i++]=224|r>>>12,t[i++]=128|r>>>6&63,t[i++]=128|r&63):(t[i++]=240|r>>>18,t[i++]=128|r>>>12&63,t[i++]=128|r>>>6&63,t[i++]=128|r&63);return t}function _8(e,t){if(t<65534&&(e.subarray&&u1()||!e.subarray&&l1()))return String.fromCharCode.apply(null,Hf(e,t));for(var r="",n=0;n<t;n++)r+=String.fromCharCode(e[n]);return r}function f1(e){for(var t=new Uint8Array(e.length),r=0,n=t.length;r<n;r++)t[r]=e.charCodeAt(r);return t}function d1(e,t){var r,n,o,i,s=t||e.length,a=new Array(s*2);for(n=0,r=0;r<s;){if(o=e[r++],o<128){a[n++]=o;continue}if(i=Xg(o),i>4){a[n++]=65533,r+=i-1;continue}for(o&=i===2?31:i===3?15:7;i>1&&r<s;)o=o<<6|e[r++]&63,i--;if(i>1){a[n++]=65533;continue}o<65536?a[n++]=o:(o-=65536,a[n++]=55296|o>>10&1023,a[n++]=56320|o&1023)}return _8(a,n)}function A1(e,t){var r;for(t=t||e.length,t>e.length&&(t=e.length),r=t-1;r>=0&&(e[r]&192)===128;)r--;return r<0||r===0?t:r+Xg(e[r])>t?r:t}var l1,u1,Xg,m1=m(()=>{qc();l1=function(){let e=!0;try{String.fromCharCode.apply(null,[0])}catch{e=!1}return l1=()=>e,e},u1=function(){let e=!0;try{String.fromCharCode.apply(null,new Uint8Array(1))}catch{e=!1}return u1=()=>e,e},Xg=function(e){for(var t=Yn(256),r=0;r<256;r++)t[r]=r>=252?6:r>=248?5:r>=240?4:r>=224?3:r>=192?2:1;return t[254]=t[254]=1,Xg=n=>t[n],t[e]}});function eh(){this.text=0,this.time=0,this.xflags=0,this.os=0,this.extra=null,this.extra_len=0,this.name="",this.comment="",this.hcrc=0,this.done=!1}var p1=m(()=>{});function zc(e,t,r,n){for(var o=e&65535|0,i=e>>>16&65535|0,s=0;r!==0;){s=r>2e3?2e3:r,r-=s;do o=o+t[n++]|0,i=i+o|0;while(--s);o%=65521,i%=65521}return o|i<<16|0}var g1=m(()=>{});function k8(){for(var e,t=[],r=0;r<256;r++){e=r;for(var n=0;n<8;n++)e=e&1?3988292384^e>>>1:e>>>1;t[r]=e}return t}function Sr(e,t,r,n){var o=h1(),i=n+r;e^=-1;for(var s=n;s<i;s++)e=e>>>8^o[(e^t[s])&255];return e^-1}var h1,y1=m(()=>{h1=function(){let e=k8();return h1=()=>e,e}});function th(e,t){var r,n,o,i,s,a,c,l,u,d,A,f,g,h,x,w,y,v,b,I,S,B,R,D,L;r=e.state,n=e.next_in,D=e.input,o=n+(e.avail_in-5),i=e.next_out,L=e.output,s=i-(t-e.avail_out),a=i+(e.avail_out-257),c=r.dmax,l=r.wsize,u=r.whave,d=r.wnext,A=r.window,f=r.hold,g=r.bits,h=r.lencode,x=r.distcode,w=(1<<r.lenbits)-1,y=(1<<r.distbits)-1;e:do{g<15&&(f+=D[n++]<<g,g+=8,f+=D[n++]<<g,g+=8),v=h[f&w];t:for(;;){if(b=v>>>24,f>>>=b,g-=b,b=v>>>16&255,b===0)L[i++]=v&65535;else if(b&16){I=v&65535,b&=15,b&&(g<b&&(f+=D[n++]<<g,g+=8),I+=f&(1<<b)-1,f>>>=b,g-=b),g<15&&(f+=D[n++]<<g,g+=8,f+=D[n++]<<g,g+=8),v=x[f&y];r:for(;;){if(b=v>>>24,f>>>=b,g-=b,b=v>>>16&255,b&16){if(S=v&65535,b&=15,g<b&&(f+=D[n++]<<g,g+=8,g<b&&(f+=D[n++]<<g,g+=8)),S+=f&(1<<b)-1,S>c){e.msg="invalid distance too far back",r.mode=Vf;break e}if(f>>>=b,g-=b,b=i-s,S>b){if(b=S-b,b>u&&r.sane){e.msg="invalid distance too far back",r.mode=Vf;break e}if(B=0,R=A,d===0){if(B+=l-b,b<I){I-=b;do L[i++]=A[B++];while(--b);B=i-S,R=L}}else if(d<b){if(B+=l+d-b,b-=d,b<I){I-=b;do L[i++]=A[B++];while(--b);if(B=0,d<I){b=d,I-=b;do L[i++]=A[B++];while(--b);B=i-S,R=L}}}else if(B+=d-b,b<I){I-=b;do L[i++]=A[B++];while(--b);B=i-S,R=L}for(;I>2;)L[i++]=R[B++],L[i++]=R[B++],L[i++]=R[B++],I-=3;I&&(L[i++]=R[B++],I>1&&(L[i++]=R[B++]))}else{B=i-S;do L[i++]=L[B++],L[i++]=L[B++],L[i++]=L[B++],I-=3;while(I>2);I&&(L[i++]=L[B++],I>1&&(L[i++]=L[B++]))}}else if((b&64)===0){v=x[(v&65535)+(f&(1<<b)-1)];continue r}else{e.msg="invalid distance code",r.mode=Vf;break e}break}}else if((b&64)===0){v=h[(v&65535)+(f&(1<<b)-1)];continue t}else if(b&32){r.mode=D8;break e}else{e.msg="invalid literal/length code",r.mode=Vf;break e}break}}while(n<o&&i<a);I=g>>3,n-=I,g-=I<<3,f&=(1<<g)-1,e.next_in=n,e.next_out=i,e.avail_in=n<o?5+(o-n):5-(n-o),e.avail_out=i<a?257+(a-i):257-(i-a),r.hold=f,r.bits=g}var Vf,D8,x1=m(()=>{Vf=30,D8=12});function Ei(e,t,r,n,o,i,s,a){var c=a.bits,l=0,u=0,d=0,A=0,f=0,g=0,h=0,x=0,w=0,y=0,v,b,I,S,B,R=null,D=0,L,P=Co(ta+1),C=Co(ta+1),M=null,k=0,G,j,oe;for(l=0;l<=ta;l++)P[l]=0;for(u=0;u<n;u++)P[t[r+u]]++;for(f=c,A=ta;A>=1&&P[A]===0;A--);if(f>A&&(f=A),A===0)return o[i++]=1<<24|64<<16|0,o[i++]=1<<24|64<<16|0,a.bits=1,0;for(d=1;d<A&&P[d]===0;d++);for(f<d&&(f=d),x=1,l=1;l<=ta;l++)if(x<<=1,x-=P[l],x<0)return-1;if(x>0&&(e===b1||A!==1))return-1;for(C[1]=0,l=1;l<ta;l++)C[l+1]=C[l]+P[l];for(u=0;u<n;u++)t[r+u]!==0&&(s[C[t[r+u]]++]=u);if(e===b1?(R=M=s,L=19):e===rh?(R=N8,D-=257,M=L8,k-=257,L=256):(R=F8,M=P8,L=-1),y=0,u=0,l=d,B=i,g=f,h=0,I=-1,w=1<<f,S=w-1,e===rh&&w>C1||e===w1&&w>E1)return 1;for(;;){G=l-h,s[u]<L?(j=0,oe=s[u]):s[u]>L?(j=M[k+s[u]],oe=R[D+s[u]]):(j=96,oe=0),v=1<<l-h,b=1<<g,d=b;do b-=v,o[B+(y>>h)+b]=G<<24|j<<16|oe|0;while(b!==0);for(v=1<<l-1;y&v;)v>>=1;if(v!==0?(y&=v-1,y+=v):y=0,u++,--P[l]===0){if(l===A)break;l=t[r+s[u]]}if(l>f&&(y&S)!==I){for(h===0&&(h=f),B+=d,g=l-h,x=1<<g;g+h<A&&(x-=P[g+h],!(x<=0));)g++,x<<=1;if(w+=1<<g,e===rh&&w>C1||e===w1&&w>E1)return 1;I=y&S,o[I]=f<<24|g<<16|B-i|0}}return y!==0&&(o[B+y]=l-h<<24|64<<16|0),a.bits=f,0}var ta,C1,E1,b1,rh,w1,N8,L8,F8,P8,I1=m(()=>{qc();ta=15,C1=852,E1=592,b1=0,rh=1,w1=2,N8=[3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0],L8=[16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78],F8=[1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0],P8=[16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64]});function q1(e){return(e>>>24&255)+(e>>>8&65280)+((e&65280)<<8)+((e&255)<<24)}function Y8(){this.mode=0,this.last=!1,this.wrap=0,this.havedict=!1,this.flags=0,this.dmax=0,this.check=0,this.total=0,this.head=null,this.wbits=0,this.wsize=0,this.whave=0,this.wnext=0,this.window=null,this.hold=0,this.bits=0,this.length=0,this.offset=0,this.extra=0,this.lencode=null,this.distcode=null,this.lenbits=0,this.distbits=0,this.ncode=0,this.nlen=0,this.ndist=0,this.have=0,this.next=null,this.lens=Co(320),this.work=Co(288),this.lendyn=null,this.distdyn=null,this.sane=0,this.back=0,this.was=0}function q8(e){var t;return!e||!e.state?vr:(t=e.state,e.total_in=e.total_out=t.total=0,e.msg="",t.wrap&&(e.adler=t.wrap&1),t.mode=Z1,t.last=0,t.havedict=0,t.dmax=32768,t.head=null,t.hold=0,t.bits=0,t.lencode=t.lendyn=Ci($8),t.distcode=t.distdyn=Ci(W8),t.sane=1,t.back=-1,bi)}function z8(e){var t;return!e||!e.state?vr:(t=e.state,t.wsize=0,t.whave=0,t.wnext=0,q8(e))}function J8(e,t){var r,n;return!e||!e.state||(n=e.state,t<0?(r=0,t=-t):(r=(t>>4)+1,t<48&&(t&=15)),t&&(t<8||t>15))?vr:(n.window!==null&&n.wbits!==t&&(n.window=null),n.wrap=r,n.wbits=t,z8(e))}function eB(e,t){var r,n;return e?(n=new Y8,e.state=n,n.window=null,r=J8(e,t),r!==bi&&(e.state=null),r):vr}function K8(e){if(z1){var t;for(sh=Ci(512),ah=Ci(32),t=0;t<144;)e.lens[t++]=8;for(;t<256;)e.lens[t++]=9;for(;t<280;)e.lens[t++]=7;for(;t<288;)e.lens[t++]=8;for(Ei(J1,e.lens,0,288,sh,0,e.work,{bits:9}),t=0;t<32;)e.lens[t++]=5;Ei(K1,e.lens,0,32,ah,0,e.work,{bits:5}),z1=!1}e.lencode=sh,e.lenbits=9,e.distcode=ah,e.distbits=5}function tB(e,t,r,n){var o,i=e.state;return i.window===null&&(i.wsize=1<<i.wbits,i.wnext=0,i.whave=0,i.window=Yn(i.wsize)),n>=i.wsize?(gn(i.window,t,r-i.wsize,i.wsize,0),i.wnext=0,i.whave=i.wsize):(o=i.wsize-i.wnext,o>n&&(o=n),gn(i.window,t,r-n,o,i.wnext),n-=o,n?(gn(i.window,t,r-n,n,0),i.wnext=n,i.whave=i.wsize):(i.wnext+=o,i.wnext===i.wsize&&(i.wnext=0),i.whave<i.wsize&&(i.whave+=o))),0}function rB(e,t){var r,n,o,i,s,a,c,l,u,d,A,f,g,h,x=0,w,y,v,b,I,S,B,R,D=Yn(4),L,P,C=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15];if(!e||!e.state||!e.output||!e.input&&e.avail_in!==0)return vr;r=e.state,r.mode===qn&&(r.mode=nh),s=e.next_out,o=e.output,c=e.avail_out,i=e.next_in,n=e.input,a=e.avail_in,l=r.hold,u=r.bits,d=a,A=c,R=bi;e:for(;;)switch(r.mode){case Z1:if(r.wrap===0){r.mode=nh;break}for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(r.wrap&2&&l===35615){r.check=0,D[0]=l&255,D[1]=l>>>8&255,r.check=Sr(r.check,D,2,0),l=0,u=0,r.mode=B1;break}if(r.flags=0,r.head&&(r.head.done=!1),!(r.wrap&1)||(((l&255)<<8)+(l>>8))%31){e.msg="incorrect header check",r.mode=Ne;break}if((l&15)!==v1){e.msg="unknown compression method",r.mode=Ne;break}if(l>>>=4,u-=4,B=(l&15)+8,r.wbits===0)r.wbits=B;else if(B>r.wbits){e.msg="invalid window size",r.mode=Ne;break}r.dmax=1<<B,e.adler=r.check=1,r.mode=l&512?N1:qn,l=0,u=0;break;case B1:for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(r.flags=l,(r.flags&255)!==v1){e.msg="unknown compression method",r.mode=Ne;break}if(r.flags&57344){e.msg="unknown header flags set",r.mode=Ne;break}r.head&&(r.head.text=l>>8&1),r.flags&512&&(D[0]=l&255,D[1]=l>>>8&255,r.check=Sr(r.check,D,2,0)),l=0,u=0,r.mode=T1;case T1:for(;u<32;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.head&&(r.head.time=l),r.flags&512&&(D[0]=l&255,D[1]=l>>>8&255,D[2]=l>>>16&255,D[3]=l>>>24&255,r.check=Sr(r.check,D,4,0)),l=0,u=0,r.mode=M1;case M1:for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.head&&(r.head.xflags=l&255,r.head.os=l>>8),r.flags&512&&(D[0]=l&255,D[1]=l>>>8&255,r.check=Sr(r.check,D,2,0)),l=0,u=0,r.mode=R1;case R1:if(r.flags&1024){for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.length=l,r.head&&(r.head.extra_len=l),r.flags&512&&(D[0]=l&255,D[1]=l>>>8&255,r.check=Sr(r.check,D,2,0)),l=0,u=0}else r.head&&(r.head.extra=null);r.mode=Q1;case Q1:if(r.flags&1024&&(f=r.length,f>a&&(f=a),f&&(r.head&&(B=r.head.extra_len-r.length,r.head.extra||(r.head.extra=new Array(r.head.extra_len)),gn(r.head.extra,n,i,f,B)),r.flags&512&&(r.check=Sr(r.check,n,f,i)),a-=f,i+=f,r.length-=f),r.length))break e;r.length=0,r.mode=_1;case _1:if(r.flags&2048){if(a===0)break e;f=0;do B=n[i+f++],r.head&&B&&r.length<65536&&(r.head.name+=String.fromCharCode(B));while(B&&f<a);if(r.flags&512&&(r.check=Sr(r.check,n,f,i)),a-=f,i+=f,B)break e}else r.head&&(r.head.name=null);r.length=0,r.mode=k1;case k1:if(r.flags&4096){if(a===0)break e;f=0;do B=n[i+f++],r.head&&B&&r.length<65536&&(r.head.comment+=String.fromCharCode(B));while(B&&f<a);if(r.flags&512&&(r.check=Sr(r.check,n,f,i)),a-=f,i+=f,B)break e}else r.head&&(r.head.comment=null);r.mode=D1;case D1:if(r.flags&512){for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(l!==(r.check&65535)){e.msg="header crc mismatch",r.mode=Ne;break}l=0,u=0}r.head&&(r.head.hcrc=r.flags>>9&1,r.head.done=!0),e.adler=r.check=0,r.mode=qn;break;case N1:for(;u<32;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}e.adler=r.check=q1(l),l=0,u=0,r.mode=Yf;case Yf:if(r.havedict===0)return e.next_out=s,e.avail_out=c,e.next_in=i,e.avail_in=a,r.hold=l,r.bits=u,H8;e.adler=r.check=1,r.mode=qn;case qn:if(t===G8||t===jf)break e;case nh:if(r.last){l>>>=u&7,u-=u&7,r.mode=ih;break}for(;u<3;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}switch(r.last=l&1,l>>>=1,u-=1,l&3){case 0:r.mode=L1;break;case 1:if(K8(r),r.mode=$f,t===jf){l>>>=2,u-=2;break e}break;case 2:r.mode=P1;break;case 3:e.msg="invalid block type",r.mode=Ne}l>>>=2,u-=2;break;case L1:for(l>>>=u&7,u-=u&7;u<32;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if((l&65535)!==(l>>>16^65535)){e.msg="invalid stored block lengths",r.mode=Ne;break}if(r.length=l&65535,l=0,u=0,r.mode=oh,t===jf)break e;case oh:r.mode=F1;case F1:if(f=r.length,f){if(f>a&&(f=a),f>c&&(f=c),f===0)break e;gn(o,n,i,f,s),a-=f,i+=f,c-=f,s+=f,r.length-=f;break}r.mode=qn;break;case P1:for(;u<14;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(r.nlen=(l&31)+257,l>>>=5,u-=5,r.ndist=(l&31)+1,l>>>=5,u-=5,r.ncode=(l&15)+4,l>>>=4,u-=4,r.nlen>286||r.ndist>30){e.msg="too many length or distance symbols",r.mode=Ne;break}r.have=0,r.mode=O1;case O1:for(;r.have<r.ncode;){for(;u<3;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.lens[C[r.have++]]=l&7,l>>>=3,u-=3}for(;r.have<19;)r.lens[C[r.have++]]=0;if(r.lencode=r.lendyn,r.lenbits=7,L={bits:r.lenbits},R=Ei(O8,r.lens,0,19,r.lencode,0,r.work,L),r.lenbits=L.bits,R){e.msg="invalid code lengths set",r.mode=Ne;break}r.have=0,r.mode=G1;case G1:for(;r.have<r.nlen+r.ndist;){for(;x=r.lencode[l&(1<<r.lenbits)-1],w=x>>>24,y=x>>>16&255,v=x&65535,!(w<=u);){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(v<16)l>>>=w,u-=w,r.lens[r.have++]=v;else{if(v===16){for(P=w+2;u<P;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(l>>>=w,u-=w,r.have===0){e.msg="invalid bit length repeat",r.mode=Ne;break}B=r.lens[r.have-1],f=3+(l&3),l>>>=2,u-=2}else if(v===17){for(P=w+3;u<P;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}l>>>=w,u-=w,B=0,f=3+(l&7),l>>>=3,u-=3}else{for(P=w+7;u<P;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}l>>>=w,u-=w,B=0,f=11+(l&127),l>>>=7,u-=7}if(r.have+f>r.nlen+r.ndist){e.msg="invalid bit length repeat",r.mode=Ne;break}for(;f--;)r.lens[r.have++]=B}}if(r.mode===Ne)break;if(r.lens[256]===0){e.msg="invalid code -- missing end-of-block",r.mode=Ne;break}if(r.lenbits=9,L={bits:r.lenbits},R=Ei(J1,r.lens,0,r.nlen,r.lencode,0,r.work,L),r.lenbits=L.bits,R){e.msg="invalid literal/lengths set",r.mode=Ne;break}if(r.distbits=6,r.distcode=r.distdyn,L={bits:r.distbits},R=Ei(K1,r.lens,r.nlen,r.ndist,r.distcode,0,r.work,L),r.distbits=L.bits,R){e.msg="invalid distances set",r.mode=Ne;break}if(r.mode=$f,t===jf)break e;case $f:r.mode=Wf;case Wf:if(a>=6&&c>=258){e.next_out=s,e.avail_out=c,e.next_in=i,e.avail_in=a,r.hold=l,r.bits=u,th(e,A),s=e.next_out,o=e.output,c=e.avail_out,i=e.next_in,n=e.input,a=e.avail_in,l=r.hold,u=r.bits,r.mode===qn&&(r.back=-1);break}for(r.back=0;x=r.lencode[l&(1<<r.lenbits)-1],w=x>>>24,y=x>>>16&255,v=x&65535,!(w<=u);){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(y&&(y&240)===0){for(b=w,I=y,S=v;x=r.lencode[S+((l&(1<<b+I)-1)>>b)],w=x>>>24,y=x>>>16&255,v=x&65535,!(b+w<=u);){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}l>>>=b,u-=b,r.back+=b}if(l>>>=w,u-=w,r.back+=w,r.length=v,y===0){r.mode=$1;break}if(y&32){r.back=-1,r.mode=qn;break}if(y&64){e.msg="invalid literal/length code",r.mode=Ne;break}r.extra=y&15,r.mode=U1;case U1:if(r.extra){for(P=r.extra;u<P;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.length+=l&(1<<r.extra)-1,l>>>=r.extra,u-=r.extra,r.back+=r.extra}r.was=r.length,r.mode=H1;case H1:for(;x=r.distcode[l&(1<<r.distbits)-1],w=x>>>24,y=x>>>16&255,v=x&65535,!(w<=u);){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if((y&240)===0){for(b=w,I=y,S=v;x=r.distcode[S+((l&(1<<b+I)-1)>>b)],w=x>>>24,y=x>>>16&255,v=x&65535,!(b+w<=u);){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}l>>>=b,u-=b,r.back+=b}if(l>>>=w,u-=w,r.back+=w,y&64){e.msg="invalid distance code",r.mode=Ne;break}r.offset=v,r.extra=y&15,r.mode=V1;case V1:if(r.extra){for(P=r.extra;u<P;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.offset+=l&(1<<r.extra)-1,l>>>=r.extra,u-=r.extra,r.back+=r.extra}if(r.offset>r.dmax){e.msg="invalid distance too far back",r.mode=Ne;break}r.mode=j1;case j1:if(c===0)break e;if(f=A-c,r.offset>f){if(f=r.offset-f,f>r.whave&&r.sane){e.msg="invalid distance too far back",r.mode=Ne;break}f>r.wnext?(f-=r.wnext,g=r.wsize-f):g=r.wnext-f,f>r.length&&(f=r.length),h=r.window}else h=o,g=s-r.offset,f=r.length;f>c&&(f=c),c-=f,r.length-=f;do o[s++]=h[g++];while(--f);r.length===0&&(r.mode=Wf);break;case $1:if(c===0)break e;o[s++]=r.length,c--,r.mode=Wf;break;case ih:if(r.wrap){for(;u<32;){if(a===0)break e;a--,l|=n[i++]<<u,u+=8}if(A-=c,e.total_out+=A,r.total+=A,A&&(e.adler=r.check=r.flags?Sr(r.check,o,A,s-A):zc(r.check,o,A,s-A)),A=c,(r.flags?l:q1(l))!==r.check){e.msg="incorrect data check",r.mode=Ne;break}l=0,u=0}r.mode=W1;case W1:if(r.wrap&&r.flags){for(;u<32;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(l!==(r.total&4294967295)){e.msg="incorrect length check",r.mode=Ne;break}l=0,u=0}r.mode=Y1;case Y1:R=U8;break e;case Ne:R=X1;break e;case lh:return ch;case j8:default:return vr}return e.next_out=s,e.avail_out=c,e.next_in=i,e.avail_in=a,r.hold=l,r.bits=u,(r.wsize||A!==e.avail_out&&r.mode<Ne&&(r.mode<ih||t!==S1))&&tB(e,e.output,e.next_out,A-e.avail_out)?(r.mode=lh,ch):(d-=e.avail_in,A-=e.avail_out,e.total_in+=d,e.total_out+=A,r.total+=A,r.wrap&&A&&(e.adler=r.check=r.flags?Sr(r.check,o,A,e.next_out-A):zc(r.check,o,A,e.next_out-A)),e.data_type=r.bits+(r.last?64:0)+(r.mode===qn?128:0)+(r.mode===$f||r.mode===oh?256:0),(d===0&&A===0||t===S1)&&R===bi&&(R=V8),R)}function nB(e){if(!e||!e.state)return vr;var t=e.state;return t.window&&(t.window=null),e.state=null,bi}function oB(e,t){var r;return!e||!e.state||(r=e.state,(r.wrap&2)===0)?vr:(r.head=t,t.done=!1,bi)}function uh(e,t){var r=t.length,n,o,i;return!e||!e.state||(n=e.state,n.wrap!==0&&n.mode!==Yf)?vr:n.mode===Yf&&(o=1,o=zc(o,t,r,0),o!==n.check)?X1:(i=tB(e,t,r,r),i?(n.mode=lh,ch):(n.havedict=1,bi))}var O8,J1,K1,S1,G8,jf,bi,U8,H8,vr,X1,ch,V8,v1,Z1,B1,T1,M1,R1,Q1,_1,k1,D1,N1,Yf,qn,nh,L1,oh,F1,P1,O1,G1,$f,Wf,U1,H1,V1,j1,$1,ih,W1,Y1,Ne,lh,j8,$8,W8,z1,sh,ah,iB=m(()=>{g1();y1();x1();I1();qc();O8=0,J1=1,K1=2,S1=4,G8=5,jf=6,bi=0,U8=1,H8=2,vr=-2,X1=-3,ch=-4,V8=-5,v1=8,Z1=1,B1=2,T1=3,M1=4,R1=5,Q1=6,_1=7,k1=8,D1=9,N1=10,Yf=11,qn=12,nh=13,L1=14,oh=15,F1=16,P1=17,O1=18,G1=19,$f=20,Wf=21,U1=22,H1=23,V1=24,j1=25,$1=26,ih=27,W1=28,Y1=29,Ne=30,lh=31,j8=32,$8=852,W8=592;z1=!0});var qf,sB=m(()=>{qf={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible version"}});function fh(){this.input=null,this.next_in=0,this.avail_in=0,this.total_in=0,this.output=null,this.next_out=0,this.avail_out=0,this.total_out=0,this.msg="",this.state=null,this.data_type=2,this.adler=0}var aB=m(()=>{});function X8(e,t){var r=new Ah(t);if(r.push(e,!0),r.err)throw r.msg||qf[r.err];return r.result}var dh,Ah,cB,lB=m(()=>{qc();m1();Kg();p1();iB();sB();aB();dh=Object.prototype.toString,Ah=class e{constructor(t){if(!(this instanceof e))return new e(t);this.options=c1({chunkSize:16384,windowBits:0,to:""},t||{});var r=this.options;r.raw&&r.windowBits>=0&&r.windowBits<16&&(r.windowBits=-r.windowBits,r.windowBits===0&&(r.windowBits=-15)),r.windowBits>=0&&r.windowBits<16&&!(t&&t.windowBits)&&(r.windowBits+=32),r.windowBits>15&&r.windowBits<48&&(r.windowBits&15)===0&&(r.windowBits|=15),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new fh,this.strm.avail_out=0;var n=eB(this.strm,r.windowBits);if(n!==xo)throw new Error(qf[n]);if(this.header=new eh,oB(this.strm,this.header),r.dictionary&&(typeof r.dictionary=="string"?r.dictionary=Zg(r.dictionary):dh.call(r.dictionary)==="[object ArrayBuffer]"&&(r.dictionary=new Uint8Array(r.dictionary)),r.raw&&(n=uh(this.strm,r.dictionary),n!==xo)))throw new Error(qf[n])}push(t,r){var n=this.strm,o=this.options.chunkSize,i=this.options.dictionary,s,a,c,l,u,d,A=!1;if(this.ended)return!1;a=r===~~r?r:r===!0?jc:zg,typeof t=="string"?n.input=f1(t):dh.call(t)==="[object ArrayBuffer]"?n.input=new Uint8Array(t):n.input=t,n.next_in=0,n.avail_in=n.input.length;do{if(n.avail_out===0&&(n.output=Yn(o),n.next_out=0,n.avail_out=o),s=rB(n,zg),s===s1&&i&&(typeof i=="string"?d=Zg(i):dh.call(i)==="[object ArrayBuffer]"?d=new Uint8Array(i):d=i,s=uh(this.strm,d)),s===a1&&A===!0&&(s=xo,A=!1),s!==$c&&s!==xo)return this.onEnd(s),this.ended=!0,!1;n.next_out&&(n.avail_out===0||s===$c||n.avail_in===0&&(a===jc||a===Jg))&&(this.options.to==="string"?(c=A1(n.output,n.next_out),l=n.next_out-c,u=d1(n.output,c),n.next_out=l,n.avail_out=o-l,l&&gn(n.output,n.output,c,l,0),this.onData(u)):this.onData(Hf(n.output,n.next_out))),n.avail_in===0&&n.avail_out===0&&(A=!0)}while((n.avail_in>0||n.avail_out===0)&&s!==$c);return s===$c&&(a=jc),a===jc?(s=nB(this.strm),this.onEnd(s),this.ended=!0,s===xo):(a===Jg&&(this.onEnd(xo),n.avail_out=0),!0)}onData(t){this.chunks.push(t)}onEnd(t){t===xo&&(this.options.to==="string"?this.result=this.chunks.join(""):this.result=Uf(this.chunks)),this.chunks=[],this.err=t,this.msg=this.strm.msg}};cB=X8});var uB=m(()=>{});var fB=m(()=>{Kg();lB();uB()});function mB(e){try{let s=xe.__wbindgen_add_to_stack_pointer(-16),a=hB(e,xe.__wbindgen_export2),c=yh;xe.decompress_all(s,a,c);var t=ar().getInt32(s+0,!0),r=ar().getInt32(s+4,!0),n=ar().getInt32(s+8,!0),o=ar().getInt32(s+12,!0);if(o)throw yB(n);var i=pB(t,r).slice();return xe.__wbindgen_export(t,r*1,1),i}finally{xe.__wbindgen_add_to_stack_pointer(16)}}function e6(e,t,r,n,o){try{let c=xe.__wbindgen_add_to_stack_pointer(-16),l=hB(e,xe.__wbindgen_export2),u=yh;xe.decompress_chunk_slice(c,l,u,t,r,n,o);var i=ar().getInt32(c+0,!0),s=ar().getInt32(c+4,!0),a=ar().getInt32(c+8,!0);if(a)throw yB(s);return na.__wrap(i)}finally{xe.__wbindgen_add_to_stack_pointer(16)}}function t6(e,t){let r=Error(gB(e,t));return n6(r)}function r6(e,t){throw new Error(gB(e,t))}function n6(e){Kc===zn.length&&zn.push(zn.length+1);let t=Kc;return Kc=zn[t],zn[t]=e,t}function o6(e){e<1028||(zn[e]=Kc,Kc=e)}function AB(e,t){return e=e>>>0,i6().subarray(e/8,e/8+t)}function pB(e,t){return e=e>>>0,hh().subarray(e/1,e/1+t)}function ar(){return(ra===null||ra.buffer.detached===!0||ra.buffer.detached===void 0&&ra.buffer!==xe.memory.buffer)&&(ra=new DataView(xe.memory.buffer)),ra}function i6(){return(zf===null||zf.byteLength===0)&&(zf=new Float64Array(xe.memory.buffer)),zf}function gB(e,t){return c6(e>>>0,t)}function hh(){return(Jf===null||Jf.byteLength===0)&&(Jf=new Uint8Array(xe.memory.buffer)),Jf}function s6(e){return zn[e]}function hB(e,t){let r=t(e.length*1,1)>>>0;return hh().set(e,r/1),yh=e.length,r}function yB(e){let t=s6(e);return o6(e),t}function c6(e,t){return mh+=t,mh>=a6&&(Kf=new TextDecoder("utf-8",{ignoreBOM:!0,fatal:!0}),Kf.decode(),mh=t),Kf.decode(hh().subarray(e,e+t))}function xB(e){xe=e}async function l6(){return Jc||(ph||(ph=(async()=>{let t=await(await fetch(Z8)).arrayBuffer(),{instance:r}=await WebAssembly.instantiate(t,{"./bgzf_wasm_bg.js":gh});return Jc=r.exports,xB(Jc),Jc})()),ph)}async function CB(e){return await l6(),mB(e)}var wi,gh,Z8,na,dB,ra,zf,Jf,zn,Kc,Kf,a6,mh,yh,xe,Jc,ph,EB=m(()=>{wi={};wi.d=(e,t)=>{for(var r in t)wi.o(t,r)&&!wi.o(e,r)&&Object.defineProperty(e,r,{enumerable:!0,get:t[r]})};wi.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t);wi.r=e=>{typeof Symbol<"u"&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0})};gh={};wi.r(gh);wi.d(gh,{ChunkSliceResult:()=>na,__wbg_Error_ef53bc310eb298a0:()=>t6,__wbg___wbindgen_throw_1506f2235d1bdba0:()=>r6,__wbg_set_wasm:()=>xB,decompress_all:()=>mB,decompress_chunk_slice:()=>e6});Z8="data:application/wasm;base64,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",na=class e{static __wrap(t){let r=Object.create(e.prototype);return r.__wbg_ptr=t,dB.register(r,r.__wbg_ptr,r),r}__destroy_into_raw(){let t=this.__wbg_ptr;return this.__wbg_ptr=0,dB.unregister(this),t}free(){let t=this.__destroy_into_raw();xe.__wbg_chunksliceresult_free(t,0)}take_buffer(){try{let o=xe.__wbindgen_add_to_stack_pointer(-16);xe.chunksliceresult_take_buffer(o,this.__wbg_ptr);var t=ar().getInt32(o+0,!0),r=ar().getInt32(o+4,!0),n=pB(t,r).slice();return xe.__wbindgen_export(t,r*1,1),n}finally{xe.__wbindgen_add_to_stack_pointer(16)}}take_cpositions(){try{let o=xe.__wbindgen_add_to_stack_pointer(-16);xe.chunksliceresult_take_cpositions(o,this.__wbg_ptr);var t=ar().getInt32(o+0,!0),r=ar().getInt32(o+4,!0),n=AB(t,r).slice();return xe.__wbindgen_export(t,r*8,8),n}finally{xe.__wbindgen_add_to_stack_pointer(16)}}take_dpositions(){try{let o=xe.__wbindgen_add_to_stack_pointer(-16);xe.chunksliceresult_take_dpositions(o,this.__wbg_ptr);var t=ar().getInt32(o+0,!0),r=ar().getInt32(o+4,!0),n=AB(t,r).slice();return xe.__wbindgen_export(t,r*8,8),n}finally{xe.__wbindgen_add_to_stack_pointer(16)}}};Symbol.dispose&&(na.prototype[Symbol.dispose]=na.prototype.free);dB=typeof FinalizationRegistry>"u"?{register:()=>{},unregister:()=>{}}:new FinalizationRegistry(e=>xe.__wbg_chunksliceresult_free(e,1));ra=null;zf=null;Jf=null;zn=new Array(1024).fill(void 0);zn.push(void 0,null,!0,!1);Kc=zn.length;Kf=new TextDecoder("utf-8",{ignoreBOM:!0,fatal:!0});Kf.decode();a6=2146435072,mh=0;yh=0;Jc=null,ph=null});function u6(e){return e[0]===31&&e[1]===139}function bB(e){return e instanceof Error?e.message:`${e}`}async function f6(e){if(typeof DecompressionStream<"u"){let t=new Blob([e]).stream().pipeThrough(new DecompressionStream("gzip"));return new Uint8Array(await new Response(t).arrayBuffer())}else return cB(e,void 0)}function d6(e){return bB(e).includes("invalid gzip header")?new Error("problem decompressing block: incorrect gzip header check",{cause:e}):e}async function Xf(e){try{return await CB(e)}catch(t){if(bB(t).includes("invalid bgzf header")){if(u6(e))return f6(e);throw new Error("problem decompressing block: not a valid bgzf or gzip block",{cause:t})}throw d6(t)}}var xh=m(()=>{fB();EB()});function wB(e){let t=0;for(let o of e)t+=o.length;let r=new Uint8Array(t),n=0;for(let o of e)r.set(o,n),n+=o.length;return r}var IB=m(()=>{});function p6(e){let t=0,r=[],n=()=>{t--,r.shift()?.()};return async o=>{t>=e&&await new Promise(i=>{r.push(i)}),t++;try{return await o()}finally{n()}}}function g6(e,t,r,n){let o=Math.max(0,r-t),i=Math.min(n,t+e.length)-t;return o<e.length?e.subarray(o,i):new Uint8Array(0)}var A6,m6,oa,SB=m(()=>{i1();xh();IB();A6=10,m6=65536;oa=class{filehandle;gzi;limit;constructor({filehandle:t,gziFilehandle:r,blockConcurrency:n=A6}){this.filehandle=t,this.gzi=new Vc({filehandle:r}),this.limit=p6(n)}async _readAndUncompressBlock(t,r){let n=await this.filehandle.read(r,t);return Xf(n)}async read(t,r){let{blocks:n,nextCompressedPosition:o}=await this.gzi.getRelevantBlocksForRead(t,r);if(n.length===0)return new Uint8Array(0);let i=r+t,s=await Promise.all(n.map(([a,c],l)=>this.limit(async()=>{let u=n[l+1]?.[0]??o??a+m6,d=await this._readAndUncompressBlock(a,u-a);return g6(d,c,r,i)})));return wB(s)}}});var Ch=m(()=>{SB();xh()});var Zf=X((Wne,vB)=>{vB.exports=JBrowseExports["react-dom"]});var TB=X((Yne,BB)=>{BB.exports=JBrowseExports["react-dom/client"]});function MB(e){let t="",r=!1;for(let n=0,o=e.length;n<o;n++){let i=e[n];i==="<"?r=!0:i===">"?r=!1:r||(t+=i)}return t}var Eh=m(()=>{});var RB=m(()=>{});var QB=m(()=>{});var _B=m(()=>{});function ed(e){return typeof e=="object"&&e!==null&&"uri"in e&&!!e.uri}var h6,bh=m(()=>{h6=p(zt(),1);_B()});var y6,kB=m(()=>{y6=p(Ls(),1)});var DB=m(()=>{});var NB=m(()=>{});var ia,td,wh,Ih,x6,Xc,rd,LB=m(()=>{ia={METHOD:"method",PROPERTY:"property"},td=class{constructor(t,r){this.inst=t,this.args=r}},wh=class extends td{constructor(t,r){super(t,r),this.type=ia.METHOD}execute(t){t[this.inst](...this.args)}},Ih=class extends td{constructor(t,r){super(t,r),this.type=ia.PROPERTY}execute(t){t[this.inst]=this.args[0]}},x6={[ia.METHOD]:wh,[ia.PROPERTY]:Ih},Xc=class{constructor(t,r,n){return new x6[t](r,n)}};Xc.METHOD=ia.METHOD;Xc.PROPERTY=ia.PROPERTY;rd=Xc});var FB,hn,nd,Sh=m(()=>{LB();FB=Object.freeze({METHODS:["addHitRegion","arc","arcTo","beginPath","bezierCurveTo","clearHitRegions","clearRect","clip","closePath","drawFocusIfNeeded","drawImage","ellipse","fill","fillRect","fillText","lineTo","moveTo","putImageData","quadraticCurveTo","rect","removeHitRegion","resetTransform","restore","rotate","save","scale","scrollPathIntoView","setLineDash","setTransform","stroke","strokeRect","strokeText","transform","translate"],PROPERTIES:["direction","fillStyle","filter","font","globalAlpha","globalCompositeOperation","imageSmoothingEnabled","imageSmoothingQuality","lineCap","lineDashOffset","lineJoin","lineWidth","miterLimit","shadowBlur","shadowColor","shadowOffsetX","shadowOffsetY","strokeStyle","textAlign","textBaseline"]}),hn=Object.freeze({sequence:Symbol.for("sequence"),push:Symbol.for("push"),fromJSON:Symbol.for("fromJSON")}),nd=class{constructor(t=null){this[hn.sequence]=[],t&&this[hn.fromJSON](t)}[hn.fromJSON](t={sequence:[]}){t.sequence.forEach(({type:r,inst:n,args:o})=>{this[hn.push](r,n,o)})}[hn.push](t,r,n){this[hn.sequence].push(new rd(t,r,n))}execute(t){t.save(),this[hn.sequence].forEach(r=>r.execute(t)),t.restore()}toJSON(){return{sequence:this[hn.sequence]}}};FB.METHODS.forEach(e=>{Object.defineProperty(nd.prototype,e,{value:function(...r){this[hn.push](rd.METHOD,e,r)},writable:!1,enumerable:!0,configurable:!1})});FB.PROPERTIES.forEach(e=>{Object.defineProperty(nd.prototype,e,{get(){throw`Invalid canvas sequencer interaction, cannot get ${e}.`},set(t){this[hn.push](rd.PROPERTY,e,[t])},enumerable:!0,configurable:!1})})});var soe,OB=m(()=>{Sh();soe=Object.freeze({sequence:Symbol.for("sequence"),push:Symbol.for("push")})});var GB=m(()=>{OB();Sh()});var HB=X((doe,UB)=>{UB.exports=!1});var C6,VB=m(()=>{GB();C6=p(HB(),1)});var E6,b6,jB=m(()=>{E6=p(O(),1),b6=p(Q(),1)});var $B=m(()=>{});var hoe,yoe,xoe,Coe,WB=m(()=>{hoe=new Uint8Array([99,124,119,123,242,107,111,197,48,1,103,43,254,215,171,118,202,130,201,125,250,89,71,240,173,212,162,175,156,164,114,192,183,253,147,38,54,63,247,204,52,165,229,241,113,216,49,21,4,199,35,195,24,150,5,154,7,18,128,226,235,39,178,117,9,131,44,26,27,110,90,160,82,59,214,179,41,227,47,132,83,209,0,237,32,252,177,91,106,203,190,57,74,76,88,207,208,239,170,251,67,77,51,133,69,249,2,127,80,60,159,168,81,163,64,143,146,157,56,245,188,182,218,33,16,255,243,210,205,12,19,236,95,151,68,23,196,167,126,61,100,93,25,115,96,129,79,220,34,42,144,136,70,238,184,20,222,94,11,219,224,50,58,10,73,6,36,92,194,211,172,98,145,149,228,121,231,200,55,109,141,213,78,169,108,86,244,234,101,122,174,8,186,120,37,46,28,166,180,198,232,221,116,31,75,189,139,138,112,62,181,102,72,3,246,14,97,53,87,185,134,193,29,158,225,248,152,17,105,217,142,148,155,30,135,233,206,85,40,223,140,161,137,13,191,230,66,104,65,153,45,15,176,84,187,22]),yoe=new Uint8Array([82,9,106,213,48,54,165,56,191,64,163,158,129,243,215,251,124,227,57,130,155,47,255,135,52,142,67,68,196,222,233,203,84,123,148,50,166,194,35,61,238,76,149,11,66,250,195,78,8,46,161,102,40,217,36,178,118,91,162,73,109,139,209,37,114,248,246,100,134,104,152,22,212,164,92,204,93,101,182,146,108,112,72,80,253,237,185,218,94,21,70,87,167,141,157,132,144,216,171,0,140,188,211,10,247,228,88,5,184,179,69,6,208,44,30,143,202,63,15,2,193,175,189,3,1,19,138,107,58,145,17,65,79,103,220,234,151,242,207,206,240,180,230,115,150,172,116,34,231,173,53,133,226,249,55,232,28,117,223,110,71,241,26,113,29,41,197,137,111,183,98,14,170,24,190,27,252,86,62,75,198,210,121,32,154,219,192,254,120,205,90,244,31,221,168,51,136,7,199,49,177,18,16,89,39,128,236,95,96,81,127,169,25,181,74,13,45,229,122,159,147,201,156,239,160,224,59,77,174,42,245,176,200,235,187,60,131,83,153,97,23,43,4,126,186,119,214,38,225,105,20,99,85,33,12,125]),xoe=new Uint8Array([1,2,4,8,16,32,64,128,27,54]),Coe=new Uint32Array([1116352408,1899447441,3049323471,3921009573,961987163,1508970993,2453635748,2870763221,3624381080,310598401,607225278,1426881987,1925078388,2162078206,2614888103,3248222580,3835390401,4022224774,264347078,604807628,770255983,1249150122,1555081692,1996064986,2554220882,2821834349,2952996808,3210313671,3336571891,3584528711,113926993,338241895,666307205,773529912,1294757372,1396182291,1695183700,1986661051,2177026350,2456956037,2730485921,2820302411,3259730800,3345764771,3516065817,3600352804,4094571909,275423344,430227734,506948616,659060556,883997877,958139571,1322822218,1537002063,1747873779,1955562222,2024104815,2227730452,2361852424,2428436474,2756734187,3204031479,3329325298])});function Zc(e,t){if(typeof t!="function"&&t!==null)throw new TypeError("Class extends value "+String(t)+" is not a constructor or null");vh(e,t);function r(){this.constructor=e}e.prototype=t===null?Object.create(t):(r.prototype=t.prototype,new r)}function Bh(e){var t=typeof Symbol=="function"&&Symbol.iterator,r=t&&e[t],n=0;if(r)return r.call(e);if(e&&typeof e.length=="number")return{next:function(){return e&&n>=e.length&&(e=void 0),{value:e&&e[n++],done:!e}}};throw new TypeError(t?"Object is not iterable.":"Symbol.iterator is not defined.")}function sa(e,t){var r=typeof Symbol=="function"&&e[Symbol.iterator];if(!r)return e;var n=r.call(e),o,i=[],s;try{for(;(t===void 0||t-- >0)&&!(o=n.next()).done;)i.push(o.value)}catch(a){s={error:a}}finally{try{o&&!o.done&&(r=n.return)&&r.call(n)}finally{if(s)throw s.error}}return i}function aa(e,t,r){if(r||arguments.length===2)for(var n=0,o=t.length,i;n<o;n++)(i||!(n in t))&&(i||(i=Array.prototype.slice.call(t,0,n)),i[n]=t[n]);return e.concat(i||Array.prototype.slice.call(t))}var vh,el=m(()=>{vh=function(e,t){return vh=Object.setPrototypeOf||{__proto__:[]}instanceof Array&&function(r,n){r.__proto__=n}||function(r,n){for(var o in n)Object.prototype.hasOwnProperty.call(n,o)&&(r[o]=n[o])},vh(e,t)}});function yn(e){return typeof e=="function"}var od=m(()=>{});function id(e){var t=function(n){Error.call(n),n.stack=new Error().stack},r=e(t);return r.prototype=Object.create(Error.prototype),r.prototype.constructor=r,r}var Th=m(()=>{});var sd,YB=m(()=>{Th();sd=id(function(e){return function(r){e(this),this.message=r?r.length+` errors occurred during unsubscription:
 `+r.map(function(n,o){return o+1+") "+n.toString()}).join(`
-  `):"",this.name="UnsubscriptionError",this.errors=r}})});function Ch(e,t){if(e){var r=e.indexOf(t);0<=r&&e.splice(r,1)}}var NB=m(()=>{});function PB(e){return e instanceof Kf||e&&"closed"in e&&In(e.remove)&&In(e.add)&&In(e.unsubscribe)}function LB(e){In(e)?e():e.unsubscribe()}var Kf,toe,FB=m(()=>{Xc();qf();DB();NB();Kf=(function(){function e(t){this.initialTeardown=t,this.closed=!1,this._parentage=null,this._finalizers=null}return e.prototype.unsubscribe=function(){var t,r,n,o,i;if(!this.closed){this.closed=!0;var s=this._parentage;if(s)if(this._parentage=null,Array.isArray(s))try{for(var a=yh(s),c=a.next();!c.done;c=a.next()){var l=c.value;l.remove(this)}}catch(h){t={error:h}}finally{try{c&&!c.done&&(r=a.return)&&r.call(a)}finally{if(t)throw t.error}}else s.remove(this);var u=this.initialTeardown;if(In(u))try{u()}catch(h){i=h instanceof Jf?h.errors:[h]}var d=this._finalizers;if(d){this._finalizers=null;try{for(var A=yh(d),f=A.next();!f.done;f=A.next()){var g=f.value;try{LB(g)}catch(h){i=i??[],h instanceof Jf?i=aa(aa([],sa(i)),sa(h.errors)):i.push(h)}}}catch(h){n={error:h}}finally{try{f&&!f.done&&(o=A.return)&&o.call(A)}finally{if(n)throw n.error}}}if(i)throw new Jf(i)}},e.prototype.add=function(t){var r;if(t&&t!==this)if(this.closed)LB(t);else{if(t instanceof e){if(t.closed||t._hasParent(this))return;t._addParent(this)}(this._finalizers=(r=this._finalizers)!==null&&r!==void 0?r:[]).push(t)}},e.prototype._hasParent=function(t){var r=this._parentage;return r===t||Array.isArray(r)&&r.includes(t)},e.prototype._addParent=function(t){var r=this._parentage;this._parentage=Array.isArray(r)?(r.push(t),r):r?[r,t]:t},e.prototype._removeParent=function(t){var r=this._parentage;r===t?this._parentage=null:Array.isArray(r)&&Ch(r,t)},e.prototype.remove=function(t){var r=this._finalizers;r&&Ch(r,t),t instanceof e&&t._removeParent(this)},e.EMPTY=(function(){var t=new e;return t.closed=!0,t})(),e})(),toe=Kf.EMPTY});var Io,Xf=m(()=>{Io={onUnhandledError:null,onStoppedNotification:null,Promise:void 0,useDeprecatedSynchronousErrorHandling:!1,useDeprecatedNextContext:!1}});var ca,bh=m(()=>{Xc();ca={setTimeout:function(e,t){for(var r=[],n=2;n<arguments.length;n++)r[n-2]=arguments[n];var o=ca.delegate;return o?.setTimeout?o.setTimeout.apply(o,aa([e,t],sa(r))):setTimeout.apply(void 0,aa([e,t],sa(r)))},clearTimeout:function(e){var t=ca.delegate;return(t?.clearTimeout||clearTimeout)(e)},delegate:void 0}});function OB(e){ca.setTimeout(function(){var t=Io.onUnhandledError;if(t)t(e);else throw e})}var GB=m(()=>{Xf();bh()});function Eh(){}var UB=m(()=>{});function VB(e){return wh("E",void 0,e)}function jB(e){return wh("N",e,void 0)}function wh(e,t,r){return{kind:e,value:t,error:r}}var HB,$B=m(()=>{HB=(function(){return wh("C",void 0,void 0)})()});function WB(e){Io.useDeprecatedSynchronousErrorHandling&&Ih&&(Ih.errorThrown=!0,Ih.error=e)}var Ih,YB=m(()=>{Xf();Ih=null});function Sh(e,t){return i6.call(e,t)}function Zf(e){Io.useDeprecatedSynchronousErrorHandling?WB(e):OB(e)}function a6(e){throw e}function vh(e,t){var r=Io.onStoppedNotification;r&&ca.setTimeout(function(){return r(e,t)})}var Bh,i6,s6,Th,c6,Mh=m(()=>{Xc();qf();FB();Xf();GB();UB();$B();bh();YB();Bh=(function(e){Kc(t,e);function t(r){var n=e.call(this)||this;return n.isStopped=!1,r?(n.destination=r,PB(r)&&r.add(n)):n.destination=c6,n}return t.create=function(r,n,o){return new Th(r,n,o)},t.prototype.next=function(r){this.isStopped?vh(jB(r),this):this._next(r)},t.prototype.error=function(r){this.isStopped?vh(VB(r),this):(this.isStopped=!0,this._error(r))},t.prototype.complete=function(){this.isStopped?vh(HB,this):(this.isStopped=!0,this._complete())},t.prototype.unsubscribe=function(){this.closed||(this.isStopped=!0,e.prototype.unsubscribe.call(this),this.destination=null)},t.prototype._next=function(r){this.destination.next(r)},t.prototype._error=function(r){try{this.destination.error(r)}finally{this.unsubscribe()}},t.prototype._complete=function(){try{this.destination.complete()}finally{this.unsubscribe()}},t})(Kf),i6=Function.prototype.bind;s6=(function(){function e(t){this.partialObserver=t}return e.prototype.next=function(t){var r=this.partialObserver;if(r.next)try{r.next(t)}catch(n){Zf(n)}},e.prototype.error=function(t){var r=this.partialObserver;if(r.error)try{r.error(t)}catch(n){Zf(n)}else Zf(t)},e.prototype.complete=function(){var t=this.partialObserver;if(t.complete)try{t.complete()}catch(r){Zf(r)}},e})(),Th=(function(e){Kc(t,e);function t(r,n,o){var i=e.call(this)||this,s;if(In(r)||!r)s={next:r??void 0,error:n??void 0,complete:o??void 0};else{var a;i&&Io.useDeprecatedNextContext?(a=Object.create(r),a.unsubscribe=function(){return i.unsubscribe()},s={next:r.next&&Sh(r.next,a),error:r.error&&Sh(r.error,a),complete:r.complete&&Sh(r.complete,a)}):s=r}return i.destination=new s6(s),i}return t})(Bh);c6={closed:!0,next:Eh,error:a6,complete:Eh}});function l6(e){return In(e?.lift)}function ed(e){return function(t){if(l6(t))return t.lift(function(r){try{return e(r,this)}catch(n){this.error(n)}});throw new TypeError("Unable to lift unknown Observable type")}}var Rh=m(()=>{qf()});function qB(e,t,r,n,o){return new u6(e,t,r,n,o)}var u6,zB=m(()=>{Xc();Mh();u6=(function(e){Kc(t,e);function t(r,n,o,i,s,a){var c=e.call(this,r)||this;return c.onFinalize=s,c.shouldUnsubscribe=a,c._next=n?function(l){try{n(l)}catch(u){r.error(u)}}:e.prototype._next,c._error=i?function(l){try{i(l)}catch(u){r.error(u)}finally{this.unsubscribe()}}:e.prototype._error,c._complete=o?function(){try{o()}catch(l){r.error(l)}finally{this.unsubscribe()}}:e.prototype._complete,c}return t.prototype.unsubscribe=function(){var r;if(!this.shouldUnsubscribe||this.shouldUnsubscribe()){var n=this.closed;e.prototype.unsubscribe.call(this),!n&&((r=this.onFinalize)===null||r===void 0||r.call(this))}},t})(Bh)});var JB,KB=m(()=>{xh();JB=zf(function(e){return function(){e(this),this.name="EmptyError",this.message="no elements in sequence"}})});function Qh(e,t){var r=typeof t=="object";return new Promise(function(n,o){var i=new Th({next:function(s){n(s),i.unsubscribe()},error:o,complete:function(){r?n(t.defaultValue):o(new JB)}});e.subscribe(i)})}var XB=m(()=>{KB();Mh()});var ZB=m(()=>{});function eT(e,t,r,n,o){return function(i,s){var a=r,c=t,l=0;i.subscribe(qB(s,function(u){var d=l++;c=a?e(c,u,d):(a=!0,u),n&&s.next(c)},o&&(function(){a&&s.next(c),s.complete()})))}}var tT=m(()=>{zB()});function rT(e,t){return ed(eT(e,t,arguments.length>=2,!1,!0))}var nT=m(()=>{tT();Rh()});function _h(){return ed(function(e,t){rT(f6,[])(e).subscribe(t)})}var f6,oT=m(()=>{nT();Rh();f6=function(e,t){return e.push(t),e}});var iT=m(()=>{XB();ZB();oT()});var sT=m(()=>{});var aT=m(()=>{});function d6(){return cT||(cT=[IDBDatabase,IDBObjectStore,IDBIndex,IDBCursor,IDBTransaction])}function A6(){return lT||(lT=[IDBCursor.prototype.advance,IDBCursor.prototype.continue,IDBCursor.prototype.continuePrimaryKey])}function m6(e){let t=new Promise((r,n)=>{let o=()=>{e.removeEventListener("success",i),e.removeEventListener("error",s)},i=()=>{r(Ii(e.result)),o()},s=()=>{n(e.error),o()};e.addEventListener("success",i),e.addEventListener("error",s)});return td.set(t,e),t}function p6(e){if(Lh.has(e))return;let t=new Promise((r,n)=>{let o=()=>{e.removeEventListener("complete",i),e.removeEventListener("error",s),e.removeEventListener("abort",s)},i=()=>{r(),o()},s=()=>{n(e.error||new DOMException("AbortError","AbortError")),o()};e.addEventListener("complete",i),e.addEventListener("error",s),e.addEventListener("abort",s)});Lh.set(e,t)}function AT(e){Ph=e(Ph)}function g6(e){return A6().includes(e)?function(...t){return e.apply(Fh(this),t),Ii(this.request)}:function(...t){return Ii(e.apply(Fh(this),t))}}function h6(e){return typeof e=="function"?g6(e):(e instanceof IDBTransaction&&p6(e),Nh(e,d6())?new Proxy(e,Ph):e)}function Ii(e){if(e instanceof IDBRequest)return m6(e);if(kh.has(e))return kh.get(e);let t=h6(e);return t!==e&&(kh.set(e,t),td.set(t,e)),t}function Gh(e,t,{blocked:r,upgrade:n,blocking:o,terminated:i}={}){let s=indexedDB.open(e,t),a=Ii(s);return n&&s.addEventListener("upgradeneeded",c=>{n(Ii(s.result),c.oldVersion,c.newVersion,Ii(s.transaction),c)}),r&&s.addEventListener("blocked",c=>r(c.oldVersion,c.newVersion,c)),a.then(c=>{i&&c.addEventListener("close",()=>i()),o&&c.addEventListener("versionchange",l=>o(l.oldVersion,l.newVersion,l))}).catch(()=>{}),a}function uT(e,t){if(!(e instanceof IDBDatabase&&!(t in e)&&typeof t=="string"))return;if(Dh.get(t))return Dh.get(t);let r=t.replace(/FromIndex$/,""),n=t!==r,o=x6.includes(r);if(!(r in(n?IDBIndex:IDBObjectStore).prototype)||!(o||y6.includes(r)))return;let i=async function(s,...a){let c=this.transaction(s,o?"readwrite":"readonly"),l=c.store;return n&&(l=l.index(a.shift())),(await Promise.all([l[r](...a),o&&c.done]))[0]};return Dh.set(t,i),i}async function*E6(...e){let t=this;if(t instanceof IDBCursor||(t=await t.openCursor(...e)),!t)return;t=t;let r=new Proxy(t,b6);for(mT.set(r,t),td.set(r,Fh(t));t;)yield r,t=await(Oh.get(r)||t.continue()),Oh.delete(r)}function dT(e,t){return t===Symbol.asyncIterator&&Nh(e,[IDBIndex,IDBObjectStore,IDBCursor])||t==="iterate"&&Nh(e,[IDBIndex,IDBObjectStore])}var Nh,cT,lT,Lh,kh,td,Ph,Fh,y6,x6,Dh,C6,fT,Oh,mT,b6,Uh=m(()=>{Nh=(e,t)=>t.some(r=>e instanceof r);Lh=new WeakMap,kh=new WeakMap,td=new WeakMap;Ph={get(e,t,r){if(e instanceof IDBTransaction){if(t==="done")return Lh.get(e);if(t==="store")return r.objectStoreNames[1]?void 0:r.objectStore(r.objectStoreNames[0])}return Ii(e[t])},set(e,t,r){return e[t]=r,!0},has(e,t){return e instanceof IDBTransaction&&(t==="done"||t==="store")?!0:t in e}};Fh=e=>td.get(e);y6=["get","getKey","getAll","getAllKeys","count"],x6=["put","add","delete","clear"],Dh=new Map;AT(e=>({...e,get:(t,r,n)=>uT(t,r)||e.get(t,r,n),has:(t,r)=>!!uT(t,r)||e.has(t,r)}));C6=["continue","continuePrimaryKey","advance"],fT={},Oh=new WeakMap,mT=new WeakMap,b6={get(e,t){if(!C6.includes(t))return e[t];let r=fT[t];return r||(r=fT[t]=function(...n){Oh.set(this,mT.get(this)[t](...n))}),r}};AT(e=>({...e,get(t,r,n){return dT(t,r)?E6:e.get(t,r,n)},has(t,r){return dT(t,r)||e.has(t,r)}}))});var pT=m(()=>{Uh()});var rd,gT=m(()=>{rd=p(Kt(),1)});function Vh(e,t=10){let r=String(e),n=0;for(let o=0,i=r.length;o<i;o++)n+=S6[r.charCodeAt(o)]??v6;return n*t}function jh(e){let t=0;if(e.length===0)return t;for(let r=0;r<e.length;r++){let n=e.charCodeAt(r);t=(t<<5)-t+n,t|=0}return t}function B6(e){let{uri:t,baseUri:r=""}=e,n;try{n=new URL(t,r).href}catch{n=t}return n}function $h(e){return _r(e)?jf(e)?B6(e):JSON.stringify(e):String(e)}function hT(e){let t=/(^|[\s\n]|<[A-Za-z]*\/?>)((?:https?|ftp):\/\/[-A-Z0-9+\u0026\u2019@#/%?=()~_|!:,.;]*[-A-Z0-9+\u0026@#/%=~()_|])/gi;return e.replaceAll(t,`$1<a href='$2' target="_blank">$2</a>`)}function yT(e,t){let{padding:r=30,minWidth:n=80,fontSize:o=12,maxWidth:i=1e3,stripHTML:s=!1}=t||{};return Wh(e.map(a=>$h(a)).map(a=>s?gB(a):a).map(a=>Vh(a,o)).map(a=>Math.min(Math.max(a+r,n),i)))}function Wh(e,t=Number.NEGATIVE_INFINITY){let r=t;for(let n of e)r=Math.max(n,r);return r}function _r(e){return typeof e=="object"&&e!==null}var Hh,la,w6,I6,oie,iie,sie,aie,S6,v6,So=m(()=>{Hh=p(Q(),1);fh();la=p(Kt(),1),w6=p(Vf(),1),I6=p(pB(),1);dh();Ah();Ah();CB();bB();EB();dh();RB();QB();_B();kB();sT();aT();hB();yB();gT();pT();oie=180/Math.PI,iie=Math.PI/180,sie=/electron/i.test(typeof navigator<"u"?navigator.userAgent:""),aie=typeof jest>"u"?typeof window<"u"&&window.requestIdleCallback?window.requestIdleCallback:e=>setTimeout(()=>{e()},1):e=>{e()},S6=[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,.2796875,.2765625,.3546875,.5546875,.5546875,.8890625,.665625,.190625,.3328125,.3328125,.3890625,.5828125,.2765625,.3328125,.2765625,.3015625,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.2765625,.2765625,.584375,.5828125,.584375,.5546875,1.0140625,.665625,.665625,.721875,.721875,.665625,.609375,.7765625,.721875,.2765625,.5,.665625,.5546875,.8328125,.721875,.7765625,.665625,.7765625,.721875,.665625,.609375,.721875,.665625,.94375,.665625,.665625,.609375,.2765625,.3546875,.2765625,.4765625,.5546875,.3328125,.5546875,.5546875,.5,.5546875,.5546875,.2765625,.5546875,.5546875,.221875,.240625,.5,.221875,.8328125,.5546875,.5546875,.5546875,.5546875,.3328125,.5,.2765625,.5546875,.5,.721875,.5,.5,.5,.3546875,.259375,.353125,.5890625],v6=.5279276315789471});function xT(e,t){(t==null||t>e.length)&&(t=e.length);for(var r=0,n=Array(t);r<t;r++)n[r]=e[r];return n}function T6(e){if(Array.isArray(e))return e}function M6(e,t){var r=e==null?null:typeof Symbol<"u"&&e[Symbol.iterator]||e["@@iterator"];if(r!=null){var n,o,i,s,a=[],c=!0,l=!1;try{if(i=(r=r.call(e)).next,t!==0)for(;!(c=(n=i.call(r)).done)&&(a.push(n.value),a.length!==t);c=!0);}catch(u){l=!0,o=u}finally{try{if(!c&&r.return!=null&&(s=r.return(),Object(s)!==s))return}finally{if(l)throw o}}return a}}function R6(){throw new TypeError(`Invalid attempt to destructure non-iterable instance.
-In order to be iterable, non-array objects must have a [Symbol.iterator]() method.`)}function Q6(e,t){return T6(e)||M6(e,t)||_6(e,t)||R6()}function _6(e,t){if(e){if(typeof e=="string")return xT(e,t);var r={}.toString.call(e).slice(8,-1);return r==="Object"&&e.constructor&&(r=e.constructor.name),r==="Map"||r==="Set"?Array.from(e):r==="Arguments"||/^(?:Ui|I)nt(?:8|16|32)(?:Clamped)?Array$/.test(r)?xT(e,t):void 0}}function tt(e){return function(t){t instanceof RegExp&&(t.lastIndex=0);for(var r=arguments.length,n=new Array(r>1?r-1:0),o=1;o<r;o++)n[o-1]=arguments[o];return Xh(e,t,n)}}function U6(e){return function(){for(var t=arguments.length,r=new Array(t),n=0;n<t;n++)r[n]=arguments[n];return Zh(e,r)}}function ne(e,t){let r=arguments.length>2&&arguments[2]!==void 0?arguments[2]:tl;if(CT&&CT(e,null),!Bo(t))return e;let n=t.length;for(;n--;){let o=t[n];if(typeof o=="string"){let i=r(o);i!==o&&(k6(t)||(t[n]=i),o=i)}e[o]=!0}return e}function H6(e){for(let t=0;t<e.length;t++)mt(e,t)||(e[t]=null);return e}function Vt(e){let t=da(null);for(let n of DT(e)){var r=Q6(n,2);let o=r[0],i=r[1];mt(e,o)&&(Bo(i)?t[o]=H6(i):i&&typeof i=="object"&&i.constructor===Object?t[o]=Vt(i):t[o]=i)}return t}function V6(e){switch(typeof e){case"string":return e;case"number":return O6(e);case"boolean":return G6(e);case"bigint":return IT?IT(e):"0";case"symbol":return ST?ST(e):"Symbol()";case"undefined":return el(e);case"function":case"object":{if(e===null)return el(e);let t=e,r=Sn(t,"toString");if(typeof r=="function"){let n=r(t);return typeof n=="string"?n:el(n)}return el(e)}default:return el(e)}}function Sn(e,t){for(;e!==null;){let n=N6(e,t);if(n){if(n.get)return tt(n.get);if(typeof n.value=="function")return tt(n.value)}e=D6(e)}function r(){return null}return r}function j6(e){try{return At(e,""),!0}catch{return!1}}function LT(){let e=arguments.length>0&&arguments[0]!==void 0?arguments[0]:oU(),t=P=>LT(P);if(t.version="3.4.12",t.removed=[],!e||!e.document||e.document.nodeType!==ur.document||!e.Element)return t.isSupported=!1,t;let r=e.document,n=r,o=n.currentScript;e.DocumentFragment;let i=e.HTMLTemplateElement,s=e.Node,a=e.Element,c=e.NodeFilter,l=e.NamedNodeMap;l===void 0&&(e.NamedNodeMap||e.MozNamedAttrMap),e.HTMLFormElement;let u=e.DOMParser,d=e.trustedTypes,A=a.prototype,f=Sn(A,"cloneNode"),g=Sn(A,"remove"),h=Sn(A,"nextSibling"),y=Sn(A,"childNodes"),E=Sn(A,"parentNode"),x=Sn(A,"shadowRoot"),S=Sn(A,"attributes"),w=s&&s.prototype?Sn(s.prototype,"nodeType"):null,I=s&&s.prototype?Sn(s.prototype,"nodeName"):null;if(typeof i=="function"){let P=r.createElement("template");P.content&&P.content.ownerDocument&&(r=P.content.ownerDocument)}let v,B="",R,D=!1,L=0,F=function(){if(L>0)throw Si('A configured TRUSTED_TYPES_POLICY callback (createHTML or createScriptURL) must not call DOMPurify.sanitize, as that causes infinite recursion. Do not pass a policy whose callbacks wrap DOMPurify as TRUSTED_TYPES_POLICY; see the "DOMPurify and Trusted Types" section of the README.')},C=function(b){F(),L++;try{return v.createHTML(b)}finally{L--}},M=function(b){F(),L++;try{return v.createScriptURL(b)}finally{L--}},k=function(){return D||(R=iU(d,o),D=!0),R},G=r,j=G.implementation,oe=G.createNodeIterator,te=G.createDocumentFragment,Gr=G.getElementsByTagName,it=n.importNode,de=kT();t.isSupported=typeof DT=="function"&&typeof E=="function"&&j&&j.createHTMLDocument!==void 0;let Ur=Y6,xr=q6,un=z6,Pn=J6,Ki=K6,Fn=X6,co=Z6,YA=tU,Ha=RT,ve=null,Ol=ne({},[...vT,...qh,...zh,...Jh,...BT]),ke=null,lo=ne({},[...TT,...Kh,...MT,...nd]),Be=Object.seal(da(null,{tagNameCheck:{writable:!0,configurable:!1,enumerable:!0,value:null},attributeNameCheck:{writable:!0,configurable:!1,enumerable:!0,value:null},allowCustomizedBuiltInElements:{writable:!0,configurable:!1,enumerable:!0,value:!1}})),Xi=null,Ae=null,ae=Object.seal(da(null,{tagCheck:{writable:!0,configurable:!1,enumerable:!0,value:null},attributeCheck:{writable:!0,configurable:!1,enumerable:!0,value:null}})),De=!0,Te=!0,rr=!1,Pt=!0,ye=!1,Je=!0,nr=!1,On=!1,Zi=null,es=null,It=!1,St=!1,uo=!1,ts=!1,rs=!0,Bx=!1,Tx="user-content-",qA=!0,zA=!1,ns={},fn=null,JA=ne({},["annotation-xml","audio","colgroup","desc","foreignobject","head","iframe","math","mi","mn","mo","ms","mtext","noembed","noframes","noscript","plaintext","script","selectedcontent","style","svg","template","thead","title","video","xmp"]),Mx=null,Rx=ne({},["audio","video","img","source","image","track"]),KA=null,Qx=ne({},["alt","class","for","id","label","name","pattern","placeholder","role","summary","title","value","style","xmlns"]),Gl="http://www.w3.org/1998/Math/MathML",Ul="http://www.w3.org/2000/svg",dn="http://www.w3.org/1999/xhtml",os=dn,XA=!1,ZA=null,vF=ne({},[Gl,Ul,dn],Yh),_x=Ct(["mi","mo","mn","ms","mtext"]),em=ne({},_x),kx=Ct(["annotation-xml"]),tm=ne({},kx),BF=ne({},["title","style","font","a","script"]),Va=null,TF=["application/xhtml+xml","text/html"],MF="text/html",Fe=null,is=null,RF=r.createElement("form"),Dx=function(b){return b instanceof RegExp||b instanceof Function},rm=function(){let b=arguments.length>0&&arguments[0]!==void 0?arguments[0]:{};if(is&&is===b)return;(!b||typeof b!="object")&&(b={}),b=Vt(b),Va=TF.indexOf(b.PARSER_MEDIA_TYPE)===-1?MF:b.PARSER_MEDIA_TYPE,Fe=Va==="application/xhtml+xml"?Yh:tl,ve=vo(b,"ALLOWED_TAGS",Ol,{transform:Fe}),ke=vo(b,"ALLOWED_ATTR",lo,{transform:Fe}),ZA=vo(b,"ALLOWED_NAMESPACES",vF,{transform:Yh}),KA=vo(b,"ADD_URI_SAFE_ATTR",Qx,{transform:Fe,base:Qx}),Mx=vo(b,"ADD_DATA_URI_TAGS",Rx,{transform:Fe,base:Rx}),fn=vo(b,"FORBID_CONTENTS",JA,{transform:Fe}),Xi=vo(b,"FORBID_TAGS",Vt({}),{transform:Fe}),Ae=vo(b,"FORBID_ATTR",Vt({}),{transform:Fe}),ns=mt(b,"USE_PROFILES")?b.USE_PROFILES&&typeof b.USE_PROFILES=="object"?Vt(b.USE_PROFILES):b.USE_PROFILES:!1,De=b.ALLOW_ARIA_ATTR!==!1,Te=b.ALLOW_DATA_ATTR!==!1,rr=b.ALLOW_UNKNOWN_PROTOCOLS||!1,Pt=b.ALLOW_SELF_CLOSE_IN_ATTR!==!1,ye=b.SAFE_FOR_TEMPLATES||!1,Je=b.SAFE_FOR_XML!==!1,nr=b.WHOLE_DOCUMENT||!1,St=b.RETURN_DOM||!1,uo=b.RETURN_DOM_FRAGMENT||!1,ts=b.RETURN_TRUSTED_TYPE||!1,It=b.FORCE_BODY||!1,rs=b.SANITIZE_DOM!==!1,Bx=b.SANITIZE_NAMED_PROPS||!1,qA=b.KEEP_CONTENT!==!1,zA=b.IN_PLACE||!1,Ha=j6(b.ALLOWED_URI_REGEXP)?b.ALLOWED_URI_REGEXP:RT,os=typeof b.NAMESPACE=="string"?b.NAMESPACE:dn,em=mt(b,"MATHML_TEXT_INTEGRATION_POINTS")&&b.MATHML_TEXT_INTEGRATION_POINTS&&typeof b.MATHML_TEXT_INTEGRATION_POINTS=="object"?Vt(b.MATHML_TEXT_INTEGRATION_POINTS):ne({},_x),tm=mt(b,"HTML_INTEGRATION_POINTS")&&b.HTML_INTEGRATION_POINTS&&typeof b.HTML_INTEGRATION_POINTS=="object"?Vt(b.HTML_INTEGRATION_POINTS):ne({},kx);let T=mt(b,"CUSTOM_ELEMENT_HANDLING")&&b.CUSTOM_ELEMENT_HANDLING&&typeof b.CUSTOM_ELEMENT_HANDLING=="object"?Vt(b.CUSTOM_ELEMENT_HANDLING):da(null);if(Be=da(null),mt(T,"tagNameCheck")&&Dx(T.tagNameCheck)&&(Be.tagNameCheck=T.tagNameCheck),mt(T,"attributeNameCheck")&&Dx(T.attributeNameCheck)&&(Be.attributeNameCheck=T.attributeNameCheck),mt(T,"allowCustomizedBuiltInElements")&&typeof T.allowCustomizedBuiltInElements=="boolean"&&(Be.allowCustomizedBuiltInElements=T.allowCustomizedBuiltInElements),bt(Be),ye&&(Te=!1),uo&&(St=!0),ns&&(ve=ne({},BT),ke=da(null),ns.html===!0&&(ne(ve,vT),ne(ke,TT)),ns.svg===!0&&(ne(ve,qh),ne(ke,Kh),ne(ke,nd)),ns.svgFilters===!0&&(ne(ve,zh),ne(ke,Kh),ne(ke,nd)),ns.mathMl===!0&&(ne(ve,Jh),ne(ke,MT),ne(ke,nd))),ae.tagCheck=null,ae.attributeCheck=null,mt(b,"ADD_TAGS")&&(typeof b.ADD_TAGS=="function"?ae.tagCheck=b.ADD_TAGS:Bo(b.ADD_TAGS)&&(ve===Ol&&(ve=Vt(ve)),ne(ve,b.ADD_TAGS,Fe))),mt(b,"ADD_ATTR")&&(typeof b.ADD_ATTR=="function"?ae.attributeCheck=b.ADD_ATTR:Bo(b.ADD_ATTR)&&(ke===lo&&(ke=Vt(ke)),ne(ke,b.ADD_ATTR,Fe))),mt(b,"ADD_URI_SAFE_ATTR")&&Bo(b.ADD_URI_SAFE_ATTR)&&ne(KA,b.ADD_URI_SAFE_ATTR,Fe),mt(b,"FORBID_CONTENTS")&&Bo(b.FORBID_CONTENTS)&&(fn===JA&&(fn=Vt(fn)),ne(fn,b.FORBID_CONTENTS,Fe)),mt(b,"ADD_FORBID_CONTENTS")&&Bo(b.ADD_FORBID_CONTENTS)&&(fn===JA&&(fn=Vt(fn)),ne(fn,b.ADD_FORBID_CONTENTS,Fe)),qA&&(ve["#text"]=!0),nr&&ne(ve,["html","head","body"]),ve.table&&(ne(ve,["tbody"]),delete Xi.tbody),b.TRUSTED_TYPES_POLICY){if(typeof b.TRUSTED_TYPES_POLICY.createHTML!="function")throw Si('TRUSTED_TYPES_POLICY configuration option must provide a "createHTML" hook.');if(typeof b.TRUSTED_TYPES_POLICY.createScriptURL!="function")throw Si('TRUSTED_TYPES_POLICY configuration option must provide a "createScriptURL" hook.');let N=v;v=b.TRUSTED_TYPES_POLICY;try{B=C("")}catch(V){throw v=N,V}}else b.TRUSTED_TYPES_POLICY===null?(v=void 0,B=""):(v===void 0&&(v=k()),v&&typeof B=="string"&&(B=C("")));Ct&&Ct(b),is=b},Nx=ne({},[...qh,...zh,...$6]),Lx=ne({},[...Jh,...W6]),QF=function(b,T,N){return T.namespaceURI===dn?b==="svg":T.namespaceURI===Gl?b==="svg"&&(N==="annotation-xml"||em[N]):!!Nx[b]},_F=function(b,T,N){return T.namespaceURI===dn?b==="math":T.namespaceURI===Ul?b==="math"&&tm[N]:!!Lx[b]},kF=function(b,T,N){return T.namespaceURI===Ul&&!tm[N]||T.namespaceURI===Gl&&!em[N]?!1:!Lx[b]&&(BF[b]||!Nx[b])},DF=function(b){let T=E(b);(!T||!T.tagName)&&(T={namespaceURI:os,tagName:"template"});let N=tl(b.tagName),V=tl(T.tagName);return ZA[b.namespaceURI]?b.namespaceURI===Ul?QF(N,T,V):b.namespaceURI===Gl?_F(N,T,V):b.namespaceURI===dn?kF(N,T,V):!!(Va==="application/xhtml+xml"&&ZA[b.namespaceURI]):!1},fo=function(b){fa(t.removed,{element:b});try{E(b).removeChild(b)}catch{if(g(b),!E(b))throw Si("a node selected for removal could not be detached from its tree and cannot be safely returned; refusing to sanitize in place")}},Hl=function(b){nm(b);let T=y(b);if(T){let V=[];ua(T,q=>{fa(V,q)}),ua(V,q=>{try{g(q)}catch{}})}let N=S(b);if(N)for(let V=N.length-1;V>=0;--V){let q=N[V],J=q&&q.name;if(typeof J=="string")try{b.removeAttribute(J)}catch{}}},zo=function(b,T){try{fa(t.removed,{attribute:T.getAttributeNode(b),from:T})}catch{fa(t.removed,{attribute:null,from:T})}if(T.removeAttribute(b),b==="is")if(St||uo)try{fo(T)}catch{}else try{T.setAttribute(b,"")}catch{}},NF=function(b){let T=S(b);if(T)for(let N=T.length-1;N>=0;--N){let V=T[N],q=V&&V.name;if(!(typeof q!="string"||ke[Fe(q)]))try{b.removeAttribute(q)}catch{}}},nm=function(b){let T=[b];for(;T.length>0;){let N=T.pop();(w?w(N):N.nodeType)===ur.element&&NF(N);let q=y(N);if(q)for(let J=q.length-1;J>=0;--J)T.push(q[J])}},LF=function(b){if(!Je)return;let T=[b];for(;T.length>0;){let N=T.pop(),V=w?w(N):N.nodeType;if(V===ur.processingInstruction||V===ur.comment&&At(_T,N.data)){try{g(N)}catch{}continue}if(V===ur.element){let J=N,He=Fe(I?I(N):N.nodeName);try{J.hasAttribute&&J.hasAttribute("patchsrc")&&J.removeAttribute("patchsrc"),J.hasAttribute&&J.hasAttribute("for")&&He!=="label"&&He!=="output"&&J.removeAttribute("for")}catch{}}let q=y(N);if(q)for(let J=q.length-1;J>=0;--J)T.push(q[J])}},Px=function(b){let T=null,N=null;if(It)b="<remove></remove>"+b;else{let J=ET(b,/^[\r\n\t ]+/);N=J&&J[0]}Va==="application/xhtml+xml"&&os===dn&&(b='<html xmlns="http://www.w3.org/1999/xhtml"><head></head><body>'+b+"</body></html>");let V=v?C(b):b;if(os===dn)try{T=new u().parseFromString(V,Va)}catch{}if(!T||!T.documentElement){T=j.createDocument(os,"template",null);try{T.documentElement.innerHTML=XA?B:V}catch{}}let q=T.body||T.documentElement;return b&&N&&q.insertBefore(r.createTextNode(N),q.childNodes[0]||null),os===dn?Gr.call(T,nr?"html":"body")[0]:nr?T.documentElement:q},Fx=function(b){return oe.call(b.ownerDocument||b,b,c.SHOW_ELEMENT|c.SHOW_COMMENT|c.SHOW_TEXT|c.SHOW_PROCESSING_INSTRUCTION|c.SHOW_CDATA_SECTION,null)},Vl=function(b){return b=Zc(b,Ur," "),b=Zc(b,xr," "),b=Zc(b,un," "),b},om=function(b){var T;b.normalize();let N=oe.call(b.ownerDocument||b,b,c.SHOW_TEXT|c.SHOW_COMMENT|c.SHOW_CDATA_SECTION|c.SHOW_PROCESSING_INSTRUCTION,null),V=N.nextNode();for(;V;)V.data=Vl(V.data),V=N.nextNode();let q=(T=b.querySelectorAll)===null||T===void 0?void 0:T.call(b,"template");q&&ua(q,J=>{ss(J.content)&&om(J.content)})},jl=function(b){let T=I?I(b):null;return typeof T!="string"||Fe(T)!=="form"?!1:typeof b.nodeName!="string"||typeof b.textContent!="string"||typeof b.removeChild!="function"||b.attributes!==S(b)||typeof b.removeAttribute!="function"||typeof b.setAttribute!="function"||typeof b.namespaceURI!="string"||typeof b.insertBefore!="function"||typeof b.hasChildNodes!="function"||b.nodeType!==w(b)||b.childNodes!==y(b)},ss=function(b){if(!w||typeof b!="object"||b===null)return!1;try{return w(b)===ur.documentFragment}catch{return!1}},ja=function(b){if(!w||typeof b!="object"||b===null)return!1;try{return typeof w(b)=="number"}catch{return!1}};function An(P,b,T){P.length!==0&&ua(P,N=>{N.call(t,b,T,is)})}let PF=function(b,T){return!!(Je&&b.hasChildNodes()&&!ja(b.firstElementChild)&&At(QT,b.textContent)&&At(QT,b.innerHTML)||Je&&b.namespaceURI===dn&&T==="style"&&ja(b.firstElementChild)||b.nodeType===ur.processingInstruction||Je&&b.nodeType===ur.comment&&At(_T,b.data))},FF=function(b,T){if(!Xi[T]&&Ux(T)&&(Be.tagNameCheck instanceof RegExp&&At(Be.tagNameCheck,T)||Be.tagNameCheck instanceof Function&&Be.tagNameCheck(T)))return!1;if(qA&&!fn[T]){let N=E(b),V=y(b);if(V&&N){let q=V.length;for(let J=q-1;J>=0;--J){let He=zA?V[J]:f(V[J],!0);N.insertBefore(He,h(b))}}}return fo(b),!0},Ox=function(b,T){if(An(de.beforeSanitizeElements,b,null),b!==T&&E(b)===null)return!0;if(jl(b))return fo(b),!0;let N=Fe(I?I(b):b.nodeName);if(An(de.uponSanitizeElement,b,{tagName:N,allowedTags:ve}),b!==T&&E(b)===null)return!0;if(PF(b,N))return fo(b),!0;if(Xi[N]||!(ae.tagCheck instanceof Function&&ae.tagCheck(N))&&!ve[N]){let q=FF(b,N);return q===!1&&An(de.afterSanitizeElements,b,null),q}if((w?w(b):b.nodeType)===ur.element&&!DF(b)||(N==="noscript"||N==="noembed"||N==="noframes")&&At(rU,b.innerHTML))return fo(b),!0;if(ye&&b.nodeType===ur.text){let q=Vl(b.textContent);b.textContent!==q&&(fa(t.removed,{element:b.cloneNode()}),b.textContent=q)}return An(de.afterSanitizeElements,b,null),!1},Gx=function(b,T,N){if(Ae[T]||Je&&T==="patchsrc"||Je&&T==="for"&&b!=="label"&&b!=="output"||rs&&(T==="id"||T==="name")&&(N in r||N in RF))return!1;let V=ke[T]||ae.attributeCheck instanceof Function&&ae.attributeCheck(T,b);if(!(Te&&At(Pn,T))){if(!(De&&At(Ki,T))){if(V){if(!KA[T]){if(!At(Ha,Zc(N,co,""))){if(!((T==="src"||T==="xlink:href"||T==="href")&&b!=="script"&&wT(N,"data:")===0&&Mx[b])){if(!(rr&&!At(Fn,Zc(N,co,"")))){if(N)return!1}}}}}else if(!(Ux(b)&&(Be.tagNameCheck instanceof RegExp&&At(Be.tagNameCheck,b)||Be.tagNameCheck instanceof Function&&Be.tagNameCheck(b))&&(Be.attributeNameCheck instanceof RegExp&&At(Be.attributeNameCheck,T)||Be.attributeNameCheck instanceof Function&&Be.attributeNameCheck(T,b))||T==="is"&&Be.allowCustomizedBuiltInElements&&(Be.tagNameCheck instanceof RegExp&&At(Be.tagNameCheck,N)||Be.tagNameCheck instanceof Function&&Be.tagNameCheck(N))))return!1}}return!0},OF=ne({},["annotation-xml","color-profile","font-face","font-face-format","font-face-name","font-face-src","font-face-uri","missing-glyph"]),Ux=function(b){return!OF[tl(b)]&&At(YA,b)},GF=function(b,T,N,V){if(v&&typeof d=="object"&&typeof d.getAttributeType=="function"&&!N)switch(d.getAttributeType(b,T)){case"TrustedHTML":return C(V);case"TrustedScriptURL":return M(V)}return V},UF=function(b,T,N,V){try{N?b.setAttributeNS(N,T,V):b.setAttribute(T,V),jl(b)?fo(b):bT(t.removed)}catch{zo(T,b)}},Hx=function(b){An(de.beforeSanitizeAttributes,b,null);let T=b.attributes;if(!T||jl(b))return;let N={attrName:"",attrValue:"",keepAttr:!0,allowedAttributes:ke,forceKeepAttr:void 0},V=T.length,q=Fe(b.nodeName);for(;V--;){let J=T[V],He=J.name,vt=J.namespaceURI,Hr=J.value,Jt=Fe(He),Vr=Hr,Ft=He==="value"?Vr:F6(Vr);if(N.attrName=Jt,N.attrValue=Ft,N.keepAttr=!0,N.forceKeepAttr=void 0,An(de.uponSanitizeAttribute,b,N),Ft=N.attrValue,Bx&&(Jt==="id"||Jt==="name")&&wT(Ft,Tx)!==0&&(zo(He,b),Ft=Tx+Ft),Je&&At(/((--!?|])>)|<\/(style|script|title|xmp|textarea|noscript|iframe|noembed|noframes)/i,Ft)){zo(He,b);continue}if(Jt==="attributename"&&ET(Ft,"href")){zo(He,b);continue}if(!N.forceKeepAttr){if(!N.keepAttr){zo(He,b);continue}if(!Pt&&At(nU,Ft)){zo(He,b);continue}if(ye&&(Ft=Vl(Ft)),!Gx(q,Jt,Ft)){zo(He,b);continue}Ft=GF(q,Jt,vt,Ft),Ft!==Vr&&UF(b,He,vt,Ft)}}An(de.afterSanitizeAttributes,b,null)},$l=function(b){let T=null,N=Fx(b);for(An(de.beforeSanitizeShadowDOM,b,null);T=N.nextNode();)if(An(de.uponSanitizeShadowNode,T,null),Ox(T,b),Hx(T),ss(T.content)&&$l(T.content),(w?w(T):T.nodeType)===ur.element){let q=x(T);ss(q)&&(im(q),$l(q))}An(de.afterSanitizeShadowDOM,b,null)},im=function(b){let T=[{node:b,shadow:null}];for(;T.length>0;){let N=T.pop();if(N.shadow){$l(N.shadow);continue}let V=N.node,J=(w?w(V):V.nodeType)===ur.element,He=y(V);if(He)for(let vt=He.length-1;vt>=0;--vt)T.push({node:He[vt],shadow:null});if(J){let vt=I?I(V):null;if(typeof vt=="string"&&Fe(vt)==="template"){let Hr=V.content;ss(Hr)&&T.push({node:Hr,shadow:null})}}if(J){let vt=x(V);ss(vt)&&T.push({node:null,shadow:vt},{node:vt,shadow:null})}}};return t.sanitize=function(P){let b=arguments.length>1&&arguments[1]!==void 0?arguments[1]:{},T=null,N=null,V=null,q=null;if(XA=!P,XA&&(P="<!-->"),typeof P!="string"&&!ja(P)&&(P=V6(P),typeof P!="string"))throw Si("dirty is not a string, aborting");if(!t.isSupported)return P;On?(ve=Zi,ke=es):rm(b),(de.uponSanitizeElement.length>0||de.uponSanitizeAttribute.length>0)&&(ve=Vt(ve)),de.uponSanitizeAttribute.length>0&&(ke=Vt(ke)),t.removed=[];let J=zA&&typeof P!="string"&&ja(P);if(J){LF(P);let Jt=I?I(P):P.nodeName;if(typeof Jt=="string"){let Vr=Fe(Jt);if(!ve[Vr]||Xi[Vr])throw Hl(P),Si("root node is forbidden and cannot be sanitized in-place")}if(jl(P))throw Hl(P),Si("root node is clobbered and cannot be sanitized in-place");try{im(P)}catch(Vr){throw Hl(P),Vr}}else if(ja(P))T=Px("<!---->"),N=T.ownerDocument.importNode(P,!0),N.nodeType===ur.element&&N.nodeName==="BODY"||N.nodeName==="HTML"?T=N:T.appendChild(N),im(N);else{if(!St&&!ye&&!nr&&P.indexOf("<")===-1)return v&&ts?C(P):P;if(T=Px(P),!T)return St?null:ts?B:""}T&&It&&fo(T.firstChild);let He=J?P:T,vt=Fx(He);try{for(;V=vt.nextNode();)Ox(V,He),Hx(V),ss(V.content)&&$l(V.content)}catch(Jt){throw J&&(Hl(P),ua(t.removed,Vr=>{Vr.element&&nm(Vr.element)})),Jt}if(J)return ua(t.removed,Jt=>{Jt.element&&nm(Jt.element)}),ye&&om(P),P;if(St){if(ye&&om(T),uo)for(q=te.call(T.ownerDocument);T.firstChild;)q.appendChild(T.firstChild);else q=T;return(ke.shadowroot||ke.shadowrootmode)&&(q=it.call(n,q,!0)),q}let Hr=nr?T.outerHTML:T.innerHTML;return nr&&ve["!doctype"]&&T.ownerDocument&&T.ownerDocument.doctype&&T.ownerDocument.doctype.name&&At(eU,T.ownerDocument.doctype.name)&&(Hr="<!DOCTYPE "+T.ownerDocument.doctype.name+`>
-`+Hr),ye&&(Hr=Vl(Hr)),v&&ts?C(Hr):Hr},t.setConfig=function(){let P=arguments.length>0&&arguments[0]!==void 0?arguments[0]:{};rm(P),On=!0,Zi=ve,es=ke},t.clearConfig=function(){is=null,On=!1,Zi=null,es=null,v=R,B=""},t.isValidAttribute=function(P,b,T){is||rm({});let N=Fe(P),V=Fe(b);return Gx(N,V,T)},t.addHook=function(P,b){typeof b=="function"&&mt(de,P)&&fa(de[P],b)},t.removeHook=function(P,b){if(mt(de,P)){if(b!==void 0){let T=L6(de[P],b);return T===-1?void 0:P6(de[P],T,1)[0]}return bT(de[P])}},t.removeHooks=function(P){mt(de,P)&&(de[P]=[])},t.removeAllHooks=function(){de=kT()},t}var DT,CT,k6,D6,N6,Ct,bt,da,NT,Xh,Zh,ua,L6,bT,fa,P6,Bo,tl,Yh,ET,Zc,wT,F6,O6,G6,IT,ST,mt,el,At,Si,vT,qh,zh,$6,Jh,W6,BT,TT,Kh,MT,nd,Y6,q6,z6,J6,K6,RT,X6,Z6,eU,tU,QT,_T,rU,nU,ur,oU,iU,kT,vo,PT,FT=m(()=>{DT=Object.entries,CT=Object.setPrototypeOf,k6=Object.isFrozen,D6=Object.getPrototypeOf,N6=Object.getOwnPropertyDescriptor,Ct=Object.freeze,bt=Object.seal,da=Object.create,NT=typeof Reflect<"u"&&Reflect,Xh=NT.apply,Zh=NT.construct;Ct||(Ct=function(t){return t});bt||(bt=function(t){return t});Xh||(Xh=function(t,r){for(var n=arguments.length,o=new Array(n>2?n-2:0),i=2;i<n;i++)o[i-2]=arguments[i];return t.apply(r,o)});Zh||(Zh=function(t){for(var r=arguments.length,n=new Array(r>1?r-1:0),o=1;o<r;o++)n[o-1]=arguments[o];return new t(...n)});ua=tt(Array.prototype.forEach),L6=tt(Array.prototype.lastIndexOf),bT=tt(Array.prototype.pop),fa=tt(Array.prototype.push),P6=tt(Array.prototype.splice),Bo=Array.isArray,tl=tt(String.prototype.toLowerCase),Yh=tt(String.prototype.toString),ET=tt(String.prototype.match),Zc=tt(String.prototype.replace),wT=tt(String.prototype.indexOf),F6=tt(String.prototype.trim),O6=tt(Number.prototype.toString),G6=tt(Boolean.prototype.toString),IT=typeof BigInt>"u"?null:tt(BigInt.prototype.toString),ST=typeof Symbol>"u"?null:tt(Symbol.prototype.toString),mt=tt(Object.prototype.hasOwnProperty),el=tt(Object.prototype.toString),At=tt(RegExp.prototype.test),Si=U6(TypeError);vT=Ct(["a","abbr","acronym","address","area","article","aside","audio","b","bdi","bdo","big","blink","blockquote","body","br","button","canvas","caption","center","cite","code","col","colgroup","content","data","datalist","dd","decorator","del","details","dfn","dialog","dir","div","dl","dt","element","em","fieldset","figcaption","figure","font","footer","form","h1","h2","h3","h4","h5","h6","head","header","hgroup","hr","html","i","img","input","ins","kbd","label","legend","li","main","map","mark","marquee","menu","menuitem","meter","nav","nobr","ol","optgroup","option","output","p","picture","pre","progress","q","rp","rt","ruby","s","samp","search","section","select","shadow","slot","small","source","spacer","span","strike","strong","style","sub","summary","sup","table","tbody","td","template","textarea","tfoot","th","thead","time","tr","track","tt","u","ul","var","video","wbr"]),qh=Ct(["svg","a","altglyph","altglyphdef","altglyphitem","animatecolor","animatemotion","animatetransform","circle","clippath","defs","desc","ellipse","enterkeyhint","exportparts","filter","font","g","glyph","glyphref","hkern","image","inputmode","line","lineargradient","marker","mask","metadata","mpath","part","path","pattern","polygon","polyline","radialgradient","rect","stop","style","switch","symbol","text","textpath","title","tref","tspan","view","vkern"]),zh=Ct(["feBlend","feColorMatrix","feComponentTransfer","feComposite","feConvolveMatrix","feDiffuseLighting","feDisplacementMap","feDistantLight","feDropShadow","feFlood","feFuncA","feFuncB","feFuncG","feFuncR","feGaussianBlur","feImage","feMerge","feMergeNode","feMorphology","feOffset","fePointLight","feSpecularLighting","feSpotLight","feTile","feTurbulence"]),$6=Ct(["animate","color-profile","cursor","discard","font-face","font-face-format","font-face-name","font-face-src","font-face-uri","foreignobject","hatch","hatchpath","mesh","meshgradient","meshpatch","meshrow","missing-glyph","script","set","solidcolor","unknown","use"]),Jh=Ct(["math","menclose","merror","mfenced","mfrac","mglyph","mi","mlabeledtr","mmultiscripts","mn","mo","mover","mpadded","mphantom","mroot","mrow","ms","mspace","msqrt","mstyle","msub","msup","msubsup","mtable","mtd","mtext","mtr","munder","munderover","mprescripts"]),W6=Ct(["maction","maligngroup","malignmark","mlongdiv","mscarries","mscarry","msgroup","mstack","msline","msrow","semantics","annotation","annotation-xml","mprescripts","none"]),BT=Ct(["#text"]),TT=Ct(["accept","action","align","alt","autocapitalize","autocomplete","autopictureinpicture","autoplay","background","bgcolor","border","capture","cellpadding","cellspacing","checked","cite","class","clear","color","cols","colspan","command","commandfor","controls","controlslist","coords","crossorigin","datetime","decoding","default","dir","disabled","disablepictureinpicture","disableremoteplayback","download","draggable","enctype","enterkeyhint","exportparts","face","for","headers","height","hidden","high","href","hreflang","id","inert","inputmode","integrity","ismap","kind","label","lang","list","loading","loop","low","max","maxlength","media","method","min","minlength","multiple","muted","name","nonce","noshade","novalidate","nowrap","open","optimum","part","pattern","placeholder","playsinline","popover","popovertarget","popovertargetaction","poster","preload","pubdate","radiogroup","readonly","rel","required","rev","reversed","role","rows","rowspan","spellcheck","scope","selected","shape","size","sizes","slot","span","srclang","start","src","srcset","step","style","summary","tabindex","title","translate","type","usemap","valign","value","width","wrap","xmlns"]),Kh=Ct(["accent-height","accumulate","additive","alignment-baseline","amplitude","ascent","attributename","attributetype","azimuth","basefrequency","baseline-shift","begin","bias","by","class","clip","clippathunits","clip-path","clip-rule","color","color-interpolation","color-interpolation-filters","color-profile","color-rendering","cx","cy","d","dx","dy","diffuseconstant","direction","display","divisor","dominant-baseline","dur","edgemode","elevation","end","exponent","fill","fill-opacity","fill-rule","filter","filterunits","flood-color","flood-opacity","font-family","font-size","font-size-adjust","font-stretch","font-style","font-variant","font-weight","fx","fy","g1","g2","glyph-name","glyphref","gradientunits","gradienttransform","height","href","id","image-rendering","in","in2","intercept","k","k1","k2","k3","k4","kerning","keypoints","keysplines","keytimes","lang","lengthadjust","letter-spacing","kernelmatrix","kernelunitlength","lighting-color","local","marker-end","marker-mid","marker-start","markerheight","markerunits","markerwidth","maskcontentunits","maskunits","max","mask","mask-type","media","method","mode","min","name","numoctaves","offset","operator","opacity","order","orient","orientation","origin","overflow","paint-order","path","pathlength","patterncontentunits","patterntransform","patternunits","points","preservealpha","preserveaspectratio","primitiveunits","r","rx","ry","radius","refx","refy","repeatcount","repeatdur","restart","result","rotate","scale","seed","shape-rendering","slope","specularconstant","specularexponent","spreadmethod","startoffset","stddeviation","stitchtiles","stop-color","stop-opacity","stroke-dasharray","stroke-dashoffset","stroke-linecap","stroke-linejoin","stroke-miterlimit","stroke-opacity","stroke","stroke-width","style","surfacescale","systemlanguage","tabindex","tablevalues","targetx","targety","transform","transform-origin","text-anchor","text-decoration","text-orientation","text-rendering","textlength","type","u1","u2","unicode","values","viewbox","visibility","version","vert-adv-y","vert-origin-x","vert-origin-y","width","word-spacing","wrap","writing-mode","xchannelselector","ychannelselector","x","x1","x2","xmlns","y","y1","y2","z","zoomandpan"]),MT=Ct(["accent","accentunder","align","bevelled","close","columnalign","columnlines","columnspacing","columnspan","denomalign","depth","dir","display","displaystyle","encoding","fence","frame","height","href","id","largeop","length","linethickness","lquote","lspace","mathbackground","mathcolor","mathsize","mathvariant","maxsize","minsize","movablelimits","notation","numalign","open","rowalign","rowlines","rowspacing","rowspan","rspace","rquote","scriptlevel","scriptminsize","scriptsizemultiplier","selection","separator","separators","stretchy","subscriptshift","supscriptshift","symmetric","voffset","width","xmlns"]),nd=Ct(["xlink:href","xml:id","xlink:title","xml:space","xmlns:xlink"]),Y6=bt(/{{[\w\W]*|^[\w\W]*}}/g),q6=bt(/<%[\w\W]*|^[\w\W]*%>/g),z6=bt(/\${[\w\W]*/g),J6=bt(/^data-[\-\w.\u00B7-\uFFFF]+$/),K6=bt(/^aria-[\-\w]+$/),RT=bt(/^(?:(?:(?:f|ht)tps?|mailto|tel|callto|sms|cid|xmpp|matrix):|[^a-z]|[a-z+.\-]+(?:[^a-z+.\-:]|$))/i),X6=bt(/^(?:\w+script|data):/i),Z6=bt(/[\u0000-\u0020\u00A0\u1680\u180E\u2000-\u2029\u205F\u3000]/g),eU=bt(/^html$/i),tU=bt(/^[a-z][.\w]*(-[.\w]+)+$/i),QT=bt(/<[/\w!]/g),_T=bt(/<[/\w]/g),rU=bt(/<\/no(script|embed|frames)/i),nU=bt(/\/>/i),ur={element:1,attribute:2,text:3,cdataSection:4,entityReference:5,entityNode:6,processingInstruction:7,comment:8,document:9,documentType:10,documentFragment:11,notation:12},oU=function(){return typeof window>"u"?null:window},iU=function(t,r){if(typeof t!="object"||typeof t.createPolicy!="function")return null;let n=null,o="data-tt-policy-suffix";r&&r.hasAttribute(o)&&(n=r.getAttribute(o));let i="dompurify"+(n?"#"+n:"");try{return t.createPolicy(i,{createHTML(s){return s},createScriptURL(s){return s}})}catch{return console.warn("TrustedTypes policy "+i+" could not be created."),null}},kT=function(){return{afterSanitizeAttributes:[],afterSanitizeElements:[],afterSanitizeShadowDOM:[],beforeSanitizeAttributes:[],beforeSanitizeElements:[],beforeSanitizeShadowDOM:[],uponSanitizeAttribute:[],uponSanitizeElement:[],uponSanitizeShadowNode:[]}},vo=function(t,r,n,o){return mt(t,r)&&Bo(t[r])?ne(o.base?Vt(o.base):{},t[r],o.transform):n};PT=LT()});var UT={};Bt(UT,{default:()=>GT});function GT({value:e,className:t}){let r=(0,od.useRef)(null);return(0,od.useLayoutEffect)(()=>{let n=r.current;if(n)for(let o of n.querySelectorAll("a"))o.setAttribute("rel","noopener noreferrer"),o.setAttribute("target","_blank")},[e]),(0,OT.jsx)("span",{ref:r,className:t,dangerouslySetInnerHTML:{__html:PT.sanitize(e)}})}var OT,od,HT=m(()=>{OT=p(O(),1),od=p(Q(),1);FT()});function lU(e){return cU.test(e)}function uU(e){return e.includes("<")||e.includes("://")}function fU({value:e,className:t}){let r=(0,To.useRef)(null);return(0,To.useLayoutEffect)(()=>{let n=r.current;if(n)try{n.setHTML(e);for(let o of n.querySelectorAll("a"))o.setAttribute("rel","noopener noreferrer"),o.setAttribute("target","_blank")}catch(o){console.error(o)}},[e]),(0,vi.jsx)("span",{ref:r,className:t})}function Mo({html:e,className:t}){let r=`${e}`;if(!uU(r))return(0,vi.jsx)("span",{className:t,children:r});let n=hT(r),o=lU(n)?n:(0,VT.default)(n);return typeof Element<"u"&&Element.prototype.setHTML?(0,vi.jsx)(fU,{value:o,className:t}):(0,vi.jsx)(To.Suspense,{fallback:(0,vi.jsx)("span",{className:t}),children:(0,vi.jsx)(aU,{value:o,className:t})})}var vi,To,VT,sU,aU,cU,e0=m(()=>{vi=p(O(),1),To=p(Q(),1),VT=p(j1(),1);So();sU=["a","b","br","code","div","em","h1","h2","h3","h4","h5","h6","i","img","li","mark","p","pre","span","small","strong","table","tbody","sup","sub","td","tfoot","th","thead","tr","u","ul"],aU=(0,To.lazy)(()=>Promise.resolve().then(()=>(HT(),UT))),cU=new RegExp(sU.map(e=>String.raw`<${e}\b[^>]*>`).join("|"),"i")});function dU({error:e}){let{classes:t}=WT();return(0,fr.jsx)("div",{className:t.errorBox,children:(0,fr.jsx)(U1,{error:e})})}var fr,jT,Rt,$T,WT,AU,YT,qT=m(()=>{fr=p(O(),1),jT=p(Q(),1);Eg();Rt=p(U(),1),$T=p(W(),1);dg();H1();e0();Ve();WT=Z()(e=>({closeButton:{position:"absolute",right:e.spacing(1),top:e.spacing(1),color:e.palette.grey[500]},errorBox:{width:800,margin:40}}));AU=(0,$T.observer)(function(t){let{classes:r}=WT(),{titleNode:n,...o}=t,{title:i,header:s,children:a,onClose:c}=o,l=(0,Rt.useTheme)();return(0,fr.jsx)(Rt.Dialog,{...o,children:(0,fr.jsxs)(Rt.ScopedCssBaseline,{children:[(0,jT.isValidElement)(s)?s:(0,fr.jsxs)(Rt.DialogTitle,{children:[n||(0,fr.jsx)(Mo,{html:i||""}),c?(0,fr.jsx)(Rt.IconButton,{className:r.closeButton,onClick:u=>{c(u,"backdropClick")},children:(0,fr.jsx)(bf,{})}):null]}),(0,fr.jsx)(Rt.Divider,{}),(0,fr.jsx)(Hs,{FallbackComponent:dU,children:(0,fr.jsx)(Rt.ThemeProvider,{theme:(0,Rt.createTheme)(l,{components:{MuiInputBase:{styleOverrides:{input:{boxSizing:"content-box!important"}}}}}),children:a})})]})})}),YT=AU});function t0({onClose:e,helpText:t,label:r}){return(0,Bi.jsx)(YT,{open:!0,onClose:e,title:"Help",titleNode:r?(0,Bi.jsxs)(Bi.Fragment,{children:["Help: ",r]}):void 0,onClick:n=>{n.stopPropagation()},onMouseDown:n=>{n.stopPropagation()},children:(0,Bi.jsx)(zT.DialogContent,{children:t})})}var Bi,zT,JT=m(()=>{Bi=p(O(),1),zT=p(U(),1);qT()});function r0({helpText:e,label:t}){let[r,n]=(0,id.useState)(!1);return(0,Zn.jsxs)(Zn.Fragment,{children:[(0,Zn.jsx)(KT.IconButton,{size:"small",onClick:o=>{o.stopPropagation(),n(!0)},style:{marginLeft:4,padding:4},children:(0,Zn.jsx)(LS,{fontSize:"small"})}),r?(0,Zn.jsxs)(id.Suspense,{fallback:null,children:[(0,Zn.jsx)(t0,{helpText:e,label:t,onClose:o=>{o.stopPropagation(),n(!1)}})," "]}):null]})}var Zn,id,KT,XT=m(()=>{Zn=p(O(),1),id=p(Q(),1);PS();KT=p(U(),1);JT()});var ZT,eM,tM,mU,rM,nM=m(()=>{ZT=p(O(),1),eM=p(Q(),1),tM=p(U(),1),mU=eM.forwardRef(function(t,r){return(0,ZT.jsx)(tM.Menu,{...t,ref:r,style:{pointerEvents:"none",...t.style},slotProps:{...t.slotProps,paper:{style:{pointerEvents:"auto"}}}})}),rM=mU});var oM,iM,sM=m(()=>{"use client";sr();oM=p(O(),1),iM=(0,Me.createSvgIcon)((0,oM.jsx)("path",{d:"m10 17 5-5-5-5z"}),"ArrowRight")});var aM,cM,lM=m(()=>{"use client";sr();aM=p(O(),1),cM=(0,Me.createSvgIcon)((0,aM.jsx)("path",{d:"M19 3H5c-1.11 0-2 .9-2 2v14c0 1.1.89 2 2 2h14c1.11 0 2-.9 2-2V5c0-1.1-.89-2-2-2m-9 14-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8z"}),"CheckBox")});var uM,fM,dM=m(()=>{"use client";sr();uM=p(O(),1),fM=(0,Me.createSvgIcon)((0,uM.jsx)("path",{d:"M19 5v14H5V5zm0-2H5c-1.1 0-2 .9-2 2v14c0 1.1.9 2 2 2h14c1.1 0 2-.9 2-2V5c0-1.1-.9-2-2-2"}),"CheckBoxOutlineBlank")});var AM,mM,pM=m(()=>{"use client";sr();AM=p(O(),1),mM=(0,Me.createSvgIcon)((0,AM.jsx)("path",{d:"M12 7c-2.76 0-5 2.24-5 5s2.24 5 5 5 5-2.24 5-5-2.24-5-5-5m0-5C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m0 18c-4.42 0-8-3.58-8-8s3.58-8 8-8 8 3.58 8 8-3.58 8-8 8"}),"RadioButtonChecked")});var gM,hM,yM=m(()=>{"use client";sr();gM=p(O(),1),hM=(0,Me.createSvgIcon)((0,gM.jsx)("path",{d:"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m0 18c-4.42 0-8-3.58-8-8s3.58-8 8-8 8 3.58 8 8-3.58 8-8 8"}),"RadioButtonUnchecked")});function xM(e){let{classes:t}=pU(),{type:r}=e,n,o;"checked"in e&&({checked:n,disabled:o}=e);let i;switch(r){case"subMenu":{i=(0,Ro.jsx)(iM,{color:"action"});break}case"checkbox":{n?i=(0,Ro.jsx)(cM,{color:o?"inherit":void 0}):i=(0,Ro.jsx)(fM,{color:"action"});break}case"radio":{n?i=(0,Ro.jsx)(mM,{color:o?"inherit":void 0}):i=(0,Ro.jsx)(hM,{color:"action"});break}}return(0,Ro.jsx)("div",{className:t.menuItemEndDecoration,children:i})}var Ro,sd,pU,CM=m(()=>{Ro=p(O(),1);sM();lM();dM();pM();yM();sd=p(U(),1);Ve();pU=Z()({menuItemEndDecoration:{padding:0,margin:0,height:16}})});function bM(e){if(typeof e=="string")return e.toLowerCase().replace(/\s+/g,"_")}function gU({title:e,Icon:t,inset:r,menuItems:n,onMenuItemClick:o,closeAfterItemClick:i,onCloseRoot:s,isOpen:a,onOpen:c,onClose:l}){let[u,d]=(0,n0.useState)(null),A=bM(e);return(0,be.jsxs)(be.Fragment,{children:[(0,be.jsxs)(jt.MenuItem,{ref:d,"data-testid":A?`cascading-submenu-${A}`:void 0,onMouseOver:c,onFocus:c,onClick:c,children:[t?(0,be.jsx)(jt.ListItemIcon,{children:(0,be.jsx)(t,{})}):null,(0,be.jsx)(jt.ListItemText,{primary:e,inset:r}),(0,be.jsx)(kS,{})]}),(0,be.jsx)(rM,{open:a,anchorEl:u,onClose:l,anchorOrigin:{vertical:"top",horizontal:"right"},transformOrigin:{vertical:"top",horizontal:"left"},children:(0,be.jsx)(EM,{closeAfterItemClick:i,onMenuItemClick:o,menuItems:n,onCloseRoot:s})})]})}function EM({onMenuItemClick:e,closeAfterItemClick:t,menuItems:r,onCloseRoot:n}){let[o,i]=(0,n0.useState)(),s=()=>{i(void 0)},a=r.some(u=>"icon"in u&&u.icon),c=r.some(u=>(u.type==="checkbox"||u.type==="radio")&&"helpText"in u&&u.helpText),l=r.toSorted((u,d)=>(d.priority||0)-(u.priority||0));return(0,be.jsx)(be.Fragment,{children:l.map((u,d)=>{if("subMenu"in u)return(0,be.jsx)(gU,{title:u.label,Icon:u.icon,inset:a&&!u.icon,onMenuItemClick:e,menuItems:u.subMenu,closeAfterItemClick:t,onCloseRoot:n,isOpen:o===d,onOpen:()=>{i(d)},onClose:s},`subMenu-${u.label}-${d}`);if(u.type==="divider")return(0,be.jsx)(jt.Divider,{component:"li"},`divider-${d}`);if(u.type==="subHeader")return(0,be.jsx)(jt.ListSubheader,{children:u.label},`subHeader-${u.label}-${d}`);let A=u,f=A.helpText,g=A.type==="checkbox"||A.type==="radio",h=bM(A.label);return(0,be.jsxs)(jt.MenuItem,{"data-testid":h?`cascading-menuitem-${h}`:void 0,disabled:!!A.disabled,onClick:y=>{t&&n(),e(y,A.onClick)},onMouseOver:s,children:[A.icon?(0,be.jsx)(jt.ListItemIcon,{children:(0,be.jsx)(A.icon,{})}):null,(0,be.jsx)(jt.ListItemText,{primary:A.label,secondary:A.subLabel,inset:a&&!A.icon}),(0,be.jsx)("div",{style:{flexGrow:1,minWidth:10}}),g?(0,be.jsx)(xM,{type:A.type,checked:A.checked,disabled:A.disabled}):null,f?(0,be.jsx)(r0,{helpText:f,label:A.label}):g&&c?(0,be.jsx)("div",{style:{marginLeft:4,padding:4,width:28,height:28}}):null]},`${A.label}-${d}`)})})}function o0({onMenuItemClick:e,closeAfterItemClick:t=!0,menuItems:r,open:n,onClose:o,anchorEl:i,anchorOrigin:s,transformOrigin:a,anchorReference:c,anchorPosition:l,slotProps:u,marginThreshold:d,style:A}){let f=Array.isArray(r)?r:r();return(0,be.jsx)(jt.Menu,{anchorEl:i,open:n,onClose:o,anchorOrigin:s,transformOrigin:a,anchorReference:c,anchorPosition:l,slotProps:u,marginThreshold:d??void 0,style:A,children:(0,be.jsx)(EM,{menuItems:f,closeAfterItemClick:t,onMenuItemClick:e,onCloseRoot:o})})}var be,n0,jt,wM=m(()=>{be=p(O(),1),n0=p(Q(),1);DS();jt=p(U(),1);XT();nM();CM()});function hU({children:e,menuItems:t,closeAfterItemClick:r=!0,stopPropagation:n,disabled:o,setOpen:i,ButtonComponent:s=IM.IconButton,onClick:a,anchorOrigin:c,transformOrigin:l,marginThreshold:u,...d}){let[A,f]=(0,ad.useState)(null),g=!!A;(0,ad.useEffect)(()=>{i?.(g)},[g,i]);let h=o??(Array.isArray(t)&&t.length===0);return(0,Ti.jsxs)(Ti.Fragment,{children:[(0,Ti.jsx)(s,{onClick:y=>{n&&y.stopPropagation(),f(y.currentTarget),a?.(y)},...d,disabled:h,children:e}),g?(0,Ti.jsx)(o0,{open:g,onClose:()=>{f(null)},anchorEl:A,anchorOrigin:c,transformOrigin:l,marginThreshold:u,menuItems:t,closeAfterItemClick:r,onMenuItemClick:(y,E)=>{E()}}):null]})}var Ti,ad,IM,vn,Aa=m(()=>{Ti=p(O(),1),ad=p(Q(),1),IM=p(U(),1);wM();vn=hU});var SM,vM,BM=m(()=>{"use client";Ie();SM=p(O(),1),vM=Y((0,SM.jsx)("path",{d:"M12 2C6.49 2 2 6.49 2 12s4.49 10 10 10c1.38 0 2.5-1.12 2.5-2.5 0-.61-.23-1.2-.64-1.67-.08-.1-.13-.21-.13-.33 0-.28.22-.5.5-.5H16c3.31 0 6-2.69 6-6 0-4.96-4.49-9-10-9m5.5 11c-.83 0-1.5-.67-1.5-1.5s.67-1.5 1.5-1.5 1.5.67 1.5 1.5-.67 1.5-1.5 1.5m-3-4c-.83 0-1.5-.67-1.5-1.5S13.67 6 14.5 6s1.5.67 1.5 1.5S15.33 9 14.5 9M5 11.5c0-.83.67-1.5 1.5-1.5s1.5.67 1.5 1.5S7.33 13 6.5 13 5 12.33 5 11.5m6-4c0 .83-.67 1.5-1.5 1.5S8 8.33 8 7.5 8.67 6 9.5 6s1.5.67 1.5 1.5"}),"Palette")});var TM=m(()=>{mp();gp();hp();pp()});var MM,yU,rl,i0=m(()=>{TM();vc();zp();Co();cf([lf]);MM={A:xn[500],C:yn[500],G:Vn[500],T:Wr[500],U:Wr[500]},yU={none:{},nucleotide:MM,clustal:{G:"orange",P:"orange",S:"orange",T:"orange",H:"red",K:"red",R:"red",F:"blue",W:"blue",Y:"blue",I:"green",L:"green",M:"green",V:"green"},lesk:{G:"orange",A:"orange",S:"orange",T:"orange",C:"green",V:"green",I:"green",L:"green",P:"green",F:"green",Y:"green",M:"green",W:"green",N:"magenta",Q:"magenta",H:"magenta",D:"red",E:"red",K:"blue",R:"blue"},maeditor:{A:"lightgreen",G:"lightgreen",C:"green",D:"darkgreen",E:"darkgreen",N:"darkgreen",Q:"darkgreen",I:"blue",L:"blue",M:"blue",V:"blue",F:"#c8a2c8",W:"#c8a2c8",Y:"#c8a2c8",H:"darkblue",K:"orange",R:"orange",P:"pink",S:"red",T:"red"},percent_identity_dynamic:{},flower:{A:"#b18a51",C:"#ff5701",D:"#01a578",E:"#2da0a1",F:"#fa559d",G:"#b1c23c",H:"#0194f9",I:"#f27663",K:"#7fc3d7",L:"#df6e75",M:"#fe9daf",N:"#0bcec6",P:"#4fa32a",Q:"#7295ae",R:"#83bff1",S:"#b4bd9b",T:"#d2b576",V:"#fd997b",W:"#ff2ded",Y:"#c96ecf"},rainbow_dna:{A:"#3737f5",C:"#37f537",G:"#f5f537",T:"#f53737",U:"#f53737"},clustalx_protein:{A:"#197fe5",C:"#e57f7f",D:"#cc4ccc",E:"#cc4ccc",F:"#197fe5",G:"#e5994c",H:"#19b2b2",I:"#197fe5",K:"#e53319",L:"#197fe5",M:"#197fe5",N:"#19cc19",P:"#cccc00",Q:"#19cc19",R:"#e53319",S:"#19cc19",T:"#19cc19",V:"#197fe5",W:"#197fe5",Y:"#19b2b2"},clustalx_protein_dynamic:{},clustalx_dna:{A:"#e53319",C:"#197fe5",G:"#e5994c",T:"#19cc19",U:"#19cc19"},jbrowse_dna:MM,jalview_buried:{A:"#00a35c",R:"#00fc03",N:"#00eb14",D:"#00eb14",C:"#0000ff",Q:"#00f10e",E:"#00f10e",G:"#009d62",H:"#00d52a",I:"#0054ab",L:"#007b84",K:"#00ff00",M:"#009768",F:"#008778",P:"#00e01f",S:"#00d52a",T:"#00db24",W:"#00a857",Y:"#00e619",V:"#005fa0",B:"#00eb14",X:"#00b649",Z:"#00f10e"},jalview_hydrophobicity:{A:"#ad0052",R:"#0000ff",N:"#0c00f3",D:"#0c00f3",C:"#c2003d",Q:"#0c00f3",E:"#0c00f3",G:"#6a0095",H:"#1500ea",I:"#ff0000",L:"#ea0015",K:"#0000ff",M:"#b0004f",F:"#cb0034",P:"#4600b9",S:"#5e00a1",T:"#61009e",W:"#5b00a4",Y:"#4f00b0",V:"#f60009",B:"#0c00f3",X:"#680097",Z:"#0c00f3"},jalview_prophelix:{A:"#e718e7",R:"#6f906f",N:"#1be41b",D:"#778877",C:"#23dc23",Q:"#926d92",E:"#ff00ff",G:"#00ff00",H:"#758a75",I:"#8a758a",L:"#ae51ae",K:"#a05fa0",M:"#ef10ef",F:"#986798",P:"#00ff00",S:"#36c936",T:"#47b847",W:"#8a758a",Y:"#21de21",V:"#857a85",B:"#49b649",X:"#758a75",Z:"#c936c9"},jalview_propstrand:{A:"#5858a7",R:"#6b6b94",N:"#64649b",D:"#2121de",C:"#9d9d62",Q:"#8c8c73",E:"#0000ff",G:"#4949b6",H:"#60609f",I:"#ecec13",L:"#b2b24d",K:"#4747b8",M:"#82827d",F:"#c2c23d",P:"#2323dc",S:"#4949b6",T:"#9d9d62",W:"#c0c03f",Y:"#d3d32c",V:"#ffff00",B:"#4343bc",X:"#797986",Z:"#4747b8"},jalview_propturn:{A:"#2cd3d3",R:"#708f8f",N:"#ff0000",D:"#e81717",C:"#a85757",Q:"#3fc0c0",E:"#778888",G:"#ff0000",H:"#708f8f",I:"#00ffff",L:"#1ce3e3",K:"#7e8181",M:"#1ee1e1",F:"#1ee1e1",P:"#f60909",S:"#e11e1e",T:"#738c8c",W:"#738c8c",Y:"#9d6262",V:"#07f8f8",B:"#f30c0c",X:"#7c8383",Z:"#5ba4a4"},jalview_taylor:{A:"#ccff00",R:"#0000ff",N:"#cc00ff",D:"#ff0000",C:"#ffff00",Q:"#ff00cc",E:"#ff0066",G:"#ff9900",H:"#0066ff",I:"#66ff00",L:"#33ff00",K:"#6600ff",M:"#00ff00",F:"#00ff66",P:"#ffcc00",S:"#ff3300",T:"#ff6600",W:"#00ccff",Y:"#00ffcc",V:"#99ff00"},jalview_zappo:{A:"#ffafaf",R:"#6464ff",N:"#00ff00",D:"#ff0000",C:"#ffff00",Q:"#00ff00",E:"#ff0000",G:"#ff00ff",H:"#6464ff",I:"#ffafaf",L:"#ffafaf",K:"#6464ff",M:"#ffafaf",F:"#ffc800",P:"#ff00ff",S:"#00ff00",T:"#00ff00",W:"#ffc800",Y:"#ffc800",V:"#ffafaf"},cinema:{H:"blue",K:"blue",R:"blue",D:"red",E:"red",S:"green",T:"green",N:"green",Q:"green",A:"white",V:"white",L:"white",I:"white",M:"white",F:"magenta",W:"magenta",Y:"magenta",P:"brown",G:"brown",C:"yellow",B:"gray",Z:"gray",X:"gray","-":"gray",".":"gray"}},rl=Us(yU,([e,t])=>[e,Us(t,([r,n])=>[r,st(n).toHex()])])});var s0,RM,xU,QM,_M=m(()=>{s0=p(Q(),1);Aa();BM();RM=p(W(),1);i0();xU=(0,RM.observer)(function({model:e}){let{colorSchemeName:t}=e;return s0.default.createElement(vn,{"data-testid":"color_scheme_menu",tooltip:"Color scheme",closeAfterItemClick:!0,anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"},menuItems:Object.keys(rl).map(r=>({label:r,type:"radio",checked:t===r,onClick:()=>{e.setColorSchemeName(r)}}))},s0.default.createElement(vM,null))}),QM=xU});var kM,DM,NM=m(()=>{"use client";Ie();kM=p(O(),1),DM=Y((0,kM.jsx)("path",{d:"M19 3h-4.18C14.4 1.84 13.3 1 12 1s-2.4.84-2.82 2H5c-1.1 0-2 .9-2 2v14c0 1.1.9 2 2 2h14c1.1 0 2-.9 2-2V5c0-1.1-.9-2-2-2m-7 0c.55 0 1 .45 1 1s-.45 1-1 1-1-.45-1-1 .45-1 1-1m2 14H7v-2h7zm3-4H7v-2h10zm0-4H7V7h10z"}),"Assignment")});var LM,cd,a0=m(()=>{"use client";Ie();LM=p(O(),1),cd=Y((0,LM.jsx)("path",{d:"M20 6h-8l-2-2H4c-1.1 0-1.99.9-1.99 2L2 18c0 1.1.9 2 2 2h16c1.1 0 2-.9 2-2V8c0-1.1-.9-2-2-2m0 12H4V8h16z"}),"FolderOpen")});var PM,FM,OM=m(()=>{"use client";Ie();PM=p(O(),1),FM=Y((0,PM.jsx)("path",{d:"M3 18h18v-2H3zm0-5h18v-2H3zm0-7v2h18V6z"}),"Menu")});var c0,GM,UM=m(()=>{"use client";Ie();c0=p(O(),1),GM=Y([(0,c0.jsx)("circle",{cx:"12",cy:"12",r:"3.2"},"0"),(0,c0.jsx)("path",{d:"M9 2 7.17 4H4c-1.1 0-2 .9-2 2v12c0 1.1.9 2 2 2h16c1.1 0 2-.9 2-2V6c0-1.1-.9-2-2-2h-3.17L15 2zm3 15c-2.76 0-5-2.24-5-5s2.24-5 5-5 5 2.24 5 5-2.24 5-5 5"},"1")],"PhotoCamera")});var HM,VM,jM=m(()=>{"use client";Ie();HM=p(O(),1),VM=Y((0,HM.jsx)("path",{d:"M4.25 5.61C6.27 8.2 10 13 10 13v6c0 .55.45 1 1 1h2c.55 0 1-.45 1-1v-6s3.72-4.8 5.74-7.39c.51-.66.04-1.61-.79-1.61H5.04c-.83 0-1.3.95-.79 1.61"}),"FilterAlt")});var $M,WM,YM=m(()=>{"use client";Ie();$M=p(O(),1),WM=Y((0,$M.jsx)("path",{d:"M15.5 14h-.79l-.28-.27C15.41 12.59 16 11.11 16 9.5 16 5.91 13.09 3 9.5 3S3 5.91 3 9.5 5.91 16 9.5 16c1.61 0 3.09-.59 4.23-1.57l.27.28v.79l5 4.99L20.49 19zm-6 0C7.01 14 5 11.99 5 9.5S7.01 5 9.5 5 14 7.01 14 9.5 11.99 14 9.5 14"}),"Search")});var qM,zM,JM=m(()=>{"use client";Ie();qM=p(O(),1),zM=Y((0,qM.jsx)("path",{d:"M3 18h6v-2H3zM3 6v2h18V6zm0 7h12v-2H3z"}),"Sort")});var KM,XM,ZM=m(()=>{"use client";Ie();KM=p(O(),1),XM=Y((0,KM.jsx)("path",{d:"M12 4.5C7 4.5 2.73 7.61 1 12c1.73 4.39 6 7.5 11 7.5s9.27-3.11 11-7.5c-1.73-4.39-6-7.5-11-7.5M12 17c-2.76 0-5-2.24-5-5s2.24-5 5-5 5 2.24 5 5-2.24 5-5 5m0-8c-1.66 0-3 1.34-3 3s1.34 3 3 3 3-1.34 3-3-1.34-3-3-3"}),"Visibility")});var tR={};Bt(tR,{default:()=>wU});var pe,eR,ge,ld,CU,bU,EU,wU,rR=m(()=>{pe=p(Q(),1),eR=p(Ze(),1),ge=p(U(),1),ld=p(W(),1),CU=(0,ld.observer)(function({model:e}){let{featureFilters:t}=e;return pe.default.createElement("div",null,pe.default.createElement(ge.Button,{onClick:()=>{for(let r of t.keys())e.setFilter(r,!0)}},"Toggle all on"),pe.default.createElement(ge.Button,{onClick:()=>{for(let r of t.keys())e.setFilter(r,!1)}},"Toggle all off"))}),bU=(0,ld.observer)(function({model:e}){let{tidyInterProAnnotationTypes:t,tidyInterProAnnotations:r,fillPalette:n}=e,o=new Map;for(let i of r)o.set(i.accession,(o.get(i.accession)??0)+1);return pe.default.createElement(pe.default.Fragment,null,pe.default.createElement(CU,{model:e}),pe.default.createElement(ge.Table,{size:"small"},pe.default.createElement(ge.TableHead,null,pe.default.createElement(ge.TableRow,null,pe.default.createElement(ge.TableCell,{padding:"checkbox"}),pe.default.createElement(ge.TableCell,null,"color"),pe.default.createElement(ge.TableCell,null,"accession"),pe.default.createElement(ge.TableCell,null,"name"),pe.default.createElement(ge.TableCell,null,"count"),pe.default.createElement(ge.TableCell,null,"description"))),pe.default.createElement(ge.TableBody,null,[...t.values()].map(({accession:i,name:s,description:a})=>pe.default.createElement(ge.TableRow,{key:i},pe.default.createElement(ge.TableCell,{padding:"checkbox"},pe.default.createElement(ge.Checkbox,{checked:e.featureFilters.get(i)??!1,onChange:()=>{e.setFilter(i,!e.featureFilters.get(i))}})),pe.default.createElement(ge.TableCell,null,pe.default.createElement("div",{style:{width:20,height:20,background:n[i]}})),pe.default.createElement(ge.TableCell,null,i),pe.default.createElement(ge.TableCell,null,s),pe.default.createElement(ge.TableCell,null,o.get(i)),pe.default.createElement(ge.TableCell,null,a))))))}),EU=(0,ld.observer)(function({onClose:e,model:t}){return pe.default.createElement(eR.Dialog,{onClose:()=>{e()},open:!0,title:"Feature filters",maxWidth:"xl"},pe.default.createElement(ge.DialogContent,null,pe.default.createElement(bU,{model:t})))}),wU=EU});function IU(e){return typeof e=="string"?e:e?.message}async function nl(e,t,r=nR.fetchAndMaybeUnzipText){let n=new AbortController;try{return await r(e,{signal:n.signal,statusCallback:o=>{let i=IU(o);t(i?{msg:i,onCancel:()=>{n.abort()}}:void 0)}})}finally{t(void 0)}}async function oR(e,t){let r=await fetch(e,t);if(!r.ok)throw new Error(`HTTP ${r.status} fetching ${e} ${await r.text()}`);return r}async function l0(e,t){return(await oR(e,t)).text()}async function ud(e,t){return(await oR(e,t)).json()}function iR(e,t){return new Promise((r,n)=>{if(t?.aborted)n(new DOMException("Aborted","AbortError"));else{let o=setTimeout(r,e);t?.addEventListener("abort",()=>{clearTimeout(o),n(new DOMException("Aborted","AbortError"))})}})}function Qo(e){return e instanceof DOMException&&e.name==="AbortError"}var nR,fd=m(()=>{nR=p(we(),1)});var cR={};Bt(cR,{default:()=>vU});var Qe,sR,u0,Oe,aR,SU,vU,lR=m(()=>{Qe=p(Q(),1),sR=p(Ze(),1),u0=p(we(),1),Oe=p(U(),1),aR=p(W(),1);fd();SU=(0,aR.observer)(function({handleClose:e,model:t}){let[r,n]=(0,Qe.useState)(),[o,i]=(0,Qe.useState)("file"),[s,a]=(0,Qe.useState)("");return Qe.default.createElement(sR.Dialog,{maxWidth:"xl",title:"Open protein domains from file",onClose:()=>{e()},open:!0},Qe.default.createElement(Oe.DialogContent,null,Qe.default.createElement("div",null,Qe.default.createElement(Oe.Typography,null,"Open a JSON file of InterProScan results that you run remotely on EBI servers or locally"),Qe.default.createElement("div",{style:{display:"flex",margin:30}},Qe.default.createElement(Oe.FormControl,{component:"fieldset"},Qe.default.createElement(Oe.RadioGroup,{value:o,onChange:c=>{i(c.target.value)}},Qe.default.createElement(Oe.FormControlLabel,{value:"url",control:Qe.default.createElement(Oe.Radio,null),label:"URL"}),Qe.default.createElement(Oe.FormControlLabel,{value:"file",control:Qe.default.createElement(Oe.Radio,null),label:"File"}))),o==="url"?Qe.default.createElement("div",null,Qe.default.createElement(Oe.Typography,null,"Open a InterProScan JSON file remote URL"),Qe.default.createElement(Oe.TextField,{label:"URL",value:s,onChange:c=>{a(c.target.value)}})):null,o==="file"?Qe.default.createElement("div",{style:{paddingTop:20}},Qe.default.createElement(Oe.Typography,null,"Open a InterProScan JSON file file from your local drive"),Qe.default.createElement(Oe.Button,{variant:"outlined",component:"label"},"Choose File",Qe.default.createElement("input",{type:"file",hidden:!0,onChange:({target:c})=>{let l=c.files?.[0];l&&n(l)}}))):null))),Qe.default.createElement(Oe.DialogActions,null,Qe.default.createElement(Oe.Button,{variant:"contained",color:"primary",onClick:()=>{(async()=>{try{let c=r?JSON.parse(await r.text()):await ud(s);t.setDomains(Object.fromEntries(c.results.map(l=>[l.xref[0].id,l]))),(0,u0.getSession)(t).notify("Loaded interproscan results","success")}catch(c){console.error(c),(0,u0.getSession)(t).notifyError(`${c}`,c)}finally{t.setStatus()}})(),e()}},"Open results")))}),vU=SU});function ma(e,t="node",r=0){let n=`${t}-${r}`;return{...e,id:n,name:e.name||n,children:e.children?.map((o,i)=>ma(o,`${n}-${i}`,r+1))||[]}}var f0=m(()=>{});var dr,pa=m(()=>{dr=class{getTree(){return{id:"root",name:"root",noTree:!0,children:this.getNames().map(t=>({id:t,children:[],name:t}))}}getRowData(t){}getStructures(){return{}}getHeader(){return{}}get alignmentNames(){return[]}get seqConsensus(){}get secondaryStructureConsensus(){}get tracks(){return[]}}});function ga(e){return e>=BU&&e<=TU}var uR,fR,BU,TU,dR,AR,eo,d0=m(()=>{pa();uR=65,fR=90,BU=97,TU=122,dR=45,AR=46;eo=class extends dr{MSA;orderedNames;constructor(t){super();let r=[],n=[];for(let o of t.split(">")){if(!/\S/.test(o))continue;let i=o.indexOf(`
-`);if(i===-1)continue;let s=o.slice(0,i).replace(/\r$/,""),a=s.indexOf(" "),c=a===-1?s:s.slice(0,a);c&&(r.push(o.slice(i+1).replaceAll(/\s/g,"")),n.push(c))}this.orderedNames=n,this.MSA={seqdata:this.expandA3M(r,n)}}static sniff(t){if(!t.startsWith(">"))return!1;let r=[];for(let s of t.split(">")){if(!/\S/.test(s))continue;let a=s.indexOf(`
-`);if(a===-1)continue;let c=s.slice(a+1).replaceAll(/\s/g,"");c&&r.push(c)}if(r.length<2||new Set(r.map(s=>s.length)).size===1)return!1;let n=!1,o=-1,i=!0;for(let s of r){let a=0;for(let c=0;c<s.length;c++){let l=s.charCodeAt(c);ga(l)?n=!0:(l>=uR&&l<=fR||l===dR)&&a++}o===-1?o=a:a!==o&&(i=!1)}return n&&i}expandA3M(t,r){let n=r.length;if(n===0)return{};let o=[],i=[];for(let l=0;l<n;l++){let u=t[l],d=[],A=[],f=0;for(;f<u.length;){let g=u.charCodeAt(f);if(g>=uR&&g<=fR||g===dR){d.push(u[f]);let h="",y=f+1;for(;y<u.length;){let E=u.charCodeAt(y);if(ga(E)||E===AR)h+=u[y],y++;else break}A.push(h),f=y}else if(g===AR)f++;else if(ga(g)){let h="";for(;f<u.length&&ga(u.charCodeAt(f));)h+=u[f],f++;d.push(""),A.push(h)}else f++}o.push(d),i.push(A)}let s=Math.max(...o.map(l=>l.length),0),a=new Array(s).fill(0);for(let l=0;l<n;l++){let u=i[l];for(let d=0;d<u.length;d++){let A=0;for(let f of u[d])ga(f.charCodeAt(0))&&A++;A>a[d]&&(a[d]=A)}}let c={};for(let l=0;l<n;l++){let u=o[l],d=i[l],A=[];for(let f=0;f<s;f++){let g=a[f];if(f<u.length){let h=u[f],y=d[f]||"";A.push(h||"-");let E="";for(let S of y)ga(S.charCodeAt(0))&&(E+=S.toUpperCase());A.push(E);let x=g-E.length;x>0&&A.push(".".repeat(x))}else A.push("-"),g>0&&A.push(".".repeat(g))}c[r[l]]=A.join("")}return c}getMSA(){return this.MSA}getNames(){return this.orderedNames}getRow(t){return this.MSA.seqdata[t]||""}getWidth(){let t=Object.keys(this.MSA.seqdata)[0];return t?this.getRow(t).length:0}}});function MU(e){let t=/\(?(\d+(\.\d+)+)\)?/.exec(e);return t&&t.length>1?t[1]:""}function pR(e){let t=["CLUSTAL","PROBCONS","MUSCLE","MSAPROBS","Kalign"];t.some(n=>e.startsWith(n))||console.warn(`${e} is not a known CLUSTAL header: ${t.join(",")}, proceeding but could indicate an issue`);let r=MU(e);return{info:e,version:r}}function A0(e){let t=e.next();for(;!t.done&&t.value.trim()==="";)t=e.next();return t.value}function RU(e){let t=e.split(/\s+/),r=e.slice(t[0].length),n=t[0].length+r.indexOf(t[1]),o=n+t[1].length;return[n,o]}function mR(e){let t=A0(e),r=[],n="";if(!t)return;for(;t;)t.startsWith(" ")?n=t:r.push(t),t=e.next().value;let[o,i]=RU(r[0]),a=r.map(d=>d.split(/\s+/)).map(d=>d[0]),c=r.map(d=>d.slice(o,i)),l=n.slice(o,i),u=c[0].length-l.length;return u&&(l+=" ".repeat(u)),{ids:a,seqs:c,consensus:l}}function gR(e){let t,r=mR(e);if(r!==void 0)for(;t=mR(e);){for(let n=0;n<t.seqs.length;n++)r.seqs[n]+=t.seqs[n];r.consensus+=t.consensus}return r}var hR=m(()=>{});function QU(e){let t=A0(e);if(!t)throw new Error("Empty file received");let r=pR(t),n=gR(e);if(n===void 0)throw new Error("No blocks parsed");let o=n.seqs.map((s,a)=>({id:n.ids[a],seq:s})),{consensus:i}=n;if(i.length!==o[0].seq.length)throw new Error(`Consensus length != sequence length. Con ${i.length} seq ${o[0].seq.length}`);return{consensus:i,alns:o,header:r}}function yR(e){let t=e.split(`
-`)[Symbol.iterator]();return QU(t)}var xR=m(()=>{hR()});var _o,m0=m(()=>{xR();pa();_o=class extends dr{MSA;constructor(t){super(),this.MSA=yR(t)}getMSA(){return this.MSA}getRow(t){return this.MSA.alns.find(r=>r.id===t)?.seq??""}getWidth(){return this.MSA.alns[0]?.seq.length??0}getHeader(){return this.MSA.header}getNames(){return this.MSA.alns.map(t=>t.id)}get seqConsensus(){return this.MSA.consensus}}});function CR(e){let t=e.split(`
-`).map(i=>i.trim()).filter(i=>!!i),r=[],n=[];for(let i of t)if(i.startsWith("SEQ"))r.push(i);else{if(i.startsWith("DATA"))continue;if(i.startsWith("//"))break;n.push(i)}let o=r.map(i=>{let[,s,a,c,l,u,d,A,f]=i.split(" ");return{species:s,protein:a,chr:c,start:+l,end:+u,strand:+d,geneId:A,unknown:f,seq:""}});for(let i of n)for(let s=0;s<r.length;s++)o[s].seq+=i[s];return o}function dd(e){let t=e.split(`
-`).map(i=>i.trim()).filter(i=>!!i),r=[],n="";for(let i of t)if(i.startsWith("SEQ"))r.push(i);else{if(i.startsWith("DATA"))continue;if(i.startsWith("//"))break;n=i}let o=r.map(i=>{let[,s,a,c,l,u,d,A,f]=i.split(" ");return{species:s,protein:a,chr:c,start:+l,end:+u,strand:+d,geneId:A,unknown:f}});return{tree:n,seqs:o}}var p0=m(()=>{});var ko,g0=m(()=>{p0();pa();ko=class extends dr{MSA;constructor(t){super(),this.MSA=CR(t)}getMSA(){return this.MSA}getRow(t){return this.MSA.find(r=>r.protein===t)?.seq??""}getWidth(){return this.MSA[0]?.seq.length??0}getNames(){return this.MSA.map(t=>t.protein)}}});var Do,h0=m(()=>{pa();Do=class extends dr{MSA;orderedNames=[];constructor(t){super();let r={},n={};for(let o of t.split(">")){if(!/\S/.test(o))continue;let i=o.indexOf(`
-`);if(i===-1)continue;let s=o.slice(0,i).replace(/\r$/,""),a=s.indexOf(" "),c=a===-1?s:s.slice(0,a);c&&(r[c]=o.slice(i+1).replaceAll(/\s/g,""),this.orderedNames.push(c),c.includes(":")&&(n[c.replaceAll(":","_")]=c))}this.MSA={seqdata:r,colonNormalized:n}}getMSA(){return this.MSA}getNames(){return this.orderedNames}getRow(t){return this.MSA.seqdata[t]??this.MSA.seqdata[this.MSA.colonNormalized[t]??""]??""}getWidth(){let t=this.orderedNames[0];return t===void 0?0:this.getRow(t).length}}});function Mi(e){let t=[],r=[],n=e.replace(/'((?:[^']|'')*)'/g,(s,a)=>{let c=r.length;return r.push(a.replaceAll("''","'")),`__Q${c}__`}),o={},i=n.split(/\s*(;|\(|\)|,|:)\s*/);for(let s=0;s<i.length;s++){let c=i[s].replace(/^__Q(\d+)__$/,(u,d)=>r[Number(d)]),l={};switch(c){case"(":o.children=[l],t.push(o),o=l;break;case",":t.at(-1)?.children.push(l),o=l;break;case")":o=t.pop();break;case":":break;default:{let u=i[s-1];u===")"||u==="("||u===","?o.name=c:u===":"&&(o.length=Number.parseFloat(c))}}}return o}var y0=m(()=>{});function bR(){return{gf:{},gc:{},gs:{},gr:{},seqname:[],seqdata:{}}}function ol(e,t){if(e)return e;if(t)throw new Error("No format header: # STOCKHOLM 1.0");return bR()}function il(e){return ER.test(e)}function wR(e,t){let r=t??{},n=[],o=null,i=e.split(`
-`);for(let s of i){let a;if(ER.test(s))o=bR();else if(_U.test(s))o&&n.push(o),o=null;else if(a=kU.exec(s)){o=ol(o,!!r.strict);let c=a[1];o.gf[c]||(o.gf[c]=[]),o.gf[c].push(a[2])}else if(a=DU.exec(s)){o=ol(o,!!r.strict);let c=a[1];o.gc[c]||(o.gc[c]=""),o.gc[c]+=a[2]}else if(a=NU.exec(s)){o=ol(o,!!r.strict);let c=a[1],l=a[2],u=a[3];o.gs[l]||(o.gs[l]={}),o.gs[l][c]||(o.gs[l][c]=[]),o.gs[l][c].push(u)}else if(a=LU.exec(s)){o=ol(o,!!r.strict);let c=a[1],l=a[2],u=a[3];o.gr[l]||(o.gr[l]={}),o.gr[l][c]||(o.gr[l][c]=""),o.gr[l][c]+=u}else if(a=PU.exec(s)){o=ol(o,!!r.strict);let c=a[1],l=a[2];o.seqdata[c]||(o.seqdata[c]="",o.seqname.push(c)),o.seqdata[c]+=l}else if(FU.test(s)&&r.strict)throw new Error("Malformed line")}return o&&n.push(o),n}var ER,_U,kU,DU,NU,LU,PU,FU,x0=m(()=>{ER=/^# STOCKHOLM 1.0/,_U=/^\/\/\s*$/,kU=/^#=GF\s+(\S+)\s+(.*?)\s*$/,DU=/^#=GC\s+(\S+)\s+(.*?)\s*$/,NU=/^#=GS\s+(\S+)\s+(\S+)\s+(.*?)\s*$/,LU=/^#=GR\s+(\S+)\s+(\S+)\s+(.*?)\s*$/,PU=/^\s*(\S+)\s+(\S+)\s*$/,FU=/\S/});var No,C0=m(()=>{f0();pa();y0();x0();x0();No=class extends dr{data;MSA;constructor(t,r){super();let n=wR(t);this.data=n;let o=n[r]??n[0];if(!o)throw new Error("No alignments found in Stockholm file");this.MSA=o}getMSA(){return this.MSA}getRow(t){return this.MSA.seqdata[t]??""}getWidth(){let t=Object.keys(this.MSA.seqdata)[0];return t===void 0?0:this.getRow(t).length}get alignmentNames(){return this.data.map((t,r)=>t.gf.DE?.[0]??`Alignment ${r+1}`)}getHeader(){let t=this.MSA.gs.AC??{},r=this.MSA.gs.DR??{};return{General:this.MSA.gf,Accessions:Object.fromEntries(Object.entries(t).map(([n,o])=>[n,o[0]])),Dbxref:Object.fromEntries(Object.entries(r).map(([n,o])=>[n,o.join("; ")]))}}getRowData(t){return{name:t,accession:this.MSA.gs.AC?.[t]?.[0],dbxref:this.MSA.gs.DR?.[t]?.join("; ")}}getNames(){return Object.keys(this.MSA.seqdata)}getStructures(){let t=/PDB; +(\S+) +(\S); ([0-9]+)-([0-9]+)/,r=this.MSA.gs.DR??{},n={};for(let[o,i]of Object.entries(r))for(let s of i){let a=t.exec(s);a&&(n[o]??=[]).push({pdb:a[1].toLowerCase(),chain:a[2],startPos:+a[3],endPos:+a[4]})}return n}getTree(){let t=this.MSA.gf.NH?.[0];return t?ma(Mi(t)):super.getTree()}get seqConsensus(){return this.MSA.gc.seq_cons}get secondaryStructureConsensus(){return this.MSA.gc.SS_cons}get tracks(){return[{id:"seqConsensus",name:"Sequence consensus",data:this.seqConsensus,customColorScheme:{}},{id:"secondaryStruct",name:"Secondary-structure",data:this.secondaryStructureConsensus,customColorScheme:{"<":"lightblue","(":"lightblue","[":"lightblue","{":"lightblue",">":"pink",")":"pink","]":"pink","}":"pink"}}]}}});function b0(e,t=0,r){return r==="stockholm"?new No(e,t):r==="a3m"?new eo(e):r==="fasta"?new Do(e):r==="emf"?new ko(e):r==="clustal"?new _o(e):il(e)?new No(e,t):eo.sniff(e)?new eo(e):e.startsWith(">")?new Do(e):e.startsWith("SEQ")?new ko(e):new _o(e)}function E0(e){return e.replaceAll(/[.-]/g,"")}var IR=m(()=>{d0();m0();g0();h0();C0();p0();y0();d0();m0();g0();h0();C0()});function OU(e){try{return decodeURIComponent(e)}catch{return e}}function GU(e){return e?Object.fromEntries(e.split(";").map(t=>t.trim()).filter(t=>!!t).map(t=>{let r=t.indexOf("="),n=(r===-1?t:t.slice(0,r)).trim(),o=r===-1?void 0:t.slice(r+1);return[n,o?o.split(",").map(i=>OU(i).trim()).join(" "):void 0]}).filter(([t])=>t!=="")):{}}function Ad(e){return e?e.split(`
-`).map(t=>t.trim()).filter(t=>!!t&&!t.startsWith("#")).map(t=>{let r=t.split("	"),[n,o,i,s,a,c,l,u]=r,d=r[8];return{seq_id:n??"",source:o??"",type:i??"",start:Number(s)||0,end:Number(a)||0,score:Number(c)||0,strand:l??".",phase:u??".",...GU(d)}}):[]}var SR=m(()=>{});function HU({type:e,strand:t}){let r=t==="+"?1:t==="-"?-1:void 0;return UU.has(e)?r:void 0}function md(e){let t=new Map;for(let n of e){let o=t.get(n.seq_id);o?o.push(n):t.set(n.seq_id,[n])}let r={};for(let[n,o]of t){let i=new Map,s=new Map;for(let c of o){let l=c.Name||c.ID||`${c.source}_${c.start}_${c.end}`,u=c.signature_desc||c.Name||l,d=c.Ontology_term||c.description||c.Note||u;s.has(l)||s.set(l,{name:u,description:d,accession:l,featureType:c.type});let A={start:c.start,end:c.end,strand:HU(c)},f=i.get(l);f?f.push(A):i.set(l,[A])}let a=[];for(let[c,l]of i){let u=s.get(c);a.push({signature:{entry:u},locations:l})}r[n]={matches:a,xref:[{id:n}]}}return r}var UU,vR=m(()=>{UU=new Set(["gene","pseudogene","mRNA","transcript","primary_transcript","ncRNA","tRNA","rRNA","snRNA","snoRNA","miRNA","lnc_RNA"])});var BR=m(()=>{});var TR=m(()=>{SR();vR();BR()});var w0=m(()=>{f0();IR();TR()});async function WU({seq:e,onProgress:t,onJobId:r,programs:n,model:o,signal:i}){let s=await l0(`${I0}/iprscan5/run`,{method:"POST",body:new URLSearchParams({email:"colin.diesh@gmail.com",sequence:e,programs:n.join(",")}),signal:i});r?.(s),await qU({jobId:s,onProgress:t,signal:i}),await zU({jobId:s,model:o,onProgress:t,signal:i})}function YU(e,t){return ud(`${I0}/iprscan5/result/${e}/json`,{signal:t})}async function qU({onProgress:e,jobId:t,signal:r}){let n=`${I0}/iprscan5/status/${t}`,o=360;try{let i=!1;for(let s=0;s<o&&!i;s++){for(let c=0;c<10;c++)await iR(1e3,r),e({msg:`Checking status ${10-c}`,url:n});let a=(await l0(n,{signal:r})).trim();if(a==="FINISHED")i=!0;else if(a==="FAILURE"||a==="ERROR"||a==="NOT_FOUND")throw new Error(`InterProScan job ${t} ended with status: ${a}`)}if(!i)throw new Error(`InterProScan job ${t} did not finish after ${o} status checks`)}finally{e()}}async function MR({algorithm:e,seq:t,programs:r,onJobId:n,onProgress:o,model:i,signal:s}){try{if(o({msg:`Launching ${e} MSA`}),e==="interproscan")await WU({seq:t,onJobId:n,onProgress:o,programs:r,model:i,signal:s});else throw new Error("unknown algorithm")}catch(a){if(Qo(a))(0,sl.getSession)(i).notify("Cancelled InterProScan query","info");else throw a}finally{o()}}async function zU({jobId:e,model:t,onProgress:r,signal:n}){try{r({msg:`Downloading results of ${e} (for larger sequences this can be slow, click status to download and upload in the manual tab)`,url:`https://www.ebi.ac.uk/Tools/services/rest/iprscan5/result/${e}/json`});let o=await YU(e,n);t.setDomains(Object.fromEntries(o.results.map(i=>[i.xref[0]?.id,i]).filter(i=>i[0]!==void 0))),(0,sl.getSession)(t).notify(`Loaded interproscan ${e} results`,"success")}catch(o){Qo(o)?(0,sl.getSession)(t).notify("Cancelled InterProScan query","info"):(console.error(o),(0,sl.getSession)(t).notifyError(`${o}`,o))}finally{r()}}var sl,I0,RR=m(()=>{sl=p(we(),1);fd();I0="https://www.ebi.ac.uk/Tools/services/rest"});var DR={};Bt(DR,{default:()=>KU});var Ge,QR,_R,Ar,kR,JU,KU,NR=m(()=>{Ge=p(Q(),1),QR=p(Ze(),1),_R=p(we(),1),Ar=p(U(),1),kR=p(W(),1);w0();RR();JU=(0,kR.observer)(function({handleClose:e,model:t}){let[r,n]=(0,Ge.useState)([{name:"NCBIfam",description:"NCBI RefSeq FAMs including TIGRFAMs",category:"Families, domains, sites & repeats",checked:!0},{name:"SFLD",description:"Structure function linkage database",category:"Families, domains, sites & repeats",checked:!0},{name:"Phobius",checked:!0,description:"A combined transmembrane topology and signal peptide predictor",category:"Other sequence features"},{name:"SignalP",checked:!0,category:"Other sequence features"},{name:"SignalP_EUK",category:"Other category",checked:!0},{name:"SignalP_GRAM_POSITIVE",category:"Other category",checked:!0},{name:"SignalP_GRAM_NEGATIVE",checked:!0,category:"Other category"},{name:"SuperFamily",category:"Structural domains",checked:!0},{name:"Panther",category:"Families, domains, sites & repeats",checked:!0},{name:"Gene3d",category:"Structural domains",checked:!0},{name:"HAMAP",category:"Families, domains, sites & repeats",checked:!0},{name:"PrositeProfiles",category:"Families, domains, sites & repeats",checked:!0},{name:"PrositePatterns",category:"Families, domains, sites & repeats",checked:!0},{name:"Coils",category:"Other sequence features",checked:!0},{name:"SMART",category:"Families, domains, sites & repeats",checked:!0},{name:"CDD",description:"Conserved Domains Database",category:"Families, domains, sites & repeats",checked:!0},{name:"PRINTS",category:"Families, domains, sites & repeats",checked:!0},{name:"PfamA",category:"Families, domains, sites & repeats",checked:!0},{name:"MobiDBLite",checked:!0,category:"Other sequence features"},{name:"PIRSF",checked:!0,category:"Other category"},{name:"TMHMM",checked:!0,category:"Other sequence features"},{name:"AntiFam",checked:!0,category:"Other category"},{name:"FunFam",checked:!0,category:"Other category"},{name:"PIRSR",checked:!0,category:"Families, domains, sites & repeats"}]),o=r.filter(a=>a.checked).map(a=>a.name),[i,s]=(0,Ge.useState)(!1);return Ge.default.createElement(QR.Dialog,{maxWidth:"xl",title:"Query InterProScan API for domains",onClose:()=>{e()},open:!0},Ge.default.createElement(Ar.DialogContent,null,Ge.default.createElement(Ar.Typography,null,"This will run InterProScan via the InterProScan API on all rows of the current MSA"),Ge.default.createElement(Ar.Button,{onClick:()=>{s(!i)}},i?"Hide":"Show"," advanced options"),i?Ge.default.createElement("div",null,Ge.default.createElement(Ar.Typography,null,"Select algorithms for InterProScan to run"),Ge.default.createElement("div",null,Ge.default.createElement(Ar.Button,{variant:"contained",color:"secondary",onClick:()=>{n(r.map(a=>({...a,checked:!1})))}},"Select none"),Ge.default.createElement(Ar.Button,{variant:"contained",color:"primary",onClick:()=>{n(r.map(a=>({...a,checked:!0})))}},"Select all")),Ge.default.createElement("table",null,Ge.default.createElement("tbody",null,r.toSorted((a,c)=>a.category.localeCompare(c.category)).map(({name:a,checked:c,category:l})=>Ge.default.createElement("tr",{key:a},Ge.default.createElement("td",null,Ge.default.createElement("input",{type:"checkbox",key:a,checked:c,onChange:()=>{n(r.map(u=>u.name===a?{...u,checked:!u.checked}:u))}})),Ge.default.createElement("td",null,a),Ge.default.createElement("td",null,l)))))):null),Ge.default.createElement(Ar.DialogActions,null,Ge.default.createElement(Ar.Button,{variant:"contained",color:"secondary",onClick:()=>{e()}},"Cancel"),Ge.default.createElement(Ar.Button,{variant:"contained",color:"primary",onClick:()=>{let a=new AbortController;(async()=>{try{let{rows:c}=t;if(c.length>140)throw new Error("Too many sequences, please run InterProScan offline");await MR({algorithm:"interproscan",programs:o,seq:c.map(l=>[l[0],E0(l[1])]).filter(l=>!!l[1]).map(l=>`>${l[0]}
+  `):"",this.name="UnsubscriptionError",this.errors=r}})});function Mh(e,t){if(e){var r=e.indexOf(t);0<=r&&e.splice(r,1)}}var qB=m(()=>{});function JB(e){return e instanceof ad||e&&"closed"in e&&yn(e.remove)&&yn(e.add)&&yn(e.unsubscribe)}function zB(e){yn(e)?e():e.unsubscribe()}var ad,_oe,KB=m(()=>{el();od();YB();qB();ad=(function(){function e(t){this.initialTeardown=t,this.closed=!1,this._parentage=null,this._finalizers=null}return e.prototype.unsubscribe=function(){var t,r,n,o,i;if(!this.closed){this.closed=!0;var s=this._parentage;if(s)if(this._parentage=null,Array.isArray(s))try{for(var a=Bh(s),c=a.next();!c.done;c=a.next()){var l=c.value;l.remove(this)}}catch(h){t={error:h}}finally{try{c&&!c.done&&(r=a.return)&&r.call(a)}finally{if(t)throw t.error}}else s.remove(this);var u=this.initialTeardown;if(yn(u))try{u()}catch(h){i=h instanceof sd?h.errors:[h]}var d=this._finalizers;if(d){this._finalizers=null;try{for(var A=Bh(d),f=A.next();!f.done;f=A.next()){var g=f.value;try{zB(g)}catch(h){i=i??[],h instanceof sd?i=aa(aa([],sa(i)),sa(h.errors)):i.push(h)}}}catch(h){n={error:h}}finally{try{f&&!f.done&&(o=A.return)&&o.call(A)}finally{if(n)throw n.error}}}if(i)throw new sd(i)}},e.prototype.add=function(t){var r;if(t&&t!==this)if(this.closed)zB(t);else{if(t instanceof e){if(t.closed||t._hasParent(this))return;t._addParent(this)}(this._finalizers=(r=this._finalizers)!==null&&r!==void 0?r:[]).push(t)}},e.prototype._hasParent=function(t){var r=this._parentage;return r===t||Array.isArray(r)&&r.includes(t)},e.prototype._addParent=function(t){var r=this._parentage;this._parentage=Array.isArray(r)?(r.push(t),r):r?[r,t]:t},e.prototype._removeParent=function(t){var r=this._parentage;r===t?this._parentage=null:Array.isArray(r)&&Mh(r,t)},e.prototype.remove=function(t){var r=this._finalizers;r&&Mh(r,t),t instanceof e&&t._removeParent(this)},e.EMPTY=(function(){var t=new e;return t.closed=!0,t})(),e})(),_oe=ad.EMPTY});var Eo,cd=m(()=>{Eo={onUnhandledError:null,onStoppedNotification:null,Promise:void 0,useDeprecatedSynchronousErrorHandling:!1,useDeprecatedNextContext:!1}});var ca,Rh=m(()=>{el();ca={setTimeout:function(e,t){for(var r=[],n=2;n<arguments.length;n++)r[n-2]=arguments[n];var o=ca.delegate;return o?.setTimeout?o.setTimeout.apply(o,aa([e,t],sa(r))):setTimeout.apply(void 0,aa([e,t],sa(r)))},clearTimeout:function(e){var t=ca.delegate;return(t?.clearTimeout||clearTimeout)(e)},delegate:void 0}});function XB(e){ca.setTimeout(function(){var t=Eo.onUnhandledError;if(t)t(e);else throw e})}var ZB=m(()=>{cd();Rh()});function Qh(){}var eT=m(()=>{});function rT(e){return _h("E",void 0,e)}function nT(e){return _h("N",e,void 0)}function _h(e,t,r){return{kind:e,value:t,error:r}}var tT,oT=m(()=>{tT=(function(){return _h("C",void 0,void 0)})()});function iT(e){Eo.useDeprecatedSynchronousErrorHandling&&kh&&(kh.errorThrown=!0,kh.error=e)}var kh,sT=m(()=>{cd();kh=null});function Dh(e,t){return w6.call(e,t)}function ld(e){Eo.useDeprecatedSynchronousErrorHandling?iT(e):XB(e)}function S6(e){throw e}function Nh(e,t){var r=Eo.onStoppedNotification;r&&ca.setTimeout(function(){return r(e,t)})}var Lh,w6,I6,Fh,v6,Ph=m(()=>{el();od();KB();cd();ZB();eT();oT();Rh();sT();Lh=(function(e){Zc(t,e);function t(r){var n=e.call(this)||this;return n.isStopped=!1,r?(n.destination=r,JB(r)&&r.add(n)):n.destination=v6,n}return t.create=function(r,n,o){return new Fh(r,n,o)},t.prototype.next=function(r){this.isStopped?Nh(nT(r),this):this._next(r)},t.prototype.error=function(r){this.isStopped?Nh(rT(r),this):(this.isStopped=!0,this._error(r))},t.prototype.complete=function(){this.isStopped?Nh(tT,this):(this.isStopped=!0,this._complete())},t.prototype.unsubscribe=function(){this.closed||(this.isStopped=!0,e.prototype.unsubscribe.call(this),this.destination=null)},t.prototype._next=function(r){this.destination.next(r)},t.prototype._error=function(r){try{this.destination.error(r)}finally{this.unsubscribe()}},t.prototype._complete=function(){try{this.destination.complete()}finally{this.unsubscribe()}},t})(ad),w6=Function.prototype.bind;I6=(function(){function e(t){this.partialObserver=t}return e.prototype.next=function(t){var r=this.partialObserver;if(r.next)try{r.next(t)}catch(n){ld(n)}},e.prototype.error=function(t){var r=this.partialObserver;if(r.error)try{r.error(t)}catch(n){ld(n)}else ld(t)},e.prototype.complete=function(){var t=this.partialObserver;if(t.complete)try{t.complete()}catch(r){ld(r)}},e})(),Fh=(function(e){Zc(t,e);function t(r,n,o){var i=e.call(this)||this,s;if(yn(r)||!r)s={next:r??void 0,error:n??void 0,complete:o??void 0};else{var a;i&&Eo.useDeprecatedNextContext?(a=Object.create(r),a.unsubscribe=function(){return i.unsubscribe()},s={next:r.next&&Dh(r.next,a),error:r.error&&Dh(r.error,a),complete:r.complete&&Dh(r.complete,a)}):s=r}return i.destination=new I6(s),i}return t})(Lh);v6={closed:!0,next:Qh,error:S6,complete:Qh}});function B6(e){return yn(e?.lift)}function ud(e){return function(t){if(B6(t))return t.lift(function(r){try{return e(r,this)}catch(n){this.error(n)}});throw new TypeError("Unable to lift unknown Observable type")}}var Oh=m(()=>{od()});function aT(e,t,r,n,o){return new T6(e,t,r,n,o)}var T6,cT=m(()=>{el();Ph();T6=(function(e){Zc(t,e);function t(r,n,o,i,s,a){var c=e.call(this,r)||this;return c.onFinalize=s,c.shouldUnsubscribe=a,c._next=n?function(l){try{n(l)}catch(u){r.error(u)}}:e.prototype._next,c._error=i?function(l){try{i(l)}catch(u){r.error(u)}finally{this.unsubscribe()}}:e.prototype._error,c._complete=o?function(){try{o()}catch(l){r.error(l)}finally{this.unsubscribe()}}:e.prototype._complete,c}return t.prototype.unsubscribe=function(){var r;if(!this.shouldUnsubscribe||this.shouldUnsubscribe()){var n=this.closed;e.prototype.unsubscribe.call(this),!n&&((r=this.onFinalize)===null||r===void 0||r.call(this))}},t})(Lh)});var lT,uT=m(()=>{Th();lT=id(function(e){return function(){e(this),this.name="EmptyError",this.message="no elements in sequence"}})});function Gh(e,t){var r=typeof t=="object";return new Promise(function(n,o){var i=new Fh({next:function(s){n(s),i.unsubscribe()},error:o,complete:function(){r?n(t.defaultValue):o(new lT)}});e.subscribe(i)})}var fT=m(()=>{uT();Ph()});var dT=m(()=>{});function AT(e,t,r,n,o){return function(i,s){var a=r,c=t,l=0;i.subscribe(aT(s,function(u){var d=l++;c=a?e(c,u,d):(a=!0,u),n&&s.next(c)},o&&(function(){a&&s.next(c),s.complete()})))}}var mT=m(()=>{cT()});function pT(e,t){return ud(AT(e,t,arguments.length>=2,!1,!0))}var gT=m(()=>{mT();Oh()});function Uh(){return ud(function(e,t){pT(M6,[])(e).subscribe(t)})}var M6,hT=m(()=>{gT();Oh();M6=function(e,t){return e.push(t),e}});var yT=m(()=>{fT();dT();hT()});var xT=m(()=>{});var CT=m(()=>{});function R6(){return ET||(ET=[IDBDatabase,IDBObjectStore,IDBIndex,IDBCursor,IDBTransaction])}function Q6(){return bT||(bT=[IDBCursor.prototype.advance,IDBCursor.prototype.continue,IDBCursor.prototype.continuePrimaryKey])}function _6(e){let t=new Promise((r,n)=>{let o=()=>{e.removeEventListener("success",i),e.removeEventListener("error",s)},i=()=>{r(Ii(e.result)),o()},s=()=>{n(e.error),o()};e.addEventListener("success",i),e.addEventListener("error",s)});return fd.set(t,e),t}function k6(e){if($h.has(e))return;let t=new Promise((r,n)=>{let o=()=>{e.removeEventListener("complete",i),e.removeEventListener("error",s),e.removeEventListener("abort",s)},i=()=>{r(),o()},s=()=>{n(e.error||new DOMException("AbortError","AbortError")),o()};e.addEventListener("complete",i),e.addEventListener("error",s),e.addEventListener("abort",s)});$h.set(e,t)}function vT(e){Wh=e(Wh)}function D6(e){return Q6().includes(e)?function(...t){return e.apply(Yh(this),t),Ii(this.request)}:function(...t){return Ii(e.apply(Yh(this),t))}}function N6(e){return typeof e=="function"?D6(e):(e instanceof IDBTransaction&&k6(e),jh(e,R6())?new Proxy(e,Wh):e)}function Ii(e){if(e instanceof IDBRequest)return _6(e);if(Hh.has(e))return Hh.get(e);let t=N6(e);return t!==e&&(Hh.set(e,t),fd.set(t,e)),t}function zh(e,t,{blocked:r,upgrade:n,blocking:o,terminated:i}={}){let s=indexedDB.open(e,t),a=Ii(s);return n&&s.addEventListener("upgradeneeded",c=>{n(Ii(s.result),c.oldVersion,c.newVersion,Ii(s.transaction),c)}),r&&s.addEventListener("blocked",c=>r(c.oldVersion,c.newVersion,c)),a.then(c=>{i&&c.addEventListener("close",()=>i()),o&&c.addEventListener("versionchange",l=>o(l.oldVersion,l.newVersion,l))}).catch(()=>{}),a}function wT(e,t){if(!(e instanceof IDBDatabase&&!(t in e)&&typeof t=="string"))return;if(Vh.get(t))return Vh.get(t);let r=t.replace(/FromIndex$/,""),n=t!==r,o=F6.includes(r);if(!(r in(n?IDBIndex:IDBObjectStore).prototype)||!(o||L6.includes(r)))return;let i=async function(s,...a){let c=this.transaction(s,o?"readwrite":"readonly"),l=c.store;return n&&(l=l.index(a.shift())),(await Promise.all([l[r](...a),o&&c.done]))[0]};return Vh.set(t,i),i}async function*G6(...e){let t=this;if(t instanceof IDBCursor||(t=await t.openCursor(...e)),!t)return;t=t;let r=new Proxy(t,O6);for(BT.set(r,t),fd.set(r,Yh(t));t;)yield r,t=await(qh.get(r)||t.continue()),qh.delete(r)}function ST(e,t){return t===Symbol.asyncIterator&&jh(e,[IDBIndex,IDBObjectStore,IDBCursor])||t==="iterate"&&jh(e,[IDBIndex,IDBObjectStore])}var jh,ET,bT,$h,Hh,fd,Wh,Yh,L6,F6,Vh,P6,IT,qh,BT,O6,Jh=m(()=>{jh=(e,t)=>t.some(r=>e instanceof r);$h=new WeakMap,Hh=new WeakMap,fd=new WeakMap;Wh={get(e,t,r){if(e instanceof IDBTransaction){if(t==="done")return $h.get(e);if(t==="store")return r.objectStoreNames[1]?void 0:r.objectStore(r.objectStoreNames[0])}return Ii(e[t])},set(e,t,r){return e[t]=r,!0},has(e,t){return e instanceof IDBTransaction&&(t==="done"||t==="store")?!0:t in e}};Yh=e=>fd.get(e);L6=["get","getKey","getAll","getAllKeys","count"],F6=["put","add","delete","clear"],Vh=new Map;vT(e=>({...e,get:(t,r,n)=>wT(t,r)||e.get(t,r,n),has:(t,r)=>!!wT(t,r)||e.has(t,r)}));P6=["continue","continuePrimaryKey","advance"],IT={},qh=new WeakMap,BT=new WeakMap,O6={get(e,t){if(!P6.includes(t))return e[t];let r=IT[t];return r||(r=IT[t]=function(...n){qh.set(this,BT.get(this)[t](...n))}),r}};vT(e=>({...e,get(t,r,n){return ST(t,r)?G6:e.get(t,r,n)},has(t,r){return ST(t,r)||e.has(t,r)}}))});var TT=m(()=>{Jh()});var dd,MT=m(()=>{dd=p(zt(),1)});function Xh(e,t=10){let r=String(e),n=0;for(let o=0,i=r.length;o<i;o++)n+=V6[r.charCodeAt(o)]??j6;return n*t}function Zh(e){let t=0;if(e.length===0)return t;for(let r=0;r<e.length;r++){let n=e.charCodeAt(r);t=(t<<5)-t+n,t|=0}return t}function $6(e){let{uri:t,baseUri:r=""}=e,n;try{n=new URL(t,r).href}catch{n=t}return n}function e0(e){return Br(e)?ed(e)?$6(e):JSON.stringify(e):String(e)}function RT(e){let t=/(^|[\s\n]|<[A-Za-z]*\/?>)((?:https?|ftp):\/\/[-A-Z0-9+\u0026\u2019@#/%?=()~_|!:,.;]*[-A-Z0-9+\u0026@#/%=~()_|])/gi;return e.replaceAll(t,`$1<a href='$2' target="_blank">$2</a>`)}function QT(e,t){let{padding:r=30,minWidth:n=80,fontSize:o=12,maxWidth:i=1e3,stripHTML:s=!1}=t||{};return t0(e.map(a=>e0(a)).map(a=>s?MB(a):a).map(a=>Xh(a,o)).map(a=>Math.min(Math.max(a+r,n),i)))}function t0(e,t=Number.NEGATIVE_INFINITY){let r=t;for(let n of e)r=Math.max(n,r);return r}function Br(e){return typeof e=="object"&&e!==null}var Kh,la,U6,H6,Nie,Lie,Fie,Pie,V6,j6,bo=m(()=>{Kh=p(Q(),1);Ch();la=p(zt(),1),U6=p(Zf(),1),H6=p(TB(),1);Eh();bh();bh();kB();DB();NB();Eh();VB();jB();$B();WB();xT();CT();RB();QB();MT();TT();Nie=180/Math.PI,Lie=Math.PI/180,Fie=/electron/i.test(typeof navigator<"u"?navigator.userAgent:""),Pie=typeof jest>"u"?typeof window<"u"&&window.requestIdleCallback?window.requestIdleCallback:e=>setTimeout(()=>{e()},1):e=>{e()},V6=[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,.2796875,.2765625,.3546875,.5546875,.5546875,.8890625,.665625,.190625,.3328125,.3328125,.3890625,.5828125,.2765625,.3328125,.2765625,.3015625,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.2765625,.2765625,.584375,.5828125,.584375,.5546875,1.0140625,.665625,.665625,.721875,.721875,.665625,.609375,.7765625,.721875,.2765625,.5,.665625,.5546875,.8328125,.721875,.7765625,.665625,.7765625,.721875,.665625,.609375,.721875,.665625,.94375,.665625,.665625,.609375,.2765625,.3546875,.2765625,.4765625,.5546875,.3328125,.5546875,.5546875,.5,.5546875,.5546875,.2765625,.5546875,.5546875,.221875,.240625,.5,.221875,.8328125,.5546875,.5546875,.5546875,.5546875,.3328125,.5,.2765625,.5546875,.5,.721875,.5,.5,.5,.3546875,.259375,.353125,.5890625],j6=.5279276315789471});function _T(e,t){(t==null||t>e.length)&&(t=e.length);for(var r=0,n=Array(t);r<t;r++)n[r]=e[r];return n}function W6(e){if(Array.isArray(e))return e}function Y6(e,t){var r=e==null?null:typeof Symbol<"u"&&e[Symbol.iterator]||e["@@iterator"];if(r!=null){var n,o,i,s,a=[],c=!0,l=!1;try{if(i=(r=r.call(e)).next,t!==0)for(;!(c=(n=i.call(r)).done)&&(a.push(n.value),a.length!==t);c=!0);}catch(u){l=!0,o=u}finally{try{if(!c&&r.return!=null&&(s=r.return(),Object(s)!==s))return}finally{if(l)throw o}}return a}}function q6(){throw new TypeError(`Invalid attempt to destructure non-iterable instance.
+In order to be iterable, non-array objects must have a [Symbol.iterator]() method.`)}function z6(e,t){return W6(e)||Y6(e,t)||J6(e,t)||q6()}function J6(e,t){if(e){if(typeof e=="string")return _T(e,t);var r={}.toString.call(e).slice(8,-1);return r==="Object"&&e.constructor&&(r=e.constructor.name),r==="Map"||r==="Set"?Array.from(e):r==="Arguments"||/^(?:Ui|I)nt(?:8|16|32)(?:Clamped)?Array$/.test(r)?_T(e,t):void 0}}function et(e){return function(t){t instanceof RegExp&&(t.lastIndex=0);for(var r=arguments.length,n=new Array(r>1?r-1:0),o=1;o<r;o++)n[o-1]=arguments[o];return a0(e,t,n)}}function iU(e){return function(){for(var t=arguments.length,r=new Array(t),n=0;n<t;n++)r[n]=arguments[n];return c0(e,r)}}function ne(e,t){let r=arguments.length>2&&arguments[2]!==void 0?arguments[2]:nl;if(kT&&kT(e,null),!Io(t))return e;let n=t.length;for(;n--;){let o=t[n];if(typeof o=="string"){let i=r(o);i!==o&&(K6(t)||(t[n]=i),o=i)}e[o]=!0}return e}function sU(e){for(let t=0;t<e.length;t++)dt(e,t)||(e[t]=null);return e}function Ht(e){let t=da(null);for(let n of YT(e)){var r=z6(n,2);let o=r[0],i=r[1];dt(e,o)&&(Io(i)?t[o]=sU(i):i&&typeof i=="object"&&i.constructor===Object?t[o]=Ht(i):t[o]=i)}return t}function aU(e){switch(typeof e){case"string":return e;case"number":return nU(e);case"boolean":return oU(e);case"bigint":return FT?FT(e):"0";case"symbol":return PT?PT(e):"Symbol()";case"undefined":return rl(e);case"function":case"object":{if(e===null)return rl(e);let t=e,r=xn(t,"toString");if(typeof r=="function"){let n=r(t);return typeof n=="string"?n:rl(n)}return rl(e)}default:return rl(e)}}function xn(e,t){for(;e!==null;){let n=Z6(e,t);if(n){if(n.get)return et(n.get);if(typeof n.value=="function")return et(n.value)}e=X6(e)}function r(){return null}return r}function cU(e){try{return ft(e,""),!0}catch{return!1}}function zT(){let e=arguments.length>0&&arguments[0]!==void 0?arguments[0]:bU(),t=F=>zT(F);if(t.version="3.4.12",t.removed=[],!e||!e.document||e.document.nodeType!==cr.document||!e.Element)return t.isSupported=!1,t;let r=e.document,n=r,o=n.currentScript;e.DocumentFragment;let i=e.HTMLTemplateElement,s=e.Node,a=e.Element,c=e.NodeFilter,l=e.NamedNodeMap;l===void 0&&(e.NamedNodeMap||e.MozNamedAttrMap),e.HTMLFormElement;let u=e.DOMParser,d=e.trustedTypes,A=a.prototype,f=xn(A,"cloneNode"),g=xn(A,"remove"),h=xn(A,"nextSibling"),x=xn(A,"childNodes"),w=xn(A,"parentNode"),y=xn(A,"shadowRoot"),v=xn(A,"attributes"),b=s&&s.prototype?xn(s.prototype,"nodeType"):null,I=s&&s.prototype?xn(s.prototype,"nodeName"):null;if(typeof i=="function"){let F=r.createElement("template");F.content&&F.content.ownerDocument&&(r=F.content.ownerDocument)}let S,B="",R,D=!1,L=0,P=function(){if(L>0)throw Si('A configured TRUSTED_TYPES_POLICY callback (createHTML or createScriptURL) must not call DOMPurify.sanitize, as that causes infinite recursion. Do not pass a policy whose callbacks wrap DOMPurify as TRUSTED_TYPES_POLICY; see the "DOMPurify and Trusted Types" section of the README.')},C=function(E){P(),L++;try{return S.createHTML(E)}finally{L--}},M=function(E){P(),L++;try{return S.createScriptURL(E)}finally{L--}},k=function(){return D||(R=wU(d,o),D=!0),R},G=r,j=G.implementation,oe=G.createNodeIterator,te=G.createDocumentFragment,kr=G.getElementsByTagName,ot=n.importNode,Ae=WT();t.isSupported=typeof YT=="function"&&typeof w=="function"&&j&&j.createHTMLDocument!==void 0;let Dr=fU,mr=dU,nn=AU,Dn=mU,Ji=pU,Nn=gU,io=hU,em=xU,$a=VT,Se=null,Wl=ne({},[...OT,...n0,...o0,...i0,...GT]),_e=null,so=ne({},[...UT,...s0,...HT,...Ad]),ve=Object.seal(da(null,{tagNameCheck:{writable:!0,configurable:!1,enumerable:!0,value:null},attributeNameCheck:{writable:!0,configurable:!1,enumerable:!0,value:null},allowCustomizedBuiltInElements:{writable:!0,configurable:!1,enumerable:!0,value:!1}})),Ki=null,me=null,ae=Object.seal(da(null,{tagCheck:{writable:!0,configurable:!1,enumerable:!0,value:null},attributeCheck:{writable:!0,configurable:!1,enumerable:!0,value:null}})),ke=!0,Be=!0,er=!1,Nt=!0,ye=!1,ze=!0,tr=!1,Ln=!1,Xi=null,Zi=null,It=!1,St=!1,ao=!1,es=!1,ts=!0,Ux=!1,Hx="user-content-",tm=!0,rm=!1,rs={},on=null,nm=ne({},["annotation-xml","audio","colgroup","desc","foreignobject","head","iframe","math","mi","mn","mo","ms","mtext","noembed","noframes","noscript","plaintext","script","selectedcontent","style","svg","template","thead","title","video","xmp"]),Vx=null,jx=ne({},["audio","video","img","source","image","track"]),om=null,$x=ne({},["alt","class","for","id","label","name","pattern","placeholder","role","summary","title","value","style","xmlns"]),Yl="http://www.w3.org/1998/Math/MathML",ql="http://www.w3.org/2000/svg",sn="http://www.w3.org/1999/xhtml",ns=sn,im=!1,sm=null,HP=ne({},[Yl,ql,sn],r0),Wx=Ct(["mi","mo","mn","ms","mtext"]),am=ne({},Wx),Yx=Ct(["annotation-xml"]),cm=ne({},Yx),VP=ne({},["title","style","font","a","script"]),Wa=null,jP=["application/xhtml+xml","text/html"],$P="text/html",Fe=null,os=null,WP=r.createElement("form"),qx=function(E){return E instanceof RegExp||E instanceof Function},lm=function(){let E=arguments.length>0&&arguments[0]!==void 0?arguments[0]:{};if(os&&os===E)return;(!E||typeof E!="object")&&(E={}),E=Ht(E),Wa=jP.indexOf(E.PARSER_MEDIA_TYPE)===-1?$P:E.PARSER_MEDIA_TYPE,Fe=Wa==="application/xhtml+xml"?r0:nl,Se=wo(E,"ALLOWED_TAGS",Wl,{transform:Fe}),_e=wo(E,"ALLOWED_ATTR",so,{transform:Fe}),sm=wo(E,"ALLOWED_NAMESPACES",HP,{transform:r0}),om=wo(E,"ADD_URI_SAFE_ATTR",$x,{transform:Fe,base:$x}),Vx=wo(E,"ADD_DATA_URI_TAGS",jx,{transform:Fe,base:jx}),on=wo(E,"FORBID_CONTENTS",nm,{transform:Fe}),Ki=wo(E,"FORBID_TAGS",Ht({}),{transform:Fe}),me=wo(E,"FORBID_ATTR",Ht({}),{transform:Fe}),rs=dt(E,"USE_PROFILES")?E.USE_PROFILES&&typeof E.USE_PROFILES=="object"?Ht(E.USE_PROFILES):E.USE_PROFILES:!1,ke=E.ALLOW_ARIA_ATTR!==!1,Be=E.ALLOW_DATA_ATTR!==!1,er=E.ALLOW_UNKNOWN_PROTOCOLS||!1,Nt=E.ALLOW_SELF_CLOSE_IN_ATTR!==!1,ye=E.SAFE_FOR_TEMPLATES||!1,ze=E.SAFE_FOR_XML!==!1,tr=E.WHOLE_DOCUMENT||!1,St=E.RETURN_DOM||!1,ao=E.RETURN_DOM_FRAGMENT||!1,es=E.RETURN_TRUSTED_TYPE||!1,It=E.FORCE_BODY||!1,ts=E.SANITIZE_DOM!==!1,Ux=E.SANITIZE_NAMED_PROPS||!1,tm=E.KEEP_CONTENT!==!1,rm=E.IN_PLACE||!1,$a=cU(E.ALLOWED_URI_REGEXP)?E.ALLOWED_URI_REGEXP:VT,ns=typeof E.NAMESPACE=="string"?E.NAMESPACE:sn,am=dt(E,"MATHML_TEXT_INTEGRATION_POINTS")&&E.MATHML_TEXT_INTEGRATION_POINTS&&typeof E.MATHML_TEXT_INTEGRATION_POINTS=="object"?Ht(E.MATHML_TEXT_INTEGRATION_POINTS):ne({},Wx),cm=dt(E,"HTML_INTEGRATION_POINTS")&&E.HTML_INTEGRATION_POINTS&&typeof E.HTML_INTEGRATION_POINTS=="object"?Ht(E.HTML_INTEGRATION_POINTS):ne({},Yx);let T=dt(E,"CUSTOM_ELEMENT_HANDLING")&&E.CUSTOM_ELEMENT_HANDLING&&typeof E.CUSTOM_ELEMENT_HANDLING=="object"?Ht(E.CUSTOM_ELEMENT_HANDLING):da(null);if(ve=da(null),dt(T,"tagNameCheck")&&qx(T.tagNameCheck)&&(ve.tagNameCheck=T.tagNameCheck),dt(T,"attributeNameCheck")&&qx(T.attributeNameCheck)&&(ve.attributeNameCheck=T.attributeNameCheck),dt(T,"allowCustomizedBuiltInElements")&&typeof T.allowCustomizedBuiltInElements=="boolean"&&(ve.allowCustomizedBuiltInElements=T.allowCustomizedBuiltInElements),Et(ve),ye&&(Be=!1),ao&&(St=!0),rs&&(Se=ne({},GT),_e=da(null),rs.html===!0&&(ne(Se,OT),ne(_e,UT)),rs.svg===!0&&(ne(Se,n0),ne(_e,s0),ne(_e,Ad)),rs.svgFilters===!0&&(ne(Se,o0),ne(_e,s0),ne(_e,Ad)),rs.mathMl===!0&&(ne(Se,i0),ne(_e,HT),ne(_e,Ad))),ae.tagCheck=null,ae.attributeCheck=null,dt(E,"ADD_TAGS")&&(typeof E.ADD_TAGS=="function"?ae.tagCheck=E.ADD_TAGS:Io(E.ADD_TAGS)&&(Se===Wl&&(Se=Ht(Se)),ne(Se,E.ADD_TAGS,Fe))),dt(E,"ADD_ATTR")&&(typeof E.ADD_ATTR=="function"?ae.attributeCheck=E.ADD_ATTR:Io(E.ADD_ATTR)&&(_e===so&&(_e=Ht(_e)),ne(_e,E.ADD_ATTR,Fe))),dt(E,"ADD_URI_SAFE_ATTR")&&Io(E.ADD_URI_SAFE_ATTR)&&ne(om,E.ADD_URI_SAFE_ATTR,Fe),dt(E,"FORBID_CONTENTS")&&Io(E.FORBID_CONTENTS)&&(on===nm&&(on=Ht(on)),ne(on,E.FORBID_CONTENTS,Fe)),dt(E,"ADD_FORBID_CONTENTS")&&Io(E.ADD_FORBID_CONTENTS)&&(on===nm&&(on=Ht(on)),ne(on,E.ADD_FORBID_CONTENTS,Fe)),tm&&(Se["#text"]=!0),tr&&ne(Se,["html","head","body"]),Se.table&&(ne(Se,["tbody"]),delete Ki.tbody),E.TRUSTED_TYPES_POLICY){if(typeof E.TRUSTED_TYPES_POLICY.createHTML!="function")throw Si('TRUSTED_TYPES_POLICY configuration option must provide a "createHTML" hook.');if(typeof E.TRUSTED_TYPES_POLICY.createScriptURL!="function")throw Si('TRUSTED_TYPES_POLICY configuration option must provide a "createScriptURL" hook.');let N=S;S=E.TRUSTED_TYPES_POLICY;try{B=C("")}catch(V){throw S=N,V}}else E.TRUSTED_TYPES_POLICY===null?(S=void 0,B=""):(S===void 0&&(S=k()),S&&typeof B=="string"&&(B=C("")));Ct&&Ct(E),os=E},zx=ne({},[...n0,...o0,...lU]),Jx=ne({},[...i0,...uU]),YP=function(E,T,N){return T.namespaceURI===sn?E==="svg":T.namespaceURI===Yl?E==="svg"&&(N==="annotation-xml"||am[N]):!!zx[E]},qP=function(E,T,N){return T.namespaceURI===sn?E==="math":T.namespaceURI===ql?E==="math"&&cm[N]:!!Jx[E]},zP=function(E,T,N){return T.namespaceURI===ql&&!cm[N]||T.namespaceURI===Yl&&!am[N]?!1:!Jx[E]&&(VP[E]||!zx[E])},JP=function(E){let T=w(E);(!T||!T.tagName)&&(T={namespaceURI:ns,tagName:"template"});let N=nl(E.tagName),V=nl(T.tagName);return sm[E.namespaceURI]?E.namespaceURI===ql?YP(N,T,V):E.namespaceURI===Yl?qP(N,T,V):E.namespaceURI===sn?zP(N,T,V):!!(Wa==="application/xhtml+xml"&&sm[E.namespaceURI]):!1},co=function(E){fa(t.removed,{element:E});try{w(E).removeChild(E)}catch{if(g(E),!w(E))throw Si("a node selected for removal could not be detached from its tree and cannot be safely returned; refusing to sanitize in place")}},zl=function(E){um(E);let T=x(E);if(T){let V=[];ua(T,q=>{fa(V,q)}),ua(V,q=>{try{g(q)}catch{}})}let N=v(E);if(N)for(let V=N.length-1;V>=0;--V){let q=N[V],K=q&&q.name;if(typeof K=="string")try{E.removeAttribute(K)}catch{}}},Yo=function(E,T){try{fa(t.removed,{attribute:T.getAttributeNode(E),from:T})}catch{fa(t.removed,{attribute:null,from:T})}if(T.removeAttribute(E),E==="is")if(St||ao)try{co(T)}catch{}else try{T.setAttribute(E,"")}catch{}},KP=function(E){let T=v(E);if(T)for(let N=T.length-1;N>=0;--N){let V=T[N],q=V&&V.name;if(!(typeof q!="string"||_e[Fe(q)]))try{E.removeAttribute(q)}catch{}}},um=function(E){let T=[E];for(;T.length>0;){let N=T.pop();(b?b(N):N.nodeType)===cr.element&&KP(N);let q=x(N);if(q)for(let K=q.length-1;K>=0;--K)T.push(q[K])}},XP=function(E){if(!ze)return;let T=[E];for(;T.length>0;){let N=T.pop(),V=b?b(N):N.nodeType;if(V===cr.processingInstruction||V===cr.comment&&ft($T,N.data)){try{g(N)}catch{}continue}if(V===cr.element){let K=N,Ue=Fe(I?I(N):N.nodeName);try{K.hasAttribute&&K.hasAttribute("patchsrc")&&K.removeAttribute("patchsrc"),K.hasAttribute&&K.hasAttribute("for")&&Ue!=="label"&&Ue!=="output"&&K.removeAttribute("for")}catch{}}let q=x(N);if(q)for(let K=q.length-1;K>=0;--K)T.push(q[K])}},Kx=function(E){let T=null,N=null;if(It)E="<remove></remove>"+E;else{let K=NT(E,/^[\r\n\t ]+/);N=K&&K[0]}Wa==="application/xhtml+xml"&&ns===sn&&(E='<html xmlns="http://www.w3.org/1999/xhtml"><head></head><body>'+E+"</body></html>");let V=S?C(E):E;if(ns===sn)try{T=new u().parseFromString(V,Wa)}catch{}if(!T||!T.documentElement){T=j.createDocument(ns,"template",null);try{T.documentElement.innerHTML=im?B:V}catch{}}let q=T.body||T.documentElement;return E&&N&&q.insertBefore(r.createTextNode(N),q.childNodes[0]||null),ns===sn?kr.call(T,tr?"html":"body")[0]:tr?T.documentElement:q},Xx=function(E){return oe.call(E.ownerDocument||E,E,c.SHOW_ELEMENT|c.SHOW_COMMENT|c.SHOW_TEXT|c.SHOW_PROCESSING_INSTRUCTION|c.SHOW_CDATA_SECTION,null)},Jl=function(E){return E=tl(E,Dr," "),E=tl(E,mr," "),E=tl(E,nn," "),E},fm=function(E){var T;E.normalize();let N=oe.call(E.ownerDocument||E,E,c.SHOW_TEXT|c.SHOW_COMMENT|c.SHOW_CDATA_SECTION|c.SHOW_PROCESSING_INSTRUCTION,null),V=N.nextNode();for(;V;)V.data=Jl(V.data),V=N.nextNode();let q=(T=E.querySelectorAll)===null||T===void 0?void 0:T.call(E,"template");q&&ua(q,K=>{is(K.content)&&fm(K.content)})},Kl=function(E){let T=I?I(E):null;return typeof T!="string"||Fe(T)!=="form"?!1:typeof E.nodeName!="string"||typeof E.textContent!="string"||typeof E.removeChild!="function"||E.attributes!==v(E)||typeof E.removeAttribute!="function"||typeof E.setAttribute!="function"||typeof E.namespaceURI!="string"||typeof E.insertBefore!="function"||typeof E.hasChildNodes!="function"||E.nodeType!==b(E)||E.childNodes!==x(E)},is=function(E){if(!b||typeof E!="object"||E===null)return!1;try{return b(E)===cr.documentFragment}catch{return!1}},Ya=function(E){if(!b||typeof E!="object"||E===null)return!1;try{return typeof b(E)=="number"}catch{return!1}};function an(F,E,T){F.length!==0&&ua(F,N=>{N.call(t,E,T,os)})}let ZP=function(E,T){return!!(ze&&E.hasChildNodes()&&!Ya(E.firstElementChild)&&ft(jT,E.textContent)&&ft(jT,E.innerHTML)||ze&&E.namespaceURI===sn&&T==="style"&&Ya(E.firstElementChild)||E.nodeType===cr.processingInstruction||ze&&E.nodeType===cr.comment&&ft($T,E.data))},eO=function(E,T){if(!Ki[T]&&tC(T)&&(ve.tagNameCheck instanceof RegExp&&ft(ve.tagNameCheck,T)||ve.tagNameCheck instanceof Function&&ve.tagNameCheck(T)))return!1;if(tm&&!on[T]){let N=w(E),V=x(E);if(V&&N){let q=V.length;for(let K=q-1;K>=0;--K){let Ue=rm?V[K]:f(V[K],!0);N.insertBefore(Ue,h(E))}}}return co(E),!0},Zx=function(E,T){if(an(Ae.beforeSanitizeElements,E,null),E!==T&&w(E)===null)return!0;if(Kl(E))return co(E),!0;let N=Fe(I?I(E):E.nodeName);if(an(Ae.uponSanitizeElement,E,{tagName:N,allowedTags:Se}),E!==T&&w(E)===null)return!0;if(ZP(E,N))return co(E),!0;if(Ki[N]||!(ae.tagCheck instanceof Function&&ae.tagCheck(N))&&!Se[N]){let q=eO(E,N);return q===!1&&an(Ae.afterSanitizeElements,E,null),q}if((b?b(E):E.nodeType)===cr.element&&!JP(E)||(N==="noscript"||N==="noembed"||N==="noframes")&&ft(CU,E.innerHTML))return co(E),!0;if(ye&&E.nodeType===cr.text){let q=Jl(E.textContent);E.textContent!==q&&(fa(t.removed,{element:E.cloneNode()}),E.textContent=q)}return an(Ae.afterSanitizeElements,E,null),!1},eC=function(E,T,N){if(me[T]||ze&&T==="patchsrc"||ze&&T==="for"&&E!=="label"&&E!=="output"||ts&&(T==="id"||T==="name")&&(N in r||N in WP))return!1;let V=_e[T]||ae.attributeCheck instanceof Function&&ae.attributeCheck(T,E);if(!(Be&&ft(Dn,T))){if(!(ke&&ft(Ji,T))){if(V){if(!om[T]){if(!ft($a,tl(N,io,""))){if(!((T==="src"||T==="xlink:href"||T==="href")&&E!=="script"&&LT(N,"data:")===0&&Vx[E])){if(!(er&&!ft(Nn,tl(N,io,"")))){if(N)return!1}}}}}else if(!(tC(E)&&(ve.tagNameCheck instanceof RegExp&&ft(ve.tagNameCheck,E)||ve.tagNameCheck instanceof Function&&ve.tagNameCheck(E))&&(ve.attributeNameCheck instanceof RegExp&&ft(ve.attributeNameCheck,T)||ve.attributeNameCheck instanceof Function&&ve.attributeNameCheck(T,E))||T==="is"&&ve.allowCustomizedBuiltInElements&&(ve.tagNameCheck instanceof RegExp&&ft(ve.tagNameCheck,N)||ve.tagNameCheck instanceof Function&&ve.tagNameCheck(N))))return!1}}return!0},tO=ne({},["annotation-xml","color-profile","font-face","font-face-format","font-face-name","font-face-src","font-face-uri","missing-glyph"]),tC=function(E){return!tO[nl(E)]&&ft(em,E)},rO=function(E,T,N,V){if(S&&typeof d=="object"&&typeof d.getAttributeType=="function"&&!N)switch(d.getAttributeType(E,T)){case"TrustedHTML":return C(V);case"TrustedScriptURL":return M(V)}return V},nO=function(E,T,N,V){try{N?E.setAttributeNS(N,T,V):E.setAttribute(T,V),Kl(E)?co(E):DT(t.removed)}catch{Yo(T,E)}},rC=function(E){an(Ae.beforeSanitizeAttributes,E,null);let T=E.attributes;if(!T||Kl(E))return;let N={attrName:"",attrValue:"",keepAttr:!0,allowedAttributes:_e,forceKeepAttr:void 0},V=T.length,q=Fe(E.nodeName);for(;V--;){let K=T[V],Ue=K.name,vt=K.namespaceURI,Nr=K.value,qt=Fe(Ue),Lr=Nr,Lt=Ue==="value"?Lr:rU(Lr);if(N.attrName=qt,N.attrValue=Lt,N.keepAttr=!0,N.forceKeepAttr=void 0,an(Ae.uponSanitizeAttribute,E,N),Lt=N.attrValue,Ux&&(qt==="id"||qt==="name")&&LT(Lt,Hx)!==0&&(Yo(Ue,E),Lt=Hx+Lt),ze&&ft(/((--!?|])>)|<\/(style|script|title|xmp|textarea|noscript|iframe|noembed|noframes)/i,Lt)){Yo(Ue,E);continue}if(qt==="attributename"&&NT(Lt,"href")){Yo(Ue,E);continue}if(!N.forceKeepAttr){if(!N.keepAttr){Yo(Ue,E);continue}if(!Nt&&ft(EU,Lt)){Yo(Ue,E);continue}if(ye&&(Lt=Jl(Lt)),!eC(q,qt,Lt)){Yo(Ue,E);continue}Lt=rO(q,qt,vt,Lt),Lt!==Lr&&nO(E,Ue,vt,Lt)}}an(Ae.afterSanitizeAttributes,E,null)},Xl=function(E){let T=null,N=Xx(E);for(an(Ae.beforeSanitizeShadowDOM,E,null);T=N.nextNode();)if(an(Ae.uponSanitizeShadowNode,T,null),Zx(T,E),rC(T),is(T.content)&&Xl(T.content),(b?b(T):T.nodeType)===cr.element){let q=y(T);is(q)&&(dm(q),Xl(q))}an(Ae.afterSanitizeShadowDOM,E,null)},dm=function(E){let T=[{node:E,shadow:null}];for(;T.length>0;){let N=T.pop();if(N.shadow){Xl(N.shadow);continue}let V=N.node,K=(b?b(V):V.nodeType)===cr.element,Ue=x(V);if(Ue)for(let vt=Ue.length-1;vt>=0;--vt)T.push({node:Ue[vt],shadow:null});if(K){let vt=I?I(V):null;if(typeof vt=="string"&&Fe(vt)==="template"){let Nr=V.content;is(Nr)&&T.push({node:Nr,shadow:null})}}if(K){let vt=y(V);is(vt)&&T.push({node:null,shadow:vt},{node:vt,shadow:null})}}};return t.sanitize=function(F){let E=arguments.length>1&&arguments[1]!==void 0?arguments[1]:{},T=null,N=null,V=null,q=null;if(im=!F,im&&(F="<!-->"),typeof F!="string"&&!Ya(F)&&(F=aU(F),typeof F!="string"))throw Si("dirty is not a string, aborting");if(!t.isSupported)return F;Ln?(Se=Xi,_e=Zi):lm(E),(Ae.uponSanitizeElement.length>0||Ae.uponSanitizeAttribute.length>0)&&(Se=Ht(Se)),Ae.uponSanitizeAttribute.length>0&&(_e=Ht(_e)),t.removed=[];let K=rm&&typeof F!="string"&&Ya(F);if(K){XP(F);let qt=I?I(F):F.nodeName;if(typeof qt=="string"){let Lr=Fe(qt);if(!Se[Lr]||Ki[Lr])throw zl(F),Si("root node is forbidden and cannot be sanitized in-place")}if(Kl(F))throw zl(F),Si("root node is clobbered and cannot be sanitized in-place");try{dm(F)}catch(Lr){throw zl(F),Lr}}else if(Ya(F))T=Kx("<!---->"),N=T.ownerDocument.importNode(F,!0),N.nodeType===cr.element&&N.nodeName==="BODY"||N.nodeName==="HTML"?T=N:T.appendChild(N),dm(N);else{if(!St&&!ye&&!tr&&F.indexOf("<")===-1)return S&&es?C(F):F;if(T=Kx(F),!T)return St?null:es?B:""}T&&It&&co(T.firstChild);let Ue=K?F:T,vt=Xx(Ue);try{for(;V=vt.nextNode();)Zx(V,Ue),rC(V),is(V.content)&&Xl(V.content)}catch(qt){throw K&&(zl(F),ua(t.removed,Lr=>{Lr.element&&um(Lr.element)})),qt}if(K)return ua(t.removed,qt=>{qt.element&&um(qt.element)}),ye&&fm(F),F;if(St){if(ye&&fm(T),ao)for(q=te.call(T.ownerDocument);T.firstChild;)q.appendChild(T.firstChild);else q=T;return(_e.shadowroot||_e.shadowrootmode)&&(q=ot.call(n,q,!0)),q}let Nr=tr?T.outerHTML:T.innerHTML;return tr&&Se["!doctype"]&&T.ownerDocument&&T.ownerDocument.doctype&&T.ownerDocument.doctype.name&&ft(yU,T.ownerDocument.doctype.name)&&(Nr="<!DOCTYPE "+T.ownerDocument.doctype.name+`>
+`+Nr),ye&&(Nr=Jl(Nr)),S&&es?C(Nr):Nr},t.setConfig=function(){let F=arguments.length>0&&arguments[0]!==void 0?arguments[0]:{};lm(F),Ln=!0,Xi=Se,Zi=_e},t.clearConfig=function(){os=null,Ln=!1,Xi=null,Zi=null,S=R,B=""},t.isValidAttribute=function(F,E,T){os||lm({});let N=Fe(F),V=Fe(E);return eC(N,V,T)},t.addHook=function(F,E){typeof E=="function"&&dt(Ae,F)&&fa(Ae[F],E)},t.removeHook=function(F,E){if(dt(Ae,F)){if(E!==void 0){let T=eU(Ae[F],E);return T===-1?void 0:tU(Ae[F],T,1)[0]}return DT(Ae[F])}},t.removeHooks=function(F){dt(Ae,F)&&(Ae[F]=[])},t.removeAllHooks=function(){Ae=WT()},t}var YT,kT,K6,X6,Z6,Ct,Et,da,qT,a0,c0,ua,eU,DT,fa,tU,Io,nl,r0,NT,tl,LT,rU,nU,oU,FT,PT,dt,rl,ft,Si,OT,n0,o0,lU,i0,uU,GT,UT,s0,HT,Ad,fU,dU,AU,mU,pU,VT,gU,hU,yU,xU,jT,$T,CU,EU,cr,bU,wU,WT,wo,JT,KT=m(()=>{YT=Object.entries,kT=Object.setPrototypeOf,K6=Object.isFrozen,X6=Object.getPrototypeOf,Z6=Object.getOwnPropertyDescriptor,Ct=Object.freeze,Et=Object.seal,da=Object.create,qT=typeof Reflect<"u"&&Reflect,a0=qT.apply,c0=qT.construct;Ct||(Ct=function(t){return t});Et||(Et=function(t){return t});a0||(a0=function(t,r){for(var n=arguments.length,o=new Array(n>2?n-2:0),i=2;i<n;i++)o[i-2]=arguments[i];return t.apply(r,o)});c0||(c0=function(t){for(var r=arguments.length,n=new Array(r>1?r-1:0),o=1;o<r;o++)n[o-1]=arguments[o];return new t(...n)});ua=et(Array.prototype.forEach),eU=et(Array.prototype.lastIndexOf),DT=et(Array.prototype.pop),fa=et(Array.prototype.push),tU=et(Array.prototype.splice),Io=Array.isArray,nl=et(String.prototype.toLowerCase),r0=et(String.prototype.toString),NT=et(String.prototype.match),tl=et(String.prototype.replace),LT=et(String.prototype.indexOf),rU=et(String.prototype.trim),nU=et(Number.prototype.toString),oU=et(Boolean.prototype.toString),FT=typeof BigInt>"u"?null:et(BigInt.prototype.toString),PT=typeof Symbol>"u"?null:et(Symbol.prototype.toString),dt=et(Object.prototype.hasOwnProperty),rl=et(Object.prototype.toString),ft=et(RegExp.prototype.test),Si=iU(TypeError);OT=Ct(["a","abbr","acronym","address","area","article","aside","audio","b","bdi","bdo","big","blink","blockquote","body","br","button","canvas","caption","center","cite","code","col","colgroup","content","data","datalist","dd","decorator","del","details","dfn","dialog","dir","div","dl","dt","element","em","fieldset","figcaption","figure","font","footer","form","h1","h2","h3","h4","h5","h6","head","header","hgroup","hr","html","i","img","input","ins","kbd","label","legend","li","main","map","mark","marquee","menu","menuitem","meter","nav","nobr","ol","optgroup","option","output","p","picture","pre","progress","q","rp","rt","ruby","s","samp","search","section","select","shadow","slot","small","source","spacer","span","strike","strong","style","sub","summary","sup","table","tbody","td","template","textarea","tfoot","th","thead","time","tr","track","tt","u","ul","var","video","wbr"]),n0=Ct(["svg","a","altglyph","altglyphdef","altglyphitem","animatecolor","animatemotion","animatetransform","circle","clippath","defs","desc","ellipse","enterkeyhint","exportparts","filter","font","g","glyph","glyphref","hkern","image","inputmode","line","lineargradient","marker","mask","metadata","mpath","part","path","pattern","polygon","polyline","radialgradient","rect","stop","style","switch","symbol","text","textpath","title","tref","tspan","view","vkern"]),o0=Ct(["feBlend","feColorMatrix","feComponentTransfer","feComposite","feConvolveMatrix","feDiffuseLighting","feDisplacementMap","feDistantLight","feDropShadow","feFlood","feFuncA","feFuncB","feFuncG","feFuncR","feGaussianBlur","feImage","feMerge","feMergeNode","feMorphology","feOffset","fePointLight","feSpecularLighting","feSpotLight","feTile","feTurbulence"]),lU=Ct(["animate","color-profile","cursor","discard","font-face","font-face-format","font-face-name","font-face-src","font-face-uri","foreignobject","hatch","hatchpath","mesh","meshgradient","meshpatch","meshrow","missing-glyph","script","set","solidcolor","unknown","use"]),i0=Ct(["math","menclose","merror","mfenced","mfrac","mglyph","mi","mlabeledtr","mmultiscripts","mn","mo","mover","mpadded","mphantom","mroot","mrow","ms","mspace","msqrt","mstyle","msub","msup","msubsup","mtable","mtd","mtext","mtr","munder","munderover","mprescripts"]),uU=Ct(["maction","maligngroup","malignmark","mlongdiv","mscarries","mscarry","msgroup","mstack","msline","msrow","semantics","annotation","annotation-xml","mprescripts","none"]),GT=Ct(["#text"]),UT=Ct(["accept","action","align","alt","autocapitalize","autocomplete","autopictureinpicture","autoplay","background","bgcolor","border","capture","cellpadding","cellspacing","checked","cite","class","clear","color","cols","colspan","command","commandfor","controls","controlslist","coords","crossorigin","datetime","decoding","default","dir","disabled","disablepictureinpicture","disableremoteplayback","download","draggable","enctype","enterkeyhint","exportparts","face","for","headers","height","hidden","high","href","hreflang","id","inert","inputmode","integrity","ismap","kind","label","lang","list","loading","loop","low","max","maxlength","media","method","min","minlength","multiple","muted","name","nonce","noshade","novalidate","nowrap","open","optimum","part","pattern","placeholder","playsinline","popover","popovertarget","popovertargetaction","poster","preload","pubdate","radiogroup","readonly","rel","required","rev","reversed","role","rows","rowspan","spellcheck","scope","selected","shape","size","sizes","slot","span","srclang","start","src","srcset","step","style","summary","tabindex","title","translate","type","usemap","valign","value","width","wrap","xmlns"]),s0=Ct(["accent-height","accumulate","additive","alignment-baseline","amplitude","ascent","attributename","attributetype","azimuth","basefrequency","baseline-shift","begin","bias","by","class","clip","clippathunits","clip-path","clip-rule","color","color-interpolation","color-interpolation-filters","color-profile","color-rendering","cx","cy","d","dx","dy","diffuseconstant","direction","display","divisor","dominant-baseline","dur","edgemode","elevation","end","exponent","fill","fill-opacity","fill-rule","filter","filterunits","flood-color","flood-opacity","font-family","font-size","font-size-adjust","font-stretch","font-style","font-variant","font-weight","fx","fy","g1","g2","glyph-name","glyphref","gradientunits","gradienttransform","height","href","id","image-rendering","in","in2","intercept","k","k1","k2","k3","k4","kerning","keypoints","keysplines","keytimes","lang","lengthadjust","letter-spacing","kernelmatrix","kernelunitlength","lighting-color","local","marker-end","marker-mid","marker-start","markerheight","markerunits","markerwidth","maskcontentunits","maskunits","max","mask","mask-type","media","method","mode","min","name","numoctaves","offset","operator","opacity","order","orient","orientation","origin","overflow","paint-order","path","pathlength","patterncontentunits","patterntransform","patternunits","points","preservealpha","preserveaspectratio","primitiveunits","r","rx","ry","radius","refx","refy","repeatcount","repeatdur","restart","result","rotate","scale","seed","shape-rendering","slope","specularconstant","specularexponent","spreadmethod","startoffset","stddeviation","stitchtiles","stop-color","stop-opacity","stroke-dasharray","stroke-dashoffset","stroke-linecap","stroke-linejoin","stroke-miterlimit","stroke-opacity","stroke","stroke-width","style","surfacescale","systemlanguage","tabindex","tablevalues","targetx","targety","transform","transform-origin","text-anchor","text-decoration","text-orientation","text-rendering","textlength","type","u1","u2","unicode","values","viewbox","visibility","version","vert-adv-y","vert-origin-x","vert-origin-y","width","word-spacing","wrap","writing-mode","xchannelselector","ychannelselector","x","x1","x2","xmlns","y","y1","y2","z","zoomandpan"]),HT=Ct(["accent","accentunder","align","bevelled","close","columnalign","columnlines","columnspacing","columnspan","denomalign","depth","dir","display","displaystyle","encoding","fence","frame","height","href","id","largeop","length","linethickness","lquote","lspace","mathbackground","mathcolor","mathsize","mathvariant","maxsize","minsize","movablelimits","notation","numalign","open","rowalign","rowlines","rowspacing","rowspan","rspace","rquote","scriptlevel","scriptminsize","scriptsizemultiplier","selection","separator","separators","stretchy","subscriptshift","supscriptshift","symmetric","voffset","width","xmlns"]),Ad=Ct(["xlink:href","xml:id","xlink:title","xml:space","xmlns:xlink"]),fU=Et(/{{[\w\W]*|^[\w\W]*}}/g),dU=Et(/<%[\w\W]*|^[\w\W]*%>/g),AU=Et(/\${[\w\W]*/g),mU=Et(/^data-[\-\w.\u00B7-\uFFFF]+$/),pU=Et(/^aria-[\-\w]+$/),VT=Et(/^(?:(?:(?:f|ht)tps?|mailto|tel|callto|sms|cid|xmpp|matrix):|[^a-z]|[a-z+.\-]+(?:[^a-z+.\-:]|$))/i),gU=Et(/^(?:\w+script|data):/i),hU=Et(/[\u0000-\u0020\u00A0\u1680\u180E\u2000-\u2029\u205F\u3000]/g),yU=Et(/^html$/i),xU=Et(/^[a-z][.\w]*(-[.\w]+)+$/i),jT=Et(/<[/\w!]/g),$T=Et(/<[/\w]/g),CU=Et(/<\/no(script|embed|frames)/i),EU=Et(/\/>/i),cr={element:1,attribute:2,text:3,cdataSection:4,entityReference:5,entityNode:6,processingInstruction:7,comment:8,document:9,documentType:10,documentFragment:11,notation:12},bU=function(){return typeof window>"u"?null:window},wU=function(t,r){if(typeof t!="object"||typeof t.createPolicy!="function")return null;let n=null,o="data-tt-policy-suffix";r&&r.hasAttribute(o)&&(n=r.getAttribute(o));let i="dompurify"+(n?"#"+n:"");try{return t.createPolicy(i,{createHTML(s){return s},createScriptURL(s){return s}})}catch{return console.warn("TrustedTypes policy "+i+" could not be created."),null}},WT=function(){return{afterSanitizeAttributes:[],afterSanitizeElements:[],afterSanitizeShadowDOM:[],beforeSanitizeAttributes:[],beforeSanitizeElements:[],beforeSanitizeShadowDOM:[],uponSanitizeAttribute:[],uponSanitizeElement:[],uponSanitizeShadowNode:[]}},wo=function(t,r,n,o){return dt(t,r)&&Io(t[r])?ne(o.base?Ht(o.base):{},t[r],o.transform):n};JT=zT()});var eM={};Bt(eM,{default:()=>ZT});function ZT({value:e,className:t}){let r=(0,md.useRef)(null);return(0,md.useLayoutEffect)(()=>{let n=r.current;if(n)for(let o of n.querySelectorAll("a"))o.setAttribute("rel","noopener noreferrer"),o.setAttribute("target","_blank")},[e]),(0,XT.jsx)("span",{ref:r,className:t,dangerouslySetInnerHTML:{__html:JT.sanitize(e)}})}var XT,md,tM=m(()=>{XT=p(O(),1),md=p(Q(),1);KT()});function BU(e){return vU.test(e)}function TU(e){return e.includes("<")||e.includes("://")}function MU({value:e,className:t}){let r=(0,So.useRef)(null);return(0,So.useLayoutEffect)(()=>{let n=r.current;if(n)try{n.setHTML(e);for(let o of n.querySelectorAll("a"))o.setAttribute("rel","noopener noreferrer"),o.setAttribute("target","_blank")}catch(o){console.error(o)}},[e]),(0,vi.jsx)("span",{ref:r,className:t})}function vo({html:e,className:t}){let r=`${e}`;if(!TU(r))return(0,vi.jsx)("span",{className:t,children:r});let n=RT(r),o=BU(n)?n:(0,rM.default)(n);return typeof Element<"u"&&Element.prototype.setHTML?(0,vi.jsx)(MU,{value:o,className:t}):(0,vi.jsx)(So.Suspense,{fallback:(0,vi.jsx)("span",{className:t}),children:(0,vi.jsx)(SU,{value:o,className:t})})}var vi,So,rM,IU,SU,vU,l0=m(()=>{vi=p(O(),1),So=p(Q(),1),rM=p(n1(),1);bo();IU=["a","b","br","code","div","em","h1","h2","h3","h4","h5","h6","i","img","li","mark","p","pre","span","small","strong","table","tbody","sup","sub","td","tfoot","th","thead","tr","u","ul"],SU=(0,So.lazy)(()=>Promise.resolve().then(()=>(tM(),eM))),vU=new RegExp(IU.map(e=>String.raw`<${e}\b[^>]*>`).join("|"),"i")});function RU({error:e}){let{classes:t}=iM();return(0,lr.jsx)("div",{className:t.errorBox,children:(0,lr.jsx)(e1,{error:e})})}var lr,nM,Mt,oM,iM,QU,sM,aM=m(()=>{lr=p(O(),1),nM=p(Q(),1);Qg();Mt=p(U(),1),oM=p(Y(),1);Eg();t1();l0();He();iM=Z()(e=>({closeButton:{position:"absolute",right:e.spacing(1),top:e.spacing(1),color:e.palette.grey[500]},errorBox:{width:800,margin:40}}));QU=(0,oM.observer)(function(t){let{classes:r}=iM(),{titleNode:n,...o}=t,{title:i,header:s,children:a,onClose:c}=o,l=(0,Mt.useTheme)();return(0,lr.jsx)(Mt.Dialog,{...o,children:(0,lr.jsxs)(Mt.ScopedCssBaseline,{children:[(0,nM.isValidElement)(s)?s:(0,lr.jsxs)(Mt.DialogTitle,{children:[n||(0,lr.jsx)(vo,{html:i||""}),c?(0,lr.jsx)(Mt.IconButton,{className:r.closeButton,onClick:u=>{c(u,"backdropClick")},children:(0,lr.jsx)(Qf,{})}):null]}),(0,lr.jsx)(Mt.Divider,{}),(0,lr.jsx)(Hs,{FallbackComponent:RU,children:(0,lr.jsx)(Mt.ThemeProvider,{theme:(0,Mt.createTheme)(l,{components:{MuiInputBase:{styleOverrides:{input:{boxSizing:"content-box!important"}}}}}),children:a})})]})})}),sM=QU});function u0({onClose:e,helpText:t,label:r}){return(0,Bi.jsx)(sM,{open:!0,onClose:e,title:"Help",titleNode:r?(0,Bi.jsxs)(Bi.Fragment,{children:["Help: ",r]}):void 0,onClick:n=>{n.stopPropagation()},onMouseDown:n=>{n.stopPropagation()},children:(0,Bi.jsx)(cM.DialogContent,{children:t})})}var Bi,cM,lM=m(()=>{Bi=p(O(),1),cM=p(U(),1);aM()});function f0({helpText:e,label:t}){let[r,n]=(0,pd.useState)(!1);return(0,Jn.jsxs)(Jn.Fragment,{children:[(0,Jn.jsx)(uM.IconButton,{size:"small",onClick:o=>{o.stopPropagation(),n(!0)},style:{marginLeft:4,padding:4},children:(0,Jn.jsx)(zS,{fontSize:"small"})}),r?(0,Jn.jsxs)(pd.Suspense,{fallback:null,children:[(0,Jn.jsx)(u0,{helpText:e,label:t,onClose:o=>{o.stopPropagation(),n(!1)}})," "]}):null]})}var Jn,pd,uM,fM=m(()=>{Jn=p(O(),1),pd=p(Q(),1);JS();uM=p(U(),1);lM()});var dM,AM,mM,_U,pM,gM=m(()=>{dM=p(O(),1),AM=p(Q(),1),mM=p(U(),1),_U=AM.forwardRef(function(t,r){return(0,dM.jsx)(mM.Menu,{...t,ref:r,style:{pointerEvents:"none",...t.style},slotProps:{...t.slotProps,paper:{style:{pointerEvents:"auto"}}}})}),pM=_U});var hM,yM,xM=m(()=>{"use client";or();hM=p(O(),1),yM=(0,Te.createSvgIcon)((0,hM.jsx)("path",{d:"m10 17 5-5-5-5z"}),"ArrowRight")});var CM,EM,bM=m(()=>{"use client";or();CM=p(O(),1),EM=(0,Te.createSvgIcon)((0,CM.jsx)("path",{d:"M19 3H5c-1.11 0-2 .9-2 2v14c0 1.1.89 2 2 2h14c1.11 0 2-.9 2-2V5c0-1.1-.89-2-2-2m-9 14-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8z"}),"CheckBox")});var wM,IM,SM=m(()=>{"use client";or();wM=p(O(),1),IM=(0,Te.createSvgIcon)((0,wM.jsx)("path",{d:"M19 5v14H5V5zm0-2H5c-1.1 0-2 .9-2 2v14c0 1.1.9 2 2 2h14c1.1 0 2-.9 2-2V5c0-1.1-.9-2-2-2"}),"CheckBoxOutlineBlank")});var vM,BM,TM=m(()=>{"use client";or();vM=p(O(),1),BM=(0,Te.createSvgIcon)((0,vM.jsx)("path",{d:"M12 7c-2.76 0-5 2.24-5 5s2.24 5 5 5 5-2.24 5-5-2.24-5-5-5m0-5C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m0 18c-4.42 0-8-3.58-8-8s3.58-8 8-8 8 3.58 8 8-3.58 8-8 8"}),"RadioButtonChecked")});var MM,RM,QM=m(()=>{"use client";or();MM=p(O(),1),RM=(0,Te.createSvgIcon)((0,MM.jsx)("path",{d:"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m0 18c-4.42 0-8-3.58-8-8s3.58-8 8-8 8 3.58 8 8-3.58 8-8 8"}),"RadioButtonUnchecked")});function _M(e){let{classes:t}=kU(),{type:r}=e,n,o;"checked"in e&&({checked:n,disabled:o}=e);let i;switch(r){case"subMenu":{i=(0,Bo.jsx)(yM,{color:"action"});break}case"checkbox":{n?i=(0,Bo.jsx)(EM,{color:o?"inherit":void 0}):i=(0,Bo.jsx)(IM,{color:"action"});break}case"radio":{n?i=(0,Bo.jsx)(BM,{color:o?"inherit":void 0}):i=(0,Bo.jsx)(RM,{color:"action"});break}}return(0,Bo.jsx)("div",{className:t.menuItemEndDecoration,children:i})}var Bo,gd,kU,kM=m(()=>{Bo=p(O(),1);xM();bM();SM();TM();QM();gd=p(U(),1);He();kU=Z()({menuItemEndDecoration:{padding:0,margin:0,height:16}})});function DM(e){if(typeof e=="string")return e.toLowerCase().replace(/\s+/g,"_")}function DU({title:e,Icon:t,inset:r,menuItems:n,onMenuItemClick:o,closeAfterItemClick:i,onCloseRoot:s,isOpen:a,onOpen:c,onClose:l}){let[u,d]=(0,d0.useState)(null),A=DM(e);return(0,Ee.jsxs)(Ee.Fragment,{children:[(0,Ee.jsxs)(Vt.MenuItem,{ref:d,"data-testid":A?`cascading-submenu-${A}`:void 0,onMouseOver:c,onFocus:c,onClick:c,children:[t?(0,Ee.jsx)(Vt.ListItemIcon,{children:(0,Ee.jsx)(t,{})}):null,(0,Ee.jsx)(Vt.ListItemText,{primary:e,inset:r}),(0,Ee.jsx)(WS,{})]}),(0,Ee.jsx)(pM,{open:a,anchorEl:u,onClose:l,anchorOrigin:{vertical:"top",horizontal:"right"},transformOrigin:{vertical:"top",horizontal:"left"},children:(0,Ee.jsx)(NM,{closeAfterItemClick:i,onMenuItemClick:o,menuItems:n,onCloseRoot:s})})]})}function NM({onMenuItemClick:e,closeAfterItemClick:t,menuItems:r,onCloseRoot:n}){let[o,i]=(0,d0.useState)(),s=()=>{i(void 0)},a=r.some(u=>"icon"in u&&u.icon),c=r.some(u=>(u.type==="checkbox"||u.type==="radio")&&"helpText"in u&&u.helpText),l=r.toSorted((u,d)=>(d.priority||0)-(u.priority||0));return(0,Ee.jsx)(Ee.Fragment,{children:l.map((u,d)=>{if("subMenu"in u)return(0,Ee.jsx)(DU,{title:u.label,Icon:u.icon,inset:a&&!u.icon,onMenuItemClick:e,menuItems:u.subMenu,closeAfterItemClick:t,onCloseRoot:n,isOpen:o===d,onOpen:()=>{i(d)},onClose:s},`subMenu-${u.label}-${d}`);if(u.type==="divider")return(0,Ee.jsx)(Vt.Divider,{component:"li"},`divider-${d}`);if(u.type==="subHeader")return(0,Ee.jsx)(Vt.ListSubheader,{children:u.label},`subHeader-${u.label}-${d}`);let A=u,f=A.helpText,g=A.type==="checkbox"||A.type==="radio",h=DM(A.label);return(0,Ee.jsxs)(Vt.MenuItem,{"data-testid":h?`cascading-menuitem-${h}`:void 0,disabled:!!A.disabled,onClick:x=>{t&&n(),e(x,A.onClick)},onMouseOver:s,children:[A.icon?(0,Ee.jsx)(Vt.ListItemIcon,{children:(0,Ee.jsx)(A.icon,{})}):null,(0,Ee.jsx)(Vt.ListItemText,{primary:A.label,secondary:A.subLabel,inset:a&&!A.icon}),(0,Ee.jsx)("div",{style:{flexGrow:1,minWidth:10}}),g?(0,Ee.jsx)(_M,{type:A.type,checked:A.checked,disabled:A.disabled}):null,f?(0,Ee.jsx)(f0,{helpText:f,label:A.label}):g&&c?(0,Ee.jsx)("div",{style:{marginLeft:4,padding:4,width:28,height:28}}):null]},`${A.label}-${d}`)})})}function A0({onMenuItemClick:e,closeAfterItemClick:t=!0,menuItems:r,open:n,onClose:o,anchorEl:i,anchorOrigin:s,transformOrigin:a,anchorReference:c,anchorPosition:l,slotProps:u,marginThreshold:d,style:A}){let f=Array.isArray(r)?r:r();return(0,Ee.jsx)(Vt.Menu,{anchorEl:i,open:n,onClose:o,anchorOrigin:s,transformOrigin:a,anchorReference:c,anchorPosition:l,slotProps:u,marginThreshold:d??void 0,style:A,children:(0,Ee.jsx)(NM,{menuItems:f,closeAfterItemClick:t,onMenuItemClick:e,onCloseRoot:o})})}var Ee,d0,Vt,LM=m(()=>{Ee=p(O(),1),d0=p(Q(),1);YS();Vt=p(U(),1);fM();gM();kM()});function NU({children:e,menuItems:t,closeAfterItemClick:r=!0,stopPropagation:n,disabled:o,setOpen:i,ButtonComponent:s=FM.IconButton,onClick:a,anchorOrigin:c,transformOrigin:l,marginThreshold:u,...d}){let[A,f]=(0,hd.useState)(null),g=!!A;(0,hd.useEffect)(()=>{i?.(g)},[g,i]);let h=o??(Array.isArray(t)&&t.length===0);return(0,Ti.jsxs)(Ti.Fragment,{children:[(0,Ti.jsx)(s,{onClick:x=>{n&&x.stopPropagation(),f(x.currentTarget),a?.(x)},...d,disabled:h,children:e}),g?(0,Ti.jsx)(A0,{open:g,onClose:()=>{f(null)},anchorEl:A,anchorOrigin:c,transformOrigin:l,marginThreshold:u,menuItems:t,closeAfterItemClick:r,onMenuItemClick:(x,w)=>{w()}}):null]})}var Ti,hd,FM,Cn,Aa=m(()=>{Ti=p(O(),1),hd=p(Q(),1),FM=p(U(),1);LM();Cn=NU});var PM,OM,GM=m(()=>{"use client";we();PM=p(O(),1),OM=W((0,PM.jsx)("path",{d:"M12 2C6.49 2 2 6.49 2 12s4.49 10 10 10c1.38 0 2.5-1.12 2.5-2.5 0-.61-.23-1.2-.64-1.67-.08-.1-.13-.21-.13-.33 0-.28.22-.5.5-.5H16c3.31 0 6-2.69 6-6 0-4.96-4.49-9-10-9m5.5 11c-.83 0-1.5-.67-1.5-1.5s.67-1.5 1.5-1.5 1.5.67 1.5 1.5-.67 1.5-1.5 1.5m-3-4c-.83 0-1.5-.67-1.5-1.5S13.67 6 14.5 6s1.5.67 1.5 1.5S15.33 9 14.5 9M5 11.5c0-.83.67-1.5 1.5-1.5s1.5.67 1.5 1.5S7.33 13 6.5 13 5 12.33 5 11.5m6-4c0 .83-.67 1.5-1.5 1.5S8 8.33 8 7.5 8.67 6 9.5 6s1.5.67 1.5 1.5"}),"Palette")});var UM=m(()=>{Ep();wp();Ip();bp()});var HM,LU,ol,m0=m(()=>{UM();Mc();rg();ho();pf([gf]);HM={A:An[500],C:dn[500],G:Gn[500],T:Or[500],U:Or[500]},LU={none:{},nucleotide:HM,clustal:{G:"orange",P:"orange",S:"orange",T:"orange",H:"red",K:"red",R:"red",F:"blue",W:"blue",Y:"blue",I:"green",L:"green",M:"green",V:"green"},lesk:{G:"orange",A:"orange",S:"orange",T:"orange",C:"green",V:"green",I:"green",L:"green",P:"green",F:"green",Y:"green",M:"green",W:"green",N:"magenta",Q:"magenta",H:"magenta",D:"red",E:"red",K:"blue",R:"blue"},maeditor:{A:"lightgreen",G:"lightgreen",C:"green",D:"darkgreen",E:"darkgreen",N:"darkgreen",Q:"darkgreen",I:"blue",L:"blue",M:"blue",V:"blue",F:"#c8a2c8",W:"#c8a2c8",Y:"#c8a2c8",H:"darkblue",K:"orange",R:"orange",P:"pink",S:"red",T:"red"},percent_identity_dynamic:{},flower:{A:"#b18a51",C:"#ff5701",D:"#01a578",E:"#2da0a1",F:"#fa559d",G:"#b1c23c",H:"#0194f9",I:"#f27663",K:"#7fc3d7",L:"#df6e75",M:"#fe9daf",N:"#0bcec6",P:"#4fa32a",Q:"#7295ae",R:"#83bff1",S:"#b4bd9b",T:"#d2b576",V:"#fd997b",W:"#ff2ded",Y:"#c96ecf"},rainbow_dna:{A:"#3737f5",C:"#37f537",G:"#f5f537",T:"#f53737",U:"#f53737"},clustalx_protein:{A:"#197fe5",C:"#e57f7f",D:"#cc4ccc",E:"#cc4ccc",F:"#197fe5",G:"#e5994c",H:"#19b2b2",I:"#197fe5",K:"#e53319",L:"#197fe5",M:"#197fe5",N:"#19cc19",P:"#cccc00",Q:"#19cc19",R:"#e53319",S:"#19cc19",T:"#19cc19",V:"#197fe5",W:"#197fe5",Y:"#19b2b2"},clustalx_protein_dynamic:{},clustalx_dna:{A:"#e53319",C:"#197fe5",G:"#e5994c",T:"#19cc19",U:"#19cc19"},jbrowse_dna:HM,jalview_buried:{A:"#00a35c",R:"#00fc03",N:"#00eb14",D:"#00eb14",C:"#0000ff",Q:"#00f10e",E:"#00f10e",G:"#009d62",H:"#00d52a",I:"#0054ab",L:"#007b84",K:"#00ff00",M:"#009768",F:"#008778",P:"#00e01f",S:"#00d52a",T:"#00db24",W:"#00a857",Y:"#00e619",V:"#005fa0",B:"#00eb14",X:"#00b649",Z:"#00f10e"},jalview_hydrophobicity:{A:"#ad0052",R:"#0000ff",N:"#0c00f3",D:"#0c00f3",C:"#c2003d",Q:"#0c00f3",E:"#0c00f3",G:"#6a0095",H:"#1500ea",I:"#ff0000",L:"#ea0015",K:"#0000ff",M:"#b0004f",F:"#cb0034",P:"#4600b9",S:"#5e00a1",T:"#61009e",W:"#5b00a4",Y:"#4f00b0",V:"#f60009",B:"#0c00f3",X:"#680097",Z:"#0c00f3"},jalview_prophelix:{A:"#e718e7",R:"#6f906f",N:"#1be41b",D:"#778877",C:"#23dc23",Q:"#926d92",E:"#ff00ff",G:"#00ff00",H:"#758a75",I:"#8a758a",L:"#ae51ae",K:"#a05fa0",M:"#ef10ef",F:"#986798",P:"#00ff00",S:"#36c936",T:"#47b847",W:"#8a758a",Y:"#21de21",V:"#857a85",B:"#49b649",X:"#758a75",Z:"#c936c9"},jalview_propstrand:{A:"#5858a7",R:"#6b6b94",N:"#64649b",D:"#2121de",C:"#9d9d62",Q:"#8c8c73",E:"#0000ff",G:"#4949b6",H:"#60609f",I:"#ecec13",L:"#b2b24d",K:"#4747b8",M:"#82827d",F:"#c2c23d",P:"#2323dc",S:"#4949b6",T:"#9d9d62",W:"#c0c03f",Y:"#d3d32c",V:"#ffff00",B:"#4343bc",X:"#797986",Z:"#4747b8"},jalview_propturn:{A:"#2cd3d3",R:"#708f8f",N:"#ff0000",D:"#e81717",C:"#a85757",Q:"#3fc0c0",E:"#778888",G:"#ff0000",H:"#708f8f",I:"#00ffff",L:"#1ce3e3",K:"#7e8181",M:"#1ee1e1",F:"#1ee1e1",P:"#f60909",S:"#e11e1e",T:"#738c8c",W:"#738c8c",Y:"#9d6262",V:"#07f8f8",B:"#f30c0c",X:"#7c8383",Z:"#5ba4a4"},jalview_taylor:{A:"#ccff00",R:"#0000ff",N:"#cc00ff",D:"#ff0000",C:"#ffff00",Q:"#ff00cc",E:"#ff0066",G:"#ff9900",H:"#0066ff",I:"#66ff00",L:"#33ff00",K:"#6600ff",M:"#00ff00",F:"#00ff66",P:"#ffcc00",S:"#ff3300",T:"#ff6600",W:"#00ccff",Y:"#00ffcc",V:"#99ff00"},jalview_zappo:{A:"#ffafaf",R:"#6464ff",N:"#00ff00",D:"#ff0000",C:"#ffff00",Q:"#00ff00",E:"#ff0000",G:"#ff00ff",H:"#6464ff",I:"#ffafaf",L:"#ffafaf",K:"#6464ff",M:"#ffafaf",F:"#ffc800",P:"#ff00ff",S:"#00ff00",T:"#00ff00",W:"#ffc800",Y:"#ffc800",V:"#ffafaf"},cinema:{H:"blue",K:"blue",R:"blue",D:"red",E:"red",S:"green",T:"green",N:"green",Q:"green",A:"white",V:"white",L:"white",I:"white",M:"white",F:"magenta",W:"magenta",Y:"magenta",P:"brown",G:"brown",C:"yellow",B:"gray",Z:"gray",X:"gray","-":"gray",".":"gray"}},ol=Gs(LU,([e,t])=>[e,Gs(t,([r,n])=>[r,it(n).toHex()])])});var p0,VM,FU,jM,$M=m(()=>{p0=p(Q(),1);Aa();GM();VM=p(Y(),1);m0();FU=(0,VM.observer)(function({model:e}){let{colorSchemeName:t}=e;return p0.default.createElement(Cn,{"data-testid":"color_scheme_menu",tooltip:"Color scheme",closeAfterItemClick:!0,anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"},menuItems:Object.keys(ol).map(r=>({label:r,type:"radio",checked:t===r,onClick:()=>{e.setColorSchemeName(r)}}))},p0.default.createElement(OM,null))}),jM=FU});var WM,YM,qM=m(()=>{"use client";we();WM=p(O(),1),YM=W((0,WM.jsx)("path",{d:"M19 3h-4.18C14.4 1.84 13.3 1 12 1s-2.4.84-2.82 2H5c-1.1 0-2 .9-2 2v14c0 1.1.9 2 2 2h14c1.1 0 2-.9 2-2V5c0-1.1-.9-2-2-2m-7 0c.55 0 1 .45 1 1s-.45 1-1 1-1-.45-1-1 .45-1 1-1m2 14H7v-2h7zm3-4H7v-2h10zm0-4H7V7h10z"}),"Assignment")});var zM,yd,g0=m(()=>{"use client";we();zM=p(O(),1),yd=W((0,zM.jsx)("path",{d:"M20 6h-8l-2-2H4c-1.1 0-1.99.9-1.99 2L2 18c0 1.1.9 2 2 2h16c1.1 0 2-.9 2-2V8c0-1.1-.9-2-2-2m0 12H4V8h16z"}),"FolderOpen")});var JM,KM,XM=m(()=>{"use client";we();JM=p(O(),1),KM=W((0,JM.jsx)("path",{d:"M3 18h18v-2H3zm0-5h18v-2H3zm0-7v2h18V6z"}),"Menu")});var h0,ZM,eR=m(()=>{"use client";we();h0=p(O(),1),ZM=W([(0,h0.jsx)("circle",{cx:"12",cy:"12",r:"3.2"},"0"),(0,h0.jsx)("path",{d:"M9 2 7.17 4H4c-1.1 0-2 .9-2 2v12c0 1.1.9 2 2 2h16c1.1 0 2-.9 2-2V6c0-1.1-.9-2-2-2h-3.17L15 2zm3 15c-2.76 0-5-2.24-5-5s2.24-5 5-5 5 2.24 5 5-2.24 5-5 5"},"1")],"PhotoCamera")});var tR,rR,nR=m(()=>{"use client";we();tR=p(O(),1),rR=W((0,tR.jsx)("path",{d:"M4.25 5.61C6.27 8.2 10 13 10 13v6c0 .55.45 1 1 1h2c.55 0 1-.45 1-1v-6s3.72-4.8 5.74-7.39c.51-.66.04-1.61-.79-1.61H5.04c-.83 0-1.3.95-.79 1.61"}),"FilterAlt")});var oR,iR,sR=m(()=>{"use client";we();oR=p(O(),1),iR=W((0,oR.jsx)("path",{d:"M15.5 14h-.79l-.28-.27C15.41 12.59 16 11.11 16 9.5 16 5.91 13.09 3 9.5 3S3 5.91 3 9.5 5.91 16 9.5 16c1.61 0 3.09-.59 4.23-1.57l.27.28v.79l5 4.99L20.49 19zm-6 0C7.01 14 5 11.99 5 9.5S7.01 5 9.5 5 14 7.01 14 9.5 11.99 14 9.5 14"}),"Search")});var aR,cR,lR=m(()=>{"use client";we();aR=p(O(),1),cR=W((0,aR.jsx)("path",{d:"M3 18h6v-2H3zM3 6v2h18V6zm0 7h12v-2H3z"}),"Sort")});var uR,fR,dR=m(()=>{"use client";we();uR=p(O(),1),fR=W((0,uR.jsx)("path",{d:"M12 4.5C7 4.5 2.73 7.61 1 12c1.73 4.39 6 7.5 11 7.5s9.27-3.11 11-7.5c-1.73-4.39-6-7.5-11-7.5M12 17c-2.76 0-5-2.24-5-5s2.24-5 5-5 5 2.24 5 5-2.24 5-5 5m0-8c-1.66 0-3 1.34-3 3s1.34 3 3 3 3-1.34 3-3-1.34-3-3-3"}),"Visibility")});var mR={};Bt(mR,{default:()=>UU});var ge,AR,he,xd,PU,OU,GU,UU,pR=m(()=>{ge=p(Q(),1),AR=p(Xe(),1),he=p(U(),1),xd=p(Y(),1),PU=(0,xd.observer)(function({model:e}){let{featureFilters:t}=e;return ge.default.createElement("div",null,ge.default.createElement(he.Button,{onClick:()=>{for(let r of t.keys())e.setFilter(r,!0)}},"Toggle all on"),ge.default.createElement(he.Button,{onClick:()=>{for(let r of t.keys())e.setFilter(r,!1)}},"Toggle all off"))}),OU=(0,xd.observer)(function({model:e}){let{tidyInterProAnnotationTypes:t,tidyInterProAnnotations:r,fillPalette:n}=e,o=new Map;for(let i of r)o.set(i.accession,(o.get(i.accession)??0)+1);return ge.default.createElement(ge.default.Fragment,null,ge.default.createElement(PU,{model:e}),ge.default.createElement(he.Table,{size:"small"},ge.default.createElement(he.TableHead,null,ge.default.createElement(he.TableRow,null,ge.default.createElement(he.TableCell,{padding:"checkbox"}),ge.default.createElement(he.TableCell,null,"color"),ge.default.createElement(he.TableCell,null,"accession"),ge.default.createElement(he.TableCell,null,"name"),ge.default.createElement(he.TableCell,null,"count"),ge.default.createElement(he.TableCell,null,"description"))),ge.default.createElement(he.TableBody,null,[...t.values()].map(({accession:i,name:s,description:a})=>ge.default.createElement(he.TableRow,{key:i},ge.default.createElement(he.TableCell,{padding:"checkbox"},ge.default.createElement(he.Checkbox,{checked:e.featureFilters.get(i)??!1,onChange:()=>{e.setFilter(i,!e.featureFilters.get(i))}})),ge.default.createElement(he.TableCell,null,ge.default.createElement("div",{style:{width:20,height:20,background:n[i]}})),ge.default.createElement(he.TableCell,null,i),ge.default.createElement(he.TableCell,null,s),ge.default.createElement(he.TableCell,null,o.get(i)),ge.default.createElement(he.TableCell,null,a))))))}),GU=(0,xd.observer)(function({onClose:e,model:t}){return ge.default.createElement(AR.Dialog,{onClose:()=>{e()},open:!0,title:"Feature filters",maxWidth:"xl"},ge.default.createElement(he.DialogContent,null,ge.default.createElement(OU,{model:t})))}),UU=GU});function HU(e){return typeof e=="string"?e:e?.message}async function il(e,t,r=gR.fetchAndMaybeUnzipText){let n=new AbortController;try{return await r(e,{signal:n.signal,statusCallback:o=>{let i=HU(o);t(i?{msg:i,onCancel:()=>{n.abort()}}:void 0)}})}finally{t(void 0)}}async function hR(e,t){let r=await fetch(e,t);if(!r.ok)throw new Error(`HTTP ${r.status} fetching ${e} ${await r.text()}`);return r}async function y0(e,t){return(await hR(e,t)).text()}async function Cd(e,t){return(await hR(e,t)).json()}function yR(e,t){return new Promise((r,n)=>{if(t?.aborted)n(new DOMException("Aborted","AbortError"));else{let o=setTimeout(r,e);t?.addEventListener("abort",()=>{clearTimeout(o),n(new DOMException("Aborted","AbortError"))})}})}function To(e){return e instanceof DOMException&&e.name==="AbortError"}var gR,Ed=m(()=>{gR=p(be(),1)});var ER={};Bt(ER,{default:()=>jU});var Re,xR,x0,Pe,CR,VU,jU,bR=m(()=>{Re=p(Q(),1),xR=p(Xe(),1),x0=p(be(),1),Pe=p(U(),1),CR=p(Y(),1);Ed();VU=(0,CR.observer)(function({handleClose:e,model:t}){let[r,n]=(0,Re.useState)(),[o,i]=(0,Re.useState)("file"),[s,a]=(0,Re.useState)("");return Re.default.createElement(xR.Dialog,{maxWidth:"xl",title:"Open protein domains from file",onClose:()=>{e()},open:!0},Re.default.createElement(Pe.DialogContent,null,Re.default.createElement("div",null,Re.default.createElement(Pe.Typography,null,"Open a JSON file of InterProScan results that you run remotely on EBI servers or locally"),Re.default.createElement("div",{style:{display:"flex",margin:30}},Re.default.createElement(Pe.FormControl,{component:"fieldset"},Re.default.createElement(Pe.RadioGroup,{value:o,onChange:c=>{i(c.target.value)}},Re.default.createElement(Pe.FormControlLabel,{value:"url",control:Re.default.createElement(Pe.Radio,null),label:"URL"}),Re.default.createElement(Pe.FormControlLabel,{value:"file",control:Re.default.createElement(Pe.Radio,null),label:"File"}))),o==="url"?Re.default.createElement("div",null,Re.default.createElement(Pe.Typography,null,"Open a InterProScan JSON file remote URL"),Re.default.createElement(Pe.TextField,{label:"URL",value:s,onChange:c=>{a(c.target.value)}})):null,o==="file"?Re.default.createElement("div",{style:{paddingTop:20}},Re.default.createElement(Pe.Typography,null,"Open a InterProScan JSON file file from your local drive"),Re.default.createElement(Pe.Button,{variant:"outlined",component:"label"},"Choose File",Re.default.createElement("input",{type:"file",hidden:!0,onChange:({target:c})=>{let l=c.files?.[0];l&&n(l)}}))):null))),Re.default.createElement(Pe.DialogActions,null,Re.default.createElement(Pe.Button,{variant:"contained",color:"primary",onClick:()=>{(async()=>{try{let c=r?JSON.parse(await r.text()):await Cd(s);t.setDomains(Object.fromEntries(c.results.map(l=>[l.xref[0]?.id,l]).filter(l=>l[0]!==void 0))),(0,x0.getSession)(t).notify("Loaded interproscan results","success")}catch(c){console.error(c),(0,x0.getSession)(t).notifyError(`${c}`,c)}finally{t.setStatus()}})(),e()}},"Open results")))}),jU=VU});function ma(e,t="node",r=0){let n=`${t}-${r}`;return{...e,id:n,name:e.name||n,children:e.children?.map((o,i)=>ma(o,`${n}-${i}`,r+1))||[]}}var C0=m(()=>{});var ur,pa=m(()=>{ur=class{width;getWidth(){return this.width??=this.getNames().reduce((t,r)=>Math.max(t,this.getRow(r).length),0),this.width}getTree(){return{id:"root",name:"root",noTree:!0,children:this.getNames().map(t=>({id:t,children:[],name:t}))}}getRowData(t){}getStructures(){return{}}getHeader(){return{}}get alignmentNames(){return[]}get seqConsensus(){}get secondaryStructureConsensus(){}get tracks(){return[]}}});function sl(e){let t=[],r=new Set;for(let n of e.split(">")){if(!/\S/.test(n))continue;let o=n.indexOf(`
+`);if(o===-1)continue;let i=n.slice(0,o).replace(/\r$/,""),s=i.indexOf(" "),a=s===-1?i:i.slice(0,s);!a||r.has(a)||(r.add(a),t.push({id:a,seq:n.slice(o+1).replaceAll(/\s/g,"")}))}return t}var E0=m(()=>{});function JU(e){return e>=YU&&e<=qU}function KU(e){return e>=$U&&e<=WU||e===zU}function wR(e){let t=[],r=[""];for(let n of e){let o=n.charCodeAt(0);KU(o)?(t.push(n),r.push("")):JU(o)&&(r[r.length-1]+=n.toUpperCase())}return{matches:t,inserts:r}}function XU(e,t){let r=e.map(wR),n=Math.max(...r.map(s=>s.matches.length),0),o=new Array(n+1).fill(0);for(let{inserts:s}of r)for(let[a,c]of s.entries())o[a]=Math.max(o[a],c.length);let i={};for(let[s,{matches:a,inserts:c}]of r.entries()){let l=[];for(let u=0;u<=n;u++){let d=c[u]??"";l.push(d,".".repeat(o[u]-d.length)),u<n&&l.push(a[u]??"-")}i[t[s]]=l.join("")}return i}var $U,WU,YU,qU,zU,Kn,b0=m(()=>{pa();E0();$U=65,WU=90,YU=97,qU=122,zU=45;Kn=class extends ur{MSA;orderedNames;constructor(t){super();let r=sl(t);this.orderedNames=r.map(n=>n.id),this.MSA={seqdata:XU(r.map(n=>n.seq),this.orderedNames)}}static sniff(t){if(!t.startsWith(">"))return!1;let r=sl(t).map(s=>s.seq).filter(s=>!!s);if(r.length<2||new Set(r.map(s=>s.length)).size===1)return!1;let n=r.map(wR),o=n.some(s=>s.inserts.some(a=>!!a)),i=new Set(n.map(s=>s.matches.length)).size===1;return o&&i}getMSA(){return this.MSA}getNames(){return this.orderedNames}getRow(t){return this.MSA.seqdata[t]??""}}});function ZU(e){let t=/\(?(\d+(\.\d+)+)\)?/.exec(e);return t&&t.length>1?t[1]:""}function SR(e){let t=["CLUSTAL","PROBCONS","MUSCLE","MSAPROBS","Kalign"];t.some(n=>e.startsWith(n))||console.warn(`${e} is not a known CLUSTAL header: ${t.join(",")}, proceeding but could indicate an issue`);let r=ZU(e);return{info:e,version:r}}function w0(e){let t=e.next();for(;!t.done&&t.value.trim()==="";)t=e.next();return t.value}function eH(e){let t=e.split(/\s+/),r=e.slice(t[0].length),n=t[0].length+r.indexOf(t[1]),o=n+t[1].length;return[n,o]}function IR(e){let t=w0(e),r=[],n="";if(!t)return;for(;t;)t.startsWith(" ")?n=t:r.push(t),t=e.next().value;let[o,i]=eH(r[0]),a=r.map(d=>d.split(/\s+/)).map(d=>d[0]),c=r.map(d=>d.slice(o,i)),l=n.slice(o,i),u=c[0].length-l.length;return u&&(l+=" ".repeat(u)),{ids:a,seqs:c,consensus:l}}function vR(e){let t,r=IR(e);if(r!==void 0)for(;t=IR(e);){for(let n=0;n<t.seqs.length;n++)r.seqs[n]+=t.seqs[n];r.consensus+=t.consensus}return r}var BR=m(()=>{});function tH(e){let t=w0(e);if(!t)throw new Error("Empty file received");let r=SR(t),n=vR(e);if(n===void 0)throw new Error("No blocks parsed");let o=n.seqs.map((s,a)=>({id:n.ids[a],seq:s})),{consensus:i}=n;if(i.length!==o[0].seq.length)throw new Error(`Consensus length != sequence length. Con ${i.length} seq ${o[0].seq.length}`);return{consensus:i,alns:o,header:r}}function TR(e){let t=e.split(`
+`)[Symbol.iterator]();return tH(t)}var MR=m(()=>{BR()});var Mo,I0=m(()=>{MR();pa();Mo=class extends ur{MSA;byName;constructor(t){super(),this.MSA=TR(t),this.byName=new Map;for(let r of this.MSA.alns)this.byName.has(r.id)||this.byName.set(r.id,r.seq)}getMSA(){return this.MSA}getRow(t){return this.byName.get(t)??""}getHeader(){return this.MSA.header}getNames(){return this.MSA.alns.map(t=>t.id)}get seqConsensus(){return this.MSA.consensus}}});function RR(e){let t=e.split(`
+`).map(i=>i.trim()).filter(i=>!!i),r=[],n=[];for(let i of t)if(i.startsWith("SEQ"))r.push(i);else{if(i.startsWith("DATA"))continue;if(i.startsWith("//"))break;n.push(i)}let o=r.map(i=>{let[,s,a,c,l,u,d,A,f]=i.split(" ");return{species:s,protein:a,chr:c,start:+l,end:+u,strand:+d,geneId:A,unknown:f,seq:""}});for(let i of n)for(let s=0;s<r.length;s++)o[s].seq+=i[s];return o}function bd(e){let t=e.split(`
+`).map(i=>i.trim()).filter(i=>!!i),r=[],n="";for(let i of t)if(i.startsWith("SEQ"))r.push(i);else{if(i.startsWith("DATA"))continue;if(i.startsWith("//"))break;n=i}let o=r.map(i=>{let[,s,a,c,l,u,d,A,f]=i.split(" ");return{species:s,protein:a,chr:c,start:+l,end:+u,strand:+d,geneId:A,unknown:f}});return{tree:n,seqs:o}}var S0=m(()=>{});var Ro,v0=m(()=>{S0();pa();Ro=class extends ur{MSA;byName;constructor(t){super(),this.MSA=RR(t),this.byName=new Map;for(let r of this.MSA)this.byName.has(r.protein)||this.byName.set(r.protein,r.seq)}getMSA(){return this.MSA}getRow(t){return this.byName.get(t)??""}getNames(){return this.MSA.map(t=>t.protein)}}});var Qo,B0=m(()=>{pa();E0();Qo=class extends ur{MSA;orderedNames;constructor(t){super();let r=sl(t),n={},o={};for(let{id:i,seq:s}of r)n[i]=s,i.includes(":")&&(o[i.replaceAll(":","_")]=i);this.orderedNames=r.map(i=>i.id),this.MSA={seqdata:n,colonNormalized:o}}getMSA(){return this.MSA}getNames(){return this.orderedNames}getRow(t){return this.MSA.seqdata[t]??this.MSA.seqdata[this.MSA.colonNormalized[t]??""]??""}}});function Mi(e){return Cf(e,{postParenNumeric:"name"})}var T0=m(()=>{dg()});function QR(){return{gf:{},gc:{},gs:{},gr:{},seqname:[],seqdata:{}}}function al(e,t){if(e)return e;if(t)throw new Error("No format header: # STOCKHOLM 1.0");return QR()}function cl(e){return _R.test(e)}function kR(e,t){let r=t??{},n=[],o=null,i=e.split(`
+`);for(let s of i){let a;if(_R.test(s))o=QR();else if(rH.test(s))o&&n.push(o),o=null;else if(a=nH.exec(s))o=al(o,!!r.strict),(o.gf[a[1]]??=[]).push(a[2]);else if(a=oH.exec(s))o=al(o,!!r.strict),o.gc[a[1]]=(o.gc[a[1]]??"")+a[2];else if(a=iH.exec(s)){o=al(o,!!r.strict);let c=o.gs[a[2]]??={};(c[a[1]]??=[]).push(a[3])}else if(a=sH.exec(s)){o=al(o,!!r.strict);let c=o.gr[a[2]]??={};c[a[1]]=(c[a[1]]??"")+a[3]}else if(a=aH.exec(s)){o=al(o,!!r.strict);let c=a[1],l=a[2];o.seqdata[c]||(o.seqdata[c]="",o.seqname.push(c)),o.seqdata[c]+=l}else if(cH.test(s)&&r.strict)throw new Error("Malformed line")}return o&&n.push(o),n}var _R,rH,nH,oH,iH,sH,aH,cH,M0=m(()=>{_R=/^# STOCKHOLM 1.0/,rH=/^\/\/\s*$/,nH=/^#=GF\s+(\S+)\s+(.*?)\s*$/,oH=/^#=GC\s+(\S+)\s+(.*?)\s*$/,iH=/^#=GS\s+(\S+)\s+(\S+)\s+(.*?)\s*$/,sH=/^#=GR\s+(\S+)\s+(\S+)\s+(.*?)\s*$/,aH=/^\s*([^#\s]\S*)\s+(\S+)\s*$/,cH=/\S/});var _o,R0=m(()=>{C0();pa();T0();M0();M0();_o=class extends ur{data;MSA;constructor(t,r){super();let n=kR(t);this.data=n;let o=n[r]??n[0];if(!o)throw new Error("No alignments found in Stockholm file");this.MSA=o}getMSA(){return this.MSA}getRow(t){return this.MSA.seqdata[t]??""}get alignmentNames(){return this.data.map((t,r)=>t.gf.DE?.[0]??`Alignment ${r+1}`)}getHeader(){let t=this.MSA.gs.AC??{},r=this.MSA.gs.DR??{};return{General:this.MSA.gf,Accessions:Object.fromEntries(Object.entries(t).map(([n,o])=>[n,o[0]])),Dbxref:Object.fromEntries(Object.entries(r).map(([n,o])=>[n,o.join("; ")]))}}getRowData(t){return{name:t,accession:this.MSA.gs.AC?.[t]?.[0],dbxref:this.MSA.gs.DR?.[t]?.join("; ")}}getNames(){return this.MSA.seqname}getStructures(){let t=/PDB; +(\S+) +(\S); ([0-9]+)-([0-9]+)/,r=this.MSA.gs.DR??{},n={};for(let[o,i]of Object.entries(r))for(let s of i){let a=t.exec(s);a&&(n[o]??=[]).push({pdb:a[1].toLowerCase(),chain:a[2],startPos:+a[3],endPos:+a[4]})}return n}getTree(){let t=this.MSA.gf.NH?.[0];return t?ma(Mi(t)):super.getTree()}get seqConsensus(){return this.MSA.gc.seq_cons}get secondaryStructureConsensus(){return this.MSA.gc.SS_cons}get tracks(){return[{id:"seqConsensus",name:"Sequence consensus",data:this.seqConsensus,customColorScheme:{}},{id:"secondaryStruct",name:"Secondary-structure",data:this.secondaryStructureConsensus,customColorScheme:{"<":"lightblue","(":"lightblue","[":"lightblue","{":"lightblue",">":"pink",")":"pink","]":"pink","}":"pink"}}]}}});function Q0(e,t=0,r){return r==="stockholm"?new _o(e,t):r==="a3m"?new Kn(e):r==="fasta"?new Qo(e):r==="emf"?new Ro(e):r==="clustal"?new Mo(e):cl(e)?new _o(e,t):Kn.sniff(e)?new Kn(e):e.startsWith(">")?new Qo(e):e.startsWith("SEQ")?new Ro(e):new Mo(e)}function ll(e){return e.replaceAll(/[.-]/g,"")}var DR=m(()=>{b0();I0();v0();B0();R0();S0();T0();b0();I0();v0();B0();R0()});function lH(e){try{return decodeURIComponent(e)}catch{return e}}function uH(e){return e?Object.fromEntries(e.split(";").map(t=>t.trim()).filter(t=>!!t).map(t=>{let r=t.indexOf("="),n=(r===-1?t:t.slice(0,r)).trim(),o=r===-1?void 0:t.slice(r+1);return[n,o?o.split(",").map(i=>lH(i).trim()).join(" "):void 0]}).filter(([t])=>t!=="")):{}}function wd(e){return e?e.split(`
+`).map(t=>t.trim()).filter(t=>!!t&&!t.startsWith("#")).map(t=>{let r=t.split("	"),[n,o,i,s,a,c,l,u]=r,d=r[8];return{...uH(d),seq_id:n??"",source:o??"",type:i??"",start:Number(s)||0,end:Number(a)||0,score:Number(c)||0,strand:l??".",phase:u??"."}}):[]}var NR=m(()=>{});function dH({type:e,strand:t}){let r=t==="+"?1:t==="-"?-1:void 0;return fH.has(e)?r:void 0}function Id(e){let t=Map.groupBy(e,n=>n.seq_id),r={};for(let[n,o]of t){let i=new Map,s=new Map;for(let a of o){let c=a.Name||a.ID||`${a.source}_${a.start}_${a.end}`,l=a.signature_desc||a.Name||c,u=a.Ontology_term||a.description||a.Note||l;s.has(c)||s.set(c,{name:l,description:u,accession:c,featureType:a.type});let d=i.get(c);d||(d=[],i.set(c,d)),d.push({start:a.start,end:a.end,strand:dH(a)})}r[n]={matches:[...i].map(([a,c])=>({signature:{entry:s.get(a)},locations:c})),xref:[{id:n}]}}return r}var fH,LR=m(()=>{fH=new Set(["gene","pseudogene","mRNA","transcript","primary_transcript","ncRNA","tRNA","rRNA","snRNA","snoRNA","miRNA","lnc_RNA"])});var FR=m(()=>{});var PR=m(()=>{NR();LR();FR()});var Sd=m(()=>{C0();DR();PR()});async function gH({seq:e,onProgress:t,onJobId:r,programs:n,model:o,signal:i}){let s=await y0(`${_0}/iprscan5/run`,{method:"POST",body:new URLSearchParams({email:"colin.diesh@gmail.com",sequence:e,programs:n.join(",")}),signal:i});r?.(s),await yH({jobId:s,onProgress:t,signal:i}),await xH({jobId:s,model:o,onProgress:t,signal:i})}function hH(e,t){return Cd(`${_0}/iprscan5/result/${e}/json`,{signal:t})}async function yH({onProgress:e,jobId:t,signal:r}){let n=`${_0}/iprscan5/status/${t}`,o=360;try{let i=!1;for(let s=0;s<o&&!i;s++){for(let c=0;c<10;c++)await yR(1e3,r),e({msg:`Checking status ${10-c}`,url:n});let a=(await y0(n,{signal:r})).trim();if(a==="FINISHED")i=!0;else if(a==="FAILURE"||a==="ERROR"||a==="NOT_FOUND")throw new Error(`InterProScan job ${t} ended with status: ${a}`)}if(!i)throw new Error(`InterProScan job ${t} did not finish after ${o} status checks`)}finally{e()}}async function OR({algorithm:e,seq:t,programs:r,onJobId:n,onProgress:o,model:i,signal:s}){try{if(o({msg:`Launching ${e} MSA`}),e==="interproscan")await gH({seq:t,onJobId:n,onProgress:o,programs:r,model:i,signal:s});else throw new Error("unknown algorithm")}catch(a){if(To(a))(0,ul.getSession)(i).notify("Cancelled InterProScan query","info");else throw a}finally{o()}}async function xH({jobId:e,model:t,onProgress:r,signal:n}){try{r({msg:`Downloading results of ${e} (for larger sequences this can be slow, click status to download and upload in the manual tab)`,url:`https://www.ebi.ac.uk/Tools/services/rest/iprscan5/result/${e}/json`});let o=await hH(e,n);t.setDomains(Object.fromEntries(o.results.map(i=>[i.xref[0]?.id,i]).filter(i=>i[0]!==void 0))),(0,ul.getSession)(t).notify(`Loaded interproscan ${e} results`,"success")}catch(o){To(o)?(0,ul.getSession)(t).notify("Cancelled InterProScan query","info"):(console.error(o),(0,ul.getSession)(t).notifyError(`${o}`,o))}finally{r()}}var ul,_0,GR=m(()=>{ul=p(be(),1);Ed();_0="https://www.ebi.ac.uk/Tools/services/rest"});var jR={};Bt(jR,{default:()=>EH});var Oe,UR,HR,fr,VR,CH,EH,$R=m(()=>{Oe=p(Q(),1),UR=p(Xe(),1),HR=p(be(),1),fr=p(U(),1),VR=p(Y(),1);Sd();GR();CH=(0,VR.observer)(function({handleClose:e,model:t}){let[r,n]=(0,Oe.useState)([{name:"NCBIfam",description:"NCBI RefSeq FAMs including TIGRFAMs",category:"Families, domains, sites & repeats",checked:!0},{name:"SFLD",description:"Structure function linkage database",category:"Families, domains, sites & repeats",checked:!0},{name:"Phobius",checked:!0,description:"A combined transmembrane topology and signal peptide predictor",category:"Other sequence features"},{name:"SignalP",checked:!0,category:"Other sequence features"},{name:"SignalP_EUK",category:"Other category",checked:!0},{name:"SignalP_GRAM_POSITIVE",category:"Other category",checked:!0},{name:"SignalP_GRAM_NEGATIVE",checked:!0,category:"Other category"},{name:"SuperFamily",category:"Structural domains",checked:!0},{name:"Panther",category:"Families, domains, sites & repeats",checked:!0},{name:"Gene3d",category:"Structural domains",checked:!0},{name:"HAMAP",category:"Families, domains, sites & repeats",checked:!0},{name:"PrositeProfiles",category:"Families, domains, sites & repeats",checked:!0},{name:"PrositePatterns",category:"Families, domains, sites & repeats",checked:!0},{name:"Coils",category:"Other sequence features",checked:!0},{name:"SMART",category:"Families, domains, sites & repeats",checked:!0},{name:"CDD",description:"Conserved Domains Database",category:"Families, domains, sites & repeats",checked:!0},{name:"PRINTS",category:"Families, domains, sites & repeats",checked:!0},{name:"PfamA",category:"Families, domains, sites & repeats",checked:!0},{name:"MobiDBLite",checked:!0,category:"Other sequence features"},{name:"PIRSF",checked:!0,category:"Other category"},{name:"TMHMM",checked:!0,category:"Other sequence features"},{name:"AntiFam",checked:!0,category:"Other category"},{name:"FunFam",checked:!0,category:"Other category"},{name:"PIRSR",checked:!0,category:"Families, domains, sites & repeats"}]),o=r.filter(a=>a.checked).map(a=>a.name),[i,s]=(0,Oe.useState)(!1);return Oe.default.createElement(UR.Dialog,{maxWidth:"xl",title:"Query InterProScan API for domains",onClose:()=>{e()},open:!0},Oe.default.createElement(fr.DialogContent,null,Oe.default.createElement(fr.Typography,null,"This will run InterProScan via the InterProScan API on all rows of the current MSA"),Oe.default.createElement(fr.Button,{onClick:()=>{s(!i)}},i?"Hide":"Show"," advanced options"),i?Oe.default.createElement("div",null,Oe.default.createElement(fr.Typography,null,"Select algorithms for InterProScan to run"),Oe.default.createElement("div",null,Oe.default.createElement(fr.Button,{variant:"contained",color:"secondary",onClick:()=>{n(r.map(a=>({...a,checked:!1})))}},"Select none"),Oe.default.createElement(fr.Button,{variant:"contained",color:"primary",onClick:()=>{n(r.map(a=>({...a,checked:!0})))}},"Select all")),Oe.default.createElement("table",null,Oe.default.createElement("tbody",null,r.toSorted((a,c)=>a.category.localeCompare(c.category)).map(({name:a,checked:c,category:l})=>Oe.default.createElement("tr",{key:a},Oe.default.createElement("td",null,Oe.default.createElement("input",{type:"checkbox",key:a,checked:c,onChange:()=>{n(r.map(u=>u.name===a?{...u,checked:!u.checked}:u))}})),Oe.default.createElement("td",null,a),Oe.default.createElement("td",null,l)))))):null),Oe.default.createElement(fr.DialogActions,null,Oe.default.createElement(fr.Button,{variant:"contained",color:"secondary",onClick:()=>{e()}},"Cancel"),Oe.default.createElement(fr.Button,{variant:"contained",color:"primary",onClick:()=>{let a=new AbortController;(async()=>{try{let{rows:c}=t;if(c.length>140)throw new Error("Too many sequences, please run InterProScan offline");await OR({algorithm:"interproscan",programs:o,seq:c.map(l=>[l[0],ll(l[1])]).filter(l=>!!l[1]).map(l=>`>${l[0]}
 ${l[1]}`).join(`
-`),onProgress:l=>{t.setStatus(l?{...l,onCancel:()=>{a.abort()}}:void 0)},model:t,signal:a.signal})}catch(c){console.error(c),(0,_R.getSession)(t).notifyError(`${c}`,c)}finally{t.setStatus()}})(),e()}},"Send sequences to InterProScan")))}),KU=JU});function LR({model:e}){let{showDomains:t,actuallyShowDomains:r,subFeatureRows:n,noDomains:o}=e;return[{label:"Open domains...",icon:cd,onClick:()=>{e.queueDialog(i=>[ZU,{handleClose:i,model:e}])}},{label:"Query InterProScan for domains...",icon:WM,onClick:()=>{e.queueDialog(i=>[e9,{handleClose:i,model:e}])}},{label:`Show domains${o?" (no domains loaded)":""}`,disabled:o,icon:XM,checked:r?t:!1,type:"checkbox",onClick:()=>{e.setShowDomains(!t)}},{label:`Use sub-row layout${o?" (no domains loaded)":""}`,disabled:o,checked:r?n:!1,icon:zM,type:"checkbox",onClick:()=>{e.setSubFeatureRows(!n)}},{label:`Filter domains${o?" (no domains loaded)":""}`,icon:VM,disabled:o,onClick:()=>{e.queueDialog(i=>[XU,{onClose:i,model:e}])}}]}var pd,XU,ZU,e9,PR=m(()=>{pd=p(Q(),1);jM();a0();YM();JM();ZM();XU=(0,pd.lazy)(()=>Promise.resolve().then(()=>(rR(),tR))),ZU=(0,pd.lazy)(()=>Promise.resolve().then(()=>(lR(),cR))),e9=(0,pd.lazy)(()=>Promise.resolve().then(()=>(NR(),DR)))});var t9,S0,FR=m(()=>{t9={50:"#ffebee",100:"#ffcdd2",200:"#ef9a9a",300:"#e57373",400:"#ef5350",500:"#f44336",600:"#e53935",700:"#d32f2f",800:"#c62828",900:"#b71c1c",A100:"#ff8a80",A200:"#ff5252",A400:"#ff1744",A700:"#d50000"},S0=t9});var r9,v0,OR=m(()=>{r9={50:"#e3f2fd",100:"#bbdefb",200:"#90caf9",300:"#64b5f6",400:"#42a5f5",500:"#2196f3",600:"#1e88e5",700:"#1976d2",800:"#1565c0",900:"#0d47a1",A100:"#82b1ff",A200:"#448aff",A400:"#2979ff",A700:"#2962ff"},v0=r9});var n9,B0,GR=m(()=>{n9={50:"#e8f5e9",100:"#c8e6c9",200:"#a5d6a7",300:"#81c784",400:"#66bb6a",500:"#4caf50",600:"#43a047",700:"#388e3c",800:"#2e7d32",900:"#1b5e20",A100:"#b9f6ca",A200:"#69f0ae",A400:"#00e676",A700:"#00c853"},B0=n9});var o9,T0,UR=m(()=>{o9={50:"#fff3e0",100:"#ffe0b2",200:"#ffcc80",300:"#ffb74d",400:"#ffa726",500:"#ff9800",600:"#fb8c00",700:"#f57c00",800:"#ef6c00",900:"#e65100",A100:"#ffd180",A200:"#ffab40",A400:"#ff9100",A700:"#ff6d00"},T0=o9});var i9,Lo,HR=m(()=>{i9={50:"#fafafa",100:"#f5f5f5",200:"#eeeeee",300:"#e0e0e0",400:"#bdbdbd",500:"#9e9e9e",600:"#757575",700:"#616161",800:"#424242",900:"#212121",A100:"#f5f5f5",A200:"#eeeeee",A400:"#bdbdbd",A700:"#616161"},Lo=i9});var VR=m(()=>{FR();OR();GR();UR();HR()});var YR=K((ice,WR)=>{"use strict";var s9=function(t){return a9(t)&&!c9(t)};function a9(e){return!!e&&typeof e=="object"}function c9(e){var t=Object.prototype.toString.call(e);return t==="[object RegExp]"||t==="[object Date]"||f9(e)}var l9=typeof Symbol=="function"&&Symbol.for,u9=l9?Symbol.for("react.element"):60103;function f9(e){return e.$$typeof===u9}function d9(e){return Array.isArray(e)?[]:{}}function al(e,t){return t.clone!==!1&&t.isMergeableObject(e)?ha(d9(e),e,t):e}function A9(e,t,r){return e.concat(t).map(function(n){return al(n,r)})}function m9(e,t){if(!t.customMerge)return ha;var r=t.customMerge(e);return typeof r=="function"?r:ha}function p9(e){return Object.getOwnPropertySymbols?Object.getOwnPropertySymbols(e).filter(function(t){return Object.propertyIsEnumerable.call(e,t)}):[]}function jR(e){return Object.keys(e).concat(p9(e))}function $R(e,t){try{return t in e}catch{return!1}}function g9(e,t){return $R(e,t)&&!(Object.hasOwnProperty.call(e,t)&&Object.propertyIsEnumerable.call(e,t))}function h9(e,t,r){var n={};return r.isMergeableObject(e)&&jR(e).forEach(function(o){n[o]=al(e[o],r)}),jR(t).forEach(function(o){g9(e,o)||($R(e,o)&&r.isMergeableObject(t[o])?n[o]=m9(o,r)(e[o],t[o],r):n[o]=al(t[o],r))}),n}function ha(e,t,r){r=r||{},r.arrayMerge=r.arrayMerge||A9,r.isMergeableObject=r.isMergeableObject||s9,r.cloneUnlessOtherwiseSpecified=al;var n=Array.isArray(t),o=Array.isArray(e),i=n===o;return i?n?r.arrayMerge(e,t,r):h9(e,t,r):al(t,r)}ha.all=function(t,r){if(!Array.isArray(t))throw new Error("first argument should be an array");return t.reduce(function(n,o){return ha(n,o,r)},{})};var y9=ha;WR.exports=y9});function JR(){return{palette:{...gd,mode:void 0},components:{MuiLink:{styleOverrides:{root:({theme:e})=>({color:e.palette.tertiary.main})}}}}}function k9(){return{...JR(),name:"Default (from config)"}}function D9(){return{...JR(),name:"Light (stock)"}}function N9(){return{name:"Dark (stock)",palette:{...gd,mode:"dark"},components:{MuiAppBar:{defaultProps:{enableColorOnDark:!0},styleOverrides:{root:({theme:e})=>e.palette.primary.main}}}}}function L9(){return{name:"Dark (minimal)",palette:{...gd,mode:"dark",primary:{main:Lo[700]},secondary:{main:Lo[800]},tertiary:Ue.palette.augmentColor({color:{main:Lo[900]}})}}}function P9(){return{name:"Light (minimal)",palette:{...gd,primary:{main:Lo[900]},secondary:{main:Lo[800]},tertiary:Ue.palette.augmentColor({color:{main:Lo[900]}})}}}var zR,x9,Ue,C9,b9,E9,qR,ace,w9,I9,S9,v9,B9,T9,M9,R9,Q9,_9,gd,cce,KR=m(()=>{zR=p(U(),1);VR();x9=p(YR(),1),Ue=(0,zR.createTheme)(),C9=Ue.palette.augmentColor({color:{main:"#0D233F"}}),b9=Ue.palette.augmentColor({color:{main:"#721E63"}}),E9=Ue.palette.augmentColor({color:{main:"#135560"}}),qR=Ue.palette.augmentColor({color:{main:"#FFB11D"}}),ace=Ue.palette.augmentColor({color:{main:"#aaa"}}),w9={A:Ue.palette.augmentColor({color:B0}),C:Ue.palette.augmentColor({color:v0}),G:Ue.palette.augmentColor({color:T0}),T:Ue.palette.augmentColor({color:S0})},I9=[null,Ue.palette.augmentColor({color:{main:"#FF8080"}}),Ue.palette.augmentColor({color:{main:"#80FF80"}}),Ue.palette.augmentColor({color:{main:"#8080FF"}}),Ue.palette.augmentColor({color:{main:"#8080FF"}}),Ue.palette.augmentColor({color:{main:"#80FF80"}}),Ue.palette.augmentColor({color:{main:"#FF8080"}})],S9=[null,Ue.palette.augmentColor({color:{main:"#8f8f8f"}}),Ue.palette.augmentColor({color:{main:"#adadad"}}),Ue.palette.augmentColor({color:{main:"#d8d8d8"}}),Ue.palette.augmentColor({color:{main:"#d8d8d8"}}),Ue.palette.augmentColor({color:{main:"#adadad"}}),Ue.palette.augmentColor({color:{main:"#8f8f8f"}})],v9="#e22",B9="#3e3",T9="#800080",M9="#808080",R9="#f00",Q9="#00f",_9="#97b8c9",gd={primary:C9,secondary:b9,tertiary:E9,quaternary:qR,highlight:qR,stopCodon:v9,startCodon:B9,insertion:T9,deletion:M9,softclip:Q9,hardclip:R9,bases:w9,frames:S9,framesCDS:I9,skip:_9};cce={default:k9(),lightStock:D9(),lightMinimal:P9(),darkMinimal:L9(),darkStock:N9()}});var XR=m(()=>{});function hd(){return typeof window<"u"}function Po(e){return R0(e)?(e.nodeName||"").toLowerCase():"#document"}function Qt(e){var t;return(e==null||(t=e.ownerDocument)==null?void 0:t.defaultView)||window}function ro(e){var t;return(t=(R0(e)?e.ownerDocument:e.document)||window.document)==null?void 0:t.documentElement}function R0(e){return hd()?e instanceof Node||e instanceof Qt(e).Node:!1}function _t(e){return hd()?e instanceof Element||e instanceof Qt(e).Element:!1}function zr(e){return hd()?e instanceof HTMLElement||e instanceof Qt(e).HTMLElement:!1}function cl(e){return!hd()||typeof ShadowRoot>"u"?!1:e instanceof ShadowRoot||e instanceof Qt(e).ShadowRoot}function ll(e){let{overflow:t,overflowX:r,overflowY:n,display:o}=kr(e);return/auto|scroll|overlay|hidden|clip/.test(t+n+r)&&o!=="inline"&&o!=="contents"}function ZR(e){return/^(table|td|th)$/.test(Po(e))}function ul(e){try{if(e.matches(":popover-open"))return!0}catch{}try{return e.matches(":modal")}catch{return!1}}function yd(e){let t=_t(e)?kr(e):e;return Ri(t.transform)||Ri(t.translate)||Ri(t.scale)||Ri(t.rotate)||Ri(t.perspective)||!fl()&&(Ri(t.backdropFilter)||Ri(t.filter))||F9.test(t.willChange||"")||O9.test(t.contain||"")}function e2(e){let t=to(e);for(;zr(t)&&!Qi(t);){if(yd(t))return t;if(ul(t))return null;t=to(t)}return null}function fl(){return M0==null&&(M0=typeof CSS<"u"&&CSS.supports&&CSS.supports("-webkit-backdrop-filter","none")),M0}function Qi(e){return/^(html|body|#document)$/.test(Po(e))}function kr(e){return Qt(e).getComputedStyle(e)}function dl(e){return _t(e)?{scrollLeft:e.scrollLeft,scrollTop:e.scrollTop}:{scrollLeft:e.scrollX,scrollTop:e.scrollY}}function to(e){if(Po(e)==="html")return e;let t=e.assignedSlot||e.parentNode||cl(e)&&e.host||ro(e);return cl(t)?t.host:t}function t2(e){let t=to(e);return Qi(t)?(e.ownerDocument||e).body:zr(t)&&ll(t)?t:t2(t)}function ya(e,t,r){var n;t===void 0&&(t=[]),r===void 0&&(r=!0);let o=t2(e),i=o===((n=e.ownerDocument)==null?void 0:n.body),s=Qt(o);if(i){let a=xd(s);return t.concat(s,s.visualViewport||[],ll(o)?o:[],a&&r?ya(a):[])}else return t.concat(o,ya(o,[],r))}function xd(e){return e.parent&&Object.getPrototypeOf(e.parent)?e.frameElement:null}var F9,O9,Ri,M0,Cd=m(()=>{F9=/transform|translate|scale|rotate|perspective|filter/,O9=/paint|layout|strict|content/,Ri=e=>!!e&&e!=="none"});function Q0(e,t){return typeof e=="function"?e(t):e}function _0(e){return e.split("-")[0]}function k0(e){return e.split("-")[1]}function r2(e){return e==="x"?"y":"x"}function n2(e){return e==="y"?"height":"width"}function Ed(e){let t=e[0];return t==="t"||t==="b"?"y":"x"}function o2(e){return r2(Ed(e))}function G9(e){var t,r,n,o;return{top:(t=e.top)!=null?t:0,right:(r=e.right)!=null?r:0,bottom:(n=e.bottom)!=null?n:0,left:(o=e.left)!=null?o:0}}function i2(e){return typeof e!="number"?G9(e):{top:e,right:e,bottom:e,left:e}}function ki(e){let{x:t,y:r,width:n,height:o}=e;return{width:n,height:o,top:r,left:t,right:t+n,bottom:r+o,x:t,y:r}}var bd,_i,Al,Bn,wd=m(()=>{bd=Math.min,_i=Math.max,Al=Math.round,Bn=e=>({x:e,y:e})});function a2(e,t){if(!e||!t)return!1;let r=t.getRootNode==null?void 0:t.getRootNode();if(e.contains(t))return!0;if(r&&cl(r)){let n=t;for(;n;){if(e===n)return!0;n=n.parentNode||n.host}}return!1}function c2(e){return"composedPath"in e?e.composedPath()[0]:e.target}function l2(e,t){let r=["mouse","pen"];return t||r.push("",void 0),r.includes(e)}function Id(e){let t=ml.useRef(()=>{});return $9(()=>{t.current=e}),ml.useCallback(function(){for(var r=arguments.length,n=new Array(r),o=0;o<r;o++)n[o]=arguments[o];return t.current==null?void 0:t.current(...n)},[])}var ml,s2,U9,H9,pl,V9,j9,$9,u2=m(()=>{Cd();ml=p(Q(),1),s2=p(Q(),1);U9=typeof document<"u",H9=function(){},pl=U9?s2.useLayoutEffect:H9,V9={...ml},j9=V9.useInsertionEffect,$9=j9||(e=>e())});function f2(e,t,r){let{reference:n,floating:o}=e,i=Ed(t),s=o2(t),a=n2(s),c=_0(t),l=i==="y",u=n.x+n.width/2-o.width/2,d=n.y+n.height/2-o.height/2,A=n[a]/2-o[a]/2,f;switch(c){case"top":f={x:u,y:n.y-o.height};break;case"bottom":f={x:u,y:n.y+n.height};break;case"right":f={x:n.x+n.width,y:d};break;case"left":f={x:n.x-o.width,y:d};break;default:f={x:n.x,y:n.y}}let g=k0(t);return g&&(f[s]+=A*(g==="end"?1:-1)*(r&&l?-1:1)),f}async function d2(e,t){var r;t===void 0&&(t={});let{x:n,y:o,platform:i,rects:s,elements:a,strategy:c}=e,{boundary:l="clippingAncestors",rootBoundary:u="viewport",elementContext:d="floating",altBoundary:A=!1,padding:f=0}=Q0(t,e),g=i2(f),y=a[A?d==="floating"?"reference":"floating":d],E=ki(await i.getClippingRect({element:(r=await(i.isElement==null?void 0:i.isElement(y)))==null||r?y:y.contextElement||await(i.getDocumentElement==null?void 0:i.getDocumentElement(a.floating)),boundary:l,rootBoundary:u,strategy:c})),x=d==="floating"?{x:n,y:o,width:s.floating.width,height:s.floating.height}:s.reference,S=await(i.getOffsetParent==null?void 0:i.getOffsetParent(a.floating)),w=await(i.isElement==null?void 0:i.isElement(S))&&await(i.getScale==null?void 0:i.getScale(S))||{x:1,y:1},I=ki(i.convertOffsetParentRelativeRectToViewportRelativeRect?await i.convertOffsetParentRelativeRectToViewportRelativeRect({elements:a,rect:x,offsetParent:S,strategy:c}):x);return{top:(E.top-I.top+g.top)/w.y,bottom:(I.bottom-E.bottom+g.bottom)/w.y,left:(E.left-I.left+g.left)/w.x,right:(I.right-E.right+g.right)/w.x}}async function q9(e,t){let{placement:r,platform:n,elements:o}=e,i=await(n.isRTL==null?void 0:n.isRTL(o.floating)),s=_0(r),a=k0(r),c=Ed(r)==="y",l=Y9.has(s)?-1:1,u=i&&c?-1:1,d=Q0(t,e),{mainAxis:A,crossAxis:f,alignmentAxis:g}=typeof d=="number"?{mainAxis:d,crossAxis:0,alignmentAxis:null}:{mainAxis:d.mainAxis||0,crossAxis:d.crossAxis||0,alignmentAxis:d.alignmentAxis};return a&&typeof g=="number"&&(f=a==="end"?g*-1:g),c?{x:f*u,y:A*l}:{x:A*l,y:f*u}}var W9,A2,Y9,m2,p2=m(()=>{wd();wd();W9=50,A2=async(e,t,r)=>{let{placement:n="bottom",strategy:o="absolute",middleware:i=[],platform:s}=r,a=s.detectOverflow?s:{...s,detectOverflow:d2},c=await(s.isRTL==null?void 0:s.isRTL(t)),l=await s.getElementRects({reference:e,floating:t,strategy:o}),{x:u,y:d}=f2(l,n,c),A=n,f=0,g={};for(let h=0;h<i.length;h++){let y=i[h];if(!y)continue;let{name:E,fn:x}=y,{x:S,y:w,data:I,reset:v}=await x({x:u,y:d,initialPlacement:n,placement:A,strategy:o,middlewareData:g,rects:l,platform:a,elements:{reference:e,floating:t}});u=S??u,d=w??d,g[E]={...g[E],...I},v&&f<W9&&(f++,typeof v=="object"&&(v.placement&&(A=v.placement),v.rects&&(l=v.rects===!0?await s.getElementRects({reference:e,floating:t,strategy:o}):v.rects),{x:u,y:d}=f2(l,A,c)),h=-1)}return{x:u,y:d,placement:A,strategy:o,middlewareData:g}},Y9=new Set(["left","top"]);m2=function(e){return e===void 0&&(e=0),{name:"offset",options:e,async fn(t){var r,n;let{x:o,y:i,placement:s,middlewareData:a}=t,c=await q9(t,e);return s===((r=a.offset)==null?void 0:r.placement)&&(n=a.arrow)!=null&&n.alignmentOffset?{}:{x:o+c.x,y:i+c.y,data:{...c,placement:s}}}}}});function y2(e){let t=kr(e),r=parseFloat(t.width)||0,n=parseFloat(t.height)||0,o=zr(e),i=o?e.offsetWidth:r,s=o?e.offsetHeight:n,a=Al(r)!==i||Al(n)!==s;return a&&(r=i,n=s),{width:r,height:n,$:a}}function x2(e){return _t(e)?e:e.contextElement}function xa(e){let t=x2(e);if(!zr(t))return Bn(1);let r=t.getBoundingClientRect(),{width:n,height:o,$:i}=y2(t),s=(i?Al(r.width):r.width)/n,a=(i?Al(r.height):r.height)/o;return(!s||!Number.isFinite(s))&&(s=1),(!a||!Number.isFinite(a))&&(a=1),{x:s,y:a}}function C2(e){let t=Qt(e);return!fl()||!t.visualViewport?z9:{x:t.visualViewport.offsetLeft,y:t.visualViewport.offsetTop}}function J9(e,t,r){return t===void 0&&(t=!1),!!r&&t&&r===Qt(e)}function gl(e,t,r,n){t===void 0&&(t=!1),r===void 0&&(r=!1);let o=e.getBoundingClientRect(),i=x2(e),s=Bn(1);t&&(n?_t(n)&&(s=xa(n)):s=xa(e));let a=J9(i,r,n)?C2(i):Bn(0),c=(o.left+a.x)/s.x,l=(o.top+a.y)/s.y,u=o.width/s.x,d=o.height/s.y;if(i&&n){let A=Qt(i),f=_t(n)?Qt(n):n,g=A,h=xd(g);for(;h&&f!==g;){let y=xa(h),E=h.getBoundingClientRect(),x=kr(h),S=E.left+(h.clientLeft+parseFloat(x.paddingLeft))*y.x,w=E.top+(h.clientTop+parseFloat(x.paddingTop))*y.y;c*=y.x,l*=y.y,u*=y.x,d*=y.y,c+=S,l+=w,g=Qt(h),h=xd(g)}}return ki({width:u,height:d,x:c,y:l})}function Sd(e,t){let r=dl(e).scrollLeft;return t?t.left+r:gl(ro(e)).left+r}function b2(e,t){let r=e.getBoundingClientRect(),n=r.left+t.scrollLeft-Sd(e,r),o=r.top+t.scrollTop;return{x:n,y:o}}function K9(e){let{elements:t,rect:r,offsetParent:n,strategy:o}=e,i=o==="fixed",s=ro(n),a=t?ul(t.floating):!1;if(n===s||a&&i)return r;let c={scrollLeft:0,scrollTop:0},l=Bn(1),u=Bn(0),d=zr(n);if((d||!i)&&((Po(n)!=="body"||ll(s))&&(c=dl(n)),d)){let f=gl(n);l=xa(n),u.x=f.x+n.clientLeft,u.y=f.y+n.clientTop}let A=s&&!d&&!i?b2(s,c):Bn(0);return{width:r.width*l.x,height:r.height*l.y,x:r.x*l.x-c.scrollLeft*l.x+u.x+A.x,y:r.y*l.y-c.scrollTop*l.y+u.y+A.y}}function X9(e){return e.getClientRects?Array.from(e.getClientRects()):[]}function Z9(e){let t=dl(e),r=e.ownerDocument.body,n=_i(e.scrollWidth,e.clientWidth,r.scrollWidth,r.clientWidth),o=_i(e.scrollHeight,e.clientHeight,r.scrollHeight,r.clientHeight),i=-t.scrollLeft+Sd(e),s=-t.scrollTop;return kr(r).direction==="rtl"&&(i+=_i(e.clientWidth,r.clientWidth)-n),{width:n,height:o,x:i,y:s}}function tH(e,t,r){r===void 0&&(r="viewport");let n=r==="layoutViewport",o=Qt(e),i=ro(e),s=o.visualViewport,a=i.clientWidth,c=i.clientHeight,l=0,u=0;if(s){let A=!fl()||t==="fixed";n?A||(l=-s.offsetLeft,u=-s.offsetTop):(a=s.width,c=s.height,A&&(l=s.offsetLeft,u=s.offsetTop))}if(Sd(i)<=0){let A=i.ownerDocument,f=A.body,g=getComputedStyle(f),h=A.compatMode==="CSS1Compat"&&parseFloat(g.marginLeft)+parseFloat(g.marginRight)||0,y=Math.abs(i.clientWidth-f.clientWidth-h),E=getComputedStyle(i).scrollbarGutter==="stable both-edges"?y/2:y;E<=eH&&(a-=E)}return{width:a,height:c,x:l,y:u}}function rH(e,t){let r=gl(e,!0,t==="fixed"),n=r.top+e.clientTop,o=r.left+e.clientLeft,i=xa(e),s=e.clientWidth*i.x,a=e.clientHeight*i.y,c=o*i.x,l=n*i.y;return{width:s,height:a,x:c,y:l}}function g2(e,t,r){let n;if(t==="viewport"||t==="layoutViewport")n=tH(e,r,t);else if(t==="document")n=Z9(ro(e));else if(_t(t))n=rH(t,r);else{let o=C2(e);n={x:t.x-o.x,y:t.y-o.y,width:t.width,height:t.height}}return ki(n)}function nH(e,t){let r=t.get(e);if(r)return r;let n=ya(e,[],!1).filter(a=>_t(a)&&Po(a)!=="body"),o=null,i=kr(e).position==="fixed",s=i?to(e):e;for(;_t(s)&&!Qi(s);){let a=kr(s),c=yd(s),l=o?o.position:i?"fixed":"";!c&&(l==="fixed"||l==="absolute"&&a.position==="static")?n=n.filter(d=>d!==s):o=a,s=to(s)}return t.set(e,n),n}function oH(e){let{element:t,boundary:r,rootBoundary:n,strategy:o}=e,s=[...r==="clippingAncestors"?ul(t)?[]:nH(t,this._c):[].concat(r),n],a=g2(t,s[0],o),c=a.top,l=a.right,u=a.bottom,d=a.left;for(let A=1;A<s.length;A++){let f=g2(t,s[A],o);c=_i(f.top,c),l=bd(f.right,l),u=bd(f.bottom,u),d=_i(f.left,d)}return{width:l-d,height:u-c,x:d,y:c}}function iH(e){let{width:t,height:r}=y2(e);return{width:t,height:r}}function sH(e,t,r){let n=zr(t),o=ro(t),i=r==="fixed",s=gl(e,!0,i,t),a={scrollLeft:0,scrollTop:0},c=Bn(0);if((n||!i)&&((Po(t)!=="body"||ll(o))&&(a=dl(t)),n)){let A=gl(t,!0,i,t);c.x=A.x+t.clientLeft,c.y=A.y+t.clientTop}!n&&o&&(c.x=Sd(o));let l=o&&!n&&!i?b2(o,a):Bn(0),u=s.left+a.scrollLeft-c.x-l.x,d=s.top+a.scrollTop-c.y-l.y;return{x:u,y:d,width:s.width,height:s.height}}function D0(e){return kr(e).position==="static"}function h2(e,t){if(!zr(e)||kr(e).position==="fixed")return null;if(t)return t(e);let r=e.offsetParent;return ro(e)===r&&(r=r.ownerDocument.body),r}function E2(e,t){let r=Qt(e);if(ul(e))return r;if(!zr(e)){let o=to(e);for(;o&&!Qi(o);){if(_t(o)&&!D0(o))return o;o=to(o)}return r}let n=h2(e,t);for(;n&&ZR(n)&&D0(n);)n=h2(n,t);return n&&Qi(n)&&D0(n)&&!yd(n)?r:n||e2(e)||r}function cH(e){return kr(e).direction==="rtl"}var z9,eH,aH,w2,I2,N0,S2=m(()=>{p2();wd();Cd();z9=Bn(0);eH=25;aH=async function(e){let t=this.getOffsetParent||E2,r=this.getDimensions,n=await r(e.floating);return{reference:sH(e.reference,await t(e.floating),e.strategy),floating:{x:0,y:0,width:n.width,height:n.height}}};w2={convertOffsetParentRelativeRectToViewportRelativeRect:K9,getDocumentElement:ro,getClippingRect:oH,getOffsetParent:E2,getElementRects:aH,getClientRects:X9,getDimensions:iH,getScale:xa,isElement:_t,isRTL:cH},I2=m2,N0=(e,t,r)=>{let n=new Map,o=r??{},i={...w2,...o.platform,_c:n};return A2(e,t,{...o,platform:i})}});function Bd(e,t){if(e===t)return!0;if(typeof e!=typeof t)return!1;if(typeof e=="function"&&e.toString()===t.toString())return!0;let r,n,o;if(e&&t&&typeof e=="object"){if(Array.isArray(e)){if(r=e.length,r!==t.length)return!1;for(n=r;n--!==0;)if(!Bd(e[n],t[n]))return!1;return!0}if(o=Object.keys(e),r=o.length,r!==Object.keys(t).length)return!1;for(n=r;n--!==0;)if(!{}.hasOwnProperty.call(t,o[n]))return!1;for(n=r;n--!==0;){let i=o[n];if(!(i==="_owner"&&e.$$typeof)&&!Bd(e[i],t[i]))return!1}return!0}return e!==e&&t!==t}function M2(e){return typeof window>"u"?1:(e.ownerDocument.defaultView||window).devicePixelRatio||1}function v2(e,t){let r=M2(e);return Math.round(t*r)/r}function L0(e){let t=rt.useRef(e);return vd(()=>{t.current=e}),t}function R2(e){e===void 0&&(e={});let{placement:t="bottom",strategy:r="absolute",middleware:n=[],platform:o,elements:{reference:i,floating:s}={},transform:a=!0,whileElementsMounted:c,open:l}=e,[u,d]=rt.useState({x:0,y:0,strategy:r,placement:t,middlewareData:{},isPositioned:!1}),[A,f]=rt.useState(n);Bd(A,n)||f(n);let[g,h]=rt.useState(null),[y,E]=rt.useState(null),x=rt.useCallback(te=>{te!==v.current&&(v.current=te,h(te))},[]),S=rt.useCallback(te=>{te!==B.current&&(B.current=te,E(te))},[]),w=i||g,I=s||y,v=rt.useRef(null),B=rt.useRef(null),R=rt.useRef(u),D=c!=null,L=L0(c),F=L0(o),C=L0(l),M=rt.useCallback(()=>{if(!v.current||!B.current)return;let te={placement:t,strategy:r,middleware:A};F.current&&(te.platform=F.current),N0(v.current,B.current,te).then(Gr=>{let it={...Gr,isPositioned:C.current!==!1};k.current&&!Bd(R.current,it)&&(R.current=it,T2.flushSync(()=>{d(it)}))})},[A,t,r,F,C]);vd(()=>{l===!1&&R.current.isPositioned&&(R.current.isPositioned=!1,d(te=>({...te,isPositioned:!1})))},[l]);let k=rt.useRef(!1);vd(()=>(k.current=!0,()=>{k.current=!1}),[]),vd(()=>{if(w&&(v.current=w),I&&(B.current=I),w&&I){if(L.current)return L.current(w,I,M);M()}},[w,I,M,L,D]);let G=rt.useMemo(()=>({reference:v,floating:B,setReference:x,setFloating:S}),[x,S]),j=rt.useMemo(()=>({reference:w,floating:I}),[w,I]),oe=rt.useMemo(()=>{let te={position:r,left:0,top:0};if(!j.floating)return te;let Gr=v2(j.floating,u.x),it=v2(j.floating,u.y);return a?{...te,transform:"translate("+Gr+"px, "+it+"px)",...M2(j.floating)>=1.5&&{willChange:"transform"}}:{position:r,left:Gr,top:it}},[r,a,j.floating,u.x,u.y]);return rt.useMemo(()=>({...u,update:M,refs:G,elements:j,floatingStyles:oe}),[u,M,G,j,oe])}var rt,B2,T2,lH,uH,vd,Td,P0=m(()=>{S2();rt=p(Q(),1),B2=p(Q(),1),T2=p(Vf(),1),lH=typeof document<"u",uH=function(){},vd=lH?B2.useLayoutEffect:uH;Td=(e,t)=>{let r=I2(e);return{name:r.name,fn:r.fn,options:[e,t]}}});function CH(){let[e,t]=z.useState(()=>k2?D2():void 0);return pl(()=>{e==null&&t(D2())},[]),z.useEffect(()=>{k2=!0},[]),e}function wH(){let e=new Map;return{emit(t,r){var n;(n=e.get(t))==null||n.forEach(o=>o(r))},on(t,r){e.has(t)||e.set(t,new Set),e.get(t).add(r)},off(t,r){var n;(n=e.get(t))==null||n.delete(r)}}}function TH(e,t){let r=null,n=null,o=!1;return{contextElement:e||void 0,getBoundingClientRect(){var i;let s=e?.getBoundingClientRect()||{width:0,height:0,x:0,y:0},a=t.axis==="x"||t.axis==="both",c=t.axis==="y"||t.axis==="both",l=["mouseenter","mousemove"].includes(((i=t.dataRef.current.openEvent)==null?void 0:i.type)||"")&&t.pointerType!=="touch",u=s.width,d=s.height,A=s.x,f=s.y;return r==null&&t.x&&a&&(r=s.x-t.x),n==null&&t.y&&c&&(n=s.y-t.y),A-=r||0,f-=n||0,u=0,d=0,!o||l?(u=t.axis==="y"?s.width:0,d=t.axis==="x"?s.height:0,A=a&&t.x!=null?t.x:A,f=c&&t.y!=null?t.y:f):o&&!l&&(d=t.axis==="x"?s.height:d,u=t.axis==="y"?s.width:u),o=!0,{width:u,height:d,x:A,y:f,top:f,right:A+u,bottom:f+d,left:A}}}}function N2(e){return e!=null&&e.clientX!=null}function P2(e,t){t===void 0&&(t={});let{open:r,dataRef:n,elements:{floating:o,domReference:i},refs:s}=e,{enabled:a=!0,axis:c="both",x:l=null,y:u=null}=t,d=z.useRef(!1),A=z.useRef(null),[f,g]=z.useState(),[h,y]=z.useState([]),E=Id((v,B)=>{d.current||n.current.openEvent&&!N2(n.current.openEvent)||s.setPositionReference(TH(i,{x:v,y:B,axis:c,dataRef:n,pointerType:f}))}),x=Id(v=>{l!=null||u!=null||(r?A.current||y([]):E(v.clientX,v.clientY))}),S=l2(f)?o:r,w=z.useCallback(()=>{if(!S||!a||l!=null||u!=null)return;let v=Qt(o);function B(R){let D=c2(R);a2(o,D)?(v.removeEventListener("mousemove",B),A.current=null):E(R.clientX,R.clientY)}if(!n.current.openEvent||N2(n.current.openEvent)){v.addEventListener("mousemove",B);let R=()=>{v.removeEventListener("mousemove",B),A.current=null};return A.current=R,R}s.setPositionReference(i)},[S,a,l,u,o,n,s,i,E]);z.useEffect(()=>w(),[w,h]),z.useEffect(()=>{a&&!o&&(d.current=!1)},[a,o]),z.useEffect(()=>{!a&&r&&(d.current=!0)},[a,r]),pl(()=>{a&&(l!=null||u!=null)&&(d.current=!1,E(l,u))},[a,l,u,E]);let I=z.useMemo(()=>{function v(B){let{pointerType:R}=B;g(R)}return{onPointerDown:v,onPointerEnter:v,onMouseMove:x,onMouseEnter:x}},[x]);return z.useMemo(()=>a?{reference:I}:{},[a,I])}function MH(e){let{open:t=!1,onOpenChange:r,elements:n}=e,o=EH(),i=z.useRef({}),[s]=z.useState(()=>wH()),a=vH()!=null,[c,l]=z.useState(n.reference),u=Id((f,g,h)=>{i.current.openEvent=f?g:void 0,s.emit("openchange",{open:f,event:g,reason:h,nested:a}),r?.(f,g,h)}),d=z.useMemo(()=>({setPositionReference:l}),[]),A=z.useMemo(()=>({reference:c||n.reference||null,floating:n.floating||null,domReference:n.reference}),[c,n.reference,n.floating]);return z.useMemo(()=>({dataRef:i,open:t,onOpenChange:u,elements:A,events:s,floatingId:o,refs:d}),[t,u,A,s,o,d])}function F2(e){var t,r;let{elements:n,...o}=e===void 0?{}:e,{nodeId:i}=o,s=MH({...o,elements:{reference:(t=n?.reference)!=null?t:null,floating:(r=n?.floating)!=null?r:null}}),a=o.rootContext||s,c=a.elements,[l,u]=z.useState(null),[d,A]=z.useState(null),g=c?.domReference||l,h=z.useRef(null),y=BH();pl(()=>{g&&(h.current=g)},[g]);let E=R2({...o,elements:{...c,...d&&{reference:d}}}),x=z.useCallback(B=>{let R=_t(B)?{getBoundingClientRect:()=>B.getBoundingClientRect(),getClientRects:()=>B.getClientRects(),contextElement:B}:B;A(R),E.refs.setReference(R)},[E.refs]),S=z.useCallback(B=>{(_t(B)||B===null)&&(h.current=B,u(B)),(_t(E.refs.reference.current)||E.refs.reference.current===null||B!==null&&!_t(B))&&E.refs.setReference(B)},[E.refs]),w=z.useMemo(()=>({...E.refs,setReference:S,setPositionReference:x,domReference:h}),[E.refs,S,x]),I=z.useMemo(()=>({...E.elements,domReference:g}),[E.elements,g]),v=z.useMemo(()=>({...E,...a,refs:w,elements:I,nodeId:i}),[E,w,I,i,a]);return pl(()=>{a.dataRef.current.floatingContext=v;let B=y?.nodesRef.current.find(R=>R.id===i);B&&(B.context=v)}),z.useMemo(()=>({...E,context:v,refs:w,elements:I}),[E,w,I,v])}function F0(e,t,r){let n=new Map,o=r==="item",i=e;if(o&&e){let{[Q2]:s,[_2]:a,...c}=e;i=c}return{...r==="floating"&&{tabIndex:-1,[fH]:""},...i,...t.map(s=>{let a=s?s[r]:null;return typeof a=="function"?e?a(e):null:a}).concat(e).reduce((s,a)=>(a&&Object.entries(a).forEach(c=>{let[l,u]=c;if(!(o&&[Q2,_2].includes(l)))if(l.indexOf("on")===0){if(n.has(l)||n.set(l,[]),typeof u=="function"){var d;(d=n.get(l))==null||d.push(u),s[l]=function(){for(var A,f=arguments.length,g=new Array(f),h=0;h<f;h++)g[h]=arguments[h];return(A=n.get(l))==null?void 0:A.map(y=>y(...g)).find(y=>y!==void 0)}}}else s[l]=u}),s),{})}}function O2(e){e===void 0&&(e=[]);let t=e.map(a=>a?.reference),r=e.map(a=>a?.floating),n=e.map(a=>a?.item),o=z.useCallback(a=>F0(a,e,"reference"),t),i=z.useCallback(a=>F0(a,e,"floating"),r),s=z.useCallback(a=>F0(a,e,"item"),n);return z.useMemo(()=>({getReferenceProps:o,getFloatingProps:i,getItemProps:s}),[o,i,s])}var z,O0,L2,fH,Q2,_2,dH,AH,mH,pH,gH,hH,Vle,yH,k2,xH,D2,bH,EH,IH,SH,vH,BH,G2=m(()=>{z=p(Q(),1);u2();O0=p(O(),1);Cd();L2=p(Vf(),1);P0();P0();fH="data-floating-ui-focusable",Q2="active",_2="selected",dH="ArrowLeft",AH="ArrowRight",mH="ArrowUp",pH="ArrowDown",gH=[dH,AH],hH=[mH,pH],Vle=[...gH,...hH],yH={...z},k2=!1,xH=0,D2=()=>"floating-ui-"+Math.random().toString(36).slice(2,6)+xH++;bH=yH.useId,EH=bH||CH;IH=z.createContext(null),SH=z.createContext(null),vH=()=>{var e;return((e=z.useContext(IH))==null?void 0:e.id)||null},BH=()=>z.useContext(SH)});function RH(e){return Math.round(e*1e5)/1e5}function U0({clientPoint:e,children:t,placement:r="right"}){let o=(0,Ca.useTheme)().components?.MuiPopper,{classes:i}=QH(),{refs:s,floatingStyles:a,context:c}=F2({placement:r,strategy:"fixed",middleware:[Td(5)]}),l=P2(c,e),{getFloatingProps:u}=O2([l]);return(0,G0.jsx)(Ca.Portal,{container:o?.defaultProps?.container,children:(0,G0.jsx)("div",{className:i.tooltip,ref:s.setFloating,style:{...a,zIndex:1e5,visibility:a.transform==="translate(0px, 0px)"?"hidden":void 0,pointerEvents:"none"},...u(),children:t})})}var G0,Ca,QH,U2=m(()=>{G0=p(O(),1);G2();Ca=p(U(),1);Ve();QH=Z()(e=>({tooltip:{position:"absolute",pointerEvents:"none",backgroundColor:(0,Ca.alpha)(e.palette.grey[700],.9),borderRadius:e.shape.borderRadius,color:e.palette.common.white,fontFamily:e.typography.fontFamily,padding:"4px 8px",fontSize:e.typography.fontSize,lineHeight:`${RH(14/10)}em`,maxWidth:300,wordWrap:"break-word"}}))});var H2=m(()=>{});var H0=m(()=>{KR();e0();XR();H2()});function Fo({value:e}){let{classes:t}=_H(),r=/^https?:\/\//.exec(`${e}`);return(0,Md.jsx)("div",{className:t.fieldValue,children:(0,V2.isValidElement)(e)?e:r?(0,Md.jsx)(j2.Link,{href:`${e}`,children:`${e}`}):(0,Md.jsx)(Mo,{html:_r(e)?JSON.stringify(e):String(e)})})}var Md,V2,j2,_H,Rd=m(()=>{Md=p(O(),1),V2=p(Q(),1),j2=p(U(),1);H0();So();Ve();_H=Z()(e=>({fieldValue:{wordBreak:"break-word",maxHeight:300,fontSize:12,padding:e.spacing(.5),overflow:"auto"}}))});function Tn({description:e,name:t,width:r,prefix:n=[]}){let{classes:o}=kH(),i=[...n,t].join(".");return e?(0,Qd.jsx)($2.Tooltip,{title:e,placement:"left",children:(0,Qd.jsx)("div",{className:xf(o.fieldDescription,o.fieldName),children:i})}):(0,Qd.jsx)("div",{className:o.fieldName,style:{width:r},children:i})}var Qd,$2,kH,hl=m(()=>{Qd=p(O(),1),$2=p(U(),1);Ve();kH=Z()(e=>({fieldDescription:{"&:hover":{background:e.palette.mode==="dark"?"#e65100":"yellow"}},fieldName:{wordBreak:"break-all",minWidth:90,borderBottom:"1px solid #0003",fontSize:12,background:e.palette.action.disabledBackground,marginRight:e.spacing(1),padding:e.spacing(.5)}}))});function j0({name:e,value:t,description:r,formatter:n,prefix:o=[]}){let{classes:i}=DH(),[s,a]=(0,W2.useState)(!1),c=t.length>V0,l=c&&!s?t.slice(0,V0):t;return t.length===1?_r(t[0])?(0,$t.jsx)(Mn,{formatter:n,attributes:t[0],prefix:[...o,e]}):(0,$t.jsxs)("div",{className:i.field,children:[(0,$t.jsx)(Tn,{prefix:o,description:r,name:e}),(0,$t.jsx)(Fo,{value:n?n(t[0],e):t[0]})]}):t.every(u=>_r(u))?(0,$t.jsx)($t.Fragment,{children:t.map((u,d)=>(0,$t.jsx)(Mn,{formatter:n,attributes:u,prefix:[...o,`${e}-${d}`]},`${JSON.stringify(u)}-${d}`))}):(0,$t.jsxs)("div",{className:i.field,children:[(0,$t.jsx)(Tn,{prefix:o,description:r,name:e}),l.map((u,d)=>(0,$t.jsx)("div",{className:i.fieldSubvalue,children:(0,$t.jsx)(Fo,{value:n?n(u,e):u})},`${JSON.stringify(u)}-${d}`)),c?(0,$t.jsx)("button",{type:"button",onClick:()=>{a(u=>!u)},children:s?"Show less":`Showing ${V0} of ${t.length}. Show all...`}):null]})}var $t,W2,V0,DH,Y2=m(()=>{$t=p(O(),1),W2=p(Q(),1);_d();Rd();hl();So();Ve();V0=100,DH=Z()(e=>({field:{display:"flex",flexWrap:"wrap"},fieldSubvalue:{wordBreak:"break-word",maxHeight:300,padding:e.spacing(.5),border:`1px solid ${e.palette.action.selected}`,boxSizing:"border-box",overflow:"auto"}}))});var z2=K((due,q2)=>{q2.exports=JBrowseExports["@mui/x-data-grid"]});function $0({children:e,style:t}){let{classes:r}=NH();return(0,J2.jsx)("div",{className:r.flexContainer,style:t,children:e})}var J2,NH,K2=m(()=>{J2=p(O(),1);Ve();NH=Z()({flexContainer:{display:"flex",flexDirection:"column"}})});function W0({value:e,prefix:t,name:r}){let{classes:n}=LH(),[o,i]=(0,X2.useState)(!1),s=Object.keys(e[0]).sort(),a=new Set(s),c=Object.entries(e).map(([d,A])=>{let{id:f,...g}=A;return{id:d,identifier:f,...g}});for(let d of e)for(let A of Object.keys(d))a.add(A);let l;a.has("id")?(a.delete("id"),l=["identifier",...a]):l=[...a];let u=l.map(d=>yT(c.map(A=>A[d])));return a.size<s.length+5?(0,Jr.jsxs)("div",{className:n.margin,children:[(0,Jr.jsx)(Tn,{prefix:t,name:r}),(0,Jr.jsx)(ba.FormControlLabel,{control:(0,Jr.jsx)(ba.Checkbox,{checked:o,onChange:d=>{i(d.target.checked)}}),label:(0,Jr.jsx)(ba.Typography,{variant:"body2",children:"Show options"})}),(0,Jr.jsx)($0,{children:(0,Jr.jsx)(Z2.DataGrid,{disableRowSelectionOnClick:!0,rows:c,rowHeight:20,columnHeaderHeight:35,hideFooter:c.length<25,showToolbar:o,columns:l.map((d,A)=>({field:d,width:u[A],renderCell:({value:f})=>(0,Jr.jsx)("div",{className:n.cell,children:(0,Jr.jsx)(Mo,{html:$h(f||"")})})}))})})]}):null}var Jr,X2,ba,Z2,LH,eQ=m(()=>{Jr=p(O(),1),X2=p(Q(),1),ba=p(U(),1),Z2=p(z2(),1);hl();K2();H0();So();Ve();LH=Z()(e=>({margin:{marginBottom:e.spacing(4)},cell:{whiteSpace:"nowrap",overflow:"hidden",textOverflow:"ellipsis"}}))});function Y0({name:e,value:t,description:r,prefix:n,width:o,formatter:i}){let{classes:s}=PH();return t!=null?(0,yl.jsxs)("div",{className:s.field,children:[(0,yl.jsx)(Tn,{prefix:n,description:r,name:e,width:o}),(0,yl.jsx)(Fo,{value:i?i(t,e):t})]}):null}var yl,PH,tQ=m(()=>{yl=p(O(),1);Rd();hl();Ve();PH=Z()({field:{display:"flex",flexWrap:"wrap"}})});function q0({value:e,prefix:t,name:r}){let{classes:n}=FH(),{uri:o,baseUri:i=""}=e,s;try{s=new URL(o,i).href}catch{s=o}return(0,xl.jsxs)("div",{className:n.field,children:[(0,xl.jsx)(Tn,{prefix:t,name:r}),(0,xl.jsx)(Fo,{value:s})]})}var xl,FH,rQ=m(()=>{xl=p(O(),1);Rd();hl();Ve();FH=Z()({field:{display:"flex",flexWrap:"wrap"}})});function nQ(e,t){return e.map(r=>t.slice(r.start,r.end)).join("")}var oQ=m(()=>{});function iQ(e,t){return Math.ceil(Wh(e.map(r=>Vh([...t,r[0]].join("."),12))))+10}function sQ(e,t={}){let r=t;for(let n of e)_r(r)&&(r=r[n]);return typeof r=="string"?r:_r(r)&&typeof r.Description=="string"?r.Description:void 0}var aQ=m(()=>{So()});function Mn(e){let{attributes:t,omit:r=[],omitSingleLevel:n=[],descriptions:o,formatter:i,hideUris:s,prefix:a=[]}=e,c=new Set([...r,...GH,...n]),{__jbrowsefmt:l,...u}=t,d=Object.entries({...u,...l}).filter(([f,g])=>g!=null&&!c.has(f)),A=iQ(d,a);return(0,no.jsx)(no.Fragment,{children:d.map(([f,g])=>{let h=sQ([...a,f],o);if(Array.isArray(g))return g.length>1&&g.every(y=>_r(y))?(0,no.jsx)(W0,{name:f,prefix:a,value:g},f):(0,no.jsx)(j0,{name:f,value:g,formatter:i,description:h,prefix:a},f);if(_r(g)){let{omitSingleLevel:y,...E}=e;return jf(g)?s?null:(0,no.jsx)(q0,{name:f,prefix:a,value:g},f):(0,no.jsx)(Mn,{...E,formatter:i,attributes:g,descriptions:o,prefix:[...a,f]},f)}else return(0,no.jsx)(Y0,{name:f,formatter:i,value:g,description:h,prefix:a,width:Math.min(A,OH)},f)})})}var no,OH,GH,_d=m(()=>{no=p(O(),1);Y2();eQ();tQ();rQ();aQ();So();OH=170,GH=["__jbrowsefmt","length","position","subfeatures","uniqueId","exonFrames","parentId","thickStart","thickEnd","_lineHash"]});var cQ,lQ,uQ=m(()=>{"use client";sr();cQ=p(O(),1),lQ=(0,Me.createSvgIcon)((0,cQ.jsx)("path",{d:"M16.59 8.59 12 13.17 7.41 8.59 6 10l6 6 6-6z"}),"ExpandMore")});function Ni({children:e,title:t,defaultExpanded:r=!0}){let{classes:n}=UH();return(0,Di.jsxs)(Oo.Accordion,{defaultExpanded:r,children:[(0,Di.jsx)(Oo.AccordionSummary,{expandIcon:(0,Di.jsx)(lQ,{className:n.icon}),children:(0,Di.jsx)(Oo.Typography,{variant:"button",children:t})}),(0,Di.jsx)(Oo.AccordionDetails,{className:n.expansionPanelDetails,children:e})]})}var Di,Oo,UH,z0=m(()=>{Di=p(O(),1);uQ();Oo=p(U(),1);Ve();UH=Z()(e=>({expansionPanelDetails:{display:"block",padding:e.spacing(1)},icon:{color:e.palette.tertiary.contrastText||"#fff"}}))});function Li({checked:e,label:t,disabled:r,onChange:n}){return kd.default.createElement("div",null,kd.default.createElement(Dd.FormControlLabel,{control:kd.default.createElement(Dd.Checkbox,{disabled:r,checked:e,onChange:()=>{n()}}),label:t}))}var kd,Dd,J0=m(()=>{kd=p(Q(),1),Dd=p(U(),1)});function Cl({str:e}){let{classes:t}=HH(),[r,n]=(0,Kr.useState)(!1),[o,i]=(0,Kr.useState)(!1),[s,a]=(0,Kr.useState)(!1),c=u=>u.replaceAll("-","").replaceAll(".",""),l=e.map(([u,d])=>[u,o?d:c(d)]).filter(([,u])=>s||!!u).map(([u,d])=>`>${u}
-${d}`).join(`
-`);return Kr.default.createElement(Kr.default.Fragment,null,Kr.default.createElement(Nd.Button,{color:"primary",variant:"contained",onClick:()=>{Pc(l),n(!0),setTimeout(()=>{n(!1)},500)}},r?"Copied!":"Copy to clipboard"),Kr.default.createElement(Li,{label:"Show gaps",checked:o,onChange:()=>{i(!o)}}),Kr.default.createElement(Li,{label:"Show empty",checked:s,onChange:()=>{a(!s)}}),Kr.default.createElement(Nd.TextField,{variant:"outlined",multiline:!0,className:t.dialogContent,minRows:5,maxRows:10,fullWidth:!0,value:l,slotProps:{input:{readOnly:!0,className:t.textAreaFont}}}))}var Kr,Nd,HH,K0=m(()=>{Kr=p(Q(),1);Ve();Nd=p(U(),1);xg();J0();HH=Z()({textAreaFont:{fontFamily:"Courier New",wordWrap:"break-word"},dialogContent:{background:"lightgrey",margin:4,minWidth:"80em"}})});var mQ={};Bt(mQ,{default:()=>jH});var Ea,fQ,dQ,AQ,VH,jH,pQ=m(()=>{Ea=p(Q(),1);_d();z0();fQ=p(Ze(),1),dQ=p(U(),1),AQ=p(W(),1);K0();VH=(0,AQ.observer)(function({model:e,onClose:t}){let{header:r}=e;return Ea.default.createElement(fQ.Dialog,{onClose:()=>{t()},open:!0,title:"Metadata",maxWidth:"xl"},Ea.default.createElement(dQ.DialogContent,null,Ea.default.createElement(Mn,{attributes:r}),Ea.default.createElement(Ni,{title:"sequence"},Ea.default.createElement(Cl,{str:e.rows}))))}),jH=VH});var hQ={};Bt(hQ,{default:()=>gQ});function gQ({model:e,onClose:t}){let[r,n]=(0,Pe.useState)(!0),[o,i]=(0,Pe.useState)(!0),[s,a]=(0,Pe.useState)("viewport"),[c,l]=(0,Pe.useState)(),u=(0,_e.useTheme)(),{totalWidth:d,totalHeight:A,treeAreaWidth:f,turnedOnTracks:g,totalTrackAreaHeight:h}=e,y=g.length>0,E=d+f,x=A+(o?h:0),S=s==="entire"&&(E>1e4||x>1e4);return Pe.default.createElement(Ld.Dialog,{onClose:()=>{t()},open:!0,title:"Export SVG"},Pe.default.createElement(_e.DialogContent,null,c?Pe.default.createElement(Ld.ErrorMessage,{error:c}):null,Pe.default.createElement(_e.Typography,null,"Settings:"),Pe.default.createElement(Li,{label:"Include minimap?",disabled:s==="entire",checked:r,onChange:()=>{n(!r)}}),y?Pe.default.createElement(Li,{label:"Include tracks?",checked:o,onChange:()=>{i(!o)}}):null,Pe.default.createElement("div",null,Pe.default.createElement(_e.FormControl,null,Pe.default.createElement(_e.FormLabel,null,"Export type"),Pe.default.createElement(_e.RadioGroup,{value:s,onChange:w=>{let{value:I}=w.target;(I==="entire"||I==="viewport")&&a(I)}},Pe.default.createElement(_e.FormControlLabel,{value:"entire",control:Pe.default.createElement(_e.Radio,null),label:"Entire MSA"}),Pe.default.createElement(_e.FormControlLabel,{value:"viewport",control:Pe.default.createElement(_e.Radio,null),label:"Current viewport only"})))),S?Pe.default.createElement(_e.Alert,{severity:"warning",style:{marginTop:8}},"The entire MSA is very large (",Math.round(E),"x",Math.round(x)," pixels). Export may be slow or fail."):null),Pe.default.createElement(_e.DialogActions,null,Pe.default.createElement(_e.Button,{variant:"contained",color:"primary",onClick:()=>{e.exportSVG({theme:u,includeMinimap:s==="entire"?!1:r,includeTracks:y&&o,exportType:s}).then(()=>{t()}).catch(w=>{console.error(w),l(w)})}},"Submit"),Pe.default.createElement(_e.Button,{variant:"contained",color:"secondary",onClick:()=>{t()}},"Cancel")))}var Pe,Ld,_e,yQ=m(()=>{Pe=p(Q(),1),Ld=p(Ze(),1),_e=p(U(),1);J0()});var wa,xQ,$H,WH,YH,CQ,bQ=m(()=>{wa=p(Q(),1);Aa();NM();a0();OM();UM();xQ=p(W(),1);PR();$H=(0,wa.lazy)(()=>Promise.resolve().then(()=>(pQ(),mQ))),WH=(0,wa.lazy)(()=>Promise.resolve().then(()=>(yQ(),hQ))),YH=(0,xQ.observer)(({model:e})=>wa.default.createElement(vn,{"data-testid":"file_menu",tooltip:"File",menuItems:[{label:"Return to import form",icon:cd,onClick:()=>{e.reset()}},{label:"Metadata",icon:DM,onClick:()=>{e.queueDialog(t=>[$H,{model:e,onClose:t}])}},{label:"Domain settings",type:"subMenu",subMenu:LR({model:e})},{label:"Export SVG",icon:GM,onClick:()=>{e.queueDialog(t=>[WH,{onClose:t,model:e}])}}],anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"}},wa.default.createElement(FM,null))),CQ=YH});var Pd,Fd,EQ,qH,wQ,IQ=m(()=>{Pd=p(Q(),1),Fd=p(U(),1),EQ=p(W(),1),qH=(0,EQ.observer)(function({model:t}){let{hideGaps:r,allowedGappyness:n}=t;return r?Pd.default.createElement("div",{style:{display:"flex",alignItems:"center",gap:8}},Pd.default.createElement(Fd.Typography,{style:{whiteSpace:"nowrap"}},"Hide columns w/ >",n,"% gaps"),Pd.default.createElement(Fd.Slider,{"data-testid":"gappyness_slider",style:{width:100},min:1,max:100,value:n,onChange:(o,i)=>{t.setAllowedGappyness(i)}})):null}),wQ=qH});var Od,SQ,vQ,zH,JH,BQ,TQ=m(()=>{Od=p(Q(),1);Ve();SQ=p(U(),1),vQ=p(W(),1),zH=Z()({container:{display:"flex",overflow:"hidden",margin:"auto",marginLeft:10},nameFirst:{overflow:"hidden",textOverflow:"ellipsis",whiteSpace:"nowrap",minWidth:0},nameRest:{whiteSpace:"nowrap",flexShrink:0}}),JH=(0,vQ.observer)(function({model:e}){let{mouseOverRowName:t,mouseCol:r}=e,{classes:n}=zH();if(!t||r===void 0)return null;let o=Math.floor(t.length/2),i=e.visibleColToSeqPosOneBased(t,r),s=e.visibleColToRowLetter(t,r);return Od.default.createElement(SQ.Typography,{component:"div",className:n.container,title:t},Od.default.createElement("span",{className:n.nameFirst},t.slice(0,o)),Od.default.createElement("span",{className:n.nameRest},t.slice(o),":",i," (",s,")"))}),BQ=JH});var bl,MQ,Gd,RQ,KH,XH,QQ,_Q=m(()=>{bl=p(Q(),1),MQ=p(Ze(),1);Ve();Gd=p(U(),1),RQ=p(W(),1),KH=Z()({margin:{margin:"auto",marginLeft:10}}),XH=(0,RQ.observer)(({model:e})=>{let{status:t}=e,{classes:r}=KH();return t?bl.default.createElement(Gd.Typography,{className:r.margin},bl.default.createElement(MQ.LoadingEllipses,{message:t.msg,component:"span"})," ",t.url?bl.default.createElement("a",{href:t.url,target:"_blank",rel:"noreferrer"},"(status)"):null," ",t.onCancel?bl.default.createElement(Gd.Button,{size:"small",onClick:()=>t.onCancel?.()},"Cancel"):null):null}),QQ=XH});var kQ,DQ,NQ=m(()=>{"use client";Ie();kQ=p(O(),1),DQ=Y((0,kQ.jsx)("path",{d:"M3 17v2h6v-2zM3 5v2h10V5zm10 16v-2h8v-2h-8v-2h-2v6zM7 9v2H3v2h4v2h2V9zm14 4v-2H11v2zm-6-4h2V7h4V5h-4V3h-2z"}),"Tune")});function LQ(e){let{drawMsaLetters:t,hideGaps:r,bgColor:n,showColumnStats:o}=e;return[{label:"Show column statistics on hover",type:"checkbox",checked:o,onClick:()=>{e.setShowColumnStats(!o)}},{label:"Draw letters",type:"checkbox",checked:t,onClick:()=>{e.setDrawMsaLetters(!t)}},{label:"Color letters instead of background of tiles",type:"checkbox",checked:!n,onClick:()=>{e.setBgColor(!n)}},{label:"Enable hiding gappy columns?",type:"checkbox",checked:r,onClick:()=>{e.setHideGaps(!r)}}]}function PQ(e){let{drawTree:t,showBranchLen:r,labelsAlignRight:n,drawNodeBubbles:o,drawLabels:i}=e;return[{label:"Show branch length",type:"checkbox",checked:r,onClick:()=>{e.setShowBranchLen(!r)}},{label:"Show tree",type:"checkbox",checked:t,onClick:()=>{e.setDrawTree(!t)}},{label:"Draw clickable bubbles on tree branches",type:"checkbox",checked:o,onClick:()=>{e.setDrawNodeBubbles(!o)}},{label:"Tree labels align right",type:"checkbox",checked:n,onClick:()=>{e.setLabelsAlignRight(!n)}},{label:"Draw labels",type:"checkbox",checked:i,onClick:()=>{e.setDrawLabels(!i)}}]}var X0=m(()=>{});var Z0,FQ,ZH,OQ,GQ=m(()=>{Z0=p(Q(),1);Aa();NQ();FQ=p(W(),1);X0();ZH=(0,FQ.observer)(function({model:e}){return Z0.default.createElement(vn,{"data-testid":"msa_settings_menu",tooltip:"Alignment settings",closeAfterItemClick:!1,anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"},menuItems:LQ(e)},Z0.default.createElement(DQ,null))}),OQ=ZH});var ey,Ud,UQ,eV,HQ,VQ=m(()=>{ey=p(Q(),1),Ud=p(U(),1),UQ=p(W(),1),eV=(0,UQ.observer)(function({model:e}){let{currentAlignment:t,alignmentNames:r}=e,n=new Map;return r.length>0?ey.default.createElement(Ud.TextField,{select:!0,variant:"outlined",value:t,size:"small",onChange:o=>{e.setCurrentAlignment(+o.target.value),e.setScrollX(0),e.setScrollY(0)}},r.map((o,i)=>{let s=n.get(o)??0;return n.set(o,s+1),ey.default.createElement(Ud.MenuItem,{key:s===0?o:`${o}\0${s}`,value:i},o)})):null}),HQ=eV});var jQ,$Q,WQ=m(()=>{"use client";Ie();jQ=p(O(),1),$Q=Y((0,jQ.jsx)("path",{d:"M22 11V3h-7v3H9V3H2v8h7V8h2v10h4v3h7v-8h-7v3h-2V8h2v3z"}),"AccountTree")});var ty,YQ,tV,qQ,zQ=m(()=>{ty=p(Q(),1);Aa();WQ();YQ=p(W(),1);X0();tV=(0,YQ.observer)(function({model:e}){let{rows:t}=e;return ty.default.createElement(vn,{"data-testid":"tree_settings_menu",tooltip:"Tree settings",closeAfterItemClick:!1,anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"},menuItems:[...PQ(e),...t.length>=2?[{label:"Advanced",type:"subMenu",subMenu:[{label:"Calculate neighbor joining tree (BLOSUM62)",onClick:()=>{try{e.calculateNeighborJoiningTreeFromMSA()}catch(r){console.error("Failed to calculate NJ tree:",r),e.setError(r)}}}]}]:[]]},ty.default.createElement($Q,null))}),qQ=tV});var JQ,KQ,XQ=m(()=>{"use client";Ie();JQ=p(O(),1),KQ=Y((0,JQ.jsx)("path",{d:"M13 1.07V9h7c0-4.08-3.05-7.44-7-7.93M4 15c0 4.42 3.58 8 8 8s8-3.58 8-8v-4H4zm7-13.93C7.05 1.56 4 4.92 4 9h7z"}),"Mouse")});var ry,ZQ,e_=m(()=>{"use client";Ie();ry=p(O(),1),ZQ=Y([(0,ry.jsx)("path",{d:"M15.5 14h-.79l-.28-.27C15.41 12.59 16 11.11 16 9.5 16 5.91 13.09 3 9.5 3S3 5.91 3 9.5 5.91 16 9.5 16c1.61 0 3.09-.59 4.23-1.57l.27.28v.79l5 4.99L20.49 19zm-6 0C7.01 14 5 11.99 5 9.5S7.01 5 9.5 5 14 7.01 14 9.5 11.99 14 9.5 14"},"0"),(0,ry.jsx)("path",{d:"M12 10h-2v2H9v-2H7V9h2V7h1v2h2z"},"1")],"ZoomIn")});var t_,r_,n_=m(()=>{"use client";Ie();t_=p(O(),1),r_=Y((0,t_.jsx)("path",{d:"M15.5 14h-.79l-.28-.27C15.41 12.59 16 11.11 16 9.5 16 5.91 13.09 3 9.5 3S3 5.91 3 9.5 5.91 16 9.5 16c1.61 0 3.09-.59 4.23-1.57l.27.28v.79l5 4.99L20.49 19zm-6 0C7.01 14 5 11.99 5 9.5S7.01 5 9.5 5 14 7.01 14 9.5 11.99 14 9.5 14M7 9h5v1H7z"}),"ZoomOut")});var Xr,Go,o_,rV,i_,s_=m(()=>{Xr=p(Q(),1);XQ();e_();n_();Go=p(U(),1),o_=p(W(),1),rV=(0,o_.observer)(function({model:t}){return Xr.default.createElement(Xr.default.Fragment,null,Xr.default.createElement(Go.Tooltip,{title:"Zoom in"},Xr.default.createElement(Go.IconButton,{"aria-label":"Zoom in",onClick:()=>{t.zoomIn()}},Xr.default.createElement(ZQ,null))),Xr.default.createElement(Go.Tooltip,{title:"Zoom out"},Xr.default.createElement(Go.IconButton,{"aria-label":"Zoom out",onClick:()=>{t.zoomOut()}},Xr.default.createElement(r_,null))),Xr.default.createElement(Go.ToggleButton,{value:"scrollZoom",selected:t.scrollZoom,"aria-label":"Toggle scroll-to-zoom",title:"Toggle scroll-to-zoom (zoom on plain mouse wheel; ctrl+wheel always zooms)",size:"small",sx:{border:"none"},onChange:()=>{t.setScrollZoom(!t.scrollZoom)}},Xr.default.createElement(KQ,null)))}),i_=rV});var a_,c_,l_=m(()=>{"use client";Ie();a_=p(O(),1),c_=Y((0,a_.jsx)("path",{d:"M12 8c1.1 0 2-.9 2-2s-.9-2-2-2-2 .9-2 2 .9 2 2 2m0 2c-1.1 0-2 .9-2 2s.9 2 2 2 2-.9 2-2-.9-2-2-2m0 6c-1.1 0-2 .9-2 2s.9 2 2 2 2-.9 2-2-.9-2-2-2"}),"MoreVert")});var u_,f_,d_=m(()=>{"use client";Ie();u_=p(O(),1),f_=Y((0,u_.jsx)("path",{d:"M12 5V2L8 6l4 4V7c3.31 0 6 2.69 6 6 0 2.97-2.17 5.43-5 5.91v2.02c3.95-.49 7-3.85 7-7.93 0-4.42-3.58-8-8-8m-6 8c0-1.65.67-3.15 1.76-4.24L6.34 7.34C4.9 8.79 4 10.79 4 13c0 4.08 3.05 7.44 7 7.93v-2.02c-2.83-.48-5-2.94-5-5.91"}),"RestartAlt")});var ny,A_,nV,m_,p_=m(()=>{ny=p(Q(),1);Aa();l_();d_();A_=p(W(),1),nV=(0,A_.observer)(function({model:e}){return ny.default.createElement(vn,{tooltip:"Fit / zoom options",menuItems:[{label:"Fit both vertically/horizontally",onClick:()=>{e.fit()}},{label:"Fit vertically",onClick:()=>{e.fitVertically()}},{label:"Fit horizontally",onClick:()=>{e.fitHorizontally()}},{label:"Reset zoom to default",icon:f_,onClick:()=>{e.resetZoom()}}]},ny.default.createElement(c_,null))}),m_=nV});var g_,h_=m(()=>{g_="5.7.2"});var C_={};Bt(C_,{default:()=>x_});function x_({onClose:e}){return at.default.createElement(y_.Dialog,{open:!0,title:"About",onClose:()=>{e()}},at.default.createElement(Wt.DialogContent,null,at.default.createElement(Wt.Typography,null,"MSAView ",g_," (",at.default.createElement(Wt.Link,{href:"https://github.com/gmod/react-msaview"},"Github"),")"),at.default.createElement("ul",null,at.default.createElement("li",null,at.default.createElement(Wt.Typography,null,"We use some color schemes from the"," ",at.default.createElement(Wt.Link,{href:"https://github.com/biotite-dev/biotite"},"biotite")," ","project, and their license is reproduced"," ",at.default.createElement(Wt.Link,{href:"https://github.com/biotite-dev/biotite/blob/master/LICENSE.rst"},"here"))),at.default.createElement("li",null,at.default.createElement(Wt.Typography,null,"See this page for some information on jalview colorings"," ",at.default.createElement(Wt.Link,{href:"https://www.jalview.org/help/html/colourSchemes/"},"here"))),at.default.createElement("li",null,at.default.createElement(Wt.Typography,null,"See this page for some info on the clustal, cinema, maeditor, and lesk color schemes"," ",at.default.createElement(Wt.Link,{href:"http://www.bioinformatics.nl/~berndb/aacolour.html"},"here"))),at.default.createElement("li",null,at.default.createElement(Wt.Typography,null,"See this paper about the flower color scheme"," ",at.default.createElement(Wt.Link,{href:"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245768/"},"here"))))))}var at,y_,Wt,b_=m(()=>{at=p(Q(),1),y_=p(Ze(),1),Wt=p(U(),1);h_()});function sV(){return je.default.createElement("div",{style:{flex:1}})}var je,Hd,E_,oV,iV,w_,I_=m(()=>{je=p(Q(),1);vS();MS();Hd=p(U(),1),E_=p(W(),1);_M();bQ();IQ();TQ();_Q();GQ();VQ();zQ();s_();p_();oV=(0,je.lazy)(()=>Promise.resolve().then(()=>(b_(),C_))),iV=(0,E_.observer)(function({model:e}){let[t,{height:r}]=bg();return(0,je.useEffect)(()=>{e.setHeaderHeight(r??0)},[e,r]),je.default.createElement("div",{ref:t,style:{display:"flex"}},je.default.createElement(CQ,{model:e}),je.default.createElement(QM,{model:e}),je.default.createElement(qQ,{model:e}),je.default.createElement(OQ,{model:e}),je.default.createElement(i_,{model:e}),je.default.createElement(m_,{model:e}),je.default.createElement(wQ,{model:e}),je.default.createElement("div",{style:{paddingLeft:20,margin:"auto"}},je.default.createElement(HQ,{model:e})),je.default.createElement(BQ,{model:e}),je.default.createElement(sV,null),je.default.createElement(QQ,{model:e}),je.default.createElement(Hd.Tooltip,{title:"About"},je.default.createElement(Hd.IconButton,{"aria-label":"About",onClick:()=>{e.queueDialog(n=>[oV,{onClose:n}])}},je.default.createElement(TS,null))))});w_=iV});var Rn,S_,aV,v_,B_=m(()=>{Rn=p(Q(),1),S_=p(W(),1);hf();Fp();aV=(0,S_.observer)(function({model:e}){let[t,r]=(0,Rn.useState)(!1),{minimapHeight:n}=e,{unit:o,s:i,w:s,polygonHeight:a,polygonPoints:c}=ef(e),l="rgba(66, 119, 127, 0.3)",{startDrag:u}=bo("x",(0,Rn.useCallback)((d,A)=>{e.setScrollX(A-d/o)},[e,o]));return Rn.default.createElement("div",{style:{position:"relative",height:n,width:"100%"}},Rn.default.createElement("div",{style:{height:12,boxSizing:"border-box",border:"1px solid #555"}}),Rn.default.createElement("div",{style:{position:"absolute",top:0,left:Math.max(0,i),background:t?"rgba(66,119,127,0.6)":l,cursor:"pointer",height:12,width:s,zIndex:100},onMouseOver:()=>{r(!0)},onMouseOut:()=>{r(!1)},onMouseDown:d=>{u(d,e.scrollX)}}),Rn.default.createElement("svg",{height:a,style:{width:"100%"}},Rn.default.createElement("polygon",{fill:l,points:c})))}),v_=aV});var T_,M_,R_=m(()=>{"use client";Ie();T_=p(O(),1),M_=Y((0,T_.jsx)("path",{d:"m12 8-6 6 1.41 1.41L12 10.83l4.59 4.58L18 14z"}),"ExpandLess")});var Q_,Vd,oy=m(()=>{"use client";Ie();Q_=p(O(),1),Vd=Y((0,Q_.jsx)("path",{d:"M16.59 8.59 12 13.17 7.41 8.59 6 10l6 6 6-6z"}),"ExpandMore")});var Zr,Ia,__,cV,k_,D_=m(()=>{Zr=p(Q(),1);R_();oy();Ia=p(U(),1),__=p(W(),1),cV=(0,__.observer)(function({model:e}){let[t,r]=(0,Zr.useState)(!0),{actuallyShowDomains:n,visibleDomainTypes:o,fillPalette:i}=e,s=t?M_:Vd;return n&&o.length>0?Zr.default.createElement(Ia.Paper,{elevation:3,style:{position:"absolute",top:4,right:4,zIndex:100,maxWidth:260,maxHeight:"60%",display:"flex",flexDirection:"column",opacity:.95}},Zr.default.createElement("div",{style:{display:"flex",alignItems:"center",justifyContent:"flex-end",padding:"2px 4px 2px 8px"}},Zr.default.createElement(Ia.IconButton,{size:"small",onClick:()=>{r(!t)}},Zr.default.createElement(s,{fontSize:"small"}))),t?Zr.default.createElement("div",{style:{overflow:"auto",padding:"0 8px 6px"}},o.map(({accession:a,name:c})=>Zr.default.createElement("div",{key:a,style:{display:"flex",alignItems:"center",gap:6},title:a},Zr.default.createElement("div",{style:{width:12,height:12,flexShrink:0,background:i[a]}}),Zr.default.createElement(Ia.Typography,{variant:"caption",noWrap:!0},c)))):null):null}),k_=cV});function iy(){return jd.default.createElement("div",{style:{position:"absolute",left:"50%",top:"50%"}},jd.default.createElement($d.CircularProgress,null),jd.default.createElement($d.Typography,null,"Loading..."))}var jd,$d,N_=m(()=>{jd=p(Q(),1),$d=p(U(),1)});function Dr(e,t){let r=(0,Wd.useRef)(null);return(0,Wd.useEffect)(()=>{let n=r.current?.getContext("2d");return n?(0,L_.autorun)(()=>{e(n)}):void 0},t),r}var Wd,L_,Pi=m(()=>{Wd=p(Q(),1),L_=p(Ps(),1)});function Yd(e){let t=(0,F_.useTheme)(),r=(0,P_.useMemo)(()=>Bc(e,t),[e,t]);return{theme:t,contrastScheme:r}}var P_,F_,sy=m(()=>{P_=p(Q(),1),F_=p(U(),1);Co()});var mr,O_,ay,lV,G_,U_=m(()=>{mr=p(Q(),1),O_=p(W(),1),ay=e=>`${Math.round(e*100)}%`,lV=(0,O_.observer)(function({model:e}){let t=e.mouseOverColumnStats;if(!t)return null;let{col:r,total:n,conservation:o,propertyConservation:i,consensusLetter:s,consensusFraction:a,gapFraction:c,distribution:l}=t,u=l.slice(0,6);return mr.default.createElement("div",null,mr.default.createElement("b",null,"Column ",r+1)," (",n," seqs)",mr.default.createElement("br",null),"Consensus: ",s||"-"," (",ay(a),")",mr.default.createElement("br",null),"Conservation: ",o.toFixed(2),i===void 0?null:mr.default.createElement(mr.default.Fragment,null,mr.default.createElement("br",null),"Property conservation: ",i.toFixed(2)),mr.default.createElement("br",null),"Gaps: ",ay(c),u.length>0?mr.default.createElement(mr.default.Fragment,null,mr.default.createElement("br",null),u.map(([d,A])=>mr.default.createElement("span",{key:d,style:{marginRight:8}},d," ",ay(A/n)))):null)}),G_=lV});function uV({event:e,el:t,offsetX:r,offsetY:n,colWidth:o,rowHeight:i}){let{left:s,top:a}=t.getBoundingClientRect();return{col:Math.floor((e.clientX-s+r)/o),row:Math.floor((e.clientY-a+n)/i)}}function V_({model:e,offsetX:t,offsetY:r}){let[n,o]=(0,H_.useState)();function i(u,d){let{colWidth:A,rowHeight:f}=e;return uV({event:u,el:d,offsetX:t,offsetY:r,colWidth:A,rowHeight:f})}function s({col:u,row:d}){return u>=0&&u<e.numColumns&&d>=0&&d<e.numRows}function a(u,d){let A=i(u,d),f=s(A);e.setMousePos(f?A.col:void 0,f?A.row:void 0);let g=!!e.hoveredInsertion||e.mouseOverDomains.length>0||e.showColumnStats&&!!e.mouseOverColumnStats;o(g?{x:u.clientX,y:u.clientY}:void 0)}function c(u,d){let A=i(u,d),{col:f,row:g}=A,{mouseClickCol:h,mouseClickRow:y}=e,E=f===h&&g===y,x=s(A)&&!E;e.setMouseClickPos(x?f:void 0,x?g:void 0)}function l(){e.setMousePos(),o(void 0)}return{tooltipPoint:n,onMouseMove:a,onClick:c,onMouseLeave:l}}var H_,j_=m(()=>{H_=p(Q(),1)});var Yt,$_,fV,W_,Y_=m(()=>{Yt=p(Q(),1);U2();$_=p(W(),1);Pi();sy();U_();Up();Zp();j_();fV=(0,$_.observer)(function({model:e,offsetX:t,offsetY:r}){let{scrollY:n,scrollX:o,colorScheme:i,blockSize:s,highResScaleFactor:a}=e,{theme:c,contrastScheme:l}=Yd(i),{tooltipPoint:u,onMouseMove:d,onClick:A,onMouseLeave:f}=V_({model:e,offsetX:t,offsetY:r}),g=Dr(x=>{let{blockSize:S,highResScaleFactor:w,actuallyShowDomains:I}=e;x.resetTransform(),x.clearRect(0,0,S*w,S*w),I&&sf({ctx:x,offsetX:t,offsetY:r,model:e}),ff({ctx:x,theme:c,offsetX:t,offsetY:r,contrastScheme:l,model:e})},[e,t,r,c,l]),{hoveredInsertion:h,mouseOverDomains:y,showColumnStats:E}=e;return Yt.default.createElement(Yt.default.Fragment,null,Yt.default.createElement("canvas",{ref:g,onMouseMove:x=>{g.current&&d(x,g.current)},onClick:x=>{g.current&&A(x,g.current)},onMouseLeave:()=>{f()},width:s*a,height:s*a,style:{position:"absolute",top:n+r,left:o+t,width:s,height:s}}),u?Yt.default.createElement(U0,{clientPoint:{x:u.x,y:u.y+15}},h?Yt.default.createElement(Yt.default.Fragment,null,"Insertion (",h.letters.length,e.sequenceType==="amino"?"aa":"bp","):"," ",h.letters.length>20?`${h.letters.slice(0,20)}...`:h.letters):Yt.default.createElement(Yt.default.Fragment,null,y.map(x=>Yt.default.createElement("div",{key:`${x.accession}-${x.start}-${x.end}`},Yt.default.createElement("b",null,x.name)," (",x.accession,") ",x.start,"-",x.end,x.description?Yt.default.createElement(Yt.default.Fragment,null,Yt.default.createElement("br",null),x.description):null)),E?Yt.default.createElement(G_,{model:e}):null)):null)}),W_=fV});var Qn,q_,dV,z_,J_=m(()=>{Qn=p(Q(),1),q_=p(W(),1);Cf();N_();Y_();dV=(0,q_.observer)(function({model:e}){let{MSA:t,verticalScrollbarWidth:r,msaFilehandle:n,height:o,msaAreaWidth:i,blocks2d:s,scrollZoom:a}=e,c=(0,Qn.useRef)(null),l=(0,Qn.useCallback)(g=>{e.doScrollX(g)},[e]),u=(0,Qn.useCallback)(g=>{e.doScrollY(g)},[e]),d=(0,Qn.useCallback)((g,h,y)=>{e.zoomToPos(g,h,y)},[e]),{onMouseDown:A,onMouseUp:f}=$s({ref:c,onScrollX:l,onScrollY:u,onZoom:d,scrollZoom:a});return Qn.default.createElement("div",{ref:c,"data-testid":"msa_canvas",onMouseDown:A,onMouseUp:f,onMouseLeave:g=>{g.preventDefault()},style:{position:"relative",height:o,width:i-r,overflow:"hidden"}},!t&&!n?null:t?s.map(([g,h])=>Qn.default.createElement(W_,{key:`${g}_${h}`,model:e,offsetX:g,offsetY:h})):Qn.default.createElement(iy,null))}),z_=dV});var qd,K_,X_,cy=m(()=>{qd="rgba(0,128,255,0.3)",K_="rgba(255,165,0,0.2)",X_="rgba(255,165,0,0.15)"});function tk({ctx:e,model:t}){let{mouseCol:r,colWidth:n,msaAreaWidth:o,verticalScrollbarWidth:i,height:s,rowHeight:a,scrollX:c,scrollY:l,mouseRow:u,mouseClickRow:d,mouseClickCol:A,highResScaleFactor:f,referenceRowIndex:g,hoveredRowIndices:h,highlightedColumnRuns:y}=t,E=o-i;if(e.resetTransform(),e.clearRect(0,0,E*f,s*f),e.scale(f,f),g!==void 0&&(e.fillStyle=qd,e.fillRect(0,g*a+l,E,a)),h.length>0){e.fillStyle=X_;for(let x of h)e.fillRect(0,x*a+l,E,a)}if(y.length>0){e.lineWidth=2;for(let{start:x,end:S}of y){let w=x*n+c,I=(S-x+1)*n;e.fillStyle=AV,e.fillRect(w,0,I,s),e.strokeStyle=mV,e.strokeRect(w,0,I,s)}}r!==void 0&&(e.fillStyle=Z_,e.fillRect(r*n+c,0,n,s)),u!==void 0&&(e.fillStyle=Z_,e.fillRect(0,u*a+l,E,a)),A!==void 0&&(e.fillStyle=ek,e.fillRect(A*n+c,0,n,s)),d!==void 0&&(e.fillStyle=ek,e.fillRect(0,d*a+l,E,a))}var Z_,ek,AV,mV,rk=m(()=>{cy();Z_="rgba(0,0,0,0.15)",ek="rgba(128,128,0,0.2)",AV="rgba(255,140,0,0.28)",mV="rgba(210,90,0,0.95)"});var nk,ok,ik,pV,sk,ak=m(()=>{nk=p(Q(),1),ok=p(Kt(),1),ik=p(W(),1);Pi();rk();pV=(0,ik.observer)(function({model:e}){let{height:t,msaAreaWidth:r,verticalScrollbarWidth:n,highResScaleFactor:o}=e,i=r-n,s=Dr(a=>{(0,ok.isAlive)(e)&&tk({ctx:a,model:e})},[e]);return nk.default.createElement("canvas",{ref:s,id:"mouseover",width:i*o,height:t*o,style:{position:"absolute",top:0,left:0,width:i,height:t,zIndex:1e3,pointerEvents:"none"}})}),sk=pV});var El,ck,gV,lk,uk=m(()=>{El=p(Q(),1),ck=p(W(),1);D_();J_();ak();gV=(0,ck.observer)(function({model:e}){return El.default.createElement("div",{style:{position:"relative"}},El.default.createElement(z_,{model:e}),El.default.createElement(sk,{model:e}),El.default.createElement(k_,{model:e}))}),lk=gV});var wl,Sa,fk,hV,dk,Ak=m(()=>{wl=p(Q(),1),Sa=p(U(),1),fk=p(W(),1),hV=(0,fk.observer)(function({node:e,model:t,onClose:r}){return wl.default.createElement(Sa.Menu,{anchorReference:"anchorPosition",anchorPosition:{left:e.x,top:e.y},transitionDuration:0,keepMounted:!0,open:!!e,onClose:r},wl.default.createElement(Sa.MenuItem,{dense:!0,disabled:!0},e.name),wl.default.createElement(Sa.MenuItem,{dense:!0,onClick:()=>{t.toggleCollapsed(e.id),r()}},t.collapsed.includes(e.id)?"Expand this node":"Collapse this node"),wl.default.createElement(Sa.MenuItem,{dense:!0,onClick:()=>{t.showOnly===e.id?t.setShowOnly(void 0):t.setShowOnly(e.id),r()}},t.showOnly===e.id?"Disable show only this node":"Show only this node"))}),dk=hV});var hk={};Bt(hk,{default:()=>xV});var _n,mk,pk,gk,yV,xV,yk=m(()=>{_n=p(Q(),1);_d();z0();mk=p(Ze(),1),pk=p(U(),1),gk=p(W(),1);K0();yV=(0,gk.observer)(function({info:e,model:t,nodeName:r,onClose:n}){let{treeMetadata:o,rows:i}=t,s=o[r],a=i.find(c=>c[0]===r);return _n.default.createElement(mk.Dialog,{onClose:()=>{n()},open:!0,title:"Tree node info",maxWidth:"xl"},_n.default.createElement(pk.DialogContent,null,_n.default.createElement(Ni,{title:"Attributes"},_n.default.createElement(Mn,{attributes:{nodeName:r,...e}})),_n.default.createElement(Ni,{title:"Sequence"},a?_n.default.createElement(Cl,{str:[a]}):_n.default.createElement("div",null,"Sequence not found")),s?_n.default.createElement(Ni,{title:"Extra metadata"},_n.default.createElement(Mn,{attributes:s})):null))}),xV=yV});var oo,Uo,xk,CV,bV,Ck,bk=m(()=>{oo=p(Q(),1),Uo=p(U(),1),xk=p(W(),1),CV=(0,oo.lazy)(()=>Promise.resolve().then(()=>(yk(),hk))),bV=(0,xk.observer)(function({node:e,onClose:t,model:r}){let{collapsed:n}=r,{name:o,id:i}=e,s=n.includes(i);return oo.default.createElement(Uo.Menu,{anchorReference:"anchorPosition",anchorPosition:{top:e.y,left:e.x},transitionDuration:0,keepMounted:!0,open:!!e,onClose:t},oo.default.createElement(Uo.MenuItem,{dense:!0,disabled:!0},o),oo.default.createElement(Uo.MenuItem,{dense:!0,onClick:()=>{r.queueDialog(a=>[CV,{info:r.getRowData(o),model:r,nodeName:o,onClose:a}]),t()}},"More info..."),oo.default.createElement(Uo.MenuItem,{dense:!0,onClick:()=>{r.toggleCollapsed(i),t()}},s?"Expand subtree":"Collapse subtree"),oo.default.createElement(Uo.MenuItem,{dense:!0,onClick:()=>{r.drawRelativeTo(e.name),t()}},"Indicate differences from this row"),r.relativeTo?oo.default.createElement(Uo.MenuItem,{dense:!0,onClick:()=>{r.drawRelativeTo(void 0),t()}},"Clear reference row"):null)}),Ck=bV});var Il,Ek=m(()=>{Il=class{constructor(t=1/0,r=Float64Array,n=Uint32Array){let o=t!==1/0;this.ids=o?new n(t):[],this.values=o?new r(t):[],this.capacity=t,this.length=0}clear(){this.length=0}push(t,r){if(this.length===this.capacity)throw new RangeError("Queue is at capacity.");let n=this.length++;for(;n>0;){let o=n-1>>1,i=this.values[o];if(r>=i)break;this.ids[n]=this.ids[o],this.values[n]=i,n=o}this.ids[n]=t,this.values[n]=r}pop(){if(this.length===0)return;let t=this.ids,r=this.values,n=t[0],o=--this.length;if(o>0){let i=t[o],s=r[o],a=0,c=o>>1;for(;a<c;){let l=(a<<1)+1,u=l+1,d=l+(+(u<o)&+(r[u]<r[l]));if(r[d]>=s)break;t[a]=t[d],r[a]=r[d],a=d}t[a]=i,r[a]=s}return n}peek(){return this.length>0?this.ids[0]:void 0}peekValue(){return this.length>0?this.values[0]:void 0}shrink(){Array.isArray(this.ids)&&(this.ids.length=this.length),Array.isArray(this.values)&&(this.values.length=this.length)}}});function EV(e,t){let r=0,n=t.length-1;for(;r<n;){let o=r+n>>1;t[o]>e?n=o:r=o+1}return t[r]}function wV(e,t,r,n,o,i){let s=[n,o];for(;s.length;){let a=s.pop()||0,c=s.pop()||0;if(a-c<=i&&Math.floor(c/i)>=Math.floor(a/i))continue;let l=e[c],u=e[c+a>>1],d=e[a],A=l>u!=l>d?l:u<l!=u<d?u:d,f=c-1,g=a+1;for(;;){do f++;while(e[f]<A);do g--;while(e[g]>A);if(f>=g)break;IV(e,t,r,f,g)}s.push(c,g,g+1,a)}}function IV(e,t,r,n,o){let i=e[n];e[n]=e[o],e[o]=i;let s=4*n,a=4*o,c=t[s],l=t[s+1],u=t[s+2],d=t[s+3];t[s]=t[a],t[s+1]=t[a+1],t[s+2]=t[a+2],t[s+3]=t[a+3],t[a]=c,t[a+1]=l,t[a+2]=u,t[a+3]=d;let A=r[n];r[n]=r[o],r[o]=A}function SV(e,t){let r=e^t,n=65535^r,o=65535^(e|t),i=e&(t^65535),s=r|n>>1,a=r>>1^r,c=o^(o>>1^n&i>>1),l=i^(r&o>>1^i>>1);return r=s&s>>2^a&a>>2,n=s&a>>2^a&(s^a)>>2,o=c^(s&c>>2^a&l>>2),i=l^(a&c>>2^(s^a)&l>>2),s=r&r>>4^n&n>>4,a=r&n>>4^n&(r^n)>>4,c=o^(r&o>>4^n&i>>4),l=i^(n&o>>4^(r^n)&i>>4),o=c^(s&c>>8^a&l>>8),i=l^(a&c>>8^(s^a)&l>>8),o^=o>>1,i^=i>>1,r=e^t,n=i|65535^(r|o),r=(r|r<<8)&16711935,r=(r|r<<4)&252645135,r=(r|r<<2)&858993459,r=(r|r<<1)&1431655765,n=(n|n<<8)&16711935,n=(n|n<<4)&252645135,n=(n|n<<2)&858993459,n=(n|n<<1)&1431655765,((n<<1|r)>>>0)-2147483648}var wk,ly,Sl,Ik=m(()=>{Ek();wk=[Int8Array,Uint8Array,Uint8ClampedArray,Int16Array,Uint16Array,Int32Array,Uint32Array,Float32Array,Float64Array],ly=3,Sl=class e{static from(t,r=0){if(r%8!==0)throw new Error("byteOffset must be 8-byte aligned.");if(!t||t.byteLength===void 0||"buffer"in t)throw new Error("Data must be an instance of ArrayBuffer or SharedArrayBuffer.");let[n,o]=new Uint8Array(t,r+0,2);if(n!==251)throw new Error("Data does not appear to be in a Flatbush format.");let i=o>>4;if(i!==ly)throw new Error(`Got v${i} data when expected v${ly}.`);let s=wk[o&15];if(!s)throw new Error("Unrecognized array type.");let[a]=new Uint16Array(t,r+2,1),[c]=new Uint32Array(t,r+4,1);return new e(c,a,s,void 0,t,r)}constructor(t,r=16,n=Float64Array,o=ArrayBuffer,i,s=0){if(t===void 0)throw new Error("Missing required argument: numItems.");if(isNaN(t)||t<=0)throw new Error(`Unexpected numItems value: ${t}.`);this.numItems=+t,this.nodeSize=Math.min(Math.max(+r,2),65535),this.byteOffset=s;let a=t,c=a;this._levelBounds=[a*4];do a=Math.ceil(a/this.nodeSize),c+=a,this._levelBounds.push(c*4);while(a!==1);this.ArrayType=n,this.IndexArrayType=c<16384?Uint16Array:Uint32Array;let l=wk.indexOf(n),u=c*4*n.BYTES_PER_ELEMENT;if(l<0)throw new Error(`Unexpected typed array class: ${n}.`);let d=n,A=this.IndexArrayType;if(i)this.data=i,this._boxes=new d(i,s+8,c*4),this._indices=new A(i,s+8+u,c),this._pos=c*4,this.minX=this._boxes[this._pos-4],this.minY=this._boxes[this._pos-3],this.maxX=this._boxes[this._pos-2],this.maxY=this._boxes[this._pos-1];else{let f=this.data=new o(8+u+c*this.IndexArrayType.BYTES_PER_ELEMENT);this._boxes=new d(f,8,c*4),this._indices=new A(f,8+u,c),this._pos=0,this.minX=1/0,this.minY=1/0,this.maxX=-1/0,this.maxY=-1/0,new Uint8Array(f,0,2).set([251,(ly<<4)+l]),new Uint16Array(f,2,1)[0]=r,new Uint32Array(f,4,1)[0]=t}this._queue=new Il}add(t,r,n=t,o=r){let i=this._pos,s=i>>2,a=this._boxes;return this._indices[s]=s,a[i]=t,a[i+1]=r,a[i+2]=n,a[i+3]=o,this._pos=i+4,t<this.minX&&(this.minX=t),r<this.minY&&(this.minY=r),n>this.maxX&&(this.maxX=n),o>this.maxY&&(this.maxY=o),s}finish(){if(this._pos>>2!==this.numItems)throw new Error(`Added ${this._pos>>2} items when expected ${this.numItems}.`);let t=this._boxes;if(this.numItems<=this.nodeSize){t[this._pos++]=this.minX,t[this._pos++]=this.minY,t[this._pos++]=this.maxX,t[this._pos++]=this.maxY;return}let{numItems:r,minX:n,minY:o,nodeSize:i,_indices:s,_levelBounds:a}=this,c=this.maxX-n||1,l=this.maxY-o||1,u=new Int32Array(r),d=65535,A=d/c,f=d/l;for(let h=0,y=0;h<r;h++){let E=t[y++],x=t[y++],S=t[y++],w=t[y++],I=A*((E+S)/2-n)|0,v=f*((x+w)/2-o)|0;u[h]=SV(I,v)}wV(u,t,s,0,r-1,i);let g=r*4;for(let h=0,y=0;h<a.length-1;h++){let E=a[h];for(;y<E;){let x=y,S=t[y++],w=t[y++],I=t[y++],v=t[y++];for(let B=1;B<i&&y<E;B++)S=Math.min(S,t[y++]),w=Math.min(w,t[y++]),I=Math.max(I,t[y++]),v=Math.max(v,t[y++]);s[g>>2]=x,t[g++]=S,t[g++]=w,t[g++]=I,t[g++]=v}}this._pos=g}search(t,r,n,o,i){if(this._pos!==this._boxes.length)throw new Error("Data not yet indexed - call index.finish().");let{_boxes:s,_levelBounds:a,_indices:c,nodeSize:l}=this,u=this.numItems*4,d=s.length-4,A=a.length-1,f=[],g=[],h=!1;for(;d!==void 0;){let y=Math.min(d+l*4,a[A]),E=d>=u;if(h)this._collectContained(d,y,A,u,g,i);else for(let x=d;x<y;x+=4){let S=s[x];if(n<S)continue;let w=s[x+1];if(o<w)continue;let I=s[x+2];if(t>I)continue;let v=s[x+3];if(r>v)continue;let B=c[x>>2]|0;if(E){let R=+(t<=S&&r<=w&&n>=I&&o>=v);f.push(B|R,A-1)}else(i===void 0||i(B,S,w,I,v))&&g.push(B)}A=f.pop(),d=f.pop(),d!==void 0&&(h=(d&1)===1,d&=-2)}return g}_collectContained(t,r,n,o,i,s){let a=this._boxes,c=this._indices,l=t;for(let d=n;d>0;d--)l=c[l>>2];let u=Math.min(l+(r-t)*this.nodeSize**n,o);if(s===void 0)for(;l<u;l+=4)i.push(c[l>>2]|0);else for(;l<u;l+=4){let d=c[l>>2]|0;s(d,a[l],a[l+1],a[l+2],a[l+3])&&i.push(d)}}neighbors(t,r,n=1/0,o=1/0,i){if(this._pos!==this._boxes.length)throw new Error("Data not yet indexed - call index.finish().");let{_boxes:s,_levelBounds:a,_indices:c,_queue:l,nodeSize:u}=this,d=this.numItems*4,A=u*4,f=[],g=o*o,h=n===1,y=g;for(l.push(s.length-4<<1,0);l.length;){let E=l.ids[0];if(E&1){if(l.pop(),f.push(E>>1),f.length===n)break;continue}l.pop();let x=E>>1,S=x<d,w=Math.min(x+A,EV(x,a));for(let I=x;I<w;I+=4){let v=s[I],B=s[I+1],R=s[I+2],D=s[I+3],L=Math.max(Math.max(v-t,t-R),0),F=Math.max(Math.max(B-r,r-D),0),C=L*L+F*F;if(C>y)continue;let M=c[I>>2]|0;S?(i===void 0||i(M))&&(l.push(M<<1|1,C),h&&C<y&&(y=C)):l.push(M<<1,C)}}return l.clear(),f}}});var zd,Sk=m(()=>{Ik();zd=class{flatbush=null;entries=[];clear(){this.flatbush=null,this.entries=[]}insert(t){this.entries.push(t)}finish(){if(this.entries.length===0)this.flatbush=null;else{this.flatbush=new Sl(this.entries.length);for(let t of this.entries)this.flatbush.add(t.minX,t.minY,t.maxX,t.maxY);this.flatbush.finish()}}search(t){return this.flatbush?.search(t.minX,t.minY,t.maxX,t.maxY).map(r=>this.entries[r])??[]}}});function vk({model:e,offsetY:t}){let r=(0,Jd.useRef)(null);r.current??=new zd;let n=r.current,[o,i]=(0,Jd.useState)();function s(l){let u=l.nativeEvent.offsetX,d=l.nativeEvent.offsetY+t,A=n.search({minX:u,maxX:u+1,minY:d,maxY:d+1});return A.find(f=>!f.branch)??A[0]}function a(l){let u=s(l);i(u?{...u,clientX:l.clientX,clientY:l.clientY}:void 0),e.setHoveredTreeNode(u?.id),e.setMousePos(void 0,u&&!u.branch?e.rowNamesSet.get(u.name):void 0)}function c(){i(void 0),e.setHoveredTreeNode(void 0),e.setMousePos(void 0,void 0)}return{clickMap:n,hovered:o,hitTest:s,onMouseMove:a,onMouseLeave:c}}var Jd,Bk=m(()=>{Jd=p(Q(),1);Sk()});var en,Tk,Mk,vV,BV,Rk,Qk=m(()=>{en=p(Q(),1);Ve();Tk=p(U(),1),Mk=p(W(),1);Pi();Ak();bk();gf();Bk();vV=Z()(e=>({tooltip:{position:"fixed",pointerEvents:"none",zIndex:1e4,backgroundColor:e.palette.grey[700],color:e.palette.common.white,padding:"4px 8px",borderRadius:4,fontSize:12,whiteSpace:"nowrap",maxWidth:300,overflow:"hidden",textOverflow:"ellipsis"},hover:{position:"absolute",pointerEvents:"none",zIndex:100,background:"rgba(0,0,0,0.1)"}})),BV=(0,Mk.observer)(function({model:e,offsetY:t}){let{classes:r}=vV(),n=(0,Tk.useTheme)(),[o,i]=(0,en.useState)(),[s,a]=(0,en.useState)(),{clickMap:c,hovered:l,hitTest:u,onMouseMove:d,onMouseLeave:A}=vk({model:e,offsetY:t}),{scrollY:f,treeAreaWidth:g,blockSize:h,highResScaleFactor:y}=e,E=g+mf,x=h,S=Dr(I=>{I.resetTransform(),I.clearRect(0,0,E*y,x*y),pf({ctx:I,model:e,offsetY:t,clickMap:c,theme:n})},[e,c,t,n]),w={width:E,height:x,top:f+t,left:0,position:"absolute"};return en.default.createElement(en.default.Fragment,null,o?en.default.createElement(dk,{node:o,model:e,onClose:()=>{i(void 0)}}):null,s?en.default.createElement(Ck,{node:s,model:e,onClose:()=>{a(void 0)}}):null,en.default.createElement("canvas",{ref:S,width:E*y,height:x*y,style:{...w,cursor:l?"pointer":"default"},onMouseMove:I=>{d(I)},onMouseLeave:()=>{A()},onClick:I=>{let v=u(I);if(v){let B={x:I.clientX,y:I.clientY,id:v.id,name:v.name};v.branch?i(B):a(B)}}}),l&&!l.branch?en.default.createElement("div",{className:r.hover,style:{left:l.minX,top:l.minY+f,width:l.maxX-l.minX,height:l.maxY-l.minY}}):null,l?en.default.createElement("div",{className:r.tooltip,style:{left:l.clientX+12,top:l.clientY+12}},l.name):null)}),Rk=BV});var Ho,_k,kk,TV,Dk,Nk=m(()=>{Ho=p(Q(),1),_k=p(Kt(),1),kk=p(W(),1);Pi();Cf();cy();Qk();gf();TV=(0,kk.observer)(function({model:e}){let t=(0,Ho.useRef)(null),{treeWidth:r,height:n,blocksY:o,treeAreaWidth:i}=e,s=(0,Ho.useCallback)(u=>{e.doScrollY(u)},[e]),{onMouseDown:a,onMouseUp:c}=$s({ref:t,onScrollY:s}),l=Dr(u=>{if((0,_k.isAlive)(e)){let{rowHeight:d,treeAreaWidth:A,height:f,scrollY:g,mouseRow:h,referenceRowIndex:y,hoveredRowIndices:E}=e;u.resetTransform(),u.clearRect(0,0,A,f);let x=S=>{u.fillRect(0,S*d+g,A,d)};y!==void 0&&(u.fillStyle=qd,x(y)),u.fillStyle=K_;for(let S of E)x(S);h!==void 0&&h!==y&&!E.includes(h)&&x(h)}},[e]);return Ho.default.createElement("div",{ref:t,onMouseDown:a,onMouseUp:c,onMouseLeave:u=>{u.preventDefault()},style:{height:n,position:"relative",width:r+mf}},o.map(u=>Ho.default.createElement(Rk,{key:u,model:e,offsetY:u})),Ho.default.createElement("canvas",{ref:l,width:i,height:n,style:{position:"absolute",top:0,left:0,width:i,height:n,zIndex:1e3,pointerEvents:"none"}}))}),Dk=TV});var uy,Lk,MV,Pk,Fk=m(()=>{uy=p(Q(),1),Lk=p(W(),1);Nk();MV=(0,Lk.observer)(function({model:e}){let{treeAreaWidth:t}=e;return uy.default.createElement("div",{style:{overflow:"hidden",flexShrink:0,width:t}},uy.default.createElement(Dk,{model:e}))}),Pk=MV});var Ok,Gk,RV,Uk,Hk=m(()=>{Ok=p(Q(),1),Gk=p(W(),1),RV=(0,Gk.observer)(({model:e})=>{let{treeAreaWidth:t}=e;return Ok.default.createElement("div",{style:{flexShrink:0,width:t}})}),Uk=RV});var ue,Fi,QV,_V,kV,DV,NV,LV,Vk,jk=m(()=>{ue=p(Q(),1),Fi=p(W(),1);pg();bS();SS();I_();B_();uk();Fk();Hk();QV=(0,Fi.observer)(function({model:e}){let{showHorizontalScrollbar:t}=e;return ue.default.createElement("div",{style:{display:"flex"}},ue.default.createElement(Uk,{model:e}),t?ue.default.createElement(v_,{model:e}):null)}),_V=(0,Fi.observer)(function({model:e}){let{mouseCol:t,mouseClickCol:r,colWidth:n,scrollX:o,treeAreaWidth:i,resizeHandleWidth:s,totalTrackAreaHeight:a,msaAreaWidth:c,verticalScrollbarWidth:l}=e,u=i+s,d=c-l;return ue.default.createElement("div",{style:{position:"absolute",left:u,top:0,width:d,height:a,overflow:"hidden",pointerEvents:"none"}},t!==void 0?ue.default.createElement("div",{style:{position:"absolute",left:t*n+o,top:0,width:n,height:a,backgroundColor:"rgba(0,0,0,0.15)",zIndex:100}}):null,r!==void 0?ue.default.createElement("div",{style:{position:"absolute",left:r*n+o,top:0,width:n,height:a,backgroundColor:"rgba(128,128,0,0.2)",zIndex:100}}):null)}),kV=(0,Fi.observer)(function({model:e}){let{turnedOnTracks:t}=e;return t.length===0?null:ue.default.createElement("div",{style:{position:"relative"}},ue.default.createElement(_V,{model:e}),t.map(r=>ue.default.createElement(CS,{key:r.model.id,model:e,track:r})))}),DV=(0,Fi.observer)(function({model:e}){let{showVerticalScrollbar:t}=e;return ue.default.createElement("div",{style:{display:"flex"}},ue.default.createElement(Pk,{model:e}),ue.default.createElement(jI,{model:e}),ue.default.createElement(lk,{model:e}),t?ue.default.createElement(IS,{model:e}):null)}),NV=(0,Fi.observer)(function({model:e}){return ue.default.createElement("div",{style:{position:"relative"}},ue.default.createElement(QV,{model:e}),ue.default.createElement(kV,{model:e}),ue.default.createElement(DV,{model:e}))}),LV=(0,Fi.observer)(function({model:e}){let{height:t,viewInitialized:r,DialogComponent:n,DialogProps:o}=e;return ue.default.createElement("div",null,r?ue.default.createElement(ue.default.Fragment,null,ue.default.createElement("div",{style:{height:t,overflow:"hidden"}},ue.default.createElement(w_,{model:e}),ue.default.createElement(NV,{model:e})),ue.default.createElement($I,{model:e}),n?ue.default.createElement(ue.Suspense,{fallback:null},ue.default.createElement(n,{...o})):null):null)}),Vk=LV});var $k,Wk,Yk,qk=m(()=>{$k=`CLUSTAL O(1.2.3) multiple sequence alignment
+`),onProgress:l=>{t.setStatus(l?{...l,onCancel:()=>{a.abort()}}:void 0)},model:t,signal:a.signal})}catch(c){console.error(c),(0,HR.getSession)(t).notifyError(`${c}`,c)}finally{t.setStatus()}})(),e()}},"Send sequences to InterProScan")))}),EH=CH});function WR({model:e}){let{showDomains:t,actuallyShowDomains:r,subFeatureRows:n,noDomains:o}=e;return[{label:"Open domains...",icon:yd,onClick:()=>{e.queueDialog(i=>[wH,{handleClose:i,model:e}])}},{label:"Query InterProScan for domains...",icon:iR,onClick:()=>{e.queueDialog(i=>[IH,{handleClose:i,model:e}])}},{label:`Show domains${o?" (no domains loaded)":""}`,disabled:o,icon:fR,checked:r,type:"checkbox",onClick:()=>{e.setShowDomains(!t)}},{label:`Use sub-row layout${o?" (no domains loaded)":""}`,disabled:o,checked:r?n:!1,icon:cR,type:"checkbox",onClick:()=>{e.setSubFeatureRows(!n)}},{label:`Filter domains${o?" (no domains loaded)":""}`,icon:rR,disabled:o,onClick:()=>{e.queueDialog(i=>[bH,{onClose:i,model:e}])}}]}var vd,bH,wH,IH,YR=m(()=>{vd=p(Q(),1);nR();g0();sR();lR();dR();bH=(0,vd.lazy)(()=>Promise.resolve().then(()=>(pR(),mR))),wH=(0,vd.lazy)(()=>Promise.resolve().then(()=>(bR(),ER))),IH=(0,vd.lazy)(()=>Promise.resolve().then(()=>($R(),jR)))});var SH,k0,qR=m(()=>{SH={50:"#ffebee",100:"#ffcdd2",200:"#ef9a9a",300:"#e57373",400:"#ef5350",500:"#f44336",600:"#e53935",700:"#d32f2f",800:"#c62828",900:"#b71c1c",A100:"#ff8a80",A200:"#ff5252",A400:"#ff1744",A700:"#d50000"},k0=SH});var vH,D0,zR=m(()=>{vH={50:"#e3f2fd",100:"#bbdefb",200:"#90caf9",300:"#64b5f6",400:"#42a5f5",500:"#2196f3",600:"#1e88e5",700:"#1976d2",800:"#1565c0",900:"#0d47a1",A100:"#82b1ff",A200:"#448aff",A400:"#2979ff",A700:"#2962ff"},D0=vH});var BH,N0,JR=m(()=>{BH={50:"#e8f5e9",100:"#c8e6c9",200:"#a5d6a7",300:"#81c784",400:"#66bb6a",500:"#4caf50",600:"#43a047",700:"#388e3c",800:"#2e7d32",900:"#1b5e20",A100:"#b9f6ca",A200:"#69f0ae",A400:"#00e676",A700:"#00c853"},N0=BH});var TH,L0,KR=m(()=>{TH={50:"#fff3e0",100:"#ffe0b2",200:"#ffcc80",300:"#ffb74d",400:"#ffa726",500:"#ff9800",600:"#fb8c00",700:"#f57c00",800:"#ef6c00",900:"#e65100",A100:"#ffd180",A200:"#ffab40",A400:"#ff9100",A700:"#ff6d00"},L0=TH});var MH,ko,XR=m(()=>{MH={50:"#fafafa",100:"#f5f5f5",200:"#eeeeee",300:"#e0e0e0",400:"#bdbdbd",500:"#9e9e9e",600:"#757575",700:"#616161",800:"#424242",900:"#212121",A100:"#f5f5f5",A200:"#eeeeee",A400:"#bdbdbd",A700:"#616161"},ko=MH});var ZR=m(()=>{qR();zR();JR();KR();XR()});var n2=X((Gce,r2)=>{"use strict";var RH=function(t){return QH(t)&&!_H(t)};function QH(e){return!!e&&typeof e=="object"}function _H(e){var t=Object.prototype.toString.call(e);return t==="[object RegExp]"||t==="[object Date]"||NH(e)}var kH=typeof Symbol=="function"&&Symbol.for,DH=kH?Symbol.for("react.element"):60103;function NH(e){return e.$$typeof===DH}function LH(e){return Array.isArray(e)?[]:{}}function fl(e,t){return t.clone!==!1&&t.isMergeableObject(e)?ga(LH(e),e,t):e}function FH(e,t,r){return e.concat(t).map(function(n){return fl(n,r)})}function PH(e,t){if(!t.customMerge)return ga;var r=t.customMerge(e);return typeof r=="function"?r:ga}function OH(e){return Object.getOwnPropertySymbols?Object.getOwnPropertySymbols(e).filter(function(t){return Object.propertyIsEnumerable.call(e,t)}):[]}function e2(e){return Object.keys(e).concat(OH(e))}function t2(e,t){try{return t in e}catch{return!1}}function GH(e,t){return t2(e,t)&&!(Object.hasOwnProperty.call(e,t)&&Object.propertyIsEnumerable.call(e,t))}function UH(e,t,r){var n={};return r.isMergeableObject(e)&&e2(e).forEach(function(o){n[o]=fl(e[o],r)}),e2(t).forEach(function(o){GH(e,o)||(t2(e,o)&&r.isMergeableObject(t[o])?n[o]=PH(o,r)(e[o],t[o],r):n[o]=fl(t[o],r))}),n}function ga(e,t,r){r=r||{},r.arrayMerge=r.arrayMerge||FH,r.isMergeableObject=r.isMergeableObject||RH,r.cloneUnlessOtherwiseSpecified=fl;var n=Array.isArray(t),o=Array.isArray(e),i=n===o;return i?n?r.arrayMerge(e,t,r):UH(e,t,r):fl(t,r)}ga.all=function(t,r){if(!Array.isArray(t))throw new Error("first argument should be an array");return t.reduce(function(n,o){return ga(n,o,r)},{})};var HH=ga;r2.exports=HH});function s2(){return{palette:{...Bd,mode:void 0},components:{MuiLink:{styleOverrides:{root:({theme:e})=>({color:e.palette.tertiary.main})}}}}}function n9(){return{...s2(),name:"Default (from config)"}}function o9(){return{...s2(),name:"Light (stock)"}}function i9(){return{name:"Dark (stock)",palette:{...Bd,mode:"dark"},components:{MuiAppBar:{defaultProps:{enableColorOnDark:!0},styleOverrides:{root:({theme:e})=>e.palette.primary.main}}}}}function s9(){return{name:"Dark (minimal)",palette:{...Bd,mode:"dark",primary:{main:ko[700]},secondary:{main:ko[800]},tertiary:Ge.palette.augmentColor({color:{main:ko[900]}})}}}function a9(){return{name:"Light (minimal)",palette:{...Bd,primary:{main:ko[900]},secondary:{main:ko[800]},tertiary:Ge.palette.augmentColor({color:{main:ko[900]}})}}}var i2,VH,Ge,jH,$H,WH,o2,Hce,YH,qH,zH,JH,KH,XH,ZH,e9,t9,r9,Bd,Vce,a2=m(()=>{i2=p(U(),1);ZR();VH=p(n2(),1),Ge=(0,i2.createTheme)(),jH=Ge.palette.augmentColor({color:{main:"#0D233F"}}),$H=Ge.palette.augmentColor({color:{main:"#721E63"}}),WH=Ge.palette.augmentColor({color:{main:"#135560"}}),o2=Ge.palette.augmentColor({color:{main:"#FFB11D"}}),Hce=Ge.palette.augmentColor({color:{main:"#aaa"}}),YH={A:Ge.palette.augmentColor({color:N0}),C:Ge.palette.augmentColor({color:D0}),G:Ge.palette.augmentColor({color:L0}),T:Ge.palette.augmentColor({color:k0})},qH=[null,Ge.palette.augmentColor({color:{main:"#FF8080"}}),Ge.palette.augmentColor({color:{main:"#80FF80"}}),Ge.palette.augmentColor({color:{main:"#8080FF"}}),Ge.palette.augmentColor({color:{main:"#8080FF"}}),Ge.palette.augmentColor({color:{main:"#80FF80"}}),Ge.palette.augmentColor({color:{main:"#FF8080"}})],zH=[null,Ge.palette.augmentColor({color:{main:"#8f8f8f"}}),Ge.palette.augmentColor({color:{main:"#adadad"}}),Ge.palette.augmentColor({color:{main:"#d8d8d8"}}),Ge.palette.augmentColor({color:{main:"#d8d8d8"}}),Ge.palette.augmentColor({color:{main:"#adadad"}}),Ge.palette.augmentColor({color:{main:"#8f8f8f"}})],JH="#e22",KH="#3e3",XH="#800080",ZH="#808080",e9="#f00",t9="#00f",r9="#97b8c9",Bd={primary:jH,secondary:$H,tertiary:WH,quaternary:o2,highlight:o2,stopCodon:JH,startCodon:KH,insertion:XH,deletion:ZH,softclip:t9,hardclip:e9,bases:YH,frames:zH,framesCDS:qH,skip:r9};Vce={default:n9(),lightStock:o9(),lightMinimal:a9(),darkMinimal:s9(),darkStock:i9()}});var c2=m(()=>{});function Td(){return typeof window<"u"}function Do(e){return P0(e)?(e.nodeName||"").toLowerCase():"#document"}function Rt(e){var t;return(e==null||(t=e.ownerDocument)==null?void 0:t.defaultView)||window}function Zn(e){var t;return(t=(P0(e)?e.ownerDocument:e.document)||window.document)==null?void 0:t.documentElement}function P0(e){return Td()?e instanceof Node||e instanceof Rt(e).Node:!1}function Qt(e){return Td()?e instanceof Element||e instanceof Rt(e).Element:!1}function Hr(e){return Td()?e instanceof HTMLElement||e instanceof Rt(e).HTMLElement:!1}function dl(e){return!Td()||typeof ShadowRoot>"u"?!1:e instanceof ShadowRoot||e instanceof Rt(e).ShadowRoot}function Al(e){let{overflow:t,overflowX:r,overflowY:n,display:o}=Tr(e);return/auto|scroll|overlay|hidden|clip/.test(t+n+r)&&o!=="inline"&&o!=="contents"}function l2(e){return/^(table|td|th)$/.test(Do(e))}function ml(e){try{if(e.matches(":popover-open"))return!0}catch{}try{return e.matches(":modal")}catch{return!1}}function Md(e){let t=Qt(e)?Tr(e):e;return Ri(t.transform)||Ri(t.translate)||Ri(t.scale)||Ri(t.rotate)||Ri(t.perspective)||!pl()&&(Ri(t.backdropFilter)||Ri(t.filter))||c9.test(t.willChange||"")||l9.test(t.contain||"")}function u2(e){let t=Xn(e);for(;Hr(t)&&!Qi(t);){if(Md(t))return t;if(ml(t))return null;t=Xn(t)}return null}function pl(){return F0==null&&(F0=typeof CSS<"u"&&CSS.supports&&CSS.supports("-webkit-backdrop-filter","none")),F0}function Qi(e){return/^(html|body|#document)$/.test(Do(e))}function Tr(e){return Rt(e).getComputedStyle(e)}function gl(e){return Qt(e)?{scrollLeft:e.scrollLeft,scrollTop:e.scrollTop}:{scrollLeft:e.scrollX,scrollTop:e.scrollY}}function Xn(e){if(Do(e)==="html")return e;let t=e.assignedSlot||e.parentNode||dl(e)&&e.host||Zn(e);return dl(t)?t.host:t}function f2(e){let t=Xn(e);return Qi(t)?(e.ownerDocument||e).body:Hr(t)&&Al(t)?t:f2(t)}function ha(e,t,r){var n;t===void 0&&(t=[]),r===void 0&&(r=!0);let o=f2(e),i=o===((n=e.ownerDocument)==null?void 0:n.body),s=Rt(o);if(i){let a=Rd(s);return t.concat(s,s.visualViewport||[],Al(o)?o:[],a&&r?ha(a):[])}else return t.concat(o,ha(o,[],r))}function Rd(e){return e.parent&&Object.getPrototypeOf(e.parent)?e.frameElement:null}var c9,l9,Ri,F0,Qd=m(()=>{c9=/transform|translate|scale|rotate|perspective|filter/,l9=/paint|layout|strict|content/,Ri=e=>!!e&&e!=="none"});function O0(e,t){return typeof e=="function"?e(t):e}function G0(e){return e.split("-")[0]}function U0(e){return e.split("-")[1]}function d2(e){return e==="x"?"y":"x"}function A2(e){return e==="y"?"height":"width"}function kd(e){let t=e[0];return t==="t"||t==="b"?"y":"x"}function m2(e){return d2(kd(e))}function u9(e){var t,r,n,o;return{top:(t=e.top)!=null?t:0,right:(r=e.right)!=null?r:0,bottom:(n=e.bottom)!=null?n:0,left:(o=e.left)!=null?o:0}}function p2(e){return typeof e!="number"?u9(e):{top:e,right:e,bottom:e,left:e}}function ki(e){let{x:t,y:r,width:n,height:o}=e;return{width:n,height:o,top:r,left:t,right:t+n,bottom:r+o,x:t,y:r}}var _d,_i,hl,En,Dd=m(()=>{_d=Math.min,_i=Math.max,hl=Math.round,En=e=>({x:e,y:e})});function h2(e,t){if(!e||!t)return!1;let r=t.getRootNode==null?void 0:t.getRootNode();if(e.contains(t))return!0;if(r&&dl(r)){let n=t;for(;n;){if(e===n)return!0;n=n.parentNode||n.host}}return!1}function y2(e){return"composedPath"in e?e.composedPath()[0]:e.target}function x2(e,t){let r=["mouse","pen"];return t||r.push("",void 0),r.includes(e)}function Nd(e){let t=yl.useRef(()=>{});return p9(()=>{t.current=e}),yl.useCallback(function(){for(var r=arguments.length,n=new Array(r),o=0;o<r;o++)n[o]=arguments[o];return t.current==null?void 0:t.current(...n)},[])}var yl,g2,f9,d9,xl,A9,m9,p9,C2=m(()=>{Qd();yl=p(Q(),1),g2=p(Q(),1);f9=typeof document<"u",d9=function(){},xl=f9?g2.useLayoutEffect:d9,A9={...yl},m9=A9.useInsertionEffect,p9=m9||(e=>e())});function E2(e,t,r){let{reference:n,floating:o}=e,i=kd(t),s=m2(t),a=A2(s),c=G0(t),l=i==="y",u=n.x+n.width/2-o.width/2,d=n.y+n.height/2-o.height/2,A=n[a]/2-o[a]/2,f;switch(c){case"top":f={x:u,y:n.y-o.height};break;case"bottom":f={x:u,y:n.y+n.height};break;case"right":f={x:n.x+n.width,y:d};break;case"left":f={x:n.x-o.width,y:d};break;default:f={x:n.x,y:n.y}}let g=U0(t);return g&&(f[s]+=A*(g==="end"?1:-1)*(r&&l?-1:1)),f}async function b2(e,t){var r;t===void 0&&(t={});let{x:n,y:o,platform:i,rects:s,elements:a,strategy:c}=e,{boundary:l="clippingAncestors",rootBoundary:u="viewport",elementContext:d="floating",altBoundary:A=!1,padding:f=0}=O0(t,e),g=p2(f),x=a[A?d==="floating"?"reference":"floating":d],w=ki(await i.getClippingRect({element:(r=await(i.isElement==null?void 0:i.isElement(x)))==null||r?x:x.contextElement||await(i.getDocumentElement==null?void 0:i.getDocumentElement(a.floating)),boundary:l,rootBoundary:u,strategy:c})),y=d==="floating"?{x:n,y:o,width:s.floating.width,height:s.floating.height}:s.reference,v=await(i.getOffsetParent==null?void 0:i.getOffsetParent(a.floating)),b=await(i.isElement==null?void 0:i.isElement(v))&&await(i.getScale==null?void 0:i.getScale(v))||{x:1,y:1},I=ki(i.convertOffsetParentRelativeRectToViewportRelativeRect?await i.convertOffsetParentRelativeRectToViewportRelativeRect({elements:a,rect:y,offsetParent:v,strategy:c}):y);return{top:(w.top-I.top+g.top)/b.y,bottom:(I.bottom-w.bottom+g.bottom)/b.y,left:(w.left-I.left+g.left)/b.x,right:(I.right-w.right+g.right)/b.x}}async function y9(e,t){let{placement:r,platform:n,elements:o}=e,i=await(n.isRTL==null?void 0:n.isRTL(o.floating)),s=G0(r),a=U0(r),c=kd(r)==="y",l=h9.has(s)?-1:1,u=i&&c?-1:1,d=O0(t,e),{mainAxis:A,crossAxis:f,alignmentAxis:g}=typeof d=="number"?{mainAxis:d,crossAxis:0,alignmentAxis:null}:{mainAxis:d.mainAxis||0,crossAxis:d.crossAxis||0,alignmentAxis:d.alignmentAxis};return a&&typeof g=="number"&&(f=a==="end"?g*-1:g),c?{x:f*u,y:A*l}:{x:A*l,y:f*u}}var g9,w2,h9,I2,S2=m(()=>{Dd();Dd();g9=50,w2=async(e,t,r)=>{let{placement:n="bottom",strategy:o="absolute",middleware:i=[],platform:s}=r,a=s.detectOverflow?s:{...s,detectOverflow:b2},c=await(s.isRTL==null?void 0:s.isRTL(t)),l=await s.getElementRects({reference:e,floating:t,strategy:o}),{x:u,y:d}=E2(l,n,c),A=n,f=0,g={};for(let h=0;h<i.length;h++){let x=i[h];if(!x)continue;let{name:w,fn:y}=x,{x:v,y:b,data:I,reset:S}=await y({x:u,y:d,initialPlacement:n,placement:A,strategy:o,middlewareData:g,rects:l,platform:a,elements:{reference:e,floating:t}});u=v??u,d=b??d,g[w]={...g[w],...I},S&&f<g9&&(f++,typeof S=="object"&&(S.placement&&(A=S.placement),S.rects&&(l=S.rects===!0?await s.getElementRects({reference:e,floating:t,strategy:o}):S.rects),{x:u,y:d}=E2(l,A,c)),h=-1)}return{x:u,y:d,placement:A,strategy:o,middlewareData:g}},h9=new Set(["left","top"]);I2=function(e){return e===void 0&&(e=0),{name:"offset",options:e,async fn(t){var r,n;let{x:o,y:i,placement:s,middlewareData:a}=t,c=await y9(t,e);return s===((r=a.offset)==null?void 0:r.placement)&&(n=a.arrow)!=null&&n.alignmentOffset?{}:{x:o+c.x,y:i+c.y,data:{...c,placement:s}}}}}});function T2(e){let t=Tr(e),r=parseFloat(t.width)||0,n=parseFloat(t.height)||0,o=Hr(e),i=o?e.offsetWidth:r,s=o?e.offsetHeight:n,a=hl(r)!==i||hl(n)!==s;return a&&(r=i,n=s),{width:r,height:n,$:a}}function M2(e){return Qt(e)?e:e.contextElement}function ya(e){let t=M2(e);if(!Hr(t))return En(1);let r=t.getBoundingClientRect(),{width:n,height:o,$:i}=T2(t),s=(i?hl(r.width):r.width)/n,a=(i?hl(r.height):r.height)/o;return(!s||!Number.isFinite(s))&&(s=1),(!a||!Number.isFinite(a))&&(a=1),{x:s,y:a}}function R2(e){let t=Rt(e);return!pl()||!t.visualViewport?x9:{x:t.visualViewport.offsetLeft,y:t.visualViewport.offsetTop}}function C9(e,t,r){return t===void 0&&(t=!1),!!r&&t&&r===Rt(e)}function Cl(e,t,r,n){t===void 0&&(t=!1),r===void 0&&(r=!1);let o=e.getBoundingClientRect(),i=M2(e),s=En(1);t&&(n?Qt(n)&&(s=ya(n)):s=ya(e));let a=C9(i,r,n)?R2(i):En(0),c=(o.left+a.x)/s.x,l=(o.top+a.y)/s.y,u=o.width/s.x,d=o.height/s.y;if(i&&n){let A=Rt(i),f=Qt(n)?Rt(n):n,g=A,h=Rd(g);for(;h&&f!==g;){let x=ya(h),w=h.getBoundingClientRect(),y=Tr(h),v=w.left+(h.clientLeft+parseFloat(y.paddingLeft))*x.x,b=w.top+(h.clientTop+parseFloat(y.paddingTop))*x.y;c*=x.x,l*=x.y,u*=x.x,d*=x.y,c+=v,l+=b,g=Rt(h),h=Rd(g)}}return ki({width:u,height:d,x:c,y:l})}function Ld(e,t){let r=gl(e).scrollLeft;return t?t.left+r:Cl(Zn(e)).left+r}function Q2(e,t){let r=e.getBoundingClientRect(),n=r.left+t.scrollLeft-Ld(e,r),o=r.top+t.scrollTop;return{x:n,y:o}}function E9(e){let{elements:t,rect:r,offsetParent:n,strategy:o}=e,i=o==="fixed",s=Zn(n),a=t?ml(t.floating):!1;if(n===s||a&&i)return r;let c={scrollLeft:0,scrollTop:0},l=En(1),u=En(0),d=Hr(n);if((d||!i)&&((Do(n)!=="body"||Al(s))&&(c=gl(n)),d)){let f=Cl(n);l=ya(n),u.x=f.x+n.clientLeft,u.y=f.y+n.clientTop}let A=s&&!d&&!i?Q2(s,c):En(0);return{width:r.width*l.x,height:r.height*l.y,x:r.x*l.x-c.scrollLeft*l.x+u.x+A.x,y:r.y*l.y-c.scrollTop*l.y+u.y+A.y}}function b9(e){return e.getClientRects?Array.from(e.getClientRects()):[]}function w9(e){let t=gl(e),r=e.ownerDocument.body,n=_i(e.scrollWidth,e.clientWidth,r.scrollWidth,r.clientWidth),o=_i(e.scrollHeight,e.clientHeight,r.scrollHeight,r.clientHeight),i=-t.scrollLeft+Ld(e),s=-t.scrollTop;return Tr(r).direction==="rtl"&&(i+=_i(e.clientWidth,r.clientWidth)-n),{width:n,height:o,x:i,y:s}}function S9(e,t,r){r===void 0&&(r="viewport");let n=r==="layoutViewport",o=Rt(e),i=Zn(e),s=o.visualViewport,a=i.clientWidth,c=i.clientHeight,l=0,u=0;if(s){let A=!pl()||t==="fixed";n?A||(l=-s.offsetLeft,u=-s.offsetTop):(a=s.width,c=s.height,A&&(l=s.offsetLeft,u=s.offsetTop))}if(Ld(i)<=0){let A=i.ownerDocument,f=A.body,g=getComputedStyle(f),h=A.compatMode==="CSS1Compat"&&parseFloat(g.marginLeft)+parseFloat(g.marginRight)||0,x=Math.abs(i.clientWidth-f.clientWidth-h),w=getComputedStyle(i).scrollbarGutter==="stable both-edges"?x/2:x;w<=I9&&(a-=w)}return{width:a,height:c,x:l,y:u}}function v9(e,t){let r=Cl(e,!0,t==="fixed"),n=r.top+e.clientTop,o=r.left+e.clientLeft,i=ya(e),s=e.clientWidth*i.x,a=e.clientHeight*i.y,c=o*i.x,l=n*i.y;return{width:s,height:a,x:c,y:l}}function v2(e,t,r){let n;if(t==="viewport"||t==="layoutViewport")n=S9(e,r,t);else if(t==="document")n=w9(Zn(e));else if(Qt(t))n=v9(t,r);else{let o=R2(e);n={x:t.x-o.x,y:t.y-o.y,width:t.width,height:t.height}}return ki(n)}function B9(e,t){let r=t.get(e);if(r)return r;let n=ha(e,[],!1).filter(a=>Qt(a)&&Do(a)!=="body"),o=null,i=Tr(e).position==="fixed",s=i?Xn(e):e;for(;Qt(s)&&!Qi(s);){let a=Tr(s),c=Md(s),l=o?o.position:i?"fixed":"";!c&&(l==="fixed"||l==="absolute"&&a.position==="static")?n=n.filter(d=>d!==s):o=a,s=Xn(s)}return t.set(e,n),n}function T9(e){let{element:t,boundary:r,rootBoundary:n,strategy:o}=e,s=[...r==="clippingAncestors"?ml(t)?[]:B9(t,this._c):[].concat(r),n],a=v2(t,s[0],o),c=a.top,l=a.right,u=a.bottom,d=a.left;for(let A=1;A<s.length;A++){let f=v2(t,s[A],o);c=_i(f.top,c),l=_d(f.right,l),u=_d(f.bottom,u),d=_i(f.left,d)}return{width:l-d,height:u-c,x:d,y:c}}function M9(e){let{width:t,height:r}=T2(e);return{width:t,height:r}}function R9(e,t,r){let n=Hr(t),o=Zn(t),i=r==="fixed",s=Cl(e,!0,i,t),a={scrollLeft:0,scrollTop:0},c=En(0);if((n||!i)&&((Do(t)!=="body"||Al(o))&&(a=gl(t)),n)){let A=Cl(t,!0,i,t);c.x=A.x+t.clientLeft,c.y=A.y+t.clientTop}!n&&o&&(c.x=Ld(o));let l=o&&!n&&!i?Q2(o,a):En(0),u=s.left+a.scrollLeft-c.x-l.x,d=s.top+a.scrollTop-c.y-l.y;return{x:u,y:d,width:s.width,height:s.height}}function H0(e){return Tr(e).position==="static"}function B2(e,t){if(!Hr(e)||Tr(e).position==="fixed")return null;if(t)return t(e);let r=e.offsetParent;return Zn(e)===r&&(r=r.ownerDocument.body),r}function _2(e,t){let r=Rt(e);if(ml(e))return r;if(!Hr(e)){let o=Xn(e);for(;o&&!Qi(o);){if(Qt(o)&&!H0(o))return o;o=Xn(o)}return r}let n=B2(e,t);for(;n&&l2(n)&&H0(n);)n=B2(n,t);return n&&Qi(n)&&H0(n)&&!Md(n)?r:n||u2(e)||r}function _9(e){return Tr(e).direction==="rtl"}var x9,I9,Q9,k2,D2,V0,N2=m(()=>{S2();Dd();Qd();x9=En(0);I9=25;Q9=async function(e){let t=this.getOffsetParent||_2,r=this.getDimensions,n=await r(e.floating);return{reference:R9(e.reference,await t(e.floating),e.strategy),floating:{x:0,y:0,width:n.width,height:n.height}}};k2={convertOffsetParentRelativeRectToViewportRelativeRect:E9,getDocumentElement:Zn,getClippingRect:T9,getOffsetParent:_2,getElementRects:Q9,getClientRects:b9,getDimensions:M9,getScale:ya,isElement:Qt,isRTL:_9},D2=I2,V0=(e,t,r)=>{let n=new Map,o=r??{},i={...k2,...o.platform,_c:n};return w2(e,t,{...o,platform:i})}});function Pd(e,t){if(e===t)return!0;if(typeof e!=typeof t)return!1;if(typeof e=="function"&&e.toString()===t.toString())return!0;let r,n,o;if(e&&t&&typeof e=="object"){if(Array.isArray(e)){if(r=e.length,r!==t.length)return!1;for(n=r;n--!==0;)if(!Pd(e[n],t[n]))return!1;return!0}if(o=Object.keys(e),r=o.length,r!==Object.keys(t).length)return!1;for(n=r;n--!==0;)if(!{}.hasOwnProperty.call(t,o[n]))return!1;for(n=r;n--!==0;){let i=o[n];if(!(i==="_owner"&&e.$$typeof)&&!Pd(e[i],t[i]))return!1}return!0}return e!==e&&t!==t}function O2(e){return typeof window>"u"?1:(e.ownerDocument.defaultView||window).devicePixelRatio||1}function L2(e,t){let r=O2(e);return Math.round(t*r)/r}function j0(e){let t=tt.useRef(e);return Fd(()=>{t.current=e}),t}function G2(e){e===void 0&&(e={});let{placement:t="bottom",strategy:r="absolute",middleware:n=[],platform:o,elements:{reference:i,floating:s}={},transform:a=!0,whileElementsMounted:c,open:l}=e,[u,d]=tt.useState({x:0,y:0,strategy:r,placement:t,middlewareData:{},isPositioned:!1}),[A,f]=tt.useState(n);Pd(A,n)||f(n);let[g,h]=tt.useState(null),[x,w]=tt.useState(null),y=tt.useCallback(te=>{te!==S.current&&(S.current=te,h(te))},[]),v=tt.useCallback(te=>{te!==B.current&&(B.current=te,w(te))},[]),b=i||g,I=s||x,S=tt.useRef(null),B=tt.useRef(null),R=tt.useRef(u),D=c!=null,L=j0(c),P=j0(o),C=j0(l),M=tt.useCallback(()=>{if(!S.current||!B.current)return;let te={placement:t,strategy:r,middleware:A};P.current&&(te.platform=P.current),V0(S.current,B.current,te).then(kr=>{let ot={...kr,isPositioned:C.current!==!1};k.current&&!Pd(R.current,ot)&&(R.current=ot,P2.flushSync(()=>{d(ot)}))})},[A,t,r,P,C]);Fd(()=>{l===!1&&R.current.isPositioned&&(R.current.isPositioned=!1,d(te=>({...te,isPositioned:!1})))},[l]);let k=tt.useRef(!1);Fd(()=>(k.current=!0,()=>{k.current=!1}),[]),Fd(()=>{if(b&&(S.current=b),I&&(B.current=I),b&&I){if(L.current)return L.current(b,I,M);M()}},[b,I,M,L,D]);let G=tt.useMemo(()=>({reference:S,floating:B,setReference:y,setFloating:v}),[y,v]),j=tt.useMemo(()=>({reference:b,floating:I}),[b,I]),oe=tt.useMemo(()=>{let te={position:r,left:0,top:0};if(!j.floating)return te;let kr=L2(j.floating,u.x),ot=L2(j.floating,u.y);return a?{...te,transform:"translate("+kr+"px, "+ot+"px)",...O2(j.floating)>=1.5&&{willChange:"transform"}}:{position:r,left:kr,top:ot}},[r,a,j.floating,u.x,u.y]);return tt.useMemo(()=>({...u,update:M,refs:G,elements:j,floatingStyles:oe}),[u,M,G,j,oe])}var tt,F2,P2,k9,D9,Fd,Od,$0=m(()=>{N2();tt=p(Q(),1),F2=p(Q(),1),P2=p(Zf(),1),k9=typeof document<"u",D9=function(){},Fd=k9?F2.useLayoutEffect:D9;Od=(e,t)=>{let r=D2(e);return{name:r.name,fn:r.fn,options:[e,t]}}});function j9(){let[e,t]=z.useState(()=>V2?j2():void 0);return xl(()=>{e==null&&t(j2())},[]),z.useEffect(()=>{V2=!0},[]),e}function Y9(){let e=new Map;return{emit(t,r){var n;(n=e.get(t))==null||n.forEach(o=>o(r))},on(t,r){e.has(t)||e.set(t,new Set),e.get(t).add(r)},off(t,r){var n;(n=e.get(t))==null||n.delete(r)}}}function X9(e,t){let r=null,n=null,o=!1;return{contextElement:e||void 0,getBoundingClientRect(){var i;let s=e?.getBoundingClientRect()||{width:0,height:0,x:0,y:0},a=t.axis==="x"||t.axis==="both",c=t.axis==="y"||t.axis==="both",l=["mouseenter","mousemove"].includes(((i=t.dataRef.current.openEvent)==null?void 0:i.type)||"")&&t.pointerType!=="touch",u=s.width,d=s.height,A=s.x,f=s.y;return r==null&&t.x&&a&&(r=s.x-t.x),n==null&&t.y&&c&&(n=s.y-t.y),A-=r||0,f-=n||0,u=0,d=0,!o||l?(u=t.axis==="y"?s.width:0,d=t.axis==="x"?s.height:0,A=a&&t.x!=null?t.x:A,f=c&&t.y!=null?t.y:f):o&&!l&&(d=t.axis==="x"?s.height:d,u=t.axis==="y"?s.width:u),o=!0,{width:u,height:d,x:A,y:f,top:f,right:A+u,bottom:f+d,left:A}}}}function $2(e){return e!=null&&e.clientX!=null}function Y2(e,t){t===void 0&&(t={});let{open:r,dataRef:n,elements:{floating:o,domReference:i},refs:s}=e,{enabled:a=!0,axis:c="both",x:l=null,y:u=null}=t,d=z.useRef(!1),A=z.useRef(null),[f,g]=z.useState(),[h,x]=z.useState([]),w=Nd((S,B)=>{d.current||n.current.openEvent&&!$2(n.current.openEvent)||s.setPositionReference(X9(i,{x:S,y:B,axis:c,dataRef:n,pointerType:f}))}),y=Nd(S=>{l!=null||u!=null||(r?A.current||x([]):w(S.clientX,S.clientY))}),v=x2(f)?o:r,b=z.useCallback(()=>{if(!v||!a||l!=null||u!=null)return;let S=Rt(o);function B(R){let D=y2(R);h2(o,D)?(S.removeEventListener("mousemove",B),A.current=null):w(R.clientX,R.clientY)}if(!n.current.openEvent||$2(n.current.openEvent)){S.addEventListener("mousemove",B);let R=()=>{S.removeEventListener("mousemove",B),A.current=null};return A.current=R,R}s.setPositionReference(i)},[v,a,l,u,o,n,s,i,w]);z.useEffect(()=>b(),[b,h]),z.useEffect(()=>{a&&!o&&(d.current=!1)},[a,o]),z.useEffect(()=>{!a&&r&&(d.current=!0)},[a,r]),xl(()=>{a&&(l!=null||u!=null)&&(d.current=!1,w(l,u))},[a,l,u,w]);let I=z.useMemo(()=>{function S(B){let{pointerType:R}=B;g(R)}return{onPointerDown:S,onPointerEnter:S,onMouseMove:y,onMouseEnter:y}},[y]);return z.useMemo(()=>a?{reference:I}:{},[a,I])}function Z9(e){let{open:t=!1,onOpenChange:r,elements:n}=e,o=W9(),i=z.useRef({}),[s]=z.useState(()=>Y9()),a=J9()!=null,[c,l]=z.useState(n.reference),u=Nd((f,g,h)=>{i.current.openEvent=f?g:void 0,s.emit("openchange",{open:f,event:g,reason:h,nested:a}),r?.(f,g,h)}),d=z.useMemo(()=>({setPositionReference:l}),[]),A=z.useMemo(()=>({reference:c||n.reference||null,floating:n.floating||null,domReference:n.reference}),[c,n.reference,n.floating]);return z.useMemo(()=>({dataRef:i,open:t,onOpenChange:u,elements:A,events:s,floatingId:o,refs:d}),[t,u,A,s,o,d])}function q2(e){var t,r;let{elements:n,...o}=e===void 0?{}:e,{nodeId:i}=o,s=Z9({...o,elements:{reference:(t=n?.reference)!=null?t:null,floating:(r=n?.floating)!=null?r:null}}),a=o.rootContext||s,c=a.elements,[l,u]=z.useState(null),[d,A]=z.useState(null),g=c?.domReference||l,h=z.useRef(null),x=K9();xl(()=>{g&&(h.current=g)},[g]);let w=G2({...o,elements:{...c,...d&&{reference:d}}}),y=z.useCallback(B=>{let R=Qt(B)?{getBoundingClientRect:()=>B.getBoundingClientRect(),getClientRects:()=>B.getClientRects(),contextElement:B}:B;A(R),w.refs.setReference(R)},[w.refs]),v=z.useCallback(B=>{(Qt(B)||B===null)&&(h.current=B,u(B)),(Qt(w.refs.reference.current)||w.refs.reference.current===null||B!==null&&!Qt(B))&&w.refs.setReference(B)},[w.refs]),b=z.useMemo(()=>({...w.refs,setReference:v,setPositionReference:y,domReference:h}),[w.refs,v,y]),I=z.useMemo(()=>({...w.elements,domReference:g}),[w.elements,g]),S=z.useMemo(()=>({...w,...a,refs:b,elements:I,nodeId:i}),[w,b,I,i,a]);return xl(()=>{a.dataRef.current.floatingContext=S;let B=x?.nodesRef.current.find(R=>R.id===i);B&&(B.context=S)}),z.useMemo(()=>({...w,context:S,refs:b,elements:I}),[w,b,I,S])}function W0(e,t,r){let n=new Map,o=r==="item",i=e;if(o&&e){let{[U2]:s,[H2]:a,...c}=e;i=c}return{...r==="floating"&&{tabIndex:-1,[N9]:""},...i,...t.map(s=>{let a=s?s[r]:null;return typeof a=="function"?e?a(e):null:a}).concat(e).reduce((s,a)=>(a&&Object.entries(a).forEach(c=>{let[l,u]=c;if(!(o&&[U2,H2].includes(l)))if(l.indexOf("on")===0){if(n.has(l)||n.set(l,[]),typeof u=="function"){var d;(d=n.get(l))==null||d.push(u),s[l]=function(){for(var A,f=arguments.length,g=new Array(f),h=0;h<f;h++)g[h]=arguments[h];return(A=n.get(l))==null?void 0:A.map(x=>x(...g)).find(x=>x!==void 0)}}}else s[l]=u}),s),{})}}function z2(e){e===void 0&&(e=[]);let t=e.map(a=>a?.reference),r=e.map(a=>a?.floating),n=e.map(a=>a?.item),o=z.useCallback(a=>W0(a,e,"reference"),t),i=z.useCallback(a=>W0(a,e,"floating"),r),s=z.useCallback(a=>W0(a,e,"item"),n);return z.useMemo(()=>({getReferenceProps:o,getFloatingProps:i,getItemProps:s}),[o,i,s])}var z,Y0,W2,N9,U2,H2,L9,F9,P9,O9,G9,U9,Iue,H9,V2,V9,j2,$9,W9,q9,z9,J9,K9,J2=m(()=>{z=p(Q(),1);C2();Y0=p(O(),1);Qd();W2=p(Zf(),1);$0();$0();N9="data-floating-ui-focusable",U2="active",H2="selected",L9="ArrowLeft",F9="ArrowRight",P9="ArrowUp",O9="ArrowDown",G9=[L9,F9],U9=[P9,O9],Iue=[...G9,...U9],H9={...z},V2=!1,V9=0,j2=()=>"floating-ui-"+Math.random().toString(36).slice(2,6)+V9++;$9=H9.useId,W9=$9||j9;q9=z.createContext(null),z9=z.createContext(null),J9=()=>{var e;return((e=z.useContext(q9))==null?void 0:e.id)||null},K9=()=>z.useContext(z9)});function eV(e){return Math.round(e*1e5)/1e5}function z0({clientPoint:e,children:t,placement:r="right"}){let o=(0,xa.useTheme)().components?.MuiPopper,{classes:i}=tV(),{refs:s,floatingStyles:a,context:c}=q2({placement:r,strategy:"fixed",middleware:[Od(5)]}),l=Y2(c,e),{getFloatingProps:u}=z2([l]);return(0,q0.jsx)(xa.Portal,{container:o?.defaultProps?.container,children:(0,q0.jsx)("div",{className:i.tooltip,ref:s.setFloating,style:{...a,zIndex:1e5,visibility:a.transform==="translate(0px, 0px)"?"hidden":void 0,pointerEvents:"none"},...u(),children:t})})}var q0,xa,tV,K2=m(()=>{q0=p(O(),1);J2();xa=p(U(),1);He();tV=Z()(e=>({tooltip:{position:"absolute",pointerEvents:"none",backgroundColor:(0,xa.alpha)(e.palette.grey[700],.9),borderRadius:e.shape.borderRadius,color:e.palette.common.white,fontFamily:e.typography.fontFamily,padding:"4px 8px",fontSize:e.typography.fontSize,lineHeight:`${eV(14/10)}em`,maxWidth:300,wordWrap:"break-word"}}))});var X2=m(()=>{});var J0=m(()=>{a2();l0();c2();X2()});function No({value:e}){let{classes:t}=rV(),r=/^https?:\/\//.exec(`${e}`);return(0,Gd.jsx)("div",{className:t.fieldValue,children:(0,Z2.isValidElement)(e)?e:r?(0,Gd.jsx)(eQ.Link,{href:`${e}`,children:`${e}`}):(0,Gd.jsx)(vo,{html:Br(e)?JSON.stringify(e):String(e)})})}var Gd,Z2,eQ,rV,Ud=m(()=>{Gd=p(O(),1),Z2=p(Q(),1),eQ=p(U(),1);J0();bo();He();rV=Z()(e=>({fieldValue:{wordBreak:"break-word",maxHeight:300,fontSize:12,padding:e.spacing(.5),overflow:"auto"}}))});function bn({description:e,name:t,width:r,prefix:n=[]}){let{classes:o}=nV(),i=[...n,t].join(".");return e?(0,Hd.jsx)(tQ.Tooltip,{title:e,placement:"left",children:(0,Hd.jsx)("div",{className:Mf(o.fieldDescription,o.fieldName),children:i})}):(0,Hd.jsx)("div",{className:o.fieldName,style:{width:r},children:i})}var Hd,tQ,nV,El=m(()=>{Hd=p(O(),1),tQ=p(U(),1);He();nV=Z()(e=>({fieldDescription:{"&:hover":{background:e.palette.mode==="dark"?"#e65100":"yellow"}},fieldName:{wordBreak:"break-all",minWidth:90,borderBottom:"1px solid #0003",fontSize:12,background:e.palette.action.disabledBackground,marginRight:e.spacing(1),padding:e.spacing(.5)}}))});function X0({name:e,value:t,description:r,formatter:n,prefix:o=[]}){let{classes:i}=oV(),[s,a]=(0,rQ.useState)(!1),c=t.length>K0,l=c&&!s?t.slice(0,K0):t;return t.length===1?Br(t[0])?(0,jt.jsx)(wn,{formatter:n,attributes:t[0],prefix:[...o,e]}):(0,jt.jsxs)("div",{className:i.field,children:[(0,jt.jsx)(bn,{prefix:o,description:r,name:e}),(0,jt.jsx)(No,{value:n?n(t[0],e):t[0]})]}):t.every(u=>Br(u))?(0,jt.jsx)(jt.Fragment,{children:t.map((u,d)=>(0,jt.jsx)(wn,{formatter:n,attributes:u,prefix:[...o,`${e}-${d}`]},`${JSON.stringify(u)}-${d}`))}):(0,jt.jsxs)("div",{className:i.field,children:[(0,jt.jsx)(bn,{prefix:o,description:r,name:e}),l.map((u,d)=>(0,jt.jsx)("div",{className:i.fieldSubvalue,children:(0,jt.jsx)(No,{value:n?n(u,e):u})},`${JSON.stringify(u)}-${d}`)),c?(0,jt.jsx)("button",{type:"button",onClick:()=>{a(u=>!u)},children:s?"Show less":`Showing ${K0} of ${t.length}. Show all...`}):null]})}var jt,rQ,K0,oV,nQ=m(()=>{jt=p(O(),1),rQ=p(Q(),1);Vd();Ud();El();bo();He();K0=100,oV=Z()(e=>({field:{display:"flex",flexWrap:"wrap"},fieldSubvalue:{wordBreak:"break-word",maxHeight:300,padding:e.spacing(.5),border:`1px solid ${e.palette.action.selected}`,boxSizing:"border-box",overflow:"auto"}}))});var iQ=X((Yue,oQ)=>{oQ.exports=JBrowseExports["@mui/x-data-grid"]});function Z0({children:e,style:t}){let{classes:r}=iV();return(0,sQ.jsx)("div",{className:r.flexContainer,style:t,children:e})}var sQ,iV,aQ=m(()=>{sQ=p(O(),1);He();iV=Z()({flexContainer:{display:"flex",flexDirection:"column"}})});function ey({value:e,prefix:t,name:r}){let{classes:n}=sV(),[o,i]=(0,cQ.useState)(!1),s=Object.keys(e[0]).sort(),a=new Set(s),c=Object.entries(e).map(([d,A])=>{let{id:f,...g}=A;return{id:d,identifier:f,...g}});for(let d of e)for(let A of Object.keys(d))a.add(A);let l;a.has("id")?(a.delete("id"),l=["identifier",...a]):l=[...a];let u=l.map(d=>QT(c.map(A=>A[d])));return a.size<s.length+5?(0,Vr.jsxs)("div",{className:n.margin,children:[(0,Vr.jsx)(bn,{prefix:t,name:r}),(0,Vr.jsx)(Ca.FormControlLabel,{control:(0,Vr.jsx)(Ca.Checkbox,{checked:o,onChange:d=>{i(d.target.checked)}}),label:(0,Vr.jsx)(Ca.Typography,{variant:"body2",children:"Show options"})}),(0,Vr.jsx)(Z0,{children:(0,Vr.jsx)(lQ.DataGrid,{disableRowSelectionOnClick:!0,rows:c,rowHeight:20,columnHeaderHeight:35,hideFooter:c.length<25,showToolbar:o,columns:l.map((d,A)=>({field:d,width:u[A],renderCell:({value:f})=>(0,Vr.jsx)("div",{className:n.cell,children:(0,Vr.jsx)(vo,{html:e0(f||"")})})}))})})]}):null}var Vr,cQ,Ca,lQ,sV,uQ=m(()=>{Vr=p(O(),1),cQ=p(Q(),1),Ca=p(U(),1),lQ=p(iQ(),1);El();aQ();J0();bo();He();sV=Z()(e=>({margin:{marginBottom:e.spacing(4)},cell:{whiteSpace:"nowrap",overflow:"hidden",textOverflow:"ellipsis"}}))});function ty({name:e,value:t,description:r,prefix:n,width:o,formatter:i}){let{classes:s}=aV();return t!=null?(0,bl.jsxs)("div",{className:s.field,children:[(0,bl.jsx)(bn,{prefix:n,description:r,name:e,width:o}),(0,bl.jsx)(No,{value:i?i(t,e):t})]}):null}var bl,aV,fQ=m(()=>{bl=p(O(),1);Ud();El();He();aV=Z()({field:{display:"flex",flexWrap:"wrap"}})});function ry({value:e,prefix:t,name:r}){let{classes:n}=cV(),{uri:o,baseUri:i=""}=e,s;try{s=new URL(o,i).href}catch{s=o}return(0,wl.jsxs)("div",{className:n.field,children:[(0,wl.jsx)(bn,{prefix:t,name:r}),(0,wl.jsx)(No,{value:s})]})}var wl,cV,dQ=m(()=>{wl=p(O(),1);Ud();El();He();cV=Z()({field:{display:"flex",flexWrap:"wrap"}})});function AQ(e,t){return e.map(r=>t.slice(r.start,r.end)).join("")}var mQ=m(()=>{});function pQ(e,t){return Math.ceil(t0(e.map(r=>Xh([...t,r[0]].join("."),12))))+10}function gQ(e,t={}){let r=t;for(let n of e)Br(r)&&(r=r[n]);return typeof r=="string"?r:Br(r)&&typeof r.Description=="string"?r.Description:void 0}var hQ=m(()=>{bo()});function wn(e){let{attributes:t,omit:r=[],omitSingleLevel:n=[],descriptions:o,formatter:i,hideUris:s,prefix:a=[]}=e,c=new Set([...r,...uV,...n]),{__jbrowsefmt:l,...u}=t,d=Object.entries({...u,...l}).filter(([f,g])=>g!=null&&!c.has(f)),A=pQ(d,a);return(0,eo.jsx)(eo.Fragment,{children:d.map(([f,g])=>{let h=gQ([...a,f],o);if(Array.isArray(g))return g.length>1&&g.every(x=>Br(x))?(0,eo.jsx)(ey,{name:f,prefix:a,value:g},f):(0,eo.jsx)(X0,{name:f,value:g,formatter:i,description:h,prefix:a},f);if(Br(g)){let{omitSingleLevel:x,...w}=e;return ed(g)?s?null:(0,eo.jsx)(ry,{name:f,prefix:a,value:g},f):(0,eo.jsx)(wn,{...w,formatter:i,attributes:g,descriptions:o,prefix:[...a,f]},f)}else return(0,eo.jsx)(ty,{name:f,formatter:i,value:g,description:h,prefix:a,width:Math.min(A,lV)},f)})})}var eo,lV,uV,Vd=m(()=>{eo=p(O(),1);nQ();uQ();fQ();dQ();hQ();bo();lV=170,uV=["__jbrowsefmt","length","position","subfeatures","uniqueId","exonFrames","parentId","thickStart","thickEnd","_lineHash"]});var yQ,xQ,CQ=m(()=>{"use client";or();yQ=p(O(),1),xQ=(0,Te.createSvgIcon)((0,yQ.jsx)("path",{d:"M16.59 8.59 12 13.17 7.41 8.59 6 10l6 6 6-6z"}),"ExpandMore")});function Ni({children:e,title:t,defaultExpanded:r=!0}){let{classes:n}=fV();return(0,Di.jsxs)(Lo.Accordion,{defaultExpanded:r,children:[(0,Di.jsx)(Lo.AccordionSummary,{expandIcon:(0,Di.jsx)(xQ,{className:n.icon}),children:(0,Di.jsx)(Lo.Typography,{variant:"button",children:t})}),(0,Di.jsx)(Lo.AccordionDetails,{className:n.expansionPanelDetails,children:e})]})}var Di,Lo,fV,ny=m(()=>{Di=p(O(),1);CQ();Lo=p(U(),1);He();fV=Z()(e=>({expansionPanelDetails:{display:"block",padding:e.spacing(1)},icon:{color:e.palette.tertiary.contrastText||"#fff"}}))});function Li({checked:e,label:t,disabled:r,onChange:n}){return jd.default.createElement("div",null,jd.default.createElement($d.FormControlLabel,{control:jd.default.createElement($d.Checkbox,{disabled:r,checked:e,onChange:()=>{n()}}),label:t}))}var jd,$d,oy=m(()=>{jd=p(Q(),1),$d=p(U(),1)});function Il({str:e}){let{classes:t}=dV(),[r,n]=(0,jr.useState)(!1),[o,i]=(0,jr.useState)(!1),[s,a]=(0,jr.useState)(!1),c=e.map(([l,u])=>[l,o?u:ll(u)]).filter(([,l])=>s||!!l).map(([l,u])=>`>${l}
+${u}`).join(`
+`);return jr.default.createElement(jr.default.Fragment,null,jr.default.createElement(Wd.Button,{color:"primary",variant:"contained",onClick:()=>{Oc(c),n(!0),setTimeout(()=>{n(!1)},500)}},r?"Copied!":"Copy to clipboard"),jr.default.createElement(Li,{label:"Show gaps",checked:o,onChange:()=>{i(!o)}}),jr.default.createElement(Li,{label:"Show empty",checked:s,onChange:()=>{a(!s)}}),jr.default.createElement(Wd.TextField,{variant:"outlined",multiline:!0,className:t.dialogContent,minRows:5,maxRows:10,fullWidth:!0,value:c,slotProps:{input:{readOnly:!0,className:t.textAreaFont}}}))}var jr,Wd,dV,iy=m(()=>{jr=p(Q(),1);He();Wd=p(U(),1);Sd();Tg();oy();dV=Z()({textAreaFont:{fontFamily:"Courier New",wordWrap:"break-word"},dialogContent:{background:"lightgrey",margin:4,minWidth:"80em"}})});var IQ={};Bt(IQ,{default:()=>mV});var Ea,EQ,bQ,wQ,AV,mV,SQ=m(()=>{Ea=p(Q(),1);Vd();ny();EQ=p(Xe(),1),bQ=p(U(),1),wQ=p(Y(),1);iy();AV=(0,wQ.observer)(function({model:e,onClose:t}){let{header:r}=e;return Ea.default.createElement(EQ.Dialog,{onClose:()=>{t()},open:!0,title:"Metadata",maxWidth:"xl"},Ea.default.createElement(bQ.DialogContent,null,Ea.default.createElement(wn,{attributes:r}),Ea.default.createElement(Ni,{title:"sequence"},Ea.default.createElement(Il,{str:e.rows}))))}),mV=AV});var BQ={};Bt(BQ,{default:()=>vQ});function vQ({model:e,onClose:t}){let[r,n]=(0,Le.useState)(!0),[o,i]=(0,Le.useState)(!0),[s,a]=(0,Le.useState)("viewport"),[c,l]=(0,Le.useState)(),u=(0,Qe.useTheme)(),{totalWidth:d,totalHeight:A,treeAreaWidth:f,turnedOnTracks:g,totalTrackAreaHeight:h}=e,x=g.length>0,w=d+f,y=A+(o?h:0),v=s==="entire"&&(w>1e4||y>1e4);return Le.default.createElement(Yd.Dialog,{onClose:()=>{t()},open:!0,title:"Export SVG"},Le.default.createElement(Qe.DialogContent,null,c?Le.default.createElement(Yd.ErrorMessage,{error:c}):null,Le.default.createElement(Qe.Typography,null,"Settings:"),Le.default.createElement(Li,{label:"Include minimap?",disabled:s==="entire",checked:r,onChange:()=>{n(!r)}}),x?Le.default.createElement(Li,{label:"Include tracks?",checked:o,onChange:()=>{i(!o)}}):null,Le.default.createElement("div",null,Le.default.createElement(Qe.FormControl,null,Le.default.createElement(Qe.FormLabel,null,"Export type"),Le.default.createElement(Qe.RadioGroup,{value:s,onChange:b=>{let{value:I}=b.target;(I==="entire"||I==="viewport")&&a(I)}},Le.default.createElement(Qe.FormControlLabel,{value:"entire",control:Le.default.createElement(Qe.Radio,null),label:"Entire MSA"}),Le.default.createElement(Qe.FormControlLabel,{value:"viewport",control:Le.default.createElement(Qe.Radio,null),label:"Current viewport only"})))),v?Le.default.createElement(Qe.Alert,{severity:"warning",style:{marginTop:8}},"The entire MSA is very large (",Math.round(w),"x",Math.round(y)," pixels). Export may be slow or fail."):null),Le.default.createElement(Qe.DialogActions,null,Le.default.createElement(Qe.Button,{variant:"contained",color:"primary",onClick:()=>{e.exportSVG({theme:u,includeMinimap:s==="entire"?!1:r,includeTracks:x&&o,exportType:s}).then(()=>{t()}).catch(b=>{console.error(b),l(b)})}},"Submit"),Le.default.createElement(Qe.Button,{variant:"contained",color:"secondary",onClick:()=>{t()}},"Cancel")))}var Le,Yd,Qe,TQ=m(()=>{Le=p(Q(),1),Yd=p(Xe(),1),Qe=p(U(),1);oy()});var ba,MQ,pV,gV,hV,RQ,QQ=m(()=>{ba=p(Q(),1);Aa();qM();g0();XM();eR();MQ=p(Y(),1);YR();pV=(0,ba.lazy)(()=>Promise.resolve().then(()=>(SQ(),IQ))),gV=(0,ba.lazy)(()=>Promise.resolve().then(()=>(TQ(),BQ))),hV=(0,MQ.observer)(({model:e})=>ba.default.createElement(Cn,{"data-testid":"file_menu",tooltip:"File",menuItems:[{label:"Return to import form",icon:yd,onClick:()=>{e.reset()}},{label:"Metadata",icon:YM,onClick:()=>{e.queueDialog(t=>[pV,{model:e,onClose:t}])}},{label:"Domain settings",type:"subMenu",subMenu:WR({model:e})},{label:"Export SVG",icon:ZM,onClick:()=>{e.queueDialog(t=>[gV,{onClose:t,model:e}])}}],anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"}},ba.default.createElement(KM,null))),RQ=hV});var qd,zd,_Q,yV,kQ,DQ=m(()=>{qd=p(Q(),1),zd=p(U(),1),_Q=p(Y(),1),yV=(0,_Q.observer)(function({model:t}){let{hideGaps:r,allowedGappyness:n}=t;return r?qd.default.createElement("div",{style:{display:"flex",alignItems:"center",gap:8}},qd.default.createElement(zd.Typography,{style:{whiteSpace:"nowrap"}},"Hide columns w/ >",n,"% gaps"),qd.default.createElement(zd.Slider,{"data-testid":"gappyness_slider",style:{width:100},min:1,max:100,value:n,onChange:(o,i)=>{t.setAllowedGappyness(i)}})):null}),kQ=yV});var Jd,NQ,LQ,xV,CV,FQ,PQ=m(()=>{Jd=p(Q(),1);He();NQ=p(U(),1),LQ=p(Y(),1),xV=Z()({container:{display:"flex",overflow:"hidden",margin:"auto",marginLeft:10},nameFirst:{overflow:"hidden",textOverflow:"ellipsis",whiteSpace:"nowrap",minWidth:0},nameRest:{whiteSpace:"nowrap",flexShrink:0}}),CV=(0,LQ.observer)(function({model:e}){let{mouseOverRowName:t,mouseCol:r}=e,{classes:n}=xV();if(!t||r===void 0)return null;let o=Math.floor(t.length/2),i=e.visibleColToSeqPosOneBased(t,r),s=e.visibleColToRowLetter(t,r);return Jd.default.createElement(NQ.Typography,{component:"div",className:n.container,title:t},Jd.default.createElement("span",{className:n.nameFirst},t.slice(0,o)),Jd.default.createElement("span",{className:n.nameRest},t.slice(o),":",i," (",s,")"))}),FQ=CV});var Sl,OQ,Kd,GQ,EV,bV,UQ,HQ=m(()=>{Sl=p(Q(),1),OQ=p(Xe(),1);He();Kd=p(U(),1),GQ=p(Y(),1),EV=Z()({margin:{margin:"auto",marginLeft:10}}),bV=(0,GQ.observer)(({model:e})=>{let{status:t}=e,{classes:r}=EV();return t?Sl.default.createElement(Kd.Typography,{className:r.margin},Sl.default.createElement(OQ.LoadingEllipses,{message:t.msg,component:"span"})," ",t.url?Sl.default.createElement("a",{href:t.url,target:"_blank",rel:"noreferrer"},"(status)"):null," ",t.onCancel?Sl.default.createElement(Kd.Button,{size:"small",onClick:()=>t.onCancel?.()},"Cancel"):null):null}),UQ=bV});var VQ,jQ,$Q=m(()=>{"use client";we();VQ=p(O(),1),jQ=W((0,VQ.jsx)("path",{d:"M3 17v2h6v-2zM3 5v2h10V5zm10 16v-2h8v-2h-8v-2h-2v6zM7 9v2H3v2h4v2h2V9zm14 4v-2H11v2zm-6-4h2V7h4V5h-4V3h-2z"}),"Tune")});function WQ(e){let{drawMsaLetters:t,hideGaps:r,bgColor:n,showColumnStats:o}=e;return[{label:"Show column statistics on hover",type:"checkbox",checked:o,onClick:()=>{e.setShowColumnStats(!o)}},{label:"Draw letters",type:"checkbox",checked:t,onClick:()=>{e.setDrawMsaLetters(!t)}},{label:"Color letters instead of background of tiles",type:"checkbox",checked:!n,onClick:()=>{e.setBgColor(!n)}},{label:"Enable hiding gappy columns?",type:"checkbox",checked:r,onClick:()=>{e.setHideGaps(!r)}}]}function YQ(e){let{drawTree:t,showBranchLen:r,labelsAlignRight:n,drawNodeBubbles:o,drawLabels:i}=e;return[{label:"Show branch length",type:"checkbox",checked:r,onClick:()=>{e.setShowBranchLen(!r)}},{label:"Show tree",type:"checkbox",checked:t,onClick:()=>{e.setDrawTree(!t)}},{label:"Draw clickable bubbles on tree branches",type:"checkbox",checked:o,onClick:()=>{e.setDrawNodeBubbles(!o)}},{label:"Tree labels align right",type:"checkbox",checked:n,onClick:()=>{e.setLabelsAlignRight(!n)}},{label:"Draw labels",type:"checkbox",checked:i,onClick:()=>{e.setDrawLabels(!i)}}]}var sy=m(()=>{});var ay,qQ,wV,zQ,JQ=m(()=>{ay=p(Q(),1);Aa();$Q();qQ=p(Y(),1);sy();wV=(0,qQ.observer)(function({model:e}){return ay.default.createElement(Cn,{"data-testid":"msa_settings_menu",tooltip:"Alignment settings",closeAfterItemClick:!1,anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"},menuItems:WQ(e)},ay.default.createElement(jQ,null))}),zQ=wV});var cy,Xd,KQ,IV,XQ,ZQ=m(()=>{cy=p(Q(),1),Xd=p(U(),1),KQ=p(Y(),1),IV=(0,KQ.observer)(function({model:e}){let{currentAlignment:t,alignmentNames:r}=e,n=new Map;return r.length>0?cy.default.createElement(Xd.TextField,{select:!0,variant:"outlined",value:t,size:"small",onChange:o=>{e.setCurrentAlignment(+o.target.value),e.setScrollX(0),e.setScrollY(0)}},r.map((o,i)=>{let s=n.get(o)??0;return n.set(o,s+1),cy.default.createElement(Xd.MenuItem,{key:s===0?o:`${o}\0${s}`,value:i},o)})):null}),XQ=IV});var e_,t_,r_=m(()=>{"use client";we();e_=p(O(),1),t_=W((0,e_.jsx)("path",{d:"M22 11V3h-7v3H9V3H2v8h7V8h2v10h4v3h7v-8h-7v3h-2V8h2v3z"}),"AccountTree")});var ly,n_,SV,o_,i_=m(()=>{ly=p(Q(),1);Aa();r_();n_=p(Y(),1);sy();SV=(0,n_.observer)(function({model:e}){let{rows:t}=e;return ly.default.createElement(Cn,{"data-testid":"tree_settings_menu",tooltip:"Tree settings",closeAfterItemClick:!1,anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"},menuItems:[...YQ(e),...t.length>=2?[{label:"Advanced",type:"subMenu",subMenu:[{label:"Calculate neighbor joining tree (BLOSUM62)",onClick:()=>{try{e.calculateNeighborJoiningTreeFromMSA()}catch(r){console.error("Failed to calculate NJ tree:",r),e.setError(r)}}}]}]:[]]},ly.default.createElement(t_,null))}),o_=SV});var s_,a_,c_=m(()=>{"use client";we();s_=p(O(),1),a_=W((0,s_.jsx)("path",{d:"M13 1.07V9h7c0-4.08-3.05-7.44-7-7.93M4 15c0 4.42 3.58 8 8 8s8-3.58 8-8v-4H4zm7-13.93C7.05 1.56 4 4.92 4 9h7z"}),"Mouse")});var uy,l_,u_=m(()=>{"use client";we();uy=p(O(),1),l_=W([(0,uy.jsx)("path",{d:"M15.5 14h-.79l-.28-.27C15.41 12.59 16 11.11 16 9.5 16 5.91 13.09 3 9.5 3S3 5.91 3 9.5 5.91 16 9.5 16c1.61 0 3.09-.59 4.23-1.57l.27.28v.79l5 4.99L20.49 19zm-6 0C7.01 14 5 11.99 5 9.5S7.01 5 9.5 5 14 7.01 14 9.5 11.99 14 9.5 14"},"0"),(0,uy.jsx)("path",{d:"M12 10h-2v2H9v-2H7V9h2V7h1v2h2z"},"1")],"ZoomIn")});var f_,d_,A_=m(()=>{"use client";we();f_=p(O(),1),d_=W((0,f_.jsx)("path",{d:"M15.5 14h-.79l-.28-.27C15.41 12.59 16 11.11 16 9.5 16 5.91 13.09 3 9.5 3S3 5.91 3 9.5 5.91 16 9.5 16c1.61 0 3.09-.59 4.23-1.57l.27.28v.79l5 4.99L20.49 19zm-6 0C7.01 14 5 11.99 5 9.5S7.01 5 9.5 5 14 7.01 14 9.5 11.99 14 9.5 14M7 9h5v1H7z"}),"ZoomOut")});var $r,Fo,m_,vV,p_,g_=m(()=>{$r=p(Q(),1);c_();u_();A_();Fo=p(U(),1),m_=p(Y(),1),vV=(0,m_.observer)(function({model:t}){return $r.default.createElement($r.default.Fragment,null,$r.default.createElement(Fo.Tooltip,{title:"Zoom in"},$r.default.createElement(Fo.IconButton,{"aria-label":"Zoom in",onClick:()=>{t.zoomIn()}},$r.default.createElement(l_,null))),$r.default.createElement(Fo.Tooltip,{title:"Zoom out"},$r.default.createElement(Fo.IconButton,{"aria-label":"Zoom out",onClick:()=>{t.zoomOut()}},$r.default.createElement(d_,null))),$r.default.createElement(Fo.ToggleButton,{value:"scrollZoom",selected:t.scrollZoom,"aria-label":"Toggle scroll-to-zoom",title:"Toggle scroll-to-zoom (zoom on plain mouse wheel; ctrl+wheel always zooms)",size:"small",sx:{border:"none"},onChange:()=>{t.setScrollZoom(!t.scrollZoom)}},$r.default.createElement(a_,null)))}),p_=vV});var h_,y_,x_=m(()=>{"use client";we();h_=p(O(),1),y_=W((0,h_.jsx)("path",{d:"M12 8c1.1 0 2-.9 2-2s-.9-2-2-2-2 .9-2 2 .9 2 2 2m0 2c-1.1 0-2 .9-2 2s.9 2 2 2 2-.9 2-2-.9-2-2-2m0 6c-1.1 0-2 .9-2 2s.9 2 2 2 2-.9 2-2-.9-2-2-2"}),"MoreVert")});var C_,E_,b_=m(()=>{"use client";we();C_=p(O(),1),E_=W((0,C_.jsx)("path",{d:"M12 5V2L8 6l4 4V7c3.31 0 6 2.69 6 6 0 2.97-2.17 5.43-5 5.91v2.02c3.95-.49 7-3.85 7-7.93 0-4.42-3.58-8-8-8m-6 8c0-1.65.67-3.15 1.76-4.24L6.34 7.34C4.9 8.79 4 10.79 4 13c0 4.08 3.05 7.44 7 7.93v-2.02c-2.83-.48-5-2.94-5-5.91"}),"RestartAlt")});var fy,w_,BV,I_,S_=m(()=>{fy=p(Q(),1);Aa();x_();b_();w_=p(Y(),1),BV=(0,w_.observer)(function({model:e}){return fy.default.createElement(Cn,{tooltip:"Fit / zoom options",menuItems:[{label:"Fit both vertically/horizontally",onClick:()=>{e.fit()}},{label:"Fit vertically",onClick:()=>{e.fitVertically()}},{label:"Fit horizontally",onClick:()=>{e.fitHorizontally()}},{label:"Reset zoom to default",icon:E_,onClick:()=>{e.resetZoom()}}]},fy.default.createElement(y_,null))}),I_=BV});var v_,B_=m(()=>{v_="5.9.0"});var R_={};Bt(R_,{default:()=>M_});function M_({onClose:e}){return st.default.createElement(T_.Dialog,{open:!0,title:"About",onClose:()=>{e()}},st.default.createElement($t.DialogContent,null,st.default.createElement($t.Typography,null,"MSAView ",v_," (",st.default.createElement($t.Link,{href:"https://github.com/gmod/react-msaview"},"Github"),")"),st.default.createElement("ul",null,st.default.createElement("li",null,st.default.createElement($t.Typography,null,"We use some color schemes from the"," ",st.default.createElement($t.Link,{href:"https://github.com/biotite-dev/biotite"},"biotite")," ","project, and their license is reproduced"," ",st.default.createElement($t.Link,{href:"https://github.com/biotite-dev/biotite/blob/master/LICENSE.rst"},"here"))),st.default.createElement("li",null,st.default.createElement($t.Typography,null,"See this page for some information on jalview colorings"," ",st.default.createElement($t.Link,{href:"https://www.jalview.org/help/html/colourSchemes/"},"here"))),st.default.createElement("li",null,st.default.createElement($t.Typography,null,"See this page for some info on the clustal, cinema, maeditor, and lesk color schemes"," ",st.default.createElement($t.Link,{href:"http://www.bioinformatics.nl/~berndb/aacolour.html"},"here"))),st.default.createElement("li",null,st.default.createElement($t.Typography,null,"See this paper about the flower color scheme"," ",st.default.createElement($t.Link,{href:"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245768/"},"here"))))))}var st,T_,$t,Q_=m(()=>{st=p(Q(),1),T_=p(Xe(),1),$t=p(U(),1);B_()});function RV(){return Ve.default.createElement("div",{style:{flex:1}})}var Ve,Zd,__,TV,MV,k_,D_=m(()=>{Ve=p(Q(),1);OS();HS();Zd=p(U(),1),__=p(Y(),1);$M();QQ();DQ();PQ();HQ();JQ();ZQ();i_();g_();S_();TV=(0,Ve.lazy)(()=>Promise.resolve().then(()=>(Q_(),R_))),MV=(0,__.observer)(function({model:e}){let[t,{height:r}]=Rg();return(0,Ve.useEffect)(()=>{e.setHeaderHeight(r??0)},[e,r]),Ve.default.createElement("div",{ref:t,style:{display:"flex"}},Ve.default.createElement(RQ,{model:e}),Ve.default.createElement(jM,{model:e}),Ve.default.createElement(o_,{model:e}),Ve.default.createElement(zQ,{model:e}),Ve.default.createElement(p_,{model:e}),Ve.default.createElement(I_,{model:e}),Ve.default.createElement(kQ,{model:e}),Ve.default.createElement("div",{style:{paddingLeft:20,margin:"auto"}},Ve.default.createElement(XQ,{model:e})),Ve.default.createElement(FQ,{model:e}),Ve.default.createElement(RV,null),Ve.default.createElement(UQ,{model:e}),Ve.default.createElement(Zd.Tooltip,{title:"About"},Ve.default.createElement(Zd.IconButton,{"aria-label":"About",onClick:()=>{e.queueDialog(n=>[TV,{onClose:n}])}},Ve.default.createElement(US,null))))});k_=MV});var In,N_,QV,L_,F_=m(()=>{In=p(Q(),1),N_=p(Y(),1);Bf();$p();QV=(0,N_.observer)(function({model:e}){let[t,r]=(0,In.useState)(!1),{minimapHeight:n}=e,{unit:o,s:i,w:s,polygonHeight:a,polygonPoints:c}=cf(e),l="rgba(66, 119, 127, 0.3)",{startDrag:u}=yo("x",(0,In.useCallback)((d,A)=>{e.setScrollX(A-d/o)},[e,o]));return In.default.createElement("div",{style:{position:"relative",height:n,width:"100%"}},In.default.createElement("div",{style:{height:12,boxSizing:"border-box",border:"1px solid #555"}}),In.default.createElement("div",{style:{position:"absolute",top:0,left:Math.max(0,i),background:t?"rgba(66,119,127,0.6)":l,cursor:"pointer",height:12,width:s,zIndex:100},onMouseOver:()=>{r(!0)},onMouseOut:()=>{r(!1)},onMouseDown:d=>{u(d,e.scrollX)}}),In.default.createElement("svg",{height:a,style:{width:"100%"}},In.default.createElement("polygon",{fill:l,points:c})))}),L_=QV});var P_,O_,G_=m(()=>{"use client";we();P_=p(O(),1),O_=W((0,P_.jsx)("path",{d:"m12 8-6 6 1.41 1.41L12 10.83l4.59 4.58L18 14z"}),"ExpandLess")});var U_,eA,dy=m(()=>{"use client";we();U_=p(O(),1),eA=W((0,U_.jsx)("path",{d:"M16.59 8.59 12 13.17 7.41 8.59 6 10l6 6 6-6z"}),"ExpandMore")});var to,wa,H_,_V,V_,j_=m(()=>{to=p(Q(),1);G_();dy();wa=p(U(),1),H_=p(Y(),1),_V=(0,H_.observer)(function({model:e}){let{actuallyShowDomains:t,visibleDomainTypes:r,fillPalette:n,showDomainLegend:o}=e,i=o?O_:eA;return t&&r.length>0?to.default.createElement(wa.Paper,{elevation:3,style:{position:"absolute",top:4,right:4,zIndex:100,maxWidth:260,maxHeight:"60%",display:"flex",flexDirection:"column",opacity:.95}},to.default.createElement("div",{style:{display:"flex",alignItems:"center",justifyContent:"flex-end",padding:"2px 4px 2px 8px"}},to.default.createElement(wa.IconButton,{size:"small",title:o?"Collapse domain key":"Expand domain key",onClick:()=>{e.setShowDomainLegend(!o)}},to.default.createElement(i,{fontSize:"small"}))),o?to.default.createElement("div",{style:{overflow:"auto",padding:"0 8px 6px"}},r.map(({accession:s,name:a})=>to.default.createElement("div",{key:s,style:{display:"flex",alignItems:"center",gap:6},title:s},to.default.createElement("div",{style:{width:12,height:12,flexShrink:0,background:n[s]}}),to.default.createElement(wa.Typography,{variant:"caption",noWrap:!0},a)))):null):null}),V_=_V});function Ay(){return tA.default.createElement("div",{style:{position:"absolute",left:"50%",top:"50%"}},tA.default.createElement(rA.CircularProgress,null),tA.default.createElement(rA.Typography,null,"Loading..."))}var tA,rA,$_=m(()=>{tA=p(Q(),1),rA=p(U(),1)});function Mr(e,t){let r=(0,nA.useRef)(null);return(0,nA.useEffect)(()=>{let n=r.current?.getContext("2d");return n?(0,W_.autorun)(()=>{e(n)}):void 0},t),r}var nA,W_,Fi=m(()=>{nA=p(Q(),1),W_=p(Ls(),1)});function oA(e){let t=(0,q_.useTheme)(),r=(0,Y_.useMemo)(()=>Rc(e,t),[e,t]);return{theme:t,contrastScheme:r}}var Y_,q_,my=m(()=>{Y_=p(Q(),1),q_=p(U(),1);ho()});var dr,z_,py,kV,J_,K_=m(()=>{dr=p(Q(),1),z_=p(Y(),1),py=e=>`${Math.round(e*100)}%`,kV=(0,z_.observer)(function({model:e}){let t=e.mouseOverColumnStats;if(!t)return null;let{col:r,total:n,conservation:o,propertyConservation:i,consensusLetter:s,consensusFraction:a,gapFraction:c,distribution:l}=t,u=l.slice(0,6);return dr.default.createElement("div",null,dr.default.createElement("b",null,"Column ",r+1)," (",n," seqs)",dr.default.createElement("br",null),"Consensus: ",s||"-"," (",py(a),")",dr.default.createElement("br",null),"Conservation: ",o.toFixed(2),i===void 0?null:dr.default.createElement(dr.default.Fragment,null,dr.default.createElement("br",null),"Property conservation: ",i.toFixed(2)),dr.default.createElement("br",null),"Gaps: ",py(c),u.length>0?dr.default.createElement(dr.default.Fragment,null,dr.default.createElement("br",null),u.map(([d,A])=>dr.default.createElement("span",{key:d,style:{marginRight:8}},d," ",py(A/n)))):null)}),J_=kV});function DV({event:e,el:t,offsetX:r,offsetY:n,colWidth:o,rowHeight:i}){let{left:s,top:a}=t.getBoundingClientRect();return{col:Math.floor((e.clientX-s+r)/o),row:Math.floor((e.clientY-a+n)/i)}}function Z_({model:e,offsetX:t,offsetY:r}){let[n,o]=(0,X_.useState)();function i(u,d){let{colWidth:A,rowHeight:f}=e;return DV({event:u,el:d,offsetX:t,offsetY:r,colWidth:A,rowHeight:f})}function s({col:u,row:d}){return u>=0&&u<e.numColumns&&d>=0&&d<e.numRows}function a(u,d){let A=i(u,d),f=s(A);e.setMousePos(f?A.col:void 0,f?A.row:void 0);let g=!!e.hoveredInsertion||e.mouseOverDomains.length>0||e.showColumnStats&&!!e.mouseOverColumnStats;o(g?{x:u.clientX,y:u.clientY}:void 0)}function c(u,d){let A=i(u,d),{col:f,row:g}=A,{mouseClickCol:h,mouseClickRow:x}=e,w=f===h&&g===x,y=s(A)&&!w;e.setMouseClickPos(y?f:void 0,y?g:void 0)}function l(){e.setMousePos(),o(void 0)}return{tooltipPoint:n,onMouseMove:a,onClick:c,onMouseLeave:l}}var X_,ek=m(()=>{X_=p(Q(),1)});var Wt,tk,NV,rk,nk=m(()=>{Wt=p(Q(),1);K2();tk=p(Y(),1);Fi();my();K_();qp();sg();ek();NV=(0,tk.observer)(function({model:e,offsetX:t,offsetY:r}){let{scrollY:n,scrollX:o,colorScheme:i,blockSize:s,highResScaleFactor:a}=e,{theme:c,contrastScheme:l}=oA(i),{tooltipPoint:u,onMouseMove:d,onClick:A,onMouseLeave:f}=Z_({model:e,offsetX:t,offsetY:r}),g=Mr(y=>{let{blockSize:v,highResScaleFactor:b,actuallyShowDomains:I}=e;y.resetTransform(),y.clearRect(0,0,v*b,v*b),I&&Af({ctx:y,offsetX:t,offsetY:r,model:e}),yf({ctx:y,theme:c,offsetX:t,offsetY:r,contrastScheme:l,model:e})},[e,t,r,c,l]),{hoveredInsertion:h,mouseOverDomains:x,showColumnStats:w}=e;return Wt.default.createElement(Wt.default.Fragment,null,Wt.default.createElement("canvas",{ref:g,onMouseMove:y=>{g.current&&d(y,g.current)},onClick:y=>{g.current&&A(y,g.current)},onMouseLeave:()=>{f()},width:s*a,height:s*a,style:{position:"absolute",top:n+r,left:o+t,width:s,height:s}}),u?Wt.default.createElement(z0,{clientPoint:{x:u.x,y:u.y+15}},h?Wt.default.createElement(Wt.default.Fragment,null,"Insertion (",h.letters.length,e.sequenceType==="amino"?"aa":"bp","):"," ",h.letters.length>20?`${h.letters.slice(0,20)}...`:h.letters):Wt.default.createElement(Wt.default.Fragment,null,x.map(y=>Wt.default.createElement("div",{key:`${y.accession}-${y.start}-${y.end}`},Wt.default.createElement("b",null,y.name)," (",y.accession,") ",y.start,"-",y.end,y.description?Wt.default.createElement(Wt.default.Fragment,null,Wt.default.createElement("br",null),y.description):null)),w?Wt.default.createElement(J_,{model:e}):null)):null)}),rk=NV});var Sn,ok,LV,ik,sk=m(()=>{Sn=p(Q(),1),ok=p(Y(),1);Rf();$_();nk();LV=(0,ok.observer)(function({model:e}){let{MSA:t,verticalScrollbarWidth:r,msaFilehandle:n,height:o,msaAreaWidth:i,blocks2d:s,scrollZoom:a}=e,c=(0,Sn.useRef)(null),l=(0,Sn.useCallback)(g=>{e.doScrollX(g)},[e]),u=(0,Sn.useCallback)(g=>{e.doScrollY(g)},[e]),d=(0,Sn.useCallback)((g,h,x)=>{e.zoomToPos(g,h,x)},[e]),{onMouseDown:A,onMouseUp:f}=$s({ref:c,onScrollX:l,onScrollY:u,onZoom:d,scrollZoom:a});return Sn.default.createElement("div",{ref:c,"data-testid":"msa_canvas",onMouseDown:A,onMouseUp:f,onMouseLeave:g=>{g.preventDefault()},style:{position:"relative",height:o,width:i-r,overflow:"hidden"}},!t&&!n?null:t?s.map(([g,h])=>Sn.default.createElement(rk,{key:`${g}_${h}`,model:e,offsetX:g,offsetY:h})):Sn.default.createElement(Ay,null))}),ik=LV});var iA,ak,ck,gy=m(()=>{iA="rgba(0,128,255,0.3)",ak="rgba(255,165,0,0.2)",ck="rgba(255,165,0,0.15)"});function fk({ctx:e,model:t}){let{mouseCol:r,colWidth:n,msaAreaWidth:o,verticalScrollbarWidth:i,height:s,rowHeight:a,scrollX:c,scrollY:l,mouseRow:u,mouseClickRow:d,mouseClickCol:A,highResScaleFactor:f,referenceRowIndex:g,hoveredRowIndices:h,highlightedColumnRuns:x}=t,w=o-i;if(e.resetTransform(),e.clearRect(0,0,w*f,s*f),e.scale(f,f),g!==void 0&&(e.fillStyle=iA,e.fillRect(0,g*a+l,w,a)),h.length>0){e.fillStyle=ck;for(let y of h)e.fillRect(0,y*a+l,w,a)}if(x.length>0){e.lineWidth=2;for(let{start:y,end:v}of x){let b=y*n+c,I=(v-y+1)*n;e.fillStyle=FV,e.fillRect(b,0,I,s),e.strokeStyle=PV,e.strokeRect(b,0,I,s)}}r!==void 0&&(e.fillStyle=lk,e.fillRect(r*n+c,0,n,s)),u!==void 0&&(e.fillStyle=lk,e.fillRect(0,u*a+l,w,a)),A!==void 0&&(e.fillStyle=uk,e.fillRect(A*n+c,0,n,s)),d!==void 0&&(e.fillStyle=uk,e.fillRect(0,d*a+l,w,a))}var lk,uk,FV,PV,dk=m(()=>{gy();lk="rgba(0,0,0,0.15)",uk="rgba(128,128,0,0.2)",FV="rgba(255,140,0,0.28)",PV="rgba(210,90,0,0.95)"});var Ak,mk,pk,OV,gk,hk=m(()=>{Ak=p(Q(),1),mk=p(zt(),1),pk=p(Y(),1);Fi();dk();OV=(0,pk.observer)(function({model:e}){let{height:t,msaAreaWidth:r,verticalScrollbarWidth:n,highResScaleFactor:o}=e,i=r-n,s=Mr(a=>{(0,mk.isAlive)(e)&&fk({ctx:a,model:e})},[e]);return Ak.default.createElement("canvas",{ref:s,id:"mouseover",width:i*o,height:t*o,style:{position:"absolute",top:0,left:0,width:i,height:t,zIndex:1e3,pointerEvents:"none"}})}),gk=OV});var vl,yk,GV,xk,Ck=m(()=>{vl=p(Q(),1),yk=p(Y(),1);j_();sk();hk();GV=(0,yk.observer)(function({model:e}){return vl.default.createElement("div",{style:{position:"relative"}},vl.default.createElement(ik,{model:e}),vl.default.createElement(gk,{model:e}),vl.default.createElement(V_,{model:e}))}),xk=GV});var Bl,Ia,Ek,UV,bk,wk=m(()=>{Bl=p(Q(),1),Ia=p(U(),1),Ek=p(Y(),1),UV=(0,Ek.observer)(function({node:e,model:t,onClose:r}){return Bl.default.createElement(Ia.Menu,{anchorReference:"anchorPosition",anchorPosition:{left:e.x,top:e.y},transitionDuration:0,keepMounted:!0,open:!!e,onClose:r},Bl.default.createElement(Ia.MenuItem,{dense:!0,disabled:!0},e.name),Bl.default.createElement(Ia.MenuItem,{dense:!0,onClick:()=>{t.toggleCollapsed(e.id),r()}},t.collapsed.includes(e.id)?"Expand this node":"Collapse this node"),Bl.default.createElement(Ia.MenuItem,{dense:!0,onClick:()=>{t.showOnly===e.id?t.setShowOnly(void 0):t.setShowOnly(e.id),r()}},t.showOnly===e.id?"Disable show only this node":"Show only this node"))}),bk=UV});var Bk={};Bt(Bk,{default:()=>VV});var vn,Ik,Sk,vk,HV,VV,Tk=m(()=>{vn=p(Q(),1);Vd();ny();Ik=p(Xe(),1),Sk=p(U(),1),vk=p(Y(),1);iy();HV=(0,vk.observer)(function({info:e,model:t,nodeName:r,onClose:n}){let{treeMetadata:o,rows:i}=t,s=o[r],a=i.find(c=>c[0]===r);return vn.default.createElement(Ik.Dialog,{onClose:()=>{n()},open:!0,title:"Tree node info",maxWidth:"xl"},vn.default.createElement(Sk.DialogContent,null,vn.default.createElement(Ni,{title:"Attributes"},vn.default.createElement(wn,{attributes:{nodeName:r,...e}})),vn.default.createElement(Ni,{title:"Sequence"},a?vn.default.createElement(Il,{str:[a]}):vn.default.createElement("div",null,"Sequence not found")),s?vn.default.createElement(Ni,{title:"Extra metadata"},vn.default.createElement(wn,{attributes:s})):null))}),VV=HV});var ro,Po,Mk,jV,$V,Rk,Qk=m(()=>{ro=p(Q(),1),Po=p(U(),1),Mk=p(Y(),1),jV=(0,ro.lazy)(()=>Promise.resolve().then(()=>(Tk(),Bk))),$V=(0,Mk.observer)(function({node:e,onClose:t,model:r}){let{collapsed:n}=r,{name:o,id:i}=e,s=n.includes(i);return ro.default.createElement(Po.Menu,{anchorReference:"anchorPosition",anchorPosition:{top:e.y,left:e.x},transitionDuration:0,keepMounted:!0,open:!!e,onClose:t},ro.default.createElement(Po.MenuItem,{dense:!0,disabled:!0},o),ro.default.createElement(Po.MenuItem,{dense:!0,onClick:()=>{r.queueDialog(a=>[jV,{info:r.getRowData(o),model:r,nodeName:o,onClose:a}]),t()}},"More info..."),ro.default.createElement(Po.MenuItem,{dense:!0,onClick:()=>{r.toggleCollapsed(i),t()}},s?"Expand subtree":"Collapse subtree"),ro.default.createElement(Po.MenuItem,{dense:!0,onClick:()=>{r.drawRelativeTo(e.name),t()}},"Indicate differences from this row"),r.relativeTo?ro.default.createElement(Po.MenuItem,{dense:!0,onClick:()=>{r.drawRelativeTo(void 0),t()}},"Clear reference row"):null)}),Rk=$V});var Tl,_k=m(()=>{Tl=class{constructor(t=1/0,r=Float64Array,n=Uint32Array){let o=t!==1/0;this.ids=o?new n(t):[],this.values=o?new r(t):[],this.capacity=t,this.length=0}clear(){this.length=0}push(t,r){if(this.length===this.capacity)throw new RangeError("Queue is at capacity.");let n=this.length++;for(;n>0;){let o=n-1>>1,i=this.values[o];if(r>=i)break;this.ids[n]=this.ids[o],this.values[n]=i,n=o}this.ids[n]=t,this.values[n]=r}pop(){if(this.length===0)return;let t=this.ids,r=this.values,n=t[0],o=--this.length;if(o>0){let i=t[o],s=r[o],a=0,c=o>>1;for(;a<c;){let l=(a<<1)+1,u=l+1,d=l+(+(u<o)&+(r[u]<r[l]));if(r[d]>=s)break;t[a]=t[d],r[a]=r[d],a=d}t[a]=i,r[a]=s}return n}peek(){return this.length>0?this.ids[0]:void 0}peekValue(){return this.length>0?this.values[0]:void 0}shrink(){Array.isArray(this.ids)&&(this.ids.length=this.length),Array.isArray(this.values)&&(this.values.length=this.length)}}});function WV(e,t){let r=0,n=t.length-1;for(;r<n;){let o=r+n>>1;t[o]>e?n=o:r=o+1}return t[r]}function YV(e,t,r,n,o,i){let s=[n,o];for(;s.length;){let a=s.pop()||0,c=s.pop()||0;if(a-c<=i&&Math.floor(c/i)>=Math.floor(a/i))continue;let l=e[c],u=e[c+a>>1],d=e[a],A=l>u!=l>d?l:u<l!=u<d?u:d,f=c-1,g=a+1;for(;;){do f++;while(e[f]<A);do g--;while(e[g]>A);if(f>=g)break;qV(e,t,r,f,g)}s.push(c,g,g+1,a)}}function qV(e,t,r,n,o){let i=e[n];e[n]=e[o],e[o]=i;let s=4*n,a=4*o,c=t[s],l=t[s+1],u=t[s+2],d=t[s+3];t[s]=t[a],t[s+1]=t[a+1],t[s+2]=t[a+2],t[s+3]=t[a+3],t[a]=c,t[a+1]=l,t[a+2]=u,t[a+3]=d;let A=r[n];r[n]=r[o],r[o]=A}function zV(e,t){let r=e^t,n=65535^r,o=65535^(e|t),i=e&(t^65535),s=r|n>>1,a=r>>1^r,c=o^(o>>1^n&i>>1),l=i^(r&o>>1^i>>1);return r=s&s>>2^a&a>>2,n=s&a>>2^a&(s^a)>>2,o=c^(s&c>>2^a&l>>2),i=l^(a&c>>2^(s^a)&l>>2),s=r&r>>4^n&n>>4,a=r&n>>4^n&(r^n)>>4,c=o^(r&o>>4^n&i>>4),l=i^(n&o>>4^(r^n)&i>>4),o=c^(s&c>>8^a&l>>8),i=l^(a&c>>8^(s^a)&l>>8),o^=o>>1,i^=i>>1,r=e^t,n=i|65535^(r|o),r=(r|r<<8)&16711935,r=(r|r<<4)&252645135,r=(r|r<<2)&858993459,r=(r|r<<1)&1431655765,n=(n|n<<8)&16711935,n=(n|n<<4)&252645135,n=(n|n<<2)&858993459,n=(n|n<<1)&1431655765,((n<<1|r)>>>0)-2147483648}var kk,hy,Ml,Dk=m(()=>{_k();kk=[Int8Array,Uint8Array,Uint8ClampedArray,Int16Array,Uint16Array,Int32Array,Uint32Array,Float32Array,Float64Array],hy=3,Ml=class e{static from(t,r=0){if(r%8!==0)throw new Error("byteOffset must be 8-byte aligned.");if(!t||t.byteLength===void 0||"buffer"in t)throw new Error("Data must be an instance of ArrayBuffer or SharedArrayBuffer.");let[n,o]=new Uint8Array(t,r+0,2);if(n!==251)throw new Error("Data does not appear to be in a Flatbush format.");let i=o>>4;if(i!==hy)throw new Error(`Got v${i} data when expected v${hy}.`);let s=kk[o&15];if(!s)throw new Error("Unrecognized array type.");let[a]=new Uint16Array(t,r+2,1),[c]=new Uint32Array(t,r+4,1);return new e(c,a,s,void 0,t,r)}constructor(t,r=16,n=Float64Array,o=ArrayBuffer,i,s=0){if(t===void 0)throw new Error("Missing required argument: numItems.");if(isNaN(t)||t<=0)throw new Error(`Unexpected numItems value: ${t}.`);this.numItems=+t,this.nodeSize=Math.min(Math.max(+r,2),65535),this.byteOffset=s;let a=t,c=a;this._levelBounds=[a*4];do a=Math.ceil(a/this.nodeSize),c+=a,this._levelBounds.push(c*4);while(a!==1);this.ArrayType=n,this.IndexArrayType=c<16384?Uint16Array:Uint32Array;let l=kk.indexOf(n),u=c*4*n.BYTES_PER_ELEMENT;if(l<0)throw new Error(`Unexpected typed array class: ${n}.`);let d=n,A=this.IndexArrayType;if(i)this.data=i,this._boxes=new d(i,s+8,c*4),this._indices=new A(i,s+8+u,c),this._pos=c*4,this.minX=this._boxes[this._pos-4],this.minY=this._boxes[this._pos-3],this.maxX=this._boxes[this._pos-2],this.maxY=this._boxes[this._pos-1];else{let f=this.data=new o(8+u+c*this.IndexArrayType.BYTES_PER_ELEMENT);this._boxes=new d(f,8,c*4),this._indices=new A(f,8+u,c),this._pos=0,this.minX=1/0,this.minY=1/0,this.maxX=-1/0,this.maxY=-1/0,new Uint8Array(f,0,2).set([251,(hy<<4)+l]),new Uint16Array(f,2,1)[0]=r,new Uint32Array(f,4,1)[0]=t}this._queue=new Tl}add(t,r,n=t,o=r){let i=this._pos,s=i>>2,a=this._boxes;return this._indices[s]=s,a[i]=t,a[i+1]=r,a[i+2]=n,a[i+3]=o,this._pos=i+4,t<this.minX&&(this.minX=t),r<this.minY&&(this.minY=r),n>this.maxX&&(this.maxX=n),o>this.maxY&&(this.maxY=o),s}finish(){if(this._pos>>2!==this.numItems)throw new Error(`Added ${this._pos>>2} items when expected ${this.numItems}.`);let t=this._boxes;if(this.numItems<=this.nodeSize){t[this._pos++]=this.minX,t[this._pos++]=this.minY,t[this._pos++]=this.maxX,t[this._pos++]=this.maxY;return}let{numItems:r,minX:n,minY:o,nodeSize:i,_indices:s,_levelBounds:a}=this,c=this.maxX-n||1,l=this.maxY-o||1,u=new Int32Array(r),d=65535,A=d/c,f=d/l;for(let h=0,x=0;h<r;h++){let w=t[x++],y=t[x++],v=t[x++],b=t[x++],I=A*((w+v)/2-n)|0,S=f*((y+b)/2-o)|0;u[h]=zV(I,S)}YV(u,t,s,0,r-1,i);let g=r*4;for(let h=0,x=0;h<a.length-1;h++){let w=a[h];for(;x<w;){let y=x,v=t[x++],b=t[x++],I=t[x++],S=t[x++];for(let B=1;B<i&&x<w;B++)v=Math.min(v,t[x++]),b=Math.min(b,t[x++]),I=Math.max(I,t[x++]),S=Math.max(S,t[x++]);s[g>>2]=y,t[g++]=v,t[g++]=b,t[g++]=I,t[g++]=S}}this._pos=g}search(t,r,n,o,i){if(this._pos!==this._boxes.length)throw new Error("Data not yet indexed - call index.finish().");let{_boxes:s,_levelBounds:a,_indices:c,nodeSize:l}=this,u=this.numItems*4,d=s.length-4,A=a.length-1,f=[],g=[],h=!1;for(;d!==void 0;){let x=Math.min(d+l*4,a[A]),w=d>=u;if(h)this._collectContained(d,x,A,u,g,i);else for(let y=d;y<x;y+=4){let v=s[y];if(n<v)continue;let b=s[y+1];if(o<b)continue;let I=s[y+2];if(t>I)continue;let S=s[y+3];if(r>S)continue;let B=c[y>>2]|0;if(w){let R=+(t<=v&&r<=b&&n>=I&&o>=S);f.push(B|R,A-1)}else(i===void 0||i(B,v,b,I,S))&&g.push(B)}A=f.pop(),d=f.pop(),d!==void 0&&(h=(d&1)===1,d&=-2)}return g}_collectContained(t,r,n,o,i,s){let a=this._boxes,c=this._indices,l=t;for(let d=n;d>0;d--)l=c[l>>2];let u=Math.min(l+(r-t)*this.nodeSize**n,o);if(s===void 0)for(;l<u;l+=4)i.push(c[l>>2]|0);else for(;l<u;l+=4){let d=c[l>>2]|0;s(d,a[l],a[l+1],a[l+2],a[l+3])&&i.push(d)}}neighbors(t,r,n=1/0,o=1/0,i){if(this._pos!==this._boxes.length)throw new Error("Data not yet indexed - call index.finish().");let{_boxes:s,_levelBounds:a,_indices:c,_queue:l,nodeSize:u}=this,d=this.numItems*4,A=u*4,f=[],g=o*o,h=n===1,x=g;for(l.push(s.length-4<<1,0);l.length;){let w=l.ids[0];if(w&1){if(l.pop(),f.push(w>>1),f.length===n)break;continue}l.pop();let y=w>>1,v=y<d,b=Math.min(y+A,WV(y,a));for(let I=y;I<b;I+=4){let S=s[I],B=s[I+1],R=s[I+2],D=s[I+3],L=Math.max(Math.max(S-t,t-R),0),P=Math.max(Math.max(B-r,r-D),0),C=L*L+P*P;if(C>x)continue;let M=c[I>>2]|0;v?(i===void 0||i(M))&&(l.push(M<<1|1,C),h&&C<x&&(x=C)):l.push(M<<1,C)}}return l.clear(),f}}});var sA,Nk=m(()=>{Dk();sA=class{flatbush=null;entries=[];clear(){this.flatbush=null,this.entries=[]}insert(t){this.entries.push(t)}finish(){if(this.entries.length===0)this.flatbush=null;else{this.flatbush=new Ml(this.entries.length);for(let t of this.entries)this.flatbush.add(t.minX,t.minY,t.maxX,t.maxY);this.flatbush.finish()}}search(t){return this.flatbush?.search(t.minX,t.minY,t.maxX,t.maxY).map(r=>this.entries[r])??[]}}});function Lk({model:e,offsetY:t}){let r=(0,aA.useRef)(null);r.current??=new sA;let n=r.current,[o,i]=(0,aA.useState)();function s(l){let u=l.nativeEvent.offsetX,d=l.nativeEvent.offsetY+t,A=n.search({minX:u,maxX:u+1,minY:d,maxY:d+1});return A.find(f=>!f.branch)??A[0]}function a(l){let u=s(l);i(u?{...u,clientX:l.clientX,clientY:l.clientY}:void 0),e.setHoveredTreeNode(u?.id),e.setMousePos(void 0,u&&!u.branch?e.rowNamesSet.get(u.name):void 0)}function c(){i(void 0),e.setHoveredTreeNode(void 0),e.setMousePos(void 0,void 0)}return{clickMap:n,hovered:o,hitTest:s,onMouseMove:a,onMouseLeave:c}}var aA,Fk=m(()=>{aA=p(Q(),1);Nk()});var Wr,Pk,Ok,JV,KV,Gk,Uk=m(()=>{Wr=p(Q(),1);He();Pk=p(U(),1),Ok=p(Y(),1);Fi();wk();Qk();vf();Fk();JV=Z()(e=>({tooltip:{position:"fixed",pointerEvents:"none",zIndex:1e4,backgroundColor:e.palette.grey[700],color:e.palette.common.white,padding:"4px 8px",borderRadius:4,fontSize:12,whiteSpace:"nowrap",maxWidth:300,overflow:"hidden",textOverflow:"ellipsis"},hover:{position:"absolute",pointerEvents:"none",zIndex:100,background:"rgba(0,0,0,0.1)"}})),KV=(0,Ok.observer)(function({model:e,offsetY:t}){let{classes:r}=JV(),n=(0,Pk.useTheme)(),[o,i]=(0,Wr.useState)(),[s,a]=(0,Wr.useState)(),{clickMap:c,hovered:l,hitTest:u,onMouseMove:d,onMouseLeave:A}=Lk({model:e,offsetY:t}),{scrollY:f,treeAreaWidth:g,blockSize:h,highResScaleFactor:x}=e,w=g+If,y=h,v=Mr(I=>{I.resetTransform(),I.clearRect(0,0,w*x,y*x),Sf({ctx:I,model:e,offsetY:t,clickMap:c,theme:n})},[e,c,t,n]),b={width:w,height:y,top:f+t,left:0,position:"absolute"};return Wr.default.createElement(Wr.default.Fragment,null,o?Wr.default.createElement(bk,{node:o,model:e,onClose:()=>{i(void 0)}}):null,s?Wr.default.createElement(Rk,{node:s,model:e,onClose:()=>{a(void 0)}}):null,Wr.default.createElement("canvas",{ref:v,width:w*x,height:y*x,style:{...b,cursor:l?"pointer":"default"},onMouseMove:I=>{d(I)},onMouseLeave:()=>{A()},onClick:I=>{let S=u(I);if(S){let B={x:I.clientX,y:I.clientY,id:S.id,name:S.name};S.branch?i(B):a(B)}}}),l&&!l.branch?Wr.default.createElement("div",{className:r.hover,style:{left:l.minX,top:l.minY+f,width:l.maxX-l.minX,height:l.maxY-l.minY}}):null,l?Wr.default.createElement("div",{className:r.tooltip,style:{left:l.clientX+12,top:l.clientY+12}},l.name):null)}),Gk=KV});var Oo,Hk,Vk,XV,jk,$k=m(()=>{Oo=p(Q(),1),Hk=p(zt(),1),Vk=p(Y(),1);Fi();Rf();gy();Uk();vf();XV=(0,Vk.observer)(function({model:e}){let t=(0,Oo.useRef)(null),{treeWidth:r,height:n,blocksY:o,treeAreaWidth:i}=e,s=(0,Oo.useCallback)(u=>{e.doScrollY(u)},[e]),{onMouseDown:a,onMouseUp:c}=$s({ref:t,onScrollY:s}),l=Mr(u=>{if((0,Hk.isAlive)(e)){let{rowHeight:d,treeAreaWidth:A,height:f,scrollY:g,mouseRow:h,referenceRowIndex:x,hoveredRowIndices:w}=e;u.resetTransform(),u.clearRect(0,0,A,f);let y=v=>{u.fillRect(0,v*d+g,A,d)};x!==void 0&&(u.fillStyle=iA,y(x)),u.fillStyle=ak;for(let v of w)y(v);h!==void 0&&h!==x&&!w.includes(h)&&y(h)}},[e]);return Oo.default.createElement("div",{ref:t,onMouseDown:a,onMouseUp:c,onMouseLeave:u=>{u.preventDefault()},style:{height:n,position:"relative",width:r+If}},o.map(u=>Oo.default.createElement(Gk,{key:u,model:e,offsetY:u})),Oo.default.createElement("canvas",{ref:l,width:i,height:n,style:{position:"absolute",top:0,left:0,width:i,height:n,zIndex:1e3,pointerEvents:"none"}}))}),jk=XV});var yy,Wk,ZV,Yk,qk=m(()=>{yy=p(Q(),1),Wk=p(Y(),1);$k();ZV=(0,Wk.observer)(function({model:e}){let{treeAreaWidth:t}=e;return yy.default.createElement("div",{style:{overflow:"hidden",flexShrink:0,width:t}},yy.default.createElement(jk,{model:e}))}),Yk=ZV});var zk,Jk,ej,Kk,Xk=m(()=>{zk=p(Q(),1),Jk=p(Y(),1),ej=(0,Jk.observer)(({model:e})=>{let{treeAreaWidth:t}=e;return zk.default.createElement("div",{style:{flexShrink:0,width:t}})}),Kk=ej});var ue,Pi,tj,rj,nj,oj,ij,sj,Zk,eD=m(()=>{ue=p(Q(),1),Pi=p(Y(),1);Ig();DS();PS();D_();F_();Ck();qk();Xk();tj=(0,Pi.observer)(function({model:e}){let{showHorizontalScrollbar:t}=e;return ue.default.createElement("div",{style:{display:"flex"}},ue.default.createElement(Kk,{model:e}),t?ue.default.createElement(L_,{model:e}):null)}),rj=(0,Pi.observer)(function({model:e}){let{mouseCol:t,mouseClickCol:r,colWidth:n,scrollX:o,treeAreaWidth:i,resizeHandleWidth:s,totalTrackAreaHeight:a,msaAreaWidth:c,verticalScrollbarWidth:l}=e,u=i+s,d=c-l;return ue.default.createElement("div",{style:{position:"absolute",left:u,top:0,width:d,height:a,overflow:"hidden",pointerEvents:"none"}},t!==void 0?ue.default.createElement("div",{style:{position:"absolute",left:t*n+o,top:0,width:n,height:a,backgroundColor:"rgba(0,0,0,0.15)",zIndex:100}}):null,r!==void 0?ue.default.createElement("div",{style:{position:"absolute",left:r*n+o,top:0,width:n,height:a,backgroundColor:"rgba(128,128,0,0.2)",zIndex:100}}):null)}),nj=(0,Pi.observer)(function({model:e}){let{turnedOnTracks:t}=e;return t.length===0?null:ue.default.createElement("div",{style:{position:"relative"}},ue.default.createElement(rj,{model:e}),t.map(r=>ue.default.createElement(kS,{key:r.model.id,model:e,track:r})))}),oj=(0,Pi.observer)(function({model:e}){let{showVerticalScrollbar:t}=e;return ue.default.createElement("div",{style:{display:"flex"}},ue.default.createElement(Yk,{model:e}),ue.default.createElement(nS,{model:e}),ue.default.createElement(xk,{model:e}),t?ue.default.createElement(FS,{model:e}):null)}),ij=(0,Pi.observer)(function({model:e}){return ue.default.createElement("div",{style:{position:"relative"}},ue.default.createElement(tj,{model:e}),ue.default.createElement(nj,{model:e}),ue.default.createElement(oj,{model:e}))}),sj=(0,Pi.observer)(function({model:e}){let{height:t,viewInitialized:r,DialogComponent:n,DialogProps:o}=e;return ue.default.createElement("div",null,r?ue.default.createElement(ue.default.Fragment,null,ue.default.createElement("div",{style:{height:t,overflow:"hidden"}},ue.default.createElement(k_,{model:e}),ue.default.createElement(ij,{model:e})),ue.default.createElement(oS,{model:e}),n?ue.default.createElement(ue.Suspense,{fallback:null},ue.default.createElement(n,{...o})):null):null)}),Zk=sj});var tD,rD,nD,oD=m(()=>{tD=`CLUSTAL O(1.2.3) multiple sequence alignment
 UniProt/Swiss-Prot|P26898|IL2RA_SHEEP      MEPSLLMWRFFVFIVVPGCVTEACHDDPPSLRNA----------MFKVLRYE----VGTM
 UniProt/Swiss-Prot|P01590|IL2RA_MOUSE      MEPRLLMLGFLSLTIVPSCRAELCLYDPPEVPNA----------TFKALSYK----NGTI
 UniProt/Swiss-Prot|P41690|IL2RA_FELCA      MEPSLLLWGILTFVVVHGHVTELCDENPPDIQHA----------TFKALTYK----TGTM
@@ -59,7 +57,7 @@ UniProt/Swiss-Prot|Q8BZM1|GLMN_MOUSE       PLPLRSLLFLQLPLLGVGLNP----------------
 UniProt/Swiss-Prot|P36835|IL2_CAPHI        -----------LLGVGLNPKFLTP------------------------------------
 UniProt/Swiss-Prot|Q7JFM4|IL2_AOTVO        MLKPPLPLRSLLFLQLPLLGVGLNPKFLTPSGNEDIGGKPGTGGDFFLTSTPAGTLDVST
 UniProt/Swiss-Prot|Q29416|IL2_CANFA        --------------LFLQLSLLG-------------------------------------
-`,Wk=`CLUSTAL O(1.2.4) multiple sequence alignment
+`,rD=`CLUSTAL O(1.2.4) multiple sequence alignment
 
 
 sp|P69905|HBA_HUMAN       MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG	60
@@ -75,18 +73,18 @@ sp|P13786|HBAZ_CAPHI      SKVVAAVGDAVKSIDNVTSALSKLSELHAYVLRVDPVNFKFLSHCLLVTLASHF
 sp|P69905|HBA_HUMAN       AVHASLDKFLASVSTVLTSKYR	142
 sp|P01942|HBA_MOUSE       AVHASLDKFLASVSTVLTSKYR	142
 sp|P13786|HBAZ_CAPHI      DAHAAWDKFLSIVSGVLTEKYR	142
-                           .**: ****: ** ***.***`,Yk="(((UniProt/Swiss-Prot|P26898|IL2RA_SHEEP:0.24036,(UniProt/Swiss-Prot|P41690|IL2RA_FELCA:0.17737,(UniProt/Swiss-Prot|P01589|IL2RA_HUMAN:0.03906,UniProt/Swiss-Prot|Q5MNY4|IL2RA_MACMU:0.03787):0.13033):0.04964):0.02189,UniProt/Swiss-Prot|P01590|IL2RA_MOUSE:0.23072):0.06814,(((UniProt/Swiss-Prot|Q95118|IL2RG_BOVIN:0.09600,UniProt/Swiss-Prot|P40321|IL2RG_CANFA:0.09845):0.25333,UniProt/Swiss-Prot|Q29416|IL2_CANFA:-0.35055):0.10231,(UniProt/Swiss-Prot|P26896|IL2RB_RAT:0.33631,UniProt/Swiss-Prot|Q7JFM4|IL2_AOTVO:-0.33631):0.10166):0.01607,(UniProt/Swiss-Prot|Q8BZM1|GLMN_MOUSE:0.32378,UniProt/Swiss-Prot|P36835|IL2_CAPHI:-0.32378):0.09999)"});async function Kd(e,t,r,n){e.setError(void 0),t&&e.setMSAFilehandle(t),r&&e.setTreeFilehandle(r),n&&e.setGFFFilehandle(n)}var fy=m(()=>{});function kn({onClick:e,model:t,children:r}){return qt.default.createElement("li",null,qt.default.createElement(Xd.Link,{onClick:n=>{t.setError(void 0),n.preventDefault(),e()},href:"#"},qt.default.createElement(Xd.Typography,{component:"span"},r)))}var qt,Xd,zk,Vo,PV,Jk,Kk=m(()=>{qt=p(Q(),1),Xd=p(U(),1),zk=p(W(),1);qk();fy();Vo="https://jbrowse.org/genomes/multiple_sequence_alignments",PV=(0,zk.observer)(function({model:e}){function t({msa:r,tree:n,gff:o}){(async()=>{try{await Kd(e,r?{uri:r,locationType:"UriLocation"}:void 0,n?{uri:n,locationType:"UriLocation"}:void 0,o?{uri:o,locationType:"UriLocation"}:void 0)}catch(i){console.error(i),e.setError(i)}})()}return qt.default.createElement("ul",null,qt.default.createElement(kn,{model:e,onClick:()=>{t({tree:"https://jbrowse.org/genomes/newicktrees/sarscov2phylo.pub.ft.nh"})}},"230k COVID-19 samples (tree only)"),qt.default.createElement(kn,{model:e,onClick:()=>{e.setData({msa:$k,tree:Yk})}},"Small protein MSA+tree"),qt.default.createElement(kn,{model:e,onClick:()=>{e.setData({msa:Wk})}},"Small MSA only"),qt.default.createElement(kn,{model:e,onClick:()=>{t({msa:`${Vo}/pfam-cov2.stock`})}},"PFAM SARS-CoV2 multi-stockholm"),qt.default.createElement(kn,{model:e,onClick:()=>{t({msa:`${Vo}/pfam-cov2.stock`,gff:`${Vo}/pfam-cov2-domains.gff`})}},"PFAM SARS-CoV2 multi-stockholm w/ domains loaded"),qt.default.createElement(kn,{model:e,onClick:()=>{t({msa:`${Vo}/Lysine.stock`})}},"Lysine stockholm file"),qt.default.createElement(kn,{model:e,onClick:()=>{t({msa:`${Vo}/PF01601_full.txt`})}},"PF01601 stockholm file (SARS-CoV2 spike protein)"),qt.default.createElement(kn,{model:e,onClick:()=>{t({msa:`${Vo}/europe_covid.fa`})}},"Europe COVID full genomes (LR883044.1 and 199 other sequences)"),qt.default.createElement(kn,{model:e,onClick:()=>{t({msa:`${Vo}/rhv_test-only.aligned_with_mafft_auto.fa`,tree:`${Vo}/rhv_test-only.aligned_with_mafft_auto.nh`})}},"MAFFT+VeryFastTree(17.9k samples)"),qt.default.createElement(kn,{model:e,onClick:()=>{t({msa:"https://jbrowse.org/demos/ttc39a.mfa"})}},"Human BLAST results mfa"))}),Jk=PV});var Se,va,tn,Xk,FV,Zk,eD=m(()=>{Se=p(Q(),1),va=p(Ze(),1),tn=p(U(),1),Xk=p(W(),1);Kk();fy();FV=(0,Xk.observer)(function({model:e}){let[t,r]=(0,Se.useState)(),[n,o]=(0,Se.useState)(),[i,s]=(0,Se.useState)(),{error:a}=e;return Se.default.createElement(tn.Container,null,Se.default.createElement("div",{style:{width:"50%"}},a?Se.default.createElement(va.ErrorMessage,{error:a}):null,Se.default.createElement(tn.Typography,null,"Open an MSA file (stockholm or clustal format) and/or a tree file (newick format)."),Se.default.createElement(tn.Typography,{color:"error"},"Note: you can open up just an MSA or just a tree, both are not required. Some MSA files e.g. stockholm format have an embedded tree also and this is fine, and opening a separate tree file is not required.")),Se.default.createElement("div",{style:{display:"flex",justifyContent:"center",alignItems:"center",gap:40}},Se.default.createElement("div",null,Se.default.createElement("div",null,Se.default.createElement(tn.Typography,null,"MSA file or URL"),Se.default.createElement(va.FileSelector,{location:t,setLocation:r})),Se.default.createElement("div",null,Se.default.createElement(tn.Typography,null,"Tree file or URL"),Se.default.createElement(va.FileSelector,{location:n,setLocation:o})),Se.default.createElement("div",null,Se.default.createElement(tn.Typography,null,"InterProScan GFF file or URL (optional)"),Se.default.createElement(va.FileSelector,{location:i,setLocation:s}))),Se.default.createElement("div",null,Se.default.createElement(tn.Button,{onClick:()=>{(async()=>{try{await Kd(e,t,n,i)}catch(c){console.error(c),e.setError(c)}})()},variant:"contained",color:"primary",disabled:!t&&!n},"Open")),Se.default.createElement("div",null,Se.default.createElement(tn.Typography,null,"Examples"),Se.default.createElement(Jk,{model:e}))))}),Zk=FV});var pt,rD,vl,Zd,tD,OV,GV,eA,dy=m(()=>{pt=p(Q(),1),rD=p(Ze(),1);dg();vl=p(U(),1),Zd=p(W(),1);jk();eD();tD=(0,Zd.observer)(function({model:e}){let{status:t}=e;return pt.default.createElement("div",{style:{display:"flex",alignItems:"center",gap:12,padding:20}},pt.default.createElement("svg",{width:"24",height:"24",viewBox:"0 0 24 24",xmlns:"http://www.w3.org/2000/svg"},pt.default.createElement("style",null,"@keyframes spinner { to { transform: rotate(360deg); } }"),pt.default.createElement("circle",{cx:"12",cy:"12",r:"10",stroke:"#ccc",strokeWidth:"3",fill:"none"}),pt.default.createElement("path",{d:"M12 2a10 10 0 0 1 10 10",stroke:"#1976d2",strokeWidth:"3",fill:"none",strokeLinecap:"round",style:{animation:"spinner 1s linear infinite",transformOrigin:"center"}})),pt.default.createElement(vl.Typography,{variant:"h6"},t?.msg??"Loading..."),t?.onCancel?pt.default.createElement(vl.Button,{variant:"outlined",size:"small",onClick:()=>t.onCancel?.()},"Cancel"):null)}),OV=(0,Zd.observer)(function({model:e,error:t}){return pt.default.createElement("div",null,pt.default.createElement(rD.ErrorMessage,{error:t}),pt.default.createElement(vl.Button,{variant:"contained",color:"primary",onClick:()=>{e.reset()}},"Return to import form"))}),GV=(0,Zd.observer)(function({model:e}){let{isLoading:t,dataInitialized:r,msaFilehandle:n,treeFilehandle:o}=e,i=!!(n||o);return pt.default.createElement("div",null,pt.default.createElement(Hs,{FallbackComponent:s=>pt.default.createElement(OV,{model:e,error:s.error})},r?t?pt.default.createElement(tD,{model:e}):pt.default.createElement(Vk,{model:e}):i||t?pt.default.createElement(tD,{model:e}):pt.default.createElement(Zk,{model:e})))}),eA=GV});var oD=K((PAe,nD)=>{nD.exports=JBrowseExports["@jbrowse/core/ui/theme"]});var Ay=K((FAe,iD)=>{iD.exports=JBrowseExports["@jbrowse/core/util/io"]});var aD=K((OAe,sD)=>{sD.exports=JBrowseExports["@jbrowse/core/util/types/mst"]});function my({mapSize:e,blockSize:t,viewportPos:r,viewportSize:n}){let o=Math.max(0,Math.min(r,e-n)),i=Math.floor(o/t),s=Math.floor((o+n-1)/t),a=[];for(let c=i;c<=s;c++)a.push(c*t);return a}var cD=m(()=>{});function AD(e,t){let r=e.total(t),n=G=>e.count(t,G),o=n("W"),i=n("L"),s=n("V"),a=n("I"),c=n("M"),l=n("A"),u=n("F"),d=n("C"),A=n("H"),f=n("P"),g=n("R"),h=n("K"),y=n("Q"),E=n("E"),x=n("D"),S=n("T"),w=n("S"),I=n("G"),v=n("Y"),B=n("N"),R=o+i+s+a+c+l+u+d+A+f+v,D=h+g,L=y+E,F=E+x,C=S+w,M=G=>G/r,k={};return M(R)>.6&&(k.W=jo,k.L=jo,k.V=jo,k.A=jo,k.I=jo,k.M=jo,k.F=jo,k.C=jo),(M(D)>.6||M(h)>.8||M(g)>.8||M(y)>.8)&&(k.K=lD,k.R=lD),(M(D)>.6||M(L)>.5||M(E)>.8||M(y)>.8||M(x)>.8)&&(k.E=UV),(M(D)>.6||M(F)>.5||M(h)>.8||M(g)>.8||M(y)>.8)&&(k.D=HV),(M(B)>.5||M(v)>.85)&&(k.N=uD),(M(D)>.6||M(L)>.6||M(y)>.85||M(E)>.85||M(h)>.85||M(g)>.85)&&(k.Q=uD),(M(R)>.6||M(C)>.5||M(w)>.85||M(S)>.85)&&(k.S=fD,k.T=fD),M(d)>.85&&(k.C=VV),I>0&&(k.G=jV),f>0&&(k.P=$V),(M(R)>.6||M(o)>.85||M(v)>.85||M(l)>.85||M(d)>.85||M(f)>.85||M(y)>.85||M(u)>.85||M(A)>.85||M(a)>.85||M(i)>.85||M(c)>.85||M(s)>.85)&&(k.H=dD,k.Y=dD),k}var jo,lD,UV,HV,uD,fD,VV,jV,$V,dD,mD=m(()=>{jo="rgb(128,179,230)",lD="#d88",UV="rgb(192, 72, 192)",HV="rgb(204, 77, 204)",uD="#8f8",fD="rgb(26,204,26)",VV="rgb(240, 128, 128)",jV="rgb(240, 144, 72)",$V="rgb(204, 204, 0)",dD="rgb(26, 179, 179)"});function tA(e){return e<128?Ba[e]:30}function pD(e){return e===27||e===28}function gD(e){return Oi[e]}function hD(e){return tA(e.charCodeAt(0))}function xD(e){let t=e.reduce((n,o)=>Math.max(n,o.length),0),r=new py(t);for(let n of e)r.addRow(n);return r}var Ba,Oi,py,yD,gy=m(()=>{Ba=new Uint8Array(128).fill(30);for(let e=65;e<=90;e++)Ba[e]=e-65+1;for(let e=97;e<=122;e++)Ba[e]=e-97+1;Ba[45]=27;Ba[46]=28;Ba[42]=29;Oi=Array.from({length:32},(e,t)=>t>=1&&t<=26?String.fromCharCode(65+t-1):"");Oi[27]="-";Oi[28]=".";Oi[29]="*";Oi[30]="?";py=class{numColumns;counts;totals;slotTotals=new Uint32Array(32);constructor(t){this.numColumns=t,this.counts=new Uint32Array(t*32),this.totals=new Uint32Array(t)}addRow(t){let{counts:r,totals:n,slotTotals:o}=this,i=Math.min(t.length,this.numColumns);for(let s=0;s<i;s++){let a=tA(t.charCodeAt(s));r[s*32+a]++,n[s]++,o[a]++}}add(t,r){let n=tA(r.charCodeAt(0));this.counts[t*32+n]++,this.totals[t]++,this.slotTotals[n]++}total(t){return this.totals[t]??0}count(t,r){return this.counts[t*32+tA(r.charCodeAt(0))]??0}gapCount(t){let r=t*32;return(this.counts[r+27]??0)+(this.counts[r+28]??0)}forEachResidue(t,r){let{counts:n}=this,o=t*32;for(let i=1;i<32;i++){let s=n[o+i];s>0&&!pD(i)&&r(i,s)}}residueEntries(t){let r=[];return this.forEachResidue(t,(n,o)=>{r.push([Oi[n],o])}),r}get lettersPresent(){let t=new Set;for(let r=1;r<32;r++)this.slotTotals[r]>0&&!pD(r)&&t.add(Oi[r]);return t}};yD=32});var Bl,hy,WV,YV,yy,CD=m(()=>{Bl=p(Q(),1),hy=p(W(),1);Pi();pg();df();WV=(0,hy.observer)(function({model:e,track:t,offsetX:r,trackHeight:n}){let{blockSize:o,scrollX:i,highResScaleFactor:s}=e,a=Dr(c=>{let{blockSize:l,colWidth:u,highResScaleFactor:d}=e;c.resetTransform(),c.scale(d,d),c.clearRect(0,0,l,n),c.translate(-r,0),eg({ctx:c,values:tg(e,t.model.id),color:t.model.barColor??"gray",colWidth:u,trackHeight:n,offsetX:r,blockSize:l})},[e,t,r,n]);return Bl.default.createElement("canvas",{ref:a,height:n*s,width:o*s,style:{position:"absolute",left:i+r,width:o,height:n}})}),YV=(0,hy.observer)(function({model:e,track:t}){let{blocksX:r,msaAreaWidth:n}=e,o=t.model.height;return Bl.default.createElement("div",{style:{position:"relative",height:o,width:n,overflow:"hidden"}},r.map(i=>Bl.default.createElement(WV,{key:i,model:e,track:t,offsetX:i,trackHeight:o})),Bl.default.createElement(WI,{model:e}))}),yy=YV});var rA,xy,qV,zV,bD,ED=m(()=>{rA=p(Q(),1),xy=p(W(),1);Gs();Pi();sy();df();qV=(0,xy.observer)(function({track:e,model:t,offsetX:r}){let{blockSize:n,scrollX:o,colorScheme:i,rowHeight:s,highResScaleFactor:a}=t,{model:{customColorScheme:c,data:l}}=e,u=c??i,{theme:d,contrastScheme:A}=Yd(u),f=Dr(g=>{let{blockSize:h,bgColor:y,colWidth:E,fontSize:x,rowHeight:S,highResScaleFactor:w}=t;g.resetTransform(),g.scale(w,w),g.clearRect(0,0,h,S),g.translate(-r,0),g.textAlign="center",bn(g,x),rg({ctx:g,data:l,colorScheme:u,contrastScheme:A,bgColor:y,textColor:d.palette.text.primary,colWidth:E,rowHeight:S,offsetX:r,blockSize:h})},[t,r,d,A,u,l]);return rA.default.createElement("canvas",{ref:f,height:s*a,width:n*a,style:{position:"absolute",left:o+r,width:n,height:s}})}),zV=(0,xy.observer)(function({track:e,model:t}){let{blocksX:r,msaAreaWidth:n,rowHeight:o}=t;return e.model.data?rA.default.createElement("div",{style:{position:"relative",height:o,width:n,overflow:"hidden"}},r.map(i=>rA.default.createElement(qV,{key:i,track:e,model:t,offsetX:i}))):null}),bD=zV});var JV,Cy,wD=m(()=>{JV=[["#F8766D"],["#F8766D","#00BFC4"],["#F8766D","#00BA38","#619CFF"],["#F8766D","#7CAE00","#00BFC4","#C77CFF"],["#F8766D","#A3A500","#00BF7D","#00B0F6","#E76BF3"],["#F8766D","#B79F00","#00BA38","#00BFC4","#619CFF","#F564E3"],["#F8766D","#C49A00","#53B400","#00C094","#00B6EB","#A58AFF","#FB61D7"],["#F8766D","#CD9600","#7CAE00","#00BE67","#00BFC4","#00A9FF","#C77CFF","#FF61CC"]],Cy=JV});function ID(e){let t=e.length;if(t<=Cy.length){let r=Cy[t-1];return Object.fromEntries(e.map((n,o)=>[n,r[o]]))}return Object.fromEntries(e.map((r,n)=>[r,st({h:n*360/t,s:60,l:60}).toHex()]))}var SD=m(()=>{vc();wD()});function vD(e){let t=new Map(e.map(n=>[n.id,{id:`${n.id}`,name:`${n.id}`,parent:n.parent!==void 0?`${n.parent}`:void 0,children:[]}])),r;for(let n of e){let o=t.get(n.id),i=n.parent!==void 0?t.get(n.parent):void 0;i?i.children.push(o):r??=o}if(r===void 0)throw new Error("could not build tree from flat node list: no root found (input was empty or contains a parent cycle)");return r}var BD=m(()=>{});function TD(e,t){by||(by=document.createElement("canvas"));let r=by.getContext("2d");if(!r)throw new Error("no canvas context");return bn(r,t),r.measureText(e).width}var by,MD=m(()=>{Gs()});function RD(){return Dn.types.model({tree:Dn.types.maybe(Dn.types.string),msa:Dn.types.maybe(Dn.types.string),treeMetadata:Dn.types.maybe(Dn.types.string),gff:Dn.types.maybe(Dn.types.string)}).actions(e=>({setTree(t){e.tree=t},setMSA(t){e.msa=t},setTreeMetadata(t){e.treeMetadata=t},setGFF(t){e.gff=t}})).postProcessSnapshot(e=>{let{tree:t,msa:r,treeMetadata:n,gff:o}=e,i=5e4;return{tree:t&&t.length>i?void 0:t,msa:r&&r.length>i?void 0:r,treeMetadata:n&&n.length>i?void 0:n,gff:o&&o.length>i?void 0:o}})}var Dn,QD=m(()=>{Dn=p(Kt(),1)});function kD(){return _D.types.model("DialogQueueSessionMixin",{}).volatile(()=>({queueOfDialogs:[]})).views(e=>({get DialogComponent(){return e.queueOfDialogs[0]?.[0]},get DialogProps(){return e.queueOfDialogs[0]?.[1]}})).actions(e=>({removeActiveDialog(){e.queueOfDialogs=e.queueOfDialogs.slice(1)},queueDialog(t){let[r,n]=t(()=>{this.removeActiveDialog()});e.queueOfDialogs=[...e.queueOfDialogs,[r,n]]}}))}var _D,DD=m(()=>{_D=p(Kt(),1)});function he(e,t){return typeof nA.types.stripDefault=="function"?nA.types.stripDefault(e,t):nA.types.optional(e,t)}var nA,oA=m(()=>{nA=p(Kt(),1)});function ND(){return Gi.types.model({bgColor:he(Gi.types.boolean,qw),colorSchemeName:he(Gi.types.string,nf),showColumnStats:he(Gi.types.boolean,zw),msaFormat:Gi.types.maybe(Gi.types.enumeration("MSAFormat",KV))}).actions(e=>({setColorSchemeName(t){e.colorSchemeName=t},setBgColor(t){e.bgColor=t},setShowColumnStats(t){e.showColumnStats=t},setMSAFormat(t){e.msaFormat=t}}))}var Gi,KV,LD=m(()=>{Gi=p(Kt(),1);Ic();oA();KV=["stockholm","a3m","fasta","emf","clustal"]});function PD(){return Nn.types.model({drawLabels:he(Nn.types.boolean,Jw),labelsAlignRight:he(Nn.types.boolean,Kw),treeAreaWidth:he(Nn.types.number,Xw),treeWidth:he(Nn.types.number,Zw),showBranchLen:he(Nn.types.boolean,eI),drawTree:he(Nn.types.boolean,tI),drawNodeBubbles:he(Nn.types.boolean,rI),autoTreeAreaWidth:he(Nn.types.boolean,!1)}).actions(e=>({setTreeAreaWidth(t){e.treeAreaWidth=Math.round(t)},setTreeWidth(t){e.treeWidth=Math.round(t)},setLabelsAlignRight(t){e.labelsAlignRight=t},setDrawTree(t){e.drawTree=t},setAutoTreeAreaWidth(t){e.autoTreeAreaWidth=t},setShowBranchLen(t){e.showBranchLen=t},setDrawNodeBubbles(t){e.drawNodeBubbles=t},setDrawLabels(t){e.drawLabels=t}}))}var Nn,FD=m(()=>{Nn=p(Kt(),1);Ic();oA()});function Ey(e,t){return GD.get(e.toUpperCase())?.get(t.toUpperCase())??-4}function ZV(e,t){if(e.length!==t.length)throw new Error("Sequences must have the same length (aligned)");let r=0,n=0,o=0,i=0;for(let l=0;l<e.length;l++){let u=e[l],d=t[l];if(u==="-"&&d==="-")continue;if(u==="-"||d==="-"){n++;continue}let A=Ey(u,d);o+=A,i+=Math.max(Ey(u,u),Ey(d,d)),u.toUpperCase()===d.toUpperCase()?r++:n++}if(r+n===0||i<=0)return 1;let a=o/i,c=Math.max(.01,Math.min(1,a));return-Math.log(c)}function ej(e){let t=e.length,r=[];for(let n=0;n<t;n++){r[n]=[];for(let o=0;o<t;o++)n===o?r[n][o]=0:o<n?r[n][o]=r[o][n]:r[n][o]=ZV(e[n][1],e[o][1])}return r}function tj(e,t){let r=e.length;if(r<2)return{name:t[0]};if(r===2){let a=e[0][1];return{left:{name:t[0]},right:{name:t[1]},leftLength:a/2,rightLength:a/2}}let n=[];for(let a=0;a<r;a++)n[a]=[...e[a]];let o=t.map(a=>({name:a})),i=r;for(;i>2;){let a=[];for(let x=0;x<o.length;x++)o[x]!==void 0&&a.push(x);let c=new Map;for(let x of a){let S=0;for(let w of a)x!==w&&(S+=n[x][w]);c.set(x,S)}let l=1/0,u=-1,d=-1;for(let x=0;x<a.length;x++)for(let S=x+1;S<a.length;S++){let w=a[x],I=a[S],v=(i-2)*n[w][I]-c.get(w)-c.get(I);v<l&&(l=v,u=w,d=I)}let A=n[u][d],f=c.get(u),g=c.get(d),h=A/2+(f-g)/(2*(i-2)),y=A-h;h=Math.max(0,h),y=Math.max(0,y);let E={left:o[u],right:o[d],leftLength:h,rightLength:y};for(let x of a)if(x!==u&&x!==d){let S=(n[u][x]+n[d][x]-A)/2;n[u][x]=Math.max(0,S),n[x][u]=Math.max(0,S)}o[d]=void 0,o[u]=E,i--}let s=[];for(let a=0;a<o.length;a++)o[a]!==void 0&&s.push(a);if(s.length===2){let a=s[0],c=s[1],l=n[a][c];return{left:o[a],right:o[c],leftLength:l/2,rightLength:l/2}}return o[s[0]]}function OD(e,t){return t===void 0?e:`${e}:${t.toFixed(6)}`}function rj(e){let t=[],r=[e];for(;r.length>0;){let o=r.pop();t.push(o),o.left&&r.push(o.left),o.right&&r.push(o.right)}let n=new Map;for(let o=t.length-1;o>=0;o--){let i=t[o];if(i.name!==void 0&&!i.left&&!i.right)n.set(i,`'${i.name.replaceAll("'","''")}'`);else{let s=i.left?OD(n.get(i.left),i.leftLength):"",a=i.right?OD(n.get(i.right),i.rightLength):"";n.set(i,`(${s},${a})`)}}return n.get(e)}function UD(e){if(e.length<2)throw new Error("Need at least 2 sequences to build a tree");let t=e.map(o=>o[0]),r=ej(e),n=tj(r,t);return rj(n)+";"}var iA,XV,GD,HD=m(()=>{iA="ARNDCQEGHILKMFPSTWYVBZX*",XV=[[4,-1,-2,-2,0,-1,-1,0,-2,-1,-1,-1,-1,-2,-1,1,0,-3,-2,0,-2,-1,0,-4],[-1,5,0,-2,-3,1,0,-2,0,-3,-2,2,-1,-3,-2,-1,-1,-3,-2,-3,-1,0,-1,-4],[-2,0,6,1,-3,0,0,0,1,-3,-3,0,-2,-3,-2,1,0,-4,-2,-3,3,0,-1,-4],[-2,-2,1,6,-3,0,2,-1,-1,-3,-4,-1,-3,-3,-1,0,-1,-4,-3,-3,4,1,-1,-4],[0,-3,-3,-3,9,-3,-4,-3,-3,-1,-1,-3,-1,-2,-3,-1,-1,-2,-2,-1,-3,-3,-2,-4],[-1,1,0,0,-3,5,2,-2,0,-3,-2,1,0,-3,-1,0,-1,-2,-1,-2,0,3,-1,-4],[-1,0,0,2,-4,2,5,-2,0,-3,-3,1,-2,-3,-1,0,-1,-3,-2,-2,1,4,-1,-4],[0,-2,0,-1,-3,-2,-2,6,-2,-4,-4,-2,-3,-3,-2,0,-2,-2,-3,-3,-1,-2,-1,-4],[-2,0,1,-1,-3,0,0,-2,8,-3,-3,-1,-2,-1,-2,-1,-2,-2,2,-3,0,0,-1,-4],[-1,-3,-3,-3,-1,-3,-3,-4,-3,4,2,-3,1,0,-3,-2,-1,-3,-1,3,-3,-3,-1,-4],[-1,-2,-3,-4,-1,-2,-3,-4,-3,2,4,-2,2,0,-3,-2,-1,-2,-1,1,-4,-3,-1,-4],[-1,2,0,-1,-3,1,1,-2,-1,-3,-2,5,-1,-3,-1,0,-1,-3,-2,-2,0,1,-1,-4],[-1,-1,-2,-3,-1,0,-2,-3,-2,1,2,-1,5,0,-2,-1,-1,-1,-1,1,-3,-1,-1,-4],[-2,-3,-3,-3,-2,-3,-3,-3,-1,0,0,-3,0,6,-4,-2,-2,1,3,-1,-3,-3,-1,-4],[-1,-2,-2,-1,-3,-1,-1,-2,-2,-3,-3,-1,-2,-4,7,-1,-1,-4,-3,-2,-2,-1,-2,-4],[1,-1,1,0,-1,0,0,0,-1,-2,-2,0,-1,-2,-1,4,1,-3,-2,-2,0,0,0,-4],[0,-1,0,-1,-1,-1,-1,-2,-2,-1,-1,-1,-1,-2,-1,1,5,-2,-2,0,-1,-1,0,-4],[-3,-3,-4,-4,-2,-2,-3,-2,-2,-3,-2,-3,-1,1,-4,-3,-2,11,2,-3,-4,-3,-2,-4],[-2,-2,-2,-3,-2,-1,-2,-3,2,-1,-1,-2,-1,3,-3,-2,-2,2,7,-1,-3,-2,-1,-4],[0,-3,-3,-3,-1,-2,-2,-3,-3,3,1,-2,1,-1,-2,-2,0,-3,-1,4,-3,-2,-1,-4],[-2,-1,3,4,-3,0,1,-1,0,-3,-4,0,-3,-3,-2,0,-1,-4,-3,-3,4,1,-1,-4],[-1,0,0,1,-3,3,4,-2,0,-3,-3,1,-1,-3,-1,0,-1,-3,-2,-2,1,4,-1,-4],[0,-1,-1,-1,-2,-1,-1,-1,-1,-1,-1,-1,-1,-1,-2,0,0,-2,-1,-1,-1,-1,-1,-4],[-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,1]],GD=new Map;for(let e=0;e<iA.length;e++){let t=new Map;for(let r=0;r<iA.length;r++)t.set(iA[r],XV[e][r]);GD.set(iA[e],t)}});function wy(e){let t=[],r=0;for(;r<e.length&&(r=e.indexOf("{",r),r!==-1);){let n=1,o=r+1;for(r++;r<e.length&&n>0;)e[r]==="{"?n++:e[r]==="}"&&n--,r++;n===0&&t.push(e.slice(o,r-1).trim())}return t}function oj(e,t){let r=e.indexOf("{",t);if(r===-1)return;let n=1,o=r+1;for(;o<e.length&&n>0;)e[o]==="{"?n++:e[o]==="}"&&n--,o++;return n===0?e.slice(r+1,o-1).trim():void 0}function VD(e){let t=e.replace(/\s+/g," ").replace(/\s*{\s*/g,"{").replace(/\s*}\s*/g,"}").replace(/\s*,\s*/g,",").replace(/\s*::\s*=\s*/g,"::=").replace(/^.*?::=/,""),r=ij(t),{fdict:n,nodes:o}=r;if(n===void 0||o===void 0)throw new Error(`invalid BioTreeContainer ASN.1: missing '${n===void 0?"fdict":"nodes"}' section`);let i=Object.fromEntries(wy(n).flatMap(s=>{let a=sj(s);return a?[[a.id,nj[a.name]||a.name]]:[]}));return wy(o).flatMap(s=>{let a=aj(s);if(!a)return[];let{features:c=[],...l}=a;return[{...l,...Object.fromEntries(c.map(u=>[i[u.featureid],u.value]))}]})}function ij(e){let t={},r=e.trim();r.startsWith("{")&&r.endsWith("}")&&(r=r.slice(1,-1).trim());let n=0;for(;n<r.length;){for(;n<r.length&&/\s/.test(r[n]);)n++;if(n>=r.length)break;let o=n;for(;n<r.length&&/\w/.test(r[n]);)n++;if(n>=r.length||r[n]!==" "&&r[n]!=="{"){n=r.indexOf(",",n),n=n===-1?r.length:n+1;continue}let i=r.slice(o,n).trim();for(;n<r.length&&/\s/.test(r[n]);)n++;if(n>=r.length||r[n]!=="{"){n=r.indexOf(",",n),n=n===-1?r.length:n+1;continue}let s=1,a=n+1;for(n++;n<r.length&&s>0;)r[n]==="{"?s++:r[n]==="}"&&s--,n++;s===0&&(t[i]=r.slice(a,n-1).trim()),n=r.indexOf(",",n),n=n===-1?r.length:n+1}return t}function sj(e){let t=/id\s+(\d+)/.exec(e),r=/name\s+"((?:[^"\\]|\\.)*)"/s.exec(e);return!t||!r?null:{id:parseInt(t[1],10),name:r[1].replace(/\\"/g,'"').replace(/\\\\/g,"\\")}}function aj(e){let t=/id\s+(\d+)/.exec(e);if(!t)return null;let r=/parent\s+(\d+)/.exec(e),n=e.indexOf("features"),o=n!==-1?oj(e,n):void 0;return{id:parseInt(t[1],10),...r?{parent:parseInt(r[1],10)}:{},features:o?wy(o).flatMap(i=>{let s=cj(i);return s?[s]:[]}):[]}}function cj(e){let t=/featureid\s+(\d+)/.exec(e),r=/value\s+"((?:[^"\\]|\\.)*)"/s.exec(e);return!t||!r?null:{featureid:parseInt(t[1],10),value:r[1].replace(/\\"/g,'"').replace(/\\\\/g,"\\")}}var nj,jD=m(()=>{nj={$NODE_COLLAPSED:"collapsed",$NODE_COLOR:"color",$LABEL_BG_COLOR:"color","seq-id":"seqId","seq-title":"seqTitle","align-index":"alignIndex","accession-nbr":"accessionNbr","blast-name":"blastName","common-name":"commonName","leaf-count":"leafCount"}});function YD(e){let t=new Float64Array(Iy.length);return Array.from({length:e.numColumns},(r,n)=>{let o=e.total(n),i=0;if(o){t.fill(0);let s=0;if(e.forEachResidue(n,(a,c)=>{let l=WD[a];l>=0&&(t[l]+=c,s+=c)}),s>0){let a=0;for(let l of t)if(l>0){let u=l/s;a-=u*Math.log2(u)}let c=(o-s)/o;i=Math.max(0,1-a/lj)*(1-c)}}return i})}var $D,Iy,lj,WD,qD=m(()=>{gy();$D={A:"hydrophobic",V:"hydrophobic",L:"hydrophobic",I:"hydrophobic",M:"hydrophobic",C:"hydrophobic",F:"aromatic",W:"aromatic",Y:"aromatic",H:"aromatic",K:"positive",R:"positive",D:"negative",E:"negative",S:"polar",T:"polar",N:"polar",Q:"polar",G:"special",P:"special"},Iy=[...new Set(Object.values($D))],lj=Math.log2(Iy.length),WD=new Int8Array(yD).fill(-1);for(let[e,t]of Object.entries($D))WD[hD(e)]=Iy.indexOf(t)});function Sy(e,t){let r=0,n=0,o=0,i=e.length;for(;n<i&&e[n]===o;)n++,o++;for(;r<t;)for(r++,o++;n<i&&e[n]===o;)n++,o++;return o}function zD(e,t){let r=0,n=e.length-1;for(;r<=n;){let i=Math.floor((r+n)/2);if(e[i]===t)return;e[i]<t?r=i+1:n=i-1}return t-r}function uj({seq:e,blanks:t,visibleCol:r}){let n=Sy(t,r),o=e.length;if(n<o&&uf(e[n]))return;let i=0;for(let s=0;s<n&&s<o;s++)uf(e[s])||i++;return n<o?i:void 0}function JD({rowName:e,visibleCol:t,rowMap:r,blanks:n}){let o=r.get(e);return o!==void 0?uj({seq:o,visibleCol:t,blanks:n}):void 0}var KD=m(()=>{Co()});function XD(e){let t=new Int32Array(e.length),r=0;for(let n=0;n<e.length;n++)e.charCodeAt(n)-45>>>0<=1||(t[r++]=n);return t.subarray(0,r)}var ZD=m(()=>{Co()});function eN(e,t){let r=URL.createObjectURL(e),n=document.createElement("a");n.href=r,n.download=t,n.click(),setTimeout(()=>{URL.revokeObjectURL(r)},4e4)}var tN=m(()=>{});function xj(e){return e.startsWith("BioTreeContainer")?vD(VD(e)):Mi(e.startsWith("SEQ")?dd(e).tree:e)}function Cj(){return X.types.compose(kD(),PD(),ND(),X.types.model("MsaView",{id:Ui.ElementId,showDomains:he(X.types.boolean,!1),hideGaps:he(X.types.boolean,!0),allowedGappyness:he(X.types.number,100),subFeatureRows:he(X.types.boolean,!1),type:X.types.literal("MsaView"),drawMsaLetters:he(X.types.boolean,Ww),scrollZoom:he(X.types.boolean,Yw),height:he(X.types.number,550),rowHeight:he(X.types.number,16),scrollY:he(X.types.number,0),scrollX:he(X.types.number,0),colWidth:he(X.types.number,12),treeFilehandle:X.types.maybe(Ui.FileLocation),msaFilehandle:X.types.maybe(Ui.FileLocation),treeMetadataFilehandle:X.types.maybe(Ui.FileLocation),gffFilehandle:X.types.maybe(Ui.FileLocation),currentAlignment:he(X.types.number,0),collapsed:he(X.types.array(X.types.string),[]),showOnly:X.types.maybe(X.types.string),turnedOffTracks:he(X.types.map(X.types.boolean),{}),data:X.types.optional(RD(),{tree:"",msa:"",treeMetadata:""}),featureFilters:he(X.types.map(X.types.boolean),{}),relativeTo:X.types.maybe(X.types.string),highlightColumns:X.types.frozen()})).volatile(()=>({headerHeight:0,status:void 0,highResScaleFactor:typeof window>"u"?1:window.devicePixelRatio,loadingMSA:!1,loadingTree:!1,volatileWidth:void 0,resizeHandleWidth:5,blockSize:500,mouseRow:void 0,mouseCol:void 0,mouseClickRow:void 0,mouseClickCol:void 0,hoveredTreeNode:void 0,highlightedColumns:void 0,minimapHeight:56,conservationTrackHeight:40,marginLeft:20,error:void 0,interProAnnotations:void 0})).actions(e=>({drawRelativeTo(t){e.relativeTo=t},setHideGaps(t){e.hideGaps=t},setAllowedGappyness(t){e.allowedGappyness=t},setLoadingMSA(t){e.loadingMSA=t},setLoadingTree(t){e.loadingTree=t},setWidth(t){e.volatileWidth=t},setHighResScaleFactor(t){e.highResScaleFactor=t},setHeight(t){e.height=t},setError(t){e.error=t},setMousePos(t,r){e.mouseCol=t,e.mouseRow=r},setHighlightedColumns(t){e.highlightedColumns=t},setShowDomains(t){e.showDomains=t},setSubFeatureRows(t){e.subFeatureRows=t},setMouseClickPos(t,r){e.mouseClickCol=t,e.mouseClickRow=r},setRowHeight(t){e.rowHeight=t},setColWidth(t){e.colWidth=t},setScrollY(t){e.scrollY=t},setCurrentAlignment(t){e.currentAlignment=t},toggleCollapsed(t){e.collapsed.includes(t)?e.collapsed.remove(t):e.collapsed.push(t)},setShowOnly(t){e.showOnly=t},setData(t){e.data=(0,X.cast)(t)},setMSAFilehandle(t){e.msaFilehandle=t},setTreeFilehandle(t){e.treeFilehandle=t},setGFFFilehandle(t){e.gffFilehandle=t},setMSA(t){e.data.setMSA(t)},setTree(t){e.data.setTree(t)},setTreeMetadata(t){e.data.setTreeMetadata(t)}})).views(e=>({get hideGapsEffective(){return e.hideGaps&&(e.collapsed.length>0||e.allowedGappyness<100)},get realAllowedGappyness(){return this.hideGapsEffective?e.allowedGappyness:100},get actuallyShowDomains(){return e.showDomains&&!!e.interProAnnotations},get viewInitialized(){return e.volatileWidth!==void 0},get width(){if(e.volatileWidth===void 0)throw new Error("not initialized");return e.volatileWidth}})).views(e=>({extraViewMenuItems(){return[]},get colorScheme(){return rl[e.colorSchemeName]??rl[nf]},get header(){return this.MSA?.getHeader()??{}},get alignmentNames(){return this.MSA?.alignmentNames??[]},get noTree(){return!!this.tree.noTree},get noDomains(){return!e.interProAnnotations},menuItems(){return[]},get treeMetadata(){let t=e.data.treeMetadata;if(!t)return{};try{let r=JSON.parse(t);return typeof r=="object"&&r!==null?r:{}}catch(r){return console.error("failed to parse treeMetadata",r),{}}},get MSA(){let t=e.data.msa;return t?b0(t,e.currentAlignment,e.msaFormat):null},get numColumns(){return(this.MSA?.getWidth()??0)-this.blanks.length},get tree(){let t=e.data.tree;return t?ma(xj(t)):this.MSA?.getTree()??{noTree:!0,children:[],id:"empty",name:"empty"}},get rowNames(){return this.leaves.map(t=>t.data.name)},get rowNamesSet(){return new Map(this.leaves.map((t,r)=>[t.data.name,r]))},get mouseOverRowName(){let{mouseRow:t}=e;return t===void 0?void 0:this.leaves[t]?.data.name},get hoveredInsertion(){let{mouseCol:t,mouseRow:r}=e;if(t!==void 0&&r!==void 0){let n=this.leaves[r]?.data.name;if(n){let o=this.insertionPositions.get(n)?.find(i=>i.pos===t);if(o)return{rowName:n,col:t,letters:o.letters}}}},get root(){let t=CI(this.tree,r=>r.children);if(bI(t,r=>r.children.length>0?0:1),EI(t,(r,n)=>(r.data.length??1)-(n.data.length??1)),e.showOnly){let r=Af(t,n=>n.data.id===e.showOnly);r&&(t=r)}for(let r of e.collapsed){let n=Af(t,o=>o.data.id===r);n&&(n.children?SI(n):n.parent?.children&&(n.parent.children=n.parent.children.filter(o=>o.data.id!==r)))}return t},get msaAreaWidth(){return e.width-e.treeAreaWidth-e.resizeHandleWidth},get treeAreaWidthMinusMargin(){return e.treeAreaWidth-e.marginLeft},get blanks(){let{hideGapsEffective:t,realAllowedGappyness:r}=e;if(!t)return[];let n=this.leaves.map(l=>this.MSA?.getRow(l.data.name)).filter(nt.notEmpty);if(n.length===0)return[];let o=n.reduce((l,u)=>Math.max(l,u.length),0),i=n.length,s=Math.ceil(r/100*i),a=new Uint32Array(o);for(let l=0;l<i;l++){let u=n[l],d=u.length;for(let A=0;A<o;A++)(A>=d||u.charCodeAt(A)-45>>>0<=1)&&a[A]++}let c=[];for(let l=0;l<o;l++)a[l]>=s&&c.push(l);return c},get blanksSet(){return new Set(this.blanks)},get insertionPositions(){let{blanks:t,rows:r}=this;if(t.length===0||!e.hideGapsEffective)return new Map;let n=new Map;for(let[o,i]of r){let s=hI(t,i);s.length>0&&n.set(o,s)}return n},get rows(){let t=this.MSA;return this.leaves.map(r=>[r.data.name,t?.getRow(r.data.name)]).filter(r=>!!r[1])},get numRows(){return this.leaves.length},get seqPosGlobalColIndex(){return new Map(this.rows.map(([t,r])=>[t,XD(r)]))},get rowMap(){return new Map(this.rows)},get columns(){let t=this.columns2d;return new Map(this.rows.map((r,n)=>[r[0],t[n]]))},get columns2d(){let{hideGapsEffective:t}=e;return this.rows.map(([,r])=>(t?Jp(this.blanks,r):r).toUpperCase())},get fontSize(){return Math.min(Math.max(6,e.rowHeight-3),18)},get colStats(){return xD(this.columns2d)},get colStatsSums(){return this.colStats.totals},get sequenceType(){let t=this.colStats.lettersPresent,r=new Set(["A","C","G","T","N"]),n=new Set(["A","C","G","U","N"]),o=t.size>0&&[...t].every(s=>r.has(s)),i=t.size>0&&[...t].every(s=>n.has(s));return o?"dna":i?"rna":"amino"},get colConsensus(){let{colStats:t}=this;return Array.from({length:t.numColumns},(r,n)=>{let o=t.total(n),i=0,s="";t.forEachResidue(n,(c,l)=>{l>i&&(i=l,s=gD(c))});let a=o?i/o:0;return{letter:s,color:a>.4?`hsl(240, 30%, ${100*Math.max(1-a/3,.3)}%)`:void 0}})},get colClustalX(){let{colStats:t}=this;return Array.from({length:t.numColumns},(r,n)=>AD(t,n))},get conservation(){let{colStats:t,sequenceType:r}=this,o=Math.log2(r==="amino"?20:4);return Array.from({length:t.numColumns},(i,s)=>{let a=t.total(s),c=t.gapCount(s),l=a-c,u=0;if(l>0){let d=0;t.forEachResidue(s,(A,f)=>{let g=f/l;d-=g*Math.log2(g)}),u=Math.max(0,1-d/o)*(1-c/a)}return u})},get propertyConservation(){return this.sequenceType==="amino"?YD(this.colStats):[]},get hierarchy(){let t=this.root;II(t,this.totalHeight,e.treeWidth),t.data.length=0;let r=TI(t),n=r?e.treeWidth/r:0;return MI(t,0,n),Rc(t,o=>{if(o._children){let{min:i,max:s}=vI(o);o.collapsedTipXNear=(o.len??0)+i*n,o.collapsedTipXFar=(o.len??0)+s*n}}),t},get totalHeight(){return Mc(this.root).length*e.rowHeight},get leaves(){return Mc(this.hierarchy)},get maxBranchLength(){return BI(this.hierarchy)},get maxDepthToLeaf(){return Qc(this.hierarchy)},get allBranchesLength0(){return wI(this.hierarchy).every(t=>!t.source.data.length)},get showBranchLenEffective(){return this.allBranchesLength0?!1:e.showBranchLen}})).views(e=>({get totalWidth(){return e.numColumns*e.colWidth}})).views(e=>({get dataInitialized(){return(e.data.msa!==""||e.data.tree!=="")&&!e.error},get blocksX(){return my({viewportSize:e.msaAreaWidth,viewportPos:-e.scrollX,blockSize:e.blockSize,mapSize:e.totalWidth})},get blocksY(){return my({viewportSize:e.height,viewportPos:-e.scrollY,blockSize:e.blockSize,mapSize:e.totalHeight})}})).views(e=>({get blocks2d(){return e.blocksY.flatMap(t=>e.blocksX.map(r=>[r,t]))},get isLoading(){return e.loadingMSA||e.loadingTree},get maxScrollX(){return Math.min(-e.totalWidth+(e.msaAreaWidth-100),0)},get maxScrollY(){let t=e.height-e.headerHeight-(e.msaAreaWidth<e.totalWidth?e.minimapHeight:0);return Math.min(-e.totalHeight+t,0)},get showMsaLetters(){return e.drawMsaLetters&&e.rowHeight>=5&&e.colWidth>e.rowHeight/2},get showTreeText(){return e.drawLabels&&e.rowHeight>=5}})).actions(e=>({setDrawMsaLetters(t){e.drawMsaLetters=t},setScrollZoom(t){e.scrollZoom=t},setHoveredTreeNode(t){if(t){let r=Af(e.hierarchy,n=>n.data.id===t);e.hoveredTreeNode=r?{nodeId:t,descendantNames:Mc(r).map(n=>n.data.name)}:void 0}else e.hoveredTreeNode=void 0},calculateNeighborJoiningTreeFromMSA(){if(e.rows.length<2)throw new Error("Need at least 2 sequences to build a tree");let t=UD(e.rows);e.setTree(t)},resetZoom(){e.setColWidth(12),e.setRowHeight(16)},zoomOutHorizontal(){e.colWidth=Math.max(tf,Math.floor(e.colWidth*.75)),e.scrollX=(0,nt.clamp)(e.scrollX,e.maxScrollX,0)},zoomInHorizontal(){e.colWidth=Math.min(di,Math.ceil(e.colWidth*1.5)),e.scrollX=(0,nt.clamp)(e.scrollX,e.maxScrollX,0)},zoomInVertical(){e.rowHeight=Math.min(di,Math.ceil(e.rowHeight*1.5))},zoomOutVertical(){e.rowHeight=Math.max(rf,Math.floor(e.rowHeight*.75))},zoomIn(){(0,kt.transaction)(()=>{this.zoomInHorizontal(),this.zoomInVertical()})},zoomOut(){(0,kt.transaction)(()=>{this.zoomOutHorizontal(),this.zoomOutVertical()})},zoomToPos(t,r,n){(0,kt.transaction)(()=>{let o=(-e.scrollX+r)/e.colWidth,i=(-e.scrollY+n)/e.rowHeight;e.colWidth=(0,nt.clamp)(e.colWidth*t,tf,di),e.rowHeight=(0,nt.clamp)(e.rowHeight*t,rf,di),e.scrollX=(0,nt.clamp)(r-o*e.colWidth,e.maxScrollX,0);let s=n-i*e.rowHeight,a=Math.max(0,-e.maxScrollY),c=e.totalHeight-a,l=c>0?(0,nt.clamp)(1-a/c,0,1):1;e.scrollY=(0,nt.clamp)(s*(1-l),e.maxScrollY,0)})},doScrollY(t){e.scrollY=(0,nt.clamp)(e.scrollY+t,e.maxScrollY,0)},setDomains(t){e.interProAnnotations=t,e.setShowDomains(!!t)},applyGFFText(t){let r=Ad(t);this.setDomains(md(r))},doScrollX(t){this.setScrollX(e.scrollX+t)},setScrollX(t){e.scrollX=(0,nt.clamp)(t,e.maxScrollX,0)},toggleTrack(t){e.turnedOffTracks.has(t)?e.turnedOffTracks.delete(t):e.turnedOffTracks.set(t,!0)},setStatus(t){e.status=t}})).views(e=>({get labelWidthMap(){let{rowHeight:t,leaves:r,treeMetadata:n,fontSize:o}=e;return t<=5?new Map:new Map(r.map(i=>{let{name:s}=i.data,a=n[s]?.genome??s;return[s,TD(a,o)]}))},get labelsWidth(){let t=this.labelWidthMap;return t.size===0?0:Math.max(...t.values())},get secondaryStructureConsensus(){return e.MSA?.secondaryStructureConsensus},get seqConsensus(){return e.MSA?.seqConsensus},get adapterTrackModels(){let{rowHeight:t,MSA:r,hideGapsEffective:n,blanks:o}=e;return(r?.tracks??[]).filter(s=>!!s.data).map(s=>({model:{...s,data:n?Jp(o,s.data):s.data,height:t},ReactComponent:bD}))},get tracks(){let t={model:{id:"conservation",name:"Conservation",height:e.conservationTrackHeight,barColor:"gray"},ReactComponent:yy},r={model:{id:"property-conservation",name:"Property conservation",height:e.conservationTrackHeight,barColor:"#6a51a3"},ReactComponent:yy};return[...this.adapterTrackModels,t,...e.sequenceType==="amino"?[r]:[]]},get turnedOnTracks(){return this.tracks.filter(t=>!e.turnedOffTracks.has(t.model.id))},get showHorizontalScrollbar(){return e.msaAreaWidth<e.totalWidth},visibleColToRowLetter(t,r){let{rowMap:n,blanks:o}=e;return n.get(t)?.[Sy(o,r)]},visibleColToSeqPos(t,r){return JD({rowName:t,visibleCol:r,rowMap:e.rowMap,blanks:e.blanks})},visibleColToSeqPosOneBased(t,r){let n=this.visibleColToSeqPos(t,r);return n!==void 0?n+1:void 0},globalColToVisibleCol(t){let{blanks:r,hideGapsEffective:n}=e;return n?zD(r,t):t},seqPosToGlobalCol(t,r){let n=e.rowMap.get(t);return n===void 0?0:e.seqPosGlobalColIndex.get(t)?.[r]??(r===0?0:n.length)},seqPosToVisibleCol(t,r){let n=this.seqPosToGlobalCol(t,r);return this.globalColToVisibleCol(n)}})).views(e=>({get msaAreaHeight(){return e.height-(e.showHorizontalScrollbar?e.minimapHeight:0)-e.headerHeight},get totalTrackAreaHeight(){return(0,nt.sum)(e.turnedOnTracks.map(t=>t.model.height))},get tidyInterProAnnotationTypes(){return new Map(this.tidyInterProAnnotations.map(t=>[t.accession,t]))},get tidyInterProAnnotations(){return e.interProAnnotations?Object.entries(e.interProAnnotations).flatMap(([t,r])=>r.matches.flatMap(({signature:n,locations:o})=>{let{entry:i}=n;return i?o.map(({start:s,end:a,strand:c})=>({id:t,name:i.name,accession:i.accession,description:i.description,featureType:i.featureType,start:s,end:a,strand:c})):[]})).toSorted((t,r)=>Kp(r)-Kp(t)):[]},get tidyFilteredInterProAnnotations(){return this.tidyInterProAnnotations.filter(t=>e.featureFilters.get(t.accession))},get tidyFilteredGatheredInterProAnnotations(){return(0,nt.groupBy)(this.tidyFilteredInterProAnnotations,t=>t.id)}})).views(e=>({get showVerticalScrollbar(){return e.msaAreaHeight<e.totalHeight}})).views(e=>({get verticalScrollbarWidth(){return e.showVerticalScrollbar?20:0},get segmentDomainTypes(){return[...e.tidyInterProAnnotationTypes.values()].filter(t=>Op.has(t.featureType??"")).toSorted((t,r)=>t.start-r.start)},get categoricalDomainTypes(){return[...e.tidyInterProAnnotationTypes.values()].filter(t=>!Op.has(t.featureType??""))},get fillPalette(){let t=Object.fromEntries(this.segmentDomainTypes.map((n,o)=>[n.accession,Gp[o%Gp.length]])),r=ID(this.categoricalDomainTypes.map(n=>n.accession));return{...t,...r}},get strokePalette(){return Us(this.fillPalette,([t,r])=>[t,st(r).darken(.1).toHex()])},get segmentLabels(){return new Map(this.segmentDomainTypes.map((t,r)=>{let n=/(\d+)\s*$/.exec(t.name);return[t.accession,n?n[1]:`${r+1}`]}))},get visibleDomainTypes(){return this.categoricalDomainTypes.filter(t=>e.featureFilters.get(t.accession)).toSorted((t,r)=>t.start-r.start)},get domainBands(){let t=new Map;for(let[r,n]of Object.entries(e.tidyFilteredGatheredInterProAnnotations)){let o=n.map((i,s)=>{let a=e.seqPosToVisibleCol(r,i.start-1),c=e.seqPosToVisibleCol(r,i.end-1);return a!==void 0&&c!==void 0?{annotation:i,startCol:a,endCol:c+1,stackIndex:s}:void 0}).filter(nt.notEmpty);o.length>0&&t.set(r,o)}return t},get domainBandsByStart(){return new Map([...this.domainBands].map(([t,r])=>[t,r.toSorted((n,o)=>n.startCol-o.startCol)]))},get mouseOverDomains(){let{mouseCol:t}=e,r=e.mouseOverRowName;return r!==void 0&&t!==void 0?(this.domainBands.get(r)??[]).filter(n=>t>=n.startCol&&t<n.endCol).map(n=>n.annotation):[]},get referenceRowIndex(){let{relativeTo:t}=e;return t===void 0?void 0:e.rowNamesSet.get(t)},get hoveredRowIndices(){let{hoveredTreeNode:t,rowNamesSet:r}=e;return t?t.descendantNames.map(n=>r.get(n)).filter(nt.notEmpty):[]},get highlightedColumnRuns(){let{highlightedColumns:t}=e,r=[];for(let n of[...t??[]].sort((o,i)=>o-i)){let o=r.at(-1);o&&n===o.end+1?o.end=n:r.push({start:n,end:n})}return r},get mouseOverColumnStats(){let{mouseCol:t}=e;if(t===void 0)return;let{colStats:r}=e,n=r.total(t);if(t>=r.numColumns||!n)return;let o=r.gapCount(t),i=r.residueEntries(t).sort((a,c)=>c[1]-a[1]),s=i[0];return{col:t,total:n,gaps:o,gapFraction:o/n,conservation:e.conservation[t]??0,propertyConservation:e.propertyConservation[t],consensusLetter:s?.[0]??"",consensusCount:s?.[1]??0,consensusFraction:s?s[1]/n:0,distribution:i}},getRowData(t){return{data:e.MSA?.getRowData(t),treeMetadata:e.treeMetadata[t]}}})).actions(e=>({setHeaderHeight(t){e.headerHeight=t},setConservationTrackHeight(t){e.conservationTrackHeight=t},reset(){e.setData({tree:"",msa:""}),e.resetZoom(),e.setError(void 0),e.setScrollY(0),e.setScrollX(0),e.setCurrentAlignment(0),e.setTreeFilehandle(void 0),e.setMSAFilehandle(void 0),e.setGFFFilehandle(void 0),e.setDomains(void 0)},async exportSVG(t){let{renderToSvg:r}=await Promise.resolve().then(()=>(fg(),OI)),n=await r(e,t),o=new Blob([n],{type:"image/svg+xml"});eN(o,"image.svg")},initFilter(t){e.featureFilters.has(t)||e.featureFilters.set(t,!0)},setFilter(t,r){e.featureFilters.set(t,r)},fit(){this.fitVertically(),this.fitHorizontally()},fitVertically(){e.numRows>0&&(e.rowHeight=(0,nt.clamp)(e.msaAreaHeight/e.numRows,rf,di)),e.scrollY=0},fitHorizontally(){e.numColumns>0&&(e.colWidth=(0,nt.clamp)(e.msaAreaWidth/e.numColumns,tf,di)),e.scrollX=0},afterCreate(){if(e.highlightColumns?.length&&e.setHighlightedColumns(e.highlightColumns),(0,X.addDisposer)(e,(0,kt.autorun)(()=>{for(let n of e.tidyInterProAnnotationTypes.keys())this.initFilter(n)})),typeof window<"u"&&typeof window.matchMedia=="function"){let n=()=>window.matchMedia(`(resolution: ${window.devicePixelRatio}dppx)`),o=n(),i=()=>{e.setHighResScaleFactor(window.devicePixelRatio),o.removeEventListener("change",i),o=n(),o.addEventListener("change",i)};o.addEventListener("change",i),(0,X.addDisposer)(e,()=>{o.removeEventListener("change",i)})}let t=0;(0,X.addDisposer)(e,(0,kt.autorun)(async()=>{let{treeFilehandle:n}=e;if(n){let o=++t;try{e.setLoadingTree(!0);let i=await nl((0,Tl.openLocation)(n),s=>{o===t&&e.setStatus(s)});o===t&&(0,kt.transaction)(()=>{e.setTree(i),n.locationType==="BlobLocation"&&e.setTreeFilehandle(void 0)})}catch(i){o===t&&(Qo(i)?e.setTreeFilehandle(void 0):(console.error(i),e.setError(i)))}finally{o===t&&e.setLoadingTree(!1)}}})),(0,X.addDisposer)(e,(0,kt.autorun)(async()=>{let{treeMetadataFilehandle:n}=e;if(n)try{e.setTreeMetadata(await nl((0,Tl.openLocation)(n),o=>{e.setStatus(o)}))}catch(o){Qo(o)||(console.error(o),e.setError(o))}})),(0,X.addDisposer)(e,(0,kt.autorun)(()=>{let n=e.data.gff;if(n)try{e.applyGFFText(n)}catch(o){console.error(o),e.setError(o)}})),(0,X.addDisposer)(e,(0,kt.autorun)(async()=>{let{gffFilehandle:n}=e;if(n)try{let o=await nl((0,Tl.openLocation)(n),i=>{e.setStatus(i)});e.applyGFFText(o),n.locationType==="BlobLocation"&&e.setGFFFilehandle(void 0)}catch(o){Qo(o)?e.setGFFFilehandle(void 0):(console.error(o),e.setError(o))}}));let r=0;(0,X.addDisposer)(e,(0,kt.autorun)(async()=>{let{msaFilehandle:n}=e;if(n){let o=++r;try{e.setLoadingMSA(!0),e.setError(void 0);let i=await nl((0,Tl.openLocation)(n),s=>{o===r&&e.setStatus(s)});o===r&&(0,kt.transaction)(()=>{e.setMSA(i),n.locationType==="BlobLocation"&&e.setMSAFilehandle(void 0)})}catch(i){o===r&&(Qo(i)?e.setMSAFilehandle(void 0):(console.error(i),e.setError(i)))}finally{o===r&&e.setLoadingMSA(!1)}}})),(0,X.addDisposer)(e,(0,kt.autorun)(()=>{e.colorSchemeName.includes("dynamic")&&e.colStats,e.showColumnStats&&(e.colStats,e.conservation,e.propertyConservation),e.columns})),(0,X.addDisposer)(e,(0,kt.autorun)(()=>{e.autoTreeAreaWidth&&(e.noTree||!e.drawTree)&&e.labelsWidth&&e.setTreeAreaWidth(e.labelsWidth+e.marginLeft+12)})),(0,X.addDisposer)(e,(0,kt.autorun)(()=>{e.setTreeWidth(Math.max(50,e.treeAreaWidth-e.labelsWidth-10-e.marginLeft))}))}})).postProcessSnapshot(({data:e,...t})=>({...t,data:{...t.treeFilehandle?{}:{tree:e.tree},...t.msaFilehandle?{}:{msa:e.msa},...t.treeMetadataFilehandle?{}:{treeMetadata:e.treeMetadata}}}))}var nt,Tl,Ui,X,kt,sA,vy=m(()=>{nt=p(we(),1),Tl=p(Ay(),1),Ui=p(aD(),1),X=p(Kt(),1);vc();kt=p(Ps(),1);w0();cD();mD();i0();gy();CD();ED();Ic();SD();fd();BD();og();MD();QD();DD();LD();FD();HD();jD();qD();KD();ZD();oA();Co();tN();sA=Cj});var By,oN,bj,Xme,iN=m(()=>{By=p(Q(),1),oN=p(oD(),1),bj=p(gg(),1);vy();dy();Xme=(0,oN.createJBrowseTheme)()});var Ty=m(()=>{fg();dy();iN();vy()});var fL=K((Qge,uL)=>{uL.exports=JBrowseExports["@jbrowse/core/data_adapters/BaseAdapter"]});var mL={};Bt(mL,{default:()=>xA});var dL,AL,xA,pL=m(()=>{"use strict";dL=p(as()),AL=p(fL());iT();xA=class extends AL.BaseAdapter{async configurePre(){let t=this.getSubAdapter;if(t)return(await t({...(0,dL.readConfObject)(this.config),type:"BgzipFastaAdapter"})).dataAdapter;throw new Error("no get subadapter")}configure(){return this.configureP??=this.configurePre().catch(t=>{throw this.configureP=void 0,t}),this.configureP}async getMSARefs(){return this.refNamesP??=this.configure().then(t=>t.getRefNames()).catch(t=>{throw this.refNamesP=void 0,t}),this.refNamesP}getMsaRegex(){return new RegExp(this.getConf("msaRegex"))}refNameToMsaId(t){return t.split(this.getMsaRegex())[0]}async getMSAList(){let t=await this.getMSARefs();return[...new Set(t.map(n=>this.refNameToMsaId(n)))]}async getMSA(t){let r=await this.configure(),o=(await this.getMSARefs()).filter(i=>this.refNameToMsaId(i)===t);return Qh(r.getFeaturesInMultipleRegions(o.map(i=>({refName:i,start:0,end:1e9,assemblyName:""}))).pipe(_h()))}}});var DL=K(kL=>{"use strict";var Na=Q();function y7(e,t){return e===t&&(e!==0||1/e===1/t)||e!==e&&t!==t}var x7=typeof Object.is=="function"?Object.is:y7,C7=Na.useState,b7=Na.useEffect,E7=Na.useLayoutEffect,w7=Na.useDebugValue;function I7(e,t){var r=t(),n=C7({inst:{value:r,getSnapshot:t}}),o=n[0].inst,i=n[1];return E7(function(){o.value=r,o.getSnapshot=t,Yy(o)&&i({inst:o})},[e,r,t]),b7(function(){return Yy(o)&&i({inst:o}),e(function(){Yy(o)&&i({inst:o})})},[e]),w7(r),r}function Yy(e){var t=e.getSnapshot;e=e.value;try{var r=t();return!x7(e,r)}catch{return!0}}function S7(e,t){return t()}var v7=typeof window>"u"||typeof window.document>"u"||typeof window.document.createElement>"u"?S7:I7;kL.useSyncExternalStore=Na.useSyncExternalStore!==void 0?Na.useSyncExternalStore:v7});var LL=K((Zge,NL)=>{"use strict";NL.exports=DL()});var wP,IP,SP=m(()=>{"use client";Ie();wP=p(O(),1),IP=Y((0,wP.jsx)("path",{d:"M19 19H5V5h7V3H5c-1.11 0-2 .9-2 2v14c0 1.1.89 2 2 2h14c1.1 0 2-.9 2-2v-7h-2zM14 3v2h3.59l-9.83 9.83 1.41 1.41L19 6.41V10h2V3z"}),"OpenInNew")});function qi(e){let{children:t,...r}=e;return dx.default.createElement(vP.Link,{...r,target:"_blank",rel:"noreferrer"},t," ",dx.default.createElement(IP,{fontSize:"small"}))}var dx,vP,OA=m(()=>{"use strict";dx=p(Q());SP();vP=p(U())});var sF=K((Nye,iF)=>{iF.exports=JBrowseExports["@jbrowse/core/pluggableElementTypes/ViewType"]});var Fl,aF,jA,cF=m(()=>{"use strict";Fl=p(Q()),aF=p(Ze()),jA=class extends Fl.Component{constructor(t){super(t),this.state={hasError:!1,error:null}}static getDerivedStateFromError(t){return{hasError:!0,error:t}}componentDidCatch(t,r){console.error("MsaViewPanel error:",t,r.componentStack)}render(){return this.state.hasError?Fl.default.createElement("div",{style:{padding:20}},Fl.default.createElement(aF.ErrorMessage,{error:this.state.error})):this.props.children}}});function p$({baseUrl:e,rid:t}){return bx.default.createElement(lF.Typography,null,"RID ",t," (",bx.default.createElement(qi,{href:`${e}?CMD=Get&RID=${t}`},"see status"),")")}var bx,lF,Ex,uF=m(()=>{"use strict";bx=p(Q()),lF=p(U());OA();Ex=p$});function g$({baseUrl:e,rid:t,error:r}){return Or.default.createElement("div",null,t?Or.default.createElement(Ex,{rid:t,baseUrl:e}):null,Or.default.createElement($A.ErrorMessage,{error:r}))}function h$({baseUrl:e,rid:t,progress:r}){let{classes:n}=AF();return Or.default.createElement("div",{className:n.loading},t?Or.default.createElement(Ex,{baseUrl:e,rid:t}):null,Or.default.createElement(wx.Typography,null,r))}var Or,$A,wx,fF,dF,AF,y$,mF,pF=m(()=>{"use strict";Or=p(Q()),$A=p(Ze()),wx=p(U()),fF=p(W()),dF=p(Tt());uF();AF=(0,dF.makeStyles)()(e=>({margin:{padding:20},loading:{background:e.palette.background.paper}}));y$=(0,fF.observer)(function({model:t,baseUrl:r}){let{progress:n,rid:o,error:i}=t,{classes:s}=AF();return Or.default.createElement("div",{className:s.margin},Or.default.createElement($A.LoadingEllipses,{message:"Running NCBI BLAST",variant:"h5"}),i?Or.default.createElement(g$,{baseUrl:r,rid:o,error:i}):o?Or.default.createElement(h$,{baseUrl:r,rid:o,progress:n}):Or.default.createElement(wx.Typography,null,n||"Initializing BLAST query"))}),mF=y$});var xF={};Bt(xF,{default:()=>b$});var Ji,gF,hF,yF,x$,C$,b$,CF=m(()=>{"use strict";Ji=p(Q()),gF=p(Ze()),hF=p(W());Ty();yF=p(Tt());cF();pF();x$=(0,yF.makeStyles)()({loadingContainer:{padding:20}}),C$=(0,hF.observer)(function({model:t}){let{classes:r}=x$(),{blastParams:n,loadingStoredData:o}=t;return Ji.default.createElement(jA,null,Ji.default.createElement("div",null,n?Ji.default.createElement(mF,{model:t,baseUrl:n.baseUrl}):o?Ji.default.createElement("div",{className:r.loadingContainer},Ji.default.createElement(gF.LoadingEllipses,{message:"Loading MSA data",variant:"h6"})):Ji.default.createElement(eA,{model:t})))}),b$=C$});var w$={};Bt(w$,{default:()=>WA});var IF=p($x()),Sx=p(as()),SF=p(we()),vx=p(Kt());Ie();var kw=p(O(),1),Dw=Y((0,kw.jsx)("path",{d:"M20 2H4c-1.1 0-2 .9-2 2v16c0 1.1.9 2 2 2h16c1.1 0 2-.9 2-2V4c0-1.1-.9-2-2-2M8 20H4v-4h4zm0-6H4v-4h4zm0-6H4V4h4zm6 12h-4v-4h4zm0-6h-4v-4h4zm0-6h-4V4h4zm6 12h-4v-4h4zm0-6h-4v-4h4zm0-6h-4V4h4z"}),"GridOn");var aL=p(Q()),cL=p(we());var kl=p(Q()),iL=p(W());var Py=p(Q()),tL=p(we()),Fy=p(W());var Fw=p(Tt());function ui(e){return!!e&&typeof e=="object"&&"hoverPosition"in e&&!!e.hoverPosition}function Pw(e){return/AF-([A-Z0-9]+)-F\d+/.exec(e)?.[1]}var Zu=(0,Fw.makeStyles)()({highlight:{height:"100%",background:"rgba(255,255,0,0.2)",border:"1px solid rgba(50,50,0,0.2)",position:"absolute",zIndex:99,textAlign:"center",pointerEvents:"none",overflow:"hidden"}});var ZN=p(Pp()),eL=p(we()),gt=p(Kt());function Gw(e){let t=e.strand,r=e.refName;if(t!==-1&&t!==1)throw new Error(`Invalid strand value: ${t}. Expected 1 or -1.`);if(!r)throw new Error("refName is required");let n=new Map;for(let c of e.subfeatures??[])if(c.type==="CDS"&&c.start<c.end){let l=`${c.start}-${c.end}`;n.has(l)||n.set(l,c)}let o=[...n.values()].sort((c,l)=>t*(c.start-l.start)),i={},s={},a={};if(o.length!==0){let l=(3-(o[0]?.phase??0))%3,u=-1;for(let d of o){let A=d.end-d.start;for(let f=0;f<A;f++){let g=t===1?d.start+f:d.end-1-f,h=Math.floor(l++/3);i[g]=h,h!==u?(s[h]=g,a[h]=[g],u=h):a[h].push(g)}}}return{g2p:i,p2g:s,p2gCodon:a,refName:r,strand:t}}function Uw(e,t){let r=e[t];if(r===void 0)return;let n=[...r].sort((i,s)=>i-s),o=[];for(let i of n){let s=o.at(-1);s?.[1]===i?s[1]=i+1:o.push([i,i+1])}return o}var yA=p(Ps());Ty();var HN=p(we());function sN(e,t){let r=e.sciname.replaceAll(" ","_");if(e.taxid&&t?.has(e.taxid)){let n=t.get(e.taxid);n.commonName&&(r=n.commonName.split(" ").map(o=>o.charAt(0).toUpperCase()+o.slice(1).toLowerCase()).join("_"))}return`${e.accession}-${r}`}function aN(e){return e.replaceAll("-","")}var cA=p(we());function tr(e){return(0,cA.getContainingView)(e)}function cN(e){return[...new Set(e.filter(t=>!!t))]}function lN(e,t){return t.filter(r=>!!r).join(e)}function Ej(e){let r=(e.get("subfeatures")??[]).filter(n=>(n.get("type")==="mRNA"||n.get("type")==="transcript")&&n.get("subfeatures")?.some(o=>o.get("type")==="CDS"));return r.length>0?r:[e]}function aA(e){let t=(0,cA.sum)(e.get("subfeatures")?.filter(r=>r.get("type")==="CDS").map(r=>r.get("end")-r.get("start"))??[]);return{len:Math.floor(t/3),mod:t%3}}function Hi(e){return e?.id()??""}function wj(e){return e?cN([e.id(),e.get("name"),e.get("id"),e.get("transcript_id")]):[]}function Ta(e,t){return wj(e).includes(t)}function Ma(e){return e?lN(" ",[e.get("name"),e.get("id")]):""}function io(e){return e?lN(" ",[e.get("gene_name")??e.get("name"),e.get("id")?`(${e.get("id")})`:void 0]):""}function lA(e,t){return`BLAST - ${io(e)} - ${Ma(t)}`}function uA(e){return Ej(e).toSorted((r,n)=>aA(n).len-aA(r).len)}function Ra(e){return e.replaceAll("*","").replaceAll("&","")}function Qa(e){return cN([e.id(),e.get("id"),e.get("name"),e.get("gene_id"),e.get("gene_name")])}Uh();function $o(e,t,r){let n;return()=>(n??=Gh(e,t,{upgrade:r}).catch(o=>{throw n=void 0,o}),n)}var Ij="jbrowse-msaview-blast-cache",Vi="blast-results",Sj=2,My=$o(Ij,Sj,(e,t)=>{t<2&&e.objectStoreNames.contains(Vi)&&e.deleteObjectStore(Vi),e.objectStoreNames.contains(Vi)||e.createObjectStore(Vi,{keyPath:"id"})});function vj(e,t,r,n,o){let i=o?`:${o}`:"";return`${t}:${r}:${n}${i}:${e}`}async function uN({proteinSequence:e,blastDatabase:t,blastProgram:r,msaAlgorithm:n,msa:o,tree:i,treeMetadata:s,rid:a,geneId:c,transcriptId:l,transcriptName:u,geneName:d}){let A=await My(),g={id:vj(e,t,r,n,l),proteinSequence:e,blastDatabase:t,blastProgram:r,msaAlgorithm:n,msa:o,tree:i,treeMetadata:s,rid:a,timestamp:Date.now(),geneId:c,transcriptId:l,transcriptName:u,geneName:d};return await A.put(Vi,g),g}async function fN(){return(await(await My()).getAll(Vi)).toSorted((r,n)=>n.timestamp-r.timestamp)}async function Ry(e){await(await My()).delete(Vi,e)}async function dN(e,t){let r=await fetch(e,t);if(!r.ok)throw new Error(`HTTP ${r.status} fetching ${e} ${await r.text()}`);return r}async function zt(e,t){return(await dN(e,t)).text()}async function _a(e,t){return(await dN(e,t)).json()}function AN(e){return new Promise(t=>setTimeout(t,e))}async function fA({check:e,intervalSeconds:t,onCountdown:r}){for(;;){if(await e())return;for(let n=t;n>0;n--)r(n),await AN(1e3)}}var AA="https://www.ebi.ac.uk/Tools/services/rest",dA="colin.diesh@gmail.com",Bj={clustalo:{params:{email:dA},msaResult:"aln-clustal_num",treeResult:"phylotree"},muscle:{params:{email:dA,format:"clw",tree:"tree1"},msaResult:"fa",treeResult:"phylotree"},kalign:{params:{email:dA,stype:"protein"},msaResult:"fa",treeResult:"phylotree"},mafft:{params:{email:dA,stype:"protein"},msaResult:"fa",treeResult:"phylotree"}};async function Tj({onProgress:e,jobId:t,algorithm:r}){await fA({intervalSeconds:10,onCountdown:n=>{e(`Re-checking MSA status in... ${n}`)},check:async()=>{let n=await zt(`${AA}/${r}/status/${t}`);if(n.includes("FINISHED"))return!0;if(n.includes("FAILURE"))throw new Error(`Failed to run: jobId ${t}`);return!1}})}async function mA({algorithm:e,sequence:t,onProgress:r}){let n=Bj[e];r(`Launching ${e} MSA...`);let o=await zt(`${AA}/${e}/run`,{method:"POST",body:new URLSearchParams({...n.params,sequence:t})});return await Tj({jobId:o,algorithm:e,onProgress:r}),{msa:await zt(`${AA}/${e}/result/${o}/${n.msaResult}`),tree:await zt(`${AA}/${e}/result/${o}/${n.treeResult}`)}}async function Qy({rid:e,baseUrl:t,onProgress:r}){r(`Checking BLAST status for RID: ${e}...`),await Rj({rid:e,onProgress:r,baseUrl:t});let n=await _a(`${t}?CMD=Get&RID=${e}&FORMAT_TYPE=JSON2_S&FORMAT_OBJECT=Alignment`);return{rid:e,hits:n.BlastOutput2[0]?.report.results.search.hits??[]}}async function mN({query:e,blastDatabase:t,blastProgram:r,baseUrl:n,onProgress:o,onRid:i}){o("Submitting to NCBI BLAST...");let{rid:s}=await Mj({query:e,blastDatabase:t,blastProgram:r,baseUrl:n});return i(s),Qy({rid:s,baseUrl:n,onProgress:o})}async function Mj({query:e,blastProgram:t,blastDatabase:r,baseUrl:n}){let o=await zt(n,{method:"POST",body:new URLSearchParams({CMD:"Put",PROGRAM:t==="quick-blastp"?"blastp":t,DATABASE:r,QUERY:e,...r==="nr_cluster_seq"?{CLUSTERED_DB:"on",DB_TYPE:"Experimental Databases"}:{},...t==="quick-blastp"?{BLAST_PROGRAMS:"kmerBlastp"}:{}})}),i=/^ {4}RID = (.*$)/m.exec(o)?.[1],s=/^ {4}RTOE = (.*$)/m.exec(o)?.[1];if(!i)throw new Error("Failed to get RID from BLAST request");return{rid:i,rtoe:s}}async function Rj({rid:e,onProgress:t,baseUrl:r}){await fA({intervalSeconds:20,onCountdown:n=>{t(`Re-checking BLAST status in... ${n}`)},check:async()=>{let n=await zt(`${r}?CMD=Get&FORMAT_OBJECT=SearchInfo&RID=${e}`),o=/\s+Status=(\S+)/m.exec(n)?.[1],i=/\s+ThereAreHits=yes/m.test(n);if(o==="WAITING")return!1;if(o==="FAILED")throw new Error(`BLAST ${e} failed`);if(o==="READY"){if(i)return!0;throw new Error("No hits found")}throw new Error(`BLAST ${e} returned unexpected status: ${o??"unknown"}`)}})}var _y="jbrowse-plugin-msaview",ky="colin.diesh@gmail.com",Qj="https://eutils.ncbi.nlm.nih.gov/entrez/eutils";function pA(e){let t=new URLSearchParams({...e,tool:_y,email:ky});return`${Qj}/efetch.fcgi?${t.toString()}`}var _j="jbrowse-msaview-taxonomy-cache",Ml="common-names",kj=2,pN=$o(_j,kj,e=>{e.objectStoreNames.contains(Ml)&&e.deleteObjectStore(Ml),e.createObjectStore(Ml,{keyPath:"taxid"})});async function Dj(e){let r=(await pN()).transaction(Ml,"readonly"),n=await Promise.all(e.map(o=>r.store.get(o)));return await r.done,n}async function Nj(e){let r=(await pN()).transaction(Ml,"readwrite");for(let n of e)await r.store.put(n);await r.done}async function gN(e){let t=new Map,r=[],n=await Dj(e);for(let s=0;s<e.length;s++){let a=e[s],c=n[s];c?t.set(a,{sciname:c.sciname,commonName:c.commonName}):r.push(a)}if(r.length===0)return t;let o=100,i=[];for(let s=0;s<r.length;s+=o){let a=r.slice(s,s+o),c=a.join(",");try{let l=await zt(pA({db:"taxonomy",id:c,retmode:"xml"})),u=new Map,d=/<Taxon>\s*<TaxId>(\d+)<\/TaxId>/g,A;for(;(A=d.exec(l))!==null;){let f=Number(A[1]),g=A.index,h=1,y=g+A[0].length;for(;h>0&&y<l.length;){let I=l.indexOf("<Taxon>",y),v=l.indexOf("</Taxon>",y);if(v===-1)break;I!==-1&&I<v?(h++,y=I+7):(h--,y=v+8)}let E=l.slice(g,y),x=u.get(f),S=E.includes("<LineageEx>"),w=x?.includes("<LineageEx>");(!x||S&&!w)&&u.set(f,E)}for(let f of a){let g=u.get(f);if(g){let h=/<GenbankCommonName>(.*?)<\/GenbankCommonName>/.exec(g),y=/<CommonName>(.*?)<\/CommonName>/.exec(g),E=/<ScientificName>(.*?)<\/ScientificName>/.exec(g),x=h?.[1]??y?.[1],S=E?.[1]??"";t.set(f,{sciname:S,commonName:x}),i.push({taxid:f,sciname:S,commonName:x})}}}catch(l){console.error("Failed to fetch taxonomy data:",l)}}return i.length>0&&await Nj(i),t}async function hN({self:e}){let{baseUrl:t,blastDatabase:r,blastProgram:n,msaAlgorithm:o,proteinSequence:i,selectedTranscript:s,rid:a}=e.blastParams,c=Ra(i),l=x=>{e.setProgress(x)};a&&e.setRid(a);let{hits:u,rid:d}=a?await Qy({rid:a,baseUrl:t,onProgress:l}):await mN({query:c,blastDatabase:r,blastProgram:n,baseUrl:t,onProgress:l,onRid:x=>{e.setRid(x)}});e.setProgress("Fetching species taxonomy info...");let A=u.map(x=>x.description[0]?.taxid).filter(x=>x!==void 0),f=await gN(A),g={},h=u.map(x=>{let S=x.description[0]??{accession:"unknown",id:"unknown",sciname:"unknown"},w=sN(S,f),I=aN(x.hsps[0]?.hseq??"");return g[w]=Lj(S,f),`>${w}
-${I}`}),y=await mA({algorithm:o,sequence:[`>QUERY
-${c}`,...h].join(`
-`),onProgress:l}),E=JSON.stringify(g);return await uN({proteinSequence:c,blastDatabase:r,blastProgram:n,msaAlgorithm:o,msa:y.msa,tree:y.tree,treeMetadata:E,rid:d,geneId:s?.get("parentId"),transcriptId:s?.id(),transcriptName:s?.get("name")??s?.get("id"),geneName:s?.get("gene_name")??s?.get("parentId")}),{...y,treeMetadata:E}}function Lj(e,t){let r={},n=e.taxid?t.get(e.taxid):void 0;return n?.sciname&&(r["Scientific name"]=n.sciname),n?.commonName&&(r["Common name"]=n.commonName),e.accession&&(r.Accession=e.accession),e.id&&(r.ID=e.id),e.title&&(r.Description=e.title),r}var xN="https://api.ncbi.nlm.nih.gov/datasets/v2",Dy="https://eutils.ncbi.nlm.nih.gov/entrez/eutils",ji=[{label:"Human",taxId:9606},{label:"Chimpanzee",taxId:9598},{label:"Gorilla",taxId:9595},{label:"Rhesus macaque",taxId:9544},{label:"Marmoset",taxId:9483},{label:"Mouse",taxId:10090},{label:"Rat",taxId:10116},{label:"Guinea pig",taxId:10141},{label:"Rabbit",taxId:9986},{label:"Cat",taxId:9685},{label:"Dog",taxId:9615},{label:"Horse",taxId:9796},{label:"Pig",taxId:9823},{label:"Cow",taxId:9913},{label:"Sheep",taxId:9940},{label:"Opossum",taxId:13616},{label:"Chicken",taxId:9031},{label:"Frog",taxId:8364},{label:"Zebrafish",taxId:7955},{label:"Fruitfly",taxId:7227},{label:"C. elegans",taxId:6239},{label:"Yeast",taxId:4932},{label:"Arabidopsis",taxId:3702}],yN=new Map(ji.map((e,t)=>[e.taxId,t]));function Rl(e){let t=e.includes("?")?"&":"?";return`${e}${t}tool=${_y}&email=${encodeURIComponent(ky)}`}async function CN(e,t){for(let r of e){let n=r.trim();if(!n)continue;if(/^\d+$/.test(n))return{geneId:n,matched:n};let o=n.replace(/^\w+:/,"").replace(/\.\d+$/,""),i=`${o}[Gene Name] AND ${t}[taxid]`,a=(await _a(Rl(`${Dy}/esearch.fcgi?db=gene&term=${encodeURIComponent(i)}&retmode=json&retmax=1`))).esearchresult?.idlist?.[0];if(a)return{geneId:a,matched:o}}}async function Pj(e,t){let r=await _a(Rl(`${xN}/gene/id/${e}/orthologs?returned_content=COMPLETE`)),n=new Map;for(let{gene:o}of r.reports??[]){let i=Number(o?.tax_id);o?.gene_id&&t.has(i)&&!n.has(i)&&n.set(i,{taxId:i,geneId:o.gene_id,scientificName:o.taxname??String(i),commonName:o.common_name})}return[...n.values()].sort((o,i)=>(yN.get(o.taxId)??1/0)-(yN.get(i.taxId)??1/0))}async function bN(e){let t=new Map;if(e.length>0){let r=await _a(Rl(`${xN}/gene/id/${e.join(",")}/product_report`));for(let{product:n}of r.reports??[]){let o=(n?.transcripts??[]).map(s=>({acc:s.protein?.accession_version,len:s.protein?.length??0,mane:/select/i.test(s.select_category??"")})).filter(s=>!!s.acc),i=o.find(s=>s.mane)??[...o].sort((s,a)=>a.len-s.len).at(0);n?.gene_id&&i&&t.set(n.gene_id,i.acc)}}return t}function EN(e){let t=new Map,r,n=[];for(let o of e.split(`
-`))o.startsWith(">")?(r&&t.set(r,n.join("")),r=o.slice(1).split(/\s+/)[0],n=[]):n.push(o.trim());return r&&t.set(r,n.join("")),t}function Fj(e){return e.replace(/[^A-Za-z0-9]+/g,"_").replace(/^_+|_+$/g,"")}function Oj(e){let t=new Map;return e.map(r=>{let n=Fj(r)||"row",o=t.get(n)??0;return t.set(n,o+1),o===0?n:`${n}_${o+1}`})}async function wN(e){let t=(await bN([e])).get(e);if(!t)return;let r=EN(await zt(Rl(`${Dy}/efetch.fcgi?db=protein&id=${t}&rettype=fasta&retmode=text`))).get(t);return r?{accession:t,sequence:r}:void 0}async function IN({geneId:e,taxa:t,onProgress:r}){r("Finding orthologs across species...");let n=await Pj(e,t);if(n.length<2)throw new Error(`Only ${n.length} ortholog(s) found among the selected species \u2014 not enough to align`);r("Selecting a representative protein per species...");let o=await bN(n.map(u=>u.geneId)),i=n.filter(u=>o.has(u.geneId));if(i.length<2)throw new Error("Could not resolve representative proteins for the orthologs");r(`Fetching ${i.length} protein sequences...`);let s=i.map(u=>o.get(u.geneId)),a=EN(await zt(Rl(`${Dy}/efetch.fcgi?db=protein&id=${s.join(",")}&rettype=fasta&retmode=text`))),c=Oj(i.map(u=>u.commonName??u.scientificName)),l=i.map((u,d)=>{let A=o.get(u.geneId);return{taxId:u.taxId,label:c[d],scientificName:u.scientificName,commonName:u.commonName,geneId:u.geneId,protein:A,sequence:a.get(A)??""}}).filter(u=>u.sequence);if(l.length<2)throw new Error("Could not fetch protein sequences for the orthologs");return l}async function SN({self:e}){let{taxId:t,taxa:r,geneCandidates:n,msaAlgorithm:o,proteinSequence:i}=e.orthologParams,s=h=>{e.setProgress(h)};s("Resolving gene at NCBI...");let a=await CN(n,t);if(!a)throw new Error(`Could not resolve any of ${n.join(", ")} to an NCBI gene in taxon ${t}. Try the NCBI BLAST tab, which needs no gene identifier.`);let c=await Gj(a.geneId),l=i?Ra(i):c?.sequence;if(!l)throw new Error(`No query protein: none was supplied and NCBI returned no representative protein for gene ${a.geneId}.`);let u=r??ji.map(h=>h.taxId),d=new Set(u.filter(h=>h!==t)),A=await IN({geneId:a.geneId,taxa:d,onProgress:s}),f={QUERY:Uj(e,a.geneId,l,c)};for(let h of A)f[h.label]=Hj(h);return{...await mA({algorithm:o,sequence:[`>QUERY
-${l}`,...A.map(h=>`>${h.label}
+                           .**: ****: ** ***.***`,nD="(((UniProt/Swiss-Prot|P26898|IL2RA_SHEEP:0.24036,(UniProt/Swiss-Prot|P41690|IL2RA_FELCA:0.17737,(UniProt/Swiss-Prot|P01589|IL2RA_HUMAN:0.03906,UniProt/Swiss-Prot|Q5MNY4|IL2RA_MACMU:0.03787):0.13033):0.04964):0.02189,UniProt/Swiss-Prot|P01590|IL2RA_MOUSE:0.23072):0.06814,(((UniProt/Swiss-Prot|Q95118|IL2RG_BOVIN:0.09600,UniProt/Swiss-Prot|P40321|IL2RG_CANFA:0.09845):0.25333,UniProt/Swiss-Prot|Q29416|IL2_CANFA:-0.35055):0.10231,(UniProt/Swiss-Prot|P26896|IL2RB_RAT:0.33631,UniProt/Swiss-Prot|Q7JFM4|IL2_AOTVO:-0.33631):0.10166):0.01607,(UniProt/Swiss-Prot|Q8BZM1|GLMN_MOUSE:0.32378,UniProt/Swiss-Prot|P36835|IL2_CAPHI:-0.32378):0.09999)"});function cA(e,t,r,n){e.setError(void 0),t&&e.setMSAFilehandle(t),r&&e.setTreeFilehandle(r),n&&e.setGFFFilehandle(n)}var xy=m(()=>{});function Bn({onClick:e,model:t,children:r}){return Yt.default.createElement("li",null,Yt.default.createElement(lA.Link,{onClick:n=>{t.setError(void 0),n.preventDefault(),e()},href:"#"},Yt.default.createElement(lA.Typography,{component:"span"},r)))}var Yt,lA,iD,Go,aj,sD,aD=m(()=>{Yt=p(Q(),1),lA=p(U(),1),iD=p(Y(),1);oD();xy();Go="https://jbrowse.org/genomes/multiple_sequence_alignments",aj=(0,iD.observer)(function({model:e}){function t({msa:r,tree:n,gff:o}){try{cA(e,r?{uri:r,locationType:"UriLocation"}:void 0,n?{uri:n,locationType:"UriLocation"}:void 0,o?{uri:o,locationType:"UriLocation"}:void 0)}catch(i){console.error(i),e.setError(i)}}return Yt.default.createElement("ul",null,Yt.default.createElement(Bn,{model:e,onClick:()=>{t({tree:"https://jbrowse.org/genomes/newicktrees/sarscov2phylo.pub.ft.nh"})}},"230k COVID-19 samples (tree only)"),Yt.default.createElement(Bn,{model:e,onClick:()=>{e.setData({msa:tD,tree:nD})}},"Small protein MSA+tree"),Yt.default.createElement(Bn,{model:e,onClick:()=>{e.setData({msa:rD})}},"Small MSA only"),Yt.default.createElement(Bn,{model:e,onClick:()=>{t({msa:`${Go}/pfam-cov2.stock`})}},"PFAM SARS-CoV2 multi-stockholm"),Yt.default.createElement(Bn,{model:e,onClick:()=>{t({msa:`${Go}/pfam-cov2.stock`,gff:`${Go}/pfam-cov2-domains.gff`})}},"PFAM SARS-CoV2 multi-stockholm w/ domains loaded"),Yt.default.createElement(Bn,{model:e,onClick:()=>{t({msa:`${Go}/Lysine.stock`})}},"Lysine stockholm file"),Yt.default.createElement(Bn,{model:e,onClick:()=>{t({msa:`${Go}/PF01601_full.txt`})}},"PF01601 stockholm file (SARS-CoV2 spike protein)"),Yt.default.createElement(Bn,{model:e,onClick:()=>{t({msa:`${Go}/europe_covid.fa`})}},"Europe COVID full genomes (LR883044.1 and 199 other sequences)"),Yt.default.createElement(Bn,{model:e,onClick:()=>{t({msa:`${Go}/rhv_test-only.aligned_with_mafft_auto.fa`,tree:`${Go}/rhv_test-only.aligned_with_mafft_auto.nh`})}},"MAFFT+VeryFastTree(17.9k samples)"),Yt.default.createElement(Bn,{model:e,onClick:()=>{t({msa:"https://jbrowse.org/demos/ttc39a.mfa"})}},"Human BLAST results mfa"))}),sD=aj});var Ie,Sa,Yr,cD,cj,lD,uD=m(()=>{Ie=p(Q(),1),Sa=p(Xe(),1),Yr=p(U(),1),cD=p(Y(),1);aD();xy();cj=(0,cD.observer)(function({model:e}){let[t,r]=(0,Ie.useState)(),[n,o]=(0,Ie.useState)(),[i,s]=(0,Ie.useState)(),{error:a}=e;return Ie.default.createElement(Yr.Container,null,Ie.default.createElement("div",{style:{width:"50%"}},a?Ie.default.createElement(Sa.ErrorMessage,{error:a}):null,Ie.default.createElement(Yr.Typography,null,"Open an MSA file (stockholm or clustal format) and/or a tree file (newick format)."),Ie.default.createElement(Yr.Typography,{color:"error"},"Note: you can open up just an MSA or just a tree, both are not required. Some MSA files e.g. stockholm format have an embedded tree also and this is fine, and opening a separate tree file is not required.")),Ie.default.createElement("div",{style:{display:"flex",justifyContent:"center",alignItems:"center",gap:40}},Ie.default.createElement("div",null,Ie.default.createElement("div",null,Ie.default.createElement(Yr.Typography,null,"MSA file or URL"),Ie.default.createElement(Sa.FileSelector,{location:t,setLocation:r})),Ie.default.createElement("div",null,Ie.default.createElement(Yr.Typography,null,"Tree file or URL"),Ie.default.createElement(Sa.FileSelector,{location:n,setLocation:o})),Ie.default.createElement("div",null,Ie.default.createElement(Yr.Typography,null,"InterProScan GFF file or URL (optional)"),Ie.default.createElement(Sa.FileSelector,{location:i,setLocation:s}))),Ie.default.createElement("div",null,Ie.default.createElement(Yr.Button,{onClick:()=>{try{cA(e,t,n,i)}catch(c){console.error(c),e.setError(c)}},variant:"contained",color:"primary",disabled:!t&&!n},"Open")),Ie.default.createElement("div",null,Ie.default.createElement(Yr.Typography,null,"Examples"),Ie.default.createElement(sD,{model:e}))))}),lD=cj});var At,dD,Rl,uA,fD,lj,uj,fA,Cy=m(()=>{At=p(Q(),1),dD=p(Xe(),1);Eg();Rl=p(U(),1),uA=p(Y(),1);eD();uD();fD=(0,uA.observer)(function({model:e}){let{status:t}=e;return At.default.createElement("div",{style:{display:"flex",alignItems:"center",gap:12,padding:20}},At.default.createElement("svg",{width:"24",height:"24",viewBox:"0 0 24 24",xmlns:"http://www.w3.org/2000/svg"},At.default.createElement("style",null,"@keyframes spinner { to { transform: rotate(360deg); } }"),At.default.createElement("circle",{cx:"12",cy:"12",r:"10",stroke:"#ccc",strokeWidth:"3",fill:"none"}),At.default.createElement("path",{d:"M12 2a10 10 0 0 1 10 10",stroke:"#1976d2",strokeWidth:"3",fill:"none",strokeLinecap:"round",style:{animation:"spinner 1s linear infinite",transformOrigin:"center"}})),At.default.createElement(Rl.Typography,{variant:"h6"},t?.msg??"Loading..."),t?.onCancel?At.default.createElement(Rl.Button,{variant:"outlined",size:"small",onClick:()=>t.onCancel?.()},"Cancel"):null)}),lj=(0,uA.observer)(function({model:e,error:t}){return At.default.createElement("div",null,At.default.createElement(dD.ErrorMessage,{error:t}),At.default.createElement(Rl.Button,{variant:"contained",color:"primary",onClick:()=>{e.reset()}},"Return to import form"))}),uj=(0,uA.observer)(function({model:e}){let{isLoading:t,dataInitialized:r,msaFilehandle:n,treeFilehandle:o}=e,i=!!(n||o);return At.default.createElement("div",null,At.default.createElement(Hs,{FallbackComponent:s=>At.default.createElement(lj,{model:e,error:s.error})},r?t?At.default.createElement(fD,{model:e}):At.default.createElement(Zk,{model:e}):i||t?At.default.createElement(fD,{model:e}):At.default.createElement(lD,{model:e})))}),fA=uj});var mD=X((xme,AD)=>{AD.exports=JBrowseExports["@jbrowse/core/ui/theme"]});var Ey=X((Cme,pD)=>{pD.exports=JBrowseExports["@jbrowse/core/util/io"]});var hD=X((Eme,gD)=>{gD.exports=JBrowseExports["@jbrowse/core/util/types/mst"]});function by({mapSize:e,blockSize:t,viewportPos:r,viewportSize:n}){let o=Math.max(0,Math.min(r,e-n)),i=Math.floor(o/t),s=Math.floor((o+n-1)/t),a=[];for(let c=i;c<=s;c++)a.push(c*t);return a}var yD=m(()=>{});function wD(e,t){let r=e.total(t),n=G=>e.count(t,G),o=n("W"),i=n("L"),s=n("V"),a=n("I"),c=n("M"),l=n("A"),u=n("F"),d=n("C"),A=n("H"),f=n("P"),g=n("R"),h=n("K"),x=n("Q"),w=n("E"),y=n("D"),v=n("T"),b=n("S"),I=n("G"),S=n("Y"),B=n("N"),R=o+i+s+a+c+l+u+d+A+f+S,D=h+g,L=x+w,P=w+y,C=v+b,M=G=>G/r,k={};return M(R)>.6&&(k.W=Uo,k.L=Uo,k.V=Uo,k.A=Uo,k.I=Uo,k.M=Uo,k.F=Uo,k.C=Uo),(M(D)>.6||M(h)>.8||M(g)>.8||M(x)>.8)&&(k.K=xD,k.R=xD),(M(D)>.6||M(L)>.5||M(w)>.8||M(x)>.8||M(y)>.8)&&(k.E=fj),(M(D)>.6||M(P)>.5||M(h)>.8||M(g)>.8||M(x)>.8)&&(k.D=dj),(M(B)>.5||M(S)>.85)&&(k.N=CD),(M(D)>.6||M(L)>.6||M(x)>.85||M(w)>.85||M(h)>.85||M(g)>.85)&&(k.Q=CD),(M(R)>.6||M(C)>.5||M(b)>.85||M(v)>.85)&&(k.S=ED,k.T=ED),M(d)>.85&&(k.C=Aj),I>0&&(k.G=mj),f>0&&(k.P=pj),(M(R)>.6||M(o)>.85||M(S)>.85||M(l)>.85||M(d)>.85||M(f)>.85||M(x)>.85||M(u)>.85||M(A)>.85||M(a)>.85||M(i)>.85||M(c)>.85||M(s)>.85)&&(k.H=bD,k.Y=bD),k}var Uo,xD,fj,dj,CD,ED,Aj,mj,pj,bD,ID=m(()=>{Uo="rgb(128,179,230)",xD="#d88",fj="rgb(192, 72, 192)",dj="rgb(204, 77, 204)",CD="#8f8",ED="rgb(26,204,26)",Aj="rgb(240, 128, 128)",mj="rgb(240, 144, 72)",pj="rgb(204, 204, 0)",bD="rgb(26, 179, 179)"});function dA(e){return e<128?va[e]:30}function SD(e){return e===27||e===28}function vD(e){return Oi[e]}function BD(e){return dA(e.charCodeAt(0))}function MD(e){let t=e.reduce((n,o)=>Math.max(n,o.length),0),r=new wy(t);for(let n of e)r.addRow(n);return r}var va,Oi,wy,TD,Iy=m(()=>{va=new Uint8Array(128).fill(30);for(let e=65;e<=90;e++)va[e]=e-65+1;for(let e=97;e<=122;e++)va[e]=e-97+1;va[45]=27;va[46]=28;va[42]=29;Oi=Array.from({length:32},(e,t)=>t>=1&&t<=26?String.fromCharCode(65+t-1):"");Oi[27]="-";Oi[28]=".";Oi[29]="*";Oi[30]="?";wy=class{numColumns;counts;totals;slotTotals=new Uint32Array(32);constructor(t){this.numColumns=t,this.counts=new Uint32Array(t*32),this.totals=new Uint32Array(t)}addRow(t){let{counts:r,totals:n,slotTotals:o}=this,i=Math.min(t.length,this.numColumns);for(let s=0;s<i;s++){let a=dA(t.charCodeAt(s));r[s*32+a]++,n[s]++,o[a]++}}add(t,r){let n=dA(r.charCodeAt(0));this.counts[t*32+n]++,this.totals[t]++,this.slotTotals[n]++}total(t){return this.totals[t]??0}count(t,r){return this.counts[t*32+dA(r.charCodeAt(0))]??0}gapCount(t){let r=t*32;return(this.counts[r+27]??0)+(this.counts[r+28]??0)}forEachResidue(t,r){let{counts:n}=this,o=t*32;for(let i=1;i<32;i++){let s=n[o+i];s>0&&!SD(i)&&r(i,s)}}residueEntries(t){let r=[];return this.forEachResidue(t,(n,o)=>{r.push([Oi[n],o])}),r}get lettersPresent(){let t=new Set;for(let r=1;r<32;r++)this.slotTotals[r]>0&&!SD(r)&&t.add(Oi[r]);return t}};TD=32});var Ql,Sy,gj,hj,vy,RD=m(()=>{Ql=p(Q(),1),Sy=p(Y(),1);Fi();Ig();xf();gj=(0,Sy.observer)(function({model:e,track:t,offsetX:r,trackHeight:n}){let{blockSize:o,scrollX:i,highResScaleFactor:s}=e,a=Mr(c=>{let{blockSize:l,colWidth:u,highResScaleFactor:d}=e;c.resetTransform(),c.scale(d,d),c.clearRect(0,0,l,n),c.translate(-r,0),ag({ctx:c,values:cg(e,t.model.id),color:t.model.barColor??"gray",colWidth:u,trackHeight:n,offsetX:r,blockSize:l})},[e,t,r,n]);return Ql.default.createElement("canvas",{ref:a,height:n*s,width:o*s,style:{position:"absolute",left:i+r,width:o,height:n}})}),hj=(0,Sy.observer)(function({model:e,track:t}){let{blocksX:r,msaAreaWidth:n}=e,o=t.model.height;return Ql.default.createElement("div",{style:{position:"relative",height:o,width:n,overflow:"hidden"}},r.map(i=>Ql.default.createElement(gj,{key:i,model:e,track:t,offsetX:i,trackHeight:o})),Ql.default.createElement(iS,{model:e}))}),vy=hj});var AA,By,yj,xj,QD,_D=m(()=>{AA=p(Q(),1),By=p(Y(),1);Os();Fi();my();xf();yj=(0,By.observer)(function({track:e,model:t,offsetX:r}){let{blockSize:n,scrollX:o,colorScheme:i,rowHeight:s,highResScaleFactor:a}=t,{model:{customColorScheme:c,data:l}}=e,u=c??i,{theme:d,contrastScheme:A}=oA(u),f=Mr(g=>{let{blockSize:h,bgColor:x,colWidth:w,fontSize:y,rowHeight:v,highResScaleFactor:b}=t;g.resetTransform(),g.scale(b,b),g.clearRect(0,0,h,v),g.translate(-r,0),g.textAlign="center",pn(g,y),lg({ctx:g,data:l,colorScheme:u,contrastScheme:A,bgColor:x,textColor:d.palette.text.primary,colWidth:w,rowHeight:v,offsetX:r,blockSize:h})},[t,r,d,A,u,l]);return AA.default.createElement("canvas",{ref:f,height:s*a,width:n*a,style:{position:"absolute",left:o+r,width:n,height:s}})}),xj=(0,By.observer)(function({track:e,model:t}){let{blocksX:r,msaAreaWidth:n,rowHeight:o}=t;return e.model.data?AA.default.createElement("div",{style:{position:"relative",height:o,width:n,overflow:"hidden"}},r.map(i=>AA.default.createElement(yj,{key:i,track:e,model:t,offsetX:i}))):null}),QD=xj});var Cj,Ty,kD=m(()=>{Cj=[["#F8766D"],["#F8766D","#00BFC4"],["#F8766D","#00BA38","#619CFF"],["#F8766D","#7CAE00","#00BFC4","#C77CFF"],["#F8766D","#A3A500","#00BF7D","#00B0F6","#E76BF3"],["#F8766D","#B79F00","#00BA38","#00BFC4","#619CFF","#F564E3"],["#F8766D","#C49A00","#53B400","#00C094","#00B6EB","#A58AFF","#FB61D7"],["#F8766D","#CD9600","#7CAE00","#00BE67","#00BFC4","#00A9FF","#C77CFF","#FF61CC"]],Ty=Cj});function DD(e){let t=e.length;if(t<=Ty.length){let r=Ty[t-1];return Object.fromEntries(e.map((n,o)=>[n,r[o]]))}return Object.fromEntries(e.map((r,n)=>[r,it({h:n*360/t,s:60,l:60}).toHex()]))}var ND=m(()=>{Mc();kD()});function LD(e){let t=new Map(e.map(n=>{let o=n.dist===void 0?void 0:Number(n.dist);return[n.id,{id:`${n.id}`,name:n.label||`${n.id}`,...o!==void 0&&Number.isFinite(o)?{length:o}:{},children:[]}]})),r;for(let n of e){let o=t.get(n.id),i=n.parent!==void 0?t.get(n.parent):void 0;i?i.children.push(o):r??=o}if(r===void 0)throw new Error("could not build tree from flat node list: no root found (input was empty or contains a parent cycle)");return r}var FD=m(()=>{});function PD(e,t){My||(My=document.createElement("canvas"));let r=My.getContext("2d");if(!r)throw new Error("no canvas context");return pn(r,t),r.measureText(e).width}var My,OD=m(()=>{Os()});function GD(){return Tn.types.model({tree:Tn.types.maybe(Tn.types.string),msa:Tn.types.maybe(Tn.types.string),treeMetadata:Tn.types.maybe(Tn.types.string),gff:Tn.types.maybe(Tn.types.string)}).actions(e=>({setTree(t){e.tree=t},setMSA(t){e.msa=t},setTreeMetadata(t){e.treeMetadata=t},setGFF(t){e.gff=t}})).postProcessSnapshot(e=>{let{tree:t,msa:r,treeMetadata:n,gff:o}=e,i=5e4;return{tree:t&&t.length>i?void 0:t,msa:r&&r.length>i?void 0:r,treeMetadata:n&&n.length>i?void 0:n,gff:o&&o.length>i?void 0:o}})}var Tn,UD=m(()=>{Tn=p(zt(),1)});function VD(){return HD.types.model("DialogQueueSessionMixin",{}).volatile(()=>({queueOfDialogs:[]})).views(e=>({get DialogComponent(){return e.queueOfDialogs[0]?.[0]},get DialogProps(){return e.queueOfDialogs[0]?.[1]}})).actions(e=>({removeActiveDialog(){e.queueOfDialogs=e.queueOfDialogs.slice(1)},queueDialog(t){let[r,n]=t(()=>{this.removeActiveDialog()});e.queueOfDialogs=[...e.queueOfDialogs,[r,n]]}}))}var HD,jD=m(()=>{HD=p(zt(),1)});function fe(e,t){return typeof mA.types.stripDefault=="function"?mA.types.stripDefault(e,t):mA.types.optional(e,t)}var mA,pA=m(()=>{mA=p(zt(),1)});function $D(){return Gi.types.model({bgColor:fe(Gi.types.boolean,cI),colorSchemeName:fe(Gi.types.string,ff),showColumnStats:fe(Gi.types.boolean,lI),msaFormat:Gi.types.maybe(Gi.types.enumeration("MSAFormat",Ej))}).actions(e=>({setColorSchemeName(t){e.colorSchemeName=t},setBgColor(t){e.bgColor=t},setShowColumnStats(t){e.showColumnStats=t},setMSAFormat(t){e.msaFormat=t}}))}var Gi,Ej,WD=m(()=>{Gi=p(zt(),1);Bc();pA();Ej=["stockholm","a3m","fasta","emf","clustal"]});function YD(){return Mn.types.model({drawLabels:fe(Mn.types.boolean,uI),labelsAlignRight:fe(Mn.types.boolean,fI),treeAreaWidth:fe(Mn.types.number,dI),treeWidth:fe(Mn.types.number,AI),showBranchLen:fe(Mn.types.boolean,mI),drawTree:fe(Mn.types.boolean,pI),drawNodeBubbles:fe(Mn.types.boolean,gI),autoTreeAreaWidth:fe(Mn.types.boolean,!1)}).actions(e=>({setTreeAreaWidth(t){e.treeAreaWidth=Math.round(t)},setTreeWidth(t){e.treeWidth=Math.round(t)},setLabelsAlignRight(t){e.labelsAlignRight=t},setDrawTree(t){e.drawTree=t},setAutoTreeAreaWidth(t){e.autoTreeAreaWidth=t},setShowBranchLen(t){e.showBranchLen=t},setDrawNodeBubbles(t){e.drawNodeBubbles=t},setDrawLabels(t){e.drawLabels=t}}))}var Mn,qD=m(()=>{Mn=p(zt(),1);Bc();pA()});function Ry(e,t){return KD.get(e.toUpperCase())?.get(t.toUpperCase())??-4}function zD(e){return e==="-"||e==="."}function wj(e,t){if(e.length!==t.length)throw new Error("Sequences must have the same length (aligned)");let r=0,n=0,o=0,i=0;for(let l=0;l<e.length;l++){let u=e[l],d=t[l],A=zD(u),f=zD(d);if(A&&f)continue;if(A||f){n++;continue}let g=Ry(u,d);o+=g,i+=Math.max(Ry(u,u),Ry(d,d)),u.toUpperCase()===d.toUpperCase()?r++:n++}if(r+n===0||i<=0)return 1;let a=o/i,c=Math.max(.01,Math.min(1,a));return-Math.log(c)}function Ij(e){let t=e.length,r=[];for(let n=0;n<t;n++){r[n]=[];for(let o=0;o<t;o++)n===o?r[n][o]=0:o<n?r[n][o]=r[o][n]:r[n][o]=wj(e[n][1],e[o][1])}return r}function Sj(e,t){let r=e.length;if(r<2)return{name:t[0]};if(r===2){let a=e[0][1];return{left:{name:t[0]},right:{name:t[1]},leftLength:a/2,rightLength:a/2}}let n=[];for(let a=0;a<r;a++)n[a]=[...e[a]];let o=t.map(a=>({name:a})),i=r;for(;i>2;){let a=[];for(let y=0;y<o.length;y++)o[y]!==void 0&&a.push(y);let c=new Map;for(let y of a){let v=0;for(let b of a)y!==b&&(v+=n[y][b]);c.set(y,v)}let l=1/0,u=-1,d=-1;for(let y=0;y<a.length;y++)for(let v=y+1;v<a.length;v++){let b=a[y],I=a[v],S=(i-2)*n[b][I]-c.get(b)-c.get(I);S<l&&(l=S,u=b,d=I)}let A=n[u][d],f=c.get(u),g=c.get(d),h=A/2+(f-g)/(2*(i-2)),x=A-h;h=Math.max(0,h),x=Math.max(0,x);let w={left:o[u],right:o[d],leftLength:h,rightLength:x};for(let y of a)if(y!==u&&y!==d){let v=(n[u][y]+n[d][y]-A)/2;n[u][y]=Math.max(0,v),n[y][u]=Math.max(0,v)}o[d]=void 0,o[u]=w,i--}let s=[];for(let a=0;a<o.length;a++)o[a]!==void 0&&s.push(a);if(s.length===2){let a=s[0],c=s[1],l=n[a][c];return{left:o[a],right:o[c],leftLength:l/2,rightLength:l/2}}return o[s[0]]}function JD(e,t){return t===void 0?e:`${e}:${t.toFixed(6)}`}function vj(e){let t=[],r=[e];for(;r.length>0;){let o=r.pop();t.push(o),o.left&&r.push(o.left),o.right&&r.push(o.right)}let n=new Map;for(let o=t.length-1;o>=0;o--){let i=t[o];if(i.name!==void 0&&!i.left&&!i.right)n.set(i,`'${i.name.replaceAll("'","''")}'`);else{let s=i.left?JD(n.get(i.left),i.leftLength):"",a=i.right?JD(n.get(i.right),i.rightLength):"";n.set(i,`(${s},${a})`)}}return n.get(e)}function XD(e){if(e.length<2)throw new Error("Need at least 2 sequences to build a tree");let t=e.map(o=>o[0]),r=Ij(e),n=Sj(r,t);return vj(n)+";"}var gA,bj,KD,ZD=m(()=>{gA="ARNDCQEGHILKMFPSTWYVBZX*",bj=[[4,-1,-2,-2,0,-1,-1,0,-2,-1,-1,-1,-1,-2,-1,1,0,-3,-2,0,-2,-1,0,-4],[-1,5,0,-2,-3,1,0,-2,0,-3,-2,2,-1,-3,-2,-1,-1,-3,-2,-3,-1,0,-1,-4],[-2,0,6,1,-3,0,0,0,1,-3,-3,0,-2,-3,-2,1,0,-4,-2,-3,3,0,-1,-4],[-2,-2,1,6,-3,0,2,-1,-1,-3,-4,-1,-3,-3,-1,0,-1,-4,-3,-3,4,1,-1,-4],[0,-3,-3,-3,9,-3,-4,-3,-3,-1,-1,-3,-1,-2,-3,-1,-1,-2,-2,-1,-3,-3,-2,-4],[-1,1,0,0,-3,5,2,-2,0,-3,-2,1,0,-3,-1,0,-1,-2,-1,-2,0,3,-1,-4],[-1,0,0,2,-4,2,5,-2,0,-3,-3,1,-2,-3,-1,0,-1,-3,-2,-2,1,4,-1,-4],[0,-2,0,-1,-3,-2,-2,6,-2,-4,-4,-2,-3,-3,-2,0,-2,-2,-3,-3,-1,-2,-1,-4],[-2,0,1,-1,-3,0,0,-2,8,-3,-3,-1,-2,-1,-2,-1,-2,-2,2,-3,0,0,-1,-4],[-1,-3,-3,-3,-1,-3,-3,-4,-3,4,2,-3,1,0,-3,-2,-1,-3,-1,3,-3,-3,-1,-4],[-1,-2,-3,-4,-1,-2,-3,-4,-3,2,4,-2,2,0,-3,-2,-1,-2,-1,1,-4,-3,-1,-4],[-1,2,0,-1,-3,1,1,-2,-1,-3,-2,5,-1,-3,-1,0,-1,-3,-2,-2,0,1,-1,-4],[-1,-1,-2,-3,-1,0,-2,-3,-2,1,2,-1,5,0,-2,-1,-1,-1,-1,1,-3,-1,-1,-4],[-2,-3,-3,-3,-2,-3,-3,-3,-1,0,0,-3,0,6,-4,-2,-2,1,3,-1,-3,-3,-1,-4],[-1,-2,-2,-1,-3,-1,-1,-2,-2,-3,-3,-1,-2,-4,7,-1,-1,-4,-3,-2,-2,-1,-2,-4],[1,-1,1,0,-1,0,0,0,-1,-2,-2,0,-1,-2,-1,4,1,-3,-2,-2,0,0,0,-4],[0,-1,0,-1,-1,-1,-1,-2,-2,-1,-1,-1,-1,-2,-1,1,5,-2,-2,0,-1,-1,0,-4],[-3,-3,-4,-4,-2,-2,-3,-2,-2,-3,-2,-3,-1,1,-4,-3,-2,11,2,-3,-4,-3,-2,-4],[-2,-2,-2,-3,-2,-1,-2,-3,2,-1,-1,-2,-1,3,-3,-2,-2,2,7,-1,-3,-2,-1,-4],[0,-3,-3,-3,-1,-2,-2,-3,-3,3,1,-2,1,-1,-2,-2,0,-3,-1,4,-3,-2,-1,-4],[-2,-1,3,4,-3,0,1,-1,0,-3,-4,0,-3,-3,-2,0,-1,-4,-3,-3,4,1,-1,-4],[-1,0,0,1,-3,3,4,-2,0,-3,-3,1,-1,-3,-1,0,-1,-3,-2,-2,1,4,-1,-4],[0,-1,-1,-1,-2,-1,-1,-1,-1,-1,-1,-1,-1,-1,-2,0,0,-2,-1,-1,-1,-1,-1,-4],[-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,1]],KD=new Map;for(let e=0;e<gA.length;e++){let t=new Map;for(let r=0;r<gA.length;r++)t.set(gA[r],bj[e][r]);KD.set(gA[e],t)}});function Qy(e){let t=[],r=0;for(;r<e.length&&(r=e.indexOf("{",r),r!==-1);){let n=1,o=r+1;for(r++;r<e.length&&n>0;)e[r]==="{"?n++:e[r]==="}"&&n--,r++;n===0&&t.push(e.slice(o,r-1).trim())}return t}function Tj(e,t){let r=e.indexOf("{",t);if(r===-1)return;let n=1,o=r+1;for(;o<e.length&&n>0;)e[o]==="{"?n++:e[o]==="}"&&n--,o++;return n===0?e.slice(r+1,o-1).trim():void 0}function eN(e){let t=e.replace(/\s+/g," ").replace(/\s*{\s*/g,"{").replace(/\s*}\s*/g,"}").replace(/\s*,\s*/g,",").replace(/\s*::\s*=\s*/g,"::=").replace(/^.*?::=/,""),r=Mj(t),{fdict:n,nodes:o}=r;if(n===void 0||o===void 0)throw new Error(`invalid BioTreeContainer ASN.1: missing '${n===void 0?"fdict":"nodes"}' section`);let i=Object.fromEntries(Qy(n).flatMap(s=>{let a=Rj(s);return a?[[a.id,Bj[a.name]||a.name]]:[]}));return Qy(o).flatMap(s=>{let a=Qj(s);if(!a)return[];let{features:c=[],...l}=a;return[{...l,...Object.fromEntries(c.map(u=>[i[u.featureid],u.value]))}]})}function Mj(e){let t={},r=e.trim();r.startsWith("{")&&r.endsWith("}")&&(r=r.slice(1,-1).trim());let n=0;for(;n<r.length;){for(;n<r.length&&/\s/.test(r[n]);)n++;if(n>=r.length)break;let o=n;for(;n<r.length&&/\w/.test(r[n]);)n++;if(n>=r.length||r[n]!==" "&&r[n]!=="{"){n=r.indexOf(",",n),n=n===-1?r.length:n+1;continue}let i=r.slice(o,n).trim();for(;n<r.length&&/\s/.test(r[n]);)n++;if(n>=r.length||r[n]!=="{"){n=r.indexOf(",",n),n=n===-1?r.length:n+1;continue}let s=1,a=n+1;for(n++;n<r.length&&s>0;)r[n]==="{"?s++:r[n]==="}"&&s--,n++;s===0&&(t[i]=r.slice(a,n-1).trim()),n=r.indexOf(",",n),n=n===-1?r.length:n+1}return t}function Rj(e){let t=/id\s+(\d+)/.exec(e),r=/name\s+"((?:[^"\\]|\\.)*)"/s.exec(e);return!t||!r?null:{id:parseInt(t[1],10),name:r[1].replace(/\\"/g,'"').replace(/\\\\/g,"\\")}}function Qj(e){let t=/id\s+(\d+)/.exec(e);if(!t)return null;let r=/parent\s+(\d+)/.exec(e),n=e.indexOf("features"),o=n!==-1?Tj(e,n):void 0;return{id:parseInt(t[1],10),...r?{parent:parseInt(r[1],10)}:{},features:o?Qy(o).flatMap(i=>{let s=_j(i);return s?[s]:[]}):[]}}function _j(e){let t=/featureid\s+(\d+)/.exec(e),r=/value\s+"((?:[^"\\]|\\.)*)"/s.exec(e);return!t||!r?null:{featureid:parseInt(t[1],10),value:r[1].replace(/\\"/g,'"').replace(/\\\\/g,"\\")}}var Bj,tN=m(()=>{Bj={$NODE_COLLAPSED:"collapsed",$NODE_COLOR:"color",$LABEL_BG_COLOR:"color","seq-id":"seqId","seq-title":"seqTitle","align-index":"alignIndex","accession-nbr":"accessionNbr","blast-name":"blastName","common-name":"commonName","leaf-count":"leafCount"}});function oN(e){let t=new Float64Array(_y.length);return Array.from({length:e.numColumns},(r,n)=>{let o=e.total(n),i=0;if(o){t.fill(0);let s=0;if(e.forEachResidue(n,(a,c)=>{let l=nN[a];l>=0&&(t[l]+=c,s+=c)}),s>0){let a=0;for(let l of t)if(l>0){let u=l/s;a-=u*Math.log2(u)}let c=(o-s)/o;i=Math.max(0,1-a/kj)*(1-c)}}return i})}var rN,_y,kj,nN,iN=m(()=>{Iy();rN={A:"hydrophobic",V:"hydrophobic",L:"hydrophobic",I:"hydrophobic",M:"hydrophobic",C:"hydrophobic",F:"aromatic",W:"aromatic",Y:"aromatic",H:"aromatic",K:"positive",R:"positive",D:"negative",E:"negative",S:"polar",T:"polar",N:"polar",Q:"polar",G:"special",P:"special"},_y=[...new Set(Object.values(rN))],kj=Math.log2(_y.length),nN=new Int8Array(TD).fill(-1);for(let[e,t]of Object.entries(rN))nN[BD(e)]=_y.indexOf(t)});function ky(e,t){let r=0,n=0,o=0,i=e.length;for(;n<i&&e[n]===o;)n++,o++;for(;r<t;)for(r++,o++;n<i&&e[n]===o;)n++,o++;return o}function sN(e,t){let r=0,n=e.length-1;for(;r<=n;){let i=Math.floor((r+n)/2);if(e[i]===t)return;e[i]<t?r=i+1:n=i-1}return t-r}function Dj({seq:e,blanks:t,visibleCol:r}){let n=ky(t,r),o=e.length;if(n<o&&hf(e[n]))return;let i=0;for(let s=0;s<n&&s<o;s++)hf(e[s])||i++;return n<o?i:void 0}function aN({rowName:e,visibleCol:t,rowMap:r,blanks:n}){let o=r.get(e);return o!==void 0?Dj({seq:o,visibleCol:t,blanks:n}):void 0}var cN=m(()=>{ho()});function lN(e){let t=new Int32Array(e.length),r=0;for(let n=0;n<e.length;n++)e.charCodeAt(n)-45>>>0<=1||(t[r++]=n);return t.subarray(0,r)}var uN=m(()=>{ho()});function fN(e,t){let r=URL.createObjectURL(e),n=document.createElement("a");n.href=r,n.download=t,n.click(),setTimeout(()=>{URL.revokeObjectURL(r)},4e4)}var dN=m(()=>{});function jj(e){return e.startsWith("BioTreeContainer")?LD(eN(e)):Mi(e.startsWith("SEQ")?bd(e).tree:e)}function $j(){return J.types.compose(VD(),YD(),$D(),J.types.model("MsaView",{id:Ui.ElementId,showDomains:fe(J.types.boolean,!1),showDomainLegend:fe(J.types.boolean,!0),hideGaps:fe(J.types.boolean,!0),allowedGappyness:fe(J.types.number,100),subFeatureRows:fe(J.types.boolean,!1),type:J.types.literal("MsaView"),drawMsaLetters:fe(J.types.boolean,sI),scrollZoom:fe(J.types.boolean,aI),height:fe(J.types.number,550),rowHeight:fe(J.types.number,16),scrollY:fe(J.types.number,0),scrollX:fe(J.types.number,0),colWidth:fe(J.types.number,12),treeFilehandle:J.types.maybe(Ui.FileLocation),msaFilehandle:J.types.maybe(Ui.FileLocation),treeMetadataFilehandle:J.types.maybe(Ui.FileLocation),gffFilehandle:J.types.maybe(Ui.FileLocation),currentAlignment:fe(J.types.number,0),collapsed:fe(J.types.array(J.types.string),[]),showOnly:J.types.maybe(J.types.string),turnedOffTracks:fe(J.types.map(J.types.boolean),{}),data:J.types.optional(GD(),{tree:"",msa:"",treeMetadata:""}),featureFilters:fe(J.types.map(J.types.boolean),{}),relativeTo:J.types.maybe(J.types.string),highlightColumns:J.types.frozen()})).volatile(()=>({headerHeight:0,status:void 0,highResScaleFactor:typeof window>"u"?1:window.devicePixelRatio,loadingMSA:!1,loadingTree:!1,volatileWidth:void 0,resizeHandleWidth:5,blockSize:500,mouseRow:void 0,mouseCol:void 0,mouseClickRow:void 0,mouseClickCol:void 0,hoveredTreeNode:void 0,highlightedColumns:void 0,minimapHeight:56,conservationTrackHeight:40,marginLeft:20,error:void 0,interProAnnotations:void 0})).actions(e=>({drawRelativeTo(t){e.relativeTo=t},setHideGaps(t){e.hideGaps=t},setAllowedGappyness(t){e.allowedGappyness=t},setLoadingMSA(t){e.loadingMSA=t},setLoadingTree(t){e.loadingTree=t},setWidth(t){e.volatileWidth=t},setHighResScaleFactor(t){e.highResScaleFactor=t},setHeight(t){e.height=t},setError(t){e.error=t},setMousePos(t,r){e.mouseCol=t,e.mouseRow=r},setHighlightedColumns(t){e.highlightedColumns=t},setShowDomains(t){e.showDomains=t},setShowDomainLegend(t){e.showDomainLegend=t},setSubFeatureRows(t){e.subFeatureRows=t},setMouseClickPos(t,r){e.mouseClickCol=t,e.mouseClickRow=r},setRowHeight(t){e.rowHeight=t},setColWidth(t){e.colWidth=t},setScrollY(t){e.scrollY=t},setCurrentAlignment(t){e.currentAlignment=t},toggleCollapsed(t){e.collapsed.includes(t)?e.collapsed.remove(t):e.collapsed.push(t)},setShowOnly(t){e.showOnly=t},setData(t){e.data=(0,J.cast)(t)},setMSAFilehandle(t){e.msaFilehandle=t},setTreeFilehandle(t){e.treeFilehandle=t},setGFFFilehandle(t){e.gffFilehandle=t},setMSA(t){e.data.setMSA(t)},setTree(t){e.data.setTree(t)},setTreeMetadata(t){e.data.setTreeMetadata(t)}})).views(e=>({get hideGapsEffective(){return e.hideGaps&&(e.collapsed.length>0||e.allowedGappyness<100)},get realAllowedGappyness(){return this.hideGapsEffective?e.allowedGappyness:100},get actuallyShowDomains(){return e.showDomains&&!!e.interProAnnotations},get viewInitialized(){return e.volatileWidth!==void 0},get width(){if(e.volatileWidth===void 0)throw new Error("not initialized");return e.volatileWidth}})).views(e=>({extraViewMenuItems(){return[]},get colorScheme(){return ol[e.colorSchemeName]??ol[ff]},get header(){return this.MSA?.getHeader()??{}},get alignmentNames(){return this.MSA?.alignmentNames??[]},get noTree(){return!!this.tree.noTree},get noDomains(){return!e.interProAnnotations},menuItems(){return[]},get treeMetadata(){let t=e.data.treeMetadata;if(!t)return{};try{let r=JSON.parse(t);return typeof r=="object"&&r!==null?r:{}}catch(r){return console.error("failed to parse treeMetadata",r),{}}},get MSA(){let t=e.data.msa;return t?Q0(t,e.currentAlignment,e.msaFormat):null},get numColumns(){return(this.MSA?.getWidth()??0)-this.blanks.length},get tree(){let t=e.data.tree;return t?ma(jj(t)):this.MSA?.getTree()??{noTree:!0,children:[],id:"empty",name:"empty"}},get rowNames(){return this.leaves.map(t=>t.data.name)},get rowNamesSet(){return new Map(this.leaves.map((t,r)=>[t.data.name,r]))},get mouseOverRowName(){let{mouseRow:t}=e;return t===void 0?void 0:this.leaves[t]?.data.name},get hoveredInsertion(){let{mouseCol:t,mouseRow:r}=e;if(t!==void 0&&r!==void 0){let n=this.leaves[r]?.data.name;if(n){let o=this.insertionPositions.get(n)?.find(i=>i.pos===t);if(o)return{rowName:n,col:t,letters:o.letters}}}},get root(){let t=LI(this.tree,r=>r.children);if(bf(t,r=>r.children.length>0?0:1),wf(t,(r,n)=>(r.data.length??1)-(n.data.length??1)),e.showOnly){let r=Us(t,n=>n.data.id===e.showOnly);r&&(t=r)}for(let r of e.collapsed){let n=Us(t,o=>o.data.id===r);n&&(n.children?PI(n):n.parent?.children&&(n.parent.children=n.parent.children.filter(o=>o.data.id!==r)))}return t},get msaAreaWidth(){return e.width-e.treeAreaWidth-e.resizeHandleWidth},get treeAreaWidthMinusMargin(){return e.treeAreaWidth-e.marginLeft},get blanks(){let{hideGapsEffective:t,realAllowedGappyness:r}=e;if(!t)return[];let n=this.leaves.map(l=>this.MSA?.getRow(l.data.name)).filter(rt.notEmpty);if(n.length===0)return[];let o=n.reduce((l,u)=>Math.max(l,u.length),0),i=n.length,s=Math.ceil(r/100*i),a=new Uint32Array(o);for(let l=0;l<i;l++){let u=n[l],d=u.length;for(let A=0;A<o;A++)(A>=d||u.charCodeAt(A)-45>>>0<=1)&&a[A]++}let c=[];for(let l=0;l<o;l++)a[l]>=s&&c.push(l);return c},get blanksSet(){return new Set(this.blanks)},get insertionPositions(){let{blanks:t,rows:r}=this;if(t.length===0||!e.hideGapsEffective)return new Map;let n=new Map;for(let[o,i]of r){let s=QI(t,i);s.length>0&&n.set(o,s)}return n},get rows(){let t=this.MSA;return this.leaves.map(r=>[r.data.name,t?.getRow(r.data.name)]).filter(r=>!!r[1])},get numRows(){return this.leaves.length},get seqPosGlobalColIndex(){return new Map(this.rows.map(([t,r])=>[t,lN(r)]))},get rowMap(){return new Map(this.rows)},get columns(){let t=this.columns2d;return new Map(this.rows.map((r,n)=>[r[0],t[n]]))},get columns2d(){let{hideGapsEffective:t}=e;return this.rows.map(([,r])=>(t?ng(this.blanks,r):r).toUpperCase())},get fontSize(){return Math.min(Math.max(6,e.rowHeight-3),18)},get colStats(){return MD(this.columns2d)},get colStatsSums(){return this.colStats.totals},get sequenceType(){let t=this.colStats.lettersPresent,r=new Set(["A","C","G","T","N"]),n=new Set(["A","C","G","U","N"]),o=t.size>0&&[...t].every(s=>r.has(s)),i=t.size>0&&[...t].every(s=>n.has(s));return o?"dna":i?"rna":"amino"},get colConsensus(){let{colStats:t}=this;return Array.from({length:t.numColumns},(r,n)=>{let o=t.total(n),i=0,s="";t.forEachResidue(n,(c,l)=>{l>i&&(i=l,s=vD(c))});let a=o?i/o:0;return{letter:s,color:a>.4?`hsl(240, 30%, ${100*Math.max(1-a/3,.3)}%)`:void 0}})},get colClustalX(){let{colStats:t}=this;return Array.from({length:t.numColumns},(r,n)=>wD(t,n))},get conservation(){let{colStats:t,sequenceType:r}=this,o=Math.log2(r==="amino"?20:4);return Array.from({length:t.numColumns},(i,s)=>{let a=t.total(s),c=t.gapCount(s),l=a-c,u=0;if(l>0){let d=0;t.forEachResidue(s,(A,f)=>{let g=f/l;d-=g*Math.log2(g)}),u=Math.max(0,1-d/o)*(1-c/a)}return u})},get propertyConservation(){return this.sequenceType==="amino"?oN(this.colStats):[]},get hierarchy(){let t=this.root;FI(t,this.totalHeight,e.treeWidth),t.data.length=0;let r=UI(t),n=r?e.treeWidth/r:0;return HI(t,0,n),Ai(t,o=>{if(o._children){let{min:i,max:s}=OI(o);o.collapsedTipXNear=(o.len??0)+i*n,o.collapsedTipXFar=(o.len??0)+s*n}}),t},get totalHeight(){return di(this.root).length*e.rowHeight},get leaves(){return di(this.hierarchy)},get maxBranchLength(){return GI(this.hierarchy)},get maxDepthToLeaf(){return kc(this.hierarchy)},get allBranchesLength0(){return Ef(this.hierarchy).every(t=>!t.source.data.length)},get showBranchLenEffective(){return this.allBranchesLength0?!1:e.showBranchLen}})).views(e=>({get totalWidth(){return e.numColumns*e.colWidth}})).views(e=>({get dataInitialized(){return(e.data.msa!==""||e.data.tree!=="")&&!e.error},get blocksX(){return by({viewportSize:e.msaAreaWidth,viewportPos:-e.scrollX,blockSize:e.blockSize,mapSize:e.totalWidth})},get blocksY(){return by({viewportSize:e.height,viewportPos:-e.scrollY,blockSize:e.blockSize,mapSize:e.totalHeight})}})).views(e=>({get blocks2d(){return e.blocksY.flatMap(t=>e.blocksX.map(r=>[r,t]))},get isLoading(){return e.loadingMSA||e.loadingTree},get maxScrollX(){return Math.min(-e.totalWidth+(e.msaAreaWidth-100),0)},get maxScrollY(){let t=e.height-e.headerHeight-(e.msaAreaWidth<e.totalWidth?e.minimapHeight:0);return Math.min(-e.totalHeight+t,0)},get showMsaLetters(){return e.drawMsaLetters&&e.rowHeight>=5&&e.colWidth>e.rowHeight/2},get showTreeText(){return e.drawLabels&&e.rowHeight>=5}})).actions(e=>({setDrawMsaLetters(t){e.drawMsaLetters=t},setScrollZoom(t){e.scrollZoom=t},setHoveredTreeNode(t){if(t){let r=Us(e.hierarchy,n=>n.data.id===t);e.hoveredTreeNode=r?{nodeId:t,descendantNames:di(r).map(n=>n.data.name)}:void 0}else e.hoveredTreeNode=void 0},calculateNeighborJoiningTreeFromMSA(){if(e.rows.length<2)throw new Error("Need at least 2 sequences to build a tree");let t=XD(e.rows);e.setTree(t)},resetZoom(){e.setColWidth(12),e.setRowHeight(16)},zoomOutHorizontal(){e.colWidth=Math.max(lf,Math.floor(e.colWidth*.75)),e.scrollX=(0,rt.clamp)(e.scrollX,e.maxScrollX,0)},zoomInHorizontal(){e.colWidth=Math.min(ui,Math.ceil(e.colWidth*1.5)),e.scrollX=(0,rt.clamp)(e.scrollX,e.maxScrollX,0)},zoomInVertical(){e.rowHeight=Math.min(ui,Math.ceil(e.rowHeight*1.5))},zoomOutVertical(){e.rowHeight=Math.max(uf,Math.floor(e.rowHeight*.75))},zoomIn(){(0,_t.transaction)(()=>{this.zoomInHorizontal(),this.zoomInVertical()})},zoomOut(){(0,_t.transaction)(()=>{this.zoomOutHorizontal(),this.zoomOutVertical()})},zoomToPos(t,r,n){(0,_t.transaction)(()=>{let o=(-e.scrollX+r)/e.colWidth,i=(-e.scrollY+n)/e.rowHeight;e.colWidth=(0,rt.clamp)(e.colWidth*t,lf,ui),e.rowHeight=(0,rt.clamp)(e.rowHeight*t,uf,ui),e.scrollX=(0,rt.clamp)(r-o*e.colWidth,e.maxScrollX,0);let s=n-i*e.rowHeight,a=Math.max(0,-e.maxScrollY),c=e.totalHeight-a,l=c>0?(0,rt.clamp)(1-a/c,0,1):1;e.scrollY=(0,rt.clamp)(s*(1-l),e.maxScrollY,0)})},doScrollY(t){e.scrollY=(0,rt.clamp)(e.scrollY+t,e.maxScrollY,0)},setDomains(t){e.interProAnnotations=t,e.setShowDomains(!!t)},applyGFFText(t){let r=wd(t);this.setDomains(Id(r))},doScrollX(t){this.setScrollX(e.scrollX+t)},setScrollX(t){e.scrollX=(0,rt.clamp)(t,e.maxScrollX,0)},toggleTrack(t){e.turnedOffTracks.has(t)?e.turnedOffTracks.delete(t):e.turnedOffTracks.set(t,!0)},setStatus(t){e.status=t}})).views(e=>({get labelWidthMap(){let{rowHeight:t,leaves:r,treeMetadata:n,fontSize:o}=e;return t<=5?new Map:new Map(r.map(i=>{let{name:s}=i.data,a=n[s]?.genome||s;return[s,PD(a,o)]}))},get labelsWidth(){let t=0;for(let r of this.labelWidthMap.values())r>t&&(t=r);return t},get secondaryStructureConsensus(){return e.MSA?.secondaryStructureConsensus},get seqConsensus(){return e.MSA?.seqConsensus},get adapterTrackModels(){let{rowHeight:t,MSA:r,hideGapsEffective:n,blanks:o}=e;return(r?.tracks??[]).filter(s=>!!s.data).map(s=>({model:{...s,data:n?ng(o,s.data):s.data,height:t},ReactComponent:QD}))},get tracks(){let t={model:{id:"conservation",name:"Conservation",height:e.conservationTrackHeight,barColor:"gray"},ReactComponent:vy},r={model:{id:"property-conservation",name:"Property conservation",height:e.conservationTrackHeight,barColor:"#6a51a3"},ReactComponent:vy};return[...this.adapterTrackModels,t,...e.sequenceType==="amino"?[r]:[]]},get turnedOnTracks(){return this.tracks.filter(t=>!e.turnedOffTracks.has(t.model.id))},get showHorizontalScrollbar(){return e.msaAreaWidth<e.totalWidth},visibleColToRowLetter(t,r){let{rowMap:n,blanks:o}=e;return n.get(t)?.[ky(o,r)]},visibleColToSeqPos(t,r){return aN({rowName:t,visibleCol:r,rowMap:e.rowMap,blanks:e.blanks})},visibleColToSeqPosOneBased(t,r){let n=this.visibleColToSeqPos(t,r);return n!==void 0?n+1:void 0},globalColToVisibleCol(t){let{blanks:r,hideGapsEffective:n}=e;return n?sN(r,t):t},seqPosToGlobalCol(t,r){let n=e.rowMap.get(t);return n===void 0?0:e.seqPosGlobalColIndex.get(t)?.[r]??(r===0?0:n.length)},seqPosToVisibleCol(t,r){let n=this.seqPosToGlobalCol(t,r);return this.globalColToVisibleCol(n)}})).views(e=>({get msaAreaHeight(){return e.height-(e.showHorizontalScrollbar?e.minimapHeight:0)-e.headerHeight},get totalTrackAreaHeight(){return(0,rt.sum)(e.turnedOnTracks.map(t=>t.model.height))},get tidyInterProAnnotationTypes(){return new Map(this.tidyInterProAnnotations.map(t=>[t.accession,t]))},get tidyInterProAnnotations(){return e.interProAnnotations?Object.entries(e.interProAnnotations).flatMap(([t,r])=>r.matches.flatMap(({signature:n,locations:o})=>{let{entry:i}=n;return i?o.map(({start:s,end:a,strand:c})=>({id:t,name:i.name,accession:i.accession,description:i.description,featureType:i.featureType,start:s,end:a,strand:c})):[]})).toSorted((t,r)=>og(r)-og(t)):[]},get tidyFilteredInterProAnnotations(){return this.tidyInterProAnnotations.filter(t=>e.featureFilters.get(t.accession))},get tidyFilteredGatheredInterProAnnotations(){return(0,rt.groupBy)(this.tidyFilteredInterProAnnotations,t=>t.id)}})).views(e=>({get showVerticalScrollbar(){return e.msaAreaHeight<e.totalHeight}})).views(e=>({get verticalScrollbarWidth(){return e.showVerticalScrollbar?20:0},get segmentDomainTypes(){return[...e.tidyInterProAnnotationTypes.values()].filter(t=>Wp.has(t.featureType??"")).toSorted((t,r)=>t.start-r.start)},get categoricalDomainTypes(){return[...e.tidyInterProAnnotationTypes.values()].filter(t=>!Wp.has(t.featureType??""))},get fillPalette(){let t=Object.fromEntries(this.segmentDomainTypes.map((n,o)=>[n.accession,Yp[o%Yp.length]])),r=DD(this.categoricalDomainTypes.map(n=>n.accession));return{...t,...r}},get strokePalette(){return Gs(this.fillPalette,([t,r])=>[t,it(r).darken(.1).toHex()])},get segmentLabels(){return new Map(this.segmentDomainTypes.map((t,r)=>{let n=/(\d+)\s*$/.exec(t.name);return[t.accession,n?n[1]:`${r+1}`]}))},get visibleDomainTypes(){return this.categoricalDomainTypes.filter(t=>e.featureFilters.get(t.accession)).toSorted((t,r)=>t.start-r.start)},get domainBands(){let t=new Map;for(let[r,n]of Object.entries(e.tidyFilteredGatheredInterProAnnotations)){let o=n.map((i,s)=>{let a=e.seqPosToVisibleCol(r,i.start-1),c=e.seqPosToVisibleCol(r,i.end-1);return a!==void 0&&c!==void 0?{annotation:i,startCol:a,endCol:c+1,stackIndex:s}:void 0}).filter(rt.notEmpty);o.length>0&&t.set(r,o)}return t},get domainBandsByStart(){return new Map([...this.domainBands].map(([t,r])=>[t,r.toSorted((n,o)=>n.startCol-o.startCol)]))},get mouseOverDomains(){let{mouseCol:t}=e,r=e.mouseOverRowName;return r!==void 0&&t!==void 0?(this.domainBands.get(r)??[]).filter(n=>t>=n.startCol&&t<n.endCol).map(n=>n.annotation):[]},get referenceRowIndex(){let{relativeTo:t}=e;return t===void 0?void 0:e.rowNamesSet.get(t)},get hoveredRowIndices(){let{hoveredTreeNode:t,rowNamesSet:r}=e;return t?t.descendantNames.map(n=>r.get(n)).filter(rt.notEmpty):[]},get highlightedColumnRuns(){let{highlightedColumns:t}=e,r=[];for(let n of[...t??[]].sort((o,i)=>o-i)){let o=r.at(-1);o&&n===o.end+1?o.end=n:r.push({start:n,end:n})}return r},get mouseOverColumnStats(){let{mouseCol:t}=e;if(t===void 0)return;let{colStats:r}=e,n=r.total(t);if(t>=r.numColumns||!n)return;let o=r.gapCount(t),i=r.residueEntries(t).sort((a,c)=>c[1]-a[1]),s=i[0];return{col:t,total:n,gaps:o,gapFraction:o/n,conservation:e.conservation[t]??0,propertyConservation:e.propertyConservation[t],consensusLetter:s?.[0]??"",consensusCount:s?.[1]??0,consensusFraction:s?s[1]/n:0,distribution:i}},getRowData(t){return{data:e.MSA?.getRowData(t),treeMetadata:e.treeMetadata[t]}}})).actions(e=>({setHeaderHeight(t){e.headerHeight=t},setConservationTrackHeight(t){e.conservationTrackHeight=t},reset(){e.setData({tree:"",msa:""}),e.resetZoom(),e.setError(void 0),e.setScrollY(0),e.setScrollX(0),e.setCurrentAlignment(0),e.setTreeFilehandle(void 0),e.setMSAFilehandle(void 0),e.setGFFFilehandle(void 0),e.setDomains(void 0)},async exportSVG(t){let{renderToSvg:r}=await Promise.resolve().then(()=>(Cg(),XI)),n=await r(e,t),o=new Blob([n],{type:"image/svg+xml"});fN(o,"image.svg")},initFilter(t){e.featureFilters.has(t)||e.featureFilters.set(t,!0)},setFilter(t,r){e.featureFilters.set(t,r)},fit(){this.fitVertically(),this.fitHorizontally()},fitVertically(){e.numRows>0&&(e.rowHeight=(0,rt.clamp)(e.msaAreaHeight/e.numRows,uf,ui)),e.scrollY=0},fitHorizontally(){e.numColumns>0&&(e.colWidth=(0,rt.clamp)(e.msaAreaWidth/e.numColumns,lf,ui)),e.scrollX=0},afterCreate(){if(e.highlightColumns?.length&&e.setHighlightedColumns(e.highlightColumns),(0,J.addDisposer)(e,(0,_t.autorun)(()=>{for(let n of e.tidyInterProAnnotationTypes.keys())this.initFilter(n)})),typeof window<"u"&&typeof window.matchMedia=="function"){let n=()=>window.matchMedia(`(resolution: ${window.devicePixelRatio}dppx)`),o=n(),i=()=>{e.setHighResScaleFactor(window.devicePixelRatio),o.removeEventListener("change",i),o=n(),o.addEventListener("change",i)};o.addEventListener("change",i),(0,J.addDisposer)(e,()=>{o.removeEventListener("change",i)})}let t=0;(0,J.addDisposer)(e,(0,_t.autorun)(async()=>{let{treeFilehandle:n}=e;if(n){let o=++t;try{e.setLoadingTree(!0);let i=await il((0,_l.openLocation)(n),s=>{o===t&&e.setStatus(s)});o===t&&(0,_t.transaction)(()=>{e.setTree(i),n.locationType==="BlobLocation"&&e.setTreeFilehandle(void 0)})}catch(i){o===t&&(To(i)?e.setTreeFilehandle(void 0):(console.error(i),e.setError(i)))}finally{o===t&&e.setLoadingTree(!1)}}})),(0,J.addDisposer)(e,(0,_t.autorun)(async()=>{let{treeMetadataFilehandle:n}=e;if(n)try{e.setTreeMetadata(await il((0,_l.openLocation)(n),o=>{e.setStatus(o)}))}catch(o){To(o)||(console.error(o),e.setError(o))}})),(0,J.addDisposer)(e,(0,_t.autorun)(()=>{let n=e.data.gff;if(n)try{e.applyGFFText(n)}catch(o){console.error(o),e.setError(o)}})),(0,J.addDisposer)(e,(0,_t.autorun)(async()=>{let{gffFilehandle:n}=e;if(n)try{let o=await il((0,_l.openLocation)(n),i=>{e.setStatus(i)});e.applyGFFText(o),n.locationType==="BlobLocation"&&e.setGFFFilehandle(void 0)}catch(o){To(o)?e.setGFFFilehandle(void 0):(console.error(o),e.setError(o))}}));let r=0;(0,J.addDisposer)(e,(0,_t.autorun)(async()=>{let{msaFilehandle:n}=e;if(n){let o=++r;try{e.setLoadingMSA(!0),e.setError(void 0);let i=await il((0,_l.openLocation)(n),s=>{o===r&&e.setStatus(s)});o===r&&(0,_t.transaction)(()=>{e.setMSA(i),n.locationType==="BlobLocation"&&e.setMSAFilehandle(void 0)})}catch(i){o===r&&(To(i)?e.setMSAFilehandle(void 0):(console.error(i),e.setError(i)))}finally{o===r&&e.setLoadingMSA(!1)}}})),(0,J.addDisposer)(e,(0,_t.autorun)(()=>{e.colorSchemeName.includes("dynamic")&&e.colStats,e.showColumnStats&&(e.colStats,e.conservation,e.propertyConservation),e.columns})),(0,J.addDisposer)(e,(0,_t.autorun)(()=>{e.autoTreeAreaWidth&&(e.noTree||!e.drawTree)&&e.labelsWidth&&e.setTreeAreaWidth(e.labelsWidth+e.marginLeft+12)})),(0,J.addDisposer)(e,(0,_t.autorun)(()=>{e.setTreeWidth(Math.max(50,e.treeAreaWidth-e.labelsWidth-10-e.marginLeft))}))}})).postProcessSnapshot(({data:e,...t})=>({...t,data:{...t.treeFilehandle?{}:{tree:e.tree},...t.msaFilehandle?{}:{msa:e.msa},...t.treeMetadataFilehandle?{}:{treeMetadata:e.treeMetadata},...t.gffFilehandle?{}:{gff:e.gff}}}))}var rt,_l,Ui,J,_t,hA,Dy=m(()=>{rt=p(be(),1),_l=p(Ey(),1),Ui=p(hD(),1),J=p(zt(),1);Mc();_t=p(Ls(),1);Sd();yD();ID();m0();Iy();RD();_D();Bc();ND();Ed();FD();Ag();OD();UD();jD();WD();qD();ZD();tN();iN();cN();uN();pA();ho();dN();hA=$j});var Ny,pN,Wj,Dpe,gN=m(()=>{Ny=p(Q(),1),pN=p(mD(),1),Wj=p(Sg(),1);Dy();Cy();Dpe=(0,pN.createJBrowseTheme)()});var Ly=m(()=>{Cg();Cy();gN();Dy()});function Xj(e){try{return new URL(e).host}catch{return e}}async function IN(e,t){let r;try{r=await fetch(e,t)}catch(n){throw n instanceof TypeError?new Error(`Could not reach ${Xj(e)} \u2014 the request failed at the network level. This is usually a CORS restriction (the server refused to let this site read the response), an offline connection, or a blocked request.`,{cause:n}):n}if(!r.ok)throw new Error(`HTTP ${r.status} fetching ${e} ${await r.text()}`);return r}async function qr(e,t){return(await IN(e,t)).text()}async function Qa(e,t){return(await IN(e,t)).json()}function SN(e){return new Promise(t=>setTimeout(t,e))}var ji=m(()=>{"use strict"});async function vN({check:e,intervalSeconds:t,onCountdown:r}){for(;;){if(await e())return;for(let n=t;n>0;n--)r(n),await SN(1e3)}}var BN=m(()=>{"use strict";ji()});function Oy(e,t){try{let r=globalThis.localStorage.getItem(e);return r===null?t:JSON.parse(r)}catch(r){return console.error(r),t}}function MN(e,t){let[r,n]=(0,TN.useState)(()=>Oy(e,t));return[r,i=>{n(i);try{globalThis.localStorage.setItem(e,JSON.stringify(i))}catch(s){console.error(s)}}]}var TN,Gy=m(()=>{"use strict";TN=p(Q())});function Zj(){return Oy(Hy,_a).trim()||_a}async function EA({tool:e,params:t}){return(await qr(`${Uy}/${e}/run`,{method:"POST",body:new URLSearchParams({email:Zj(),...t})})).trim()}async function bA({tool:e,jobId:t,intervalSeconds:r=10,onCountdown:n}){let o=0;await vN({intervalSeconds:r,onCountdown:n,check:async()=>{let i;try{i=(await qr(`${Uy}/${e}/status/${t}`)).trim()}catch(s){if(o+=1,o>=t7)throw new Error(`Could not reach EBI to check ${e} job ${t} after ${o} tries`,{cause:s});return console.warn(`[msaview] EBI status check ${o} failed, retrying:`,s),!1}if(o=0,i==="FINISHED")return!0;if(e7.has(i))throw new Error(`EBI ${e} job ${t} returned status ${i}`);return!1}})}async function kl({tool:e,jobId:t,type:r}){return qr(`${Uy}/${e}/result/${t}/${r}`)}var Uy,Hy,_a,e7,t7,Dl=m(()=>{"use strict";ji();BN();Gy();Uy="https://www.ebi.ac.uk/Tools/services/rest",Hy="msa-ebiContactEmail",_a="colin.diesh@gmail.com";e7=new Set(["ERROR","FAILURE","NOT_FOUND"]);t7=5});function r7(e){return(e.hits??[]).map(t=>{let r=Number.parseInt(t.hit_uni_ox??"",10);return{description:[{accession:t.hit_acc??"unknown",id:t.hit_id??t.hit_acc??"unknown",sciname:t.hit_uni_os??t.hit_os??"unknown",taxid:Number.isNaN(r)?void 0:r,title:t.hit_uni_de??t.hit_desc}],hsps:(t.hit_hsps??[]).flatMap(n=>n.hsp_hseq?[{hseq:n.hsp_hseq}]:[])}})}function RN(e){return`https://www.ebi.ac.uk/jdispatcher/sss/${wA}/summary?jobId=${e}`}async function n7({jobId:e,onProgress:t}){t(`Checking BLAST status for job: ${e}...`),await bA({tool:wA,jobId:e,onCountdown:n=>{t(`Re-checking BLAST status in... ${n}`)}});let r=r7(JSON.parse(await kl({tool:wA,jobId:e,type:"json"})));if(r.length===0)throw new Error("No hits found");return{rid:e,hits:r}}async function QN({query:e,blastDatabase:t,onProgress:r,onRid:n}){r("Submitting to EBI BLAST...");let o=await EA({tool:wA,params:{program:"blastp",stype:"protein",database:t,sequence:e}});return n(o),n7({jobId:o,onProgress:r})}var wA,Vy=m(()=>{"use strict";Dl();wA="ncbiblast"});var RL=X((hhe,ML)=>{ML.exports=JBrowseExports["@jbrowse/core/data_adapters/BaseAdapter"]});var kL={};Bt(kL,{default:()=>RA});var QL,_L,RA,DL=m(()=>{"use strict";QL=p(ss()),_L=p(RL());yT();RA=class extends _L.BaseAdapter{async configurePre(){let t=this.getSubAdapter;if(t)return(await t({...(0,QL.readConfObject)(this.config),type:"BgzipFastaAdapter"})).dataAdapter;throw new Error("no get subadapter")}configure(){return this.configureP??=this.configurePre().catch(t=>{throw this.configureP=void 0,t}),this.configureP}async getMSARefs(){return this.refNamesP??=this.configure().then(t=>t.getRefNames()).catch(t=>{throw this.refNamesP=void 0,t}),this.refNamesP}getMsaRegex(){return new RegExp(this.getConf("msaRegex"))}refNameToMsaId(t){return t.split(this.getMsaRegex())[0]}async getMSAList(){let t=await this.getMSARefs();return[...new Set(t.map(n=>this.refNameToMsaId(n)))]}async getMSA(t){let r=await this.configure(),o=(await this.getMSARefs()).filter(i=>this.refNameToMsaId(i)===t);return Gh(r.getFeaturesInMultipleRegions(o.map(i=>({refName:i,start:0,end:1e9,assemblyName:""}))).pipe(Uh()))}}});var $L=X(jL=>{"use strict";var Fa=Q();function _7(e,t){return e===t&&(e!==0||1/e===1/t)||e!==e&&t!==t}var k7=typeof Object.is=="function"?Object.is:_7,D7=Fa.useState,N7=Fa.useEffect,L7=Fa.useLayoutEffect,F7=Fa.useDebugValue;function P7(e,t){var r=t(),n=D7({inst:{value:r,getSnapshot:t}}),o=n[0].inst,i=n[1];return L7(function(){o.value=r,o.getSnapshot=t,tx(o)&&i({inst:o})},[e,r,t]),N7(function(){return tx(o)&&i({inst:o}),e(function(){tx(o)&&i({inst:o})})},[e]),F7(r),r}function tx(e){var t=e.getSnapshot;e=e.value;try{var r=t();return!k7(e,r)}catch{return!0}}function O7(e,t){return t()}var G7=typeof window>"u"||typeof window.document>"u"||typeof window.document.createElement>"u"?O7:P7;jL.useSyncExternalStore=Fa.useSyncExternalStore!==void 0?Fa.useSyncExternalStore:G7});var YL=X((Mhe,WL)=>{"use strict";WL.exports=$L()});var PF,OF,GF=m(()=>{"use client";we();PF=p(O(),1),OF=W((0,PF.jsx)("path",{d:"M19 19H5V5h7V3H5c-1.11 0-2 .9-2 2v14c0 1.1.89 2 2 2h14c1.1 0 2-.9 2-2v-7h-2zM14 3v2h3.59l-9.83 9.83 1.41 1.41L19 6.41V10h2V3z"}),"OpenInNew")});function Vl(e){let{children:t,...r}=e;return wx.default.createElement(UF.Link,{...r,target:"_blank",rel:"noreferrer"},t," ",wx.default.createElement(OF,{fontSize:"small"}))}var wx,UF,Ix=m(()=>{"use strict";wx=p(Q());GF();UF=p(U())});var wP=X((yxe,bP)=>{bP.exports=JBrowseExports["@jbrowse/core/pluggableElementTypes/ViewType"]});var $l,IP,KA,SP=m(()=>{"use strict";$l=p(Q()),IP=p(Xe()),KA=class extends $l.Component{constructor(t){super(t),this.state={hasError:!1,error:null}}static getDerivedStateFromError(t){return{hasError:!0,error:t}}componentDidCatch(t,r){console.error("MsaViewPanel error:",t,r.componentStack)}render(){return this.state.hasError?$l.default.createElement("div",{style:{padding:20}},$l.default.createElement(IP.ErrorMessage,{error:this.state.error})):this.props.children}}});function U$({jobId:e}){return Nx.default.createElement(vP.Typography,null,"Job ",e," (",Nx.default.createElement(Vl,{href:RN(e)},"see status"),")")}var Nx,vP,Lx,BP=m(()=>{"use strict";Nx=p(Q()),vP=p(U());Ix();Vy();Lx=U$});var kn,XA,Fx,TP,MP,H$,V$,RP,QP=m(()=>{"use strict";kn=p(Q()),XA=p(Xe()),Fx=p(U()),TP=p(Y()),MP=p(Ut());BP();H$=(0,MP.makeStyles)()(e=>({margin:{padding:20},loading:{background:e.palette.background.paper}})),V$=(0,TP.observer)(function({model:t}){let{progress:r,rid:n,error:o}=t,{classes:i}=H$();return kn.default.createElement("div",{className:i.margin},kn.default.createElement(XA.LoadingEllipses,{message:"Running EBI BLAST",variant:"h5"}),o?kn.default.createElement("div",null,n?kn.default.createElement(Lx,{jobId:n}):null,kn.default.createElement(XA.ErrorMessage,{error:o})):n?kn.default.createElement("div",{className:i.loading},kn.default.createElement(Lx,{jobId:n}),kn.default.createElement(Fx.Typography,null,r)):kn.default.createElement(Fx.Typography,null,r||"Initializing BLAST query"))}),RP=V$});var NP={};Bt(NP,{default:()=>W$});var zi,_P,kP,DP,j$,$$,W$,LP=m(()=>{"use strict";zi=p(Q()),_P=p(Xe()),kP=p(Y());Ly();DP=p(Ut());SP();QP();j$=(0,DP.makeStyles)()({loadingContainer:{padding:20}}),$$=(0,kP.observer)(function({model:t}){let{classes:r}=j$(),{blastParams:n,loadingStoredData:o}=t;return zi.default.createElement(KA,null,zi.default.createElement("div",null,n?zi.default.createElement(RP,{model:t}):o?zi.default.createElement("div",{className:r.loadingContainer},zi.default.createElement(_P.LoadingEllipses,{message:"Loading MSA data",variant:"h6"})):zi.default.createElement(fA,{model:t})))}),W$=$$});var q$={};Bt(q$,{default:()=>ZA});var GP=p(iC()),Ox=p(ss()),UP=p(be()),Gx=p(zt());we();var Yw=p(O(),1),qw=W((0,Yw.jsx)("path",{d:"M20 2H4c-1.1 0-2 .9-2 2v16c0 1.1.9 2 2 2h16c1.1 0 2-.9 2-2V4c0-1.1-.9-2-2-2M8 20H4v-4h4zm0-6H4v-4h4zm0-6H4V4h4zm6 12h-4v-4h4zm0-6h-4v-4h4zm0-6h-4V4h4zm6 12h-4v-4h4zm0-6h-4v-4h4zm0-6h-4V4h4z"}),"GridOn");var vL=p(Q()),BL=p(be());var Pl=p(Q()),IL=p(Y());var qy=p(Q()),CL=p(be()),zy=p(Y());var Xw=p(Ut());function ci(e){return!!e&&typeof e=="object"&&"hoverPosition"in e&&!!e.hoverPosition}function Kw(e){return/AF-([A-Z0-9]+)-F\d+/.exec(e)?.[1]}var af=(0,Xw.makeStyles)()({highlight:{height:"100%",background:"rgba(255,255,0,0.2)",border:"1px solid rgba(50,50,0,0.2)",position:"absolute",zIndex:99,textAlign:"center",pointerEvents:"none",overflow:"hidden"}});var yL=p(jp()),xL=p(be()),mt=p(zt());function eI(e){let t=e.strand,r=e.refName;if(t!==-1&&t!==1)throw new Error(`Invalid strand value: ${t}. Expected 1 or -1.`);if(!r)throw new Error("refName is required");let n=new Map;for(let c of e.subfeatures??[])if(c.type==="CDS"&&c.start<c.end){let l=`${c.start}-${c.end}`;n.has(l)||n.set(l,c)}let o=[...n.values()].sort((c,l)=>t*(c.start-l.start)),i={},s={},a={};if(o.length!==0){let l=(3-(o[0]?.phase??0))%3,u=-1;for(let d of o){let A=d.end-d.start;for(let f=0;f<A;f++){let g=t===1?d.start+f:d.end-1-f,h=Math.floor(l++/3);i[g]=h,h!==u?(s[h]=g,a[h]=[g],u=h):a[h].push(g)}}}return{g2p:i,p2g:s,p2gCodon:a,refName:r,strand:t}}function tI(e,t){let r=e[t];if(r===void 0)return;let n=[...r].sort((i,s)=>i-s),o=[];for(let i of n){let s=o.at(-1);s?.[1]===i?s[1]=i+1:o.push([i,i+1])}return o}var MA=p(Ls());Ly();var aL=p(be());function hN(e,t){let r=e.sciname.replaceAll(" ","_");if(e.taxid&&t?.has(e.taxid)){let n=t.get(e.taxid);n.commonName&&(r=n.commonName.split(" ").map(o=>o.charAt(0).toUpperCase()+o.slice(1).toLowerCase()).join("_"))}return`${e.accession}-${r}`}function yN(e){return e.replaceAll("-","")}var xA=p(be());function Rr(e){return(0,xA.getContainingView)(e)}function xN(e){return[...new Set(e.filter(t=>!!t))]}function CN(e,t){return t.filter(r=>!!r).join(e)}function Yj(e){let r=(e.get("subfeatures")??[]).filter(n=>(n.get("type")==="mRNA"||n.get("type")==="transcript")&&n.get("subfeatures")?.some(o=>o.get("type")==="CDS"));return r.length>0?r:[e]}function yA(e){let t=(0,xA.sum)(e.get("subfeatures")?.filter(r=>r.get("type")==="CDS").map(r=>r.get("end")-r.get("start"))??[]);return{len:Math.floor(t/3),mod:t%3}}function Hi(e){return e?.id()??""}function qj(e){return e?xN([e.id(),e.get("name"),e.get("id"),e.get("transcript_id")]):[]}function Ba(e,t){return qj(e).includes(t)}function Ta(e){return e?CN(" ",[e.get("name"),e.get("id")]):""}function no(e){return e?CN(" ",[e.get("gene_name")??e.get("name"),e.get("id")?`(${e.get("id")})`:void 0]):""}function EN(e,t){return`BLAST - ${no(e)} - ${Ta(t)}`}function CA(e){return Yj(e).toSorted((r,n)=>yA(n).len-yA(r).len)}function Ma(e){return e.replaceAll("*","").replaceAll("&","")}function Ra(e){return xN([e.id(),e.get("id"),e.get("name"),e.get("gene_id"),e.get("gene_name")])}Jh();function Ho(e,t,r){let n;return()=>(n??=zh(e,t,{upgrade:r}).catch(o=>{throw n=void 0,o}),n)}var zj="jbrowse-msaview-blast-cache",Vi="blast-results",Jj=2,Fy=Ho(zj,Jj,(e,t)=>{t<2&&e.objectStoreNames.contains(Vi)&&e.deleteObjectStore(Vi),e.objectStoreNames.contains(Vi)||e.createObjectStore(Vi,{keyPath:"id"})});function Kj(e,t,r,n){let o=n?`:${n}`:"";return`${t}:${r}${o}:${e}`}async function bN({proteinSequence:e,blastDatabase:t,msaAlgorithm:r,msa:n,tree:o,treeMetadata:i,rid:s,geneId:a,transcriptId:c,transcriptName:l,geneName:u}){let d=await Fy(),f={id:Kj(e,t,r,c),proteinSequence:e,blastDatabase:t,msaAlgorithm:r,msa:n,tree:o,treeMetadata:i,rid:s,timestamp:Date.now(),geneId:a,transcriptId:c,transcriptName:l,geneName:u};return await d.put(Vi,f),f}async function wN(){return(await(await Fy()).getAll(Vi)).toSorted((r,n)=>n.timestamp-r.timestamp)}async function Py(e){await(await Fy()).delete(Vi,e)}Vy();Dl();var o7={clustalo:{params:{},msaResult:"aln-clustal_num",treeResult:"phylotree"},muscle:{params:{format:"clw",tree:"tree1"},msaResult:"fa",treeResult:"phylotree"},kalign:{params:{stype:"protein"},msaResult:"fa",treeResult:"phylotree"},mafft:{params:{stype:"protein"},msaResult:"fa",treeResult:"phylotree"}};async function IA({algorithm:e,sequence:t,onProgress:r}){let n=o7[e];r(`Launching ${e} MSA...`);let o=await EA({tool:e,params:{...n.params,sequence:t}});return await bA({tool:e,jobId:o,onCountdown:i=>{r(`Re-checking MSA status in... ${i}`)}}),{msa:await kl({tool:e,jobId:o,type:n.msaResult}),tree:await kl({tool:e,jobId:o,type:n.treeResult})}}var ka="jbrowse-plugin-msaview",Da="colin.diesh@gmail.com",_N="https://eutils.ncbi.nlm.nih.gov/entrez/eutils";function SA(e){let t=new URLSearchParams({...e,tool:ka,email:Da});return`${_N}/efetch.fcgi?${t.toString()}`}function kN(e){return[`${_N}/efetch.fcgi`,{method:"POST",body:new URLSearchParams({...e,tool:ka,email:Da})}]}ji();var i7="jbrowse-msaview-taxonomy-cache",Nl="common-names",s7=2,DN=Ho(i7,s7,e=>{e.objectStoreNames.contains(Nl)&&e.deleteObjectStore(Nl),e.createObjectStore(Nl,{keyPath:"taxid"})});async function a7(e){let r=(await DN()).transaction(Nl,"readonly"),n=await Promise.all(e.map(o=>r.store.get(o)));return await r.done,n}async function c7(e){let r=(await DN()).transaction(Nl,"readwrite");for(let n of e)await r.store.put(n);await r.done}async function Na(e){let t=new Map,r=[],n=await a7(e);for(let s=0;s<e.length;s++){let a=e[s],c=n[s];c?t.set(a,{sciname:c.sciname,commonName:c.commonName}):r.push(a)}if(r.length===0)return t;let o=100,i=[];for(let s=0;s<r.length;s+=o){let a=r.slice(s,s+o),c=a.join(",");try{let l=await qr(SA({db:"taxonomy",id:c,retmode:"xml"})),u=new Map,d=/<Taxon>\s*<TaxId>(\d+)<\/TaxId>/g,A;for(;(A=d.exec(l))!==null;){let f=Number(A[1]),g=A.index,h=1,x=g+A[0].length;for(;h>0&&x<l.length;){let I=l.indexOf("<Taxon>",x),S=l.indexOf("</Taxon>",x);if(S===-1)break;I!==-1&&I<S?(h++,x=I+7):(h--,x=S+8)}let w=l.slice(g,x),y=u.get(f),v=w.includes("<LineageEx>"),b=y?.includes("<LineageEx>");(!y||v&&!b)&&u.set(f,w)}for(let f of a){let g=u.get(f);if(g){let h=/<GenbankCommonName>(.*?)<\/GenbankCommonName>/.exec(g),x=/<CommonName>(.*?)<\/CommonName>/.exec(g),w=/<ScientificName>(.*?)<\/ScientificName>/.exec(g),y=h?.[1]??x?.[1],v=w?.[1]??"";t.set(f,{sciname:v,commonName:y}),i.push({taxid:f,sciname:v,commonName:y})}}}catch(l){console.error("Failed to fetch taxonomy data:",l)}}return i.length>0&&await c7(i),t}async function NN({self:e}){let{blastDatabase:t,msaAlgorithm:r,proteinSequence:n,selectedTranscript:o}=e.blastParams,i=Ma(n),s=h=>{e.setProgress(h)},{hits:a,rid:c}=await QN({query:i,blastDatabase:t,onProgress:s,onRid:h=>{e.setRid(h)}});e.setProgress("Fetching species taxonomy info...");let l=a.map(h=>h.description[0]?.taxid).filter(h=>h!==void 0),u=await Na(l),d={},A=a.map(h=>{let x=h.description[0]??{accession:"unknown",id:"unknown",sciname:"unknown"},w=hN(x,u),y=yN(h.hsps[0]?.hseq??"");return d[w]=l7(x,u),`>${w}
+${y}`}),f=await IA({algorithm:r,sequence:[`>QUERY
+${i}`,...A].join(`
+`),onProgress:s}),g=JSON.stringify(d);return await bN({proteinSequence:i,blastDatabase:t,msaAlgorithm:r,msa:f.msa,tree:f.tree,treeMetadata:g,rid:c,geneId:o?.get("parentId"),transcriptId:o?.id(),transcriptName:o?.get("name")??o?.get("id"),geneName:o?.get("gene_name")??o?.get("parentId")}),{...f,treeMetadata:g}}function l7(e,t){let r={},n=e.taxid?t.get(e.taxid):void 0;return n?.sciname&&(r["Scientific name"]=n.sciname),n?.commonName&&(r["Common name"]=n.commonName),e.accession&&(r.Accession=e.accession),e.id&&(r.ID=e.id),e.title&&(r.Description=e.title),r}ji();var FN="https://api.ncbi.nlm.nih.gov/datasets/v2",PN="https://eutils.ncbi.nlm.nih.gov/entrez/eutils",jy=100;function vA(e){let t=e.includes("?")?"&":"?";return`${e}${t}tool=${ka}&email=${encodeURIComponent(Da)}`}async function ON(e,t){for(let r of e){let n=r.trim();if(!n)continue;if(/^\d+$/.test(n))return{geneId:n,matched:n};let o=n.replace(/^\w+:/,"").replace(/\.\d+$/,""),i=`${o}[Gene Name] AND ${t}[taxid]`,a=(await Qa(vA(`${PN}/esearch.fcgi?db=gene&term=${encodeURIComponent(i)}&retmode=json&retmax=1`))).esearchresult?.idlist?.[0];if(a)return{geneId:a,matched:o}}}async function u7(e,{taxa:t,exclude:r,limit:n=jy}={}){let o=await Qa(vA(`${FN}/gene/id/${e}/orthologs?returned_content=COMPLETE`)),i=new Map;for(let{gene:s}of o.reports??[]){let a=Number(s?.tax_id);if(s?.gene_id&&a!==r&&(t?.has(a)??!0)&&!i.has(a)&&i.set(a,{taxId:a,geneId:s.gene_id,scientificName:s.taxname??String(a),commonName:s.common_name}),i.size>=n)break}return[...i.values()]}var LN=150;async function GN(e){let t=new Map;for(let r=0;r<e.length;r+=LN){let n=e.slice(r,r+LN),o=await Qa(vA(`${FN}/gene/id/${n.join(",")}/product_report?page_size=${n.length}`));for(let{product:i}of o.reports??[]){let s=(i?.transcripts??[]).map(c=>({acc:c.protein?.accession_version,len:c.protein?.length??0,mane:/select/i.test(c.select_category??"")})).filter(c=>!!c.acc),a=s.find(c=>c.mane)??[...s].sort((c,l)=>l.len-c.len).at(0);i?.gene_id&&a&&t.set(i.gene_id,a.acc)}}return t}function UN(e){let t=new Map,r,n=[];for(let o of e.split(`
+`))o.startsWith(">")?(r&&t.set(r,n.join("")),r=o.slice(1).split(/\s+/)[0],n=[]):n.push(o.trim());return r&&t.set(r,n.join("")),t}function f7(e){return e.replace(/[^A-Za-z0-9]+/g,"_").replace(/^_+|_+$/g,"")}function $y(e){let t=new Map;return e.map(r=>{let n=f7(r)||"row",o=t.get(n)??0;return t.set(n,o+1),o===0?n:`${n}_${o+1}`})}async function HN(e){let t=(await GN([e])).get(e);if(!t)return;let r=UN(await qr(vA(`${PN}/efetch.fcgi?db=protein&id=${t}&rettype=fasta&retmode=text`))).get(t);return r?{accession:t,sequence:r}:void 0}async function VN({geneId:e,taxa:t,exclude:r,limit:n,onProgress:o}){o("Finding orthologs across species...");let i=await u7(e,{taxa:t,exclude:r,limit:n});if(i.length<2)throw new Error(`Only ${i.length} ortholog(s) found for this gene \u2014 not enough to align`);o("Selecting a representative protein per species...");let s=await GN(i.map(A=>A.geneId)),a=i.filter(A=>s.has(A.geneId));if(a.length<2)throw new Error("Could not resolve representative proteins for the orthologs");o(`Fetching ${a.length} protein sequences...`);let c=a.map(A=>s.get(A.geneId)),l=UN(await qr(...kN({db:"protein",id:c.join(","),rettype:"fasta",retmode:"text"}))),u=$y(a.map(A=>A.commonName??A.scientificName)),d=a.map((A,f)=>{let g=s.get(A.geneId);return{taxId:A.taxId,label:u[f],scientificName:A.scientificName,commonName:A.commonName,geneId:A.geneId,protein:g,sequence:l.get(g)??""}}).filter(A=>A.sequence);if(d.length<2)throw new Error("Could not fetch protein sequences for the orthologs");return d}async function jN({self:e}){let{taxId:t,taxa:r,maxSpecies:n,geneCandidates:o,msaAlgorithm:i,proteinSequence:s}=e.orthologParams,a=h=>{e.setProgress(h)};a("Resolving gene at NCBI...");let c=await ON(o,t);if(!c)throw new Error(`Could not resolve any of ${o.join(", ")} to an NCBI gene in taxon ${t}. Try the NCBI BLAST tab, which needs no gene identifier.`);let l=await A7(c.geneId),u=s?Ma(s):l?.sequence;if(!u)throw new Error(`No query protein: none was supplied and NCBI returned no representative protein for gene ${c.geneId}.`);let d=await VN({geneId:c.geneId,taxa:r?new Set(r):void 0,exclude:t,limit:n,onProgress:a}),A=await d7(t,d);e.setQuerySeqName(A);let f={[A]:m7(e,c.geneId,u,l)};for(let h of d)f[h.label]=p7(h);return{...await IA({algorithm:i,sequence:[`>${A}
+${u}`,...d.map(h=>`>${h.label}
 ${h.sequence}`)].join(`
-`),onProgress:s}),treeMetadata:JSON.stringify(f)}}async function Gj(e){try{return await wN(e)}catch(t){console.warn("[msaview-orthologs] query protein lookup failed:",t);return}}function Uj(e,t,r,n){let o=e.orthologParams?.selectedTranscript,i={"Gene ID":t},s=o?.get("name")??o?.get("id");return s&&(i.Transcript=s),n?.sequence===r&&(i.Accession=n.accession),i}function Hj(e){let t={"Scientific name":e.scientificName,Accession:e.protein,"Gene ID":e.geneId};return e.commonName&&(t["Common name"]=e.commonName),t}fh();var BN=p(Ay());async function TN({location:e,name:t}){let r=i=>(0,BN.openLocation)({uri:i,locationType:"UriLocation"}),n=await r(`${e.uri}.idx`).readFile("utf8"),o=Vj(n,t);if(o){let s=await new oa({filehandle:r(e.uri),gziFilehandle:r(`${e.uri}.gzi`)}).read(o.length,o.offset);return new TextDecoder().decode(s).trim()}}var vN=e=>e.replace(/\.\d+$/,"");function Vj(e,t){let r=vN(t);for(let n of e.split(`
-`)){let[o,i,s]=n.split("	");if(o&&vN(o)===r)return{offset:Number(i),length:Number(s)}}}var MN=p(we());function RN({model:e}){let{hovered:t}=(0,MN.getSession)(e),{querySeqName:r,transcriptToMsaMap:n,connectedView:o,mafRegion:i}=e;if(!o?.initialized||!ui(t))return;let{coord:s,refName:a}=t.hoverPosition,c=s-1;if(i)return a!==i.refName||!o.assemblyNames.includes(i.assemblyName)||c<i.start||c>=i.end?void 0:e.seqPosToVisibleCol(r,c-i.start);if(a===n?.refName){let l=n.g2p[c];if(l!==void 0)return e.seqPosToVisibleCol(r,l)}}var jj="jbrowse-msaview-domain-cache",gA="domains",$j=1,QN=$o(jj,$j,e=>{e.objectStoreNames.contains(gA)||e.createObjectStore(gA,{keyPath:"accession"})});async function _N(e){let r=(await QN()).transaction(gA,"readonly"),n=await Promise.all(e.map(o=>r.store.get(o)));return await r.done,n}async function kN(e){let r=(await QN()).transaction(gA,"readwrite");for(let n of e)await r.store.put(n);await r.done}function Wo(e,t){return new RegExp(`<${t}>(.*?)</${t}>`,"s").exec(e)?.[1]}function Wj(e){let t={},r=/<GBQualifier>([\s\S]*?)<\/GBQualifier>/g,n;for(;(n=r.exec(e))!==null;){let o=Wo(n[1],"GBQualifier_name"),i=Wo(n[1],"GBQualifier_value");o&&i!==void 0&&t[o]===void 0&&(t[o]=i)}return t}function Yj(e){let t=[],r=[],n=/<GBInterval>([\s\S]*?)<\/GBInterval>/g,o;for(;(o=n.exec(e))!==null;){let i=o[1],s=Wo(i,"GBInterval_from"),a=Wo(i,"GBInterval_to"),c=Wo(i,"GBInterval_point");s&&a?(t.push(Number(s)),r.push(Number(a))):c&&(t.push(Number(c)),r.push(Number(c)))}return t.length>0?{start:Math.min(...t),end:Math.max(...r)}:void 0}var qj=2;function zj(e){let t=Wo(e,"GBFeature_key"),r=Wj(e),n=r.db_xref,o=Yj(e);if((t==="Region"||t==="Site")&&n?.startsWith("CDD:")&&o&&o.end-o.start+1>=qj){let i=n.replace("CDD:",""),s=t==="Region",a=r.note?.split(/[[(]/)[0]?.trim(),c=s?r.region_name??i:a||r.site_type||"site",l=s?i:`${i}:${c}`;return{signature:{entry:{name:c,description:r.note??c,accession:l}},locations:[o]}}}function Jj(e){let t=new Map,r=/<GBSeq>([\s\S]*?)<\/GBSeq>/g,n;for(;(n=r.exec(e))!==null;){let o=n[1],i=[],s=/<GBFeature>([\s\S]*?)<\/GBFeature>/g,a;for(;(a=s.exec(o))!==null;){let c=zj(a[1]);c&&i.push(c)}for(let c of[Wo(o,"GBSeq_accession-version"),Wo(o,"GBSeq_primary-accession")])c&&t.set(c,i)}return t}async function DN(e){let t=[...new Set(e)].filter(Boolean),r=new Map,n=await _N(t),o=[];t.forEach((a,c)=>{let l=n[c];l?r.set(a,l.matches):o.push(a)});let i=[],s=100;for(let a=0;a<o.length;a+=s){let c=o.slice(a,a+s),l=await zt(pA({db:"protein",id:c.join(","),rettype:"gp",retmode:"xml"})),u=Jj(l);for(let d of c){let A=u.get(d);A!==void 0&&(r.set(d,A),i.push({accession:d,matches:A}))}}return i.length>0&&await kN(i),r}async function NN(e){let t=e.data.treeMetadata;if(!t)throw new Error("No sequence metadata available to look up domains");let r=JSON.parse(t),n=Object.entries(r).map(([s,a])=>({rowName:s,accession:a.Accession})).filter(s=>!!s.accession);if(n.length===0)throw new Error("No NCBI accessions found in alignment rows");e.setProgress(`Fetching protein domains from NCBI for ${n.length} sequences...`);let o=await DN(n.map(s=>s.accession)),i={};for(let{rowName:s,accession:a}of n){let c=o.get(a);c&&c.length>0&&(i[s]={matches:c,xref:[{id:s}]})}if(Object.keys(i).length===0)throw new Error("No CDD domain annotations found for these proteins");e.setDomains(i)}var Kj="jbrowse-msaview-data",Xj=1,Ql="msa-data",Ny=$o(Kj,Xj,e=>{e.objectStoreNames.contains(Ql)||e.createObjectStore(Ql,{keyPath:"id"}).createIndex("timestamp","timestamp",{unique:!1})});function LN(){return`msa-${Date.now()}-${Math.random().toString(36).slice(2,11)}`}async function PN(e,t){try{let r=await Ny(),n={id:e,msa:t.msa,tree:t.tree,treeMetadata:t.treeMetadata,timestamp:Date.now()};return await r.put(Ql,n),!0}catch(r){return console.warn("Failed to store MSA data:",r),!1}}async function FN(e){try{let r=await(await Ny()).get(Ql,e);return r?{msa:r.msa,tree:r.tree,treeMetadata:r.treeMetadata}:void 0}catch(t){console.warn("Failed to retrieve MSA data:",t);return}}async function ON(e=10080*60*1e3){try{let t=await Ny(),r=Date.now()-e,i=await t.transaction(Ql,"readwrite").store.index("timestamp").openCursor(IDBKeyRange.upperBound(r)),s=0;for(;i;)await i.delete(),s++,i=await i.continue();return s}catch(t){return console.warn("Failed to cleanup old MSA data:",t),0}}function Zj(e){let t=e;return t.type==="ProteinView"&&Array.isArray(t.structures)}function GN(e){return e.filter(Zj)}function UN(e,t){if(t<0||t>=e.length)return;let r=0;for(let n=0;n<t;n++)e[n]!=="-"&&r++;if(e[t]!=="-")return r}function VN(e){let{dataStoreId:t,rows:r}=e;t&&r.length===0&&(async()=>{try{e.setLoadingStoredData(!0);let n=await FN(t);n&&(n.msa&&e.setMSA(n.msa),n.tree&&e.setTree(n.tree),n.treeMetadata&&e.setTreeMetadata(n.treeMetadata))}catch(n){console.error("Failed to load MSA data from IndexedDB:",n)}finally{e.setLoadingStoredData(!1)}})()}function jN(e){let{rows:t,dataStoreId:r,isStoringData:n}=e;if(t.length>0&&!r&&!n){if(e.msaFilehandle||e.treeFilehandle)return;let o=e.data.msa,i=e.data.tree;(o||i)&&(e.setIsStoringData(!0),(async()=>{try{let s=LN();await PN(s,{msa:o,tree:i,treeMetadata:e.data.treeMetadata})&&e.setDataStoreId(s)}catch(s){console.error("Failed to store MSA data to IndexedDB:",s)}finally{e.setIsStoringData(!1)}})())}}function $N(e){e.orthologParams&&(async()=>{try{e.setProgress("Resolving orthologs"),e.setError(void 0);let t=await SN({self:e});e.setData(t),e.setOrthologParams(void 0)}catch(t){e.setError(t),console.error(t)}finally{e.setProgress("")}})()}function WN(e){e.blastParams&&(async()=>{try{e.setProgress("Submitting query"),e.setError(void 0);let t=await hN({self:e});e.setData(t),e.setBlastParams(void 0)}catch(t){e.setError(t),console.error(t)}finally{e.setProgress("")}})()}function YN(e){let{rows:t,domainsRequested:r,interProAnnotations:n}=e,o=e.data.treeMetadata?.includes('"Accession"')??!1;t.length>0&&o&&!n&&!r&&(e.setDomainsRequested(!0),(async()=>{try{await NN(e)}catch(i){console.error("[msaview-domains] auto-load failed:",i)}finally{e.setProgress("")}})())}function qN(e){let{init:t}=e;if(t){let{msaUrl:r,msaIndexedLocation:n,msaName:o,querySeqName:i}=t;(async()=>{try{if(e.setError(void 0),r){let s=Pw(r);s&&(e.setUniprotId(s),e.setQuerySeqName("query"))}if(i&&e.setQuerySeqName(i),r)e.setMSAFilehandle({uri:r,locationType:"UriLocation"});else if(n&&o){let s=await TN({location:n,name:o});if(s)e.setMSA(s);else throw new Error(`No alignment named ${o} in ${n.uri}`)}e.setInit(void 0)}catch(s){e.setError(s),console.error(s)}})()}}function zN(e){let t=!1;return()=>{let r=RN({model:e});r!==void 0?(e.setMousePos(r),t=!0):t&&(e.setMousePos(void 0),t=!1)}}function JN(e){let t=!1;return()=>{let{connectedViewId:r,transcriptToMsaMap:n,querySeqName:o}=e;if(!r||!n)return;let i=new Set;for(let a of GN((0,HN.getSession)(e).views))for(let c of a.structures){if(c.connectedViewId!==r)continue;let l=c.hoverGenomeHighlights;if(!l||l.length===0)continue;let{g2p:u}=n;for(let d of l)for(let A=d.start;A<d.end;A++){let f=u[A];if(f!==void 0){let g=e.seqPosToGlobalCol(o,f);i.add(g)}}}let s=Array.from(i).map(a=>e.globalColToVisibleCol(a)).filter(a=>a!==void 0);s.length>0?(e.setHighlightedColumns(s),t=!0):t&&(e.setHighlightedColumns(e.highlightColumns?.length?e.highlightColumns:void 0),t=!1)}}function KN(){ON().catch(e=>{console.error("Failed to cleanup old MSA data:",e)})}function hA({model:e,coord:t}){let{querySeqName:r,transcriptToMsaMap:n,mafRegion:o,rows:i}=e,s=i.find(c=>c[0]===r)?.[1];if(!s)return[];let a=UN(s,t);if(a===void 0)return[];if(o){let c=o.start+a;return c<o.end?[{refName:o.refName,start:c,end:c+1}]:[]}if(n){let{refName:c,p2gCodon:l}=n;return Uw(l,a)?.map(([u,d])=>({refName:c,start:u,end:d}))??[]}return[]}function XN(e){let t=hA(e),r=t[0],n=t.at(-1);return r&&n?{refName:r.refName,start:r.start,end:n.end}:void 0}function Ly(){return gt.types.compose(ZN.BaseViewModel,sA(),gt.types.model("MsaView",{connectedViewId:gt.types.maybe(gt.types.string),connectedFeature:gt.types.frozen(),blastParams:gt.types.frozen(),orthologParams:gt.types.frozen(),querySeqName:"QUERY",uniprotId:gt.types.maybe(gt.types.string),zoomToBaseLevel:!1,init:gt.types.frozen(),dataStoreId:gt.types.maybe(gt.types.string),mafRegion:gt.types.frozen()})).volatile(()=>({rid:void 0,progress:"",error:void 0,loadingStoredData:!1,isStoringData:!1,domainsRequested:!1})).views(e=>({getRowByName(t){return e.rows.find(r=>r[0]===t)},getSequenceByRowName(t){return e.rows.find(r=>r[0]===t)?.[1]}})).views(e=>({get transcriptToMsaMap(){return e.connectedFeature?Gw(e.connectedFeature):void 0},get connectedView(){let{views:t}=(0,eL.getSession)(e);return t.find(r=>r.id===e.connectedViewId)}})).views(e=>({get connectedHoverHighlights(){let{mouseCol:t}=e;return t===void 0?[]:hA({model:e,coord:t})},get connectedClickHighlights(){let{mouseClickCol:t}=e;return t===void 0?[]:hA({model:e,coord:t})},get connectedHighlights(){return[...this.connectedHoverHighlights,...this.connectedClickHighlights]}})).actions(e=>({setZoomToBaseLevel(t){e.zoomToBaseLevel=t},setError(t){e.error=t},setProgress(t){e.progress=t},setRid(t){e.rid=t},setBlastParams(t){e.blastParams=t},setOrthologParams(t){e.orthologParams=t},setInit(t){e.init=t},setQuerySeqName(t){e.querySeqName=t},setUniprotId(t){e.uniprotId=t},setDataStoreId(t){e.dataStoreId=t},setMafRegion(t){e.mafRegion=t},setLoadingStoredData(t){e.loadingStoredData=t},setIsStoringData(t){e.isStoringData=t},setDomainsRequested(t){e.domainsRequested=t},handleMsaClick(t){let{connectedView:r,zoomToBaseLevel:n}=e,o=XN({model:e,coord:t});!o||!r||(n?r.navTo(o):r.centerAt(o.start,o.refName))}})).actions(e=>{let t=e.setMouseClickPos.bind(e);return{setMouseClickPos(r,n){t(r,n),r!==void 0&&e.handleMsaClick(r)}}}).views(e=>({extraViewMenuItems(){return[{label:"Zoom to base level on click?",checked:e.zoomToBaseLevel,type:"checkbox",onClick:()=>{e.setZoomToBaseLevel(!e.zoomToBaseLevel)}}]}})).actions(e=>({afterCreate(){KN();for(let t of[VN,jN,WN,$N,qN,YN])(0,gt.addDisposer)(e,(0,yA.autorun)(()=>{t(e)}));(0,gt.addDisposer)(e,(0,yA.autorun)(zN(e))),(0,gt.addDisposer)(e,(0,yA.autorun)(JN(e)))}}))}function ka(e){return e.type==="MsaView"}var e7=(0,Fy.observer)(function({model:e}){let{hovered:t,views:r}=(0,tL.getSession)(e);return r.some(o=>ka(o)&&o.connectedViewId===e.id)&&ui(t)?Py.default.createElement(t7,{model:e,hovered:t}):null}),t7=(0,Fy.observer)(function({model:e,hovered:t}){let{classes:r}=Zu(),{offsetPx:n}=e,{coord:o,refName:i}=t.hoverPosition,s=e.bpToPx({refName:i,coord:o-1}),a=e.bpToPx({refName:i,coord:o});if(s&&a){let c=Math.max(Math.abs(a.offsetPx-s.offsetPx),4),l=Math.min(s.offsetPx,a.offsetPx)-n;return Py.default.createElement("div",{className:r.highlight,style:{left:l,width:c}})}return null}),rL=e7;var _l=p(Q()),nL=p(we()),Oy=p(W());var r7=(0,Oy.observer)(function({model:t}){let{views:r,hovered:n}=(0,nL.getSession)(t),o=r.filter(ka).find(s=>s.connectedViewId===t.id),i=[...o?.connectedClickHighlights??[],...ui(n)?[]:o?.connectedHoverHighlights??[]];return i.length?_l.default.createElement(n7,{model:t,highlights:i}):null}),n7=(0,Oy.observer)(function({model:e,highlights:t}){let{classes:r}=Zu(),{offsetPx:n}=e;return _l.default.createElement(_l.default.Fragment,null,t.map((o,i)=>{let s=e.bpToPx({refName:o.refName,coord:o.start}),a=e.bpToPx({refName:o.refName,coord:o.end});if(s&&a){let c=Math.max(Math.abs(a.offsetPx-s.offsetPx),4),l=Math.min(s.offsetPx,a.offsetPx)-n;return _l.default.createElement("div",{key:`${o.refName}-${o.start}-${o.end}-${i}`,className:r.highlight,style:{left:l,width:c}})}return null}))}),oL=r7;var o7=(0,iL.observer)(function({model:t}){return kl.default.createElement(kl.default.Fragment,null,kl.default.createElement(oL,{model:t}),kl.default.createElement(rL,{model:t}))}),sL=o7;function Gy(e){e.addToExtensionPoint("LinearGenomeView-TracksContainerComponent",(t,{model:r})=>{let{views:n}=(0,cL.getSession)(r);return n.some(i=>ka(i)&&i.connectedViewId===r.id)?[...t,aL.default.createElement(sL,{key:"highlight_protein_viewer_msaview",model:r})]:t})}var gL=p(Pp());var lL=p(as());function Uy(e){let t=e.getAdapterType("BgzipFastaAdapter");return(0,lL.ConfigurationSchema)("BgzipFastaMsaAdapter",{msaRegex:{type:"string",defaultValue:"_"}},{baseConfiguration:t?.configSchema})}function Hy(e){return e.addAdapterType(()=>new gL.AdapterType({name:"BgzipFastaMsaAdapter",configSchema:Uy(e),adapterMetadata:{hiddenFromGUI:!0},getAdapterClass:()=>Promise.resolve().then(()=>(pL(),mL)).then(t=>t.default)}))}var VA=p(we());Ie();var hL=p(O(),1),yL=Y((0,hL.jsx)("path",{d:"M19 13h-6v6h-2v-6H5v-2h6V5h2v6h6z"}),"Add");var wt=p(Q()),nF=p(Ze()),oF=p(we()),zi=p(U());var fe=p(Q()),lx=p(Ze()),Lr=p(U()),nP=p(W()),oP=p(Tt());var xL=p(we());function CL({newViewTitle:e,view:t,feature:r,msaFilehandle:n,treeFilehandle:o,querySeqName:i,data:s}){(0,xL.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,connectedViewId:t.id,connectedFeature:r.toJSON(),msaFilehandle:n,treeFilehandle:o,querySeqName:i,data:s})}var Vy=p(Q()),bL=p(U());function i7({children:e,...t}){return Vy.default.createElement("div",null,Vy.default.createElement(bL.TextField,{...t},e))}var ct=i7;var jy=p(Q()),EL=p(Ze()),wL=p(U()),IL=p(Tt()),s7=(0,IL.makeStyles)()({dialogContent:{width:"80em"}});function pr({error:e,children:t}){let{classes:r}=s7();return jy.default.createElement(wL.DialogContent,{className:r.dialogContent},e?jy.default.createElement(EL.ErrorMessage,{error:e}):null,t)}var CA=p(Q()),Dl=p(U());function rn({onSubmit:e,onCancel:t,submitDisabled:r,submitLabel:n="Submit",cancelLabel:o="Cancel"}){return CA.default.createElement(Dl.DialogActions,null,CA.default.createElement(Dl.Button,{color:"primary",variant:"contained",disabled:r,onClick:()=>{e()}},n),CA.default.createElement(Dl.Button,{color:"secondary",variant:"contained",onClick:()=>{t()}},o))}var nn=p(Q()),Da=p(U()),BL=p(Tt());var SL=p(Q()),vL=p(Tt());var a7=(0,vL.makeStyles)()({textAreaFont:{fontFamily:"Courier New"}});function $y({value:e}){let{classes:t}=a7();return SL.default.createElement(ct,{variant:"outlined",multiline:!0,minRows:5,maxRows:10,fullWidth:!0,value:e,slotProps:{input:{readOnly:!0,classes:{input:t.textAreaFont}}}})}var c7=(0,BL.makeStyles)()({flex:{display:"flex"},minWidth:{minWidth:300},centered:{alignContent:"center",marginLeft:20}});function gr({feature:e,options:t,selectedId:r,selectedTranscript:n,setSelectedId:o,proteinSequence:i,validIds:s}){let{classes:a}=c7(),[c,l]=(0,nn.useState)(!1);return nn.default.createElement(nn.default.Fragment,null,nn.default.createElement("div",{className:a.flex},nn.default.createElement(Da.TextField,{variant:"outlined",label:`Choose isoform of ${io(e)}`,helperText:"the query row, so the alignment stays linked to the genome view",select:!0,className:a.minWidth,value:r,onChange:u=>{o(u.target.value)}},t.map(u=>{let d=s?s.some(g=>Ta(u,g)):!0,{len:A,mod:f}=aA(u);return nn.default.createElement(Da.MenuItem,{value:Hi(u),key:u.id(),disabled:!d},Ma(u)," (",A," aa)"," ",f?" (possible fragment)":"",s?d?" (has data)":" (no data)":"")})),nn.default.createElement("div",{className:a.centered},nn.default.createElement(Da.Button,{variant:"contained",color:"primary",onClick:()=>{l(!c)}},c?"Hide sequence":"Show sequence"))),c?nn.default.createElement($y,{value:i?`>${Ma(n)}
-${i}`:"Loading..."}):null)}var NA=p(Q());var bA=p(we());oQ();function TL({cds:e,sequence:t,codonTable:r}){let n=e[0]?.phase??0,o=nQ(e,t),i=n>0?"&":"";for(let s=n;s<o.length;s+=3)i+=r[o.slice(s,s+3)]||"&";return i}var l7=[{id:1,name:"Standard",ncbieaa:"FFLLSSSSYY**CC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"---M------**--*----M---------------M----------------------------"},{id:2,name:"Vertebrate Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNKKSS**VVVVAAAADDEEGGGG",sncbieaa:"----------**--------------------MMMM----------**---M------------"},{id:3,name:"Yeast Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWTTTTPPPPHHQQRRRRIIMMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**----------------------MM---------------M------------"},{id:4,name:"Mold Mitochondrial; Protozoan Mitochondrial; Coelenterate Mitochondrial; Mycoplasma; Spiroplasma",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--MM------**-------M------------MMMM---------------M------------"},{id:5,name:"Invertebrate Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNKKSSSSVVVVAAAADDEEGGGG",sncbieaa:"---M------**--------------------MMMM---------------M------------"},{id:6,name:"Ciliate Nuclear; Dasycladacean Nuclear; Hexamita Nuclear",ncbieaa:"FFLLSSSSYYQQCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--------------*--------------------M----------------------------"},{id:9,name:"Echinoderm Mitochondrial; Flatworm Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNNKSSSSVVVVAAAADDEEGGGG",sncbieaa:"----------**-----------------------M---------------M------------"},{id:10,name:"Euplotid Nuclear",ncbieaa:"FFLLSSSSYY**CCCWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**-----------------------M----------------------------"},{id:11,name:"Bacterial, Archaeal and Plant Plastid",ncbieaa:"FFLLSSSSYY**CC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"---M------**--*----M------------MMMM---------------M------------"},{id:12,name:"Alternative Yeast Nuclear",ncbieaa:"FFLLSSSSYY**CC*WLLLSPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**--*----M---------------M----------------------------"},{id:13,name:"Ascidian Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNKKSSGGVVVVAAAADDEEGGGG",sncbieaa:"---M------**----------------------MM---------------M------------"},{id:14,name:"Alternative Flatworm Mitochondrial",ncbieaa:"FFLLSSSSYYY*CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNNKSSSSVVVVAAAADDEEGGGG",sncbieaa:"-----------*-----------------------M----------------------------"},{id:15,name:"Blepharisma Macronuclear",ncbieaa:"FFLLSSSSYY*QCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------*---*--------------------M----------------------------"},{id:16,name:"Chlorophycean Mitochondrial",ncbieaa:"FFLLSSSSYY*LCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------*---*--------------------M----------------------------"},{id:21,name:"Trematode Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNNKSSSSVVVVAAAADDEEGGGG",sncbieaa:"----------**-----------------------M---------------M------------"},{id:22,name:"Scenedesmus obliquus Mitochondrial",ncbieaa:"FFLLSS*SYY*LCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"------*---*---*--------------------M----------------------------"},{id:23,name:"Thraustochytrium Mitochondrial",ncbieaa:"FF*LSSSSYY**CC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--*-------**--*-----------------M--M---------------M------------"},{id:24,name:"Rhabdopleuridae Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSSKVVVVAAAADDEEGGGG",sncbieaa:"---M------**-------M---------------M---------------M------------"},{id:25,name:"Candidate Division SR1 and Gracilibacteria",ncbieaa:"FFLLSSSSYY**CCGWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"---M------**-----------------------M---------------M------------"},{id:26,name:"Pachysolen tannophilus Nuclear",ncbieaa:"FFLLSSSSYY**CC*WLLLAPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**--*----M---------------M----------------------------"},{id:27,name:"Karyorelict Nuclear",ncbieaa:"FFLLSSSSYYQQCCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--------------*--------------------M----------------------------"},{id:28,name:"Condylostoma Nuclear",ncbieaa:"FFLLSSSSYYQQCCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**--*--------------------M----------------------------"},{id:29,name:"Mesodinium Nuclear",ncbieaa:"FFLLSSSSYYYYCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--------------*--------------------M----------------------------"},{id:30,name:"Peritrich Nuclear",ncbieaa:"FFLLSSSSYYEECC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--------------*--------------------M----------------------------"},{id:31,name:"Blastocrithidia Nuclear",ncbieaa:"FFLLSSSSYYEECCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**-----------------------M----------------------------"},{id:32,name:"Balanophoraceae Plastid",ncbieaa:"FFLLSSSSYY*WCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"---M------*---*----M------------MMMM---------------M------------"},{id:33,name:"Cephalodiscidae Mitochondrial",ncbieaa:"FFLLSSSSYYY*CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSSKVVVVAAAADDEEGGGG",sncbieaa:"---M-------*-------M---------------M---------------M------------"}],u7="TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG",f7="TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG",d7="TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG",A7=Array.from({length:64},(e,t)=>u7[t]+f7[t]+d7[t]),ML=new Map(l7.map(e=>[e.id,e]));function m7(e){let t={};for(let[r,n]of Object.entries(e)){let o=i=>{let s=r.charAt(i);return[s.toUpperCase(),s.toLowerCase()]};for(let i of o(0))for(let s of o(1))for(let a of o(2))t[i+s+a]=n}return t}function p7(e){let t=ML.get(e);!t&&e!==1&&console.warn(`Unknown genetic code (transl_table=${e}); using standard code`);let{id:r,name:n,ncbieaa:o,sncbieaa:i}=t??ML.get(1),s={},a=[];for(let[c,l]of A7.entries())s[l]=o[c],i[c]==="M"&&a.push(l);return{id:r,name:n,codonTable:m7(s),starts:a}}var RL=new Map;function QL(e=1){let t=RL.get(e);return t||(t=p7(e),RL.set(e,t)),t}function Wy(e){let t=Array.isArray(e)?e[0]:e,r=Number(t);return Number.isInteger(r)&&r>0?r:void 0}function g7({cds:e,sequence:t,geneticCodeId:r}){let{codonTable:n}=QL(r);return TL({cds:e,sequence:t,codonTable:n})}function h7(e,t){return e.map(r=>({...r,start:t-r.end,end:t-r.start})).toSorted((r,n)=>r.start-n.start)}function _L({feature:e,seq:t}){let{subfeatures:r,start:n,strand:o}=e.toJSON(),i=(0,bA.dedupe)(r?.toSorted((c,l)=>c.start-l.start).map(c=>({...c,start:c.start-n,end:c.end-n})).filter(c=>c.type==="CDS")??[],c=>`${c.start}-${c.end}`),s=e.get("subfeatures")?.find(c=>c.get("type")?.toLowerCase()==="cds"),a=Wy(e.get("transl_table"))??Wy(s?.get("transl_table"));return g7({cds:o===-1?h7(i,t.length):i,sequence:o===-1?(0,bA.revcom)(t):t,geneticCodeId:a})}var eP=p(we());var lt=p(Q(),1),cx=p(LL(),1);var Et=p(Q(),1);var Yo={};Bt(Yo,{ERROR_REVALIDATE_EVENT:()=>B7,FOCUS_EVENT:()=>PL,MUTATE_EVENT:()=>OL,RECONNECT_EVENT:()=>FL});var PL=0,FL=1,OL=2,B7=3;var GL=Object.prototype.hasOwnProperty;function EA(e,t){var r,n;if(e===t)return!0;if(e&&t&&(r=e.constructor)===t.constructor){if(r===Date)return e.getTime()===t.getTime();if(r===RegExp)return e.toString()===t.toString();if(r===Array){if((n=e.length)===t.length)for(;n--&&EA(e[n],t[n]););return n===-1}if(!r||typeof e=="object"){n=0;for(r in e)if(GL.call(e,r)&&++n&&!GL.call(t,r)||!(r in t)||!EA(e[r],t[r]))return!1;return Object.keys(t).length===n}}return e!==e&&t!==t}var on=new WeakMap,sn=()=>{},ot=sn(),La=Object,ee=e=>e===ot,hr=e=>typeof e=="function",an=(e,t)=>({...e,...t}),TA=e=>hr(e.then),qy={},wA={},tx="undefined",Pa=typeof window!=tx,SA=typeof document!=tx,HL=Pa&&"Deno"in window,VL=()=>Pa&&typeof window.requestAnimationFrame!=tx,MA=(e,t)=>{let r=on.get(e);return[()=>!ee(t)&&e.get(t)||qy,n=>{if(!ee(t)){let o=e.get(t);t in wA||(wA[t]=o),r[5](t,an(o,n),o||qy)}},r[6],()=>!ee(t)&&t in wA?wA[t]:!ee(t)&&e.get(t)||qy]},Ky=!0,T7=()=>Ky,[Xy,Zy]=Pa&&window.addEventListener?[window.addEventListener.bind(window),window.removeEventListener.bind(window)]:[sn,sn],M7=()=>{let e=SA&&document.visibilityState;return ee(e)||e!=="hidden"},R7=e=>(SA&&document.addEventListener("visibilitychange",e),Xy("focus",e),()=>{SA&&document.removeEventListener("visibilitychange",e),Zy("focus",e)}),Q7=e=>{let t=()=>{Ky=!0,e()},r=()=>{Ky=!1};return Xy("online",t),Xy("offline",r),()=>{Zy("online",t),Zy("offline",r)}},jL={isOnline:T7,isVisible:M7},$L={initFocus:R7,initReconnect:Q7},RA=!Et.default.useId,qo=!Pa||HL,rx=e=>VL()?window.requestAnimationFrame(e):setTimeout(e,1),Fa=qo?Et.useEffect:Et.useLayoutEffect,zy=typeof navigator<"u"&&navigator.connection,ex=!qo&&zy&&(["slow-2g","2g"].includes(zy.effectiveType)||zy.saveData),IA=new WeakMap,_7=e=>La.prototype.toString.call(e),Jy=(e,t)=>e===`[object ${t}]`,k7=0,vA=e=>{let t=typeof e,r=_7(e),n=Jy(r,"Date"),o=Jy(r,"RegExp"),i=Jy(r,"Object"),s,a;if(La(e)===e&&!n&&!o){if(s=IA.get(e),s)return s;if(s=++k7+"~",IA.set(e,s),Array.isArray(e)){for(s="@",a=0;a<e.length;a++)s+=vA(e[a])+",";IA.set(e,s)}if(i){s="#";let c=La.keys(e).sort();for(;!ee(a=c.pop());)ee(e[a])||(s+=a+":"+vA(e[a])+",");IA.set(e,s)}}else s=n?e.toJSON():t=="symbol"?e.toString():t=="string"?JSON.stringify(e):""+e;return s},Ll=e=>{if(hr(e))try{e=e()}catch{e=""}let t=e;return e=typeof e=="string"?e:(Array.isArray(e)?e.length:e)?vA(e):"",[e,t]},D7=0,Nl=()=>++D7;async function QA(...e){let[t,r,n,o]=e,i=an({populateCache:!0,throwOnError:!0},typeof o=="boolean"?{revalidate:o}:o||{}),s=i.populateCache,a=i.rollbackOnError,c=i.optimisticData,l=A=>typeof a=="function"?a(A):a!==!1,u=i.throwOnError;if(hr(r)){let A=r,f=[],g=t.keys();for(let h of g)!/^\$(inf|sub)\$/.test(h)&&A(t.get(h)._k)&&f.push(h);return Promise.all(f.map(d))}return d(r);async function d(A){let[f]=Ll(A);if(!f)return;let[g,h]=MA(t,f),[y,E,x,S]=on.get(t),w=()=>{let k=y[f];return(hr(i.revalidate)?i.revalidate(g().data,A):i.revalidate!==!1)&&(delete x[f],delete S[f],k&&k[0])?k[0](2).then(()=>g().data):g().data};if(e.length<3)return w();let I=n,v,B=!1,R=Nl();E[f]=[R,0];let D=!ee(c),L=g(),F=L.data,C=L._c,M=ee(C)?F:C;if(D&&(c=hr(c)?c(M,F):c,h({data:c,_c:M})),hr(I))try{I=I(M)}catch(k){v=k,B=!0}if(I&&TA(I))if(I=await I.catch(k=>{v=k,B=!0}),R!==E[f][0]){if(B)throw v;return I}else B&&D&&l(v)&&(s=!0,h({data:M,_c:ot}));if(s&&!B)if(hr(s)){let k=s(I,M);h({data:k,error:ot,_c:ot})}else h({data:I,error:ot,_c:ot});if(E[f][1]=Nl(),Promise.resolve(w()).then(()=>{h({_c:ot})}),B){if(u)throw v;return}return I}}var UL=(e,t)=>{for(let r in e)e[r][0]&&e[r][0](t)},nx=(e,t)=>{if(!on.has(e)){let r=an($L,t),n=Object.create(null),o=QA.bind(ot,e),i=sn,s=Object.create(null),a=(u,d)=>{let A=s[u]||[];return s[u]=A,A.push(d),()=>{let f=A.indexOf(d);f>=0&&(A[f]=A[A.length-1],A.pop())}},c=(u,d,A)=>{e.set(u,d);let f=s[u];if(f)for(let g of f)g(d,A)},l=()=>{if(!on.has(e)&&(on.set(e,[n,Object.create(null),Object.create(null),Object.create(null),o,c,a]),!qo)){let u=r.initFocus(setTimeout.bind(ot,UL.bind(ot,n,0))),d=r.initReconnect(setTimeout.bind(ot,UL.bind(ot,n,1)));i=()=>{u&&u(),d&&d(),on.delete(e)}}};return l(),[e,o,l,i]}return[e,on.get(e)[4]]},N7=(e,t,r,n,o)=>{let i=r.errorRetryCount,s=o.retryCount,a=~~((Math.random()+.5)*(1<<(s<8?s:8)))*r.errorRetryInterval;!ee(i)&&s>i||setTimeout(n,a,o)},WL=EA,[_A,YL]=nx(new Map),kA=an({onLoadingSlow:sn,onSuccess:sn,onError:sn,onErrorRetry:N7,onDiscarded:sn,revalidateOnFocus:!0,revalidateOnReconnect:!0,revalidateIfStale:!0,shouldRetryOnError:!0,errorRetryInterval:ex?1e4:5e3,focusThrottleInterval:5*1e3,dedupingInterval:2*1e3,loadingTimeout:ex?5e3:3e3,compare:WL,isPaused:()=>!1,cache:_A,mutate:YL,fallback:{}},jL),ox=(e,t)=>{let r=an(e,t);if(t){let{use:n,fallback:o}=e,{use:i,fallback:s}=t;n&&i&&(r.use=n.concat(i)),o&&s&&(r.fallback=an(o,s))}return r},BA=(0,Et.createContext)({}),ix=e=>{let{value:t}=e,r=(0,Et.useContext)(BA),n=hr(t),o=(0,Et.useMemo)(()=>n?t(r):t,[n,r,t]),i=(0,Et.useMemo)(()=>n?o:ox(r,o),[n,r,o]),s=o&&o.provider,a=(0,Et.useRef)(ot);s&&!a.current&&(a.current=nx(s(i.cache||_A),o));let c=a.current;return c&&(i.cache=c[0],i.mutate=c[1]),Fa(()=>{if(c)return c[2]&&c[2](),c[3]},[]),(0,Et.createElement)(BA.Provider,an(e,{value:i}))};var qL="$inf$";var Oa=p(Q(),1);var zL=Pa&&window.__SWR_DEVTOOLS_USE__,L7=zL?window.__SWR_DEVTOOLS_USE__:[],P7=()=>{zL&&(window.__SWR_DEVTOOLS_REACT__=Oa.default)},F7=e=>hr(e[1])?[e[0],e[1],e[2]||{}]:[e[0],null,(e[1]===null?e[2]:e[1])||{}],O7=()=>{let e=(0,Oa.useContext)(BA);return(0,Oa.useMemo)(()=>an(kA,e),[e])};var G7=e=>(t,r,n)=>e(t,r&&((...i)=>{let[s]=Ll(t),[,,,a]=on.get(_A);if(s.startsWith(qL))return r(...i);let c=a[s];return ee(c)?r(...i):(delete a[s],c)}),n),U7=L7.concat(G7),JL=e=>function(...r){let n=O7(),[o,i,s]=F7(r),a=ox(n,s),c=e,{use:l}=a,u=(l||[]).concat(U7);for(let d=u.length;d--;)c=u[d](c);return c(o,i||a.fetcher||null,a)},KL=(e,t,r)=>{let n=t[e]||(t[e]=[]);return n.push(r),()=>{let o=n.indexOf(r);o>=0&&(n[o]=n[n.length-1],n.pop())}};P7();var H7=()=>{},uhe=H7();var sx=lt.default.use||(e=>{switch(e.status){case"pending":throw e;case"fulfilled":return e.value;case"rejected":throw e.reason;default:throw e.status="pending",e.then(t=>{e.status="fulfilled",e.value=t},t=>{e.status="rejected",e.reason=t}),e}}),ax={dedupe:!0},DA=Promise.resolve(ot);DA.status="fulfilled";DA.value=ot;var V7=()=>sn,j7=(e,t,r)=>{let{cache:n,compare:o,suspense:i,fallbackData:s,revalidateOnMount:a,revalidateIfStale:c,refreshInterval:l,refreshWhenHidden:u,refreshWhenOffline:d,keepPreviousData:A,strictServerPrefetchWarning:f}=r,[g,h,y,E]=on.get(n),[x,S]=Ll(e),w=(0,lt.useRef)(!1),I=(0,lt.useRef)(!1),v=(0,lt.useRef)(x),B=(0,lt.useRef)(t),R=(0,lt.useRef)(r),D=()=>R.current,L=()=>D().isVisible()&&D().isOnline(),[F,C,M,k]=MA(n,x),G=(0,lt.useRef)({}).current,j=ee(s)?ee(r.fallback)?ot:r.fallback[x]:s,oe=(Ae,ae)=>{for(let De in G){let Te=De;if(Te==="data"){if(!o(Ae[Te],ae[Te])&&(!ee(Ae[Te])||!o(Ki,ae[Te])))return!1}else if(ae[Te]!==Ae[Te])return!1}return!0},te=!w.current,Gr=(0,lt.useMemo)(()=>{let Ae=F(),ae=k(),De=ye=>{let Je=an(ye);return delete Je._k,(()=>{if(!x||!t||D().isPaused())return!1;if(te&&!ee(a))return a;let On=ee(j)?Je.data:j;return i?ee(On)||c:ee(On)||c})()?{isValidating:!0,isLoading:!0,...Je}:Je},Te=De(Ae),rr=Ae===ae?Te:De(ae),Pt=Te;return[()=>{let ye=De(F());return oe(ye,Pt)?(Pt.data=ye.data,Pt.isLoading=ye.isLoading,Pt.isValidating=ye.isValidating,Pt.error=ye.error,Pt):(Pt=ye,ye)},()=>rr]},[n,x]),it=(0,cx.useSyncExternalStore)((0,lt.useCallback)(Ae=>M(x,(ae,De)=>{oe(De,ae)||Ae()}),[n,x]),Gr[0],Gr[1]),de=g[x]&&g[x].length>0,Ur=it.data,xr=ee(Ur)?j&&TA(j)?sx(j):j:Ur,un=it.error,Pn=(0,lt.useRef)(xr),Ki=A?ee(Ur)?ee(Pn.current)?xr:Pn.current:Ur:xr,Fn=x&&ee(xr),co=(0,lt.useRef)(null);!qo&&(0,cx.useSyncExternalStore)(V7,()=>(co.current=!1,co),()=>(co.current=!0,co));let YA=co.current;f&&YA&&!i&&Fn&&console.warn(`Missing pre-initiated data for serialized key "${x}" during server-side rendering. Data fetching should be initiated on the server and provided to SWR via fallback data. You can set "strictServerPrefetchWarning: false" to disable this warning.`);let Ha=!x||!t||D().isPaused()||de&&!ee(un)?!1:te&&!ee(a)?a:i?ee(xr)?!1:c:ee(xr)||c,ve=te&&Ha,Ol=ee(it.isValidating)?ve:it.isValidating,ke=ee(it.isLoading)?ve:it.isLoading,lo=(0,lt.useCallback)(async Ae=>{let ae=B.current;if(!x||!ae||I.current||D().isPaused())return!1;let De,Te,rr=!0,Pt=Ae||{},ye=!y[x]||!Pt.dedupe,Je=()=>RA?!I.current&&x===v.current&&w.current:x===v.current,nr={isValidating:!1,isLoading:!1},On=()=>{C(nr)},Zi=()=>{let It=y[x];It&&It[1]===Te&&delete y[x]},es={isValidating:!0};ee(F().data)&&(es.isLoading=!0);try{if(ye&&(C(es),r.loadingTimeout&&ee(F().data)&&setTimeout(()=>{rr&&Je()&&D().onLoadingSlow(x,r)},r.loadingTimeout),y[x]=[ae(S),Nl()]),[De,Te]=y[x],De=await De,ye&&setTimeout(Zi,r.dedupingInterval),!y[x]||y[x][1]!==Te)return ye&&Je()&&D().onDiscarded(x),!1;nr.error=ot;let It=h[x];if(!ee(It)&&(Te<=It[0]||Te<=It[1]||It[1]===0))return On(),ye&&Je()&&D().onDiscarded(x),!1;let St=F().data;nr.data=o(St,De)?St:De,ye&&Je()&&D().onSuccess(De,x,r)}catch(It){Zi();let St=D(),{shouldRetryOnError:uo}=St;St.isPaused()||(nr.error=It,ye&&Je()&&(St.onError(It,x,St),(uo===!0||hr(uo)&&uo(It))&&(!D().revalidateOnFocus||!D().revalidateOnReconnect||L())&&St.onErrorRetry(It,x,St,ts=>{let rs=g[x];rs&&rs[0]&&rs[0](Yo.ERROR_REVALIDATE_EVENT,ts)},{retryCount:(Pt.retryCount||0)+1,dedupe:!0})))}return rr=!1,On(),!0},[x,n]),Be=(0,lt.useCallback)((...Ae)=>QA(n,v.current,...Ae),[]);if(Fa(()=>{B.current=t,R.current=r,ee(Ur)||(Pn.current=Ur)}),Fa(()=>{if(!x)return;let Ae=lo.bind(ot,ax),ae=0;D().revalidateOnFocus&&(ae=Date.now()+D().focusThrottleInterval);let Te=KL(x,g,(rr,Pt={})=>{if(rr==Yo.FOCUS_EVENT){let ye=Date.now();D().revalidateOnFocus&&ye>ae&&L()&&(ae=ye+D().focusThrottleInterval,Ae())}else if(rr==Yo.RECONNECT_EVENT)D().revalidateOnReconnect&&L()&&Ae();else{if(rr==Yo.MUTATE_EVENT)return lo();if(rr==Yo.ERROR_REVALIDATE_EVENT)return lo(Pt)}});return I.current=!1,v.current=x,w.current=!0,C({_k:S}),Ha&&(y[x]||(ee(xr)||qo?Ae():rx(Ae))),()=>{I.current=!0,Te()}},[x]),Fa(()=>{let Ae;function ae(){let Te=hr(l)?l(F().data):l;Te&&Ae!==-1&&(Ae=setTimeout(De,Te))}function De(){!F().error&&(u||D().isVisible())&&(d||D().isOnline())?lo(ax).then(ae):ae()}return ae(),()=>{Ae&&(clearTimeout(Ae),Ae=-1)}},[l,u,d,x]),(0,lt.useDebugValue)(Ki),i){if(!RA&&qo&&Fn)throw new Error("Fallback data is required when using Suspense in SSR.");Fn&&(B.current=t,R.current=r,I.current=!1);let Ae=E[x],ae=!ee(Ae)&&Fn?Be(Ae):DA;if(sx(ae),!ee(un)&&Fn)throw un;let De=Fn?lo(ax):DA;!ee(Ki)&&Fn&&(De.status="fulfilled",De.value=!0),sx(De)}return{mutate:Be,get data(){return G.data=!0,Ki},get error(){return G.error=!0,un},get isValidating(){return G.isValidating=!0,Ol},get isLoading(){return G.isLoading=!0,ke}}},fhe=La.defineProperty(ix,"defaultValue",{value:kA}),$i=JL(j7);var XL=p(as());async function ZL({start:e,end:t,refName:r,session:n,assemblyName:o}){let{assemblyManager:i,rpcManager:s}=n,a=await i.waitForAssembly(o);if(!a)throw new Error("assembly not found");let c="getSequence";return(await s.call(c,"CoreGetFeatures",{adapterConfig:(0,XL.getConf)(a,["sequence","adapter"]),sessionId:c,regions:[{start:e,end:t,refName:a.getCanonicalRefName(r),assemblyName:o}]}))[0]?.get("seq")??""}var Wi={revalidateOnFocus:!1,revalidateOnReconnect:!1,revalidateIfStale:!1,refreshWhenHidden:!1,refreshWhenOffline:!1,shouldRetryOnError:!1};async function $7({feature:e,assemblyName:t,view:r}){let n=(0,eP.getSession)(r),{start:o,end:i,refName:s}=e.toJSON();return{seq:await ZL({start:o,end:i,refName:s,assemblyName:t,session:n})}}function tP({view:e,feature:t}){let r=e?.assemblyNames?.[0],n=t&&r?{feature:t,assemblyName:r,view:e}:void 0,{data:o,error:i}=$i(n?[n.feature.id(),n.assemblyName,"feature-sequence"]:null,()=>$7(n),Wi);return{sequence:o,error:i}}function rP({view:e,feature:t}){let{sequence:r,error:n}=tP({view:e,feature:t});return{proteinSequence:r&&t?_L({seq:r.seq,feature:t}):"",sequence:r,error:n}}function W7(e,t,r){if(!r?.length)return e;let n=s=>r.some(a=>Ta(s,a)),o=t.find(s=>Hi(s)===e);if(o&&n(o))return e;let i=t.find(n);return i?Hi(i):e}function Nr({feature:e,view:t,validIds:r}){let n=(0,NA.useMemo)(()=>uA(e),[e]),[o,i]=(0,NA.useState)(()=>Hi(n[0])),s=W7(o,n,r),a=n.find(u=>Hi(u)===s),{proteinSequence:c,error:l}=rP({view:t,feature:a});return{options:n,selectedId:s,setSelectedId:i,selectedTranscript:a,proteinSequence:c,error:l,validIds:r}}var Y7=(0,oP.makeStyles)()({textAreaFont:{fontFamily:"Courier New"},inputContainer:{marginBottom:30},fileContainer:{maxWidth:500},msaInput:{marginBottom:20},queryNameInput:{marginTop:20},warningAlert:{marginTop:10}}),q7=(0,nP.observer)(function({model:t,feature:r,handleClose:n}){let o=tr(t),{classes:i}=Y7(),[s,a]=(0,fe.useState)(),[c,l]=(0,fe.useState)("file"),[u,d]=(0,fe.useState)(""),[A,f]=(0,fe.useState)(""),[g,h]=(0,fe.useState)(),[y,E]=(0,fe.useState)(),[x,S]=(0,fe.useState)(""),w=Nr({feature:r,view:o}),{selectedTranscript:I,error:v}=w;return fe.default.createElement(fe.default.Fragment,null,fe.default.createElement(pr,{error:s??v},fe.default.createElement(Lr.FormControl,{component:"fieldset"},fe.default.createElement(Lr.RadioGroup,{row:!0,value:c,onChange:R=>{l(R.target.value)}},fe.default.createElement(Lr.FormControlLabel,{value:"file",control:fe.default.createElement(Lr.Radio,null),label:"Open files"}),fe.default.createElement(Lr.FormControlLabel,{value:"text",control:fe.default.createElement(Lr.Radio,null),label:"Paste text"}))),fe.default.createElement("div",{className:i.inputContainer},c==="file"?fe.default.createElement("div",{className:i.fileContainer},fe.default.createElement(lx.FileSelector,{name:"MSA File .aln (Clustal), .fa/.mfa (aligned FASTA), .stock (Stockholm), etc)",inline:!0,location:g,setLocation:h}),fe.default.createElement(lx.FileSelector,{name:"Tree file .nh (Newick) or .asn (NCBI COBALT ASN.1)",inline:!0,location:y,setLocation:E})):fe.default.createElement(fe.default.Fragment,null,fe.default.createElement(ct,{variant:"outlined",name:"MSA",multiline:!0,minRows:5,className:i.msaInput,maxRows:10,fullWidth:!0,placeholder:"Paste MSA here",value:u,onChange:R=>{d(R.target.value)}}),fe.default.createElement(ct,{variant:"outlined",name:"Tree",multiline:!0,minRows:5,maxRows:10,fullWidth:!0,placeholder:"Paste newick tree (optional)",value:A,onChange:R=>{f(R.target.value)}}))),fe.default.createElement(gr,{feature:r,...w}),fe.default.createElement(ct,{variant:"outlined",name:"MSA row name",fullWidth:!0,required:!0,className:i.queryNameInput,placeholder:"Row name in MSA that corresponds to the selected transcript",helperText:"Required: Specify the name of the row in your MSA that should be aligned with the selected transcript",value:x,onChange:R=>{S(R.target.value)}}),x.trim()?null:fe.default.createElement(Lr.Alert,{severity:"warning",className:i.warningAlert},"Without specifying the MSA row name, clicking on the MSA will not navigate to the corresponding genome position, and hovering highlights will not work.")),fe.default.createElement(rn,{submitDisabled:!I||c==="file"&&!g||c==="text"&&!u.trim(),onSubmit:()=>{try{I&&(a(void 0),CL({newViewTitle:io(I),view:o,feature:I,querySeqName:x.trim(),...c==="file"?{msaFilehandle:g,treeFilehandle:y}:{data:{msa:u,tree:A}}}),n())}catch(R){console.error(R),a(R)}},onCancel:n}))}),iP=q7;var ln=p(Q());Ie();var sP=p(O(),1),aP=Y((0,sP.jsx)("path",{d:"M19.14 12.94c.04-.3.06-.61.06-.94 0-.32-.02-.64-.07-.94l2.03-1.58c.18-.14.23-.41.12-.61l-1.92-3.32c-.12-.22-.37-.29-.59-.22l-2.39.96c-.5-.38-1.03-.7-1.62-.94l-.36-2.54c-.04-.24-.24-.41-.48-.41h-3.84c-.24 0-.43.17-.47.41l-.36 2.54c-.59.24-1.13.57-1.62.94l-2.39-.96c-.22-.08-.47 0-.59.22L2.74 8.87c-.12.21-.08.47.12.61l2.03 1.58c-.05.3-.09.63-.09.94s.02.64.07.94l-2.03 1.58c-.18.14-.23.41-.12.61l1.92 3.32c.12.22.37.29.59.22l2.39-.96c.5.38 1.03.7 1.62.94l.36 2.54c.05.24.24.41.48.41h3.84c.24 0 .44-.17.47-.41l.36-2.54c.59-.24 1.13-.56 1.62-.94l2.39.96c.22.08.47 0 .59-.22l1.92-3.32c.12-.22.07-.47-.12-.61zM12 15.6c-1.98 0-3.6-1.62-3.6-3.6s1.62-3.6 3.6-3.6 3.6 1.62 3.6 3.6-1.62 3.6-3.6 3.6"}),"Settings");var PP=p(U()),FP=p(Tt());var Ee=p(Q());oy();var yr=p(U()),CP=p(W()),bP=p(Tt());var ht=p(Q()),dP=p(Ze());Ie();var cP=p(O(),1),lP=Y((0,cP.jsx)("path",{d:"M6 19c0 1.1.9 2 2 2h8c1.1 0 2-.9 2-2V7H6zM19 4h-3.5l-1-1h-5l-1 1H5v2h14z"}),"Delete");var Dt=p(U()),AP=p(W()),mP=p(Tt());var ux=p(we());function LA({newViewTitle:e,view:t,feature:r,blastParams:n}){(0,ux.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,connectedViewId:t.id,connectedFeature:r.toJSON(),drawNodeBubbles:!0,colWidth:10,rowHeight:12,blastParams:n})}function uP({newViewTitle:e,view:t,cached:r,connectedFeature:n}){(0,ux.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,connectedViewId:t.id,connectedFeature:n,drawNodeBubbles:!0,colWidth:10,rowHeight:12,data:{msa:r.msa,tree:r.tree,treeMetadata:r.treeMetadata}})}function PA(e){let{data:t,error:r,isLoading:n,mutate:o}=$i(`cached-blast-${e.join(",")}`,async()=>(await fN()).filter(c=>c.geneId&&e.includes(c.geneId)),Wi);return{results:t??[],error:r,isLoading:n,handleDelete:async a=>{await Ry(a),await o(c=>c?.filter(l=>l.id!==a)??[],!1)},handleClearAll:async()=>{await Promise.all((t??[]).map(a=>Ry(a.id))),await o([],!1)}}}var z7=(0,mP.makeStyles)()({header:{display:"flex",justifyContent:"space-between",alignItems:"center",marginBottom:8},resultList:{maxHeight:300,overflow:"auto"}});function fP(e){let t=[e.geneName,e.transcriptName!==e.geneName?e.transcriptName:void 0].filter(r=>!!r);return t.length>0?t.join(" - "):e.geneId??e.transcriptId??"Unknown"}var J7=(0,AP.observer)(function({model:e,handleClose:t,feature:r}){let{classes:n}=z7(),o=tr(e),[i,s]=(0,ht.useState)(),a=(0,ht.useMemo)(()=>Qa(r),[r]),{results:c,error:l,isLoading:u,handleDelete:d,handleClearAll:A}=PA(a),f=h=>{let{transcriptId:y}=h,E=y?uA(r).find(x=>Ta(x,y)):void 0;uP({view:o,cached:h,newViewTitle:`BLAST - ${fP(h)}`,connectedFeature:E?.toJSON()}),t()},g=l??i;return g?ht.default.createElement(dP.ErrorMessage,{error:g}):u?ht.default.createElement(Dt.Typography,null,"Loading cached results..."):c.length===0?ht.default.createElement(Dt.Typography,{color:"textSecondary"},"No cached BLAST results found for this gene. Run a BLAST query to cache results."):ht.default.createElement("div",null,ht.default.createElement("div",{className:n.header},ht.default.createElement(Dt.Typography,{variant:"subtitle1"},"Cached BLAST Results (",c.length,")"),ht.default.createElement(Dt.Button,{size:"small",color:"error",onClick:async()=>{try{s(void 0),await A()}catch(h){s(h)}}},"Clear results for this gene")),ht.default.createElement(Dt.List,{dense:!0,className:n.resultList},c.map(h=>ht.default.createElement(Dt.ListItem,{key:h.id,disablePadding:!0,secondaryAction:ht.default.createElement(Dt.IconButton,{edge:"end",size:"small",onClick:async y=>{y.stopPropagation();try{s(void 0),await d(h.id)}catch(E){s(E)}}},ht.default.createElement(lP,{fontSize:"small"}))},ht.default.createElement(Dt.ListItemButton,{onClick:()=>{f(h)}},ht.default.createElement(Dt.ListItemText,{primary:`${fP(h)} - ${h.blastDatabase}/${h.blastProgram} (${h.msaAlgorithm})`,secondary:`${new Date(h.timestamp).toLocaleString()} - Seq: ${h.proteinSequence.slice(0,30)}...`}))))))}),pP=J7;var fx=p(Q()),xP=p(U());var FA="https://blast.ncbi.nlm.nih.gov/Blast.cgi",gP=["clustalo","muscle","kalign","mafft"],hP=["nr","nr_cluster_seq"],yP=["blastp","quick-blastp"];function Yi({value:e,onChange:t,className:r}){return fx.default.createElement(ct,{variant:"outlined",label:"MSA Algorithm",className:r,select:!0,value:e,onChange:n=>{t(n.target.value)}},gP.map(n=>fx.default.createElement(xP.MenuItem,{value:n,key:n},n)))}var K7=(0,bP.makeStyles)()({selectField:{width:150},databaseFieldContainer:{display:"flex"},clusterSeqMessage:{marginLeft:4,alignContent:"center"},cachedResultsAccordion:{marginTop:20},infoText:{marginTop:20}}),X7=(0,CP.observer)(function({handleClose:e,feature:t,model:r,children:n,baseUrl:o}){let{classes:i}=K7(),s=tr(r),[a,c]=(0,Ee.useState)(),[l,u]=(0,Ee.useState)("nr"),[d,A]=(0,Ee.useState)("clustalo"),[f,g]=(0,Ee.useState)("quick-blastp"),h=(0,Ee.useMemo)(()=>Qa(t),[t]),{results:y,error:E}=PA(h),x=Nr({feature:t,view:s}),{selectedTranscript:S,proteinSequence:w}=x,I=x.error??a??E;return Ee.default.createElement(Ee.default.Fragment,null,Ee.default.createElement(pr,{error:I},n,Ee.default.createElement(ct,{variant:"outlined",label:"BLAST database",className:i.selectField,select:!0,value:l,onChange:v=>{let B=v.target.value;u(B),B==="nr_cluster_seq"&&g("blastp")}},hP.map(v=>Ee.default.createElement(yr.MenuItem,{value:v,key:v},v))),Ee.default.createElement(Yi,{className:i.selectField,value:d,onChange:A}),Ee.default.createElement("div",{className:i.databaseFieldContainer},Ee.default.createElement(ct,{variant:"outlined",label:"BLAST program",disabled:l==="nr_cluster_seq",className:i.selectField,select:!0,value:f,onChange:v=>{g(v.target.value)}},yP.map(v=>Ee.default.createElement(yr.MenuItem,{value:v,key:v},v))),l==="nr_cluster_seq"?Ee.default.createElement(yr.Typography,{variant:"subtitle2",className:i.clusterSeqMessage},"Can only use blastp on nr_cluster_seq"):null),Ee.default.createElement(gr,{feature:t,...x}),Ee.default.createElement(yr.Typography,{className:i.infoText},"This panel will automatically submit a query to NCBI. Using blastp can take 10+ minutes to run, quick-blastp is generally a lot faster but is not available for the clustered database. After completion, all the hits will be run through a multiple sequence alignment. Note: we are not able to currently run NCBI COBALT automatically on the BLAST results, even though that is the method NCBI uses on their website. If you need a COBALT alignment, please use the manual approach of submitting BLAST yourself and downloading the resulting files"),y.length>0?Ee.default.createElement(yr.Accordion,{className:i.cachedResultsAccordion},Ee.default.createElement(yr.AccordionSummary,{expandIcon:Ee.default.createElement(Vd,null)},Ee.default.createElement(yr.Typography,null,"Previous BLAST Results")),Ee.default.createElement(yr.AccordionDetails,null,Ee.default.createElement(pP,{model:r,handleClose:e,feature:t}))):null),Ee.default.createElement(rn,{submitDisabled:!w,onSubmit:()=>{try{S&&(c(void 0),LA({feature:S,view:s,newViewTitle:lA(t,S),blastParams:{baseUrl:o,blastProgram:f,blastDatabase:l,msaAlgorithm:d,selectedTranscript:S,proteinSequence:w}}),e())}catch(v){console.error(v),c(v)}},onCancel:e}))}),EP=X7;var Ln=p(Q()),BP=p(we()),Ga=p(U()),TP=p(W()),MP=p(Tt());OA();var Z7=(0,MP.makeStyles)()({ncbiLink:{wordBreak:"break-all",margin:30,maxWidth:600},infoText:{marginTop:20}}),e$=(0,TP.observer)(function({handleClose:e,feature:t,model:r,children:n,baseUrl:o}){let{classes:i}=Z7(),s=tr(r),a=Nr({feature:t,view:s}),{proteinSequence:c,error:l}=a,u=Ra(c),d=`${o}?PAGE_TYPE=BlastSearch&PAGE=Proteins&PROGRAM=blastp&QUERY=${u}`,A=`${o}?PAGE_TYPE=BlastSearch&PAGE=Proteins&PROGRAM=blastp&QUERY=${(0,BP.shorten2)(u,10)}`;return Ln.default.createElement(Ln.default.Fragment,null,Ln.default.createElement(pr,{error:l},n,Ln.default.createElement(gr,{feature:t,...a}),c?Ln.default.createElement("div",{className:i.ncbiLink},"Link to NCBI BLAST: ",Ln.default.createElement(qi,{href:d},A)):null,Ln.default.createElement(Ga.Typography,{className:i.infoText},`Click the link above and run your BLAST query, and once you have results, click "Multiple Alignment" at the top of the results page to be redirected to COBALT, NCBI's multiple sequence aligner. Once COBALT completes, you can download an MSA (.aln file) and optionally a Newick tree (.nh) and paste the results into JBrowse`)),Ln.default.createElement(Ga.DialogActions,null,Ln.default.createElement(Ga.Button,{color:"primary",variant:"contained",onClick:()=>{e()}},"Close")))}),RP=e$;var so=p(Q()),Pr=p(U());function Ax({lookupMethod:e,setLookupMethod:t}){return so.default.createElement(Pr.FormControl,{component:"fieldset"},so.default.createElement(Pr.RadioGroup,{row:!0,value:e,onChange:r=>{t(r.target.value)}},so.default.createElement(Pr.FormControlLabel,{value:"automatic",control:so.default.createElement(Pr.Radio,null),label:"Automatic"}),so.default.createElement(Pr.FormControlLabel,{value:"rid",control:so.default.createElement(Pr.Radio,null),label:"Load from RID"}),so.default.createElement(Pr.FormControlLabel,{value:"manual",control:so.default.createElement(Pr.Radio,null),label:"Manual"})))}var Nt=p(Q()),GA=p(U()),QP=p(W()),_P=p(Tt());OA();var t$=(0,_P.makeStyles)()({marginBottom:{marginBottom:16},ridField:{width:150},infoText:{marginTop:20}}),r$=(0,QP.observer)(function({handleClose:e,feature:t,model:r,children:n,baseUrl:o}){let{classes:i}=t$(),s=tr(r),[a,c]=(0,Nt.useState)(),[l,u]=(0,Nt.useState)(""),[d,A]=(0,Nt.useState)("clustalo"),f=Nr({feature:t,view:s}),{selectedTranscript:g,proteinSequence:h}=f,y=f.error??a,E=l.trim();return Nt.default.createElement(Nt.default.Fragment,null,Nt.default.createElement(pr,{error:y},n,Nt.default.createElement(GA.Typography,{variant:"body2",className:i.marginBottom},"Enter the RID (Request ID) from a previously submitted NCBI BLAST query. You can find the RID in the BLAST results page URL or at the top of the results page. RIDs are typically valid for 24-36 hours after submission."),Nt.default.createElement(ct,{variant:"outlined",label:"BLAST RID",placeholder:"e.g., ABC12345",fullWidth:!0,className:i.marginBottom,value:l,onChange:x=>{u(x.target.value)}}),E?Nt.default.createElement(GA.Typography,{variant:"body2",className:i.marginBottom},Nt.default.createElement(qi,{href:`${o}?CMD=Get&RID=${E}`},"View BLAST results on NCBI")):null,Nt.default.createElement(Yi,{className:i.ridField,value:d,onChange:A}),Nt.default.createElement(gr,{feature:t,...f}),Nt.default.createElement(GA.Typography,{className:i.infoText},"This will fetch the BLAST results for the provided RID and run them through a multiple sequence alignment. The protein sequence from the selected transcript will be added as the query sequence in the MSA.")),Nt.default.createElement(rn,{submitDisabled:!h||!E,onSubmit:()=>{try{g&&E&&(c(void 0),LA({feature:g,view:s,newViewTitle:lA(t,g),blastParams:{baseUrl:o,blastProgram:"blastp",blastDatabase:"nr",msaAlgorithm:d,selectedTranscript:g,proteinSequence:h,rid:E}}),e())}catch(x){console.error(x),c(x)}},onCancel:e}))}),kP=r$;var cn=p(Q()),Fr=p(U()),DP=p(Tt());var n$=(0,DP.makeStyles)()({urlField:{minWidth:300}});function mx({handleClose:e,baseUrl:t}){let{classes:r}=n$(),[n,o]=(0,cn.useState)(t);return cn.default.createElement(Fr.Dialog,{open:!0,maxWidth:"lg",onClose:()=>{e()}},cn.default.createElement(Fr.DialogTitle,null,"BLAST Settings"),cn.default.createElement(Fr.DialogContent,null,cn.default.createElement(ct,{autoFocus:!0,margin:"dense",label:"BLAST Base URL",fullWidth:!0,variant:"outlined",value:n,className:r.urlField,onChange:i=>{o(i.target.value)}}),cn.default.createElement(Fr.Button,{variant:"contained",onClick:()=>{o(FA)}},"Reset")),cn.default.createElement(Fr.DialogActions,null,cn.default.createElement(Fr.Button,{variant:"contained",color:"secondary",onClick:()=>{e()}},"Cancel"),cn.default.createElement(Fr.Button,{color:"primary",variant:"contained",onClick:()=>{e(n)}},"Save")))}var NP=p(Q());function o$(e,t){try{let r=globalThis.localStorage.getItem(e);return r===null?t:JSON.parse(r)}catch(r){return console.error(r),t}}function LP(e,t){let[r,n]=(0,NP.useState)(()=>o$(e,t));return[r,i=>{n(i);try{globalThis.localStorage.setItem(e,JSON.stringify(i))}catch(s){console.error(s)}}]}var i$=(0,FP.makeStyles)()({settingsButton:{float:"right"}}),s$={automatic:EP,rid:kP,manual:RP};function px({handleClose:e,model:t,feature:r}){let[n,o]=(0,ln.useState)("automatic"),[i,s]=LP("msa-blastRootUrl",FA),[a,c]=(0,ln.useState)(!1),{classes:l}=i$(),u=s$[n];return ln.default.createElement(ln.default.Fragment,null,ln.default.createElement(PP.IconButton,{className:l.settingsButton,size:"small",onClick:()=>{c(!0)}},ln.default.createElement(aP,null)),ln.default.createElement(u,{model:t,feature:r,handleClose:e,baseUrl:i},ln.default.createElement(Ax,{lookupMethod:n,setLookupMethod:o})),a?ln.default.createElement(mx,{baseUrl:i,handleClose:d=>{d&&s(d),c(!1)}}):null)}var $e=p(Q()),ao=p(U()),UP=p(W()),HP=p(Tt());var OP=p(we());function GP({newViewTitle:e,view:t,feature:r,orthologParams:n}){(0,OP.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,connectedViewId:t.id,connectedFeature:r.toJSON(),drawNodeBubbles:!0,colWidth:10,rowHeight:12,orthologParams:n})}var a$=(0,HP.makeStyles)()({selectField:{width:180},speciesBox:{display:"grid",gridTemplateColumns:"repeat(auto-fit, minmax(130px, 1fr))",maxWidth:700,marginTop:4},species:{marginRight:0}}),c$=(0,UP.observer)(function({handleClose:e,feature:t,model:r}){let{classes:n}=a$(),o=tr(r),[i,s]=(0,$e.useState)(),[a,c]=(0,$e.useState)(9606),[l,u]=(0,$e.useState)("clustalo"),[d,A]=(0,$e.useState)([]),f=(0,$e.useMemo)(()=>Qa(t),[t]),g=Nr({feature:t,view:o}),{selectedTranscript:h,proteinSequence:y}=g,E=g.error??i,x=ji.map(S=>S.taxId).filter(S=>!d.includes(S));return $e.default.createElement($e.default.Fragment,null,$e.default.createElement(pr,{error:E},$e.default.createElement(ao.Typography,{variant:"body2"},"NCBI's precomputed orthologs, one gene per species, aligned at EBI in seconds rather than the 10+ minutes BLAST takes."),$e.default.createElement("div",null,$e.default.createElement(ct,{variant:"outlined",label:"Query species",className:n.selectField,select:!0,value:a,onChange:S=>{c(Number(S.target.value))},helperText:"the species this gene is from"},ji.map(S=>$e.default.createElement(ao.MenuItem,{value:S.taxId,key:S.taxId},S.label))),$e.default.createElement(Yi,{className:n.selectField,value:l,onChange:u})),$e.default.createElement(ao.Typography,{variant:"subtitle2",style:{marginTop:8}},"Species to include (those without an ortholog are skipped)"),$e.default.createElement("div",{className:n.speciesBox},ji.map(S=>$e.default.createElement(ao.FormControlLabel,{className:n.species,key:S.taxId,control:$e.default.createElement(ao.Checkbox,{checked:!d.includes(S.taxId),onChange:w=>{A(w.target.checked?d.filter(I=>I!==S.taxId):[...d,S.taxId])}}),label:S.label}))),$e.default.createElement(gr,{feature:t,...g})),$e.default.createElement(rn,{submitDisabled:!y||x.length<2,onSubmit:()=>{try{h&&(s(void 0),GP({feature:h,view:o,newViewTitle:`Orthologs - ${io(t)} - ${Ma(h)}`,orthologParams:{taxId:a,taxa:x,geneCandidates:f,msaAlgorithm:l,selectedTranscript:h,proteinSequence:y}}),e())}catch(S){console.error(S),s(S)}},onCancel:e}))}),VP=c$;var Lt=p(Q()),Pl=p(Ze()),HA=p(we()),XP=p(U()),ZP=p(W());var eF=p(Tt());So();function gx(e,t="",r=5e3){let n=[e];for(;n.length;){let o=n.pop();for(let[i,s]of Object.entries(o)){if(t.length>r)return jh(t);typeof s=="object"&&s!==null?n.push(s):i==="locationType"&&s==="FileHandleLocation"?t+=`${i}-BlobLocation`:i==="handleId"?t+=`blobId-fh-blob-${s}`:t+=`${i}-${s}`}}return`adp-${jh(t)}`}function jP(e={}){return e.type&&e.adapterId?`${e.type}-${e.adapterId}`:`${gx(e)}`}var $P={};async function l$(e,t,r){let n=r?.type;if(!n)throw new Error(`could not determine adapter type from adapter config snapshot ${JSON.stringify(r)}`);let o=e.getAdapterType(n);if(!o)throw new Error(`unknown data adapter type ${n}`);let i=o.configSchema.create(r,{pluginManager:e}),s=hx.bind(null,e,t),a=await o.getAdapterClass();return{dataAdapter:new a(i,s,e),sessionIds:new Set([t])}}async function hx(e,t,r){let n=jP(r);$P[n]??=l$(e,t,r);let o=await $P[n];return o.sessionIds.add(t),o}async function WP(e,t){return(await hx(e,"msa",t)).dataAdapter}async function YP({config:e,pluginManager:t}){return(await WP(t,e)).getMSAList()}async function qP({config:e,pluginManager:t,msaId:r}){return(await WP(t,e)).getMSA(r)}var zP=p(we());function JP({newViewTitle:e,view:t,feature:r,data:n,querySeqName:o}){(0,zP.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,treeAreaWidth:200,querySeqName:o,treeWidth:100,drawNodeBubbles:!1,labelsAlignRight:!0,showBranchLen:!1,colWidth:10,rowHeight:12,colorSchemeName:"percent_identity_dynamic",data:n,connectedViewId:t.id,connectedFeature:r.toJSON()})}var KP=p(as());function UA(e){return(0,KP.readConfObject)(e,["msa","datasets"])}var u$=(0,eF.makeStyles)()({selectedContainer:{marginTop:50}}),f$=(0,ZP.observer)(function({model:e,feature:t,handleClose:r}){let n=(0,HA.getSession)(e),o=tr(e),{classes:i}=u$(),{pluginManager:s}=(0,HA.getEnv)(e),{assemblyNames:a}=o,[c,l]=(0,Lt.useState)(),u=UA(n.jbrowse),[d,A]=(0,Lt.useState)(u?.[0]?.datasetId),f=u?.find(R=>R.datasetId===d),{data:g,isLoading:h,error:y}=$i(f?`${f.datasetId}-msa-list`:null,()=>YP({config:f.adapter,pluginManager:s}),Wi),E=Nr({feature:t,view:o,validIds:g}),{selectedId:x,selectedTranscript:S}=E,{data:w,isLoading:I,error:v}=$i(x&&f&&g?`${f.datasetId}-${x}-msa`:null,()=>qP({msaId:x,config:f.adapter,pluginManager:s}),Wi),B=y??v??E.error??c;return Lt.default.createElement(Lt.default.Fragment,null,Lt.default.createElement(pr,{error:B},Lt.default.createElement(ct,{select:!0,label:"Select MSA dataset",value:d,onChange:R=>{A(R.target.value)}},u?.map(R=>Lt.default.createElement(XP.MenuItem,{key:R.datasetId,value:R.datasetId},R.name))),f?Lt.default.createElement("div",{className:i.selectedContainer},!h&&I?Lt.default.createElement(Pl.LoadingEllipses,{variant:"h6",message:`Loading MSA for (${x})`}):null,h?Lt.default.createElement(Pl.LoadingEllipses,{variant:"h6",message:`Loading available MSAs for (${f.name})`}):null,g?Lt.default.createElement("div",null,Lt.default.createElement(Pl.SanitizedHTML,{html:f.description}),Lt.default.createElement(gr,{feature:t,...E})):null):null),Lt.default.createElement(rn,{submitDisabled:!S||!w?.length,onSubmit:()=>{try{if(S&&w){let R=`${x}_${a[0]}`;JP({newViewTitle:io(S),view:o,querySeqName:R,feature:S,data:{msa:w.map(D=>`>${D.get("refName")}
+`),onProgress:a}),treeMetadata:JSON.stringify(f)}}async function d7(e,t){let r;try{let n=(await Na([e])).get(e);r=n?.commonName??n?.sciname}catch(n){console.warn("[msaview-orthologs] taxonomy name lookup failed:",n)}return $y([...t.map(n=>n.label),`${r??"query"}_query`]).at(-1)}async function A7(e){try{return await HN(e)}catch(t){console.warn("[msaview-orthologs] query protein lookup failed:",t);return}}function m7(e,t,r,n){let o=e.orthologParams?.selectedTranscript,i={"Gene ID":t},s=o?.get("name")??o?.get("id");return s&&(i.Transcript=s),n?.sequence===r&&(i.Accession=n.accession),i}function p7(e){let t={"Scientific name":e.scientificName,Accession:e.protein,"Gene ID":e.geneId};return e.commonName&&(t["Common name"]=e.commonName),t}Ch();var WN=p(Ey());async function YN({location:e,name:t}){let r=i=>(0,WN.openLocation)({uri:i,locationType:"UriLocation"}),n=await r(`${e.uri}.idx`).readFile("utf8"),o=g7(n,t);if(o){let s=await new oa({filehandle:r(e.uri),gziFilehandle:r(`${e.uri}.gzi`)}).read(o.length,o.offset);return new TextDecoder().decode(s).trim()}}var $N=e=>e.replace(/\.\d+$/,"");function g7(e,t){let r=$N(t);for(let n of e.split(`
+`)){let[o,i,s]=n.split("	");if(o&&$N(o)===r)return{offset:Number(i),length:Number(s)}}}var qN=p(be());function zN({model:e}){let{hovered:t}=(0,qN.getSession)(e),{querySeqName:r,transcriptToMsaMap:n,connectedView:o,mafRegion:i}=e;if(!o?.initialized||!ci(t))return;let{coord:s,refName:a}=t.hoverPosition,c=s-1;if(i)return a!==i.refName||!o.assemblyNames.includes(i.assemblyName)||c<i.start||c>=i.end?void 0:e.seqPosToVisibleCol(r,c-i.start);if(a===n?.refName){let l=n.g2p[c];if(l!==void 0)return e.seqPosToVisibleCol(r,l)}}var h7="jbrowse-msaview-domain-cache",BA="domains",y7=1,JN=Ho(h7,y7,e=>{e.objectStoreNames.contains(BA)||e.createObjectStore(BA,{keyPath:"accession"})});async function KN(e){let r=(await JN()).transaction(BA,"readonly"),n=await Promise.all(e.map(o=>r.store.get(o)));return await r.done,n}async function XN(e){let r=(await JN()).transaction(BA,"readwrite");for(let n of e)await r.store.put(n);await r.done}ji();function Vo(e,t){return new RegExp(`<${t}>(.*?)</${t}>`,"s").exec(e)?.[1]}function x7(e){let t={},r=/<GBQualifier>([\s\S]*?)<\/GBQualifier>/g,n;for(;(n=r.exec(e))!==null;){let o=Vo(n[1],"GBQualifier_name"),i=Vo(n[1],"GBQualifier_value");o&&i!==void 0&&t[o]===void 0&&(t[o]=i)}return t}function C7(e){let t=[],r=[],n=/<GBInterval>([\s\S]*?)<\/GBInterval>/g,o;for(;(o=n.exec(e))!==null;){let i=o[1],s=Vo(i,"GBInterval_from"),a=Vo(i,"GBInterval_to"),c=Vo(i,"GBInterval_point");s&&a?(t.push(Number(s)),r.push(Number(a))):c&&(t.push(Number(c)),r.push(Number(c)))}return t.length>0?{start:Math.min(...t),end:Math.max(...r)}:void 0}var E7=2;function b7(e){let t=Vo(e,"GBFeature_key"),r=x7(e),n=r.db_xref,o=C7(e);if((t==="Region"||t==="Site")&&n?.startsWith("CDD:")&&o&&o.end-o.start+1>=E7){let i=n.replace("CDD:",""),s=t==="Region",a=r.note?.split(/[[(]/)[0]?.trim(),c=s?r.region_name??i:a||r.site_type||"site",l=s?i:`${i}:${c}`;return{signature:{entry:{name:c,description:r.note??c,accession:l}},locations:[o]}}}function w7(e){let t=new Map,r=/<GBSeq>([\s\S]*?)<\/GBSeq>/g,n;for(;(n=r.exec(e))!==null;){let o=n[1],i=[],s=/<GBFeature>([\s\S]*?)<\/GBFeature>/g,a;for(;(a=s.exec(o))!==null;){let c=b7(a[1]);c&&i.push(c)}for(let c of[Vo(o,"GBSeq_accession-version"),Vo(o,"GBSeq_primary-accession")])c&&t.set(c,i)}return t}async function ZN(e){let t=[...new Set(e)].filter(Boolean),r=new Map,n=await KN(t),o=[];t.forEach((a,c)=>{let l=n[c];l?r.set(a,l.matches):o.push(a)});let i=[],s=100;for(let a=0;a<o.length;a+=s){let c=o.slice(a,a+s),l=await qr(SA({db:"protein",id:c.join(","),rettype:"gp",retmode:"xml"})),u=w7(l);for(let d of c){let A=u.get(d);A!==void 0&&(r.set(d,A),i.push({accession:d,matches:A}))}}return i.length>0&&await XN(i),r}async function eL(e){let t=e.data.treeMetadata;if(!t)throw new Error("No sequence metadata available to look up domains");let r=JSON.parse(t),n=Object.entries(r).map(([s,a])=>({rowName:s,accession:a.Accession})).filter(s=>!!s.accession);if(n.length===0)throw new Error("No NCBI accessions found in alignment rows");e.setProgress(`Fetching protein domains from NCBI for ${n.length} sequences...`);let o=await ZN(n.map(s=>s.accession)),i={};for(let{rowName:s,accession:a}of n){let c=o.get(a);c&&c.length>0&&(i[s]={matches:c,xref:[{id:s}]})}if(Object.keys(i).length===0)throw new Error("No CDD domain annotations found for these proteins");e.setDomains(i)}var I7="jbrowse-msaview-data",S7=1,Ll="msa-data",Wy=Ho(I7,S7,e=>{e.objectStoreNames.contains(Ll)||e.createObjectStore(Ll,{keyPath:"id"}).createIndex("timestamp","timestamp",{unique:!1})});function tL(){return`msa-${Date.now()}-${Math.random().toString(36).slice(2,11)}`}async function rL(e,t){try{let r=await Wy(),n={id:e,msa:t.msa,tree:t.tree,treeMetadata:t.treeMetadata,timestamp:Date.now()};return await r.put(Ll,n),!0}catch(r){return console.warn("Failed to store MSA data:",r),!1}}async function nL(e){try{let r=await(await Wy()).get(Ll,e);return r?{msa:r.msa,tree:r.tree,treeMetadata:r.treeMetadata}:void 0}catch(t){console.warn("Failed to retrieve MSA data:",t);return}}async function oL(e=10080*60*1e3){try{let t=await Wy(),r=Date.now()-e,i=await t.transaction(Ll,"readwrite").store.index("timestamp").openCursor(IDBKeyRange.upperBound(r)),s=0;for(;i;)await i.delete(),s++,i=await i.continue();return s}catch(t){return console.warn("Failed to cleanup old MSA data:",t),0}}function v7(e){let t=e;return t.type==="ProteinView"&&Array.isArray(t.structures)}function iL(e){return e.filter(v7)}function sL(e,t){if(t<0||t>=e.length)return;let r=0;for(let n=0;n<t;n++)e[n]!=="-"&&r++;if(e[t]!=="-")return r}function cL(e){let{dataStoreId:t,rows:r}=e;t&&r.length===0&&(async()=>{try{e.setLoadingStoredData(!0);let n=await nL(t);n&&(n.msa&&e.setMSA(n.msa),n.tree&&e.setTree(n.tree),n.treeMetadata&&e.setTreeMetadata(n.treeMetadata))}catch(n){console.error("Failed to load MSA data from IndexedDB:",n)}finally{e.setLoadingStoredData(!1)}})()}function lL(e){let{rows:t,dataStoreId:r,isStoringData:n}=e;if(t.length>0&&!r&&!n){if(e.msaFilehandle||e.treeFilehandle)return;let o=e.data.msa,i=e.data.tree;(o||i)&&(e.setIsStoringData(!0),(async()=>{try{let s=tL();await rL(s,{msa:o,tree:i,treeMetadata:e.data.treeMetadata})&&e.setDataStoreId(s)}catch(s){console.error("Failed to store MSA data to IndexedDB:",s)}finally{e.setIsStoringData(!1)}})())}}function uL(e){e.orthologParams&&(async()=>{try{e.setProgress("Resolving orthologs"),e.setError(void 0);let t=await jN({self:e});e.setData(t),e.setOrthologParams(void 0)}catch(t){e.setError(t),console.error(t)}finally{e.setProgress("")}})()}function fL(e){e.blastParams&&(async()=>{try{e.setProgress("Submitting query"),e.setError(void 0);let t=await NN({self:e});e.setData(t),e.setBlastParams(void 0)}catch(t){e.setError(t),console.error(t)}finally{e.setProgress("")}})()}function dL(e){let{rows:t,domainsRequested:r,interProAnnotations:n}=e,o=e.data.treeMetadata?.includes('"Accession"')??!1;t.length>0&&o&&!n&&!r&&(e.setDomainsRequested(!0),(async()=>{try{await eL(e)}catch(i){console.error("[msaview-domains] auto-load failed:",i)}finally{e.setProgress("")}})())}function AL(e){let{init:t}=e;if(t){let{msaUrl:r,msaIndexedLocation:n,msaName:o,querySeqName:i}=t;(async()=>{try{if(e.setError(void 0),r){let s=Kw(r);s&&(e.setUniprotId(s),e.setQuerySeqName("query"))}if(i&&e.setQuerySeqName(i),r)e.setMSAFilehandle({uri:r,locationType:"UriLocation"});else if(n&&o){let s=await YN({location:n,name:o});if(s)e.setMSA(s);else throw new Error(`No alignment named ${o} in ${n.uri}`)}e.setInit(void 0)}catch(s){e.setError(s),console.error(s)}})()}}function mL(e){let t=!1;return()=>{let r=zN({model:e});r!==void 0?(e.setMousePos(r),t=!0):t&&(e.setMousePos(void 0),t=!1)}}function pL(e){let t=!1;return()=>{let{connectedViewId:r,transcriptToMsaMap:n,querySeqName:o}=e;if(!r||!n)return;let i=new Set;for(let a of iL((0,aL.getSession)(e).views))for(let c of a.structures){if(c.connectedViewId!==r)continue;let l=c.hoverGenomeHighlights;if(!l||l.length===0)continue;let{g2p:u}=n;for(let d of l)for(let A=d.start;A<d.end;A++){let f=u[A];if(f!==void 0){let g=e.seqPosToGlobalCol(o,f);i.add(g)}}}let s=Array.from(i).map(a=>e.globalColToVisibleCol(a)).filter(a=>a!==void 0);s.length>0?(e.setHighlightedColumns(s),t=!0):t&&(e.setHighlightedColumns(e.highlightColumns?.length?e.highlightColumns:void 0),t=!1)}}function gL(){oL().catch(e=>{console.error("Failed to cleanup old MSA data:",e)})}function TA({model:e,coord:t}){let{querySeqName:r,transcriptToMsaMap:n,mafRegion:o,rows:i}=e,s=i.find(c=>c[0]===r)?.[1];if(!s)return[];let a=sL(s,t);if(a===void 0)return[];if(o){let c=o.start+a;return c<o.end?[{refName:o.refName,start:c,end:c+1}]:[]}if(n){let{refName:c,p2gCodon:l}=n;return tI(l,a)?.map(([u,d])=>({refName:c,start:u,end:d}))??[]}return[]}function hL(e){let t=TA(e),r=t[0],n=t.at(-1);return r&&n?{refName:r.refName,start:r.start,end:n.end}:void 0}function Yy(){return mt.types.compose(yL.BaseViewModel,hA(),mt.types.model("MsaView",{connectedViewId:mt.types.maybe(mt.types.string),connectedFeature:mt.types.frozen(),blastParams:mt.types.frozen(),orthologParams:mt.types.frozen(),querySeqName:"QUERY",uniprotId:mt.types.maybe(mt.types.string),zoomToBaseLevel:!1,init:mt.types.frozen(),dataStoreId:mt.types.maybe(mt.types.string),mafRegion:mt.types.frozen()})).volatile(()=>({rid:void 0,progress:"",error:void 0,loadingStoredData:!1,isStoringData:!1,domainsRequested:!1})).views(e=>({getRowByName(t){return e.rows.find(r=>r[0]===t)},getSequenceByRowName(t){return e.rows.find(r=>r[0]===t)?.[1]}})).views(e=>({get transcriptToMsaMap(){return e.connectedFeature?eI(e.connectedFeature):void 0},get connectedView(){let{views:t}=(0,xL.getSession)(e);return t.find(r=>r.id===e.connectedViewId)}})).views(e=>({get connectedHoverHighlights(){let{mouseCol:t}=e;return t===void 0?[]:TA({model:e,coord:t})},get connectedClickHighlights(){let{mouseClickCol:t}=e;return t===void 0?[]:TA({model:e,coord:t})},get connectedHighlights(){return[...this.connectedHoverHighlights,...this.connectedClickHighlights]}})).actions(e=>({setZoomToBaseLevel(t){e.zoomToBaseLevel=t},setError(t){e.error=t},setProgress(t){e.progress=t},setRid(t){e.rid=t},setBlastParams(t){e.blastParams=t},setOrthologParams(t){e.orthologParams=t},setInit(t){e.init=t},setQuerySeqName(t){e.querySeqName=t},setUniprotId(t){e.uniprotId=t},setDataStoreId(t){e.dataStoreId=t},setMafRegion(t){e.mafRegion=t},setLoadingStoredData(t){e.loadingStoredData=t},setIsStoringData(t){e.isStoringData=t},setDomainsRequested(t){e.domainsRequested=t},handleMsaClick(t){let{connectedView:r,zoomToBaseLevel:n}=e,o=hL({model:e,coord:t});!o||!r||(n?r.navTo(o):r.centerAt(o.start,o.refName))}})).actions(e=>{let t=e.setMouseClickPos.bind(e);return{setMouseClickPos(r,n){t(r,n),r!==void 0&&e.handleMsaClick(r)}}}).views(e=>({extraViewMenuItems(){return[{label:"Zoom to base level on click?",checked:e.zoomToBaseLevel,type:"checkbox",onClick:()=>{e.setZoomToBaseLevel(!e.zoomToBaseLevel)}}]}})).actions(e=>({afterCreate(){gL();for(let t of[cL,lL,fL,uL,AL,dL])(0,mt.addDisposer)(e,(0,MA.autorun)(()=>{t(e)}));(0,mt.addDisposer)(e,(0,MA.autorun)(mL(e))),(0,mt.addDisposer)(e,(0,MA.autorun)(pL(e)))}}))}function La(e){return e.type==="MsaView"}var B7=(0,zy.observer)(function({model:e}){let{hovered:t,views:r}=(0,CL.getSession)(e);return r.some(o=>La(o)&&o.connectedViewId===e.id)&&ci(t)?qy.default.createElement(T7,{model:e,hovered:t}):null}),T7=(0,zy.observer)(function({model:e,hovered:t}){let{classes:r}=af(),{offsetPx:n}=e,{coord:o,refName:i}=t.hoverPosition,s=e.bpToPx({refName:i,coord:o-1}),a=e.bpToPx({refName:i,coord:o});if(s&&a){let c=Math.max(Math.abs(a.offsetPx-s.offsetPx),4),l=Math.min(s.offsetPx,a.offsetPx)-n;return qy.default.createElement("div",{className:r.highlight,style:{left:l,width:c}})}return null}),EL=B7;var Fl=p(Q()),bL=p(be()),Jy=p(Y());var M7=(0,Jy.observer)(function({model:t}){let{views:r,hovered:n}=(0,bL.getSession)(t),o=r.filter(La).find(s=>s.connectedViewId===t.id),i=[...o?.connectedClickHighlights??[],...ci(n)?[]:o?.connectedHoverHighlights??[]];return i.length?Fl.default.createElement(R7,{model:t,highlights:i}):null}),R7=(0,Jy.observer)(function({model:e,highlights:t}){let{classes:r}=af(),{offsetPx:n}=e;return Fl.default.createElement(Fl.default.Fragment,null,t.map((o,i)=>{let s=e.bpToPx({refName:o.refName,coord:o.start}),a=e.bpToPx({refName:o.refName,coord:o.end});if(s&&a){let c=Math.max(Math.abs(a.offsetPx-s.offsetPx),4),l=Math.min(s.offsetPx,a.offsetPx)-n;return Fl.default.createElement("div",{key:`${o.refName}-${o.start}-${o.end}-${i}`,className:r.highlight,style:{left:l,width:c}})}return null}))}),wL=M7;var Q7=(0,IL.observer)(function({model:t}){return Pl.default.createElement(Pl.default.Fragment,null,Pl.default.createElement(wL,{model:t}),Pl.default.createElement(EL,{model:t}))}),SL=Q7;function Ky(e){e.addToExtensionPoint("LinearGenomeView-TracksContainerComponent",(t,{model:r})=>{let{views:n}=(0,BL.getSession)(r);return n.some(i=>La(i)&&i.connectedViewId===r.id)?[...t,vL.default.createElement(SL,{key:"highlight_protein_viewer_msaview",model:r})]:t})}var NL=p(jp());var TL=p(ss());function Xy(e){let t=e.getAdapterType("BgzipFastaAdapter");return(0,TL.ConfigurationSchema)("BgzipFastaMsaAdapter",{msaRegex:{type:"string",defaultValue:"_"}},{baseConfiguration:t?.configSchema})}function Zy(e){return e.addAdapterType(()=>new NL.AdapterType({name:"BgzipFastaMsaAdapter",configSchema:Xy(e),adapterMetadata:{hiddenFromGUI:!0},getAdapterClass:()=>Promise.resolve().then(()=>(DL(),kL)).then(t=>t.default)}))}var JA=p(be());we();var LL=p(O(),1),FL=W((0,LL.jsx)("path",{d:"M19 13h-6v6h-2v-6H5v-2h6V5h2v6h6z"}),"Add");var wt=p(Q()),CP=p(Xe()),EP=p(be()),qi=p(U());var rn=p(Q());we();var PL=p(O(),1),OL=W((0,PL.jsx)("path",{d:"M19.14 12.94c.04-.3.06-.61.06-.94 0-.32-.02-.64-.07-.94l2.03-1.58c.18-.14.23-.41.12-.61l-1.92-3.32c-.12-.22-.37-.29-.59-.22l-2.39.96c-.5-.38-1.03-.7-1.62-.94l-.36-2.54c-.04-.24-.24-.41-.48-.41h-3.84c-.24 0-.43.17-.47.41l-.36 2.54c-.59.24-1.13.57-1.62.94l-2.39-.96c-.22-.08-.47 0-.59.22L2.74 8.87c-.12.21-.08.47.12.61l2.03 1.58c-.05.3-.09.63-.09.94s.02.64.07.94l-2.03 1.58c-.18.14-.23.41-.12.61l1.92 3.32c.12.22.37.29.59.22l2.39-.96c.5.38 1.03.7 1.62.94l.36 2.54c.05.24.24.41.48.41h3.84c.24 0 .44-.17.47-.41l.36-2.54c.59-.24 1.13-.56 1.62-.94l2.39.96c.22.08.47 0 .59-.22l1.92-3.32c.12-.22.07-.47-.12-.61zM12 15.6c-1.98 0-3.6-1.62-3.6-3.6s1.62-3.6 3.6-3.6 3.6 1.62 3.6 3.6-1.62 3.6-3.6 3.6"}),"Settings");var YF=p(U()),qF=p(Ut());var je=p(Q());dy();var tn=p(U()),NF=p(Y()),LF=p(Ut());var pt=p(Q()),uF=p(Xe());we();var GL=p(O(),1),UL=W((0,GL.jsx)("path",{d:"M6 19c0 1.1.9 2 2 2h8c1.1 0 2-.9 2-2V7H6zM19 4h-3.5l-1-1h-5l-1 1H5v2h14z"}),"Delete");var kt=p(U()),fF=p(Y()),dF=p(Ut());var ex=p(be());function HL({newViewTitle:e,view:t,feature:r,blastParams:n}){(0,ex.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,connectedViewId:t.id,connectedFeature:r.toJSON(),drawNodeBubbles:!0,colWidth:10,rowHeight:12,blastParams:n})}function VL({newViewTitle:e,view:t,cached:r,connectedFeature:n}){(0,ex.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,connectedViewId:t.id,connectedFeature:n,drawNodeBubbles:!0,colWidth:10,rowHeight:12,data:{msa:r.msa,tree:r.tree,treeMetadata:r.treeMetadata}})}var at=p(Q(),1),gx=p(YL(),1);var bt=p(Q(),1);var jo={};Bt(jo,{ERROR_REVALIDATE_EVENT:()=>U7,FOCUS_EVENT:()=>qL,MUTATE_EVENT:()=>JL,RECONNECT_EVENT:()=>zL});var qL=0,zL=1,JL=2,U7=3;var KL=Object.prototype.hasOwnProperty;function QA(e,t){var r,n;if(e===t)return!0;if(e&&t&&(r=e.constructor)===t.constructor){if(r===Date)return e.getTime()===t.getTime();if(r===RegExp)return e.toString()===t.toString();if(r===Array){if((n=e.length)===t.length)for(;n--&&QA(e[n],t[n]););return n===-1}if(!r||typeof e=="object"){n=0;for(r in e)if(KL.call(e,r)&&++n&&!KL.call(t,r)||!(r in t)||!QA(e[r],t[r]))return!1;return Object.keys(t).length===n}}return e!==e&&t!==t}var zr=new WeakMap,Jr=()=>{},nt=Jr(),Pa=Object,ee=e=>e===nt,Ar=e=>typeof e=="function",Kr=(e,t)=>({...e,...t}),FA=e=>Ar(e.then),rx={},_A={},lx="undefined",Oa=typeof window!=lx,DA=typeof document!=lx,ZL=Oa&&"Deno"in window,eF=()=>Oa&&typeof window.requestAnimationFrame!=lx,PA=(e,t)=>{let r=zr.get(e);return[()=>!ee(t)&&e.get(t)||rx,n=>{if(!ee(t)){let o=e.get(t);t in _A||(_A[t]=o),r[5](t,Kr(o,n),o||rx)}},r[6],()=>!ee(t)&&t in _A?_A[t]:!ee(t)&&e.get(t)||rx]},ix=!0,H7=()=>ix,[sx,ax]=Oa&&window.addEventListener?[window.addEventListener.bind(window),window.removeEventListener.bind(window)]:[Jr,Jr],V7=()=>{let e=DA&&document.visibilityState;return ee(e)||e!=="hidden"},j7=e=>(DA&&document.addEventListener("visibilitychange",e),sx("focus",e),()=>{DA&&document.removeEventListener("visibilitychange",e),ax("focus",e)}),$7=e=>{let t=()=>{ix=!0,e()},r=()=>{ix=!1};return sx("online",t),sx("offline",r),()=>{ax("online",t),ax("offline",r)}},tF={isOnline:H7,isVisible:V7},rF={initFocus:j7,initReconnect:$7},OA=!bt.default.useId,$o=!Oa||ZL,ux=e=>eF()?window.requestAnimationFrame(e):setTimeout(e,1),Ga=$o?bt.useEffect:bt.useLayoutEffect,nx=typeof navigator<"u"&&navigator.connection,cx=!$o&&nx&&(["slow-2g","2g"].includes(nx.effectiveType)||nx.saveData),kA=new WeakMap,W7=e=>Pa.prototype.toString.call(e),ox=(e,t)=>e===`[object ${t}]`,Y7=0,NA=e=>{let t=typeof e,r=W7(e),n=ox(r,"Date"),o=ox(r,"RegExp"),i=ox(r,"Object"),s,a;if(Pa(e)===e&&!n&&!o){if(s=kA.get(e),s)return s;if(s=++Y7+"~",kA.set(e,s),Array.isArray(e)){for(s="@",a=0;a<e.length;a++)s+=NA(e[a])+",";kA.set(e,s)}if(i){s="#";let c=Pa.keys(e).sort();for(;!ee(a=c.pop());)ee(e[a])||(s+=a+":"+NA(e[a])+",");kA.set(e,s)}}else s=n?e.toJSON():t=="symbol"?e.toString():t=="string"?JSON.stringify(e):""+e;return s},Gl=e=>{if(Ar(e))try{e=e()}catch{e=""}let t=e;return e=typeof e=="string"?e:(Array.isArray(e)?e.length:e)?NA(e):"",[e,t]},q7=0,Ol=()=>++q7;async function GA(...e){let[t,r,n,o]=e,i=Kr({populateCache:!0,throwOnError:!0},typeof o=="boolean"?{revalidate:o}:o||{}),s=i.populateCache,a=i.rollbackOnError,c=i.optimisticData,l=A=>typeof a=="function"?a(A):a!==!1,u=i.throwOnError;if(Ar(r)){let A=r,f=[],g=t.keys();for(let h of g)!/^\$(inf|sub)\$/.test(h)&&A(t.get(h)._k)&&f.push(h);return Promise.all(f.map(d))}return d(r);async function d(A){let[f]=Gl(A);if(!f)return;let[g,h]=PA(t,f),[x,w,y,v]=zr.get(t),b=()=>{let k=x[f];return(Ar(i.revalidate)?i.revalidate(g().data,A):i.revalidate!==!1)&&(delete y[f],delete v[f],k&&k[0])?k[0](2).then(()=>g().data):g().data};if(e.length<3)return b();let I=n,S,B=!1,R=Ol();w[f]=[R,0];let D=!ee(c),L=g(),P=L.data,C=L._c,M=ee(C)?P:C;if(D&&(c=Ar(c)?c(M,P):c,h({data:c,_c:M})),Ar(I))try{I=I(M)}catch(k){S=k,B=!0}if(I&&FA(I))if(I=await I.catch(k=>{S=k,B=!0}),R!==w[f][0]){if(B)throw S;return I}else B&&D&&l(S)&&(s=!0,h({data:M,_c:nt}));if(s&&!B)if(Ar(s)){let k=s(I,M);h({data:k,error:nt,_c:nt})}else h({data:I,error:nt,_c:nt});if(w[f][1]=Ol(),Promise.resolve(b()).then(()=>{h({_c:nt})}),B){if(u)throw S;return}return I}}var XL=(e,t)=>{for(let r in e)e[r][0]&&e[r][0](t)},fx=(e,t)=>{if(!zr.has(e)){let r=Kr(rF,t),n=Object.create(null),o=GA.bind(nt,e),i=Jr,s=Object.create(null),a=(u,d)=>{let A=s[u]||[];return s[u]=A,A.push(d),()=>{let f=A.indexOf(d);f>=0&&(A[f]=A[A.length-1],A.pop())}},c=(u,d,A)=>{e.set(u,d);let f=s[u];if(f)for(let g of f)g(d,A)},l=()=>{if(!zr.has(e)&&(zr.set(e,[n,Object.create(null),Object.create(null),Object.create(null),o,c,a]),!$o)){let u=r.initFocus(setTimeout.bind(nt,XL.bind(nt,n,0))),d=r.initReconnect(setTimeout.bind(nt,XL.bind(nt,n,1)));i=()=>{u&&u(),d&&d(),zr.delete(e)}}};return l(),[e,o,l,i]}return[e,zr.get(e)[4]]},z7=(e,t,r,n,o)=>{let i=r.errorRetryCount,s=o.retryCount,a=~~((Math.random()+.5)*(1<<(s<8?s:8)))*r.errorRetryInterval;!ee(i)&&s>i||setTimeout(n,a,o)},nF=QA,[UA,oF]=fx(new Map),HA=Kr({onLoadingSlow:Jr,onSuccess:Jr,onError:Jr,onErrorRetry:z7,onDiscarded:Jr,revalidateOnFocus:!0,revalidateOnReconnect:!0,revalidateIfStale:!0,shouldRetryOnError:!0,errorRetryInterval:cx?1e4:5e3,focusThrottleInterval:5*1e3,dedupingInterval:2*1e3,loadingTimeout:cx?5e3:3e3,compare:nF,isPaused:()=>!1,cache:UA,mutate:oF,fallback:{}},tF),dx=(e,t)=>{let r=Kr(e,t);if(t){let{use:n,fallback:o}=e,{use:i,fallback:s}=t;n&&i&&(r.use=n.concat(i)),o&&s&&(r.fallback=Kr(o,s))}return r},LA=(0,bt.createContext)({}),Ax=e=>{let{value:t}=e,r=(0,bt.useContext)(LA),n=Ar(t),o=(0,bt.useMemo)(()=>n?t(r):t,[n,r,t]),i=(0,bt.useMemo)(()=>n?o:dx(r,o),[n,r,o]),s=o&&o.provider,a=(0,bt.useRef)(nt);s&&!a.current&&(a.current=fx(s(i.cache||UA),o));let c=a.current;return c&&(i.cache=c[0],i.mutate=c[1]),Ga(()=>{if(c)return c[2]&&c[2](),c[3]},[]),(0,bt.createElement)(LA.Provider,Kr(e,{value:i}))};var iF="$inf$";var Ua=p(Q(),1);var sF=Oa&&window.__SWR_DEVTOOLS_USE__,J7=sF?window.__SWR_DEVTOOLS_USE__:[],K7=()=>{sF&&(window.__SWR_DEVTOOLS_REACT__=Ua.default)},X7=e=>Ar(e[1])?[e[0],e[1],e[2]||{}]:[e[0],null,(e[1]===null?e[2]:e[1])||{}],Z7=()=>{let e=(0,Ua.useContext)(LA);return(0,Ua.useMemo)(()=>Kr(HA,e),[e])};var e$=e=>(t,r,n)=>e(t,r&&((...i)=>{let[s]=Gl(t),[,,,a]=zr.get(UA);if(s.startsWith(iF))return r(...i);let c=a[s];return ee(c)?r(...i):(delete a[s],c)}),n),t$=J7.concat(e$),aF=e=>function(...r){let n=Z7(),[o,i,s]=X7(r),a=dx(n,s),c=e,{use:l}=a,u=(l||[]).concat(t$);for(let d=u.length;d--;)c=u[d](c);return c(o,i||a.fetcher||null,a)},cF=(e,t,r)=>{let n=t[e]||(t[e]=[]);return n.push(r),()=>{let o=n.indexOf(r);o>=0&&(n[o]=n[n.length-1],n.pop())}};K7();var r$=()=>{},Ghe=r$();var mx=at.default.use||(e=>{switch(e.status){case"pending":throw e;case"fulfilled":return e.value;case"rejected":throw e.reason;default:throw e.status="pending",e.then(t=>{e.status="fulfilled",e.value=t},t=>{e.status="rejected",e.reason=t}),e}}),px={dedupe:!0},VA=Promise.resolve(nt);VA.status="fulfilled";VA.value=nt;var n$=()=>Jr,o$=(e,t,r)=>{let{cache:n,compare:o,suspense:i,fallbackData:s,revalidateOnMount:a,revalidateIfStale:c,refreshInterval:l,refreshWhenHidden:u,refreshWhenOffline:d,keepPreviousData:A,strictServerPrefetchWarning:f}=r,[g,h,x,w]=zr.get(n),[y,v]=Gl(e),b=(0,at.useRef)(!1),I=(0,at.useRef)(!1),S=(0,at.useRef)(y),B=(0,at.useRef)(t),R=(0,at.useRef)(r),D=()=>R.current,L=()=>D().isVisible()&&D().isOnline(),[P,C,M,k]=PA(n,y),G=(0,at.useRef)({}).current,j=ee(s)?ee(r.fallback)?nt:r.fallback[y]:s,oe=(me,ae)=>{for(let ke in G){let Be=ke;if(Be==="data"){if(!o(me[Be],ae[Be])&&(!ee(me[Be])||!o(Ji,ae[Be])))return!1}else if(ae[Be]!==me[Be])return!1}return!0},te=!b.current,kr=(0,at.useMemo)(()=>{let me=P(),ae=k(),ke=ye=>{let ze=Kr(ye);return delete ze._k,(()=>{if(!y||!t||D().isPaused())return!1;if(te&&!ee(a))return a;let Ln=ee(j)?ze.data:j;return i?ee(Ln)||c:ee(Ln)||c})()?{isValidating:!0,isLoading:!0,...ze}:ze},Be=ke(me),er=me===ae?Be:ke(ae),Nt=Be;return[()=>{let ye=ke(P());return oe(ye,Nt)?(Nt.data=ye.data,Nt.isLoading=ye.isLoading,Nt.isValidating=ye.isValidating,Nt.error=ye.error,Nt):(Nt=ye,ye)},()=>er]},[n,y]),ot=(0,gx.useSyncExternalStore)((0,at.useCallback)(me=>M(y,(ae,ke)=>{oe(ke,ae)||me()}),[n,y]),kr[0],kr[1]),Ae=g[y]&&g[y].length>0,Dr=ot.data,mr=ee(Dr)?j&&FA(j)?mx(j):j:Dr,nn=ot.error,Dn=(0,at.useRef)(mr),Ji=A?ee(Dr)?ee(Dn.current)?mr:Dn.current:Dr:mr,Nn=y&&ee(mr),io=(0,at.useRef)(null);!$o&&(0,gx.useSyncExternalStore)(n$,()=>(io.current=!1,io),()=>(io.current=!0,io));let em=io.current;f&&em&&!i&&Nn&&console.warn(`Missing pre-initiated data for serialized key "${y}" during server-side rendering. Data fetching should be initiated on the server and provided to SWR via fallback data. You can set "strictServerPrefetchWarning: false" to disable this warning.`);let $a=!y||!t||D().isPaused()||Ae&&!ee(nn)?!1:te&&!ee(a)?a:i?ee(mr)?!1:c:ee(mr)||c,Se=te&&$a,Wl=ee(ot.isValidating)?Se:ot.isValidating,_e=ee(ot.isLoading)?Se:ot.isLoading,so=(0,at.useCallback)(async me=>{let ae=B.current;if(!y||!ae||I.current||D().isPaused())return!1;let ke,Be,er=!0,Nt=me||{},ye=!x[y]||!Nt.dedupe,ze=()=>OA?!I.current&&y===S.current&&b.current:y===S.current,tr={isValidating:!1,isLoading:!1},Ln=()=>{C(tr)},Xi=()=>{let It=x[y];It&&It[1]===Be&&delete x[y]},Zi={isValidating:!0};ee(P().data)&&(Zi.isLoading=!0);try{if(ye&&(C(Zi),r.loadingTimeout&&ee(P().data)&&setTimeout(()=>{er&&ze()&&D().onLoadingSlow(y,r)},r.loadingTimeout),x[y]=[ae(v),Ol()]),[ke,Be]=x[y],ke=await ke,ye&&setTimeout(Xi,r.dedupingInterval),!x[y]||x[y][1]!==Be)return ye&&ze()&&D().onDiscarded(y),!1;tr.error=nt;let It=h[y];if(!ee(It)&&(Be<=It[0]||Be<=It[1]||It[1]===0))return Ln(),ye&&ze()&&D().onDiscarded(y),!1;let St=P().data;tr.data=o(St,ke)?St:ke,ye&&ze()&&D().onSuccess(ke,y,r)}catch(It){Xi();let St=D(),{shouldRetryOnError:ao}=St;St.isPaused()||(tr.error=It,ye&&ze()&&(St.onError(It,y,St),(ao===!0||Ar(ao)&&ao(It))&&(!D().revalidateOnFocus||!D().revalidateOnReconnect||L())&&St.onErrorRetry(It,y,St,es=>{let ts=g[y];ts&&ts[0]&&ts[0](jo.ERROR_REVALIDATE_EVENT,es)},{retryCount:(Nt.retryCount||0)+1,dedupe:!0})))}return er=!1,Ln(),!0},[y,n]),ve=(0,at.useCallback)((...me)=>GA(n,S.current,...me),[]);if(Ga(()=>{B.current=t,R.current=r,ee(Dr)||(Dn.current=Dr)}),Ga(()=>{if(!y)return;let me=so.bind(nt,px),ae=0;D().revalidateOnFocus&&(ae=Date.now()+D().focusThrottleInterval);let Be=cF(y,g,(er,Nt={})=>{if(er==jo.FOCUS_EVENT){let ye=Date.now();D().revalidateOnFocus&&ye>ae&&L()&&(ae=ye+D().focusThrottleInterval,me())}else if(er==jo.RECONNECT_EVENT)D().revalidateOnReconnect&&L()&&me();else{if(er==jo.MUTATE_EVENT)return so();if(er==jo.ERROR_REVALIDATE_EVENT)return so(Nt)}});return I.current=!1,S.current=y,b.current=!0,C({_k:v}),$a&&(x[y]||(ee(mr)||$o?me():ux(me))),()=>{I.current=!0,Be()}},[y]),Ga(()=>{let me;function ae(){let Be=Ar(l)?l(P().data):l;Be&&me!==-1&&(me=setTimeout(ke,Be))}function ke(){!P().error&&(u||D().isVisible())&&(d||D().isOnline())?so(px).then(ae):ae()}return ae(),()=>{me&&(clearTimeout(me),me=-1)}},[l,u,d,y]),(0,at.useDebugValue)(Ji),i){if(!OA&&$o&&Nn)throw new Error("Fallback data is required when using Suspense in SSR.");Nn&&(B.current=t,R.current=r,I.current=!1);let me=w[y],ae=!ee(me)&&Nn?ve(me):VA;if(mx(ae),!ee(nn)&&Nn)throw nn;let ke=Nn?so(px):VA;!ee(Ji)&&Nn&&(ke.status="fulfilled",ke.value=!0),mx(ke)}return{mutate:ve,get data(){return G.data=!0,Ji},get error(){return G.error=!0,nn},get isValidating(){return G.isValidating=!0,Wl},get isLoading(){return G.isLoading=!0,_e}}},Uhe=Pa.defineProperty(Ax,"defaultValue",{value:HA}),$i=aF(o$);var Wi={revalidateOnFocus:!1,revalidateOnReconnect:!1,revalidateIfStale:!1,refreshWhenHidden:!1,refreshWhenOffline:!1,shouldRetryOnError:!1};function jA(e){let{data:t,error:r,isLoading:n,mutate:o}=$i(`cached-blast-${e.join(",")}`,async()=>(await wN()).filter(c=>c.geneId&&e.includes(c.geneId)),Wi);return{results:t??[],error:r,isLoading:n,handleDelete:async a=>{await Py(a),await o(c=>c?.filter(l=>l.id!==a)??[],!1)},handleClearAll:async()=>{await Promise.all((t??[]).map(a=>Py(a.id))),await o([],!1)}}}var i$=(0,dF.makeStyles)()({header:{display:"flex",justifyContent:"space-between",alignItems:"center",marginBottom:8},resultList:{maxHeight:300,overflow:"auto"}});function lF(e){let t=[e.geneName,e.transcriptName!==e.geneName?e.transcriptName:void 0].filter(r=>!!r);return t.length>0?t.join(" - "):e.geneId??e.transcriptId??"Unknown"}var s$=(0,fF.observer)(function({model:e,handleClose:t,feature:r}){let{classes:n}=i$(),o=Rr(e),[i,s]=(0,pt.useState)(),a=(0,pt.useMemo)(()=>Ra(r),[r]),{results:c,error:l,isLoading:u,handleDelete:d,handleClearAll:A}=jA(a),f=h=>{let{transcriptId:x}=h,w=x?CA(r).find(y=>Ba(y,x)):void 0;VL({view:o,cached:h,newViewTitle:`BLAST - ${lF(h)}`,connectedFeature:w?.toJSON()}),t()},g=l??i;return g?pt.default.createElement(uF.ErrorMessage,{error:g}):u?pt.default.createElement(kt.Typography,null,"Loading cached results..."):c.length===0?pt.default.createElement(kt.Typography,{color:"textSecondary"},"No cached BLAST results found for this gene. Run a BLAST query to cache results."):pt.default.createElement("div",null,pt.default.createElement("div",{className:n.header},pt.default.createElement(kt.Typography,{variant:"subtitle1"},"Cached BLAST Results (",c.length,")"),pt.default.createElement(kt.Button,{size:"small",color:"error",onClick:async()=>{try{s(void 0),await A()}catch(h){s(h)}}},"Clear results for this gene")),pt.default.createElement(kt.List,{dense:!0,className:n.resultList},c.map(h=>pt.default.createElement(kt.ListItem,{key:h.id,disablePadding:!0,secondaryAction:pt.default.createElement(kt.IconButton,{edge:"end",size:"small",onClick:async x=>{x.stopPropagation();try{s(void 0),await d(h.id)}catch(w){s(w)}}},pt.default.createElement(UL,{fontSize:"small"}))},pt.default.createElement(kt.ListItemButton,{onClick:()=>{f(h)}},pt.default.createElement(kt.ListItemText,{primary:`${lF(h)} - ${h.blastDatabase}${h.blastProgram?`/${h.blastProgram}`:""} (${h.msaAlgorithm})`,secondary:`${new Date(h.timestamp).toLocaleString()} - Seq: ${h.proteinSequence.slice(0,30)}...`}))))))}),AF=s$;var xx=p(Q()),yF=p(U());var hx="https://blast.ncbi.nlm.nih.gov/Blast.cgi",mF=["clustalo","muscle","kalign","mafft"],pF=["uniprotkb_swissprot","uniprotkb","uniprotkb_reference_proteomes","uniprotkb_trembl"],gF="uniprotkb_swissprot";var yx=p(Q()),hF=p(U());function a$({children:e,...t}){return yx.default.createElement("div",null,yx.default.createElement(hF.TextField,{...t},e))}var gt=a$;function Ul({value:e,onChange:t,className:r}){return xx.default.createElement(gt,{variant:"outlined",label:"MSA Algorithm",className:r,select:!0,value:e,onChange:n=>{t(n.target.value)}},mF.map(n=>xx.default.createElement(yF.MenuItem,{value:n,key:n},n)))}var Cx=p(Q()),xF=p(Xe()),CF=p(U()),EF=p(Ut()),c$=(0,EF.makeStyles)()({dialogContent:{width:"80em"}});function Xr({error:e,children:t}){let{classes:r}=c$();return Cx.default.createElement(CF.DialogContent,{className:r.dialogContent},e?Cx.default.createElement(xF.ErrorMessage,{error:e}):null,t)}var $A=p(Q()),Hl=p(U());function oo({onSubmit:e,onCancel:t,submitDisabled:r,submitLabel:n="Submit",cancelLabel:o="Cancel"}){return $A.default.createElement(Hl.DialogActions,null,$A.default.createElement(Hl.Button,{color:"primary",variant:"contained",disabled:r,onClick:()=>{e()}},n),$A.default.createElement(Hl.Button,{color:"secondary",variant:"contained",onClick:()=>{t()}},o))}var Zr=p(Q()),Ha=p(U()),IF=p(Ut());var bF=p(Q()),wF=p(Ut());var l$=(0,wF.makeStyles)()({textAreaFont:{fontFamily:"Courier New"}});function Ex({value:e}){let{classes:t}=l$();return bF.default.createElement(gt,{variant:"outlined",multiline:!0,minRows:5,maxRows:10,fullWidth:!0,value:e,slotProps:{input:{readOnly:!0,classes:{input:t.textAreaFont}}}})}var u$=(0,IF.makeStyles)()({flex:{display:"flex"},minWidth:{minWidth:300},centered:{alignContent:"center",marginLeft:20}});function en({feature:e,options:t,selectedId:r,selectedTranscript:n,setSelectedId:o,proteinSequence:i,validIds:s}){let{classes:a}=u$(),[c,l]=(0,Zr.useState)(!1);return Zr.default.createElement(Zr.default.Fragment,null,Zr.default.createElement("div",{className:a.flex},Zr.default.createElement(Ha.TextField,{variant:"outlined",label:`Choose isoform of ${no(e)}`,helperText:"the query row, so the alignment stays linked to the genome view",select:!0,className:a.minWidth,value:r,onChange:u=>{o(u.target.value)}},t.map(u=>{let d=s?s.some(g=>Ba(u,g)):!0,{len:A,mod:f}=yA(u);return Zr.default.createElement(Ha.MenuItem,{value:Hi(u),key:u.id(),disabled:!d},Ta(u)," (",A," aa)"," ",f?" (possible fragment)":"",s?d?" (has data)":" (no data)":"")})),Zr.default.createElement("div",{className:a.centered},Zr.default.createElement(Ha.Button,{variant:"contained",color:"primary",onClick:()=>{l(!c)}},c?"Hide sequence":"Show sequence"))),c?Zr.default.createElement(Ex,{value:i?`>${Ta(n)}
+${i}`:"Loading..."}):null)}var YA=p(Q());var WA=p(be());mQ();function SF({cds:e,sequence:t,codonTable:r}){let n=e[0]?.phase??0,o=AQ(e,t),i=n>0?"&":"";for(let s=n;s<o.length;s+=3)i+=r[o.slice(s,s+3)]||"&";return i}var f$=[{id:1,name:"Standard",ncbieaa:"FFLLSSSSYY**CC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"---M------**--*----M---------------M----------------------------"},{id:2,name:"Vertebrate Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNKKSS**VVVVAAAADDEEGGGG",sncbieaa:"----------**--------------------MMMM----------**---M------------"},{id:3,name:"Yeast Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWTTTTPPPPHHQQRRRRIIMMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**----------------------MM---------------M------------"},{id:4,name:"Mold Mitochondrial; Protozoan Mitochondrial; Coelenterate Mitochondrial; Mycoplasma; Spiroplasma",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--MM------**-------M------------MMMM---------------M------------"},{id:5,name:"Invertebrate Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNKKSSSSVVVVAAAADDEEGGGG",sncbieaa:"---M------**--------------------MMMM---------------M------------"},{id:6,name:"Ciliate Nuclear; Dasycladacean Nuclear; Hexamita Nuclear",ncbieaa:"FFLLSSSSYYQQCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--------------*--------------------M----------------------------"},{id:9,name:"Echinoderm Mitochondrial; Flatworm Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNNKSSSSVVVVAAAADDEEGGGG",sncbieaa:"----------**-----------------------M---------------M------------"},{id:10,name:"Euplotid Nuclear",ncbieaa:"FFLLSSSSYY**CCCWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**-----------------------M----------------------------"},{id:11,name:"Bacterial, Archaeal and Plant Plastid",ncbieaa:"FFLLSSSSYY**CC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"---M------**--*----M------------MMMM---------------M------------"},{id:12,name:"Alternative Yeast Nuclear",ncbieaa:"FFLLSSSSYY**CC*WLLLSPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**--*----M---------------M----------------------------"},{id:13,name:"Ascidian Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNKKSSGGVVVVAAAADDEEGGGG",sncbieaa:"---M------**----------------------MM---------------M------------"},{id:14,name:"Alternative Flatworm Mitochondrial",ncbieaa:"FFLLSSSSYYY*CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNNKSSSSVVVVAAAADDEEGGGG",sncbieaa:"-----------*-----------------------M----------------------------"},{id:15,name:"Blepharisma Macronuclear",ncbieaa:"FFLLSSSSYY*QCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------*---*--------------------M----------------------------"},{id:16,name:"Chlorophycean Mitochondrial",ncbieaa:"FFLLSSSSYY*LCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------*---*--------------------M----------------------------"},{id:21,name:"Trematode Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNNKSSSSVVVVAAAADDEEGGGG",sncbieaa:"----------**-----------------------M---------------M------------"},{id:22,name:"Scenedesmus obliquus Mitochondrial",ncbieaa:"FFLLSS*SYY*LCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"------*---*---*--------------------M----------------------------"},{id:23,name:"Thraustochytrium Mitochondrial",ncbieaa:"FF*LSSSSYY**CC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--*-------**--*-----------------M--M---------------M------------"},{id:24,name:"Rhabdopleuridae Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSSKVVVVAAAADDEEGGGG",sncbieaa:"---M------**-------M---------------M---------------M------------"},{id:25,name:"Candidate Division SR1 and Gracilibacteria",ncbieaa:"FFLLSSSSYY**CCGWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"---M------**-----------------------M---------------M------------"},{id:26,name:"Pachysolen tannophilus Nuclear",ncbieaa:"FFLLSSSSYY**CC*WLLLAPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**--*----M---------------M----------------------------"},{id:27,name:"Karyorelict Nuclear",ncbieaa:"FFLLSSSSYYQQCCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--------------*--------------------M----------------------------"},{id:28,name:"Condylostoma Nuclear",ncbieaa:"FFLLSSSSYYQQCCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**--*--------------------M----------------------------"},{id:29,name:"Mesodinium Nuclear",ncbieaa:"FFLLSSSSYYYYCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--------------*--------------------M----------------------------"},{id:30,name:"Peritrich Nuclear",ncbieaa:"FFLLSSSSYYEECC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--------------*--------------------M----------------------------"},{id:31,name:"Blastocrithidia Nuclear",ncbieaa:"FFLLSSSSYYEECCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**-----------------------M----------------------------"},{id:32,name:"Balanophoraceae Plastid",ncbieaa:"FFLLSSSSYY*WCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"---M------*---*----M------------MMMM---------------M------------"},{id:33,name:"Cephalodiscidae Mitochondrial",ncbieaa:"FFLLSSSSYYY*CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSSKVVVVAAAADDEEGGGG",sncbieaa:"---M-------*-------M---------------M---------------M------------"}],d$="TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG",A$="TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG",m$="TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG",p$=Array.from({length:64},(e,t)=>d$[t]+A$[t]+m$[t]),vF=new Map(f$.map(e=>[e.id,e]));function g$(e){let t={};for(let[r,n]of Object.entries(e)){let o=i=>{let s=r.charAt(i);return[s.toUpperCase(),s.toLowerCase()]};for(let i of o(0))for(let s of o(1))for(let a of o(2))t[i+s+a]=n}return t}function h$(e){let t=vF.get(e);!t&&e!==1&&console.warn(`Unknown genetic code (transl_table=${e}); using standard code`);let{id:r,name:n,ncbieaa:o,sncbieaa:i}=t??vF.get(1),s={},a=[];for(let[c,l]of p$.entries())s[l]=o[c],i[c]==="M"&&a.push(l);return{id:r,name:n,codonTable:g$(s),starts:a}}var BF=new Map;function TF(e=1){let t=BF.get(e);return t||(t=h$(e),BF.set(e,t)),t}function bx(e){let t=Array.isArray(e)?e[0]:e,r=Number(t);return Number.isInteger(r)&&r>0?r:void 0}function y$({cds:e,sequence:t,geneticCodeId:r}){let{codonTable:n}=TF(r);return SF({cds:e,sequence:t,codonTable:n})}function x$(e,t){return e.map(r=>({...r,start:t-r.end,end:t-r.start})).toSorted((r,n)=>r.start-n.start)}function MF({feature:e,seq:t}){let{subfeatures:r,start:n,strand:o}=e.toJSON(),i=(0,WA.dedupe)(r?.toSorted((c,l)=>c.start-l.start).map(c=>({...c,start:c.start-n,end:c.end-n})).filter(c=>c.type==="CDS")??[],c=>`${c.start}-${c.end}`),s=e.get("subfeatures")?.find(c=>c.get("type")?.toLowerCase()==="cds"),a=bx(e.get("transl_table"))??bx(s?.get("transl_table"));return y$({cds:o===-1?x$(i,t.length):i,sequence:o===-1?(0,WA.revcom)(t):t,geneticCodeId:a})}var _F=p(be());var RF=p(ss());async function QF({start:e,end:t,refName:r,session:n,assemblyName:o}){let{assemblyManager:i,rpcManager:s}=n,a=await i.waitForAssembly(o);if(!a)throw new Error("assembly not found");let c="getSequence";return(await s.call(c,"CoreGetFeatures",{adapterConfig:(0,RF.getConf)(a,["sequence","adapter"]),sessionId:c,regions:[{start:e,end:t,refName:a.getCanonicalRefName(r),assemblyName:o}]}))[0]?.get("seq")??""}async function C$({feature:e,assemblyName:t,view:r}){let n=(0,_F.getSession)(r),{start:o,end:i,refName:s}=e.toJSON();return{seq:await QF({start:o,end:i,refName:s,assemblyName:t,session:n})}}function kF({view:e,feature:t}){let r=e?.assemblyNames?.[0],n=t&&r?{feature:t,assemblyName:r,view:e}:void 0,{data:o,error:i}=$i(n?[n.feature.id(),n.assemblyName,"feature-sequence"]:null,()=>C$(n),Wi);return{sequence:o,error:i}}function DF({view:e,feature:t}){let{sequence:r,error:n}=kF({view:e,feature:t});return{proteinSequence:r&&t?MF({seq:r.seq,feature:t}):"",sequence:r,error:n}}function E$(e,t,r){if(!r?.length)return e;let n=s=>r.some(a=>Ba(s,a)),o=t.find(s=>Hi(s)===e);if(o&&n(o))return e;let i=t.find(n);return i?Hi(i):e}function Rn({feature:e,view:t,validIds:r}){let n=(0,YA.useMemo)(()=>CA(e),[e]),[o,i]=(0,YA.useState)(()=>Hi(n[0])),s=E$(o,n,r),a=n.find(u=>Hi(u)===s),{proteinSequence:c,error:l}=DF({view:t,feature:a});return{options:n,selectedId:s,setSelectedId:i,selectedTranscript:a,proteinSequence:c,error:l,validIds:r}}var b$=(0,LF.makeStyles)()({selectField:{width:150},cachedResultsAccordion:{marginTop:20},infoText:{marginTop:20}}),w$=(0,NF.observer)(function({handleClose:e,feature:t,model:r,children:n}){let{classes:o}=b$(),i=Rr(r),[s,a]=(0,je.useState)(),[c,l]=(0,je.useState)(gF),[u,d]=(0,je.useState)("clustalo"),A=(0,je.useMemo)(()=>Ra(t),[t]),{results:f,error:g}=jA(A),h=Rn({feature:t,view:i}),{selectedTranscript:x,proteinSequence:w}=h,y=h.error??s??g;return je.default.createElement(je.default.Fragment,null,je.default.createElement(Xr,{error:y},n,je.default.createElement(gt,{variant:"outlined",label:"BLAST database",className:o.selectField,select:!0,value:c,onChange:v=>{l(v.target.value)}},pF.map(v=>je.default.createElement(tn.MenuItem,{value:v,key:v},v))),je.default.createElement(Ul,{className:o.selectField,value:u,onChange:d}),je.default.createElement(en,{feature:t,...h}),je.default.createElement(tn.Typography,{className:o.infoText},"This panel will automatically submit a blastp query to EBI, which searches UniProtKB. Searches usually finish in under a minute, and swissprot returns curated sequences that align more cleanly than the many near-identical entries a TrEMBL search brings back. After completion, all the hits will be run through a multiple sequence alignment. Searching NCBI's nr needs the manual approach: NCBI no longer lets a browser read responses from Blast.cgi."),f.length>0?je.default.createElement(tn.Accordion,{className:o.cachedResultsAccordion},je.default.createElement(tn.AccordionSummary,{expandIcon:je.default.createElement(eA,null)},je.default.createElement(tn.Typography,null,"Previous BLAST Results")),je.default.createElement(tn.AccordionDetails,null,je.default.createElement(AF,{model:r,handleClose:e,feature:t}))):null),je.default.createElement(oo,{submitDisabled:!w,onSubmit:()=>{try{x&&(a(void 0),HL({feature:x,view:i,newViewTitle:EN(t,x),blastParams:{blastDatabase:c,msaAlgorithm:u,selectedTranscript:x,proteinSequence:w}}),e())}catch(v){console.error(v),a(v)}},onCancel:e}))}),FF=w$;var Qn=p(Q()),HF=p(be()),Va=p(U()),VF=p(Y()),jF=p(Ut());Ix();var I$=(0,jF.makeStyles)()({ncbiLink:{wordBreak:"break-all",margin:30,maxWidth:600},infoText:{marginTop:20}}),S$=(0,VF.observer)(function({handleClose:e,feature:t,model:r,children:n}){let{classes:o}=I$(),i=Rr(r),s=Rn({feature:t,view:i}),{proteinSequence:a,error:c}=s,l=Ma(a),u=`${hx}?PAGE_TYPE=BlastSearch&PAGE=Proteins&PROGRAM=blastp&QUERY=${l}`,d=`${hx}?PAGE_TYPE=BlastSearch&PAGE=Proteins&PROGRAM=blastp&QUERY=${(0,HF.shorten2)(l,10)}`;return Qn.default.createElement(Qn.default.Fragment,null,Qn.default.createElement(Xr,{error:c},n,Qn.default.createElement(en,{feature:t,...s}),a?Qn.default.createElement("div",{className:o.ncbiLink},"Link to NCBI BLAST: ",Qn.default.createElement(Vl,{href:u},d)):null,Qn.default.createElement(Va.Typography,{className:o.infoText},`Click the link above and run your BLAST query, and once you have results, click "Multiple Alignment" at the top of the results page to be redirected to COBALT, NCBI's multiple sequence aligner. Once COBALT completes, you can download an MSA (.aln file) and optionally a Newick tree (.nh) and paste the results into JBrowse`)),Qn.default.createElement(Va.DialogActions,null,Qn.default.createElement(Va.Button,{color:"primary",variant:"contained",onClick:()=>{e()}},"Close")))}),$F=S$;var Yi=p(Q()),_n=p(U());function Sx({lookupMethod:e,setLookupMethod:t}){return Yi.default.createElement(_n.FormControl,{component:"fieldset"},Yi.default.createElement(_n.RadioGroup,{row:!0,value:e,onChange:r=>{t(r.target.value)}},Yi.default.createElement(_n.FormControlLabel,{value:"automatic",control:Yi.default.createElement(_n.Radio,null),label:"Automatic"}),Yi.default.createElement(_n.FormControlLabel,{value:"manual",control:Yi.default.createElement(_n.Radio,null),label:"Manual"})))}var Qr=p(Q()),Zt=p(U()),WF=p(Ut());Dl();var v$=(0,WF.makeStyles)()({field:{minWidth:300},help:{marginBottom:8}});function vx({handleClose:e,ebiEmail:t}){let{classes:r}=v$(),[n,o]=(0,Qr.useState)(t);return Qr.default.createElement(Zt.Dialog,{open:!0,maxWidth:"lg",onClose:()=>{e()}},Qr.default.createElement(Zt.DialogTitle,null,"BLAST Settings"),Qr.default.createElement(Zt.DialogContent,null,Qr.default.createElement(Zt.Typography,{variant:"subtitle2",className:r.help},"Searches run at EBI, which asks for a contact address on every job so they can reach whoever is generating the load. If your site sends real volume, use your own."),Qr.default.createElement(gt,{autoFocus:!0,margin:"dense",label:"EBI contact email",fullWidth:!0,variant:"outlined",value:n,className:r.field,onChange:i=>{o(i.target.value)}}),Qr.default.createElement(Zt.Button,{variant:"contained",onClick:()=>{o(_a)}},"Reset")),Qr.default.createElement(Zt.DialogActions,null,Qr.default.createElement(Zt.Button,{variant:"contained",color:"secondary",onClick:()=>{e()}},"Cancel"),Qr.default.createElement(Zt.Button,{color:"primary",variant:"contained",onClick:()=>{e({ebiEmail:n})}},"Save")))}Dl();Gy();var B$=(0,qF.makeStyles)()({settingsButton:{float:"right"}}),T$={automatic:FF,manual:$F};function Bx({handleClose:e,model:t,feature:r}){let[n,o]=(0,rn.useState)("automatic"),[i,s]=MN(Hy,_a),[a,c]=(0,rn.useState)(!1),{classes:l}=B$(),u=T$[n];return rn.default.createElement(rn.default.Fragment,null,rn.default.createElement(YF.IconButton,{className:l.settingsButton,size:"small",onClick:()=>{c(!0)}},rn.default.createElement(OL,null)),rn.default.createElement(u,{model:t,feature:r,handleClose:e},rn.default.createElement(Sx,{lookupMethod:n,setLookupMethod:o})),a?rn.default.createElement(vx,{ebiEmail:i,handleClose:d=>{d&&s(d.ebiEmail),c(!1)}}):null)}var de=p(Q()),Tx=p(Xe()),_r=p(U()),KF=p(Y()),XF=p(Ut());var zF=p(be());function JF({newViewTitle:e,view:t,feature:r,msaFilehandle:n,treeFilehandle:o,querySeqName:i,data:s}){(0,zF.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,connectedViewId:t.id,connectedFeature:r.toJSON(),msaFilehandle:n,treeFilehandle:o,querySeqName:i,data:s})}var M$=(0,XF.makeStyles)()({textAreaFont:{fontFamily:"Courier New"},inputContainer:{marginBottom:30},fileContainer:{maxWidth:500},msaInput:{marginBottom:20},queryNameInput:{marginTop:20},warningAlert:{marginTop:10}}),R$=(0,KF.observer)(function({model:t,feature:r,handleClose:n}){let o=Rr(t),{classes:i}=M$(),[s,a]=(0,de.useState)(),[c,l]=(0,de.useState)("file"),[u,d]=(0,de.useState)(""),[A,f]=(0,de.useState)(""),[g,h]=(0,de.useState)(),[x,w]=(0,de.useState)(),[y,v]=(0,de.useState)(""),b=Rn({feature:r,view:o}),{selectedTranscript:I,error:S}=b;return de.default.createElement(de.default.Fragment,null,de.default.createElement(Xr,{error:s??S},de.default.createElement(_r.FormControl,{component:"fieldset"},de.default.createElement(_r.RadioGroup,{row:!0,value:c,onChange:R=>{l(R.target.value)}},de.default.createElement(_r.FormControlLabel,{value:"file",control:de.default.createElement(_r.Radio,null),label:"Open files"}),de.default.createElement(_r.FormControlLabel,{value:"text",control:de.default.createElement(_r.Radio,null),label:"Paste text"}))),de.default.createElement("div",{className:i.inputContainer},c==="file"?de.default.createElement("div",{className:i.fileContainer},de.default.createElement(Tx.FileSelector,{name:"MSA File .aln (Clustal), .fa/.mfa (aligned FASTA), .stock (Stockholm), etc)",inline:!0,location:g,setLocation:h}),de.default.createElement(Tx.FileSelector,{name:"Tree file .nh (Newick) or .asn (NCBI COBALT ASN.1)",inline:!0,location:x,setLocation:w})):de.default.createElement(de.default.Fragment,null,de.default.createElement(gt,{variant:"outlined",name:"MSA",multiline:!0,minRows:5,className:i.msaInput,maxRows:10,fullWidth:!0,placeholder:"Paste MSA here",value:u,onChange:R=>{d(R.target.value)}}),de.default.createElement(gt,{variant:"outlined",name:"Tree",multiline:!0,minRows:5,maxRows:10,fullWidth:!0,placeholder:"Paste newick tree (optional)",value:A,onChange:R=>{f(R.target.value)}}))),de.default.createElement(en,{feature:r,...b}),de.default.createElement(gt,{variant:"outlined",name:"MSA row name",fullWidth:!0,required:!0,className:i.queryNameInput,placeholder:"Row name in MSA that corresponds to the selected transcript",helperText:"Required: Specify the name of the row in your MSA that should be aligned with the selected transcript",value:y,onChange:R=>{v(R.target.value)}}),y.trim()?null:de.default.createElement(_r.Alert,{severity:"warning",className:i.warningAlert},"Without specifying the MSA row name, clicking on the MSA will not navigate to the corresponding genome position, and hovering highlights will not work.")),de.default.createElement(oo,{submitDisabled:!I||c==="file"&&!g||c==="text"&&!u.trim(),onSubmit:()=>{try{I&&(a(void 0),JF({newViewTitle:no(I),view:o,feature:I,querySeqName:y.trim(),...c==="file"?{msaFilehandle:g,treeFilehandle:x}:{data:{msa:u,tree:A}}}),n())}catch(R){console.error(R),a(R)}},onCancel:n}))}),ZF=R$;var ht=p(Q()),nP=p(U()),oP=p(Y()),iP=p(Ut());var Wo=p(Q());ji();var Q$="https://eutils.ncbi.nlm.nih.gov/entrez/eutils";async function eP(e){let t=e.trim();if(!t)return;if(/^\d+$/.test(t))return Number(t);let r=new URLSearchParams({db:"taxonomy",term:t,retmode:"json",retmax:"1",tool:ka,email:Da}),o=(await Qa(`${Q$}/esearch.fcgi?${r.toString()}`)).esearchresult?.idlist?.[0];return o?Number(o):void 0}function Mx({value:e,onChange:t,className:r}){let[n,o]=(0,Wo.useState)("human"),[i,s]=(0,Wo.useState)(),[a,c]=(0,Wo.useState)();return(0,Wo.useEffect)(()=>{let l={live:!0},u=()=>!l.live;async function d(){try{c(void 0);let f=await eP(n);if(u())return;if(!f){s(void 0),c(new Error(`No NCBI taxon matches "${n}"`));return}let g=(await Na([f])).get(f);if(u())return;s([g?.sciname,g?.commonName&&`(${g.commonName})`].filter(Boolean).join(" ")||`taxon ${f}`),t(f)}catch(f){u()||c(f)}}let A=setTimeout(()=>{d()},400);return()=>{l.live=!1,clearTimeout(A)}},[n]),Wo.default.createElement(gt,{variant:"outlined",label:"Query species",className:r,value:n,onChange:l=>{o(l.target.value)},error:!!a,helperText:a?`${a}`:i??`the species this gene is from (taxon ${e})`})}var tP=p(be());function rP({newViewTitle:e,view:t,feature:r,orthologParams:n}){(0,tP.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,connectedViewId:t.id,connectedFeature:r.toJSON(),drawNodeBubbles:!0,colWidth:10,rowHeight:12,orthologParams:n})}var _$=(0,iP.makeStyles)()({selectField:{width:180}}),k$=(0,oP.observer)(function({handleClose:e,feature:t,model:r}){let{classes:n}=_$(),o=Rr(r),[i,s]=(0,ht.useState)(),[a,c]=(0,ht.useState)(9606),[l,u]=(0,ht.useState)("clustalo"),[d,A]=(0,ht.useState)(String(jy)),f=(0,ht.useMemo)(()=>Ra(t),[t]),g=Rn({feature:t,view:o}),{selectedTranscript:h,proteinSequence:x}=g,w=g.error??i,y=Number(d),v=Number.isInteger(y)&&y>=2;return ht.default.createElement(ht.default.Fragment,null,ht.default.createElement(Xr,{error:w},ht.default.createElement(nP.Typography,{variant:"body2"},"NCBI's precomputed orthologs, one gene per species, looked up rather than searched for. No BLAST job to queue."),ht.default.createElement("div",null,ht.default.createElement(Mx,{className:n.selectField,value:a,onChange:c}),ht.default.createElement(Ul,{className:n.selectField,value:l,onChange:u}),ht.default.createElement(gt,{variant:"outlined",label:"Rows to align",className:n.selectField,type:"number",value:d,onChange:b=>{A(b.target.value)},error:!v,helperText:"the closest N species NCBI has"})),ht.default.createElement(en,{feature:t,...g})),ht.default.createElement(oo,{submitDisabled:!x||!v,onSubmit:()=>{try{h&&(s(void 0),rP({feature:h,view:o,newViewTitle:`Orthologs - ${no(t)} - ${Ta(h)}`,orthologParams:{taxId:a,maxSpecies:y,geneCandidates:f,msaAlgorithm:l,selectedTranscript:h,proteinSequence:x}}),e())}catch(b){console.error(b),s(b)}},onCancel:e}))}),sP=k$;var Dt=p(Q()),jl=p(Xe()),zA=p(be()),pP=p(U()),gP=p(Y());var hP=p(Ut());bo();function Rx(e,t="",r=5e3){let n=[e];for(;n.length;){let o=n.pop();for(let[i,s]of Object.entries(o)){if(t.length>r)return Zh(t);typeof s=="object"&&s!==null?n.push(s):i==="locationType"&&s==="FileHandleLocation"?t+=`${i}-BlobLocation`:i==="handleId"?t+=`blobId-fh-blob-${s}`:t+=`${i}-${s}`}}return`adp-${Zh(t)}`}function aP(e={}){return e.type&&e.adapterId?`${e.type}-${e.adapterId}`:`${Rx(e)}`}var cP={};async function D$(e,t,r){let n=r?.type;if(!n)throw new Error(`could not determine adapter type from adapter config snapshot ${JSON.stringify(r)}`);let o=e.getAdapterType(n);if(!o)throw new Error(`unknown data adapter type ${n}`);let i=o.configSchema.create(r,{pluginManager:e}),s=Qx.bind(null,e,t),a=await o.getAdapterClass();return{dataAdapter:new a(i,s,e),sessionIds:new Set([t])}}async function Qx(e,t,r){let n=aP(r);cP[n]??=D$(e,t,r);let o=await cP[n];return o.sessionIds.add(t),o}async function lP(e,t){return(await Qx(e,"msa",t)).dataAdapter}async function uP({config:e,pluginManager:t}){return(await lP(t,e)).getMSAList()}async function fP({config:e,pluginManager:t,msaId:r}){return(await lP(t,e)).getMSA(r)}var dP=p(be());function AP({newViewTitle:e,view:t,feature:r,data:n,querySeqName:o}){(0,dP.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,treeAreaWidth:200,querySeqName:o,treeWidth:100,drawNodeBubbles:!1,labelsAlignRight:!0,showBranchLen:!1,colWidth:10,rowHeight:12,colorSchemeName:"percent_identity_dynamic",data:n,connectedViewId:t.id,connectedFeature:r.toJSON()})}var mP=p(ss());function qA(e){return(0,mP.readConfObject)(e,["msa","datasets"])}var N$=(0,hP.makeStyles)()({selectedContainer:{marginTop:50}}),L$=(0,gP.observer)(function({model:e,feature:t,handleClose:r}){let n=(0,zA.getSession)(e),o=Rr(e),{classes:i}=N$(),{pluginManager:s}=(0,zA.getEnv)(e),{assemblyNames:a}=o,[c,l]=(0,Dt.useState)(),u=qA(n.jbrowse),[d,A]=(0,Dt.useState)(u?.[0]?.datasetId),f=u?.find(R=>R.datasetId===d),{data:g,isLoading:h,error:x}=$i(f?`${f.datasetId}-msa-list`:null,()=>uP({config:f.adapter,pluginManager:s}),Wi),w=Rn({feature:t,view:o,validIds:g}),{selectedId:y,selectedTranscript:v}=w,{data:b,isLoading:I,error:S}=$i(y&&f&&g?`${f.datasetId}-${y}-msa`:null,()=>fP({msaId:y,config:f.adapter,pluginManager:s}),Wi),B=x??S??w.error??c;return Dt.default.createElement(Dt.default.Fragment,null,Dt.default.createElement(Xr,{error:B},Dt.default.createElement(gt,{select:!0,label:"Select MSA dataset",value:d,onChange:R=>{A(R.target.value)}},u?.map(R=>Dt.default.createElement(pP.MenuItem,{key:R.datasetId,value:R.datasetId},R.name))),f?Dt.default.createElement("div",{className:i.selectedContainer},!h&&I?Dt.default.createElement(jl.LoadingEllipses,{variant:"h6",message:`Loading MSA for (${y})`}):null,h?Dt.default.createElement(jl.LoadingEllipses,{variant:"h6",message:`Loading available MSAs for (${f.name})`}):null,g?Dt.default.createElement("div",null,Dt.default.createElement(jl.SanitizedHTML,{html:f.description}),Dt.default.createElement(en,{feature:t,...w})):null):null),Dt.default.createElement(oo,{submitDisabled:!v||!b?.length,onSubmit:()=>{try{if(v&&b){let R=`${y}_${a[0]}`;AP({newViewTitle:no(v),view:o,querySeqName:R,feature:v,data:{msa:b.map(D=>`>${D.get("refName")}
 ${D.get("seq")}`).join(`
-`)}}),r()}}catch(R){l(R)}},onCancel:r}))}),tF=f$;var rF=p(Q());function Ua({children:e,value:t,index:r,...n}){return rF.default.createElement("div",{role:"tabpanel",hidden:t!==r,...n},t===r?e:null)}function yx({handleClose:e,feature:t,model:r}){let n=(0,oF.getSession)(r),i=!!UA(n.jbrowse)?.length,[s,a]=(0,wt.useState)("orthologs");return wt.default.createElement(nF.Dialog,{maxWidth:"xl",title:"Launch MSA view",open:!0,onClose:e},wt.default.createElement(zi.Tabs,{value:s,onChange:(c,l)=>{a(l)}},wt.default.createElement(zi.Tab,{label:"Orthologs (fast)",value:"orthologs"}),wt.default.createElement(zi.Tab,{label:"NCBI BLAST query",value:"ncbi_blast"}),i?wt.default.createElement(zi.Tab,{label:"Pre-loaded MSA datasets",value:"preloaded_msa"}):null,wt.default.createElement(zi.Tab,{label:"Manual upload",value:"manual_msa"})),wt.default.createElement(Ua,{value:s,index:"orthologs"},wt.default.createElement(VP,{handleClose:e,feature:t,model:r})),wt.default.createElement(Ua,{value:s,index:"ncbi_blast"},wt.default.createElement(px,{handleClose:e,feature:t,model:r})),i?wt.default.createElement(Ua,{value:s,index:"preloaded_msa"},wt.default.createElement(tF,{model:r,feature:t,handleClose:e})):null,wt.default.createElement(Ua,{value:s,index:"manual_msa"},wt.default.createElement(iP,{model:r,feature:t,handleClose:e})))}function d$(e){return e.name==="LinearBasicDisplay"}var A$=new Set(["gene","mRNA","transcript"]);function m$(e){return e.views(t=>{let r=t.contextMenuItems;return{contextMenuItems(){let n=(0,VA.getContainingTrack)(t),o=(0,VA.getSession)(n),i=u=>{o.queueDialog(d=>[yx,{model:n,handleClose:d,feature:u}])},s=t.contextMenuInfo,a=t.fetchFullFeature,c=t.contextMenuFeature,l=s&&a&&t.isGeneLike?()=>{a(s.item.featureId,s.displayedRegionIndex).then(u=>{u?i(u):o.notify("Could not load feature for MSA view","warning")}).catch(u=>{o.notifyError(`${u}`,u)})}:c&&A$.has(String(c.get("type")))?()=>{i(c)}:void 0;return[...r(),...l?[{label:"Launch MSA view",icon:yL,onClick:l}]:[]]}}})}function xx(e){e.addToExtensionPoint("Core-extendPluggableElement",t=>(d$(t)&&(t.stateModel=m$(t.stateModel)),t))}function Cx(e){e.addToExtensionPoint("LaunchView-MsaView",t=>{let{session:r,data:n,msaFileLocation:o,msaIndexedLocation:i,msaName:s,treeFileLocation:a,querySeqName:c,...l}=t;if(!n&&!o&&!i&&!l.orthologParams)throw new Error("No MSA data, file location or orthologParams provided when launching MSA view");return r.addView("MsaView",{type:"MsaView",...l,data:n,...a?{treeFilehandle:{...a,locationType:"UriLocation"}}:{},init:{msaUrl:o?.uri,msaIndexedLocation:i,msaName:s,querySeqName:c}}),t})}var bF=p(Q()),EF=p(sF());var E$=(0,bF.lazy)(()=>Promise.resolve().then(()=>(CF(),xF)));function Ix(e){e.addViewType(()=>new EF.default({name:"MsaView",stateModel:Ly(),ReactComponent:E$}))}var wF="2.8.2";var WA=class extends IF.default{constructor(){super(...arguments);this.name="MsaViewPlugin";this.version=wF;this.rootConfigurationSchema=r=>({msa:(0,Sx.ConfigurationSchema)("MSA",{datasets:vx.types.maybe(vx.types.array((0,Sx.ConfigurationSchema)("MSAEntry",{datasetId:{type:"string",defaultValue:""},description:{type:"string",defaultValue:""},name:{type:"string",defaultValue:""},adapter:r.pluggableConfigSchemaType("adapter")})))})})}install(r){Ix(r),xx(r),Cx(r),Gy(r),Hy(r)}configure(r){(0,SF.isAbstractMenuManager)(r.rootModel)&&r.rootModel.appendToSubMenu(["Add"],{label:"Multiple sequence alignment view",icon:Dw,onClick:n=>{n.addView("MsaView",{})}})}};return YF(w$);})();
+`)}}),r()}}catch(R){l(R)}},onCancel:r}))}),yP=L$;var xP=p(Q());function ja({children:e,value:t,index:r,...n}){return xP.default.createElement("div",{role:"tabpanel",hidden:t!==r,...n},t===r?e:null)}function _x({handleClose:e,feature:t,model:r}){let n=(0,EP.getSession)(r),i=!!qA(n.jbrowse)?.length,[s,a]=(0,wt.useState)("orthologs");return wt.default.createElement(CP.Dialog,{maxWidth:"xl",title:"Launch MSA view",open:!0,onClose:e},wt.default.createElement(qi.Tabs,{value:s,onChange:(c,l)=>{a(l)}},wt.default.createElement(qi.Tab,{label:"Orthologs (fast)",value:"orthologs"}),wt.default.createElement(qi.Tab,{label:"BLAST query",value:"ncbi_blast"}),i?wt.default.createElement(qi.Tab,{label:"Pre-loaded MSA datasets",value:"preloaded_msa"}):null,wt.default.createElement(qi.Tab,{label:"Manual upload",value:"manual_msa"})),wt.default.createElement(ja,{value:s,index:"orthologs"},wt.default.createElement(sP,{handleClose:e,feature:t,model:r})),wt.default.createElement(ja,{value:s,index:"ncbi_blast"},wt.default.createElement(Bx,{handleClose:e,feature:t,model:r})),i?wt.default.createElement(ja,{value:s,index:"preloaded_msa"},wt.default.createElement(yP,{model:r,feature:t,handleClose:e})):null,wt.default.createElement(ja,{value:s,index:"manual_msa"},wt.default.createElement(ZF,{model:r,feature:t,handleClose:e})))}function F$(e){return e.name==="LinearBasicDisplay"}function P$(e){let t=(e??"").toLowerCase();return t.includes("gene")||t.includes("rna")||t.includes("transcript")}var O$=new Set(["gene","mRNA","transcript"]);function G$(e){return e.views(t=>{let r=t.contextMenuItems;return{contextMenuItems(){let n=(0,JA.getContainingTrack)(t),o=(0,JA.getSession)(n),i=u=>{o.queueDialog(d=>[_x,{model:n,handleClose:d,feature:u}])},s=t.contextMenuInfo,a=t.fetchFullFeature,c=t.contextMenuFeature,l=s&&a&&P$(s.item.type)?()=>{a(s.item.featureId,s.displayedRegionIndex).then(u=>{u?i(u):o.notify("Could not load feature for MSA view","warning")}).catch(u=>{o.notifyError(`${u}`,u)})}:c&&O$.has(String(c.get("type")))?()=>{i(c)}:void 0;return[...r(),...l?[{label:"Launch MSA view",icon:FL,onClick:l}]:[]]}}})}function kx(e){e.addToExtensionPoint("Core-extendPluggableElement",t=>(F$(t)&&(t.stateModel=G$(t.stateModel)),t))}function Dx(e){e.addToExtensionPoint("LaunchView-MsaView",t=>{let{session:r,data:n,msaFileLocation:o,msaIndexedLocation:i,msaName:s,treeFileLocation:a,querySeqName:c,...l}=t;if(!n&&!o&&!i&&!l.orthologParams)throw new Error("No MSA data, file location or orthologParams provided when launching MSA view");return r.addView("MsaView",{type:"MsaView",...l,data:n,...a?{treeFilehandle:{...a,locationType:"UriLocation"}}:{},init:{msaUrl:o?.uri,msaIndexedLocation:i,msaName:s,querySeqName:c}}),t})}var FP=p(Q()),PP=p(wP());var Y$=(0,FP.lazy)(()=>Promise.resolve().then(()=>(LP(),NP)));function Px(e){e.addViewType(()=>new PP.default({name:"MsaView",stateModel:Yy(),ReactComponent:Y$}))}var OP="2.10.0";var ZA=class extends GP.default{constructor(){super(...arguments);this.name="MsaViewPlugin";this.version=OP;this.rootConfigurationSchema=r=>({msa:(0,Ox.ConfigurationSchema)("MSA",{datasets:Gx.types.maybe(Gx.types.array((0,Ox.ConfigurationSchema)("MSAEntry",{datasetId:{type:"string",defaultValue:""},description:{type:"string",defaultValue:""},name:{type:"string",defaultValue:""},adapter:r.pluggableConfigSchemaType("adapter")})))})})}install(r){Px(r),kx(r),Dx(r),Ky(r),Zy(r)}configure(r){(0,UP.isAbstractMenuManager)(r.rootModel)&&r.rootModel.appendToSubMenu(["Add"],{label:"Multiple sequence alignment view",icon:qw,onClick:n=>{n.addView("MsaView",{})}})}};return lO(q$);})();
 /*! Bundled license information:
 
 react-is/cjs/react-is.production.js: