jbrowse-plugin-msaview 2.7.3 → 2.7.4

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Files changed (29) hide show
  1. package/dist/LaunchMsaView/components/LaunchMsaViewDialog.js +7 -1
  2. package/dist/LaunchMsaView/components/OrthologQuery/OrthologPanel.d.ts +8 -0
  3. package/dist/LaunchMsaView/components/OrthologQuery/OrthologPanel.js +86 -0
  4. package/dist/LaunchMsaView/components/OrthologQuery/orthologLaunchView.d.ts +9 -0
  5. package/dist/LaunchMsaView/components/OrthologQuery/orthologLaunchView.js +13 -0
  6. package/dist/MsaViewPanel/afterCreateAutoruns.d.ts +8 -0
  7. package/dist/MsaViewPanel/afterCreateAutoruns.js +28 -0
  8. package/dist/MsaViewPanel/doLaunchOrthologs.d.ts +23 -0
  9. package/dist/MsaViewPanel/doLaunchOrthologs.js +97 -0
  10. package/dist/MsaViewPanel/model.d.ts +21 -5
  11. package/dist/MsaViewPanel/model.js +12 -1
  12. package/dist/jbrowse-plugin-msaview.umd.production.min.js +31 -27
  13. package/dist/jbrowse-plugin-msaview.umd.production.min.js.map +4 -4
  14. package/dist/utils/ncbiOrthologs.d.ts +105 -0
  15. package/dist/utils/ncbiOrthologs.js +211 -0
  16. package/dist/utils/ncbiOrthologs.test.d.ts +1 -0
  17. package/dist/utils/ncbiOrthologs.test.js +41 -0
  18. package/dist/version.d.ts +1 -1
  19. package/dist/version.js +1 -1
  20. package/package.json +3 -3
  21. package/src/LaunchMsaView/components/LaunchMsaViewDialog.tsx +13 -2
  22. package/src/LaunchMsaView/components/OrthologQuery/OrthologPanel.tsx +172 -0
  23. package/src/LaunchMsaView/components/OrthologQuery/orthologLaunchView.ts +28 -0
  24. package/src/MsaViewPanel/afterCreateAutoruns.ts +27 -0
  25. package/src/MsaViewPanel/doLaunchOrthologs.ts +123 -0
  26. package/src/MsaViewPanel/model.ts +24 -0
  27. package/src/utils/ncbiOrthologs.test.ts +56 -0
  28. package/src/utils/ncbiOrthologs.ts +320 -0
  29. package/src/version.ts +1 -1
package/dist/jbrowse-plugin-msaview.umd.production.min.js CHANGED
@@ -1,4 +1,4 @@
1
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2
2
 
3
3
  const theme = ${JSON.stringify(t,null,2)};
4
4
 
@@ -6,15 +6,15 @@ theme.breakpoints = createBreakpoints(theme.breakpoints || {});
6
6
  theme.motion = { reducedMotion: 'never', ...theme.motion };
7
7
  theme.transitions = createTransitions(theme.transitions || {});
8
8
 
9
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10
- To suppress this warning, you need to explicitly provide the \`palette.${t}Channel\` as a string (in rgb format, for example "12 12 12") or undefined if you want to remove the channel token.`))}function q3(e){return typeof e=="number"?`${e}px`:typeof e=="string"||typeof e=="function"||Array.isArray(e)?e:"8px"}function Sp(e,t,r,n,o){if(!r)return;r=r===!0?{}:r;let i=o==="dark"?"dark":"light";if(!n){t[o]=wp({...r,palette:{mode:i,...r?.palette},colorSpace:e});return}let{palette:s,...a}=Ac({...n,palette:{mode:i,...r?.palette},colorSpace:e});return t[o]={...r,palette:s,opacity:{...Ep(i),...r?.opacity},overlays:r?.overlays||bp(i)},a}function vp(e={},...t){let{colorSchemes:r={light:!0},defaultColorScheme:n,disableCssColorScheme:o=!1,cssVarPrefix:i="mui",nativeColor:s=!1,shouldSkipGeneratingVar:a=Ip,colorSchemeSelector:c=r.light&&r.dark?"media":void 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n=t;this._sourceRoot!=null&&(n=qe.relative(this._sourceRoot,n)),r!=null?(this._sourcesContents||(this._sourcesContents=Object.create(null)),this._sourcesContents[qe.toSetString(n)]=r):this._sourcesContents&&(delete this._sourcesContents[qe.toSetString(n)],Object.keys(this._sourcesContents).length===0&&(this._sourcesContents=null))};wr.prototype.applySourceMap=function(t,r,n){var o=r;if(r==null){if(t.file==null)throw new Error(`SourceMapGenerator.prototype.applySourceMap requires either an explicit source file, or the source map's "file" property. Both were omitted.`);o=t.file}var i=this._sourceRoot;i!=null&&(o=qe.relative(i,o));var s=new pf,a=new pf;this._mappings.unsortedForEach(function(c){if(c.source===o&&c.originalLine!=null){var l=t.originalPositionFor({line:c.originalLine,column:c.originalColumn});l.source!=null&&(c.source=l.source,n!=null&&(c.source=qe.join(n,c.source)),i!=null&&(c.source=qe.relative(i,c.source)),c.originalLine=l.line,c.originalColumn=l.column,l.name!=null&&(c.name=l.name))}var u=c.source;u!=null&&!s.has(u)&&s.add(u);var d=c.name;d!=null&&!a.has(d)&&a.add(d)},this),this._sources=s,this._names=a,t.sources.forEach(function(c){var l=t.sourceContentFor(c);l!=null&&(n!=null&&(c=qe.join(n,c)),i!=null&&(c=qe.relative(i,c)),this.setSourceContent(c,l))},this)};wr.prototype._validateMapping=function(t,r,n,o){if(r&&typeof r.line!="number"&&typeof r.column!="number"){var i="original.line and original.column are not numbers -- you probably meant to omit the original mapping entirely and only map the generated position. If so, pass null for the original mapping instead of an object with empty or null values.";if(this._ignoreInvalidMapping)return typeof console<"u"&&console.warn&&console.warn(i),!1;throw new Error(i)}if(!(t&&"line"in t&&"column"in t&&t.line>0&&t.column>=0&&!r&&!n&&!o)){if(t&&"line"in t&&"column"in t&&r&&"line"in r&&"column"in r&&t.line>0&&t.column>=0&&r.line>0&&r.column>=0&&n)return;var i="Invalid mapping: "+JSON.stringify({generated:t,source:n,original:r,name:o});if(this._ignoreInvalidMapping)return typeof console<"u"&&console.warn&&console.warn(i),!1;throw new Error(i)}};wr.prototype._serializeMappings=function(){for(var t=0,r=1,n=0,o=0,i=0,s=0,a="",c,l,u,d,A=this._mappings.toArray(),f=0,g=A.length;f<g;f++){if(l=A[f],c="",l.generatedLine!==r)for(t=0;l.generatedLine!==r;)c+=";",r++;else if(f>0){if(!qe.compareByGeneratedPositionsInflated(l,A[f-1]))continue;c+=","}c+=Rc.encode(l.generatedColumn-t),t=l.generatedColumn,l.source!=null&&(d=this._sources.indexOf(l.source),c+=Rc.encode(d-s),s=d,c+=Rc.encode(l.originalLine-1-o),o=l.originalLine-1,c+=Rc.encode(l.originalColumn-n),n=l.originalColumn,l.name!=null&&(u=this._names.indexOf(l.name),c+=Rc.encode(u-i),i=u)),a+=c}return a};wr.prototype._generateSourcesContent=function(t,r){return t.map(function(n){if(!this._sourcesContents)return null;r!=null&&(n=qe.relative(r,n));var o=qe.toSetString(n);return Object.prototype.hasOwnProperty.call(this._sourcesContents,o)?this._sourcesContents[o]:null},this)};wr.prototype.toJSON=function(){var t={version:this._version,sources:this._sources.toArray(),names:this._names.toArray(),mappings:this._serializeMappings()};return this._file!=null&&(t.file=this._file),this._sourceRoot!=null&&(t.sourceRoot=this._sourceRoot),this._sourcesContents&&(t.sourcesContent=this._generateSourcesContent(t.sources,t.sourceRoot)),t};wr.prototype.toString=function(){return JSON.stringify(this.toJSON())};e1.SourceMapGenerator=wr});var t1=K(gi=>{gi.GREATEST_LOWER_BOUND=1;gi.LEAST_UPPER_BOUND=2;function Tg(e,t,r,n,o,i){var s=Math.floor((t-e)/2)+e,a=o(r,n[s],!0);return a===0?s:a>0?t-s>1?Tg(s,t,r,n,o,i):i==gi.LEAST_UPPER_BOUND?t<n.length?t:-1:s:s-e>1?Tg(e,s,r,n,o,i):i==gi.LEAST_UPPER_BOUND?s:e<0?-1:e}gi.search=function(t,r,n,o){if(r.length===0)return-1;var i=Tg(-1,r.length,t,r,n,o||gi.GREATEST_LOWER_BOUND);if(i<0)return-1;for(;i-1>=0&&n(r[i],r[i-1],!0)===0;)--i;return i}});var o1=K(n1=>{function xG(e){function t(o,i,s){var a=o[i];o[i]=o[s],o[s]=a}function r(o,i){return Math.round(o+Math.random()*(i-o))}function n(o,i,s,a){if(s<a){var c=r(s,a),l=s-1;t(o,c,a);for(var u=o[a],d=s;d<a;d++)i(o[d],u,!1)<=0&&(l+=1,t(o,l,d));t(o,l+1,d);var A=l+1;n(o,i,s,A-1),n(o,i,A+1,a)}}return n}function CG(e){let t=xG.toString();return new Function(`return ${t}`)()(e)}var r1=new WeakMap;n1.quickSort=function(e,t,r=0){let n=r1.get(t);n===void 0&&(n=CG(t),r1.set(t,n)),n(e,t,r,e.length-1)}});var a1=K(gf=>{var H=Vs(),Rg=t1(),js=vg().ArraySet,EG=bg(),Qc=o1().quickSort;function Re(e,t){var r=e;return typeof e=="string"&&(r=H.parseSourceMapInput(e)),r.sections!=null?new jr(r,t):new gt(r,t)}Re.fromSourceMap=function(e,t){return gt.fromSourceMap(e,t)};Re.prototype._version=3;Re.prototype.__generatedMappings=null;Object.defineProperty(Re.prototype,"_generatedMappings",{configurable:!0,enumerable:!0,get:function(){return this.__generatedMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__generatedMappings}});Re.prototype.__originalMappings=null;Object.defineProperty(Re.prototype,"_originalMappings",{configurable:!0,enumerable:!0,get:function(){return this.__originalMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__originalMappings}});Re.prototype._charIsMappingSeparator=function(t,r){var n=t.charAt(r);return n===";"||n===","};Re.prototype._parseMappings=function(t,r){throw new Error("Subclasses must implement _parseMappings")};Re.GENERATED_ORDER=1;Re.ORIGINAL_ORDER=2;Re.GREATEST_LOWER_BOUND=1;Re.LEAST_UPPER_BOUND=2;Re.prototype.eachMapping=function(t,r,n){var o=r||null,i=n||Re.GENERATED_ORDER,s;switch(i){case Re.GENERATED_ORDER:s=this._generatedMappings;break;case Re.ORIGINAL_ORDER:s=this._originalMappings;break;default:throw new Error("Unknown order of iteration.")}for(var a=this.sourceRoot,c=t.bind(o),l=this._names,u=this._sources,d=this._sourceMapURL,A=0,f=s.length;A<f;A++){var g=s[A],h=g.source===null?null:u.at(g.source);h!==null&&(h=H.computeSourceURL(a,h,d)),c({source:h,generatedLine:g.generatedLine,generatedColumn:g.generatedColumn,originalLine:g.originalLine,originalColumn:g.originalColumn,name:g.name===null?null:l.at(g.name)})}};Re.prototype.allGeneratedPositionsFor=function(t){var r=H.getArg(t,"line"),n={source:H.getArg(t,"source"),originalLine:r,originalColumn:H.getArg(t,"column",0)};if(n.source=this._findSourceIndex(n.source),n.source<0)return[];var o=[],i=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",H.compareByOriginalPositions,Rg.LEAST_UPPER_BOUND);if(i>=0){var s=this._originalMappings[i];if(t.column===void 0)for(var a=s.originalLine;s&&s.originalLine===a;)o.push({line:H.getArg(s,"generatedLine",null),column:H.getArg(s,"generatedColumn",null),lastColumn:H.getArg(s,"lastGeneratedColumn",null)}),s=this._originalMappings[++i];else for(var c=s.originalColumn;s&&s.originalLine===r&&s.originalColumn==c;)o.push({line:H.getArg(s,"generatedLine",null),column:H.getArg(s,"generatedColumn",null),lastColumn:H.getArg(s,"lastGeneratedColumn",null)}),s=this._originalMappings[++i]}return o};gf.SourceMapConsumer=Re;function gt(e,t){var r=e;typeof e=="string"&&(r=H.parseSourceMapInput(e));var n=H.getArg(r,"version"),o=H.getArg(r,"sources"),i=H.getArg(r,"names",[]),s=H.getArg(r,"sourceRoot",null),a=H.getArg(r,"sourcesContent",null),c=H.getArg(r,"mappings"),l=H.getArg(r,"file",null);if(n!=this._version)throw new Error("Unsupported version: "+n);s&&(s=H.normalize(s)),o=o.map(String).map(H.normalize).map(function(u){return s&&H.isAbsolute(s)&&H.isAbsolute(u)?H.relative(s,u):u}),this._names=js.fromArray(i.map(String),!0),this._sources=js.fromArray(o,!0),this._absoluteSources=this._sources.toArray().map(function(u){return H.computeSourceURL(s,u,t)}),this.sourceRoot=s,this.sourcesContent=a,this._mappings=c,this._sourceMapURL=t,this.file=l}gt.prototype=Object.create(Re.prototype);gt.prototype.consumer=Re;gt.prototype._findSourceIndex=function(e){var t=e;if(this.sourceRoot!=null&&(t=H.relative(this.sourceRoot,t)),this._sources.has(t))return this._sources.indexOf(t);var r;for(r=0;r<this._absoluteSources.length;++r)if(this._absoluteSources[r]==e)return r;return-1};gt.fromSourceMap=function(t,r){var n=Object.create(gt.prototype),o=n._names=js.fromArray(t._names.toArray(),!0),i=n._sources=js.fromArray(t._sources.toArray(),!0);n.sourceRoot=t._sourceRoot,n.sourcesContent=t._generateSourcesContent(n._sources.toArray(),n.sourceRoot),n.file=t._file,n._sourceMapURL=r,n._absoluteSources=n._sources.toArray().map(function(f){return H.computeSourceURL(n.sourceRoot,f,r)});for(var s=t._mappings.toArray().slice(),a=n.__generatedMappings=[],c=n.__originalMappings=[],l=0,u=s.length;l<u;l++){var d=s[l],A=new s1;A.generatedLine=d.generatedLine,A.generatedColumn=d.generatedColumn,d.source&&(A.source=i.indexOf(d.source),A.originalLine=d.originalLine,A.originalColumn=d.originalColumn,d.name&&(A.name=o.indexOf(d.name)),c.push(A)),a.push(A)}return Qc(n.__originalMappings,H.compareByOriginalPositions),n};gt.prototype._version=3;Object.defineProperty(gt.prototype,"sources",{get:function(){return this._absoluteSources.slice()}});function s1(){this.generatedLine=0,this.generatedColumn=0,this.source=null,this.originalLine=null,this.originalColumn=null,this.name=null}var Mg=H.compareByGeneratedPositionsDeflatedNoLine;function i1(e,t){let r=e.length,n=e.length-t;if(!(n<=1))if(n==2){let o=e[t],i=e[t+1];Mg(o,i)>0&&(e[t]=i,e[t+1]=o)}else if(n<20)for(let o=t;o<r;o++)for(let i=o;i>t;i--){let s=e[i-1],a=e[i];if(Mg(s,a)<=0)break;e[i-1]=a,e[i]=s}else Qc(e,Mg,t)}gt.prototype._parseMappings=function(t,r){var n=1,o=0,i=0,s=0,a=0,c=0,l=t.length,u=0,d={},A={},f=[],g=[],h,y,b,x,v;let w=0;for(;u<l;)if(t.charAt(u)===";")n++,u++,o=0,i1(g,w),w=g.length;else if(t.charAt(u)===",")u++;else{for(h=new s1,h.generatedLine=n,x=u;x<l&&!this._charIsMappingSeparator(t,x);x++);for(y=t.slice(u,x),b=[];u<x;)EG.decode(t,u,A),v=A.value,u=A.rest,b.push(v);if(b.length===2)throw new Error("Found a source, but no line and column");if(b.length===3)throw new Error("Found a source and line, but no column");if(h.generatedColumn=o+b[0],o=h.generatedColumn,b.length>1&&(h.source=a+b[1],a+=b[1],h.originalLine=i+b[2],i=h.originalLine,h.originalLine+=1,h.originalColumn=s+b[3],s=h.originalColumn,b.length>4&&(h.name=c+b[4],c+=b[4])),g.push(h),typeof h.originalLine=="number"){let S=h.source;for(;f.length<=S;)f.push(null);f[S]===null&&(f[S]=[]),f[S].push(h)}}i1(g,w),this.__generatedMappings=g;for(var I=0;I<f.length;I++)f[I]!=null&&Qc(f[I],H.compareByOriginalPositionsNoSource);this.__originalMappings=[].concat(...f)};gt.prototype._findMapping=function(t,r,n,o,i,s){if(t[n]<=0)throw new TypeError("Line must be greater than or equal to 1, got "+t[n]);if(t[o]<0)throw new TypeError("Column must be greater than or equal to 0, got "+t[o]);return Rg.search(t,r,i,s)};gt.prototype.computeColumnSpans=function(){for(var t=0;t<this._generatedMappings.length;++t){var r=this._generatedMappings[t];if(t+1<this._generatedMappings.length){var n=this._generatedMappings[t+1];if(r.generatedLine===n.generatedLine){r.lastGeneratedColumn=n.generatedColumn-1;continue}}r.lastGeneratedColumn=1/0}};gt.prototype.originalPositionFor=function(t){var r={generatedLine:H.getArg(t,"line"),generatedColumn:H.getArg(t,"column")},n=this._findMapping(r,this._generatedMappings,"generatedLine","generatedColumn",H.compareByGeneratedPositionsDeflated,H.getArg(t,"bias",Re.GREATEST_LOWER_BOUND));if(n>=0){var o=this._generatedMappings[n];if(o.generatedLine===r.generatedLine){var i=H.getArg(o,"source",null);i!==null&&(i=this._sources.at(i),i=H.computeSourceURL(this.sourceRoot,i,this._sourceMapURL));var s=H.getArg(o,"name",null);return s!==null&&(s=this._names.at(s)),{source:i,line:H.getArg(o,"originalLine",null),column:H.getArg(o,"originalColumn",null),name:s}}}return{source:null,line:null,column:null,name:null}};gt.prototype.hasContentsOfAllSources=function(){return this.sourcesContent?this.sourcesContent.length>=this._sources.size()&&!this.sourcesContent.some(function(t){return t==null}):!1};gt.prototype.sourceContentFor=function(t,r){if(!this.sourcesContent)return null;var n=this._findSourceIndex(t);if(n>=0)return this.sourcesContent[n];var o=t;this.sourceRoot!=null&&(o=H.relative(this.sourceRoot,o));var i;if(this.sourceRoot!=null&&(i=H.urlParse(this.sourceRoot))){var s=o.replace(/^file:\/\//,"");if(i.scheme=="file"&&this._sources.has(s))return this.sourcesContent[this._sources.indexOf(s)];if((!i.path||i.path=="/")&&this._sources.has("/"+o))return this.sourcesContent[this._sources.indexOf("/"+o)]}if(r)return null;throw new Error('"'+o+'" is not in the SourceMap.')};gt.prototype.generatedPositionFor=function(t){var r=H.getArg(t,"source");if(r=this._findSourceIndex(r),r<0)return{line:null,column:null,lastColumn:null};var n={source:r,originalLine:H.getArg(t,"line"),originalColumn:H.getArg(t,"column")},o=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",H.compareByOriginalPositions,H.getArg(t,"bias",Re.GREATEST_LOWER_BOUND));if(o>=0){var i=this._originalMappings[o];if(i.source===n.source)return{line:H.getArg(i,"generatedLine",null),column:H.getArg(i,"generatedColumn",null),lastColumn:H.getArg(i,"lastGeneratedColumn",null)}}return{line:null,column:null,lastColumn:null}};gf.BasicSourceMapConsumer=gt;function jr(e,t){var r=e;typeof e=="string"&&(r=H.parseSourceMapInput(e));var n=H.getArg(r,"version"),o=H.getArg(r,"sections");if(n!=this._version)throw new Error("Unsupported version: "+n);this._sources=new js,this._names=new js;var i={line:-1,column:0};this._sections=o.map(function(s){if(s.url)throw new Error("Support for url field in sections not implemented.");var a=H.getArg(s,"offset"),c=H.getArg(a,"line"),l=H.getArg(a,"column");if(c<i.line||c===i.line&&l<i.column)throw new Error("Section offsets must be ordered and non-overlapping.");return i=a,{generatedOffset:{generatedLine:c+1,generatedColumn:l+1},consumer:new Re(H.getArg(s,"map"),t)}})}jr.prototype=Object.create(Re.prototype);jr.prototype.constructor=Re;jr.prototype._version=3;Object.defineProperty(jr.prototype,"sources",{get:function(){for(var e=[],t=0;t<this._sections.length;t++)for(var r=0;r<this._sections[t].consumer.sources.length;r++)e.push(this._sections[t].consumer.sources[r]);return e}});jr.prototype.originalPositionFor=function(t){var r={generatedLine:H.getArg(t,"line"),generatedColumn:H.getArg(t,"column")},n=Rg.search(r,this._sections,function(i,s){var a=i.generatedLine-s.generatedOffset.generatedLine;return a||i.generatedColumn-s.generatedOffset.generatedColumn}),o=this._sections[n];return o?o.consumer.originalPositionFor({line:r.generatedLine-(o.generatedOffset.generatedLine-1),column:r.generatedColumn-(o.generatedOffset.generatedLine===r.generatedLine?o.generatedOffset.generatedColumn-1:0),bias:t.bias}):{source:null,line:null,column:null,name:null}};jr.prototype.hasContentsOfAllSources=function(){return this._sections.every(function(t){return t.consumer.hasContentsOfAllSources()})};jr.prototype.sourceContentFor=function(t,r){for(var n=0;n<this._sections.length;n++){var o=this._sections[n],i=o.consumer.sourceContentFor(t,!0);if(i||i==="")return i}if(r)return null;throw new Error('"'+t+'" is not in the SourceMap.')};jr.prototype.generatedPositionFor=function(t){for(var r=0;r<this._sections.length;r++){var n=this._sections[r];if(n.consumer._findSourceIndex(H.getArg(t,"source"))!==-1){var o=n.consumer.generatedPositionFor(t);if(o){var i={line:o.line+(n.generatedOffset.generatedLine-1),column:o.column+(n.generatedOffset.generatedLine===o.line?n.generatedOffset.generatedColumn-1:0)};return i}}}return{line:null,column:null}};jr.prototype._parseMappings=function(t,r){this.__generatedMappings=[],this.__originalMappings=[];for(var n=0;n<this._sections.length;n++)for(var o=this._sections[n],i=o.consumer._generatedMappings,s=0;s<i.length;s++){var a=i[s],c=o.consumer._sources.at(a.source);c!==null&&(c=H.computeSourceURL(o.consumer.sourceRoot,c,this._sourceMapURL)),this._sources.add(c),c=this._sources.indexOf(c);var l=null;a.name&&(l=o.consumer._names.at(a.name),this._names.add(l),l=this._names.indexOf(l));var u={source:c,generatedLine:a.generatedLine+(o.generatedOffset.generatedLine-1),generatedColumn:a.generatedColumn+(o.generatedOffset.generatedLine===a.generatedLine?o.generatedOffset.generatedColumn-1:0),originalLine:a.originalLine,originalColumn:a.originalColumn,name:l};this.__generatedMappings.push(u),typeof u.originalLine=="number"&&this.__originalMappings.push(u)}Qc(this.__generatedMappings,H.compareByGeneratedPositionsDeflated),Qc(this.__originalMappings,H.compareByOriginalPositions)};gf.IndexedSourceMapConsumer=jr});var l1=K(c1=>{var bG=Bg().SourceMapGenerator,hf=Vs(),wG=/(\r?\n)/,IG=10,$s="$$$isSourceNode$$$";function or(e,t,r,n,o){this.children=[],this.sourceContents={},this.line=e??null,this.column=t??null,this.source=r??null,this.name=o??null,this[$s]=!0,n!=null&&this.add(n)}or.fromStringWithSourceMap=function(t,r,n){var o=new or,i=t.split(wG),s=0,a=function(){var A=g(),f=g()||"";return A+f;function g(){return s<i.length?i[s++]:void 0}},c=1,l=0,u=null;return r.eachMapping(function(A){if(u!==null)if(c<A.generatedLine)d(u,a()),c++,l=0;else{var f=i[s]||"",g=f.substr(0,A.generatedColumn-l);i[s]=f.substr(A.generatedColumn-l),l=A.generatedColumn,d(u,g),u=A;return}for(;c<A.generatedLine;)o.add(a()),c++;if(l<A.generatedColumn){var f=i[s]||"";o.add(f.substr(0,A.generatedColumn)),i[s]=f.substr(A.generatedColumn),l=A.generatedColumn}u=A},this),s<i.length&&(u&&d(u,a()),o.add(i.splice(s).join(""))),r.sources.forEach(function(A){var f=r.sourceContentFor(A);f!=null&&(n!=null&&(A=hf.join(n,A)),o.setSourceContent(A,f))}),o;function d(A,f){if(A===null||A.source===void 0)o.add(f);else{var g=n?hf.join(n,A.source):A.source;o.add(new or(A.originalLine,A.originalColumn,g,f,A.name))}}};or.prototype.add=function(t){if(Array.isArray(t))t.forEach(function(r){this.add(r)},this);else if(t[$s]||typeof t=="string")t&&this.children.push(t);else throw new TypeError("Expected a SourceNode, string, or an array of SourceNodes and strings. Got "+t);return this};or.prototype.prepend=function(t){if(Array.isArray(t))for(var r=t.length-1;r>=0;r--)this.prepend(t[r]);else if(t[$s]||typeof t=="string")this.children.unshift(t);else throw new TypeError("Expected a SourceNode, string, or an array of SourceNodes and strings. Got "+t);return this};or.prototype.walk=function(t){for(var r,n=0,o=this.children.length;n<o;n++)r=this.children[n],r[$s]?r.walk(t):r!==""&&t(r,{source:this.source,line:this.line,column:this.column,name:this.name})};or.prototype.join=function(t){var r,n,o=this.children.length;if(o>0){for(r=[],n=0;n<o-1;n++)r.push(this.children[n]),r.push(t);r.push(this.children[n]),this.children=r}return this};or.prototype.replaceRight=function(t,r){var n=this.children[this.children.length-1];return n[$s]?n.replaceRight(t,r):typeof n=="string"?this.children[this.children.length-1]=n.replace(t,r):this.children.push("".replace(t,r)),this};or.prototype.setSourceContent=function(t,r){this.sourceContents[hf.toSetString(t)]=r};or.prototype.walkSourceContents=function(t){for(var r=0,n=this.children.length;r<n;r++)this.children[r][$s]&&this.children[r].walkSourceContents(t);for(var o=Object.keys(this.sourceContents),r=0,n=o.length;r<n;r++)t(hf.fromSetString(o[r]),this.sourceContents[o[r]])};or.prototype.toString=function(){var t="";return this.walk(function(r){t+=r}),t};or.prototype.toStringWithSourceMap=function(t){var r={code:"",line:1,column:0},n=new bG(t),o=!1,i=null,s=null,a=null,c=null;return this.walk(function(l,u){r.code+=l,u.source!==null&&u.line!==null&&u.column!==null?((i!==u.source||s!==u.line||a!==u.column||c!==u.name)&&n.addMapping({source:u.source,original:{line:u.line,column:u.column},generated:{line:r.line,column:r.column},name:u.name}),i=u.source,s=u.line,a=u.column,c=u.name,o=!0):o&&(n.addMapping({generated:{line:r.line,column:r.column}}),i=null,o=!1);for(var d=0,A=l.length;d<A;d++)l.charCodeAt(d)===IG?(r.line++,r.column=0,d+1===A?(i=null,o=!1):o&&n.addMapping({source:u.source,original:{line:u.line,column:u.column},generated:{line:r.line,column:r.column},name:u.name})):r.column++}),this.walkSourceContents(function(l,u){n.setSourceContent(l,u)}),{code:r.code,map:n}};c1.SourceNode=or});var u1=K(yf=>{yf.SourceMapGenerator=Bg().SourceMapGenerator;yf.SourceMapConsumer=a1().SourceMapConsumer;yf.SourceNode=l1().SourceNode});var f1,d1,A1=m(()=>{"use client";nr();f1=p(O(),1),d1=(0,Me.createSvgIcon)((0,f1.jsx)("path",{d:"M19 19H5V5h7V3H5c-1.11 0-2 .9-2 2v14c0 1.1.89 2 2 2h14c1.1 0 2-.9 2-2v-7h-2zM14 3v2h3.59l-9.83 9.83 1.41 1.41L19 6.41V10h2V3z"}),"OpenInNew")});function Cf(e){let{children:t,...r}=e;return(0,xf.jsxs)(m1.Link,{...r,target:"_blank",rel:"noopener noreferrer",children:[t," ",(0,xf.jsx)(d1,{fontSize:"small"})]})}var xf,m1,p1=m(()=>{xf=p(O(),1);A1();m1=p(U(),1)});function Qg({text:e,extra:t}){let{classes:r}=SG(),n=t?`supporting data: ${JSON.stringify(t,null,2)}`:"",o=[e,n].filter(Boolean).join(`
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10
+ To suppress this warning, you need to explicitly provide the \`palette.${t}Channel\` as a string (in rgb format, for example "12 12 12") or undefined if you want to remove the channel token.`))}function p4(e){return typeof e=="number"?`${e}px`:typeof e=="string"||typeof e=="function"||Array.isArray(e)?e:"8px"}function Rp(e,t,r,n,o){if(!r)return;r=r===!0?{}:r;let i=o==="dark"?"dark":"light";if(!n){t[o]=Tp({...r,palette:{mode:i,...r?.palette},colorSpace:e});return}let{palette:s,...a}=bc({...n,palette:{mode:i,...r?.palette},colorSpace:e});return t[o]={...r,palette:s,opacity:{...vp(i),...r?.opacity},overlays:r?.overlays||Bp(i)},a}function Qp(e={},...t){let{colorSchemes:r={light:!0},defaultColorScheme:n,disableCssColorScheme:o=!1,cssVarPrefix:i="mui",nativeColor:s=!1,shouldSkipGeneratingVar:a=Mp,colorSchemeSelector:c=r.light&&r.dark?"media":void 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Both were omitted.`);o=t.file}var i=this._sourceRoot;i!=null&&(o=ze.relative(i,o));var s=new wf,a=new wf;this._mappings.unsortedForEach(function(c){if(c.source===o&&c.originalLine!=null){var l=t.originalPositionFor({line:c.originalLine,column:c.originalColumn});l.source!=null&&(c.source=l.source,n!=null&&(c.source=ze.join(n,c.source)),i!=null&&(c.source=ze.relative(i,c.source)),c.originalLine=l.line,c.originalColumn=l.column,l.name!=null&&(c.name=l.name))}var u=c.source;u!=null&&!s.has(u)&&s.add(u);var d=c.name;d!=null&&!a.has(d)&&a.add(d)},this),this._sources=s,this._names=a,t.sources.forEach(function(c){var l=t.sourceContentFor(c);l!=null&&(n!=null&&(c=ze.join(n,c)),i!=null&&(c=ze.relative(i,c)),this.setSourceContent(c,l))},this)};Tr.prototype._validateMapping=function(t,r,n,o){if(r&&typeof r.line!="number"&&typeof r.column!="number"){var i="original.line and original.column are not numbers -- you probably meant to omit the original mapping entirely and only map the generated position. If so, pass null for the original mapping instead of an object with empty or null values.";if(this._ignoreInvalidMapping)return typeof console<"u"&&console.warn&&console.warn(i),!1;throw new Error(i)}if(!(t&&"line"in t&&"column"in t&&t.line>0&&t.column>=0&&!r&&!n&&!o)){if(t&&"line"in t&&"column"in t&&r&&"line"in r&&"column"in r&&t.line>0&&t.column>=0&&r.line>0&&r.column>=0&&n)return;var i="Invalid mapping: "+JSON.stringify({generated:t,source:n,original:r,name:o});if(this._ignoreInvalidMapping)return typeof console<"u"&&console.warn&&console.warn(i),!1;throw new Error(i)}};Tr.prototype._serializeMappings=function(){for(var t=0,r=1,n=0,o=0,i=0,s=0,a="",c,l,u,d,A=this._mappings.toArray(),f=0,g=A.length;f<g;f++){if(l=A[f],c="",l.generatedLine!==r)for(t=0;l.generatedLine!==r;)c+=";",r++;else if(f>0){if(!ze.compareByGeneratedPositionsInflated(l,A[f-1]))continue;c+=","}c+=Fc.encode(l.generatedColumn-t),t=l.generatedColumn,l.source!=null&&(d=this._sources.indexOf(l.source),c+=Fc.encode(d-s),s=d,c+=Fc.encode(l.originalLine-1-o),o=l.originalLine-1,c+=Fc.encode(l.originalColumn-n),n=l.originalColumn,l.name!=null&&(u=this._names.indexOf(l.name),c+=Fc.encode(u-i),i=u)),a+=c}return a};Tr.prototype._generateSourcesContent=function(t,r){return t.map(function(n){if(!this._sourcesContents)return null;r!=null&&(n=ze.relative(r,n));var o=ze.toSetString(n);return Object.prototype.hasOwnProperty.call(this._sourcesContents,o)?this._sourcesContents[o]:null},this)};Tr.prototype.toJSON=function(){var t={version:this._version,sources:this._sources.toArray(),names:this._names.toArray(),mappings:this._serializeMappings()};return this._file!=null&&(t.file=this._file),this._sourceRoot!=null&&(t.sourceRoot=this._sourceRoot),this._sourcesContents&&(t.sourcesContent=this._generateSourcesContent(t.sources,t.sourceRoot)),t};Tr.prototype.toString=function(){return JSON.stringify(this.toJSON())};c1.SourceMapGenerator=Tr});var l1=K(xi=>{xi.GREATEST_LOWER_BOUND=1;xi.LEAST_UPPER_BOUND=2;function kg(e,t,r,n,o,i){var s=Math.floor((t-e)/2)+e,a=o(r,n[s],!0);return a===0?s:a>0?t-s>1?kg(s,t,r,n,o,i):i==xi.LEAST_UPPER_BOUND?t<n.length?t:-1:s:s-e>1?kg(e,s,r,n,o,i):i==xi.LEAST_UPPER_BOUND?s:e<0?-1:e}xi.search=function(t,r,n,o){if(r.length===0)return-1;var i=kg(-1,r.length,t,r,n,o||xi.GREATEST_LOWER_BOUND);if(i<0)return-1;for(;i-1>=0&&n(r[i],r[i-1],!0)===0;)--i;return i}});var d1=K(f1=>{function GG(e){function t(o,i,s){var a=o[i];o[i]=o[s],o[s]=a}function r(o,i){return Math.round(o+Math.random()*(i-o))}function n(o,i,s,a){if(s<a){var c=r(s,a),l=s-1;t(o,c,a);for(var u=o[a],d=s;d<a;d++)i(o[d],u,!1)<=0&&(l+=1,t(o,l,d));t(o,l+1,d);var A=l+1;n(o,i,s,A-1),n(o,i,A+1,a)}}return n}function UG(e){let t=GG.toString();return new Function(`return ${t}`)()(e)}var u1=new WeakMap;f1.quickSort=function(e,t,r=0){let n=u1.get(t);n===void 0&&(n=UG(t),u1.set(t,n)),n(e,t,r,e.length-1)}});var p1=K(If=>{var H=Ys(),Ng=l1(),qs=Qg().ArraySet,HG=Bg(),Oc=d1().quickSort;function Re(e,t){var r=e;return typeof e=="string"&&(r=H.parseSourceMapInput(e)),r.sections!=null?new qr(r,t):new xt(r,t)}Re.fromSourceMap=function(e,t){return xt.fromSourceMap(e,t)};Re.prototype._version=3;Re.prototype.__generatedMappings=null;Object.defineProperty(Re.prototype,"_generatedMappings",{configurable:!0,enumerable:!0,get:function(){return this.__generatedMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__generatedMappings}});Re.prototype.__originalMappings=null;Object.defineProperty(Re.prototype,"_originalMappings",{configurable:!0,enumerable:!0,get:function(){return this.__originalMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__originalMappings}});Re.prototype._charIsMappingSeparator=function(t,r){var n=t.charAt(r);return n===";"||n===","};Re.prototype._parseMappings=function(t,r){throw new Error("Subclasses must implement _parseMappings")};Re.GENERATED_ORDER=1;Re.ORIGINAL_ORDER=2;Re.GREATEST_LOWER_BOUND=1;Re.LEAST_UPPER_BOUND=2;Re.prototype.eachMapping=function(t,r,n){var o=r||null,i=n||Re.GENERATED_ORDER,s;switch(i){case Re.GENERATED_ORDER:s=this._generatedMappings;break;case Re.ORIGINAL_ORDER:s=this._originalMappings;break;default:throw new Error("Unknown order of iteration.")}for(var a=this.sourceRoot,c=t.bind(o),l=this._names,u=this._sources,d=this._sourceMapURL,A=0,f=s.length;A<f;A++){var g=s[A],h=g.source===null?null:u.at(g.source);h!==null&&(h=H.computeSourceURL(a,h,d)),c({source:h,generatedLine:g.generatedLine,generatedColumn:g.generatedColumn,originalLine:g.originalLine,originalColumn:g.originalColumn,name:g.name===null?null:l.at(g.name)})}};Re.prototype.allGeneratedPositionsFor=function(t){var r=H.getArg(t,"line"),n={source:H.getArg(t,"source"),originalLine:r,originalColumn:H.getArg(t,"column",0)};if(n.source=this._findSourceIndex(n.source),n.source<0)return[];var o=[],i=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",H.compareByOriginalPositions,Ng.LEAST_UPPER_BOUND);if(i>=0){var s=this._originalMappings[i];if(t.column===void 0)for(var a=s.originalLine;s&&s.originalLine===a;)o.push({line:H.getArg(s,"generatedLine",null),column:H.getArg(s,"generatedColumn",null),lastColumn:H.getArg(s,"lastGeneratedColumn",null)}),s=this._originalMappings[++i];else for(var c=s.originalColumn;s&&s.originalLine===r&&s.originalColumn==c;)o.push({line:H.getArg(s,"generatedLine",null),column:H.getArg(s,"generatedColumn",null),lastColumn:H.getArg(s,"lastGeneratedColumn",null)}),s=this._originalMappings[++i]}return o};If.SourceMapConsumer=Re;function xt(e,t){var r=e;typeof e=="string"&&(r=H.parseSourceMapInput(e));var n=H.getArg(r,"version"),o=H.getArg(r,"sources"),i=H.getArg(r,"names",[]),s=H.getArg(r,"sourceRoot",null),a=H.getArg(r,"sourcesContent",null),c=H.getArg(r,"mappings"),l=H.getArg(r,"file",null);if(n!=this._version)throw new Error("Unsupported version: "+n);s&&(s=H.normalize(s)),o=o.map(String).map(H.normalize).map(function(u){return s&&H.isAbsolute(s)&&H.isAbsolute(u)?H.relative(s,u):u}),this._names=qs.fromArray(i.map(String),!0),this._sources=qs.fromArray(o,!0),this._absoluteSources=this._sources.toArray().map(function(u){return H.computeSourceURL(s,u,t)}),this.sourceRoot=s,this.sourcesContent=a,this._mappings=c,this._sourceMapURL=t,this.file=l}xt.prototype=Object.create(Re.prototype);xt.prototype.consumer=Re;xt.prototype._findSourceIndex=function(e){var t=e;if(this.sourceRoot!=null&&(t=H.relative(this.sourceRoot,t)),this._sources.has(t))return this._sources.indexOf(t);var r;for(r=0;r<this._absoluteSources.length;++r)if(this._absoluteSources[r]==e)return r;return-1};xt.fromSourceMap=function(t,r){var n=Object.create(xt.prototype),o=n._names=qs.fromArray(t._names.toArray(),!0),i=n._sources=qs.fromArray(t._sources.toArray(),!0);n.sourceRoot=t._sourceRoot,n.sourcesContent=t._generateSourcesContent(n._sources.toArray(),n.sourceRoot),n.file=t._file,n._sourceMapURL=r,n._absoluteSources=n._sources.toArray().map(function(f){return H.computeSourceURL(n.sourceRoot,f,r)});for(var s=t._mappings.toArray().slice(),a=n.__generatedMappings=[],c=n.__originalMappings=[],l=0,u=s.length;l<u;l++){var d=s[l],A=new m1;A.generatedLine=d.generatedLine,A.generatedColumn=d.generatedColumn,d.source&&(A.source=i.indexOf(d.source),A.originalLine=d.originalLine,A.originalColumn=d.originalColumn,d.name&&(A.name=o.indexOf(d.name)),c.push(A)),a.push(A)}return Oc(n.__originalMappings,H.compareByOriginalPositions),n};xt.prototype._version=3;Object.defineProperty(xt.prototype,"sources",{get:function(){return this._absoluteSources.slice()}});function m1(){this.generatedLine=0,this.generatedColumn=0,this.source=null,this.originalLine=null,this.originalColumn=null,this.name=null}var Dg=H.compareByGeneratedPositionsDeflatedNoLine;function A1(e,t){let r=e.length,n=e.length-t;if(!(n<=1))if(n==2){let o=e[t],i=e[t+1];Dg(o,i)>0&&(e[t]=i,e[t+1]=o)}else if(n<20)for(let o=t;o<r;o++)for(let i=o;i>t;i--){let s=e[i-1],a=e[i];if(Dg(s,a)<=0)break;e[i-1]=a,e[i]=s}else Oc(e,Dg,t)}xt.prototype._parseMappings=function(t,r){var n=1,o=0,i=0,s=0,a=0,c=0,l=t.length,u=0,d={},A={},f=[],g=[],h,y,E,x,S;let w=0;for(;u<l;)if(t.charAt(u)===";")n++,u++,o=0,A1(g,w),w=g.length;else if(t.charAt(u)===",")u++;else{for(h=new m1,h.generatedLine=n,x=u;x<l&&!this._charIsMappingSeparator(t,x);x++);for(y=t.slice(u,x),E=[];u<x;)HG.decode(t,u,A),S=A.value,u=A.rest,E.push(S);if(E.length===2)throw new Error("Found a source, but no line and column");if(E.length===3)throw new Error("Found a source and line, but no column");if(h.generatedColumn=o+E[0],o=h.generatedColumn,E.length>1&&(h.source=a+E[1],a+=E[1],h.originalLine=i+E[2],i=h.originalLine,h.originalLine+=1,h.originalColumn=s+E[3],s=h.originalColumn,E.length>4&&(h.name=c+E[4],c+=E[4])),g.push(h),typeof h.originalLine=="number"){let v=h.source;for(;f.length<=v;)f.push(null);f[v]===null&&(f[v]=[]),f[v].push(h)}}A1(g,w),this.__generatedMappings=g;for(var I=0;I<f.length;I++)f[I]!=null&&Oc(f[I],H.compareByOriginalPositionsNoSource);this.__originalMappings=[].concat(...f)};xt.prototype._findMapping=function(t,r,n,o,i,s){if(t[n]<=0)throw new TypeError("Line must be greater than or equal to 1, got "+t[n]);if(t[o]<0)throw new TypeError("Column must be greater than or equal to 0, got "+t[o]);return Ng.search(t,r,i,s)};xt.prototype.computeColumnSpans=function(){for(var t=0;t<this._generatedMappings.length;++t){var r=this._generatedMappings[t];if(t+1<this._generatedMappings.length){var n=this._generatedMappings[t+1];if(r.generatedLine===n.generatedLine){r.lastGeneratedColumn=n.generatedColumn-1;continue}}r.lastGeneratedColumn=1/0}};xt.prototype.originalPositionFor=function(t){var r={generatedLine:H.getArg(t,"line"),generatedColumn:H.getArg(t,"column")},n=this._findMapping(r,this._generatedMappings,"generatedLine","generatedColumn",H.compareByGeneratedPositionsDeflated,H.getArg(t,"bias",Re.GREATEST_LOWER_BOUND));if(n>=0){var o=this._generatedMappings[n];if(o.generatedLine===r.generatedLine){var i=H.getArg(o,"source",null);i!==null&&(i=this._sources.at(i),i=H.computeSourceURL(this.sourceRoot,i,this._sourceMapURL));var s=H.getArg(o,"name",null);return s!==null&&(s=this._names.at(s)),{source:i,line:H.getArg(o,"originalLine",null),column:H.getArg(o,"originalColumn",null),name:s}}}return{source:null,line:null,column:null,name:null}};xt.prototype.hasContentsOfAllSources=function(){return this.sourcesContent?this.sourcesContent.length>=this._sources.size()&&!this.sourcesContent.some(function(t){return t==null}):!1};xt.prototype.sourceContentFor=function(t,r){if(!this.sourcesContent)return null;var n=this._findSourceIndex(t);if(n>=0)return this.sourcesContent[n];var o=t;this.sourceRoot!=null&&(o=H.relative(this.sourceRoot,o));var i;if(this.sourceRoot!=null&&(i=H.urlParse(this.sourceRoot))){var s=o.replace(/^file:\/\//,"");if(i.scheme=="file"&&this._sources.has(s))return this.sourcesContent[this._sources.indexOf(s)];if((!i.path||i.path=="/")&&this._sources.has("/"+o))return this.sourcesContent[this._sources.indexOf("/"+o)]}if(r)return null;throw new Error('"'+o+'" is not in the SourceMap.')};xt.prototype.generatedPositionFor=function(t){var r=H.getArg(t,"source");if(r=this._findSourceIndex(r),r<0)return{line:null,column:null,lastColumn:null};var n={source:r,originalLine:H.getArg(t,"line"),originalColumn:H.getArg(t,"column")},o=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",H.compareByOriginalPositions,H.getArg(t,"bias",Re.GREATEST_LOWER_BOUND));if(o>=0){var i=this._originalMappings[o];if(i.source===n.source)return{line:H.getArg(i,"generatedLine",null),column:H.getArg(i,"generatedColumn",null),lastColumn:H.getArg(i,"lastGeneratedColumn",null)}}return{line:null,column:null,lastColumn:null}};If.BasicSourceMapConsumer=xt;function qr(e,t){var r=e;typeof e=="string"&&(r=H.parseSourceMapInput(e));var n=H.getArg(r,"version"),o=H.getArg(r,"sections");if(n!=this._version)throw new Error("Unsupported version: "+n);this._sources=new qs,this._names=new qs;var i={line:-1,column:0};this._sections=o.map(function(s){if(s.url)throw new Error("Support for url field in sections not implemented.");var a=H.getArg(s,"offset"),c=H.getArg(a,"line"),l=H.getArg(a,"column");if(c<i.line||c===i.line&&l<i.column)throw new Error("Section offsets must be ordered and non-overlapping.");return i=a,{generatedOffset:{generatedLine:c+1,generatedColumn:l+1},consumer:new Re(H.getArg(s,"map"),t)}})}qr.prototype=Object.create(Re.prototype);qr.prototype.constructor=Re;qr.prototype._version=3;Object.defineProperty(qr.prototype,"sources",{get:function(){for(var e=[],t=0;t<this._sections.length;t++)for(var r=0;r<this._sections[t].consumer.sources.length;r++)e.push(this._sections[t].consumer.sources[r]);return e}});qr.prototype.originalPositionFor=function(t){var r={generatedLine:H.getArg(t,"line"),generatedColumn:H.getArg(t,"column")},n=Ng.search(r,this._sections,function(i,s){var a=i.generatedLine-s.generatedOffset.generatedLine;return a||i.generatedColumn-s.generatedOffset.generatedColumn}),o=this._sections[n];return o?o.consumer.originalPositionFor({line:r.generatedLine-(o.generatedOffset.generatedLine-1),column:r.generatedColumn-(o.generatedOffset.generatedLine===r.generatedLine?o.generatedOffset.generatedColumn-1:0),bias:t.bias}):{source:null,line:null,column:null,name:null}};qr.prototype.hasContentsOfAllSources=function(){return this._sections.every(function(t){return t.consumer.hasContentsOfAllSources()})};qr.prototype.sourceContentFor=function(t,r){for(var n=0;n<this._sections.length;n++){var o=this._sections[n],i=o.consumer.sourceContentFor(t,!0);if(i||i==="")return i}if(r)return null;throw new Error('"'+t+'" is not in the SourceMap.')};qr.prototype.generatedPositionFor=function(t){for(var r=0;r<this._sections.length;r++){var n=this._sections[r];if(n.consumer._findSourceIndex(H.getArg(t,"source"))!==-1){var o=n.consumer.generatedPositionFor(t);if(o){var i={line:o.line+(n.generatedOffset.generatedLine-1),column:o.column+(n.generatedOffset.generatedLine===o.line?n.generatedOffset.generatedColumn-1:0)};return i}}}return{line:null,column:null}};qr.prototype._parseMappings=function(t,r){this.__generatedMappings=[],this.__originalMappings=[];for(var n=0;n<this._sections.length;n++)for(var o=this._sections[n],i=o.consumer._generatedMappings,s=0;s<i.length;s++){var a=i[s],c=o.consumer._sources.at(a.source);c!==null&&(c=H.computeSourceURL(o.consumer.sourceRoot,c,this._sourceMapURL)),this._sources.add(c),c=this._sources.indexOf(c);var l=null;a.name&&(l=o.consumer._names.at(a.name),this._names.add(l),l=this._names.indexOf(l));var u={source:c,generatedLine:a.generatedLine+(o.generatedOffset.generatedLine-1),generatedColumn:a.generatedColumn+(o.generatedOffset.generatedLine===a.generatedLine?o.generatedOffset.generatedColumn-1:0),originalLine:a.originalLine,originalColumn:a.originalColumn,name:l};this.__generatedMappings.push(u),typeof u.originalLine=="number"&&this.__originalMappings.push(u)}Oc(this.__generatedMappings,H.compareByGeneratedPositionsDeflated),Oc(this.__originalMappings,H.compareByOriginalPositions)};If.IndexedSourceMapConsumer=qr});var h1=K(g1=>{var VG=_g().SourceMapGenerator,Sf=Ys(),jG=/(\r?\n)/,$G=10,zs="$$$isSourceNode$$$";function ar(e,t,r,n,o){this.children=[],this.sourceContents={},this.line=e??null,this.column=t??null,this.source=r??null,this.name=o??null,this[zs]=!0,n!=null&&this.add(n)}ar.fromStringWithSourceMap=function(t,r,n){var o=new ar,i=t.split(jG),s=0,a=function(){var A=g(),f=g()||"";return A+f;function g(){return s<i.length?i[s++]:void 0}},c=1,l=0,u=null;return r.eachMapping(function(A){if(u!==null)if(c<A.generatedLine)d(u,a()),c++,l=0;else{var f=i[s]||"",g=f.substr(0,A.generatedColumn-l);i[s]=f.substr(A.generatedColumn-l),l=A.generatedColumn,d(u,g),u=A;return}for(;c<A.generatedLine;)o.add(a()),c++;if(l<A.generatedColumn){var f=i[s]||"";o.add(f.substr(0,A.generatedColumn)),i[s]=f.substr(A.generatedColumn),l=A.generatedColumn}u=A},this),s<i.length&&(u&&d(u,a()),o.add(i.splice(s).join(""))),r.sources.forEach(function(A){var f=r.sourceContentFor(A);f!=null&&(n!=null&&(A=Sf.join(n,A)),o.setSourceContent(A,f))}),o;function d(A,f){if(A===null||A.source===void 0)o.add(f);else{var g=n?Sf.join(n,A.source):A.source;o.add(new ar(A.originalLine,A.originalColumn,g,f,A.name))}}};ar.prototype.add=function(t){if(Array.isArray(t))t.forEach(function(r){this.add(r)},this);else if(t[zs]||typeof t=="string")t&&this.children.push(t);else throw new TypeError("Expected a SourceNode, string, or an array of SourceNodes and strings. Got "+t);return this};ar.prototype.prepend=function(t){if(Array.isArray(t))for(var r=t.length-1;r>=0;r--)this.prepend(t[r]);else if(t[zs]||typeof t=="string")this.children.unshift(t);else throw new TypeError("Expected a SourceNode, string, or an array of SourceNodes and strings. 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s=n;s<i;s++)e=e>>>8^o[(e^t[s])&255];return e^-1}var J1,K1=m(()=>{J1=function(){let e=qG();return J1=()=>e,e}});function Ug(e,t){var r,n,o,i,s,a,c,l,u,d,A,f,g,h,y,b,x,v,w,I,S,B,R,D,L;r=e.state,n=e.next_in,D=e.input,o=n+(e.avail_in-5),i=e.next_out,L=e.output,s=i-(t-e.avail_out),a=i+(e.avail_out-257),c=r.dmax,l=r.wsize,u=r.whave,d=r.wnext,A=r.window,f=r.hold,g=r.bits,h=r.lencode,y=r.distcode,b=(1<<r.lenbits)-1,x=(1<<r.distbits)-1;e:do{g<15&&(f+=D[n++]<<g,g+=8,f+=D[n++]<<g,g+=8),v=h[f&b];t:for(;;){if(w=v>>>24,f>>>=w,g-=w,w=v>>>16&255,w===0)L[i++]=v&65535;else if(w&16){I=v&65535,w&=15,w&&(g<w&&(f+=D[n++]<<g,g+=8),I+=f&(1<<w)-1,f>>>=w,g-=w),g<15&&(f+=D[n++]<<g,g+=8,f+=D[n++]<<g,g+=8),v=y[f&x];r:for(;;){if(w=v>>>24,f>>>=w,g-=w,w=v>>>16&255,w&16){if(S=v&65535,w&=15,g<w&&(f+=D[n++]<<g,g+=8,g<w&&(f+=D[n++]<<g,g+=8)),S+=f&(1<<w)-1,S>c){e.msg="invalid distance too far back",r.mode=Sf;break e}if(f>>>=w,g-=w,w=i-s,S>w){if(w=S-w,w>u&&r.sane){e.msg="invalid distance too far back",r.mode=Sf;break e}if(B=0,R=A,d===0){if(B+=l-w,w<I){I-=w;do L[i++]=A[B++];while(--w);B=i-S,R=L}}else if(d<w){if(B+=l+d-w,w-=d,w<I){I-=w;do L[i++]=A[B++];while(--w);if(B=0,d<I){w=d,I-=w;do L[i++]=A[B++];while(--w);B=i-S,R=L}}}else if(B+=d-w,w<I){I-=w;do L[i++]=A[B++];while(--w);B=i-S,R=L}for(;I>2;)L[i++]=R[B++],L[i++]=R[B++],L[i++]=R[B++],I-=3;I&&(L[i++]=R[B++],I>1&&(L[i++]=R[B++]))}else{B=i-S;do L[i++]=L[B++],L[i++]=L[B++],L[i++]=L[B++],I-=3;while(I>2);I&&(L[i++]=L[B++],I>1&&(L[i++]=L[B++]))}}else if((w&64)===0){v=y[(v&65535)+(f&(1<<w)-1)];continue r}else{e.msg="invalid distance code",r.mode=Sf;break e}break}}else if((w&64)===0){v=h[(v&65535)+(f&(1<<w)-1)];continue t}else if(w&32){r.mode=zG;break e}else{e.msg="invalid literal/length code",r.mode=Sf;break e}break}}while(n<o&&i<a);I=g>>3,n-=I,g-=I<<3,f&=(1<<g)-1,e.next_in=n,e.next_out=i,e.avail_in=n<o?5+(o-n):5-(n-o),e.avail_out=i<a?257+(a-i):257-(i-a),r.hold=f,r.bits=g}var Sf,zG,X1=m(()=>{Sf=30,zG=12});function yi(e,t,r,n,o,i,s,a){var c=a.bits,l=0,u=0,d=0,A=0,f=0,g=0,h=0,y=0,b=0,x=0,v,w,I,S,B,R=null,D=0,L,P=Co(Js+1),C=Co(Js+1),M=null,k=0,G,j,oe;for(l=0;l<=Js;l++)P[l]=0;for(u=0;u<n;u++)P[t[r+u]]++;for(f=c,A=Js;A>=1&&P[A]===0;A--);if(f>A&&(f=A),A===0)return o[i++]=1<<24|64<<16|0,o[i++]=1<<24|64<<16|0,a.bits=1,0;for(d=1;d<A&&P[d]===0;d++);for(f<d&&(f=d),y=1,l=1;l<=Js;l++)if(y<<=1,y-=P[l],y<0)return-1;if(y>0&&(e===tv||A!==1))return-1;for(C[1]=0,l=1;l<Js;l++)C[l+1]=C[l]+P[l];for(u=0;u<n;u++)t[r+u]!==0&&(s[C[t[r+u]]++]=u);if(e===tv?(R=M=s,L=19):e===Hg?(R=JG,D-=257,M=KG,k-=257,L=256):(R=XG,M=ZG,L=-1),x=0,u=0,l=d,B=i,g=f,h=0,I=-1,b=1<<f,S=b-1,e===Hg&&b>Z1||e===rv&&b>ev)return 1;for(;;){G=l-h,s[u]<L?(j=0,oe=s[u]):s[u]>L?(j=M[k+s[u]],oe=R[D+s[u]]):(j=96,oe=0),v=1<<l-h,w=1<<g,d=w;do w-=v,o[B+(x>>h)+w]=G<<24|j<<16|oe|0;while(w!==0);for(v=1<<l-1;x&v;)v>>=1;if(v!==0?(x&=v-1,x+=v):x=0,u++,--P[l]===0){if(l===A)break;l=t[r+s[u]]}if(l>f&&(x&S)!==I){for(h===0&&(h=f),B+=d,g=l-h,y=1<<g;g+h<A&&(y-=P[g+h],!(y<=0));)g++,y<<=1;if(b+=1<<g,e===Hg&&b>Z1||e===rv&&b>ev)return 1;I=x&S,o[I]=f<<24|g<<16|B-i|0}}return x!==0&&(o[B+x]=l-h<<24|64<<16|0),a.bits=f,0}var Js,Z1,ev,tv,Hg,rv,JG,KG,XG,ZG,nv=m(()=>{Fc();Js=15,Z1=852,ev=592,tv=0,Hg=1,rv=2,JG=[3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0],KG=[16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78],XG=[1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0],ZG=[16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64]});function Bv(e){return(e>>>24&255)+(e>>>8&65280)+((e&65280)<<8)+((e&255)<<24)}function c8(){this.mode=0,this.last=!1,this.wrap=0,this.havedict=!1,this.flags=0,this.dmax=0,this.check=0,this.total=0,this.head=null,this.wbits=0,this.wsize=0,this.whave=0,this.wnext=0,this.window=null,this.hold=0,this.bits=0,this.length=0,this.offset=0,this.extra=0,this.lencode=null,this.distcode=null,this.lenbits=0,this.distbits=0,this.ncode=0,this.nlen=0,this.ndist=0,this.have=0,this.next=null,this.lens=Co(320),this.work=Co(288),this.lendyn=null,this.distdyn=null,this.sane=0,this.back=0,this.was=0}function l8(e){var t;return!e||!e.state?vr:(t=e.state,e.total_in=e.total_out=t.total=0,e.msg="",t.wrap&&(e.adler=t.wrap&1),t.mode=_v,t.last=0,t.havedict=0,t.dmax=32768,t.head=null,t.hold=0,t.bits=0,t.lencode=t.lendyn=hi(s8),t.distcode=t.distdyn=hi(a8),t.sane=1,t.back=-1,xi)}function u8(e){var t;return!e||!e.state?vr:(t=e.state,t.wsize=0,t.whave=0,t.wnext=0,l8(e))}function f8(e,t){var r,n;return!e||!e.state||(n=e.state,t<0?(r=0,t=-t):(r=(t>>4)+1,t<48&&(t&=15)),t&&(t<8||t>15))?vr:(n.window!==null&&n.wbits!==t&&(n.window=null),n.wrap=r,n.wbits=t,u8(e))}function kv(e,t){var r,n;return e?(n=new c8,e.state=n,n.window=null,r=f8(e,t),r!==xi&&(e.state=null),r):vr}function d8(e){if(Tv){var t;for(Wg=hi(512),Yg=hi(32),t=0;t<144;)e.lens[t++]=8;for(;t<256;)e.lens[t++]=9;for(;t<280;)e.lens[t++]=7;for(;t<288;)e.lens[t++]=8;for(yi(Mv,e.lens,0,288,Wg,0,e.work,{bits:9}),t=0;t<32;)e.lens[t++]=5;yi(Rv,e.lens,0,32,Yg,0,e.work,{bits:5}),Tv=!1}e.lencode=Wg,e.lenbits=9,e.distcode=Yg,e.distbits=5}function Dv(e,t,r,n){var o,i=e.state;return i.window===null&&(i.wsize=1<<i.wbits,i.wnext=0,i.whave=0,i.window=qn(i.wsize)),n>=i.wsize?(xn(i.window,t,r-i.wsize,i.wsize,0),i.wnext=0,i.whave=i.wsize):(o=i.wsize-i.wnext,o>n&&(o=n),xn(i.window,t,r-n,o,i.wnext),n-=o,n?(xn(i.window,t,r-n,n,0),i.wnext=n,i.whave=i.wsize):(i.wnext+=o,i.wnext===i.wsize&&(i.wnext=0),i.whave<i.wsize&&(i.whave+=o))),0}function Nv(e,t){var r,n,o,i,s,a,c,l,u,d,A,f,g,h,y=0,b,x,v,w,I,S,B,R,D=qn(4),L,P,C=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15];if(!e||!e.state||!e.output||!e.input&&e.avail_in!==0)return vr;r=e.state,r.mode===zn&&(r.mode=Vg),s=e.next_out,o=e.output,c=e.avail_out,i=e.next_in,n=e.input,a=e.avail_in,l=r.hold,u=r.bits,d=a,A=c,R=xi;e:for(;;)switch(r.mode){case _v:if(r.wrap===0){r.mode=Vg;break}for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(r.wrap&2&&l===35615){r.check=0,D[0]=l&255,D[1]=l>>>8&255,r.check=Sr(r.check,D,2,0),l=0,u=0,r.mode=sv;break}if(r.flags=0,r.head&&(r.head.done=!1),!(r.wrap&1)||(((l&255)<<8)+(l>>8))%31){e.msg="incorrect header check",r.mode=Le;break}if((l&15)!==iv){e.msg="unknown compression method",r.mode=Le;break}if(l>>>=4,u-=4,B=(l&15)+8,r.wbits===0)r.wbits=B;else if(B>r.wbits){e.msg="invalid window size",r.mode=Le;break}r.dmax=1<<B,e.adler=r.check=1,r.mode=l&512?mv:zn,l=0,u=0;break;case sv:for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(r.flags=l,(r.flags&255)!==iv){e.msg="unknown compression method",r.mode=Le;break}if(r.flags&57344){e.msg="unknown header flags set",r.mode=Le;break}r.head&&(r.head.text=l>>8&1),r.flags&512&&(D[0]=l&255,D[1]=l>>>8&255,r.check=Sr(r.check,D,2,0)),l=0,u=0,r.mode=av;case av:for(;u<32;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.head&&(r.head.time=l),r.flags&512&&(D[0]=l&255,D[1]=l>>>8&255,D[2]=l>>>16&255,D[3]=l>>>24&255,r.check=Sr(r.check,D,4,0)),l=0,u=0,r.mode=cv;case cv:for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.head&&(r.head.xflags=l&255,r.head.os=l>>8),r.flags&512&&(D[0]=l&255,D[1]=l>>>8&255,r.check=Sr(r.check,D,2,0)),l=0,u=0,r.mode=lv;case lv:if(r.flags&1024){for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.length=l,r.head&&(r.head.extra_len=l),r.flags&512&&(D[0]=l&255,D[1]=l>>>8&255,r.check=Sr(r.check,D,2,0)),l=0,u=0}else r.head&&(r.head.extra=null);r.mode=uv;case uv:if(r.flags&1024&&(f=r.length,f>a&&(f=a),f&&(r.head&&(B=r.head.extra_len-r.length,r.head.extra||(r.head.extra=new Array(r.head.extra_len)),xn(r.head.extra,n,i,f,B)),r.flags&512&&(r.check=Sr(r.check,n,f,i)),a-=f,i+=f,r.length-=f),r.length))break e;r.length=0,r.mode=fv;case fv:if(r.flags&2048){if(a===0)break e;f=0;do B=n[i+f++],r.head&&B&&r.length<65536&&(r.head.name+=String.fromCharCode(B));while(B&&f<a);if(r.flags&512&&(r.check=Sr(r.check,n,f,i)),a-=f,i+=f,B)break e}else r.head&&(r.head.name=null);r.length=0,r.mode=dv;case dv:if(r.flags&4096){if(a===0)break e;f=0;do B=n[i+f++],r.head&&B&&r.length<65536&&(r.head.comment+=String.fromCharCode(B));while(B&&f<a);if(r.flags&512&&(r.check=Sr(r.check,n,f,i)),a-=f,i+=f,B)break e}else r.head&&(r.head.comment=null);r.mode=Av;case Av:if(r.flags&512){for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(l!==(r.check&65535)){e.msg="header crc mismatch",r.mode=Le;break}l=0,u=0}r.head&&(r.head.hcrc=r.flags>>9&1,r.head.done=!0),e.adler=r.check=0,r.mode=zn;break;case mv:for(;u<32;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}e.adler=r.check=Bv(l),l=0,u=0,r.mode=Mf;case Mf:if(r.havedict===0)return e.next_out=s,e.avail_out=c,e.next_in=i,e.avail_in=a,r.hold=l,r.bits=u,n8;e.adler=r.check=1,r.mode=zn;case zn:if(t===t8||t===vf)break e;case Vg:if(r.last){l>>>=u&7,u-=u&7,r.mode=$g;break}for(;u<3;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}switch(r.last=l&1,l>>>=1,u-=1,l&3){case 0:r.mode=pv;break;case 1:if(d8(r),r.mode=Bf,t===vf){l>>>=2,u-=2;break e}break;case 2:r.mode=hv;break;case 3:e.msg="invalid block type",r.mode=Le}l>>>=2,u-=2;break;case pv:for(l>>>=u&7,u-=u&7;u<32;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if((l&65535)!==(l>>>16^65535)){e.msg="invalid stored block lengths",r.mode=Le;break}if(r.length=l&65535,l=0,u=0,r.mode=jg,t===vf)break e;case jg:r.mode=gv;case gv:if(f=r.length,f){if(f>a&&(f=a),f>c&&(f=c),f===0)break e;xn(o,n,i,f,s),a-=f,i+=f,c-=f,s+=f,r.length-=f;break}r.mode=zn;break;case hv:for(;u<14;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(r.nlen=(l&31)+257,l>>>=5,u-=5,r.ndist=(l&31)+1,l>>>=5,u-=5,r.ncode=(l&15)+4,l>>>=4,u-=4,r.nlen>286||r.ndist>30){e.msg="too many length or distance symbols",r.mode=Le;break}r.have=0,r.mode=yv;case yv:for(;r.have<r.ncode;){for(;u<3;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}r.lens[C[r.have++]]=l&7,l>>>=3,u-=3}for(;r.have<19;)r.lens[C[r.have++]]=0;if(r.lencode=r.lendyn,r.lenbits=7,L={bits:r.lenbits},R=yi(e8,r.lens,0,19,r.lencode,0,r.work,L),r.lenbits=L.bits,R){e.msg="invalid code lengths set",r.mode=Le;break}r.have=0,r.mode=xv;case xv:for(;r.have<r.nlen+r.ndist;){for(;y=r.lencode[l&(1<<r.lenbits)-1],b=y>>>24,x=y>>>16&255,v=y&65535,!(b<=u);){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(v<16)l>>>=b,u-=b,r.lens[r.have++]=v;else{if(v===16){for(P=b+2;u<P;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(l>>>=b,u-=b,r.have===0){e.msg="invalid bit length 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r,n;return!e||!e.state||(n=e.state,t<0?(r=0,t=-t):(r=(t>>4)+1,t<48&&(t&=15)),t&&(t<8||t>15))?Qr:(n.window!==null&&n.wbits!==t&&(n.window=null),n.wrap=r,n.wbits=t,Q8(e))}function Uv(e,t){var r,n;return e?(n=new M8,e.state=n,n.window=null,r=_8(e,t),r!==Ei&&(e.state=null),r):Qr}function k8(e){if(Lv){var t;for(Kg=Ci(512),Xg=Ci(32),t=0;t<144;)e.lens[t++]=8;for(;t<256;)e.lens[t++]=9;for(;t<280;)e.lens[t++]=7;for(;t<288;)e.lens[t++]=8;for(bi(Pv,e.lens,0,288,Kg,0,e.work,{bits:9}),t=0;t<32;)e.lens[t++]=5;bi(Fv,e.lens,0,32,Xg,0,e.work,{bits:5}),Lv=!1}e.lencode=Kg,e.lenbits=9,e.distcode=Xg,e.distbits=5}function Hv(e,t,r,n){var o,i=e.state;return i.window===null&&(i.wsize=1<<i.wbits,i.wnext=0,i.whave=0,i.window=Kn(i.wsize)),n>=i.wsize?(En(i.window,t,r-i.wsize,i.wsize,0),i.wnext=0,i.whave=i.wsize):(o=i.wsize-i.wnext,o>n&&(o=n),En(i.window,t,r-n,o,i.wnext),n-=o,n?(En(i.window,t,r-n,n,0),i.wnext=n,i.whave=i.wsize):(i.wnext+=o,i.wnext===i.wsize&&(i.wnext=0),i.whave<i.wsize&&(i.whave+=o))),0}function Vv(e,t){var r,n,o,i,s,a,c,l,u,d,A,f,g,h,y=0,E,x,S,w,I,v,B,R,D=Kn(4),L,F,C=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15];if(!e||!e.state||!e.output||!e.input&&e.avail_in!==0)return Qr;r=e.state,r.mode===Xn&&(r.mode=qg),s=e.next_out,o=e.output,c=e.avail_out,i=e.next_in,n=e.input,a=e.avail_in,l=r.hold,u=r.bits,d=a,A=c,R=Ei;e:for(;;)switch(r.mode){case Gv:if(r.wrap===0){r.mode=qg;break}for(;u<16;){if(a===0)break e;a--,l+=n[i++]<<u,u+=8}if(r.wrap&2&&l===35615){r.check=0,D[0]=l&255,D[1]=l>>>8&255,r.check=Rr(r.check,D,2,0),l=0,u=0,r.mode=mv;break}if(r.flags=0,r.head&&(r.head.done=!1),!(r.wrap&1)||(((l&255)<<8)+(l>>8))%31){e.msg="incorrect header check",r.mode=Le;break}if((l&15)!==Av){e.msg="unknown compression method",r.mode=Le;break}if(l>>>=4,u-=4,B=(l&15)+8,r.wbits===0)r.wbits=B;else if(B>r.wbits){e.msg="invalid window size",r.mode=Le;break}r.dmax=1<<B,e.adler=r.check=1,r.mode=l&512?Ev:Xn,l=0,u=0;break;case mv:for(;u<16;){if(a===0)break 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  `);if(i===-1)continue;let s=o.slice(0,i).replace(/\r$/,""),a=s.indexOf(" "),c=a===-1?s:s.slice(0,a);c&&(r.push(o.slice(i+1).replaceAll(/\s/g,"")),n.push(c))}this.orderedNames=n,this.MSA={seqdata:this.expandA3M(r,n)}}static sniff(t){if(!t.startsWith(">"))return!1;let r=[];for(let s of t.split(">")){if(!/\S/.test(s))continue;let a=s.indexOf(`
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- `);if(a===-1)continue;let c=s.slice(a+1).replaceAll(/\s/g,"");c&&r.push(c)}if(r.length<2||new Set(r.map(s=>s.length)).size===1)return!1;let n=!1,o=-1,i=!0;for(let s of r){let a=0;for(let c=0;c<s.length;c++){let l=s.charCodeAt(c);fa(l)?n=!0:(l>=tR&&l<=rR||l===nR)&&a++}o===-1?o=a:a!==o&&(i=!1)}return n&&i}expandA3M(t,r){let n=r.length;if(n===0)return{};let o=[],i=[];for(let l=0;l<n;l++){let u=t[l],d=[],A=[],f=0;for(;f<u.length;){let g=u.charCodeAt(f);if(g>=tR&&g<=rR||g===nR){d.push(u[f]);let h="",y=f+1;for(;y<u.length;){let b=u.charCodeAt(y);if(fa(b)||b===oR)h+=u[y],y++;else break}A.push(h),f=y}else if(g===oR)f++;else if(fa(g)){let h="";for(;f<u.length&&fa(u.charCodeAt(f));)h+=u[f],f++;d.push(""),A.push(h)}else f++}o.push(d),i.push(A)}let s=Math.max(...o.map(l=>l.length),0),a=new Array(s).fill(0);for(let l=0;l<n;l++){let u=i[l];for(let d=0;d<u.length;d++){let A=0;for(let f of u[d])fa(f.charCodeAt(0))&&A++;A>a[d]&&(a[d]=A)}}let c={};for(let l=0;l<n;l++){let u=o[l],d=i[l],A=[];for(let f=0;f<s;f++){let g=a[f];if(f<u.length){let h=u[f],y=d[f]||"";A.push(h||"-");let b="";for(let v of y)fa(v.charCodeAt(0))&&(b+=v.toUpperCase());A.push(b);let x=g-b.length;x>0&&A.push(".".repeat(x))}else A.push("-"),g>0&&A.push(".".repeat(g))}c[r[l]]=A.join("")}return c}getMSA(){return this.MSA}getNames(){return this.orderedNames}getRow(t){return this.MSA.seqdata[t]||""}getWidth(){let t=Object.keys(this.MSA.seqdata)[0];return t?this.getRow(t).length:0}}});function aU(e){let t=/\(?(\d+(\.\d+)+)\)?/.exec(e);return t&&t.length>1?t[1]:""}function sR(e){let t=["CLUSTAL","PROBCONS","MUSCLE","MSAPROBS","Kalign"];t.some(n=>e.startsWith(n))||console.warn(`${e} is not a known CLUSTAL header: ${t.join(",")}, proceeding but could indicate an issue`);let r=aU(e);return{info:e,version:r}}function c0(e){let t=e.next();for(;!t.done&&t.value.trim()==="";)t=e.next();return t.value}function cU(e){let t=e.split(/\s+/),r=e.slice(t[0].length),n=t[0].length+r.indexOf(t[1]),o=n+t[1].length;return[n,o]}function iR(e){let t=c0(e),r=[],n="";if(!t)return;for(;t;)t.startsWith(" ")?n=t:r.push(t),t=e.next().value;let[o,i]=cU(r[0]),a=r.map(d=>d.split(/\s+/)).map(d=>d[0]),c=r.map(d=>d.slice(o,i)),l=n.slice(o,i),u=c[0].length-l.length;return u&&(l+=" ".repeat(u)),{ids:a,seqs:c,consensus:l}}function aR(e){let t,r=iR(e);if(r!==void 0)for(;t=iR(e);){for(let n=0;n<t.seqs.length;n++)r.seqs[n]+=t.seqs[n];r.consensus+=t.consensus}return r}var cR=m(()=>{});function lU(e){let t=c0(e);if(!t)throw new Error("Empty file received");let r=sR(t),n=aR(e);if(n===void 0)throw new Error("No blocks parsed");let o=n.seqs.map((s,a)=>({id:n.ids[a],seq:s})),{consensus:i}=n;if(i.length!==o[0].seq.length)throw new Error(`Consensus length != sequence length. Con ${i.length} seq ${o[0].seq.length}`);return{consensus:i,alns:o,header:r}}function lR(e){let t=e.split(`
40
- `)[Symbol.iterator]();return lU(t)}var uR=m(()=>{cR()});var Mo,l0=m(()=>{uR();ua();Mo=class extends lr{MSA;constructor(t){super(),this.MSA=lR(t)}getMSA(){return this.MSA}getRow(t){return this.MSA.alns.find(r=>r.id===t)?.seq??""}getWidth(){return this.MSA.alns[0]?.seq.length??0}getHeader(){return this.MSA.header}getNames(){return this.MSA.alns.map(t=>t.id)}get seqConsensus(){return this.MSA.consensus}}});function fR(e){let t=e.split(`
41
- `).map(i=>i.trim()).filter(i=>!!i),r=[],n=[];for(let i of t)if(i.startsWith("SEQ"))r.push(i);else{if(i.startsWith("DATA"))continue;if(i.startsWith("//"))break;n.push(i)}let o=r.map(i=>{let[,s,a,c,l,u,d,A,f]=i.split(" ");return{species:s,protein:a,chr:c,start:+l,end:+u,strand:+d,geneId:A,unknown:f,seq:""}});for(let i of n)for(let s=0;s<r.length;s++)o[s].seq+=i[s];return o}function id(e){let t=e.split(`
42
- `).map(i=>i.trim()).filter(i=>!!i),r=[],n="";for(let i of t)if(i.startsWith("SEQ"))r.push(i);else{if(i.startsWith("DATA"))continue;if(i.startsWith("//"))break;n=i}let o=r.map(i=>{let[,s,a,c,l,u,d,A,f]=i.split(" ");return{species:s,protein:a,chr:c,start:+l,end:+u,strand:+d,geneId:A,unknown:f}});return{tree:n,seqs:o}}var u0=m(()=>{});var Ro,f0=m(()=>{u0();ua();Ro=class extends lr{MSA;constructor(t){super(),this.MSA=fR(t)}getMSA(){return this.MSA}getRow(t){return this.MSA.find(r=>r.protein===t)?.seq??""}getWidth(){return this.MSA[0]?.seq.length??0}getNames(){return this.MSA.map(t=>t.protein)}}});var Qo,d0=m(()=>{ua();Qo=class extends lr{MSA;orderedNames=[];constructor(t){super();let r={},n={};for(let o of t.split(">")){if(!/\S/.test(o))continue;let i=o.indexOf(`
43
- `);if(i===-1)continue;let s=o.slice(0,i).replace(/\r$/,""),a=s.indexOf(" "),c=a===-1?s:s.slice(0,a);c&&(r[c]=o.slice(i+1).replaceAll(/\s/g,""),this.orderedNames.push(c),c.includes(":")&&(n[c.replaceAll(":","_")]=c))}this.MSA={seqdata:r,colonNormalized:n}}getMSA(){return this.MSA}getNames(){return this.orderedNames}getRow(t){return this.MSA.seqdata[t]??this.MSA.seqdata[this.MSA.colonNormalized[t]??""]??""}getWidth(){let t=this.orderedNames[0];return t===void 0?0:this.getRow(t).length}}});function vi(e){let t=[],r=[],n=e.replace(/'((?:[^']|'')*)'/g,(s,a)=>{let c=r.length;return r.push(a.replaceAll("''","'")),`__Q${c}__`}),o={},i=n.split(/\s*(;|\(|\)|,|:)\s*/);for(let s=0;s<i.length;s++){let c=i[s].replace(/^__Q(\d+)__$/,(u,d)=>r[Number(d)]),l={};switch(c){case"(":o.children=[l],t.push(o),o=l;break;case",":t.at(-1)?.children.push(l),o=l;break;case")":o=t.pop();break;case":":break;default:{let u=i[s-1];u===")"||u==="("||u===","?o.name=c:u===":"&&(o.length=Number.parseFloat(c))}}}return o}var A0=m(()=>{});function dR(){return{gf:{},gc:{},gs:{},gr:{},seqname:[],seqdata:{}}}function zc(e,t){if(e)return e;if(t)throw new Error("No format header: # STOCKHOLM 1.0");return dR()}function Jc(e){return AR.test(e)}function mR(e,t){let r=t??{},n=[],o=null,i=e.split(`
44
- `);for(let s of i){let a;if(AR.test(s))o=dR();else if(uU.test(s))o&&n.push(o),o=null;else if(a=fU.exec(s)){o=zc(o,!!r.strict);let c=a[1];o.gf[c]||(o.gf[c]=[]),o.gf[c].push(a[2])}else if(a=dU.exec(s)){o=zc(o,!!r.strict);let c=a[1];o.gc[c]||(o.gc[c]=""),o.gc[c]+=a[2]}else if(a=AU.exec(s)){o=zc(o,!!r.strict);let c=a[1],l=a[2],u=a[3];o.gs[l]||(o.gs[l]={}),o.gs[l][c]||(o.gs[l][c]=[]),o.gs[l][c].push(u)}else if(a=mU.exec(s)){o=zc(o,!!r.strict);let c=a[1],l=a[2],u=a[3];o.gr[l]||(o.gr[l]={}),o.gr[l][c]||(o.gr[l][c]=""),o.gr[l][c]+=u}else if(a=pU.exec(s)){o=zc(o,!!r.strict);let c=a[1],l=a[2];o.seqdata[c]||(o.seqdata[c]="",o.seqname.push(c)),o.seqdata[c]+=l}else if(gU.test(s)&&r.strict)throw new Error("Malformed line")}return o&&n.push(o),n}var AR,uU,fU,dU,AU,mU,pU,gU,m0=m(()=>{AR=/^# STOCKHOLM 1.0/,uU=/^\/\/\s*$/,fU=/^#=GF\s+(\S+)\s+(.*?)\s*$/,dU=/^#=GC\s+(\S+)\s+(.*?)\s*$/,AU=/^#=GS\s+(\S+)\s+(\S+)\s+(.*?)\s*$/,mU=/^#=GR\s+(\S+)\s+(\S+)\s+(.*?)\s*$/,pU=/^\s*(\S+)\s+(\S+)\s*$/,gU=/\S/});var _o,p0=m(()=>{s0();ua();A0();m0();m0();_o=class extends lr{data;MSA;constructor(t,r){super();let n=mR(t);this.data=n;let o=n[r]??n[0];if(!o)throw new Error("No alignments found in Stockholm file");this.MSA=o}getMSA(){return this.MSA}getRow(t){return this.MSA.seqdata[t]??""}getWidth(){let t=Object.keys(this.MSA.seqdata)[0];return t===void 0?0:this.getRow(t).length}get alignmentNames(){return this.data.map((t,r)=>t.gf.DE?.[0]??`Alignment ${r+1}`)}getHeader(){let t=this.MSA.gs.AC??{},r=this.MSA.gs.DR??{};return{General:this.MSA.gf,Accessions:Object.fromEntries(Object.entries(t).map(([n,o])=>[n,o[0]])),Dbxref:Object.fromEntries(Object.entries(r).map(([n,o])=>[n,o.join("; ")]))}}getRowData(t){return{name:t,accession:this.MSA.gs.AC?.[t]?.[0],dbxref:this.MSA.gs.DR?.[t]?.join("; ")}}getNames(){return Object.keys(this.MSA.seqdata)}getStructures(){let t=/PDB; +(\S+) +(\S); ([0-9]+)-([0-9]+)/,r=this.MSA.gs.DR??{},n={};for(let[o,i]of Object.entries(r))for(let s of i){let a=t.exec(s);a&&(n[o]??=[]).push({pdb:a[1].toLowerCase(),chain:a[2],startPos:+a[3],endPos:+a[4]})}return n}getTree(){let t=this.MSA.gf.NH?.[0];return t?la(vi(t)):super.getTree()}get seqConsensus(){return this.MSA.gc.seq_cons}get secondaryStructureConsensus(){return this.MSA.gc.SS_cons}get tracks(){return[{id:"seqConsensus",name:"Sequence consensus",data:this.seqConsensus,customColorScheme:{}},{id:"secondaryStruct",name:"Secondary-structure",data:this.secondaryStructureConsensus,customColorScheme:{"<":"lightblue","(":"lightblue","[":"lightblue","{":"lightblue",">":"pink",")":"pink","]":"pink","}":"pink"}}]}}});function g0(e,t=0,r){return r==="stockholm"?new _o(e,t):r==="a3m"?new Xn(e):r==="fasta"?new Qo(e):r==="emf"?new Ro(e):r==="clustal"?new Mo(e):Jc(e)?new _o(e,t):Xn.sniff(e)?new Xn(e):e.startsWith(">")?new Qo(e):e.startsWith("SEQ")?new Ro(e):new Mo(e)}function h0(e){return e.replaceAll(/[.-]/g,"")}var pR=m(()=>{a0();l0();f0();d0();p0();u0();A0();a0();l0();f0();d0();p0()});function hU(e){try{return decodeURIComponent(e)}catch{return e}}function yU(e){return e?Object.fromEntries(e.split(";").map(t=>t.trim()).filter(t=>!!t).map(t=>{let r=t.indexOf("="),n=(r===-1?t:t.slice(0,r)).trim(),o=r===-1?void 0:t.slice(r+1);return[n,o?o.split(",").map(i=>hU(i).trim()).join(" "):void 0]}).filter(([t])=>t!=="")):{}}function sd(e){return e?e.split(`
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- `).map(t=>t.trim()).filter(t=>!!t&&!t.startsWith("#")).map(t=>{let r=t.split(" "),[n,o,i,s,a,c,l,u]=r,d=r[8];return{seq_id:n??"",source:o??"",type:i??"",start:Number(s)||0,end:Number(a)||0,score:Number(c)||0,strand:l??".",phase:u??".",...yU(d)}}):[]}var gR=m(()=>{});function CU({type:e,strand:t}){let r=t==="+"?1:t==="-"?-1:void 0;return xU.has(e)?r:void 0}function ad(e){let t=new Map;for(let n of e){let o=t.get(n.seq_id);o?o.push(n):t.set(n.seq_id,[n])}let r={};for(let[n,o]of t){let i=new Map,s=new Map;for(let c of o){let l=c.Name||c.ID||`${c.source}_${c.start}_${c.end}`,u=c.signature_desc||c.Name||l,d=c.Ontology_term||c.description||c.Note||u;s.has(l)||s.set(l,{name:u,description:d,accession:l,featureType:c.type});let A={start:c.start,end:c.end,strand:CU(c)},f=i.get(l);f?f.push(A):i.set(l,[A])}let a=[];for(let[c,l]of i){let u=s.get(c);a.push({signature:{entry:u},locations:l})}r[n]={matches:a,xref:[{id:n}]}}return r}var xU,hR=m(()=>{xU=new Set(["gene","pseudogene","mRNA","transcript","primary_transcript","ncRNA","tRNA","rRNA","snRNA","snoRNA","miRNA","lnc_RNA"])});var yR=m(()=>{});var xR=m(()=>{gR();hR();yR()});var y0=m(()=>{s0();pR();xR()});async function IU({seq:e,onProgress:t,onJobId:r,programs:n,model:o,signal:i}){let s=await o0(`${x0}/iprscan5/run`,{method:"POST",body:new URLSearchParams({email:"colin.diesh@gmail.com",sequence:e,programs:n.join(",")}),signal:i});r?.(s),await vU({jobId:s,onProgress:t,signal:i}),await BU({jobId:s,model:o,onProgress:t,signal:i})}function SU(e,t){return nd(`${x0}/iprscan5/result/${e}/json`,{signal:t})}async function vU({onProgress:e,jobId:t,signal:r}){let n=`${x0}/iprscan5/status/${t}`,o=360;try{let i=!1;for(let s=0;s<o&&!i;s++){for(let c=0;c<10;c++)await JM(1e3,r),e({msg:`Checking status ${10-c}`,url:n});let a=(await o0(n,{signal:r})).trim();if(a==="FINISHED")i=!0;else if(a==="FAILURE"||a==="ERROR"||a==="NOT_FOUND")throw new Error(`InterProScan job ${t} ended with status: 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category",checked:!0},{name:"SignalP_GRAM_NEGATIVE",checked:!0,category:"Other category"},{name:"SuperFamily",category:"Structural domains",checked:!0},{name:"Panther",category:"Families, domains, sites & repeats",checked:!0},{name:"Gene3d",category:"Structural domains",checked:!0},{name:"HAMAP",category:"Families, domains, sites & repeats",checked:!0},{name:"PrositeProfiles",category:"Families, domains, sites & repeats",checked:!0},{name:"PrositePatterns",category:"Families, domains, sites & repeats",checked:!0},{name:"Coils",category:"Other sequence features",checked:!0},{name:"SMART",category:"Families, domains, sites & repeats",checked:!0},{name:"CDD",description:"Conserved Domains Database",category:"Families, domains, sites & repeats",checked:!0},{name:"PRINTS",category:"Families, domains, sites & repeats",checked:!0},{name:"PfamA",category:"Families, domains, sites & repeats",checked:!0},{name:"MobiDBLite",checked:!0,category:"Other sequence features"},{name:"PIRSF",checked:!0,category:"Other category"},{name:"TMHMM",checked:!0,category:"Other sequence features"},{name:"AntiFam",checked:!0,category:"Other category"},{name:"FunFam",checked:!0,category:"Other category"},{name:"PIRSR",checked:!0,category:"Families, domains, sites & repeats"}]),o=r.filter(a=>a.checked).map(a=>a.name),[i,s]=(0,Ge.useState)(!1);return Ge.default.createElement(bR.Dialog,{maxWidth:"xl",title:"Query InterProScan API for domains",onClose:()=>{e()},open:!0},Ge.default.createElement(ur.DialogContent,null,Ge.default.createElement(ur.Typography,null,"This will run InterProScan via the InterProScan API on all rows of the current MSA"),Ge.default.createElement(ur.Button,{onClick:()=>{s(!i)}},i?"Hide":"Show"," advanced options"),i?Ge.default.createElement("div",null,Ge.default.createElement(ur.Typography,null,"Select algorithms for InterProScan to 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all")),Ge.default.createElement("table",null,Ge.default.createElement("tbody",null,r.toSorted((a,c)=>a.category.localeCompare(c.category)).map(({name:a,checked:c,category:l})=>Ge.default.createElement("tr",{key:a},Ge.default.createElement("td",null,Ge.default.createElement("input",{type:"checkbox",key:a,checked:c,onChange:()=>{n(r.map(u=>u.name===a?{...u,checked:!u.checked}:u))}})),Ge.default.createElement("td",null,a),Ge.default.createElement("td",null,l)))))):null),Ge.default.createElement(ur.DialogActions,null,Ge.default.createElement(ur.Button,{variant:"contained",color:"secondary",onClick:()=>{e()}},"Cancel"),Ge.default.createElement(ur.Button,{variant:"contained",color:"primary",onClick:()=>{let a=new AbortController;(async()=>{try{let{rows:c}=t;if(c.length>140)throw new Error("Too many sequences, please run InterProScan offline");await CR({algorithm:"interproscan",programs:o,seq:c.map(l=>[l[0],h0(l[1])]).filter(l=>!!l[1]).map(l=>`>${l[0]}
39
+ `);if(a===-1)continue;let c=s.slice(a+1).replaceAll(/\s/g,"");c&&r.push(c)}if(r.length<2||new Set(r.map(s=>s.length)).size===1)return!1;let n=!1,o=-1,i=!0;for(let s of r){let a=0;for(let c=0;c<s.length;c++){let l=s.charCodeAt(c);pa(l)?n=!0:(l>=uR&&l<=fR||l===dR)&&a++}o===-1?o=a:a!==o&&(i=!1)}return n&&i}expandA3M(t,r){let n=r.length;if(n===0)return{};let o=[],i=[];for(let l=0;l<n;l++){let u=t[l],d=[],A=[],f=0;for(;f<u.length;){let g=u.charCodeAt(f);if(g>=uR&&g<=fR||g===dR){d.push(u[f]);let h="",y=f+1;for(;y<u.length;){let E=u.charCodeAt(y);if(pa(E)||E===AR)h+=u[y],y++;else break}A.push(h),f=y}else if(g===AR)f++;else if(pa(g)){let h="";for(;f<u.length&&pa(u.charCodeAt(f));)h+=u[f],f++;d.push(""),A.push(h)}else f++}o.push(d),i.push(A)}let s=Math.max(...o.map(l=>l.length),0),a=new Array(s).fill(0);for(let l=0;l<n;l++){let u=i[l];for(let d=0;d<u.length;d++){let A=0;for(let f of u[d])pa(f.charCodeAt(0))&&A++;A>a[d]&&(a[d]=A)}}let c={};for(let l=0;l<n;l++){let u=o[l],d=i[l],A=[];for(let f=0;f<s;f++){let g=a[f];if(f<u.length){let h=u[f],y=d[f]||"";A.push(h||"-");let E="";for(let S of y)pa(S.charCodeAt(0))&&(E+=S.toUpperCase());A.push(E);let x=g-E.length;x>0&&A.push(".".repeat(x))}else A.push("-"),g>0&&A.push(".".repeat(g))}c[r[l]]=A.join("")}return c}getMSA(){return this.MSA}getNames(){return this.orderedNames}getRow(t){return this.MSA.seqdata[t]||""}getWidth(){let t=Object.keys(this.MSA.seqdata)[0];return t?this.getRow(t).length:0}}});function MU(e){let t=/\(?(\d+(\.\d+)+)\)?/.exec(e);return t&&t.length>1?t[1]:""}function pR(e){let t=["CLUSTAL","PROBCONS","MUSCLE","MSAPROBS","Kalign"];t.some(n=>e.startsWith(n))||console.warn(`${e} is not a known CLUSTAL header: ${t.join(",")}, proceeding but could indicate an issue`);let r=MU(e);return{info:e,version:r}}function A0(e){let t=e.next();for(;!t.done&&t.value.trim()==="";)t=e.next();return t.value}function RU(e){let t=e.split(/\s+/),r=e.slice(t[0].length),n=t[0].length+r.indexOf(t[1]),o=n+t[1].length;return[n,o]}function mR(e){let t=A0(e),r=[],n="";if(!t)return;for(;t;)t.startsWith(" ")?n=t:r.push(t),t=e.next().value;let[o,i]=RU(r[0]),a=r.map(d=>d.split(/\s+/)).map(d=>d[0]),c=r.map(d=>d.slice(o,i)),l=n.slice(o,i),u=c[0].length-l.length;return u&&(l+=" ".repeat(u)),{ids:a,seqs:c,consensus:l}}function gR(e){let t,r=mR(e);if(r!==void 0)for(;t=mR(e);){for(let n=0;n<t.seqs.length;n++)r.seqs[n]+=t.seqs[n];r.consensus+=t.consensus}return r}var hR=m(()=>{});function QU(e){let t=A0(e);if(!t)throw new Error("Empty file received");let r=pR(t),n=gR(e);if(n===void 0)throw new Error("No blocks parsed");let o=n.seqs.map((s,a)=>({id:n.ids[a],seq:s})),{consensus:i}=n;if(i.length!==o[0].seq.length)throw new Error(`Consensus length != sequence length. Con ${i.length} seq ${o[0].seq.length}`);return{consensus:i,alns:o,header:r}}function yR(e){let t=e.split(`
40
+ `)[Symbol.iterator]();return QU(t)}var xR=m(()=>{hR()});var _o,m0=m(()=>{xR();ma();_o=class extends dr{MSA;constructor(t){super(),this.MSA=yR(t)}getMSA(){return this.MSA}getRow(t){return this.MSA.alns.find(r=>r.id===t)?.seq??""}getWidth(){return this.MSA.alns[0]?.seq.length??0}getHeader(){return this.MSA.header}getNames(){return this.MSA.alns.map(t=>t.id)}get seqConsensus(){return this.MSA.consensus}}});function CR(e){let t=e.split(`
41
+ `).map(i=>i.trim()).filter(i=>!!i),r=[],n=[];for(let i of t)if(i.startsWith("SEQ"))r.push(i);else{if(i.startsWith("DATA"))continue;if(i.startsWith("//"))break;n.push(i)}let o=r.map(i=>{let[,s,a,c,l,u,d,A,f]=i.split(" ");return{species:s,protein:a,chr:c,start:+l,end:+u,strand:+d,geneId:A,unknown:f,seq:""}});for(let i of n)for(let s=0;s<r.length;s++)o[s].seq+=i[s];return o}function dd(e){let t=e.split(`
42
+ `).map(i=>i.trim()).filter(i=>!!i),r=[],n="";for(let i of t)if(i.startsWith("SEQ"))r.push(i);else{if(i.startsWith("DATA"))continue;if(i.startsWith("//"))break;n=i}let o=r.map(i=>{let[,s,a,c,l,u,d,A,f]=i.split(" ");return{species:s,protein:a,chr:c,start:+l,end:+u,strand:+d,geneId:A,unknown:f}});return{tree:n,seqs:o}}var p0=m(()=>{});var ko,g0=m(()=>{p0();ma();ko=class extends dr{MSA;constructor(t){super(),this.MSA=CR(t)}getMSA(){return this.MSA}getRow(t){return this.MSA.find(r=>r.protein===t)?.seq??""}getWidth(){return this.MSA[0]?.seq.length??0}getNames(){return this.MSA.map(t=>t.protein)}}});var Do,h0=m(()=>{ma();Do=class extends dr{MSA;orderedNames=[];constructor(t){super();let r={},n={};for(let o of t.split(">")){if(!/\S/.test(o))continue;let i=o.indexOf(`
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+ `);if(i===-1)continue;let s=o.slice(0,i).replace(/\r$/,""),a=s.indexOf(" "),c=a===-1?s:s.slice(0,a);c&&(r[c]=o.slice(i+1).replaceAll(/\s/g,""),this.orderedNames.push(c),c.includes(":")&&(n[c.replaceAll(":","_")]=c))}this.MSA={seqdata:r,colonNormalized:n}}getMSA(){return this.MSA}getNames(){return this.orderedNames}getRow(t){return this.MSA.seqdata[t]??this.MSA.seqdata[this.MSA.colonNormalized[t]??""]??""}getWidth(){let t=this.orderedNames[0];return t===void 0?0:this.getRow(t).length}}});function Mi(e){let t=[],r=[],n=e.replace(/'((?:[^']|'')*)'/g,(s,a)=>{let c=r.length;return r.push(a.replaceAll("''","'")),`__Q${c}__`}),o={},i=n.split(/\s*(;|\(|\)|,|:)\s*/);for(let s=0;s<i.length;s++){let c=i[s].replace(/^__Q(\d+)__$/,(u,d)=>r[Number(d)]),l={};switch(c){case"(":o.children=[l],t.push(o),o=l;break;case",":t.at(-1)?.children.push(l),o=l;break;case")":o=t.pop();break;case":":break;default:{let u=i[s-1];u===")"||u==="("||u===","?o.name=c:u===":"&&(o.length=Number.parseFloat(c))}}}return o}var y0=m(()=>{});function bR(){return{gf:{},gc:{},gs:{},gr:{},seqname:[],seqdata:{}}}function nl(e,t){if(e)return e;if(t)throw new Error("No format header: # STOCKHOLM 1.0");return bR()}function ol(e){return ER.test(e)}function wR(e,t){let r=t??{},n=[],o=null,i=e.split(`
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+ `);for(let s of i){let a;if(ER.test(s))o=bR();else if(_U.test(s))o&&n.push(o),o=null;else if(a=kU.exec(s)){o=nl(o,!!r.strict);let c=a[1];o.gf[c]||(o.gf[c]=[]),o.gf[c].push(a[2])}else if(a=DU.exec(s)){o=nl(o,!!r.strict);let c=a[1];o.gc[c]||(o.gc[c]=""),o.gc[c]+=a[2]}else if(a=NU.exec(s)){o=nl(o,!!r.strict);let c=a[1],l=a[2],u=a[3];o.gs[l]||(o.gs[l]={}),o.gs[l][c]||(o.gs[l][c]=[]),o.gs[l][c].push(u)}else if(a=LU.exec(s)){o=nl(o,!!r.strict);let c=a[1],l=a[2],u=a[3];o.gr[l]||(o.gr[l]={}),o.gr[l][c]||(o.gr[l][c]=""),o.gr[l][c]+=u}else if(a=PU.exec(s)){o=nl(o,!!r.strict);let c=a[1],l=a[2];o.seqdata[c]||(o.seqdata[c]="",o.seqname.push(c)),o.seqdata[c]+=l}else if(FU.test(s)&&r.strict)throw new Error("Malformed line")}return o&&n.push(o),n}var ER,_U,kU,DU,NU,LU,PU,FU,x0=m(()=>{ER=/^# STOCKHOLM 1.0/,_U=/^\/\/\s*$/,kU=/^#=GF\s+(\S+)\s+(.*?)\s*$/,DU=/^#=GC\s+(\S+)\s+(.*?)\s*$/,NU=/^#=GS\s+(\S+)\s+(\S+)\s+(.*?)\s*$/,LU=/^#=GR\s+(\S+)\s+(\S+)\s+(.*?)\s*$/,PU=/^\s*(\S+)\s+(\S+)\s*$/,FU=/\S/});var No,C0=m(()=>{f0();ma();y0();x0();x0();No=class extends dr{data;MSA;constructor(t,r){super();let n=wR(t);this.data=n;let o=n[r]??n[0];if(!o)throw new Error("No alignments found in Stockholm file");this.MSA=o}getMSA(){return this.MSA}getRow(t){return this.MSA.seqdata[t]??""}getWidth(){let t=Object.keys(this.MSA.seqdata)[0];return t===void 0?0:this.getRow(t).length}get alignmentNames(){return this.data.map((t,r)=>t.gf.DE?.[0]??`Alignment ${r+1}`)}getHeader(){let t=this.MSA.gs.AC??{},r=this.MSA.gs.DR??{};return{General:this.MSA.gf,Accessions:Object.fromEntries(Object.entries(t).map(([n,o])=>[n,o[0]])),Dbxref:Object.fromEntries(Object.entries(r).map(([n,o])=>[n,o.join("; ")]))}}getRowData(t){return{name:t,accession:this.MSA.gs.AC?.[t]?.[0],dbxref:this.MSA.gs.DR?.[t]?.join("; ")}}getNames(){return Object.keys(this.MSA.seqdata)}getStructures(){let t=/PDB; +(\S+) +(\S); ([0-9]+)-([0-9]+)/,r=this.MSA.gs.DR??{},n={};for(let[o,i]of Object.entries(r))for(let s of i){let a=t.exec(s);a&&(n[o]??=[]).push({pdb:a[1].toLowerCase(),chain:a[2],startPos:+a[3],endPos:+a[4]})}return n}getTree(){let t=this.MSA.gf.NH?.[0];return t?Aa(Mi(t)):super.getTree()}get seqConsensus(){return this.MSA.gc.seq_cons}get secondaryStructureConsensus(){return this.MSA.gc.SS_cons}get tracks(){return[{id:"seqConsensus",name:"Sequence consensus",data:this.seqConsensus,customColorScheme:{}},{id:"secondaryStruct",name:"Secondary-structure",data:this.secondaryStructureConsensus,customColorScheme:{"<":"lightblue","(":"lightblue","[":"lightblue","{":"lightblue",">":"pink",")":"pink","]":"pink","}":"pink"}}]}}});function b0(e,t=0,r){return r==="stockholm"?new No(e,t):r==="a3m"?new to(e):r==="fasta"?new Do(e):r==="emf"?new ko(e):r==="clustal"?new _o(e):ol(e)?new No(e,t):to.sniff(e)?new to(e):e.startsWith(">")?new Do(e):e.startsWith("SEQ")?new ko(e):new _o(e)}function E0(e){return e.replaceAll(/[.-]/g,"")}var IR=m(()=>{d0();m0();g0();h0();C0();p0();y0();d0();m0();g0();h0();C0()});function OU(e){try{return decodeURIComponent(e)}catch{return e}}function GU(e){return e?Object.fromEntries(e.split(";").map(t=>t.trim()).filter(t=>!!t).map(t=>{let r=t.indexOf("="),n=(r===-1?t:t.slice(0,r)).trim(),o=r===-1?void 0:t.slice(r+1);return[n,o?o.split(",").map(i=>OU(i).trim()).join(" "):void 0]}).filter(([t])=>t!=="")):{}}function Ad(e){return e?e.split(`
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+ `).map(t=>t.trim()).filter(t=>!!t&&!t.startsWith("#")).map(t=>{let r=t.split(" "),[n,o,i,s,a,c,l,u]=r,d=r[8];return{seq_id:n??"",source:o??"",type:i??"",start:Number(s)||0,end:Number(a)||0,score:Number(c)||0,strand:l??".",phase:u??".",...GU(d)}}):[]}var SR=m(()=>{});function HU({type:e,strand:t}){let r=t==="+"?1:t==="-"?-1:void 0;return UU.has(e)?r:void 0}function md(e){let t=new Map;for(let n of e){let o=t.get(n.seq_id);o?o.push(n):t.set(n.seq_id,[n])}let r={};for(let[n,o]of t){let i=new Map,s=new Map;for(let c of o){let l=c.Name||c.ID||`${c.source}_${c.start}_${c.end}`,u=c.signature_desc||c.Name||l,d=c.Ontology_term||c.description||c.Note||u;s.has(l)||s.set(l,{name:u,description:d,accession:l,featureType:c.type});let A={start:c.start,end:c.end,strand:HU(c)},f=i.get(l);f?f.push(A):i.set(l,[A])}let a=[];for(let[c,l]of i){let u=s.get(c);a.push({signature:{entry:u},locations:l})}r[n]={matches:a,xref:[{id:n}]}}return r}var UU,vR=m(()=>{UU=new Set(["gene","pseudogene","mRNA","transcript","primary_transcript","ncRNA","tRNA","rRNA","snRNA","snoRNA","miRNA","lnc_RNA"])});var BR=m(()=>{});var TR=m(()=>{SR();vR();BR()});var w0=m(()=>{f0();IR();TR()});async function WU({seq:e,onProgress:t,onJobId:r,programs:n,model:o,signal:i}){let s=await l0(`${I0}/iprscan5/run`,{method:"POST",body:new URLSearchParams({email:"colin.diesh@gmail.com",sequence:e,programs:n.join(",")}),signal:i});r?.(s),await qU({jobId:s,onProgress:t,signal:i}),await zU({jobId:s,model:o,onProgress:t,signal:i})}function YU(e,t){return ud(`${I0}/iprscan5/result/${e}/json`,{signal:t})}async function qU({onProgress:e,jobId:t,signal:r}){let n=`${I0}/iprscan5/status/${t}`,o=360;try{let i=!1;for(let s=0;s<o&&!i;s++){for(let c=0;c<10;c++)await iR(1e3,r),e({msg:`Checking status ${10-c}`,url:n});let a=(await l0(n,{signal:r})).trim();if(a==="FINISHED")i=!0;else if(a==="FAILURE"||a==="ERROR"||a==="NOT_FOUND")throw new Error(`InterProScan job ${t} ended with status: ${a}`)}if(!i)throw new Error(`InterProScan job ${t} did not finish after ${o} status checks`)}finally{e()}}async function MR({algorithm:e,seq:t,programs:r,onJobId:n,onProgress:o,model:i,signal:s}){try{if(o({msg:`Launching ${e} MSA`}),e==="interproscan")await WU({seq:t,onJobId:n,onProgress:o,programs:r,model:i,signal:s});else throw new Error("unknown algorithm")}catch(a){if(Qo(a))(0,il.getSession)(i).notify("Cancelled InterProScan query","info");else throw a}finally{o()}}async function zU({jobId:e,model:t,onProgress:r,signal:n}){try{r({msg:`Downloading results of ${e} (for larger sequences this can be slow, click status to download and upload in the manual tab)`,url:`https://www.ebi.ac.uk/Tools/services/rest/iprscan5/result/${e}/json`});let o=await YU(e,n);t.setDomains(Object.fromEntries(o.results.map(i=>[i.xref[0]?.id,i]).filter(i=>i[0]!==void 0))),(0,il.getSession)(t).notify(`Loaded interproscan ${e} results`,"success")}catch(o){Qo(o)?(0,il.getSession)(t).notify("Cancelled InterProScan query","info"):(console.error(o),(0,il.getSession)(t).notifyError(`${o}`,o))}finally{r()}}var il,I0,RR=m(()=>{il=p(we(),1);fd();I0="https://www.ebi.ac.uk/Tools/services/rest"});var DR={};Bt(DR,{default:()=>KU});var Ge,QR,_R,Ar,kR,JU,KU,NR=m(()=>{Ge=p(Q(),1),QR=p(Ze(),1),_R=p(we(),1),Ar=p(U(),1),kR=p(W(),1);w0();RR();JU=(0,kR.observer)(function({handleClose:e,model:t}){let[r,n]=(0,Ge.useState)([{name:"NCBIfam",description:"NCBI RefSeq FAMs including TIGRFAMs",category:"Families, domains, sites & repeats",checked:!0},{name:"SFLD",description:"Structure function linkage database",category:"Families, domains, sites & repeats",checked:!0},{name:"Phobius",checked:!0,description:"A combined transmembrane topology and signal peptide predictor",category:"Other sequence features"},{name:"SignalP",checked:!0,category:"Other sequence features"},{name:"SignalP_EUK",category:"Other category",checked:!0},{name:"SignalP_GRAM_POSITIVE",category:"Other category",checked:!0},{name:"SignalP_GRAM_NEGATIVE",checked:!0,category:"Other category"},{name:"SuperFamily",category:"Structural domains",checked:!0},{name:"Panther",category:"Families, domains, sites & repeats",checked:!0},{name:"Gene3d",category:"Structural domains",checked:!0},{name:"HAMAP",category:"Families, domains, sites & repeats",checked:!0},{name:"PrositeProfiles",category:"Families, domains, sites & repeats",checked:!0},{name:"PrositePatterns",category:"Families, domains, sites & repeats",checked:!0},{name:"Coils",category:"Other sequence features",checked:!0},{name:"SMART",category:"Families, domains, sites & repeats",checked:!0},{name:"CDD",description:"Conserved Domains Database",category:"Families, domains, sites & repeats",checked:!0},{name:"PRINTS",category:"Families, domains, sites & repeats",checked:!0},{name:"PfamA",category:"Families, domains, sites & repeats",checked:!0},{name:"MobiDBLite",checked:!0,category:"Other sequence features"},{name:"PIRSF",checked:!0,category:"Other category"},{name:"TMHMM",checked:!0,category:"Other sequence features"},{name:"AntiFam",checked:!0,category:"Other category"},{name:"FunFam",checked:!0,category:"Other category"},{name:"PIRSR",checked:!0,category:"Families, domains, sites & repeats"}]),o=r.filter(a=>a.checked).map(a=>a.name),[i,s]=(0,Ge.useState)(!1);return Ge.default.createElement(QR.Dialog,{maxWidth:"xl",title:"Query InterProScan API for domains",onClose:()=>{e()},open:!0},Ge.default.createElement(Ar.DialogContent,null,Ge.default.createElement(Ar.Typography,null,"This will run InterProScan via the InterProScan API on all rows of the current MSA"),Ge.default.createElement(Ar.Button,{onClick:()=>{s(!i)}},i?"Hide":"Show"," advanced options"),i?Ge.default.createElement("div",null,Ge.default.createElement(Ar.Typography,null,"Select algorithms for InterProScan to run"),Ge.default.createElement("div",null,Ge.default.createElement(Ar.Button,{variant:"contained",color:"secondary",onClick:()=>{n(r.map(a=>({...a,checked:!1})))}},"Select none"),Ge.default.createElement(Ar.Button,{variant:"contained",color:"primary",onClick:()=>{n(r.map(a=>({...a,checked:!0})))}},"Select all")),Ge.default.createElement("table",null,Ge.default.createElement("tbody",null,r.toSorted((a,c)=>a.category.localeCompare(c.category)).map(({name:a,checked:c,category:l})=>Ge.default.createElement("tr",{key:a},Ge.default.createElement("td",null,Ge.default.createElement("input",{type:"checkbox",key:a,checked:c,onChange:()=>{n(r.map(u=>u.name===a?{...u,checked:!u.checked}:u))}})),Ge.default.createElement("td",null,a),Ge.default.createElement("td",null,l)))))):null),Ge.default.createElement(Ar.DialogActions,null,Ge.default.createElement(Ar.Button,{variant:"contained",color:"secondary",onClick:()=>{e()}},"Cancel"),Ge.default.createElement(Ar.Button,{variant:"contained",color:"primary",onClick:()=>{let a=new AbortController;(async()=>{try{let{rows:c}=t;if(c.length>140)throw new Error("Too many sequences, please run InterProScan offline");await MR({algorithm:"interproscan",programs:o,seq:c.map(l=>[l[0],E0(l[1])]).filter(l=>!!l[1]).map(l=>`>${l[0]}
46
46
  ${l[1]}`).join(`
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sequence alignment
50
50
  UniProt/Swiss-Prot|P26898|IL2RA_SHEEP MEPSLLMWRFFVFIVVPGCVTEACHDDPPSLRNA----------MFKVLRYE----VGTM
51
51
  UniProt/Swiss-Prot|P01590|IL2RA_MOUSE MEPRLLMLGFLSLTIVPSCRAELCLYDPPEVPNA----------TFKALSYK----NGTI
52
52
  UniProt/Swiss-Prot|P41690|IL2RA_FELCA MEPSLLLWGILTFVVVHGHVTELCDENPPDIQHA----------TFKALTYK----TGTM
@@ -59,7 +59,7 @@ UniProt/Swiss-Prot|Q8BZM1|GLMN_MOUSE PLPLRSLLFLQLPLLGVGLNP----------------
59
59
  UniProt/Swiss-Prot|P36835|IL2_CAPHI -----------LLGVGLNPKFLTP------------------------------------
60
60
  UniProt/Swiss-Prot|Q7JFM4|IL2_AOTVO MLKPPLPLRSLLFLQLPLLGVGLNPKFLTPSGNEDIGGKPGTGGDFFLTSTPAGTLDVST
61
61
  UniProt/Swiss-Prot|Q29416|IL2_CANFA --------------LFLQLSLLG-------------------------------------
62
- `,Fk=`CLUSTAL O(1.2.4) multiple sequence alignment
62
+ `,Wk=`CLUSTAL O(1.2.4) multiple sequence alignment
63
63
 
64
64
 
65
65
  sp|P69905|HBA_HUMAN MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG 60
@@ -75,14 +75,18 @@ sp|P13786|HBAZ_CAPHI SKVVAAVGDAVKSIDNVTSALSKLSELHAYVLRVDPVNFKFLSHCLLVTLASHF
75
75
  sp|P69905|HBA_HUMAN AVHASLDKFLASVSTVLTSKYR 142
76
76
  sp|P01942|HBA_MOUSE AVHASLDKFLASVSTVLTSKYR 142
77
77
  sp|P13786|HBAZ_CAPHI DAHAAWDKFLSIVSGVLTEKYR 142
78
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Map(this.rows.map(([t,r])=>[t,VD(r)]))},get rowMap(){return new Map(this.rows)},get columns(){let t=this.columns2d;return new Map(this.rows.map((r,n)=>[r[0],t[n]]))},get columns2d(){let{hideGapsEffective:t}=e;return this.rows.map(([,r])=>(t?$p(this.blanks,r):r).toUpperCase())},get fontSize(){return Math.min(Math.max(6,e.rowHeight-3),18)},get colStats(){return uD(this.columns2d)},get colStatsSums(){return this.colStats.totals},get sequenceType(){let t=this.colStats.lettersPresent,r=new Set(["A","C","G","T","N"]),n=new Set(["A","C","G","U","N"]),o=t.size>0&&[...t].every(s=>r.has(s)),i=t.size>0&&[...t].every(s=>n.has(s));return o?"dna":i?"rna":"amino"},get colConsensus(){let{colStats:t}=this;return Array.from({length:t.numColumns},(r,n)=>{let o=t.total(n),i=0,s="";t.forEachResidue(n,(c,l)=>{l>i&&(i=l,s=aD(c))});let a=o?i/o:0;return{letter:s,color:a>.4?`hsl(240, 30%, ${100*Math.max(1-a/3,.3)}%)`:void 0}})},get colClustalX(){let{colStats:t}=this;return Array.from({length:t.numColumns},(r,n)=>oD(t,n))},get conservation(){let{colStats:t,sequenceType:r}=this,o=Math.log2(r==="amino"?20:4);return Array.from({length:t.numColumns},(i,s)=>{let a=t.total(s),c=t.gapCount(s),l=a-c,u=0;if(l>0){let d=0;t.forEachResidue(s,(A,f)=>{let g=f/l;d-=g*Math.log2(g)}),u=Math.max(0,1-d/o)*(1-c/a)}return u})},get propertyConservation(){return this.sequenceType==="amino"?PD(this.colStats):[]},get hierarchy(){let t=this.root;gI(t,this.totalHeight,e.treeWidth),t.data.length=0;let r=CI(t),n=r?e.treeWidth/r:0;return EI(t,0,n),Ec(t,o=>{if(o._children){let{min:i,max:s}=yI(o);o.collapsedTipXNear=(o.len??0)+i*n,o.collapsedTipXFar=(o.len??0)+s*n}}),t},get totalHeight(){return Cc(this.root).length*e.rowHeight},get leaves(){return Cc(this.hierarchy)},get maxBranchLength(){return xI(this.hierarchy)},get maxDepthToLeaf(){return bc(this.hierarchy)},get allBranchesLength0(){return pI(this.hierarchy).every(t=>!t.source.data.length)},get showBranchLenEffective(){return this.allBranchesLength0?!1:e.showBranchLen}})).views(e=>({get totalWidth(){return e.numColumns*e.colWidth}})).views(e=>({get dataInitialized(){return(e.data.msa!==""||e.data.tree!=="")&&!e.error},get blocksX(){return ly({viewportSize:e.msaAreaWidth,viewportPos:-e.scrollX,blockSize:e.blockSize,mapSize:e.totalWidth})},get blocksY(){return ly({viewportSize:e.height,viewportPos:-e.scrollY,blockSize:e.blockSize,mapSize:e.totalHeight})}})).views(e=>({get blocks2d(){return e.blocksY.flatMap(t=>e.blocksX.map(r=>[r,t]))},get isLoading(){return e.loadingMSA||e.loadingTree},get maxScrollX(){return Math.min(-e.totalWidth+(e.msaAreaWidth-100),0)},get maxScrollY(){let t=e.height-e.headerHeight-(e.msaAreaWidth<e.totalWidth?e.minimapHeight:0);return Math.min(-e.totalHeight+t,0)},get showMsaLetters(){return e.drawMsaLetters&&e.rowHeight>=5&&e.colWidth>e.rowHeight/2},get showTreeText(){return e.drawLabels&&e.rowHeight>=5}})).actions(e=>({setDrawMsaLetters(t){e.drawMsaLetters=t},setScrollZoom(t){e.scrollZoom=t},setHoveredTreeNode(t){if(t){let r=of(e.hierarchy,n=>n.data.id===t);e.hoveredTreeNode=r?{nodeId:t,descendantNames:Cc(r).map(n=>n.data.name)}:void 0}else e.hoveredTreeNode=void 0},calculateNeighborJoiningTreeFromMSA(){if(e.rows.length<2)throw new Error("Need at least 2 sequences to build a tree");let t=_D(e.rows);e.setTree(t)},resetZoom(){e.setColWidth(12),e.setRowHeight(16)},zoomOutHorizontal(){e.colWidth=Math.max(Yu,Math.floor(e.colWidth*.75)),e.scrollX=(0,rt.clamp)(e.scrollX,e.maxScrollX,0)},zoomInHorizontal(){e.colWidth=Math.min(li,Math.ceil(e.colWidth*1.5)),e.scrollX=(0,rt.clamp)(e.scrollX,e.maxScrollX,0)},zoomInVertical(){e.rowHeight=Math.min(li,Math.ceil(e.rowHeight*1.5))},zoomOutVertical(){e.rowHeight=Math.max(qu,Math.floor(e.rowHeight*.75))},zoomIn(){(0,Rt.transaction)(()=>{this.zoomInHorizontal(),this.zoomInVertical()})},zoomOut(){(0,Rt.transaction)(()=>{this.zoomOutHorizontal(),this.zoomOutVertical()})},zoomToPos(t,r,n){(0,Rt.transaction)(()=>{let o=(-e.scrollX+r)/e.colWidth,i=(-e.scrollY+n)/e.rowHeight;e.colWidth=(0,rt.clamp)(e.colWidth*t,Yu,li),e.rowHeight=(0,rt.clamp)(e.rowHeight*t,qu,li),e.scrollX=(0,rt.clamp)(r-o*e.colWidth,e.maxScrollX,0);let 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numColumns(){return(this.MSA?.getWidth()??0)-this.blanks.length},get tree(){let t=e.data.tree;return t?Aa(xj(t)):this.MSA?.getTree()??{noTree:!0,children:[],id:"empty",name:"empty"}},get rowNames(){return this.leaves.map(t=>t.data.name)},get rowNamesSet(){return new Map(this.leaves.map((t,r)=>[t.data.name,r]))},get mouseOverRowName(){let{mouseRow:t}=e;return t===void 0?void 0:this.leaves[t]?.data.name},get hoveredInsertion(){let{mouseCol:t,mouseRow:r}=e;if(t!==void 0&&r!==void 0){let n=this.leaves[r]?.data.name;if(n){let o=this.insertionPositions.get(n)?.find(i=>i.pos===t);if(o)return{rowName:n,col:t,letters:o.letters}}}},get root(){let t=CI(this.tree,r=>r.children);if(bI(t,r=>r.children.length>0?0:1),EI(t,(r,n)=>(r.data.length??1)-(n.data.length??1)),e.showOnly){let r=Af(t,n=>n.data.id===e.showOnly);r&&(t=r)}for(let r of e.collapsed){let n=Af(t,o=>o.data.id===r);n&&(n.children?SI(n):n.parent?.children&&(n.parent.children=n.parent.children.filter(o=>o.data.id!==r)))}return t},get msaAreaWidth(){return e.width-e.treeAreaWidth-e.resizeHandleWidth},get treeAreaWidthMinusMargin(){return e.treeAreaWidth-e.marginLeft},get blanks(){let{hideGapsEffective:t,realAllowedGappyness:r}=e;if(!t)return[];let n=this.leaves.map(l=>this.MSA?.getRow(l.data.name)).filter(nt.notEmpty);if(n.length===0)return[];let o=n.reduce((l,u)=>Math.max(l,u.length),0),i=n.length,s=Math.ceil(r/100*i),a=new Uint32Array(o);for(let l=0;l<i;l++){let u=n[l],d=u.length;for(let A=0;A<o;A++)(A>=d||u.charCodeAt(A)-45>>>0<=1)&&a[A]++}let c=[];for(let l=0;l<o;l++)a[l]>=s&&c.push(l);return c},get blanksSet(){return new Set(this.blanks)},get insertionPositions(){let{blanks:t,rows:r}=this;if(t.length===0||!e.hideGapsEffective)return new Map;let n=new Map;for(let[o,i]of r){let s=hI(t,i);s.length>0&&n.set(o,s)}return n},get rows(){let t=this.MSA;return this.leaves.map(r=>[r.data.name,t?.getRow(r.data.name)]).filter(r=>!!r[1])},get numRows(){return this.leaves.length},get seqPosGlobalColIndex(){return new Map(this.rows.map(([t,r])=>[t,XD(r)]))},get rowMap(){return new Map(this.rows)},get columns(){let t=this.columns2d;return new Map(this.rows.map((r,n)=>[r[0],t[n]]))},get columns2d(){let{hideGapsEffective:t}=e;return this.rows.map(([,r])=>(t?Jp(this.blanks,r):r).toUpperCase())},get fontSize(){return Math.min(Math.max(6,e.rowHeight-3),18)},get colStats(){return xD(this.columns2d)},get colStatsSums(){return this.colStats.totals},get sequenceType(){let t=this.colStats.lettersPresent,r=new Set(["A","C","G","T","N"]),n=new Set(["A","C","G","U","N"]),o=t.size>0&&[...t].every(s=>r.has(s)),i=t.size>0&&[...t].every(s=>n.has(s));return o?"dna":i?"rna":"amino"},get colConsensus(){let{colStats:t}=this;return Array.from({length:t.numColumns},(r,n)=>{let o=t.total(n),i=0,s="";t.forEachResidue(n,(c,l)=>{l>i&&(i=l,s=gD(c))});let a=o?i/o:0;return{letter:s,color:a>.4?`hsl(240, 30%, ${100*Math.max(1-a/3,.3)}%)`:void 0}})},get colClustalX(){let{colStats:t}=this;return Array.from({length:t.numColumns},(r,n)=>AD(t,n))},get conservation(){let{colStats:t,sequenceType:r}=this,o=Math.log2(r==="amino"?20:4);return Array.from({length:t.numColumns},(i,s)=>{let a=t.total(s),c=t.gapCount(s),l=a-c,u=0;if(l>0){let d=0;t.forEachResidue(s,(A,f)=>{let g=f/l;d-=g*Math.log2(g)}),u=Math.max(0,1-d/o)*(1-c/a)}return u})},get propertyConservation(){return this.sequenceType==="amino"?YD(this.colStats):[]},get hierarchy(){let t=this.root;II(t,this.totalHeight,e.treeWidth),t.data.length=0;let r=TI(t),n=r?e.treeWidth/r:0;return MI(t,0,n),Mc(t,o=>{if(o._children){let{min:i,max:s}=vI(o);o.collapsedTipXNear=(o.len??0)+i*n,o.collapsedTipXFar=(o.len??0)+s*n}}),t},get totalHeight(){return Tc(this.root).length*e.rowHeight},get leaves(){return Tc(this.hierarchy)},get maxBranchLength(){return BI(this.hierarchy)},get maxDepthToLeaf(){return Rc(this.hierarchy)},get allBranchesLength0(){return wI(this.hierarchy).every(t=>!t.source.data.length)},get showBranchLenEffective(){return 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adapterTrackModels(){let{rowHeight:t,MSA:r,hideGapsEffective:n,blanks:o}=e;return(r?.tracks??[]).filter(s=>!!s.data).map(s=>({model:{...s,data:n?Jp(o,s.data):s.data,height:t},ReactComponent:bD}))},get tracks(){let t={model:{id:"conservation",name:"Conservation",height:e.conservationTrackHeight,barColor:"gray"},ReactComponent:yy},r={model:{id:"property-conservation",name:"Property conservation",height:e.conservationTrackHeight,barColor:"#6a51a3"},ReactComponent:yy};return[...this.adapterTrackModels,t,...e.sequenceType==="amino"?[r]:[]]},get turnedOnTracks(){return this.tracks.filter(t=>!e.turnedOffTracks.has(t.model.id))},get showHorizontalScrollbar(){return e.msaAreaWidth<e.totalWidth},visibleColToRowLetter(t,r){let{rowMap:n,blanks:o}=e;return n.get(t)?.[Sy(o,r)]},visibleColToSeqPos(t,r){return JD({rowName:t,visibleCol:r,rowMap:e.rowMap,blanks:e.blanks})},visibleColToSeqPosOneBased(t,r){let n=this.visibleColToSeqPos(t,r);return n!==void 0?n+1:void 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(${x})`}):null,h?kt.default.createElement(Tl.LoadingEllipses,{variant:"h6",message:`Loading available MSAs for (${f.name})`}):null,g?kt.default.createElement("div",null,kt.default.createElement(Tl.SanitizedHTML,{html:f.description}),kt.default.createElement(en,{feature:t,...b})):null):null),kt.default.createElement(no,{submitDisabled:!v||!w?.length,onSubmit:()=>{try{if(v&&w){let R=`${x}_${a[0]}`;MF({newViewTitle:Gi(v),view:o,querySeqName:R,feature:v,data:{msa:w.map(D=>`>${D.get("refName")}
81
+ `),onProgress:l}),E=JSON.stringify(g);return await uN({proteinSequence:c,blastDatabase:r,blastProgram:n,msaAlgorithm:o,msa:y.msa,tree:y.tree,treeMetadata:E,rid:d,geneId:s?.get("parentId"),transcriptId:s?.id(),transcriptName:s?.get("name")??s?.get("id"),geneName:s?.get("gene_name")??s?.get("parentId")}),{...y,treeMetadata:E}}function Lj(e,t){let r={},n=e.taxid?t.get(e.taxid):void 0;return n?.sciname&&(r["Scientific name"]=n.sciname),n?.commonName&&(r["Common name"]=n.commonName),e.accession&&(r.Accession=e.accession),e.id&&(r.ID=e.id),e.title&&(r.Description=e.title),r}var xN="https://api.ncbi.nlm.nih.gov/datasets/v2",Dy="https://eutils.ncbi.nlm.nih.gov/entrez/eutils",Ml=[{label:"Human",taxId:9606},{label:"Mouse",taxId:10090},{label:"Rat",taxId:10116},{label:"Cow",taxId:9913},{label:"Pig",taxId:9823},{label:"Dog",taxId:9615},{label:"Chicken",taxId:9031},{label:"Frog",taxId:8364},{label:"Zebrafish",taxId:7955},{label:"Fruitfly",taxId:7227},{label:"C. elegans",taxId:6239},{label:"Yeast",taxId:4932},{label:"Arabidopsis",taxId:3702}],yN=new Map(Ml.map((e,t)=>[e.taxId,t]));function Rl(e){let t=e.includes("?")?"&":"?";return`${e}${t}tool=${_y}&email=${encodeURIComponent(ky)}`}async function CN(e,t){for(let r of e){let n=r.trim();if(!n)continue;if(/^\d+$/.test(n))return{geneId:n,matched:n};let o=n.replace(/^\w+:/,"").replace(/\.\d+$/,""),i=`${o}[Gene Name] AND ${t}[taxid]`,a=(await Qa(Rl(`${Dy}/esearch.fcgi?db=gene&term=${encodeURIComponent(i)}&retmode=json&retmax=1`))).esearchresult?.idlist?.[0];if(a)return{geneId:a,matched:o}}}async function Pj(e,t){let r=await Qa(Rl(`${xN}/gene/id/${e}/orthologs?returned_content=COMPLETE`)),n=new Map;for(let{gene:o}of r.reports??[]){let i=Number(o?.tax_id);o?.gene_id&&t.has(i)&&!n.has(i)&&n.set(i,{taxId:i,geneId:o.gene_id,scientificName:o.taxname??String(i),commonName:o.common_name})}return[...n.values()].sort((o,i)=>(yN.get(o.taxId)??1/0)-(yN.get(i.taxId)??1/0))}async function bN(e){let t=new Map;if(e.length>0){let r=await Qa(Rl(`${xN}/gene/id/${e.join(",")}/product_report`));for(let{product:n}of r.reports??[]){let o=(n?.transcripts??[]).map(s=>({acc:s.protein?.accession_version,len:s.protein?.length??0,mane:/select/i.test(s.select_category??"")})).filter(s=>!!s.acc),i=o.find(s=>s.mane)??[...o].sort((s,a)=>a.len-s.len).at(0);n?.gene_id&&i&&t.set(n.gene_id,i.acc)}}return t}function EN(e){let t=new Map,r,n=[];for(let o of e.split(`
82
+ `))o.startsWith(">")?(r&&t.set(r,n.join("")),r=o.slice(1).split(/\s+/)[0],n=[]):n.push(o.trim());return r&&t.set(r,n.join("")),t}function Fj(e){return e.replace(/[^A-Za-z0-9]+/g,"_").replace(/^_+|_+$/g,"")}function Oj(e){let t=new Map;return e.map(r=>{let n=Fj(r)||"row",o=t.get(n)??0;return t.set(n,o+1),o===0?n:`${n}_${o+1}`})}async function wN(e){let t=(await bN([e])).get(e);if(!t)return;let r=EN(await zt(Rl(`${Dy}/efetch.fcgi?db=protein&id=${t}&rettype=fasta&retmode=text`))).get(t);return r?{accession:t,sequence:r}:void 0}async function IN({geneId:e,taxa:t,onProgress:r}){r("Finding orthologs across species...");let n=await Pj(e,t);if(n.length<2)throw new Error(`Only ${n.length} ortholog(s) found among the selected species \u2014 not enough to align`);r("Selecting a representative protein per species...");let o=await bN(n.map(u=>u.geneId)),i=n.filter(u=>o.has(u.geneId));if(i.length<2)throw new Error("Could not resolve representative proteins for the orthologs");r(`Fetching ${i.length} protein sequences...`);let s=i.map(u=>o.get(u.geneId)),a=EN(await zt(Rl(`${Dy}/efetch.fcgi?db=protein&id=${s.join(",")}&rettype=fasta&retmode=text`))),c=Oj(i.map(u=>u.commonName??u.scientificName)),l=i.map((u,d)=>{let A=o.get(u.geneId);return{taxId:u.taxId,label:c[d],scientificName:u.scientificName,commonName:u.commonName,geneId:u.geneId,protein:A,sequence:a.get(A)??""}}).filter(u=>u.sequence);if(l.length<2)throw new Error("Could not fetch protein sequences for the orthologs");return l}async function SN({self:e}){let{taxId:t,taxa:r,geneCandidates:n,msaAlgorithm:o,proteinSequence:i}=e.orthologParams,s=Ma(i),a=f=>{e.setProgress(f)};a("Resolving gene at NCBI...");let c=await CN(n,t);if(!c)throw new Error(`Could not resolve any of ${n.join(", ")} to an NCBI gene in taxon ${t}. Try the NCBI BLAST tab, which needs no gene identifier.`);let l=new Set(r.filter(f=>f!==t)),u=await IN({geneId:c.geneId,taxa:l,onProgress:a}),d={QUERY:await Gj(e,c.geneId,s)};for(let f of u)d[f.label]=Uj(f);return{...await mA({algorithm:o,sequence:[`>QUERY
83
+ ${s}`,...u.map(f=>`>${f.label}
84
+ ${f.sequence}`)].join(`
85
+ `),onProgress:a}),treeMetadata:JSON.stringify(d)}}async function Gj(e,t,r){let n=e.orthologParams?.selectedTranscript,o={"Gene ID":t},i=n?.get("name")??n?.get("id");i&&(o.Transcript=i);try{let s=await wN(t);s?.sequence===r&&(o.Accession=s.accession)}catch(s){console.warn("[msaview-orthologs] query protein lookup failed:",s)}return o}function Uj(e){let t={"Scientific name":e.scientificName,Accession:e.protein,"Gene ID":e.geneId};return e.commonName&&(t["Common name"]=e.commonName),t}fh();var BN=p(Ay());async function TN({location:e,name:t}){let r=i=>(0,BN.openLocation)({uri:i,locationType:"UriLocation"}),n=await r(`${e.uri}.idx`).readFile("utf8"),o=Hj(n,t);if(o){let s=await new na({filehandle:r(e.uri),gziFilehandle:r(`${e.uri}.gzi`)}).read(o.length,o.offset);return new TextDecoder().decode(s).trim()}}var vN=e=>e.replace(/\.\d+$/,"");function Hj(e,t){let r=vN(t);for(let n of e.split(`
86
+ `)){let[o,i,s]=n.split(" ");if(o&&vN(o)===r)return{offset:Number(i),length:Number(s)}}}var MN=p(we());function RN({model:e}){let{hovered:t}=(0,MN.getSession)(e),{querySeqName:r,transcriptToMsaMap:n,connectedView:o,mafRegion:i}=e;if(!o?.initialized||!ui(t))return;let{coord:s,refName:a}=t.hoverPosition,c=s-1;if(i)return a!==i.refName||!o.assemblyNames.includes(i.assemblyName)||c<i.start||c>=i.end?void 0:e.seqPosToVisibleCol(r,c-i.start);if(a===n?.refName){let l=n.g2p[c];if(l!==void 0)return e.seqPosToVisibleCol(r,l)}}var Vj="jbrowse-msaview-domain-cache",gA="domains",jj=1,QN=$o(Vj,jj,e=>{e.objectStoreNames.contains(gA)||e.createObjectStore(gA,{keyPath:"accession"})});async function _N(e){let r=(await QN()).transaction(gA,"readonly"),n=await Promise.all(e.map(o=>r.store.get(o)));return await r.done,n}async function kN(e){let r=(await QN()).transaction(gA,"readwrite");for(let n of e)await r.store.put(n);await r.done}function Wo(e,t){return new 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t=new Map,r=/<GBSeq>([\s\S]*?)<\/GBSeq>/g,n;for(;(n=r.exec(e))!==null;){let o=n[1],i=[],s=/<GBFeature>([\s\S]*?)<\/GBFeature>/g,a;for(;(a=s.exec(o))!==null;){let c=qj(a[1]);c&&i.push(c)}for(let c of[Wo(o,"GBSeq_accession-version"),Wo(o,"GBSeq_primary-accession")])c&&t.set(c,i)}return t}async function DN(e){let t=[...new Set(e)].filter(Boolean),r=new Map,n=await _N(t),o=[];t.forEach((a,c)=>{let l=n[c];l?r.set(a,l.matches):o.push(a)});let i=[],s=100;for(let a=0;a<o.length;a+=s){let c=o.slice(a,a+s),l=await zt(pA({db:"protein",id:c.join(","),rettype:"gp",retmode:"xml"})),u=zj(l);for(let d of c){let A=u.get(d);A!==void 0&&(r.set(d,A),i.push({accession:d,matches:A}))}}return i.length>0&&await kN(i),r}async function NN(e){let t=e.data.treeMetadata;if(!t)throw new Error("No sequence metadata available to look up domains");let r=JSON.parse(t),n=Object.entries(r).map(([s,a])=>({rowName:s,accession:a.Accession})).filter(s=>!!s.accession);if(n.length===0)throw new Error("No NCBI accessions found 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84
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  ${D.get("seq")}`).join(`
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- `)}}),r()}}catch(R){l(R)}},onCancel:r}))}),DF=F7;var NF=p(_());function Ml({children:e,value:t,index:r,...n}){return NF.default.createElement("div",{role:"tabpanel",hidden:t!==r,...n},t===r?e:null)}function ux({handleClose:e,feature:t,model:r}){let n=(0,FF.getSession)(r),i=!!LA(n.jbrowse)?.length,[s,a]=(0,Xt.useState)("ncbi_blast");return Xt.default.createElement(LF.Dialog,{maxWidth:"xl",title:"Launch MSA view",open:!0,onClose:e},Xt.default.createElement(_a.Tabs,{value:s,onChange:(c,l)=>{a(l)}},Xt.default.createElement(_a.Tab,{label:"NCBI BLAST query",value:"ncbi_blast"}),i?Xt.default.createElement(_a.Tab,{label:"Pre-loaded MSA datasets",value:"preloaded_msa"}):null,Xt.default.createElement(_a.Tab,{label:"Manual upload",value:"manual_msa"})),Xt.default.createElement(Ml,{value:s,index:"ncbi_blast"},Xt.default.createElement(ax,{handleClose:e,feature:t,model:r})),i?Xt.default.createElement(Ml,{value:s,index:"preloaded_msa"},Xt.default.createElement(DF,{model:r,feature:t,handleClose:e})):null,Xt.default.createElement(Ml,{value:s,index:"manual_msa"},Xt.default.createElement(VL,{model:r,feature:t,handleClose:e})))}function P7(e){return e.name==="LinearBasicDisplay"}var O7=new Set(["gene","mRNA","transcript"]);function G7(e){return e.views(t=>{let r=t.contextMenuItems;return{contextMenuItems(){let n=(0,PA.getContainingTrack)(t),o=(0,PA.getSession)(n),i=u=>{o.queueDialog(d=>[ux,{model:n,handleClose:d,feature:u}])},s=t.contextMenuInfo,a=t.fetchFullFeature,c=t.contextMenuFeature,l=s&&a&&t.isGeneLike?()=>{a(s.item.featureId,s.displayedRegionIndex).then(u=>{u?i(u):o.notify("Could not load feature for MSA view","warning")}).catch(u=>{o.notifyError(`${u}`,u)})}:c&&O7.has(String(c.get("type")))?()=>{i(c)}:void 0;return[...r(),...l?[{label:"Launch MSA view",icon:rL,onClick:l}]:[]]}}})}function fx(e){e.addToExtensionPoint("Core-extendPluggableElement",t=>(P7(t)&&(t.stateModel=G7(t.stateModel)),t))}function dx(e){e.addToExtensionPoint("LaunchView-MsaView",t=>{let{session:r,data:n,msaFileLocation:o,msaIndexedLocation:i,msaName:s,treeFileLocation:a,querySeqName:c,...l}=t;if(!n&&!o&&!i)throw new Error("No MSA data or file location provided when launching MSA view");return r.addView("MsaView",{type:"MsaView",...l,data:n,...a?{treeFilehandle:{...a,locationType:"UriLocation"}}:{},init:{msaUrl:o?.uri,msaIndexedLocation:i,msaName:s,querySeqName:c}}),t})}var eP=p(_()),tP=p(OF());var q7=(0,eP.lazy)(()=>Promise.resolve().then(()=>(ZF(),XF)));function gx(e){e.addViewType(()=>new tP.default({name:"MsaView",stateModel:Ty(),ReactComponent:q7}))}var rP="2.7.3";var UA=class extends nP.default{constructor(){super(...arguments);this.name="MsaViewPlugin";this.version=rP;this.rootConfigurationSchema=r=>({msa:(0,hx.ConfigurationSchema)("MSA",{datasets:yx.types.maybe(yx.types.array((0,hx.ConfigurationSchema)("MSAEntry",{datasetId:{type:"string",defaultValue:""},description:{type:"string",defaultValue:""},name:{type:"string",defaultValue:""},adapter:r.pluggableConfigSchemaType("adapter")})))})})}install(r){gx(r),fx(r),dx(r),_y(r),Dy(r)}configure(r){(0,oP.isAbstractMenuManager)(r.rootModel)&&r.rootModel.appendToSubMenu(["Add"],{label:"Multiple sequence alignment view",icon:vw,onClick:n=>{n.addView("MsaView",{})}})}};return vP(z7);})();
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+ `)}}),r()}}catch(R){l(R)}},onCancel:r}))}),tF=u$;var rF=p(Q());function Ga({children:e,value:t,index:r,...n}){return rF.default.createElement("div",{role:"tabpanel",hidden:t!==r,...n},t===r?e:null)}function yx({handleClose:e,feature:t,model:r}){let n=(0,oF.getSession)(r),i=!!UA(n.jbrowse)?.length,[s,a]=(0,wt.useState)("orthologs");return wt.default.createElement(nF.Dialog,{maxWidth:"xl",title:"Launch MSA view",open:!0,onClose:e},wt.default.createElement(qi.Tabs,{value:s,onChange:(c,l)=>{a(l)}},wt.default.createElement(qi.Tab,{label:"Orthologs (fast)",value:"orthologs"}),wt.default.createElement(qi.Tab,{label:"NCBI BLAST query",value:"ncbi_blast"}),i?wt.default.createElement(qi.Tab,{label:"Pre-loaded MSA datasets",value:"preloaded_msa"}):null,wt.default.createElement(qi.Tab,{label:"Manual upload",value:"manual_msa"})),wt.default.createElement(Ga,{value:s,index:"orthologs"},wt.default.createElement(VP,{handleClose:e,feature:t,model:r})),wt.default.createElement(Ga,{value:s,index:"ncbi_blast"},wt.default.createElement(px,{handleClose:e,feature:t,model:r})),i?wt.default.createElement(Ga,{value:s,index:"preloaded_msa"},wt.default.createElement(tF,{model:r,feature:t,handleClose:e})):null,wt.default.createElement(Ga,{value:s,index:"manual_msa"},wt.default.createElement(iP,{model:r,feature:t,handleClose:e})))}function f$(e){return e.name==="LinearBasicDisplay"}var d$=new Set(["gene","mRNA","transcript"]);function A$(e){return e.views(t=>{let r=t.contextMenuItems;return{contextMenuItems(){let n=(0,VA.getContainingTrack)(t),o=(0,VA.getSession)(n),i=u=>{o.queueDialog(d=>[yx,{model:n,handleClose:d,feature:u}])},s=t.contextMenuInfo,a=t.fetchFullFeature,c=t.contextMenuFeature,l=s&&a&&t.isGeneLike?()=>{a(s.item.featureId,s.displayedRegionIndex).then(u=>{u?i(u):o.notify("Could not load feature for MSA view","warning")}).catch(u=>{o.notifyError(`${u}`,u)})}:c&&d$.has(String(c.get("type")))?()=>{i(c)}:void 0;return[...r(),...l?[{label:"Launch MSA view",icon:yL,onClick:l}]:[]]}}})}function xx(e){e.addToExtensionPoint("Core-extendPluggableElement",t=>(f$(t)&&(t.stateModel=A$(t.stateModel)),t))}function Cx(e){e.addToExtensionPoint("LaunchView-MsaView",t=>{let{session:r,data:n,msaFileLocation:o,msaIndexedLocation:i,msaName:s,treeFileLocation:a,querySeqName:c,...l}=t;if(!n&&!o&&!i)throw new Error("No MSA data or file location provided when launching MSA view");return r.addView("MsaView",{type:"MsaView",...l,data:n,...a?{treeFilehandle:{...a,locationType:"UriLocation"}}:{},init:{msaUrl:o?.uri,msaIndexedLocation:i,msaName:s,querySeqName:c}}),t})}var bF=p(Q()),EF=p(sF());var b$=(0,bF.lazy)(()=>Promise.resolve().then(()=>(CF(),xF)));function Ix(e){e.addViewType(()=>new EF.default({name:"MsaView",stateModel:Ly(),ReactComponent:b$}))}var wF="2.7.4";var WA=class extends IF.default{constructor(){super(...arguments);this.name="MsaViewPlugin";this.version=wF;this.rootConfigurationSchema=r=>({msa:(0,Sx.ConfigurationSchema)("MSA",{datasets:vx.types.maybe(vx.types.array((0,Sx.ConfigurationSchema)("MSAEntry",{datasetId:{type:"string",defaultValue:""},description:{type:"string",defaultValue:""},name:{type:"string",defaultValue:""},adapter:r.pluggableConfigSchemaType("adapter")})))})})}install(r){Ix(r),xx(r),Cx(r),Gy(r),Hy(r)}configure(r){(0,SF.isAbstractMenuManager)(r.rootModel)&&r.rootModel.appendToSubMenu(["Add"],{label:"Multiple sequence alignment view",icon:Dw,onClick:n=>{n.addView("MsaView",{})}})}};return YF(E$);})();
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  react-is/cjs/react-is.production.js: