jbrowse-plugin-msaview 2.7.0 → 2.7.2

package/dist/jbrowse-plugin-msaview.umd.production.min.js

@@ -1,11 +1,20 @@
-"use strict";var JBrowsePluginMsaView=(()=>{var p_=Object.create;var _s=Object.defineProperty;var g_=Object.getOwnPropertyDescriptor;var h_=Object.getOwnPropertyNames;var C_=Object.getPrototypeOf,E_=Object.prototype.hasOwnProperty;var p=(e,t,r)=>()=>{if(r)throw r[0];try{return e&&(t=e(e=0)),t}catch(n){throw r=[n],n}};var V=(e,t)=>()=>{try{return t||e((t={exports:{}}).exports,t),t.exports}catch(r){throw t=0,r}},dt=(e,t)=>{for(var r in t)_s(e,r,{get:t[r],enumerable:!0})},lg=(e,t,r,n)=>{if(t&&typeof t=="object"||typeof t=="function")for(let o of h_(t))!E_.call(e,o)&&o!==r&&_s(e,o,{get:()=>t[o],enumerable:!(n=g_(t,o))||n.enumerable});return e};var f=(e,t,r)=>(r=e!=null?p_(C_(e)):{},lg(t||!e||!e.__esModule?_s(r,"default",{value:e,enumerable:!0}):r,e)),I_=e=>lg(_s({},"__esModule",{value:!0}),e);var ug=V((W3,Ag)=>{Ag.exports=JBrowseExports["@jbrowse/core/Plugin"]});var Jo=V(($3,fg)=>{fg.exports=JBrowseExports["@jbrowse/core/configuration"]});var de=V((K3,dg)=>{dg.exports=JBrowseExports["@jbrowse/core/util"]});var Pt=V((X3,mg)=>{mg.exports=JBrowseExports["mobx-state-tree"]});var gg=V((Z3,pg)=>{pg.exports=JBrowseExports["@mui/material/SvgIcon"]});var j,me=p(()=>{"use client";j=f(gg(),1)});var R=V((tP,hg)=>{hg.exports=JBrowseExports["react/jsx-runtime"]});var M=V((oP,Ig)=>{Ig.exports=JBrowseExports.react});var H=V((iP,xg)=>{xg.exports=JBrowseExports["mobx-react"]});var wt=V((aP,yg)=>{yg.exports=JBrowseExports["tss-react/mui"]});var YA=V((AP,Bg)=>{Bg.exports=JBrowseExports["@jbrowse/core/pluggableElementTypes"]});var Vo=V((fP,Qg)=>{Qg.exports=JBrowseExports.mobx});function ks(e){let{scrollX:t,msaAreaWidth:r,minimapHeight:n,colWidth:o,numColumns:i}=e,a=r/i/o,s=-t,c=s*a,l=(s+r)*a,A=Math.max(l-c,20),u=n-12,m=`${c+A},0 ${c},0 0,${u} ${r},${u}`;return{unit:a,s:c,w:A,polygonHeight:u,polygonPoints:m}}var zA=p(()=>{});var eo,vg,x_,Mg,_g=p(()=>{eo=f(M(),1),vg=f(H(),1);zA();x_=(0,vg.observer)(({model:e})=>{let{msaAreaWidth:t}=e,{s:r,w:n,polygonPoints:o}=ks(e),i="rgb(66, 119, 127)",a=.3;return eo.default.createElement(eo.default.Fragment,null,eo.default.createElement("rect",{x:0,y:0,width:t,height:12,stroke:"#555",fill:"none"}),eo.default.createElement("rect",{x:Math.max(0,r),y:0,width:n,height:12,fill:i,fillOpacity:a,stroke:"#555"}),eo.default.createElement("g",{transform:`translate(0 ${12})`},eo.default.createElement("polygon",{fill:i,fillOpacity:a,points:o})))}),Mg=x_});function Ds({model:e,offsetY:t,blockSizeY:r}){let{leaves:n,rowHeight:o}=e,i=Math.max(0,Math.floor((t-o)/o)),a=Math.max(0,Math.ceil((t+r+o)/o));return n.slice(i,a)}var WA=p(()=>{});var $A,KA,Tg,kg,Ns,Ls,to,Dg,Rs,Ng,Lg,Rg,Fg,Pg,Og,Gg,Ug,aa=p(()=>{$A=new Set(["exon","CDS","five_prime_UTR","three_prime_UTR","UTR","intron"]),KA=["#9fb6d4","#d4dcea"],Tg=!0,kg=!1,Ns=.2,Ls=1,to=80,Dg=!0,Rs="maeditor",Ng=!0,Lg=!0,Rg=!1,Fg=400,Pg=300,Og=!0,Gg=!0,Ug=!0});function Fs({model:e,offsetX:t,offsetY:r,ctx:n,highResScaleFactorOverride:o,blockSizeYOverride:i}){let{blockSize:a,rowHeight:s,highResScaleFactor:c,showDomains:l}=e;if(l){let A=o??c,u=i??a;n.resetTransform(),n.scale(A,A),n.translate(-t,s/2-r);let m=Ds({model:e,offsetY:r,blockSizeY:u});w_({model:e,ctx:n,visibleLeaves:m})}}function w_({model:e,ctx:t,visibleLeaves:r}){let{subFeatureRows:n,colWidth:o,rowHeight:i,fillPalette:a,strokePalette:s,segmentLabels:c,showMsaLetters:l,tidyFilteredGatheredInterProAnnotations:A}=e,u=n?4:i,m=!l&&!n&&u>=9;for(let d=0,g=r.length;d<g;d++){let C=r[d],{name:y}=C.data,I=C.x,E=A[y];if(E)for(let b=0,x=E.length;b<x;b++){let{start:w,end:Q,accession:S,strand:k}=E[b],N=e.seqPosToVisibleCol(y,w-1),_=e.seqPosToVisibleCol(y,Q);if(N!==void 0&&_!==void 0){let v=N*o,L=I-i+(n?b*u:0),U=o*(_-N);if(t.fillStyle=a[S],t.strokeStyle=s[S],k===void 0){t.fillRect(v,L,U,u),t.strokeRect(v,L,U,u);let W=m?c.get(S):void 0;if(W!==void 0&&d===0){let se=Math.min(u-2,11);t.font=`${se}px sans-serif`,t.measureText(W).width+2<=U&&(t.fillStyle="#222",t.textAlign="center",t.textBaseline="middle",t.fillText(W,v+U/2,L+u/2))}}else b_({ctx:t,x:v,t:L,w:U,h:u,strand:k})}}}}function b_({ctx:e,x:t,t:r,w:n,h:o,strand:i}){let a=i>0?1:-1,s=i>0?t:t+n,c=i>0?t+n:t;e.beginPath(),e.moveTo(s,r),e.lineTo(c,r),e.lineTo(c+a*o,r+o/2),e.lineTo(c,r+o),e.lineTo(s,r+o),e.closePath(),e.fill(),e.stroke()}var XA=p(()=>{WA();aa()});function sa({offsetX:e,blockWidth:t,colWidth:r}){return{xStart:Math.max(0,Math.floor(e/r)),xEnd:Math.max(0,Math.ceil((e+t)/r))}}var ZA=p(()=>{});function kr(e,t,r=!1){e.font=e.font.replace(/(?:bold )?[\d.]+px/,`${r?"bold ":""}${t}px`)}var zo=p(()=>{});var B_,Zr,We,Kt,Wg,Hg,eu,S_,Ps,$g,Kg,jg,qg,Jg,ca,Q_,v_,M_,__,nu,Vg,T_,tu,ru,Yg,ou,Je,zg,Os,la=p(()=>{B_={grad:.9,turn:360,rad:360/(2*Math.PI)},Zr=function(e){return typeof e=="string"?e.length>0:typeof e=="number"},We=function(e,t,r){return t===void 0&&(t=0),r===void 0&&(r=Math.pow(10,t)),Math.round(r*e)/r+0},Kt=function(e,t,r){return t===void 0&&(t=0),r===void 0&&(r=1),e>r?r:e>t?e:t},Wg=function(e){return(e=isFinite(e)?e%360:0)>0?e:e+360},Hg=function(e){return{r:Kt(e.r,0,255),g:Kt(e.g,0,255),b:Kt(e.b,0,255),a:Kt(e.a)}},eu=function(e){return{r:We(e.r),g:We(e.g),b:We(e.b),a:We(e.a,3)}},S_=/^#([0-9a-f]{3,8})$/i,Ps=function(e){var t=e.toString(16);return t.length<2?"0"+t:t},$g=function(e){var t=e.r,r=e.g,n=e.b,o=e.a,i=Math.max(t,r,n),a=i-Math.min(t,r,n),s=a?i===t?(r-n)/a:i===r?2+(n-t)/a:4+(t-r)/a:0;return{h:60*(s<0?s+6:s),s:i?a/i*100:0,v:i/255*100,a:o}},Kg=function(e){var t=e.h,r=e.s,n=e.v,o=e.a;t=t/360*6,r/=100,n/=100;var i=Math.floor(t),a=n*(1-r),s=n*(1-(t-i)*r),c=n*(1-(1-t+i)*r),l=i%6;return{r:255*[n,s,a,a,c,n][l],g:255*[c,n,n,s,a,a][l],b:255*[a,a,c,n,n,s][l],a:o}},jg=function(e){return{h:Wg(e.h),s:Kt(e.s,0,100),l:Kt(e.l,0,100),a:Kt(e.a)}},qg=function(e){return{h:We(e.h),s:We(e.s),l:We(e.l),a:We(e.a,3)}},Jg=function(e){return Kg((r=(t=e).s,{h:t.h,s:(r*=((n=t.l)<50?n:100-n)/100)>0?2*r/(n+r)*100:0,v:n+r,a:t.a}));var t,r,n},ca=function(e){return{h:(t=$g(e)).h,s:(o=(200-(r=t.s))*(n=t.v)/100)>0&&o<200?r*n/100/(o<=100?o:200-o)*100:0,l:o/2,a:t.a};var t,r,n,o},Q_=/^hsla?\(\s*([+-]?\d*\.?\d+)(deg|rad|grad|turn)?\s*,\s*([+-]?\d*\.?\d+)%\s*,\s*([+-]?\d*\.?\d+)%\s*(?:,\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,v_=/^hsla?\(\s*([+-]?\d*\.?\d+)(deg|rad|grad|turn)?\s+([+-]?\d*\.?\d+)%\s+([+-]?\d*\.?\d+)%\s*(?:\/\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,M_=/^rgba?\(\s*([+-]?\d*\.?\d+)(%)?\s*,\s*([+-]?\d*\.?\d+)(%)?\s*,\s*([+-]?\d*\.?\d+)(%)?\s*(?:,\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,__=/^rgba?\(\s*([+-]?\d*\.?\d+)(%)?\s+([+-]?\d*\.?\d+)(%)?\s+([+-]?\d*\.?\d+)(%)?\s*(?:\/\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,nu={string:[[function(e){var t=S_.exec(e);return t?(e=t[1]).length<=4?{r:parseInt(e[0]+e[0],16),g:parseInt(e[1]+e[1],16),b:parseInt(e[2]+e[2],16),a:e.length===4?We(parseInt(e[3]+e[3],16)/255,2):1}:e.length===6||e.length===8?{r:parseInt(e.substr(0,2),16),g:parseInt(e.substr(2,2),16),b:parseInt(e.substr(4,2),16),a:e.length===8?We(parseInt(e.substr(6,2),16)/255,2):1}:null:null},"hex"],[function(e){var t=M_.exec(e)||__.exec(e);return t?t[2]!==t[4]||t[4]!==t[6]?null:Hg({r:Number(t[1])/(t[2]?100/255:1),g:Number(t[3])/(t[4]?100/255:1),b:Number(t[5])/(t[6]?100/255:1),a:t[7]===void 0?1:Number(t[7])/(t[8]?100:1)}):null},"rgb"],[function(e){var t=Q_.exec(e)||v_.exec(e);if(!t)return null;var r,n,o=jg({h:(r=t[1],n=t[2],n===void 0&&(n="deg"),Number(r)*(B_[n]||1)),s:Number(t[3]),l:Number(t[4]),a:t[5]===void 0?1:Number(t[5])/(t[6]?100:1)});return Jg(o)},"hsl"]],object:[[function(e){var t=e.r,r=e.g,n=e.b,o=e.a,i=o===void 0?1:o;return Zr(t)&&Zr(r)&&Zr(n)?Hg({r:Number(t),g:Number(r),b:Number(n),a:Number(i)}):null},"rgb"],[function(e){var t=e.h,r=e.s,n=e.l,o=e.a,i=o===void 0?1:o;if(!Zr(t)||!Zr(r)||!Zr(n))return null;var a=jg({h:Number(t),s:Number(r),l:Number(n),a:Number(i)});return Jg(a)},"hsl"],[function(e){var t=e.h,r=e.s,n=e.v,o=e.a,i=o===void 0?1:o;if(!Zr(t)||!Zr(r)||!Zr(n))return null;var a=(function(s){return{h:Wg(s.h),s:Kt(s.s,0,100),v:Kt(s.v,0,100),a:Kt(s.a)}})({h:Number(t),s:Number(r),v:Number(n),a:Number(i)});return Kg(a)},"hsv"]]},Vg=function(e,t){for(var r=0;r<t.length;r++){var n=t[r][0](e);if(n)return[n,t[r][1]]}return[null,void 0]},T_=function(e){return typeof e=="string"?Vg(e.trim(),nu.string):typeof e=="object"&&e!==null?Vg(e,nu.object):[null,void 0]},tu=function(e,t){var r=ca(e);return{h:r.h,s:Kt(r.s+100*t,0,100),l:r.l,a:r.a}},ru=function(e){return(299*e.r+587*e.g+114*e.b)/1e3/255},Yg=function(e,t){var r=ca(e);return{h:r.h,s:r.s,l:Kt(r.l+100*t,0,100),a:r.a}},ou=(function(){function e(t){this.parsed=T_(t)[0],this.rgba=this.parsed||{r:0,g:0,b:0,a:1}}return e.prototype.isValid=function(){return this.parsed!==null},e.prototype.brightness=function(){return We(ru(this.rgba),2)},e.prototype.isDark=function(){return ru(this.rgba)<.5},e.prototype.isLight=function(){return ru(this.rgba)>=.5},e.prototype.toHex=function(){return t=eu(this.rgba),r=t.r,n=t.g,o=t.b,a=(i=t.a)<1?Ps(We(255*i)):"","#"+Ps(r)+Ps(n)+Ps(o)+a;var t,r,n,o,i,a},e.prototype.toRgb=function(){return eu(this.rgba)},e.prototype.toRgbString=function(){return t=eu(this.rgba),r=t.r,n=t.g,o=t.b,(i=t.a)<1?"rgba("+r+", "+n+", "+o+", "+i+")":"rgb("+r+", "+n+", "+o+")";var t,r,n,o,i},e.prototype.toHsl=function(){return qg(ca(this.rgba))},e.prototype.toHslString=function(){return t=qg(ca(this.rgba)),r=t.h,n=t.s,o=t.l,(i=t.a)<1?"hsla("+r+", "+n+"%, "+o+"%, "+i+")":"hsl("+r+", "+n+"%, "+o+"%)";var t,r,n,o,i},e.prototype.toHsv=function(){return t=$g(this.rgba),{h:We(t.h),s:We(t.s),v:We(t.v),a:We(t.a,3)};var t},e.prototype.invert=function(){return Je({r:255-(t=this.rgba).r,g:255-t.g,b:255-t.b,a:t.a});var t},e.prototype.saturate=function(t){return t===void 0&&(t=.1),Je(tu(this.rgba,t))},e.prototype.desaturate=function(t){return t===void 0&&(t=.1),Je(tu(this.rgba,-t))},e.prototype.grayscale=function(){return Je(tu(this.rgba,-1))},e.prototype.lighten=function(t){return t===void 0&&(t=.1),Je(Yg(this.rgba,t))},e.prototype.darken=function(t){return t===void 0&&(t=.1),Je(Yg(this.rgba,-t))},e.prototype.rotate=function(t){return t===void 0&&(t=15),this.hue(this.hue()+t)},e.prototype.alpha=function(t){return typeof t=="number"?Je({r:(r=this.rgba).r,g:r.g,b:r.b,a:t}):We(this.rgba.a,3);var r},e.prototype.hue=function(t){var r=ca(this.rgba);return typeof t=="number"?Je({h:t,s:r.s,l:r.l,a:r.a}):We(r.h)},e.prototype.isEqual=function(t){return this.toHex()===Je(t).toHex()},e})(),Je=function(e){return e instanceof ou?e:new ou(e)},zg=[],Os=function(e){e.forEach(function(t){zg.indexOf(t)<0&&(t(ou,nu),zg.push(t))})}});function Xg(e){e.prototype.luminance=function(){return t=au(this.rgba),(r=2)===void 0&&(r=0),n===void 0&&(n=Math.pow(10,r)),Math.round(n*t)/n+0;var t,r,n},e.prototype.contrast=function(t){t===void 0&&(t="#FFF");var r,n,o,i,a,s,c,l=t instanceof e?t:new e(t);return i=this.rgba,a=l.toRgb(),s=au(i),c=au(a),r=s>c?(s+.05)/(c+.05):(c+.05)/(s+.05),(n=2)===void 0&&(n=0),o===void 0&&(o=Math.pow(10,n)),Math.floor(o*r)/o+0},e.prototype.isReadable=function(t,r){return t===void 0&&(t="#FFF"),r===void 0&&(r={}),this.contrast(t)>=(s=(a=(n=r).size)===void 0?"normal":a,(i=(o=n.level)===void 0?"AA":o)==="AAA"&&s==="normal"?7:i==="AA"&&s==="large"?3:4.5);var n,o,i,a,s}}var iu,au,Zg=p(()=>{iu=function(e){var t=e/255;return t<.04045?t/12.92:Math.pow((t+.055)/1.055,2.4)},au=function(e){return .2126*iu(e.r)+.7152*iu(e.g)+.0722*iu(e.b)}});function Gs(e,t){var r={white:"#ffffff",bisque:"#ffe4c4",blue:"#0000ff",cadetblue:"#5f9ea0",chartreuse:"#7fff00",chocolate:"#d2691e",coral:"#ff7f50",antiquewhite:"#faebd7",aqua:"#00ffff",azure:"#f0ffff",whitesmoke:"#f5f5f5",papayawhip:"#ffefd5",plum:"#dda0dd",blanchedalmond:"#ffebcd",black:"#000000",gold:"#ffd700",goldenrod:"#daa520",gainsboro:"#dcdcdc",cornsilk:"#fff8dc",cornflowerblue:"#6495ed",burlywood:"#deb887",aquamarine:"#7fffd4",beige:"#f5f5dc",crimson:"#dc143c",cyan:"#00ffff",darkblue:"#00008b",darkcyan:"#008b8b",darkgoldenrod:"#b8860b",darkkhaki:"#bdb76b",darkgray:"#a9a9a9",darkgreen:"#006400",darkgrey:"#a9a9a9",peachpuff:"#ffdab9",darkmagenta:"#8b008b",darkred:"#8b0000",darkorchid:"#9932cc",darkorange:"#ff8c00",darkslateblue:"#483d8b",gray:"#808080",darkslategray:"#2f4f4f",darkslategrey:"#2f4f4f",deeppink:"#ff1493",deepskyblue:"#00bfff",wheat:"#f5deb3",firebrick:"#b22222",floralwhite:"#fffaf0",ghostwhite:"#f8f8ff",darkviolet:"#9400d3",magenta:"#ff00ff",green:"#008000",dodgerblue:"#1e90ff",grey:"#808080",honeydew:"#f0fff0",hotpink:"#ff69b4",blueviolet:"#8a2be2",forestgreen:"#228b22",lawngreen:"#7cfc00",indianred:"#cd5c5c",indigo:"#4b0082",fuchsia:"#ff00ff",brown:"#a52a2a",maroon:"#800000",mediumblue:"#0000cd",lightcoral:"#f08080",darkturquoise:"#00ced1",lightcyan:"#e0ffff",ivory:"#fffff0",lightyellow:"#ffffe0",lightsalmon:"#ffa07a",lightseagreen:"#20b2aa",linen:"#faf0e6",mediumaquamarine:"#66cdaa",lemonchiffon:"#fffacd",lime:"#00ff00",khaki:"#f0e68c",mediumseagreen:"#3cb371",limegreen:"#32cd32",mediumspringgreen:"#00fa9a",lightskyblue:"#87cefa",lightblue:"#add8e6",midnightblue:"#191970",lightpink:"#ffb6c1",mistyrose:"#ffe4e1",moccasin:"#ffe4b5",mintcream:"#f5fffa",lightslategray:"#778899",lightslategrey:"#778899",navajowhite:"#ffdead",navy:"#000080",mediumvioletred:"#c71585",powderblue:"#b0e0e6",palegoldenrod:"#eee8aa",oldlace:"#fdf5e6",paleturquoise:"#afeeee",mediumturquoise:"#48d1cc",mediumorchid:"#ba55d3",rebeccapurple:"#663399",lightsteelblue:"#b0c4de",mediumslateblue:"#7b68ee",thistle:"#d8bfd8",tan:"#d2b48c",orchid:"#da70d6",mediumpurple:"#9370db",purple:"#800080",pink:"#ffc0cb",skyblue:"#87ceeb",springgreen:"#00ff7f",palegreen:"#98fb98",red:"#ff0000",yellow:"#ffff00",slateblue:"#6a5acd",lavenderblush:"#fff0f5",peru:"#cd853f",palevioletred:"#db7093",violet:"#ee82ee",teal:"#008080",slategray:"#708090",slategrey:"#708090",aliceblue:"#f0f8ff",darkseagreen:"#8fbc8f",darkolivegreen:"#556b2f",greenyellow:"#adff2f",seagreen:"#2e8b57",seashell:"#fff5ee",tomato:"#ff6347",silver:"#c0c0c0",sienna:"#a0522d",lavender:"#e6e6fa",lightgreen:"#90ee90",orange:"#ffa500",orangered:"#ff4500",steelblue:"#4682b4",royalblue:"#4169e1",turquoise:"#40e0d0",yellowgreen:"#9acd32",salmon:"#fa8072",saddlebrown:"#8b4513",sandybrown:"#f4a460",rosybrown:"#bc8f8f",darksalmon:"#e9967a",lightgoldenrodyellow:"#fafad2",snow:"#fffafa",lightgrey:"#d3d3d3",lightgray:"#d3d3d3",dimgray:"#696969",dimgrey:"#696969",olivedrab:"#6b8e23",olive:"#808000"},n={};for(var o in r)n[r[o]]=o;var i={};e.prototype.toName=function(a){if(!(this.rgba.a||this.rgba.r||this.rgba.g||this.rgba.b))return"transparent";var s,c,l=n[this.toHex()];if(l)return l;if(a?.closest){var A=this.toRgb(),u=1/0,m="black";if(!i.length)for(var d in r)i[d]=new e(r[d]).toRgb();for(var g in r){var C=(s=A,c=i[g],Math.pow(s.r-c.r,2)+Math.pow(s.g-c.g,2)+Math.pow(s.b-c.b,2));C<u&&(u=C,m=g)}return m}},t.string.push([function(a){var s=a.toLowerCase(),c=s==="transparent"?"#0000":r[s];return c?new e(c).toRgb():null},"name"])}var su=p(()=>{});function th(e,t){let r=`${e}|${t}`,n=eh.get(r);if(n!==void 0)return n;let o=Je(e);if(!o.isReadable(t)){let a=Je(t).luminance()<.5;for(let s=0;s<40&&!o.isReadable(t);s++)o=a?o.lighten(.05):o.darken(.05)}let i=o.toHex();return eh.set(r,i),i}function Wo(e,t){return Object.fromEntries(Object.entries(e).map(t))}function Aa(e,t){return Wo(e,([r,n])=>[r,t.palette.getContrastText(Je(n).toHex())])}function cu(e,t){if(e.length===0)return t;let r=[],n=0;for(let o of e)o>n&&r.push(t.slice(n,o)),n=o+1;return n<t.length&&r.push(t.slice(n)),r.join("")}function rh(e,t){let r=[],n=e.length,o=0,i=0,a=-1,s=[];for(let c=0;c<t.length;c++)i<n&&e[i]===c?(t.charCodeAt(c)-45>>>0<=1||(a===o?s.push(t[c]):(s.length>0&&r.push({pos:a,letters:s.join("")}),a=o,s=[t[c]])),i++):o++;return s.length>0&&r.push({pos:a,letters:s.join("")}),r}function lu(e){return e.end-e.start}function ua(e){return e==="-"||e==="."}var eh,xn=p(()=>{la();Zg();su();Os([Gs,Xg]);eh=new Map});function Us({model:e,offsetX:t,offsetY:r,contrastScheme:n,ctx:o,theme:i,highResScaleFactorOverride:a,blockSizeXOverride:s,blockSizeYOverride:c}){let{colWidth:l,blockSize:A,rowHeight:u,fontSize:m,highResScaleFactor:d,actuallyShowDomains:g,bgColor:C}=e,y=a??d,I=s??A,E=c??A;o.resetTransform(),o.scale(y,y),o.translate(-t,u/2-r),o.textAlign="center",o.textBaseline="alphabetic",kr(o,m,!C);let{xStart:b,xEnd:x}=sa({offsetX:t,blockWidth:I,colWidth:l}),w=Ds({model:e,offsetY:r,blockSizeY:E}),{relativeTo:Q,columns:S}=e,k=Q?S.get(Q)?.slice(b,x):null;g?D_({model:e,ctx:o,xStart:b,xEnd:x,visibleLeaves:w,referenceSeq:k}):k_({model:e,ctx:o,theme:i,contrastScheme:n,xStart:b,xEnd:x,visibleLeaves:w,referenceSeq:k}),N_({model:e,ctx:o,xStart:b,xEnd:x,visibleLeaves:w}),o.resetTransform()}function k_({model:e,ctx:t,theme:r,contrastScheme:n,visibleLeaves:o,xStart:i,xEnd:a,referenceSeq:s}){let{bgColor:c,colorSchemeName:l,colorScheme:A,columns:u,colWidth:m,rowHeight:d,relativeTo:g,showMsaLetters:C,colClustalX:y,colConsensus:I}=e,E=l==="clustalx_protein_dynamic",b=l==="percent_identity_dynamic";if(!c&&!C)return;let x=i*m,w=m/2,Q=d/4;for(let S=0,k=o.length;S<k;S++){let N=o[S],{name:_}=N.data,v=N.x,L=u.get(_)?.slice(i,a);if(!L)continue;let U=v-d,W=v-Q;for(let se=0,Te=L.length;se<Te;se++){let Oe=L[se],pn=se*m+x,Kn=s&&_!==g&&Oe===s[se],It;if(E)It=y[i+se][Oe];else if(b){let Ae=I[i+se];It=Oe===Ae.letter?Ae.color:void 0}else It=A[Oe];c&&(t.fillStyle=Kn?r.palette.action.hover:It||r.palette.background.default,t.fillRect(pn,U,m,d)),C&&(t.fillStyle=c?n[Oe]??"black":It?th(It,r.palette.background.default):r.palette.text.primary,t.fillText(Kn?".":Oe,pn+w,W))}}}function D_({model:e,ctx:t,visibleLeaves:r,xStart:n,xEnd:o,referenceSeq:i}){let{showMsaLetters:a,columns:s,colWidth:c,rowHeight:l,relativeTo:A}=e;if(!a)return;let u=n*c,m=c/2,d=l/4;t.fillStyle="black";for(let g=0,C=r.length;g<C;g++){let y=r[g],{name:I}=y.data,E=y.x-d,b=s.get(I)?.slice(n,o);if(b)for(let x=0,w=b.length;x<w;x++){let Q=b[x],S=i&&I!==A&&Q===i[x];t.fillText(S?".":Q,x*c+u+m,E)}}}function N_({model:e,ctx:t,visibleLeaves:r,xStart:n,xEnd:o}){let{bgColor:i,hideGapsEffective:a}=e;a&&(t.lineWidth=1,t.strokeStyle="#f0f",nh({visibleLeaves:r,xStart:n,ctx:t,model:e,xEnd:o,offset:0}),t.strokeStyle=i?"#fff":"#000",nh({visibleLeaves:r,xStart:n,ctx:t,model:e,xEnd:o,offset:-1}))}function nh({model:e,ctx:t,visibleLeaves:r,xStart:n,xEnd:o,offset:i}){let{colWidth:s,rowHeight:c,insertionPositions:l}=e;for(let A of r){let{name:u}=A.data,m=l.get(u);if(m){let d=A.x;for(let{pos:g}of m)if(g>=n&&g<o){let C=g*s,y=d-c,I=d;t.beginPath(),t.moveTo(C+i,y+i);let E=y,b=!0;for(;E<I;){let x=Math.min(E+2,I),w=b?C+1:C-1;t.lineTo(w+i,x+i),E=x,b=!b}t.stroke()}}}}var Au=p(()=>{WA();ZA();zo();xn()});function uu({ctx:e,values:t,color:r,colWidth:n,trackHeight:o,offsetX:i,blockSize:a}){let{xStart:s,xEnd:c}=sa({offsetX:i,blockWidth:a,colWidth:n});e.fillStyle=r;for(let l=s;l<c&&l<t.length;l++){let u=t[l]*o,m=l*n;e.fillRect(m,o-u,n,u)}}function fu(e,t){return t==="property-conservation"?e.propertyConservation:e.conservation}function du({ctx:e,data:t,colorScheme:r,contrastScheme:n,bgColor:o,colWidth:i,rowHeight:a,offsetX:s,blockSize:c}){let{xStart:l,xEnd:A}=sa({offsetX:s,blockWidth:c,colWidth:i}),u=t?.slice(l,A);for(let m=0;u&&m<u.length;m++){let d=u[m],g=d.toUpperCase();if(o){let C=(l+m)*i;e.fillStyle=r[g]||"white",e.fillRect(C,0,i,a),a>=10&&i>=a/2&&(e.fillStyle=n[g]||"black",e.fillText(d,C+i/2,a/2+1))}}}function L_({model:e,ctx:t,track:r,offsetX:n,offsetY:o,trackHeight:i,blockSizeXOverride:a,highResScaleFactorOverride:s}){let{blockSize:c,colWidth:l,highResScaleFactor:A}=e,u=a??c,m=s??A;t.resetTransform(),t.scale(m,m),t.translate(-n,o),uu({ctx:t,values:fu(e,r.model.id),color:r.model.barColor??"gray",colWidth:l,trackHeight:i,offsetX:n,blockSize:u}),t.resetTransform()}function R_({model:e,ctx:t,track:r,offsetX:n,offsetY:o,contrastScheme:i,blockSizeXOverride:a,highResScaleFactorOverride:s}){let{blockSize:c,bgColor:l,colorScheme:A,colWidth:u,fontSize:m,rowHeight:d,highResScaleFactor:g}=e,{customColorScheme:C,data:y}=r.model,I=C??A,E=a??c,b=s??g;t.resetTransform(),t.scale(b,b),t.translate(-n,o),t.textAlign="center",kr(t,m),du({ctx:t,data:y,colorScheme:I,contrastScheme:i,bgColor:l,colWidth:u,rowHeight:d,offsetX:n,blockSize:E}),t.resetTransform()}function oh({model:e,ctx:t,offsetX:r,contrastScheme:n,blockSizeXOverride:o,highResScaleFactorOverride:i}){let{turnedOnTracks:a}=e,s=0;for(let c of a){let l=c.model.height;c.model.barColor!==void 0?L_({model:e,ctx:t,track:c,offsetX:r,offsetY:s,trackHeight:l,blockSizeXOverride:o,highResScaleFactorOverride:i}):R_({model:e,ctx:t,track:c,offsetX:r,offsetY:s,contrastScheme:n,blockSizeXOverride:o,highResScaleFactorOverride:i}),s+=l}}var Hs=p(()=>{zo();ZA()});function ro(e){let t=[],r=[e];for(;r.length>0;){let n=r.pop();if(t.push(n),n.children)for(let o=n.children.length-1;o>=0;o--)r.push(n.children[o])}return t}function F_(e){let t=ro(e);for(let r=t.length-1;r>=0;r--){let n=t[r],o=0;if(n.children)for(let i of n.children)i.height+1>o&&(o=i.height+1);n.height=o}}function ih(e,t){let r={data:e,children:null,parent:null,depth:0,height:0},n=[r];for(;n.length>0;){let o=n.pop(),i=t(o.data);if(i?.length){o.children=i.map(a=>({data:a,children:null,parent:o,depth:o.depth+1,height:0}));for(let a of o.children)n.push(a)}}return F_(r),r}function ah(e,t){let r=ro(e);for(let n=r.length-1;n>=0;n--){let o=r[n],i=t(o.data);if(o.children)for(let a of o.children)i+=a.value;o.value=i}return e}function sh(e,t){let r=[e];for(;r.length>0;){let n=r.pop();if(n.children){n.children.sort(t);for(let o of n.children)r.push(o)}}return e}function js(e,t){let r=[e],n;for(;r.length>0&&n===void 0;){let o=r.pop();if(t(o))n=o;else if(o.children)for(let i=o.children.length-1;i>=0;i--)r.push(o.children[i])}return n}function fa(e){let t=[],r=[e];for(;r.length>0;){let n=r.pop();if(n.children)for(let o=n.children.length-1;o>=0;o--)r.push(n.children[o]);else t.push(n)}return t}function ch(e){let t=[];return mu(e,(r,n)=>{t.push({source:r,target:n})}),t}function mu(e,t){let r=[e];for(;r.length>0;){let n=r.pop();if(n.children)for(let o=n.children.length-1;o>=0;o--){let i=n.children[o];t(n,i),r.push(i)}}}function da(e,t){for(let r of ro(e))t(r)}function lh(e,t,r){let n=fa(e),o=n.length,i=t/o;for(let l=0;l<o;l++)n[l].x=(l+.5)*i;let a=ro(e);for(let l=a.length-1;l>=0;l--){let A=a[l];if(A.children){let u=0;for(let m of A.children)u+=m.x;A.x=u/A.children.length}}let s=e.height,c=[{node:e,depth:0}];for(;c.length>0;){let{node:l,depth:A}=c.pop();if(l.y=s===0?r:A/s*r,l.children)for(let u of l.children)c.push({node:u,depth:A+1})}}function Ah(e){e.children&&(ma(e),e._children=e.children,e.children=null)}function uh(e){let t=e._children??e.children,r=1/0,n=0;if(t){let o=t.map(i=>({node:i,acc:Math.max(i.data.length??0,0)}));for(;o.length>0;){let{node:i,acc:a}=o.pop(),s=i.children??i._children;if(s?.length)for(let c of s)o.push({node:c,acc:a+Math.max(c.data.length??0,0)});else r=Math.min(r,a),n=Math.max(n,a)}}return{min:r===1/0?0:r,max:n}}function ma(e){let t=ro(e);for(let r=t.length-1;r>=0;r--){let n=t[r];if(n.depthToLeaf===void 0){let o=0;if(n.children)for(let i of n.children)o=Math.max(o,1+i.depthToLeaf);n.depthToLeaf=o}}return e.depthToLeaf}function fh(e){let t=0;for(let r of ro(e))t=Math.max(t,r.len||0);return t}function dh(e){let t=ro(e),r=new Map;for(let n=t.length-1;n>=0;n--){let o=t[n],i=0;if(o.children)for(let a of o.children)i=Math.max(i,r.get(a));r.set(o,(o.data.length||0)+i)}return r.get(e)}function mh(e,t,r){let n=[{node:e,y0:t}];for(;n.length>0;){let{node:o,y0:i}=n.pop(),a=i+Math.max(o.data.length||0,0);if(o.len=a*r,o.children)for(let s of o.children)n.push({node:s,y0:a})}}var pu=p(()=>{});function hu(e,t,r){return e>t-ph&&e<t+r+ph}function pa(e,t,r,n){if(t)return e.len;if(n===0)return 0;let o=ma(e);return(n-o)/n*r}function P_({offsetY:e,ctx:t,model:r,theme:n,maxBranchLen:o,maxDepthToLeaf:i,blockSizeYOverride:a}){let{hierarchy:s,showBranchLenEffective:c,blockSize:l}=r,A=a??l;t.strokeStyle=n.palette.text.primary,mu(s,(u,m)=>{let d=u.x,g=m.x,C=pa(m,c,o,i),y=pa(u,c,o,i);if(C===void 0||y===void 0)return;let I=Math.min(d,g),E=Math.max(d,g);e+A>=I&&E>=e&&(t.beginPath(),t.moveTo(y,d),t.lineTo(y,g),t.lineTo(C,g),t.stroke())})}function O_({ctx:e,clickMap:t,offsetY:r,model:n,theme:o,maxBranchLen:i,maxDepthToLeaf:a,blockSizeYOverride:s}){let{hierarchy:c,showBranchLenEffective:l,collapsed:A,blockSize:u,rowHeight:m,fontSize:d,marginLeft:g}=n,C=s??u,y=Math.max(2,m*.42);da(c,I=>{let{id:E,name:b}=I.data;if(A.includes(E)){let x=pa(I,l,i,a),w=I.x,Q=hu(w,r,C),S=l?I.collapsedTipXFar??i:i;if(x!==void 0&&Q&&S>x){e.beginPath(),e.moveTo(x,w),e.lineTo(S,w-y),e.lineTo(S,w+y),e.closePath(),e.fillStyle=o.palette.action.disabled,e.fill(),e.strokeStyle=o.palette.text.primary,e.stroke();let k=I.value;k!==void 0&&m>=8&&(e.fillStyle=o.palette.text.primary,e.textAlign="left",e.fillText(`${k}`,S+3,w+d/4));let N=b===E?"Collapsed clade":b;t?.insert({minX:x+g,maxX:S+g,minY:w-y,maxY:w+y,branch:!0,id:E,name:k===void 0?N:`${N} (${k} tips)`})}}})}function G_({ctx:e,clickMap:t,offsetY:r,model:n,maxBranchLen:o,maxDepthToLeaf:i,blockSizeYOverride:a}){let{hierarchy:s,showBranchLenEffective:c,collapsed:l,blockSize:A,marginLeft:u}=n,m=a??A;da(s,d=>{let g=pa(d,c,o,i);if(g===void 0)return;let{data:C}=d,y=d.x,{id:I,name:E}=C;if(d.height>=1&&hu(y,r,m)){let b=l.includes(I);e.strokeStyle="black",e.fillStyle=b?"black":"white",e.beginPath(),e.arc(g,y,no,0,2*Math.PI),e.fill(),e.stroke(),b||t?.insert({minX:g-no+u,maxX:g-no+gu+u,minY:y-no,maxY:y-no+gu,branch:!0,id:I,name:E})}})}function U_({theme:e,model:t,offsetY:r,ctx:n,clickMap:o,maxBranchLen:i,maxDepthToLeaf:a,blockSizeYOverride:s}){let{fontSize:c,showBranchLenEffective:l,treeMetadata:A,blockSize:u,labelsAlignRight:m,drawTree:d,treeAreaWidth:g,treeAreaWidthMinusMargin:C,marginLeft:y,leaves:I,noTree:E,labelWidthMap:b,collapsed:x}=t,w=s??u,Q=n.measureText("M").width;m?(n.textAlign="right",n.setLineDash([1,3])):n.textAlign="start";for(let S of I){let{data:{name:k,id:N}}=S,_=S.x,v=A[k]?.genome||k;if(!(x.includes(N)&&k===N)&&hu(_,r,w)){let U=_+c/4,W=0;E||(W=pa(S,l,i,a)??0);let se=b.get(k)??n.measureText(v).width;if(n.fillStyle=e.palette.text.primary,m){let Oe=C-2;d&&!E&&(n.moveTo(W+no+2,_),n.lineTo(Oe-2-se,_),n.stroke()),n.fillText(v,Oe,U),o?.insert({minX:g-se,maxX:g,minY:U-Q,maxY:U,name:k,id:N})}else{let Te=E?2:W+gu;n.fillText(v,Te,U),o?.insert({minX:Te+y,maxX:Te+se+y,minY:U-Q,maxY:U,name:k,id:N})}}}n.setLineDash([])}function qs({model:e,clickMap:t,ctx:r,offsetY:n,theme:o,highResScaleFactorOverride:i,blockSizeYOverride:a}){t?.clear();let{noTree:s,drawTree:c,drawNodeBubbles:l,highResScaleFactor:A,fontSize:u,showTreeText:m,marginLeft:d,rowHeight:g}=e;r.resetTransform();let C=i??A;r.scale(C,C),r.translate(d,-n),kr(r,u);let{maxBranchLength:y,maxDepthToLeaf:I}=e;!s&&c&&(P_({ctx:r,offsetY:n,model:e,theme:o,maxBranchLen:y,maxDepthToLeaf:I,blockSizeYOverride:a}),O_({ctx:r,clickMap:t,offsetY:n,model:e,theme:o,maxBranchLen:y,maxDepthToLeaf:I,blockSizeYOverride:a}),l&&G_({ctx:r,offsetY:n,clickMap:t,model:e,maxBranchLen:y,maxDepthToLeaf:I,blockSizeYOverride:a})),m&&U_({ctx:r,offsetY:n,model:e,clickMap:t,theme:o,maxBranchLen:y,maxDepthToLeaf:I,blockSizeYOverride:a}),t?.finish()}var ga,ph,no,gu,Js=p(()=>{pu();zo();ga=600,ph=5,no=2.5,gu=no*2});var Ch={};dt(Ch,{Context:()=>Iu});function gh(e){return!e||typeof e=="string"?e:e+""}function mr(e,t){let r=Object.keys(t);for(let n of r)e=e.replace(new RegExp("\\{"+n+"\\}","gi"),t[n]);return e}function Cu(e){if(!e)throw new Error("cannot create a random attribute name for an undefined object");let t="ABCDEFGHIJKLMNOPQRSTUVWXTZabcdefghiklmnopqrstuvwxyz",r="";do{r="";for(let n=0;n<12;n++)r+=t[Math.floor(Math.random()*t.length)]}while(e[r]);return r}function H_(e,t=10){let r={},n=e.split(",");for(let o=0;o<n.length;o+=2){let i="&"+n[o+1]+";",a=parseInt(n[o],t);r[i]="&#"+a+";"}return r["\\xa0"]="&#160;",r}function j_(e){let t={left:"start",right:"end",center:"middle",start:"start",end:"end"};return t[e]||t.start}function q_(e){let t={alphabetic:"alphabetic",hanging:"hanging",top:"text-before-edge",bottom:"text-after-edge",middle:"central"};return t[e]||t.alphabetic}var hh,ha,Ca,Eu,Iu,Eh=p(()=>{hh=H_("50,nbsp,51,iexcl,52,cent,53,pound,54,curren,55,yen,56,brvbar,57,sect,58,uml,59,copy,5a,ordf,5b,laquo,5c,not,5d,shy,5e,reg,5f,macr,5g,deg,5h,plusmn,5i,sup2,5j,sup3,5k,acute,5l,micro,5m,para,5n,middot,5o,cedil,5p,sup1,5q,ordm,5r,raquo,5s,frac14,5t,frac12,5u,frac34,5v,iquest,60,Agrave,61,Aacute,62,Acirc,63,Atilde,64,Auml,65,Aring,66,AElig,67,Ccedil,68,Egrave,69,Eacute,6a,Ecirc,6b,Euml,6c,Igrave,6d,Iacute,6e,Icirc,6f,Iuml,6g,ETH,6h,Ntilde,6i,Ograve,6j,Oacute,6k,Ocirc,6l,Otilde,6m,Ouml,6n,times,6o,Oslash,6p,Ugrave,6q,Uacute,6r,Ucirc,6s,Uuml,6t,Yacute,6u,THORN,6v,szlig,70,agrave,71,aacute,72,acirc,73,atilde,74,auml,75,aring,76,aelig,77,ccedil,78,egrave,79,eacute,7a,ecirc,7b,euml,7c,igrave,7d,iacute,7e,icirc,7f,iuml,7g,eth,7h,ntilde,7i,ograve,7j,oacute,7k,ocirc,7l,otilde,7m,ouml,7n,divide,7o,oslash,7p,ugrave,7q,uacute,7r,ucirc,7s,uuml,7t,yacute,7u,thorn,7v,yuml,ci,fnof,sh,Alpha,si,Beta,sj,Gamma,sk,Delta,sl,Epsilon,sm,Zeta,sn,Eta,so,Theta,sp,Iota,sq,Kappa,sr,Lambda,ss,Mu,st,Nu,su,Xi,sv,Omicron,t0,Pi,t1,Rho,t3,Sigma,t4,Tau,t5,Upsilon,t6,Phi,t7,Chi,t8,Psi,t9,Omega,th,alpha,ti,beta,tj,gamma,tk,delta,tl,epsilon,tm,zeta,tn,eta,to,theta,tp,iota,tq,kappa,tr,lambda,ts,mu,tt,nu,tu,xi,tv,omicron,u0,pi,u1,rho,u2,sigmaf,u3,sigma,u4,tau,u5,upsilon,u6,phi,u7,chi,u8,psi,u9,omega,uh,thetasym,ui,upsih,um,piv,812,bull,816,hellip,81i,prime,81j,Prime,81u,oline,824,frasl,88o,weierp,88h,image,88s,real,892,trade,89l,alefsym,8cg,larr,8ch,uarr,8ci,rarr,8cj,darr,8ck,harr,8dl,crarr,8eg,lArr,8eh,uArr,8ei,rArr,8ej,dArr,8ek,hArr,8g0,forall,8g2,part,8g3,exist,8g5,empty,8g7,nabla,8g8,isin,8g9,notin,8gb,ni,8gf,prod,8gh,sum,8gi,minus,8gn,lowast,8gq,radic,8gt,prop,8gu,infin,8h0,ang,8h7,and,8h8,or,8h9,cap,8ha,cup,8hb,int,8hk,there4,8hs,sim,8i5,cong,8i8,asymp,8j0,ne,8j1,equiv,8j4,le,8j5,ge,8k2,sub,8k3,sup,8k4,nsub,8k6,sube,8k7,supe,8kl,oplus,8kn,otimes,8l5,perp,8m5,sdot,8o8,lceil,8o9,rceil,8oa,lfloor,8ob,rfloor,8p9,lang,8pa,rang,9ea,loz,9j0,spades,9j3,clubs,9j5,hearts,9j6,diams,ai,OElig,aj,oelig,b0,Scaron,b1,scaron,bo,Yuml,m6,circ,ms,tilde,802,ensp,803,emsp,809,thinsp,80c,zwnj,80d,zwj,80e,lrm,80f,rlm,80j,ndash,80k,mdash,80o,lsquo,80p,rsquo,80q,sbquo,80s,ldquo,80t,rdquo,80u,bdquo,810,dagger,811,Dagger,81g,permil,81p,lsaquo,81q,rsaquo,85c,euro",32),ha={strokeStyle:{svgAttr:"stroke",canvas:"#000000",svg:"none",apply:"stroke"},fillStyle:{svgAttr:"fill",canvas:"#000000",svg:null,apply:"fill"},lineCap:{svgAttr:"stroke-linecap",canvas:"butt",svg:"butt",apply:"stroke"},lineJoin:{svgAttr:"stroke-linejoin",canvas:"miter",svg:"miter",apply:"stroke"},miterLimit:{svgAttr:"stroke-miterlimit",canvas:10,svg:4,apply:"stroke"},lineWidth:{svgAttr:"stroke-width",canvas:1,svg:1,apply:"stroke"},globalAlpha:{svgAttr:"opacity",canvas:1,svg:1,apply:"fill stroke"},font:{canvas:"10px sans-serif"},shadowColor:{canvas:"#000000"},shadowOffsetX:{canvas:0},shadowOffsetY:{canvas:0},shadowBlur:{canvas:0},textAlign:{canvas:"start"},textBaseline:{canvas:"alphabetic"},lineDash:{svgAttr:"stroke-dasharray",canvas:[],svg:null,apply:"stroke"}},Ca=class{__root;__ctx;constructor(t,r){this.__root=t,this.__ctx=r}addColorStop(t,r){let n=this.__ctx.__createElement("stop");if(n.setAttribute("offset",String(t)),gh(r).includes("rgba")){let i=/rgba\(\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d?\.?\d*)\s*\)/gi.exec(r);i&&(n.setAttribute("stop-color",mr("rgb({r},{g},{b})",{r:i[1],g:i[2],b:i[3]})),n.setAttribute("stop-opacity",i[4]))}else n.setAttribute("stop-color",gh(r));this.__root.appendChild(n)}},Eu=class{__root;__ctx;constructor(t,r){this.__root=t,this.__ctx=r}},Iu=class{width;height;enableMirroring;canvas;__document;__ctx;__canvas;__root;__ids;__defs;__currentElement;__styleStack;__groupStack;__currentDefaultPath;__currentPosition;__transformMatrix;__transformMatrixStack;__currentElementsToStyle;__options;__id;__fontUnderline;__fontHref;strokeStyle;fillStyle;lineCap;lineJoin;miterLimit;lineWidth;globalAlpha;font;shadowColor;shadowOffsetX;shadowOffsetY;shadowBlur;textAlign;textBaseline;lineDash;constructor(t,r){let n={width:500,height:500,enableMirroring:!1},o;typeof t=="number"&&r!==void 0?o={...n,width:t,height:r}:t&&typeof t=="object"?o=t:o=n,this.width=o.width||n.width,this.height=o.height||n.height,this.enableMirroring=o.enableMirroring!==void 0?o.enableMirroring:n.enableMirroring,this.canvas=this,this.__document=o.document||document,o.ctx?this.__ctx=o.ctx:(this.__canvas=this.__document.createElement("canvas"),this.__ctx=this.__canvas.getContext("2d")),this.__setDefaultStyles(),this.__styleStack=[this.__getStyleState()],this.__groupStack=[],this.__root=this.__document.createElementNS("http://www.w3.org/2000/svg","svg"),this.__root.setAttribute("version","1.1"),this.__root.setAttribute("xmlns","http://www.w3.org/2000/svg"),this.__root.setAttributeNS("http://www.w3.org/2000/xmlns/","xmlns:xlink","http://www.w3.org/1999/xlink"),this.__root.setAttribute("width",String(this.width)),this.__root.setAttribute("height",String(this.height)),this.__ids={},this.__defs=this.__document.createElementNS("http://www.w3.org/2000/svg","defs"),this.__root.appendChild(this.__defs),this.__currentElement=this.__document.createElementNS("http://www.w3.org/2000/svg","g"),this.__root.appendChild(this.__currentElement),this.__currentDefaultPath="",this.__currentPosition={},this.__transformMatrix=new DOMMatrix,this.resetTransform(),this.__options=o,this.__id=Math.random().toString(16).substring(2,8)}__createElement(t,r={},n){let o=this.__document.createElementNS("http://www.w3.org/2000/svg",t);n&&(o.setAttribute("fill","none"),o.setAttribute("stroke","none"));for(let i of Object.keys(r))o.setAttribute(i,r[i]);return o}__setDefaultStyles(){for(let t of Object.keys(ha))this[t]=ha[t].canvas}__applyStyleState(t){for(let r of Object.keys(t))this[r]=t[r]}__getStyleState(){let t={};for(let r of Object.keys(ha))t[r]=this[r];return t}__applyTransformation(t,r){let{a:n,b:o,c:i,d:a,e:s,f:c}=r||this.getTransform();t.setAttribute("transform",`matrix(${n} ${o} ${i} ${a} ${s} ${c})`)}__applyStyleToCurrentElement(t){let r=this.__currentElement,n=this.__currentElementsToStyle;if(n){r.setAttribute(t,""),r=n.element;for(let i of n.children)i.setAttribute(t,"")}let o=Object.keys(ha);for(let i of o){let a=ha[i],s=this[i];if(a.apply){if(s instanceof Eu){if(s.__ctx)for(let c of Array.from(s.__ctx.__defs.childNodes)){let l=c.getAttribute("id");l&&(this.__ids[l]=l,this.__defs.appendChild(c))}r.setAttribute(a.apply,mr("url(#{id})",{id:s.__root.getAttribute("id")}))}else if(s instanceof Ca)r.setAttribute(a.apply,mr("url(#{id})",{id:s.__root.getAttribute("id")}));else if(a.apply.includes(t)&&a.svg!==s)if((a.svgAttr==="stroke"||a.svgAttr==="fill")&&s&&s.includes("rgba")){let l=/rgba\(\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d?\.?\d*)\s*\)/gi.exec(s);if(l){r.setAttribute(a.svgAttr,mr("rgb({r},{g},{b})",{r:l[1],g:l[2],b:l[3]}));let A=Number(l[4]),u=this.globalAlpha;u!=null&&(A*=u),r.setAttribute(a.svgAttr+"-opacity",String(A))}}else{let c=a.svgAttr,l=s;if(i==="globalAlpha"){if(c=t+"-"+a.svgAttr,r.getAttribute(c))continue}else if(i==="lineWidth"){let A=this.__getTransformScale();l=s*Math.max(A.x,A.y)}r.setAttribute(c,l)}}}}__closestGroupOrSvg(t){return t=t||this.__currentElement,t.nodeName==="g"||t.nodeName==="svg"?t:this.__closestGroupOrSvg(t.parentNode)}getSerializedSvg(t){let r=new XMLSerializer().serializeToString(this.__root);if(/xmlns="http:\/\/www\.w3\.org\/2000\/svg".+xmlns="http:\/\/www\.w3\.org\/2000\/svg/gi.test(r)&&(r=r.replace('xmlns="http://www.w3.org/2000/svg','xmlns:xlink="http://www.w3.org/1999/xlink')),t)for(let o of Object.keys(hh)){let i=new RegExp(o,"gi");i.test(r)&&(r=r.replace(i,hh[o]))}return r}getSvg(){return this.__root}save(){let t=this.__createElement("g"),r=this.__closestGroupOrSvg();this.__groupStack.push(r),r.appendChild(t),this.__currentElement=t;let n=this.__getStyleState();this.__styleStack.push(n),this.__transformMatrixStack||(this.__transformMatrixStack=[]),this.__transformMatrixStack.push(this.getTransform())}restore(){this.__currentElement=this.__groupStack.pop(),this.__currentElementsToStyle=void 0,this.__currentElement||(this.__currentElement=this.__root.childNodes[1]);let t=this.__styleStack.pop();this.__applyStyleState(t),this.__transformMatrixStack&&this.__transformMatrixStack.length>0&&this.setTransform(this.__transformMatrixStack.pop())}beginPath(){this.__currentDefaultPath="",this.__currentPosition={};let t=this.__createElement("path",{},!0);this.__closestGroupOrSvg().appendChild(t),this.__currentElement=t}__applyCurrentDefaultPath(){let t=this.__currentElement;t.nodeName==="path"&&t.setAttribute("d",this.__currentDefaultPath)}__addPathCommand(t){this.__currentDefaultPath+=" ",this.__currentDefaultPath+=t}moveTo(t,r){this.__currentElement.nodeName!=="path"&&this.beginPath(),this.__currentPosition={x:t,y:r},this.__addPathCommand(mr("M {x} {y}",{x:this.__matrixTransform(t,r).x,y:this.__matrixTransform(t,r).y}))}closePath(){this.__currentDefaultPath&&this.__addPathCommand("Z")}lineTo(t,r){this.__currentPosition={x:t,y:r},this.__currentDefaultPath.includes("M")?this.__addPathCommand(mr("L {x} {y}",{x:this.__matrixTransform(t,r).x,y:this.__matrixTransform(t,r).y})):this.__addPathCommand(mr("M {x} {y}",{x:this.__matrixTransform(t,r).x,y:this.__matrixTransform(t,r).y}))}bezierCurveTo(t,r,n,o,i,a){this.__currentPosition={x:i,y:a},this.__addPathCommand(mr("C {cp1x} {cp1y} {cp2x} {cp2y} {x} {y}",{cp1x:this.__matrixTransform(t,r).x,cp1y:this.__matrixTransform(t,r).y,cp2x:this.__matrixTransform(n,o).x,cp2y:this.__matrixTransform(n,o).y,x:this.__matrixTransform(i,a).x,y:this.__matrixTransform(i,a).y}))}quadraticCurveTo(t,r,n,o){this.__currentPosition={x:n,y:o},this.__addPathCommand(mr("Q {cpx} {cpy} {x} {y}",{cpx:this.__matrixTransform(t,r).x,cpy:this.__matrixTransform(t,r).y,x:this.__matrixTransform(n,o).x,y:this.__matrixTransform(n,o).y}))}stroke(){this.__currentElement.nodeName==="path"&&this.__currentElement.setAttribute("paint-order","fill stroke markers"),this.__applyCurrentDefaultPath(),this.__applyStyleToCurrentElement("stroke")}fill(){this.__currentElement.nodeName==="path"&&this.__currentElement.setAttribute("paint-order","stroke fill markers"),this.__applyCurrentDefaultPath(),this.__applyStyleToCurrentElement("fill")}rect(t,r,n,o){this.__currentElement.nodeName!=="path"&&this.beginPath(),this.moveTo(t,r),this.lineTo(t+n,r),this.lineTo(t+n,r+o),this.lineTo(t,r+o),this.lineTo(t,r),this.closePath()}__clearCanvas(){let t=this.__root.childNodes[1];this.__root.removeChild(t),this.__currentElement=this.__document.createElementNS("http://www.w3.org/2000/svg","g"),this.__root.appendChild(this.__currentElement),this.__groupStack=[]}fillRect(t,r,n,o){let{a:i,b:a,c:s,d:c,e:l,f:A}=this.getTransform();JSON.stringify([i,a,s,c,l,A])===JSON.stringify([1,0,0,1,0,0])&&t===0&&r===0&&n===this.width&&o===this.height&&this.__clearCanvas();let u=this.__createElement("rect",{x:t,y:r,width:n,height:o},!0);this.__closestGroupOrSvg().appendChild(u),this.__currentElement=u,this.__applyTransformation(u),this.__applyStyleToCurrentElement("fill")}strokeRect(t,r,n,o){let i=this.__createElement("rect",{x:t,y:r,width:n,height:o},!0);this.__closestGroupOrSvg().appendChild(i),this.__currentElement=i,this.__applyTransformation(i),this.__applyStyleToCurrentElement("stroke")}clearRect(t,r,n,o){let{a:i,b:a,c:s,d:c,e:l,f:A}=this.getTransform();if(JSON.stringify([i,a,s,c,l,A])===JSON.stringify([1,0,0,1,0,0])&&t===0&&r===0&&n===this.width&&o===this.height){this.__clearCanvas();return}let u=this.__createElement("rect",{x:t,y:r,width:n,height:o,fill:"#FFFFFF"},!0);this.__applyTransformation(u),this.__closestGroupOrSvg().appendChild(u)}createLinearGradient(t,r,n,o){let i=this.__createElement("linearGradient",{id:Cu(this.__ids),x1:t+"px",x2:n+"px",y1:r+"px",y2:o+"px",gradientUnits:"userSpaceOnUse"});return this.__defs.appendChild(i),new Ca(i,this)}createRadialGradient(t,r,n,o,i,a){let s=this.__createElement("radialGradient",{id:Cu(this.__ids),cx:o+"px",cy:i+"px",r:a+"px",fx:t+"px",fy:r+"px",gradientUnits:"userSpaceOnUse"});return this.__defs.appendChild(s),new Ca(s,this)}__applyText(t,r,n,o){let i=document.createElement("span");i.setAttribute("style","font:"+this.font);let a=i.style,s=this.__closestGroupOrSvg(),c=this.__createElement("text",{"font-family":a.fontFamily,"font-size":a.fontSize,"font-style":a.fontStyle,"font-weight":a.fontWeight,"text-decoration":this.__fontUnderline,x:r,y:n,"text-anchor":j_(this.textAlign),"dominant-baseline":q_(this.textBaseline)},!0);c.appendChild(this.__document.createTextNode(t)),this.__currentElement=c,this.__applyTransformation(c),this.__applyStyleToCurrentElement(o);let l=c;if(this.__fontHref){let A=this.__createElement("a");A.setAttributeNS("http://www.w3.org/1999/xlink","xlink:href",this.__fontHref),A.appendChild(c),l=A}s.appendChild(l)}fillText(t,r,n){this.__applyText(t,r,n,"fill")}strokeText(t,r,n){this.__applyText(t,r,n,"stroke")}measureText(t){return this.__ctx.font=this.font,this.__ctx.measureText(t)}arc(t,r,n,o,i,a){if(o===i)return;o=o%(2*Math.PI),i=i%(2*Math.PI),o===i&&(i=(i+2*Math.PI-.001*(a?-1:1))%(2*Math.PI));let s=t+n*Math.cos(i),c=r+n*Math.sin(i),l=t+n*Math.cos(o),A=r+n*Math.sin(o),u=a?0:1,m=0,d=i-o;d<0&&(d+=2*Math.PI),a?m=d>Math.PI?0:1:m=d>Math.PI?1:0;let g=Math.hypot(this.__transformMatrix.a,this.__transformMatrix.b),C=Math.hypot(this.__transformMatrix.c,this.__transformMatrix.d);this.lineTo(l,A),this.__addPathCommand(mr("A {rx} {ry} {xAxisRotation} {largeArcFlag} {sweepFlag} {endX} {endY}",{rx:n*g,ry:n*C,xAxisRotation:0,largeArcFlag:m,sweepFlag:u,endX:this.__matrixTransform(s,c).x,endY:this.__matrixTransform(s,c).y})),this.__currentPosition={x:s,y:c}}clip(){let t=this.__closestGroupOrSvg(),r=this.__createElement("clipPath"),n=Cu(this.__ids),o=this.__createElement("g");this.__applyCurrentDefaultPath(),t.removeChild(this.__currentElement),r.setAttribute("id",n),r.appendChild(this.__currentElement),this.__defs.appendChild(r),t.setAttribute("clip-path",mr("url(#{id})",{id:n})),t.appendChild(o),this.__currentElement=o}setLineDash(t){t&&t.length>0?this.lineDash=t.join(","):this.lineDash=null}setTransform(t,r,n,o,i,a){t instanceof DOMMatrix?this.__transformMatrix=new DOMMatrix([t.a,t.b,t.c,t.d,t.e,t.f]):this.__transformMatrix=new DOMMatrix([t,r,n,o,i,a])}getTransform(){let{a:t,b:r,c:n,d:o,e:i,f:a}=this.__transformMatrix;return new DOMMatrix([t,r,n,o,i,a])}resetTransform(){this.setTransform(1,0,0,1,0,0)}scale(t,r){if(r===void 0&&(r=t),isNaN(t)||isNaN(r)||!isFinite(t)||!isFinite(r))return;let n=this.getTransform().scale(t,r);this.setTransform(n)}rotate(t){let r=this.getTransform().multiply(new DOMMatrix([Math.cos(t),Math.sin(t),-Math.sin(t),Math.cos(t),0,0]));this.setTransform(r)}translate(t,r){let n=this.getTransform().translate(t,r);this.setTransform(n)}transform(t,r,n,o,i,a){let s=this.getTransform().multiply(new DOMMatrix([t,r,n,o,i,a]));this.setTransform(s)}__matrixTransform(t,r){return new DOMPoint(t,r).matrixTransform(this.__transformMatrix)}__getTransformScale(){return{x:Math.hypot(this.__transformMatrix.a,this.__transformMatrix.b),y:Math.hypot(this.__transformMatrix.c,this.__transformMatrix.d)}}__getTransformRotation(){return Math.atan2(this.__transformMatrix.b,this.__transformMatrix.a)}drawFocusRing(){}createImageData(){}putImageData(){}globalCompositeOperation(){}drawImage(){}createPattern(){return null}}});var bh={};dt(bh,{renderToSvg:()=>wh});function Y_(e){let t=e.visibleDomainTypes.map(o=>o.name),r=Math.max(0,...t.map(o=>o.length)),n=Ea*2+Ia+6+r*V_;return Math.min(360,Math.max(120,n))}function z_(e,t){let{width:r,height:n,scrollX:o,scrollY:i,totalWidth:a,totalHeight:s,treeAreaWidth:c,totalTrackAreaHeight:l,minimapHeight:A}=e,u=t.includeTracks?l:0,m=t.exportType==="viewport"&&!!t.includeMinimap,d=e.actuallyShowDomains&&e.visibleDomainTypes.length>0?Y_(e):0;return t.exportType==="entire"?{width:a+c,height:s+u,contentHeight:s,trackHeight:u,offsetX:0,offsetY:0,includeMinimap:m,legendWidth:d}:{width:r,height:n+(m?A:0)+u,contentHeight:n,trackHeight:u,offsetX:-o,offsetY:-i,includeMinimap:m,legendWidth:d}}async function wh(e,t){await(0,yh.when)(()=>e.dataInitialized);let{Context:r}=await Promise.resolve().then(()=>(Eh(),Ch));return(0,xh.renderToStaticMarkup)(X.default.createElement(W_,{model:e,theme:t.theme,Context:r,layout:z_(e,t)}))}function W_({model:e,theme:t,Context:r,layout:n}){let{width:o,height:i,trackHeight:a,includeMinimap:s,legendWidth:c}=n,{treeAreaWidth:l,minimapHeight:A}=e,u=o+c,m=s?A:0,d=X.default.createElement(X.default.Fragment,null,a>0?X.default.createElement(X_,{Context:r,model:e,theme:t,layout:n}):null,X.default.createElement("g",{transform:a>0?`translate(0 ${a})`:void 0},X.default.createElement(K_,{Context:r,model:e,theme:t,layout:n})));return X.default.createElement("svg",{width:u,height:i,xmlns:"http://www.w3.org/2000/svg",xmlnsXlink:"http://www.w3.org/1999/xlink",viewBox:`0 0 ${u} ${i}`},X.default.createElement("rect",{width:"100%",height:"100%",fill:"white"}),s?X.default.createElement(X.default.Fragment,null,X.default.createElement("g",{transform:`translate(${l} 0)`},X.default.createElement(Mg,{model:e})),X.default.createElement("g",{transform:`translate(0 ${A})`},d)):d,c>0?X.default.createElement("g",{transform:`translate(${o} ${m})`},X.default.createElement($_,{model:e,width:c})):null)}function $_({model:e,width:t}){let{visibleDomainTypes:r,fillPalette:n,strokePalette:o}=e,i=Ea*2+r.length*Ih;return X.default.createElement("g",null,X.default.createElement("rect",{x:0,y:0,width:t-4,height:i,fill:"white",stroke:"#ccc",rx:2}),r.map((a,s)=>{let c=Ea+s*Ih;return X.default.createElement("g",{key:a.accession},X.default.createElement("rect",{x:Ea,y:c,width:Ia,height:Ia,fill:n[a.accession],stroke:o[a.accession]}),X.default.createElement("text",{x:Ea+Ia+6,y:c+Ia-1,fontSize:J_},a.name))}))}function K_({model:e,theme:t,layout:r,Context:n}){let{contentHeight:o,offsetX:i,offsetY:a,width:s}=r,{treeAreaWidth:c,colorScheme:l,id:A}=e,u=s-c,m=Aa(l,t),d=new n(c,o);qs({model:e,theme:t,ctx:d,offsetY:a,blockSizeYOverride:o,highResScaleFactorOverride:1});let g=new n(u,o);return Fs({model:e,ctx:g,offsetX:i,offsetY:a,blockSizeYOverride:o,highResScaleFactorOverride:1}),Us({model:e,theme:t,ctx:g,contrastScheme:m,offsetX:i,offsetY:a,blockSizeXOverride:u,blockSizeYOverride:o,highResScaleFactorOverride:1}),X.default.createElement(X.default.Fragment,null,X.default.createElement(xu,{clipId:`tree-${A}`,width:c,height:o,ctx:d}),X.default.createElement(xu,{clipId:`msa-${A}`,width:u,height:o,transform:`translate(${c} 0)`,ctx:g}))}function X_({model:e,theme:t,layout:r,Context:n}){let{trackHeight:o,offsetX:i,width:a}=r,{treeAreaWidth:s,colorScheme:c,id:l}=e,A=a-s,u=Aa(c,t),m=new n(A,o);return oh({model:e,ctx:m,contrastScheme:u,offsetX:i,blockSizeXOverride:A,highResScaleFactorOverride:1}),X.default.createElement("g",{transform:`translate(${s} 0)`},X.default.createElement(xu,{clipId:`tracks-${l}`,width:A,height:o,ctx:m}))}function xu({clipId:e,width:t,height:r,transform:n,ctx:o}){return X.default.createElement(X.default.Fragment,null,X.default.createElement("defs",null,X.default.createElement("clipPath",{id:e},X.default.createElement("rect",{x:0,y:0,width:t,height:r}))),X.default.createElement("g",{clipPath:`url(#${e})`,transform:n,dangerouslySetInnerHTML:{__html:o.getSvg().innerHTML}}))}var X,xh,yh,Ea,Ih,Ia,J_,V_,yu=p(()=>{X=f(M(),1),xh=f(de(),1),yh=f(Vo(),1);_g();XA();Au();Hs();Js();xn();Ea=8,Ih=16,Ia=12,J_=12,V_=7});var Ne=V((zP,Bh)=>{Bh.exports=JBrowseExports["@jbrowse/core/ui"]});var Sh,Qh,$o,wu=p(()=>{Sh=f(R(),1),Qh=f(M(),1),$o=class extends Qh.Component{constructor(t){super(t),this.state={error:void 0}}componentDidCatch(t,r){console.error("ErrorBoundary caught an error:",t,r),this.setState({error:t})}render(){return this.state.error?(0,Sh.jsx)(this.props.FallbackComponent,{error:this.state.error}):this.props.children}}});var O=V(($P,vh)=>{vh.exports=JBrowseExports["@mui/material"]});function Z_(e){if(typeof window>"u")return()=>{};let t=window.matchMedia(`(resolution: ${window.devicePixelRatio}dppx)`);function r(){e(),t.removeEventListener("change",r),t=window.matchMedia(`(resolution: ${window.devicePixelRatio}dppx)`),t.addEventListener("change",r)}return t.addEventListener("change",r),()=>{t.removeEventListener("change",r)}}function eT(){return typeof window>"u"?1:window.devicePixelRatio}function _h(){return(0,Mh.useSyncExternalStore)(Z_,eT,()=>1)}var Mh,Th=p(()=>{Mh=f(M(),1)});function yn(e,t){let r=(0,Ko.useRef)(!1),[n,o]=(0,Ko.useState)();return(0,Ko.useEffect)(()=>{if(n!==void 0){let s=function(l){r.current||(r.current=!0,requestAnimationFrame(()=>{let A=e==="x"?l.clientX:l.clientY;t(A-i,a),r.current=!1}))},c=function(){o(void 0)},{client:i,startScroll:a}=n;return document.addEventListener("mousemove",s),document.addEventListener("mouseup",c),()=>{document.removeEventListener("mousemove",s),document.removeEventListener("mouseup",c)}}},[e,t,n]),{dragging:n!==void 0,startDrag:(i,a)=>{o({client:e==="x"?i.clientX:i.clientY,startScroll:a})}}}var Ko,Vs=p(()=>{Ko=f(M(),1)});var Xt,Ys,bu,Bu,kh,Dh,Nh,Su=p(()=>{Xt=f(M(),1),Ys=f(H(),1);Vs();bu="rgba(200,200,200)",Bu="rgba(150,150,150)",kh=(0,Ys.observer)(function({model:e}){let{resizeHandleWidth:t}=e,[r,n]=(0,Xt.useState)(!1),{startDrag:o}=yn("x",(0,Xt.useCallback)((i,a)=>{e.setTreeAreaWidth(a+i)},[e]));return Xt.default.createElement("div",{onMouseDown:i=>{o(i,e.treeAreaWidth)},onMouseEnter:()=>{n(!0)},onMouseLeave:()=>{n(!1)},style:{cursor:"ew-resize",width:t,background:r?Bu:bu,position:"relative"}})}),Dh=(0,Ys.observer)(function({model:e}){let{resizeHandleWidth:t}=e,[r,n]=(0,Xt.useState)(!1),{startDrag:o}=yn("y",(0,Xt.useCallback)((i,a)=>{e.setHeight(a+i)},[e]));return Xt.default.createElement("div",{onMouseDown:i=>{o(i,e.height)},onMouseEnter:()=>{n(!0)},onMouseLeave:()=>{n(!1)},style:{cursor:"ns-resize",width:"100%",height:t,background:r?Bu:bu,position:"relative"}})}),Nh=(0,Ys.observer)(function({model:e}){let{resizeHandleWidth:t}=e,[r,n]=(0,Xt.useState)(!1),{startDrag:o}=yn("y",(0,Xt.useCallback)((i,a)=>{e.setConservationTrackHeight(Math.max(10,a+i))},[e]));return Xt.default.createElement("div",{onMouseDown:i=>{o(i,e.conservationTrackHeight)},onMouseEnter:()=>{n(!0)},onMouseLeave:()=>{n(!1)},style:{position:"absolute",bottom:0,left:0,cursor:"ns-resize",width:"100%",height:t,zIndex:1,background:r?Bu:bu}})})});function rT(e){if(e.sheet)return e.sheet;for(var t=0;t<document.styleSheets.length;t++)if(document.styleSheets[t].ownerNode===e)return document.styleSheets[t]}function nT(e){var t=document.createElement("style");return t.setAttribute("data-emotion",e.key),e.nonce!==void 0&&t.setAttribute("nonce",e.nonce),t.appendChild(document.createTextNode("")),t.setAttribute("data-s",""),t}var tT,Lh,Rh=p(()=>{tT=!1;Lh=(function(){function e(r){var n=this;this._insertTag=function(o){var i;n.tags.length===0?n.insertionPoint?i=n.insertionPoint.nextSibling:n.prepend?i=n.container.firstChild:i=n.before:i=n.tags[n.tags.length-1].nextSibling,n.container.insertBefore(o,i),n.tags.push(o)},this.isSpeedy=r.speedy===void 0?!tT:r.speedy,this.tags=[],this.ctr=0,this.nonce=r.nonce,this.key=r.key,this.container=r.container,this.prepend=r.prepend,this.insertionPoint=r.insertionPoint,this.before=null}var t=e.prototype;return t.hydrate=function(n){n.forEach(this._insertTag)},t.insert=function(n){this.ctr%(this.isSpeedy?65e3:1)===0&&this._insertTag(nT(this));var o=this.tags[this.tags.length-1];if(this.isSpeedy){var i=rT(o);try{i.insertRule(n,i.cssRules.length)}catch{}}else o.appendChild(document.createTextNode(n));this.ctr++},t.flush=function(){this.tags.forEach(function(n){var o;return(o=n.parentNode)==null?void 0:o.removeChild(n)}),this.tags=[],this.ctr=0},e})()});var ot,xa,Z,zs,Xo,Zo,Fh,Ws,Ph,$s=p(()=>{ot="-ms-",xa="-moz-",Z="-webkit-",zs="comm",Xo="rule",Zo="decl",Fh="@import",Ws="@keyframes",Ph="@layer"});function Uh(e,t){return Le(e,0)^45?(((t<<2^Le(e,0))<<2^Le(e,1))<<2^Le(e,2))<<2^Le(e,3):0}function Ks(e){return e.trim()}function Qu(e,t){return(e=t.exec(e))?e[0]:e}function $(e,t,r){return e.replace(t,r)}function ya(e,t){return e.indexOf(t)}function Le(e,t){return e.charCodeAt(t)|0}function wn(e,t,r){return e.slice(t,r)}function bt(e){return e.length}function ei(e){return e.length}function ti(e,t){return t.push(e),e}function vu(e,t){return e.map(t).join("")}var Oh,oo,Gh,ri=p(()=>{Oh=Math.abs,oo=String.fromCharCode,Gh=Object.assign});function wa(e,t,r,n,o,i,a){return{value:e,root:t,parent:r,type:n,props:o,children:i,line:Xs,column:ni,length:a,return:""}}function ai(e,t){return Gh(wa("",null,null,"",null,null,0),e,{length:-e.length},t)}function jh(){return Ue}function qh(){return Ue=Bt>0?Le(ii,--Bt):0,ni--,Ue===10&&(ni=1,Xs--),Ue}function St(){return Ue=Bt<Hh?Le(ii,Bt++):0,ni++,Ue===10&&(ni=1,Xs++),Ue}function Zt(){return Le(ii,Bt)}function ba(){return Bt}function si(e,t){return wn(ii,e,t)}function oi(e){switch(e){case 0:case 9:case 10:case 13:case 32:return 5;case 33:case 43:case 44:case 47:case 62:case 64:case 126:case 59:case 123:case 125:return 4;case 58:return 3;case 34:case 39:case 40:case 91:return 2;case 41:case 93:return 1}return 0}function Zs(e){return Xs=ni=1,Hh=bt(ii=e),Bt=0,[]}function ec(e){return ii="",e}function ci(e){return Ks(si(Bt-1,Mu(e===91?e+2:e===40?e+1:e)))}function Jh(e){for(;(Ue=Zt())&&Ue<33;)St();return oi(e)>2||oi(Ue)>3?"":" "}function Vh(e,t){for(;--t&&St()&&!(Ue<48||Ue>102||Ue>57&&Ue<65||Ue>70&&Ue<97););return si(e,ba()+(t<6&&Zt()==32&&St()==32))}function Mu(e){for(;St();)switch(Ue){case e:return Bt;case 34:case 39:e!==34&&e!==39&&Mu(Ue);break;case 40:e===41&&Mu(e);break;case 92:St();break}return Bt}function Yh(e,t){for(;St()&&e+Ue!==57;)if(e+Ue===84&&Zt()===47)break;return"/*"+si(t,Bt-1)+"*"+oo(e===47?e:St())}function zh(e){for(;!oi(Zt());)St();return si(e,Bt)}var Xs,ni,Hh,Bt,Ue,ii,_u=p(()=>{ri();Xs=1,ni=1,Hh=0,Bt=0,Ue=0,ii=""});function Kh(e){return ec(tc("",null,null,null,[""],e=Zs(e),0,[0],e))}function tc(e,t,r,n,o,i,a,s,c){for(var l=0,A=0,u=a,m=0,d=0,g=0,C=1,y=1,I=1,E=0,b="",x=o,w=i,Q=n,S=b;y;)switch(g=E,E=St()){case 40:if(g!=108&&Le(S,u-1)==58){ya(S+=$(ci(E),"&","&\f"),"&\f")!=-1&&(I=-1);break}case 34:case 39:case 91:S+=ci(E);break;case 9:case 10:case 13:case 32:S+=Jh(g);break;case 92:S+=Vh(ba()-1,7);continue;case 47:switch(Zt()){case 42:case 47:ti(oT(Yh(St(),ba()),t,r),c);break;default:S+="/"}break;case 123*C:s[l++]=bt(S)*I;case 125*C:case 59:case 0:switch(E){case 0:case 125:y=0;case 59+A:I==-1&&(S=$(S,/\f/g,"")),d>0&&bt(S)-u&&ti(d>32?$h(S+";",n,r,u-1):$h($(S," ","")+";",n,r,u-2),c);break;case 59:S+=";";default:if(ti(Q=Wh(S,t,r,l,A,o,s,b,x=[],w=[],u),i),E===123)if(A===0)tc(S,t,Q,Q,x,i,u,s,w);else switch(m===99&&Le(S,3)===110?100:m){case 100:case 108:case 109:case 115:tc(e,Q,Q,n&&ti(Wh(e,Q,Q,0,0,o,s,b,o,x=[],u),w),o,w,u,s,n?x:w);break;default:tc(S,Q,Q,Q,[""],w,0,s,w)}}l=A=d=0,C=I=1,b=S="",u=a;break;case 58:u=1+bt(S),d=g;default:if(C<1){if(E==123)--C;else if(E==125&&C++==0&&qh()==125)continue}switch(S+=oo(E),E*C){case 38:I=A>0?1:(S+="\f",-1);break;case 44:s[l++]=(bt(S)-1)*I,I=1;break;case 64:Zt()===45&&(S+=ci(St())),m=Zt(),A=u=bt(b=S+=zh(ba())),E++;break;case 45:g===45&&bt(S)==2&&(C=0)}}return i}function Wh(e,t,r,n,o,i,a,s,c,l,A){for(var u=o-1,m=o===0?i:[""],d=ei(m),g=0,C=0,y=0;g<n;++g)for(var I=0,E=wn(e,u+1,u=Oh(C=a[g])),b=e;I<d;++I)(b=Ks(C>0?m[I]+" "+E:$(E,/&\f/g,m[I])))&&(c[y++]=b);return wa(e,t,r,o===0?Xo:s,c,l,A)}function oT(e,t,r){return wa(e,t,r,zs,oo(jh()),wn(e,2,-2),0)}function $h(e,t,r,n){return wa(e,t,r,Zo,wn(e,0,n),wn(e,n+1,-1),n)}var Xh=p(()=>{$s();ri();_u()});var Zh=p(()=>{});function io(e,t){for(var r="",n=ei(e),o=0;o<n;o++)r+=t(e[o],o,e,t)||"";return r}function e0(e,t,r,n){switch(e.type){case Ph:if(e.children.length)break;case Fh:case Zo:return e.return=e.return||e.value;case zs:return"";case Ws:return e.return=e.value+"{"+io(e.children,n)+"}";case Xo:e.value=e.props.join(",")}return bt(r=io(e.children,n))?e.return=e.value+"{"+r+"}":""}var t0=p(()=>{$s();ri()});function r0(e){var t=ei(e);return function(r,n,o,i){for(var a="",s=0;s<t;s++)a+=e[s](r,n,o,i)||"";return a}}function n0(e){return function(t){t.root||(t=t.return)&&e(t)}}var o0=p(()=>{ri()});var i0=p(()=>{$s();ri();Xh();Zh();_u();t0();o0()});var rc=p(()=>{});function a0(e){var t=Object.create(null);return function(r){return t[r]===void 0&&(t[r]=e(r)),t[r]}}var Tu=p(()=>{});function c0(e,t){switch(Uh(e,t)){case 5103:return Z+"print-"+e+e;case 5737:case 4201:case 3177:case 3433:case 1641:case 4457:case 2921:case 5572:case 6356:case 5844:case 3191:case 6645:case 3005:case 6391:case 5879:case 5623:case 6135:case 4599:case 4855:case 4215:case 6389:case 5109:case 5365:case 5621:case 3829:return Z+e+e;case 5349:case 4246:case 4810:case 6968:case 2756:return Z+e+xa+e+ot+e+e;case 6828:case 4268:return Z+e+ot+e+e;case 6165:return Z+e+ot+"flex-"+e+e;case 5187:return Z+e+$(e,/(\w+).+(:[^]+)/,Z+"box-$1$2"+ot+"flex-$1$2")+e;case 5443:return Z+e+ot+"flex-item-"+$(e,/flex-|-self/,"")+e;case 4675:return Z+e+ot+"flex-line-pack"+$(e,/align-content|flex-|-self/,"")+e;case 5548:return Z+e+ot+$(e,"shrink","negative")+e;case 5292:return Z+e+ot+$(e,"basis","preferred-size")+e;case 6060:return Z+"box-"+$(e,"-grow","")+Z+e+ot+$(e,"grow","positive")+e;case 4554:return Z+$(e,/([^-])(transform)/g,"$1"+Z+"$2")+e;case 6187:return $($($(e,/(zoom-|grab)/,Z+"$1"),/(image-set)/,Z+"$1"),e,"")+e;case 5495:case 3959:return $(e,/(image-set\([^]*)/,Z+"$1$`$1");case 4968:return $($(e,/(.+:)(flex-)?(.*)/,Z+"box-pack:$3"+ot+"flex-pack:$3"),/s.+-b[^;]+/,"justify")+Z+e+e;case 4095:case 3583:case 4068:case 2532:return $(e,/(.+)-inline(.+)/,Z+"$1$2")+e;case 8116:case 7059:case 5753:case 5535:case 5445:case 5701:case 4933:case 4677:case 5533:case 5789:case 5021:case 4765:if(bt(e)-1-t>6)switch(Le(e,t+1)){case 109:if(Le(e,t+4)!==45)break;case 102:return $(e,/(.+:)(.+)-([^]+)/,"$1"+Z+"$2-$3$1"+xa+(Le(e,t+3)==108?"$3":"$2-$3"))+e;case 115:return~ya(e,"stretch")?c0($(e,"stretch","fill-available"),t)+e:e}break;case 4949:if(Le(e,t+1)!==115)break;case 6444:switch(Le(e,bt(e)-3-(~ya(e,"!important")&&10))){case 107:return $(e,":",":"+Z)+e;case 101:return $(e,/(.+:)([^;!]+)(;|!.+)?/,"$1"+Z+(Le(e,14)===45?"inline-":"")+"box$3$1"+Z+"$2$3$1"+ot+"$2box$3")+e}break;case 5936:switch(Le(e,t+11)){case 114:return Z+e+ot+$(e,/[svh]\w+-[tblr]{2}/,"tb")+e;case 108:return Z+e+ot+$(e,/[svh]\w+-[tblr]{2}/,"tb-rl")+e;case 45:return Z+e+ot+$(e,/[svh]\w+-[tblr]{2}/,"lr")+e}return Z+e+ot+e+e}return e}var iT,aT,sT,s0,cT,lT,AT,uT,l0,ku=p(()=>{Rh();i0();rc();Tu();iT=function(t,r,n){for(var o=0,i=0;o=i,i=Zt(),o===38&&i===12&&(r[n]=1),!oi(i);)St();return si(t,Bt)},aT=function(t,r){var n=-1,o=44;do switch(oi(o)){case 0:o===38&&Zt()===12&&(r[n]=1),t[n]+=iT(Bt-1,r,n);break;case 2:t[n]+=ci(o);break;case 4:if(o===44){t[++n]=Zt()===58?"&\f":"",r[n]=t[n].length;break}default:t[n]+=oo(o)}while(o=St());return t},sT=function(t,r){return ec(aT(Zs(t),r))},s0=new WeakMap,cT=function(t){if(!(t.type!=="rule"||!t.parent||t.length<1)){for(var r=t.value,n=t.parent,o=t.column===n.column&&t.line===n.line;n.type!=="rule";)if(n=n.parent,!n)return;if(!(t.props.length===1&&r.charCodeAt(0)!==58&&!s0.get(n))&&!o){s0.set(t,!0);for(var i=[],a=sT(r,i),s=n.props,c=0,l=0;c<a.length;c++)for(var A=0;A<s.length;A++,l++)t.props[l]=i[c]?a[c].replace(/&\f/g,s[A]):s[A]+" "+a[c]}}},lT=function(t){if(t.type==="decl"){var r=t.value;r.charCodeAt(0)===108&&r.charCodeAt(2)===98&&(t.return="",t.value="")}};AT=function(t,r,n,o){if(t.length>-1&&!t.return)switch(t.type){case Zo:t.return=c0(t.value,t.length);break;case Ws:return io([ai(t,{value:$(t.value,"@","@"+Z)})],o);case Xo:if(t.length)return vu(t.props,function(i){switch(Qu(i,/(::plac\w+|:read-\w+)/)){case":read-only":case":read-write":return io([ai(t,{props:[$(i,/:(read-\w+)/,":"+xa+"$1")]})],o);case"::placeholder":return io([ai(t,{props:[$(i,/:(plac\w+)/,":"+Z+"input-$1")]}),ai(t,{props:[$(i,/:(plac\w+)/,":"+xa+"$1")]}),ai(t,{props:[$(i,/:(plac\w+)/,ot+"input-$1")]})],o)}return""})}},uT=[AT],l0=function(t){var r=t.key;if(r==="css"){var n=document.querySelectorAll("style[data-emotion]:not([data-s])");Array.prototype.forEach.call(n,function(C){var y=C.getAttribute("data-emotion");y.indexOf(" ")!==-1&&(document.head.appendChild(C),C.setAttribute("data-s",""))})}var o=t.stylisPlugins||uT,i={},a,s=[];a=t.container||document.head,Array.prototype.forEach.call(document.querySelectorAll('style[data-emotion^="'+r+' "]'),function(C){for(var y=C.getAttribute("data-emotion").split(" "),I=1;I<y.length;I++)i[y[I]]=!0;s.push(C)});var c,l=[cT,lT];{var A,u=[e0,n0(function(C){A.insert(C)})],m=r0(l.concat(o,u)),d=function(y){return io(Kh(y),m)};c=function(y,I,E,b){A=E,d(y?y+"{"+I.styles+"}":I.styles),b&&(g.inserted[I.name]=!0)}}var g={key:r,sheet:new Lh({key:r,container:a,nonce:t.nonce,speedy:t.speedy,prepend:t.prepend,insertionPoint:t.insertionPoint}),nonce:t.nonce,inserted:i,registered:{},insert:c};return g.sheet.hydrate(s),g}});var Du=p(()=>{});var u0=V(oe=>{"use strict";var $e=typeof Symbol=="function"&&Symbol.for,Nu=$e?Symbol.for("react.element"):60103,Lu=$e?Symbol.for("react.portal"):60106,nc=$e?Symbol.for("react.fragment"):60107,oc=$e?Symbol.for("react.strict_mode"):60108,ic=$e?Symbol.for("react.profiler"):60114,ac=$e?Symbol.for("react.provider"):60109,sc=$e?Symbol.for("react.context"):60110,Ru=$e?Symbol.for("react.async_mode"):60111,cc=$e?Symbol.for("react.concurrent_mode"):60111,lc=$e?Symbol.for("react.forward_ref"):60112,Ac=$e?Symbol.for("react.suspense"):60113,fT=$e?Symbol.for("react.suspense_list"):60120,uc=$e?Symbol.for("react.memo"):60115,fc=$e?Symbol.for("react.lazy"):60116,dT=$e?Symbol.for("react.block"):60121,mT=$e?Symbol.for("react.fundamental"):60117,pT=$e?Symbol.for("react.responder"):60118,gT=$e?Symbol.for("react.scope"):60119;function Ot(e){if(typeof e=="object"&&e!==null){var t=e.$$typeof;switch(t){case Nu:switch(e=e.type,e){case Ru:case cc:case nc:case ic:case oc:case Ac:return e;default:switch(e=e&&e.$$typeof,e){case sc:case lc:case fc:case uc:case ac:return e;default:return t}}case Lu:return t}}}function A0(e){return Ot(e)===cc}oe.AsyncMode=Ru;oe.ConcurrentMode=cc;oe.ContextConsumer=sc;oe.ContextProvider=ac;oe.Element=Nu;oe.ForwardRef=lc;oe.Fragment=nc;oe.Lazy=fc;oe.Memo=uc;oe.Portal=Lu;oe.Profiler=ic;oe.StrictMode=oc;oe.Suspense=Ac;oe.isAsyncMode=function(e){return A0(e)||Ot(e)===Ru};oe.isConcurrentMode=A0;oe.isContextConsumer=function(e){return Ot(e)===sc};oe.isContextProvider=function(e){return Ot(e)===ac};oe.isElement=function(e){return typeof e=="object"&&e!==null&&e.$$typeof===Nu};oe.isForwardRef=function(e){return Ot(e)===lc};oe.isFragment=function(e){return Ot(e)===nc};oe.isLazy=function(e){return Ot(e)===fc};oe.isMemo=function(e){return Ot(e)===uc};oe.isPortal=function(e){return Ot(e)===Lu};oe.isProfiler=function(e){return Ot(e)===ic};oe.isStrictMode=function(e){return Ot(e)===oc};oe.isSuspense=function(e){return Ot(e)===Ac};oe.isValidElementType=function(e){return typeof e=="string"||typeof e=="function"||e===nc||e===cc||e===ic||e===oc||e===Ac||e===fT||typeof e=="object"&&e!==null&&(e.$$typeof===fc||e.$$typeof===uc||e.$$typeof===ac||e.$$typeof===sc||e.$$typeof===lc||e.$$typeof===mT||e.$$typeof===pT||e.$$typeof===gT||e.$$typeof===dT)};oe.typeOf=Ot});var d0=V((D4,f0)=>{"use strict";f0.exports=u0()});var I0=V((N4,E0)=>{"use strict";var Fu=d0(),hT={childContextTypes:!0,contextType:!0,contextTypes:!0,defaultProps:!0,displayName:!0,getDefaultProps:!0,getDerivedStateFromError:!0,getDerivedStateFromProps:!0,mixins:!0,propTypes:!0,type:!0},CT={name:!0,length:!0,prototype:!0,caller:!0,callee:!0,arguments:!0,arity:!0},ET={$$typeof:!0,render:!0,defaultProps:!0,displayName:!0,propTypes:!0},h0={$$typeof:!0,compare:!0,defaultProps:!0,displayName:!0,propTypes:!0,type:!0},Pu={};Pu[Fu.ForwardRef]=ET;Pu[Fu.Memo]=h0;function m0(e){return Fu.isMemo(e)?h0:Pu[e.$$typeof]||hT}var IT=Object.defineProperty,xT=Object.getOwnPropertyNames,p0=Object.getOwnPropertySymbols,yT=Object.getOwnPropertyDescriptor,wT=Object.getPrototypeOf,g0=Object.prototype;function C0(e,t,r){if(typeof t!="string"){if(g0){var n=wT(t);n&&n!==g0&&C0(e,n,r)}var o=xT(t);p0&&(o=o.concat(p0(t)));for(var i=m0(e),a=m0(t),s=0;s<o.length;++s){var c=o[s];if(!CT[c]&&!(r&&r[c])&&!(a&&a[c])&&!(i&&i[c])){var l=yT(t,c);try{IT(e,c,l)}catch{}}}}return e}E0.exports=C0});function Ba(e,t,r){var n="";return r.split(" ").forEach(function(o){e[o]!==void 0?t.push(e[o]+";"):o&&(n+=o+" ")}),n}var bT,dc,Sa,mc=p(()=>{bT=!0;dc=function(t,r,n){var o=t.key+"-"+r.name;(n===!1||bT===!1)&&t.registered[o]===void 0&&(t.registered[o]=r.styles)},Sa=function(t,r,n){dc(t,r,n);var o=t.key+"-"+r.name;if(t.inserted[r.name]===void 0){var i=r;do t.insert(r===i?"."+o:"",i,t.sheet,!0),i=i.next;while(i!==void 0)}}});function x0(e){for(var t=0,r,n=0,o=e.length;o>=4;++n,o-=4)r=e.charCodeAt(n)&255|(e.charCodeAt(++n)&255)<<8|(e.charCodeAt(++n)&255)<<16|(e.charCodeAt(++n)&255)<<24,r=(r&65535)*1540483477+((r>>>16)*59797<<16),r^=r>>>24,t=(r&65535)*1540483477+((r>>>16)*59797<<16)^(t&65535)*1540483477+((t>>>16)*59797<<16);switch(o){case 3:t^=(e.charCodeAt(n+2)&255)<<16;case 2:t^=(e.charCodeAt(n+1)&255)<<8;case 1:t^=e.charCodeAt(n)&255,t=(t&65535)*1540483477+((t>>>16)*59797<<16)}return t^=t>>>13,t=(t&65535)*1540483477+((t>>>16)*59797<<16),((t^t>>>15)>>>0).toString(36)}var y0=p(()=>{});var w0,b0=p(()=>{w0={animationIterationCount:1,aspectRatio:1,borderImageOutset:1,borderImageSlice:1,borderImageWidth:1,boxFlex:1,boxFlexGroup:1,boxOrdinalGroup:1,columnCount:1,columns:1,flex:1,flexGrow:1,flexPositive:1,flexShrink:1,flexNegative:1,flexOrder:1,gridRow:1,gridRowEnd:1,gridRowSpan:1,gridRowStart:1,gridColumn:1,gridColumnEnd:1,gridColumnSpan:1,gridColumnStart:1,msGridRow:1,msGridRowSpan:1,msGridColumn:1,msGridColumnSpan:1,fontWeight:1,lineHeight:1,opacity:1,order:1,orphans:1,scale:1,tabSize:1,widows:1,zIndex:1,zoom:1,WebkitLineClamp:1,fillOpacity:1,floodOpacity:1,stopOpacity:1,strokeDasharray:1,strokeDashoffset:1,strokeMiterlimit:1,strokeOpacity:1,strokeWidth:1}});function Qa(e,t,r){if(r==null)return"";var n=r;if(n.__emotion_styles!==void 0)return n;switch(typeof r){case"boolean":return"";case"object":{var o=r;if(o.anim===1)return Dr={name:o.name,styles:o.styles,next:Dr},o.name;var i=r;if(i.styles!==void 0){var a=i.next;if(a!==void 0)for(;a!==void 0;)Dr={name:a.name,styles:a.styles,next:Dr},a=a.next;var s=i.styles+";";return s}return MT(e,t,r)}case"function":{if(e!==void 0){var c=Dr,l=r(e);return Dr=c,Qa(e,t,l)}break}}var A=r;if(t==null)return A;var u=t[A];return u!==void 0?u:A}function MT(e,t,r){var n="";if(Array.isArray(r))for(var o=0;o<r.length;o++)n+=Qa(e,t,r[o])+";";else for(var i in r){var a=r[i];if(typeof a!="object"){var s=a;t!=null&&t[s]!==void 0?n+=i+"{"+t[s]+"}":B0(s)&&(n+=Ou(i)+":"+S0(i,s)+";")}else{if(i==="NO_COMPONENT_SELECTOR"&&BT)throw new Error(vT);if(Array.isArray(a)&&typeof a[0]=="string"&&(t==null||t[a[0]]===void 0))for(var c=0;c<a.length;c++)B0(a[c])&&(n+=Ou(i)+":"+S0(i,a[c])+";");else{var l=Qa(e,t,a);switch(i){case"animation":case"animationName":{n+=Ou(i)+":"+l+";";break}default:n+=i+"{"+l+"}"}}}}return n}function li(e,t,r){if(e.length===1&&typeof e[0]=="object"&&e[0]!==null&&e[0].styles!==void 0)return e[0];var n=!0,o="";Dr=void 0;var i=e[0];if(i==null||i.raw===void 0)n=!1,o+=Qa(r,t,i);else{var a=i;o+=a[0]}for(var s=1;s<e.length;s++)if(o+=Qa(r,t,e[s]),n){var c=i;o+=c[s]}Q0.lastIndex=0;for(var l="",A;(A=Q0.exec(o))!==null;)l+="-"+A[1];var u=x0(o)+l;return{name:u,styles:o,next:Dr}}var BT,ST,QT,v0,B0,Ou,S0,vT,Q0,Dr,pc=p(()=>{y0();b0();Tu();BT=!1,ST=/[A-Z]|^ms/g,QT=/_EMO_([^_]+?)_([^]*?)_EMO_/g,v0=function(t){return t.charCodeAt(1)===45},B0=function(t){return t!=null&&typeof t!="boolean"},Ou=a0(function(e){return v0(e)?e:e.replace(ST,"-$&").toLowerCase()}),S0=function(t,r){switch(t){case"animation":case"animationName":if(typeof r=="string")return r.replace(QT,function(n,o,i){return Dr={name:o,styles:i,next:Dr},o})}return w0[t]!==1&&!v0(t)&&typeof r=="number"&&r!==0?r+"px":r},vT="Component selectors can only be used in conjunction with @emotion/babel-plugin, the swc Emotion plugin, or another Emotion-aware compiler transform.";Q0=/label:\s*([^\s;{]+)\s*(;|$)/g});var gc,_T,TT,Gu,Uu=p(()=>{gc=f(M()),_T=function(t){return t()},TT=gc.useInsertionEffect?gc.useInsertionEffect:!1,Gu=TT||_T});var er,va,M0,ju,kT,qu,Ju,Vu,hc,Hu,_0,DT,NT,T0,Yu=p(()=>{er=f(M()),va=f(M());ku();Du();rc();mc();pc();Uu();M0=!1,ju=er.createContext(typeof HTMLElement<"u"?l0({key:"css"}):null),kT=ju.Provider,qu=function(){return(0,va.useContext)(ju)},Ju=function(t){return(0,va.forwardRef)(function(r,n){var o=(0,va.useContext)(ju);return t(r,o,n)})},Vu=er.createContext({}),hc={}.hasOwnProperty,Hu="__EMOTION_TYPE_PLEASE_DO_NOT_USE__",_0=function(t,r){var n={};for(var o in r)hc.call(r,o)&&(n[o]=r[o]);return n[Hu]=t,n},DT=function(t){var r=t.cache,n=t.serialized,o=t.isStringTag;return dc(r,n,o),Gu(function(){return Sa(r,n,o)}),null},NT=Ju(function(e,t,r){var n=e.css;typeof n=="string"&&t.registered[n]!==void 0&&(n=t.registered[n]);var o=e[Hu],i=[n],a="";typeof e.className=="string"?a=Ba(t.registered,i,e.className):e.className!=null&&(a=e.className+" ");var s=li(i,void 0,er.useContext(Vu));a+=t.key+"-"+s.name;var c={};for(var l in e)hc.call(e,l)&&l!=="css"&&l!==Hu&&!M0&&(c[l]=e[l]);return c.className=a,r&&(c.ref=r),er.createElement(er.Fragment,null,er.createElement(DT,{cache:t,serialized:s,isStringTag:typeof o=="string"}),er.createElement(o,c))}),T0=NT});function LT(){for(var e=arguments.length,t=new Array(e),r=0;r<e;r++)t[r]=arguments[r];return li(t)}function zu(){var e=LT.apply(void 0,arguments),t="animation-"+e.name;return{name:t,styles:"@keyframes "+t+"{"+e.styles+"}",anim:1,toString:function(){return"_EMO_"+this.name+"_"+this.styles+"_EMO_"}}}var Ai,l8,k0,Wu=p(()=>{Yu();Yu();Ai=f(M());mc();Uu();pc();ku();Du();rc();l8=f(I0()),k0=function(t,r){var n=arguments;if(r==null||!hc.call(r,"css"))return Ai.createElement.apply(void 0,n);var o=n.length,i=new Array(o);i[0]=T0,i[1]=_0(t,r);for(var a=2;a<o;a++)i[a]=n[a];return Ai.createElement.apply(null,i)};(function(e){var t;t||(t=e.JSX||(e.JSX={}))})(k0||(k0={}))});var $u=V((f8,D0)=>{D0.exports=JBrowseExports["@mui/material/styles"]});var ui,Ku=p(()=>{ui=e=>{let t=e.length,r=0,n="";for(;r<t;r++){let o=e[r];if(o==null)continue;let i;switch(typeof o){case"boolean":break;case"object":{if(Array.isArray(o))i=ui(o);else{let a=o;i="";for(let s in a)a[s]&&s&&(i&&(i+=" "),i+=s)}break}default:i=o}i&&(n&&(n+=" "),n+=i)}return n}});function N0(e){return e instanceof Object&&!("styles"in e)&&!("length"in e)&&!("__emotion_styles"in e)}var L0=p(()=>{});function P0(e){let{useCache:t}=e;function r(){let n=t(),{css:o,cx:i}=(0,F0.useMemo)(()=>RT({cache:n}),[n]);return{css:o,cx:i}}return{useCssAndCx:r}}var F0,RT,R0,O0=p(()=>{F0=f(M(),1);pc();mc();Ku();L0();({createCssAndCx:RT}=(()=>{function e(r,n,o){let i=[],a=Ba(r,i,o);return i.length<2?o:a+n(i)}function t(r){let{cache:n}=r,o=(...a)=>{let s=li(a,n.registered);Sa(n,s,!1);let c=`${n.key}-${s.name}`;e:{let l=a[0];if(!N0(l))break e;R0.saveClassNameCSSObjectMapping(n,c,l)}return c};return{css:o,cx:(...a)=>{let s=ui(a),c=R0.fixClassName(n,s,o);return e(n.registered,o,c)}}}return{createCssAndCx:t}})());R0=(()=>{let e=new WeakMap;return{saveClassNameCSSObjectMapping:(t,r,n)=>{let o=e.get(t);o===void 0&&(o=new Map,e.set(t,o)),o.set(r,n)},fixClassName:(()=>{function t(r){let n=!1;return r.map(([o,i])=>{if(i===void 0)return o;let a;if(n)a={"&&":i};else{a=o;for(let s in i)if(s.startsWith("@media")){n=!0;break}}return a})}return(r,n,o)=>{if(!n.includes(" "))return n;let i=e.get(r);return ui(t(n.split(" ").map(a=>[a,i?.get(a)])).map(a=>typeof a=="string"?a:o(a)))}})()}})()});function G0(e,t,r){if(!(t instanceof Object))return e;let n=Object.keys(t);if(n.length===0)return e;let o={};for(let i of Object.keys(e))o[i]=r(e[i],t[i]);for(let i of n){if(i in e)continue;let a=t[i];typeof a=="string"&&(o[i]=a)}return o}var U0=p(()=>{});function H0(e){if(!(e instanceof Object)||typeof e=="function")return e;let t=[];for(let r in e){let n=e[r],o=typeof n;if(!(o==="string"||o==="number"&&!isNaN(n)||o==="boolean"||n===void 0||n===null))return e;t.push(`${r}:${o}_${n}`)}return`xSqLiJdLMd9s${t.join("|")}`}var j0=p(()=>{});function q0(e){let{useTheme:t}=e,{useCssAndCx:r}=P0({useCache:FT});function n(){return function(o){let i=typeof o=="function"?o:()=>o;return function(s,c){let l=t(),{css:A,cx:u}=r(),m=(0,Xu.useMemo)(()=>{let y=i(l),I={};for(let E of Object.keys(y)){let b=y[E];I[E]=A(b)}return I},[A,l]),d=c?.props.classes,g=H0(d);return{classes:(0,Xu.useMemo)(()=>d?G0(m,d,u):m,[m,g,u]),theme:l,css:A,cx:u}}}}return{makeStyles:n}}var Xu,FT,J0=p(()=>{"use client";Xu=f(M(),1);Wu();O0();U0();j0();FT=qu});var V0,Y,Y0=p(()=>{V0=f($u(),1);J0();({makeStyles:Y}=q0({useTheme:V0.useTheme}))});var z0=p(()=>{Y0()});function Cc(...e){return ui(e)}var Re=p(()=>{"use client";Wu();z0();Ku()});var W0,$0,K0=p(()=>{"use client";me();W0=f(R(),1),$0=(0,j.createSvgIcon)((0,W0.jsx)("path",{d:"m7 10 5 5 5-5z"}),"ArrowDropDown")});function X0(e,t){return t===1?e*16:t===2?e*100:e}function Z0(e){let t=Math.abs(e);return t<6?25:t>150?500:t>30?150:75}function eC(e,t){let r=PT*t,n=Math.max(-r,Math.min(r,e));return n>0?1/(1+n):1-n}var PT,tC=p(()=>{PT=.011997600479904018});function fi({ref:e,onScrollX:t,onScrollY:r,onZoom:n,scrollZoom:o}){let i=(0,mt.useRef)(!1),a=(0,mt.useRef)(!1),s=(0,mt.useRef)(0),c=(0,mt.useRef)(0),l=(0,mt.useRef)(0),A=(0,mt.useRef)(0),u=(0,mt.useRef)(0),m=(0,mt.useRef)(null),d=(0,mt.useRef)(0),g=(0,mt.useRef)(0),[C,y]=(0,mt.useState)(!1);(0,mt.useEffect)(()=>{let b=e.current;if(!b)return;function x(w){let Q=w.ctrlKey||w.metaKey,S=o&&!w.shiftKey&&Math.abs(w.deltaY)>=Math.abs(w.deltaX);if(n&&(Q||S)){let _=b.getBoundingClientRect(),v=X0(w.deltaY,w.deltaMode),L=Q?Z0(v):500;l.current+=v/L,A.current=w.clientX-_.left,u.current=w.clientY-_.top,a.current||(a.current=!0,requestAnimationFrame(U=>{let W=m.current===null?16.67:U-m.current;m.current=U,n(eC(l.current,Math.min(100,W)),A.current,u.current),l.current=0,a.current=!1})),w.preventDefault(),w.stopPropagation();return}let k=!!t&&w.deltaX!==0,N=!!r&&w.deltaY!==0;(k||N)&&(t&&(s.current+=w.deltaX),r&&(c.current+=w.deltaY),i.current||(i.current=!0,requestAnimationFrame(()=>{t&&(t(-s.current),s.current=0),r&&(r(-c.current),c.current=0),i.current=!1})),w.preventDefault(),w.stopPropagation())}return b.addEventListener("wheel",x,{passive:!1}),()=>{b.removeEventListener("wheel",x)}},[e,t,r,n,o]),(0,mt.useEffect)(()=>{if(!C)return;function b(w){w.preventDefault();let Q=w.clientX-d.current,S=w.clientY-g.current;(Q&&t||S&&r)&&(i.current||(i.current=!0,requestAnimationFrame(()=>{t?.(Q),r?.(S),i.current=!1,d.current=w.clientX,g.current=w.clientY})))}function x(){d.current=0,g.current=0,y(!1)}return window.addEventListener("mousemove",b,!0),window.addEventListener("mouseup",x,!0),()=>{window.removeEventListener("mousemove",b,!0),window.removeEventListener("mouseup",x,!0)}},[C,t,r]);function I(b){let x=b.target;x.draggable||x.dataset.resizer||b.button===0&&(d.current=b.clientX,g.current=b.clientY,y(!0))}function E(b){b.preventDefault(),y(!1)}return{onMouseDown:I,onMouseUp:E}}var mt,Ec=p(()=>{mt=f(M(),1);tC()});function Ma(e){let t=navigator.clipboard;if(t?.writeText){t.writeText(e).catch(n=>{console.error("Failed to copy to clipboard:",n)});return}let r=document.createElement("textarea");r.value=e,r.style.position="fixed",r.style.opacity="0",document.body.append(r),r.select(),document.execCommand("copy"),r.remove()}var Zu=p(()=>{});var oC={};dt(oC,{default:()=>HT});var en,rC,ao,nC,GT,UT,HT,iC=p(()=>{en=f(M(),1),rC=f(Ne(),1);Re();ao=f(O(),1),nC=f(H(),1);Zu();GT=Y()(e=>({textArea:{padding:e.spacing(2),overflow:"auto",background:"#ddd",wordBreak:"break-word"}})),UT=(0,nC.observer)(function({model:e,onClose:t}){let[r,n]=(0,en.useState)("Copy to clipboard"),{classes:o}=GT();return en.default.createElement(rC.Dialog,{open:!0,onClose:t,fullWidth:!0,maxWidth:"lg",title:`Track info - ${e.name}`},en.default.createElement(ao.DialogContent,null,en.default.createElement(ao.Button,{variant:"contained",color:"primary",onClick:()=>{Ma(e.data),n("Copied!"),setTimeout(()=>{n("Copy to clipboard")},300)}},r),en.default.createElement("pre",{className:o.textArea},e.data)),en.default.createElement(ao.DialogActions,null,en.default.createElement(ao.Button,{variant:"contained",onClick:t,color:"secondary"},"Close")))}),HT=UT});var He,so,ef,jT,qT,JT,VT,aC,sC=p(()=>{He=f(M(),1);Re();K0();so=f(O(),1),ef=f(H(),1);Ec();jT=(0,He.lazy)(()=>Promise.resolve().then(()=>(iC(),oC))),qT=Y()({button:{padding:0}}),JT=(0,ef.observer)(function({model:t,track:r}){let[n,o]=(0,He.useState)(),i=()=>{o(void 0)},{drawLabels:a,fontSize:s,treeAreaWidth:c}=t,{model:{name:l,height:A}}=r,{classes:u}=qT(),m=Math.min(A,s);return He.default.createElement("div",{style:{width:c,height:A,flexShrink:0,textAlign:"right",fontSize:m}},a?l:""," ",He.default.createElement(so.IconButton,{className:u.button,style:{width:m,height:m},onClick:d=>{o(d.currentTarget)}},He.default.createElement($0,null)),n?He.default.createElement(so.Menu,{anchorEl:n,transitionDuration:0,open:!0,onClose:()=>{i()}},He.default.createElement(so.MenuItem,{dense:!0,onClick:()=>{t.toggleTrack(r.model.id),i()}},"Close"),He.default.createElement(so.MenuItem,{dense:!0,onClick:()=>{t.queueDialog(d=>[jT,{onClose:d,model:r.model}]),i()}},"Get info")):null)}),VT=(0,ef.observer)(function({model:e,track:t}){let{resizeHandleWidth:r,colWidth:n,scrollX:o,numColumns:i}=e,{model:{height:a}}=t,s=(0,He.useRef)(null),c=(0,He.useCallback)(l=>{e.doScrollX(l)},[e]);return fi({ref:s,onScrollX:c}),He.default.createElement("div",{style:{display:"flex",height:a}},He.default.createElement(JT,{model:e,track:t}),He.default.createElement("div",{style:{width:r,flexShrink:0}}),He.default.createElement("div",{ref:s,onMouseMove:l=>{if(!s.current)return;let{left:A}=s.current.getBoundingClientRect(),u=l.clientX-A-o,m=Math.floor(u/n);m>=0&&m<i?e.setMousePos(m,void 0):e.setMousePos(void 0,void 0)},onMouseLeave:()=>{e.setMousePos(void 0,void 0)}},He.default.createElement(t.ReactComponent,{model:e,track:t})))}),aC=VT});var co,cC,lC,YT,AC,uC=p(()=>{co=f(M(),1),cC=f(de(),1),lC=f(H(),1);Vs();YT=(0,lC.observer)(({model:e})=>{let{msaAreaHeight:t,scrollY:r,totalHeight:n}=e,[o,i]=(0,co.useState)(!1),a="rgba(66, 119, 127, 0.3)",s=t/n,c=-r,l=c+t,A=c*s,u=l*s,{startDrag:m}=yn("y",(0,co.useCallback)((d,g)=>{e.setScrollY((0,cC.clamp)(g-d/s,e.maxScrollY,0))},[e,s]));return co.default.createElement("div",{style:{position:"relative",width:20,height:t,borderLeft:"1px solid #555",borderTop:"1px solid #555",boxSizing:"border-box"}},co.default.createElement("div",{style:{position:"absolute",top:Math.max(0,A),left:0,background:o?"rgba(66,119,127,0.6)":a,cursor:"pointer",boxSizing:"border-box",width:20,height:Math.max(u-A,20),zIndex:100},onMouseOver:()=>{i(!0)},onMouseOut:()=>{i(!1)},onMouseDown:d=>{m(d,e.scrollY)}}))}),AC=YT});function tf(){let e=(0,di.useRef)(null),[t,r]=(0,di.useState)({width:void 0,height:void 0});return(0,di.useEffect)(()=>{if(!e.current)return;let n=typeof window<"u"&&"ResizeObserver"in window?window.ResizeObserver:void 0;if(!n)return;let o=new n(i=>{r({width:i[0].contentRect.width,height:i[0].contentRect.height})});return o.observe(e.current),()=>{o.disconnect()}},[]),[e,t]}var di,fC=p(()=>{di=f(M(),1)});var dC,mC,pC=p(()=>{"use client";me();dC=f(R(),1),mC=(0,j.createSvgIcon)((0,dC.jsx)("path",{d:"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m1 17h-2v-2h2zm2.07-7.75-.9.92C13.45 12.9 13 13.5 13 15h-2v-.5c0-1.1.45-2.1 1.17-2.83l1.24-1.26c.37-.36.59-.86.59-1.41 0-1.1-.9-2-2-2s-2 .9-2 2H8c0-2.21 1.79-4 4-4s4 1.79 4 4c0 .88-.36 1.68-.93 2.25"}),"Help")});var hC=V((X8,gC)=>{gC.exports=JBrowseExports["@mui/material/utils"]});var Ee,Gt=p(()=>{"use client";Ee=f(hC(),1)});var CC,EC,IC=p(()=>{"use client";Gt();CC=f(R(),1),EC=(0,Ee.createSvgIcon)((0,CC.jsx)("path",{d:"M10 6 8.59 7.41 13.17 12l-4.58 4.59L10 18l6-6z"}),"ChevronRight")});var xC,yC,wC=p(()=>{"use client";Gt();xC=f(R(),1),yC=(0,Ee.createSvgIcon)((0,xC.jsx)("path",{d:"M11 18h2v-2h-2zm1-16C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m0 18c-4.41 0-8-3.59-8-8s3.59-8 8-8 8 3.59 8 8-3.59 8-8 8m0-14c-2.21 0-4 1.79-4 4h2c0-1.1.9-2 2-2s2 .9 2 2c0 2-3 1.75-3 5h2c0-2.25 3-2.5 3-5 0-2.21-1.79-4-4-4"}),"HelpOutline")});var bC,Ic,rf=p(()=>{"use client";Gt();bC=f(R(),1),Ic=(0,Ee.createSvgIcon)((0,bC.jsx)("path",{d:"M19 6.41 17.59 5 12 10.59 6.41 5 5 6.41 10.59 12 5 17.59 6.41 19 12 13.41 17.59 19 19 17.59 13.41 12z"}),"Close")});var BC,SC,QC=p(()=>{"use client";Gt();BC=f(R(),1),SC=(0,Ee.createSvgIcon)((0,BC.jsx)("path",{d:"M17.65 6.35C16.2 4.9 14.21 4 12 4c-4.42 0-7.99 3.58-7.99 8s3.57 8 7.99 8c3.73 0 6.84-2.55 7.73-6h-2.08c-.82 2.33-3.04 4-5.65 4-3.31 0-6-2.69-6-6s2.69-6 6-6c1.66 0 3.14.69 4.22 1.78L13 11h7V4z"}),"Refresh")});var vC,MC,_C=p(()=>{"use client";Gt();vC=f(R(),1),MC=(0,Ee.createSvgIcon)((0,vC.jsx)("path",{d:"M15.73 3H8.27L3 8.27v7.46L8.27 21h7.46L21 15.73V8.27zM12 17.3c-.72 0-1.3-.58-1.3-1.3s.58-1.3 1.3-1.3 1.3.58 1.3 1.3-.58 1.3-1.3 1.3m1-4.3h-2V7h2z"}),"Report")});function nf({children:e}){let{classes:t}=zT();return(0,TC.jsx)("div",{className:t.bg,children:e})}var TC,zT,kC=p(()=>{TC=f(R(),1);Re();zT=Y()(e=>({bg:{padding:4,margin:4,overflow:"auto",maxHeight:200,background:e.palette.mode==="dark"?"#833":"#f88",border:`1px solid ${e.palette.divider}`}}))});var NC=V(of=>{var DC="ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/".split("");of.encode=function(e){if(0<=e&&e<DC.length)return DC[e];throw new TypeError("Must be between 0 and 63: "+e)};of.decode=function(e){var t=65,r=90,n=97,o=122,i=48,a=57,s=43,c=47,l=26,A=52;return t<=e&&e<=r?e-t:n<=e&&e<=o?e-n+l:i<=e&&e<=a?e-i+A:e==s?62:e==c?63:-1}});var cf=V(sf=>{var LC=NC(),af=5,RC=1<<af,FC=RC-1,PC=RC;function WT(e){return e<0?(-e<<1)+1:(e<<1)+0}function $T(e){var t=(e&1)===1,r=e>>1;return t?-r:r}sf.encode=function(t){var r="",n,o=WT(t);do n=o&FC,o>>>=af,o>0&&(n|=PC),r+=LC.encode(n);while(o>0);return r};sf.decode=function(t,r,n){var o=t.length,i=0,a=0,s,c;do{if(r>=o)throw new Error("Expected more digits in base 64 VLQ value.");if(c=LC.decode(t.charCodeAt(r++)),c===-1)throw new Error("Invalid base64 digit: "+t.charAt(r-1));s=!!(c&PC),c&=FC,i=i+(c<<a),a+=af}while(s);n.value=$T(i),n.rest=r}});var pi=V(Ke=>{function KT(e,t,r){if(t in e)return e[t];if(arguments.length===3)return r;throw new Error('"'+t+'" is a required argument.')}Ke.getArg=KT;var OC=/^(?:([\w+\-.]+):)?\/\/(?:(\w+:\w+)@)?([\w.-]*)(?::(\d+))?(.*)$/,XT=/^data:.+\,.+$/;function _a(e){var t=e.match(OC);return t?{scheme:t[1],auth:t[2],host:t[3],port:t[4],path:t[5]}:null}Ke.urlParse=_a;function mi(e){var t="";return e.scheme&&(t+=e.scheme+":"),t+="//",e.auth&&(t+=e.auth+"@"),e.host&&(t+=e.host),e.port&&(t+=":"+e.port),e.path&&(t+=e.path),t}Ke.urlGenerate=mi;var ZT=32;function ek(e){var t=[];return function(r){for(var n=0;n<t.length;n++)if(t[n].input===r){var o=t[0];return t[0]=t[n],t[n]=o,t[0].result}var i=e(r);return t.unshift({input:r,result:i}),t.length>ZT&&t.pop(),i}}var lf=ek(function(t){var r=t,n=_a(t);if(n){if(!n.path)return t;r=n.path}for(var o=Ke.isAbsolute(r),i=[],a=0,s=0;;)if(a=s,s=r.indexOf("/",a),s===-1){i.push(r.slice(a));break}else for(i.push(r.slice(a,s));s<r.length&&r[s]==="/";)s++;for(var c,l=0,s=i.length-1;s>=0;s--)c=i[s],c==="."?i.splice(s,1):c===".."?l++:l>0&&(c===""?(i.splice(s+1,l),l=0):(i.splice(s,2),l--));return r=i.join("/"),r===""&&(r=o?"/":"."),n?(n.path=r,mi(n)):r});Ke.normalize=lf;function GC(e,t){e===""&&(e="."),t===""&&(t=".");var r=_a(t),n=_a(e);if(n&&(e=n.path||"/"),r&&!r.scheme)return n&&(r.scheme=n.scheme),mi(r);if(r||t.match(XT))return t;if(n&&!n.host&&!n.path)return n.host=t,mi(n);var o=t.charAt(0)==="/"?t:lf(e.replace(/\/+$/,"")+"/"+t);return n?(n.path=o,mi(n)):o}Ke.join=GC;Ke.isAbsolute=function(e){return e.charAt(0)==="/"||OC.test(e)};function tk(e,t){e===""&&(e="."),e=e.replace(/\/$/,"");for(var r=0;t.indexOf(e+"/")!==0;){var n=e.lastIndexOf("/");if(n<0||(e=e.slice(0,n),e.match(/^([^\/]+:\/)?\/*$/)))return t;++r}return Array(r+1).join("../")+t.substr(e.length+1)}Ke.relative=tk;var UC=(function(){var e=Object.create(null);return!("__proto__"in e)})();function HC(e){return e}function rk(e){return jC(e)?"$"+e:e}Ke.toSetString=UC?HC:rk;function nk(e){return jC(e)?e.slice(1):e}Ke.fromSetString=UC?HC:nk;function jC(e){if(!e)return!1;var t=e.length;if(t<9||e.charCodeAt(t-1)!==95||e.charCodeAt(t-2)!==95||e.charCodeAt(t-3)!==111||e.charCodeAt(t-4)!==116||e.charCodeAt(t-5)!==111||e.charCodeAt(t-6)!==114||e.charCodeAt(t-7)!==112||e.charCodeAt(t-8)!==95||e.charCodeAt(t-9)!==95)return!1;for(var r=t-10;r>=0;r--)if(e.charCodeAt(r)!==36)return!1;return!0}function ok(e,t,r){var n=tn(e.source,t.source);return n!==0||(n=e.originalLine-t.originalLine,n!==0)||(n=e.originalColumn-t.originalColumn,n!==0||r)||(n=e.generatedColumn-t.generatedColumn,n!==0)||(n=e.generatedLine-t.generatedLine,n!==0)?n:tn(e.name,t.name)}Ke.compareByOriginalPositions=ok;function ik(e,t,r){var n;return n=e.originalLine-t.originalLine,n!==0||(n=e.originalColumn-t.originalColumn,n!==0||r)||(n=e.generatedColumn-t.generatedColumn,n!==0)||(n=e.generatedLine-t.generatedLine,n!==0)?n:tn(e.name,t.name)}Ke.compareByOriginalPositionsNoSource=ik;function ak(e,t,r){var n=e.generatedLine-t.generatedLine;return n!==0||(n=e.generatedColumn-t.generatedColumn,n!==0||r)||(n=tn(e.source,t.source),n!==0)||(n=e.originalLine-t.originalLine,n!==0)||(n=e.originalColumn-t.originalColumn,n!==0)?n:tn(e.name,t.name)}Ke.compareByGeneratedPositionsDeflated=ak;function sk(e,t,r){var n=e.generatedColumn-t.generatedColumn;return n!==0||r||(n=tn(e.source,t.source),n!==0)||(n=e.originalLine-t.originalLine,n!==0)||(n=e.originalColumn-t.originalColumn,n!==0)?n:tn(e.name,t.name)}Ke.compareByGeneratedPositionsDeflatedNoLine=sk;function tn(e,t){return e===t?0:e===null?1:t===null?-1:e>t?1:-1}function ck(e,t){var r=e.generatedLine-t.generatedLine;return r!==0||(r=e.generatedColumn-t.generatedColumn,r!==0)||(r=tn(e.source,t.source),r!==0)||(r=e.originalLine-t.originalLine,r!==0)||(r=e.originalColumn-t.originalColumn,r!==0)?r:tn(e.name,t.name)}Ke.compareByGeneratedPositionsInflated=ck;function lk(e){return JSON.parse(e.replace(/^\)]}'[^\n]*\n/,""))}Ke.parseSourceMapInput=lk;function Ak(e,t,r){if(t=t||"",e&&(e[e.length-1]!=="/"&&t[0]!=="/"&&(e+="/"),t=e+t),r){var n=_a(r);if(!n)throw new Error("sourceMapURL could not be parsed");if(n.path){var o=n.path.lastIndexOf("/");o>=0&&(n.path=n.path.substring(0,o+1))}t=GC(mi(n),t)}return lf(t)}Ke.computeSourceURL=Ak});var ff=V(qC=>{var Af=pi(),uf=Object.prototype.hasOwnProperty,lo=typeof Map<"u";function rn(){this._array=[],this._set=lo?new Map:Object.create(null)}rn.fromArray=function(t,r){for(var n=new rn,o=0,i=t.length;o<i;o++)n.add(t[o],r);return n};rn.prototype.size=function(){return lo?this._set.size:Object.getOwnPropertyNames(this._set).length};rn.prototype.add=function(t,r){var n=lo?t:Af.toSetString(t),o=lo?this.has(t):uf.call(this._set,n),i=this._array.length;(!o||r)&&this._array.push(t),o||(lo?this._set.set(t,i):this._set[n]=i)};rn.prototype.has=function(t){if(lo)return this._set.has(t);var r=Af.toSetString(t);return uf.call(this._set,r)};rn.prototype.indexOf=function(t){if(lo){var r=this._set.get(t);if(r>=0)return r}else{var n=Af.toSetString(t);if(uf.call(this._set,n))return this._set[n]}throw new Error('"'+t+'" is not in the set.')};rn.prototype.at=function(t){if(t>=0&&t<this._array.length)return this._array[t];throw new Error("No element indexed by "+t)};rn.prototype.toArray=function(){return this._array.slice()};qC.ArraySet=rn});var YC=V(VC=>{var JC=pi();function uk(e,t){var r=e.generatedLine,n=t.generatedLine,o=e.generatedColumn,i=t.generatedColumn;return n>r||n==r&&i>=o||JC.compareByGeneratedPositionsInflated(e,t)<=0}function xc(){this._array=[],this._sorted=!0,this._last={generatedLine:-1,generatedColumn:0}}xc.prototype.unsortedForEach=function(t,r){this._array.forEach(t,r)};xc.prototype.add=function(t){uk(this._last,t)?(this._last=t,this._array.push(t)):(this._sorted=!1,this._array.push(t))};xc.prototype.toArray=function(){return this._sorted||(this._array.sort(JC.compareByGeneratedPositionsInflated),this._sorted=!0),this._array};VC.MappingList=xc});var df=V(zC=>{var Ta=cf(),Fe=pi(),yc=ff().ArraySet,fk=YC().MappingList;function tr(e){e||(e={}),this._file=Fe.getArg(e,"file",null),this._sourceRoot=Fe.getArg(e,"sourceRoot",null),this._skipValidation=Fe.getArg(e,"skipValidation",!1),this._ignoreInvalidMapping=Fe.getArg(e,"ignoreInvalidMapping",!1),this._sources=new yc,this._names=new yc,this._mappings=new fk,this._sourcesContents=null}tr.prototype._version=3;tr.fromSourceMap=function(t,r){var n=t.sourceRoot,o=new tr(Object.assign(r||{},{file:t.file,sourceRoot:n}));return t.eachMapping(function(i){var a={generated:{line:i.generatedLine,column:i.generatedColumn}};i.source!=null&&(a.source=i.source,n!=null&&(a.source=Fe.relative(n,a.source)),a.original={line:i.originalLine,column:i.originalColumn},i.name!=null&&(a.name=i.name)),o.addMapping(a)}),t.sources.forEach(function(i){var a=i;n!==null&&(a=Fe.relative(n,i)),o._sources.has(a)||o._sources.add(a);var s=t.sourceContentFor(i);s!=null&&o.setSourceContent(i,s)}),o};tr.prototype.addMapping=function(t){var r=Fe.getArg(t,"generated"),n=Fe.getArg(t,"original",null),o=Fe.getArg(t,"source",null),i=Fe.getArg(t,"name",null);!this._skipValidation&&this._validateMapping(r,n,o,i)===!1||(o!=null&&(o=String(o),this._sources.has(o)||this._sources.add(o)),i!=null&&(i=String(i),this._names.has(i)||this._names.add(i)),this._mappings.add({generatedLine:r.line,generatedColumn:r.column,originalLine:n!=null&&n.line,originalColumn:n!=null&&n.column,source:o,name:i}))};tr.prototype.setSourceContent=function(t,r){var n=t;this._sourceRoot!=null&&(n=Fe.relative(this._sourceRoot,n)),r!=null?(this._sourcesContents||(this._sourcesContents=Object.create(null)),this._sourcesContents[Fe.toSetString(n)]=r):this._sourcesContents&&(delete this._sourcesContents[Fe.toSetString(n)],Object.keys(this._sourcesContents).length===0&&(this._sourcesContents=null))};tr.prototype.applySourceMap=function(t,r,n){var o=r;if(r==null){if(t.file==null)throw new Error(`SourceMapGenerator.prototype.applySourceMap requires either an explicit source file, or the source map's "file" property. Both were omitted.`);o=t.file}var i=this._sourceRoot;i!=null&&(o=Fe.relative(i,o));var a=new yc,s=new yc;this._mappings.unsortedForEach(function(c){if(c.source===o&&c.originalLine!=null){var l=t.originalPositionFor({line:c.originalLine,column:c.originalColumn});l.source!=null&&(c.source=l.source,n!=null&&(c.source=Fe.join(n,c.source)),i!=null&&(c.source=Fe.relative(i,c.source)),c.originalLine=l.line,c.originalColumn=l.column,l.name!=null&&(c.name=l.name))}var A=c.source;A!=null&&!a.has(A)&&a.add(A);var u=c.name;u!=null&&!s.has(u)&&s.add(u)},this),this._sources=a,this._names=s,t.sources.forEach(function(c){var l=t.sourceContentFor(c);l!=null&&(n!=null&&(c=Fe.join(n,c)),i!=null&&(c=Fe.relative(i,c)),this.setSourceContent(c,l))},this)};tr.prototype._validateMapping=function(t,r,n,o){if(r&&typeof r.line!="number"&&typeof r.column!="number"){var i="original.line and original.column are not numbers -- you probably meant to omit the original mapping entirely and only map the generated position. If so, pass null for the original mapping instead of an object with empty or null values.";if(this._ignoreInvalidMapping)return typeof console<"u"&&console.warn&&console.warn(i),!1;throw new Error(i)}if(!(t&&"line"in t&&"column"in t&&t.line>0&&t.column>=0&&!r&&!n&&!o)){if(t&&"line"in t&&"column"in t&&r&&"line"in r&&"column"in r&&t.line>0&&t.column>=0&&r.line>0&&r.column>=0&&n)return;var i="Invalid mapping: "+JSON.stringify({generated:t,source:n,original:r,name:o});if(this._ignoreInvalidMapping)return typeof console<"u"&&console.warn&&console.warn(i),!1;throw new Error(i)}};tr.prototype._serializeMappings=function(){for(var t=0,r=1,n=0,o=0,i=0,a=0,s="",c,l,A,u,m=this._mappings.toArray(),d=0,g=m.length;d<g;d++){if(l=m[d],c="",l.generatedLine!==r)for(t=0;l.generatedLine!==r;)c+=";",r++;else if(d>0){if(!Fe.compareByGeneratedPositionsInflated(l,m[d-1]))continue;c+=","}c+=Ta.encode(l.generatedColumn-t),t=l.generatedColumn,l.source!=null&&(u=this._sources.indexOf(l.source),c+=Ta.encode(u-a),a=u,c+=Ta.encode(l.originalLine-1-o),o=l.originalLine-1,c+=Ta.encode(l.originalColumn-n),n=l.originalColumn,l.name!=null&&(A=this._names.indexOf(l.name),c+=Ta.encode(A-i),i=A)),s+=c}return s};tr.prototype._generateSourcesContent=function(t,r){return t.map(function(n){if(!this._sourcesContents)return null;r!=null&&(n=Fe.relative(r,n));var o=Fe.toSetString(n);return Object.prototype.hasOwnProperty.call(this._sourcesContents,o)?this._sourcesContents[o]:null},this)};tr.prototype.toJSON=function(){var t={version:this._version,sources:this._sources.toArray(),names:this._names.toArray(),mappings:this._serializeMappings()};return this._file!=null&&(t.file=this._file),this._sourceRoot!=null&&(t.sourceRoot=this._sourceRoot),this._sourcesContents&&(t.sourcesContent=this._generateSourcesContent(t.sources,t.sourceRoot)),t};tr.prototype.toString=function(){return JSON.stringify(this.toJSON())};zC.SourceMapGenerator=tr});var WC=V(Ao=>{Ao.GREATEST_LOWER_BOUND=1;Ao.LEAST_UPPER_BOUND=2;function mf(e,t,r,n,o,i){var a=Math.floor((t-e)/2)+e,s=o(r,n[a],!0);return s===0?a:s>0?t-a>1?mf(a,t,r,n,o,i):i==Ao.LEAST_UPPER_BOUND?t<n.length?t:-1:a:a-e>1?mf(e,a,r,n,o,i):i==Ao.LEAST_UPPER_BOUND?a:e<0?-1:e}Ao.search=function(t,r,n,o){if(r.length===0)return-1;var i=mf(-1,r.length,t,r,n,o||Ao.GREATEST_LOWER_BOUND);if(i<0)return-1;for(;i-1>=0&&n(r[i],r[i-1],!0)===0;)--i;return i}});var XC=V(KC=>{function dk(e){function t(o,i,a){var s=o[i];o[i]=o[a],o[a]=s}function r(o,i){return Math.round(o+Math.random()*(i-o))}function n(o,i,a,s){if(a<s){var c=r(a,s),l=a-1;t(o,c,s);for(var A=o[s],u=a;u<s;u++)i(o[u],A,!1)<=0&&(l+=1,t(o,l,u));t(o,l+1,u);var m=l+1;n(o,i,a,m-1),n(o,i,m+1,s)}}return n}function mk(e){let t=dk.toString();return new Function(`return ${t}`)()(e)}var $C=new WeakMap;KC.quickSort=function(e,t,r=0){let n=$C.get(t);n===void 0&&(n=mk(t),$C.set(t,n)),n(e,t,r,e.length-1)}});var tE=V(wc=>{var F=pi(),gf=WC(),gi=ff().ArraySet,pk=cf(),ka=XC().quickSort;function Ie(e,t){var r=e;return typeof e=="string"&&(r=F.parseSourceMapInput(e)),r.sections!=null?new pr(r,t):new it(r,t)}Ie.fromSourceMap=function(e,t){return it.fromSourceMap(e,t)};Ie.prototype._version=3;Ie.prototype.__generatedMappings=null;Object.defineProperty(Ie.prototype,"_generatedMappings",{configurable:!0,enumerable:!0,get:function(){return this.__generatedMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__generatedMappings}});Ie.prototype.__originalMappings=null;Object.defineProperty(Ie.prototype,"_originalMappings",{configurable:!0,enumerable:!0,get:function(){return this.__originalMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__originalMappings}});Ie.prototype._charIsMappingSeparator=function(t,r){var n=t.charAt(r);return n===";"||n===","};Ie.prototype._parseMappings=function(t,r){throw new Error("Subclasses must implement _parseMappings")};Ie.GENERATED_ORDER=1;Ie.ORIGINAL_ORDER=2;Ie.GREATEST_LOWER_BOUND=1;Ie.LEAST_UPPER_BOUND=2;Ie.prototype.eachMapping=function(t,r,n){var o=r||null,i=n||Ie.GENERATED_ORDER,a;switch(i){case Ie.GENERATED_ORDER:a=this._generatedMappings;break;case Ie.ORIGINAL_ORDER:a=this._originalMappings;break;default:throw new Error("Unknown order of iteration.")}for(var s=this.sourceRoot,c=t.bind(o),l=this._names,A=this._sources,u=this._sourceMapURL,m=0,d=a.length;m<d;m++){var g=a[m],C=g.source===null?null:A.at(g.source);C!==null&&(C=F.computeSourceURL(s,C,u)),c({source:C,generatedLine:g.generatedLine,generatedColumn:g.generatedColumn,originalLine:g.originalLine,originalColumn:g.originalColumn,name:g.name===null?null:l.at(g.name)})}};Ie.prototype.allGeneratedPositionsFor=function(t){var r=F.getArg(t,"line"),n={source:F.getArg(t,"source"),originalLine:r,originalColumn:F.getArg(t,"column",0)};if(n.source=this._findSourceIndex(n.source),n.source<0)return[];var o=[],i=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",F.compareByOriginalPositions,gf.LEAST_UPPER_BOUND);if(i>=0){var a=this._originalMappings[i];if(t.column===void 0)for(var s=a.originalLine;a&&a.originalLine===s;)o.push({line:F.getArg(a,"generatedLine",null),column:F.getArg(a,"generatedColumn",null),lastColumn:F.getArg(a,"lastGeneratedColumn",null)}),a=this._originalMappings[++i];else for(var c=a.originalColumn;a&&a.originalLine===r&&a.originalColumn==c;)o.push({line:F.getArg(a,"generatedLine",null),column:F.getArg(a,"generatedColumn",null),lastColumn:F.getArg(a,"lastGeneratedColumn",null)}),a=this._originalMappings[++i]}return o};wc.SourceMapConsumer=Ie;function it(e,t){var r=e;typeof e=="string"&&(r=F.parseSourceMapInput(e));var n=F.getArg(r,"version"),o=F.getArg(r,"sources"),i=F.getArg(r,"names",[]),a=F.getArg(r,"sourceRoot",null),s=F.getArg(r,"sourcesContent",null),c=F.getArg(r,"mappings"),l=F.getArg(r,"file",null);if(n!=this._version)throw new Error("Unsupported version: "+n);a&&(a=F.normalize(a)),o=o.map(String).map(F.normalize).map(function(A){return a&&F.isAbsolute(a)&&F.isAbsolute(A)?F.relative(a,A):A}),this._names=gi.fromArray(i.map(String),!0),this._sources=gi.fromArray(o,!0),this._absoluteSources=this._sources.toArray().map(function(A){return F.computeSourceURL(a,A,t)}),this.sourceRoot=a,this.sourcesContent=s,this._mappings=c,this._sourceMapURL=t,this.file=l}it.prototype=Object.create(Ie.prototype);it.prototype.consumer=Ie;it.prototype._findSourceIndex=function(e){var t=e;if(this.sourceRoot!=null&&(t=F.relative(this.sourceRoot,t)),this._sources.has(t))return this._sources.indexOf(t);var r;for(r=0;r<this._absoluteSources.length;++r)if(this._absoluteSources[r]==e)return r;return-1};it.fromSourceMap=function(t,r){var n=Object.create(it.prototype),o=n._names=gi.fromArray(t._names.toArray(),!0),i=n._sources=gi.fromArray(t._sources.toArray(),!0);n.sourceRoot=t._sourceRoot,n.sourcesContent=t._generateSourcesContent(n._sources.toArray(),n.sourceRoot),n.file=t._file,n._sourceMapURL=r,n._absoluteSources=n._sources.toArray().map(function(d){return F.computeSourceURL(n.sourceRoot,d,r)});for(var a=t._mappings.toArray().slice(),s=n.__generatedMappings=[],c=n.__originalMappings=[],l=0,A=a.length;l<A;l++){var u=a[l],m=new eE;m.generatedLine=u.generatedLine,m.generatedColumn=u.generatedColumn,u.source&&(m.source=i.indexOf(u.source),m.originalLine=u.originalLine,m.originalColumn=u.originalColumn,u.name&&(m.name=o.indexOf(u.name)),c.push(m)),s.push(m)}return ka(n.__originalMappings,F.compareByOriginalPositions),n};it.prototype._version=3;Object.defineProperty(it.prototype,"sources",{get:function(){return this._absoluteSources.slice()}});function eE(){this.generatedLine=0,this.generatedColumn=0,this.source=null,this.originalLine=null,this.originalColumn=null,this.name=null}var pf=F.compareByGeneratedPositionsDeflatedNoLine;function ZC(e,t){let r=e.length,n=e.length-t;if(!(n<=1))if(n==2){let o=e[t],i=e[t+1];pf(o,i)>0&&(e[t]=i,e[t+1]=o)}else if(n<20)for(let o=t;o<r;o++)for(let i=o;i>t;i--){let a=e[i-1],s=e[i];if(pf(a,s)<=0)break;e[i-1]=s,e[i]=a}else ka(e,pf,t)}it.prototype._parseMappings=function(t,r){var n=1,o=0,i=0,a=0,s=0,c=0,l=t.length,A=0,u={},m={},d=[],g=[],C,y,I,E,b;let x=0;for(;A<l;)if(t.charAt(A)===";")n++,A++,o=0,ZC(g,x),x=g.length;else if(t.charAt(A)===",")A++;else{for(C=new eE,C.generatedLine=n,E=A;E<l&&!this._charIsMappingSeparator(t,E);E++);for(y=t.slice(A,E),I=[];A<E;)pk.decode(t,A,m),b=m.value,A=m.rest,I.push(b);if(I.length===2)throw new Error("Found a source, but no line and column");if(I.length===3)throw new Error("Found a source and line, but no column");if(C.generatedColumn=o+I[0],o=C.generatedColumn,I.length>1&&(C.source=s+I[1],s+=I[1],C.originalLine=i+I[2],i=C.originalLine,C.originalLine+=1,C.originalColumn=a+I[3],a=C.originalColumn,I.length>4&&(C.name=c+I[4],c+=I[4])),g.push(C),typeof C.originalLine=="number"){let Q=C.source;for(;d.length<=Q;)d.push(null);d[Q]===null&&(d[Q]=[]),d[Q].push(C)}}ZC(g,x),this.__generatedMappings=g;for(var w=0;w<d.length;w++)d[w]!=null&&ka(d[w],F.compareByOriginalPositionsNoSource);this.__originalMappings=[].concat(...d)};it.prototype._findMapping=function(t,r,n,o,i,a){if(t[n]<=0)throw new TypeError("Line must be greater than or equal to 1, got "+t[n]);if(t[o]<0)throw new TypeError("Column must be greater than or equal to 0, got "+t[o]);return gf.search(t,r,i,a)};it.prototype.computeColumnSpans=function(){for(var t=0;t<this._generatedMappings.length;++t){var r=this._generatedMappings[t];if(t+1<this._generatedMappings.length){var n=this._generatedMappings[t+1];if(r.generatedLine===n.generatedLine){r.lastGeneratedColumn=n.generatedColumn-1;continue}}r.lastGeneratedColumn=1/0}};it.prototype.originalPositionFor=function(t){var r={generatedLine:F.getArg(t,"line"),generatedColumn:F.getArg(t,"column")},n=this._findMapping(r,this._generatedMappings,"generatedLine","generatedColumn",F.compareByGeneratedPositionsDeflated,F.getArg(t,"bias",Ie.GREATEST_LOWER_BOUND));if(n>=0){var o=this._generatedMappings[n];if(o.generatedLine===r.generatedLine){var i=F.getArg(o,"source",null);i!==null&&(i=this._sources.at(i),i=F.computeSourceURL(this.sourceRoot,i,this._sourceMapURL));var a=F.getArg(o,"name",null);return a!==null&&(a=this._names.at(a)),{source:i,line:F.getArg(o,"originalLine",null),column:F.getArg(o,"originalColumn",null),name:a}}}return{source:null,line:null,column:null,name:null}};it.prototype.hasContentsOfAllSources=function(){return this.sourcesContent?this.sourcesContent.length>=this._sources.size()&&!this.sourcesContent.some(function(t){return t==null}):!1};it.prototype.sourceContentFor=function(t,r){if(!this.sourcesContent)return null;var n=this._findSourceIndex(t);if(n>=0)return this.sourcesContent[n];var o=t;this.sourceRoot!=null&&(o=F.relative(this.sourceRoot,o));var i;if(this.sourceRoot!=null&&(i=F.urlParse(this.sourceRoot))){var a=o.replace(/^file:\/\//,"");if(i.scheme=="file"&&this._sources.has(a))return this.sourcesContent[this._sources.indexOf(a)];if((!i.path||i.path=="/")&&this._sources.has("/"+o))return this.sourcesContent[this._sources.indexOf("/"+o)]}if(r)return null;throw new Error('"'+o+'" is not in the SourceMap.')};it.prototype.generatedPositionFor=function(t){var r=F.getArg(t,"source");if(r=this._findSourceIndex(r),r<0)return{line:null,column:null,lastColumn:null};var n={source:r,originalLine:F.getArg(t,"line"),originalColumn:F.getArg(t,"column")},o=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",F.compareByOriginalPositions,F.getArg(t,"bias",Ie.GREATEST_LOWER_BOUND));if(o>=0){var i=this._originalMappings[o];if(i.source===n.source)return{line:F.getArg(i,"generatedLine",null),column:F.getArg(i,"generatedColumn",null),lastColumn:F.getArg(i,"lastGeneratedColumn",null)}}return{line:null,column:null,lastColumn:null}};wc.BasicSourceMapConsumer=it;function pr(e,t){var r=e;typeof e=="string"&&(r=F.parseSourceMapInput(e));var n=F.getArg(r,"version"),o=F.getArg(r,"sections");if(n!=this._version)throw new Error("Unsupported version: "+n);this._sources=new gi,this._names=new gi;var i={line:-1,column:0};this._sections=o.map(function(a){if(a.url)throw new Error("Support for url field in sections not implemented.");var s=F.getArg(a,"offset"),c=F.getArg(s,"line"),l=F.getArg(s,"column");if(c<i.line||c===i.line&&l<i.column)throw new Error("Section offsets must be ordered and non-overlapping.");return i=s,{generatedOffset:{generatedLine:c+1,generatedColumn:l+1},consumer:new Ie(F.getArg(a,"map"),t)}})}pr.prototype=Object.create(Ie.prototype);pr.prototype.constructor=Ie;pr.prototype._version=3;Object.defineProperty(pr.prototype,"sources",{get:function(){for(var e=[],t=0;t<this._sections.length;t++)for(var r=0;r<this._sections[t].consumer.sources.length;r++)e.push(this._sections[t].consumer.sources[r]);return e}});pr.prototype.originalPositionFor=function(t){var r={generatedLine:F.getArg(t,"line"),generatedColumn:F.getArg(t,"column")},n=gf.search(r,this._sections,function(i,a){var s=i.generatedLine-a.generatedOffset.generatedLine;return s||i.generatedColumn-a.generatedOffset.generatedColumn}),o=this._sections[n];return o?o.consumer.originalPositionFor({line:r.generatedLine-(o.generatedOffset.generatedLine-1),column:r.generatedColumn-(o.generatedOffset.generatedLine===r.generatedLine?o.generatedOffset.generatedColumn-1:0),bias:t.bias}):{source:null,line:null,column:null,name:null}};pr.prototype.hasContentsOfAllSources=function(){return this._sections.every(function(t){return t.consumer.hasContentsOfAllSources()})};pr.prototype.sourceContentFor=function(t,r){for(var n=0;n<this._sections.length;n++){var o=this._sections[n],i=o.consumer.sourceContentFor(t,!0);if(i||i==="")return i}if(r)return null;throw new Error('"'+t+'" is not in the SourceMap.')};pr.prototype.generatedPositionFor=function(t){for(var r=0;r<this._sections.length;r++){var n=this._sections[r];if(n.consumer._findSourceIndex(F.getArg(t,"source"))!==-1){var o=n.consumer.generatedPositionFor(t);if(o){var i={line:o.line+(n.generatedOffset.generatedLine-1),column:o.column+(n.generatedOffset.generatedLine===o.line?n.generatedOffset.generatedColumn-1:0)};return i}}}return{line:null,column:null}};pr.prototype._parseMappings=function(t,r){this.__generatedMappings=[],this.__originalMappings=[];for(var n=0;n<this._sections.length;n++)for(var o=this._sections[n],i=o.consumer._generatedMappings,a=0;a<i.length;a++){var s=i[a],c=o.consumer._sources.at(s.source);c!==null&&(c=F.computeSourceURL(o.consumer.sourceRoot,c,this._sourceMapURL)),this._sources.add(c),c=this._sources.indexOf(c);var l=null;s.name&&(l=o.consumer._names.at(s.name),this._names.add(l),l=this._names.indexOf(l));var A={source:c,generatedLine:s.generatedLine+(o.generatedOffset.generatedLine-1),generatedColumn:s.generatedColumn+(o.generatedOffset.generatedLine===s.generatedLine?o.generatedOffset.generatedColumn-1:0),originalLine:s.originalLine,originalColumn:s.originalColumn,name:l};this.__generatedMappings.push(A),typeof A.originalLine=="number"&&this.__originalMappings.push(A)}ka(this.__generatedMappings,F.compareByGeneratedPositionsDeflated),ka(this.__originalMappings,F.compareByOriginalPositions)};wc.IndexedSourceMapConsumer=pr});var nE=V(rE=>{var gk=df().SourceMapGenerator,bc=pi(),hk=/(\r?\n)/,Ck=10,hi="$$$isSourceNode$$$";function Ut(e,t,r,n,o){this.children=[],this.sourceContents={},this.line=e??null,this.column=t??null,this.source=r??null,this.name=o??null,this[hi]=!0,n!=null&&this.add(n)}Ut.fromStringWithSourceMap=function(t,r,n){var o=new Ut,i=t.split(hk),a=0,s=function(){var m=g(),d=g()||"";return m+d;function g(){return a<i.length?i[a++]:void 0}},c=1,l=0,A=null;return r.eachMapping(function(m){if(A!==null)if(c<m.generatedLine)u(A,s()),c++,l=0;else{var d=i[a]||"",g=d.substr(0,m.generatedColumn-l);i[a]=d.substr(m.generatedColumn-l),l=m.generatedColumn,u(A,g),A=m;return}for(;c<m.generatedLine;)o.add(s()),c++;if(l<m.generatedColumn){var d=i[a]||"";o.add(d.substr(0,m.generatedColumn)),i[a]=d.substr(m.generatedColumn),l=m.generatedColumn}A=m},this),a<i.length&&(A&&u(A,s()),o.add(i.splice(a).join(""))),r.sources.forEach(function(m){var d=r.sourceContentFor(m);d!=null&&(n!=null&&(m=bc.join(n,m)),o.setSourceContent(m,d))}),o;function u(m,d){if(m===null||m.source===void 0)o.add(d);else{var g=n?bc.join(n,m.source):m.source;o.add(new Ut(m.originalLine,m.originalColumn,g,d,m.name))}}};Ut.prototype.add=function(t){if(Array.isArray(t))t.forEach(function(r){this.add(r)},this);else if(t[hi]||typeof t=="string")t&&this.children.push(t);else throw new TypeError("Expected a SourceNode, string, or an array of SourceNodes and strings. Got "+t);return this};Ut.prototype.prepend=function(t){if(Array.isArray(t))for(var r=t.length-1;r>=0;r--)this.prepend(t[r]);else if(t[hi]||typeof t=="string")this.children.unshift(t);else throw new TypeError("Expected a SourceNode, string, or an array of SourceNodes and strings. Got "+t);return this};Ut.prototype.walk=function(t){for(var r,n=0,o=this.children.length;n<o;n++)r=this.children[n],r[hi]?r.walk(t):r!==""&&t(r,{source:this.source,line:this.line,column:this.column,name:this.name})};Ut.prototype.join=function(t){var r,n,o=this.children.length;if(o>0){for(r=[],n=0;n<o-1;n++)r.push(this.children[n]),r.push(t);r.push(this.children[n]),this.children=r}return this};Ut.prototype.replaceRight=function(t,r){var n=this.children[this.children.length-1];return n[hi]?n.replaceRight(t,r):typeof n=="string"?this.children[this.children.length-1]=n.replace(t,r):this.children.push("".replace(t,r)),this};Ut.prototype.setSourceContent=function(t,r){this.sourceContents[bc.toSetString(t)]=r};Ut.prototype.walkSourceContents=function(t){for(var r=0,n=this.children.length;r<n;r++)this.children[r][hi]&&this.children[r].walkSourceContents(t);for(var o=Object.keys(this.sourceContents),r=0,n=o.length;r<n;r++)t(bc.fromSetString(o[r]),this.sourceContents[o[r]])};Ut.prototype.toString=function(){var t="";return this.walk(function(r){t+=r}),t};Ut.prototype.toStringWithSourceMap=function(t){var r={code:"",line:1,column:0},n=new gk(t),o=!1,i=null,a=null,s=null,c=null;return this.walk(function(l,A){r.code+=l,A.source!==null&&A.line!==null&&A.column!==null?((i!==A.source||a!==A.line||s!==A.column||c!==A.name)&&n.addMapping({source:A.source,original:{line:A.line,column:A.column},generated:{line:r.line,column:r.column},name:A.name}),i=A.source,a=A.line,s=A.column,c=A.name,o=!0):o&&(n.addMapping({generated:{line:r.line,column:r.column}}),i=null,o=!1);for(var u=0,m=l.length;u<m;u++)l.charCodeAt(u)===Ck?(r.line++,r.column=0,u+1===m?(i=null,o=!1):o&&n.addMapping({source:A.source,original:{line:A.line,column:A.column},generated:{line:r.line,column:r.column},name:A.name})):r.column++}),this.walkSourceContents(function(l,A){n.setSourceContent(l,A)}),{code:r.code,map:n}};rE.SourceNode=Ut});var oE=V(Bc=>{Bc.SourceMapGenerator=df().SourceMapGenerator;Bc.SourceMapConsumer=tE().SourceMapConsumer;Bc.SourceNode=nE().SourceNode});var iE,aE,sE=p(()=>{"use client";Gt();iE=f(R(),1),aE=(0,Ee.createSvgIcon)((0,iE.jsx)("path",{d:"M19 19H5V5h7V3H5c-1.11 0-2 .9-2 2v14c0 1.1.89 2 2 2h14c1.1 0 2-.9 2-2v-7h-2zM14 3v2h3.59l-9.83 9.83 1.41 1.41L19 6.41V10h2V3z"}),"OpenInNew")});function Qc(e){let{children:t,...r}=e;return(0,Sc.jsxs)(cE.Link,{...r,target:"_blank",rel:"noopener noreferrer",children:[t," ",(0,Sc.jsx)(aE,{fontSize:"small"})]})}var Sc,cE,lE=p(()=>{Sc=f(R(),1);sE();cE=f(O(),1)});function hf({text:e,extra:t}){let{classes:r}=Ek(),n=t?`supporting data: ${JSON.stringify(t,null,2)}`:"",o=[e,n].filter(Boolean).join(`
+"use strict";var JBrowsePluginMsaView=(()=>{var GL=Object.create;var dl=Object.defineProperty;var UL=Object.getOwnPropertyDescriptor;var HL=Object.getOwnPropertyNames;var VL=Object.getPrototypeOf,jL=Object.prototype.hasOwnProperty;var d=(e,t,r)=>()=>{if(r)throw r[0];try{return e&&(t=e(e=0)),t}catch(n){throw r=[n],n}};var z=(e,t)=>()=>{try{return t||e((t={exports:{}}).exports,t),t.exports}catch(r){throw t=0,r}},bt=(e,t)=>{for(var r in t)dl(e,r,{get:t[r],enumerable:!0})},GC=(e,t,r,n)=>{if(t&&typeof t=="object"||typeof t=="function")for(let o of HL(t))!jL.call(e,o)&&o!==r&&dl(e,o,{get:()=>t[o],enumerable:!(n=UL(t,o))||n.enumerable});return e};var p=(e,t,r)=>(r=e!=null?GL(VL(e)):{},GC(t||!e||!e.__esModule?dl(r,"default",{value:e,enumerable:!0}):r,e)),YL=e=>GC(dl({},"__esModule",{value:!0}),e);var HC=z((bV,UC)=>{UC.exports=JBrowseExports["@jbrowse/core/Plugin"]});var Hi=z((IV,VC)=>{VC.exports=JBrowseExports["@jbrowse/core/configuration"]});var Be=z((wV,jC)=>{jC.exports=JBrowseExports["@jbrowse/core/util"]});var Vt=z((SV,YC)=>{YC.exports=JBrowseExports["mobx-state-tree"]});var k=z((BV,$C)=>{$C.exports=JBrowseExports.react});function qC(e){var t,r,n="";if(typeof e=="string"||typeof e=="number")n+=e;else if(typeof e=="object")if(Array.isArray(e)){var o=e.length;for(t=0;t<o;t++)e[t]&&(r=qC(e[t]))&&(n&&(n+=" "),n+=r)}else for(r in e)e[r]&&(n&&(n+=" "),n+=r);return n}function $L(){for(var e,t,r=0,n="",o=arguments.length;r<o;r++)(e=arguments[r])&&(t=qC(e))&&(n&&(n+=" "),n+=t);return n}var Vi,ml=d(()=>{Vi=$L});function pl(e,t,r=void 0){let n={};for(let o in e){let i=e[o],a="",s=!0;for(let c=0;c<i.length;c+=1){let l=i[c];l&&(a+=(s===!0?"":" ")+t(l),s=!1,r&&r[l]&&(a+=" "+r[l]))}n[o]=a}return n}var JC=d(()=>{});var WC=d(()=>{JC()});function jt(e,...t){let r=new URL(`https://mui.com/production-error/?code=${e}`);return t.forEach(n=>r.searchParams.append("args[]",n)),`Minified MUI error #${e}; visit ${r} for the full message.`}var zC=d(()=>{});var ji=d(()=>{zC()});function Yi(e){if(typeof e!="string")throw new Error(jt(7));return e.charAt(0).toUpperCase()+e.slice(1)}var KC=d(()=>{ji()});var yd=d(()=>{KC()});var xs,XC=d(()=>{yd();xs=Yi});function Dr(e,t){let r=Array.isArray(t),n=Array.isArray(e);return KL(t)?t:XL(e)?$i(t):r&&n?WL(e,t):r!==n?$i(t):ZL(e,t)}function qL(e){let t=0,r=e.length,n=new Array(r);for(t=0;t<r;t+=1)n[t]=$i(e[t]);return n}function JL(e){let t={};for(let r in e)r==="__proto__"||r==="constructor"||r==="prototype"||(t[r]=$i(e[r]));return t}function WL(e,t){let r=e.length;for(let n=0;n<t.length;n+=1)e[r+n]=$i(t[n]);return e}function zL(e){return typeof e=="object"&&e!==null&&!(e instanceof RegExp)&&!(e instanceof Date)}function KL(e){return typeof e!="object"||e===null}function XL(e){return typeof e!="object"||e===null||e instanceof RegExp||e instanceof Date}function $i(e){return zL(e)?Array.isArray(e)?qL(e):JL(e):e}function ZL(e,t){for(let r in t)r==="__proto__"||r==="constructor"||r==="prototype"||(r in e?e[r]=Dr(e[r],t[r]):e[r]=$i(t[r]));return e}var ZC=d(()=>{});var gl=d(()=>{ZC()});function qi(e){if(e==null)return!0;for(let t in e)return!1;return!0}var ey=d(()=>{});var xd=d(()=>{ey()});var ty=z(Ce=>{"use strict";var Ed=Symbol.for("react.transitional.element"),bd=Symbol.for("react.portal"),hl=Symbol.for("react.fragment"),Cl=Symbol.for("react.strict_mode"),yl=Symbol.for("react.profiler"),xl=Symbol.for("react.consumer"),El=Symbol.for("react.context"),bl=Symbol.for("react.forward_ref"),Il=Symbol.for("react.suspense"),wl=Symbol.for("react.suspense_list"),Sl=Symbol.for("react.memo"),Bl=Symbol.for("react.lazy"),eF=Symbol.for("react.view_transition"),tF=Symbol.for("react.client.reference");function fr(e){if(typeof e=="object"&&e!==null){var t=e.$$typeof;switch(t){case Ed:switch(e=e.type,e){case hl:case yl:case Cl:case Il:case wl:case eF:return e;default:switch(e=e&&e.$$typeof,e){case El:case bl:case Bl:case Sl:return e;case xl:return e;default:return t}}case bd:return t}}}Ce.ContextConsumer=xl;Ce.ContextProvider=El;Ce.Element=Ed;Ce.ForwardRef=bl;Ce.Fragment=hl;Ce.Lazy=Bl;Ce.Memo=Sl;Ce.Portal=bd;Ce.Profiler=yl;Ce.StrictMode=Cl;Ce.Suspense=Il;Ce.SuspenseList=wl;Ce.isContextConsumer=function(e){return fr(e)===xl};Ce.isContextProvider=function(e){return fr(e)===El};Ce.isElement=function(e){return typeof e=="object"&&e!==null&&e.$$typeof===Ed};Ce.isForwardRef=function(e){return fr(e)===bl};Ce.isFragment=function(e){return fr(e)===hl};Ce.isLazy=function(e){return fr(e)===Bl};Ce.isMemo=function(e){return fr(e)===Sl};Ce.isPortal=function(e){return fr(e)===bd};Ce.isProfiler=function(e){return fr(e)===yl};Ce.isStrictMode=function(e){return fr(e)===Cl};Ce.isSuspense=function(e){return fr(e)===Il};Ce.isSuspenseList=function(e){return fr(e)===wl};Ce.isValidElementType=function(e){return typeof e=="string"||typeof e=="function"||e===hl||e===yl||e===Cl||e===Il||e===wl||typeof e=="object"&&e!==null&&(e.$$typeof===Bl||e.$$typeof===Sl||e.$$typeof===El||e.$$typeof===xl||e.$$typeof===bl||e.$$typeof===tF||e.getModuleId!==void 0)};Ce.typeOf=fr});var ny=z((qV,ry)=>{"use strict";ry.exports=ty()});function Nr(e){if(typeof e!="object"||e===null)return!1;let t=Object.getPrototypeOf(e);return(t===null||t===Object.prototype||Object.getPrototypeOf(t)===null)&&!(Symbol.toStringTag in e)&&!(Symbol.iterator in e)}function oy(e){if(Id.isValidElement(e)||(0,wd.isValidElementType)(e)||!Nr(e))return e;let t={};return Object.keys(e).forEach(r=>{t[r]=oy(e[r])}),t}function We(e,t,r={clone:!0}){let n=r.clone?{...e}:e;return Nr(e)&&Nr(t)&&Object.keys(t).forEach(o=>{Id.isValidElement(t[o])||(0,wd.isValidElementType)(t[o])?n[o]=t[o]:Nr(t[o])&&Object.prototype.hasOwnProperty.call(e,o)&&Nr(e[o])?n[o]=We(e[o],t[o],r):r.clone?n[o]=Nr(t[o])?oy(t[o]):t[o]:n[o]=t[o]}),n}var Id,wd,Sd=d(()=>{Id=p(k(),1),wd=p(ny(),1)});var Mn=d(()=>{Sd();Sd()});function vl(e,t){if(!e.containerQueries||!rF(t))return t;let r=[];for(let o in t)o.startsWith("@container")&&r.push(o);r.sort((o,i)=>+(o.match(iy)?.[1]||0)-+(i.match(iy)?.[1]||0));let n=t;for(let o=0;o<r.length;o+=1){let i=r[o],a=n[i];delete n[i],n[i]=a}return n}function rF(e){for(let t in e)if(t.startsWith("@container"))return!0;return!1}function Tl(e,t){return t==="@"||t.startsWith("@")&&(e.some(r=>t.startsWith(`@${r}`))||!!t.match(/^@\d/))}function Bd(e,t){let r=t.match(/^@([^/]+)?\/?(.+)?$/);if(!r)return null;let[,n,o]=r,i=Number.isNaN(+n)?n||0:+n;return e.containerQueries(o).up(i)}function Ql(e){let t=(i,a)=>i.replace("@media",a?`@container ${a}`:"@container");function r(i,a){i.up=(...s)=>t(e.breakpoints.up(...s),a),i.down=(...s)=>t(e.breakpoints.down(...s),a),i.between=(...s)=>t(e.breakpoints.between(...s),a),i.only=(...s)=>t(e.breakpoints.only(...s),a),i.not=(...s)=>{let c=t(e.breakpoints.not(...s),a);return c.includes("not all and")?c.replace("not all and ","").replace("min-width:","width<").replace("max-width:","width>").replace("and","or"):c}}let n={},o=i=>(r(n,i),n);return r(o),{...e,containerQueries:o}}var iy,vd=d(()=>{iy=/min-width:\s*([0-9.]+)/});var Ml=d(()=>{vd();vd()});function Es(e){let{values:t={xs:0,sm:600,md:900,lg:1200,xl:1536},unit:r="px",step:n=5,...o}=e,i=nF(t),a=Object.keys(i);function s(f){return`@media (min-width:${typeof t[f]=="number"?t[f]:f}${r})`}function c(f){return`@media (max-width:${(typeof t[f]=="number"?t[f]:f)-n/100}${r})`}function l(f,g){let y=a.indexOf(g);return`@media (min-width:${typeof t[f]=="number"?t[f]:f}${r}) and (max-width:${(y!==-1&&typeof t[a[y]]=="number"?t[a[y]]:g)-n/100}${r})`}function u(f){return a.indexOf(f)+1<a.length?l(f,a[a.indexOf(f)+1]):s(f)}function A(f){let g=a.indexOf(f);return g===0?s(a[1]):g===a.length-1?c(a[g]):l(f,a[a.indexOf(f)+1]).replace("@media","@media not all and")}let m=[];for(let f=0;f<a.length;f+=1)m.push(s(a[f]));return{keys:a,values:i,up:s,down:c,between:l,only:u,not:A,unit:r,internal_mediaKeys:m,...o}}var nF,Td=d(()=>{nF=e=>{let t=Object.keys(e).map(r=>({key:r,val:e[r]}))||[];return t.sort((r,n)=>r.val-n.val),t.reduce((r,n)=>({...r,[n.key]:n.val}),{})}});function rn(e,t,r){let n={};return Ji(n,e.theme,t,(o,i,a)=>{let s=r(i,a);o?n[o]=s:Dr(n,s)})}function Ji(e,t,r,n){if(t??=oF,Array.isArray(r)){let o=t.breakpoints??bs;for(let i=0;i<r.length;i+=1)Qd(e,o.up(o.keys[i]),r[i],void 0,n);return e}if(typeof r=="object"){let o=t.breakpoints??bs,i=o.values??Is;for(let a in r)if(Tl(o.keys,a)){let s=Bd(t.containerQueries?t:iF,a);s&&Qd(e,s,r[a],a,n)}else if(a in i){let s=o.up(a);Qd(e,s,r[a],a,n)}else{let s=a;e[s]=r[s]}return e}return n(void 0,r),e}function Qd(e,t,r,n,o){e[t]??={},o(t,r,n)}function ay(e=bs){let{internal_mediaKeys:t}=e,r={};for(let n=0;n<t.length;n+=1)r[t[n]]={};return r}function Md(e,t){let r=e.internal_mediaKeys;for(let n=0;n<r.length;n+=1){let o=r[n];qi(t[o])&&delete t[o]}return t}function sy(e,t){if(Array.isArray(t))return!0;if(typeof t=="object"&&t!==null){for(let n=0;n<e.keys.length;n+=1)if(e.keys[n]in t)return!0;let r=Object.keys(t);for(let n=0;n<r.length;n+=1)if(Tl(e.keys,r[n]))return!0}return!1}var oF,Is,bs,iF,cy=d(()=>{xd();gl();Ml();Td();oF={},Is={xs:0,sm:600,md:900,lg:1200,xl:1536},bs=Es({values:Is}),iF={containerQueries:e=>({up:t=>{let r=typeof t=="number"?t:Is[t]||t;return typeof r=="number"&&(r=`${r}px`),e?`@container ${e} (min-width:${r})`:`@container (min-width:${r})`}})}});var eo=d(()=>{cy()});function _d(e,t,r,n){let o;return typeof e=="function"?o=e(r):Array.isArray(e)?o=e[r]||r:typeof r=="string"?o=Wi(e,r,!0,n)||r:o=r,t&&(o=t(o,r,e)),o}function Wi(e,t,r=!0,n=void 0){if(!e||!t)return null;let o=t.split(".");if(e.vars&&r){let i=ly(e.vars,o,n);if(i!=null)return i}return ly(e,o,n)}function ly(e,t,r=void 0){let n,o=e,i=0;for(;i<t.length;){if(o==null)return o;n=o,o=o[t[i]],i+=1}if(r&&o===void 0){let a=t[t.length-1],s=`${r}${a==="default"?"":Yi(a)}`;return n?.[s]}return o}function j(e){let{prop:t,cssProperty:r=e.prop,themeKey:n,transform:o}=e,i=a=>{if(a[t]==null)return null;let s=a[t],c=a.theme,l=Wi(c,n)||{};return rn(a,s,A=>{let m=_d(l,o,A,t);return r===!1?m:{[r]:m}})};return i.propTypes={},i.filterProps=[t],i}var kd=d(()=>{yd();eo()});var nn=d(()=>{kd();kd()});function Fo(e,t,r,n){let o=Wi(e,t,!0)??r;return typeof o=="number"||typeof o=="string"?i=>typeof i=="string"?i:typeof o=="string"?o.startsWith("var(")&&i===0?0:o.startsWith("var(")&&i===1?o:`calc(${i} * ${o})`:o*i:Array.isArray(o)?i=>{if(typeof i=="string")return i;let a=Math.abs(i),s=o[a];return i>=0?s:typeof s=="number"?-s:typeof s=="string"&&s.startsWith("var(")?`calc(-1 * ${s})`:`-${s}`}:typeof o=="function"?o:()=>{}}function Ss(e){return Fo(e,"spacing",8,"spacing")}function Po(e,t){return typeof t=="string"||t==null?t:e(t)}function Rd(e,t){let r=e.theme??sF,n=r?.internal_cache?.unarySpacing??Ss(r),o={};for(let i in e){if(!t.has(i))continue;let a=ws[i]??(Ay[0]=i,Ay),s=e[i];Ji(o,e.theme,s,(c,l)=>{let u=c?o[c]:o;for(let A=0;A<a.length;A+=1)u[a[A]]=Po(n,l)})}return o}function Ld(e){return Rd(e,Dd)}function Fd(e){return Rd(e,Nd)}function my(e){return Rd(e,dy)}var sF,_l,uy,fy,ws,Dd,Nd,dy,Ay,He,Ve,py=d(()=>{eo();nn();sF={internal_cache:{}},_l={m:"margin",p:"padding"},uy={t:"Top",r:"Right",b:"Bottom",l:"Left",x:["Left","Right"],y:["Top","Bottom"]},fy={marginX:"mx",marginY:"my",paddingX:"px",paddingY:"py"},ws={};for(let e in _l)ws[e]=[_l[e]];for(let e in _l)for(let t in uy){let r=_l[e],n=uy[t],o=Array.isArray(n)?n.map(i=>r+i):[r+n];ws[e+t]=o}for(let e in fy)ws[e]=ws[fy[e]];Dd=new Set(["m","mt","mr","mb","ml","mx","my","margin","marginTop","marginRight","marginBottom","marginLeft","marginX","marginY","marginInline","marginInlineStart","marginInlineEnd","marginBlock","marginBlockStart","marginBlockEnd"]),Nd=new Set(["p","pt","pr","pb","pl","px","py","padding","paddingTop","paddingRight","paddingBottom","paddingLeft","paddingX","paddingY","paddingInline","paddingInlineStart","paddingInlineEnd","paddingBlock","paddingBlockStart","paddingBlockEnd"]),dy=new Set([...Dd,...Nd]);Ay=[""];Ld.propTypes={};Ld.filterProps=Dd;He=Ld;Fd.propTypes={};Fd.filterProps=Nd;Ve=Fd;my.propTypes={};my.filterProps=dy});var Oo=d(()=>{py()});function cF(...e){let t=e.reduce((n,o)=>(o.filterProps.forEach(i=>{n[i]=o}),n),{}),r=n=>{let o={};for(let i in n)t[i]&&Dr(o,t[i](n));return o};return r.propTypes={},r.filterProps=e.reduce((n,o)=>n.concat(o.filterProps),[]),r}var _t,gy=d(()=>{gl();_t=cF});var to=d(()=>{gy()});function zt(e){return typeof e!="number"?e:`${e}px solid`}function Ar(e,t){return j({prop:e,themeKey:"borders",transform:t})}var lF,uF,fF,AF,dF,mF,pF,gF,hF,CF,yF,xF,Bs,Tj,hy=d(()=>{nn();to();Oo();eo();lF=Ar("border",zt),uF=Ar("borderTop",zt),fF=Ar("borderRight",zt),AF=Ar("borderBottom",zt),dF=Ar("borderLeft",zt),mF=Ar("borderColor"),pF=Ar("borderTopColor"),gF=Ar("borderRightColor"),hF=Ar("borderBottomColor"),CF=Ar("borderLeftColor"),yF=Ar("outline",zt),xF=Ar("outlineColor"),Bs=e=>{if(e.borderRadius!==void 0&&e.borderRadius!==null){let t=Fo(e.theme,"shape.borderRadius",4,"borderRadius"),r=n=>({borderRadius:Po(t,n)});return rn(e,e.borderRadius,r)}return null};Bs.propTypes={};Bs.filterProps=["borderRadius"];Tj=_t(lF,uF,fF,AF,dF,mF,pF,gF,hF,CF,Bs,yF,xF)});var Pd=d(()=>{hy()});var vs,Ts,Qs,EF,bF,IF,wF,SF,BF,vF,TF,QF,Lj,Cy=d(()=>{nn();to();Oo();eo();vs=e=>{if(e.gap!==void 0&&e.gap!==null){let t=Fo(e.theme,"spacing",8,"gap"),r=n=>({gap:Po(t,n)});return rn(e,e.gap,r)}return null};vs.propTypes={};vs.filterProps=["gap"];Ts=e=>{if(e.columnGap!==void 0&&e.columnGap!==null){let t=Fo(e.theme,"spacing",8,"columnGap"),r=n=>({columnGap:Po(t,n)});return rn(e,e.columnGap,r)}return null};Ts.propTypes={};Ts.filterProps=["columnGap"];Qs=e=>{if(e.rowGap!==void 0&&e.rowGap!==null){let t=Fo(e.theme,"spacing",8,"rowGap"),r=n=>({rowGap:Po(t,n)});return rn(e,e.rowGap,r)}return null};Qs.propTypes={};Qs.filterProps=["rowGap"];EF=j({prop:"gridColumn"}),bF=j({prop:"gridRow"}),IF=j({prop:"gridAutoFlow"}),wF=j({prop:"gridAutoColumns"}),SF=j({prop:"gridAutoRows"}),BF=j({prop:"gridTemplateColumns"}),vF=j({prop:"gridTemplateRows"}),TF=j({prop:"gridTemplateAreas"}),QF=j({prop:"gridArea"}),Lj=_t(vs,Ts,Qs,EF,bF,IF,wF,SF,BF,vF,TF,QF)});var Od=d(()=>{Cy()});function Go(e,t){return t==="grey"?t:e}var MF,_F,kF,Hj,yy=d(()=>{nn();to();MF=j({prop:"color",themeKey:"palette",transform:Go}),_F=j({prop:"bgcolor",cssProperty:"backgroundColor",themeKey:"palette",transform:Go}),kF=j({prop:"backgroundColor",themeKey:"palette",transform:Go}),Hj=_t(MF,_F,kF)});var Gd=d(()=>{yy()});function Yt(e){return e<=1&&e!==0?`${e*100}%`:e}var DF,NF,kl,RF,LF,FF,PF,Wj,zj,OF,Kj,xy=d(()=>{nn();to();eo();eo();DF=Is;NF=j({prop:"width",transform:Yt}),kl=e=>{if(e.maxWidth!==void 0&&e.maxWidth!==null){let t=r=>{let n=e.theme?.breakpoints?.values?.[r]||DF[r];return n?e.theme?.breakpoints?.unit!=="px"?{maxWidth:`${n}${e.theme.breakpoints.unit}`}:{maxWidth:n}:{maxWidth:Yt(r)}};return rn(e,e.maxWidth,t)}return null};kl.filterProps=["maxWidth"];RF=j({prop:"minWidth",transform:Yt}),LF=j({prop:"height",transform:Yt}),FF=j({prop:"maxHeight",transform:Yt}),PF=j({prop:"minHeight",transform:Yt}),Wj=j({prop:"size",cssProperty:"width",transform:Yt}),zj=j({prop:"size",cssProperty:"height",transform:Yt}),OF=j({prop:"boxSizing"}),Kj=_t(NF,kl,RF,LF,FF,PF,OF)});var Ud=d(()=>{xy()});var GF,_n,Dl=d(()=>{Oo();Pd();Od();Gd();Ud();GF={border:{themeKey:"borders",transform:zt},borderTop:{themeKey:"borders",transform:zt},borderRight:{themeKey:"borders",transform:zt},borderBottom:{themeKey:"borders",transform:zt},borderLeft:{themeKey:"borders",transform:zt},borderColor:{themeKey:"palette"},borderTopColor:{themeKey:"palette"},borderRightColor:{themeKey:"palette"},borderBottomColor:{themeKey:"palette"},borderLeftColor:{themeKey:"palette"},outline:{themeKey:"borders",transform:zt},outlineColor:{themeKey:"palette"},borderRadius:{themeKey:"shape.borderRadius",style:Bs},color:{themeKey:"palette",transform:Go},bgcolor:{themeKey:"palette",cssProperty:"backgroundColor",transform:Go},backgroundColor:{themeKey:"palette",transform:Go},p:{style:Ve},pt:{style:Ve},pr:{style:Ve},pb:{style:Ve},pl:{style:Ve},px:{style:Ve},py:{style:Ve},padding:{style:Ve},paddingTop:{style:Ve},paddingRight:{style:Ve},paddingBottom:{style:Ve},paddingLeft:{style:Ve},paddingX:{style:Ve},paddingY:{style:Ve},paddingInline:{style:Ve},paddingInlineStart:{style:Ve},paddingInlineEnd:{style:Ve},paddingBlock:{style:Ve},paddingBlockStart:{style:Ve},paddingBlockEnd:{style:Ve},m:{style:He},mt:{style:He},mr:{style:He},mb:{style:He},ml:{style:He},mx:{style:He},my:{style:He},margin:{style:He},marginTop:{style:He},marginRight:{style:He},marginBottom:{style:He},marginLeft:{style:He},marginX:{style:He},marginY:{style:He},marginInline:{style:He},marginInlineStart:{style:He},marginInlineEnd:{style:He},marginBlock:{style:He},marginBlockStart:{style:He},marginBlockEnd:{style:He},displayPrint:{cssProperty:!1,transform:e=>({"@media print":{display:e}})},display:{},overflow:{},textOverflow:{},visibility:{},whiteSpace:{},flexBasis:{},flexDirection:{},flexWrap:{},justifyContent:{},alignItems:{},alignContent:{},order:{},flex:{},flexGrow:{},flexShrink:{},alignSelf:{},justifyItems:{},justifySelf:{},gap:{style:vs},rowGap:{style:Qs},columnGap:{style:Ts},gridColumn:{},gridRow:{},gridAutoFlow:{},gridAutoColumns:{},gridAutoRows:{},gridTemplateColumns:{},gridTemplateRows:{},gridTemplateAreas:{},gridArea:{},position:{},zIndex:{themeKey:"zIndex"},top:{},right:{},bottom:{},left:{},boxShadow:{themeKey:"shadows"},width:{transform:Yt},maxWidth:{style:kl},minWidth:{transform:Yt},height:{transform:Yt},maxHeight:{transform:Yt},minHeight:{transform:Yt},boxSizing:{},font:{themeKey:"font"},fontFamily:{themeKey:"typography"},fontSize:{themeKey:"typography"},fontStyle:{themeKey:"typography"},fontWeight:{themeKey:"typography"},letterSpacing:{},textTransform:{},lineHeight:{},textAlign:{},typography:{cssProperty:!1,themeKey:"typography"}},_n=GF});function HF(){function e(t){if(!t.sx)return null;let{sx:r,theme:n=UF,nested:o}=t,i=n.unstable_sxConfig??_n,a={sx:null,theme:n,nested:!0};function s(c){let l=c;if(typeof c=="function")l=c(n);else if(typeof c!="object")return c;if(!l)return null;let u=n.breakpoints??bs,A=ay(u);for(let m in l){let f=VF(l[m],n);if(f!=null){if(typeof f!="object"){Ey(A,m,f,n,i);continue}if(i[m]){Ey(A,m,f,n,i);continue}sy(u,f)?Ji(A,t.theme,f,(g,y)=>{A[g][m]=y}):(a.sx=f,A[m]=e(a))}}return!o&&n.modularCssLayers?{"@layer sx":vl(n,Md(u,A))}:vl(n,Md(u,A))}return Array.isArray(r)?r.map(s):s(r)}return e.filterProps=["sx"],e}function Ey(e,t,r,n,o){let i=o[t];if(!i){e[t]=r;return}if(r==null)return;let{themeKey:a}=i;if(a==="typography"&&r==="inherit"){e[t]=r;return}let{style:s}=i;if(s){Dr(e,s({[t]:r,theme:n}));return}let{cssProperty:c=t,transform:l}=i,u=Wi(n,a);Ji(e,n,r,(A,m)=>{let f=_d(u,l,m,t);c===!1?A?Dr(e[A],f):Dr(e,f):A?e[A][c]=f:e[c]=f})}function VF(e,t){return typeof e=="function"?e(t):e}var UF,dr,Hd=d(()=>{gl();nn();eo();Ml();Dl();UF={};dr=HF()});var Ms=d(()=>{Hd();Dl()});function _s(){return _s=Object.assign?Object.assign.bind():function(e){for(var t=1;t<arguments.length;t++){var r=arguments[t];for(var n in r)({}).hasOwnProperty.call(r,n)&&(e[n]=r[n])}return e},_s.apply(null,arguments)}var ks=d(()=>{});function YF(e){if(e.sheet)return e.sheet;for(var t=0;t<document.styleSheets.length;t++)if(document.styleSheets[t].ownerNode===e)return document.styleSheets[t]}function $F(e){var t=document.createElement("style");return t.setAttribute("data-emotion",e.key),e.nonce!==void 0&&t.setAttribute("nonce",e.nonce),t.appendChild(document.createTextNode("")),t.setAttribute("data-s",""),t}var jF,by,Iy=d(()=>{jF=!1;by=(function(){function e(r){var n=this;this._insertTag=function(o){var i;n.tags.length===0?n.insertionPoint?i=n.insertionPoint.nextSibling:n.prepend?i=n.container.firstChild:i=n.before:i=n.tags[n.tags.length-1].nextSibling,n.container.insertBefore(o,i),n.tags.push(o)},this.isSpeedy=r.speedy===void 0?!jF:r.speedy,this.tags=[],this.ctr=0,this.nonce=r.nonce,this.key=r.key,this.container=r.container,this.prepend=r.prepend,this.insertionPoint=r.insertionPoint,this.before=null}var t=e.prototype;return t.hydrate=function(n){n.forEach(this._insertTag)},t.insert=function(n){this.ctr%(this.isSpeedy?65e3:1)===0&&this._insertTag($F(this));var o=this.tags[this.tags.length-1];if(this.isSpeedy){var i=YF(o);try{i.insertRule(n,i.cssRules.length)}catch{}}else o.appendChild(document.createTextNode(n));this.ctr++},t.flush=function(){this.tags.forEach(function(n){var o;return(o=n.parentNode)==null?void 0:o.removeChild(n)}),this.tags=[],this.ctr=0},e})()});var At,Ds,ne,Nl,zi,Ki,wy,Rl,Sy,Ll=d(()=>{At="-ms-",Ds="-moz-",ne="-webkit-",Nl="comm",zi="rule",Ki="decl",wy="@import",Rl="@keyframes",Sy="@layer"});function Ty(e,t){return je(e,0)^45?(((t<<2^je(e,0))<<2^je(e,1))<<2^je(e,2))<<2^je(e,3):0}function Fl(e){return e.trim()}function Vd(e,t){return(e=t.exec(e))?e[0]:e}function ee(e,t,r){return e.replace(t,r)}function Ns(e,t){return e.indexOf(t)}function je(e,t){return e.charCodeAt(t)|0}function ro(e,t,r){return e.slice(t,r)}function kt(e){return e.length}function Xi(e){return e.length}function Zi(e,t){return t.push(e),e}function jd(e,t){return e.map(t).join("")}var By,Uo,vy,ea=d(()=>{By=Math.abs,Uo=String.fromCharCode,vy=Object.assign});function Rs(e,t,r,n,o,i,a){return{value:e,root:t,parent:r,type:n,props:o,children:i,line:Pl,column:ta,length:a,return:""}}function oa(e,t){return vy(Rs("",null,null,"",null,null,0),e,{length:-e.length},t)}function My(){return ze}function _y(){return ze=Dt>0?je(na,--Dt):0,ta--,ze===10&&(ta=1,Pl--),ze}function Nt(){return ze=Dt<Qy?je(na,Dt++):0,ta++,ze===10&&(ta=1,Pl++),ze}function mr(){return je(na,Dt)}function Ls(){return Dt}function ia(e,t){return ro(na,e,t)}function ra(e){switch(e){case 0:case 9:case 10:case 13:case 32:return 5;case 33:case 43:case 44:case 47:case 62:case 64:case 126:case 59:case 123:case 125:return 4;case 58:return 3;case 34:case 39:case 40:case 91:return 2;case 41:case 93:return 1}return 0}function Ol(e){return Pl=ta=1,Qy=kt(na=e),Dt=0,[]}function Gl(e){return na="",e}function aa(e){return Fl(ia(Dt-1,Yd(e===91?e+2:e===40?e+1:e)))}function ky(e){for(;(ze=mr())&&ze<33;)Nt();return ra(e)>2||ra(ze)>3?"":" "}function Dy(e,t){for(;--t&&Nt()&&!(ze<48||ze>102||ze>57&&ze<65||ze>70&&ze<97););return ia(e,Ls()+(t<6&&mr()==32&&Nt()==32))}function Yd(e){for(;Nt();)switch(ze){case e:return Dt;case 34:case 39:e!==34&&e!==39&&Yd(ze);break;case 40:e===41&&Yd(e);break;case 92:Nt();break}return Dt}function Ny(e,t){for(;Nt()&&e+ze!==57;)if(e+ze===84&&mr()===47)break;return"/*"+ia(t,Dt-1)+"*"+Uo(e===47?e:Nt())}function Ry(e){for(;!ra(mr());)Nt();return ia(e,Dt)}var Pl,ta,Qy,Dt,ze,na,$d=d(()=>{ea();Pl=1,ta=1,Qy=0,Dt=0,ze=0,na=""});function Py(e){return Gl(Ul("",null,null,null,[""],e=Ol(e),0,[0],e))}function Ul(e,t,r,n,o,i,a,s,c){for(var l=0,u=0,A=a,m=0,f=0,g=0,y=1,E=1,b=1,x=0,B="",I=o,w=i,S=n,v=B;E;)switch(g=x,x=Nt()){case 40:if(g!=108&&je(v,A-1)==58){Ns(v+=ee(aa(x),"&","&\f"),"&\f")!=-1&&(b=-1);break}case 34:case 39:case 91:v+=aa(x);break;case 9:case 10:case 13:case 32:v+=ky(g);break;case 92:v+=Dy(Ls()-1,7);continue;case 47:switch(mr()){case 42:case 47:Zi(qF(Ny(Nt(),Ls()),t,r),c);break;default:v+="/"}break;case 123*y:s[l++]=kt(v)*b;case 125*y:case 59:case 0:switch(x){case 0:case 125:E=0;case 59+u:b==-1&&(v=ee(v,/\f/g,"")),f>0&&kt(v)-A&&Zi(f>32?Fy(v+";",n,r,A-1):Fy(ee(v," ","")+";",n,r,A-2),c);break;case 59:v+=";";default:if(Zi(S=Ly(v,t,r,l,u,o,s,B,I=[],w=[],A),i),x===123)if(u===0)Ul(v,t,S,S,I,i,A,s,w);else switch(m===99&&je(v,3)===110?100:m){case 100:case 108:case 109:case 115:Ul(e,S,S,n&&Zi(Ly(e,S,S,0,0,o,s,B,o,I=[],A),w),o,w,A,s,n?I:w);break;default:Ul(v,S,S,S,[""],w,0,s,w)}}l=u=f=0,y=b=1,B=v="",A=a;break;case 58:A=1+kt(v),f=g;default:if(y<1){if(x==123)--y;else if(x==125&&y++==0&&_y()==125)continue}switch(v+=Uo(x),x*y){case 38:b=u>0?1:(v+="\f",-1);break;case 44:s[l++]=(kt(v)-1)*b,b=1;break;case 64:mr()===45&&(v+=aa(Nt())),m=mr(),u=A=kt(B=v+=Ry(Ls())),x++;break;case 45:g===45&&kt(v)==2&&(y=0)}}return i}function Ly(e,t,r,n,o,i,a,s,c,l,u){for(var A=o-1,m=o===0?i:[""],f=Xi(m),g=0,y=0,E=0;g<n;++g)for(var b=0,x=ro(e,A+1,A=By(y=a[g])),B=e;b<f;++b)(B=Fl(y>0?m[b]+" "+x:ee(x,/&\f/g,m[b])))&&(c[E++]=B);return Rs(e,t,r,o===0?zi:s,c,l,u)}function qF(e,t,r){return Rs(e,t,r,Nl,Uo(My()),ro(e,2,-2),0)}function Fy(e,t,r,n){return Rs(e,t,r,Ki,ro(e,0,n),ro(e,n+1,-1),n)}var Oy=d(()=>{Ll();ea();$d()});var Gy=d(()=>{});function Ho(e,t){for(var r="",n=Xi(e),o=0;o<n;o++)r+=t(e[o],o,e,t)||"";return r}function Uy(e,t,r,n){switch(e.type){case Sy:if(e.children.length)break;case wy:case Ki:return e.return=e.return||e.value;case Nl:return"";case Rl:return e.return=e.value+"{"+Ho(e.children,n)+"}";case zi:e.value=e.props.join(",")}return kt(r=Ho(e.children,n))?e.return=e.value+"{"+r+"}":""}var Hy=d(()=>{Ll();ea()});function Vy(e){var t=Xi(e);return function(r,n,o,i){for(var a="",s=0;s<t;s++)a+=e[s](r,n,o,i)||"";return a}}function jy(e){return function(t){t.root||(t=t.return)&&e(t)}}var Yy=d(()=>{ea()});var $y=d(()=>{Ll();ea();Oy();Gy();$d();Hy();Yy()});var Hl=d(()=>{});function Vl(e){var t=Object.create(null);return function(r){return t[r]===void 0&&(t[r]=e(r)),t[r]}}var jl=d(()=>{});function Jy(e,t){switch(Ty(e,t)){case 5103:return ne+"print-"+e+e;case 5737:case 4201:case 3177:case 3433:case 1641:case 4457:case 2921:case 5572:case 6356:case 5844:case 3191:case 6645:case 3005:case 6391:case 5879:case 5623:case 6135:case 4599:case 4855:case 4215:case 6389:case 5109:case 5365:case 5621:case 3829:return ne+e+e;case 5349:case 4246:case 4810:case 6968:case 2756:return ne+e+Ds+e+At+e+e;case 6828:case 4268:return ne+e+At+e+e;case 6165:return ne+e+At+"flex-"+e+e;case 5187:return ne+e+ee(e,/(\w+).+(:[^]+)/,ne+"box-$1$2"+At+"flex-$1$2")+e;case 5443:return ne+e+At+"flex-item-"+ee(e,/flex-|-self/,"")+e;case 4675:return ne+e+At+"flex-line-pack"+ee(e,/align-content|flex-|-self/,"")+e;case 5548:return ne+e+At+ee(e,"shrink","negative")+e;case 5292:return ne+e+At+ee(e,"basis","preferred-size")+e;case 6060:return ne+"box-"+ee(e,"-grow","")+ne+e+At+ee(e,"grow","positive")+e;case 4554:return ne+ee(e,/([^-])(transform)/g,"$1"+ne+"$2")+e;case 6187:return ee(ee(ee(e,/(zoom-|grab)/,ne+"$1"),/(image-set)/,ne+"$1"),e,"")+e;case 5495:case 3959:return ee(e,/(image-set\([^]*)/,ne+"$1$`$1");case 4968:return ee(ee(e,/(.+:)(flex-)?(.*)/,ne+"box-pack:$3"+At+"flex-pack:$3"),/s.+-b[^;]+/,"justify")+ne+e+e;case 4095:case 3583:case 4068:case 2532:return ee(e,/(.+)-inline(.+)/,ne+"$1$2")+e;case 8116:case 7059:case 5753:case 5535:case 5445:case 5701:case 4933:case 4677:case 5533:case 5789:case 5021:case 4765:if(kt(e)-1-t>6)switch(je(e,t+1)){case 109:if(je(e,t+4)!==45)break;case 102:return ee(e,/(.+:)(.+)-([^]+)/,"$1"+ne+"$2-$3$1"+Ds+(je(e,t+3)==108?"$3":"$2-$3"))+e;case 115:return~Ns(e,"stretch")?Jy(ee(e,"stretch","fill-available"),t)+e:e}break;case 4949:if(je(e,t+1)!==115)break;case 6444:switch(je(e,kt(e)-3-(~Ns(e,"!important")&&10))){case 107:return ee(e,":",":"+ne)+e;case 101:return ee(e,/(.+:)([^;!]+)(;|!.+)?/,"$1"+ne+(je(e,14)===45?"inline-":"")+"box$3$1"+ne+"$2$3$1"+At+"$2box$3")+e}break;case 5936:switch(je(e,t+11)){case 114:return ne+e+At+ee(e,/[svh]\w+-[tblr]{2}/,"tb")+e;case 108:return ne+e+At+ee(e,/[svh]\w+-[tblr]{2}/,"tb-rl")+e;case 45:return ne+e+At+ee(e,/[svh]\w+-[tblr]{2}/,"lr")+e}return ne+e+At+e+e}return e}var JF,WF,zF,qy,KF,XF,ZF,e5,Wy,qd=d(()=>{Iy();$y();Hl();jl();JF=function(t,r,n){for(var o=0,i=0;o=i,i=mr(),o===38&&i===12&&(r[n]=1),!ra(i);)Nt();return ia(t,Dt)},WF=function(t,r){var n=-1,o=44;do switch(ra(o)){case 0:o===38&&mr()===12&&(r[n]=1),t[n]+=JF(Dt-1,r,n);break;case 2:t[n]+=aa(o);break;case 4:if(o===44){t[++n]=mr()===58?"&\f":"",r[n]=t[n].length;break}default:t[n]+=Uo(o)}while(o=Nt());return t},zF=function(t,r){return Gl(WF(Ol(t),r))},qy=new WeakMap,KF=function(t){if(!(t.type!=="rule"||!t.parent||t.length<1)){for(var r=t.value,n=t.parent,o=t.column===n.column&&t.line===n.line;n.type!=="rule";)if(n=n.parent,!n)return;if(!(t.props.length===1&&r.charCodeAt(0)!==58&&!qy.get(n))&&!o){qy.set(t,!0);for(var i=[],a=zF(r,i),s=n.props,c=0,l=0;c<a.length;c++)for(var u=0;u<s.length;u++,l++)t.props[l]=i[c]?a[c].replace(/&\f/g,s[u]):s[u]+" "+a[c]}}},XF=function(t){if(t.type==="decl"){var r=t.value;r.charCodeAt(0)===108&&r.charCodeAt(2)===98&&(t.return="",t.value="")}};ZF=function(t,r,n,o){if(t.length>-1&&!t.return)switch(t.type){case Ki:t.return=Jy(t.value,t.length);break;case Rl:return Ho([oa(t,{value:ee(t.value,"@","@"+ne)})],o);case zi:if(t.length)return jd(t.props,function(i){switch(Vd(i,/(::plac\w+|:read-\w+)/)){case":read-only":case":read-write":return Ho([oa(t,{props:[ee(i,/:(read-\w+)/,":"+Ds+"$1")]})],o);case"::placeholder":return Ho([oa(t,{props:[ee(i,/:(plac\w+)/,":"+ne+"input-$1")]}),oa(t,{props:[ee(i,/:(plac\w+)/,":"+Ds+"$1")]}),oa(t,{props:[ee(i,/:(plac\w+)/,At+"input-$1")]})],o)}return""})}},e5=[ZF],Wy=function(t){var r=t.key;if(r==="css"){var n=document.querySelectorAll("style[data-emotion]:not([data-s])");Array.prototype.forEach.call(n,function(y){var E=y.getAttribute("data-emotion");E.indexOf(" ")!==-1&&(document.head.appendChild(y),y.setAttribute("data-s",""))})}var o=t.stylisPlugins||e5,i={},a,s=[];a=t.container||document.head,Array.prototype.forEach.call(document.querySelectorAll('style[data-emotion^="'+r+' "]'),function(y){for(var E=y.getAttribute("data-emotion").split(" "),b=1;b<E.length;b++)i[E[b]]=!0;s.push(y)});var c,l=[KF,XF];{var u,A=[Uy,jy(function(y){u.insert(y)})],m=Vy(l.concat(o,A)),f=function(E){return Ho(Py(E),m)};c=function(E,b,x,B){u=x,f(E?E+"{"+b.styles+"}":b.styles),B&&(g.inserted[b.name]=!0)}}var g={key:r,sheet:new by({key:r,container:a,nonce:t.nonce,speedy:t.speedy,prepend:t.prepend,insertionPoint:t.insertionPoint}),nonce:t.nonce,inserted:i,registered:{},insert:c};return g.sheet.hydrate(s),g}});var Ky=z(Ae=>{"use strict";var it=typeof Symbol=="function"&&Symbol.for,Jd=it?Symbol.for("react.element"):60103,Wd=it?Symbol.for("react.portal"):60106,Yl=it?Symbol.for("react.fragment"):60107,$l=it?Symbol.for("react.strict_mode"):60108,ql=it?Symbol.for("react.profiler"):60114,Jl=it?Symbol.for("react.provider"):60109,Wl=it?Symbol.for("react.context"):60110,zd=it?Symbol.for("react.async_mode"):60111,zl=it?Symbol.for("react.concurrent_mode"):60111,Kl=it?Symbol.for("react.forward_ref"):60112,Xl=it?Symbol.for("react.suspense"):60113,t5=it?Symbol.for("react.suspense_list"):60120,Zl=it?Symbol.for("react.memo"):60115,eu=it?Symbol.for("react.lazy"):60116,r5=it?Symbol.for("react.block"):60121,n5=it?Symbol.for("react.fundamental"):60117,o5=it?Symbol.for("react.responder"):60118,i5=it?Symbol.for("react.scope"):60119;function Kt(e){if(typeof e=="object"&&e!==null){var t=e.$$typeof;switch(t){case Jd:switch(e=e.type,e){case zd:case zl:case Yl:case ql:case $l:case Xl:return e;default:switch(e=e&&e.$$typeof,e){case Wl:case Kl:case eu:case Zl:case Jl:return e;default:return t}}case Wd:return t}}}function zy(e){return Kt(e)===zl}Ae.AsyncMode=zd;Ae.ConcurrentMode=zl;Ae.ContextConsumer=Wl;Ae.ContextProvider=Jl;Ae.Element=Jd;Ae.ForwardRef=Kl;Ae.Fragment=Yl;Ae.Lazy=eu;Ae.Memo=Zl;Ae.Portal=Wd;Ae.Profiler=ql;Ae.StrictMode=$l;Ae.Suspense=Xl;Ae.isAsyncMode=function(e){return zy(e)||Kt(e)===zd};Ae.isConcurrentMode=zy;Ae.isContextConsumer=function(e){return Kt(e)===Wl};Ae.isContextProvider=function(e){return Kt(e)===Jl};Ae.isElement=function(e){return typeof e=="object"&&e!==null&&e.$$typeof===Jd};Ae.isForwardRef=function(e){return Kt(e)===Kl};Ae.isFragment=function(e){return Kt(e)===Yl};Ae.isLazy=function(e){return Kt(e)===eu};Ae.isMemo=function(e){return Kt(e)===Zl};Ae.isPortal=function(e){return Kt(e)===Wd};Ae.isProfiler=function(e){return Kt(e)===ql};Ae.isStrictMode=function(e){return Kt(e)===$l};Ae.isSuspense=function(e){return Kt(e)===Xl};Ae.isValidElementType=function(e){return typeof e=="string"||typeof e=="function"||e===Yl||e===zl||e===ql||e===$l||e===Xl||e===t5||typeof e=="object"&&e!==null&&(e.$$typeof===eu||e.$$typeof===Zl||e.$$typeof===Jl||e.$$typeof===Wl||e.$$typeof===Kl||e.$$typeof===n5||e.$$typeof===o5||e.$$typeof===i5||e.$$typeof===r5)};Ae.typeOf=Kt});var Zy=z((J7,Xy)=>{"use strict";Xy.exports=Ky()});var ax=z((W7,ix)=>{"use strict";var Kd=Zy(),a5={childContextTypes:!0,contextType:!0,contextTypes:!0,defaultProps:!0,displayName:!0,getDefaultProps:!0,getDerivedStateFromError:!0,getDerivedStateFromProps:!0,mixins:!0,propTypes:!0,type:!0},s5={name:!0,length:!0,prototype:!0,caller:!0,callee:!0,arguments:!0,arity:!0},c5={$$typeof:!0,render:!0,defaultProps:!0,displayName:!0,propTypes:!0},nx={$$typeof:!0,compare:!0,defaultProps:!0,displayName:!0,propTypes:!0,type:!0},Xd={};Xd[Kd.ForwardRef]=c5;Xd[Kd.Memo]=nx;function ex(e){return Kd.isMemo(e)?nx:Xd[e.$$typeof]||a5}var l5=Object.defineProperty,u5=Object.getOwnPropertyNames,tx=Object.getOwnPropertySymbols,f5=Object.getOwnPropertyDescriptor,A5=Object.getPrototypeOf,rx=Object.prototype;function ox(e,t,r){if(typeof t!="string"){if(rx){var n=A5(t);n&&n!==rx&&ox(e,n,r)}var o=u5(t);tx&&(o=o.concat(tx(t)));for(var i=ex(e),a=ex(t),s=0;s<o.length;++s){var c=o[s];if(!s5[c]&&!(r&&r[c])&&!(a&&a[c])&&!(i&&i[c])){var l=f5(t,c);try{l5(e,c,l)}catch{}}}}return e}ix.exports=ox});function Vo(e,t,r){var n="";return r.split(" ").forEach(function(o){e[o]!==void 0?t.push(e[o]+";"):o&&(n+=o+" ")}),n}var d5,sa,jo,ca=d(()=>{d5=!0;sa=function(t,r,n){var o=t.key+"-"+r.name;(n===!1||d5===!1)&&t.registered[o]===void 0&&(t.registered[o]=r.styles)},jo=function(t,r,n){sa(t,r,n);var o=t.key+"-"+r.name;if(t.inserted[r.name]===void 0){var i=r;do t.insert(r===i?"."+o:"",i,t.sheet,!0),i=i.next;while(i!==void 0)}}});function sx(e){for(var t=0,r,n=0,o=e.length;o>=4;++n,o-=4)r=e.charCodeAt(n)&255|(e.charCodeAt(++n)&255)<<8|(e.charCodeAt(++n)&255)<<16|(e.charCodeAt(++n)&255)<<24,r=(r&65535)*1540483477+((r>>>16)*59797<<16),r^=r>>>24,t=(r&65535)*1540483477+((r>>>16)*59797<<16)^(t&65535)*1540483477+((t>>>16)*59797<<16);switch(o){case 3:t^=(e.charCodeAt(n+2)&255)<<16;case 2:t^=(e.charCodeAt(n+1)&255)<<8;case 1:t^=e.charCodeAt(n)&255,t=(t&65535)*1540483477+((t>>>16)*59797<<16)}return t^=t>>>13,t=(t&65535)*1540483477+((t>>>16)*59797<<16),((t^t>>>15)>>>0).toString(36)}var cx=d(()=>{});var lx,ux=d(()=>{lx={animationIterationCount:1,aspectRatio:1,borderImageOutset:1,borderImageSlice:1,borderImageWidth:1,boxFlex:1,boxFlexGroup:1,boxOrdinalGroup:1,columnCount:1,columns:1,flex:1,flexGrow:1,flexPositive:1,flexShrink:1,flexNegative:1,flexOrder:1,gridRow:1,gridRowEnd:1,gridRowSpan:1,gridRowStart:1,gridColumn:1,gridColumnEnd:1,gridColumnSpan:1,gridColumnStart:1,msGridRow:1,msGridRowSpan:1,msGridColumn:1,msGridColumnSpan:1,fontWeight:1,lineHeight:1,opacity:1,order:1,orphans:1,scale:1,tabSize:1,widows:1,zIndex:1,zoom:1,WebkitLineClamp:1,fillOpacity:1,floodOpacity:1,stopOpacity:1,strokeDasharray:1,strokeDashoffset:1,strokeMiterlimit:1,strokeOpacity:1,strokeWidth:1}});function Fs(e,t,r){if(r==null)return"";var n=r;if(n.__emotion_styles!==void 0)return n;switch(typeof r){case"boolean":return"";case"object":{var o=r;if(o.anim===1)return on={name:o.name,styles:o.styles,next:on},o.name;var i=r;if(i.styles!==void 0){var a=i.next;if(a!==void 0)for(;a!==void 0;)on={name:a.name,styles:a.styles,next:on},a=a.next;var s=i.styles+";";return s}return C5(e,t,r)}case"function":{if(e!==void 0){var c=on,l=r(e);return on=c,Fs(e,t,l)}break}}var u=r;if(t==null)return u;var A=t[u];return A!==void 0?A:u}function C5(e,t,r){var n="";if(Array.isArray(r))for(var o=0;o<r.length;o++)n+=Fs(e,t,r[o])+";";else for(var i in r){var a=r[i];if(typeof a!="object"){var s=a;t!=null&&t[s]!==void 0?n+=i+"{"+t[s]+"}":fx(s)&&(n+=Zd(i)+":"+Ax(i,s)+";")}else{if(i==="NO_COMPONENT_SELECTOR"&&m5)throw new Error(h5);if(Array.isArray(a)&&typeof a[0]=="string"&&(t==null||t[a[0]]===void 0))for(var c=0;c<a.length;c++)fx(a[c])&&(n+=Zd(i)+":"+Ax(i,a[c])+";");else{var l=Fs(e,t,a);switch(i){case"animation":case"animationName":{n+=Zd(i)+":"+l+";";break}default:n+=i+"{"+l+"}"}}}}return n}function an(e,t,r){if(e.length===1&&typeof e[0]=="object"&&e[0]!==null&&e[0].styles!==void 0)return e[0];var n=!0,o="";on=void 0;var i=e[0];if(i==null||i.raw===void 0)n=!1,o+=Fs(r,t,i);else{var a=i;o+=a[0]}for(var s=1;s<e.length;s++)if(o+=Fs(r,t,e[s]),n){var c=i;o+=c[s]}dx.lastIndex=0;for(var l="",u;(u=dx.exec(o))!==null;)l+="-"+u[1];var A=sx(o)+l;return{name:A,styles:o,next:on}}var m5,p5,g5,mx,fx,Zd,Ax,h5,dx,on,Yo=d(()=>{cx();ux();jl();m5=!1,p5=/[A-Z]|^ms/g,g5=/_EMO_([^_]+?)_([^]*?)_EMO_/g,mx=function(t){return t.charCodeAt(1)===45},fx=function(t){return t!=null&&typeof t!="boolean"},Zd=Vl(function(e){return mx(e)?e:e.replace(p5,"-$&").toLowerCase()}),Ax=function(t,r){switch(t){case"animation":case"animationName":if(typeof r=="string")return r.replace(g5,function(n,o,i){return on={name:o,styles:i,next:on},o})}return lx[t]!==1&&!mx(t)&&typeof r=="number"&&r!==0?r+"px":r},h5="Component selectors can only be used in conjunction with @emotion/babel-plugin, the swc Emotion plugin, or another Emotion-aware compiler transform.";dx=/label:\s*([^\s;{]+)\s*(;|$)/g});var tu,y5,x5,Ps,Os=d(()=>{tu=p(k()),y5=function(t){return t()},x5=tu.useInsertionEffect?tu.useInsertionEffect:!1,Ps=x5||y5});var pr,Gs,px,tm,E5,rm,Us,no,ru,em,gx,b5,I5,hx,nm=d(()=>{pr=p(k()),Gs=p(k());qd();ks();Hl();ca();Yo();Os();px=!1,tm=pr.createContext(typeof HTMLElement<"u"?Wy({key:"css"}):null),E5=tm.Provider,rm=function(){return(0,Gs.useContext)(tm)},Us=function(t){return(0,Gs.forwardRef)(function(r,n){var o=(0,Gs.useContext)(tm);return t(r,o,n)})},no=pr.createContext({}),ru={}.hasOwnProperty,em="__EMOTION_TYPE_PLEASE_DO_NOT_USE__",gx=function(t,r){var n={};for(var o in r)ru.call(r,o)&&(n[o]=r[o]);return n[em]=t,n},b5=function(t){var r=t.cache,n=t.serialized,o=t.isStringTag;return sa(r,n,o),Ps(function(){return jo(r,n,o)}),null},I5=Us(function(e,t,r){var n=e.css;typeof n=="string"&&t.registered[n]!==void 0&&(n=t.registered[n]);var o=e[em],i=[n],a="";typeof e.className=="string"?a=Vo(t.registered,i,e.className):e.className!=null&&(a=e.className+" ");var s=an(i,void 0,pr.useContext(no));a+=t.key+"-"+s.name;var c={};for(var l in e)ru.call(e,l)&&l!=="css"&&l!==em&&!px&&(c[l]=e[l]);return c.className=a,r&&(c.ref=r),pr.createElement(pr.Fragment,null,pr.createElement(b5,{cache:t,serialized:s,isStringTag:typeof o=="string"}),pr.createElement(o,c))}),hx=I5});function yx(){for(var e=arguments.length,t=new Array(e),r=0;r<e;r++)t[r]=arguments[r];return an(t)}function nu(){var e=yx.apply(void 0,arguments),t="animation-"+e.name;return{name:t,styles:"@keyframes "+t+"{"+e.styles+"}",anim:1,toString:function(){return"_EMO_"+this.name+"_"+this.styles+"_EMO_"}}}var la,IY,Cx,Hs=d(()=>{nm();nm();la=p(k());ca();Os();Yo();qd();ks();Hl();IY=p(ax()),Cx=function(t,r){var n=arguments;if(r==null||!ru.call(r,"css"))return la.createElement.apply(void 0,n);var o=n.length,i=new Array(o);i[0]=hx,i[1]=gx(t,r);for(var a=2;a<o;a++)i[a]=n[a];return la.createElement.apply(null,i)};(function(e){var t;t||(t=e.JSX||(e.JSX={}))})(Cx||(Cx={}))});var w5,xx,om=d(()=>{jl();w5=/^((children|dangerouslySetInnerHTML|key|ref|autoFocus|defaultValue|defaultChecked|innerHTML|suppressContentEditableWarning|suppressHydrationWarning|valueLink|abbr|accept|acceptCharset|accessKey|action|allow|allowUserMedia|allowPaymentRequest|allowFullScreen|allowTransparency|alt|async|autoComplete|autoPlay|capture|cellPadding|cellSpacing|challenge|charSet|checked|cite|classID|className|cols|colSpan|content|contentEditable|contextMenu|controls|controlsList|coords|crossOrigin|data|dateTime|decoding|default|defer|dir|disabled|disablePictureInPicture|disableRemotePlayback|download|draggable|encType|enterKeyHint|fetchpriority|fetchPriority|form|formAction|formEncType|formMethod|formNoValidate|formTarget|frameBorder|headers|height|hidden|high|href|hrefLang|htmlFor|httpEquiv|id|inputMode|integrity|is|keyParams|keyType|kind|label|lang|list|loading|loop|low|marginHeight|marginWidth|max|maxLength|media|mediaGroup|method|min|minLength|multiple|muted|name|nonce|noValidate|open|optimum|pattern|placeholder|playsInline|popover|popoverTarget|popoverTargetAction|poster|preload|profile|radioGroup|readOnly|referrerPolicy|rel|required|reversed|role|rows|rowSpan|sandbox|scope|scoped|scrolling|seamless|selected|shape|size|sizes|slot|span|spellCheck|src|srcDoc|srcLang|srcSet|start|step|style|summary|tabIndex|target|title|translate|type|useMap|value|width|wmode|wrap|about|datatype|inlist|prefix|property|resource|typeof|vocab|autoCapitalize|autoCorrect|autoSave|color|incremental|fallback|inert|itemProp|itemScope|itemType|itemID|itemRef|on|option|results|security|unselectable|accentHeight|accumulate|additive|alignmentBaseline|allowReorder|alphabetic|amplitude|arabicForm|ascent|attributeName|attributeType|autoReverse|azimuth|baseFrequency|baselineShift|baseProfile|bbox|begin|bias|by|calcMode|capHeight|clip|clipPathUnits|clipPath|clipRule|colorInterpolation|colorInterpolationFilters|colorProfile|colorRendering|contentScriptType|contentStyleType|cursor|cx|cy|d|decelerate|descent|diffuseConstant|direction|display|divisor|dominantBaseline|dur|dx|dy|edgeMode|elevation|enableBackground|end|exponent|externalResourcesRequired|fill|fillOpacity|fillRule|filter|filterRes|filterUnits|floodColor|floodOpacity|focusable|fontFamily|fontSize|fontSizeAdjust|fontStretch|fontStyle|fontVariant|fontWeight|format|from|fr|fx|fy|g1|g2|glyphName|glyphOrientationHorizontal|glyphOrientationVertical|glyphRef|gradientTransform|gradientUnits|hanging|horizAdvX|horizOriginX|ideographic|imageRendering|in|in2|intercept|k|k1|k2|k3|k4|kernelMatrix|kernelUnitLength|kerning|keyPoints|keySplines|keyTimes|lengthAdjust|letterSpacing|lightingColor|limitingConeAngle|local|markerEnd|markerMid|markerStart|markerHeight|markerUnits|markerWidth|mask|maskContentUnits|maskUnits|mathematical|mode|numOctaves|offset|opacity|operator|order|orient|orientation|origin|overflow|overlinePosition|overlineThickness|panose1|paintOrder|pathLength|patternContentUnits|patternTransform|patternUnits|pointerEvents|points|pointsAtX|pointsAtY|pointsAtZ|preserveAlpha|preserveAspectRatio|primitiveUnits|r|radius|refX|refY|renderingIntent|repeatCount|repeatDur|requiredExtensions|requiredFeatures|restart|result|rotate|rx|ry|scale|seed|shapeRendering|slope|spacing|specularConstant|specularExponent|speed|spreadMethod|startOffset|stdDeviation|stemh|stemv|stitchTiles|stopColor|stopOpacity|strikethroughPosition|strikethroughThickness|string|stroke|strokeDasharray|strokeDashoffset|strokeLinecap|strokeLinejoin|strokeMiterlimit|strokeOpacity|strokeWidth|surfaceScale|systemLanguage|tableValues|targetX|targetY|textAnchor|textDecoration|textRendering|textLength|to|transform|u1|u2|underlinePosition|underlineThickness|unicode|unicodeBidi|unicodeRange|unitsPerEm|vAlphabetic|vHanging|vIdeographic|vMathematical|values|vectorEffect|version|vertAdvY|vertOriginX|vertOriginY|viewBox|viewTarget|visibility|widths|wordSpacing|writingMode|x|xHeight|x1|x2|xChannelSelector|xlinkActuate|xlinkArcrole|xlinkHref|xlinkRole|xlinkShow|xlinkTitle|xlinkType|xmlBase|xmlns|xmlnsXlink|xmlLang|xmlSpace|y|y1|y2|yChannelSelector|z|zoomAndPan|for|class|autofocus)|(([Dd][Aa][Tt][Aa]|[Aa][Rr][Ii][Aa]|x)-.*))$/,xx=Vl(function(e){return w5.test(e)||e.charCodeAt(0)===111&&e.charCodeAt(1)===110&&e.charCodeAt(2)<91})});var oo,S5,B5,v5,Ex,bx,T5,Ix,wx=d(()=>{ks();Hs();Yo();Os();ca();oo=p(k());om();S5=!1,B5=xx,v5=function(t){return t!=="theme"},Ex=function(t){return typeof t=="string"&&t.charCodeAt(0)>96?B5:v5},bx=function(t,r,n){var o;if(r){var i=r.shouldForwardProp;o=t.__emotion_forwardProp&&i?function(a){return t.__emotion_forwardProp(a)&&i(a)}:i}return typeof o!="function"&&n&&(o=t.__emotion_forwardProp),o},T5=function(t){var r=t.cache,n=t.serialized,o=t.isStringTag;return sa(r,n,o),Ps(function(){return jo(r,n,o)}),null},Ix=function e(t,r){var n=t.__emotion_real===t,o=n&&t.__emotion_base||t,i,a;r!==void 0&&(i=r.label,a=r.target);var s=bx(t,r,n),c=s||Ex(o),l=!c("as");return function(){var u=arguments,A=n&&t.__emotion_styles!==void 0?t.__emotion_styles.slice(0):[];if(i!==void 0&&A.push("label:"+i+";"),u[0]==null||u[0].raw===void 0)A.push.apply(A,u);else{var m=u[0];A.push(m[0]);for(var f=u.length,g=1;g<f;g++)A.push(u[g],m[g])}var y=Us(function(E,b,x){var B=l&&E.as||o,I="",w=[],S=E;if(E.theme==null){S={};for(var v in E)S[v]=E[v];S.theme=oo.useContext(no)}typeof E.className=="string"?I=Vo(b.registered,w,E.className):E.className!=null&&(I=E.className+" ");var D=an(A.concat(w),b.registered,S);I+=b.key+"-"+D.name,a!==void 0&&(I+=" "+a);var N=l&&s===void 0?Ex(B):c,L={};for(var P in E)l&&P==="as"||N(P)&&(L[P]=E[P]);return L.className=I,x&&(L.ref=x),oo.createElement(oo.Fragment,null,oo.createElement(T5,{cache:b,serialized:D,isStringTag:typeof B=="string"}),oo.createElement(B,L))});return y.displayName=i!==void 0?i:"Styled("+(typeof o=="string"?o:o.displayName||o.name||"Component")+")",y.defaultProps=t.defaultProps,y.__emotion_real=y,y.__emotion_base=o,y.__emotion_styles=A,y.__emotion_forwardProp=s,Object.defineProperty(y,"toString",{value:function(){return a===void 0&&S5?"NO_COMPONENT_SELECTOR":"."+a}}),y.withComponent=function(E,b){var x=e(E,_s({},r,b,{shouldForwardProp:bx(y,b,!0)}));return x.apply(void 0,A)},y}}});var GY,Q5,ou,Sx=d(()=>{wx();ks();Yo();Os();ca();GY=p(k());om();Q5=["a","abbr","address","area","article","aside","audio","b","base","bdi","bdo","big","blockquote","body","br","button","canvas","caption","cite","code","col","colgroup","data","datalist","dd","del","details","dfn","dialog","div","dl","dt","em","embed","fieldset","figcaption","figure","footer","form","h1","h2","h3","h4","h5","h6","head","header","hgroup","hr","html","i","iframe","img","input","ins","kbd","keygen","label","legend","li","link","main","map","mark","marquee","menu","menuitem","meta","meter","nav","noscript","object","ol","optgroup","option","output","p","param","picture","pre","progress","q","rp","rt","ruby","s","samp","script","section","select","small","source","span","strong","style","sub","summary","sup","table","tbody","td","textarea","tfoot","th","thead","time","title","tr","track","u","ul","var","video","wbr","circle","clipPath","defs","ellipse","foreignObject","g","image","line","linearGradient","mask","path","pattern","polygon","polyline","radialGradient","rect","stop","svg","text","tspan"],ou=Ix.bind(null);Q5.forEach(function(e){ou[e]=ou(e)})});var O=z((VY,Bx)=>{Bx.exports=JBrowseExports["react/jsx-runtime"]});function M5(e,t){return ou(e,t)}function Tx(e,t){Array.isArray(e.__emotion_styles)&&(e.__emotion_styles=t(e.__emotion_styles))}function kn(e){return vx[0]=e,an(vx)}var iu,vx,Vs=d(()=>{"use client";Sx();Yo();Hs();iu=M5;vx=[]});var _5,Qx,Mx=d(()=>{_5={borderRadius:4},Qx=_5});function ua(e=8,t=Ss({spacing:e})){if(e.mui)return e;let r=(...n)=>(n.length===0?[1]:n).map(i=>{let a=t(i);return typeof a=="number"?`${a}px`:a}).join(" ");return r.mui=!0,r}var im=d(()=>{Oo()});function am(e,t){let r=this;if(r.vars){if(!r.colorSchemes?.[e]||typeof r.getColorSchemeSelector!="function")return{};let n=r.getColorSchemeSelector(e);return n==="&"?t:((n.includes("data-")||n.includes("."))&&(n=`*:where(${n.replace(/\s*&$/,"")}) &`),{[n]:t})}return r.palette.mode===e?t:{}}var _x=d(()=>{});function k5(e={},...t){let{breakpoints:r={},palette:n={},spacing:o,shape:i={},...a}=e,s=Es(r),c=ua(o),l=We({breakpoints:s,direction:"ltr",components:{},palette:{mode:"light",...n},spacing:c,shape:{...Qx,...i}},a);return l=Ql(l),l.applyStyles=am,l=t.reduce((u,A)=>We(u,A),l),l.unstable_sxConfig={..._n,...a?.unstable_sxConfig},l.unstable_sx=function(A){return dr({sx:A,theme:this})},l.internal_cache={},l}var $o,kx=d(()=>{Mn();Td();Ml();Mx();im();Hd();Dl();_x();$o=k5});var au=d(()=>{kx()});function D5(e){return Object.keys(e).length===0}function N5(e=null){let t=Dx.useContext(no);return!t||D5(t)?e:t}var Dx,sm,Nx=d(()=>{"use client";Dx=p(k(),1);Vs();sm=N5});var Rx=d(()=>{Nx()});function L5(e=R5){return sm(e)}var R5,cm,lm=d(()=>{"use client";au();Rx();R5=$o();cm=L5});var Lx=d(()=>{lm();lm()});var F5,P5,O5,G5,U5,H5,V5,j5,Y5,$5,q5,J5,W5,E$,Fx=d(()=>{nn();to();F5=j({prop:"flexBasis"}),P5=j({prop:"flexDirection"}),O5=j({prop:"flexWrap"}),G5=j({prop:"justifyContent"}),U5=j({prop:"alignItems"}),H5=j({prop:"alignContent"}),V5=j({prop:"order"}),j5=j({prop:"flex"}),Y5=j({prop:"flexGrow"}),$5=j({prop:"flexShrink"}),q5=j({prop:"alignSelf"}),J5=j({prop:"justifyItems"}),W5=j({prop:"justifySelf"}),E$=_t(F5,P5,O5,G5,U5,H5,V5,j5,Y5,$5,q5,J5,W5)});var Px=d(()=>{Fx()});var z5,K5,X5,Z5,eP,tP,v$,Ox=d(()=>{nn();to();z5=j({prop:"position"}),K5=j({prop:"zIndex",themeKey:"zIndex"}),X5=j({prop:"top"}),Z5=j({prop:"right"}),eP=j({prop:"bottom"}),tP=j({prop:"left"}),v$=_t(z5,K5,X5,Z5,eP,tP)});var Gx=d(()=>{Ox()});var rP,nP,oP,iP,aP,sP,cP,lP,uP,D$,Ux=d(()=>{nn();to();rP=j({prop:"fontFamily",themeKey:"typography"}),nP=j({prop:"fontSize",themeKey:"typography"}),oP=j({prop:"fontStyle",themeKey:"typography"}),iP=j({prop:"fontWeight",themeKey:"typography"}),aP=j({prop:"letterSpacing"}),sP=j({prop:"textTransform"}),cP=j({prop:"lineHeight"}),lP=j({prop:"textAlign"}),uP=j({prop:"typography",cssProperty:!1,themeKey:"typography"}),D$=_t(uP,rP,nP,oP,iP,aP,cP,lP,sP)});var Hx=d(()=>{Ux()});var Vx,fP,AP,js,jx=d(()=>{Vx=e=>e,fP=()=>{let e=Vx;return{configure(t){e=t},generate(t){return e(t)},reset(){e=Vx}}},AP=fP(),js=AP});var um=d(()=>{jx()});function su(e={}){let{themeId:t,defaultTheme:r,defaultClassName:n="MuiBox-root",generateClassName:o}=e,i=iu("div",{shouldForwardProp:s=>s!=="theme"&&s!=="sx"&&s!=="as"})(dr);return Yx.forwardRef(function(c,l){let u=cm(r),{className:A,component:m="div",...f}=c;return(0,$x.jsx)(i,{as:m,ref:l,className:Vi(A,o?o(n):n),theme:t&&u[t]||u,...f})})}var Yx,$x,qx=d(()=>{"use client";Yx=p(k(),1);ml();Vs();Ms();Lx();$x=p(O(),1)});var Jx=d(()=>{qx()});function fa(e,t,r="Mui"){let n=dP[t];return n?`${r}-${n}`:`${js.generate(e)}-${t}`}var dP,fm=d(()=>{um();dP={active:"active",checked:"checked",completed:"completed",disabled:"disabled",error:"error",expanded:"expanded",focused:"focused",focusVisible:"focusVisible",open:"open",readOnly:"readOnly",required:"required",selected:"selected"}});var Am=d(()=>{fm();fm()});function gr(e,t,r="Mui"){let n={};return t.forEach(o=>{n[o]=fa(e,o,r)}),n}var Wx=d(()=>{Am()});var Aa=d(()=>{Wx()});var mP,zx,dm=d(()=>{Aa();mP=gr("MuiBox",["root"]),zx=mP});var sq,Kx=d(()=>{"use client";um();Jx();dm();sq=su({defaultClassName:zx.root,generateClassName:js.generate})});var Xx=d(()=>{Kx();dm()});function Ys(e){let{variants:t,...r}=e,n={variants:t,style:kn(r),isProcessed:!0};return n.style===r||t&&t.forEach(o=>{typeof o.style!="function"&&(o.style=kn(o.style))}),n}var mm=d(()=>{Vs()});function pm(e){return e!=="ownerState"&&e!=="theme"&&e!=="sx"&&e!=="as"}function qo(e,t){return t&&e&&typeof e=="object"&&e.styles&&!e.styles.startsWith("@layer")&&(e.styles=`@layer ${t}{${String(e.styles)}}`),e}function gP(e){return e?(t,r)=>r[e]:null}function hP(e,t,r){e.theme=qi(e.theme)?r:e.theme[t]||e.theme}function cu(e,t,r){let n=typeof t=="function"?t(e):t;if(Array.isArray(n))return n.flatMap(o=>cu(e,o,r));if(Array.isArray(n?.variants)){let o;if(n.isProcessed)o=r?qo(n.style,r):n.style;else{let{variants:i,...a}=n;o=r?qo(kn(a),r):a}return Zx(e,n.variants,[o],r)}return n?.isProcessed?r?qo(kn(n.style),r):n.style:r?qo(kn(n),r):n}function Zx(e,t,r=[],n=void 0){let o;e:for(let i=0;i<t.length;i+=1){let a=t[i];if(typeof a.props=="function"){if(o??={...e,...e.ownerState,ownerState:e.ownerState},!a.props(o))continue}else for(let s in a.props)if(e[s]!==a.props[s]&&e.ownerState?.[s]!==a.props[s])continue e;typeof a.style=="function"?(o??={...e,...e.ownerState,ownerState:e.ownerState},r.push(n?qo(kn(a.style(o)),n):a.style(o))):r.push(n?qo(kn(a.style),n):a.style)}return r}function lu(e={}){let{themeId:t,defaultTheme:r=pP,rootShouldForwardProp:n=pm,slotShouldForwardProp:o=pm}=e;function i(s){hP(s,t,r)}return(s,c={})=>{Tx(s,S=>S.filter(v=>v!==dr));let{name:l,slot:u,skipVariantsResolver:A,skipSx:m,overridesResolver:f=gP(xP(u)),...g}=c,y=l&&l.startsWith("Mui")||u?"components":"custom",E=A!==void 0?A:u&&u!=="Root"&&u!=="root"||!1,b=m||!1,x=pm;u==="Root"||u==="root"?x=n:u?x=o:yP(s)&&(x=void 0);let B=iu(s,{shouldForwardProp:x,label:CP(l,u),...g}),I=S=>{if(S.__emotion_real===S)return S;if(typeof S=="function")return function(D){return cu(D,S,D.theme.modularCssLayers?y:void 0)};if(Nr(S)){let v=Ys(S);return function(N){return v.variants?cu(N,v,N.theme.modularCssLayers?y:void 0):N.theme.modularCssLayers?qo(v.style,y):v.style}}return S},w=(...S)=>{let v=[],D=S.map(I),N=[];if(v.push(i),l&&f&&N.push(function(Q){let G=Q.theme.components?.[l]?.styleOverrides;if(!G)return null;let q={};for(let oe in G)q[oe]=cu(Q,G[oe],Q.theme.modularCssLayers?"theme":void 0);return f(Q,q)}),l&&!E&&N.push(function(Q){let G=Q.theme?.components?.[l]?.variants;return G?Zx(Q,G,[],Q.theme.modularCssLayers?"theme":void 0):null}),b||N.push(dr),Array.isArray(D[0])){let h=D.shift(),Q=new Array(v.length).fill(""),_=new Array(N.length).fill(""),G;G=[...Q,...h,..._],G.raw=[...Q,...h.raw,..._],v.unshift(G)}let L=[...v,...D,...N],P=B(...L);return s.muiName&&(P.muiName=s.muiName),P};return B.withConfig&&(w.withConfig=B.withConfig),w}}function CP(e,t){return void 0}function yP(e){return typeof e=="string"&&e.charCodeAt(0)>96}function xP(e){return e&&e.charAt(0).toLowerCase()+e.slice(1)}var pP,gm=d(()=>{Vs();xd();Mn();au();Ms();mm();pP=$o()});var hm=d(()=>{gm();gm()});function da(e,t,r=!1){let n={...t};for(let o in e)if(Object.prototype.hasOwnProperty.call(e,o)){let i=o;if(i==="components"||i==="slots")n[i]={...e[i],...n[i]};else if(i==="componentsProps"||i==="slotProps"){let a=e[i],s=t[i];if(!s)n[i]=a||{};else if(!a)n[i]=s;else{n[i]={...s};for(let c in a)if(Object.prototype.hasOwnProperty.call(a,c)){let l=c;n[i][l]=da(a[l],s[l],r)}}}else i==="className"&&r&&t.className!==void 0?n.className=Vi(e?.className,t?.className):i==="style"&&r&&t.style?n.style={...e?.style,...t?.style}:n[i]===void 0&&(n[i]=e[i])}return n}var eE=d(()=>{ml()});var tE=d(()=>{eE()});function EP(e,t=Number.MIN_SAFE_INTEGER,r=Number.MAX_SAFE_INTEGER){return Math.max(t,Math.min(e,r))}var Cm,rE=d(()=>{Cm=EP});var nE=d(()=>{rE()});function xm(e,t=0,r=1){return Cm(e,t,r)}function bP(e){e=e.slice(1);let t=new RegExp(`.{1,${e.length>=6?2:1}}`,"g"),r=e.match(t);return r&&r[0].length===1&&(r=r.map(n=>n+n)),r?`rgb${r.length===4?"a":""}(${r.map((n,o)=>o<3?parseInt(n,16):Math.round(parseInt(n,16)/255*1e3)/1e3).join(", ")})`:""}function io(e){if(e.type)return e;if(e.charAt(0)==="#")return io(bP(e));let t=e.indexOf("("),r=e.substring(0,t);if(!["rgb","rgba","hsl","hsla","color"].includes(r))throw new Error(jt(9,e));let n=e.substring(t+1,e.length-1),o;if(r==="color"){if(n=n.split(" "),o=n.shift(),n.length===4&&n[3].charAt(0)==="/"&&(n[3]=n[3].slice(1)),!["srgb","display-p3","a98-rgb","prophoto-rgb","rec-2020"].includes(o))throw new Error(jt(10,o))}else n=n.split(",");return n=n.map(i=>parseFloat(i)),{type:r,values:n,colorSpace:o}}function uu(e){let{type:t,colorSpace:r}=e,{values:n}=e;return t.includes("rgb")?n=n.map((o,i)=>i<3?parseInt(o,10):o):t.includes("hsl")&&(n[1]=`${n[1]}%`,n[2]=`${n[2]}%`),t.includes("color")?n=`${r} ${n.join(" ")}`:n=`${n.join(", ")}`,`${t}(${n})`}function Em(e){e=io(e);let{values:t}=e,r=t[0],n=t[1]/100,o=t[2]/100,i=n*Math.min(o,1-o),a=(l,u=(l+r/30)%12)=>o-i*Math.max(Math.min(u-3,9-u,1),-1),s="rgb",c=[Math.round(a(0)*255),Math.round(a(8)*255),Math.round(a(4)*255)];return e.type==="hsla"&&(s+="a",c.push(t[3])),uu({type:s,values:c})}function ym(e){e=io(e);let t=e.type==="hsl"||e.type==="hsla"?io(Em(e)).values:e.values;return t=t.map(r=>(e.type!=="color"&&(r/=255),r<=.03928?r/12.92:((r+.055)/1.055)**2.4)),Number((.2126*t[0]+.7152*t[1]+.0722*t[2]).toFixed(3))}function oE(e,t){let r=ym(e),n=ym(t);return(Math.max(r,n)+.05)/(Math.min(r,n)+.05)}function bm(e,t){return e=io(e),t=xm(t),(e.type==="rgb"||e.type==="hsl")&&(e.type+="a"),e.type==="color"?e.values[3]=`/${t}`:e.values[3]=t,uu(e)}function ao(e,t,r){try{return bm(e,t)}catch{return e}}function pa(e,t){if(e=io(e),t=xm(t),e.type.includes("hsl"))e.values[2]*=1-t;else if(e.type.includes("rgb")||e.type.includes("color"))for(let r=0;r<3;r+=1)e.values[r]*=1-t;return uu(e)}function ae(e,t,r){try{return pa(e,t)}catch{return e}}function ga(e,t){if(e=io(e),t=xm(t),e.type.includes("hsl"))e.values[2]+=(100-e.values[2])*t;else if(e.type.includes("rgb"))for(let r=0;r<3;r+=1)e.values[r]+=(255-e.values[r])*t;else if(e.type.includes("color"))for(let r=0;r<3;r+=1)e.values[r]+=(1-e.values[r])*t;return uu(e)}function se(e,t,r){try{return ga(e,t)}catch{return e}}function wP(e,t=.15){return ym(e)>.5?pa(e,t):ga(e,t)}function $s(e,t,r){try{return wP(e,t)}catch{return e}}var IP,ma,iE=d(()=>{ji();nE();IP=e=>{let t=io(e);return t.values.slice(0,3).map((r,n)=>t.type.includes("hsl")&&n!==0?`${r}%`:r).join(" ")},ma=(e,t)=>{try{return IP(e)}catch{return e}}});var qs=d(()=>{iE()});var aE,SP,sE=d(()=>{"use client";aE=p(k(),1),SP=p(O(),1)});function TP(e){let{theme:t,name:r,props:n}=e;if(!t||!t.components||!t.components[r])return n;let o=t.components[r];return o.defaultProps?da(o.defaultProps,n,t.components.mergeClassNameAndStyle):!o.styleOverrides&&!o.variants?da(o,n,t.components.mergeClassNameAndStyle):n}function Im({props:e,name:t}){let r=fu.useContext(vP);return TP({props:e,name:t,theme:{components:r}})}var fu,BP,vP,cE=d(()=>{"use client";fu=p(k(),1);tE();BP=p(O(),1),vP=fu.createContext(void 0)});var lE=d(()=>{cE()});function Au(e){let t,r;return function(o){let i=t;return(i===void 0||o.theme!==r)&&(uE.theme=o.theme,i=Ys(e(uE)),t=i,r=o.theme),i}}var uE,fE=d(()=>{mm();uE={theme:void 0}});function du(e=""){function t(...n){if(!n.length)return"";let o=n[0];return typeof o=="string"&&!o.match(/(#|\(|\)|(-?(\d*\.)?\d+)(px|em|%|ex|ch|rem|vw|vh|vmin|vmax|cm|mm|in|pt|pc))|^(-?(\d*\.)?\d+)$|(\d+ \d+ \d+)/)?`, var(--${e?`${e}-`:""}${o}${t(...n.slice(1))})`:`, ${o}`}return(n,...o)=>`var(--${e?`${e}-`:""}${n}${t(...o)})`}var AE=d(()=>{});function Js(e,t){let{prefix:r,shouldSkipGeneratingVar:n}=t||{},o={},i={},a={};return MP(e,(s,c,l)=>{if((typeof c=="string"||typeof c=="number")&&(!n||!n(s,c))){let u=`--${r?`${r}-`:""}${s.join("-")}`,A=_P(s,c);Object.assign(o,{[u]:A}),dE(i,s,`var(${u})`,l),dE(a,s,`var(${u}, ${A})`,l)}},s=>s[0]==="vars"),{css:o,vars:i,varsWithDefaults:a}}var dE,MP,_P,mE=d(()=>{dE=(e,t,r,n=[])=>{let o=e;t.forEach((i,a)=>{a===t.length-1?Array.isArray(o)?o[Number(i)]=r:o&&typeof o=="object"&&(o[i]=r):o&&typeof o=="object"&&(o[i]||(o[i]=n.includes(i)?[]:{}),o=o[i])})},MP=(e,t,r)=>{function n(o,i=[],a=[]){Object.entries(o).forEach(([s,c])=>{(!r||r&&!r([...i,s]))&&c!=null&&(typeof c=="object"&&Object.keys(c).length>0?n(c,[...i,s],Array.isArray(c)?[...a,s]:a):t([...i,s],c,a))})}n(e)},_P=(e,t)=>typeof t=="number"?["lineHeight","fontWeight","opacity","zIndex"].some(n=>e.includes(n))||e[e.length-1].toLowerCase().includes("opacity")?t:`${t}px`:t});function kP(e,t={}){let{getSelector:r=b,disableCssColorScheme:n,colorSchemeSelector:o,enableContrastVars:i}=t,{colorSchemes:a={},components:s,defaultColorScheme:c="light",...l}=e,{vars:u,css:A,varsWithDefaults:m}=Js(l,t),f=m,g={},{[c]:y,...E}=a;if(Object.entries(E||{}).forEach(([I,w])=>{let{vars:S,css:v,varsWithDefaults:D}=Js(w,t);f=We(f,D),g[I]={css:v,vars:S}}),y){let{css:I,vars:w,varsWithDefaults:S}=Js(y,t);f=We(f,S),g[c]={css:I,vars:w}}function b(I,w){let S=o;if(o==="class"&&(S=".%s"),o==="data"&&(S="[data-%s]"),o?.startsWith("data-")&&!o.includes("%s")&&(S=`[${o}="%s"]`),I){if(S==="media")return e.defaultColorScheme===I?":root":{[`@media (prefers-color-scheme: ${a[I]?.palette?.mode||I})`]:{":root":w}};if(S)return e.defaultColorScheme===I?`:root, ${S.replace("%s",String(I))}`:S.replace("%s",String(I))}return":root"}return{vars:f,generateThemeVars:()=>{let I={...u};return Object.entries(g).forEach(([,{vars:w}])=>{I=We(I,w)}),I},generateStyleSheets:()=>{let I=[],w=e.defaultColorScheme||"light";function S(N,L){Object.keys(L).length&&I.push(typeof N=="string"?{[N]:{...L}}:N)}S(r(void 0,{...A}),A);let{[w]:v,...D}=g;if(v){let{css:N}=v,L=a[w]?.palette?.mode,P=!n&&L?{colorScheme:L,...N}:{...N};S(r(w,{...P}),P)}return Object.entries(D).forEach(([N,{css:L}])=>{let P=a[N]?.palette?.mode,h=!n&&P?{colorScheme:P,...L}:{...L};S(r(N,{...h}),h)}),i&&I.push({":root":{"--__l-threshold":"0.7","--__l":"clamp(0, (l / var(--__l-threshold) - 1) * -infinity, 1)","--__a":"clamp(0.87, (l / var(--__l-threshold) - 1) * -infinity, 1)"}}),I}}}var wm,pE=d(()=>{Mn();mE();wm=kP});function Sm(e){return function(r){return e==="media"?`@media (prefers-color-scheme: ${r})`:e?e.startsWith("data-")&&!e.includes("%s")?`[${e}="${r}"] &`:e==="class"?`.${r} &`:e==="data"?`[data-${r}] &`:`${e.replace("%s",r)} &`:"&"}}var gE=d(()=>{});var hE=d(()=>{});var Kq,CE=d(()=>{Aa();Kq=gr("MuiContainer",["root","disableGutters","fixed","maxWidthXs","maxWidthSm","maxWidthMd","maxWidthLg","maxWidthXl"])});var yE=d(()=>{CE()});var xE=d(()=>{});var DP,NP,RP,Ws,rJ,EE=d(()=>{Aa();DP=[0,1,2,3,4,5,6,7,8,9,10],NP=["column-reverse","column","row-reverse","row"],RP=["nowrap","wrap-reverse","wrap"],Ws=["auto","grow",1,2,3,4,5,6,7,8,9,10,11,12],rJ=gr("MuiGrid",["root","container","item",...DP.map(e=>`spacing-xs-${e}`),...NP.map(e=>`direction-xs-${e}`),...RP.map(e=>`wrap-xs-${e}`),...Ws.map(e=>`grid-xs-${e}`),...Ws.map(e=>`grid-sm-${e}`),...Ws.map(e=>`grid-md-${e}`),...Ws.map(e=>`grid-lg-${e}`),...Ws.map(e=>`grid-xl-${e}`)])});var bE=d(()=>{xE();EE()});var IE=d(()=>{});var cJ,wE=d(()=>{Aa();cJ=gr("MuiStack",["root"])});var SE=d(()=>{IE();wE()});var Bm=d(()=>{Pd();Px();Od();Gd();Gx();Ud();Oo();Hx();Xx();hm();im();qs();fE();AE();sE();hE();yE();bE();SE();});var LP,ha,BE=d(()=>{LP={black:"#000",white:"#fff"},ha=LP});var FP,vE,TE=d(()=>{FP={50:"#fafafa",100:"#f5f5f5",200:"#eeeeee",300:"#e0e0e0",400:"#bdbdbd",500:"#9e9e9e",600:"#757575",700:"#616161",800:"#424242",900:"#212121",A100:"#f5f5f5",A200:"#eeeeee",A400:"#bdbdbd",A700:"#616161"},vE=FP});var PP,Jo,QE=d(()=>{PP={50:"#f3e5f5",100:"#e1bee7",200:"#ce93d8",300:"#ba68c8",400:"#ab47bc",500:"#9c27b0",600:"#8e24aa",700:"#7b1fa2",800:"#6a1b9a",900:"#4a148c",A100:"#ea80fc",A200:"#e040fb",A400:"#d500f9",A700:"#aa00ff"},Jo=PP});var OP,Rr,vm=d(()=>{OP={50:"#ffebee",100:"#ffcdd2",200:"#ef9a9a",300:"#e57373",400:"#ef5350",500:"#f44336",600:"#e53935",700:"#d32f2f",800:"#c62828",900:"#b71c1c",A100:"#ff8a80",A200:"#ff5252",A400:"#ff1744",A700:"#d50000"},Rr=OP});var GP,Dn,Tm=d(()=>{GP={50:"#fff3e0",100:"#ffe0b2",200:"#ffcc80",300:"#ffb74d",400:"#ffa726",500:"#ff9800",600:"#fb8c00",700:"#f57c00",800:"#ef6c00",900:"#e65100",A100:"#ffd180",A200:"#ffab40",A400:"#ff9100",A700:"#ff6d00"},Dn=GP});var UP,sn,Qm=d(()=>{UP={50:"#e3f2fd",100:"#bbdefb",200:"#90caf9",300:"#64b5f6",400:"#42a5f5",500:"#2196f3",600:"#1e88e5",700:"#1976d2",800:"#1565c0",900:"#0d47a1",A100:"#82b1ff",A200:"#448aff",A400:"#2979ff",A700:"#2962ff"},sn=UP});var HP,Wo,ME=d(()=>{HP={50:"#e1f5fe",100:"#b3e5fc",200:"#81d4fa",300:"#4fc3f7",400:"#29b6f6",500:"#03a9f4",600:"#039be5",700:"#0288d1",800:"#0277bd",900:"#01579b",A100:"#80d8ff",A200:"#40c4ff",A400:"#00b0ff",A700:"#0091ea"},Wo=HP});var VP,cn,Mm=d(()=>{VP={50:"#e8f5e9",100:"#c8e6c9",200:"#a5d6a7",300:"#81c784",400:"#66bb6a",500:"#4caf50",600:"#43a047",700:"#388e3c",800:"#2e7d32",900:"#1b5e20",A100:"#b9f6ca",A200:"#69f0ae",A400:"#00e676",A700:"#00c853"},cn=VP});function DE(){return{text:{primary:"rgba(0, 0, 0, 0.87)",secondary:"rgba(0, 0, 0, 0.6)",disabled:"rgba(0, 0, 0, 0.38)"},divider:"rgba(0, 0, 0, 0.12)",background:{paper:ha.white,default:ha.white},action:{active:"rgba(0, 0, 0, 0.54)",hover:"rgba(0, 0, 0, 0.04)",hoverOpacity:.04,selected:"rgba(0, 0, 0, 0.08)",selectedOpacity:.08,disabled:"rgba(0, 0, 0, 0.26)",disabledBackground:"rgba(0, 0, 0, 0.12)",disabledOpacity:.38,focus:"rgba(0, 0, 0, 0.12)",focusOpacity:.12,activatedOpacity:.12}}}function NE(){return{text:{primary:ha.white,secondary:"rgba(255, 255, 255, 0.7)",disabled:"rgba(255, 255, 255, 0.5)",icon:"rgba(255, 255, 255, 0.5)"},divider:"rgba(255, 255, 255, 0.12)",background:{paper:"#121212",default:"#121212"},action:{active:ha.white,hover:"rgba(255, 255, 255, 0.08)",hoverOpacity:.08,selected:"rgba(255, 255, 255, 0.16)",selectedOpacity:.16,disabled:"rgba(255, 255, 255, 0.3)",disabledBackground:"rgba(255, 255, 255, 0.12)",disabledOpacity:.38,focus:"rgba(255, 255, 255, 0.12)",focusOpacity:.12,activatedOpacity:.24}}}function _E(e,t,r,n){let o=n.light||n,i=n.dark||n*1.5;e[t]||(e.hasOwnProperty(r)?e[t]=e[r]:t==="light"?e.light=ga(e.main,o):t==="dark"&&(e.dark=pa(e.main,i)))}function kE(e,t,r,n,o){let i=o.light||o,a=o.dark||o*1.5;t[r]||(t.hasOwnProperty(n)?t[r]=t[n]:r==="light"?t.light=`color-mix(in ${e}, ${t.main}, #fff ${(i*100).toFixed(0)}%)`:r==="dark"&&(t.dark=`color-mix(in ${e}, ${t.main}, #000 ${(a*100).toFixed(0)}%)`))}function jP(e="light"){return e==="dark"?{main:sn[200],light:sn[50],dark:sn[400]}:{main:sn[700],light:sn[400],dark:sn[800]}}function YP(e="light"){return e==="dark"?{main:Jo[200],light:Jo[50],dark:Jo[400]}:{main:Jo[500],light:Jo[300],dark:Jo[700]}}function $P(e="light"){return e==="dark"?{main:Rr[500],light:Rr[300],dark:Rr[700]}:{main:Rr[700],light:Rr[400],dark:Rr[800]}}function qP(e="light"){return e==="dark"?{main:Wo[400],light:Wo[300],dark:Wo[700]}:{main:Wo[700],light:Wo[500],dark:Wo[900]}}function JP(e="light"){return e==="dark"?{main:cn[400],light:cn[300],dark:cn[700]}:{main:cn[800],light:cn[500],dark:cn[900]}}function WP(e="light"){return e==="dark"?{main:Dn[400],light:Dn[300],dark:Dn[700]}:{main:"#ed6c02",light:Dn[500],dark:Dn[900]}}function zP(e){return`oklch(from ${e} var(--__l) 0 h / var(--__a))`}function zo(e){let{mode:t="light",contrastThreshold:r=3,tonalOffset:n=.2,colorSpace:o,...i}=e,a=e.primary||jP(t),s=e.secondary||YP(t),c=e.error||$P(t),l=e.info||qP(t),u=e.success||JP(t),A=e.warning||WP(t);function m(E){return o?zP(E):oE(E,mu.text.primary)>=r?mu.text.primary:_m.text.primary}let f=({color:E,name:b,mainShade:x=500,lightShade:B=300,darkShade:I=700})=>{if(E={...E},!E.main&&E[x]&&(E.main=E[x]),!E.hasOwnProperty("main"))throw new Error(jt(11,b?` (${b})`:"",x));if(typeof E.main!="string")throw new Error(jt(12,b?` (${b})`:"",JSON.stringify(E.main)));return o?(kE(o,E,"light",B,n),kE(o,E,"dark",I,n)):(_E(E,"light",B,n),_E(E,"dark",I,n)),E.contrastText||(E.contrastText=m(E.main)),E},g;return t==="light"?g=DE():t==="dark"&&(g=NE()),We({common:{...ha},mode:t,primary:f({color:a,name:"primary"}),secondary:f({color:s,name:"secondary",mainShade:"A400",lightShade:"A200",darkShade:"A700"}),error:f({color:c,name:"error"}),warning:f({color:A,name:"warning"}),info:f({color:l,name:"info"}),success:f({color:u,name:"success"}),grey:vE,contrastThreshold:r,getContrastText:m,augmentColor:f,tonalOffset:n,...g},i)}var _m,mu,zs=d(()=>{ji();Mn();qs();BE();TE();QE();vm();Tm();Qm();ME();Mm();_m=DE();mu=NE()});function pu(e){let t={};return Object.entries(e).forEach(n=>{let[o,i]=n;typeof i=="object"&&(t[o]=`${i.fontStyle?`${i.fontStyle} `:""}${i.fontVariant?`${i.fontVariant} `:""}${i.fontWeight?`${i.fontWeight} `:""}${i.fontStretch?`${i.fontStretch} `:""}${i.fontSize||""}${i.lineHeight?`/${i.lineHeight} `:""}${i.fontFamily||""}`)}),t}var RE=d(()=>{});var LE=d(()=>{pE();RE();gE()});function km(e,t){return{toolbar:{minHeight:56,[e.up("xs")]:{"@media (orientation: landscape)":{minHeight:48}},[e.up("sm")]:{minHeight:64}},...t}}var FE=d(()=>{});function KP(e){return Math.round(e*1e5)/1e5}function Dm(e,t){let{fontFamily:r=OE,fontSize:n=14,fontWeightLight:o=300,fontWeightRegular:i=400,fontWeightMedium:a=500,fontWeightBold:s=700,htmlFontSize:c=16,allVariants:l,pxToRem:u,...A}=typeof t=="function"?t(e):t,m=n/14,f=u||(E=>`${E/c*m}rem`),g=(E,b,x,B,I)=>({fontFamily:r,fontWeight:E,fontSize:f(b),lineHeight:x,...r===OE?{letterSpacing:`${KP(B/b)}em`}:{},...I,...l}),y={h1:g(o,96,1.167,-1.5),h2:g(o,60,1.2,-.5),h3:g(i,48,1.167,0),h4:g(i,34,1.235,.25),h5:g(i,24,1.334,0),h6:g(a,20,1.6,.15),subtitle1:g(i,16,1.75,.15),subtitle2:g(a,14,1.57,.1),body1:g(i,16,1.5,.15),body2:g(i,14,1.43,.15),button:g(a,14,1.75,.4,PE),caption:g(i,12,1.66,.4),overline:g(i,12,2.66,1,PE),inherit:{fontFamily:"inherit",fontWeight:"inherit",fontSize:"inherit",lineHeight:"inherit",letterSpacing:"inherit"}};return We({htmlFontSize:c,pxToRem:f,fontFamily:r,fontSize:n,fontWeightLight:o,fontWeightRegular:i,fontWeightMedium:a,fontWeightBold:s,...y},A,{clone:!1})}var PE,OE,GE=d(()=>{Mn();PE={textTransform:"uppercase"},OE='"Roboto", "Helvetica", "Arial", sans-serif'});function De(...e){return[`${e[0]}px ${e[1]}px ${e[2]}px ${e[3]}px rgba(0,0,0,${.2})`,`${e[4]}px ${e[5]}px ${e[6]}px ${e[7]}px rgba(0,0,0,${.14})`,`${e[8]}px ${e[9]}px ${e[10]}px ${e[11]}px rgba(0,0,0,${.12})`].join(",")}var XP,UE,HE=d(()=>{XP=["none",De(0,2,1,-1,0,1,1,0,0,1,3,0),De(0,3,1,-2,0,2,2,0,0,1,5,0),De(0,3,3,-2,0,3,4,0,0,1,8,0),De(0,2,4,-1,0,4,5,0,0,1,10,0),De(0,3,5,-1,0,5,8,0,0,1,14,0),De(0,3,5,-1,0,6,10,0,0,1,18,0),De(0,4,5,-2,0,7,10,1,0,2,16,1),De(0,5,5,-3,0,8,10,1,0,3,14,2),De(0,5,6,-3,0,9,12,1,0,3,16,2),De(0,6,6,-3,0,10,14,1,0,4,18,3),De(0,6,7,-4,0,11,15,1,0,4,20,3),De(0,7,8,-4,0,12,17,2,0,5,22,4),De(0,7,8,-4,0,13,19,2,0,5,24,4),De(0,7,9,-4,0,14,21,2,0,5,26,4),De(0,8,9,-5,0,15,22,2,0,6,28,5),De(0,8,10,-5,0,16,24,2,0,6,30,5),De(0,8,11,-5,0,17,26,2,0,6,32,5),De(0,9,11,-5,0,18,28,2,0,7,34,6),De(0,9,12,-6,0,19,29,2,0,7,36,6),De(0,10,13,-6,0,20,31,3,0,8,38,7),De(0,10,13,-6,0,21,33,3,0,8,40,7),De(0,10,14,-6,0,22,35,3,0,8,42,7),De(0,11,14,-7,0,23,36,3,0,9,44,8),De(0,11,15,-7,0,24,38,3,0,9,46,8)],UE=XP});function VE(e){return`${Math.round(e)}ms`}function n3(e){if(!e)return 0;let t=e/36;return Math.min(Math.round((4+15*t**.25+t/5)*10),3e3)}function Nm(e){let t={...e};delete t.reducedMotion;let r={...t3,...t.easing},n={...r3,...t.duration},o=(a=ZP,s=e3)=>{let{duration:c=n.standard,easing:l=r.easeInOut,delay:u=0,...A}=s;return(Array.isArray(a)?a:[a]).map(m=>`${m} ${typeof c=="string"?c:VE(c)} ${l} ${typeof u=="string"?u:VE(u)}`).join(",")},i=t.create??o;return{getAutoHeightDuration:n3,create:i,...t,easing:r,duration:n}}var ZP,e3,t3,r3,jE=d(()=>{ZP=["all"],e3={},t3={easeInOut:"cubic-bezier(0.4, 0, 0.2, 1)",easeOut:"cubic-bezier(0.0, 0, 0.2, 1)",easeIn:"cubic-bezier(0.4, 0, 1, 1)",sharp:"cubic-bezier(0.4, 0, 0.6, 1)"},r3={shortest:150,shorter:200,short:250,standard:300,complex:375,enteringScreen:225,leavingScreen:195}});function Rm(e=o3){return{reducedMotion:"never",...e}}var o3,YE=d(()=>{o3={}});var i3,$E,qE=d(()=>{i3={mobileStepper:1e3,fab:1050,speedDial:1050,appBar:1100,drawer:1200,modal:1300,snackbar:1400,tooltip:1500},$E=i3});function a3(e){return Nr(e)||typeof e>"u"||typeof e=="string"||typeof e=="boolean"||typeof e=="number"||Array.isArray(e)}function gu(e={}){let t={...e};function r(n){let o=Object.entries(n);for(let i=0;i<o.length;i++){let[a,s]=o[i];!a3(s)||a.startsWith("unstable_")||a.startsWith("internal_")?delete n[a]:Nr(s)&&(n[a]={...s},r(n[a]))}}return r(t),`import { unstable_createBreakpoints as createBreakpoints, createTransitions } from '@mui/material/styles';
+
+const theme = ${JSON.stringify(t,null,2)};
+
+theme.breakpoints = createBreakpoints(theme.breakpoints || {});
+theme.motion = { reducedMotion: 'never', ...theme.motion };
+theme.transitions = createTransitions(theme.transitions || {});
+
+export default theme;`}var Lm=d(()=>{Mn()});function JE(e){return typeof e=="number"?`${(e*100).toFixed(0)}%`:`calc((${e}) * 100%)`}function c3(e){Object.assign(e,{alpha(t,r){let n=this||e;return n.colorSpace?`oklch(from ${t} l c h / ${typeof r=="string"?`calc(${r})`:r})`:n.vars?`rgba(${t.replace(/var\(--([^,\s)]+)(?:,[^)]+)?\)+/g,"var(--$1Channel)")} / ${typeof r=="string"?`calc(${r})`:r})`:bm(t,s3(r))},lighten(t,r){let n=this||e;return n.colorSpace?`color-mix(in ${n.colorSpace}, ${t}, #fff ${JE(r)})`:ga(t,r)},darken(t,r){let n=this||e;return n.colorSpace?`color-mix(in ${n.colorSpace}, ${t}, #000 ${JE(r)})`:pa(t,r)}})}function l3(e={},...t){let{breakpoints:r,mixins:n={},spacing:o,palette:i={},motion:a={},transitions:s={},typography:c={},shape:l,colorSpace:u,...A}=e;if(e.vars&&e.generateThemeVars===void 0)throw new Error(jt(22));let m=zo({...i,colorSpace:u}),f=$o(e),g=We(f,{mixins:km(f.breakpoints,n),palette:m,shadows:UE.slice(),typography:Dm(m,c),motion:Rm(a),transitions:Nm(s),zIndex:{...$E}});return g=We(g,A),g=t.reduce((y,E)=>We(y,E),g),delete g.transitions.reducedMotion,g.unstable_sxConfig={..._n,...A?.unstable_sxConfig},g.unstable_sx=function(E){return dr({sx:E,theme:this})},g.toRuntimeSource=gu,c3(g),g}var s3,Ks,Fm=d(()=>{ji();Mn();Ms();au();qs();FE();zs();GE();HE();jE();YE();qE();Lm();s3=e=>{if(!Number.isNaN(+e))return+e;let t=e.match(/\d*\.?\d+/g);if(!t)return 0;let r=0;for(let n=0;n<t.length;n+=1)r+=+t[n];return r};Ks=l3});function Pm(e){let t;return e<1?t=5.11916*e**2:t=4.5*Math.log(e+1)+2,Math.round(t*10)/1e3}var WE=d(()=>{});function Om(e){return{inputPlaceholder:e==="dark"?.5:.42,inputUnderline:e==="dark"?.7:.42,switchTrackDisabled:e==="dark"?.2:.12,switchTrack:e==="dark"?.3:.38}}function Gm(e){return e==="dark"?u3:[]}function Um(e){let{palette:t={mode:"light"},opacity:r,overlays:n,colorSpace:o,...i}=e,a=zo({...t,colorSpace:o});return{palette:a,opacity:{...Om(a.mode),...r},overlays:n||Gm(a.mode),...i}}var u3,zE=d(()=>{zs();WE();u3=[...Array(25)].map((e,t)=>{if(t===0)return"none";let r=Pm(t);return`linear-gradient(rgba(255 255 255 / ${r}), rgba(255 255 255 / ${r}))`})});function Hm(e){return e[0]==="motion"||!!e[0].match(/(cssVarPrefix|colorSchemeSelector|modularCssLayers|rootSelector|typography|mixins|breakpoints|direction|transitions)/)||!!e[0].match(/sxConfig$/)||e[0]==="palette"&&!!e[1]?.match(/(mode|contrastThreshold|tonalOffset)/)}var KE=d(()=>{});var f3,XE,ZE=d(()=>{f3=e=>[...[...Array(25)].map((t,r)=>`--${e?`${e}-`:""}overlays-${r}`),`--${e?`${e}-`:""}palette-AppBar-darkBg`,`--${e?`${e}-`:""}palette-AppBar-darkColor`],XE=f3});var eb,tb=d(()=>{ZE();eb=e=>(t,r)=>{let n=e.rootSelector||":root",o=e.colorSchemeSelector,i=o;if(o==="class"&&(i=".%s"),o==="data"&&(i="[data-%s]"),o?.startsWith("data-")&&!o.includes("%s")&&(i=`[${o}="%s"]`),e.defaultColorScheme===t){if(t==="dark"){let a={};return XE(e.cssVarPrefix).forEach(s=>{a[s]=r[s],delete r[s]}),i==="media"?{[n]:r,"@media (prefers-color-scheme: dark)":{[n]:a}}:i?{[i.replace("%s",t)]:a,[`${n}, ${i.replace("%s",t)}`]:r}:{[n]:{...r,...a}}}if(i&&i!=="media")return`${n}, ${i.replace("%s",String(t))}`}else if(t){if(i==="media")return{[`@media (prefers-color-scheme: ${String(t)})`]:{[n]:r}};if(i)return i.replace("%s",String(t))}return n}});function A3(e,t){t.forEach(r=>{e[r]||(e[r]={})})}function M(e,t,r){!e[t]&&r&&(e[t]=r)}function Xs(e){return typeof e!="string"||!e.startsWith("hsl")?e:Em(e)}function Nn(e,t){`${t}Channel`in e||(e[`${t}Channel`]=ma(Xs(e[t]),`MUI: Can't create \`palette.${t}Channel\` because \`palette.${t}\` is not one of these formats: #nnn, #nnnnnn, rgb(), rgba(), hsl(), hsla(), color().
+To suppress this warning, you need to explicitly provide the \`palette.${t}Channel\` as a string (in rgb format, for example "12 12 12") or undefined if you want to remove the channel token.`))}function d3(e){return typeof e=="number"?`${e}px`:typeof e=="string"||typeof e=="function"||Array.isArray(e)?e:"8px"}function Vm(e,t,r,n,o){if(!r)return;r=r===!0?{}:r;let i=o==="dark"?"dark":"light";if(!n){t[o]=Um({...r,palette:{mode:i,...r?.palette},colorSpace:e});return}let{palette:a,...s}=Ks({...n,palette:{mode:i,...r?.palette},colorSpace:e});return t[o]={...r,palette:a,opacity:{...Om(i),...r?.opacity},overlays:r?.overlays||Gm(i)},s}function jm(e={},...t){let{colorSchemes:r={light:!0},defaultColorScheme:n,disableCssColorScheme:o=!1,cssVarPrefix:i="mui",nativeColor:a=!1,shouldSkipGeneratingVar:s=Hm,colorSchemeSelector:c=r.light&&r.dark?"media":void 0,rootSelector:l=":root",...u}=e,A=Object.keys(r)[0],m=n||(r.light&&A!=="light"?"light":A),f=m3(i),{[m]:g,light:y,dark:E,...b}=r,x={...b},B=g;if((m==="dark"&&!("dark"in r)||m==="light"&&!("light"in r))&&(B=!0),!B)throw new Error(jt(21,m));let I;a&&(I="oklch");let w=Vm(I,x,B,u,m);y&&!x.light&&Vm(I,x,y,void 0,"light"),E&&!x.dark&&Vm(I,x,E,void 0,"dark");let S={defaultColorScheme:m,...w,cssVarPrefix:i,colorSchemeSelector:c,rootSelector:l,getCssVar:f,colorSchemes:x,font:{...pu(w.typography),...w.font},spacing:d3(u.spacing)};Object.keys(S.colorSchemes).forEach(P=>{let h=S.colorSchemes[P].palette,Q=G=>{let q=G.split("-"),oe=q[1],tt=q[2];return f(G,h[oe][tt])};h.mode==="light"&&(M(h.common,"background","#fff"),M(h.common,"onBackground","#000")),h.mode==="dark"&&(M(h.common,"background","#000"),M(h.common,"onBackground","#fff"));function _(G,q,oe){if(I){let tt;return G===ao&&(tt=`transparent ${((1-oe)*100).toFixed(0)}%`),G===ae&&(tt=`#000 ${(oe*100).toFixed(0)}%`),G===se&&(tt=`#fff ${(oe*100).toFixed(0)}%`),`color-mix(in ${I}, ${q}, ${tt})`}return G(q,oe)}if(A3(h,["Alert","AppBar","Avatar","Button","Chip","FilledInput","LinearProgress","Skeleton","Slider","SnackbarContent","SpeedDialAction","StepConnector","StepContent","Switch","TableCell","Tooltip"]),h.mode==="light"){M(h.Alert,"errorColor",_(ae,a?f("palette-error-light"):h.error.light,.6)),M(h.Alert,"infoColor",_(ae,a?f("palette-info-light"):h.info.light,.6)),M(h.Alert,"successColor",_(ae,a?f("palette-success-light"):h.success.light,.6)),M(h.Alert,"warningColor",_(ae,a?f("palette-warning-light"):h.warning.light,.6)),M(h.Alert,"errorFilledBg",Q("palette-error-main")),M(h.Alert,"infoFilledBg",Q("palette-info-main")),M(h.Alert,"successFilledBg",Q("palette-success-main")),M(h.Alert,"warningFilledBg",Q("palette-warning-main")),M(h.Alert,"errorFilledColor",ln(()=>h.getContrastText(h.error.main))),M(h.Alert,"infoFilledColor",ln(()=>h.getContrastText(h.info.main))),M(h.Alert,"successFilledColor",ln(()=>h.getContrastText(h.success.main))),M(h.Alert,"warningFilledColor",ln(()=>h.getContrastText(h.warning.main))),M(h.Alert,"errorStandardBg",_(se,a?f("palette-error-light"):h.error.light,.9)),M(h.Alert,"infoStandardBg",_(se,a?f("palette-info-light"):h.info.light,.9)),M(h.Alert,"successStandardBg",_(se,a?f("palette-success-light"):h.success.light,.9)),M(h.Alert,"warningStandardBg",_(se,a?f("palette-warning-light"):h.warning.light,.9)),M(h.Alert,"errorIconColor",Q("palette-error-main")),M(h.Alert,"infoIconColor",Q("palette-info-main")),M(h.Alert,"successIconColor",Q("palette-success-main")),M(h.Alert,"warningIconColor",Q("palette-warning-main")),M(h.AppBar,"defaultBg",Q("palette-grey-100")),M(h.Avatar,"defaultBg",Q("palette-grey-400")),M(h.Button,"inheritContainedBg",Q("palette-grey-300")),M(h.Button,"inheritContainedHoverBg",Q("palette-grey-A100")),M(h.Chip,"defaultBorder",Q("palette-grey-400")),M(h.Chip,"defaultAvatarColor",Q("palette-grey-700")),M(h.Chip,"defaultIconColor",Q("palette-grey-700")),M(h.FilledInput,"bg","rgba(0, 0, 0, 0.06)"),M(h.FilledInput,"hoverBg","rgba(0, 0, 0, 0.09)"),M(h.FilledInput,"disabledBg","rgba(0, 0, 0, 0.12)"),M(h.LinearProgress,"primaryBg",_(se,a?f("palette-primary-main"):h.primary.main,.62)),M(h.LinearProgress,"secondaryBg",_(se,a?f("palette-secondary-main"):h.secondary.main,.62)),M(h.LinearProgress,"errorBg",_(se,a?f("palette-error-main"):h.error.main,.62)),M(h.LinearProgress,"infoBg",_(se,a?f("palette-info-main"):h.info.main,.62)),M(h.LinearProgress,"successBg",_(se,a?f("palette-success-main"):h.success.main,.62)),M(h.LinearProgress,"warningBg",_(se,a?f("palette-warning-light"):h.warning.main,.62)),M(h.Skeleton,"bg",I?_(ao,a?f("palette-text-primary"):h.text.primary,.11):`rgba(${Q("palette-text-primaryChannel")} / 0.11)`),M(h.Slider,"primaryTrack",_(se,a?f("palette-primary-main"):h.primary.main,.62)),M(h.Slider,"secondaryTrack",_(se,a?f("palette-secondary-main"):h.secondary.main,.62)),M(h.Slider,"errorTrack",_(se,a?f("palette-error-main"):h.error.main,.62)),M(h.Slider,"infoTrack",_(se,a?f("palette-info-main"):h.info.main,.62)),M(h.Slider,"successTrack",_(se,a?f("palette-success-main"):h.success.main,.62)),M(h.Slider,"warningTrack",_(se,a?f("palette-warning-main"):h.warning.main,.62));let G=I?_(ae,a?f("palette-background-default"):h.background.default,.6825):$s(h.background.default,.8);M(h.SnackbarContent,"bg",G),M(h.SnackbarContent,"color",ln(()=>I?mu.text.primary:h.getContrastText(G))),M(h.SpeedDialAction,"fabHoverBg",$s(h.background.paper,.15)),M(h.StepConnector,"border",Q("palette-grey-400")),M(h.StepContent,"border",Q("palette-grey-400")),M(h.Switch,"defaultColor",Q("palette-common-white")),M(h.Switch,"defaultDisabledColor",Q("palette-grey-100")),M(h.Switch,"primaryDisabledColor",_(se,a?f("palette-primary-main"):h.primary.main,.62)),M(h.Switch,"secondaryDisabledColor",_(se,a?f("palette-secondary-main"):h.secondary.main,.62)),M(h.Switch,"errorDisabledColor",_(se,a?f("palette-error-main"):h.error.main,.62)),M(h.Switch,"infoDisabledColor",_(se,a?f("palette-info-main"):h.info.main,.62)),M(h.Switch,"successDisabledColor",_(se,a?f("palette-success-main"):h.success.main,.62)),M(h.Switch,"warningDisabledColor",_(se,a?f("palette-warning-main"):h.warning.main,.62)),M(h.TableCell,"border",_(se,ao(a?f("palette-divider"):h.divider,1),.88)),M(h.Tooltip,"bg",_(ao,a?f("palette-grey-700"):h.grey[700],.92))}if(h.mode==="dark"){M(h.Alert,"errorColor",_(se,a?f("palette-error-light"):h.error.light,.6)),M(h.Alert,"infoColor",_(se,a?f("palette-info-light"):h.info.light,.6)),M(h.Alert,"successColor",_(se,a?f("palette-success-light"):h.success.light,.6)),M(h.Alert,"warningColor",_(se,a?f("palette-warning-light"):h.warning.light,.6)),M(h.Alert,"errorFilledBg",Q("palette-error-dark")),M(h.Alert,"infoFilledBg",Q("palette-info-dark")),M(h.Alert,"successFilledBg",Q("palette-success-dark")),M(h.Alert,"warningFilledBg",Q("palette-warning-dark")),M(h.Alert,"errorFilledColor",ln(()=>h.getContrastText(h.error.dark))),M(h.Alert,"infoFilledColor",ln(()=>h.getContrastText(h.info.dark))),M(h.Alert,"successFilledColor",ln(()=>h.getContrastText(h.success.dark))),M(h.Alert,"warningFilledColor",ln(()=>h.getContrastText(h.warning.dark))),M(h.Alert,"errorStandardBg",_(ae,a?f("palette-error-light"):h.error.light,.9)),M(h.Alert,"infoStandardBg",_(ae,a?f("palette-info-light"):h.info.light,.9)),M(h.Alert,"successStandardBg",_(ae,a?f("palette-success-light"):h.success.light,.9)),M(h.Alert,"warningStandardBg",_(ae,a?f("palette-warning-light"):h.warning.light,.9)),M(h.Alert,"errorIconColor",Q("palette-error-main")),M(h.Alert,"infoIconColor",Q("palette-info-main")),M(h.Alert,"successIconColor",Q("palette-success-main")),M(h.Alert,"warningIconColor",Q("palette-warning-main")),M(h.AppBar,"defaultBg",Q("palette-grey-900")),M(h.AppBar,"darkBg",Q("palette-background-paper")),M(h.AppBar,"darkColor",Q("palette-text-primary")),M(h.Avatar,"defaultBg",Q("palette-grey-600")),M(h.Button,"inheritContainedBg",Q("palette-grey-800")),M(h.Button,"inheritContainedHoverBg",Q("palette-grey-700")),M(h.Chip,"defaultBorder",Q("palette-grey-700")),M(h.Chip,"defaultAvatarColor",Q("palette-grey-300")),M(h.Chip,"defaultIconColor",Q("palette-grey-300")),M(h.FilledInput,"bg","rgba(255, 255, 255, 0.09)"),M(h.FilledInput,"hoverBg","rgba(255, 255, 255, 0.13)"),M(h.FilledInput,"disabledBg","rgba(255, 255, 255, 0.12)"),M(h.LinearProgress,"primaryBg",_(ae,a?f("palette-primary-main"):h.primary.main,.5)),M(h.LinearProgress,"secondaryBg",_(ae,a?f("palette-secondary-main"):h.secondary.main,.5)),M(h.LinearProgress,"errorBg",_(ae,a?f("palette-error-main"):h.error.main,.5)),M(h.LinearProgress,"infoBg",_(ae,a?f("palette-info-main"):h.info.main,.5)),M(h.LinearProgress,"successBg",_(ae,a?f("palette-success-main"):h.success.main,.5)),M(h.LinearProgress,"warningBg",_(ae,a?f("palette-warning-main"):h.warning.main,.5)),M(h.Skeleton,"bg",I?_(ao,a?f("palette-text-primary"):h.text.primary,.13):`rgba(${Q("palette-text-primaryChannel")} / 0.13)`),M(h.Slider,"primaryTrack",_(ae,a?f("palette-primary-main"):h.primary.main,.5)),M(h.Slider,"secondaryTrack",_(ae,a?f("palette-secondary-main"):h.secondary.main,.5)),M(h.Slider,"errorTrack",_(ae,a?f("palette-error-main"):h.error.main,.5)),M(h.Slider,"infoTrack",_(ae,a?f("palette-info-main"):h.info.main,.5)),M(h.Slider,"successTrack",_(ae,a?f("palette-success-main"):h.success.main,.5)),M(h.Slider,"warningTrack",_(ae,a?f("palette-warning-light"):h.warning.main,.5));let G=I?_(se,a?f("palette-background-default"):h.background.default,.985):$s(h.background.default,.98);M(h.SnackbarContent,"bg",G),M(h.SnackbarContent,"color",ln(()=>I?_m.text.primary:h.getContrastText(G))),M(h.SpeedDialAction,"fabHoverBg",$s(h.background.paper,.15)),M(h.StepConnector,"border",Q("palette-grey-600")),M(h.StepContent,"border",Q("palette-grey-600")),M(h.Switch,"defaultColor",Q("palette-grey-300")),M(h.Switch,"defaultDisabledColor",Q("palette-grey-600")),M(h.Switch,"primaryDisabledColor",_(ae,a?f("palette-primary-main"):h.primary.main,.55)),M(h.Switch,"secondaryDisabledColor",_(ae,a?f("palette-secondary-main"):h.secondary.main,.55)),M(h.Switch,"errorDisabledColor",_(ae,a?f("palette-error-main"):h.error.main,.55)),M(h.Switch,"infoDisabledColor",_(ae,a?f("palette-info-main"):h.info.main,.55)),M(h.Switch,"successDisabledColor",_(ae,a?f("palette-success-main"):h.success.main,.55)),M(h.Switch,"warningDisabledColor",_(ae,a?f("palette-warning-light"):h.warning.main,.55)),M(h.TableCell,"border",_(ae,ao(a?f("palette-divider"):h.divider,1),.68)),M(h.Tooltip,"bg",_(ao,a?f("palette-grey-700"):h.grey[700],.92))}a||(Nn(h.background,"default"),Nn(h.background,"paper"),Nn(h.common,"background"),Nn(h.common,"onBackground"),Nn(h,"divider")),Object.keys(h).forEach(G=>{let q=h[G];G!=="tonalOffset"&&!a&&q&&typeof q=="object"&&(q.main&&M(h[G],"mainChannel",ma(Xs(q.main))),q.light&&M(h[G],"lightChannel",ma(Xs(q.light))),q.dark&&M(h[G],"darkChannel",ma(Xs(q.dark))),q.contrastText&&M(h[G],"contrastTextChannel",ma(Xs(q.contrastText))),G==="text"&&(Nn(h[G],"primary"),Nn(h[G],"secondary")),G==="action"&&(q.active&&Nn(h[G],"active"),q.selected&&Nn(h[G],"selected")))})}),S=t.reduce((P,h)=>We(P,h),S);let v={prefix:i,disableCssColorScheme:o,shouldSkipGeneratingVar:s,getSelector:eb(S),enableContrastVars:a},{vars:D,generateThemeVars:N,generateStyleSheets:L}=wm(S,v);return S.vars=D,Object.entries(S.colorSchemes[S.defaultColorScheme]).forEach(([P,h])=>{S[P]=h}),S.generateThemeVars=N,S.generateStyleSheets=L,S.generateSpacing=function(){return ua(u.spacing,Ss(this))},S.getColorSchemeSelector=Sm(c),S.spacing=S.generateSpacing(),S.shouldSkipGeneratingVar=s,S.unstable_sxConfig={..._n,...u?.unstable_sxConfig},S.unstable_sx=function(h){return dr({sx:h,theme:this})},S.internal_cache={},S.toRuntimeSource=gu,S}var ln,m3,rb=d(()=>{ji();Mn();Bm();Oo();LE();Ms();qs();Fm();zE();KE();tb();Lm();zs();ln=e=>{try{return e()}catch{}},m3=(e="mui")=>du(e)});function nb(e,t,r){e.colorSchemes&&r&&(e.colorSchemes[t]={...r!==!0&&r,palette:zo({...r===!0?{}:r.palette,mode:t})})}function Ym(e={},...t){let{palette:r,cssVariables:n=!1,colorSchemes:o=r?void 0:{light:!0},defaultColorScheme:i=r?.mode,...a}=e,s=i||"light",c=o?.[s],l={...o,...r?{[s]:{...typeof c!="boolean"&&c,palette:r}}:void 0};if(n===!1){if(!("colorSchemes"in e))return Ks(e,...t);let u=r;"palette"in e||l[s]&&(l[s]!==!0?u=l[s].palette:s==="dark"&&(u={mode:"dark"}));let A=Ks({...e,palette:u},...t);return A.defaultColorScheme=s,A.colorSchemes=l,A.palette.mode==="light"&&(A.colorSchemes.light={...l.light!==!0&&l.light,palette:A.palette},nb(A,"dark",l.dark)),A.palette.mode==="dark"&&(A.colorSchemes.dark={...l.dark!==!0&&l.dark,palette:A.palette},nb(A,"light",l.light)),A}return!r&&!("light"in l)&&s==="light"&&(l.light=!0),jm({...a,colorSchemes:l,defaultColorScheme:s,...typeof n!="boolean"&&n},...t)}var ob=d(()=>{zs();rb();Fm()});var p3,ib,ab=d(()=>{"use client";ob();p3=Ym(),ib=p3});var sb,cb=d(()=>{sb="$$material"});function g3(e){return e!=="ownerState"&&e!=="theme"&&e!=="sx"&&e!=="as"}var lb,ub=d(()=>{lb=g3});var h3,fb,Ab=d(()=>{ub();h3=e=>lb(e)&&e!=="classes",fb=h3});var C3,$m,db=d(()=>{"use client";hm();ab();cb();Ab();C3=lu({themeId:sb,defaultTheme:ib,rootShouldForwardProp:fb}),$m=C3});var y3,mb=d(()=>{y3=p(O(),1);db()});var x3,pb,gb=d(()=>{Bm();x3=Au,pb=x3});function qm(e){return Im(e)}var mz,E3,hb=d(()=>{"use client";mz=p(k(),1);lE();E3=p(O(),1)});var Cb=d(()=>{hb()});function yb(e){return fa("MuiSvgIcon",e)}var bz,Jm=d(()=>{Aa();Am();bz=gr("MuiSvgIcon",["root","colorPrimary","colorSecondary","colorAction","colorError","colorDisabled","fontSizeInherit","fontSizeSmall","fontSizeMedium","fontSizeLarge"])});function Eb(e,t){return e==="always"?t:e==="system"?{"@media (prefers-reduced-motion: reduce)":t}:null}var xb,bb=d(()=>{xb={transition:"none"}});function S3(e,t){let r=t??xb;return Eb(e.motion?.reducedMotion,r)}function Ib(e,t=I3,r=w3){let n=e.transitions?.create?.(t,r),o=S3(e);if(n===void 0)return o??b3;let i={transition:n};return o?{...i,...o}:i}var b3,I3,w3,wb=d(()=>{bb();b3={},I3=["all"],w3={}});var hu,Cu,B3,v3,Sb,Wm,Bb=d(()=>{"use client";hu=p(k(),1);ml();WC();XC();mb();gb();Cb();Jm();wb();Cu=p(O(),1),B3=e=>{let{color:t,fontSize:r,classes:n}=e,o={root:["root",t!=="inherit"&&`color${xs(t)}`,`fontSize${xs(r)}`]};return pl(o,yb,n)},v3=$m("svg",{name:"MuiSvgIcon",slot:"Root",overridesResolver:(e,t)=>{let{ownerState:r}=e;return[t.root,r.color!=="inherit"&&t[`color${xs(r.color)}`],t[`fontSize${xs(r.fontSize)}`]]}})(pb(({theme:e})=>({userSelect:"none",width:"1em",height:"1em",display:"inline-block",flexShrink:0,...Ib(e,"fill",{duration:(e.vars??e).transitions?.duration?.shorter}),variants:[{props:t=>!t.hasSvgAsChild,style:{fill:"currentColor"}},{props:{fontSize:"inherit"},style:{fontSize:"inherit"}},{props:{fontSize:"small"},style:{fontSize:e.typography?.pxToRem?.(20)||"1.25rem"}},{props:{fontSize:"medium"},style:{fontSize:e.typography?.pxToRem?.(24)||"1.5rem"}},{props:{fontSize:"large"},style:{fontSize:e.typography?.pxToRem?.(35)||"2.1875rem"}},...Object.entries((e.vars??e).palette).filter(([,t])=>t&&t.main).map(([t])=>({props:{color:t},style:{color:(e.vars??e).palette?.[t]?.main}})),{props:{color:"action"},style:{color:(e.vars??e).palette?.action?.active}},{props:{color:"disabled"},style:{color:(e.vars??e).palette?.action?.disabled}},{props:{color:"inherit"},style:{color:void 0}}]}))),Sb=hu.forwardRef(function(t,r){let n=qm({props:t,name:"MuiSvgIcon"}),{children:o,className:i,color:a="inherit",component:s="svg",fontSize:c="medium",htmlColor:l,inheritViewBox:u=!1,titleAccess:A,viewBox:m="0 0 24 24",...f}=n,g=hu.isValidElement(o)&&o.type==="svg",y={...n,color:a,component:s,fontSize:c,instanceFontSize:t.fontSize,inheritViewBox:u,viewBox:m,hasSvgAsChild:g},E={};u||(E.viewBox=m);let b=B3(y);return(0,Cu.jsxs)(v3,{as:s,className:Vi(b.root,i),focusable:"false",color:l,"aria-hidden":A?void 0:!0,role:A?"img":void 0,ref:r,...E,...f,...g&&o.props,ownerState:y,children:[g?o.props.children:o,A?(0,Cu.jsx)("title",{children:A}):null]})});Sb.muiName="SvgIcon";Wm=Sb});function Y(e,t){function r(n,o){return(0,vb.jsx)(Wm,{"data-testid":void 0,ref:o,...n,children:e})}return r.muiName=Wm.muiName,yu.memo(yu.forwardRef(r))}var yu,vb,Tb=d(()=>{"use client";yu=p(k(),1);Bb();vb=p(O(),1)});var Qb=d(()=>{Tb();Jm()});var Ee=d(()=>{"use client";Qb()});var $=z((Yz,kb)=>{kb.exports=JBrowseExports["mobx-react"]});var Rt=z(($z,Db)=>{Db.exports=JBrowseExports["tss-react/mui"]});var zm=z((zz,Lb)=>{Lb.exports=JBrowseExports["@jbrowse/core/pluggableElementTypes"]});var Ca=z((Xz,Pb)=>{Pb.exports=JBrowseExports.mobx});function Eu(e){let{scrollX:t,msaAreaWidth:r,minimapHeight:n,colWidth:o,numColumns:i}=e,a=r/i/o,s=-t,c=s*a,l=(s+r)*a,u=Math.max(l-c,20),A=n-12,m=`${c+u},0 ${c},0 0,${A} ${r},${A}`;return{unit:a,s:c,w:u,polygonHeight:A,polygonPoints:m}}var Km=d(()=>{});var Xo,Ob,T3,Gb,Ub=d(()=>{Xo=p(k(),1),Ob=p($(),1);Km();T3=(0,Ob.observer)(({model:e})=>{let{msaAreaWidth:t}=e,{s:r,w:n,polygonPoints:o}=Eu(e),i="rgb(66, 119, 127)",a=.3;return Xo.default.createElement(Xo.default.Fragment,null,Xo.default.createElement("rect",{x:0,y:0,width:t,height:12,stroke:"#555",fill:"none"}),Xo.default.createElement("rect",{x:Math.max(0,r),y:0,width:n,height:12,fill:i,fillOpacity:a,stroke:"#555"}),Xo.default.createElement("g",{transform:`translate(0 ${12})`},Xo.default.createElement("polygon",{fill:i,fillOpacity:a,points:o})))}),Gb=T3});var Xm,Zm,Hb,Vb,bu,Iu,Zo,jb,wu,Yb,$b,qb,Jb,Wb,zb,Kb,Xb,Zs=d(()=>{Xm=new Set(["exon","CDS","five_prime_UTR","three_prime_UTR","UTR","intron"]),Zm=["#9fb6d4","#d4dcea"],Hb=!0,Vb=!1,bu=.2,Iu=1,Zo=80,jb=!0,wu="maeditor",Yb=!0,$b=!0,qb=!1,Jb=400,Wb=300,zb=!0,Kb=!0,Xb=!0});function xa({model:e,offsetY:t,blockSizeY:r}){let{leaves:n,rowHeight:o}=e,i=Math.max(0,Math.floor((t-o)/o)),a=Math.max(0,Math.ceil((t+r+o)/o));return n.slice(i,a)}var Su=d(()=>{});function Bu({model:e,offsetX:t,offsetY:r,ctx:n,highResScaleFactorOverride:o,blockSizeXOverride:i,blockSizeYOverride:a}){let{blockSize:s,rowHeight:c,highResScaleFactor:l,showDomains:u}=e;if(u){let A=o??l,m=i??s,f=a??s;n.resetTransform(),n.scale(A,A),n.translate(-t,c/2-r),M3({model:e,ctx:n,visibleLeaves:xa({model:e,offsetY:r,blockSizeY:f}),offsetX:t,blockWidth:m})}}function M3({model:e,ctx:t,visibleLeaves:r,offsetX:n,blockWidth:o}){let{subFeatureRows:i,colWidth:a,rowHeight:s,fillPalette:c,strokePalette:l,segmentLabels:u,showMsaLetters:A,domainBands:m}=e,f=i?4:s,g=!A&&!i&&f>=9,y=f+a,E=n-y,b=n+o+y;for(let x=0,B=r.length;x<B;x++){let I=r[x],w=I.x,S=m.get(I.data.name);if(S)for(let{annotation:v,startCol:D,endCol:N,stackIndex:L}of S){let{accession:P,strand:h}=v,Q=D*a,_=a*(N-D);if(Q+_>=E&&Q<=b){let G=w-s+(i?L*f:0);if(t.fillStyle=c[P],t.strokeStyle=l[P],h===void 0){t.fillRect(Q,G,_,f),t.strokeRect(Q,G,_,f);let q=g?u.get(P):void 0;if(q!==void 0&&x===0){let oe=Math.min(f-2,11);t.font=`${oe}px sans-serif`,t.measureText(q).width+2<=_&&(t.fillStyle="#222",t.textAlign="center",t.textBaseline="middle",t.fillText(q,Q+_/2,G+f/2))}}else _3({ctx:t,x:Q,t:G,w:_,h:f,strand:h})}}}}function _3({ctx:e,x:t,t:r,w:n,h:o,strand:i}){let a=i>0?1:-1,s=i>0?t:t+n,c=i>0?t+n:t;e.beginPath(),e.moveTo(s,r),e.lineTo(c,r),e.lineTo(c+a*o,r+o/2),e.lineTo(c,r+o),e.lineTo(s,r+o),e.closePath(),e.fill(),e.stroke()}var ep=d(()=>{Zs();Su()});function ec({offsetX:e,blockWidth:t,colWidth:r}){return{xStart:Math.max(0,Math.floor(e/r)),xEnd:Math.max(0,Math.ceil((e+t)/r))}}var tp=d(()=>{});function un(e,t,r=!1){e.font=e.font.replace(/(?:bold )?[\d.]+px/,`${r?"bold ":""}${t}px`)}var Ea=d(()=>{});var k3,Rn,at,hr,aI,Zb,rp,D3,vu,sI,cI,eI,tI,rI,tc,N3,R3,L3,F3,ip,nI,P3,np,op,oI,ap,rt,iI,Tu,rc=d(()=>{k3={grad:.9,turn:360,rad:360/(2*Math.PI)},Rn=function(e){return typeof e=="string"?e.length>0:typeof e=="number"},at=function(e,t,r){return t===void 0&&(t=0),r===void 0&&(r=Math.pow(10,t)),Math.round(r*e)/r+0},hr=function(e,t,r){return t===void 0&&(t=0),r===void 0&&(r=1),e>r?r:e>t?e:t},aI=function(e){return(e=isFinite(e)?e%360:0)>0?e:e+360},Zb=function(e){return{r:hr(e.r,0,255),g:hr(e.g,0,255),b:hr(e.b,0,255),a:hr(e.a)}},rp=function(e){return{r:at(e.r),g:at(e.g),b:at(e.b),a:at(e.a,3)}},D3=/^#([0-9a-f]{3,8})$/i,vu=function(e){var t=e.toString(16);return t.length<2?"0"+t:t},sI=function(e){var t=e.r,r=e.g,n=e.b,o=e.a,i=Math.max(t,r,n),a=i-Math.min(t,r,n),s=a?i===t?(r-n)/a:i===r?2+(n-t)/a:4+(t-r)/a:0;return{h:60*(s<0?s+6:s),s:i?a/i*100:0,v:i/255*100,a:o}},cI=function(e){var t=e.h,r=e.s,n=e.v,o=e.a;t=t/360*6,r/=100,n/=100;var i=Math.floor(t),a=n*(1-r),s=n*(1-(t-i)*r),c=n*(1-(1-t+i)*r),l=i%6;return{r:255*[n,s,a,a,c,n][l],g:255*[c,n,n,s,a,a][l],b:255*[a,a,c,n,n,s][l],a:o}},eI=function(e){return{h:aI(e.h),s:hr(e.s,0,100),l:hr(e.l,0,100),a:hr(e.a)}},tI=function(e){return{h:at(e.h),s:at(e.s),l:at(e.l),a:at(e.a,3)}},rI=function(e){return cI((r=(t=e).s,{h:t.h,s:(r*=((n=t.l)<50?n:100-n)/100)>0?2*r/(n+r)*100:0,v:n+r,a:t.a}));var t,r,n},tc=function(e){return{h:(t=sI(e)).h,s:(o=(200-(r=t.s))*(n=t.v)/100)>0&&o<200?r*n/100/(o<=100?o:200-o)*100:0,l:o/2,a:t.a};var t,r,n,o},N3=/^hsla?\(\s*([+-]?\d*\.?\d+)(deg|rad|grad|turn)?\s*,\s*([+-]?\d*\.?\d+)%\s*,\s*([+-]?\d*\.?\d+)%\s*(?:,\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,R3=/^hsla?\(\s*([+-]?\d*\.?\d+)(deg|rad|grad|turn)?\s+([+-]?\d*\.?\d+)%\s+([+-]?\d*\.?\d+)%\s*(?:\/\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,L3=/^rgba?\(\s*([+-]?\d*\.?\d+)(%)?\s*,\s*([+-]?\d*\.?\d+)(%)?\s*,\s*([+-]?\d*\.?\d+)(%)?\s*(?:,\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,F3=/^rgba?\(\s*([+-]?\d*\.?\d+)(%)?\s+([+-]?\d*\.?\d+)(%)?\s+([+-]?\d*\.?\d+)(%)?\s*(?:\/\s*([+-]?\d*\.?\d+)(%)?\s*)?\)$/i,ip={string:[[function(e){var t=D3.exec(e);return t?(e=t[1]).length<=4?{r:parseInt(e[0]+e[0],16),g:parseInt(e[1]+e[1],16),b:parseInt(e[2]+e[2],16),a:e.length===4?at(parseInt(e[3]+e[3],16)/255,2):1}:e.length===6||e.length===8?{r:parseInt(e.substr(0,2),16),g:parseInt(e.substr(2,2),16),b:parseInt(e.substr(4,2),16),a:e.length===8?at(parseInt(e.substr(6,2),16)/255,2):1}:null:null},"hex"],[function(e){var t=L3.exec(e)||F3.exec(e);return t?t[2]!==t[4]||t[4]!==t[6]?null:Zb({r:Number(t[1])/(t[2]?100/255:1),g:Number(t[3])/(t[4]?100/255:1),b:Number(t[5])/(t[6]?100/255:1),a:t[7]===void 0?1:Number(t[7])/(t[8]?100:1)}):null},"rgb"],[function(e){var t=N3.exec(e)||R3.exec(e);if(!t)return null;var r,n,o=eI({h:(r=t[1],n=t[2],n===void 0&&(n="deg"),Number(r)*(k3[n]||1)),s:Number(t[3]),l:Number(t[4]),a:t[5]===void 0?1:Number(t[5])/(t[6]?100:1)});return rI(o)},"hsl"]],object:[[function(e){var t=e.r,r=e.g,n=e.b,o=e.a,i=o===void 0?1:o;return Rn(t)&&Rn(r)&&Rn(n)?Zb({r:Number(t),g:Number(r),b:Number(n),a:Number(i)}):null},"rgb"],[function(e){var t=e.h,r=e.s,n=e.l,o=e.a,i=o===void 0?1:o;if(!Rn(t)||!Rn(r)||!Rn(n))return null;var a=eI({h:Number(t),s:Number(r),l:Number(n),a:Number(i)});return rI(a)},"hsl"],[function(e){var t=e.h,r=e.s,n=e.v,o=e.a,i=o===void 0?1:o;if(!Rn(t)||!Rn(r)||!Rn(n))return null;var a=(function(s){return{h:aI(s.h),s:hr(s.s,0,100),v:hr(s.v,0,100),a:hr(s.a)}})({h:Number(t),s:Number(r),v:Number(n),a:Number(i)});return cI(a)},"hsv"]]},nI=function(e,t){for(var r=0;r<t.length;r++){var n=t[r][0](e);if(n)return[n,t[r][1]]}return[null,void 0]},P3=function(e){return typeof e=="string"?nI(e.trim(),ip.string):typeof e=="object"&&e!==null?nI(e,ip.object):[null,void 0]},np=function(e,t){var r=tc(e);return{h:r.h,s:hr(r.s+100*t,0,100),l:r.l,a:r.a}},op=function(e){return(299*e.r+587*e.g+114*e.b)/1e3/255},oI=function(e,t){var r=tc(e);return{h:r.h,s:r.s,l:hr(r.l+100*t,0,100),a:r.a}},ap=(function(){function e(t){this.parsed=P3(t)[0],this.rgba=this.parsed||{r:0,g:0,b:0,a:1}}return e.prototype.isValid=function(){return this.parsed!==null},e.prototype.brightness=function(){return at(op(this.rgba),2)},e.prototype.isDark=function(){return op(this.rgba)<.5},e.prototype.isLight=function(){return op(this.rgba)>=.5},e.prototype.toHex=function(){return t=rp(this.rgba),r=t.r,n=t.g,o=t.b,a=(i=t.a)<1?vu(at(255*i)):"","#"+vu(r)+vu(n)+vu(o)+a;var t,r,n,o,i,a},e.prototype.toRgb=function(){return rp(this.rgba)},e.prototype.toRgbString=function(){return t=rp(this.rgba),r=t.r,n=t.g,o=t.b,(i=t.a)<1?"rgba("+r+", "+n+", "+o+", "+i+")":"rgb("+r+", "+n+", "+o+")";var t,r,n,o,i},e.prototype.toHsl=function(){return tI(tc(this.rgba))},e.prototype.toHslString=function(){return t=tI(tc(this.rgba)),r=t.h,n=t.s,o=t.l,(i=t.a)<1?"hsla("+r+", "+n+"%, "+o+"%, "+i+")":"hsl("+r+", "+n+"%, "+o+"%)";var t,r,n,o,i},e.prototype.toHsv=function(){return t=sI(this.rgba),{h:at(t.h),s:at(t.s),v:at(t.v),a:at(t.a,3)};var t},e.prototype.invert=function(){return rt({r:255-(t=this.rgba).r,g:255-t.g,b:255-t.b,a:t.a});var t},e.prototype.saturate=function(t){return t===void 0&&(t=.1),rt(np(this.rgba,t))},e.prototype.desaturate=function(t){return t===void 0&&(t=.1),rt(np(this.rgba,-t))},e.prototype.grayscale=function(){return rt(np(this.rgba,-1))},e.prototype.lighten=function(t){return t===void 0&&(t=.1),rt(oI(this.rgba,t))},e.prototype.darken=function(t){return t===void 0&&(t=.1),rt(oI(this.rgba,-t))},e.prototype.rotate=function(t){return t===void 0&&(t=15),this.hue(this.hue()+t)},e.prototype.alpha=function(t){return typeof t=="number"?rt({r:(r=this.rgba).r,g:r.g,b:r.b,a:t}):at(this.rgba.a,3);var r},e.prototype.hue=function(t){var r=tc(this.rgba);return typeof t=="number"?rt({h:t,s:r.s,l:r.l,a:r.a}):at(r.h)},e.prototype.isEqual=function(t){return this.toHex()===rt(t).toHex()},e})(),rt=function(e){return e instanceof ap?e:new ap(e)},iI=[],Tu=function(e){e.forEach(function(t){iI.indexOf(t)<0&&(t(ap,ip),iI.push(t))})}});function lI(e){e.prototype.luminance=function(){return t=cp(this.rgba),(r=2)===void 0&&(r=0),n===void 0&&(n=Math.pow(10,r)),Math.round(n*t)/n+0;var t,r,n},e.prototype.contrast=function(t){t===void 0&&(t="#FFF");var r,n,o,i,a,s,c,l=t instanceof e?t:new e(t);return i=this.rgba,a=l.toRgb(),s=cp(i),c=cp(a),r=s>c?(s+.05)/(c+.05):(c+.05)/(s+.05),(n=2)===void 0&&(n=0),o===void 0&&(o=Math.pow(10,n)),Math.floor(o*r)/o+0},e.prototype.isReadable=function(t,r){return t===void 0&&(t="#FFF"),r===void 0&&(r={}),this.contrast(t)>=(s=(a=(n=r).size)===void 0?"normal":a,(i=(o=n.level)===void 0?"AA":o)==="AAA"&&s==="normal"?7:i==="AA"&&s==="large"?3:4.5);var n,o,i,a,s}}var sp,cp,uI=d(()=>{sp=function(e){var t=e/255;return t<.04045?t/12.92:Math.pow((t+.055)/1.055,2.4)},cp=function(e){return .2126*sp(e.r)+.7152*sp(e.g)+.0722*sp(e.b)}});function Qu(e,t){var r={white:"#ffffff",bisque:"#ffe4c4",blue:"#0000ff",cadetblue:"#5f9ea0",chartreuse:"#7fff00",chocolate:"#d2691e",coral:"#ff7f50",antiquewhite:"#faebd7",aqua:"#00ffff",azure:"#f0ffff",whitesmoke:"#f5f5f5",papayawhip:"#ffefd5",plum:"#dda0dd",blanchedalmond:"#ffebcd",black:"#000000",gold:"#ffd700",goldenrod:"#daa520",gainsboro:"#dcdcdc",cornsilk:"#fff8dc",cornflowerblue:"#6495ed",burlywood:"#deb887",aquamarine:"#7fffd4",beige:"#f5f5dc",crimson:"#dc143c",cyan:"#00ffff",darkblue:"#00008b",darkcyan:"#008b8b",darkgoldenrod:"#b8860b",darkkhaki:"#bdb76b",darkgray:"#a9a9a9",darkgreen:"#006400",darkgrey:"#a9a9a9",peachpuff:"#ffdab9",darkmagenta:"#8b008b",darkred:"#8b0000",darkorchid:"#9932cc",darkorange:"#ff8c00",darkslateblue:"#483d8b",gray:"#808080",darkslategray:"#2f4f4f",darkslategrey:"#2f4f4f",deeppink:"#ff1493",deepskyblue:"#00bfff",wheat:"#f5deb3",firebrick:"#b22222",floralwhite:"#fffaf0",ghostwhite:"#f8f8ff",darkviolet:"#9400d3",magenta:"#ff00ff",green:"#008000",dodgerblue:"#1e90ff",grey:"#808080",honeydew:"#f0fff0",hotpink:"#ff69b4",blueviolet:"#8a2be2",forestgreen:"#228b22",lawngreen:"#7cfc00",indianred:"#cd5c5c",indigo:"#4b0082",fuchsia:"#ff00ff",brown:"#a52a2a",maroon:"#800000",mediumblue:"#0000cd",lightcoral:"#f08080",darkturquoise:"#00ced1",lightcyan:"#e0ffff",ivory:"#fffff0",lightyellow:"#ffffe0",lightsalmon:"#ffa07a",lightseagreen:"#20b2aa",linen:"#faf0e6",mediumaquamarine:"#66cdaa",lemonchiffon:"#fffacd",lime:"#00ff00",khaki:"#f0e68c",mediumseagreen:"#3cb371",limegreen:"#32cd32",mediumspringgreen:"#00fa9a",lightskyblue:"#87cefa",lightblue:"#add8e6",midnightblue:"#191970",lightpink:"#ffb6c1",mistyrose:"#ffe4e1",moccasin:"#ffe4b5",mintcream:"#f5fffa",lightslategray:"#778899",lightslategrey:"#778899",navajowhite:"#ffdead",navy:"#000080",mediumvioletred:"#c71585",powderblue:"#b0e0e6",palegoldenrod:"#eee8aa",oldlace:"#fdf5e6",paleturquoise:"#afeeee",mediumturquoise:"#48d1cc",mediumorchid:"#ba55d3",rebeccapurple:"#663399",lightsteelblue:"#b0c4de",mediumslateblue:"#7b68ee",thistle:"#d8bfd8",tan:"#d2b48c",orchid:"#da70d6",mediumpurple:"#9370db",purple:"#800080",pink:"#ffc0cb",skyblue:"#87ceeb",springgreen:"#00ff7f",palegreen:"#98fb98",red:"#ff0000",yellow:"#ffff00",slateblue:"#6a5acd",lavenderblush:"#fff0f5",peru:"#cd853f",palevioletred:"#db7093",violet:"#ee82ee",teal:"#008080",slategray:"#708090",slategrey:"#708090",aliceblue:"#f0f8ff",darkseagreen:"#8fbc8f",darkolivegreen:"#556b2f",greenyellow:"#adff2f",seagreen:"#2e8b57",seashell:"#fff5ee",tomato:"#ff6347",silver:"#c0c0c0",sienna:"#a0522d",lavender:"#e6e6fa",lightgreen:"#90ee90",orange:"#ffa500",orangered:"#ff4500",steelblue:"#4682b4",royalblue:"#4169e1",turquoise:"#40e0d0",yellowgreen:"#9acd32",salmon:"#fa8072",saddlebrown:"#8b4513",sandybrown:"#f4a460",rosybrown:"#bc8f8f",darksalmon:"#e9967a",lightgoldenrodyellow:"#fafad2",snow:"#fffafa",lightgrey:"#d3d3d3",lightgray:"#d3d3d3",dimgray:"#696969",dimgrey:"#696969",olivedrab:"#6b8e23",olive:"#808000"},n={};for(var o in r)n[r[o]]=o;var i={};e.prototype.toName=function(a){if(!(this.rgba.a||this.rgba.r||this.rgba.g||this.rgba.b))return"transparent";var s,c,l=n[this.toHex()];if(l)return l;if(a?.closest){var u=this.toRgb(),A=1/0,m="black";if(!i.length)for(var f in r)i[f]=new e(r[f]).toRgb();for(var g in r){var y=(s=u,c=i[g],Math.pow(s.r-c.r,2)+Math.pow(s.g-c.g,2)+Math.pow(s.b-c.b,2));y<A&&(A=y,m=g)}return m}},t.string.push([function(a){var s=a.toLowerCase(),c=s==="transparent"?"#0000":r[s];return c?new e(c).toRgb():null},"name"])}var lp=d(()=>{});function AI(e,t){let r=`${e}|${t}`,n=fI.get(r);if(n!==void 0)return n;let o=rt(e);if(!o.isReadable(t)){let a=rt(t).luminance()<.5;for(let s=0;s<40&&!o.isReadable(t);s++)o=a?o.lighten(.05):o.darken(.05)}let i=o.toHex();return fI.set(r,i),i}function ba(e,t){return Object.fromEntries(Object.entries(e).map(t))}function nc(e,t){return ba(e,([r,n])=>[r,t.palette.getContrastText(rt(n).toHex())])}function up(e,t){if(e.length===0)return t;let r=[],n=0;for(let o of e)o>n&&r.push(t.slice(n,o)),n=o+1;return n<t.length&&r.push(t.slice(n)),r.join("")}function dI(e,t){let r=[],n=e.length,o=0,i=0,a=-1,s=[];for(let c=0;c<t.length;c++)i<n&&e[i]===c?(t.charCodeAt(c)-45>>>0<=1||(a===o?s.push(t[c]):(s.length>0&&r.push({pos:a,letters:s.join("")}),a=o,s=[t[c]])),i++):o++;return s.length>0&&r.push({pos:a,letters:s.join("")}),r}function fp(e){return e.end-e.start}function Mu(e){return e==="-"||e==="."}var fI,so=d(()=>{rc();uI();lp();Tu([Qu,lI]);fI=new Map});function _u({model:e,offsetX:t,offsetY:r,contrastScheme:n,ctx:o,theme:i,highResScaleFactorOverride:a,blockSizeXOverride:s,blockSizeYOverride:c}){let{colWidth:l,blockSize:u,rowHeight:A,fontSize:m,highResScaleFactor:f,actuallyShowDomains:g,bgColor:y}=e,E=a??f,b=s??u,x=c??u;o.resetTransform(),o.scale(E,E),o.translate(-t,A/2-r),o.textAlign="center",o.textBaseline="alphabetic",un(o,m,!y);let{xStart:B,xEnd:I}=ec({offsetX:t,blockWidth:b,colWidth:l}),w=xa({model:e,offsetY:r,blockSizeY:x}),{relativeTo:S,columns:v}=e,D=S?v.get(S)?.slice(B,I):null;U3({model:e,ctx:o,theme:i,contrastScheme:n,xStart:B,xEnd:I,visibleLeaves:w,referenceSeq:D,drawTiles:!g}),H3({model:e,ctx:o,xStart:B,xEnd:I,visibleLeaves:w}),o.resetTransform()}function O3(e){let{colorSchemeName:t,colorScheme:r,colClustalX:n,colConsensus:o}=e;return t==="clustalx_protein_dynamic"?(i,a)=>n[i][a]:t==="percent_identity_dynamic"?(i,a)=>{let s=o[i];return a===s.letter?s.color:void 0}:(i,a)=>r[a]}function G3(e,t){return new Map(Object.entries(e.fillPalette).map(([r,n])=>[r,t.palette.getContrastText(n)]))}function U3({model:e,ctx:t,theme:r,contrastScheme:n,visibleLeaves:o,xStart:i,xEnd:a,referenceSeq:s,drawTiles:c}){let{bgColor:l,columns:u,colWidth:A,rowHeight:m,relativeTo:f,showMsaLetters:g,subFeatureRows:y,domainBandsByStart:E}=e,b=c&&l;if(b||g){let x=O3(e),B=i*A,I=A/2,w=m/4,S=!c&&!y,v=S?G3(e,r):void 0;for(let D=0,N=o.length;D<N;D++){let L=o[D],{name:P}=L.data,h=L.x,Q=u.get(P)?.slice(i,a);if(Q){let _=h-m,G=h-w,q=S?E.get(P):void 0,oe=0;for(let tt=0,_i=Q.length;tt<_i;tt++){let lr=i+tt,ue=Q[tt],Mr=tt*A+B,ur=s&&P!==f&&ue===s[tt],Xr=x(lr,ue);if(b&&(t.fillStyle=ur?r.palette.action.hover:Xr||r.palette.background.default,t.fillRect(Mr,_,A,m)),g){for(;q&&oe<q.length&&q[oe].endCol<=lr;)oe++;let vn=q?.[oe];t.fillStyle=vn&&vn.startCol<=lr?v.get(vn.annotation.accession):b?n[ue]??"black":!c||!Xr?r.palette.text.primary:AI(Xr,r.palette.background.default),t.fillText(ur?".":ue,Mr+I,G)}}}}}}function H3({model:e,ctx:t,visibleLeaves:r,xStart:n,xEnd:o}){let{bgColor:i,hideGapsEffective:a}=e;a&&(t.lineWidth=1,t.strokeStyle="#f0f",mI({visibleLeaves:r,xStart:n,ctx:t,model:e,xEnd:o,offset:0}),t.strokeStyle=i?"#fff":"#000",mI({visibleLeaves:r,xStart:n,ctx:t,model:e,xEnd:o,offset:-1}))}function mI({model:e,ctx:t,visibleLeaves:r,xStart:n,xEnd:o,offset:i}){let{colWidth:s,rowHeight:c,insertionPositions:l}=e;for(let u of r){let{name:A}=u.data,m=l.get(A);if(m){let f=u.x;for(let{pos:g}of m)if(g>=n&&g<o){let y=g*s,E=f-c,b=f;t.beginPath(),t.moveTo(y+i,E+i);let x=E,B=!0;for(;x<b;){let I=Math.min(x+2,b),w=B?y+1:y-1;t.lineTo(w+i,I+i),x=I,B=!B}t.stroke()}}}}var Ap=d(()=>{tp();Ea();so();Su()});function dp({ctx:e,values:t,color:r,colWidth:n,trackHeight:o,offsetX:i,blockSize:a}){let{xStart:s,xEnd:c}=ec({offsetX:i,blockWidth:a,colWidth:n});e.fillStyle=r;for(let l=s;l<c&&l<t.length;l++){let A=t[l]*o,m=l*n;e.fillRect(m,o-A,n,A)}}function mp(e,t){return t==="property-conservation"?e.propertyConservation:e.conservation}function pp({ctx:e,data:t,colorScheme:r,contrastScheme:n,bgColor:o,colWidth:i,rowHeight:a,offsetX:s,blockSize:c}){let{xStart:l,xEnd:u}=ec({offsetX:s,blockWidth:c,colWidth:i}),A=t?.slice(l,u);for(let m=0;A&&m<A.length;m++){let f=A[m],g=f.toUpperCase();if(o){let y=(l+m)*i;e.fillStyle=r[g]||"white",e.fillRect(y,0,i,a),a>=10&&i>=a/2&&(e.fillStyle=n[g]||"black",e.fillText(f,y+i/2,a/2+1))}}}function V3({model:e,ctx:t,track:r,offsetX:n,offsetY:o,trackHeight:i,blockSizeXOverride:a,highResScaleFactorOverride:s}){let{blockSize:c,colWidth:l,highResScaleFactor:u}=e,A=a??c,m=s??u;t.resetTransform(),t.scale(m,m),t.translate(-n,o),dp({ctx:t,values:mp(e,r.model.id),color:r.model.barColor??"gray",colWidth:l,trackHeight:i,offsetX:n,blockSize:A}),t.resetTransform()}function j3({model:e,ctx:t,track:r,offsetX:n,offsetY:o,contrastScheme:i,blockSizeXOverride:a,highResScaleFactorOverride:s}){let{blockSize:c,bgColor:l,colorScheme:u,colWidth:A,fontSize:m,rowHeight:f,highResScaleFactor:g}=e,{customColorScheme:y,data:E}=r.model,b=y??u,x=a??c,B=s??g;t.resetTransform(),t.scale(B,B),t.translate(-n,o),t.textAlign="center",un(t,m),pp({ctx:t,data:E,colorScheme:b,contrastScheme:i,bgColor:l,colWidth:A,rowHeight:f,offsetX:n,blockSize:x}),t.resetTransform()}function pI({model:e,ctx:t,offsetX:r,contrastScheme:n,blockSizeXOverride:o,highResScaleFactorOverride:i}){let{turnedOnTracks:a}=e,s=0;for(let c of a){let l=c.model.height;c.model.barColor!==void 0?V3({model:e,ctx:t,track:c,offsetX:r,offsetY:s,trackHeight:l,blockSizeXOverride:o,highResScaleFactorOverride:i}):j3({model:e,ctx:t,track:c,offsetX:r,offsetY:s,contrastScheme:n,blockSizeXOverride:o,highResScaleFactorOverride:i}),s+=l}}var ku=d(()=>{Ea();tp()});function ei(e){let t=[],r=[e];for(;r.length>0;){let n=r.pop();if(t.push(n),n.children)for(let o=n.children.length-1;o>=0;o--)r.push(n.children[o])}return t}function Y3(e){let t=ei(e);for(let r=t.length-1;r>=0;r--){let n=t[r],o=0;if(n.children)for(let i of n.children)i.height+1>o&&(o=i.height+1);n.height=o}}function gI(e,t){let r={data:e,children:null,parent:null,depth:0,height:0},n=[r];for(;n.length>0;){let o=n.pop(),i=t(o.data);if(i?.length){o.children=i.map(a=>({data:a,children:null,parent:o,depth:o.depth+1,height:0}));for(let a of o.children)n.push(a)}}return Y3(r),r}function hI(e,t){let r=ei(e);for(let n=r.length-1;n>=0;n--){let o=r[n],i=t(o.data);if(o.children)for(let a of o.children)i+=a.value;o.value=i}return e}function CI(e,t){let r=[e];for(;r.length>0;){let n=r.pop();if(n.children){n.children.sort(t);for(let o of n.children)r.push(o)}}return e}function Du(e,t){let r=[e],n;for(;r.length>0&&n===void 0;){let o=r.pop();if(t(o))n=o;else if(o.children)for(let i=o.children.length-1;i>=0;i--)r.push(o.children[i])}return n}function oc(e){let t=[],r=[e];for(;r.length>0;){let n=r.pop();if(n.children)for(let o=n.children.length-1;o>=0;o--)r.push(n.children[o]);else t.push(n)}return t}function yI(e){let t=[];return gp(e,(r,n)=>{t.push({source:r,target:n})}),t}function gp(e,t){let r=[e];for(;r.length>0;){let n=r.pop();if(n.children)for(let o=n.children.length-1;o>=0;o--){let i=n.children[o];t(n,i),r.push(i)}}}function ic(e,t){for(let r of ei(e))t(r)}function xI(e,t,r){let n=oc(e),o=n.length,i=t/o;for(let l=0;l<o;l++)n[l].x=(l+.5)*i;let a=ei(e);for(let l=a.length-1;l>=0;l--){let u=a[l];if(u.children){let A=0;for(let m of u.children)A+=m.x;u.x=A/u.children.length}}let s=e.height,c=[{node:e,depth:0}];for(;c.length>0;){let{node:l,depth:u}=c.pop();if(l.y=s===0?r:u/s*r,l.children)for(let A of l.children)c.push({node:A,depth:u+1})}}function EI(e){e.children&&(ac(e),e._children=e.children,e.children=null)}function bI(e){let t=e._children??e.children,r=1/0,n=0;if(t){let o=t.map(i=>({node:i,acc:Math.max(i.data.length??0,0)}));for(;o.length>0;){let{node:i,acc:a}=o.pop(),s=i.children??i._children;if(s?.length)for(let c of s)o.push({node:c,acc:a+Math.max(c.data.length??0,0)});else r=Math.min(r,a),n=Math.max(n,a)}}return{min:r===1/0?0:r,max:n}}function ac(e){if(e.depthToLeaf===void 0){let t=ei(e);for(let r=t.length-1;r>=0;r--){let n=t[r];if(n.depthToLeaf===void 0){let o=0;if(n.children)for(let i of n.children)o=Math.max(o,1+i.depthToLeaf);n.depthToLeaf=o}}}return e.depthToLeaf}function II(e){let t=0;for(let r of ei(e))t=Math.max(t,r.len||0);return t}function wI(e){let t=ei(e),r=new Map;for(let n=t.length-1;n>=0;n--){let o=t[n],i=0;if(o.children)for(let a of o.children)i=Math.max(i,r.get(a));r.set(o,(o.data.length||0)+i)}return r.get(e)}function SI(e,t,r){let n=[{node:e,y0:t}];for(;n.length>0;){let{node:o,y0:i}=n.pop(),a=i+Math.max(o.data.length||0,0);if(o.len=a*r,o.children)for(let s of o.children)n.push({node:s,y0:a})}}var hp=d(()=>{});function yp(e,t,r){return e>t-BI&&e<t+r+BI}function sc(e,t,r,n){if(t)return e.len;if(n===0)return 0;let o=ac(e);return(n-o)/n*r}function $3({offsetY:e,ctx:t,model:r,theme:n,maxBranchLen:o,maxDepthToLeaf:i,blockSizeYOverride:a}){let{hierarchy:s,showBranchLenEffective:c,blockSize:l}=r,u=a??l;t.strokeStyle=n.palette.text.primary,gp(s,(A,m)=>{let f=A.x,g=m.x,y=sc(m,c,o,i),E=sc(A,c,o,i);if(y===void 0||E===void 0)return;let b=Math.min(f,g),x=Math.max(f,g);e+u>=b&&x>=e&&(t.beginPath(),t.moveTo(E,f),t.lineTo(E,g),t.lineTo(y,g),t.stroke())})}function q3({ctx:e,clickMap:t,offsetY:r,model:n,theme:o,maxBranchLen:i,maxDepthToLeaf:a,blockSizeYOverride:s}){let{hierarchy:c,showBranchLenEffective:l,collapsed:u,blockSize:A,rowHeight:m,fontSize:f,marginLeft:g}=n,y=s??A,E=Math.max(2,m*.42);ic(c,b=>{let{id:x,name:B}=b.data;if(u.includes(x)){let I=sc(b,l,i,a),w=b.x,S=yp(w,r,y),v=l?b.collapsedTipXFar??i:i;if(I!==void 0&&S&&v>I){e.beginPath(),e.moveTo(I,w),e.lineTo(v,w-E),e.lineTo(v,w+E),e.closePath(),e.fillStyle=o.palette.action.disabled,e.fill(),e.strokeStyle=o.palette.text.primary,e.stroke();let D=b.value;D!==void 0&&m>=8&&(e.fillStyle=o.palette.text.primary,e.textAlign="left",e.fillText(`${D}`,v+3,w+f/4));let N=B===x?"Collapsed clade":B;t?.insert({minX:I+g,maxX:v+g,minY:w-E,maxY:w+E,branch:!0,id:x,name:D===void 0?N:`${N} (${D} tips)`})}}})}function J3({ctx:e,clickMap:t,offsetY:r,model:n,maxBranchLen:o,maxDepthToLeaf:i,blockSizeYOverride:a}){let{hierarchy:s,showBranchLenEffective:c,collapsed:l,blockSize:u,marginLeft:A}=n,m=a??u;ic(s,f=>{let g=sc(f,c,o,i);if(g===void 0)return;let{data:y}=f,E=f.x,{id:b,name:x}=y;if(f.height>=1&&yp(E,r,m)){let B=l.includes(b);e.strokeStyle="black",e.fillStyle=B?"black":"white",e.beginPath(),e.arc(g,E,ti,0,2*Math.PI),e.fill(),e.stroke(),B||t?.insert({minX:g-ti+A,maxX:g-ti+Cp+A,minY:E-ti,maxY:E-ti+Cp,branch:!0,id:b,name:x})}})}function W3({theme:e,model:t,offsetY:r,ctx:n,clickMap:o,maxBranchLen:i,maxDepthToLeaf:a,blockSizeYOverride:s}){let{fontSize:c,showBranchLenEffective:l,treeMetadata:u,blockSize:A,labelsAlignRight:m,drawTree:f,treeAreaWidth:g,treeAreaWidthMinusMargin:y,marginLeft:E,noTree:b,labelWidthMap:x,collapsed:B}=t,I=xa({model:t,offsetY:r,blockSizeY:s??t.blockSize}),w=s??A,S=n.measureText("M").width;m?(n.textAlign="right",n.setLineDash([1,3]),n.strokeStyle=e.palette.text.primary):n.textAlign="start";for(let v of I){let{data:{name:D,id:N}}=v,L=v.x,P=u[D]?.genome||D;if(!(B.includes(N)&&D===N)&&yp(L,r,w)){let Q=L+c/4,_=0;b||(_=sc(v,l,i,a)??0);let G=x.get(D)??n.measureText(P).width;if(n.fillStyle=e.palette.text.primary,m){let oe=y-2;f&&!b&&(n.beginPath(),n.moveTo(_+ti+2,L),n.lineTo(oe-2-G,L),n.stroke()),n.fillText(P,oe,Q),o?.insert({minX:g-G,maxX:g,minY:Q-S,maxY:Q,name:D,id:N})}else{let q=b?2:_+Cp;n.fillText(P,q,Q),o?.insert({minX:q+E,maxX:q+G+E,minY:Q-S,maxY:Q,name:D,id:N})}}}n.setLineDash([])}function Ru({model:e,clickMap:t,ctx:r,offsetY:n,theme:o,highResScaleFactorOverride:i,blockSizeYOverride:a}){t?.clear();let{noTree:s,drawTree:c,drawNodeBubbles:l,highResScaleFactor:u,fontSize:A,showTreeText:m,marginLeft:f,rowHeight:g}=e;r.resetTransform();let y=i??u;r.scale(y,y),r.translate(f,-n),un(r,A);let{maxBranchLength:E,maxDepthToLeaf:b}=e;!s&&c&&($3({ctx:r,offsetY:n,model:e,theme:o,maxBranchLen:E,maxDepthToLeaf:b,blockSizeYOverride:a}),q3({ctx:r,clickMap:t,offsetY:n,model:e,theme:o,maxBranchLen:E,maxDepthToLeaf:b,blockSizeYOverride:a}),l&&J3({ctx:r,offsetY:n,clickMap:t,model:e,maxBranchLen:E,maxDepthToLeaf:b,blockSizeYOverride:a})),m&&W3({ctx:r,offsetY:n,model:e,clickMap:t,theme:o,maxBranchLen:E,maxDepthToLeaf:b,blockSizeYOverride:a}),t?.finish()}var Nu,BI,ti,Cp,Lu=d(()=>{hp();Ea();Su();Nu=600,BI=5,ti=2.5,Cp=ti*2});var QI={};bt(QI,{Context:()=>bp});function vI(e){return!e||typeof e=="string"?e:e+""}function Lr(e,t){let r=Object.keys(t);for(let n of r)e=e.replace(new RegExp("\\{"+n+"\\}","gi"),t[n]);return e}function xp(e){if(!e)throw new Error("cannot create a random attribute name for an undefined object");let t="ABCDEFGHIJKLMNOPQRSTUVWXTZabcdefghiklmnopqrstuvwxyz",r="";do{r="";for(let n=0;n<12;n++)r+=t[Math.floor(Math.random()*t.length)]}while(e[r]);return r}function z3(e,t=10){let r={},n=e.split(",");for(let o=0;o<n.length;o+=2){let i="&"+n[o+1]+";",a=parseInt(n[o],t);r[i]="&#"+a+";"}return r["\\xa0"]="&#160;",r}function K3(e){let t={left:"start",right:"end",center:"middle",start:"start",end:"end"};return t[e]||t.start}function X3(e){let t={alphabetic:"alphabetic",hanging:"hanging",top:"text-before-edge",bottom:"text-after-edge",middle:"central"};return t[e]||t.alphabetic}var TI,cc,lc,Ep,bp,MI=d(()=>{TI=z3("50,nbsp,51,iexcl,52,cent,53,pound,54,curren,55,yen,56,brvbar,57,sect,58,uml,59,copy,5a,ordf,5b,laquo,5c,not,5d,shy,5e,reg,5f,macr,5g,deg,5h,plusmn,5i,sup2,5j,sup3,5k,acute,5l,micro,5m,para,5n,middot,5o,cedil,5p,sup1,5q,ordm,5r,raquo,5s,frac14,5t,frac12,5u,frac34,5v,iquest,60,Agrave,61,Aacute,62,Acirc,63,Atilde,64,Auml,65,Aring,66,AElig,67,Ccedil,68,Egrave,69,Eacute,6a,Ecirc,6b,Euml,6c,Igrave,6d,Iacute,6e,Icirc,6f,Iuml,6g,ETH,6h,Ntilde,6i,Ograve,6j,Oacute,6k,Ocirc,6l,Otilde,6m,Ouml,6n,times,6o,Oslash,6p,Ugrave,6q,Uacute,6r,Ucirc,6s,Uuml,6t,Yacute,6u,THORN,6v,szlig,70,agrave,71,aacute,72,acirc,73,atilde,74,auml,75,aring,76,aelig,77,ccedil,78,egrave,79,eacute,7a,ecirc,7b,euml,7c,igrave,7d,iacute,7e,icirc,7f,iuml,7g,eth,7h,ntilde,7i,ograve,7j,oacute,7k,ocirc,7l,otilde,7m,ouml,7n,divide,7o,oslash,7p,ugrave,7q,uacute,7r,ucirc,7s,uuml,7t,yacute,7u,thorn,7v,yuml,ci,fnof,sh,Alpha,si,Beta,sj,Gamma,sk,Delta,sl,Epsilon,sm,Zeta,sn,Eta,so,Theta,sp,Iota,sq,Kappa,sr,Lambda,ss,Mu,st,Nu,su,Xi,sv,Omicron,t0,Pi,t1,Rho,t3,Sigma,t4,Tau,t5,Upsilon,t6,Phi,t7,Chi,t8,Psi,t9,Omega,th,alpha,ti,beta,tj,gamma,tk,delta,tl,epsilon,tm,zeta,tn,eta,to,theta,tp,iota,tq,kappa,tr,lambda,ts,mu,tt,nu,tu,xi,tv,omicron,u0,pi,u1,rho,u2,sigmaf,u3,sigma,u4,tau,u5,upsilon,u6,phi,u7,chi,u8,psi,u9,omega,uh,thetasym,ui,upsih,um,piv,812,bull,816,hellip,81i,prime,81j,Prime,81u,oline,824,frasl,88o,weierp,88h,image,88s,real,892,trade,89l,alefsym,8cg,larr,8ch,uarr,8ci,rarr,8cj,darr,8ck,harr,8dl,crarr,8eg,lArr,8eh,uArr,8ei,rArr,8ej,dArr,8ek,hArr,8g0,forall,8g2,part,8g3,exist,8g5,empty,8g7,nabla,8g8,isin,8g9,notin,8gb,ni,8gf,prod,8gh,sum,8gi,minus,8gn,lowast,8gq,radic,8gt,prop,8gu,infin,8h0,ang,8h7,and,8h8,or,8h9,cap,8ha,cup,8hb,int,8hk,there4,8hs,sim,8i5,cong,8i8,asymp,8j0,ne,8j1,equiv,8j4,le,8j5,ge,8k2,sub,8k3,sup,8k4,nsub,8k6,sube,8k7,supe,8kl,oplus,8kn,otimes,8l5,perp,8m5,sdot,8o8,lceil,8o9,rceil,8oa,lfloor,8ob,rfloor,8p9,lang,8pa,rang,9ea,loz,9j0,spades,9j3,clubs,9j5,hearts,9j6,diams,ai,OElig,aj,oelig,b0,Scaron,b1,scaron,bo,Yuml,m6,circ,ms,tilde,802,ensp,803,emsp,809,thinsp,80c,zwnj,80d,zwj,80e,lrm,80f,rlm,80j,ndash,80k,mdash,80o,lsquo,80p,rsquo,80q,sbquo,80s,ldquo,80t,rdquo,80u,bdquo,810,dagger,811,Dagger,81g,permil,81p,lsaquo,81q,rsaquo,85c,euro",32),cc={strokeStyle:{svgAttr:"stroke",canvas:"#000000",svg:"none",apply:"stroke"},fillStyle:{svgAttr:"fill",canvas:"#000000",svg:null,apply:"fill"},lineCap:{svgAttr:"stroke-linecap",canvas:"butt",svg:"butt",apply:"stroke"},lineJoin:{svgAttr:"stroke-linejoin",canvas:"miter",svg:"miter",apply:"stroke"},miterLimit:{svgAttr:"stroke-miterlimit",canvas:10,svg:4,apply:"stroke"},lineWidth:{svgAttr:"stroke-width",canvas:1,svg:1,apply:"stroke"},globalAlpha:{svgAttr:"opacity",canvas:1,svg:1,apply:"fill stroke"},font:{canvas:"10px sans-serif"},shadowColor:{canvas:"#000000"},shadowOffsetX:{canvas:0},shadowOffsetY:{canvas:0},shadowBlur:{canvas:0},textAlign:{canvas:"start"},textBaseline:{canvas:"alphabetic"},lineDash:{svgAttr:"stroke-dasharray",canvas:[],svg:null,apply:"stroke"}},lc=class{__root;__ctx;constructor(t,r){this.__root=t,this.__ctx=r}addColorStop(t,r){let n=this.__ctx.__createElement("stop");if(n.setAttribute("offset",String(t)),vI(r).includes("rgba")){let i=/rgba\(\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d?\.?\d*)\s*\)/gi.exec(r);i&&(n.setAttribute("stop-color",Lr("rgb({r},{g},{b})",{r:i[1],g:i[2],b:i[3]})),n.setAttribute("stop-opacity",i[4]))}else n.setAttribute("stop-color",vI(r));this.__root.appendChild(n)}},Ep=class{__root;__ctx;constructor(t,r){this.__root=t,this.__ctx=r}},bp=class{width;height;enableMirroring;canvas;__document;__ctx;__canvas;__root;__ids;__defs;__currentElement;__styleStack;__groupStack;__currentDefaultPath;__currentPosition;__transformMatrix;__transformMatrixStack;__currentElementsToStyle;__options;__id;__fontUnderline;__fontHref;strokeStyle;fillStyle;lineCap;lineJoin;miterLimit;lineWidth;globalAlpha;font;shadowColor;shadowOffsetX;shadowOffsetY;shadowBlur;textAlign;textBaseline;lineDash;constructor(t,r){let n={width:500,height:500,enableMirroring:!1},o;typeof t=="number"&&r!==void 0?o={...n,width:t,height:r}:t&&typeof t=="object"?o=t:o=n,this.width=o.width||n.width,this.height=o.height||n.height,this.enableMirroring=o.enableMirroring!==void 0?o.enableMirroring:n.enableMirroring,this.canvas=this,this.__document=o.document||document,o.ctx?this.__ctx=o.ctx:(this.__canvas=this.__document.createElement("canvas"),this.__ctx=this.__canvas.getContext("2d")),this.__setDefaultStyles(),this.__styleStack=[this.__getStyleState()],this.__groupStack=[],this.__root=this.__document.createElementNS("http://www.w3.org/2000/svg","svg"),this.__root.setAttribute("version","1.1"),this.__root.setAttribute("xmlns","http://www.w3.org/2000/svg"),this.__root.setAttributeNS("http://www.w3.org/2000/xmlns/","xmlns:xlink","http://www.w3.org/1999/xlink"),this.__root.setAttribute("width",String(this.width)),this.__root.setAttribute("height",String(this.height)),this.__ids={},this.__defs=this.__document.createElementNS("http://www.w3.org/2000/svg","defs"),this.__root.appendChild(this.__defs),this.__currentElement=this.__document.createElementNS("http://www.w3.org/2000/svg","g"),this.__root.appendChild(this.__currentElement),this.__currentDefaultPath="",this.__currentPosition={},this.__transformMatrix=new DOMMatrix,this.resetTransform(),this.__options=o,this.__id=Math.random().toString(16).substring(2,8)}__createElement(t,r={},n){let o=this.__document.createElementNS("http://www.w3.org/2000/svg",t);n&&(o.setAttribute("fill","none"),o.setAttribute("stroke","none"));for(let i of Object.keys(r))o.setAttribute(i,r[i]);return o}__setDefaultStyles(){for(let t of Object.keys(cc))this[t]=cc[t].canvas}__applyStyleState(t){for(let r of Object.keys(t))this[r]=t[r]}__getStyleState(){let t={};for(let r of Object.keys(cc))t[r]=this[r];return t}__applyTransformation(t,r){let{a:n,b:o,c:i,d:a,e:s,f:c}=r||this.getTransform();t.setAttribute("transform",`matrix(${n} ${o} ${i} ${a} ${s} ${c})`)}__applyStyleToCurrentElement(t){let r=this.__currentElement,n=this.__currentElementsToStyle;if(n){r.setAttribute(t,""),r=n.element;for(let i of n.children)i.setAttribute(t,"")}let o=Object.keys(cc);for(let i of o){let a=cc[i],s=this[i];if(a.apply){if(s instanceof Ep){if(s.__ctx)for(let c of Array.from(s.__ctx.__defs.childNodes)){let l=c.getAttribute("id");l&&(this.__ids[l]=l,this.__defs.appendChild(c))}r.setAttribute(a.apply,Lr("url(#{id})",{id:s.__root.getAttribute("id")}))}else if(s instanceof lc)r.setAttribute(a.apply,Lr("url(#{id})",{id:s.__root.getAttribute("id")}));else if(a.apply.includes(t)&&a.svg!==s)if((a.svgAttr==="stroke"||a.svgAttr==="fill")&&s&&s.includes("rgba")){let l=/rgba\(\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d*\.?\d+)\s*,\s*(\d?\.?\d*)\s*\)/gi.exec(s);if(l){r.setAttribute(a.svgAttr,Lr("rgb({r},{g},{b})",{r:l[1],g:l[2],b:l[3]}));let u=Number(l[4]),A=this.globalAlpha;A!=null&&(u*=A),r.setAttribute(a.svgAttr+"-opacity",String(u))}}else{let c=a.svgAttr,l=s;if(i==="globalAlpha"){if(c=t+"-"+a.svgAttr,r.getAttribute(c))continue}else if(i==="lineWidth"){let u=this.__getTransformScale();l=s*Math.max(u.x,u.y)}r.setAttribute(c,l)}}}}__closestGroupOrSvg(t){return t=t||this.__currentElement,t.nodeName==="g"||t.nodeName==="svg"?t:this.__closestGroupOrSvg(t.parentNode)}getSerializedSvg(t){let r=new XMLSerializer().serializeToString(this.__root);if(/xmlns="http:\/\/www\.w3\.org\/2000\/svg".+xmlns="http:\/\/www\.w3\.org\/2000\/svg/gi.test(r)&&(r=r.replace('xmlns="http://www.w3.org/2000/svg','xmlns:xlink="http://www.w3.org/1999/xlink')),t)for(let o of Object.keys(TI)){let i=new RegExp(o,"gi");i.test(r)&&(r=r.replace(i,TI[o]))}return r}getSvg(){return this.__root}save(){let t=this.__createElement("g"),r=this.__closestGroupOrSvg();this.__groupStack.push(r),r.appendChild(t),this.__currentElement=t;let n=this.__getStyleState();this.__styleStack.push(n),this.__transformMatrixStack||(this.__transformMatrixStack=[]),this.__transformMatrixStack.push(this.getTransform())}restore(){this.__currentElement=this.__groupStack.pop(),this.__currentElementsToStyle=void 0,this.__currentElement||(this.__currentElement=this.__root.childNodes[1]);let t=this.__styleStack.pop();this.__applyStyleState(t),this.__transformMatrixStack&&this.__transformMatrixStack.length>0&&this.setTransform(this.__transformMatrixStack.pop())}beginPath(){this.__currentDefaultPath="",this.__currentPosition={};let t=this.__createElement("path",{},!0);this.__closestGroupOrSvg().appendChild(t),this.__currentElement=t}__applyCurrentDefaultPath(){let t=this.__currentElement;t.nodeName==="path"&&t.setAttribute("d",this.__currentDefaultPath)}__addPathCommand(t){this.__currentDefaultPath+=" ",this.__currentDefaultPath+=t}moveTo(t,r){this.__currentElement.nodeName!=="path"&&this.beginPath(),this.__currentPosition={x:t,y:r},this.__addPathCommand(Lr("M {x} {y}",{x:this.__matrixTransform(t,r).x,y:this.__matrixTransform(t,r).y}))}closePath(){this.__currentDefaultPath&&this.__addPathCommand("Z")}lineTo(t,r){this.__currentPosition={x:t,y:r},this.__currentDefaultPath.includes("M")?this.__addPathCommand(Lr("L {x} {y}",{x:this.__matrixTransform(t,r).x,y:this.__matrixTransform(t,r).y})):this.__addPathCommand(Lr("M {x} {y}",{x:this.__matrixTransform(t,r).x,y:this.__matrixTransform(t,r).y}))}bezierCurveTo(t,r,n,o,i,a){this.__currentPosition={x:i,y:a},this.__addPathCommand(Lr("C {cp1x} {cp1y} {cp2x} {cp2y} {x} {y}",{cp1x:this.__matrixTransform(t,r).x,cp1y:this.__matrixTransform(t,r).y,cp2x:this.__matrixTransform(n,o).x,cp2y:this.__matrixTransform(n,o).y,x:this.__matrixTransform(i,a).x,y:this.__matrixTransform(i,a).y}))}quadraticCurveTo(t,r,n,o){this.__currentPosition={x:n,y:o},this.__addPathCommand(Lr("Q {cpx} {cpy} {x} {y}",{cpx:this.__matrixTransform(t,r).x,cpy:this.__matrixTransform(t,r).y,x:this.__matrixTransform(n,o).x,y:this.__matrixTransform(n,o).y}))}stroke(){this.__currentElement.nodeName==="path"&&this.__currentElement.setAttribute("paint-order","fill stroke markers"),this.__applyCurrentDefaultPath(),this.__applyStyleToCurrentElement("stroke")}fill(){this.__currentElement.nodeName==="path"&&this.__currentElement.setAttribute("paint-order","stroke fill markers"),this.__applyCurrentDefaultPath(),this.__applyStyleToCurrentElement("fill")}rect(t,r,n,o){this.__currentElement.nodeName!=="path"&&this.beginPath(),this.moveTo(t,r),this.lineTo(t+n,r),this.lineTo(t+n,r+o),this.lineTo(t,r+o),this.lineTo(t,r),this.closePath()}__clearCanvas(){let t=this.__root.childNodes[1];this.__root.removeChild(t),this.__currentElement=this.__document.createElementNS("http://www.w3.org/2000/svg","g"),this.__root.appendChild(this.__currentElement),this.__groupStack=[]}fillRect(t,r,n,o){let{a:i,b:a,c:s,d:c,e:l,f:u}=this.getTransform();JSON.stringify([i,a,s,c,l,u])===JSON.stringify([1,0,0,1,0,0])&&t===0&&r===0&&n===this.width&&o===this.height&&this.__clearCanvas();let A=this.__createElement("rect",{x:t,y:r,width:n,height:o},!0);this.__closestGroupOrSvg().appendChild(A),this.__currentElement=A,this.__applyTransformation(A),this.__applyStyleToCurrentElement("fill")}strokeRect(t,r,n,o){let i=this.__createElement("rect",{x:t,y:r,width:n,height:o},!0);this.__closestGroupOrSvg().appendChild(i),this.__currentElement=i,this.__applyTransformation(i),this.__applyStyleToCurrentElement("stroke")}clearRect(t,r,n,o){let{a:i,b:a,c:s,d:c,e:l,f:u}=this.getTransform();if(JSON.stringify([i,a,s,c,l,u])===JSON.stringify([1,0,0,1,0,0])&&t===0&&r===0&&n===this.width&&o===this.height){this.__clearCanvas();return}let A=this.__createElement("rect",{x:t,y:r,width:n,height:o,fill:"#FFFFFF"},!0);this.__applyTransformation(A),this.__closestGroupOrSvg().appendChild(A)}createLinearGradient(t,r,n,o){let i=this.__createElement("linearGradient",{id:xp(this.__ids),x1:t+"px",x2:n+"px",y1:r+"px",y2:o+"px",gradientUnits:"userSpaceOnUse"});return this.__defs.appendChild(i),new lc(i,this)}createRadialGradient(t,r,n,o,i,a){let s=this.__createElement("radialGradient",{id:xp(this.__ids),cx:o+"px",cy:i+"px",r:a+"px",fx:t+"px",fy:r+"px",gradientUnits:"userSpaceOnUse"});return this.__defs.appendChild(s),new lc(s,this)}__applyText(t,r,n,o){let i=document.createElement("span");i.setAttribute("style","font:"+this.font);let a=i.style,s=this.__closestGroupOrSvg(),c=this.__createElement("text",{"font-family":a.fontFamily,"font-size":a.fontSize,"font-style":a.fontStyle,"font-weight":a.fontWeight,"text-decoration":this.__fontUnderline,x:r,y:n,"text-anchor":K3(this.textAlign),"dominant-baseline":X3(this.textBaseline)},!0);c.appendChild(this.__document.createTextNode(t)),this.__currentElement=c,this.__applyTransformation(c),this.__applyStyleToCurrentElement(o);let l=c;if(this.__fontHref){let u=this.__createElement("a");u.setAttributeNS("http://www.w3.org/1999/xlink","xlink:href",this.__fontHref),u.appendChild(c),l=u}s.appendChild(l)}fillText(t,r,n){this.__applyText(t,r,n,"fill")}strokeText(t,r,n){this.__applyText(t,r,n,"stroke")}measureText(t){return this.__ctx.font=this.font,this.__ctx.measureText(t)}arc(t,r,n,o,i,a){if(o===i)return;o=o%(2*Math.PI),i=i%(2*Math.PI),o===i&&(i=(i+2*Math.PI-.001*(a?-1:1))%(2*Math.PI));let s=t+n*Math.cos(i),c=r+n*Math.sin(i),l=t+n*Math.cos(o),u=r+n*Math.sin(o),A=a?0:1,m=0,f=i-o;f<0&&(f+=2*Math.PI),a?m=f>Math.PI?0:1:m=f>Math.PI?1:0;let g=Math.hypot(this.__transformMatrix.a,this.__transformMatrix.b),y=Math.hypot(this.__transformMatrix.c,this.__transformMatrix.d);this.lineTo(l,u),this.__addPathCommand(Lr("A {rx} {ry} {xAxisRotation} {largeArcFlag} {sweepFlag} {endX} {endY}",{rx:n*g,ry:n*y,xAxisRotation:0,largeArcFlag:m,sweepFlag:A,endX:this.__matrixTransform(s,c).x,endY:this.__matrixTransform(s,c).y})),this.__currentPosition={x:s,y:c}}clip(){let t=this.__closestGroupOrSvg(),r=this.__createElement("clipPath"),n=xp(this.__ids),o=this.__createElement("g");this.__applyCurrentDefaultPath(),t.removeChild(this.__currentElement),r.setAttribute("id",n),r.appendChild(this.__currentElement),this.__defs.appendChild(r),t.setAttribute("clip-path",Lr("url(#{id})",{id:n})),t.appendChild(o),this.__currentElement=o}setLineDash(t){t&&t.length>0?this.lineDash=t.join(","):this.lineDash=null}setTransform(t,r,n,o,i,a){t instanceof DOMMatrix?this.__transformMatrix=new DOMMatrix([t.a,t.b,t.c,t.d,t.e,t.f]):this.__transformMatrix=new DOMMatrix([t,r,n,o,i,a])}getTransform(){let{a:t,b:r,c:n,d:o,e:i,f:a}=this.__transformMatrix;return new DOMMatrix([t,r,n,o,i,a])}resetTransform(){this.setTransform(1,0,0,1,0,0)}scale(t,r){if(r===void 0&&(r=t),isNaN(t)||isNaN(r)||!isFinite(t)||!isFinite(r))return;let n=this.getTransform().scale(t,r);this.setTransform(n)}rotate(t){let r=this.getTransform().multiply(new DOMMatrix([Math.cos(t),Math.sin(t),-Math.sin(t),Math.cos(t),0,0]));this.setTransform(r)}translate(t,r){let n=this.getTransform().translate(t,r);this.setTransform(n)}transform(t,r,n,o,i,a){let s=this.getTransform().multiply(new DOMMatrix([t,r,n,o,i,a]));this.setTransform(s)}__matrixTransform(t,r){return new DOMPoint(t,r).matrixTransform(this.__transformMatrix)}__getTransformScale(){return{x:Math.hypot(this.__transformMatrix.a,this.__transformMatrix.b),y:Math.hypot(this.__transformMatrix.c,this.__transformMatrix.d)}}__getTransformRotation(){return Math.atan2(this.__transformMatrix.b,this.__transformMatrix.a)}drawFocusRing(){}createImageData(){}putImageData(){}globalCompositeOperation(){}drawImage(){}createPattern(){return null}}});var RI={};bt(RI,{renderToSvg:()=>NI});function tO(e){let t=e.visibleDomainTypes.map(o=>o.name),r=Math.max(0,...t.map(o=>o.length)),n=uc*2+fc+6+r*eO;return Math.min(360,Math.max(120,n))}function rO(e,t){let{width:r,height:n,scrollX:o,scrollY:i,totalWidth:a,totalHeight:s,treeAreaWidth:c,totalTrackAreaHeight:l,minimapHeight:u}=e,A=t.includeTracks?l:0,m=t.exportType==="viewport"&&!!t.includeMinimap,f=e.actuallyShowDomains&&e.visibleDomainTypes.length>0?tO(e):0;return t.exportType==="entire"?{width:a+c,height:s+A,contentHeight:s,trackHeight:A,offsetX:0,offsetY:0,includeMinimap:m,legendWidth:f}:{width:r,height:n+(m?u:0)+A,contentHeight:n,trackHeight:A,offsetX:-o,offsetY:-i,includeMinimap:m,legendWidth:f}}async function NI(e,t){await(0,DI.when)(()=>e.dataInitialized);let{Context:r}=await Promise.resolve().then(()=>(MI(),QI));return(0,kI.renderToStaticMarkup)(re.default.createElement(nO,{model:e,theme:t.theme,Context:r,layout:rO(e,t)}))}function nO({model:e,theme:t,Context:r,layout:n}){let{width:o,height:i,trackHeight:a,includeMinimap:s,legendWidth:c}=n,{treeAreaWidth:l,minimapHeight:u}=e,A=o+c,m=s?u:0,f=re.default.createElement(re.default.Fragment,null,a>0?re.default.createElement(aO,{Context:r,model:e,theme:t,layout:n}):null,re.default.createElement("g",{transform:a>0?`translate(0 ${a})`:void 0},re.default.createElement(iO,{Context:r,model:e,theme:t,layout:n})));return re.default.createElement("svg",{width:A,height:i,xmlns:"http://www.w3.org/2000/svg",xmlnsXlink:"http://www.w3.org/1999/xlink",viewBox:`0 0 ${A} ${i}`},re.default.createElement("rect",{width:"100%",height:"100%",fill:"white"}),s?re.default.createElement(re.default.Fragment,null,re.default.createElement("g",{transform:`translate(${l} 0)`},re.default.createElement(Gb,{model:e})),re.default.createElement("g",{transform:`translate(0 ${u})`},f)):f,c>0?re.default.createElement("g",{transform:`translate(${o} ${m})`},re.default.createElement(oO,{model:e,width:c})):null)}function oO({model:e,width:t}){let{visibleDomainTypes:r,fillPalette:n,strokePalette:o}=e,i=uc*2+r.length*_I;return re.default.createElement("g",null,re.default.createElement("rect",{x:0,y:0,width:t-4,height:i,fill:"white",stroke:"#ccc",rx:2}),r.map((a,s)=>{let c=uc+s*_I;return re.default.createElement("g",{key:a.accession},re.default.createElement("rect",{x:uc,y:c,width:fc,height:fc,fill:n[a.accession],stroke:o[a.accession]}),re.default.createElement("text",{x:uc+fc+6,y:c+fc-1,fontSize:Z3},a.name))}))}function iO({model:e,theme:t,layout:r,Context:n}){let{contentHeight:o,offsetX:i,offsetY:a,width:s}=r,{treeAreaWidth:c,colorScheme:l,id:u}=e,A=s-c,m=nc(l,t),f=new n(c,o);Ru({model:e,theme:t,ctx:f,offsetY:a,blockSizeYOverride:o,highResScaleFactorOverride:1});let g=new n(A,o);return Bu({model:e,ctx:g,offsetX:i,offsetY:a,blockSizeYOverride:o,highResScaleFactorOverride:1}),_u({model:e,theme:t,ctx:g,contrastScheme:m,offsetX:i,offsetY:a,blockSizeXOverride:A,blockSizeYOverride:o,highResScaleFactorOverride:1}),re.default.createElement(re.default.Fragment,null,re.default.createElement(Ip,{clipId:`tree-${u}`,width:c,height:o,ctx:f}),re.default.createElement(Ip,{clipId:`msa-${u}`,width:A,height:o,transform:`translate(${c} 0)`,ctx:g}))}function aO({model:e,theme:t,layout:r,Context:n}){let{trackHeight:o,offsetX:i,width:a}=r,{treeAreaWidth:s,colorScheme:c,id:l}=e,u=a-s,A=nc(c,t),m=new n(u,o);return pI({model:e,ctx:m,contrastScheme:A,offsetX:i,blockSizeXOverride:u,highResScaleFactorOverride:1}),re.default.createElement("g",{transform:`translate(${s} 0)`},re.default.createElement(Ip,{clipId:`tracks-${l}`,width:u,height:o,ctx:m}))}function Ip({clipId:e,width:t,height:r,transform:n,ctx:o}){return re.default.createElement(re.default.Fragment,null,re.default.createElement("defs",null,re.default.createElement("clipPath",{id:e},re.default.createElement("rect",{x:0,y:0,width:t,height:r}))),re.default.createElement("g",{clipPath:`url(#${e})`,transform:n,dangerouslySetInnerHTML:{__html:o.getSvg().innerHTML}}))}var re,kI,DI,uc,_I,fc,Z3,eO,wp=d(()=>{re=p(k(),1),kI=p(Be(),1),DI=p(Ca(),1);Ub();ep();Ap();ku();Lu();so();uc=8,_I=16,fc=12,Z3=12,eO=7});var Ye=z((RK,LI)=>{LI.exports=JBrowseExports["@jbrowse/core/ui"]});var FI,PI,Ia,Sp=d(()=>{FI=p(O(),1),PI=p(k(),1),Ia=class extends PI.Component{constructor(t){super(t),this.state={error:void 0}}componentDidCatch(t,r){console.error("ErrorBoundary caught an error:",t,r),this.setState({error:t})}render(){return this.state.error?(0,FI.jsx)(this.props.FallbackComponent,{error:this.state.error}):this.props.children}}});var V=z((FK,OI)=>{OI.exports=JBrowseExports["@mui/material"]});function co(e,t){let r=(0,wa.useRef)(!1),[n,o]=(0,wa.useState)();return(0,wa.useEffect)(()=>{if(n!==void 0){let s=function(l){r.current||(r.current=!0,requestAnimationFrame(()=>{let u=e==="x"?l.clientX:l.clientY;t(u-i,a),r.current=!1}))},c=function(){o(void 0)},{client:i,startScroll:a}=n;return document.addEventListener("mousemove",s),document.addEventListener("mouseup",c),()=>{document.removeEventListener("mousemove",s),document.removeEventListener("mouseup",c)}}},[e,t,n]),{dragging:n!==void 0,startDrag:(i,a)=>{o({client:e==="x"?i.clientX:i.clientY,startScroll:a})}}}var wa,Fu=d(()=>{wa=p(k(),1)});var Cr,Pu,Bp,vp,GI,UI,HI,Tp=d(()=>{Cr=p(k(),1),Pu=p($(),1);Fu();Bp="rgba(200,200,200)",vp="rgba(150,150,150)",GI=(0,Pu.observer)(function({model:e}){let{resizeHandleWidth:t}=e,[r,n]=(0,Cr.useState)(!1),{startDrag:o}=co("x",(0,Cr.useCallback)((i,a)=>{e.setTreeAreaWidth(a+i)},[e]));return Cr.default.createElement("div",{onMouseDown:i=>{o(i,e.treeAreaWidth)},onMouseEnter:()=>{n(!0)},onMouseLeave:()=>{n(!1)},style:{cursor:"ew-resize",width:t,background:r?vp:Bp,position:"relative"}})}),UI=(0,Pu.observer)(function({model:e}){let{resizeHandleWidth:t}=e,[r,n]=(0,Cr.useState)(!1),{startDrag:o}=co("y",(0,Cr.useCallback)((i,a)=>{e.setHeight(a+i)},[e]));return Cr.default.createElement("div",{onMouseDown:i=>{o(i,e.height)},onMouseEnter:()=>{n(!0)},onMouseLeave:()=>{n(!1)},style:{cursor:"ns-resize",width:"100%",height:t,background:r?vp:Bp,position:"relative"}})}),HI=(0,Pu.observer)(function({model:e}){let{resizeHandleWidth:t}=e,[r,n]=(0,Cr.useState)(!1),{startDrag:o}=co("y",(0,Cr.useCallback)((i,a)=>{e.setConservationTrackHeight(Math.max(10,a+i))},[e]));return Cr.default.createElement("div",{onMouseDown:i=>{o(i,e.conservationTrackHeight)},onMouseEnter:()=>{n(!0)},onMouseLeave:()=>{n(!1)},style:{position:"absolute",bottom:0,left:0,cursor:"ns-resize",width:"100%",height:t,zIndex:1,background:r?vp:Bp}})})});var Qp=z((UK,VI)=>{VI.exports=JBrowseExports["@mui/material/styles"]});var Sa,Mp=d(()=>{Sa=e=>{let t=e.length,r=0,n="";for(;r<t;r++){let o=e[r];if(o==null)continue;let i;switch(typeof o){case"boolean":break;case"object":{if(Array.isArray(o))i=Sa(o);else{let a=o;i="";for(let s in a)a[s]&&s&&(i&&(i+=" "),i+=s)}break}default:i=o}i&&(n&&(n+=" "),n+=i)}return n}});function jI(e){return e instanceof Object&&!("styles"in e)&&!("length"in e)&&!("__emotion_styles"in e)}var YI=d(()=>{});function JI(e){let{useCache:t}=e;function r(){let n=t(),{css:o,cx:i}=(0,qI.useMemo)(()=>sO({cache:n}),[n]);return{css:o,cx:i}}return{useCssAndCx:r}}var qI,sO,$I,WI=d(()=>{qI=p(k(),1);Yo();ca();Mp();YI();({createCssAndCx:sO}=(()=>{function e(r,n,o){let i=[],a=Vo(r,i,o);return i.length<2?o:a+n(i)}function t(r){let{cache:n}=r,o=(...a)=>{let s=an(a,n.registered);jo(n,s,!1);let c=`${n.key}-${s.name}`;e:{let l=a[0];if(!jI(l))break e;$I.saveClassNameCSSObjectMapping(n,c,l)}return c};return{css:o,cx:(...a)=>{let s=Sa(a),c=$I.fixClassName(n,s,o);return e(n.registered,o,c)}}}return{createCssAndCx:t}})());$I=(()=>{let e=new WeakMap;return{saveClassNameCSSObjectMapping:(t,r,n)=>{let o=e.get(t);o===void 0&&(o=new Map,e.set(t,o)),o.set(r,n)},fixClassName:(()=>{function t(r){let n=!1;return r.map(([o,i])=>{if(i===void 0)return o;let a;if(n)a={"&&":i};else{a=o;for(let s in i)if(s.startsWith("@media")){n=!0;break}}return a})}return(r,n,o)=>{if(!n.includes(" "))return n;let i=e.get(r);return Sa(t(n.split(" ").map(a=>[a,i?.get(a)])).map(a=>typeof a=="string"?a:o(a)))}})()}})()});function zI(e,t,r){if(!(t instanceof Object))return e;let n=Object.keys(t);if(n.length===0)return e;let o={};for(let i of Object.keys(e))o[i]=r(e[i],t[i]);for(let i of n){if(i in e)continue;let a=t[i];typeof a=="string"&&(o[i]=a)}return o}var KI=d(()=>{});function XI(e){if(!(e instanceof Object)||typeof e=="function")return e;let t=[];for(let r in e){let n=e[r],o=typeof n;if(!(o==="string"||o==="number"&&!isNaN(n)||o==="boolean"||n===void 0||n===null))return e;t.push(`${r}:${o}_${n}`)}return`xSqLiJdLMd9s${t.join("|")}`}var ZI=d(()=>{});function ew(e){let{useTheme:t}=e,{useCssAndCx:r}=JI({useCache:cO});function n(){return function(o){let i=typeof o=="function"?o:()=>o;return function(s,c){let l=t(),{css:u,cx:A}=r(),m=(0,_p.useMemo)(()=>{let E=i(l),b={};for(let x of Object.keys(E)){let B=E[x];b[x]=u(B)}return b},[u,l]),f=c?.props.classes,g=XI(f);return{classes:(0,_p.useMemo)(()=>f?zI(m,f,A):m,[m,g,A]),theme:l,css:u,cx:A}}}}return{makeStyles:n}}var _p,cO,tw=d(()=>{"use client";_p=p(k(),1);Hs();WI();KI();ZI();cO=rm});var rw,X,nw=d(()=>{rw=p(Qp(),1);tw();({makeStyles:X}=ew({useTheme:rw.useTheme}))});var ow=d(()=>{nw()});function Ou(...e){return Sa(e)}var $e=d(()=>{"use client";Hs();ow();Mp()});var iw,aw,sw=d(()=>{"use client";Ee();iw=p(O(),1),aw=Y((0,iw.jsx)("path",{d:"m7 10 5 5 5-5z"}),"ArrowDropDown")});function cw(e,t){return t===1?e*16:t===2?e*100:e}function lw(e){let t=Math.abs(e);return t<6?25:t>150?500:t>30?150:75}function uw(e,t){let r=lO*t,n=Math.max(-r,Math.min(r,e));return n>0?1/(1+n):1-n}var lO,fw=d(()=>{lO=.011997600479904018});function Ba({ref:e,onScrollX:t,onScrollY:r,onZoom:n,scrollZoom:o}){let i=(0,It.useRef)(!1),a=(0,It.useRef)(!1),s=(0,It.useRef)(0),c=(0,It.useRef)(0),l=(0,It.useRef)(0),u=(0,It.useRef)(0),A=(0,It.useRef)(0),m=(0,It.useRef)(null),f=(0,It.useRef)(0),g=(0,It.useRef)(0),[y,E]=(0,It.useState)(!1);(0,It.useEffect)(()=>{let B=e.current;if(!B)return;function I(w){let S=w.ctrlKey||w.metaKey,v=o&&!w.shiftKey&&Math.abs(w.deltaY)>=Math.abs(w.deltaX);if(n&&(S||v)){let L=B.getBoundingClientRect(),P=cw(w.deltaY,w.deltaMode),h=S?lw(P):500;l.current+=P/h,u.current=w.clientX-L.left,A.current=w.clientY-L.top,a.current||(a.current=!0,requestAnimationFrame(Q=>{let _=m.current===null?16.67:Q-m.current;m.current=Q,n(uw(l.current,Math.min(100,_)),u.current,A.current),l.current=0,a.current=!1})),w.preventDefault(),w.stopPropagation();return}let D=!!t&&w.deltaX!==0,N=!!r&&w.deltaY!==0;(D||N)&&(t&&(s.current+=w.deltaX),r&&(c.current+=w.deltaY),i.current||(i.current=!0,requestAnimationFrame(()=>{t&&(t(-s.current),s.current=0),r&&(r(-c.current),c.current=0),i.current=!1})),w.preventDefault(),w.stopPropagation())}return B.addEventListener("wheel",I,{passive:!1}),()=>{B.removeEventListener("wheel",I)}},[e,t,r,n,o]),(0,It.useEffect)(()=>{if(!y)return;function B(w){w.preventDefault();let S=w.clientX-f.current,v=w.clientY-g.current;(S&&t||v&&r)&&(i.current||(i.current=!0,requestAnimationFrame(()=>{t?.(S),r?.(v),i.current=!1,f.current=w.clientX,g.current=w.clientY})))}function I(){f.current=0,g.current=0,E(!1)}return window.addEventListener("mousemove",B,!0),window.addEventListener("mouseup",I,!0),()=>{window.removeEventListener("mousemove",B,!0),window.removeEventListener("mouseup",I,!0)}},[y,t,r]);function b(B){let I=B.target;I.draggable||I.dataset.resizer||B.button===0&&(f.current=B.clientX,g.current=B.clientY,E(!0))}function x(B){B.preventDefault(),E(!1)}return{onMouseDown:b,onMouseUp:x}}var It,Gu=d(()=>{It=p(k(),1);fw()});function Ac(e){let t=navigator.clipboard;if(t?.writeText){t.writeText(e).catch(n=>{console.error("Failed to copy to clipboard:",n)});return}let r=document.createElement("textarea");r.value=e,r.style.position="fixed",r.style.opacity="0",document.body.append(r),r.select(),document.execCommand("copy"),r.remove()}var kp=d(()=>{});var mw={};bt(mw,{default:()=>dO});var Ln,Aw,ri,dw,fO,AO,dO,pw=d(()=>{Ln=p(k(),1),Aw=p(Ye(),1);$e();ri=p(V(),1),dw=p($(),1);kp();fO=X()(e=>({textArea:{padding:e.spacing(2),overflow:"auto",background:"#ddd",wordBreak:"break-word"}})),AO=(0,dw.observer)(function({model:e,onClose:t}){let[r,n]=(0,Ln.useState)("Copy to clipboard"),{classes:o}=fO();return Ln.default.createElement(Aw.Dialog,{open:!0,onClose:t,fullWidth:!0,maxWidth:"lg",title:`Track info - ${e.name}`},Ln.default.createElement(ri.DialogContent,null,Ln.default.createElement(ri.Button,{variant:"contained",color:"primary",onClick:()=>{Ac(e.data),n("Copied!"),setTimeout(()=>{n("Copy to clipboard")},300)}},r),Ln.default.createElement("pre",{className:o.textArea},e.data)),Ln.default.createElement(ri.DialogActions,null,Ln.default.createElement(ri.Button,{variant:"contained",onClick:t,color:"secondary"},"Close")))}),dO=AO});var Ke,ni,Dp,mO,pO,gO,hO,gw,hw=d(()=>{Ke=p(k(),1);$e();sw();ni=p(V(),1),Dp=p($(),1);Gu();mO=(0,Ke.lazy)(()=>Promise.resolve().then(()=>(pw(),mw))),pO=X()({button:{padding:0}}),gO=(0,Dp.observer)(function({model:t,track:r}){let[n,o]=(0,Ke.useState)(),i=()=>{o(void 0)},{drawLabels:a,fontSize:s,treeAreaWidth:c}=t,{model:{name:l,height:u}}=r,{classes:A}=pO(),m=Math.min(u,s);return Ke.default.createElement("div",{style:{width:c,height:u,flexShrink:0,textAlign:"right",fontSize:m}},a?l:""," ",Ke.default.createElement(ni.IconButton,{className:A.button,style:{width:m,height:m},onClick:f=>{o(f.currentTarget)}},Ke.default.createElement(aw,null)),n?Ke.default.createElement(ni.Menu,{anchorEl:n,transitionDuration:0,open:!0,onClose:()=>{i()}},Ke.default.createElement(ni.MenuItem,{dense:!0,onClick:()=>{t.toggleTrack(r.model.id),i()}},"Close"),Ke.default.createElement(ni.MenuItem,{dense:!0,onClick:()=>{t.queueDialog(f=>[mO,{onClose:f,model:r.model}]),i()}},"Get info")):null)}),hO=(0,Dp.observer)(function({model:e,track:t}){let{resizeHandleWidth:r,colWidth:n,scrollX:o,numColumns:i}=e,{model:{height:a}}=t,s=(0,Ke.useRef)(null),c=(0,Ke.useCallback)(l=>{e.doScrollX(l)},[e]);return Ba({ref:s,onScrollX:c}),Ke.default.createElement("div",{style:{display:"flex",height:a}},Ke.default.createElement(gO,{model:e,track:t}),Ke.default.createElement("div",{style:{width:r,flexShrink:0}}),Ke.default.createElement("div",{ref:s,onMouseMove:l=>{if(!s.current)return;let{left:u}=s.current.getBoundingClientRect(),A=l.clientX-u-o,m=Math.floor(A/n);m>=0&&m<i?e.setMousePos(m,void 0):e.setMousePos(void 0,void 0)},onMouseLeave:()=>{e.setMousePos(void 0,void 0)}},Ke.default.createElement(t.ReactComponent,{model:e,track:t})))}),gw=hO});var oi,Cw,yw,CO,xw,Ew=d(()=>{oi=p(k(),1),Cw=p(Be(),1),yw=p($(),1);Fu();CO=(0,yw.observer)(({model:e})=>{let{msaAreaHeight:t,scrollY:r,totalHeight:n}=e,[o,i]=(0,oi.useState)(!1),a="rgba(66, 119, 127, 0.3)",s=t/n,c=-r,l=c+t,u=c*s,A=l*s,{startDrag:m}=co("y",(0,oi.useCallback)((f,g)=>{e.setScrollY((0,Cw.clamp)(g-f/s,e.maxScrollY,0))},[e,s]));return oi.default.createElement("div",{style:{position:"relative",width:20,height:t,borderLeft:"1px solid #555",borderTop:"1px solid #555",boxSizing:"border-box"}},oi.default.createElement("div",{style:{position:"absolute",top:Math.max(0,u),left:0,background:o?"rgba(66,119,127,0.6)":a,cursor:"pointer",boxSizing:"border-box",width:20,height:Math.max(A-u,20),zIndex:100},onMouseOver:()=>{i(!0)},onMouseOut:()=>{i(!1)},onMouseDown:f=>{m(f,e.scrollY)}}))}),xw=CO});function Np(){let e=(0,va.useRef)(null),[t,r]=(0,va.useState)({width:void 0,height:void 0});return(0,va.useEffect)(()=>{if(!e.current)return;let n=typeof window<"u"&&"ResizeObserver"in window?window.ResizeObserver:void 0;if(!n)return;let o=new n(i=>{r({width:i[0].contentRect.width,height:i[0].contentRect.height})});return o.observe(e.current),()=>{o.disconnect()}},[]),[e,t]}var va,bw=d(()=>{va=p(k(),1)});var Iw,ww,Sw=d(()=>{"use client";Ee();Iw=p(O(),1),ww=Y((0,Iw.jsx)("path",{d:"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m1 17h-2v-2h2zm2.07-7.75-.9.92C13.45 12.9 13 13.5 13 15h-2v-.5c0-1.1.45-2.1 1.17-2.83l1.24-1.26c.37-.36.59-.86.59-1.41 0-1.1-.9-2-2-2s-2 .9-2 2H8c0-2.21 1.79-4 4-4s4 1.79 4 4c0 .88-.36 1.68-.93 2.25"}),"Help")});var vw=z((vX,Bw)=>{Bw.exports=JBrowseExports["@mui/material/utils"]});var ve,Xt=d(()=>{"use client";ve=p(vw(),1)});var Tw,Qw,Mw=d(()=>{"use client";Xt();Tw=p(O(),1),Qw=(0,ve.createSvgIcon)((0,Tw.jsx)("path",{d:"M10 6 8.59 7.41 13.17 12l-4.58 4.59L10 18l6-6z"}),"ChevronRight")});var _w,kw,Dw=d(()=>{"use client";Xt();_w=p(O(),1),kw=(0,ve.createSvgIcon)((0,_w.jsx)("path",{d:"M11 18h2v-2h-2zm1-16C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m0 18c-4.41 0-8-3.59-8-8s3.59-8 8-8 8 3.59 8 8-3.59 8-8 8m0-14c-2.21 0-4 1.79-4 4h2c0-1.1.9-2 2-2s2 .9 2 2c0 2-3 1.75-3 5h2c0-2.25 3-2.5 3-5 0-2.21-1.79-4-4-4"}),"HelpOutline")});var Nw,Uu,Rp=d(()=>{"use client";Xt();Nw=p(O(),1),Uu=(0,ve.createSvgIcon)((0,Nw.jsx)("path",{d:"M19 6.41 17.59 5 12 10.59 6.41 5 5 6.41 10.59 12 5 17.59 6.41 19 12 13.41 17.59 19 19 17.59 13.41 12z"}),"Close")});var Rw,Lw,Fw=d(()=>{"use client";Xt();Rw=p(O(),1),Lw=(0,ve.createSvgIcon)((0,Rw.jsx)("path",{d:"M17.65 6.35C16.2 4.9 14.21 4 12 4c-4.42 0-7.99 3.58-7.99 8s3.57 8 7.99 8c3.73 0 6.84-2.55 7.73-6h-2.08c-.82 2.33-3.04 4-5.65 4-3.31 0-6-2.69-6-6s2.69-6 6-6c1.66 0 3.14.69 4.22 1.78L13 11h7V4z"}),"Refresh")});var Pw,Ow,Gw=d(()=>{"use client";Xt();Pw=p(O(),1),Ow=(0,ve.createSvgIcon)((0,Pw.jsx)("path",{d:"M15.73 3H8.27L3 8.27v7.46L8.27 21h7.46L21 15.73V8.27zM12 17.3c-.72 0-1.3-.58-1.3-1.3s.58-1.3 1.3-1.3 1.3.58 1.3 1.3-.58 1.3-1.3 1.3m1-4.3h-2V7h2z"}),"Report")});function Lp({children:e}){let{classes:t}=yO();return(0,Uw.jsx)("div",{className:t.bg,children:e})}var Uw,yO,Hw=d(()=>{Uw=p(O(),1);$e();yO=X()(e=>({bg:{padding:4,margin:4,overflow:"auto",maxHeight:200,background:e.palette.mode==="dark"?"#833":"#f88",border:`1px solid ${e.palette.divider}`}}))});var jw=z(Fp=>{var Vw="ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/".split("");Fp.encode=function(e){if(0<=e&&e<Vw.length)return Vw[e];throw new TypeError("Must be between 0 and 63: "+e)};Fp.decode=function(e){var t=65,r=90,n=97,o=122,i=48,a=57,s=43,c=47,l=26,u=52;return t<=e&&e<=r?e-t:n<=e&&e<=o?e-n+l:i<=e&&e<=a?e-i+u:e==s?62:e==c?63:-1}});var Gp=z(Op=>{var Yw=jw(),Pp=5,$w=1<<Pp,qw=$w-1,Jw=$w;function xO(e){return e<0?(-e<<1)+1:(e<<1)+0}function EO(e){var t=(e&1)===1,r=e>>1;return t?-r:r}Op.encode=function(t){var r="",n,o=xO(t);do n=o&qw,o>>>=Pp,o>0&&(n|=Jw),r+=Yw.encode(n);while(o>0);return r};Op.decode=function(t,r,n){var o=t.length,i=0,a=0,s,c;do{if(r>=o)throw new Error("Expected more digits in base 64 VLQ value.");if(c=Yw.decode(t.charCodeAt(r++)),c===-1)throw new Error("Invalid base64 digit: "+t.charAt(r-1));s=!!(c&Jw),c&=qw,i=i+(c<<a),a+=Pp}while(s);n.value=EO(i),n.rest=r}});var Qa=z(st=>{function bO(e,t,r){if(t in e)return e[t];if(arguments.length===3)return r;throw new Error('"'+t+'" is a required argument.')}st.getArg=bO;var Ww=/^(?:([\w+\-.]+):)?\/\/(?:(\w+:\w+)@)?([\w.-]*)(?::(\d+))?(.*)$/,IO=/^data:.+\,.+$/;function dc(e){var t=e.match(Ww);return t?{scheme:t[1],auth:t[2],host:t[3],port:t[4],path:t[5]}:null}st.urlParse=dc;function Ta(e){var t="";return e.scheme&&(t+=e.scheme+":"),t+="//",e.auth&&(t+=e.auth+"@"),e.host&&(t+=e.host),e.port&&(t+=":"+e.port),e.path&&(t+=e.path),t}st.urlGenerate=Ta;var wO=32;function SO(e){var t=[];return function(r){for(var n=0;n<t.length;n++)if(t[n].input===r){var o=t[0];return t[0]=t[n],t[n]=o,t[0].result}var i=e(r);return t.unshift({input:r,result:i}),t.length>wO&&t.pop(),i}}var Up=SO(function(t){var r=t,n=dc(t);if(n){if(!n.path)return t;r=n.path}for(var o=st.isAbsolute(r),i=[],a=0,s=0;;)if(a=s,s=r.indexOf("/",a),s===-1){i.push(r.slice(a));break}else for(i.push(r.slice(a,s));s<r.length&&r[s]==="/";)s++;for(var c,l=0,s=i.length-1;s>=0;s--)c=i[s],c==="."?i.splice(s,1):c===".."?l++:l>0&&(c===""?(i.splice(s+1,l),l=0):(i.splice(s,2),l--));return r=i.join("/"),r===""&&(r=o?"/":"."),n?(n.path=r,Ta(n)):r});st.normalize=Up;function zw(e,t){e===""&&(e="."),t===""&&(t=".");var r=dc(t),n=dc(e);if(n&&(e=n.path||"/"),r&&!r.scheme)return n&&(r.scheme=n.scheme),Ta(r);if(r||t.match(IO))return t;if(n&&!n.host&&!n.path)return n.host=t,Ta(n);var o=t.charAt(0)==="/"?t:Up(e.replace(/\/+$/,"")+"/"+t);return n?(n.path=o,Ta(n)):o}st.join=zw;st.isAbsolute=function(e){return e.charAt(0)==="/"||Ww.test(e)};function BO(e,t){e===""&&(e="."),e=e.replace(/\/$/,"");for(var r=0;t.indexOf(e+"/")!==0;){var n=e.lastIndexOf("/");if(n<0||(e=e.slice(0,n),e.match(/^([^\/]+:\/)?\/*$/)))return t;++r}return Array(r+1).join("../")+t.substr(e.length+1)}st.relative=BO;var Kw=(function(){var e=Object.create(null);return!("__proto__"in e)})();function Xw(e){return e}function vO(e){return Zw(e)?"$"+e:e}st.toSetString=Kw?Xw:vO;function TO(e){return Zw(e)?e.slice(1):e}st.fromSetString=Kw?Xw:TO;function Zw(e){if(!e)return!1;var t=e.length;if(t<9||e.charCodeAt(t-1)!==95||e.charCodeAt(t-2)!==95||e.charCodeAt(t-3)!==111||e.charCodeAt(t-4)!==116||e.charCodeAt(t-5)!==111||e.charCodeAt(t-6)!==114||e.charCodeAt(t-7)!==112||e.charCodeAt(t-8)!==95||e.charCodeAt(t-9)!==95)return!1;for(var r=t-10;r>=0;r--)if(e.charCodeAt(r)!==36)return!1;return!0}function QO(e,t,r){var n=Fn(e.source,t.source);return n!==0||(n=e.originalLine-t.originalLine,n!==0)||(n=e.originalColumn-t.originalColumn,n!==0||r)||(n=e.generatedColumn-t.generatedColumn,n!==0)||(n=e.generatedLine-t.generatedLine,n!==0)?n:Fn(e.name,t.name)}st.compareByOriginalPositions=QO;function MO(e,t,r){var n;return n=e.originalLine-t.originalLine,n!==0||(n=e.originalColumn-t.originalColumn,n!==0||r)||(n=e.generatedColumn-t.generatedColumn,n!==0)||(n=e.generatedLine-t.generatedLine,n!==0)?n:Fn(e.name,t.name)}st.compareByOriginalPositionsNoSource=MO;function _O(e,t,r){var n=e.generatedLine-t.generatedLine;return n!==0||(n=e.generatedColumn-t.generatedColumn,n!==0||r)||(n=Fn(e.source,t.source),n!==0)||(n=e.originalLine-t.originalLine,n!==0)||(n=e.originalColumn-t.originalColumn,n!==0)?n:Fn(e.name,t.name)}st.compareByGeneratedPositionsDeflated=_O;function kO(e,t,r){var n=e.generatedColumn-t.generatedColumn;return n!==0||r||(n=Fn(e.source,t.source),n!==0)||(n=e.originalLine-t.originalLine,n!==0)||(n=e.originalColumn-t.originalColumn,n!==0)?n:Fn(e.name,t.name)}st.compareByGeneratedPositionsDeflatedNoLine=kO;function Fn(e,t){return e===t?0:e===null?1:t===null?-1:e>t?1:-1}function DO(e,t){var r=e.generatedLine-t.generatedLine;return r!==0||(r=e.generatedColumn-t.generatedColumn,r!==0)||(r=Fn(e.source,t.source),r!==0)||(r=e.originalLine-t.originalLine,r!==0)||(r=e.originalColumn-t.originalColumn,r!==0)?r:Fn(e.name,t.name)}st.compareByGeneratedPositionsInflated=DO;function NO(e){return JSON.parse(e.replace(/^\)]}'[^\n]*\n/,""))}st.parseSourceMapInput=NO;function RO(e,t,r){if(t=t||"",e&&(e[e.length-1]!=="/"&&t[0]!=="/"&&(e+="/"),t=e+t),r){var n=dc(r);if(!n)throw new Error("sourceMapURL could not be parsed");if(n.path){var o=n.path.lastIndexOf("/");o>=0&&(n.path=n.path.substring(0,o+1))}t=zw(Ta(n),t)}return Up(t)}st.computeSourceURL=RO});var jp=z(eS=>{var Hp=Qa(),Vp=Object.prototype.hasOwnProperty,ii=typeof Map<"u";function Pn(){this._array=[],this._set=ii?new Map:Object.create(null)}Pn.fromArray=function(t,r){for(var n=new Pn,o=0,i=t.length;o<i;o++)n.add(t[o],r);return n};Pn.prototype.size=function(){return ii?this._set.size:Object.getOwnPropertyNames(this._set).length};Pn.prototype.add=function(t,r){var n=ii?t:Hp.toSetString(t),o=ii?this.has(t):Vp.call(this._set,n),i=this._array.length;(!o||r)&&this._array.push(t),o||(ii?this._set.set(t,i):this._set[n]=i)};Pn.prototype.has=function(t){if(ii)return this._set.has(t);var r=Hp.toSetString(t);return Vp.call(this._set,r)};Pn.prototype.indexOf=function(t){if(ii){var r=this._set.get(t);if(r>=0)return r}else{var n=Hp.toSetString(t);if(Vp.call(this._set,n))return this._set[n]}throw new Error('"'+t+'" is not in the set.')};Pn.prototype.at=function(t){if(t>=0&&t<this._array.length)return this._array[t];throw new Error("No element indexed by "+t)};Pn.prototype.toArray=function(){return this._array.slice()};eS.ArraySet=Pn});var nS=z(rS=>{var tS=Qa();function LO(e,t){var r=e.generatedLine,n=t.generatedLine,o=e.generatedColumn,i=t.generatedColumn;return n>r||n==r&&i>=o||tS.compareByGeneratedPositionsInflated(e,t)<=0}function Hu(){this._array=[],this._sorted=!0,this._last={generatedLine:-1,generatedColumn:0}}Hu.prototype.unsortedForEach=function(t,r){this._array.forEach(t,r)};Hu.prototype.add=function(t){LO(this._last,t)?(this._last=t,this._array.push(t)):(this._sorted=!1,this._array.push(t))};Hu.prototype.toArray=function(){return this._sorted||(this._array.sort(tS.compareByGeneratedPositionsInflated),this._sorted=!0),this._array};rS.MappingList=Hu});var Yp=z(oS=>{var mc=Gp(),qe=Qa(),Vu=jp().ArraySet,FO=nS().MappingList;function yr(e){e||(e={}),this._file=qe.getArg(e,"file",null),this._sourceRoot=qe.getArg(e,"sourceRoot",null),this._skipValidation=qe.getArg(e,"skipValidation",!1),this._ignoreInvalidMapping=qe.getArg(e,"ignoreInvalidMapping",!1),this._sources=new Vu,this._names=new Vu,this._mappings=new FO,this._sourcesContents=null}yr.prototype._version=3;yr.fromSourceMap=function(t,r){var n=t.sourceRoot,o=new yr(Object.assign(r||{},{file:t.file,sourceRoot:n}));return t.eachMapping(function(i){var a={generated:{line:i.generatedLine,column:i.generatedColumn}};i.source!=null&&(a.source=i.source,n!=null&&(a.source=qe.relative(n,a.source)),a.original={line:i.originalLine,column:i.originalColumn},i.name!=null&&(a.name=i.name)),o.addMapping(a)}),t.sources.forEach(function(i){var a=i;n!==null&&(a=qe.relative(n,i)),o._sources.has(a)||o._sources.add(a);var s=t.sourceContentFor(i);s!=null&&o.setSourceContent(i,s)}),o};yr.prototype.addMapping=function(t){var r=qe.getArg(t,"generated"),n=qe.getArg(t,"original",null),o=qe.getArg(t,"source",null),i=qe.getArg(t,"name",null);!this._skipValidation&&this._validateMapping(r,n,o,i)===!1||(o!=null&&(o=String(o),this._sources.has(o)||this._sources.add(o)),i!=null&&(i=String(i),this._names.has(i)||this._names.add(i)),this._mappings.add({generatedLine:r.line,generatedColumn:r.column,originalLine:n!=null&&n.line,originalColumn:n!=null&&n.column,source:o,name:i}))};yr.prototype.setSourceContent=function(t,r){var n=t;this._sourceRoot!=null&&(n=qe.relative(this._sourceRoot,n)),r!=null?(this._sourcesContents||(this._sourcesContents=Object.create(null)),this._sourcesContents[qe.toSetString(n)]=r):this._sourcesContents&&(delete this._sourcesContents[qe.toSetString(n)],Object.keys(this._sourcesContents).length===0&&(this._sourcesContents=null))};yr.prototype.applySourceMap=function(t,r,n){var o=r;if(r==null){if(t.file==null)throw new Error(`SourceMapGenerator.prototype.applySourceMap requires either an explicit source file, or the source map's "file" property. Both were omitted.`);o=t.file}var i=this._sourceRoot;i!=null&&(o=qe.relative(i,o));var a=new Vu,s=new Vu;this._mappings.unsortedForEach(function(c){if(c.source===o&&c.originalLine!=null){var l=t.originalPositionFor({line:c.originalLine,column:c.originalColumn});l.source!=null&&(c.source=l.source,n!=null&&(c.source=qe.join(n,c.source)),i!=null&&(c.source=qe.relative(i,c.source)),c.originalLine=l.line,c.originalColumn=l.column,l.name!=null&&(c.name=l.name))}var u=c.source;u!=null&&!a.has(u)&&a.add(u);var A=c.name;A!=null&&!s.has(A)&&s.add(A)},this),this._sources=a,this._names=s,t.sources.forEach(function(c){var l=t.sourceContentFor(c);l!=null&&(n!=null&&(c=qe.join(n,c)),i!=null&&(c=qe.relative(i,c)),this.setSourceContent(c,l))},this)};yr.prototype._validateMapping=function(t,r,n,o){if(r&&typeof r.line!="number"&&typeof r.column!="number"){var i="original.line and original.column are not numbers -- you probably meant to omit the original mapping entirely and only map the generated position. If so, pass null for the original mapping instead of an object with empty or null values.";if(this._ignoreInvalidMapping)return typeof console<"u"&&console.warn&&console.warn(i),!1;throw new Error(i)}if(!(t&&"line"in t&&"column"in t&&t.line>0&&t.column>=0&&!r&&!n&&!o)){if(t&&"line"in t&&"column"in t&&r&&"line"in r&&"column"in r&&t.line>0&&t.column>=0&&r.line>0&&r.column>=0&&n)return;var i="Invalid mapping: "+JSON.stringify({generated:t,source:n,original:r,name:o});if(this._ignoreInvalidMapping)return typeof console<"u"&&console.warn&&console.warn(i),!1;throw new Error(i)}};yr.prototype._serializeMappings=function(){for(var t=0,r=1,n=0,o=0,i=0,a=0,s="",c,l,u,A,m=this._mappings.toArray(),f=0,g=m.length;f<g;f++){if(l=m[f],c="",l.generatedLine!==r)for(t=0;l.generatedLine!==r;)c+=";",r++;else if(f>0){if(!qe.compareByGeneratedPositionsInflated(l,m[f-1]))continue;c+=","}c+=mc.encode(l.generatedColumn-t),t=l.generatedColumn,l.source!=null&&(A=this._sources.indexOf(l.source),c+=mc.encode(A-a),a=A,c+=mc.encode(l.originalLine-1-o),o=l.originalLine-1,c+=mc.encode(l.originalColumn-n),n=l.originalColumn,l.name!=null&&(u=this._names.indexOf(l.name),c+=mc.encode(u-i),i=u)),s+=c}return s};yr.prototype._generateSourcesContent=function(t,r){return t.map(function(n){if(!this._sourcesContents)return null;r!=null&&(n=qe.relative(r,n));var o=qe.toSetString(n);return Object.prototype.hasOwnProperty.call(this._sourcesContents,o)?this._sourcesContents[o]:null},this)};yr.prototype.toJSON=function(){var t={version:this._version,sources:this._sources.toArray(),names:this._names.toArray(),mappings:this._serializeMappings()};return this._file!=null&&(t.file=this._file),this._sourceRoot!=null&&(t.sourceRoot=this._sourceRoot),this._sourcesContents&&(t.sourcesContent=this._generateSourcesContent(t.sources,t.sourceRoot)),t};yr.prototype.toString=function(){return JSON.stringify(this.toJSON())};oS.SourceMapGenerator=yr});var iS=z(ai=>{ai.GREATEST_LOWER_BOUND=1;ai.LEAST_UPPER_BOUND=2;function $p(e,t,r,n,o,i){var a=Math.floor((t-e)/2)+e,s=o(r,n[a],!0);return s===0?a:s>0?t-a>1?$p(a,t,r,n,o,i):i==ai.LEAST_UPPER_BOUND?t<n.length?t:-1:a:a-e>1?$p(e,a,r,n,o,i):i==ai.LEAST_UPPER_BOUND?a:e<0?-1:e}ai.search=function(t,r,n,o){if(r.length===0)return-1;var i=$p(-1,r.length,t,r,n,o||ai.GREATEST_LOWER_BOUND);if(i<0)return-1;for(;i-1>=0&&n(r[i],r[i-1],!0)===0;)--i;return i}});var cS=z(sS=>{function PO(e){function t(o,i,a){var s=o[i];o[i]=o[a],o[a]=s}function r(o,i){return Math.round(o+Math.random()*(i-o))}function n(o,i,a,s){if(a<s){var c=r(a,s),l=a-1;t(o,c,s);for(var u=o[s],A=a;A<s;A++)i(o[A],u,!1)<=0&&(l+=1,t(o,l,A));t(o,l+1,A);var m=l+1;n(o,i,a,m-1),n(o,i,m+1,s)}}return n}function OO(e){let t=PO.toString();return new Function(`return ${t}`)()(e)}var aS=new WeakMap;sS.quickSort=function(e,t,r=0){let n=aS.get(t);n===void 0&&(n=OO(t),aS.set(t,n)),n(e,t,r,e.length-1)}});var fS=z(ju=>{var U=Qa(),Jp=iS(),Ma=jp().ArraySet,GO=Gp(),pc=cS().quickSort;function Te(e,t){var r=e;return typeof e=="string"&&(r=U.parseSourceMapInput(e)),r.sections!=null?new Fr(r,t):new dt(r,t)}Te.fromSourceMap=function(e,t){return dt.fromSourceMap(e,t)};Te.prototype._version=3;Te.prototype.__generatedMappings=null;Object.defineProperty(Te.prototype,"_generatedMappings",{configurable:!0,enumerable:!0,get:function(){return this.__generatedMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__generatedMappings}});Te.prototype.__originalMappings=null;Object.defineProperty(Te.prototype,"_originalMappings",{configurable:!0,enumerable:!0,get:function(){return this.__originalMappings||this._parseMappings(this._mappings,this.sourceRoot),this.__originalMappings}});Te.prototype._charIsMappingSeparator=function(t,r){var n=t.charAt(r);return n===";"||n===","};Te.prototype._parseMappings=function(t,r){throw new Error("Subclasses must implement _parseMappings")};Te.GENERATED_ORDER=1;Te.ORIGINAL_ORDER=2;Te.GREATEST_LOWER_BOUND=1;Te.LEAST_UPPER_BOUND=2;Te.prototype.eachMapping=function(t,r,n){var o=r||null,i=n||Te.GENERATED_ORDER,a;switch(i){case Te.GENERATED_ORDER:a=this._generatedMappings;break;case Te.ORIGINAL_ORDER:a=this._originalMappings;break;default:throw new Error("Unknown order of iteration.")}for(var s=this.sourceRoot,c=t.bind(o),l=this._names,u=this._sources,A=this._sourceMapURL,m=0,f=a.length;m<f;m++){var g=a[m],y=g.source===null?null:u.at(g.source);y!==null&&(y=U.computeSourceURL(s,y,A)),c({source:y,generatedLine:g.generatedLine,generatedColumn:g.generatedColumn,originalLine:g.originalLine,originalColumn:g.originalColumn,name:g.name===null?null:l.at(g.name)})}};Te.prototype.allGeneratedPositionsFor=function(t){var r=U.getArg(t,"line"),n={source:U.getArg(t,"source"),originalLine:r,originalColumn:U.getArg(t,"column",0)};if(n.source=this._findSourceIndex(n.source),n.source<0)return[];var o=[],i=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",U.compareByOriginalPositions,Jp.LEAST_UPPER_BOUND);if(i>=0){var a=this._originalMappings[i];if(t.column===void 0)for(var s=a.originalLine;a&&a.originalLine===s;)o.push({line:U.getArg(a,"generatedLine",null),column:U.getArg(a,"generatedColumn",null),lastColumn:U.getArg(a,"lastGeneratedColumn",null)}),a=this._originalMappings[++i];else for(var c=a.originalColumn;a&&a.originalLine===r&&a.originalColumn==c;)o.push({line:U.getArg(a,"generatedLine",null),column:U.getArg(a,"generatedColumn",null),lastColumn:U.getArg(a,"lastGeneratedColumn",null)}),a=this._originalMappings[++i]}return o};ju.SourceMapConsumer=Te;function dt(e,t){var r=e;typeof e=="string"&&(r=U.parseSourceMapInput(e));var n=U.getArg(r,"version"),o=U.getArg(r,"sources"),i=U.getArg(r,"names",[]),a=U.getArg(r,"sourceRoot",null),s=U.getArg(r,"sourcesContent",null),c=U.getArg(r,"mappings"),l=U.getArg(r,"file",null);if(n!=this._version)throw new Error("Unsupported version: "+n);a&&(a=U.normalize(a)),o=o.map(String).map(U.normalize).map(function(u){return a&&U.isAbsolute(a)&&U.isAbsolute(u)?U.relative(a,u):u}),this._names=Ma.fromArray(i.map(String),!0),this._sources=Ma.fromArray(o,!0),this._absoluteSources=this._sources.toArray().map(function(u){return U.computeSourceURL(a,u,t)}),this.sourceRoot=a,this.sourcesContent=s,this._mappings=c,this._sourceMapURL=t,this.file=l}dt.prototype=Object.create(Te.prototype);dt.prototype.consumer=Te;dt.prototype._findSourceIndex=function(e){var t=e;if(this.sourceRoot!=null&&(t=U.relative(this.sourceRoot,t)),this._sources.has(t))return this._sources.indexOf(t);var r;for(r=0;r<this._absoluteSources.length;++r)if(this._absoluteSources[r]==e)return r;return-1};dt.fromSourceMap=function(t,r){var n=Object.create(dt.prototype),o=n._names=Ma.fromArray(t._names.toArray(),!0),i=n._sources=Ma.fromArray(t._sources.toArray(),!0);n.sourceRoot=t._sourceRoot,n.sourcesContent=t._generateSourcesContent(n._sources.toArray(),n.sourceRoot),n.file=t._file,n._sourceMapURL=r,n._absoluteSources=n._sources.toArray().map(function(f){return U.computeSourceURL(n.sourceRoot,f,r)});for(var a=t._mappings.toArray().slice(),s=n.__generatedMappings=[],c=n.__originalMappings=[],l=0,u=a.length;l<u;l++){var A=a[l],m=new uS;m.generatedLine=A.generatedLine,m.generatedColumn=A.generatedColumn,A.source&&(m.source=i.indexOf(A.source),m.originalLine=A.originalLine,m.originalColumn=A.originalColumn,A.name&&(m.name=o.indexOf(A.name)),c.push(m)),s.push(m)}return pc(n.__originalMappings,U.compareByOriginalPositions),n};dt.prototype._version=3;Object.defineProperty(dt.prototype,"sources",{get:function(){return this._absoluteSources.slice()}});function uS(){this.generatedLine=0,this.generatedColumn=0,this.source=null,this.originalLine=null,this.originalColumn=null,this.name=null}var qp=U.compareByGeneratedPositionsDeflatedNoLine;function lS(e,t){let r=e.length,n=e.length-t;if(!(n<=1))if(n==2){let o=e[t],i=e[t+1];qp(o,i)>0&&(e[t]=i,e[t+1]=o)}else if(n<20)for(let o=t;o<r;o++)for(let i=o;i>t;i--){let a=e[i-1],s=e[i];if(qp(a,s)<=0)break;e[i-1]=s,e[i]=a}else pc(e,qp,t)}dt.prototype._parseMappings=function(t,r){var n=1,o=0,i=0,a=0,s=0,c=0,l=t.length,u=0,A={},m={},f=[],g=[],y,E,b,x,B;let I=0;for(;u<l;)if(t.charAt(u)===";")n++,u++,o=0,lS(g,I),I=g.length;else if(t.charAt(u)===",")u++;else{for(y=new uS,y.generatedLine=n,x=u;x<l&&!this._charIsMappingSeparator(t,x);x++);for(E=t.slice(u,x),b=[];u<x;)GO.decode(t,u,m),B=m.value,u=m.rest,b.push(B);if(b.length===2)throw new Error("Found a source, but no line and column");if(b.length===3)throw new Error("Found a source and line, but no column");if(y.generatedColumn=o+b[0],o=y.generatedColumn,b.length>1&&(y.source=s+b[1],s+=b[1],y.originalLine=i+b[2],i=y.originalLine,y.originalLine+=1,y.originalColumn=a+b[3],a=y.originalColumn,b.length>4&&(y.name=c+b[4],c+=b[4])),g.push(y),typeof y.originalLine=="number"){let S=y.source;for(;f.length<=S;)f.push(null);f[S]===null&&(f[S]=[]),f[S].push(y)}}lS(g,I),this.__generatedMappings=g;for(var w=0;w<f.length;w++)f[w]!=null&&pc(f[w],U.compareByOriginalPositionsNoSource);this.__originalMappings=[].concat(...f)};dt.prototype._findMapping=function(t,r,n,o,i,a){if(t[n]<=0)throw new TypeError("Line must be greater than or equal to 1, got "+t[n]);if(t[o]<0)throw new TypeError("Column must be greater than or equal to 0, got "+t[o]);return Jp.search(t,r,i,a)};dt.prototype.computeColumnSpans=function(){for(var t=0;t<this._generatedMappings.length;++t){var r=this._generatedMappings[t];if(t+1<this._generatedMappings.length){var n=this._generatedMappings[t+1];if(r.generatedLine===n.generatedLine){r.lastGeneratedColumn=n.generatedColumn-1;continue}}r.lastGeneratedColumn=1/0}};dt.prototype.originalPositionFor=function(t){var r={generatedLine:U.getArg(t,"line"),generatedColumn:U.getArg(t,"column")},n=this._findMapping(r,this._generatedMappings,"generatedLine","generatedColumn",U.compareByGeneratedPositionsDeflated,U.getArg(t,"bias",Te.GREATEST_LOWER_BOUND));if(n>=0){var o=this._generatedMappings[n];if(o.generatedLine===r.generatedLine){var i=U.getArg(o,"source",null);i!==null&&(i=this._sources.at(i),i=U.computeSourceURL(this.sourceRoot,i,this._sourceMapURL));var a=U.getArg(o,"name",null);return a!==null&&(a=this._names.at(a)),{source:i,line:U.getArg(o,"originalLine",null),column:U.getArg(o,"originalColumn",null),name:a}}}return{source:null,line:null,column:null,name:null}};dt.prototype.hasContentsOfAllSources=function(){return this.sourcesContent?this.sourcesContent.length>=this._sources.size()&&!this.sourcesContent.some(function(t){return t==null}):!1};dt.prototype.sourceContentFor=function(t,r){if(!this.sourcesContent)return null;var n=this._findSourceIndex(t);if(n>=0)return this.sourcesContent[n];var o=t;this.sourceRoot!=null&&(o=U.relative(this.sourceRoot,o));var i;if(this.sourceRoot!=null&&(i=U.urlParse(this.sourceRoot))){var a=o.replace(/^file:\/\//,"");if(i.scheme=="file"&&this._sources.has(a))return this.sourcesContent[this._sources.indexOf(a)];if((!i.path||i.path=="/")&&this._sources.has("/"+o))return this.sourcesContent[this._sources.indexOf("/"+o)]}if(r)return null;throw new Error('"'+o+'" is not in the SourceMap.')};dt.prototype.generatedPositionFor=function(t){var r=U.getArg(t,"source");if(r=this._findSourceIndex(r),r<0)return{line:null,column:null,lastColumn:null};var n={source:r,originalLine:U.getArg(t,"line"),originalColumn:U.getArg(t,"column")},o=this._findMapping(n,this._originalMappings,"originalLine","originalColumn",U.compareByOriginalPositions,U.getArg(t,"bias",Te.GREATEST_LOWER_BOUND));if(o>=0){var i=this._originalMappings[o];if(i.source===n.source)return{line:U.getArg(i,"generatedLine",null),column:U.getArg(i,"generatedColumn",null),lastColumn:U.getArg(i,"lastGeneratedColumn",null)}}return{line:null,column:null,lastColumn:null}};ju.BasicSourceMapConsumer=dt;function Fr(e,t){var r=e;typeof e=="string"&&(r=U.parseSourceMapInput(e));var n=U.getArg(r,"version"),o=U.getArg(r,"sections");if(n!=this._version)throw new Error("Unsupported version: "+n);this._sources=new Ma,this._names=new Ma;var i={line:-1,column:0};this._sections=o.map(function(a){if(a.url)throw new Error("Support for url field in sections not implemented.");var s=U.getArg(a,"offset"),c=U.getArg(s,"line"),l=U.getArg(s,"column");if(c<i.line||c===i.line&&l<i.column)throw new Error("Section offsets must be ordered and non-overlapping.");return i=s,{generatedOffset:{generatedLine:c+1,generatedColumn:l+1},consumer:new Te(U.getArg(a,"map"),t)}})}Fr.prototype=Object.create(Te.prototype);Fr.prototype.constructor=Te;Fr.prototype._version=3;Object.defineProperty(Fr.prototype,"sources",{get:function(){for(var e=[],t=0;t<this._sections.length;t++)for(var r=0;r<this._sections[t].consumer.sources.length;r++)e.push(this._sections[t].consumer.sources[r]);return e}});Fr.prototype.originalPositionFor=function(t){var r={generatedLine:U.getArg(t,"line"),generatedColumn:U.getArg(t,"column")},n=Jp.search(r,this._sections,function(i,a){var s=i.generatedLine-a.generatedOffset.generatedLine;return s||i.generatedColumn-a.generatedOffset.generatedColumn}),o=this._sections[n];return o?o.consumer.originalPositionFor({line:r.generatedLine-(o.generatedOffset.generatedLine-1),column:r.generatedColumn-(o.generatedOffset.generatedLine===r.generatedLine?o.generatedOffset.generatedColumn-1:0),bias:t.bias}):{source:null,line:null,column:null,name:null}};Fr.prototype.hasContentsOfAllSources=function(){return this._sections.every(function(t){return t.consumer.hasContentsOfAllSources()})};Fr.prototype.sourceContentFor=function(t,r){for(var n=0;n<this._sections.length;n++){var o=this._sections[n],i=o.consumer.sourceContentFor(t,!0);if(i||i==="")return i}if(r)return null;throw new Error('"'+t+'" is not in the SourceMap.')};Fr.prototype.generatedPositionFor=function(t){for(var r=0;r<this._sections.length;r++){var n=this._sections[r];if(n.consumer._findSourceIndex(U.getArg(t,"source"))!==-1){var o=n.consumer.generatedPositionFor(t);if(o){var i={line:o.line+(n.generatedOffset.generatedLine-1),column:o.column+(n.generatedOffset.generatedLine===o.line?n.generatedOffset.generatedColumn-1:0)};return i}}}return{line:null,column:null}};Fr.prototype._parseMappings=function(t,r){this.__generatedMappings=[],this.__originalMappings=[];for(var n=0;n<this._sections.length;n++)for(var o=this._sections[n],i=o.consumer._generatedMappings,a=0;a<i.length;a++){var s=i[a],c=o.consumer._sources.at(s.source);c!==null&&(c=U.computeSourceURL(o.consumer.sourceRoot,c,this._sourceMapURL)),this._sources.add(c),c=this._sources.indexOf(c);var l=null;s.name&&(l=o.consumer._names.at(s.name),this._names.add(l),l=this._names.indexOf(l));var u={source:c,generatedLine:s.generatedLine+(o.generatedOffset.generatedLine-1),generatedColumn:s.generatedColumn+(o.generatedOffset.generatedLine===s.generatedLine?o.generatedOffset.generatedColumn-1:0),originalLine:s.originalLine,originalColumn:s.originalColumn,name:l};this.__generatedMappings.push(u),typeof u.originalLine=="number"&&this.__originalMappings.push(u)}pc(this.__generatedMappings,U.compareByGeneratedPositionsDeflated),pc(this.__originalMappings,U.compareByOriginalPositions)};ju.IndexedSourceMapConsumer=Fr});var dS=z(AS=>{var UO=Yp().SourceMapGenerator,Yu=Qa(),HO=/(\r?\n)/,VO=10,_a="$$$isSourceNode$$$";function Zt(e,t,r,n,o){this.children=[],this.sourceContents={},this.line=e??null,this.column=t??null,this.source=r??null,this.name=o??null,this[_a]=!0,n!=null&&this.add(n)}Zt.fromStringWithSourceMap=function(t,r,n){var o=new Zt,i=t.split(HO),a=0,s=function(){var m=g(),f=g()||"";return m+f;function g(){return a<i.length?i[a++]:void 0}},c=1,l=0,u=null;return r.eachMapping(function(m){if(u!==null)if(c<m.generatedLine)A(u,s()),c++,l=0;else{var f=i[a]||"",g=f.substr(0,m.generatedColumn-l);i[a]=f.substr(m.generatedColumn-l),l=m.generatedColumn,A(u,g),u=m;return}for(;c<m.generatedLine;)o.add(s()),c++;if(l<m.generatedColumn){var f=i[a]||"";o.add(f.substr(0,m.generatedColumn)),i[a]=f.substr(m.generatedColumn),l=m.generatedColumn}u=m},this),a<i.length&&(u&&A(u,s()),o.add(i.splice(a).join(""))),r.sources.forEach(function(m){var f=r.sourceContentFor(m);f!=null&&(n!=null&&(m=Yu.join(n,m)),o.setSourceContent(m,f))}),o;function A(m,f){if(m===null||m.source===void 0)o.add(f);else{var g=n?Yu.join(n,m.source):m.source;o.add(new Zt(m.originalLine,m.originalColumn,g,f,m.name))}}};Zt.prototype.add=function(t){if(Array.isArray(t))t.forEach(function(r){this.add(r)},this);else if(t[_a]||typeof t=="string")t&&this.children.push(t);else throw new TypeError("Expected a SourceNode, string, or an array of SourceNodes and strings. Got "+t);return this};Zt.prototype.prepend=function(t){if(Array.isArray(t))for(var r=t.length-1;r>=0;r--)this.prepend(t[r]);else if(t[_a]||typeof t=="string")this.children.unshift(t);else throw new TypeError("Expected a SourceNode, string, or an array of SourceNodes and strings. Got "+t);return this};Zt.prototype.walk=function(t){for(var r,n=0,o=this.children.length;n<o;n++)r=this.children[n],r[_a]?r.walk(t):r!==""&&t(r,{source:this.source,line:this.line,column:this.column,name:this.name})};Zt.prototype.join=function(t){var r,n,o=this.children.length;if(o>0){for(r=[],n=0;n<o-1;n++)r.push(this.children[n]),r.push(t);r.push(this.children[n]),this.children=r}return this};Zt.prototype.replaceRight=function(t,r){var n=this.children[this.children.length-1];return n[_a]?n.replaceRight(t,r):typeof n=="string"?this.children[this.children.length-1]=n.replace(t,r):this.children.push("".replace(t,r)),this};Zt.prototype.setSourceContent=function(t,r){this.sourceContents[Yu.toSetString(t)]=r};Zt.prototype.walkSourceContents=function(t){for(var r=0,n=this.children.length;r<n;r++)this.children[r][_a]&&this.children[r].walkSourceContents(t);for(var o=Object.keys(this.sourceContents),r=0,n=o.length;r<n;r++)t(Yu.fromSetString(o[r]),this.sourceContents[o[r]])};Zt.prototype.toString=function(){var t="";return this.walk(function(r){t+=r}),t};Zt.prototype.toStringWithSourceMap=function(t){var r={code:"",line:1,column:0},n=new UO(t),o=!1,i=null,a=null,s=null,c=null;return this.walk(function(l,u){r.code+=l,u.source!==null&&u.line!==null&&u.column!==null?((i!==u.source||a!==u.line||s!==u.column||c!==u.name)&&n.addMapping({source:u.source,original:{line:u.line,column:u.column},generated:{line:r.line,column:r.column},name:u.name}),i=u.source,a=u.line,s=u.column,c=u.name,o=!0):o&&(n.addMapping({generated:{line:r.line,column:r.column}}),i=null,o=!1);for(var A=0,m=l.length;A<m;A++)l.charCodeAt(A)===VO?(r.line++,r.column=0,A+1===m?(i=null,o=!1):o&&n.addMapping({source:u.source,original:{line:u.line,column:u.column},generated:{line:r.line,column:r.column},name:u.name})):r.column++}),this.walkSourceContents(function(l,u){n.setSourceContent(l,u)}),{code:r.code,map:n}};AS.SourceNode=Zt});var mS=z($u=>{$u.SourceMapGenerator=Yp().SourceMapGenerator;$u.SourceMapConsumer=fS().SourceMapConsumer;$u.SourceNode=dS().SourceNode});var pS,gS,hS=d(()=>{"use client";Xt();pS=p(O(),1),gS=(0,ve.createSvgIcon)((0,pS.jsx)("path",{d:"M19 19H5V5h7V3H5c-1.11 0-2 .9-2 2v14c0 1.1.89 2 2 2h14c1.1 0 2-.9 2-2v-7h-2zM14 3v2h3.59l-9.83 9.83 1.41 1.41L19 6.41V10h2V3z"}),"OpenInNew")});function Ju(e){let{children:t,...r}=e;return(0,qu.jsxs)(CS.Link,{...r,target:"_blank",rel:"noopener noreferrer",children:[t," ",(0,qu.jsx)(gS,{fontSize:"small"})]})}var qu,CS,yS=d(()=>{qu=p(O(),1);hS();CS=p(V(),1)});function Wp({text:e,extra:t}){let{classes:r}=jO(),n=t?`supporting data: ${JSON.stringify(t,null,2)}`:"",o=[e,n].filter(Boolean).join(`
 `),i=encodeURIComponent(`I got this error from JBrowse, here is the stack trace:
 
 \`\`\`
 ${e}
 \`\`\`
 ${n}
-`),a=`https://github.com/GMOD/jbrowse-components/issues/new?labels=bug&title=JBrowse+issue&body=${i}`,s=`mailto:${AE}?subject=JBrowse%202%20error&body=${i}`;return(0,nn.jsxs)(nn.Fragment,{children:[(0,nn.jsxs)(vc.Typography,{children:["Post a new issue at"," ",(0,nn.jsx)(Qc,{href:a,children:"GitHub"})," or send an email to ",(0,nn.jsx)(Qc,{href:s,children:AE})]}),(0,nn.jsx)("pre",{className:r.pre,children:o})]})}var nn,vc,AE,Ek,uE=p(()=>{nn=f(R(),1),vc=f(O(),1);lE();Re();AE="jbrowse2@berkeley.edu",Ek=Y()(e=>({pre:{background:(0,vc.alpha)(e.palette.error.main,.2),border:`1px solid ${e.palette.divider}`,overflow:"auto",margin:20,maxHeight:300}}))});function Cf({message:e,children:t,variant:r="body2",...n}){let{classes:o}=Ik();return(0,fE.jsx)(dE.Typography,{className:Cc(o.dots,n.className),...n,variant:r,children:e||"Loading"})}var fE,dE,Ik,mE=p(()=>{fE=f(R(),1),dE=f(O(),1);Re();Ik=Y()({dots:{"&::after":{display:"inline-block",content:'""',width:"1em",textAlign:"left",animation:`${zu`
+`),a=`https://github.com/GMOD/jbrowse-components/issues/new?labels=bug&title=JBrowse+issue&body=${i}`,s=`mailto:${xS}?subject=JBrowse%202%20error&body=${i}`;return(0,On.jsxs)(On.Fragment,{children:[(0,On.jsxs)(Wu.Typography,{children:["Post a new issue at"," ",(0,On.jsx)(Ju,{href:a,children:"GitHub"})," or send an email to ",(0,On.jsx)(Ju,{href:s,children:xS})]}),(0,On.jsx)("pre",{className:r.pre,children:o})]})}var On,Wu,xS,jO,ES=d(()=>{On=p(O(),1),Wu=p(V(),1);yS();$e();xS="jbrowse2@berkeley.edu",jO=X()(e=>({pre:{background:(0,Wu.alpha)(e.palette.error.main,.2),border:`1px solid ${e.palette.divider}`,overflow:"auto",margin:20,maxHeight:300}}))});function zp({message:e,children:t,variant:r="body2",...n}){let{classes:o}=YO();return(0,bS.jsx)(IS.Typography,{className:Ou(o.dots,n.className),...n,variant:r,children:e||"Loading"})}var bS,IS,YO,wS=d(()=>{bS=p(O(),1),IS=p(V(),1);$e();YO=X()({dots:{"&::after":{display:"inline-block",content:'""',width:"1em",textAlign:"left",animation:`${nu`
       0% {
         content: '';
       }
@@ -18,26 +27,26 @@ ${n}
       75% {
         content: '...';
       }
-      `} 1.2s infinite ease-in-out`}}})});var gE=V((kO,pE)=>{pE.exports=function(){var e=document.getSelection();if(!e.rangeCount)return function(){};for(var t=document.activeElement,r=[],n=0;n<e.rangeCount;n++)r.push(e.getRangeAt(n));switch(t.tagName.toUpperCase()){case"INPUT":case"TEXTAREA":t.blur();break;default:t=null;break}return e.removeAllRanges(),function(){e.type==="Caret"&&e.removeAllRanges(),e.rangeCount||r.forEach(function(o){e.addRange(o)}),t&&t.focus()}}});var EE=V((DO,CE)=>{"use strict";var xk=gE(),hE={"text/plain":"Text","text/html":"Url",default:"Text"},yk="Copy to clipboard: #{key}, Enter";function wk(e){var t=(/mac os x/i.test(navigator.userAgent)?"\u2318":"Ctrl")+"+C";return e.replace(/#{\s*key\s*}/g,t)}function bk(e,t){var r,n,o,i,a,s,c=!1;t||(t={}),r=t.debug||!1;try{o=xk(),i=document.createRange(),a=document.getSelection(),s=document.createElement("span"),s.textContent=e,s.ariaHidden="true",s.style.all="unset",s.style.position="fixed",s.style.top=0,s.style.clip="rect(0, 0, 0, 0)",s.style.whiteSpace="pre",s.style.webkitUserSelect="text",s.style.MozUserSelect="text",s.style.msUserSelect="text",s.style.userSelect="text",s.addEventListener("copy",function(A){if(A.stopPropagation(),t.format)if(A.preventDefault(),typeof A.clipboardData>"u"){r&&console.warn("unable to use e.clipboardData"),r&&console.warn("trying IE specific stuff"),window.clipboardData.clearData();var u=hE[t.format]||hE.default;window.clipboardData.setData(u,e)}else A.clipboardData.clearData(),A.clipboardData.setData(t.format,e);t.onCopy&&(A.preventDefault(),t.onCopy(A.clipboardData))}),document.body.appendChild(s),i.selectNodeContents(s),a.addRange(i);var l=document.execCommand("copy");if(!l)throw new Error("copy command was unsuccessful");c=!0}catch(A){r&&console.error("unable to copy using execCommand: ",A),r&&console.warn("trying IE specific stuff");try{window.clipboardData.setData(t.format||"text",e),t.onCopy&&t.onCopy(window.clipboardData),c=!0}catch(u){r&&console.error("unable to copy using clipboardData: ",u),r&&console.error("falling back to prompt"),n=wk("message"in t?t.message:yk),window.prompt(n,e)}}finally{a&&(typeof a.removeRange=="function"?a.removeRange(i):a.removeAllRanges()),s&&document.body.removeChild(s),o()}return c}CE.exports=bk});var bE={};dt(bE,{default:()=>wE});async function yE(e){let t=await fetch(e);if(!t.ok)throw new Error(`HTTP ${t.status} fetching ${e}: ${await t.text()}`);return t.text()}async function Bk(e){return JSON.parse(await yE(e))}async function vk(e){if(Ef[e])return Ef[e];let t=new URL(e).search,r=await yE(e),n=Sk.exec(r)?.[1]??"",o=await Bk(new URL(n,e).href+t),i=new xE.SourceMapConsumer(o);return Ef[e]=i,i}async function Mk(e){let t=[];for(let r of e.split(`
-`)){let n=Qk.exec(r);if(!n){t.push(r);continue}let o=n[2],a=(await vk(o)).originalPositionFor({line:+n[3],column:+n[4]});if(!a.source||!a.line||!a.column){t.push(r);continue}t.push(`${a.source}:${a.line}:${a.column+1} (${n[1].trim()})`)}return t.join(`
-`)}function _k(e,t){return e.startsWith("Error:")?e.slice(`${t}`.length):e}function Tk(e){return typeof e=="object"&&e!==null&&"stack"in e?`${e.stack}`:""}function wE({error:e,onClose:t,extra:r}){let[n,o]=(0,Ci.useState)(),[i,a]=(0,Ci.useState)(),[s,c]=(0,Ci.useState)(!1),l=e?`${e}`:"",A=_k(Tk(e),l);(0,Ci.useEffect)(()=>{(async()=>{try{o(await Mk(A))}catch(d){console.error(d),o(A),a(d)}})()},[A]);let u=window.JBrowseSession?.version,m=[i?"Error loading source map, showing raw stack trace below:":"",l.length>IE?`${l.slice(0,IE)}...`:l,n||"No stack trace available",u?`JBrowse ${u}`:""].filter(Boolean).join(`
-`);return(0,rr.jsxs)(Ht.Dialog,{open:!0,onClose:t,maxWidth:"xl",children:[(0,rr.jsxs)(Ht.DialogTitle,{children:["Stack trace",(0,rr.jsx)(Ht.IconButton,{onClick:t,sx:{position:"absolute",right:8,top:8},children:(0,rr.jsx)(Ic,{})})]}),(0,rr.jsx)(Ht.DialogContent,{children:n===void 0?(0,rr.jsx)(Cf,{variant:"h6"}):(0,rr.jsx)(hf,{text:m,extra:r})}),(0,rr.jsxs)(Ht.DialogActions,{children:[(0,rr.jsx)(Ht.Button,{variant:"contained",color:"secondary",onClick:async()=>{let{default:d}=await Promise.resolve().then(()=>f(EE(),1));d(m),c(!0),setTimeout(()=>{c(!1)},1e3)},children:s?"Copied!":"Copy stack trace to clipboard"}),(0,rr.jsx)(Ht.Button,{variant:"contained",color:"primary",onClick:t,children:"Close"})]})]})}var rr,Ci,Ht,xE,Ef,Sk,Qk,IE,BE=p(()=>{rr=f(R(),1),Ci=f(M(),1);rf();Ht=f(O(),1),xE=f(oE(),1);uE();mE();Ef={},Sk=/\/\/# sourceMappingURL=(.*)/,Qk=/(.*)((?:https?|file):\/\/.*):(\d+):(\d+)/;IE=1e4});function Dk(e){let t="",r="is not assignable",n=e.indexOf(r);if(n!==-1){let o=e.slice(0,n+r.length),i=/.*at path "(.*)" snapshot `(.*)` is not assignable/m.exec(o);i&&(e=`Failed to load element at ${i[1]}...Failed element had snapshot`,t=i[2]);let a=/.*snapshot `(.*)` is not assignable/.exec(o);a&&(e="Failed to load element...Failed element had snapshot",t=a[1])}return t}function Nk({error:e,onReset:t}){let{classes:r}=SE(),[n,o]=(0,Ii.useState)(!1);return(0,Dt.jsxs)("div",{className:r.iconFloat,children:[typeof e=="object"&&e&&"stack"in e?(0,Dt.jsx)(Ei.Tooltip,{title:"Get stack trace",children:(0,Dt.jsx)(Ei.IconButton,{onClick:()=>{o(!0)},color:"primary",children:(0,Dt.jsx)(MC,{})})}):null,t?(0,Dt.jsx)(Ei.Tooltip,{title:"Retry",children:(0,Dt.jsx)(Ei.IconButton,{onClick:t,color:"primary",children:(0,Dt.jsx)(SC,{})})}):null,n?(0,Dt.jsx)(Ii.Suspense,{fallback:null,children:(0,Dt.jsx)(kk,{error:e,onClose:()=>{o(!1)}})}):null]})}function Lk({error:e,onReset:t}){let{classes:r}=SE(),n=`${e}`,o=n.indexOf("expected an instance of"),i=o!==-1?n.slice(0,o):n,a=Dk(n);return(0,Dt.jsxs)(nf,{children:[i.slice(0,1e4),(0,Dt.jsx)(Nk,{error:e,onReset:t}),a?(0,Dt.jsx)("pre",{className:r.bg,children:JSON.stringify(JSON.parse(a),null,2)}):null]})}var Dt,Ii,Ei,kk,SE,QE,vE=p(()=>{Dt=f(R(),1),Ii=f(M(),1);QC();_C();Ei=f(O(),1);kC();Re();kk=(0,Ii.lazy)(()=>Promise.resolve().then(()=>(BE(),bE))),SE=Y()(e=>({bg:{background:e.palette.divider,border:"1px solid black",margin:20},iconFloat:{float:"right",marginLeft:100}}));QE=Lk});var _E=V((HO,ME)=>{"use strict";var Rk=/["'&<>]/;ME.exports=Fk;function Fk(e){var t=""+e,r=Rk.exec(t);if(!r)return t;var n,o="",i=0,a=0;for(i=r.index;i<t.length;i++){switch(t.charCodeAt(i)){case 34:n="&quot;";break;case 38:n="&amp;";break;case 39:n="&#39;";break;case 60:n="&lt;";break;case 62:n="&gt;";break;default:continue}a!==i&&(o+=t.substring(a,i)),a=i+1,o+=n}return a!==i?o+t.substring(a,i):o}});function Mc(e,t=0){let r=e.getUint32(t,!0);return e.getUint32(t+4,!0)*4294967296+r}var TE=p(()=>{});function Pk(e,t){let r=new Array(t+1);r[0]=[0,0];let n=new DataView(e.buffer,e.byteOffset,e.byteLength);for(let o=0;o<t;o+=1){let i=o*If;r[o+1]=[Mc(n,i),Mc(n,i+8)]}return r}function Ok(e,t){let r=0,n=e.length;for(;r<n;){let o=r+n>>>1;e[o][1]<=t?r=o+1:n=o}return r}var If,Da,kE=p(()=>{TE();If=16;Da=class{filehandle;index;constructor({filehandle:t}){this.filehandle=t}_getIndex(){return this.index||(this.index=this._readIndex().catch(t=>{throw this.index=void 0,t})),this.index}async _readIndex(){let t=await this.filehandle.read(8,0),r=Mc(new DataView(t.buffer,t.byteOffset,t.byteLength));if(r===0)return[[0,0]];if(r>Number.MAX_SAFE_INTEGER/If)throw new TypeError("integer overflow");let n=await this.filehandle.read(If*r,8);return Pk(n,r)}async getRelevantBlocksForRead(t,r){if(t===0)return{blocks:[],nextCompressedPosition:void 0};let n=await this._getIndex(),o=r+t,i=Ok(n,r)-1,a=i+1;for(;a<n.length&&n[a][1]<o;)a+=1;return{blocks:n.slice(i,a),nextCompressedPosition:n[a]?.[0]}}}});var xf,yf,Na,bn,La,DE,NE,wf=p(()=>{xf=0,yf=2,Na=4,bn=0,La=1,DE=2,NE=-5});function Gk(e,t){return Object.prototype.hasOwnProperty.call(e,t)}function LE(e){for(var t=Array.prototype.slice.call(arguments,1);t.length;){var r=t.shift();if(r){if(typeof r!="object")throw new TypeError(r+"must be non-object");for(var n in r)Gk(r,n)&&(e[n]=r[n])}}return e}function Tc(e,t){return e.length===t?e:e.subarray?e.subarray(0,t):(e.length=t,e)}var Ra,Fa,xi,Nr,_c,on,Bn,uo,Pa=p(()=>{Ra={arraySet:function(e,t,r,n,o){if(t.subarray&&e.subarray){e.set(t.subarray(r,r+n),o);return}for(var i=0;i<n;i++)e[o+i]=t[r+i]},flattenChunks:function(e){var t,r,n,o,i,a;for(n=0,t=0,r=e.length;t<r;t++)n+=e[t].length;for(a=new Uint8Array(n),o=0,t=0,r=e.length;t<r;t++)i=e[t],a.set(i,o),o+=i.length;return a},Buf8:function(e){return new Uint8Array(e)},Buf16:function(e){return new Uint16Array(e)},Buf32:function(e){return new Int32Array(e)}},Fa={arraySet:function(e,t,r,n,o){for(var i=0;i<n;i++)e[o+i]=t[r+i]},flattenChunks:function(e){return[].concat.apply([],e)},Buf8:function(e){return new Array(e)},Buf16:function(e){return new Array(e)},Buf32:function(e){return new Array(e)}},xi=()=>{let e=typeof Uint8Array<"u"&&typeof Uint16Array<"u"&&typeof Int32Array<"u";return xi=()=>e,e},Nr=(e,t,r,n,o)=>(Nr=xi()?Ra.arraySet:Fa.arraySet,Nr(e,t,r,n,o)),_c=e=>(_c=xi()?Ra.flattenChunks:Fa.flattenChunks,_c(e)),on=e=>(on=xi()?Ra.Buf8:Fa.Buf8,on(e)),Bn=e=>(Bn=xi()?Ra.Buf16:Fa.Buf16,Bn(e)),uo=e=>(uo=xi()?Ra.Buf32:Fa.Buf32,uo(e))});function Bf(e){var t,r,n,o,i,a=e.length,s=0;for(o=0;o<a;o++)r=e.charCodeAt(o),(r&64512)===55296&&o+1<a&&(n=e.charCodeAt(o+1),(n&64512)===56320&&(r=65536+(r-55296<<10)+(n-56320),o++)),s+=r<128?1:r<2048?2:r<65536?3:4;for(t=new Uint8Array(s),i=0,o=0;i<s;o++)r=e.charCodeAt(o),(r&64512)===55296&&o+1<a&&(n=e.charCodeAt(o+1),(n&64512)===56320&&(r=65536+(r-55296<<10)+(n-56320),o++)),r<128?t[i++]=r:r<2048?(t[i++]=192|r>>>6,t[i++]=128|r&63):r<65536?(t[i++]=224|r>>>12,t[i++]=128|r>>>6&63,t[i++]=128|r&63):(t[i++]=240|r>>>18,t[i++]=128|r>>>12&63,t[i++]=128|r>>>6&63,t[i++]=128|r&63);return t}function Uk(e,t){if(t<65534&&(e.subarray&&FE()||!e.subarray&&RE()))return String.fromCharCode.apply(null,Tc(e,t));for(var r="",n=0;n<t;n++)r+=String.fromCharCode(e[n]);return r}function PE(e){for(var t=new Uint8Array(e.length),r=0,n=t.length;r<n;r++)t[r]=e.charCodeAt(r);return t}function OE(e,t){var r,n,o,i,a=t||e.length,s=new Array(a*2);for(n=0,r=0;r<a;){if(o=e[r++],o<128){s[n++]=o;continue}if(i=bf(o),i>4){s[n++]=65533,r+=i-1;continue}for(o&=i===2?31:i===3?15:7;i>1&&r<a;)o=o<<6|e[r++]&63,i--;if(i>1){s[n++]=65533;continue}o<65536?s[n++]=o:(o-=65536,s[n++]=55296|o>>10&1023,s[n++]=56320|o&1023)}return Uk(s,n)}function GE(e,t){var r;for(t=t||e.length,t>e.length&&(t=e.length),r=t-1;r>=0&&(e[r]&192)===128;)r--;return r<0||r===0?t:r+bf(e[r])>t?r:t}var RE,FE,bf,UE=p(()=>{Pa();RE=function(){let e=!0;try{String.fromCharCode.apply(null,[0])}catch{e=!1}return RE=()=>e,e},FE=function(){let e=!0;try{String.fromCharCode.apply(null,new Uint8Array(1))}catch{e=!1}return FE=()=>e,e},bf=function(e){for(var t=on(256),r=0;r<256;r++)t[r]=r>=252?6:r>=248?5:r>=240?4:r>=224?3:r>=192?2:1;return t[254]=t[254]=1,bf=n=>t[n],t[e]}});function Sf(){this.text=0,this.time=0,this.xflags=0,this.os=0,this.extra=null,this.extra_len=0,this.name="",this.comment="",this.hcrc=0,this.done=!1}var HE=p(()=>{});function Oa(e,t,r,n){for(var o=e&65535|0,i=e>>>16&65535|0,a=0;r!==0;){a=r>2e3?2e3:r,r-=a;do o=o+t[n++]|0,i=i+o|0;while(--a);o%=65521,i%=65521}return o|i<<16|0}var jE=p(()=>{});function Hk(){for(var e,t=[],r=0;r<256;r++){e=r;for(var n=0;n<8;n++)e=e&1?3988292384^e>>>1:e>>>1;t[r]=e}return t}function nr(e,t,r,n){var o=qE(),i=n+r;e^=-1;for(var a=n;a<i;a++)e=e>>>8^o[(e^t[a])&255];return e^-1}var qE,JE=p(()=>{qE=function(){let e=Hk();return qE=()=>e,e}});function Qf(e,t){var r,n,o,i,a,s,c,l,A,u,m,d,g,C,y,I,E,b,x,w,Q,S,k,N,_;r=e.state,n=e.next_in,N=e.input,o=n+(e.avail_in-5),i=e.next_out,_=e.output,a=i-(t-e.avail_out),s=i+(e.avail_out-257),c=r.dmax,l=r.wsize,A=r.whave,u=r.wnext,m=r.window,d=r.hold,g=r.bits,C=r.lencode,y=r.distcode,I=(1<<r.lenbits)-1,E=(1<<r.distbits)-1;e:do{g<15&&(d+=N[n++]<<g,g+=8,d+=N[n++]<<g,g+=8),b=C[d&I];t:for(;;){if(x=b>>>24,d>>>=x,g-=x,x=b>>>16&255,x===0)_[i++]=b&65535;else if(x&16){w=b&65535,x&=15,x&&(g<x&&(d+=N[n++]<<g,g+=8),w+=d&(1<<x)-1,d>>>=x,g-=x),g<15&&(d+=N[n++]<<g,g+=8,d+=N[n++]<<g,g+=8),b=y[d&E];r:for(;;){if(x=b>>>24,d>>>=x,g-=x,x=b>>>16&255,x&16){if(Q=b&65535,x&=15,g<x&&(d+=N[n++]<<g,g+=8,g<x&&(d+=N[n++]<<g,g+=8)),Q+=d&(1<<x)-1,Q>c){e.msg="invalid distance too far back",r.mode=kc;break e}if(d>>>=x,g-=x,x=i-a,Q>x){if(x=Q-x,x>A&&r.sane){e.msg="invalid distance too far back",r.mode=kc;break e}if(S=0,k=m,u===0){if(S+=l-x,x<w){w-=x;do _[i++]=m[S++];while(--x);S=i-Q,k=_}}else if(u<x){if(S+=l+u-x,x-=u,x<w){w-=x;do _[i++]=m[S++];while(--x);if(S=0,u<w){x=u,w-=x;do _[i++]=m[S++];while(--x);S=i-Q,k=_}}}else if(S+=u-x,x<w){w-=x;do _[i++]=m[S++];while(--x);S=i-Q,k=_}for(;w>2;)_[i++]=k[S++],_[i++]=k[S++],_[i++]=k[S++],w-=3;w&&(_[i++]=k[S++],w>1&&(_[i++]=k[S++]))}else{S=i-Q;do _[i++]=_[S++],_[i++]=_[S++],_[i++]=_[S++],w-=3;while(w>2);w&&(_[i++]=_[S++],w>1&&(_[i++]=_[S++]))}}else if((x&64)===0){b=y[(b&65535)+(d&(1<<x)-1)];continue r}else{e.msg="invalid distance code",r.mode=kc;break e}break}}else if((x&64)===0){b=C[(b&65535)+(d&(1<<x)-1)];continue t}else if(x&32){r.mode=jk;break e}else{e.msg="invalid literal/length code",r.mode=kc;break e}break}}while(n<o&&i<s);w=g>>3,n-=w,g-=w<<3,d&=(1<<g)-1,e.next_in=n,e.next_out=i,e.avail_in=n<o?5+(o-n):5-(n-o),e.avail_out=i<s?257+(s-i):257-(i-s),r.hold=d,r.bits=g}var kc,jk,VE=p(()=>{kc=30,jk=12});function fo(e,t,r,n,o,i,a,s){var c=s.bits,l=0,A=0,u=0,m=0,d=0,g=0,C=0,y=0,I=0,E=0,b,x,w,Q,S,k=null,N=0,_,v=Bn(yi+1),L=Bn(yi+1),U=null,W=0,se,Te,Oe;for(l=0;l<=yi;l++)v[l]=0;for(A=0;A<n;A++)v[t[r+A]]++;for(d=c,m=yi;m>=1&&v[m]===0;m--);if(d>m&&(d=m),m===0)return o[i++]=1<<24|64<<16|0,o[i++]=1<<24|64<<16|0,s.bits=1,0;for(u=1;u<m&&v[u]===0;u++);for(d<u&&(d=u),y=1,l=1;l<=yi;l++)if(y<<=1,y-=v[l],y<0)return-1;if(y>0&&(e===WE||m!==1))return-1;for(L[1]=0,l=1;l<yi;l++)L[l+1]=L[l]+v[l];for(A=0;A<n;A++)t[r+A]!==0&&(a[L[t[r+A]]++]=A);if(e===WE?(k=U=a,_=19):e===vf?(k=qk,N-=257,U=Jk,W-=257,_=256):(k=Vk,U=Yk,_=-1),E=0,A=0,l=u,S=i,g=d,C=0,w=-1,I=1<<d,Q=I-1,e===vf&&I>YE||e===$E&&I>zE)return 1;for(;;){se=l-C,a[A]<_?(Te=0,Oe=a[A]):a[A]>_?(Te=U[W+a[A]],Oe=k[N+a[A]]):(Te=96,Oe=0),b=1<<l-C,x=1<<g,u=x;do x-=b,o[S+(E>>C)+x]=se<<24|Te<<16|Oe|0;while(x!==0);for(b=1<<l-1;E&b;)b>>=1;if(b!==0?(E&=b-1,E+=b):E=0,A++,--v[l]===0){if(l===m)break;l=t[r+a[A]]}if(l>d&&(E&Q)!==w){for(C===0&&(C=d),S+=u,g=l-C,y=1<<g;g+C<m&&(y-=v[g+C],!(y<=0));)g++,y<<=1;if(I+=1<<g,e===vf&&I>YE||e===$E&&I>zE)return 1;w=E&Q,o[w]=d<<24|g<<16|S-i|0}}return E!==0&&(o[S+E]=l-C<<24|64<<16|0),s.bits=d,0}var yi,YE,zE,WE,vf,$E,qk,Jk,Vk,Yk,KE=p(()=>{Pa();yi=15,YE=852,zE=592,WE=0,vf=1,$E=2,qk=[3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0],Jk=[16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78],Vk=[1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0],Yk=[16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64]});function xI(e){return(e>>>24&255)+(e>>>8&65280)+((e&65280)<<8)+((e&255)<<24)}function rD(){this.mode=0,this.last=!1,this.wrap=0,this.havedict=!1,this.flags=0,this.dmax=0,this.check=0,this.total=0,this.head=null,this.wbits=0,this.wsize=0,this.whave=0,this.wnext=0,this.window=null,this.hold=0,this.bits=0,this.length=0,this.offset=0,this.extra=0,this.lencode=null,this.distcode=null,this.lenbits=0,this.distbits=0,this.ncode=0,this.nlen=0,this.ndist=0,this.have=0,this.next=null,this.lens=Bn(320),this.work=Bn(288),this.lendyn=null,this.distdyn=null,this.sane=0,this.back=0,this.was=0}function nD(e){var t;return!e||!e.state?or:(t=e.state,e.total_in=e.total_out=t.total=0,e.msg="",t.wrap&&(e.adler=t.wrap&1),t.mode=SI,t.last=0,t.havedict=0,t.dmax=32768,t.head=null,t.hold=0,t.bits=0,t.lencode=t.lendyn=uo(eD),t.distcode=t.distdyn=uo(tD),t.sane=1,t.back=-1,mo)}function oD(e){var t;return!e||!e.state?or:(t=e.state,t.wsize=0,t.whave=0,t.wnext=0,nD(e))}function iD(e,t){var r,n;return!e||!e.state||(n=e.state,t<0?(r=0,t=-t):(r=(t>>4)+1,t<48&&(t&=15)),t&&(t<8||t>15))?or:(n.window!==null&&n.wbits!==t&&(n.window=null),n.wrap=r,n.wbits=t,oD(e))}function QI(e,t){var r,n;return e?(n=new rD,e.state=n,n.window=null,r=iD(e,t),r!==mo&&(e.state=null),r):or}function aD(e){if(yI){var t;for(kf=uo(512),Df=uo(32),t=0;t<144;)e.lens[t++]=8;for(;t<256;)e.lens[t++]=9;for(;t<280;)e.lens[t++]=7;for(;t<288;)e.lens[t++]=8;for(fo(wI,e.lens,0,288,kf,0,e.work,{bits:9}),t=0;t<32;)e.lens[t++]=5;fo(bI,e.lens,0,32,Df,0,e.work,{bits:5}),yI=!1}e.lencode=kf,e.lenbits=9,e.distcode=Df,e.distbits=5}function vI(e,t,r,n){var o,i=e.state;return i.window===null&&(i.wsize=1<<i.wbits,i.wnext=0,i.whave=0,i.window=on(i.wsize)),n>=i.wsize?(Nr(i.window,t,r-i.wsize,i.wsize,0),i.wnext=0,i.whave=i.wsize):(o=i.wsize-i.wnext,o>n&&(o=n),Nr(i.window,t,r-n,o,i.wnext),n-=o,n?(Nr(i.window,t,r-n,n,0),i.wnext=n,i.whave=i.wsize):(i.wnext+=o,i.wnext===i.wsize&&(i.wnext=0),i.whave<i.wsize&&(i.whave+=o))),0}function MI(e,t){var r,n,o,i,a,s,c,l,A,u,m,d,g,C,y=0,I,E,b,x,w,Q,S,k,N=on(4),_,v,L=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15];if(!e||!e.state||!e.output||!e.input&&e.avail_in!==0)return or;r=e.state,r.mode===an&&(r.mode=Mf),a=e.next_out,o=e.output,c=e.avail_out,i=e.next_in,n=e.input,s=e.avail_in,l=r.hold,A=r.bits,u=s,m=c,k=mo;e:for(;;)switch(r.mode){case SI:if(r.wrap===0){r.mode=Mf;break}for(;A<16;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}if(r.wrap&2&&l===35615){r.check=0,N[0]=l&255,N[1]=l>>>8&255,r.check=nr(r.check,N,2,0),l=0,A=0,r.mode=eI;break}if(r.flags=0,r.head&&(r.head.done=!1),!(r.wrap&1)||(((l&255)<<8)+(l>>8))%31){e.msg="incorrect header check",r.mode=Be;break}if((l&15)!==ZE){e.msg="unknown compression method",r.mode=Be;break}if(l>>>=4,A-=4,S=(l&15)+8,r.wbits===0)r.wbits=S;else if(S>r.wbits){e.msg="invalid window size",r.mode=Be;break}r.dmax=1<<S,e.adler=r.check=1,r.mode=l&512?cI:an,l=0,A=0;break;case eI:for(;A<16;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}if(r.flags=l,(r.flags&255)!==ZE){e.msg="unknown compression method",r.mode=Be;break}if(r.flags&57344){e.msg="unknown header flags set",r.mode=Be;break}r.head&&(r.head.text=l>>8&1),r.flags&512&&(N[0]=l&255,N[1]=l>>>8&255,r.check=nr(r.check,N,2,0)),l=0,A=0,r.mode=tI;case tI:for(;A<32;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}r.head&&(r.head.time=l),r.flags&512&&(N[0]=l&255,N[1]=l>>>8&255,N[2]=l>>>16&255,N[3]=l>>>24&255,r.check=nr(r.check,N,4,0)),l=0,A=0,r.mode=rI;case rI:for(;A<16;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}r.head&&(r.head.xflags=l&255,r.head.os=l>>8),r.flags&512&&(N[0]=l&255,N[1]=l>>>8&255,r.check=nr(r.check,N,2,0)),l=0,A=0,r.mode=nI;case nI:if(r.flags&1024){for(;A<16;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}r.length=l,r.head&&(r.head.extra_len=l),r.flags&512&&(N[0]=l&255,N[1]=l>>>8&255,r.check=nr(r.check,N,2,0)),l=0,A=0}else r.head&&(r.head.extra=null);r.mode=oI;case oI:if(r.flags&1024&&(d=r.length,d>s&&(d=s),d&&(r.head&&(S=r.head.extra_len-r.length,r.head.extra||(r.head.extra=new Array(r.head.extra_len)),Nr(r.head.extra,n,i,d,S)),r.flags&512&&(r.check=nr(r.check,n,d,i)),s-=d,i+=d,r.length-=d),r.length))break e;r.length=0,r.mode=iI;case iI:if(r.flags&2048){if(s===0)break e;d=0;do S=n[i+d++],r.head&&S&&r.length<65536&&(r.head.name+=String.fromCharCode(S));while(S&&d<s);if(r.flags&512&&(r.check=nr(r.check,n,d,i)),s-=d,i+=d,S)break e}else r.head&&(r.head.name=null);r.length=0,r.mode=aI;case aI:if(r.flags&4096){if(s===0)break e;d=0;do S=n[i+d++],r.head&&S&&r.length<65536&&(r.head.comment+=String.fromCharCode(S));while(S&&d<s);if(r.flags&512&&(r.check=nr(r.check,n,d,i)),s-=d,i+=d,S)break e}else r.head&&(r.head.comment=null);r.mode=sI;case sI:if(r.flags&512){for(;A<16;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}if(l!==(r.check&65535)){e.msg="header crc mismatch",r.mode=Be;break}l=0,A=0}r.head&&(r.head.hcrc=r.flags>>9&1,r.head.done=!0),e.adler=r.check=0,r.mode=an;break;case cI:for(;A<32;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}e.adler=r.check=xI(l),l=0,A=0,r.mode=Rc;case Rc:if(r.havedict===0)return e.next_out=a,e.avail_out=c,e.next_in=i,e.avail_in=s,r.hold=l,r.bits=A,Kk;e.adler=r.check=1,r.mode=an;case an:if(t===Wk||t===Dc)break e;case Mf:if(r.last){l>>>=A&7,A-=A&7,r.mode=Tf;break}for(;A<3;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}switch(r.last=l&1,l>>>=1,A-=1,l&3){case 0:r.mode=lI;break;case 1:if(aD(r),r.mode=Nc,t===Dc){l>>>=2,A-=2;break e}break;case 2:r.mode=uI;break;case 3:e.msg="invalid block type",r.mode=Be}l>>>=2,A-=2;break;case lI:for(l>>>=A&7,A-=A&7;A<32;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}if((l&65535)!==(l>>>16^65535)){e.msg="invalid stored block lengths",r.mode=Be;break}if(r.length=l&65535,l=0,A=0,r.mode=_f,t===Dc)break e;case _f:r.mode=AI;case AI:if(d=r.length,d){if(d>s&&(d=s),d>c&&(d=c),d===0)break e;Nr(o,n,i,d,a),s-=d,i+=d,c-=d,a+=d,r.length-=d;break}r.mode=an;break;case uI:for(;A<14;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}if(r.nlen=(l&31)+257,l>>>=5,A-=5,r.ndist=(l&31)+1,l>>>=5,A-=5,r.ncode=(l&15)+4,l>>>=4,A-=4,r.nlen>286||r.ndist>30){e.msg="too many length or distance symbols",r.mode=Be;break}r.have=0,r.mode=fI;case fI:for(;r.have<r.ncode;){for(;A<3;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}r.lens[L[r.have++]]=l&7,l>>>=3,A-=3}for(;r.have<19;)r.lens[L[r.have++]]=0;if(r.lencode=r.lendyn,r.lenbits=7,_={bits:r.lenbits},k=fo(zk,r.lens,0,19,r.lencode,0,r.work,_),r.lenbits=_.bits,k){e.msg="invalid code lengths set",r.mode=Be;break}r.have=0,r.mode=dI;case dI:for(;r.have<r.nlen+r.ndist;){for(;y=r.lencode[l&(1<<r.lenbits)-1],I=y>>>24,E=y>>>16&255,b=y&65535,!(I<=A);){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}if(b<16)l>>>=I,A-=I,r.lens[r.have++]=b;else{if(b===16){for(v=I+2;A<v;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}if(l>>>=I,A-=I,r.have===0){e.msg="invalid bit length repeat",r.mode=Be;break}S=r.lens[r.have-1],d=3+(l&3),l>>>=2,A-=2}else if(b===17){for(v=I+3;A<v;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}l>>>=I,A-=I,S=0,d=3+(l&7),l>>>=3,A-=3}else{for(v=I+7;A<v;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}l>>>=I,A-=I,S=0,d=11+(l&127),l>>>=7,A-=7}if(r.have+d>r.nlen+r.ndist){e.msg="invalid bit length repeat",r.mode=Be;break}for(;d--;)r.lens[r.have++]=S}}if(r.mode===Be)break;if(r.lens[256]===0){e.msg="invalid code -- missing end-of-block",r.mode=Be;break}if(r.lenbits=9,_={bits:r.lenbits},k=fo(wI,r.lens,0,r.nlen,r.lencode,0,r.work,_),r.lenbits=_.bits,k){e.msg="invalid literal/lengths set",r.mode=Be;break}if(r.distbits=6,r.distcode=r.distdyn,_={bits:r.distbits},k=fo(bI,r.lens,r.nlen,r.ndist,r.distcode,0,r.work,_),r.distbits=_.bits,k){e.msg="invalid distances set",r.mode=Be;break}if(r.mode=Nc,t===Dc)break e;case Nc:r.mode=Lc;case Lc:if(s>=6&&c>=258){e.next_out=a,e.avail_out=c,e.next_in=i,e.avail_in=s,r.hold=l,r.bits=A,Qf(e,m),a=e.next_out,o=e.output,c=e.avail_out,i=e.next_in,n=e.input,s=e.avail_in,l=r.hold,A=r.bits,r.mode===an&&(r.back=-1);break}for(r.back=0;y=r.lencode[l&(1<<r.lenbits)-1],I=y>>>24,E=y>>>16&255,b=y&65535,!(I<=A);){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}if(E&&(E&240)===0){for(x=I,w=E,Q=b;y=r.lencode[Q+((l&(1<<x+w)-1)>>x)],I=y>>>24,E=y>>>16&255,b=y&65535,!(x+I<=A);){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}l>>>=x,A-=x,r.back+=x}if(l>>>=I,A-=I,r.back+=I,r.length=b,E===0){r.mode=CI;break}if(E&32){r.back=-1,r.mode=an;break}if(E&64){e.msg="invalid literal/length code",r.mode=Be;break}r.extra=E&15,r.mode=mI;case mI:if(r.extra){for(v=r.extra;A<v;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}r.length+=l&(1<<r.extra)-1,l>>>=r.extra,A-=r.extra,r.back+=r.extra}r.was=r.length,r.mode=pI;case pI:for(;y=r.distcode[l&(1<<r.distbits)-1],I=y>>>24,E=y>>>16&255,b=y&65535,!(I<=A);){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}if((E&240)===0){for(x=I,w=E,Q=b;y=r.distcode[Q+((l&(1<<x+w)-1)>>x)],I=y>>>24,E=y>>>16&255,b=y&65535,!(x+I<=A);){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}l>>>=x,A-=x,r.back+=x}if(l>>>=I,A-=I,r.back+=I,E&64){e.msg="invalid distance code",r.mode=Be;break}r.offset=b,r.extra=E&15,r.mode=gI;case gI:if(r.extra){for(v=r.extra;A<v;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}r.offset+=l&(1<<r.extra)-1,l>>>=r.extra,A-=r.extra,r.back+=r.extra}if(r.offset>r.dmax){e.msg="invalid distance too far back",r.mode=Be;break}r.mode=hI;case hI:if(c===0)break e;if(d=m-c,r.offset>d){if(d=r.offset-d,d>r.whave&&r.sane){e.msg="invalid distance too far back",r.mode=Be;break}d>r.wnext?(d-=r.wnext,g=r.wsize-d):g=r.wnext-d,d>r.length&&(d=r.length),C=r.window}else C=o,g=a-r.offset,d=r.length;d>c&&(d=c),c-=d,r.length-=d;do o[a++]=C[g++];while(--d);r.length===0&&(r.mode=Lc);break;case CI:if(c===0)break e;o[a++]=r.length,c--,r.mode=Lc;break;case Tf:if(r.wrap){for(;A<32;){if(s===0)break e;s--,l|=n[i++]<<A,A+=8}if(m-=c,e.total_out+=m,r.total+=m,m&&(e.adler=r.check=r.flags?nr(r.check,o,m,a-m):Oa(r.check,o,m,a-m)),m=c,(r.flags?l:xI(l))!==r.check){e.msg="incorrect data check",r.mode=Be;break}l=0,A=0}r.mode=EI;case EI:if(r.wrap&&r.flags){for(;A<32;){if(s===0)break e;s--,l+=n[i++]<<A,A+=8}if(l!==(r.total&4294967295)){e.msg="incorrect length check",r.mode=Be;break}l=0,A=0}r.mode=II;case II:k=$k;break e;case Be:k=BI;break e;case Lf:return Nf;case Zk:default:return or}return e.next_out=a,e.avail_out=c,e.next_in=i,e.avail_in=s,r.hold=l,r.bits=A,(r.wsize||m!==e.avail_out&&r.mode<Be&&(r.mode<Tf||t!==XE))&&vI(e,e.output,e.next_out,m-e.avail_out)?(r.mode=Lf,Nf):(u-=e.avail_in,m-=e.avail_out,e.total_in+=u,e.total_out+=m,r.total+=m,r.wrap&&m&&(e.adler=r.check=r.flags?nr(r.check,o,m,e.next_out-m):Oa(r.check,o,m,e.next_out-m)),e.data_type=r.bits+(r.last?64:0)+(r.mode===an?128:0)+(r.mode===Nc||r.mode===_f?256:0),(u===0&&m===0||t===XE)&&k===mo&&(k=Xk),k)}function _I(e){if(!e||!e.state)return or;var t=e.state;return t.window&&(t.window=null),e.state=null,mo}function TI(e,t){var r;return!e||!e.state||(r=e.state,(r.wrap&2)===0)?or:(r.head=t,t.done=!1,mo)}function Rf(e,t){var r=t.length,n,o,i;return!e||!e.state||(n=e.state,n.wrap!==0&&n.mode!==Rc)?or:n.mode===Rc&&(o=1,o=Oa(o,t,r,0),o!==n.check)?BI:(i=vI(e,t,r,r),i?(n.mode=Lf,Nf):(n.havedict=1,mo))}var zk,wI,bI,XE,Wk,Dc,mo,$k,Kk,or,BI,Nf,Xk,ZE,SI,eI,tI,rI,nI,oI,iI,aI,sI,cI,Rc,an,Mf,lI,_f,AI,uI,fI,dI,Nc,Lc,mI,pI,gI,hI,CI,Tf,EI,II,Be,Lf,Zk,eD,tD,yI,kf,Df,kI=p(()=>{jE();JE();VE();KE();Pa();zk=0,wI=1,bI=2,XE=4,Wk=5,Dc=6,mo=0,$k=1,Kk=2,or=-2,BI=-3,Nf=-4,Xk=-5,ZE=8,SI=1,eI=2,tI=3,rI=4,nI=5,oI=6,iI=7,aI=8,sI=9,cI=10,Rc=11,an=12,Mf=13,lI=14,_f=15,AI=16,uI=17,fI=18,dI=19,Nc=20,Lc=21,mI=22,pI=23,gI=24,hI=25,CI=26,Tf=27,EI=28,II=29,Be=30,Lf=31,Zk=32,eD=852,tD=592;yI=!0});var Fc,DI=p(()=>{Fc={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible version"}});function Ff(){this.input=null,this.next_in=0,this.avail_in=0,this.total_in=0,this.output=null,this.next_out=0,this.avail_out=0,this.total_out=0,this.msg="",this.state=null,this.data_type=2,this.adler=0}var NI=p(()=>{});function sD(e,t){var r=new Of(t);if(r.push(e,!0),r.err)throw r.msg||Fc[r.err];return r.result}var Pf,Of,LI,RI=p(()=>{Pa();UE();wf();HE();kI();DI();NI();Pf=Object.prototype.toString,Of=class e{constructor(t){if(!(this instanceof e))return new e(t);this.options=LE({chunkSize:16384,windowBits:0,to:""},t||{});var r=this.options;r.raw&&r.windowBits>=0&&r.windowBits<16&&(r.windowBits=-r.windowBits,r.windowBits===0&&(r.windowBits=-15)),r.windowBits>=0&&r.windowBits<16&&!(t&&t.windowBits)&&(r.windowBits+=32),r.windowBits>15&&r.windowBits<48&&(r.windowBits&15)===0&&(r.windowBits|=15),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new Ff,this.strm.avail_out=0;var n=QI(this.strm,r.windowBits);if(n!==bn)throw new Error(Fc[n]);if(this.header=new Sf,TI(this.strm,this.header),r.dictionary&&(typeof r.dictionary=="string"?r.dictionary=Bf(r.dictionary):Pf.call(r.dictionary)==="[object ArrayBuffer]"&&(r.dictionary=new Uint8Array(r.dictionary)),r.raw&&(n=Rf(this.strm,r.dictionary),n!==bn)))throw new Error(Fc[n])}push(t,r){var n=this.strm,o=this.options.chunkSize,i=this.options.dictionary,a,s,c,l,A,u,m=!1;if(this.ended)return!1;s=r===~~r?r:r===!0?Na:xf,typeof t=="string"?n.input=PE(t):Pf.call(t)==="[object ArrayBuffer]"?n.input=new Uint8Array(t):n.input=t,n.next_in=0,n.avail_in=n.input.length;do{if(n.avail_out===0&&(n.output=on(o),n.next_out=0,n.avail_out=o),a=MI(n,xf),a===DE&&i&&(typeof i=="string"?u=Bf(i):Pf.call(i)==="[object ArrayBuffer]"?u=new Uint8Array(i):u=i,a=Rf(this.strm,u)),a===NE&&m===!0&&(a=bn,m=!1),a!==La&&a!==bn)return this.onEnd(a),this.ended=!0,!1;n.next_out&&(n.avail_out===0||a===La||n.avail_in===0&&(s===Na||s===yf))&&(this.options.to==="string"?(c=GE(n.output,n.next_out),l=n.next_out-c,A=OE(n.output,c),n.next_out=l,n.avail_out=o-l,l&&Nr(n.output,n.output,c,l,0),this.onData(A)):this.onData(Tc(n.output,n.next_out))),n.avail_in===0&&n.avail_out===0&&(m=!0)}while((n.avail_in>0||n.avail_out===0)&&a!==La);return a===La&&(s=Na),s===Na?(a=_I(this.strm),this.onEnd(a),this.ended=!0,a===bn):(s===yf&&(this.onEnd(bn),n.avail_out=0),!0)}onData(t){this.chunks.push(t)}onEnd(t){t===bn&&(this.options.to==="string"?this.result=this.chunks.join(""):this.result=_c(this.chunks)),this.chunks=[],this.err=t,this.msg=this.strm.msg}};LI=sD});var FI=p(()=>{});var PI=p(()=>{wf();RI();FI()});function UI(e){try{let a=le.__wbindgen_add_to_stack_pointer(-16),s=qI(e,le.__wbindgen_export2),c=qf;le.decompress_all(a,s,c);var t=jt().getInt32(a+0,!0),r=jt().getInt32(a+4,!0),n=jt().getInt32(a+8,!0),o=jt().getInt32(a+12,!0);if(o)throw JI(n);var i=HI(t,r).slice();return le.__wbindgen_export(t,r*1,1),i}finally{le.__wbindgen_add_to_stack_pointer(16)}}function lD(e,t,r,n,o){try{let c=le.__wbindgen_add_to_stack_pointer(-16),l=qI(e,le.__wbindgen_export2),A=qf;le.decompress_chunk_slice(c,l,A,t,r,n,o);var i=jt().getInt32(c+0,!0),a=jt().getInt32(c+4,!0),s=jt().getInt32(c+8,!0);if(s)throw JI(a);return bi.__wrap(i)}finally{le.__wbindgen_add_to_stack_pointer(16)}}function AD(e,t){let r=Error(jI(e,t));return fD(r)}function uD(e,t){throw new Error(jI(e,t))}function fD(e){Ua===sn.length&&sn.push(sn.length+1);let t=Ua;return Ua=sn[t],sn[t]=e,t}function dD(e){e<1028||(sn[e]=Ua,Ua=e)}function GI(e,t){return e=e>>>0,mD().subarray(e/8,e/8+t)}function HI(e,t){return e=e>>>0,jf().subarray(e/1,e/1+t)}function jt(){return(wi===null||wi.buffer.detached===!0||wi.buffer.detached===void 0&&wi.buffer!==le.memory.buffer)&&(wi=new DataView(le.memory.buffer)),wi}function mD(){return(Pc===null||Pc.byteLength===0)&&(Pc=new Float64Array(le.memory.buffer)),Pc}function jI(e,t){return hD(e>>>0,t)}function jf(){return(Oc===null||Oc.byteLength===0)&&(Oc=new Uint8Array(le.memory.buffer)),Oc}function pD(e){return sn[e]}function qI(e,t){let r=t(e.length*1,1)>>>0;return jf().set(e,r/1),qf=e.length,r}function JI(e){let t=pD(e);return dD(e),t}function hD(e,t){return Gf+=t,Gf>=gD&&(Gc=new TextDecoder("utf-8",{ignoreBOM:!0,fatal:!0}),Gc.decode(),Gf=t),Gc.decode(jf().subarray(e,e+t))}function VI(e){le=e}async function CD(){return Ga||(Uf||(Uf=(async()=>{let t=await(await fetch(cD)).arrayBuffer(),{instance:r}=await WebAssembly.instantiate(t,{"./bgzf_wasm_bg.js":Hf});return Ga=r.exports,VI(Ga),Ga})()),Uf)}async function YI(e){return await CD(),UI(e)}var po,Hf,cD,bi,OI,wi,Pc,Oc,sn,Ua,Gc,gD,Gf,qf,le,Ga,Uf,zI=p(()=>{po={};po.d=(e,t)=>{for(var r in t)po.o(t,r)&&!po.o(e,r)&&Object.defineProperty(e,r,{enumerable:!0,get:t[r]})};po.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t);po.r=e=>{typeof Symbol<"u"&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0})};Hf={};po.r(Hf);po.d(Hf,{ChunkSliceResult:()=>bi,__wbg_Error_ef53bc310eb298a0:()=>AD,__wbg___wbindgen_throw_1506f2235d1bdba0:()=>uD,__wbg_set_wasm:()=>VI,decompress_all:()=>UI,decompress_chunk_slice:()=>lD});cD="data:application/wasm;base64,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",bi=class e{static __wrap(t){let r=Object.create(e.prototype);return r.__wbg_ptr=t,OI.register(r,r.__wbg_ptr,r),r}__destroy_into_raw(){let t=this.__wbg_ptr;return this.__wbg_ptr=0,OI.unregister(this),t}free(){let t=this.__destroy_into_raw();le.__wbg_chunksliceresult_free(t,0)}take_buffer(){try{let o=le.__wbindgen_add_to_stack_pointer(-16);le.chunksliceresult_take_buffer(o,this.__wbg_ptr);var t=jt().getInt32(o+0,!0),r=jt().getInt32(o+4,!0),n=HI(t,r).slice();return le.__wbindgen_export(t,r*1,1),n}finally{le.__wbindgen_add_to_stack_pointer(16)}}take_cpositions(){try{let o=le.__wbindgen_add_to_stack_pointer(-16);le.chunksliceresult_take_cpositions(o,this.__wbg_ptr);var t=jt().getInt32(o+0,!0),r=jt().getInt32(o+4,!0),n=GI(t,r).slice();return le.__wbindgen_export(t,r*8,8),n}finally{le.__wbindgen_add_to_stack_pointer(16)}}take_dpositions(){try{let o=le.__wbindgen_add_to_stack_pointer(-16);le.chunksliceresult_take_dpositions(o,this.__wbg_ptr);var t=jt().getInt32(o+0,!0),r=jt().getInt32(o+4,!0),n=GI(t,r).slice();return le.__wbindgen_export(t,r*8,8),n}finally{le.__wbindgen_add_to_stack_pointer(16)}}};Symbol.dispose&&(bi.prototype[Symbol.dispose]=bi.prototype.free);OI=typeof FinalizationRegistry>"u"?{register:()=>{},unregister:()=>{}}:new FinalizationRegistry(e=>le.__wbg_chunksliceresult_free(e,1));wi=null;Pc=null;Oc=null;sn=new Array(1024).fill(void 0);sn.push(void 0,null,!0,!1);Ua=sn.length;Gc=new TextDecoder("utf-8",{ignoreBOM:!0,fatal:!0});Gc.decode();gD=2146435072,Gf=0;qf=0;Ga=null,Uf=null});function ED(e){return e[0]===31&&e[1]===139}function WI(e){return e instanceof Error?e.message:`${e}`}async function ID(e){if(typeof DecompressionStream<"u"){let t=new Blob([e]).stream().pipeThrough(new DecompressionStream("gzip"));return new Uint8Array(await new Response(t).arrayBuffer())}else return LI(e,void 0)}function xD(e){return WI(e).includes("invalid gzip header")?new Error("problem decompressing block: incorrect gzip header check",{cause:e}):e}async function Uc(e){try{return await YI(e)}catch(t){if(WI(t).includes("invalid bgzf header")){if(ED(e))return ID(e);throw new Error("problem decompressing block: not a valid bgzf or gzip block",{cause:t})}throw xD(t)}}var Jf=p(()=>{PI();zI()});function $I(e){let t=0;for(let o of e)t+=o.length;let r=new Uint8Array(t),n=0;for(let o of e)r.set(o,n),n+=o.length;return r}var KI=p(()=>{});function bD(e){let t=0,r=[],n=()=>{t--,r.shift()?.()};return async o=>{t>=e&&await new Promise(i=>{r.push(i)}),t++;try{return await o()}finally{n()}}}function BD(e,t,r,n){let o=Math.max(0,r-t),i=Math.min(n,t+e.length)-t;return o<e.length?e.subarray(o,i):new Uint8Array(0)}var yD,wD,Bi,XI=p(()=>{kE();Jf();KI();yD=10,wD=65536;Bi=class{filehandle;gzi;limit;constructor({filehandle:t,gziFilehandle:r,blockConcurrency:n=yD}){this.filehandle=t,this.gzi=new Da({filehandle:r}),this.limit=bD(n)}async _readAndUncompressBlock(t,r){let n=await this.filehandle.read(r,t);return Uc(n)}async read(t,r){let{blocks:n,nextCompressedPosition:o}=await this.gzi.getRelevantBlocksForRead(t,r);if(n.length===0)return new Uint8Array(0);let i=r+t,a=await Promise.all(n.map(([s,c],l)=>this.limit(async()=>{let A=n[l+1]?.[0]??o??s+wD,u=await this._readAndUncompressBlock(s,A-s);return BD(u,c,r,i)})));return $I(a)}}});var Vf=p(()=>{XI();Jf()});var ex=V((F6,ZI)=>{ZI.exports=JBrowseExports["react-dom"]});var rx=V((P6,tx)=>{tx.exports=JBrowseExports["react-dom/client"]});function nx(e){let t="",r=!1;for(let n=0,o=e.length;n<o;n++){let i=e[n];i==="<"?r=!0:i===">"?r=!1:r||(t+=i)}return t}var Yf=p(()=>{});var ox=p(()=>{});var ix=p(()=>{});var ax=p(()=>{});function Hc(e){return typeof e=="object"&&e!==null&&"uri"in e&&!!e.uri}var SD,zf=p(()=>{SD=f(Pt(),1);ax()});var QD,sx=p(()=>{QD=f(Vo(),1)});var cx=p(()=>{});var lx=p(()=>{});var Si,jc,Wf,$f,vD,Ha,qc,Ax=p(()=>{Si={METHOD:"method",PROPERTY:"property"},jc=class{constructor(t,r){this.inst=t,this.args=r}},Wf=class extends jc{constructor(t,r){super(t,r),this.type=Si.METHOD}execute(t){t[this.inst](...this.args)}},$f=class extends jc{constructor(t,r){super(t,r),this.type=Si.PROPERTY}execute(t){t[this.inst]=this.args[0]}},vD={[Si.METHOD]:Wf,[Si.PROPERTY]:$f},Ha=class{constructor(t,r,n){return new vD[t](r,n)}};Ha.METHOD=Si.METHOD;Ha.PROPERTY=Si.PROPERTY;qc=Ha});var ux,Lr,Jc,Kf=p(()=>{Ax();ux=Object.freeze({METHODS:["addHitRegion","arc","arcTo","beginPath","bezierCurveTo","clearHitRegions","clearRect","clip","closePath","drawFocusIfNeeded","drawImage","ellipse","fill","fillRect","fillText","lineTo","moveTo","putImageData","quadraticCurveTo","rect","removeHitRegion","resetTransform","restore","rotate","save","scale","scrollPathIntoView","setLineDash","setTransform","stroke","strokeRect","strokeText","transform","translate"],PROPERTIES:["direction","fillStyle","filter","font","globalAlpha","globalCompositeOperation","imageSmoothingEnabled","imageSmoothingQuality","lineCap","lineDashOffset","lineJoin","lineWidth","miterLimit","shadowBlur","shadowColor","shadowOffsetX","shadowOffsetY","strokeStyle","textAlign","textBaseline"]}),Lr=Object.freeze({sequence:Symbol.for("sequence"),push:Symbol.for("push"),fromJSON:Symbol.for("fromJSON")}),Jc=class{constructor(t=null){this[Lr.sequence]=[],t&&this[Lr.fromJSON](t)}[Lr.fromJSON](t={sequence:[]}){t.sequence.forEach(({type:r,inst:n,args:o})=>{this[Lr.push](r,n,o)})}[Lr.push](t,r,n){this[Lr.sequence].push(new qc(t,r,n))}execute(t){t.save(),this[Lr.sequence].forEach(r=>r.execute(t)),t.restore()}toJSON(){return{sequence:this[Lr.sequence]}}};ux.METHODS.forEach(e=>{Object.defineProperty(Jc.prototype,e,{value:function(...r){this[Lr.push](qc.METHOD,e,r)},writable:!1,enumerable:!0,configurable:!1})});ux.PROPERTIES.forEach(e=>{Object.defineProperty(Jc.prototype,e,{get(){throw`Invalid canvas sequencer interaction, cannot get ${e}.`},set(t){this[Lr.push](qc.PROPERTY,e,[t])},enumerable:!0,configurable:!1})})});var K6,dx=p(()=>{Kf();K6=Object.freeze({sequence:Symbol.for("sequence"),push:Symbol.for("push")})});var mx=p(()=>{dx();Kf()});var gx=V((nG,px)=>{px.exports=!1});var MD,hx=p(()=>{mx();MD=f(gx(),1)});var _D,TD,Cx=p(()=>{_D=f(R(),1),TD=f(M(),1)});var Ex=p(()=>{});var cG,lG,AG,uG,Ix=p(()=>{cG=new Uint8Array([99,124,119,123,242,107,111,197,48,1,103,43,254,215,171,118,202,130,201,125,250,89,71,240,173,212,162,175,156,164,114,192,183,253,147,38,54,63,247,204,52,165,229,241,113,216,49,21,4,199,35,195,24,150,5,154,7,18,128,226,235,39,178,117,9,131,44,26,27,110,90,160,82,59,214,179,41,227,47,132,83,209,0,237,32,252,177,91,106,203,190,57,74,76,88,207,208,239,170,251,67,77,51,133,69,249,2,127,80,60,159,168,81,163,64,143,146,157,56,245,188,182,218,33,16,255,243,210,205,12,19,236,95,151,68,23,196,167,126,61,100,93,25,115,96,129,79,220,34,42,144,136,70,238,184,20,222,94,11,219,224,50,58,10,73,6,36,92,194,211,172,98,145,149,228,121,231,200,55,109,141,213,78,169,108,86,244,234,101,122,174,8,186,120,37,46,28,166,180,198,232,221,116,31,75,189,139,138,112,62,181,102,72,3,246,14,97,53,87,185,134,193,29,158,225,248,152,17,105,217,142,148,155,30,135,233,206,85,40,223,140,161,137,13,191,230,66,104,65,153,45,15,176,84,187,22]),lG=new Uint8Array([82,9,106,213,48,54,165,56,191,64,163,158,129,243,215,251,124,227,57,130,155,47,255,135,52,142,67,68,196,222,233,203,84,123,148,50,166,194,35,61,238,76,149,11,66,250,195,78,8,46,161,102,40,217,36,178,118,91,162,73,109,139,209,37,114,248,246,100,134,104,152,22,212,164,92,204,93,101,182,146,108,112,72,80,253,237,185,218,94,21,70,87,167,141,157,132,144,216,171,0,140,188,211,10,247,228,88,5,184,179,69,6,208,44,30,143,202,63,15,2,193,175,189,3,1,19,138,107,58,145,17,65,79,103,220,234,151,242,207,206,240,180,230,115,150,172,116,34,231,173,53,133,226,249,55,232,28,117,223,110,71,241,26,113,29,41,197,137,111,183,98,14,170,24,190,27,252,86,62,75,198,210,121,32,154,219,192,254,120,205,90,244,31,221,168,51,136,7,199,49,177,18,16,89,39,128,236,95,96,81,127,169,25,181,74,13,45,229,122,159,147,201,156,239,160,224,59,77,174,42,245,176,200,235,187,60,131,83,153,97,23,43,4,126,186,119,214,38,225,105,20,99,85,33,12,125]),AG=new Uint8Array([1,2,4,8,16,32,64,128,27,54]),uG=new Uint32Array([1116352408,1899447441,3049323471,3921009573,961987163,1508970993,2453635748,2870763221,3624381080,310598401,607225278,1426881987,1925078388,2162078206,2614888103,3248222580,3835390401,4022224774,264347078,604807628,770255983,1249150122,1555081692,1996064986,2554220882,2821834349,2952996808,3210313671,3336571891,3584528711,113926993,338241895,666307205,773529912,1294757372,1396182291,1695183700,1986661051,2177026350,2456956037,2730485921,2820302411,3259730800,3345764771,3516065817,3600352804,4094571909,275423344,430227734,506948616,659060556,883997877,958139571,1322822218,1537002063,1747873779,1955562222,2024104815,2227730452,2361852424,2428436474,2756734187,3204031479,3329325298])});function ja(e,t){if(typeof t!="function"&&t!==null)throw new TypeError("Class extends value "+String(t)+" is not a constructor or null");Xf(e,t);function r(){this.constructor=e}e.prototype=t===null?Object.create(t):(r.prototype=t.prototype,new r)}function Zf(e){var t=typeof Symbol=="function"&&Symbol.iterator,r=t&&e[t],n=0;if(r)return r.call(e);if(e&&typeof e.length=="number")return{next:function(){return e&&n>=e.length&&(e=void 0),{value:e&&e[n++],done:!e}}};throw new TypeError(t?"Object is not iterable.":"Symbol.iterator is not defined.")}function Qi(e,t){var r=typeof Symbol=="function"&&e[Symbol.iterator];if(!r)return e;var n=r.call(e),o,i=[],a;try{for(;(t===void 0||t-- >0)&&!(o=n.next()).done;)i.push(o.value)}catch(s){a={error:s}}finally{try{o&&!o.done&&(r=n.return)&&r.call(n)}finally{if(a)throw a.error}}return i}function vi(e,t,r){if(r||arguments.length===2)for(var n=0,o=t.length,i;n<o;n++)(i||!(n in t))&&(i||(i=Array.prototype.slice.call(t,0,n)),i[n]=t[n]);return e.concat(i||Array.prototype.slice.call(t))}var Xf,qa=p(()=>{Xf=function(e,t){return Xf=Object.setPrototypeOf||{__proto__:[]}instanceof Array&&function(r,n){r.__proto__=n}||function(r,n){for(var o in n)Object.prototype.hasOwnProperty.call(n,o)&&(r[o]=n[o])},Xf(e,t)}});function Rr(e){return typeof e=="function"}var Vc=p(()=>{});function Yc(e){var t=function(n){Error.call(n),n.stack=new Error().stack},r=e(t);return r.prototype=Object.create(Error.prototype),r.prototype.constructor=r,r}var ed=p(()=>{});var zc,xx=p(()=>{ed();zc=Yc(function(e){return function(r){e(this),this.message=r?r.length+` errors occurred during unsubscription:
+      `} 1.2s infinite ease-in-out`}}})});var BS=z((sZ,SS)=>{SS.exports=function(){var e=document.getSelection();if(!e.rangeCount)return function(){};for(var t=document.activeElement,r=[],n=0;n<e.rangeCount;n++)r.push(e.getRangeAt(n));switch(t.tagName.toUpperCase()){case"INPUT":case"TEXTAREA":t.blur();break;default:t=null;break}return e.removeAllRanges(),function(){e.type==="Caret"&&e.removeAllRanges(),e.rangeCount||r.forEach(function(o){e.addRange(o)}),t&&t.focus()}}});var QS=z((cZ,TS)=>{"use strict";var $O=BS(),vS={"text/plain":"Text","text/html":"Url",default:"Text"},qO="Copy to clipboard: #{key}, Enter";function JO(e){var t=(/mac os x/i.test(navigator.userAgent)?"\u2318":"Ctrl")+"+C";return e.replace(/#{\s*key\s*}/g,t)}function WO(e,t){var r,n,o,i,a,s,c=!1;t||(t={}),r=t.debug||!1;try{o=$O(),i=document.createRange(),a=document.getSelection(),s=document.createElement("span"),s.textContent=e,s.ariaHidden="true",s.style.all="unset",s.style.position="fixed",s.style.top=0,s.style.clip="rect(0, 0, 0, 0)",s.style.whiteSpace="pre",s.style.webkitUserSelect="text",s.style.MozUserSelect="text",s.style.msUserSelect="text",s.style.userSelect="text",s.addEventListener("copy",function(u){if(u.stopPropagation(),t.format)if(u.preventDefault(),typeof u.clipboardData>"u"){r&&console.warn("unable to use e.clipboardData"),r&&console.warn("trying IE specific stuff"),window.clipboardData.clearData();var A=vS[t.format]||vS.default;window.clipboardData.setData(A,e)}else u.clipboardData.clearData(),u.clipboardData.setData(t.format,e);t.onCopy&&(u.preventDefault(),t.onCopy(u.clipboardData))}),document.body.appendChild(s),i.selectNodeContents(s),a.addRange(i);var l=document.execCommand("copy");if(!l)throw new Error("copy command was unsuccessful");c=!0}catch(u){r&&console.error("unable to copy using execCommand: ",u),r&&console.warn("trying IE specific stuff");try{window.clipboardData.setData(t.format||"text",e),t.onCopy&&t.onCopy(window.clipboardData),c=!0}catch(A){r&&console.error("unable to copy using clipboardData: ",A),r&&console.error("falling back to prompt"),n=JO("message"in t?t.message:qO),window.prompt(n,e)}}finally{a&&(typeof a.removeRange=="function"?a.removeRange(i):a.removeAllRanges()),s&&document.body.removeChild(s),o()}return c}TS.exports=WO});var NS={};bt(NS,{default:()=>DS});async function kS(e){let t=await fetch(e);if(!t.ok)throw new Error(`HTTP ${t.status} fetching ${e}: ${await t.text()}`);return t.text()}async function zO(e){return JSON.parse(await kS(e))}async function ZO(e){if(Kp[e])return Kp[e];let t=new URL(e).search,r=await kS(e),n=KO.exec(r)?.[1]??"",o=await zO(new URL(n,e).href+t),i=new _S.SourceMapConsumer(o);return Kp[e]=i,i}async function e4(e){let t=[];for(let r of e.split(`
+`)){let n=XO.exec(r);if(!n){t.push(r);continue}let o=n[2],a=(await ZO(o)).originalPositionFor({line:+n[3],column:+n[4]});if(!a.source||!a.line||!a.column){t.push(r);continue}t.push(`${a.source}:${a.line}:${a.column+1} (${n[1].trim()})`)}return t.join(`
+`)}function t4(e,t){return e.startsWith("Error:")?e.slice(`${t}`.length):e}function r4(e){return typeof e=="object"&&e!==null&&"stack"in e?`${e.stack}`:""}function DS({error:e,onClose:t,extra:r}){let[n,o]=(0,ka.useState)(),[i,a]=(0,ka.useState)(),[s,c]=(0,ka.useState)(!1),l=e?`${e}`:"",u=t4(r4(e),l);(0,ka.useEffect)(()=>{(async()=>{try{o(await e4(u))}catch(f){console.error(f),o(u),a(f)}})()},[u]);let A=window.JBrowseSession?.version,m=[i?"Error loading source map, showing raw stack trace below:":"",l.length>MS?`${l.slice(0,MS)}...`:l,n||"No stack trace available",A?`JBrowse ${A}`:""].filter(Boolean).join(`
+`);return(0,xr.jsxs)(er.Dialog,{open:!0,onClose:t,maxWidth:"xl",children:[(0,xr.jsxs)(er.DialogTitle,{children:["Stack trace",(0,xr.jsx)(er.IconButton,{onClick:t,sx:{position:"absolute",right:8,top:8},children:(0,xr.jsx)(Uu,{})})]}),(0,xr.jsx)(er.DialogContent,{children:n===void 0?(0,xr.jsx)(zp,{variant:"h6"}):(0,xr.jsx)(Wp,{text:m,extra:r})}),(0,xr.jsxs)(er.DialogActions,{children:[(0,xr.jsx)(er.Button,{variant:"contained",color:"secondary",onClick:async()=>{let{default:f}=await Promise.resolve().then(()=>p(QS(),1));f(m),c(!0),setTimeout(()=>{c(!1)},1e3)},children:s?"Copied!":"Copy stack trace to clipboard"}),(0,xr.jsx)(er.Button,{variant:"contained",color:"primary",onClick:t,children:"Close"})]})]})}var xr,ka,er,_S,Kp,KO,XO,MS,RS=d(()=>{xr=p(O(),1),ka=p(k(),1);Rp();er=p(V(),1),_S=p(mS(),1);ES();wS();Kp={},KO=/\/\/# sourceMappingURL=(.*)/,XO=/(.*)((?:https?|file):\/\/.*):(\d+):(\d+)/;MS=1e4});function o4(e){let t="",r="is not assignable",n=e.indexOf(r);if(n!==-1){let o=e.slice(0,n+r.length),i=/.*at path "(.*)" snapshot `(.*)` is not assignable/m.exec(o);i&&(e=`Failed to load element at ${i[1]}...Failed element had snapshot`,t=i[2]);let a=/.*snapshot `(.*)` is not assignable/.exec(o);a&&(e="Failed to load element...Failed element had snapshot",t=a[1])}return t}function i4({error:e,onReset:t}){let{classes:r}=LS(),[n,o]=(0,Na.useState)(!1);return(0,$t.jsxs)("div",{className:r.iconFloat,children:[typeof e=="object"&&e&&"stack"in e?(0,$t.jsx)(Da.Tooltip,{title:"Get stack trace",children:(0,$t.jsx)(Da.IconButton,{onClick:()=>{o(!0)},color:"primary",children:(0,$t.jsx)(Ow,{})})}):null,t?(0,$t.jsx)(Da.Tooltip,{title:"Retry",children:(0,$t.jsx)(Da.IconButton,{onClick:t,color:"primary",children:(0,$t.jsx)(Lw,{})})}):null,n?(0,$t.jsx)(Na.Suspense,{fallback:null,children:(0,$t.jsx)(n4,{error:e,onClose:()=>{o(!1)}})}):null]})}function a4({error:e,onReset:t}){let{classes:r}=LS(),n=`${e}`,o=n.indexOf("expected an instance of"),i=o!==-1?n.slice(0,o):n,a=o4(n);return(0,$t.jsxs)(Lp,{children:[i.slice(0,1e4),(0,$t.jsx)(i4,{error:e,onReset:t}),a?(0,$t.jsx)("pre",{className:r.bg,children:JSON.stringify(JSON.parse(a),null,2)}):null]})}var $t,Na,Da,n4,LS,FS,PS=d(()=>{$t=p(O(),1),Na=p(k(),1);Fw();Gw();Da=p(V(),1);Hw();$e();n4=(0,Na.lazy)(()=>Promise.resolve().then(()=>(RS(),NS))),LS=X()(e=>({bg:{background:e.palette.divider,border:"1px solid black",margin:20},iconFloat:{float:"right",marginLeft:100}}));FS=a4});var GS=z((hZ,OS)=>{"use strict";var s4=/["'&<>]/;OS.exports=c4;function c4(e){var t=""+e,r=s4.exec(t);if(!r)return t;var n,o="",i=0,a=0;for(i=r.index;i<t.length;i++){switch(t.charCodeAt(i)){case 34:n="&quot;";break;case 38:n="&amp;";break;case 39:n="&#39;";break;case 60:n="&lt;";break;case 62:n="&gt;";break;default:continue}a!==i&&(o+=t.substring(a,i)),a=i+1,o+=n}return a!==i?o+t.substring(a,i):o}});function zu(e,t=0){let r=e.getUint32(t,!0);return e.getUint32(t+4,!0)*4294967296+r}var US=d(()=>{});function l4(e,t){let r=new Array(t+1);r[0]=[0,0];let n=new DataView(e.buffer,e.byteOffset,e.byteLength);for(let o=0;o<t;o+=1){let i=o*Xp;r[o+1]=[zu(n,i),zu(n,i+8)]}return r}function u4(e,t){let r=0,n=e.length;for(;r<n;){let o=r+n>>>1;e[o][1]<=t?r=o+1:n=o}return r}var Xp,gc,HS=d(()=>{US();Xp=16;gc=class{filehandle;index;constructor({filehandle:t}){this.filehandle=t}_getIndex(){return this.index||(this.index=this._readIndex().catch(t=>{throw this.index=void 0,t})),this.index}async _readIndex(){let t=await this.filehandle.read(8,0),r=zu(new DataView(t.buffer,t.byteOffset,t.byteLength));if(r===0)return[[0,0]];if(r>Number.MAX_SAFE_INTEGER/Xp)throw new TypeError("integer overflow");let n=await this.filehandle.read(Xp*r,8);return l4(n,r)}async getRelevantBlocksForRead(t,r){if(t===0)return{blocks:[],nextCompressedPosition:void 0};let n=await this._getIndex(),o=r+t,i=u4(n,r)-1,a=i+1;for(;a<n.length&&n[a][1]<o;)a+=1;return{blocks:n.slice(i,a),nextCompressedPosition:n[a]?.[0]}}}});var Zp,eg,hc,lo,Cc,VS,jS,tg=d(()=>{Zp=0,eg=2,hc=4,lo=0,Cc=1,VS=2,jS=-5});function f4(e,t){return Object.prototype.hasOwnProperty.call(e,t)}function YS(e){for(var t=Array.prototype.slice.call(arguments,1);t.length;){var r=t.shift();if(r){if(typeof r!="object")throw new TypeError(r+"must be non-object");for(var n in r)f4(r,n)&&(e[n]=r[n])}}return e}function Xu(e,t){return e.length===t?e:e.subarray?e.subarray(0,t):(e.length=t,e)}var yc,xc,Ra,fn,Ku,Gn,uo,si,Ec=d(()=>{yc={arraySet:function(e,t,r,n,o){if(t.subarray&&e.subarray){e.set(t.subarray(r,r+n),o);return}for(var i=0;i<n;i++)e[o+i]=t[r+i]},flattenChunks:function(e){var t,r,n,o,i,a;for(n=0,t=0,r=e.length;t<r;t++)n+=e[t].length;for(a=new Uint8Array(n),o=0,t=0,r=e.length;t<r;t++)i=e[t],a.set(i,o),o+=i.length;return a},Buf8:function(e){return new Uint8Array(e)},Buf16:function(e){return new Uint16Array(e)},Buf32:function(e){return new Int32Array(e)}},xc={arraySet:function(e,t,r,n,o){for(var i=0;i<n;i++)e[o+i]=t[r+i]},flattenChunks:function(e){return[].concat.apply([],e)},Buf8:function(e){return new Array(e)},Buf16:function(e){return new Array(e)},Buf32:function(e){return new Array(e)}},Ra=()=>{let e=typeof Uint8Array<"u"&&typeof Uint16Array<"u"&&typeof Int32Array<"u";return Ra=()=>e,e},fn=(e,t,r,n,o)=>(fn=Ra()?yc.arraySet:xc.arraySet,fn(e,t,r,n,o)),Ku=e=>(Ku=Ra()?yc.flattenChunks:xc.flattenChunks,Ku(e)),Gn=e=>(Gn=Ra()?yc.Buf8:xc.Buf8,Gn(e)),uo=e=>(uo=Ra()?yc.Buf16:xc.Buf16,uo(e)),si=e=>(si=Ra()?yc.Buf32:xc.Buf32,si(e))});function ng(e){var t,r,n,o,i,a=e.length,s=0;for(o=0;o<a;o++)r=e.charCodeAt(o),(r&64512)===55296&&o+1<a&&(n=e.charCodeAt(o+1),(n&64512)===56320&&(r=65536+(r-55296<<10)+(n-56320),o++)),s+=r<128?1:r<2048?2:r<65536?3:4;for(t=new Uint8Array(s),i=0,o=0;i<s;o++)r=e.charCodeAt(o),(r&64512)===55296&&o+1<a&&(n=e.charCodeAt(o+1),(n&64512)===56320&&(r=65536+(r-55296<<10)+(n-56320),o++)),r<128?t[i++]=r:r<2048?(t[i++]=192|r>>>6,t[i++]=128|r&63):r<65536?(t[i++]=224|r>>>12,t[i++]=128|r>>>6&63,t[i++]=128|r&63):(t[i++]=240|r>>>18,t[i++]=128|r>>>12&63,t[i++]=128|r>>>6&63,t[i++]=128|r&63);return t}function A4(e,t){if(t<65534&&(e.subarray&&qS()||!e.subarray&&$S()))return String.fromCharCode.apply(null,Xu(e,t));for(var r="",n=0;n<t;n++)r+=String.fromCharCode(e[n]);return r}function JS(e){for(var t=new Uint8Array(e.length),r=0,n=t.length;r<n;r++)t[r]=e.charCodeAt(r);return t}function WS(e,t){var r,n,o,i,a=t||e.length,s=new Array(a*2);for(n=0,r=0;r<a;){if(o=e[r++],o<128){s[n++]=o;continue}if(i=rg(o),i>4){s[n++]=65533,r+=i-1;continue}for(o&=i===2?31:i===3?15:7;i>1&&r<a;)o=o<<6|e[r++]&63,i--;if(i>1){s[n++]=65533;continue}o<65536?s[n++]=o:(o-=65536,s[n++]=55296|o>>10&1023,s[n++]=56320|o&1023)}return A4(s,n)}function zS(e,t){var r;for(t=t||e.length,t>e.length&&(t=e.length),r=t-1;r>=0&&(e[r]&192)===128;)r--;return r<0||r===0?t:r+rg(e[r])>t?r:t}var $S,qS,rg,KS=d(()=>{Ec();$S=function(){let e=!0;try{String.fromCharCode.apply(null,[0])}catch{e=!1}return $S=()=>e,e},qS=function(){let e=!0;try{String.fromCharCode.apply(null,new Uint8Array(1))}catch{e=!1}return qS=()=>e,e},rg=function(e){for(var t=Gn(256),r=0;r<256;r++)t[r]=r>=252?6:r>=248?5:r>=240?4:r>=224?3:r>=192?2:1;return t[254]=t[254]=1,rg=n=>t[n],t[e]}});function og(){this.text=0,this.time=0,this.xflags=0,this.os=0,this.extra=null,this.extra_len=0,this.name="",this.comment="",this.hcrc=0,this.done=!1}var XS=d(()=>{});function bc(e,t,r,n){for(var o=e&65535|0,i=e>>>16&65535|0,a=0;r!==0;){a=r>2e3?2e3:r,r-=a;do o=o+t[n++]|0,i=i+o|0;while(--a);o%=65521,i%=65521}return o|i<<16|0}var ZS=d(()=>{});function d4(){for(var e,t=[],r=0;r<256;r++){e=r;for(var n=0;n<8;n++)e=e&1?3988292384^e>>>1:e>>>1;t[r]=e}return t}function Er(e,t,r,n){var o=e1(),i=n+r;e^=-1;for(var a=n;a<i;a++)e=e>>>8^o[(e^t[a])&255];return e^-1}var e1,t1=d(()=>{e1=function(){let e=d4();return e1=()=>e,e}});function ig(e,t){var r,n,o,i,a,s,c,l,u,A,m,f,g,y,E,b,x,B,I,w,S,v,D,N,L;r=e.state,n=e.next_in,N=e.input,o=n+(e.avail_in-5),i=e.next_out,L=e.output,a=i-(t-e.avail_out),s=i+(e.avail_out-257),c=r.dmax,l=r.wsize,u=r.whave,A=r.wnext,m=r.window,f=r.hold,g=r.bits,y=r.lencode,E=r.distcode,b=(1<<r.lenbits)-1,x=(1<<r.distbits)-1;e:do{g<15&&(f+=N[n++]<<g,g+=8,f+=N[n++]<<g,g+=8),B=y[f&b];t:for(;;){if(I=B>>>24,f>>>=I,g-=I,I=B>>>16&255,I===0)L[i++]=B&65535;else if(I&16){w=B&65535,I&=15,I&&(g<I&&(f+=N[n++]<<g,g+=8),w+=f&(1<<I)-1,f>>>=I,g-=I),g<15&&(f+=N[n++]<<g,g+=8,f+=N[n++]<<g,g+=8),B=E[f&x];r:for(;;){if(I=B>>>24,f>>>=I,g-=I,I=B>>>16&255,I&16){if(S=B&65535,I&=15,g<I&&(f+=N[n++]<<g,g+=8,g<I&&(f+=N[n++]<<g,g+=8)),S+=f&(1<<I)-1,S>c){e.msg="invalid distance too far back",r.mode=Zu;break e}if(f>>>=I,g-=I,I=i-a,S>I){if(I=S-I,I>u&&r.sane){e.msg="invalid distance too far back",r.mode=Zu;break e}if(v=0,D=m,A===0){if(v+=l-I,I<w){w-=I;do L[i++]=m[v++];while(--I);v=i-S,D=L}}else if(A<I){if(v+=l+A-I,I-=A,I<w){w-=I;do L[i++]=m[v++];while(--I);if(v=0,A<w){I=A,w-=I;do L[i++]=m[v++];while(--I);v=i-S,D=L}}}else if(v+=A-I,I<w){w-=I;do L[i++]=m[v++];while(--I);v=i-S,D=L}for(;w>2;)L[i++]=D[v++],L[i++]=D[v++],L[i++]=D[v++],w-=3;w&&(L[i++]=D[v++],w>1&&(L[i++]=D[v++]))}else{v=i-S;do L[i++]=L[v++],L[i++]=L[v++],L[i++]=L[v++],w-=3;while(w>2);w&&(L[i++]=L[v++],w>1&&(L[i++]=L[v++]))}}else if((I&64)===0){B=E[(B&65535)+(f&(1<<I)-1)];continue r}else{e.msg="invalid distance code",r.mode=Zu;break e}break}}else if((I&64)===0){B=y[(B&65535)+(f&(1<<I)-1)];continue t}else if(I&32){r.mode=m4;break e}else{e.msg="invalid literal/length code",r.mode=Zu;break e}break}}while(n<o&&i<s);w=g>>3,n-=w,g-=w<<3,f&=(1<<g)-1,e.next_in=n,e.next_out=i,e.avail_in=n<o?5+(o-n):5-(n-o),e.avail_out=i<s?257+(s-i):257-(i-s),r.hold=f,r.bits=g}var Zu,m4,r1=d(()=>{Zu=30,m4=12});function ci(e,t,r,n,o,i,a,s){var c=s.bits,l=0,u=0,A=0,m=0,f=0,g=0,y=0,E=0,b=0,x=0,B,I,w,S,v,D=null,N=0,L,P=uo(La+1),h=uo(La+1),Q=null,_=0,G,q,oe;for(l=0;l<=La;l++)P[l]=0;for(u=0;u<n;u++)P[t[r+u]]++;for(f=c,m=La;m>=1&&P[m]===0;m--);if(f>m&&(f=m),m===0)return o[i++]=1<<24|64<<16|0,o[i++]=1<<24|64<<16|0,s.bits=1,0;for(A=1;A<m&&P[A]===0;A++);for(f<A&&(f=A),E=1,l=1;l<=La;l++)if(E<<=1,E-=P[l],E<0)return-1;if(E>0&&(e===i1||m!==1))return-1;for(h[1]=0,l=1;l<La;l++)h[l+1]=h[l]+P[l];for(u=0;u<n;u++)t[r+u]!==0&&(a[h[t[r+u]]++]=u);if(e===i1?(D=Q=a,L=19):e===ag?(D=p4,N-=257,Q=g4,_-=257,L=256):(D=h4,Q=C4,L=-1),x=0,u=0,l=A,v=i,g=f,y=0,w=-1,b=1<<f,S=b-1,e===ag&&b>n1||e===a1&&b>o1)return 1;for(;;){G=l-y,a[u]<L?(q=0,oe=a[u]):a[u]>L?(q=Q[_+a[u]],oe=D[N+a[u]]):(q=96,oe=0),B=1<<l-y,I=1<<g,A=I;do I-=B,o[v+(x>>y)+I]=G<<24|q<<16|oe|0;while(I!==0);for(B=1<<l-1;x&B;)B>>=1;if(B!==0?(x&=B-1,x+=B):x=0,u++,--P[l]===0){if(l===m)break;l=t[r+a[u]]}if(l>f&&(x&S)!==w){for(y===0&&(y=f),v+=A,g=l-y,E=1<<g;g+y<m&&(E-=P[g+y],!(E<=0));)g++,E<<=1;if(b+=1<<g,e===ag&&b>n1||e===a1&&b>o1)return 1;w=x&S,o[w]=f<<24|g<<16|v-i|0}}return x!==0&&(o[v+x]=l-y<<24|64<<16|0),s.bits=f,0}var La,n1,o1,i1,ag,a1,p4,g4,h4,C4,s1=d(()=>{Ec();La=15,n1=852,o1=592,i1=0,ag=1,a1=2,p4=[3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0],g4=[16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78],h4=[1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0],C4=[16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64]});function _1(e){return(e>>>24&255)+(e>>>8&65280)+((e&65280)<<8)+((e&255)<<24)}function v4(){this.mode=0,this.last=!1,this.wrap=0,this.havedict=!1,this.flags=0,this.dmax=0,this.check=0,this.total=0,this.head=null,this.wbits=0,this.wsize=0,this.whave=0,this.wnext=0,this.window=null,this.hold=0,this.bits=0,this.length=0,this.offset=0,this.extra=0,this.lencode=null,this.distcode=null,this.lenbits=0,this.distbits=0,this.ncode=0,this.nlen=0,this.ndist=0,this.have=0,this.next=null,this.lens=uo(320),this.work=uo(288),this.lendyn=null,this.distdyn=null,this.sane=0,this.back=0,this.was=0}function T4(e){var t;return!e||!e.state?br:(t=e.state,e.total_in=e.total_out=t.total=0,e.msg="",t.wrap&&(e.adler=t.wrap&1),t.mode=L1,t.last=0,t.havedict=0,t.dmax=32768,t.head=null,t.hold=0,t.bits=0,t.lencode=t.lendyn=si(S4),t.distcode=t.distdyn=si(B4),t.sane=1,t.back=-1,li)}function Q4(e){var t;return!e||!e.state?br:(t=e.state,t.wsize=0,t.whave=0,t.wnext=0,T4(e))}function M4(e,t){var r,n;return!e||!e.state||(n=e.state,t<0?(r=0,t=-t):(r=(t>>4)+1,t<48&&(t&=15)),t&&(t<8||t>15))?br:(n.window!==null&&n.wbits!==t&&(n.window=null),n.wrap=r,n.wbits=t,Q4(e))}function F1(e,t){var r,n;return e?(n=new v4,e.state=n,n.window=null,r=M4(e,t),r!==li&&(e.state=null),r):br}function _4(e){if(k1){var t;for(ug=si(512),fg=si(32),t=0;t<144;)e.lens[t++]=8;for(;t<256;)e.lens[t++]=9;for(;t<280;)e.lens[t++]=7;for(;t<288;)e.lens[t++]=8;for(ci(D1,e.lens,0,288,ug,0,e.work,{bits:9}),t=0;t<32;)e.lens[t++]=5;ci(N1,e.lens,0,32,fg,0,e.work,{bits:5}),k1=!1}e.lencode=ug,e.lenbits=9,e.distcode=fg,e.distbits=5}function P1(e,t,r,n){var o,i=e.state;return i.window===null&&(i.wsize=1<<i.wbits,i.wnext=0,i.whave=0,i.window=Gn(i.wsize)),n>=i.wsize?(fn(i.window,t,r-i.wsize,i.wsize,0),i.wnext=0,i.whave=i.wsize):(o=i.wsize-i.wnext,o>n&&(o=n),fn(i.window,t,r-n,o,i.wnext),n-=o,n?(fn(i.window,t,r-n,n,0),i.wnext=n,i.whave=i.wsize):(i.wnext+=o,i.wnext===i.wsize&&(i.wnext=0),i.whave<i.wsize&&(i.whave+=o))),0}function O1(e,t){var r,n,o,i,a,s,c,l,u,A,m,f,g,y,E=0,b,x,B,I,w,S,v,D,N=Gn(4),L,P,h=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15];if(!e||!e.state||!e.output||!e.input&&e.avail_in!==0)return br;r=e.state,r.mode===Un&&(r.mode=sg),a=e.next_out,o=e.output,c=e.avail_out,i=e.next_in,n=e.input,s=e.avail_in,l=r.hold,u=r.bits,A=s,m=c,D=li;e:for(;;)switch(r.mode){case L1:if(r.wrap===0){r.mode=sg;break}for(;u<16;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}if(r.wrap&2&&l===35615){r.check=0,N[0]=l&255,N[1]=l>>>8&255,r.check=Er(r.check,N,2,0),l=0,u=0,r.mode=u1;break}if(r.flags=0,r.head&&(r.head.done=!1),!(r.wrap&1)||(((l&255)<<8)+(l>>8))%31){e.msg="incorrect header check",r.mode=Ne;break}if((l&15)!==l1){e.msg="unknown compression method",r.mode=Ne;break}if(l>>>=4,u-=4,v=(l&15)+8,r.wbits===0)r.wbits=v;else if(v>r.wbits){e.msg="invalid window size",r.mode=Ne;break}r.dmax=1<<v,e.adler=r.check=1,r.mode=l&512?C1:Un,l=0,u=0;break;case u1:for(;u<16;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}if(r.flags=l,(r.flags&255)!==l1){e.msg="unknown compression method",r.mode=Ne;break}if(r.flags&57344){e.msg="unknown header flags set",r.mode=Ne;break}r.head&&(r.head.text=l>>8&1),r.flags&512&&(N[0]=l&255,N[1]=l>>>8&255,r.check=Er(r.check,N,2,0)),l=0,u=0,r.mode=f1;case f1:for(;u<32;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}r.head&&(r.head.time=l),r.flags&512&&(N[0]=l&255,N[1]=l>>>8&255,N[2]=l>>>16&255,N[3]=l>>>24&255,r.check=Er(r.check,N,4,0)),l=0,u=0,r.mode=A1;case A1:for(;u<16;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}r.head&&(r.head.xflags=l&255,r.head.os=l>>8),r.flags&512&&(N[0]=l&255,N[1]=l>>>8&255,r.check=Er(r.check,N,2,0)),l=0,u=0,r.mode=d1;case d1:if(r.flags&1024){for(;u<16;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}r.length=l,r.head&&(r.head.extra_len=l),r.flags&512&&(N[0]=l&255,N[1]=l>>>8&255,r.check=Er(r.check,N,2,0)),l=0,u=0}else r.head&&(r.head.extra=null);r.mode=m1;case m1:if(r.flags&1024&&(f=r.length,f>s&&(f=s),f&&(r.head&&(v=r.head.extra_len-r.length,r.head.extra||(r.head.extra=new Array(r.head.extra_len)),fn(r.head.extra,n,i,f,v)),r.flags&512&&(r.check=Er(r.check,n,f,i)),s-=f,i+=f,r.length-=f),r.length))break e;r.length=0,r.mode=p1;case p1:if(r.flags&2048){if(s===0)break e;f=0;do v=n[i+f++],r.head&&v&&r.length<65536&&(r.head.name+=String.fromCharCode(v));while(v&&f<s);if(r.flags&512&&(r.check=Er(r.check,n,f,i)),s-=f,i+=f,v)break e}else r.head&&(r.head.name=null);r.length=0,r.mode=g1;case g1:if(r.flags&4096){if(s===0)break e;f=0;do v=n[i+f++],r.head&&v&&r.length<65536&&(r.head.comment+=String.fromCharCode(v));while(v&&f<s);if(r.flags&512&&(r.check=Er(r.check,n,f,i)),s-=f,i+=f,v)break e}else r.head&&(r.head.comment=null);r.mode=h1;case h1:if(r.flags&512){for(;u<16;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}if(l!==(r.check&65535)){e.msg="header crc mismatch",r.mode=Ne;break}l=0,u=0}r.head&&(r.head.hcrc=r.flags>>9&1,r.head.done=!0),e.adler=r.check=0,r.mode=Un;break;case C1:for(;u<32;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}e.adler=r.check=_1(l),l=0,u=0,r.mode=nf;case nf:if(r.havedict===0)return e.next_out=a,e.avail_out=c,e.next_in=i,e.avail_in=s,r.hold=l,r.bits=u,b4;e.adler=r.check=1,r.mode=Un;case Un:if(t===x4||t===ef)break e;case sg:if(r.last){l>>>=u&7,u-=u&7,r.mode=lg;break}for(;u<3;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}switch(r.last=l&1,l>>>=1,u-=1,l&3){case 0:r.mode=y1;break;case 1:if(_4(r),r.mode=tf,t===ef){l>>>=2,u-=2;break e}break;case 2:r.mode=E1;break;case 3:e.msg="invalid block type",r.mode=Ne}l>>>=2,u-=2;break;case y1:for(l>>>=u&7,u-=u&7;u<32;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}if((l&65535)!==(l>>>16^65535)){e.msg="invalid stored block lengths",r.mode=Ne;break}if(r.length=l&65535,l=0,u=0,r.mode=cg,t===ef)break e;case cg:r.mode=x1;case x1:if(f=r.length,f){if(f>s&&(f=s),f>c&&(f=c),f===0)break e;fn(o,n,i,f,a),s-=f,i+=f,c-=f,a+=f,r.length-=f;break}r.mode=Un;break;case E1:for(;u<14;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}if(r.nlen=(l&31)+257,l>>>=5,u-=5,r.ndist=(l&31)+1,l>>>=5,u-=5,r.ncode=(l&15)+4,l>>>=4,u-=4,r.nlen>286||r.ndist>30){e.msg="too many length or distance symbols",r.mode=Ne;break}r.have=0,r.mode=b1;case b1:for(;r.have<r.ncode;){for(;u<3;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}r.lens[h[r.have++]]=l&7,l>>>=3,u-=3}for(;r.have<19;)r.lens[h[r.have++]]=0;if(r.lencode=r.lendyn,r.lenbits=7,L={bits:r.lenbits},D=ci(y4,r.lens,0,19,r.lencode,0,r.work,L),r.lenbits=L.bits,D){e.msg="invalid code lengths set",r.mode=Ne;break}r.have=0,r.mode=I1;case I1:for(;r.have<r.nlen+r.ndist;){for(;E=r.lencode[l&(1<<r.lenbits)-1],b=E>>>24,x=E>>>16&255,B=E&65535,!(b<=u);){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}if(B<16)l>>>=b,u-=b,r.lens[r.have++]=B;else{if(B===16){for(P=b+2;u<P;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}if(l>>>=b,u-=b,r.have===0){e.msg="invalid bit length repeat",r.mode=Ne;break}v=r.lens[r.have-1],f=3+(l&3),l>>>=2,u-=2}else if(B===17){for(P=b+3;u<P;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}l>>>=b,u-=b,v=0,f=3+(l&7),l>>>=3,u-=3}else{for(P=b+7;u<P;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}l>>>=b,u-=b,v=0,f=11+(l&127),l>>>=7,u-=7}if(r.have+f>r.nlen+r.ndist){e.msg="invalid bit length repeat",r.mode=Ne;break}for(;f--;)r.lens[r.have++]=v}}if(r.mode===Ne)break;if(r.lens[256]===0){e.msg="invalid code -- missing end-of-block",r.mode=Ne;break}if(r.lenbits=9,L={bits:r.lenbits},D=ci(D1,r.lens,0,r.nlen,r.lencode,0,r.work,L),r.lenbits=L.bits,D){e.msg="invalid literal/lengths set",r.mode=Ne;break}if(r.distbits=6,r.distcode=r.distdyn,L={bits:r.distbits},D=ci(N1,r.lens,r.nlen,r.ndist,r.distcode,0,r.work,L),r.distbits=L.bits,D){e.msg="invalid distances set",r.mode=Ne;break}if(r.mode=tf,t===ef)break e;case tf:r.mode=rf;case rf:if(s>=6&&c>=258){e.next_out=a,e.avail_out=c,e.next_in=i,e.avail_in=s,r.hold=l,r.bits=u,ig(e,m),a=e.next_out,o=e.output,c=e.avail_out,i=e.next_in,n=e.input,s=e.avail_in,l=r.hold,u=r.bits,r.mode===Un&&(r.back=-1);break}for(r.back=0;E=r.lencode[l&(1<<r.lenbits)-1],b=E>>>24,x=E>>>16&255,B=E&65535,!(b<=u);){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}if(x&&(x&240)===0){for(I=b,w=x,S=B;E=r.lencode[S+((l&(1<<I+w)-1)>>I)],b=E>>>24,x=E>>>16&255,B=E&65535,!(I+b<=u);){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}l>>>=I,u-=I,r.back+=I}if(l>>>=b,u-=b,r.back+=b,r.length=B,x===0){r.mode=T1;break}if(x&32){r.back=-1,r.mode=Un;break}if(x&64){e.msg="invalid literal/length code",r.mode=Ne;break}r.extra=x&15,r.mode=w1;case w1:if(r.extra){for(P=r.extra;u<P;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}r.length+=l&(1<<r.extra)-1,l>>>=r.extra,u-=r.extra,r.back+=r.extra}r.was=r.length,r.mode=S1;case S1:for(;E=r.distcode[l&(1<<r.distbits)-1],b=E>>>24,x=E>>>16&255,B=E&65535,!(b<=u);){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}if((x&240)===0){for(I=b,w=x,S=B;E=r.distcode[S+((l&(1<<I+w)-1)>>I)],b=E>>>24,x=E>>>16&255,B=E&65535,!(I+b<=u);){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}l>>>=I,u-=I,r.back+=I}if(l>>>=b,u-=b,r.back+=b,x&64){e.msg="invalid distance code",r.mode=Ne;break}r.offset=B,r.extra=x&15,r.mode=B1;case B1:if(r.extra){for(P=r.extra;u<P;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}r.offset+=l&(1<<r.extra)-1,l>>>=r.extra,u-=r.extra,r.back+=r.extra}if(r.offset>r.dmax){e.msg="invalid distance too far back",r.mode=Ne;break}r.mode=v1;case v1:if(c===0)break e;if(f=m-c,r.offset>f){if(f=r.offset-f,f>r.whave&&r.sane){e.msg="invalid distance too far back",r.mode=Ne;break}f>r.wnext?(f-=r.wnext,g=r.wsize-f):g=r.wnext-f,f>r.length&&(f=r.length),y=r.window}else y=o,g=a-r.offset,f=r.length;f>c&&(f=c),c-=f,r.length-=f;do o[a++]=y[g++];while(--f);r.length===0&&(r.mode=rf);break;case T1:if(c===0)break e;o[a++]=r.length,c--,r.mode=rf;break;case lg:if(r.wrap){for(;u<32;){if(s===0)break e;s--,l|=n[i++]<<u,u+=8}if(m-=c,e.total_out+=m,r.total+=m,m&&(e.adler=r.check=r.flags?Er(r.check,o,m,a-m):bc(r.check,o,m,a-m)),m=c,(r.flags?l:_1(l))!==r.check){e.msg="incorrect data check",r.mode=Ne;break}l=0,u=0}r.mode=Q1;case Q1:if(r.wrap&&r.flags){for(;u<32;){if(s===0)break e;s--,l+=n[i++]<<u,u+=8}if(l!==(r.total&4294967295)){e.msg="incorrect length check",r.mode=Ne;break}l=0,u=0}r.mode=M1;case M1:D=E4;break e;case Ne:D=R1;break e;case dg:return Ag;case w4:default:return br}return e.next_out=a,e.avail_out=c,e.next_in=i,e.avail_in=s,r.hold=l,r.bits=u,(r.wsize||m!==e.avail_out&&r.mode<Ne&&(r.mode<lg||t!==c1))&&P1(e,e.output,e.next_out,m-e.avail_out)?(r.mode=dg,Ag):(A-=e.avail_in,m-=e.avail_out,e.total_in+=A,e.total_out+=m,r.total+=m,r.wrap&&m&&(e.adler=r.check=r.flags?Er(r.check,o,m,e.next_out-m):bc(r.check,o,m,e.next_out-m)),e.data_type=r.bits+(r.last?64:0)+(r.mode===Un?128:0)+(r.mode===tf||r.mode===cg?256:0),(A===0&&m===0||t===c1)&&D===li&&(D=I4),D)}function G1(e){if(!e||!e.state)return br;var t=e.state;return t.window&&(t.window=null),e.state=null,li}function U1(e,t){var r;return!e||!e.state||(r=e.state,(r.wrap&2)===0)?br:(r.head=t,t.done=!1,li)}function mg(e,t){var r=t.length,n,o,i;return!e||!e.state||(n=e.state,n.wrap!==0&&n.mode!==nf)?br:n.mode===nf&&(o=1,o=bc(o,t,r,0),o!==n.check)?R1:(i=P1(e,t,r,r),i?(n.mode=dg,Ag):(n.havedict=1,li))}var y4,D1,N1,c1,x4,ef,li,E4,b4,br,R1,Ag,I4,l1,L1,u1,f1,A1,d1,m1,p1,g1,h1,C1,nf,Un,sg,y1,cg,x1,E1,b1,I1,tf,rf,w1,S1,B1,v1,T1,lg,Q1,M1,Ne,dg,w4,S4,B4,k1,ug,fg,H1=d(()=>{ZS();t1();r1();s1();Ec();y4=0,D1=1,N1=2,c1=4,x4=5,ef=6,li=0,E4=1,b4=2,br=-2,R1=-3,Ag=-4,I4=-5,l1=8,L1=1,u1=2,f1=3,A1=4,d1=5,m1=6,p1=7,g1=8,h1=9,C1=10,nf=11,Un=12,sg=13,y1=14,cg=15,x1=16,E1=17,b1=18,I1=19,tf=20,rf=21,w1=22,S1=23,B1=24,v1=25,T1=26,lg=27,Q1=28,M1=29,Ne=30,dg=31,w4=32,S4=852,B4=592;k1=!0});var of,V1=d(()=>{of={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible version"}});function pg(){this.input=null,this.next_in=0,this.avail_in=0,this.total_in=0,this.output=null,this.next_out=0,this.avail_out=0,this.total_out=0,this.msg="",this.state=null,this.data_type=2,this.adler=0}var j1=d(()=>{});function k4(e,t){var r=new hg(t);if(r.push(e,!0),r.err)throw r.msg||of[r.err];return r.result}var gg,hg,Y1,$1=d(()=>{Ec();KS();tg();XS();H1();V1();j1();gg=Object.prototype.toString,hg=class e{constructor(t){if(!(this instanceof e))return new e(t);this.options=YS({chunkSize:16384,windowBits:0,to:""},t||{});var r=this.options;r.raw&&r.windowBits>=0&&r.windowBits<16&&(r.windowBits=-r.windowBits,r.windowBits===0&&(r.windowBits=-15)),r.windowBits>=0&&r.windowBits<16&&!(t&&t.windowBits)&&(r.windowBits+=32),r.windowBits>15&&r.windowBits<48&&(r.windowBits&15)===0&&(r.windowBits|=15),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new pg,this.strm.avail_out=0;var n=F1(this.strm,r.windowBits);if(n!==lo)throw new Error(of[n]);if(this.header=new og,U1(this.strm,this.header),r.dictionary&&(typeof r.dictionary=="string"?r.dictionary=ng(r.dictionary):gg.call(r.dictionary)==="[object ArrayBuffer]"&&(r.dictionary=new Uint8Array(r.dictionary)),r.raw&&(n=mg(this.strm,r.dictionary),n!==lo)))throw new Error(of[n])}push(t,r){var n=this.strm,o=this.options.chunkSize,i=this.options.dictionary,a,s,c,l,u,A,m=!1;if(this.ended)return!1;s=r===~~r?r:r===!0?hc:Zp,typeof t=="string"?n.input=JS(t):gg.call(t)==="[object ArrayBuffer]"?n.input=new Uint8Array(t):n.input=t,n.next_in=0,n.avail_in=n.input.length;do{if(n.avail_out===0&&(n.output=Gn(o),n.next_out=0,n.avail_out=o),a=O1(n,Zp),a===VS&&i&&(typeof i=="string"?A=ng(i):gg.call(i)==="[object ArrayBuffer]"?A=new Uint8Array(i):A=i,a=mg(this.strm,A)),a===jS&&m===!0&&(a=lo,m=!1),a!==Cc&&a!==lo)return this.onEnd(a),this.ended=!0,!1;n.next_out&&(n.avail_out===0||a===Cc||n.avail_in===0&&(s===hc||s===eg))&&(this.options.to==="string"?(c=zS(n.output,n.next_out),l=n.next_out-c,u=WS(n.output,c),n.next_out=l,n.avail_out=o-l,l&&fn(n.output,n.output,c,l,0),this.onData(u)):this.onData(Xu(n.output,n.next_out))),n.avail_in===0&&n.avail_out===0&&(m=!0)}while((n.avail_in>0||n.avail_out===0)&&a!==Cc);return a===Cc&&(s=hc),s===hc?(a=G1(this.strm),this.onEnd(a),this.ended=!0,a===lo):(s===eg&&(this.onEnd(lo),n.avail_out=0),!0)}onData(t){this.chunks.push(t)}onEnd(t){t===lo&&(this.options.to==="string"?this.result=this.chunks.join(""):this.result=Ku(this.chunks)),this.chunks=[],this.err=t,this.msg=this.strm.msg}};Y1=k4});var q1=d(()=>{});var J1=d(()=>{tg();$1();q1()});function K1(e){try{let a=he.__wbindgen_add_to_stack_pointer(-16),s=eB(e,he.__wbindgen_export2),c=bg;he.decompress_all(a,s,c);var t=tr().getInt32(a+0,!0),r=tr().getInt32(a+4,!0),n=tr().getInt32(a+8,!0),o=tr().getInt32(a+12,!0);if(o)throw tB(n);var i=X1(t,r).slice();return he.__wbindgen_export(t,r*1,1),i}finally{he.__wbindgen_add_to_stack_pointer(16)}}function N4(e,t,r,n,o){try{let c=he.__wbindgen_add_to_stack_pointer(-16),l=eB(e,he.__wbindgen_export2),u=bg;he.decompress_chunk_slice(c,l,u,t,r,n,o);var i=tr().getInt32(c+0,!0),a=tr().getInt32(c+4,!0),s=tr().getInt32(c+8,!0);if(s)throw tB(a);return Pa.__wrap(i)}finally{he.__wbindgen_add_to_stack_pointer(16)}}function R4(e,t){let r=Error(Z1(e,t));return F4(r)}function L4(e,t){throw new Error(Z1(e,t))}function F4(e){wc===Hn.length&&Hn.push(Hn.length+1);let t=wc;return wc=Hn[t],Hn[t]=e,t}function P4(e){e<1028||(Hn[e]=wc,wc=e)}function z1(e,t){return e=e>>>0,O4().subarray(e/8,e/8+t)}function X1(e,t){return e=e>>>0,Eg().subarray(e/1,e/1+t)}function tr(){return(Fa===null||Fa.buffer.detached===!0||Fa.buffer.detached===void 0&&Fa.buffer!==he.memory.buffer)&&(Fa=new DataView(he.memory.buffer)),Fa}function O4(){return(af===null||af.byteLength===0)&&(af=new Float64Array(he.memory.buffer)),af}function Z1(e,t){return H4(e>>>0,t)}function Eg(){return(sf===null||sf.byteLength===0)&&(sf=new Uint8Array(he.memory.buffer)),sf}function G4(e){return Hn[e]}function eB(e,t){let r=t(e.length*1,1)>>>0;return Eg().set(e,r/1),bg=e.length,r}function tB(e){let t=G4(e);return P4(e),t}function H4(e,t){return Cg+=t,Cg>=U4&&(cf=new TextDecoder("utf-8",{ignoreBOM:!0,fatal:!0}),cf.decode(),Cg=t),cf.decode(Eg().subarray(e,e+t))}function rB(e){he=e}async function V4(){return Ic||(yg||(yg=(async()=>{let t=await(await fetch(D4)).arrayBuffer(),{instance:r}=await WebAssembly.instantiate(t,{"./bgzf_wasm_bg.js":xg});return Ic=r.exports,rB(Ic),Ic})()),yg)}async function nB(e){return await V4(),K1(e)}var ui,xg,D4,Pa,W1,Fa,af,sf,Hn,wc,cf,U4,Cg,bg,he,Ic,yg,oB=d(()=>{ui={};ui.d=(e,t)=>{for(var r in t)ui.o(t,r)&&!ui.o(e,r)&&Object.defineProperty(e,r,{enumerable:!0,get:t[r]})};ui.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t);ui.r=e=>{typeof Symbol<"u"&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0})};xg={};ui.r(xg);ui.d(xg,{ChunkSliceResult:()=>Pa,__wbg_Error_ef53bc310eb298a0:()=>R4,__wbg___wbindgen_throw_1506f2235d1bdba0:()=>L4,__wbg_set_wasm:()=>rB,decompress_all:()=>K1,decompress_chunk_slice:()=>N4});D4="data:application/wasm;base64,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",Pa=class e{static __wrap(t){let r=Object.create(e.prototype);return r.__wbg_ptr=t,W1.register(r,r.__wbg_ptr,r),r}__destroy_into_raw(){let t=this.__wbg_ptr;return this.__wbg_ptr=0,W1.unregister(this),t}free(){let t=this.__destroy_into_raw();he.__wbg_chunksliceresult_free(t,0)}take_buffer(){try{let o=he.__wbindgen_add_to_stack_pointer(-16);he.chunksliceresult_take_buffer(o,this.__wbg_ptr);var t=tr().getInt32(o+0,!0),r=tr().getInt32(o+4,!0),n=X1(t,r).slice();return he.__wbindgen_export(t,r*1,1),n}finally{he.__wbindgen_add_to_stack_pointer(16)}}take_cpositions(){try{let o=he.__wbindgen_add_to_stack_pointer(-16);he.chunksliceresult_take_cpositions(o,this.__wbg_ptr);var t=tr().getInt32(o+0,!0),r=tr().getInt32(o+4,!0),n=z1(t,r).slice();return he.__wbindgen_export(t,r*8,8),n}finally{he.__wbindgen_add_to_stack_pointer(16)}}take_dpositions(){try{let o=he.__wbindgen_add_to_stack_pointer(-16);he.chunksliceresult_take_dpositions(o,this.__wbg_ptr);var t=tr().getInt32(o+0,!0),r=tr().getInt32(o+4,!0),n=z1(t,r).slice();return he.__wbindgen_export(t,r*8,8),n}finally{he.__wbindgen_add_to_stack_pointer(16)}}};Symbol.dispose&&(Pa.prototype[Symbol.dispose]=Pa.prototype.free);W1=typeof FinalizationRegistry>"u"?{register:()=>{},unregister:()=>{}}:new FinalizationRegistry(e=>he.__wbg_chunksliceresult_free(e,1));Fa=null;af=null;sf=null;Hn=new Array(1024).fill(void 0);Hn.push(void 0,null,!0,!1);wc=Hn.length;cf=new TextDecoder("utf-8",{ignoreBOM:!0,fatal:!0});cf.decode();U4=2146435072,Cg=0;bg=0;Ic=null,yg=null});function j4(e){return e[0]===31&&e[1]===139}function iB(e){return e instanceof Error?e.message:`${e}`}async function Y4(e){if(typeof DecompressionStream<"u"){let t=new Blob([e]).stream().pipeThrough(new DecompressionStream("gzip"));return new Uint8Array(await new Response(t).arrayBuffer())}else return Y1(e,void 0)}function $4(e){return iB(e).includes("invalid gzip header")?new Error("problem decompressing block: incorrect gzip header check",{cause:e}):e}async function lf(e){try{return await nB(e)}catch(t){if(iB(t).includes("invalid bgzf header")){if(j4(e))return Y4(e);throw new Error("problem decompressing block: not a valid bgzf or gzip block",{cause:t})}throw $4(t)}}var Ig=d(()=>{J1();oB()});function aB(e){let t=0;for(let o of e)t+=o.length;let r=new Uint8Array(t),n=0;for(let o of e)r.set(o,n),n+=o.length;return r}var sB=d(()=>{});function W4(e){let t=0,r=[],n=()=>{t--,r.shift()?.()};return async o=>{t>=e&&await new Promise(i=>{r.push(i)}),t++;try{return await o()}finally{n()}}}function z4(e,t,r,n){let o=Math.max(0,r-t),i=Math.min(n,t+e.length)-t;return o<e.length?e.subarray(o,i):new Uint8Array(0)}var q4,J4,Oa,cB=d(()=>{HS();Ig();sB();q4=10,J4=65536;Oa=class{filehandle;gzi;limit;constructor({filehandle:t,gziFilehandle:r,blockConcurrency:n=q4}){this.filehandle=t,this.gzi=new gc({filehandle:r}),this.limit=W4(n)}async _readAndUncompressBlock(t,r){let n=await this.filehandle.read(r,t);return lf(n)}async read(t,r){let{blocks:n,nextCompressedPosition:o}=await this.gzi.getRelevantBlocksForRead(t,r);if(n.length===0)return new Uint8Array(0);let i=r+t,a=await Promise.all(n.map(([s,c],l)=>this.limit(async()=>{let u=n[l+1]?.[0]??o??s+J4,A=await this._readAndUncompressBlock(s,u-s);return z4(A,c,r,i)})));return aB(a)}}});var wg=d(()=>{cB();Ig()});var uB=z((Aee,lB)=>{lB.exports=JBrowseExports["react-dom"]});var AB=z((dee,fB)=>{fB.exports=JBrowseExports["react-dom/client"]});function dB(e){let t="",r=!1;for(let n=0,o=e.length;n<o;n++){let i=e[n];i==="<"?r=!0:i===">"?r=!1:r||(t+=i)}return t}var Sg=d(()=>{});var mB=d(()=>{});var pB=d(()=>{});var gB=d(()=>{});function uf(e){return typeof e=="object"&&e!==null&&"uri"in e&&!!e.uri}var K4,Bg=d(()=>{K4=p(Vt(),1);gB()});var X4,hB=d(()=>{X4=p(Ca(),1)});var CB=d(()=>{});var yB=d(()=>{});var Ga,ff,vg,Tg,Z4,Sc,Af,xB=d(()=>{Ga={METHOD:"method",PROPERTY:"property"},ff=class{constructor(t,r){this.inst=t,this.args=r}},vg=class extends ff{constructor(t,r){super(t,r),this.type=Ga.METHOD}execute(t){t[this.inst](...this.args)}},Tg=class extends ff{constructor(t,r){super(t,r),this.type=Ga.PROPERTY}execute(t){t[this.inst]=this.args[0]}},Z4={[Ga.METHOD]:vg,[Ga.PROPERTY]:Tg},Sc=class{constructor(t,r,n){return new Z4[t](r,n)}};Sc.METHOD=Ga.METHOD;Sc.PROPERTY=Ga.PROPERTY;Af=Sc});var EB,An,df,Qg=d(()=>{xB();EB=Object.freeze({METHODS:["addHitRegion","arc","arcTo","beginPath","bezierCurveTo","clearHitRegions","clearRect","clip","closePath","drawFocusIfNeeded","drawImage","ellipse","fill","fillRect","fillText","lineTo","moveTo","putImageData","quadraticCurveTo","rect","removeHitRegion","resetTransform","restore","rotate","save","scale","scrollPathIntoView","setLineDash","setTransform","stroke","strokeRect","strokeText","transform","translate"],PROPERTIES:["direction","fillStyle","filter","font","globalAlpha","globalCompositeOperation","imageSmoothingEnabled","imageSmoothingQuality","lineCap","lineDashOffset","lineJoin","lineWidth","miterLimit","shadowBlur","shadowColor","shadowOffsetX","shadowOffsetY","strokeStyle","textAlign","textBaseline"]}),An=Object.freeze({sequence:Symbol.for("sequence"),push:Symbol.for("push"),fromJSON:Symbol.for("fromJSON")}),df=class{constructor(t=null){this[An.sequence]=[],t&&this[An.fromJSON](t)}[An.fromJSON](t={sequence:[]}){t.sequence.forEach(({type:r,inst:n,args:o})=>{this[An.push](r,n,o)})}[An.push](t,r,n){this[An.sequence].push(new Af(t,r,n))}execute(t){t.save(),this[An.sequence].forEach(r=>r.execute(t)),t.restore()}toJSON(){return{sequence:this[An.sequence]}}};EB.METHODS.forEach(e=>{Object.defineProperty(df.prototype,e,{value:function(...r){this[An.push](Af.METHOD,e,r)},writable:!1,enumerable:!0,configurable:!1})});EB.PROPERTIES.forEach(e=>{Object.defineProperty(df.prototype,e,{get(){throw`Invalid canvas sequencer interaction, cannot get ${e}.`},set(t){this[An.push](Af.PROPERTY,e,[t])},enumerable:!0,configurable:!1})})});var Bee,IB=d(()=>{Qg();Bee=Object.freeze({sequence:Symbol.for("sequence"),push:Symbol.for("push")})});var wB=d(()=>{IB();Qg()});var BB=z((kee,SB)=>{SB.exports=!1});var e8,vB=d(()=>{wB();e8=p(BB(),1)});var t8,r8,TB=d(()=>{t8=p(O(),1),r8=p(k(),1)});var QB=d(()=>{});var Fee,Pee,Oee,Gee,MB=d(()=>{Fee=new Uint8Array([99,124,119,123,242,107,111,197,48,1,103,43,254,215,171,118,202,130,201,125,250,89,71,240,173,212,162,175,156,164,114,192,183,253,147,38,54,63,247,204,52,165,229,241,113,216,49,21,4,199,35,195,24,150,5,154,7,18,128,226,235,39,178,117,9,131,44,26,27,110,90,160,82,59,214,179,41,227,47,132,83,209,0,237,32,252,177,91,106,203,190,57,74,76,88,207,208,239,170,251,67,77,51,133,69,249,2,127,80,60,159,168,81,163,64,143,146,157,56,245,188,182,218,33,16,255,243,210,205,12,19,236,95,151,68,23,196,167,126,61,100,93,25,115,96,129,79,220,34,42,144,136,70,238,184,20,222,94,11,219,224,50,58,10,73,6,36,92,194,211,172,98,145,149,228,121,231,200,55,109,141,213,78,169,108,86,244,234,101,122,174,8,186,120,37,46,28,166,180,198,232,221,116,31,75,189,139,138,112,62,181,102,72,3,246,14,97,53,87,185,134,193,29,158,225,248,152,17,105,217,142,148,155,30,135,233,206,85,40,223,140,161,137,13,191,230,66,104,65,153,45,15,176,84,187,22]),Pee=new Uint8Array([82,9,106,213,48,54,165,56,191,64,163,158,129,243,215,251,124,227,57,130,155,47,255,135,52,142,67,68,196,222,233,203,84,123,148,50,166,194,35,61,238,76,149,11,66,250,195,78,8,46,161,102,40,217,36,178,118,91,162,73,109,139,209,37,114,248,246,100,134,104,152,22,212,164,92,204,93,101,182,146,108,112,72,80,253,237,185,218,94,21,70,87,167,141,157,132,144,216,171,0,140,188,211,10,247,228,88,5,184,179,69,6,208,44,30,143,202,63,15,2,193,175,189,3,1,19,138,107,58,145,17,65,79,103,220,234,151,242,207,206,240,180,230,115,150,172,116,34,231,173,53,133,226,249,55,232,28,117,223,110,71,241,26,113,29,41,197,137,111,183,98,14,170,24,190,27,252,86,62,75,198,210,121,32,154,219,192,254,120,205,90,244,31,221,168,51,136,7,199,49,177,18,16,89,39,128,236,95,96,81,127,169,25,181,74,13,45,229,122,159,147,201,156,239,160,224,59,77,174,42,245,176,200,235,187,60,131,83,153,97,23,43,4,126,186,119,214,38,225,105,20,99,85,33,12,125]),Oee=new Uint8Array([1,2,4,8,16,32,64,128,27,54]),Gee=new Uint32Array([1116352408,1899447441,3049323471,3921009573,961987163,1508970993,2453635748,2870763221,3624381080,310598401,607225278,1426881987,1925078388,2162078206,2614888103,3248222580,3835390401,4022224774,264347078,604807628,770255983,1249150122,1555081692,1996064986,2554220882,2821834349,2952996808,3210313671,3336571891,3584528711,113926993,338241895,666307205,773529912,1294757372,1396182291,1695183700,1986661051,2177026350,2456956037,2730485921,2820302411,3259730800,3345764771,3516065817,3600352804,4094571909,275423344,430227734,506948616,659060556,883997877,958139571,1322822218,1537002063,1747873779,1955562222,2024104815,2227730452,2361852424,2428436474,2756734187,3204031479,3329325298])});function Bc(e,t){if(typeof t!="function"&&t!==null)throw new TypeError("Class extends value "+String(t)+" is not a constructor or null");Mg(e,t);function r(){this.constructor=e}e.prototype=t===null?Object.create(t):(r.prototype=t.prototype,new r)}function _g(e){var t=typeof Symbol=="function"&&Symbol.iterator,r=t&&e[t],n=0;if(r)return r.call(e);if(e&&typeof e.length=="number")return{next:function(){return e&&n>=e.length&&(e=void 0),{value:e&&e[n++],done:!e}}};throw new TypeError(t?"Object is not iterable.":"Symbol.iterator is not defined.")}function Ua(e,t){var r=typeof Symbol=="function"&&e[Symbol.iterator];if(!r)return e;var n=r.call(e),o,i=[],a;try{for(;(t===void 0||t-- >0)&&!(o=n.next()).done;)i.push(o.value)}catch(s){a={error:s}}finally{try{o&&!o.done&&(r=n.return)&&r.call(n)}finally{if(a)throw a.error}}return i}function Ha(e,t,r){if(r||arguments.length===2)for(var n=0,o=t.length,i;n<o;n++)(i||!(n in t))&&(i||(i=Array.prototype.slice.call(t,0,n)),i[n]=t[n]);return e.concat(i||Array.prototype.slice.call(t))}var Mg,vc=d(()=>{Mg=function(e,t){return Mg=Object.setPrototypeOf||{__proto__:[]}instanceof Array&&function(r,n){r.__proto__=n}||function(r,n){for(var o in n)Object.prototype.hasOwnProperty.call(n,o)&&(r[o]=n[o])},Mg(e,t)}});function dn(e){return typeof e=="function"}var mf=d(()=>{});function pf(e){var t=function(n){Error.call(n),n.stack=new Error().stack},r=e(t);return r.prototype=Object.create(Error.prototype),r.prototype.constructor=r,r}var kg=d(()=>{});var gf,_B=d(()=>{kg();gf=pf(function(e){return function(r){e(this),this.message=r?r.length+` errors occurred during unsubscription:
 `+r.map(function(n,o){return o+1+") "+n.toString()}).join(`
-  `):"",this.name="UnsubscriptionError",this.errors=r}})});function td(e,t){if(e){var r=e.indexOf(t);0<=r&&e.splice(r,1)}}var yx=p(()=>{});function bx(e){return e instanceof Wc||e&&"closed"in e&&Rr(e.remove)&&Rr(e.add)&&Rr(e.unsubscribe)}function wx(e){Rr(e)?e():e.unsubscribe()}var Wc,wG,Bx=p(()=>{qa();Vc();xx();yx();Wc=(function(){function e(t){this.initialTeardown=t,this.closed=!1,this._parentage=null,this._finalizers=null}return e.prototype.unsubscribe=function(){var t,r,n,o,i;if(!this.closed){this.closed=!0;var a=this._parentage;if(a)if(this._parentage=null,Array.isArray(a))try{for(var s=Zf(a),c=s.next();!c.done;c=s.next()){var l=c.value;l.remove(this)}}catch(C){t={error:C}}finally{try{c&&!c.done&&(r=s.return)&&r.call(s)}finally{if(t)throw t.error}}else a.remove(this);var A=this.initialTeardown;if(Rr(A))try{A()}catch(C){i=C instanceof zc?C.errors:[C]}var u=this._finalizers;if(u){this._finalizers=null;try{for(var m=Zf(u),d=m.next();!d.done;d=m.next()){var g=d.value;try{wx(g)}catch(C){i=i??[],C instanceof zc?i=vi(vi([],Qi(i)),Qi(C.errors)):i.push(C)}}}catch(C){n={error:C}}finally{try{d&&!d.done&&(o=m.return)&&o.call(m)}finally{if(n)throw n.error}}}if(i)throw new zc(i)}},e.prototype.add=function(t){var r;if(t&&t!==this)if(this.closed)wx(t);else{if(t instanceof e){if(t.closed||t._hasParent(this))return;t._addParent(this)}(this._finalizers=(r=this._finalizers)!==null&&r!==void 0?r:[]).push(t)}},e.prototype._hasParent=function(t){var r=this._parentage;return r===t||Array.isArray(r)&&r.includes(t)},e.prototype._addParent=function(t){var r=this._parentage;this._parentage=Array.isArray(r)?(r.push(t),r):r?[r,t]:t},e.prototype._removeParent=function(t){var r=this._parentage;r===t?this._parentage=null:Array.isArray(r)&&td(r,t)},e.prototype.remove=function(t){var r=this._finalizers;r&&td(r,t),t instanceof e&&t._removeParent(this)},e.EMPTY=(function(){var t=new e;return t.closed=!0,t})(),e})(),wG=Wc.EMPTY});var Sn,$c=p(()=>{Sn={onUnhandledError:null,onStoppedNotification:null,Promise:void 0,useDeprecatedSynchronousErrorHandling:!1,useDeprecatedNextContext:!1}});var Mi,rd=p(()=>{qa();Mi={setTimeout:function(e,t){for(var r=[],n=2;n<arguments.length;n++)r[n-2]=arguments[n];var o=Mi.delegate;return o?.setTimeout?o.setTimeout.apply(o,vi([e,t],Qi(r))):setTimeout.apply(void 0,vi([e,t],Qi(r)))},clearTimeout:function(e){var t=Mi.delegate;return(t?.clearTimeout||clearTimeout)(e)},delegate:void 0}});function Sx(e){Mi.setTimeout(function(){var t=Sn.onUnhandledError;if(t)t(e);else throw e})}var Qx=p(()=>{$c();rd()});function nd(){}var vx=p(()=>{});function _x(e){return od("E",void 0,e)}function Tx(e){return od("N",e,void 0)}function od(e,t,r){return{kind:e,value:t,error:r}}var Mx,kx=p(()=>{Mx=(function(){return od("C",void 0,void 0)})()});function Dx(e){Sn.useDeprecatedSynchronousErrorHandling&&id&&(id.errorThrown=!0,id.error=e)}var id,Nx=p(()=>{$c();id=null});function ad(e,t){return kD.call(e,t)}function Kc(e){Sn.useDeprecatedSynchronousErrorHandling?Dx(e):Sx(e)}function ND(e){throw e}function sd(e,t){var r=Sn.onStoppedNotification;r&&Mi.setTimeout(function(){return r(e,t)})}var cd,kD,DD,ld,LD,Ad=p(()=>{qa();Vc();Bx();$c();Qx();vx();kx();rd();Nx();cd=(function(e){ja(t,e);function t(r){var n=e.call(this)||this;return n.isStopped=!1,r?(n.destination=r,bx(r)&&r.add(n)):n.destination=LD,n}return t.create=function(r,n,o){return new ld(r,n,o)},t.prototype.next=function(r){this.isStopped?sd(Tx(r),this):this._next(r)},t.prototype.error=function(r){this.isStopped?sd(_x(r),this):(this.isStopped=!0,this._error(r))},t.prototype.complete=function(){this.isStopped?sd(Mx,this):(this.isStopped=!0,this._complete())},t.prototype.unsubscribe=function(){this.closed||(this.isStopped=!0,e.prototype.unsubscribe.call(this),this.destination=null)},t.prototype._next=function(r){this.destination.next(r)},t.prototype._error=function(r){try{this.destination.error(r)}finally{this.unsubscribe()}},t.prototype._complete=function(){try{this.destination.complete()}finally{this.unsubscribe()}},t})(Wc),kD=Function.prototype.bind;DD=(function(){function e(t){this.partialObserver=t}return e.prototype.next=function(t){var r=this.partialObserver;if(r.next)try{r.next(t)}catch(n){Kc(n)}},e.prototype.error=function(t){var r=this.partialObserver;if(r.error)try{r.error(t)}catch(n){Kc(n)}else Kc(t)},e.prototype.complete=function(){var t=this.partialObserver;if(t.complete)try{t.complete()}catch(r){Kc(r)}},e})(),ld=(function(e){ja(t,e);function t(r,n,o){var i=e.call(this)||this,a;if(Rr(r)||!r)a={next:r??void 0,error:n??void 0,complete:o??void 0};else{var s;i&&Sn.useDeprecatedNextContext?(s=Object.create(r),s.unsubscribe=function(){return i.unsubscribe()},a={next:r.next&&ad(r.next,s),error:r.error&&ad(r.error,s),complete:r.complete&&ad(r.complete,s)}):a=r}return i.destination=new DD(a),i}return t})(cd);LD={closed:!0,next:nd,error:ND,complete:nd}});function RD(e){return Rr(e?.lift)}function Xc(e){return function(t){if(RD(t))return t.lift(function(r){try{return e(r,this)}catch(n){this.error(n)}});throw new TypeError("Unable to lift unknown Observable type")}}var ud=p(()=>{Vc()});function Lx(e,t,r,n,o){return new FD(e,t,r,n,o)}var FD,Rx=p(()=>{qa();Ad();FD=(function(e){ja(t,e);function t(r,n,o,i,a,s){var c=e.call(this,r)||this;return c.onFinalize=a,c.shouldUnsubscribe=s,c._next=n?function(l){try{n(l)}catch(A){r.error(A)}}:e.prototype._next,c._error=i?function(l){try{i(l)}catch(A){r.error(A)}finally{this.unsubscribe()}}:e.prototype._error,c._complete=o?function(){try{o()}catch(l){r.error(l)}finally{this.unsubscribe()}}:e.prototype._complete,c}return t.prototype.unsubscribe=function(){var r;if(!this.shouldUnsubscribe||this.shouldUnsubscribe()){var n=this.closed;e.prototype.unsubscribe.call(this),!n&&((r=this.onFinalize)===null||r===void 0||r.call(this))}},t})(cd)});var Fx,Px=p(()=>{ed();Fx=Yc(function(e){return function(){e(this),this.name="EmptyError",this.message="no elements in sequence"}})});function fd(e,t){var r=typeof t=="object";return new Promise(function(n,o){var i=new ld({next:function(a){n(a),i.unsubscribe()},error:o,complete:function(){r?n(t.defaultValue):o(new Fx)}});e.subscribe(i)})}var Ox=p(()=>{Px();Ad()});var Gx=p(()=>{});function Ux(e,t,r,n,o){return function(i,a){var s=r,c=t,l=0;i.subscribe(Lx(a,function(A){var u=l++;c=s?e(c,A,u):(s=!0,A),n&&a.next(c)},o&&(function(){s&&a.next(c),a.complete()})))}}var Hx=p(()=>{Rx()});function jx(e,t){return Xc(Ux(e,t,arguments.length>=2,!1,!0))}var qx=p(()=>{Hx();ud()});function dd(){return Xc(function(e,t){jx(PD,[])(e).subscribe(t)})}var PD,Jx=p(()=>{qx();ud();PD=function(e,t){return e.push(t),e}});var Vx=p(()=>{Ox();Gx();Jx()});var Yx=p(()=>{});var zx=p(()=>{});function OD(){return Wx||(Wx=[IDBDatabase,IDBObjectStore,IDBIndex,IDBCursor,IDBTransaction])}function GD(){return $x||($x=[IDBCursor.prototype.advance,IDBCursor.prototype.continue,IDBCursor.prototype.continuePrimaryKey])}function UD(e){let t=new Promise((r,n)=>{let o=()=>{e.removeEventListener("success",i),e.removeEventListener("error",a)},i=()=>{r(go(e.result)),o()},a=()=>{n(e.error),o()};e.addEventListener("success",i),e.addEventListener("error",a)});return Zc.set(t,e),t}function HD(e){if(hd.has(e))return;let t=new Promise((r,n)=>{let o=()=>{e.removeEventListener("complete",i),e.removeEventListener("error",a),e.removeEventListener("abort",a)},i=()=>{r(),o()},a=()=>{n(e.error||new DOMException("AbortError","AbortError")),o()};e.addEventListener("complete",i),e.addEventListener("error",a),e.addEventListener("abort",a)});hd.set(e,t)}function ey(e){Cd=e(Cd)}function jD(e){return GD().includes(e)?function(...t){return e.apply(Ed(this),t),go(this.request)}:function(...t){return go(e.apply(Ed(this),t))}}function qD(e){return typeof e=="function"?jD(e):(e instanceof IDBTransaction&&HD(e),gd(e,OD())?new Proxy(e,Cd):e)}function go(e){if(e instanceof IDBRequest)return UD(e);if(md.has(e))return md.get(e);let t=qD(e);return t!==e&&(md.set(e,t),Zc.set(t,e)),t}function cn(e,t,{blocked:r,upgrade:n,blocking:o,terminated:i}={}){let a=indexedDB.open(e,t),s=go(a);return n&&a.addEventListener("upgradeneeded",c=>{n(go(a.result),c.oldVersion,c.newVersion,go(a.transaction),c)}),r&&a.addEventListener("blocked",c=>r(c.oldVersion,c.newVersion,c)),s.then(c=>{i&&c.addEventListener("close",()=>i()),o&&c.addEventListener("versionchange",l=>o(l.oldVersion,l.newVersion,l))}).catch(()=>{}),s}function Kx(e,t){if(!(e instanceof IDBDatabase&&!(t in e)&&typeof t=="string"))return;if(pd.get(t))return pd.get(t);let r=t.replace(/FromIndex$/,""),n=t!==r,o=VD.includes(r);if(!(r in(n?IDBIndex:IDBObjectStore).prototype)||!(o||JD.includes(r)))return;let i=async function(a,...s){let c=this.transaction(a,o?"readwrite":"readonly"),l=c.store;return n&&(l=l.index(s.shift())),(await Promise.all([l[r](...s),o&&c.done]))[0]};return pd.set(t,i),i}async function*WD(...e){let t=this;if(t instanceof IDBCursor||(t=await t.openCursor(...e)),!t)return;t=t;let r=new Proxy(t,zD);for(ty.set(r,t),Zc.set(r,Ed(t));t;)yield r,t=await(Id.get(r)||t.continue()),Id.delete(r)}function Zx(e,t){return t===Symbol.asyncIterator&&gd(e,[IDBIndex,IDBObjectStore,IDBCursor])||t==="iterate"&&gd(e,[IDBIndex,IDBObjectStore])}var gd,Wx,$x,hd,md,Zc,Cd,Ed,JD,VD,pd,YD,Xx,Id,ty,zD,_i=p(()=>{gd=(e,t)=>t.some(r=>e instanceof r);hd=new WeakMap,md=new WeakMap,Zc=new WeakMap;Cd={get(e,t,r){if(e instanceof IDBTransaction){if(t==="done")return hd.get(e);if(t==="store")return r.objectStoreNames[1]?void 0:r.objectStore(r.objectStoreNames[0])}return go(e[t])},set(e,t,r){return e[t]=r,!0},has(e,t){return e instanceof IDBTransaction&&(t==="done"||t==="store")?!0:t in e}};Ed=e=>Zc.get(e);JD=["get","getKey","getAll","getAllKeys","count"],VD=["put","add","delete","clear"],pd=new Map;ey(e=>({...e,get:(t,r,n)=>Kx(t,r)||e.get(t,r,n),has:(t,r)=>!!Kx(t,r)||e.has(t,r)}));YD=["continue","continuePrimaryKey","advance"],Xx={},Id=new WeakMap,ty=new WeakMap,zD={get(e,t){if(!YD.includes(t))return e[t];let r=Xx[t];return r||(r=Xx[t]=function(...n){Id.set(this,ty.get(this)[t](...n))}),r}};ey(e=>({...e,get(t,r,n){return Zx(t,r)?WD:e.get(t,r,n)},has(t,r){return Zx(t,r)||e.has(t,r)}}))});var ry=p(()=>{_i()});var el,ny=p(()=>{el=f(Pt(),1)});function yd(e,t=10){let r=String(e),n=0;for(let o=0,i=r.length;o<i;o++)n+=XD[r.charCodeAt(o)]??ZD;return n*t}function wd(e){let t=0;if(e.length===0)return t;for(let r=0;r<e.length;r++){let n=e.charCodeAt(r);t=(t<<5)-t+n,t|=0}return t}function eN(e){let{uri:t,baseUri:r=""}=e,n;try{n=new URL(t,r).href}catch{n=t}return n}function bd(e){return ir(e)?Hc(e)?eN(e):JSON.stringify(e):String(e)}function oy(e){let t=/(^|[\s\n]|<[A-Za-z]*\/?>)((?:https?|ftp):\/\/[-A-Z0-9+\u0026\u2019@#/%?=()~_|!:,.;]*[-A-Z0-9+\u0026@#/%=~()_|])/gi;return e.replaceAll(t,`$1<a href='$2' target="_blank">$2</a>`)}function iy(e,t){let{padding:r=30,minWidth:n=80,fontSize:o=12,maxWidth:i=1e3,stripHTML:a=!1}=t||{};return Bd(e.map(s=>bd(s)).map(s=>a?nx(s):s).map(s=>yd(s,o)).map(s=>Math.min(Math.max(s+r,n),i)))}function Bd(e,t=Number.NEGATIVE_INFINITY){let r=t;for(let n of e)r=Math.max(n,r);return r}function ir(e){return typeof e=="object"&&e!==null}var xd,Ti,$D,KD,S9,Q9,v9,M9,XD,ZD,Qn=p(()=>{xd=f(M(),1);Vf();Ti=f(Pt(),1),$D=f(ex(),1),KD=f(rx(),1);Yf();zf();zf();sx();cx();lx();Yf();hx();Cx();Ex();Ix();Yx();zx();ox();ix();ny();ry();S9=180/Math.PI,Q9=Math.PI/180,v9=/electron/i.test(typeof navigator<"u"?navigator.userAgent:""),M9=typeof jest>"u"?typeof window<"u"&&window.requestIdleCallback?window.requestIdleCallback:e=>setTimeout(()=>{e()},1):e=>{e()},XD=[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,.2796875,.2765625,.3546875,.5546875,.5546875,.8890625,.665625,.190625,.3328125,.3328125,.3890625,.5828125,.2765625,.3328125,.2765625,.3015625,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.2765625,.2765625,.584375,.5828125,.584375,.5546875,1.0140625,.665625,.665625,.721875,.721875,.665625,.609375,.7765625,.721875,.2765625,.5,.665625,.5546875,.8328125,.721875,.7765625,.665625,.7765625,.721875,.665625,.609375,.721875,.665625,.94375,.665625,.665625,.609375,.2765625,.3546875,.2765625,.4765625,.5546875,.3328125,.5546875,.5546875,.5,.5546875,.5546875,.2765625,.5546875,.5546875,.221875,.240625,.5,.221875,.8328125,.5546875,.5546875,.5546875,.5546875,.3328125,.5,.2765625,.5546875,.5,.721875,.5,.5,.5,.3546875,.259375,.353125,.5890625],ZD=.5279276315789471});function ay(e,t){(t==null||t>e.length)&&(t=e.length);for(var r=0,n=Array(t);r<t;r++)n[r]=e[r];return n}function tN(e){if(Array.isArray(e))return e}function rN(e,t){var r=e==null?null:typeof Symbol<"u"&&e[Symbol.iterator]||e["@@iterator"];if(r!=null){var n,o,i,a,s=[],c=!0,l=!1;try{if(i=(r=r.call(e)).next,t!==0)for(;!(c=(n=i.call(r)).done)&&(s.push(n.value),s.length!==t);c=!0);}catch(A){l=!0,o=A}finally{try{if(!c&&r.return!=null&&(a=r.return(),Object(a)!==a))return}finally{if(l)throw o}}return s}}function nN(){throw new TypeError(`Invalid attempt to destructure non-iterable instance.
-In order to be iterable, non-array objects must have a [Symbol.iterator]() method.`)}function oN(e,t){return tN(e)||rN(e,t)||iN(e,t)||nN()}function iN(e,t){if(e){if(typeof e=="string")return ay(e,t);var r={}.toString.call(e).slice(8,-1);return r==="Object"&&e.constructor&&(r=e.constructor.name),r==="Map"||r==="Set"?Array.from(e):r==="Arguments"||/^(?:Ui|I)nt(?:8|16|32)(?:Clamped)?Array$/.test(r)?ay(e,t):void 0}}function je(e){return function(t){t instanceof RegExp&&(t.lastIndex=0);for(var r=arguments.length,n=new Array(r>1?r-1:0),o=1;o<r;o++)n[o-1]=arguments[o];return Td(e,t,n)}}function mN(e){return function(){for(var t=arguments.length,r=new Array(t),n=0;n<t;n++)r[n]=arguments[n];return kd(e,r)}}function K(e,t){let r=arguments.length>2&&arguments[2]!==void 0?arguments[2]:Ya;if(sy&&sy(e,null),!Mn(t))return e;let n=t.length;for(;n--;){let o=t[n];if(typeof o=="string"){let i=r(o);i!==o&&(aN(t)||(t[n]=i),o=i)}e[o]=!0}return e}function pN(e){for(let t=0;t<e.length;t++)Ze(e,t)||(e[t]=null);return e}function Qt(e){let t=Ni(null);for(let n of xy(e)){var r=oN(n,2);let o=r[0],i=r[1];Ze(e,o)&&(Mn(i)?t[o]=pN(i):i&&typeof i=="object"&&i.constructor===Object?t[o]=Qt(i):t[o]=i)}return t}function gN(e){switch(typeof e){case"string":return e;case"number":return fN(e);case"boolean":return dN(e);case"bigint":return uy?uy(e):"0";case"symbol":return fy?fy(e):"Symbol()";case"undefined":return Va(e);case"function":case"object":{if(e===null)return Va(e);let t=e,r=Fr(t,"toString");if(typeof r=="function"){let n=r(t);return typeof n=="string"?n:Va(n)}return Va(e)}default:return Va(e)}}function Fr(e,t){for(;e!==null;){let n=cN(e,t);if(n){if(n.get)return je(n.get);if(typeof n.value=="function")return je(n.value)}e=sN(e)}function r(){return null}return r}function hN(e){try{return Xe(e,""),!0}catch{return!1}}function wy(){let e=arguments.length>0&&arguments[0]!==void 0?arguments[0]:TN(),t=D=>wy(D);if(t.version="3.4.12",t.removed=[],!e||!e.document||e.document.nodeType!==qt.document||!e.Element)return t.isSupported=!1,t;let r=e.document,n=r,o=n.currentScript;e.DocumentFragment;let i=e.HTMLTemplateElement,a=e.Node,s=e.Element,c=e.NodeFilter,l=e.NamedNodeMap;l===void 0&&(e.NamedNodeMap||e.MozNamedAttrMap),e.HTMLFormElement;let A=e.DOMParser,u=e.trustedTypes,m=s.prototype,d=Fr(m,"cloneNode"),g=Fr(m,"remove"),C=Fr(m,"nextSibling"),y=Fr(m,"childNodes"),I=Fr(m,"parentNode"),E=Fr(m,"shadowRoot"),b=Fr(m,"attributes"),x=a&&a.prototype?Fr(a.prototype,"nodeType"):null,w=a&&a.prototype?Fr(a.prototype,"nodeName"):null;if(typeof i=="function"){let D=r.createElement("template");D.content&&D.content.ownerDocument&&(r=D.content.ownerDocument)}let Q,S="",k,N=!1,_=0,v=function(){if(_>0)throw ho('A configured TRUSTED_TYPES_POLICY callback (createHTML or createScriptURL) must not call DOMPurify.sanitize, as that causes infinite recursion. Do not pass a policy whose callbacks wrap DOMPurify as TRUSTED_TYPES_POLICY; see the "DOMPurify and Trusted Types" section of the README.')},L=function(h){v(),_++;try{return Q.createHTML(h)}finally{_--}},U=function(h){v(),_++;try{return Q.createScriptURL(h)}finally{_--}},W=function(){return N||(k=kN(u,o),N=!0),k},se=r,Te=se.implementation,Oe=se.createNodeIterator,pn=se.createDocumentFragment,Kn=se.getElementsByTagName,It=n.importNode,Ae=Iy();t.isSupported=typeof xy=="function"&&typeof I=="function"&&Te&&Te.createHTMLDocument!==void 0;let gn=IN,$r=xN,No=yN,ra=wN,Lo=bN,Kr=BN,hn=SN,NA=vN,na=hy,ge=null,ws=K({},[...dy,...Qd,...vd,...Md,...my]),we=null,Cn=K({},[...py,..._d,...gy,...tl]),he=Object.seal(Ni(null,{tagNameCheck:{writable:!0,configurable:!1,enumerable:!0,value:null},attributeNameCheck:{writable:!0,configurable:!1,enumerable:!0,value:null},allowCustomizedBuiltInElements:{writable:!0,configurable:!1,enumerable:!0,value:!1}})),Ro=null,ne=null,te=Object.seal(Ni(null,{tagCheck:{writable:!0,configurable:!1,enumerable:!0,value:null},attributeCheck:{writable:!0,configurable:!1,enumerable:!0,value:null}})),be=!0,Ce=!0,Rt=!1,xt=!0,ce=!1,Ge=!0,Ft=!1,Xr=!1,Fo=null,Po=null,At=!1,ut=!1,En=!1,Oo=!1,Go=!0,Yp=!1,zp="user-content-",LA=!0,RA=!1,Uo={},Mr=null,FA=K({},["annotation-xml","audio","colgroup","desc","foreignobject","head","iframe","math","mi","mn","mo","ms","mtext","noembed","noframes","noscript","plaintext","script","selectedcontent","style","svg","template","thead","title","video","xmp"]),Wp=null,$p=K({},["audio","video","img","source","image","track"]),PA=null,Kp=K({},["alt","class","for","id","label","name","pattern","placeholder","role","summary","title","value","style","xmlns"]),bs="http://www.w3.org/1998/Math/MathML",Bs="http://www.w3.org/2000/svg",_r="http://www.w3.org/1999/xhtml",Ho=_r,OA=!1,GA=null,ZM=K({},[bs,Bs,_r],Sd),Xp=at(["mi","mo","mn","ms","mtext"]),UA=K({},Xp),Zp=at(["annotation-xml"]),HA=K({},Zp),e_=K({},["title","style","font","a","script"]),oa=null,t_=["application/xhtml+xml","text/html"],r_="text/html",Qe=null,jo=null,n_=r.createElement("form"),eg=function(h){return h instanceof RegExp||h instanceof Function},jA=function(){let h=arguments.length>0&&arguments[0]!==void 0?arguments[0]:{};if(jo&&jo===h)return;(!h||typeof h!="object")&&(h={}),h=Qt(h),oa=t_.indexOf(h.PARSER_MEDIA_TYPE)===-1?r_:h.PARSER_MEDIA_TYPE,Qe=oa==="application/xhtml+xml"?Sd:Ya,ge=vn(h,"ALLOWED_TAGS",ws,{transform:Qe}),we=vn(h,"ALLOWED_ATTR",Cn,{transform:Qe}),GA=vn(h,"ALLOWED_NAMESPACES",ZM,{transform:Sd}),PA=vn(h,"ADD_URI_SAFE_ATTR",Kp,{transform:Qe,base:Kp}),Wp=vn(h,"ADD_DATA_URI_TAGS",$p,{transform:Qe,base:$p}),Mr=vn(h,"FORBID_CONTENTS",FA,{transform:Qe}),Ro=vn(h,"FORBID_TAGS",Qt({}),{transform:Qe}),ne=vn(h,"FORBID_ATTR",Qt({}),{transform:Qe}),Uo=Ze(h,"USE_PROFILES")?h.USE_PROFILES&&typeof h.USE_PROFILES=="object"?Qt(h.USE_PROFILES):h.USE_PROFILES:!1,be=h.ALLOW_ARIA_ATTR!==!1,Ce=h.ALLOW_DATA_ATTR!==!1,Rt=h.ALLOW_UNKNOWN_PROTOCOLS||!1,xt=h.ALLOW_SELF_CLOSE_IN_ATTR!==!1,ce=h.SAFE_FOR_TEMPLATES||!1,Ge=h.SAFE_FOR_XML!==!1,Ft=h.WHOLE_DOCUMENT||!1,ut=h.RETURN_DOM||!1,En=h.RETURN_DOM_FRAGMENT||!1,Oo=h.RETURN_TRUSTED_TYPE||!1,At=h.FORCE_BODY||!1,Go=h.SANITIZE_DOM!==!1,Yp=h.SANITIZE_NAMED_PROPS||!1,LA=h.KEEP_CONTENT!==!1,RA=h.IN_PLACE||!1,na=hN(h.ALLOWED_URI_REGEXP)?h.ALLOWED_URI_REGEXP:hy,Ho=typeof h.NAMESPACE=="string"?h.NAMESPACE:_r,UA=Ze(h,"MATHML_TEXT_INTEGRATION_POINTS")&&h.MATHML_TEXT_INTEGRATION_POINTS&&typeof h.MATHML_TEXT_INTEGRATION_POINTS=="object"?Qt(h.MATHML_TEXT_INTEGRATION_POINTS):K({},Xp),HA=Ze(h,"HTML_INTEGRATION_POINTS")&&h.HTML_INTEGRATION_POINTS&&typeof h.HTML_INTEGRATION_POINTS=="object"?Qt(h.HTML_INTEGRATION_POINTS):K({},Zp);let B=Ze(h,"CUSTOM_ELEMENT_HANDLING")&&h.CUSTOM_ELEMENT_HANDLING&&typeof h.CUSTOM_ELEMENT_HANDLING=="object"?Qt(h.CUSTOM_ELEMENT_HANDLING):Ni(null);if(he=Ni(null),Ze(B,"tagNameCheck")&&eg(B.tagNameCheck)&&(he.tagNameCheck=B.tagNameCheck),Ze(B,"attributeNameCheck")&&eg(B.attributeNameCheck)&&(he.attributeNameCheck=B.attributeNameCheck),Ze(B,"allowCustomizedBuiltInElements")&&typeof B.allowCustomizedBuiltInElements=="boolean"&&(he.allowCustomizedBuiltInElements=B.allowCustomizedBuiltInElements),st(he),ce&&(Ce=!1),En&&(ut=!0),Uo&&(ge=K({},my),we=Ni(null),Uo.html===!0&&(K(ge,dy),K(we,py)),Uo.svg===!0&&(K(ge,Qd),K(we,_d),K(we,tl)),Uo.svgFilters===!0&&(K(ge,vd),K(we,_d),K(we,tl)),Uo.mathMl===!0&&(K(ge,Md),K(we,gy),K(we,tl))),te.tagCheck=null,te.attributeCheck=null,Ze(h,"ADD_TAGS")&&(typeof h.ADD_TAGS=="function"?te.tagCheck=h.ADD_TAGS:Mn(h.ADD_TAGS)&&(ge===ws&&(ge=Qt(ge)),K(ge,h.ADD_TAGS,Qe))),Ze(h,"ADD_ATTR")&&(typeof h.ADD_ATTR=="function"?te.attributeCheck=h.ADD_ATTR:Mn(h.ADD_ATTR)&&(we===Cn&&(we=Qt(we)),K(we,h.ADD_ATTR,Qe))),Ze(h,"ADD_URI_SAFE_ATTR")&&Mn(h.ADD_URI_SAFE_ATTR)&&K(PA,h.ADD_URI_SAFE_ATTR,Qe),Ze(h,"FORBID_CONTENTS")&&Mn(h.FORBID_CONTENTS)&&(Mr===FA&&(Mr=Qt(Mr)),K(Mr,h.FORBID_CONTENTS,Qe)),Ze(h,"ADD_FORBID_CONTENTS")&&Mn(h.ADD_FORBID_CONTENTS)&&(Mr===FA&&(Mr=Qt(Mr)),K(Mr,h.ADD_FORBID_CONTENTS,Qe)),LA&&(ge["#text"]=!0),Ft&&K(ge,["html","head","body"]),ge.table&&(K(ge,["tbody"]),delete Ro.tbody),h.TRUSTED_TYPES_POLICY){if(typeof h.TRUSTED_TYPES_POLICY.createHTML!="function")throw ho('TRUSTED_TYPES_POLICY configuration option must provide a "createHTML" hook.');if(typeof h.TRUSTED_TYPES_POLICY.createScriptURL!="function")throw ho('TRUSTED_TYPES_POLICY configuration option must provide a "createScriptURL" hook.');let T=Q;Q=h.TRUSTED_TYPES_POLICY;try{S=L("")}catch(P){throw Q=T,P}}else h.TRUSTED_TYPES_POLICY===null?(Q=void 0,S=""):(Q===void 0&&(Q=W()),Q&&typeof S=="string"&&(S=L("")));at&&at(h),jo=h},tg=K({},[...Qd,...vd,...CN]),rg=K({},[...Md,...EN]),o_=function(h,B,T){return B.namespaceURI===_r?h==="svg":B.namespaceURI===bs?h==="svg"&&(T==="annotation-xml"||UA[T]):!!tg[h]},i_=function(h,B,T){return B.namespaceURI===_r?h==="math":B.namespaceURI===Bs?h==="math"&&HA[T]:!!rg[h]},a_=function(h,B,T){return B.namespaceURI===Bs&&!HA[T]||B.namespaceURI===bs&&!UA[T]?!1:!rg[h]&&(e_[h]||!tg[h])},s_=function(h){let B=I(h);(!B||!B.tagName)&&(B={namespaceURI:Ho,tagName:"template"});let T=Ya(h.tagName),P=Ya(B.tagName);return GA[h.namespaceURI]?h.namespaceURI===Bs?o_(T,B,P):h.namespaceURI===bs?i_(T,B,P):h.namespaceURI===_r?a_(T,B,P):!!(oa==="application/xhtml+xml"&&GA[h.namespaceURI]):!1},In=function(h){Di(t.removed,{element:h});try{I(h).removeChild(h)}catch{if(g(h),!I(h))throw ho("a node selected for removal could not be detached from its tree and cannot be safely returned; refusing to sanitize in place")}},Ss=function(h){qA(h);let B=y(h);if(B){let P=[];ki(B,q=>{Di(P,q)}),ki(P,q=>{try{g(q)}catch{}})}let T=b(h);if(T)for(let P=T.length-1;P>=0;--P){let q=T[P],J=q&&q.name;if(typeof J=="string")try{h.removeAttribute(J)}catch{}}},Xn=function(h,B){try{Di(t.removed,{attribute:B.getAttributeNode(h),from:B})}catch{Di(t.removed,{attribute:null,from:B})}if(B.removeAttribute(h),h==="is")if(ut||En)try{In(B)}catch{}else try{B.setAttribute(h,"")}catch{}},c_=function(h){let B=b(h);if(B)for(let T=B.length-1;T>=0;--T){let P=B[T],q=P&&P.name;if(!(typeof q!="string"||we[Qe(q)]))try{h.removeAttribute(q)}catch{}}},qA=function(h){let B=[h];for(;B.length>0;){let T=B.pop();(x?x(T):T.nodeType)===qt.element&&c_(T);let q=y(T);if(q)for(let J=q.length-1;J>=0;--J)B.push(q[J])}},l_=function(h){if(!Ge)return;let B=[h];for(;B.length>0;){let T=B.pop(),P=x?x(T):T.nodeType;if(P===qt.processingInstruction||P===qt.comment&&Xe(Ey,T.data)){try{g(T)}catch{}continue}if(P===qt.element){let J=T,ke=Qe(w?w(T):T.nodeName);try{J.hasAttribute&&J.hasAttribute("patchsrc")&&J.removeAttribute("patchsrc"),J.hasAttribute&&J.hasAttribute("for")&&ke!=="label"&&ke!=="output"&&J.removeAttribute("for")}catch{}}let q=y(T);if(q)for(let J=q.length-1;J>=0;--J)B.push(q[J])}},ng=function(h){let B=null,T=null;if(At)h="<remove></remove>"+h;else{let J=ly(h,/^[\r\n\t ]+/);T=J&&J[0]}oa==="application/xhtml+xml"&&Ho===_r&&(h='<html xmlns="http://www.w3.org/1999/xhtml"><head></head><body>'+h+"</body></html>");let P=Q?L(h):h;if(Ho===_r)try{B=new A().parseFromString(P,oa)}catch{}if(!B||!B.documentElement){B=Te.createDocument(Ho,"template",null);try{B.documentElement.innerHTML=OA?S:P}catch{}}let q=B.body||B.documentElement;return h&&T&&q.insertBefore(r.createTextNode(T),q.childNodes[0]||null),Ho===_r?Kn.call(B,Ft?"html":"body")[0]:Ft?B.documentElement:q},og=function(h){return Oe.call(h.ownerDocument||h,h,c.SHOW_ELEMENT|c.SHOW_COMMENT|c.SHOW_TEXT|c.SHOW_PROCESSING_INSTRUCTION|c.SHOW_CDATA_SECTION,null)},Qs=function(h){return h=Ja(h,gn," "),h=Ja(h,$r," "),h=Ja(h,No," "),h},JA=function(h){var B;h.normalize();let T=Oe.call(h.ownerDocument||h,h,c.SHOW_TEXT|c.SHOW_COMMENT|c.SHOW_CDATA_SECTION|c.SHOW_PROCESSING_INSTRUCTION,null),P=T.nextNode();for(;P;)P.data=Qs(P.data),P=T.nextNode();let q=(B=h.querySelectorAll)===null||B===void 0?void 0:B.call(h,"template");q&&ki(q,J=>{qo(J.content)&&JA(J.content)})},vs=function(h){let B=w?w(h):null;return typeof B!="string"||Qe(B)!=="form"?!1:typeof h.nodeName!="string"||typeof h.textContent!="string"||typeof h.removeChild!="function"||h.attributes!==b(h)||typeof h.removeAttribute!="function"||typeof h.setAttribute!="function"||typeof h.namespaceURI!="string"||typeof h.insertBefore!="function"||typeof h.hasChildNodes!="function"||h.nodeType!==x(h)||h.childNodes!==y(h)},qo=function(h){if(!x||typeof h!="object"||h===null)return!1;try{return x(h)===qt.documentFragment}catch{return!1}},ia=function(h){if(!x||typeof h!="object"||h===null)return!1;try{return typeof x(h)=="number"}catch{return!1}};function Tr(D,h,B){D.length!==0&&ki(D,T=>{T.call(t,h,B,jo)})}let A_=function(h,B){return!!(Ge&&h.hasChildNodes()&&!ia(h.firstElementChild)&&Xe(Cy,h.textContent)&&Xe(Cy,h.innerHTML)||Ge&&h.namespaceURI===_r&&B==="style"&&ia(h.firstElementChild)||h.nodeType===qt.processingInstruction||Ge&&h.nodeType===qt.comment&&Xe(Ey,h.data))},u_=function(h,B){if(!Ro[B]&&sg(B)&&(he.tagNameCheck instanceof RegExp&&Xe(he.tagNameCheck,B)||he.tagNameCheck instanceof Function&&he.tagNameCheck(B)))return!1;if(LA&&!Mr[B]){let T=I(h),P=y(h);if(P&&T){let q=P.length;for(let J=q-1;J>=0;--J){let ke=RA?P[J]:d(P[J],!0);T.insertBefore(ke,C(h))}}}return In(h),!0},ig=function(h,B){if(Tr(Ae.beforeSanitizeElements,h,null),h!==B&&I(h)===null)return!0;if(vs(h))return In(h),!0;let T=Qe(w?w(h):h.nodeName);if(Tr(Ae.uponSanitizeElement,h,{tagName:T,allowedTags:ge}),h!==B&&I(h)===null)return!0;if(A_(h,T))return In(h),!0;if(Ro[T]||!(te.tagCheck instanceof Function&&te.tagCheck(T))&&!ge[T]){let q=u_(h,T);return q===!1&&Tr(Ae.afterSanitizeElements,h,null),q}if((x?x(h):h.nodeType)===qt.element&&!s_(h)||(T==="noscript"||T==="noembed"||T==="noframes")&&Xe(MN,h.innerHTML))return In(h),!0;if(ce&&h.nodeType===qt.text){let q=Qs(h.textContent);h.textContent!==q&&(Di(t.removed,{element:h.cloneNode()}),h.textContent=q)}return Tr(Ae.afterSanitizeElements,h,null),!1},ag=function(h,B,T){if(ne[B]||Ge&&B==="patchsrc"||Ge&&B==="for"&&h!=="label"&&h!=="output"||Go&&(B==="id"||B==="name")&&(T in r||T in n_))return!1;let P=we[B]||te.attributeCheck instanceof Function&&te.attributeCheck(B,h);if(!(Ce&&Xe(ra,B))){if(!(be&&Xe(Lo,B))){if(P){if(!PA[B]){if(!Xe(na,Ja(T,hn,""))){if(!((B==="src"||B==="xlink:href"||B==="href")&&h!=="script"&&Ay(T,"data:")===0&&Wp[h])){if(!(Rt&&!Xe(Kr,Ja(T,hn,"")))){if(T)return!1}}}}}else if(!(sg(h)&&(he.tagNameCheck instanceof RegExp&&Xe(he.tagNameCheck,h)||he.tagNameCheck instanceof Function&&he.tagNameCheck(h))&&(he.attributeNameCheck instanceof RegExp&&Xe(he.attributeNameCheck,B)||he.attributeNameCheck instanceof Function&&he.attributeNameCheck(B,h))||B==="is"&&he.allowCustomizedBuiltInElements&&(he.tagNameCheck instanceof RegExp&&Xe(he.tagNameCheck,T)||he.tagNameCheck instanceof Function&&he.tagNameCheck(T))))return!1}}return!0},f_=K({},["annotation-xml","color-profile","font-face","font-face-format","font-face-name","font-face-src","font-face-uri","missing-glyph"]),sg=function(h){return!f_[Ya(h)]&&Xe(NA,h)},d_=function(h,B,T,P){if(Q&&typeof u=="object"&&typeof u.getAttributeType=="function"&&!T)switch(u.getAttributeType(h,B)){case"TrustedHTML":return L(P);case"TrustedScriptURL":return U(P)}return P},m_=function(h,B,T,P){try{T?h.setAttributeNS(T,B,P):h.setAttribute(B,P),vs(h)?In(h):cy(t.removed)}catch{Xn(B,h)}},cg=function(h){Tr(Ae.beforeSanitizeAttributes,h,null);let B=h.attributes;if(!B||vs(h))return;let T={attrName:"",attrValue:"",keepAttr:!0,allowedAttributes:we,forceKeepAttr:void 0},P=B.length,q=Qe(h.nodeName);for(;P--;){let J=B[P],ke=J.name,ft=J.namespaceURI,fr=J.value,kt=Qe(ke),dr=fr,yt=ke==="value"?dr:uN(dr);if(T.attrName=kt,T.attrValue=yt,T.keepAttr=!0,T.forceKeepAttr=void 0,Tr(Ae.uponSanitizeAttribute,h,T),yt=T.attrValue,Yp&&(kt==="id"||kt==="name")&&Ay(yt,zp)!==0&&(Xn(ke,h),yt=zp+yt),Ge&&Xe(/((--!?|])>)|<\/(style|script|title|xmp|textarea|noscript|iframe|noembed|noframes)/i,yt)){Xn(ke,h);continue}if(kt==="attributename"&&ly(yt,"href")){Xn(ke,h);continue}if(!T.forceKeepAttr){if(!T.keepAttr){Xn(ke,h);continue}if(!xt&&Xe(_N,yt)){Xn(ke,h);continue}if(ce&&(yt=Qs(yt)),!ag(q,kt,yt)){Xn(ke,h);continue}yt=d_(q,kt,ft,yt),yt!==dr&&m_(h,ke,ft,yt)}}Tr(Ae.afterSanitizeAttributes,h,null)},Ms=function(h){let B=null,T=og(h);for(Tr(Ae.beforeSanitizeShadowDOM,h,null);B=T.nextNode();)if(Tr(Ae.uponSanitizeShadowNode,B,null),ig(B,h),cg(B),qo(B.content)&&Ms(B.content),(x?x(B):B.nodeType)===qt.element){let q=E(B);qo(q)&&(VA(q),Ms(q))}Tr(Ae.afterSanitizeShadowDOM,h,null)},VA=function(h){let B=[{node:h,shadow:null}];for(;B.length>0;){let T=B.pop();if(T.shadow){Ms(T.shadow);continue}let P=T.node,J=(x?x(P):P.nodeType)===qt.element,ke=y(P);if(ke)for(let ft=ke.length-1;ft>=0;--ft)B.push({node:ke[ft],shadow:null});if(J){let ft=w?w(P):null;if(typeof ft=="string"&&Qe(ft)==="template"){let fr=P.content;qo(fr)&&B.push({node:fr,shadow:null})}}if(J){let ft=E(P);qo(ft)&&B.push({node:null,shadow:ft},{node:ft,shadow:null})}}};return t.sanitize=function(D){let h=arguments.length>1&&arguments[1]!==void 0?arguments[1]:{},B=null,T=null,P=null,q=null;if(OA=!D,OA&&(D="<!-->"),typeof D!="string"&&!ia(D)&&(D=gN(D),typeof D!="string"))throw ho("dirty is not a string, aborting");if(!t.isSupported)return D;Xr?(ge=Fo,we=Po):jA(h),(Ae.uponSanitizeElement.length>0||Ae.uponSanitizeAttribute.length>0)&&(ge=Qt(ge)),Ae.uponSanitizeAttribute.length>0&&(we=Qt(we)),t.removed=[];let J=RA&&typeof D!="string"&&ia(D);if(J){l_(D);let kt=w?w(D):D.nodeName;if(typeof kt=="string"){let dr=Qe(kt);if(!ge[dr]||Ro[dr])throw Ss(D),ho("root node is forbidden and cannot be sanitized in-place")}if(vs(D))throw Ss(D),ho("root node is clobbered and cannot be sanitized in-place");try{VA(D)}catch(dr){throw Ss(D),dr}}else if(ia(D))B=ng("<!---->"),T=B.ownerDocument.importNode(D,!0),T.nodeType===qt.element&&T.nodeName==="BODY"||T.nodeName==="HTML"?B=T:B.appendChild(T),VA(T);else{if(!ut&&!ce&&!Ft&&D.indexOf("<")===-1)return Q&&Oo?L(D):D;if(B=ng(D),!B)return ut?null:Oo?S:""}B&&At&&In(B.firstChild);let ke=J?D:B,ft=og(ke);try{for(;P=ft.nextNode();)ig(P,ke),cg(P),qo(P.content)&&Ms(P.content)}catch(kt){throw J&&(Ss(D),ki(t.removed,dr=>{dr.element&&qA(dr.element)})),kt}if(J)return ki(t.removed,kt=>{kt.element&&qA(kt.element)}),ce&&JA(D),D;if(ut){if(ce&&JA(B),En)for(q=pn.call(B.ownerDocument);B.firstChild;)q.appendChild(B.firstChild);else q=B;return(we.shadowroot||we.shadowrootmode)&&(q=It.call(n,q,!0)),q}let fr=Ft?B.outerHTML:B.innerHTML;return Ft&&ge["!doctype"]&&B.ownerDocument&&B.ownerDocument.doctype&&B.ownerDocument.doctype.name&&Xe(QN,B.ownerDocument.doctype.name)&&(fr="<!DOCTYPE "+B.ownerDocument.doctype.name+`>
-`+fr),ce&&(fr=Qs(fr)),Q&&Oo?L(fr):fr},t.setConfig=function(){let D=arguments.length>0&&arguments[0]!==void 0?arguments[0]:{};jA(D),Xr=!0,Fo=ge,Po=we},t.clearConfig=function(){jo=null,Xr=!1,Fo=null,Po=null,Q=k,S=""},t.isValidAttribute=function(D,h,B){jo||jA({});let T=Qe(D),P=Qe(h);return ag(T,P,B)},t.addHook=function(D,h){typeof h=="function"&&Ze(Ae,D)&&Di(Ae[D],h)},t.removeHook=function(D,h){if(Ze(Ae,D)){if(h!==void 0){let B=lN(Ae[D],h);return B===-1?void 0:AN(Ae[D],B,1)[0]}return cy(Ae[D])}},t.removeHooks=function(D){Ze(Ae,D)&&(Ae[D]=[])},t.removeAllHooks=function(){Ae=Iy()},t}var xy,sy,aN,sN,cN,at,st,Ni,yy,Td,kd,ki,lN,cy,Di,AN,Mn,Ya,Sd,ly,Ja,Ay,uN,fN,dN,uy,fy,Ze,Va,Xe,ho,dy,Qd,vd,CN,Md,EN,my,py,_d,gy,tl,IN,xN,yN,wN,bN,hy,BN,SN,QN,vN,Cy,Ey,MN,_N,qt,TN,kN,Iy,vn,by,By=p(()=>{xy=Object.entries,sy=Object.setPrototypeOf,aN=Object.isFrozen,sN=Object.getPrototypeOf,cN=Object.getOwnPropertyDescriptor,at=Object.freeze,st=Object.seal,Ni=Object.create,yy=typeof Reflect<"u"&&Reflect,Td=yy.apply,kd=yy.construct;at||(at=function(t){return t});st||(st=function(t){return t});Td||(Td=function(t,r){for(var n=arguments.length,o=new Array(n>2?n-2:0),i=2;i<n;i++)o[i-2]=arguments[i];return t.apply(r,o)});kd||(kd=function(t){for(var r=arguments.length,n=new Array(r>1?r-1:0),o=1;o<r;o++)n[o-1]=arguments[o];return new t(...n)});ki=je(Array.prototype.forEach),lN=je(Array.prototype.lastIndexOf),cy=je(Array.prototype.pop),Di=je(Array.prototype.push),AN=je(Array.prototype.splice),Mn=Array.isArray,Ya=je(String.prototype.toLowerCase),Sd=je(String.prototype.toString),ly=je(String.prototype.match),Ja=je(String.prototype.replace),Ay=je(String.prototype.indexOf),uN=je(String.prototype.trim),fN=je(Number.prototype.toString),dN=je(Boolean.prototype.toString),uy=typeof BigInt>"u"?null:je(BigInt.prototype.toString),fy=typeof Symbol>"u"?null:je(Symbol.prototype.toString),Ze=je(Object.prototype.hasOwnProperty),Va=je(Object.prototype.toString),Xe=je(RegExp.prototype.test),ho=mN(TypeError);dy=at(["a","abbr","acronym","address","area","article","aside","audio","b","bdi","bdo","big","blink","blockquote","body","br","button","canvas","caption","center","cite","code","col","colgroup","content","data","datalist","dd","decorator","del","details","dfn","dialog","dir","div","dl","dt","element","em","fieldset","figcaption","figure","font","footer","form","h1","h2","h3","h4","h5","h6","head","header","hgroup","hr","html","i","img","input","ins","kbd","label","legend","li","main","map","mark","marquee","menu","menuitem","meter","nav","nobr","ol","optgroup","option","output","p","picture","pre","progress","q","rp","rt","ruby","s","samp","search","section","select","shadow","slot","small","source","spacer","span","strike","strong","style","sub","summary","sup","table","tbody","td","template","textarea","tfoot","th","thead","time","tr","track","tt","u","ul","var","video","wbr"]),Qd=at(["svg","a","altglyph","altglyphdef","altglyphitem","animatecolor","animatemotion","animatetransform","circle","clippath","defs","desc","ellipse","enterkeyhint","exportparts","filter","font","g","glyph","glyphref","hkern","image","inputmode","line","lineargradient","marker","mask","metadata","mpath","part","path","pattern","polygon","polyline","radialgradient","rect","stop","style","switch","symbol","text","textpath","title","tref","tspan","view","vkern"]),vd=at(["feBlend","feColorMatrix","feComponentTransfer","feComposite","feConvolveMatrix","feDiffuseLighting","feDisplacementMap","feDistantLight","feDropShadow","feFlood","feFuncA","feFuncB","feFuncG","feFuncR","feGaussianBlur","feImage","feMerge","feMergeNode","feMorphology","feOffset","fePointLight","feSpecularLighting","feSpotLight","feTile","feTurbulence"]),CN=at(["animate","color-profile","cursor","discard","font-face","font-face-format","font-face-name","font-face-src","font-face-uri","foreignobject","hatch","hatchpath","mesh","meshgradient","meshpatch","meshrow","missing-glyph","script","set","solidcolor","unknown","use"]),Md=at(["math","menclose","merror","mfenced","mfrac","mglyph","mi","mlabeledtr","mmultiscripts","mn","mo","mover","mpadded","mphantom","mroot","mrow","ms","mspace","msqrt","mstyle","msub","msup","msubsup","mtable","mtd","mtext","mtr","munder","munderover","mprescripts"]),EN=at(["maction","maligngroup","malignmark","mlongdiv","mscarries","mscarry","msgroup","mstack","msline","msrow","semantics","annotation","annotation-xml","mprescripts","none"]),my=at(["#text"]),py=at(["accept","action","align","alt","autocapitalize","autocomplete","autopictureinpicture","autoplay","background","bgcolor","border","capture","cellpadding","cellspacing","checked","cite","class","clear","color","cols","colspan","command","commandfor","controls","controlslist","coords","crossorigin","datetime","decoding","default","dir","disabled","disablepictureinpicture","disableremoteplayback","download","draggable","enctype","enterkeyhint","exportparts","face","for","headers","height","hidden","high","href","hreflang","id","inert","inputmode","integrity","ismap","kind","label","lang","list","loading","loop","low","max","maxlength","media","method","min","minlength","multiple","muted","name","nonce","noshade","novalidate","nowrap","open","optimum","part","pattern","placeholder","playsinline","popover","popovertarget","popovertargetaction","poster","preload","pubdate","radiogroup","readonly","rel","required","rev","reversed","role","rows","rowspan","spellcheck","scope","selected","shape","size","sizes","slot","span","srclang","start","src","srcset","step","style","summary","tabindex","title","translate","type","usemap","valign","value","width","wrap","xmlns"]),_d=at(["accent-height","accumulate","additive","alignment-baseline","amplitude","ascent","attributename","attributetype","azimuth","basefrequency","baseline-shift","begin","bias","by","class","clip","clippathunits","clip-path","clip-rule","color","color-interpolation","color-interpolation-filters","color-profile","color-rendering","cx","cy","d","dx","dy","diffuseconstant","direction","display","divisor","dominant-baseline","dur","edgemode","elevation","end","exponent","fill","fill-opacity","fill-rule","filter","filterunits","flood-color","flood-opacity","font-family","font-size","font-size-adjust","font-stretch","font-style","font-variant","font-weight","fx","fy","g1","g2","glyph-name","glyphref","gradientunits","gradienttransform","height","href","id","image-rendering","in","in2","intercept","k","k1","k2","k3","k4","kerning","keypoints","keysplines","keytimes","lang","lengthadjust","letter-spacing","kernelmatrix","kernelunitlength","lighting-color","local","marker-end","marker-mid","marker-start","markerheight","markerunits","markerwidth","maskcontentunits","maskunits","max","mask","mask-type","media","method","mode","min","name","numoctaves","offset","operator","opacity","order","orient","orientation","origin","overflow","paint-order","path","pathlength","patterncontentunits","patterntransform","patternunits","points","preservealpha","preserveaspectratio","primitiveunits","r","rx","ry","radius","refx","refy","repeatcount","repeatdur","restart","result","rotate","scale","seed","shape-rendering","slope","specularconstant","specularexponent","spreadmethod","startoffset","stddeviation","stitchtiles","stop-color","stop-opacity","stroke-dasharray","stroke-dashoffset","stroke-linecap","stroke-linejoin","stroke-miterlimit","stroke-opacity","stroke","stroke-width","style","surfacescale","systemlanguage","tabindex","tablevalues","targetx","targety","transform","transform-origin","text-anchor","text-decoration","text-orientation","text-rendering","textlength","type","u1","u2","unicode","values","viewbox","visibility","version","vert-adv-y","vert-origin-x","vert-origin-y","width","word-spacing","wrap","writing-mode","xchannelselector","ychannelselector","x","x1","x2","xmlns","y","y1","y2","z","zoomandpan"]),gy=at(["accent","accentunder","align","bevelled","close","columnalign","columnlines","columnspacing","columnspan","denomalign","depth","dir","display","displaystyle","encoding","fence","frame","height","href","id","largeop","length","linethickness","lquote","lspace","mathbackground","mathcolor","mathsize","mathvariant","maxsize","minsize","movablelimits","notation","numalign","open","rowalign","rowlines","rowspacing","rowspan","rspace","rquote","scriptlevel","scriptminsize","scriptsizemultiplier","selection","separator","separators","stretchy","subscriptshift","supscriptshift","symmetric","voffset","width","xmlns"]),tl=at(["xlink:href","xml:id","xlink:title","xml:space","xmlns:xlink"]),IN=st(/{{[\w\W]*|^[\w\W]*}}/g),xN=st(/<%[\w\W]*|^[\w\W]*%>/g),yN=st(/\${[\w\W]*/g),wN=st(/^data-[\-\w.\u00B7-\uFFFF]+$/),bN=st(/^aria-[\-\w]+$/),hy=st(/^(?:(?:(?:f|ht)tps?|mailto|tel|callto|sms|cid|xmpp|matrix):|[^a-z]|[a-z+.\-]+(?:[^a-z+.\-:]|$))/i),BN=st(/^(?:\w+script|data):/i),SN=st(/[\u0000-\u0020\u00A0\u1680\u180E\u2000-\u2029\u205F\u3000]/g),QN=st(/^html$/i),vN=st(/^[a-z][.\w]*(-[.\w]+)+$/i),Cy=st(/<[/\w!]/g),Ey=st(/<[/\w]/g),MN=st(/<\/no(script|embed|frames)/i),_N=st(/\/>/i),qt={element:1,attribute:2,text:3,cdataSection:4,entityReference:5,entityNode:6,processingInstruction:7,comment:8,document:9,documentType:10,documentFragment:11,notation:12},TN=function(){return typeof window>"u"?null:window},kN=function(t,r){if(typeof t!="object"||typeof t.createPolicy!="function")return null;let n=null,o="data-tt-policy-suffix";r&&r.hasAttribute(o)&&(n=r.getAttribute(o));let i="dompurify"+(n?"#"+n:"");try{return t.createPolicy(i,{createHTML(a){return a},createScriptURL(a){return a}})}catch{return console.warn("TrustedTypes policy "+i+" could not be created."),null}},Iy=function(){return{afterSanitizeAttributes:[],afterSanitizeElements:[],afterSanitizeShadowDOM:[],beforeSanitizeAttributes:[],beforeSanitizeElements:[],beforeSanitizeShadowDOM:[],uponSanitizeAttribute:[],uponSanitizeElement:[],uponSanitizeShadowNode:[]}},vn=function(t,r,n,o){return Ze(t,r)&&Mn(t[r])?K(o.base?Qt(o.base):{},t[r],o.transform):n};by=wy()});var vy={};dt(vy,{default:()=>Qy});function Qy({value:e,className:t}){let r=(0,rl.useRef)(null);return(0,rl.useLayoutEffect)(()=>{let n=r.current;if(n)for(let o of n.querySelectorAll("a"))o.setAttribute("rel","noopener noreferrer"),o.setAttribute("target","_blank")},[e]),(0,Sy.jsx)("span",{ref:r,className:t,dangerouslySetInnerHTML:{__html:by.sanitize(e)}})}var Sy,rl,My=p(()=>{Sy=f(R(),1),rl=f(M(),1);By()});function RN(e){return LN.test(e)}function FN(e){return e.includes("<")||e.includes("://")}function PN({value:e,className:t}){let r=(0,_n.useRef)(null);return(0,_n.useLayoutEffect)(()=>{let n=r.current;if(n)try{n.setHTML(e);for(let o of n.querySelectorAll("a"))o.setAttribute("rel","noopener noreferrer"),o.setAttribute("target","_blank")}catch(o){console.error(o)}},[e]),(0,Co.jsx)("span",{ref:r,className:t})}function Tn({html:e,className:t}){let r=`${e}`;if(!FN(r))return(0,Co.jsx)("span",{className:t,children:r});let n=oy(r),o=RN(n)?n:(0,_y.default)(n);return typeof Element<"u"&&Element.prototype.setHTML?(0,Co.jsx)(PN,{value:o,className:t}):(0,Co.jsx)(_n.Suspense,{fallback:(0,Co.jsx)("span",{className:t}),children:(0,Co.jsx)(NN,{value:o,className:t})})}var Co,_n,_y,DN,NN,LN,Dd=p(()=>{Co=f(R(),1),_n=f(M(),1),_y=f(_E(),1);Qn();DN=["a","b","br","code","div","em","h1","h2","h3","h4","h5","h6","i","img","li","mark","p","pre","span","small","strong","table","tbody","sup","sub","td","tfoot","th","thead","tr","u","ul"],NN=(0,_n.lazy)(()=>Promise.resolve().then(()=>(My(),vy))),LN=new RegExp(DN.map(e=>String.raw`<${e}\b[^>]*>`).join("|"),"i")});function ON({error:e}){let{classes:t}=Dy();return(0,Jt.jsx)("div",{className:t.errorBox,children:(0,Jt.jsx)(QE,{error:e})})}var Jt,Ty,pt,ky,Dy,GN,Ny,Ly=p(()=>{Jt=f(R(),1),Ty=f(M(),1);rf();pt=f(O(),1),ky=f(H(),1);wu();vE();Dd();Re();Dy=Y()(e=>({closeButton:{position:"absolute",right:e.spacing(1),top:e.spacing(1),color:e.palette.grey[500]},errorBox:{width:800,margin:40}}));GN=(0,ky.observer)(function(t){let{classes:r}=Dy(),{titleNode:n,...o}=t,{title:i,header:a,children:s,onClose:c}=o,l=(0,pt.useTheme)();return(0,Jt.jsx)(pt.Dialog,{...o,children:(0,Jt.jsxs)(pt.ScopedCssBaseline,{children:[(0,Ty.isValidElement)(a)?a:(0,Jt.jsxs)(pt.DialogTitle,{children:[n||(0,Jt.jsx)(Tn,{html:i||""}),c?(0,Jt.jsx)(pt.IconButton,{className:r.closeButton,onClick:A=>{c(A,"backdropClick")},children:(0,Jt.jsx)(Ic,{})}):null]}),(0,Jt.jsx)(pt.Divider,{}),(0,Jt.jsx)($o,{FallbackComponent:ON,children:(0,Jt.jsx)(pt.ThemeProvider,{theme:(0,pt.createTheme)(l,{components:{MuiInputBase:{styleOverrides:{input:{boxSizing:"content-box!important"}}}}}),children:s})})]})})}),Ny=GN});function Nd({onClose:e,helpText:t,label:r}){return(0,Eo.jsx)(Ny,{open:!0,onClose:e,title:"Help",titleNode:r?(0,Eo.jsxs)(Eo.Fragment,{children:["Help: ",r]}):void 0,onClick:n=>{n.stopPropagation()},onMouseDown:n=>{n.stopPropagation()},children:(0,Eo.jsx)(Ry.DialogContent,{children:t})})}var Eo,Ry,Fy=p(()=>{Eo=f(R(),1),Ry=f(O(),1);Ly()});function Ld({helpText:e,label:t}){let[r,n]=(0,nl.useState)(!1);return(0,ln.jsxs)(ln.Fragment,{children:[(0,ln.jsx)(Py.IconButton,{size:"small",onClick:o=>{o.stopPropagation(),n(!0)},style:{marginLeft:4,padding:4},children:(0,ln.jsx)(yC,{fontSize:"small"})}),r?(0,ln.jsxs)(nl.Suspense,{fallback:null,children:[(0,ln.jsx)(Nd,{helpText:e,label:t,onClose:o=>{o.stopPropagation(),n(!1)}})," "]}):null]})}var ln,nl,Py,Oy=p(()=>{ln=f(R(),1),nl=f(M(),1);wC();Py=f(O(),1);Fy()});var Gy,Uy,Hy,UN,jy,qy=p(()=>{Gy=f(R(),1),Uy=f(M(),1),Hy=f(O(),1),UN=Uy.forwardRef(function(t,r){return(0,Gy.jsx)(Hy.Menu,{...t,ref:r,style:{pointerEvents:"none",...t.style},slotProps:{...t.slotProps,paper:{style:{pointerEvents:"auto"}}}})}),jy=UN});var Jy,Vy,Yy=p(()=>{"use client";Gt();Jy=f(R(),1),Vy=(0,Ee.createSvgIcon)((0,Jy.jsx)("path",{d:"m10 17 5-5-5-5z"}),"ArrowRight")});var zy,Wy,$y=p(()=>{"use client";Gt();zy=f(R(),1),Wy=(0,Ee.createSvgIcon)((0,zy.jsx)("path",{d:"M19 3H5c-1.11 0-2 .9-2 2v14c0 1.1.89 2 2 2h14c1.11 0 2-.9 2-2V5c0-1.1-.89-2-2-2m-9 14-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8z"}),"CheckBox")});var Ky,Xy,Zy=p(()=>{"use client";Gt();Ky=f(R(),1),Xy=(0,Ee.createSvgIcon)((0,Ky.jsx)("path",{d:"M19 5v14H5V5zm0-2H5c-1.1 0-2 .9-2 2v14c0 1.1.9 2 2 2h14c1.1 0 2-.9 2-2V5c0-1.1-.9-2-2-2"}),"CheckBoxOutlineBlank")});var ew,tw,rw=p(()=>{"use client";Gt();ew=f(R(),1),tw=(0,Ee.createSvgIcon)((0,ew.jsx)("path",{d:"M12 7c-2.76 0-5 2.24-5 5s2.24 5 5 5 5-2.24 5-5-2.24-5-5-5m0-5C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m0 18c-4.42 0-8-3.58-8-8s3.58-8 8-8 8 3.58 8 8-3.58 8-8 8"}),"RadioButtonChecked")});var nw,ow,iw=p(()=>{"use client";Gt();nw=f(R(),1),ow=(0,Ee.createSvgIcon)((0,nw.jsx)("path",{d:"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m0 18c-4.42 0-8-3.58-8-8s3.58-8 8-8 8 3.58 8 8-3.58 8-8 8"}),"RadioButtonUnchecked")});function aw(e){let{classes:t}=HN(),{type:r}=e,n,o;"checked"in e&&({checked:n,disabled:o}=e);let i;switch(r){case"subMenu":{i=(0,kn.jsx)(Vy,{color:"action"});break}case"checkbox":{n?i=(0,kn.jsx)(Wy,{color:o?"inherit":void 0}):i=(0,kn.jsx)(Xy,{color:"action"});break}case"radio":{n?i=(0,kn.jsx)(tw,{color:o?"inherit":void 0}):i=(0,kn.jsx)(ow,{color:"action"});break}}return(0,kn.jsx)("div",{className:t.menuItemEndDecoration,children:i})}var kn,ol,HN,sw=p(()=>{kn=f(R(),1);Yy();$y();Zy();rw();iw();ol=f(O(),1);Re();HN=Y()({menuItemEndDecoration:{padding:0,margin:0,height:16}})});function cw(e){if(typeof e=="string")return e.toLowerCase().replace(/\s+/g,"_")}function jN({title:e,Icon:t,inset:r,menuItems:n,onMenuItemClick:o,closeAfterItemClick:i,onCloseRoot:a,isOpen:s,onOpen:c,onClose:l}){let[A,u]=(0,Rd.useState)(null),m=cw(e);return(0,ue.jsxs)(ue.Fragment,{children:[(0,ue.jsxs)(vt.MenuItem,{ref:u,"data-testid":m?`cascading-submenu-${m}`:void 0,onMouseOver:c,onFocus:c,onClick:c,children:[t?(0,ue.jsx)(vt.ListItemIcon,{children:(0,ue.jsx)(t,{})}):null,(0,ue.jsx)(vt.ListItemText,{primary:e,inset:r}),(0,ue.jsx)(EC,{})]}),(0,ue.jsx)(jy,{open:s,anchorEl:A,onClose:l,anchorOrigin:{vertical:"top",horizontal:"right"},transformOrigin:{vertical:"top",horizontal:"left"},children:(0,ue.jsx)(lw,{closeAfterItemClick:i,onMenuItemClick:o,menuItems:n,onCloseRoot:a})})]})}function lw({onMenuItemClick:e,closeAfterItemClick:t,menuItems:r,onCloseRoot:n}){let[o,i]=(0,Rd.useState)(),a=()=>{i(void 0)},s=r.some(A=>"icon"in A&&A.icon),c=r.some(A=>(A.type==="checkbox"||A.type==="radio")&&"helpText"in A&&A.helpText),l=r.toSorted((A,u)=>(u.priority||0)-(A.priority||0));return(0,ue.jsx)(ue.Fragment,{children:l.map((A,u)=>{if("subMenu"in A)return(0,ue.jsx)(jN,{title:A.label,Icon:A.icon,inset:s&&!A.icon,onMenuItemClick:e,menuItems:A.subMenu,closeAfterItemClick:t,onCloseRoot:n,isOpen:o===u,onOpen:()=>{i(u)},onClose:a},`subMenu-${A.label}-${u}`);if(A.type==="divider")return(0,ue.jsx)(vt.Divider,{component:"li"},`divider-${u}`);if(A.type==="subHeader")return(0,ue.jsx)(vt.ListSubheader,{children:A.label},`subHeader-${A.label}-${u}`);let m=A,d=m.helpText,g=m.type==="checkbox"||m.type==="radio",C=cw(m.label);return(0,ue.jsxs)(vt.MenuItem,{"data-testid":C?`cascading-menuitem-${C}`:void 0,disabled:!!m.disabled,onClick:y=>{t&&n(),e(y,m.onClick)},onMouseOver:a,children:[m.icon?(0,ue.jsx)(vt.ListItemIcon,{children:(0,ue.jsx)(m.icon,{})}):null,(0,ue.jsx)(vt.ListItemText,{primary:m.label,secondary:m.subLabel,inset:s&&!m.icon}),(0,ue.jsx)("div",{style:{flexGrow:1,minWidth:10}}),g?(0,ue.jsx)(aw,{type:m.type,checked:m.checked,disabled:m.disabled}):null,d?(0,ue.jsx)(Ld,{helpText:d,label:m.label}):g&&c?(0,ue.jsx)("div",{style:{marginLeft:4,padding:4,width:28,height:28}}):null]},`${m.label}-${u}`)})})}function Fd({onMenuItemClick:e,closeAfterItemClick:t=!0,menuItems:r,open:n,onClose:o,anchorEl:i,anchorOrigin:a,transformOrigin:s,anchorReference:c,anchorPosition:l,slotProps:A,marginThreshold:u,style:m}){let d=Array.isArray(r)?r:r();return(0,ue.jsx)(vt.Menu,{anchorEl:i,open:n,onClose:o,anchorOrigin:a,transformOrigin:s,anchorReference:c,anchorPosition:l,slotProps:A,marginThreshold:u??void 0,style:m,children:(0,ue.jsx)(lw,{menuItems:d,closeAfterItemClick:t,onMenuItemClick:e,onCloseRoot:o})})}var ue,Rd,vt,Aw=p(()=>{ue=f(R(),1),Rd=f(M(),1);IC();vt=f(O(),1);Oy();qy();sw()});function qN({children:e,menuItems:t,closeAfterItemClick:r=!0,stopPropagation:n,disabled:o,setOpen:i,ButtonComponent:a=uw.IconButton,onClick:s,anchorOrigin:c,transformOrigin:l,marginThreshold:A,...u}){let[m,d]=(0,il.useState)(null),g=!!m;(0,il.useEffect)(()=>{i?.(g)},[g,i]);let C=o??(Array.isArray(t)&&t.length===0);return(0,Io.jsxs)(Io.Fragment,{children:[(0,Io.jsx)(a,{onClick:y=>{n&&y.stopPropagation(),d(y.currentTarget),s?.(y)},...u,disabled:C,children:e}),g?(0,Io.jsx)(Fd,{open:g,onClose:()=>{d(null)},anchorEl:m,anchorOrigin:c,transformOrigin:l,marginThreshold:A,menuItems:t,closeAfterItemClick:r,onMenuItemClick:(y,I)=>{I()}}):null]})}var Io,il,uw,Pr,Li=p(()=>{Io=f(R(),1),il=f(M(),1),uw=f(O(),1);Aw();Pr=qN});var fw,dw,mw=p(()=>{"use client";me();fw=f(R(),1),dw=(0,j.createSvgIcon)((0,fw.jsx)("path",{d:"M12 2C6.49 2 2 6.49 2 12s4.49 10 10 10c1.38 0 2.5-1.12 2.5-2.5 0-.61-.23-1.2-.64-1.67-.08-.1-.13-.21-.13-.33 0-.28.22-.5.5-.5H16c3.31 0 6-2.69 6-6 0-4.96-4.49-9-10-9m5.5 11c-.83 0-1.5-.67-1.5-1.5s.67-1.5 1.5-1.5 1.5.67 1.5 1.5-.67 1.5-1.5 1.5m-3-4c-.83 0-1.5-.67-1.5-1.5S13.67 6 14.5 6s1.5.67 1.5 1.5S15.33 9 14.5 9M5 11.5c0-.83.67-1.5 1.5-1.5s1.5.67 1.5 1.5S7.33 13 6.5 13 5 12.33 5 11.5m6-4c0 .83-.67 1.5-1.5 1.5S8 8.33 8 7.5 8.67 6 9.5 6s1.5.67 1.5 1.5"}),"Palette")});var JN,al,pw=p(()=>{JN={50:"#ffebee",100:"#ffcdd2",200:"#ef9a9a",300:"#e57373",400:"#ef5350",500:"#f44336",600:"#e53935",700:"#d32f2f",800:"#c62828",900:"#b71c1c",A100:"#ff8a80",A200:"#ff5252",A400:"#ff1744",A700:"#d50000"},al=JN});var VN,Pd,gw=p(()=>{VN={50:"#e3f2fd",100:"#bbdefb",200:"#90caf9",300:"#64b5f6",400:"#42a5f5",500:"#2196f3",600:"#1e88e5",700:"#1976d2",800:"#1565c0",900:"#0d47a1",A100:"#82b1ff",A200:"#448aff",A400:"#2979ff",A700:"#2962ff"},Pd=VN});var YN,Od,hw=p(()=>{YN={50:"#e8f5e9",100:"#c8e6c9",200:"#a5d6a7",300:"#81c784",400:"#66bb6a",500:"#4caf50",600:"#43a047",700:"#388e3c",800:"#2e7d32",900:"#1b5e20",A100:"#b9f6ca",A200:"#69f0ae",A400:"#00e676",A700:"#00c853"},Od=YN});var zN,Gd,Cw=p(()=>{zN={50:"#fff3e0",100:"#ffe0b2",200:"#ffcc80",300:"#ffb74d",400:"#ffa726",500:"#ff9800",600:"#fb8c00",700:"#f57c00",800:"#ef6c00",900:"#e65100",A100:"#ffd180",A200:"#ffab40",A400:"#ff9100",A700:"#ff6d00"},Gd=zN});var Ew=p(()=>{pw();gw();hw();Cw()});var Iw,WN,za,Ud=p(()=>{Ew();la();su();xn();Os([Gs]);Iw={A:Od[500],C:Pd[500],G:Gd[500],T:al[500],U:al[500]},WN={none:{},nucleotide:Iw,clustal:{G:"orange",P:"orange",S:"orange",T:"orange",H:"red",K:"red",R:"red",F:"blue",W:"blue",Y:"blue",I:"green",L:"green",M:"green",V:"green"},lesk:{G:"orange",A:"orange",S:"orange",T:"orange",C:"green",V:"green",I:"green",L:"green",P:"green",F:"green",Y:"green",M:"green",W:"green",N:"magenta",Q:"magenta",H:"magenta",D:"red",E:"red",K:"blue",R:"blue"},maeditor:{A:"lightgreen",G:"lightgreen",C:"green",D:"darkgreen",E:"darkgreen",N:"darkgreen",Q:"darkgreen",I:"blue",L:"blue",M:"blue",V:"blue",F:"#c8a2c8",W:"#c8a2c8",Y:"#c8a2c8",H:"darkblue",K:"orange",R:"orange",P:"pink",S:"red",T:"red"},percent_identity_dynamic:{},flower:{A:"#b18a51",C:"#ff5701",D:"#01a578",E:"#2da0a1",F:"#fa559d",G:"#b1c23c",H:"#0194f9",I:"#f27663",K:"#7fc3d7",L:"#df6e75",M:"#fe9daf",N:"#0bcec6",P:"#4fa32a",Q:"#7295ae",R:"#83bff1",S:"#b4bd9b",T:"#d2b576",V:"#fd997b",W:"#ff2ded",Y:"#c96ecf"},rainbow_dna:{A:"#3737f5",C:"#37f537",G:"#f5f537",T:"#f53737",U:"#f53737"},clustalx_protein:{A:"#197fe5",C:"#e57f7f",D:"#cc4ccc",E:"#cc4ccc",F:"#197fe5",G:"#e5994c",H:"#19b2b2",I:"#197fe5",K:"#e53319",L:"#197fe5",M:"#197fe5",N:"#19cc19",P:"#cccc00",Q:"#19cc19",R:"#e53319",S:"#19cc19",T:"#19cc19",V:"#197fe5",W:"#197fe5",Y:"#19b2b2"},clustalx_protein_dynamic:{},clustalx_dna:{A:"#e53319",C:"#197fe5",G:"#e5994c",T:"#19cc19",U:"#19cc19"},jbrowse_dna:Iw,jalview_buried:{A:"#00a35c",R:"#00fc03",N:"#00eb14",D:"#00eb14",C:"#0000ff",Q:"#00f10e",E:"#00f10e",G:"#009d62",H:"#00d52a",I:"#0054ab",L:"#007b84",K:"#00ff00",M:"#009768",F:"#008778",P:"#00e01f",S:"#00d52a",T:"#00db24",W:"#00a857",Y:"#00e619",V:"#005fa0",B:"#00eb14",X:"#00b649",Z:"#00f10e"},jalview_hydrophobicity:{A:"#ad0052",R:"#0000ff",N:"#0c00f3",D:"#0c00f3",C:"#c2003d",Q:"#0c00f3",E:"#0c00f3",G:"#6a0095",H:"#1500ea",I:"#ff0000",L:"#ea0015",K:"#0000ff",M:"#b0004f",F:"#cb0034",P:"#4600b9",S:"#5e00a1",T:"#61009e",W:"#5b00a4",Y:"#4f00b0",V:"#f60009",B:"#0c00f3",X:"#680097",Z:"#0c00f3"},jalview_prophelix:{A:"#e718e7",R:"#6f906f",N:"#1be41b",D:"#778877",C:"#23dc23",Q:"#926d92",E:"#ff00ff",G:"#00ff00",H:"#758a75",I:"#8a758a",L:"#ae51ae",K:"#a05fa0",M:"#ef10ef",F:"#986798",P:"#00ff00",S:"#36c936",T:"#47b847",W:"#8a758a",Y:"#21de21",V:"#857a85",B:"#49b649",X:"#758a75",Z:"#c936c9"},jalview_propstrand:{A:"#5858a7",R:"#6b6b94",N:"#64649b",D:"#2121de",C:"#9d9d62",Q:"#8c8c73",E:"#0000ff",G:"#4949b6",H:"#60609f",I:"#ecec13",L:"#b2b24d",K:"#4747b8",M:"#82827d",F:"#c2c23d",P:"#2323dc",S:"#4949b6",T:"#9d9d62",W:"#c0c03f",Y:"#d3d32c",V:"#ffff00",B:"#4343bc",X:"#797986",Z:"#4747b8"},jalview_propturn:{A:"#2cd3d3",R:"#708f8f",N:"#ff0000",D:"#e81717",C:"#a85757",Q:"#3fc0c0",E:"#778888",G:"#ff0000",H:"#708f8f",I:"#00ffff",L:"#1ce3e3",K:"#7e8181",M:"#1ee1e1",F:"#1ee1e1",P:"#f60909",S:"#e11e1e",T:"#738c8c",W:"#738c8c",Y:"#9d6262",V:"#07f8f8",B:"#f30c0c",X:"#7c8383",Z:"#5ba4a4"},jalview_taylor:{A:"#ccff00",R:"#0000ff",N:"#cc00ff",D:"#ff0000",C:"#ffff00",Q:"#ff00cc",E:"#ff0066",G:"#ff9900",H:"#0066ff",I:"#66ff00",L:"#33ff00",K:"#6600ff",M:"#00ff00",F:"#00ff66",P:"#ffcc00",S:"#ff3300",T:"#ff6600",W:"#00ccff",Y:"#00ffcc",V:"#99ff00"},jalview_zappo:{A:"#ffafaf",R:"#6464ff",N:"#00ff00",D:"#ff0000",C:"#ffff00",Q:"#00ff00",E:"#ff0000",G:"#ff00ff",H:"#6464ff",I:"#ffafaf",L:"#ffafaf",K:"#6464ff",M:"#ffafaf",F:"#ffc800",P:"#ff00ff",S:"#00ff00",T:"#00ff00",W:"#ffc800",Y:"#ffc800",V:"#ffafaf"},cinema:{H:"blue",K:"blue",R:"blue",D:"red",E:"red",S:"green",T:"green",N:"green",Q:"green",A:"white",V:"white",L:"white",I:"white",M:"white",F:"magenta",W:"magenta",Y:"magenta",P:"brown",G:"brown",C:"yellow",B:"gray",Z:"gray",X:"gray","-":"gray",".":"gray"}},za=Wo(WN,([e,t])=>[e,Wo(t,([r,n])=>[r,Je(n).toHex()])])});var Hd,xw,$N,yw,ww=p(()=>{Hd=f(M(),1);Li();mw();xw=f(H(),1);Ud();$N=(0,xw.observer)(function({model:e}){let{colorSchemeName:t}=e;return Hd.default.createElement(Pr,{"data-testid":"color_scheme_menu",tooltip:"Color scheme",closeAfterItemClick:!0,anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"},menuItems:Object.keys(za).map(r=>({label:r,type:"radio",checked:t===r,onClick:()=>{e.setColorSchemeName(r)}}))},Hd.default.createElement(dw,null))}),yw=$N});var bw,Bw,Sw=p(()=>{"use client";me();bw=f(R(),1),Bw=(0,j.createSvgIcon)((0,bw.jsx)("path",{d:"M19 3h-4.18C14.4 1.84 13.3 1 12 1s-2.4.84-2.82 2H5c-1.1 0-2 .9-2 2v14c0 1.1.9 2 2 2h14c1.1 0 2-.9 2-2V5c0-1.1-.9-2-2-2m-7 0c.55 0 1 .45 1 1s-.45 1-1 1-1-.45-1-1 .45-1 1-1m2 14H7v-2h7zm3-4H7v-2h10zm0-4H7V7h10z"}),"Assignment")});var Qw,sl,jd=p(()=>{"use client";me();Qw=f(R(),1),sl=(0,j.createSvgIcon)((0,Qw.jsx)("path",{d:"M20 6h-8l-2-2H4c-1.1 0-1.99.9-1.99 2L2 18c0 1.1.9 2 2 2h16c1.1 0 2-.9 2-2V8c0-1.1-.9-2-2-2m0 12H4V8h16z"}),"FolderOpen")});var vw,Mw,_w=p(()=>{"use client";me();vw=f(R(),1),Mw=(0,j.createSvgIcon)((0,vw.jsx)("path",{d:"M3 18h18v-2H3zm0-5h18v-2H3zm0-7v2h18V6z"}),"Menu")});var qd,Tw,kw=p(()=>{"use client";me();qd=f(R(),1),Tw=(0,j.createSvgIcon)([(0,qd.jsx)("circle",{cx:"12",cy:"12",r:"3.2"},"0"),(0,qd.jsx)("path",{d:"M9 2 7.17 4H4c-1.1 0-2 .9-2 2v12c0 1.1.9 2 2 2h16c1.1 0 2-.9 2-2V6c0-1.1-.9-2-2-2h-3.17L15 2zm3 15c-2.76 0-5-2.24-5-5s2.24-5 5-5 5 2.24 5 5-2.24 5-5 5"},"1")],"PhotoCamera")});var Dw,Nw,Lw=p(()=>{"use client";me();Dw=f(R(),1),Nw=(0,j.createSvgIcon)((0,Dw.jsx)("path",{d:"M4.25 5.61C6.27 8.2 10 13 10 13v6c0 .55.45 1 1 1h2c.55 0 1-.45 1-1v-6s3.72-4.8 5.74-7.39c.51-.66.04-1.61-.79-1.61H5.04c-.83 0-1.3.95-.79 1.61"}),"FilterAlt")});var Rw,Fw,Pw=p(()=>{"use client";me();Rw=f(R(),1),Fw=(0,j.createSvgIcon)((0,Rw.jsx)("path",{d:"M15.5 14h-.79l-.28-.27C15.41 12.59 16 11.11 16 9.5 16 5.91 13.09 3 9.5 3S3 5.91 3 9.5 5.91 16 9.5 16c1.61 0 3.09-.59 4.23-1.57l.27.28v.79l5 4.99L20.49 19zm-6 0C7.01 14 5 11.99 5 9.5S7.01 5 9.5 5 14 7.01 14 9.5 11.99 14 9.5 14"}),"Search")});var Ow,Gw,Uw=p(()=>{"use client";me();Ow=f(R(),1),Gw=(0,j.createSvgIcon)((0,Ow.jsx)("path",{d:"M3 18h6v-2H3zM3 6v2h18V6zm0 7h12v-2H3z"}),"Sort")});var Hw,jw,qw=p(()=>{"use client";me();Hw=f(R(),1),jw=(0,j.createSvgIcon)((0,Hw.jsx)("path",{d:"M12 4.5C7 4.5 2.73 7.61 1 12c1.73 4.39 6 7.5 11 7.5s9.27-3.11 11-7.5c-1.73-4.39-6-7.5-11-7.5M12 17c-2.76 0-5-2.24-5-5s2.24-5 5-5 5 2.24 5 5-2.24 5-5 5m0-8c-1.66 0-3 1.34-3 3s1.34 3 3 3 3-1.34 3-3-1.34-3-3-3"}),"Visibility")});var Vw={};dt(Vw,{default:()=>eL});var ie,Jw,ae,cl,KN,XN,ZN,eL,Yw=p(()=>{ie=f(M(),1),Jw=f(Ne(),1),ae=f(O(),1),cl=f(H(),1),KN=(0,cl.observer)(function({model:e}){let{featureFilters:t}=e;return ie.default.createElement("div",null,ie.default.createElement(ae.Button,{onClick:()=>{for(let r of t.keys())e.setFilter(r,!0)}},"Toggle all on"),ie.default.createElement(ae.Button,{onClick:()=>{for(let r of t.keys())e.setFilter(r,!1)}},"Toggle all off"))}),XN=(0,cl.observer)(function({model:e}){let{tidyInterProAnnotationTypes:t,tidyInterProAnnotations:r,fillPalette:n}=e,o=new Map;for(let i of r)o.set(i.accession,(o.get(i.accession)??0)+1);return ie.default.createElement(ie.default.Fragment,null,ie.default.createElement(KN,{model:e}),ie.default.createElement(ae.Table,{size:"small"},ie.default.createElement(ae.TableHead,null,ie.default.createElement(ae.TableRow,null,ie.default.createElement(ae.TableCell,{padding:"checkbox"}),ie.default.createElement(ae.TableCell,null,"color"),ie.default.createElement(ae.TableCell,null,"accession"),ie.default.createElement(ae.TableCell,null,"name"),ie.default.createElement(ae.TableCell,null,"count"),ie.default.createElement(ae.TableCell,null,"description"))),ie.default.createElement(ae.TableBody,null,[...t.values()].map(({accession:i,name:a,description:s})=>ie.default.createElement(ae.TableRow,{key:i},ie.default.createElement(ae.TableCell,{padding:"checkbox"},ie.default.createElement(ae.Checkbox,{checked:e.featureFilters.get(i)??!1,onChange:()=>{e.setFilter(i,!e.featureFilters.get(i))}})),ie.default.createElement(ae.TableCell,null,ie.default.createElement("div",{style:{width:20,height:20,background:n[i]}})),ie.default.createElement(ae.TableCell,null,i),ie.default.createElement(ae.TableCell,null,a),ie.default.createElement(ae.TableCell,null,o.get(i)),ie.default.createElement(ae.TableCell,null,s))))))}),ZN=(0,cl.observer)(function({onClose:e,model:t}){return ie.default.createElement(Jw.Dialog,{onClose:()=>{e()},open:!0,title:"Feature filters",maxWidth:"xl"},ie.default.createElement(ae.DialogContent,null,ie.default.createElement(XN,{model:t})))}),eL=ZN});async function Wa(e,t,r=ll.fetchAndMaybeUnzipText){let n=new AbortController;try{return await r(e,{signal:n.signal,statusCallback:o=>{let i=(0,ll.statusMessageText)(o);t(i?{msg:i,onCancel:()=>{n.abort()}}:void 0)}})}finally{t(void 0)}}async function zw(e,t){let r=await fetch(e,t);if(!r.ok)throw new Error(`HTTP ${r.status} fetching ${e} ${await r.text()}`);return r}async function Jd(e,t){return(await zw(e,t)).text()}async function Al(e,t){return(await zw(e,t)).json()}function Ww(e,t){return new Promise((r,n)=>{if(t?.aborted)n(new DOMException("Aborted","AbortError"));else{let o=setTimeout(r,e);t?.addEventListener("abort",()=>{clearTimeout(o),n(new DOMException("Aborted","AbortError"))})}})}function Dn(e){return e instanceof DOMException&&e.name==="AbortError"}var ll,ul=p(()=>{ll=f(de(),1)});var Xw={};dt(Xw,{default:()=>rL});var xe,$w,Vd,ve,Kw,tL,rL,Zw=p(()=>{xe=f(M(),1),$w=f(Ne(),1),Vd=f(de(),1),ve=f(O(),1),Kw=f(H(),1);ul();tL=(0,Kw.observer)(function({handleClose:e,model:t}){let[r,n]=(0,xe.useState)(),[o,i]=(0,xe.useState)("file"),[a,s]=(0,xe.useState)("");return xe.default.createElement($w.Dialog,{maxWidth:"xl",title:"Open protein domains from file",onClose:()=>{e()},open:!0},xe.default.createElement(ve.DialogContent,null,xe.default.createElement("div",null,xe.default.createElement(ve.Typography,null,"Open a JSON file of InterProScan results that you run remotely on EBI servers or locally"),xe.default.createElement("div",{style:{display:"flex",margin:30}},xe.default.createElement(ve.FormControl,{component:"fieldset"},xe.default.createElement(ve.RadioGroup,{value:o,onChange:c=>{i(c.target.value)}},xe.default.createElement(ve.FormControlLabel,{value:"url",control:xe.default.createElement(ve.Radio,null),label:"URL"}),xe.default.createElement(ve.FormControlLabel,{value:"file",control:xe.default.createElement(ve.Radio,null),label:"File"}))),o==="url"?xe.default.createElement("div",null,xe.default.createElement(ve.Typography,null,"Open a InterProScan JSON file remote URL"),xe.default.createElement(ve.TextField,{label:"URL",value:a,onChange:c=>{s(c.target.value)}})):null,o==="file"?xe.default.createElement("div",{style:{paddingTop:20}},xe.default.createElement(ve.Typography,null,"Open a InterProScan JSON file file from your local drive"),xe.default.createElement(ve.Button,{variant:"outlined",component:"label"},"Choose File",xe.default.createElement("input",{type:"file",hidden:!0,onChange:({target:c})=>{let l=c.files?.[0];l&&n(l)}}))):null))),xe.default.createElement(ve.DialogActions,null,xe.default.createElement(ve.Button,{variant:"contained",color:"primary",onClick:()=>{(async()=>{try{let c=r?JSON.parse(await r.text()):await Al(a);t.setDomains(Object.fromEntries(c.results.map(l=>[l.xref[0].id,l]))),(0,Vd.getSession)(t).notify("Loaded interproscan results","success")}catch(c){console.error(c),(0,Vd.getSession)(t).notifyError(`${c}`,c)}finally{t.setStatus()}})(),e()}},"Open results")))}),rL=tL});var eb=p(()=>{});function Ri(e,t="node",r=0){let n=`${t}-${r}`;return{...e,id:n,name:e.name||n,children:e.children?.map((o,i)=>Ri(o,`${n}-${i}`,r+1))||[]}}var Yd=p(()=>{});var Vt,Fi=p(()=>{Vt=class{getTree(){return{id:"root",name:"root",noTree:!0,children:this.getNames().map(t=>({id:t,children:[],name:t}))}}getRowData(t){}getStructures(){return{}}getHeader(){return{}}get alignmentNames(){return[]}get seqConsensus(){}get secondaryStructureConsensus(){}get tracks(){return[]}}});function Pi(e){return e>=nL&&e<=oL}var tb,rb,nL,oL,nb,ob,An,zd=p(()=>{Fi();tb=65,rb=90,nL=97,oL=122,nb=45,ob=46;An=class extends Vt{MSA;orderedNames;constructor(t){super();let r=[],n=[];for(let o of t.split(">")){if(!/\S/.test(o))continue;let i=o.indexOf(`
+  `):"",this.name="UnsubscriptionError",this.errors=r}})});function Dg(e,t){if(e){var r=e.indexOf(t);0<=r&&e.splice(r,1)}}var kB=d(()=>{});function NB(e){return e instanceof hf||e&&"closed"in e&&dn(e.remove)&&dn(e.add)&&dn(e.unsubscribe)}function DB(e){dn(e)?e():e.unsubscribe()}var hf,Xee,RB=d(()=>{vc();mf();_B();kB();hf=(function(){function e(t){this.initialTeardown=t,this.closed=!1,this._parentage=null,this._finalizers=null}return e.prototype.unsubscribe=function(){var t,r,n,o,i;if(!this.closed){this.closed=!0;var a=this._parentage;if(a)if(this._parentage=null,Array.isArray(a))try{for(var s=_g(a),c=s.next();!c.done;c=s.next()){var l=c.value;l.remove(this)}}catch(y){t={error:y}}finally{try{c&&!c.done&&(r=s.return)&&r.call(s)}finally{if(t)throw t.error}}else a.remove(this);var u=this.initialTeardown;if(dn(u))try{u()}catch(y){i=y instanceof gf?y.errors:[y]}var A=this._finalizers;if(A){this._finalizers=null;try{for(var m=_g(A),f=m.next();!f.done;f=m.next()){var g=f.value;try{DB(g)}catch(y){i=i??[],y instanceof gf?i=Ha(Ha([],Ua(i)),Ua(y.errors)):i.push(y)}}}catch(y){n={error:y}}finally{try{f&&!f.done&&(o=m.return)&&o.call(m)}finally{if(n)throw n.error}}}if(i)throw new gf(i)}},e.prototype.add=function(t){var r;if(t&&t!==this)if(this.closed)DB(t);else{if(t instanceof e){if(t.closed||t._hasParent(this))return;t._addParent(this)}(this._finalizers=(r=this._finalizers)!==null&&r!==void 0?r:[]).push(t)}},e.prototype._hasParent=function(t){var r=this._parentage;return r===t||Array.isArray(r)&&r.includes(t)},e.prototype._addParent=function(t){var r=this._parentage;this._parentage=Array.isArray(r)?(r.push(t),r):r?[r,t]:t},e.prototype._removeParent=function(t){var r=this._parentage;r===t?this._parentage=null:Array.isArray(r)&&Dg(r,t)},e.prototype.remove=function(t){var r=this._finalizers;r&&Dg(r,t),t instanceof e&&t._removeParent(this)},e.EMPTY=(function(){var t=new e;return t.closed=!0,t})(),e})(),Xee=hf.EMPTY});var fo,Cf=d(()=>{fo={onUnhandledError:null,onStoppedNotification:null,Promise:void 0,useDeprecatedSynchronousErrorHandling:!1,useDeprecatedNextContext:!1}});var Va,Ng=d(()=>{vc();Va={setTimeout:function(e,t){for(var r=[],n=2;n<arguments.length;n++)r[n-2]=arguments[n];var o=Va.delegate;return o?.setTimeout?o.setTimeout.apply(o,Ha([e,t],Ua(r))):setTimeout.apply(void 0,Ha([e,t],Ua(r)))},clearTimeout:function(e){var t=Va.delegate;return(t?.clearTimeout||clearTimeout)(e)},delegate:void 0}});function LB(e){Va.setTimeout(function(){var t=fo.onUnhandledError;if(t)t(e);else throw e})}var FB=d(()=>{Cf();Ng()});function Rg(){}var PB=d(()=>{});function GB(e){return Lg("E",void 0,e)}function UB(e){return Lg("N",e,void 0)}function Lg(e,t,r){return{kind:e,value:t,error:r}}var OB,HB=d(()=>{OB=(function(){return Lg("C",void 0,void 0)})()});function VB(e){fo.useDeprecatedSynchronousErrorHandling&&Fg&&(Fg.errorThrown=!0,Fg.error=e)}var Fg,jB=d(()=>{Cf();Fg=null});function Pg(e,t){return n8.call(e,t)}function yf(e){fo.useDeprecatedSynchronousErrorHandling?VB(e):LB(e)}function i8(e){throw e}function Og(e,t){var r=fo.onStoppedNotification;r&&Va.setTimeout(function(){return r(e,t)})}var Gg,n8,o8,Ug,a8,Hg=d(()=>{vc();mf();RB();Cf();FB();PB();HB();Ng();jB();Gg=(function(e){Bc(t,e);function t(r){var n=e.call(this)||this;return n.isStopped=!1,r?(n.destination=r,NB(r)&&r.add(n)):n.destination=a8,n}return t.create=function(r,n,o){return new Ug(r,n,o)},t.prototype.next=function(r){this.isStopped?Og(UB(r),this):this._next(r)},t.prototype.error=function(r){this.isStopped?Og(GB(r),this):(this.isStopped=!0,this._error(r))},t.prototype.complete=function(){this.isStopped?Og(OB,this):(this.isStopped=!0,this._complete())},t.prototype.unsubscribe=function(){this.closed||(this.isStopped=!0,e.prototype.unsubscribe.call(this),this.destination=null)},t.prototype._next=function(r){this.destination.next(r)},t.prototype._error=function(r){try{this.destination.error(r)}finally{this.unsubscribe()}},t.prototype._complete=function(){try{this.destination.complete()}finally{this.unsubscribe()}},t})(hf),n8=Function.prototype.bind;o8=(function(){function e(t){this.partialObserver=t}return e.prototype.next=function(t){var r=this.partialObserver;if(r.next)try{r.next(t)}catch(n){yf(n)}},e.prototype.error=function(t){var r=this.partialObserver;if(r.error)try{r.error(t)}catch(n){yf(n)}else yf(t)},e.prototype.complete=function(){var t=this.partialObserver;if(t.complete)try{t.complete()}catch(r){yf(r)}},e})(),Ug=(function(e){Bc(t,e);function t(r,n,o){var i=e.call(this)||this,a;if(dn(r)||!r)a={next:r??void 0,error:n??void 0,complete:o??void 0};else{var s;i&&fo.useDeprecatedNextContext?(s=Object.create(r),s.unsubscribe=function(){return i.unsubscribe()},a={next:r.next&&Pg(r.next,s),error:r.error&&Pg(r.error,s),complete:r.complete&&Pg(r.complete,s)}):a=r}return i.destination=new o8(a),i}return t})(Gg);a8={closed:!0,next:Rg,error:i8,complete:Rg}});function s8(e){return dn(e?.lift)}function xf(e){return function(t){if(s8(t))return t.lift(function(r){try{return e(r,this)}catch(n){this.error(n)}});throw new TypeError("Unable to lift unknown Observable type")}}var Vg=d(()=>{mf()});function YB(e,t,r,n,o){return new c8(e,t,r,n,o)}var c8,$B=d(()=>{vc();Hg();c8=(function(e){Bc(t,e);function t(r,n,o,i,a,s){var c=e.call(this,r)||this;return c.onFinalize=a,c.shouldUnsubscribe=s,c._next=n?function(l){try{n(l)}catch(u){r.error(u)}}:e.prototype._next,c._error=i?function(l){try{i(l)}catch(u){r.error(u)}finally{this.unsubscribe()}}:e.prototype._error,c._complete=o?function(){try{o()}catch(l){r.error(l)}finally{this.unsubscribe()}}:e.prototype._complete,c}return t.prototype.unsubscribe=function(){var r;if(!this.shouldUnsubscribe||this.shouldUnsubscribe()){var n=this.closed;e.prototype.unsubscribe.call(this),!n&&((r=this.onFinalize)===null||r===void 0||r.call(this))}},t})(Gg)});var qB,JB=d(()=>{kg();qB=pf(function(e){return function(){e(this),this.name="EmptyError",this.message="no elements in sequence"}})});function jg(e,t){var r=typeof t=="object";return new Promise(function(n,o){var i=new Ug({next:function(a){n(a),i.unsubscribe()},error:o,complete:function(){r?n(t.defaultValue):o(new qB)}});e.subscribe(i)})}var WB=d(()=>{JB();Hg()});var zB=d(()=>{});function KB(e,t,r,n,o){return function(i,a){var s=r,c=t,l=0;i.subscribe(YB(a,function(u){var A=l++;c=s?e(c,u,A):(s=!0,u),n&&a.next(c)},o&&(function(){s&&a.next(c),a.complete()})))}}var XB=d(()=>{$B()});function ZB(e,t){return xf(KB(e,t,arguments.length>=2,!1,!0))}var ev=d(()=>{XB();Vg()});function Yg(){return xf(function(e,t){ZB(l8,[])(e).subscribe(t)})}var l8,tv=d(()=>{ev();Vg();l8=function(e,t){return e.push(t),e}});var rv=d(()=>{WB();zB();tv()});var nv=d(()=>{});var ov=d(()=>{});function u8(){return iv||(iv=[IDBDatabase,IDBObjectStore,IDBIndex,IDBCursor,IDBTransaction])}function f8(){return av||(av=[IDBCursor.prototype.advance,IDBCursor.prototype.continue,IDBCursor.prototype.continuePrimaryKey])}function A8(e){let t=new Promise((r,n)=>{let o=()=>{e.removeEventListener("success",i),e.removeEventListener("error",a)},i=()=>{r(fi(e.result)),o()},a=()=>{n(e.error),o()};e.addEventListener("success",i),e.addEventListener("error",a)});return Ef.set(t,e),t}function d8(e){if(Wg.has(e))return;let t=new Promise((r,n)=>{let o=()=>{e.removeEventListener("complete",i),e.removeEventListener("error",a),e.removeEventListener("abort",a)},i=()=>{r(),o()},a=()=>{n(e.error||new DOMException("AbortError","AbortError")),o()};e.addEventListener("complete",i),e.addEventListener("error",a),e.addEventListener("abort",a)});Wg.set(e,t)}function uv(e){zg=e(zg)}function m8(e){return f8().includes(e)?function(...t){return e.apply(Kg(this),t),fi(this.request)}:function(...t){return fi(e.apply(Kg(this),t))}}function p8(e){return typeof e=="function"?m8(e):(e instanceof IDBTransaction&&d8(e),Jg(e,u8())?new Proxy(e,zg):e)}function fi(e){if(e instanceof IDBRequest)return A8(e);if($g.has(e))return $g.get(e);let t=p8(e);return t!==e&&($g.set(e,t),Ef.set(t,e)),t}function Vn(e,t,{blocked:r,upgrade:n,blocking:o,terminated:i}={}){let a=indexedDB.open(e,t),s=fi(a);return n&&a.addEventListener("upgradeneeded",c=>{n(fi(a.result),c.oldVersion,c.newVersion,fi(a.transaction),c)}),r&&a.addEventListener("blocked",c=>r(c.oldVersion,c.newVersion,c)),s.then(c=>{i&&c.addEventListener("close",()=>i()),o&&c.addEventListener("versionchange",l=>o(l.oldVersion,l.newVersion,l))}).catch(()=>{}),s}function sv(e,t){if(!(e instanceof IDBDatabase&&!(t in e)&&typeof t=="string"))return;if(qg.get(t))return qg.get(t);let r=t.replace(/FromIndex$/,""),n=t!==r,o=h8.includes(r);if(!(r in(n?IDBIndex:IDBObjectStore).prototype)||!(o||g8.includes(r)))return;let i=async function(a,...s){let c=this.transaction(a,o?"readwrite":"readonly"),l=c.store;return n&&(l=l.index(s.shift())),(await Promise.all([l[r](...s),o&&c.done]))[0]};return qg.set(t,i),i}async function*x8(...e){let t=this;if(t instanceof IDBCursor||(t=await t.openCursor(...e)),!t)return;t=t;let r=new Proxy(t,y8);for(fv.set(r,t),Ef.set(r,Kg(t));t;)yield r,t=await(Xg.get(r)||t.continue()),Xg.delete(r)}function lv(e,t){return t===Symbol.asyncIterator&&Jg(e,[IDBIndex,IDBObjectStore,IDBCursor])||t==="iterate"&&Jg(e,[IDBIndex,IDBObjectStore])}var Jg,iv,av,Wg,$g,Ef,zg,Kg,g8,h8,qg,C8,cv,Xg,fv,y8,ja=d(()=>{Jg=(e,t)=>t.some(r=>e instanceof r);Wg=new WeakMap,$g=new WeakMap,Ef=new WeakMap;zg={get(e,t,r){if(e instanceof IDBTransaction){if(t==="done")return Wg.get(e);if(t==="store")return r.objectStoreNames[1]?void 0:r.objectStore(r.objectStoreNames[0])}return fi(e[t])},set(e,t,r){return e[t]=r,!0},has(e,t){return e instanceof IDBTransaction&&(t==="done"||t==="store")?!0:t in e}};Kg=e=>Ef.get(e);g8=["get","getKey","getAll","getAllKeys","count"],h8=["put","add","delete","clear"],qg=new Map;uv(e=>({...e,get:(t,r,n)=>sv(t,r)||e.get(t,r,n),has:(t,r)=>!!sv(t,r)||e.has(t,r)}));C8=["continue","continuePrimaryKey","advance"],cv={},Xg=new WeakMap,fv=new WeakMap,y8={get(e,t){if(!C8.includes(t))return e[t];let r=cv[t];return r||(r=cv[t]=function(...n){Xg.set(this,fv.get(this)[t](...n))}),r}};uv(e=>({...e,get(t,r,n){return lv(t,r)?x8:e.get(t,r,n)},has(t,r){return lv(t,r)||e.has(t,r)}}))});var Av=d(()=>{ja()});var bf,dv=d(()=>{bf=p(Vt(),1)});function eh(e,t=10){let r=String(e),n=0;for(let o=0,i=r.length;o<i;o++)n+=I8[r.charCodeAt(o)]??w8;return n*t}function th(e){let t=0;if(e.length===0)return t;for(let r=0;r<e.length;r++){let n=e.charCodeAt(r);t=(t<<5)-t+n,t|=0}return t}function S8(e){let{uri:t,baseUri:r=""}=e,n;try{n=new URL(t,r).href}catch{n=t}return n}function rh(e){return Ir(e)?uf(e)?S8(e):JSON.stringify(e):String(e)}function mv(e){let t=/(^|[\s\n]|<[A-Za-z]*\/?>)((?:https?|ftp):\/\/[-A-Z0-9+\u0026\u2019@#/%?=()~_|!:,.;]*[-A-Z0-9+\u0026@#/%=~()_|])/gi;return e.replaceAll(t,`$1<a href='$2' target="_blank">$2</a>`)}function pv(e,t){let{padding:r=30,minWidth:n=80,fontSize:o=12,maxWidth:i=1e3,stripHTML:a=!1}=t||{};return nh(e.map(s=>rh(s)).map(s=>a?dB(s):s).map(s=>eh(s,o)).map(s=>Math.min(Math.max(s+r,n),i)))}function nh(e,t=Number.NEGATIVE_INFINITY){let r=t;for(let n of e)r=Math.max(n,r);return r}function Ir(e){return typeof e=="object"&&e!==null}var Zg,Ya,E8,b8,tre,rre,nre,ore,I8,w8,Ao=d(()=>{Zg=p(k(),1);wg();Ya=p(Vt(),1),E8=p(uB(),1),b8=p(AB(),1);Sg();Bg();Bg();hB();CB();yB();Sg();vB();TB();QB();MB();nv();ov();mB();pB();dv();Av();tre=180/Math.PI,rre=Math.PI/180,nre=/electron/i.test(typeof navigator<"u"?navigator.userAgent:""),ore=typeof jest>"u"?typeof window<"u"&&window.requestIdleCallback?window.requestIdleCallback:e=>setTimeout(()=>{e()},1):e=>{e()},I8=[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,.2796875,.2765625,.3546875,.5546875,.5546875,.8890625,.665625,.190625,.3328125,.3328125,.3890625,.5828125,.2765625,.3328125,.2765625,.3015625,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.5546875,.2765625,.2765625,.584375,.5828125,.584375,.5546875,1.0140625,.665625,.665625,.721875,.721875,.665625,.609375,.7765625,.721875,.2765625,.5,.665625,.5546875,.8328125,.721875,.7765625,.665625,.7765625,.721875,.665625,.609375,.721875,.665625,.94375,.665625,.665625,.609375,.2765625,.3546875,.2765625,.4765625,.5546875,.3328125,.5546875,.5546875,.5,.5546875,.5546875,.2765625,.5546875,.5546875,.221875,.240625,.5,.221875,.8328125,.5546875,.5546875,.5546875,.5546875,.3328125,.5,.2765625,.5546875,.5,.721875,.5,.5,.5,.3546875,.259375,.353125,.5890625],w8=.5279276315789471});function gv(e,t){(t==null||t>e.length)&&(t=e.length);for(var r=0,n=Array(t);r<t;r++)n[r]=e[r];return n}function B8(e){if(Array.isArray(e))return e}function v8(e,t){var r=e==null?null:typeof Symbol<"u"&&e[Symbol.iterator]||e["@@iterator"];if(r!=null){var n,o,i,a,s=[],c=!0,l=!1;try{if(i=(r=r.call(e)).next,t!==0)for(;!(c=(n=i.call(r)).done)&&(s.push(n.value),s.length!==t);c=!0);}catch(u){l=!0,o=u}finally{try{if(!c&&r.return!=null&&(a=r.return(),Object(a)!==a))return}finally{if(l)throw o}}return s}}function T8(){throw new TypeError(`Invalid attempt to destructure non-iterable instance.
+In order to be iterable, non-array objects must have a [Symbol.iterator]() method.`)}function Q8(e,t){return B8(e)||v8(e,t)||M8(e,t)||T8()}function M8(e,t){if(e){if(typeof e=="string")return gv(e,t);var r={}.toString.call(e).slice(8,-1);return r==="Object"&&e.constructor&&(r=e.constructor.name),r==="Map"||r==="Set"?Array.from(e):r==="Arguments"||/^(?:Ui|I)nt(?:8|16|32)(?:Clamped)?Array$/.test(r)?gv(e,t):void 0}}function Xe(e){return function(t){t instanceof RegExp&&(t.lastIndex=0);for(var r=arguments.length,n=new Array(r>1?r-1:0),o=1;o<r;o++)n[o-1]=arguments[o];return lh(e,t,n)}}function O8(e){return function(){for(var t=arguments.length,r=new Array(t),n=0;n<t;n++)r[n]=arguments[n];return uh(e,r)}}function te(e,t){let r=arguments.length>2&&arguments[2]!==void 0?arguments[2]:Mc;if(hv&&hv(e,null),!po(t))return e;let n=t.length;for(;n--;){let o=t[n];if(typeof o=="string"){let i=r(o);i!==o&&(_8(t)||(t[n]=i),o=i)}e[o]=!0}return e}function G8(e){for(let t=0;t<e.length;t++)lt(e,t)||(e[t]=null);return e}function Lt(e){let t=Ja(null);for(let n of _v(e)){var r=Q8(n,2);let o=r[0],i=r[1];lt(e,o)&&(po(i)?t[o]=G8(i):i&&typeof i=="object"&&i.constructor===Object?t[o]=Lt(i):t[o]=i)}return t}function U8(e){switch(typeof e){case"string":return e;case"number":return F8(e);case"boolean":return P8(e);case"bigint":return Ev?Ev(e):"0";case"symbol":return bv?bv(e):"Symbol()";case"undefined":return Qc(e);case"function":case"object":{if(e===null)return Qc(e);let t=e,r=mn(t,"toString");if(typeof r=="function"){let n=r(t);return typeof n=="string"?n:Qc(n)}return Qc(e)}default:return Qc(e)}}function mn(e,t){for(;e!==null;){let n=D8(e,t);if(n){if(n.get)return Xe(n.get);if(typeof n.value=="function")return Xe(n.value)}e=k8(e)}function r(){return null}return r}function H8(e){try{return ct(e,""),!0}catch{return!1}}function Dv(){let e=arguments.length>0&&arguments[0]!==void 0?arguments[0]:r6(),t=F=>Dv(F);if(t.version="3.4.12",t.removed=[],!e||!e.document||e.document.nodeType!==rr.document||!e.Element)return t.isSupported=!1,t;let r=e.document,n=r,o=n.currentScript;e.DocumentFragment;let i=e.HTMLTemplateElement,a=e.Node,s=e.Element,c=e.NodeFilter,l=e.NamedNodeMap;l===void 0&&(e.NamedNodeMap||e.MozNamedAttrMap),e.HTMLFormElement;let u=e.DOMParser,A=e.trustedTypes,m=s.prototype,f=mn(m,"cloneNode"),g=mn(m,"remove"),y=mn(m,"nextSibling"),E=mn(m,"childNodes"),b=mn(m,"parentNode"),x=mn(m,"shadowRoot"),B=mn(m,"attributes"),I=a&&a.prototype?mn(a.prototype,"nodeType"):null,w=a&&a.prototype?mn(a.prototype,"nodeName"):null;if(typeof i=="function"){let F=r.createElement("template");F.content&&F.content.ownerDocument&&(r=F.content.ownerDocument)}let S,v="",D,N=!1,L=0,P=function(){if(L>0)throw Ai('A configured TRUSTED_TYPES_POLICY callback (createHTML or createScriptURL) must not call DOMPurify.sanitize, as that causes infinite recursion. Do not pass a policy whose callbacks wrap DOMPurify as TRUSTED_TYPES_POLICY; see the "DOMPurify and Trusted Types" section of the README.')},h=function(C){P(),L++;try{return S.createHTML(C)}finally{L--}},Q=function(C){P(),L++;try{return S.createScriptURL(C)}finally{L--}},_=function(){return N||(D=n6(A,o),N=!0),D},G=r,q=G.implementation,oe=G.createNodeIterator,tt=G.createDocumentFragment,_i=G.getElementsByTagName,lr=n.importNode,ue=Mv();t.isSupported=typeof _v=="function"&&typeof b=="function"&&q&&q.createHTMLDocument!==void 0;let Mr=Y8,ur=$8,Xr=q8,vn=J8,ki=W8,Tn=z8,zn=K8,ad=Z8,hs=vv,Ie=null,al=te({},[...Iv,...ih,...ah,...sh,...wv]),_e=null,Kn=te({},[...Sv,...ch,...Bv,...If]),we=Object.seal(Ja(null,{tagNameCheck:{writable:!0,configurable:!1,enumerable:!0,value:null},attributeNameCheck:{writable:!0,configurable:!1,enumerable:!0,value:null},allowCustomizedBuiltInElements:{writable:!0,configurable:!1,enumerable:!0,value:!1}})),Di=null,fe=null,ie=Object.seal(Ja(null,{tagCheck:{writable:!0,configurable:!1,enumerable:!0,value:null},attributeCheck:{writable:!0,configurable:!1,enumerable:!0,value:null}})),ke=!0,Se=!0,Jt=!1,Qt=!0,ge=!1,Je=!0,Wt=!1,Qn=!1,Ni=null,Ri=null,yt=!1,xt=!1,Xn=!1,Li=!1,Fi=!0,wC=!1,SC="user-content-",sd=!0,cd=!1,Pi={},Zr=null,ld=te({},["annotation-xml","audio","colgroup","desc","foreignobject","head","iframe","math","mi","mn","mo","ms","mtext","noembed","noframes","noscript","plaintext","script","selectedcontent","style","svg","template","thead","title","video","xmp"]),BC=null,vC=te({},["audio","video","img","source","image","track"]),ud=null,TC=te({},["alt","class","for","id","label","name","pattern","placeholder","role","summary","title","value","style","xmlns"]),sl="http://www.w3.org/1998/Math/MathML",cl="http://www.w3.org/2000/svg",en="http://www.w3.org/1999/xhtml",Oi=en,fd=!1,Ad=null,wL=te({},[sl,cl,en],oh),QC=mt(["mi","mo","mn","ms","mtext"]),dd=te({},QC),MC=mt(["annotation-xml"]),md=te({},MC),SL=te({},["title","style","font","a","script"]),Cs=null,BL=["application/xhtml+xml","text/html"],vL="text/html",Le=null,Gi=null,TL=r.createElement("form"),_C=function(C){return C instanceof RegExp||C instanceof Function},pd=function(){let C=arguments.length>0&&arguments[0]!==void 0?arguments[0]:{};if(Gi&&Gi===C)return;(!C||typeof C!="object")&&(C={}),C=Lt(C),Cs=BL.indexOf(C.PARSER_MEDIA_TYPE)===-1?vL:C.PARSER_MEDIA_TYPE,Le=Cs==="application/xhtml+xml"?oh:Mc,Ie=mo(C,"ALLOWED_TAGS",al,{transform:Le}),_e=mo(C,"ALLOWED_ATTR",Kn,{transform:Le}),Ad=mo(C,"ALLOWED_NAMESPACES",wL,{transform:oh}),ud=mo(C,"ADD_URI_SAFE_ATTR",TC,{transform:Le,base:TC}),BC=mo(C,"ADD_DATA_URI_TAGS",vC,{transform:Le,base:vC}),Zr=mo(C,"FORBID_CONTENTS",ld,{transform:Le}),Di=mo(C,"FORBID_TAGS",Lt({}),{transform:Le}),fe=mo(C,"FORBID_ATTR",Lt({}),{transform:Le}),Pi=lt(C,"USE_PROFILES")?C.USE_PROFILES&&typeof C.USE_PROFILES=="object"?Lt(C.USE_PROFILES):C.USE_PROFILES:!1,ke=C.ALLOW_ARIA_ATTR!==!1,Se=C.ALLOW_DATA_ATTR!==!1,Jt=C.ALLOW_UNKNOWN_PROTOCOLS||!1,Qt=C.ALLOW_SELF_CLOSE_IN_ATTR!==!1,ge=C.SAFE_FOR_TEMPLATES||!1,Je=C.SAFE_FOR_XML!==!1,Wt=C.WHOLE_DOCUMENT||!1,xt=C.RETURN_DOM||!1,Xn=C.RETURN_DOM_FRAGMENT||!1,Li=C.RETURN_TRUSTED_TYPE||!1,yt=C.FORCE_BODY||!1,Fi=C.SANITIZE_DOM!==!1,wC=C.SANITIZE_NAMED_PROPS||!1,sd=C.KEEP_CONTENT!==!1,cd=C.IN_PLACE||!1,hs=H8(C.ALLOWED_URI_REGEXP)?C.ALLOWED_URI_REGEXP:vv,Oi=typeof C.NAMESPACE=="string"?C.NAMESPACE:en,dd=lt(C,"MATHML_TEXT_INTEGRATION_POINTS")&&C.MATHML_TEXT_INTEGRATION_POINTS&&typeof C.MATHML_TEXT_INTEGRATION_POINTS=="object"?Lt(C.MATHML_TEXT_INTEGRATION_POINTS):te({},QC),md=lt(C,"HTML_INTEGRATION_POINTS")&&C.HTML_INTEGRATION_POINTS&&typeof C.HTML_INTEGRATION_POINTS=="object"?Lt(C.HTML_INTEGRATION_POINTS):te({},MC);let T=lt(C,"CUSTOM_ELEMENT_HANDLING")&&C.CUSTOM_ELEMENT_HANDLING&&typeof C.CUSTOM_ELEMENT_HANDLING=="object"?Lt(C.CUSTOM_ELEMENT_HANDLING):Ja(null);if(we=Ja(null),lt(T,"tagNameCheck")&&_C(T.tagNameCheck)&&(we.tagNameCheck=T.tagNameCheck),lt(T,"attributeNameCheck")&&_C(T.attributeNameCheck)&&(we.attributeNameCheck=T.attributeNameCheck),lt(T,"allowCustomizedBuiltInElements")&&typeof T.allowCustomizedBuiltInElements=="boolean"&&(we.allowCustomizedBuiltInElements=T.allowCustomizedBuiltInElements),pt(we),ge&&(Se=!1),Xn&&(xt=!0),Pi&&(Ie=te({},wv),_e=Ja(null),Pi.html===!0&&(te(Ie,Iv),te(_e,Sv)),Pi.svg===!0&&(te(Ie,ih),te(_e,ch),te(_e,If)),Pi.svgFilters===!0&&(te(Ie,ah),te(_e,ch),te(_e,If)),Pi.mathMl===!0&&(te(Ie,sh),te(_e,Bv),te(_e,If))),ie.tagCheck=null,ie.attributeCheck=null,lt(C,"ADD_TAGS")&&(typeof C.ADD_TAGS=="function"?ie.tagCheck=C.ADD_TAGS:po(C.ADD_TAGS)&&(Ie===al&&(Ie=Lt(Ie)),te(Ie,C.ADD_TAGS,Le))),lt(C,"ADD_ATTR")&&(typeof C.ADD_ATTR=="function"?ie.attributeCheck=C.ADD_ATTR:po(C.ADD_ATTR)&&(_e===Kn&&(_e=Lt(_e)),te(_e,C.ADD_ATTR,Le))),lt(C,"ADD_URI_SAFE_ATTR")&&po(C.ADD_URI_SAFE_ATTR)&&te(ud,C.ADD_URI_SAFE_ATTR,Le),lt(C,"FORBID_CONTENTS")&&po(C.FORBID_CONTENTS)&&(Zr===ld&&(Zr=Lt(Zr)),te(Zr,C.FORBID_CONTENTS,Le)),lt(C,"ADD_FORBID_CONTENTS")&&po(C.ADD_FORBID_CONTENTS)&&(Zr===ld&&(Zr=Lt(Zr)),te(Zr,C.ADD_FORBID_CONTENTS,Le)),sd&&(Ie["#text"]=!0),Wt&&te(Ie,["html","head","body"]),Ie.table&&(te(Ie,["tbody"]),delete Di.tbody),C.TRUSTED_TYPES_POLICY){if(typeof C.TRUSTED_TYPES_POLICY.createHTML!="function")throw Ai('TRUSTED_TYPES_POLICY configuration option must provide a "createHTML" hook.');if(typeof C.TRUSTED_TYPES_POLICY.createScriptURL!="function")throw Ai('TRUSTED_TYPES_POLICY configuration option must provide a "createScriptURL" hook.');let R=S;S=C.TRUSTED_TYPES_POLICY;try{v=h("")}catch(H){throw S=R,H}}else C.TRUSTED_TYPES_POLICY===null?(S=void 0,v=""):(S===void 0&&(S=_()),S&&typeof v=="string"&&(v=h("")));mt&&mt(C),Gi=C},kC=te({},[...ih,...ah,...V8]),DC=te({},[...sh,...j8]),QL=function(C,T,R){return T.namespaceURI===en?C==="svg":T.namespaceURI===sl?C==="svg"&&(R==="annotation-xml"||dd[R]):!!kC[C]},ML=function(C,T,R){return T.namespaceURI===en?C==="math":T.namespaceURI===cl?C==="math"&&md[R]:!!DC[C]},_L=function(C,T,R){return T.namespaceURI===cl&&!md[R]||T.namespaceURI===sl&&!dd[R]?!1:!DC[C]&&(SL[C]||!kC[C])},kL=function(C){let T=b(C);(!T||!T.tagName)&&(T={namespaceURI:Oi,tagName:"template"});let R=Mc(C.tagName),H=Mc(T.tagName);return Ad[C.namespaceURI]?C.namespaceURI===cl?QL(R,T,H):C.namespaceURI===sl?ML(R,T,H):C.namespaceURI===en?_L(R,T,H):!!(Cs==="application/xhtml+xml"&&Ad[C.namespaceURI]):!1},Zn=function(C){qa(t.removed,{element:C});try{b(C).removeChild(C)}catch{if(g(C),!b(C))throw Ai("a node selected for removal could not be detached from its tree and cannot be safely returned; refusing to sanitize in place")}},ll=function(C){gd(C);let T=E(C);if(T){let H=[];$a(T,J=>{qa(H,J)}),$a(H,J=>{try{g(J)}catch{}})}let R=B(C);if(R)for(let H=R.length-1;H>=0;--H){let J=R[H],W=J&&J.name;if(typeof W=="string")try{C.removeAttribute(W)}catch{}}},Lo=function(C,T){try{qa(t.removed,{attribute:T.getAttributeNode(C),from:T})}catch{qa(t.removed,{attribute:null,from:T})}if(T.removeAttribute(C),C==="is")if(xt||Xn)try{Zn(T)}catch{}else try{T.setAttribute(C,"")}catch{}},DL=function(C){let T=B(C);if(T)for(let R=T.length-1;R>=0;--R){let H=T[R],J=H&&H.name;if(!(typeof J!="string"||_e[Le(J)]))try{C.removeAttribute(J)}catch{}}},gd=function(C){let T=[C];for(;T.length>0;){let R=T.pop();(I?I(R):R.nodeType)===rr.element&&DL(R);let J=E(R);if(J)for(let W=J.length-1;W>=0;--W)T.push(J[W])}},NL=function(C){if(!Je)return;let T=[C];for(;T.length>0;){let R=T.pop(),H=I?I(R):R.nodeType;if(H===rr.processingInstruction||H===rr.comment&&ct(Qv,R.data)){try{g(R)}catch{}continue}if(H===rr.element){let W=R,Ge=Le(w?w(R):R.nodeName);try{W.hasAttribute&&W.hasAttribute("patchsrc")&&W.removeAttribute("patchsrc"),W.hasAttribute&&W.hasAttribute("for")&&Ge!=="label"&&Ge!=="output"&&W.removeAttribute("for")}catch{}}let J=E(R);if(J)for(let W=J.length-1;W>=0;--W)T.push(J[W])}},NC=function(C){let T=null,R=null;if(yt)C="<remove></remove>"+C;else{let W=yv(C,/^[\r\n\t ]+/);R=W&&W[0]}Cs==="application/xhtml+xml"&&Oi===en&&(C='<html xmlns="http://www.w3.org/1999/xhtml"><head></head><body>'+C+"</body></html>");let H=S?h(C):C;if(Oi===en)try{T=new u().parseFromString(H,Cs)}catch{}if(!T||!T.documentElement){T=q.createDocument(Oi,"template",null);try{T.documentElement.innerHTML=fd?v:H}catch{}}let J=T.body||T.documentElement;return C&&R&&J.insertBefore(r.createTextNode(R),J.childNodes[0]||null),Oi===en?_i.call(T,Wt?"html":"body")[0]:Wt?T.documentElement:J},RC=function(C){return oe.call(C.ownerDocument||C,C,c.SHOW_ELEMENT|c.SHOW_COMMENT|c.SHOW_TEXT|c.SHOW_PROCESSING_INSTRUCTION|c.SHOW_CDATA_SECTION,null)},ul=function(C){return C=Tc(C,Mr," "),C=Tc(C,ur," "),C=Tc(C,Xr," "),C},hd=function(C){var T;C.normalize();let R=oe.call(C.ownerDocument||C,C,c.SHOW_TEXT|c.SHOW_COMMENT|c.SHOW_CDATA_SECTION|c.SHOW_PROCESSING_INSTRUCTION,null),H=R.nextNode();for(;H;)H.data=ul(H.data),H=R.nextNode();let J=(T=C.querySelectorAll)===null||T===void 0?void 0:T.call(C,"template");J&&$a(J,W=>{Ui(W.content)&&hd(W.content)})},fl=function(C){let T=w?w(C):null;return typeof T!="string"||Le(T)!=="form"?!1:typeof C.nodeName!="string"||typeof C.textContent!="string"||typeof C.removeChild!="function"||C.attributes!==B(C)||typeof C.removeAttribute!="function"||typeof C.setAttribute!="function"||typeof C.namespaceURI!="string"||typeof C.insertBefore!="function"||typeof C.hasChildNodes!="function"||C.nodeType!==I(C)||C.childNodes!==E(C)},Ui=function(C){if(!I||typeof C!="object"||C===null)return!1;try{return I(C)===rr.documentFragment}catch{return!1}},ys=function(C){if(!I||typeof C!="object"||C===null)return!1;try{return typeof I(C)=="number"}catch{return!1}};function tn(F,C,T){F.length!==0&&$a(F,R=>{R.call(t,C,T,Gi)})}let RL=function(C,T){return!!(Je&&C.hasChildNodes()&&!ys(C.firstElementChild)&&ct(Tv,C.textContent)&&ct(Tv,C.innerHTML)||Je&&C.namespaceURI===en&&T==="style"&&ys(C.firstElementChild)||C.nodeType===rr.processingInstruction||Je&&C.nodeType===rr.comment&&ct(Qv,C.data))},LL=function(C,T){if(!Di[T]&&PC(T)&&(we.tagNameCheck instanceof RegExp&&ct(we.tagNameCheck,T)||we.tagNameCheck instanceof Function&&we.tagNameCheck(T)))return!1;if(sd&&!Zr[T]){let R=b(C),H=E(C);if(H&&R){let J=H.length;for(let W=J-1;W>=0;--W){let Ge=cd?H[W]:f(H[W],!0);R.insertBefore(Ge,y(C))}}}return Zn(C),!0},LC=function(C,T){if(tn(ue.beforeSanitizeElements,C,null),C!==T&&b(C)===null)return!0;if(fl(C))return Zn(C),!0;let R=Le(w?w(C):C.nodeName);if(tn(ue.uponSanitizeElement,C,{tagName:R,allowedTags:Ie}),C!==T&&b(C)===null)return!0;if(RL(C,R))return Zn(C),!0;if(Di[R]||!(ie.tagCheck instanceof Function&&ie.tagCheck(R))&&!Ie[R]){let J=LL(C,R);return J===!1&&tn(ue.afterSanitizeElements,C,null),J}if((I?I(C):C.nodeType)===rr.element&&!kL(C)||(R==="noscript"||R==="noembed"||R==="noframes")&&ct(e6,C.innerHTML))return Zn(C),!0;if(ge&&C.nodeType===rr.text){let J=ul(C.textContent);C.textContent!==J&&(qa(t.removed,{element:C.cloneNode()}),C.textContent=J)}return tn(ue.afterSanitizeElements,C,null),!1},FC=function(C,T,R){if(fe[T]||Je&&T==="patchsrc"||Je&&T==="for"&&C!=="label"&&C!=="output"||Fi&&(T==="id"||T==="name")&&(R in r||R in TL))return!1;let H=_e[T]||ie.attributeCheck instanceof Function&&ie.attributeCheck(T,C);if(!(Se&&ct(vn,T))){if(!(ke&&ct(ki,T))){if(H){if(!ud[T]){if(!ct(hs,Tc(R,zn,""))){if(!((T==="src"||T==="xlink:href"||T==="href")&&C!=="script"&&xv(R,"data:")===0&&BC[C])){if(!(Jt&&!ct(Tn,Tc(R,zn,"")))){if(R)return!1}}}}}else if(!(PC(C)&&(we.tagNameCheck instanceof RegExp&&ct(we.tagNameCheck,C)||we.tagNameCheck instanceof Function&&we.tagNameCheck(C))&&(we.attributeNameCheck instanceof RegExp&&ct(we.attributeNameCheck,T)||we.attributeNameCheck instanceof Function&&we.attributeNameCheck(T,C))||T==="is"&&we.allowCustomizedBuiltInElements&&(we.tagNameCheck instanceof RegExp&&ct(we.tagNameCheck,R)||we.tagNameCheck instanceof Function&&we.tagNameCheck(R))))return!1}}return!0},FL=te({},["annotation-xml","color-profile","font-face","font-face-format","font-face-name","font-face-src","font-face-uri","missing-glyph"]),PC=function(C){return!FL[Mc(C)]&&ct(ad,C)},PL=function(C,T,R,H){if(S&&typeof A=="object"&&typeof A.getAttributeType=="function"&&!R)switch(A.getAttributeType(C,T)){case"TrustedHTML":return h(H);case"TrustedScriptURL":return Q(H)}return H},OL=function(C,T,R,H){try{R?C.setAttributeNS(R,T,H):C.setAttribute(T,H),fl(C)?Zn(C):Cv(t.removed)}catch{Lo(T,C)}},OC=function(C){tn(ue.beforeSanitizeAttributes,C,null);let T=C.attributes;if(!T||fl(C))return;let R={attrName:"",attrValue:"",keepAttr:!0,allowedAttributes:_e,forceKeepAttr:void 0},H=T.length,J=Le(C.nodeName);for(;H--;){let W=T[H],Ge=W.name,Et=W.namespaceURI,_r=W.value,Ht=Le(Ge),kr=_r,Mt=Ge==="value"?kr:L8(kr);if(R.attrName=Ht,R.attrValue=Mt,R.keepAttr=!0,R.forceKeepAttr=void 0,tn(ue.uponSanitizeAttribute,C,R),Mt=R.attrValue,wC&&(Ht==="id"||Ht==="name")&&xv(Mt,SC)!==0&&(Lo(Ge,C),Mt=SC+Mt),Je&&ct(/((--!?|])>)|<\/(style|script|title|xmp|textarea|noscript|iframe|noembed|noframes)/i,Mt)){Lo(Ge,C);continue}if(Ht==="attributename"&&yv(Mt,"href")){Lo(Ge,C);continue}if(!R.forceKeepAttr){if(!R.keepAttr){Lo(Ge,C);continue}if(!Qt&&ct(t6,Mt)){Lo(Ge,C);continue}if(ge&&(Mt=ul(Mt)),!FC(J,Ht,Mt)){Lo(Ge,C);continue}Mt=PL(J,Ht,Et,Mt),Mt!==kr&&OL(C,Ge,Et,Mt)}}tn(ue.afterSanitizeAttributes,C,null)},Al=function(C){let T=null,R=RC(C);for(tn(ue.beforeSanitizeShadowDOM,C,null);T=R.nextNode();)if(tn(ue.uponSanitizeShadowNode,T,null),LC(T,C),OC(T),Ui(T.content)&&Al(T.content),(I?I(T):T.nodeType)===rr.element){let J=x(T);Ui(J)&&(Cd(J),Al(J))}tn(ue.afterSanitizeShadowDOM,C,null)},Cd=function(C){let T=[{node:C,shadow:null}];for(;T.length>0;){let R=T.pop();if(R.shadow){Al(R.shadow);continue}let H=R.node,W=(I?I(H):H.nodeType)===rr.element,Ge=E(H);if(Ge)for(let Et=Ge.length-1;Et>=0;--Et)T.push({node:Ge[Et],shadow:null});if(W){let Et=w?w(H):null;if(typeof Et=="string"&&Le(Et)==="template"){let _r=H.content;Ui(_r)&&T.push({node:_r,shadow:null})}}if(W){let Et=x(H);Ui(Et)&&T.push({node:null,shadow:Et},{node:Et,shadow:null})}}};return t.sanitize=function(F){let C=arguments.length>1&&arguments[1]!==void 0?arguments[1]:{},T=null,R=null,H=null,J=null;if(fd=!F,fd&&(F="<!-->"),typeof F!="string"&&!ys(F)&&(F=U8(F),typeof F!="string"))throw Ai("dirty is not a string, aborting");if(!t.isSupported)return F;Qn?(Ie=Ni,_e=Ri):pd(C),(ue.uponSanitizeElement.length>0||ue.uponSanitizeAttribute.length>0)&&(Ie=Lt(Ie)),ue.uponSanitizeAttribute.length>0&&(_e=Lt(_e)),t.removed=[];let W=cd&&typeof F!="string"&&ys(F);if(W){NL(F);let Ht=w?w(F):F.nodeName;if(typeof Ht=="string"){let kr=Le(Ht);if(!Ie[kr]||Di[kr])throw ll(F),Ai("root node is forbidden and cannot be sanitized in-place")}if(fl(F))throw ll(F),Ai("root node is clobbered and cannot be sanitized in-place");try{Cd(F)}catch(kr){throw ll(F),kr}}else if(ys(F))T=NC("<!---->"),R=T.ownerDocument.importNode(F,!0),R.nodeType===rr.element&&R.nodeName==="BODY"||R.nodeName==="HTML"?T=R:T.appendChild(R),Cd(R);else{if(!xt&&!ge&&!Wt&&F.indexOf("<")===-1)return S&&Li?h(F):F;if(T=NC(F),!T)return xt?null:Li?v:""}T&&yt&&Zn(T.firstChild);let Ge=W?F:T,Et=RC(Ge);try{for(;H=Et.nextNode();)LC(H,Ge),OC(H),Ui(H.content)&&Al(H.content)}catch(Ht){throw W&&(ll(F),$a(t.removed,kr=>{kr.element&&gd(kr.element)})),Ht}if(W)return $a(t.removed,Ht=>{Ht.element&&gd(Ht.element)}),ge&&hd(F),F;if(xt){if(ge&&hd(T),Xn)for(J=tt.call(T.ownerDocument);T.firstChild;)J.appendChild(T.firstChild);else J=T;return(_e.shadowroot||_e.shadowrootmode)&&(J=lr.call(n,J,!0)),J}let _r=Wt?T.outerHTML:T.innerHTML;return Wt&&Ie["!doctype"]&&T.ownerDocument&&T.ownerDocument.doctype&&T.ownerDocument.doctype.name&&ct(X8,T.ownerDocument.doctype.name)&&(_r="<!DOCTYPE "+T.ownerDocument.doctype.name+`>
+`+_r),ge&&(_r=ul(_r)),S&&Li?h(_r):_r},t.setConfig=function(){let F=arguments.length>0&&arguments[0]!==void 0?arguments[0]:{};pd(F),Qn=!0,Ni=Ie,Ri=_e},t.clearConfig=function(){Gi=null,Qn=!1,Ni=null,Ri=null,S=D,v=""},t.isValidAttribute=function(F,C,T){Gi||pd({});let R=Le(F),H=Le(C);return FC(R,H,T)},t.addHook=function(F,C){typeof C=="function"&&lt(ue,F)&&qa(ue[F],C)},t.removeHook=function(F,C){if(lt(ue,F)){if(C!==void 0){let T=N8(ue[F],C);return T===-1?void 0:R8(ue[F],T,1)[0]}return Cv(ue[F])}},t.removeHooks=function(F){lt(ue,F)&&(ue[F]=[])},t.removeAllHooks=function(){ue=Mv()},t}var _v,hv,_8,k8,D8,mt,pt,Ja,kv,lh,uh,$a,N8,Cv,qa,R8,po,Mc,oh,yv,Tc,xv,L8,F8,P8,Ev,bv,lt,Qc,ct,Ai,Iv,ih,ah,V8,sh,j8,wv,Sv,ch,Bv,If,Y8,$8,q8,J8,W8,vv,z8,K8,X8,Z8,Tv,Qv,e6,t6,rr,r6,n6,Mv,mo,Nv,Rv=d(()=>{_v=Object.entries,hv=Object.setPrototypeOf,_8=Object.isFrozen,k8=Object.getPrototypeOf,D8=Object.getOwnPropertyDescriptor,mt=Object.freeze,pt=Object.seal,Ja=Object.create,kv=typeof Reflect<"u"&&Reflect,lh=kv.apply,uh=kv.construct;mt||(mt=function(t){return t});pt||(pt=function(t){return t});lh||(lh=function(t,r){for(var n=arguments.length,o=new Array(n>2?n-2:0),i=2;i<n;i++)o[i-2]=arguments[i];return t.apply(r,o)});uh||(uh=function(t){for(var r=arguments.length,n=new Array(r>1?r-1:0),o=1;o<r;o++)n[o-1]=arguments[o];return new t(...n)});$a=Xe(Array.prototype.forEach),N8=Xe(Array.prototype.lastIndexOf),Cv=Xe(Array.prototype.pop),qa=Xe(Array.prototype.push),R8=Xe(Array.prototype.splice),po=Array.isArray,Mc=Xe(String.prototype.toLowerCase),oh=Xe(String.prototype.toString),yv=Xe(String.prototype.match),Tc=Xe(String.prototype.replace),xv=Xe(String.prototype.indexOf),L8=Xe(String.prototype.trim),F8=Xe(Number.prototype.toString),P8=Xe(Boolean.prototype.toString),Ev=typeof BigInt>"u"?null:Xe(BigInt.prototype.toString),bv=typeof Symbol>"u"?null:Xe(Symbol.prototype.toString),lt=Xe(Object.prototype.hasOwnProperty),Qc=Xe(Object.prototype.toString),ct=Xe(RegExp.prototype.test),Ai=O8(TypeError);Iv=mt(["a","abbr","acronym","address","area","article","aside","audio","b","bdi","bdo","big","blink","blockquote","body","br","button","canvas","caption","center","cite","code","col","colgroup","content","data","datalist","dd","decorator","del","details","dfn","dialog","dir","div","dl","dt","element","em","fieldset","figcaption","figure","font","footer","form","h1","h2","h3","h4","h5","h6","head","header","hgroup","hr","html","i","img","input","ins","kbd","label","legend","li","main","map","mark","marquee","menu","menuitem","meter","nav","nobr","ol","optgroup","option","output","p","picture","pre","progress","q","rp","rt","ruby","s","samp","search","section","select","shadow","slot","small","source","spacer","span","strike","strong","style","sub","summary","sup","table","tbody","td","template","textarea","tfoot","th","thead","time","tr","track","tt","u","ul","var","video","wbr"]),ih=mt(["svg","a","altglyph","altglyphdef","altglyphitem","animatecolor","animatemotion","animatetransform","circle","clippath","defs","desc","ellipse","enterkeyhint","exportparts","filter","font","g","glyph","glyphref","hkern","image","inputmode","line","lineargradient","marker","mask","metadata","mpath","part","path","pattern","polygon","polyline","radialgradient","rect","stop","style","switch","symbol","text","textpath","title","tref","tspan","view","vkern"]),ah=mt(["feBlend","feColorMatrix","feComponentTransfer","feComposite","feConvolveMatrix","feDiffuseLighting","feDisplacementMap","feDistantLight","feDropShadow","feFlood","feFuncA","feFuncB","feFuncG","feFuncR","feGaussianBlur","feImage","feMerge","feMergeNode","feMorphology","feOffset","fePointLight","feSpecularLighting","feSpotLight","feTile","feTurbulence"]),V8=mt(["animate","color-profile","cursor","discard","font-face","font-face-format","font-face-name","font-face-src","font-face-uri","foreignobject","hatch","hatchpath","mesh","meshgradient","meshpatch","meshrow","missing-glyph","script","set","solidcolor","unknown","use"]),sh=mt(["math","menclose","merror","mfenced","mfrac","mglyph","mi","mlabeledtr","mmultiscripts","mn","mo","mover","mpadded","mphantom","mroot","mrow","ms","mspace","msqrt","mstyle","msub","msup","msubsup","mtable","mtd","mtext","mtr","munder","munderover","mprescripts"]),j8=mt(["maction","maligngroup","malignmark","mlongdiv","mscarries","mscarry","msgroup","mstack","msline","msrow","semantics","annotation","annotation-xml","mprescripts","none"]),wv=mt(["#text"]),Sv=mt(["accept","action","align","alt","autocapitalize","autocomplete","autopictureinpicture","autoplay","background","bgcolor","border","capture","cellpadding","cellspacing","checked","cite","class","clear","color","cols","colspan","command","commandfor","controls","controlslist","coords","crossorigin","datetime","decoding","default","dir","disabled","disablepictureinpicture","disableremoteplayback","download","draggable","enctype","enterkeyhint","exportparts","face","for","headers","height","hidden","high","href","hreflang","id","inert","inputmode","integrity","ismap","kind","label","lang","list","loading","loop","low","max","maxlength","media","method","min","minlength","multiple","muted","name","nonce","noshade","novalidate","nowrap","open","optimum","part","pattern","placeholder","playsinline","popover","popovertarget","popovertargetaction","poster","preload","pubdate","radiogroup","readonly","rel","required","rev","reversed","role","rows","rowspan","spellcheck","scope","selected","shape","size","sizes","slot","span","srclang","start","src","srcset","step","style","summary","tabindex","title","translate","type","usemap","valign","value","width","wrap","xmlns"]),ch=mt(["accent-height","accumulate","additive","alignment-baseline","amplitude","ascent","attributename","attributetype","azimuth","basefrequency","baseline-shift","begin","bias","by","class","clip","clippathunits","clip-path","clip-rule","color","color-interpolation","color-interpolation-filters","color-profile","color-rendering","cx","cy","d","dx","dy","diffuseconstant","direction","display","divisor","dominant-baseline","dur","edgemode","elevation","end","exponent","fill","fill-opacity","fill-rule","filter","filterunits","flood-color","flood-opacity","font-family","font-size","font-size-adjust","font-stretch","font-style","font-variant","font-weight","fx","fy","g1","g2","glyph-name","glyphref","gradientunits","gradienttransform","height","href","id","image-rendering","in","in2","intercept","k","k1","k2","k3","k4","kerning","keypoints","keysplines","keytimes","lang","lengthadjust","letter-spacing","kernelmatrix","kernelunitlength","lighting-color","local","marker-end","marker-mid","marker-start","markerheight","markerunits","markerwidth","maskcontentunits","maskunits","max","mask","mask-type","media","method","mode","min","name","numoctaves","offset","operator","opacity","order","orient","orientation","origin","overflow","paint-order","path","pathlength","patterncontentunits","patterntransform","patternunits","points","preservealpha","preserveaspectratio","primitiveunits","r","rx","ry","radius","refx","refy","repeatcount","repeatdur","restart","result","rotate","scale","seed","shape-rendering","slope","specularconstant","specularexponent","spreadmethod","startoffset","stddeviation","stitchtiles","stop-color","stop-opacity","stroke-dasharray","stroke-dashoffset","stroke-linecap","stroke-linejoin","stroke-miterlimit","stroke-opacity","stroke","stroke-width","style","surfacescale","systemlanguage","tabindex","tablevalues","targetx","targety","transform","transform-origin","text-anchor","text-decoration","text-orientation","text-rendering","textlength","type","u1","u2","unicode","values","viewbox","visibility","version","vert-adv-y","vert-origin-x","vert-origin-y","width","word-spacing","wrap","writing-mode","xchannelselector","ychannelselector","x","x1","x2","xmlns","y","y1","y2","z","zoomandpan"]),Bv=mt(["accent","accentunder","align","bevelled","close","columnalign","columnlines","columnspacing","columnspan","denomalign","depth","dir","display","displaystyle","encoding","fence","frame","height","href","id","largeop","length","linethickness","lquote","lspace","mathbackground","mathcolor","mathsize","mathvariant","maxsize","minsize","movablelimits","notation","numalign","open","rowalign","rowlines","rowspacing","rowspan","rspace","rquote","scriptlevel","scriptminsize","scriptsizemultiplier","selection","separator","separators","stretchy","subscriptshift","supscriptshift","symmetric","voffset","width","xmlns"]),If=mt(["xlink:href","xml:id","xlink:title","xml:space","xmlns:xlink"]),Y8=pt(/{{[\w\W]*|^[\w\W]*}}/g),$8=pt(/<%[\w\W]*|^[\w\W]*%>/g),q8=pt(/\${[\w\W]*/g),J8=pt(/^data-[\-\w.\u00B7-\uFFFF]+$/),W8=pt(/^aria-[\-\w]+$/),vv=pt(/^(?:(?:(?:f|ht)tps?|mailto|tel|callto|sms|cid|xmpp|matrix):|[^a-z]|[a-z+.\-]+(?:[^a-z+.\-:]|$))/i),z8=pt(/^(?:\w+script|data):/i),K8=pt(/[\u0000-\u0020\u00A0\u1680\u180E\u2000-\u2029\u205F\u3000]/g),X8=pt(/^html$/i),Z8=pt(/^[a-z][.\w]*(-[.\w]+)+$/i),Tv=pt(/<[/\w!]/g),Qv=pt(/<[/\w]/g),e6=pt(/<\/no(script|embed|frames)/i),t6=pt(/\/>/i),rr={element:1,attribute:2,text:3,cdataSection:4,entityReference:5,entityNode:6,processingInstruction:7,comment:8,document:9,documentType:10,documentFragment:11,notation:12},r6=function(){return typeof window>"u"?null:window},n6=function(t,r){if(typeof t!="object"||typeof t.createPolicy!="function")return null;let n=null,o="data-tt-policy-suffix";r&&r.hasAttribute(o)&&(n=r.getAttribute(o));let i="dompurify"+(n?"#"+n:"");try{return t.createPolicy(i,{createHTML(a){return a},createScriptURL(a){return a}})}catch{return console.warn("TrustedTypes policy "+i+" could not be created."),null}},Mv=function(){return{afterSanitizeAttributes:[],afterSanitizeElements:[],afterSanitizeShadowDOM:[],beforeSanitizeAttributes:[],beforeSanitizeElements:[],beforeSanitizeShadowDOM:[],uponSanitizeAttribute:[],uponSanitizeElement:[],uponSanitizeShadowNode:[]}},mo=function(t,r,n,o){return lt(t,r)&&po(t[r])?te(o.base?Lt(o.base):{},t[r],o.transform):n};Nv=Dv()});var Pv={};bt(Pv,{default:()=>Fv});function Fv({value:e,className:t}){let r=(0,wf.useRef)(null);return(0,wf.useLayoutEffect)(()=>{let n=r.current;if(n)for(let o of n.querySelectorAll("a"))o.setAttribute("rel","noopener noreferrer"),o.setAttribute("target","_blank")},[e]),(0,Lv.jsx)("span",{ref:r,className:t,dangerouslySetInnerHTML:{__html:Nv.sanitize(e)}})}var Lv,wf,Ov=d(()=>{Lv=p(O(),1),wf=p(k(),1);Rv()});function s6(e){return a6.test(e)}function c6(e){return e.includes("<")||e.includes("://")}function l6({value:e,className:t}){let r=(0,go.useRef)(null);return(0,go.useLayoutEffect)(()=>{let n=r.current;if(n)try{n.setHTML(e);for(let o of n.querySelectorAll("a"))o.setAttribute("rel","noopener noreferrer"),o.setAttribute("target","_blank")}catch(o){console.error(o)}},[e]),(0,di.jsx)("span",{ref:r,className:t})}function ho({html:e,className:t}){let r=`${e}`;if(!c6(r))return(0,di.jsx)("span",{className:t,children:r});let n=mv(r),o=s6(n)?n:(0,Gv.default)(n);return typeof Element<"u"&&Element.prototype.setHTML?(0,di.jsx)(l6,{value:o,className:t}):(0,di.jsx)(go.Suspense,{fallback:(0,di.jsx)("span",{className:t}),children:(0,di.jsx)(i6,{value:o,className:t})})}var di,go,Gv,o6,i6,a6,fh=d(()=>{di=p(O(),1),go=p(k(),1),Gv=p(GS(),1);Ao();o6=["a","b","br","code","div","em","h1","h2","h3","h4","h5","h6","i","img","li","mark","p","pre","span","small","strong","table","tbody","sup","sub","td","tfoot","th","thead","tr","u","ul"],i6=(0,go.lazy)(()=>Promise.resolve().then(()=>(Ov(),Pv))),a6=new RegExp(o6.map(e=>String.raw`<${e}\b[^>]*>`).join("|"),"i")});function u6({error:e}){let{classes:t}=Vv();return(0,nr.jsx)("div",{className:t.errorBox,children:(0,nr.jsx)(FS,{error:e})})}var nr,Uv,wt,Hv,Vv,f6,jv,Yv=d(()=>{nr=p(O(),1),Uv=p(k(),1);Rp();wt=p(V(),1),Hv=p($(),1);Sp();PS();fh();$e();Vv=X()(e=>({closeButton:{position:"absolute",right:e.spacing(1),top:e.spacing(1),color:e.palette.grey[500]},errorBox:{width:800,margin:40}}));f6=(0,Hv.observer)(function(t){let{classes:r}=Vv(),{titleNode:n,...o}=t,{title:i,header:a,children:s,onClose:c}=o,l=(0,wt.useTheme)();return(0,nr.jsx)(wt.Dialog,{...o,children:(0,nr.jsxs)(wt.ScopedCssBaseline,{children:[(0,Uv.isValidElement)(a)?a:(0,nr.jsxs)(wt.DialogTitle,{children:[n||(0,nr.jsx)(ho,{html:i||""}),c?(0,nr.jsx)(wt.IconButton,{className:r.closeButton,onClick:u=>{c(u,"backdropClick")},children:(0,nr.jsx)(Uu,{})}):null]}),(0,nr.jsx)(wt.Divider,{}),(0,nr.jsx)(Ia,{FallbackComponent:u6,children:(0,nr.jsx)(wt.ThemeProvider,{theme:(0,wt.createTheme)(l,{components:{MuiInputBase:{styleOverrides:{input:{boxSizing:"content-box!important"}}}}}),children:s})})]})})}),jv=f6});function Ah({onClose:e,helpText:t,label:r}){return(0,mi.jsx)(jv,{open:!0,onClose:e,title:"Help",titleNode:r?(0,mi.jsxs)(mi.Fragment,{children:["Help: ",r]}):void 0,onClick:n=>{n.stopPropagation()},onMouseDown:n=>{n.stopPropagation()},children:(0,mi.jsx)($v.DialogContent,{children:t})})}var mi,$v,qv=d(()=>{mi=p(O(),1),$v=p(V(),1);Yv()});function dh({helpText:e,label:t}){let[r,n]=(0,Sf.useState)(!1);return(0,jn.jsxs)(jn.Fragment,{children:[(0,jn.jsx)(Jv.IconButton,{size:"small",onClick:o=>{o.stopPropagation(),n(!0)},style:{marginLeft:4,padding:4},children:(0,jn.jsx)(kw,{fontSize:"small"})}),r?(0,jn.jsxs)(Sf.Suspense,{fallback:null,children:[(0,jn.jsx)(Ah,{helpText:e,label:t,onClose:o=>{o.stopPropagation(),n(!1)}})," "]}):null]})}var jn,Sf,Jv,Wv=d(()=>{jn=p(O(),1),Sf=p(k(),1);Dw();Jv=p(V(),1);qv()});var zv,Kv,Xv,A6,Zv,eT=d(()=>{zv=p(O(),1),Kv=p(k(),1),Xv=p(V(),1),A6=Kv.forwardRef(function(t,r){return(0,zv.jsx)(Xv.Menu,{...t,ref:r,style:{pointerEvents:"none",...t.style},slotProps:{...t.slotProps,paper:{style:{pointerEvents:"auto"}}}})}),Zv=A6});var tT,rT,nT=d(()=>{"use client";Xt();tT=p(O(),1),rT=(0,ve.createSvgIcon)((0,tT.jsx)("path",{d:"m10 17 5-5-5-5z"}),"ArrowRight")});var oT,iT,aT=d(()=>{"use client";Xt();oT=p(O(),1),iT=(0,ve.createSvgIcon)((0,oT.jsx)("path",{d:"M19 3H5c-1.11 0-2 .9-2 2v14c0 1.1.89 2 2 2h14c1.11 0 2-.9 2-2V5c0-1.1-.89-2-2-2m-9 14-5-5 1.41-1.41L10 14.17l7.59-7.59L19 8z"}),"CheckBox")});var sT,cT,lT=d(()=>{"use client";Xt();sT=p(O(),1),cT=(0,ve.createSvgIcon)((0,sT.jsx)("path",{d:"M19 5v14H5V5zm0-2H5c-1.1 0-2 .9-2 2v14c0 1.1.9 2 2 2h14c1.1 0 2-.9 2-2V5c0-1.1-.9-2-2-2"}),"CheckBoxOutlineBlank")});var uT,fT,AT=d(()=>{"use client";Xt();uT=p(O(),1),fT=(0,ve.createSvgIcon)((0,uT.jsx)("path",{d:"M12 7c-2.76 0-5 2.24-5 5s2.24 5 5 5 5-2.24 5-5-2.24-5-5-5m0-5C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m0 18c-4.42 0-8-3.58-8-8s3.58-8 8-8 8 3.58 8 8-3.58 8-8 8"}),"RadioButtonChecked")});var dT,mT,pT=d(()=>{"use client";Xt();dT=p(O(),1),mT=(0,ve.createSvgIcon)((0,dT.jsx)("path",{d:"M12 2C6.48 2 2 6.48 2 12s4.48 10 10 10 10-4.48 10-10S17.52 2 12 2m0 18c-4.42 0-8-3.58-8-8s3.58-8 8-8 8 3.58 8 8-3.58 8-8 8"}),"RadioButtonUnchecked")});function gT(e){let{classes:t}=d6(),{type:r}=e,n,o;"checked"in e&&({checked:n,disabled:o}=e);let i;switch(r){case"subMenu":{i=(0,Co.jsx)(rT,{color:"action"});break}case"checkbox":{n?i=(0,Co.jsx)(iT,{color:o?"inherit":void 0}):i=(0,Co.jsx)(cT,{color:"action"});break}case"radio":{n?i=(0,Co.jsx)(fT,{color:o?"inherit":void 0}):i=(0,Co.jsx)(mT,{color:"action"});break}}return(0,Co.jsx)("div",{className:t.menuItemEndDecoration,children:i})}var Co,Bf,d6,hT=d(()=>{Co=p(O(),1);nT();aT();lT();AT();pT();Bf=p(V(),1);$e();d6=X()({menuItemEndDecoration:{padding:0,margin:0,height:16}})});function CT(e){if(typeof e=="string")return e.toLowerCase().replace(/\s+/g,"_")}function m6({title:e,Icon:t,inset:r,menuItems:n,onMenuItemClick:o,closeAfterItemClick:i,onCloseRoot:a,isOpen:s,onOpen:c,onClose:l}){let[u,A]=(0,mh.useState)(null),m=CT(e);return(0,ye.jsxs)(ye.Fragment,{children:[(0,ye.jsxs)(Ft.MenuItem,{ref:A,"data-testid":m?`cascading-submenu-${m}`:void 0,onMouseOver:c,onFocus:c,onClick:c,children:[t?(0,ye.jsx)(Ft.ListItemIcon,{children:(0,ye.jsx)(t,{})}):null,(0,ye.jsx)(Ft.ListItemText,{primary:e,inset:r}),(0,ye.jsx)(Qw,{})]}),(0,ye.jsx)(Zv,{open:s,anchorEl:u,onClose:l,anchorOrigin:{vertical:"top",horizontal:"right"},transformOrigin:{vertical:"top",horizontal:"left"},children:(0,ye.jsx)(yT,{closeAfterItemClick:i,onMenuItemClick:o,menuItems:n,onCloseRoot:a})})]})}function yT({onMenuItemClick:e,closeAfterItemClick:t,menuItems:r,onCloseRoot:n}){let[o,i]=(0,mh.useState)(),a=()=>{i(void 0)},s=r.some(u=>"icon"in u&&u.icon),c=r.some(u=>(u.type==="checkbox"||u.type==="radio")&&"helpText"in u&&u.helpText),l=r.toSorted((u,A)=>(A.priority||0)-(u.priority||0));return(0,ye.jsx)(ye.Fragment,{children:l.map((u,A)=>{if("subMenu"in u)return(0,ye.jsx)(m6,{title:u.label,Icon:u.icon,inset:s&&!u.icon,onMenuItemClick:e,menuItems:u.subMenu,closeAfterItemClick:t,onCloseRoot:n,isOpen:o===A,onOpen:()=>{i(A)},onClose:a},`subMenu-${u.label}-${A}`);if(u.type==="divider")return(0,ye.jsx)(Ft.Divider,{component:"li"},`divider-${A}`);if(u.type==="subHeader")return(0,ye.jsx)(Ft.ListSubheader,{children:u.label},`subHeader-${u.label}-${A}`);let m=u,f=m.helpText,g=m.type==="checkbox"||m.type==="radio",y=CT(m.label);return(0,ye.jsxs)(Ft.MenuItem,{"data-testid":y?`cascading-menuitem-${y}`:void 0,disabled:!!m.disabled,onClick:E=>{t&&n(),e(E,m.onClick)},onMouseOver:a,children:[m.icon?(0,ye.jsx)(Ft.ListItemIcon,{children:(0,ye.jsx)(m.icon,{})}):null,(0,ye.jsx)(Ft.ListItemText,{primary:m.label,secondary:m.subLabel,inset:s&&!m.icon}),(0,ye.jsx)("div",{style:{flexGrow:1,minWidth:10}}),g?(0,ye.jsx)(gT,{type:m.type,checked:m.checked,disabled:m.disabled}):null,f?(0,ye.jsx)(dh,{helpText:f,label:m.label}):g&&c?(0,ye.jsx)("div",{style:{marginLeft:4,padding:4,width:28,height:28}}):null]},`${m.label}-${A}`)})})}function ph({onMenuItemClick:e,closeAfterItemClick:t=!0,menuItems:r,open:n,onClose:o,anchorEl:i,anchorOrigin:a,transformOrigin:s,anchorReference:c,anchorPosition:l,slotProps:u,marginThreshold:A,style:m}){let f=Array.isArray(r)?r:r();return(0,ye.jsx)(Ft.Menu,{anchorEl:i,open:n,onClose:o,anchorOrigin:a,transformOrigin:s,anchorReference:c,anchorPosition:l,slotProps:u,marginThreshold:A??void 0,style:m,children:(0,ye.jsx)(yT,{menuItems:f,closeAfterItemClick:t,onMenuItemClick:e,onCloseRoot:o})})}var ye,mh,Ft,xT=d(()=>{ye=p(O(),1),mh=p(k(),1);Mw();Ft=p(V(),1);Wv();eT();hT()});function p6({children:e,menuItems:t,closeAfterItemClick:r=!0,stopPropagation:n,disabled:o,setOpen:i,ButtonComponent:a=ET.IconButton,onClick:s,anchorOrigin:c,transformOrigin:l,marginThreshold:u,...A}){let[m,f]=(0,vf.useState)(null),g=!!m;(0,vf.useEffect)(()=>{i?.(g)},[g,i]);let y=o??(Array.isArray(t)&&t.length===0);return(0,pi.jsxs)(pi.Fragment,{children:[(0,pi.jsx)(a,{onClick:E=>{n&&E.stopPropagation(),f(E.currentTarget),s?.(E)},...A,disabled:y,children:e}),g?(0,pi.jsx)(ph,{open:g,onClose:()=>{f(null)},anchorEl:m,anchorOrigin:c,transformOrigin:l,marginThreshold:u,menuItems:t,closeAfterItemClick:r,onMenuItemClick:(E,b)=>{b()}}):null]})}var pi,vf,ET,pn,Wa=d(()=>{pi=p(O(),1),vf=p(k(),1),ET=p(V(),1);xT();pn=p6});var bT,IT,wT=d(()=>{"use client";Ee();bT=p(O(),1),IT=Y((0,bT.jsx)("path",{d:"M12 2C6.49 2 2 6.49 2 12s4.49 10 10 10c1.38 0 2.5-1.12 2.5-2.5 0-.61-.23-1.2-.64-1.67-.08-.1-.13-.21-.13-.33 0-.28.22-.5.5-.5H16c3.31 0 6-2.69 6-6 0-4.96-4.49-9-10-9m5.5 11c-.83 0-1.5-.67-1.5-1.5s.67-1.5 1.5-1.5 1.5.67 1.5 1.5-.67 1.5-1.5 1.5m-3-4c-.83 0-1.5-.67-1.5-1.5S13.67 6 14.5 6s1.5.67 1.5 1.5S15.33 9 14.5 9M5 11.5c0-.83.67-1.5 1.5-1.5s1.5.67 1.5 1.5S7.33 13 6.5 13 5 12.33 5 11.5m6-4c0 .83-.67 1.5-1.5 1.5S8 8.33 8 7.5 8.67 6 9.5 6s1.5.67 1.5 1.5"}),"Palette")});var ST=d(()=>{vm();Qm();Mm();Tm()});var BT,g6,_c,gh=d(()=>{ST();rc();lp();so();Tu([Qu]);BT={A:cn[500],C:sn[500],G:Dn[500],T:Rr[500],U:Rr[500]},g6={none:{},nucleotide:BT,clustal:{G:"orange",P:"orange",S:"orange",T:"orange",H:"red",K:"red",R:"red",F:"blue",W:"blue",Y:"blue",I:"green",L:"green",M:"green",V:"green"},lesk:{G:"orange",A:"orange",S:"orange",T:"orange",C:"green",V:"green",I:"green",L:"green",P:"green",F:"green",Y:"green",M:"green",W:"green",N:"magenta",Q:"magenta",H:"magenta",D:"red",E:"red",K:"blue",R:"blue"},maeditor:{A:"lightgreen",G:"lightgreen",C:"green",D:"darkgreen",E:"darkgreen",N:"darkgreen",Q:"darkgreen",I:"blue",L:"blue",M:"blue",V:"blue",F:"#c8a2c8",W:"#c8a2c8",Y:"#c8a2c8",H:"darkblue",K:"orange",R:"orange",P:"pink",S:"red",T:"red"},percent_identity_dynamic:{},flower:{A:"#b18a51",C:"#ff5701",D:"#01a578",E:"#2da0a1",F:"#fa559d",G:"#b1c23c",H:"#0194f9",I:"#f27663",K:"#7fc3d7",L:"#df6e75",M:"#fe9daf",N:"#0bcec6",P:"#4fa32a",Q:"#7295ae",R:"#83bff1",S:"#b4bd9b",T:"#d2b576",V:"#fd997b",W:"#ff2ded",Y:"#c96ecf"},rainbow_dna:{A:"#3737f5",C:"#37f537",G:"#f5f537",T:"#f53737",U:"#f53737"},clustalx_protein:{A:"#197fe5",C:"#e57f7f",D:"#cc4ccc",E:"#cc4ccc",F:"#197fe5",G:"#e5994c",H:"#19b2b2",I:"#197fe5",K:"#e53319",L:"#197fe5",M:"#197fe5",N:"#19cc19",P:"#cccc00",Q:"#19cc19",R:"#e53319",S:"#19cc19",T:"#19cc19",V:"#197fe5",W:"#197fe5",Y:"#19b2b2"},clustalx_protein_dynamic:{},clustalx_dna:{A:"#e53319",C:"#197fe5",G:"#e5994c",T:"#19cc19",U:"#19cc19"},jbrowse_dna:BT,jalview_buried:{A:"#00a35c",R:"#00fc03",N:"#00eb14",D:"#00eb14",C:"#0000ff",Q:"#00f10e",E:"#00f10e",G:"#009d62",H:"#00d52a",I:"#0054ab",L:"#007b84",K:"#00ff00",M:"#009768",F:"#008778",P:"#00e01f",S:"#00d52a",T:"#00db24",W:"#00a857",Y:"#00e619",V:"#005fa0",B:"#00eb14",X:"#00b649",Z:"#00f10e"},jalview_hydrophobicity:{A:"#ad0052",R:"#0000ff",N:"#0c00f3",D:"#0c00f3",C:"#c2003d",Q:"#0c00f3",E:"#0c00f3",G:"#6a0095",H:"#1500ea",I:"#ff0000",L:"#ea0015",K:"#0000ff",M:"#b0004f",F:"#cb0034",P:"#4600b9",S:"#5e00a1",T:"#61009e",W:"#5b00a4",Y:"#4f00b0",V:"#f60009",B:"#0c00f3",X:"#680097",Z:"#0c00f3"},jalview_prophelix:{A:"#e718e7",R:"#6f906f",N:"#1be41b",D:"#778877",C:"#23dc23",Q:"#926d92",E:"#ff00ff",G:"#00ff00",H:"#758a75",I:"#8a758a",L:"#ae51ae",K:"#a05fa0",M:"#ef10ef",F:"#986798",P:"#00ff00",S:"#36c936",T:"#47b847",W:"#8a758a",Y:"#21de21",V:"#857a85",B:"#49b649",X:"#758a75",Z:"#c936c9"},jalview_propstrand:{A:"#5858a7",R:"#6b6b94",N:"#64649b",D:"#2121de",C:"#9d9d62",Q:"#8c8c73",E:"#0000ff",G:"#4949b6",H:"#60609f",I:"#ecec13",L:"#b2b24d",K:"#4747b8",M:"#82827d",F:"#c2c23d",P:"#2323dc",S:"#4949b6",T:"#9d9d62",W:"#c0c03f",Y:"#d3d32c",V:"#ffff00",B:"#4343bc",X:"#797986",Z:"#4747b8"},jalview_propturn:{A:"#2cd3d3",R:"#708f8f",N:"#ff0000",D:"#e81717",C:"#a85757",Q:"#3fc0c0",E:"#778888",G:"#ff0000",H:"#708f8f",I:"#00ffff",L:"#1ce3e3",K:"#7e8181",M:"#1ee1e1",F:"#1ee1e1",P:"#f60909",S:"#e11e1e",T:"#738c8c",W:"#738c8c",Y:"#9d6262",V:"#07f8f8",B:"#f30c0c",X:"#7c8383",Z:"#5ba4a4"},jalview_taylor:{A:"#ccff00",R:"#0000ff",N:"#cc00ff",D:"#ff0000",C:"#ffff00",Q:"#ff00cc",E:"#ff0066",G:"#ff9900",H:"#0066ff",I:"#66ff00",L:"#33ff00",K:"#6600ff",M:"#00ff00",F:"#00ff66",P:"#ffcc00",S:"#ff3300",T:"#ff6600",W:"#00ccff",Y:"#00ffcc",V:"#99ff00"},jalview_zappo:{A:"#ffafaf",R:"#6464ff",N:"#00ff00",D:"#ff0000",C:"#ffff00",Q:"#00ff00",E:"#ff0000",G:"#ff00ff",H:"#6464ff",I:"#ffafaf",L:"#ffafaf",K:"#6464ff",M:"#ffafaf",F:"#ffc800",P:"#ff00ff",S:"#00ff00",T:"#00ff00",W:"#ffc800",Y:"#ffc800",V:"#ffafaf"},cinema:{H:"blue",K:"blue",R:"blue",D:"red",E:"red",S:"green",T:"green",N:"green",Q:"green",A:"white",V:"white",L:"white",I:"white",M:"white",F:"magenta",W:"magenta",Y:"magenta",P:"brown",G:"brown",C:"yellow",B:"gray",Z:"gray",X:"gray","-":"gray",".":"gray"}},_c=ba(g6,([e,t])=>[e,ba(t,([r,n])=>[r,rt(n).toHex()])])});var hh,vT,h6,TT,QT=d(()=>{hh=p(k(),1);Wa();wT();vT=p($(),1);gh();h6=(0,vT.observer)(function({model:e}){let{colorSchemeName:t}=e;return hh.default.createElement(pn,{"data-testid":"color_scheme_menu",tooltip:"Color scheme",closeAfterItemClick:!0,anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"},menuItems:Object.keys(_c).map(r=>({label:r,type:"radio",checked:t===r,onClick:()=>{e.setColorSchemeName(r)}}))},hh.default.createElement(IT,null))}),TT=h6});var MT,_T,kT=d(()=>{"use client";Ee();MT=p(O(),1),_T=Y((0,MT.jsx)("path",{d:"M19 3h-4.18C14.4 1.84 13.3 1 12 1s-2.4.84-2.82 2H5c-1.1 0-2 .9-2 2v14c0 1.1.9 2 2 2h14c1.1 0 2-.9 2-2V5c0-1.1-.9-2-2-2m-7 0c.55 0 1 .45 1 1s-.45 1-1 1-1-.45-1-1 .45-1 1-1m2 14H7v-2h7zm3-4H7v-2h10zm0-4H7V7h10z"}),"Assignment")});var DT,Tf,Ch=d(()=>{"use client";Ee();DT=p(O(),1),Tf=Y((0,DT.jsx)("path",{d:"M20 6h-8l-2-2H4c-1.1 0-1.99.9-1.99 2L2 18c0 1.1.9 2 2 2h16c1.1 0 2-.9 2-2V8c0-1.1-.9-2-2-2m0 12H4V8h16z"}),"FolderOpen")});var NT,RT,LT=d(()=>{"use client";Ee();NT=p(O(),1),RT=Y((0,NT.jsx)("path",{d:"M3 18h18v-2H3zm0-5h18v-2H3zm0-7v2h18V6z"}),"Menu")});var yh,FT,PT=d(()=>{"use client";Ee();yh=p(O(),1),FT=Y([(0,yh.jsx)("circle",{cx:"12",cy:"12",r:"3.2"},"0"),(0,yh.jsx)("path",{d:"M9 2 7.17 4H4c-1.1 0-2 .9-2 2v12c0 1.1.9 2 2 2h16c1.1 0 2-.9 2-2V6c0-1.1-.9-2-2-2h-3.17L15 2zm3 15c-2.76 0-5-2.24-5-5s2.24-5 5-5 5 2.24 5 5-2.24 5-5 5"},"1")],"PhotoCamera")});var OT,GT,UT=d(()=>{"use client";Ee();OT=p(O(),1),GT=Y((0,OT.jsx)("path",{d:"M4.25 5.61C6.27 8.2 10 13 10 13v6c0 .55.45 1 1 1h2c.55 0 1-.45 1-1v-6s3.72-4.8 5.74-7.39c.51-.66.04-1.61-.79-1.61H5.04c-.83 0-1.3.95-.79 1.61"}),"FilterAlt")});var HT,VT,jT=d(()=>{"use client";Ee();HT=p(O(),1),VT=Y((0,HT.jsx)("path",{d:"M15.5 14h-.79l-.28-.27C15.41 12.59 16 11.11 16 9.5 16 5.91 13.09 3 9.5 3S3 5.91 3 9.5 5.91 16 9.5 16c1.61 0 3.09-.59 4.23-1.57l.27.28v.79l5 4.99L20.49 19zm-6 0C7.01 14 5 11.99 5 9.5S7.01 5 9.5 5 14 7.01 14 9.5 11.99 14 9.5 14"}),"Search")});var YT,$T,qT=d(()=>{"use client";Ee();YT=p(O(),1),$T=Y((0,YT.jsx)("path",{d:"M3 18h6v-2H3zM3 6v2h18V6zm0 7h12v-2H3z"}),"Sort")});var JT,WT,zT=d(()=>{"use client";Ee();JT=p(O(),1),WT=Y((0,JT.jsx)("path",{d:"M12 4.5C7 4.5 2.73 7.61 1 12c1.73 4.39 6 7.5 11 7.5s9.27-3.11 11-7.5c-1.73-4.39-6-7.5-11-7.5M12 17c-2.76 0-5-2.24-5-5s2.24-5 5-5 5 2.24 5 5-2.24 5-5 5m0-8c-1.66 0-3 1.34-3 3s1.34 3 3 3 3-1.34 3-3-1.34-3-3-3"}),"Visibility")});var XT={};bt(XT,{default:()=>E6});var de,KT,me,Qf,C6,y6,x6,E6,ZT=d(()=>{de=p(k(),1),KT=p(Ye(),1),me=p(V(),1),Qf=p($(),1),C6=(0,Qf.observer)(function({model:e}){let{featureFilters:t}=e;return de.default.createElement("div",null,de.default.createElement(me.Button,{onClick:()=>{for(let r of t.keys())e.setFilter(r,!0)}},"Toggle all on"),de.default.createElement(me.Button,{onClick:()=>{for(let r of t.keys())e.setFilter(r,!1)}},"Toggle all off"))}),y6=(0,Qf.observer)(function({model:e}){let{tidyInterProAnnotationTypes:t,tidyInterProAnnotations:r,fillPalette:n}=e,o=new Map;for(let i of r)o.set(i.accession,(o.get(i.accession)??0)+1);return de.default.createElement(de.default.Fragment,null,de.default.createElement(C6,{model:e}),de.default.createElement(me.Table,{size:"small"},de.default.createElement(me.TableHead,null,de.default.createElement(me.TableRow,null,de.default.createElement(me.TableCell,{padding:"checkbox"}),de.default.createElement(me.TableCell,null,"color"),de.default.createElement(me.TableCell,null,"accession"),de.default.createElement(me.TableCell,null,"name"),de.default.createElement(me.TableCell,null,"count"),de.default.createElement(me.TableCell,null,"description"))),de.default.createElement(me.TableBody,null,[...t.values()].map(({accession:i,name:a,description:s})=>de.default.createElement(me.TableRow,{key:i},de.default.createElement(me.TableCell,{padding:"checkbox"},de.default.createElement(me.Checkbox,{checked:e.featureFilters.get(i)??!1,onChange:()=>{e.setFilter(i,!e.featureFilters.get(i))}})),de.default.createElement(me.TableCell,null,de.default.createElement("div",{style:{width:20,height:20,background:n[i]}})),de.default.createElement(me.TableCell,null,i),de.default.createElement(me.TableCell,null,a),de.default.createElement(me.TableCell,null,o.get(i)),de.default.createElement(me.TableCell,null,s))))))}),x6=(0,Qf.observer)(function({onClose:e,model:t}){return de.default.createElement(KT.Dialog,{onClose:()=>{e()},open:!0,title:"Feature filters",maxWidth:"xl"},de.default.createElement(me.DialogContent,null,de.default.createElement(y6,{model:t})))}),E6=x6});async function kc(e,t,r=Mf.fetchAndMaybeUnzipText){let n=new AbortController;try{return await r(e,{signal:n.signal,statusCallback:o=>{let i=(0,Mf.statusMessageText)(o);t(i?{msg:i,onCancel:()=>{n.abort()}}:void 0)}})}finally{t(void 0)}}async function eQ(e,t){let r=await fetch(e,t);if(!r.ok)throw new Error(`HTTP ${r.status} fetching ${e} ${await r.text()}`);return r}async function xh(e,t){return(await eQ(e,t)).text()}async function _f(e,t){return(await eQ(e,t)).json()}function tQ(e,t){return new Promise((r,n)=>{if(t?.aborted)n(new DOMException("Aborted","AbortError"));else{let o=setTimeout(r,e);t?.addEventListener("abort",()=>{clearTimeout(o),n(new DOMException("Aborted","AbortError"))})}})}function yo(e){return e instanceof DOMException&&e.name==="AbortError"}var Mf,kf=d(()=>{Mf=p(Be(),1)});var oQ={};bt(oQ,{default:()=>I6});var Qe,rQ,Eh,Fe,nQ,b6,I6,iQ=d(()=>{Qe=p(k(),1),rQ=p(Ye(),1),Eh=p(Be(),1),Fe=p(V(),1),nQ=p($(),1);kf();b6=(0,nQ.observer)(function({handleClose:e,model:t}){let[r,n]=(0,Qe.useState)(),[o,i]=(0,Qe.useState)("file"),[a,s]=(0,Qe.useState)("");return Qe.default.createElement(rQ.Dialog,{maxWidth:"xl",title:"Open protein domains from file",onClose:()=>{e()},open:!0},Qe.default.createElement(Fe.DialogContent,null,Qe.default.createElement("div",null,Qe.default.createElement(Fe.Typography,null,"Open a JSON file of InterProScan results that you run remotely on EBI servers or locally"),Qe.default.createElement("div",{style:{display:"flex",margin:30}},Qe.default.createElement(Fe.FormControl,{component:"fieldset"},Qe.default.createElement(Fe.RadioGroup,{value:o,onChange:c=>{i(c.target.value)}},Qe.default.createElement(Fe.FormControlLabel,{value:"url",control:Qe.default.createElement(Fe.Radio,null),label:"URL"}),Qe.default.createElement(Fe.FormControlLabel,{value:"file",control:Qe.default.createElement(Fe.Radio,null),label:"File"}))),o==="url"?Qe.default.createElement("div",null,Qe.default.createElement(Fe.Typography,null,"Open a InterProScan JSON file remote URL"),Qe.default.createElement(Fe.TextField,{label:"URL",value:a,onChange:c=>{s(c.target.value)}})):null,o==="file"?Qe.default.createElement("div",{style:{paddingTop:20}},Qe.default.createElement(Fe.Typography,null,"Open a InterProScan JSON file file from your local drive"),Qe.default.createElement(Fe.Button,{variant:"outlined",component:"label"},"Choose File",Qe.default.createElement("input",{type:"file",hidden:!0,onChange:({target:c})=>{let l=c.files?.[0];l&&n(l)}}))):null))),Qe.default.createElement(Fe.DialogActions,null,Qe.default.createElement(Fe.Button,{variant:"contained",color:"primary",onClick:()=>{(async()=>{try{let c=r?JSON.parse(await r.text()):await _f(a);t.setDomains(Object.fromEntries(c.results.map(l=>[l.xref[0].id,l]))),(0,Eh.getSession)(t).notify("Loaded interproscan results","success")}catch(c){console.error(c),(0,Eh.getSession)(t).notifyError(`${c}`,c)}finally{t.setStatus()}})(),e()}},"Open results")))}),I6=b6});var aQ=d(()=>{});function za(e,t="node",r=0){let n=`${t}-${r}`;return{...e,id:n,name:e.name||n,children:e.children?.map((o,i)=>za(o,`${n}-${i}`,r+1))||[]}}var bh=d(()=>{});var or,Ka=d(()=>{or=class{getTree(){return{id:"root",name:"root",noTree:!0,children:this.getNames().map(t=>({id:t,children:[],name:t}))}}getRowData(t){}getStructures(){return{}}getHeader(){return{}}get alignmentNames(){return[]}get seqConsensus(){}get secondaryStructureConsensus(){}get tracks(){return[]}}});function Xa(e){return e>=w6&&e<=S6}var sQ,cQ,w6,S6,lQ,uQ,Yn,Ih=d(()=>{Ka();sQ=65,cQ=90,w6=97,S6=122,lQ=45,uQ=46;Yn=class extends or{MSA;orderedNames;constructor(t){super();let r=[],n=[];for(let o of t.split(">")){if(!/\S/.test(o))continue;let i=o.indexOf(`
 `);if(i===-1)continue;let a=o.slice(0,i).replace(/\r$/,""),s=a.indexOf(" "),c=s===-1?a:a.slice(0,s);c&&(r.push(o.slice(i+1).replaceAll(/\s/g,"")),n.push(c))}this.orderedNames=n,this.MSA={seqdata:this.expandA3M(r,n)}}static sniff(t){if(!t.startsWith(">"))return!1;let r=[];for(let a of t.split(">")){if(!/\S/.test(a))continue;let s=a.indexOf(`
-`);if(s===-1)continue;let c=a.slice(s+1).replaceAll(/\s/g,"");c&&r.push(c)}if(r.length<2||new Set(r.map(a=>a.length)).size===1)return!1;let n=!1,o=-1,i=!0;for(let a of r){let s=0;for(let c=0;c<a.length;c++){let l=a.charCodeAt(c);Pi(l)?n=!0:(l>=tb&&l<=rb||l===nb)&&s++}o===-1?o=s:s!==o&&(i=!1)}return n&&i}expandA3M(t,r){let n=r.length;if(n===0)return{};let o=[],i=[];for(let l=0;l<n;l++){let A=t[l],u=[],m=[],d=0;for(;d<A.length;){let g=A.charCodeAt(d);if(g>=tb&&g<=rb||g===nb){u.push(A[d]);let C="",y=d+1;for(;y<A.length;){let I=A.charCodeAt(y);if(Pi(I)||I===ob)C+=A[y],y++;else break}m.push(C),d=y}else if(g===ob)d++;else if(Pi(g)){let C="";for(;d<A.length&&Pi(A.charCodeAt(d));)C+=A[d],d++;u.push(""),m.push(C)}else d++}o.push(u),i.push(m)}let a=Math.max(...o.map(l=>l.length),0),s=new Array(a).fill(0);for(let l=0;l<n;l++){let A=i[l];for(let u=0;u<A.length;u++){let m=0;for(let d of A[u])Pi(d.charCodeAt(0))&&m++;m>s[u]&&(s[u]=m)}}let c={};for(let l=0;l<n;l++){let A=o[l],u=i[l],m=[];for(let d=0;d<a;d++){let g=s[d];if(d<A.length){let C=A[d],y=u[d]||"";m.push(C||"-");let I="";for(let b of y)Pi(b.charCodeAt(0))&&(I+=b.toUpperCase());m.push(I);let E=g-I.length;E>0&&m.push(".".repeat(E))}else m.push("-"),g>0&&m.push(".".repeat(g))}c[r[l]]=m.join("")}return c}getMSA(){return this.MSA}getNames(){return this.orderedNames}getRow(t){return this.MSA.seqdata[t]||""}getWidth(){let t=Object.keys(this.MSA.seqdata)[0];return t?this.getRow(t).length:0}}});function iL(e){let t=/\(?(\d+(\.\d+)+)\)?/.exec(e);return t&&t.length>1?t[1]:""}function ab(e){let t=["CLUSTAL","PROBCONS","MUSCLE","MSAPROBS","Kalign"];t.some(n=>e.startsWith(n))||console.warn(`${e} is not a known CLUSTAL header: ${t.join(",")}, proceeding but could indicate an issue`);let r=iL(e);return{info:e,version:r}}function fl(e){let t=e.next();for(;!t.done&&t.value.trim()==="";)t=e.next();return t.value}function aL(e){let t=e.split(/\s+/),r=e.slice(t[0].length),n=t[0].length+r.indexOf(t[1]),o=n+t[1].length;return[n,o]}function ib(e){let t=fl(e),r=[],n="";if(!t)return;for(;t;)t.startsWith(" ")?n=t:r.push(t),t=e.next().value;let[o,i]=aL(r[0]),s=r.map(u=>u.split(/\s+/)).map(u=>u[0]),c=r.map(u=>u.slice(o,i)),l=n.slice(o,i),A=c[0].length-l.length;return A&&(l+=" ".repeat(A)),{ids:s,seqs:c,consensus:l}}function sb(e){let t,r=ib(e);if(r!==void 0)for(;t=ib(e);){for(let n=0;n<t.seqs.length;n++)r.seqs[n]+=t.seqs[n];r.consensus+=t.consensus}return r}var Wd=p(()=>{});var cb=p(()=>{Wd()});function sL(e){let t=fl(e);if(!t)throw new Error("Empty file received");let r=ab(t),n=sb(e);if(n===void 0)throw new Error("No blocks parsed");let o=n.seqs.map((a,s)=>({id:n.ids[s],seq:a})),{consensus:i}=n;if(i.length!==o[0].seq.length)throw new Error(`Consensus length != sequence length. Con ${i.length} seq ${o[0].seq.length}`);return{consensus:i,alns:o,header:r}}function lb(e){let t=e.split(`
-`)[Symbol.iterator]();return sL(t)}var Ab=p(()=>{cb();Wd()});var Nn,$d=p(()=>{Ab();Fi();Nn=class extends Vt{MSA;constructor(t){super(),this.MSA=lb(t)}getMSA(){return this.MSA}getRow(t){return this.MSA.alns.find(r=>r.id===t)?.seq??""}getWidth(){return this.MSA.alns[0]?.seq.length??0}getHeader(){return this.MSA.header}getNames(){return this.MSA.alns.map(t=>t.id)}get seqConsensus(){return this.MSA.consensus}}});function ub(e){let t=e.split(`
-`).map(i=>i.trim()).filter(i=>!!i),r=[],n=[];for(let i of t)if(i.startsWith("SEQ"))r.push(i);else{if(i.startsWith("DATA"))continue;if(i.startsWith("//"))break;n.push(i)}let o=r.map(i=>{let[,a,s,c,l,A,u,m,d]=i.split(" ");return{species:a,protein:s,chr:c,start:+l,end:+A,strand:+u,geneId:m,unknown:d,seq:""}});for(let i of n)for(let a=0;a<r.length;a++)o[a].seq+=i[a];return o}function dl(e){let t=e.split(`
-`).map(i=>i.trim()).filter(i=>!!i),r=[],n="";for(let i of t)if(i.startsWith("SEQ"))r.push(i);else{if(i.startsWith("DATA"))continue;if(i.startsWith("//"))break;n=i}let o=r.map(i=>{let[,a,s,c,l,A,u,m,d]=i.split(" ");return{species:a,protein:s,chr:c,start:+l,end:+A,strand:+u,geneId:m,unknown:d}});return{tree:n,seqs:o}}var Kd=p(()=>{});var Ln,Xd=p(()=>{Kd();Fi();Ln=class extends Vt{MSA;constructor(t){super(),this.MSA=ub(t)}getMSA(){return this.MSA}getRow(t){return this.MSA.find(r=>r.protein===t)?.seq??""}getWidth(){return this.MSA[0]?.seq.length??0}getNames(){return this.MSA.map(t=>t.protein)}}});var Rn,Zd=p(()=>{Fi();Rn=class extends Vt{MSA;orderedNames=[];constructor(t){super();let r={},n={};for(let o of t.split(">")){if(!/\S/.test(o))continue;let i=o.indexOf(`
-`);if(i===-1)continue;let a=o.slice(0,i).replace(/\r$/,""),s=a.indexOf(" "),c=s===-1?a:a.slice(0,s);c&&(r[c]=o.slice(i+1).replaceAll(/\s/g,""),this.orderedNames.push(c),c.includes(":")&&(n[c.replaceAll(":","_")]=c))}this.MSA={seqdata:r,colonNormalized:n}}getMSA(){return this.MSA}getNames(){return this.orderedNames}getRow(t){return this.MSA.seqdata[t]??this.MSA.seqdata[this.MSA.colonNormalized[t]??""]??""}getWidth(){let t=this.orderedNames[0];return t===void 0?0:this.getRow(t).length}}});function xo(e){let t=[],r=[],n=e.replace(/'((?:[^']|'')*)'/g,(a,s)=>{let c=r.length;return r.push(s.replaceAll("''","'")),`__Q${c}__`}),o={},i=n.split(/\s*(;|\(|\)|,|:)\s*/);for(let a=0;a<i.length;a++){let c=i[a].replace(/^__Q(\d+)__$/,(A,u)=>r[Number(u)]),l={};switch(c){case"(":o.children=[l],t.push(o),o=l;break;case",":t.at(-1)?.children.push(l),o=l;break;case")":o=t.pop();break;case":":break;default:{let A=i[a-1];A===")"||A==="("||A===","?o.name=c:A===":"&&(o.length=Number.parseFloat(c))}}}return o}var em=p(()=>{});function fb(){return{gf:{},gc:{},gs:{},gr:{},seqname:[],seqdata:{}}}function $a(e,t){if(e)return e;if(t)throw new Error("No format header: # STOCKHOLM 1.0");return fb()}function Ka(e){return db.test(e)}function mb(e,t){let r=t??{},n=[],o=null,i=e.split(`
-`);for(let a of i){let s;if(db.test(a))o=fb();else if(cL.test(a))o&&n.push(o),o=null;else if(s=lL.exec(a)){o=$a(o,!!r.strict);let c=s[1];o.gf[c]||(o.gf[c]=[]),o.gf[c].push(s[2])}else if(s=AL.exec(a)){o=$a(o,!!r.strict);let c=s[1];o.gc[c]||(o.gc[c]=""),o.gc[c]+=s[2]}else if(s=uL.exec(a)){o=$a(o,!!r.strict);let c=s[1],l=s[2],A=s[3];o.gs[l]||(o.gs[l]={}),o.gs[l][c]||(o.gs[l][c]=[]),o.gs[l][c].push(A)}else if(s=fL.exec(a)){o=$a(o,!!r.strict);let c=s[1],l=s[2],A=s[3];o.gr[l]||(o.gr[l]={}),o.gr[l][c]||(o.gr[l][c]=""),o.gr[l][c]+=A}else if(s=dL.exec(a)){o=$a(o,!!r.strict);let c=s[1],l=s[2];o.seqdata[c]||(o.seqdata[c]="",o.seqname.push(c)),o.seqdata[c]+=l}else if(mL.test(a)&&r.strict)throw new Error("Malformed line")}return o&&n.push(o),n}var db,cL,lL,AL,uL,fL,dL,mL,tm=p(()=>{db=/^# STOCKHOLM 1.0/,cL=/^\/\/\s*$/,lL=/^#=GF\s+(\S+)\s+(.*?)\s*$/,AL=/^#=GC\s+(\S+)\s+(.*?)\s*$/,uL=/^#=GS\s+(\S+)\s+(\S+)\s+(.*?)\s*$/,fL=/^#=GR\s+(\S+)\s+(\S+)\s+(.*?)\s*$/,dL=/^\s*(\S+)\s+(\S+)\s*$/,mL=/\S/});var Fn,rm=p(()=>{em();tm();Yd();Fi();tm();Fn=class extends Vt{data;MSA;constructor(t,r){super();let n=mb(t);this.data=n;let o=n[r]??n[0];if(!o)throw new Error("No alignments found in Stockholm file");this.MSA=o}getMSA(){return this.MSA}getRow(t){return this.MSA.seqdata[t]??""}getWidth(){let t=Object.keys(this.MSA.seqdata)[0];return t===void 0?0:this.getRow(t).length}get alignmentNames(){return this.data.map((t,r)=>t.gf.DE?.[0]??`Alignment ${r+1}`)}getHeader(){let t=this.MSA.gs.AC??{},r=this.MSA.gs.DR??{};return{General:this.MSA.gf,Accessions:Object.fromEntries(Object.entries(t).map(([n,o])=>[n,o[0]])),Dbxref:Object.fromEntries(Object.entries(r).map(([n,o])=>[n,o.join("; ")]))}}getRowData(t){return{name:t,accession:this.MSA.gs.AC?.[t]?.[0],dbxref:this.MSA.gs.DR?.[t]?.join("; ")}}getNames(){return Object.keys(this.MSA.seqdata)}getStructures(){let t=/PDB; +(\S+) +(\S); ([0-9]+)-([0-9]+)/,r=this.MSA.gs.DR??{},n={};for(let[o,i]of Object.entries(r))for(let a of i){let s=t.exec(a);s&&(n[o]??=[]).push({pdb:s[1].toLowerCase(),chain:s[2],startPos:+s[3],endPos:+s[4]})}return n}getTree(){let t=this.MSA.gf.NH?.[0];return t?Ri(xo(t)):super.getTree()}get seqConsensus(){return this.MSA.gc.seq_cons}get secondaryStructureConsensus(){return this.MSA.gc.SS_cons}get tracks(){return[{id:"seqConsensus",name:"Sequence consensus",data:this.seqConsensus,customColorScheme:{}},{id:"secondaryStruct",name:"Secondary-structure",data:this.secondaryStructureConsensus,customColorScheme:{"<":"lightblue","(":"lightblue","[":"lightblue","{":"lightblue",">":"pink",")":"pink","]":"pink","}":"pink"}}]}}});function nm(e,t=0,r){return r==="stockholm"?new Fn(e,t):r==="a3m"?new An(e):r==="fasta"?new Rn(e):r==="emf"?new Ln(e):r==="clustal"?new Nn(e):Ka(e)?new Fn(e,t):An.sniff(e)?new An(e):e.startsWith(">")?new Rn(e):e.startsWith("SEQ")?new Ln(e):new Nn(e)}function om(e){return e.replaceAll(/[.-]/g,"")}var pb=p(()=>{zd();$d();Xd();Zd();rm();Kd();em();zd();$d();Xd();Zd();rm()});function pL(e){try{return decodeURIComponent(e)}catch{return e}}function gL(e){return e?Object.fromEntries(e.split(";").map(t=>t.trim()).filter(t=>!!t).map(t=>{let r=t.indexOf("="),n=(r===-1?t:t.slice(0,r)).trim(),o=r===-1?void 0:t.slice(r+1);return[n,o?o.split(",").map(i=>pL(i).trim()).join(" "):void 0]}).filter(([t])=>t!=="")):{}}function ml(e){return e?e.split(`
-`).map(t=>t.trim()).filter(t=>!!t&&!t.startsWith("#")).map(t=>{let r=t.split("	"),[n,o,i,a,s,c,l,A]=r,u=r[8];return{seq_id:n??"",source:o??"",type:i??"",start:Number(a)||0,end:Number(s)||0,score:Number(c)||0,strand:l??".",phase:A??".",...gL(u)}}):[]}var gb=p(()=>{});function CL({type:e,strand:t}){let r=t==="+"?1:t==="-"?-1:void 0;return hL.has(e)?r:void 0}function pl(e){let t=new Map;for(let n of e){let o=t.get(n.seq_id);o?o.push(n):t.set(n.seq_id,[n])}let r={};for(let[n,o]of t){let i=new Map,a=new Map;for(let c of o){let l=c.Name||c.ID||`${c.source}_${c.start}_${c.end}`,A=c.signature_desc||c.Name||l,u=c.Ontology_term||c.description||c.Note||A;a.has(l)||a.set(l,{name:A,description:u,accession:l,featureType:c.type});let m={start:c.start,end:c.end,strand:CL(c)},d=i.get(l);d?d.push(m):i.set(l,[m])}let s=[];for(let[c,l]of i){let A=a.get(c);s.push({signature:{entry:A},locations:l})}r[n]={matches:s,xref:[{id:n}]}}return r}var hL,hb=p(()=>{hL=new Set(["gene","pseudogene","mRNA","transcript","primary_transcript","ncRNA","tRNA","rRNA","snRNA","snoRNA","miRNA","lnc_RNA"])});var Cb=p(()=>{});var Eb=p(()=>{gb();hb();Cb()});var im=p(()=>{eb();Yd();pb();Eb()});async function yL({seq:e,onProgress:t,onJobId:r,programs:n,model:o,signal:i}){let a=await Jd(`${am}/iprscan5/run`,{method:"POST",body:new URLSearchParams({email:"colin.diesh@gmail.com",sequence:e,programs:n.join(",")}),signal:i});r?.(a),await bL({jobId:a,onProgress:t,signal:i}),await BL({jobId:a,model:o,onProgress:t,signal:i})}function wL(e,t){return Al(`${am}/iprscan5/result/${e}/json`,{signal:t})}async function bL({onProgress:e,jobId:t,signal:r}){let n=`${am}/iprscan5/status/${t}`,o=360;try{let i=!1;for(let a=0;a<o&&!i;a++){for(let c=0;c<10;c++)await Ww(1e3,r),e({msg:`Checking status ${10-c}`,url:n});let s=(await Jd(n,{signal:r})).trim();if(s==="FINISHED")i=!0;else if(s==="FAILURE"||s==="ERROR"||s==="NOT_FOUND")throw new Error(`InterProScan job ${t} ended with status: ${s}`)}if(!i)throw new Error(`InterProScan job ${t} did not finish after ${o} status checks`)}finally{e()}}async function Ib({algorithm:e,seq:t,programs:r,onJobId:n,onProgress:o,model:i,signal:a}){try{if(o({msg:`Launching ${e} MSA`}),e==="interproscan")await yL({seq:t,onJobId:n,onProgress:o,programs:r,model:i,signal:a});else throw new Error("unknown algorithm")}catch(s){if(Dn(s))(0,Xa.getSession)(i).notify("Cancelled InterProScan query","info");else throw s}finally{o()}}async function BL({jobId:e,model:t,onProgress:r,signal:n}){try{r({msg:`Downloading results of ${e} (for larger sequences this can be slow, click status to download and upload in the manual tab)`,url:`https://www.ebi.ac.uk/Tools/services/rest/iprscan5/result/${e}/json`});let o=await wL(e,n);t.setDomains(Object.fromEntries(o.results.map(i=>[i.xref[0]?.id,i]).filter(i=>i[0]!==void 0))),(0,Xa.getSession)(t).notify(`Loaded interproscan ${e} results`,"success")}catch(o){Dn(o)?(0,Xa.getSession)(t).notify("Cancelled InterProScan query","info"):(console.error(o),(0,Xa.getSession)(t).notifyError(`${o}`,o))}finally{r()}}var Xa,am,xb=p(()=>{Xa=f(de(),1);ul();am="https://www.ebi.ac.uk/Tools/services/rest"});var Bb={};dt(Bb,{default:()=>QL});var Me,yb,wb,Yt,bb,SL,QL,Sb=p(()=>{Me=f(M(),1),yb=f(Ne(),1),wb=f(de(),1),Yt=f(O(),1),bb=f(H(),1);im();xb();SL=(0,bb.observer)(function({handleClose:e,model:t}){let[r,n]=(0,Me.useState)([{name:"NCBIfam",description:"NCBI RefSeq FAMs including TIGRFAMs",category:"Families, domains, sites & repeats",checked:!0},{name:"SFLD",description:"Structure function linkage database",category:"Families, domains, sites & repeats",checked:!0},{name:"Phobius",checked:!0,description:"A combined transmembrane topology and signal peptide predictor",category:"Other sequence features"},{name:"SignalP",checked:!0,category:"Other sequence features"},{name:"SignalP_EUK",category:"Other category",checked:!0},{name:"SignalP_GRAM_POSITIVE",category:"Other category",checked:!0},{name:"SignalP_GRAM_NEGATIVE",checked:!0,category:"Other category"},{name:"SuperFamily",category:"Structural domains",checked:!0},{name:"Panther",category:"Families, domains, sites & repeats",checked:!0},{name:"Gene3d",category:"Structural domains",checked:!0},{name:"HAMAP",category:"Families, domains, sites & repeats",checked:!0},{name:"PrositeProfiles",category:"Families, domains, sites & repeats",checked:!0},{name:"PrositePatterns",category:"Families, domains, sites & repeats",checked:!0},{name:"Coils",category:"Other sequence features",checked:!0},{name:"SMART",category:"Families, domains, sites & repeats",checked:!0},{name:"CDD",description:"Conserved Domains Database",category:"Families, domains, sites & repeats",checked:!0},{name:"PRINTS",category:"Families, domains, sites & repeats",checked:!0},{name:"PfamA",category:"Families, domains, sites & repeats",checked:!0},{name:"MobiDBLite",checked:!0,category:"Other sequence features"},{name:"PIRSF",checked:!0,category:"Other category"},{name:"TMHMM",checked:!0,category:"Other sequence features"},{name:"AntiFam",checked:!0,category:"Other category"},{name:"FunFam",checked:!0,category:"Other category"},{name:"PIRSR",checked:!0,category:"Families, domains, sites & repeats"}]),o=r.filter(s=>s.checked).map(s=>s.name),[i,a]=(0,Me.useState)(!1);return Me.default.createElement(yb.Dialog,{maxWidth:"xl",title:"Query InterProScan API for domains",onClose:()=>{e()},open:!0},Me.default.createElement(Yt.DialogContent,null,Me.default.createElement(Yt.Typography,null,"This will run InterProScan via the InterProScan API on all rows of the current MSA"),Me.default.createElement(Yt.Button,{onClick:()=>{a(!i)}},i?"Hide":"Show"," advanced options"),i?Me.default.createElement("div",null,Me.default.createElement(Yt.Typography,null,"Select algorithms for InterProScan to run"),Me.default.createElement("div",null,Me.default.createElement(Yt.Button,{variant:"contained",color:"secondary",onClick:()=>{n(r.map(s=>({...s,checked:!1})))}},"Select none"),Me.default.createElement(Yt.Button,{variant:"contained",color:"primary",onClick:()=>{n(r.map(s=>({...s,checked:!0})))}},"Select all")),Me.default.createElement("table",null,Me.default.createElement("tbody",null,r.toSorted((s,c)=>s.category.localeCompare(c.category)).map(({name:s,checked:c,category:l})=>Me.default.createElement("tr",{key:s},Me.default.createElement("td",null,Me.default.createElement("input",{type:"checkbox",key:s,checked:c,onChange:()=>{n(r.map(A=>A.name===s?{...A,checked:!A.checked}:A))}})),Me.default.createElement("td",null,s),Me.default.createElement("td",null,l)))))):null),Me.default.createElement(Yt.DialogActions,null,Me.default.createElement(Yt.Button,{variant:"contained",color:"secondary",onClick:()=>{e()}},"Cancel"),Me.default.createElement(Yt.Button,{variant:"contained",color:"primary",onClick:()=>{let s=new AbortController;(async()=>{try{let{rows:c}=t;if(c.length>140)throw new Error("Too many sequences, please run InterProScan offline");await Ib({algorithm:"interproscan",programs:o,seq:c.map(l=>[l[0],om(l[1])]).filter(l=>!!l[1]).map(l=>`>${l[0]}
+`);if(s===-1)continue;let c=a.slice(s+1).replaceAll(/\s/g,"");c&&r.push(c)}if(r.length<2||new Set(r.map(a=>a.length)).size===1)return!1;let n=!1,o=-1,i=!0;for(let a of r){let s=0;for(let c=0;c<a.length;c++){let l=a.charCodeAt(c);Xa(l)?n=!0:(l>=sQ&&l<=cQ||l===lQ)&&s++}o===-1?o=s:s!==o&&(i=!1)}return n&&i}expandA3M(t,r){let n=r.length;if(n===0)return{};let o=[],i=[];for(let l=0;l<n;l++){let u=t[l],A=[],m=[],f=0;for(;f<u.length;){let g=u.charCodeAt(f);if(g>=sQ&&g<=cQ||g===lQ){A.push(u[f]);let y="",E=f+1;for(;E<u.length;){let b=u.charCodeAt(E);if(Xa(b)||b===uQ)y+=u[E],E++;else break}m.push(y),f=E}else if(g===uQ)f++;else if(Xa(g)){let y="";for(;f<u.length&&Xa(u.charCodeAt(f));)y+=u[f],f++;A.push(""),m.push(y)}else f++}o.push(A),i.push(m)}let a=Math.max(...o.map(l=>l.length),0),s=new Array(a).fill(0);for(let l=0;l<n;l++){let u=i[l];for(let A=0;A<u.length;A++){let m=0;for(let f of u[A])Xa(f.charCodeAt(0))&&m++;m>s[A]&&(s[A]=m)}}let c={};for(let l=0;l<n;l++){let u=o[l],A=i[l],m=[];for(let f=0;f<a;f++){let g=s[f];if(f<u.length){let y=u[f],E=A[f]||"";m.push(y||"-");let b="";for(let B of E)Xa(B.charCodeAt(0))&&(b+=B.toUpperCase());m.push(b);let x=g-b.length;x>0&&m.push(".".repeat(x))}else m.push("-"),g>0&&m.push(".".repeat(g))}c[r[l]]=m.join("")}return c}getMSA(){return this.MSA}getNames(){return this.orderedNames}getRow(t){return this.MSA.seqdata[t]||""}getWidth(){let t=Object.keys(this.MSA.seqdata)[0];return t?this.getRow(t).length:0}}});function B6(e){let t=/\(?(\d+(\.\d+)+)\)?/.exec(e);return t&&t.length>1?t[1]:""}function AQ(e){let t=["CLUSTAL","PROBCONS","MUSCLE","MSAPROBS","Kalign"];t.some(n=>e.startsWith(n))||console.warn(`${e} is not a known CLUSTAL header: ${t.join(",")}, proceeding but could indicate an issue`);let r=B6(e);return{info:e,version:r}}function Df(e){let t=e.next();for(;!t.done&&t.value.trim()==="";)t=e.next();return t.value}function v6(e){let t=e.split(/\s+/),r=e.slice(t[0].length),n=t[0].length+r.indexOf(t[1]),o=n+t[1].length;return[n,o]}function fQ(e){let t=Df(e),r=[],n="";if(!t)return;for(;t;)t.startsWith(" ")?n=t:r.push(t),t=e.next().value;let[o,i]=v6(r[0]),s=r.map(A=>A.split(/\s+/)).map(A=>A[0]),c=r.map(A=>A.slice(o,i)),l=n.slice(o,i),u=c[0].length-l.length;return u&&(l+=" ".repeat(u)),{ids:s,seqs:c,consensus:l}}function dQ(e){let t,r=fQ(e);if(r!==void 0)for(;t=fQ(e);){for(let n=0;n<t.seqs.length;n++)r.seqs[n]+=t.seqs[n];r.consensus+=t.consensus}return r}var wh=d(()=>{});var mQ=d(()=>{wh()});function T6(e){let t=Df(e);if(!t)throw new Error("Empty file received");let r=AQ(t),n=dQ(e);if(n===void 0)throw new Error("No blocks parsed");let o=n.seqs.map((a,s)=>({id:n.ids[s],seq:a})),{consensus:i}=n;if(i.length!==o[0].seq.length)throw new Error(`Consensus length != sequence length. Con ${i.length} seq ${o[0].seq.length}`);return{consensus:i,alns:o,header:r}}function pQ(e){let t=e.split(`
+`)[Symbol.iterator]();return T6(t)}var gQ=d(()=>{mQ();wh()});var xo,Sh=d(()=>{gQ();Ka();xo=class extends or{MSA;constructor(t){super(),this.MSA=pQ(t)}getMSA(){return this.MSA}getRow(t){return this.MSA.alns.find(r=>r.id===t)?.seq??""}getWidth(){return this.MSA.alns[0]?.seq.length??0}getHeader(){return this.MSA.header}getNames(){return this.MSA.alns.map(t=>t.id)}get seqConsensus(){return this.MSA.consensus}}});function hQ(e){let t=e.split(`
+`).map(i=>i.trim()).filter(i=>!!i),r=[],n=[];for(let i of t)if(i.startsWith("SEQ"))r.push(i);else{if(i.startsWith("DATA"))continue;if(i.startsWith("//"))break;n.push(i)}let o=r.map(i=>{let[,a,s,c,l,u,A,m,f]=i.split(" ");return{species:a,protein:s,chr:c,start:+l,end:+u,strand:+A,geneId:m,unknown:f,seq:""}});for(let i of n)for(let a=0;a<r.length;a++)o[a].seq+=i[a];return o}function Nf(e){let t=e.split(`
+`).map(i=>i.trim()).filter(i=>!!i),r=[],n="";for(let i of t)if(i.startsWith("SEQ"))r.push(i);else{if(i.startsWith("DATA"))continue;if(i.startsWith("//"))break;n=i}let o=r.map(i=>{let[,a,s,c,l,u,A,m,f]=i.split(" ");return{species:a,protein:s,chr:c,start:+l,end:+u,strand:+A,geneId:m,unknown:f}});return{tree:n,seqs:o}}var Bh=d(()=>{});var Eo,vh=d(()=>{Bh();Ka();Eo=class extends or{MSA;constructor(t){super(),this.MSA=hQ(t)}getMSA(){return this.MSA}getRow(t){return this.MSA.find(r=>r.protein===t)?.seq??""}getWidth(){return this.MSA[0]?.seq.length??0}getNames(){return this.MSA.map(t=>t.protein)}}});var bo,Th=d(()=>{Ka();bo=class extends or{MSA;orderedNames=[];constructor(t){super();let r={},n={};for(let o of t.split(">")){if(!/\S/.test(o))continue;let i=o.indexOf(`
+`);if(i===-1)continue;let a=o.slice(0,i).replace(/\r$/,""),s=a.indexOf(" "),c=s===-1?a:a.slice(0,s);c&&(r[c]=o.slice(i+1).replaceAll(/\s/g,""),this.orderedNames.push(c),c.includes(":")&&(n[c.replaceAll(":","_")]=c))}this.MSA={seqdata:r,colonNormalized:n}}getMSA(){return this.MSA}getNames(){return this.orderedNames}getRow(t){return this.MSA.seqdata[t]??this.MSA.seqdata[this.MSA.colonNormalized[t]??""]??""}getWidth(){let t=this.orderedNames[0];return t===void 0?0:this.getRow(t).length}}});function gi(e){let t=[],r=[],n=e.replace(/'((?:[^']|'')*)'/g,(a,s)=>{let c=r.length;return r.push(s.replaceAll("''","'")),`__Q${c}__`}),o={},i=n.split(/\s*(;|\(|\)|,|:)\s*/);for(let a=0;a<i.length;a++){let c=i[a].replace(/^__Q(\d+)__$/,(u,A)=>r[Number(A)]),l={};switch(c){case"(":o.children=[l],t.push(o),o=l;break;case",":t.at(-1)?.children.push(l),o=l;break;case")":o=t.pop();break;case":":break;default:{let u=i[a-1];u===")"||u==="("||u===","?o.name=c:u===":"&&(o.length=Number.parseFloat(c))}}}return o}var Qh=d(()=>{});function CQ(){return{gf:{},gc:{},gs:{},gr:{},seqname:[],seqdata:{}}}function Dc(e,t){if(e)return e;if(t)throw new Error("No format header: # STOCKHOLM 1.0");return CQ()}function Nc(e){return yQ.test(e)}function xQ(e,t){let r=t??{},n=[],o=null,i=e.split(`
+`);for(let a of i){let s;if(yQ.test(a))o=CQ();else if(Q6.test(a))o&&n.push(o),o=null;else if(s=M6.exec(a)){o=Dc(o,!!r.strict);let c=s[1];o.gf[c]||(o.gf[c]=[]),o.gf[c].push(s[2])}else if(s=_6.exec(a)){o=Dc(o,!!r.strict);let c=s[1];o.gc[c]||(o.gc[c]=""),o.gc[c]+=s[2]}else if(s=k6.exec(a)){o=Dc(o,!!r.strict);let c=s[1],l=s[2],u=s[3];o.gs[l]||(o.gs[l]={}),o.gs[l][c]||(o.gs[l][c]=[]),o.gs[l][c].push(u)}else if(s=D6.exec(a)){o=Dc(o,!!r.strict);let c=s[1],l=s[2],u=s[3];o.gr[l]||(o.gr[l]={}),o.gr[l][c]||(o.gr[l][c]=""),o.gr[l][c]+=u}else if(s=N6.exec(a)){o=Dc(o,!!r.strict);let c=s[1],l=s[2];o.seqdata[c]||(o.seqdata[c]="",o.seqname.push(c)),o.seqdata[c]+=l}else if(R6.test(a)&&r.strict)throw new Error("Malformed line")}return o&&n.push(o),n}var yQ,Q6,M6,_6,k6,D6,N6,R6,Mh=d(()=>{yQ=/^# STOCKHOLM 1.0/,Q6=/^\/\/\s*$/,M6=/^#=GF\s+(\S+)\s+(.*?)\s*$/,_6=/^#=GC\s+(\S+)\s+(.*?)\s*$/,k6=/^#=GS\s+(\S+)\s+(\S+)\s+(.*?)\s*$/,D6=/^#=GR\s+(\S+)\s+(\S+)\s+(.*?)\s*$/,N6=/^\s*(\S+)\s+(\S+)\s*$/,R6=/\S/});var Io,_h=d(()=>{Qh();Mh();bh();Ka();Mh();Io=class extends or{data;MSA;constructor(t,r){super();let n=xQ(t);this.data=n;let o=n[r]??n[0];if(!o)throw new Error("No alignments found in Stockholm file");this.MSA=o}getMSA(){return this.MSA}getRow(t){return this.MSA.seqdata[t]??""}getWidth(){let t=Object.keys(this.MSA.seqdata)[0];return t===void 0?0:this.getRow(t).length}get alignmentNames(){return this.data.map((t,r)=>t.gf.DE?.[0]??`Alignment ${r+1}`)}getHeader(){let t=this.MSA.gs.AC??{},r=this.MSA.gs.DR??{};return{General:this.MSA.gf,Accessions:Object.fromEntries(Object.entries(t).map(([n,o])=>[n,o[0]])),Dbxref:Object.fromEntries(Object.entries(r).map(([n,o])=>[n,o.join("; ")]))}}getRowData(t){return{name:t,accession:this.MSA.gs.AC?.[t]?.[0],dbxref:this.MSA.gs.DR?.[t]?.join("; ")}}getNames(){return Object.keys(this.MSA.seqdata)}getStructures(){let t=/PDB; +(\S+) +(\S); ([0-9]+)-([0-9]+)/,r=this.MSA.gs.DR??{},n={};for(let[o,i]of Object.entries(r))for(let a of i){let s=t.exec(a);s&&(n[o]??=[]).push({pdb:s[1].toLowerCase(),chain:s[2],startPos:+s[3],endPos:+s[4]})}return n}getTree(){let t=this.MSA.gf.NH?.[0];return t?za(gi(t)):super.getTree()}get seqConsensus(){return this.MSA.gc.seq_cons}get secondaryStructureConsensus(){return this.MSA.gc.SS_cons}get tracks(){return[{id:"seqConsensus",name:"Sequence consensus",data:this.seqConsensus,customColorScheme:{}},{id:"secondaryStruct",name:"Secondary-structure",data:this.secondaryStructureConsensus,customColorScheme:{"<":"lightblue","(":"lightblue","[":"lightblue","{":"lightblue",">":"pink",")":"pink","]":"pink","}":"pink"}}]}}});function kh(e,t=0,r){return r==="stockholm"?new Io(e,t):r==="a3m"?new Yn(e):r==="fasta"?new bo(e):r==="emf"?new Eo(e):r==="clustal"?new xo(e):Nc(e)?new Io(e,t):Yn.sniff(e)?new Yn(e):e.startsWith(">")?new bo(e):e.startsWith("SEQ")?new Eo(e):new xo(e)}function Dh(e){return e.replaceAll(/[.-]/g,"")}var EQ=d(()=>{Ih();Sh();vh();Th();_h();Bh();Qh();Ih();Sh();vh();Th();_h()});function L6(e){try{return decodeURIComponent(e)}catch{return e}}function F6(e){return e?Object.fromEntries(e.split(";").map(t=>t.trim()).filter(t=>!!t).map(t=>{let r=t.indexOf("="),n=(r===-1?t:t.slice(0,r)).trim(),o=r===-1?void 0:t.slice(r+1);return[n,o?o.split(",").map(i=>L6(i).trim()).join(" "):void 0]}).filter(([t])=>t!=="")):{}}function Rf(e){return e?e.split(`
+`).map(t=>t.trim()).filter(t=>!!t&&!t.startsWith("#")).map(t=>{let r=t.split("	"),[n,o,i,a,s,c,l,u]=r,A=r[8];return{seq_id:n??"",source:o??"",type:i??"",start:Number(a)||0,end:Number(s)||0,score:Number(c)||0,strand:l??".",phase:u??".",...F6(A)}}):[]}var bQ=d(()=>{});function O6({type:e,strand:t}){let r=t==="+"?1:t==="-"?-1:void 0;return P6.has(e)?r:void 0}function Lf(e){let t=new Map;for(let n of e){let o=t.get(n.seq_id);o?o.push(n):t.set(n.seq_id,[n])}let r={};for(let[n,o]of t){let i=new Map,a=new Map;for(let c of o){let l=c.Name||c.ID||`${c.source}_${c.start}_${c.end}`,u=c.signature_desc||c.Name||l,A=c.Ontology_term||c.description||c.Note||u;a.has(l)||a.set(l,{name:u,description:A,accession:l,featureType:c.type});let m={start:c.start,end:c.end,strand:O6(c)},f=i.get(l);f?f.push(m):i.set(l,[m])}let s=[];for(let[c,l]of i){let u=a.get(c);s.push({signature:{entry:u},locations:l})}r[n]={matches:s,xref:[{id:n}]}}return r}var P6,IQ=d(()=>{P6=new Set(["gene","pseudogene","mRNA","transcript","primary_transcript","ncRNA","tRNA","rRNA","snRNA","snoRNA","miRNA","lnc_RNA"])});var wQ=d(()=>{});var SQ=d(()=>{bQ();IQ();wQ()});var Nh=d(()=>{aQ();bh();EQ();SQ()});async function V6({seq:e,onProgress:t,onJobId:r,programs:n,model:o,signal:i}){let a=await xh(`${Rh}/iprscan5/run`,{method:"POST",body:new URLSearchParams({email:"colin.diesh@gmail.com",sequence:e,programs:n.join(",")}),signal:i});r?.(a),await Y6({jobId:a,onProgress:t,signal:i}),await $6({jobId:a,model:o,onProgress:t,signal:i})}function j6(e,t){return _f(`${Rh}/iprscan5/result/${e}/json`,{signal:t})}async function Y6({onProgress:e,jobId:t,signal:r}){let n=`${Rh}/iprscan5/status/${t}`,o=360;try{let i=!1;for(let a=0;a<o&&!i;a++){for(let c=0;c<10;c++)await tQ(1e3,r),e({msg:`Checking status ${10-c}`,url:n});let s=(await xh(n,{signal:r})).trim();if(s==="FINISHED")i=!0;else if(s==="FAILURE"||s==="ERROR"||s==="NOT_FOUND")throw new Error(`InterProScan job ${t} ended with status: ${s}`)}if(!i)throw new Error(`InterProScan job ${t} did not finish after ${o} status checks`)}finally{e()}}async function BQ({algorithm:e,seq:t,programs:r,onJobId:n,onProgress:o,model:i,signal:a}){try{if(o({msg:`Launching ${e} MSA`}),e==="interproscan")await V6({seq:t,onJobId:n,onProgress:o,programs:r,model:i,signal:a});else throw new Error("unknown algorithm")}catch(s){if(yo(s))(0,Rc.getSession)(i).notify("Cancelled InterProScan query","info");else throw s}finally{o()}}async function $6({jobId:e,model:t,onProgress:r,signal:n}){try{r({msg:`Downloading results of ${e} (for larger sequences this can be slow, click status to download and upload in the manual tab)`,url:`https://www.ebi.ac.uk/Tools/services/rest/iprscan5/result/${e}/json`});let o=await j6(e,n);t.setDomains(Object.fromEntries(o.results.map(i=>[i.xref[0]?.id,i]).filter(i=>i[0]!==void 0))),(0,Rc.getSession)(t).notify(`Loaded interproscan ${e} results`,"success")}catch(o){yo(o)?(0,Rc.getSession)(t).notify("Cancelled InterProScan query","info"):(console.error(o),(0,Rc.getSession)(t).notifyError(`${o}`,o))}finally{r()}}var Rc,Rh,vQ=d(()=>{Rc=p(Be(),1);kf();Rh="https://www.ebi.ac.uk/Tools/services/rest"});var _Q={};bt(_Q,{default:()=>J6});var Pe,TQ,QQ,ir,MQ,q6,J6,kQ=d(()=>{Pe=p(k(),1),TQ=p(Ye(),1),QQ=p(Be(),1),ir=p(V(),1),MQ=p($(),1);Nh();vQ();q6=(0,MQ.observer)(function({handleClose:e,model:t}){let[r,n]=(0,Pe.useState)([{name:"NCBIfam",description:"NCBI RefSeq FAMs including TIGRFAMs",category:"Families, domains, sites & repeats",checked:!0},{name:"SFLD",description:"Structure function linkage database",category:"Families, domains, sites & repeats",checked:!0},{name:"Phobius",checked:!0,description:"A combined transmembrane topology and signal peptide predictor",category:"Other sequence features"},{name:"SignalP",checked:!0,category:"Other sequence features"},{name:"SignalP_EUK",category:"Other category",checked:!0},{name:"SignalP_GRAM_POSITIVE",category:"Other category",checked:!0},{name:"SignalP_GRAM_NEGATIVE",checked:!0,category:"Other category"},{name:"SuperFamily",category:"Structural domains",checked:!0},{name:"Panther",category:"Families, domains, sites & repeats",checked:!0},{name:"Gene3d",category:"Structural domains",checked:!0},{name:"HAMAP",category:"Families, domains, sites & repeats",checked:!0},{name:"PrositeProfiles",category:"Families, domains, sites & repeats",checked:!0},{name:"PrositePatterns",category:"Families, domains, sites & repeats",checked:!0},{name:"Coils",category:"Other sequence features",checked:!0},{name:"SMART",category:"Families, domains, sites & repeats",checked:!0},{name:"CDD",description:"Conserved Domains Database",category:"Families, domains, sites & repeats",checked:!0},{name:"PRINTS",category:"Families, domains, sites & repeats",checked:!0},{name:"PfamA",category:"Families, domains, sites & repeats",checked:!0},{name:"MobiDBLite",checked:!0,category:"Other sequence features"},{name:"PIRSF",checked:!0,category:"Other category"},{name:"TMHMM",checked:!0,category:"Other sequence features"},{name:"AntiFam",checked:!0,category:"Other category"},{name:"FunFam",checked:!0,category:"Other category"},{name:"PIRSR",checked:!0,category:"Families, domains, sites & repeats"}]),o=r.filter(s=>s.checked).map(s=>s.name),[i,a]=(0,Pe.useState)(!1);return Pe.default.createElement(TQ.Dialog,{maxWidth:"xl",title:"Query InterProScan API for domains",onClose:()=>{e()},open:!0},Pe.default.createElement(ir.DialogContent,null,Pe.default.createElement(ir.Typography,null,"This will run InterProScan via the InterProScan API on all rows of the current MSA"),Pe.default.createElement(ir.Button,{onClick:()=>{a(!i)}},i?"Hide":"Show"," advanced options"),i?Pe.default.createElement("div",null,Pe.default.createElement(ir.Typography,null,"Select algorithms for InterProScan to run"),Pe.default.createElement("div",null,Pe.default.createElement(ir.Button,{variant:"contained",color:"secondary",onClick:()=>{n(r.map(s=>({...s,checked:!1})))}},"Select none"),Pe.default.createElement(ir.Button,{variant:"contained",color:"primary",onClick:()=>{n(r.map(s=>({...s,checked:!0})))}},"Select all")),Pe.default.createElement("table",null,Pe.default.createElement("tbody",null,r.toSorted((s,c)=>s.category.localeCompare(c.category)).map(({name:s,checked:c,category:l})=>Pe.default.createElement("tr",{key:s},Pe.default.createElement("td",null,Pe.default.createElement("input",{type:"checkbox",key:s,checked:c,onChange:()=>{n(r.map(u=>u.name===s?{...u,checked:!u.checked}:u))}})),Pe.default.createElement("td",null,s),Pe.default.createElement("td",null,l)))))):null),Pe.default.createElement(ir.DialogActions,null,Pe.default.createElement(ir.Button,{variant:"contained",color:"secondary",onClick:()=>{e()}},"Cancel"),Pe.default.createElement(ir.Button,{variant:"contained",color:"primary",onClick:()=>{let s=new AbortController;(async()=>{try{let{rows:c}=t;if(c.length>140)throw new Error("Too many sequences, please run InterProScan offline");await BQ({algorithm:"interproscan",programs:o,seq:c.map(l=>[l[0],Dh(l[1])]).filter(l=>!!l[1]).map(l=>`>${l[0]}
 ${l[1]}`).join(`
-`),onProgress:l=>{t.setStatus(l?{...l,onCancel:()=>{s.abort()}}:void 0)},model:t,signal:s.signal})}catch(c){console.error(c),(0,wb.getSession)(t).notifyError(`${c}`,c)}finally{t.setStatus()}})(),e()}},"Send sequences to InterProScan")))}),QL=SL});function Qb({model:e}){let{showDomains:t,actuallyShowDomains:r,subFeatureRows:n,noDomains:o}=e;return[{label:"Open domains...",icon:sl,onClick:()=>{e.queueDialog(i=>[ML,{handleClose:i,model:e}])}},{label:"Query InterProScan for domains...",icon:Fw,onClick:()=>{e.queueDialog(i=>[_L,{handleClose:i,model:e}])}},{label:`Show domains${o?" (no domains loaded)":""}`,disabled:o,icon:jw,checked:r?t:!1,type:"checkbox",onClick:()=>{e.setShowDomains(!t)}},{label:`Use sub-row layout${o?" (no domains loaded)":""}`,disabled:o,checked:r?n:!1,icon:Gw,type:"checkbox",onClick:()=>{e.setSubFeatureRows(!n)}},{label:`Filter domains${o?" (no domains loaded)":""}`,icon:Nw,disabled:o,onClick:()=>{e.queueDialog(i=>[vL,{onClose:i,model:e}])}}]}var gl,vL,ML,_L,vb=p(()=>{gl=f(M(),1);Lw();jd();Pw();Uw();qw();vL=(0,gl.lazy)(()=>Promise.resolve().then(()=>(Yw(),Vw))),ML=(0,gl.lazy)(()=>Promise.resolve().then(()=>(Zw(),Xw))),_L=(0,gl.lazy)(()=>Promise.resolve().then(()=>(Sb(),Bb)))});var TL,sm,Mb=p(()=>{TL={50:"#ffebee",100:"#ffcdd2",200:"#ef9a9a",300:"#e57373",400:"#ef5350",500:"#f44336",600:"#e53935",700:"#d32f2f",800:"#c62828",900:"#b71c1c",A100:"#ff8a80",A200:"#ff5252",A400:"#ff1744",A700:"#d50000"},sm=TL});var kL,cm,_b=p(()=>{kL={50:"#e3f2fd",100:"#bbdefb",200:"#90caf9",300:"#64b5f6",400:"#42a5f5",500:"#2196f3",600:"#1e88e5",700:"#1976d2",800:"#1565c0",900:"#0d47a1",A100:"#82b1ff",A200:"#448aff",A400:"#2979ff",A700:"#2962ff"},cm=kL});var DL,lm,Tb=p(()=>{DL={50:"#e8f5e9",100:"#c8e6c9",200:"#a5d6a7",300:"#81c784",400:"#66bb6a",500:"#4caf50",600:"#43a047",700:"#388e3c",800:"#2e7d32",900:"#1b5e20",A100:"#b9f6ca",A200:"#69f0ae",A400:"#00e676",A700:"#00c853"},lm=DL});var NL,Am,kb=p(()=>{NL={50:"#fff3e0",100:"#ffe0b2",200:"#ffcc80",300:"#ffb74d",400:"#ffa726",500:"#ff9800",600:"#fb8c00",700:"#f57c00",800:"#ef6c00",900:"#e65100",A100:"#ffd180",A200:"#ffab40",A400:"#ff9100",A700:"#ff6d00"},Am=NL});var LL,Pn,Db=p(()=>{LL={50:"#fafafa",100:"#f5f5f5",200:"#eeeeee",300:"#e0e0e0",400:"#bdbdbd",500:"#9e9e9e",600:"#757575",700:"#616161",800:"#424242",900:"#212121",A100:"#f5f5f5",A200:"#eeeeee",A400:"#bdbdbd",A700:"#616161"},Pn=LL});var Nb=p(()=>{Mb();_b();Tb();kb();Db()});var Pb=V((R7,Fb)=>{"use strict";var RL=function(t){return FL(t)&&!PL(t)};function FL(e){return!!e&&typeof e=="object"}function PL(e){var t=Object.prototype.toString.call(e);return t==="[object RegExp]"||t==="[object Date]"||UL(e)}var OL=typeof Symbol=="function"&&Symbol.for,GL=OL?Symbol.for("react.element"):60103;function UL(e){return e.$$typeof===GL}function HL(e){return Array.isArray(e)?[]:{}}function Za(e,t){return t.clone!==!1&&t.isMergeableObject(e)?Oi(HL(e),e,t):e}function jL(e,t,r){return e.concat(t).map(function(n){return Za(n,r)})}function qL(e,t){if(!t.customMerge)return Oi;var r=t.customMerge(e);return typeof r=="function"?r:Oi}function JL(e){return Object.getOwnPropertySymbols?Object.getOwnPropertySymbols(e).filter(function(t){return Object.propertyIsEnumerable.call(e,t)}):[]}function Lb(e){return Object.keys(e).concat(JL(e))}function Rb(e,t){try{return t in e}catch{return!1}}function VL(e,t){return Rb(e,t)&&!(Object.hasOwnProperty.call(e,t)&&Object.propertyIsEnumerable.call(e,t))}function YL(e,t,r){var n={};return r.isMergeableObject(e)&&Lb(e).forEach(function(o){n[o]=Za(e[o],r)}),Lb(t).forEach(function(o){VL(e,o)||(Rb(e,o)&&r.isMergeableObject(t[o])?n[o]=qL(o,r)(e[o],t[o],r):n[o]=Za(t[o],r))}),n}function Oi(e,t,r){r=r||{},r.arrayMerge=r.arrayMerge||jL,r.isMergeableObject=r.isMergeableObject||RL,r.cloneUnlessOtherwiseSpecified=Za;var n=Array.isArray(t),o=Array.isArray(e),i=n===o;return i?n?r.arrayMerge(e,t,r):YL(e,t,r):Za(t,r)}Oi.all=function(t,r){if(!Array.isArray(t))throw new Error("first argument should be an array");return t.reduce(function(n,o){return Oi(n,o,r)},{})};var zL=Oi;Fb.exports=zL});function Ub(){return{palette:{...hl,mode:void 0},components:{MuiLink:{styleOverrides:{root:({theme:e})=>({color:e.palette.tertiary.main})}}}}}function lR(){return{...Ub(),name:"Default (from config)"}}function AR(){return{...Ub(),name:"Light (stock)"}}function uR(){return{name:"Dark (stock)",palette:{...hl,mode:"dark"},components:{MuiAppBar:{defaultProps:{enableColorOnDark:!0},styleOverrides:{root:({theme:e})=>e.palette.primary.main}}}}}function fR(){return{name:"Dark (minimal)",palette:{...hl,mode:"dark",primary:{main:Pn[700]},secondary:{main:Pn[800]},tertiary:_e.palette.augmentColor({color:{main:Pn[900]}})}}}function dR(){return{name:"Light (minimal)",palette:{...hl,primary:{main:Pn[900]},secondary:{main:Pn[800]},tertiary:_e.palette.augmentColor({color:{main:Pn[900]}})}}}var Gb,WL,_e,$L,KL,XL,Ob,P7,ZL,eR,tR,rR,nR,oR,iR,aR,sR,cR,hl,O7,Hb=p(()=>{Gb=f(O(),1);Nb();WL=f(Pb(),1),_e=(0,Gb.createTheme)(),$L=_e.palette.augmentColor({color:{main:"#0D233F"}}),KL=_e.palette.augmentColor({color:{main:"#721E63"}}),XL=_e.palette.augmentColor({color:{main:"#135560"}}),Ob=_e.palette.augmentColor({color:{main:"#FFB11D"}}),P7=_e.palette.augmentColor({color:{main:"#aaa"}}),ZL={A:_e.palette.augmentColor({color:lm}),C:_e.palette.augmentColor({color:cm}),G:_e.palette.augmentColor({color:Am}),T:_e.palette.augmentColor({color:sm})},eR=[null,_e.palette.augmentColor({color:{main:"#FF8080"}}),_e.palette.augmentColor({color:{main:"#80FF80"}}),_e.palette.augmentColor({color:{main:"#8080FF"}}),_e.palette.augmentColor({color:{main:"#8080FF"}}),_e.palette.augmentColor({color:{main:"#80FF80"}}),_e.palette.augmentColor({color:{main:"#FF8080"}})],tR=[null,_e.palette.augmentColor({color:{main:"#8f8f8f"}}),_e.palette.augmentColor({color:{main:"#adadad"}}),_e.palette.augmentColor({color:{main:"#d8d8d8"}}),_e.palette.augmentColor({color:{main:"#d8d8d8"}}),_e.palette.augmentColor({color:{main:"#adadad"}}),_e.palette.augmentColor({color:{main:"#8f8f8f"}})],rR="#e22",nR="#3e3",oR="#800080",iR="#808080",aR="#f00",sR="#00f",cR="#97b8c9",hl={primary:$L,secondary:KL,tertiary:XL,quaternary:Ob,highlight:Ob,stopCodon:rR,startCodon:nR,insertion:oR,deletion:iR,softclip:sR,hardclip:aR,bases:ZL,frames:tR,framesCDS:eR,skip:cR};O7={default:lR(),lightStock:AR(),lightMinimal:dR(),darkMinimal:fR(),darkStock:uR()}});var jb=p(()=>{});var qb=p(()=>{});var um=p(()=>{Hb();Dd();jb();qb()});function On({value:e}){let{classes:t}=mR(),r=/^https?:\/\//.exec(`${e}`);return(0,Cl.jsx)("div",{className:t.fieldValue,children:(0,Jb.isValidElement)(e)?e:r?(0,Cl.jsx)(Vb.Link,{href:`${e}`,children:`${e}`}):(0,Cl.jsx)(Tn,{html:ir(e)?JSON.stringify(e):String(e)})})}var Cl,Jb,Vb,mR,El=p(()=>{Cl=f(R(),1),Jb=f(M(),1),Vb=f(O(),1);um();Qn();Re();mR=Y()(e=>({fieldValue:{wordBreak:"break-word",maxHeight:300,fontSize:12,padding:e.spacing(.5),overflow:"auto"}}))});function Or({description:e,name:t,width:r,prefix:n=[]}){let{classes:o}=pR(),i=[...n,t].join(".");return e?(0,Il.jsx)(Yb.Tooltip,{title:e,placement:"left",children:(0,Il.jsx)("div",{className:Cc(o.fieldDescription,o.fieldName),children:i})}):(0,Il.jsx)("div",{className:o.fieldName,style:{width:r},children:i})}var Il,Yb,pR,es=p(()=>{Il=f(R(),1),Yb=f(O(),1);Re();pR=Y()(e=>({fieldDescription:{"&:hover":{background:e.palette.mode==="dark"?"#e65100":"yellow"}},fieldName:{wordBreak:"break-all",minWidth:90,borderBottom:"1px solid #0003",fontSize:12,background:e.palette.action.disabledBackground,marginRight:e.spacing(1),padding:e.spacing(.5)}}))});function dm({name:e,value:t,description:r,formatter:n,prefix:o=[]}){let{classes:i}=gR(),[a,s]=(0,zb.useState)(!1),c=t.length>fm,l=c&&!a?t.slice(0,fm):t;return t.length===1?ir(t[0])?(0,Mt.jsx)(Gr,{formatter:n,attributes:t[0],prefix:[...o,e]}):(0,Mt.jsxs)("div",{className:i.field,children:[(0,Mt.jsx)(Or,{prefix:o,description:r,name:e}),(0,Mt.jsx)(On,{value:n?n(t[0],e):t[0]})]}):t.every(A=>ir(A))?(0,Mt.jsx)(Mt.Fragment,{children:t.map((A,u)=>(0,Mt.jsx)(Gr,{formatter:n,attributes:A,prefix:[...o,`${e}-${u}`]},`${JSON.stringify(A)}-${u}`))}):(0,Mt.jsxs)("div",{className:i.field,children:[(0,Mt.jsx)(Or,{prefix:o,description:r,name:e}),l.map((A,u)=>(0,Mt.jsx)("div",{className:i.fieldSubvalue,children:(0,Mt.jsx)(On,{value:n?n(A,e):A})},`${JSON.stringify(A)}-${u}`)),c?(0,Mt.jsx)("button",{type:"button",onClick:()=>{s(A=>!A)},children:a?"Show less":`Showing ${fm} of ${t.length}. Show all...`}):null]})}var Mt,zb,fm,gR,Wb=p(()=>{Mt=f(R(),1),zb=f(M(),1);xl();El();es();Qn();Re();fm=100,gR=Y()(e=>({field:{display:"flex",flexWrap:"wrap"},fieldSubvalue:{wordBreak:"break-word",maxHeight:300,padding:e.spacing(.5),border:`1px solid ${e.palette.action.selected}`,boxSizing:"border-box",overflow:"auto"}}))});var Kb=V((ij,$b)=>{$b.exports=JBrowseExports["@mui/x-data-grid"]});function mm({children:e,style:t}){let{classes:r}=hR();return(0,Xb.jsx)("div",{className:r.flexContainer,style:t,children:e})}var Xb,hR,Zb=p(()=>{Xb=f(R(),1);Re();hR=Y()({flexContainer:{display:"flex",flexDirection:"column"}})});function pm({value:e,prefix:t,name:r}){let{classes:n}=CR(),[o,i]=(0,eB.useState)(!1),a=Object.keys(e[0]).sort(),s=new Set(a),c=Object.entries(e).map(([u,m])=>{let{id:d,...g}=m;return{id:u,identifier:d,...g}});for(let u of e)for(let m of Object.keys(u))s.add(m);let l;s.has("id")?(s.delete("id"),l=["identifier",...s]):l=[...s];let A=l.map(u=>iy(c.map(m=>m[u])));return s.size<a.length+5?(0,gr.jsxs)("div",{className:n.margin,children:[(0,gr.jsx)(Or,{prefix:t,name:r}),(0,gr.jsx)(Gi.FormControlLabel,{control:(0,gr.jsx)(Gi.Checkbox,{checked:o,onChange:u=>{i(u.target.checked)}}),label:(0,gr.jsx)(Gi.Typography,{variant:"body2",children:"Show options"})}),(0,gr.jsx)(mm,{children:(0,gr.jsx)(tB.DataGrid,{disableRowSelectionOnClick:!0,rows:c,rowHeight:20,columnHeaderHeight:35,hideFooter:c.length<25,showToolbar:o,columns:l.map((u,m)=>({field:u,width:A[m],renderCell:({value:d})=>(0,gr.jsx)("div",{className:n.cell,children:(0,gr.jsx)(Tn,{html:bd(d||"")})})}))})})]}):null}var gr,eB,Gi,tB,CR,rB=p(()=>{gr=f(R(),1),eB=f(M(),1),Gi=f(O(),1),tB=f(Kb(),1);es();Zb();um();Qn();Re();CR=Y()(e=>({margin:{marginBottom:e.spacing(4)},cell:{whiteSpace:"nowrap",overflow:"hidden",textOverflow:"ellipsis"}}))});function gm({name:e,value:t,description:r,prefix:n,width:o,formatter:i}){let{classes:a}=ER();return t!=null?(0,ts.jsxs)("div",{className:a.field,children:[(0,ts.jsx)(Or,{prefix:n,description:r,name:e,width:o}),(0,ts.jsx)(On,{value:i?i(t,e):t})]}):null}var ts,ER,nB=p(()=>{ts=f(R(),1);El();es();Re();ER=Y()({field:{display:"flex",flexWrap:"wrap"}})});function hm({value:e,prefix:t,name:r}){let{classes:n}=IR(),{uri:o,baseUri:i=""}=e,a;try{a=new URL(o,i).href}catch{a=o}return(0,rs.jsxs)("div",{className:n.field,children:[(0,rs.jsx)(Or,{prefix:t,name:r}),(0,rs.jsx)(On,{value:a})]})}var rs,IR,oB=p(()=>{rs=f(R(),1);El();es();Re();IR=Y()({field:{display:"flex",flexWrap:"wrap"}})});function iB(e,t){return Math.ceil(Bd(e.map(r=>yd([...t,r[0]].join("."),12))))+10}function aB(e,t={}){let r=t;for(let n of e)ir(r)&&(r=r[n]);return typeof r=="string"?r:ir(r)&&typeof r.Description=="string"?r.Description:void 0}var sB=p(()=>{Qn()});function Gr(e){let{attributes:t,omit:r=[],omitSingleLevel:n=[],descriptions:o,formatter:i,hideUris:a,prefix:s=[]}=e,c=new Set([...r,...yR,...n]),{__jbrowsefmt:l,...A}=t,u=Object.entries({...A,...l}).filter(([d,g])=>g!=null&&!c.has(d)),m=iB(u,s);return(0,un.jsx)(un.Fragment,{children:u.map(([d,g])=>{let C=aB([...s,d],o);if(Array.isArray(g))return g.length>1&&g.every(y=>ir(y))?(0,un.jsx)(pm,{name:d,prefix:s,value:g},d):(0,un.jsx)(dm,{name:d,value:g,formatter:i,description:C,prefix:s},d);if(ir(g)){let{omitSingleLevel:y,...I}=e;return Hc(g)?a?null:(0,un.jsx)(hm,{name:d,prefix:s,value:g},d):(0,un.jsx)(Gr,{...I,formatter:i,attributes:g,descriptions:o,prefix:[...s,d]},d)}else return(0,un.jsx)(gm,{name:d,formatter:i,value:g,description:C,prefix:s,width:Math.min(m,xR)},d)})})}var un,xR,yR,xl=p(()=>{un=f(R(),1);Wb();rB();nB();oB();sB();Qn();xR=170,yR=["__jbrowsefmt","length","position","subfeatures","uniqueId","exonFrames","parentId","thickStart","thickEnd","_lineHash"]});var cB,lB,AB=p(()=>{"use client";Gt();cB=f(R(),1),lB=(0,Ee.createSvgIcon)((0,cB.jsx)("path",{d:"M16.59 8.59 12 13.17 7.41 8.59 6 10l6 6 6-6z"}),"ExpandMore")});function wo({children:e,title:t,defaultExpanded:r=!0}){let{classes:n}=wR();return(0,yo.jsxs)(Gn.Accordion,{defaultExpanded:r,children:[(0,yo.jsx)(Gn.AccordionSummary,{expandIcon:(0,yo.jsx)(lB,{className:n.icon}),children:(0,yo.jsx)(Gn.Typography,{variant:"button",children:t})}),(0,yo.jsx)(Gn.AccordionDetails,{className:n.expansionPanelDetails,children:e})]})}var yo,Gn,wR,Cm=p(()=>{yo=f(R(),1);AB();Gn=f(O(),1);Re();wR=Y()(e=>({expansionPanelDetails:{display:"block",padding:e.spacing(1)},icon:{color:e.palette.tertiary.contrastText||"#fff"}}))});function bo({checked:e,label:t,disabled:r,onChange:n}){return yl.default.createElement("div",null,yl.default.createElement(wl.FormControlLabel,{control:yl.default.createElement(wl.Checkbox,{disabled:r,checked:e,onChange:()=>{n()}}),label:t}))}var yl,wl,Em=p(()=>{yl=f(M(),1),wl=f(O(),1)});function ns({str:e}){let{classes:t}=bR(),[r,n]=(0,hr.useState)(!1),[o,i]=(0,hr.useState)(!1),[a,s]=(0,hr.useState)(!1),c=A=>A.replaceAll("-","").replaceAll(".",""),l=e.map(([A,u])=>[A,o?u:c(u)]).filter(([,A])=>a||!!A).map(([A,u])=>`>${A}
-${u}`).join(`
-`);return hr.default.createElement(hr.default.Fragment,null,hr.default.createElement(bl.Button,{color:"primary",variant:"contained",onClick:()=>{Ma(l),n(!0),setTimeout(()=>{n(!1)},500)}},r?"Copied!":"Copy to clipboard"),hr.default.createElement(bo,{label:"Show gaps",checked:o,onChange:()=>{i(!o)}}),hr.default.createElement(bo,{label:"Show empty",checked:a,onChange:()=>{s(!a)}}),hr.default.createElement(bl.TextField,{variant:"outlined",multiline:!0,className:t.dialogContent,minRows:5,maxRows:10,fullWidth:!0,value:l,slotProps:{input:{readOnly:!0,className:t.textAreaFont}}}))}var hr,bl,bR,Im=p(()=>{hr=f(M(),1);Re();bl=f(O(),1);Em();Zu();bR=Y()({textAreaFont:{fontFamily:"Courier New",wordWrap:"break-word"},dialogContent:{background:"lightgrey",margin:4,minWidth:"80em"}})});var mB={};dt(mB,{default:()=>SR});var Ui,uB,fB,dB,BR,SR,pB=p(()=>{Ui=f(M(),1);xl();Cm();uB=f(Ne(),1),fB=f(O(),1),dB=f(H(),1);Im();BR=(0,dB.observer)(function({model:e,onClose:t}){let{header:r}=e;return Ui.default.createElement(uB.Dialog,{onClose:()=>{t()},open:!0,title:"Metadata",maxWidth:"xl"},Ui.default.createElement(fB.DialogContent,null,Ui.default.createElement(Gr,{attributes:r}),Ui.default.createElement(wo,{title:"sequence"},Ui.default.createElement(ns,{str:e.rows}))))}),SR=BR});var hB={};dt(hB,{default:()=>gB});function gB({model:e,onClose:t}){let[r,n]=(0,Se.useState)(!0),[o,i]=(0,Se.useState)(!0),[a,s]=(0,Se.useState)("viewport"),[c,l]=(0,Se.useState)(),A=(0,ye.useTheme)(),{totalWidth:u,totalHeight:m,treeAreaWidth:d,turnedOnTracks:g,totalTrackAreaHeight:C}=e,y=g.length>0,I=u+d,E=m+(o?C:0),b=a==="entire"&&(I>1e4||E>1e4);return Se.default.createElement(Bl.Dialog,{onClose:()=>{t()},open:!0,title:"Export SVG"},Se.default.createElement(ye.DialogContent,null,c?Se.default.createElement(Bl.ErrorMessage,{error:c}):null,Se.default.createElement(ye.Typography,null,"Settings:"),Se.default.createElement(bo,{label:"Include minimap?",disabled:a==="entire",checked:r,onChange:()=>{n(!r)}}),y?Se.default.createElement(bo,{label:"Include tracks?",checked:o,onChange:()=>{i(!o)}}):null,Se.default.createElement("div",null,Se.default.createElement(ye.FormControl,null,Se.default.createElement(ye.FormLabel,null,"Export type"),Se.default.createElement(ye.RadioGroup,{value:a,onChange:x=>{let{value:w}=x.target;(w==="entire"||w==="viewport")&&s(w)}},Se.default.createElement(ye.FormControlLabel,{value:"entire",control:Se.default.createElement(ye.Radio,null),label:"Entire MSA"}),Se.default.createElement(ye.FormControlLabel,{value:"viewport",control:Se.default.createElement(ye.Radio,null),label:"Current viewport only"})))),b?Se.default.createElement(ye.Alert,{severity:"warning",style:{marginTop:8}},"The entire MSA is very large (",Math.round(I),"x",Math.round(E)," pixels). Export may be slow or fail."):null),Se.default.createElement(ye.DialogActions,null,Se.default.createElement(ye.Button,{variant:"contained",color:"primary",onClick:()=>{e.exportSVG({theme:A,includeMinimap:a==="entire"?!1:r,includeTracks:y&&o,exportType:a}).then(()=>{t()}).catch(x=>{console.error(x),l(x)})}},"Submit"),Se.default.createElement(ye.Button,{variant:"contained",color:"secondary",onClick:()=>{t()}},"Cancel")))}var Se,Bl,ye,CB=p(()=>{Se=f(M(),1),Bl=f(Ne(),1),ye=f(O(),1);Em()});var Hi,EB,QR,vR,MR,IB,xB=p(()=>{Hi=f(M(),1);Li();Sw();jd();_w();kw();EB=f(H(),1);vb();QR=(0,Hi.lazy)(()=>Promise.resolve().then(()=>(pB(),mB))),vR=(0,Hi.lazy)(()=>Promise.resolve().then(()=>(CB(),hB))),MR=(0,EB.observer)(({model:e})=>Hi.default.createElement(Pr,{"data-testid":"file_menu",tooltip:"File",menuItems:[{label:"Return to import form",icon:sl,onClick:()=>{e.reset()}},{label:"Metadata",icon:Bw,onClick:()=>{e.queueDialog(t=>[QR,{model:e,onClose:t}])}},{label:"Domain settings",type:"subMenu",subMenu:Qb({model:e})},{label:"Export SVG",icon:Tw,onClick:()=>{e.queueDialog(t=>[vR,{onClose:t,model:e}])}}],anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"}},Hi.default.createElement(Mw,null))),IB=MR});var Sl,Ql,yB,_R,wB,bB=p(()=>{Sl=f(M(),1),Ql=f(O(),1),yB=f(H(),1),_R=(0,yB.observer)(function({model:t}){let{hideGaps:r,allowedGappyness:n}=t;return r?Sl.default.createElement("div",{style:{display:"flex",alignItems:"center",gap:8}},Sl.default.createElement(Ql.Typography,{style:{whiteSpace:"nowrap"}},"Hide columns w/ >",n,"% gaps"),Sl.default.createElement(Ql.Slider,{style:{width:100},min:1,max:100,value:n,onChange:(o,i)=>{t.setAllowedGappyness(i)}})):null}),wB=_R});var vl,BB,SB,TR,kR,QB,vB=p(()=>{vl=f(M(),1);Re();BB=f(O(),1),SB=f(H(),1),TR=Y()({container:{display:"flex",overflow:"hidden",margin:"auto",marginLeft:10},nameFirst:{overflow:"hidden",textOverflow:"ellipsis",whiteSpace:"nowrap",minWidth:0},nameRest:{whiteSpace:"nowrap",flexShrink:0}}),kR=(0,SB.observer)(function({model:e}){let{mouseOverRowName:t,mouseCol:r}=e,{classes:n}=TR();if(!t||r===void 0)return null;let o=Math.floor(t.length/2),i=e.visibleColToSeqPosOneBased(t,r),a=e.visibleColToRowLetter(t,r);return vl.default.createElement(BB.Typography,{component:"div",className:n.container,title:t},vl.default.createElement("span",{className:n.nameFirst},t.slice(0,o)),vl.default.createElement("span",{className:n.nameRest},t.slice(o),":",i," (",a,")"))}),QB=kR});var os,MB,Ml,_B,DR,NR,TB,kB=p(()=>{os=f(M(),1),MB=f(Ne(),1);Re();Ml=f(O(),1),_B=f(H(),1),DR=Y()({margin:{margin:"auto",marginLeft:10}}),NR=(0,_B.observer)(({model:e})=>{let{status:t}=e,{classes:r}=DR();return t?os.default.createElement(Ml.Typography,{className:r.margin},os.default.createElement(MB.LoadingEllipses,{message:t.msg,component:"span"})," ",t.url?os.default.createElement("a",{href:t.url,target:"_blank",rel:"noreferrer"},"(status)"):null," ",t.onCancel?os.default.createElement(Ml.Button,{size:"small",onClick:()=>t.onCancel?.()},"Cancel"):null):null}),TB=NR});var DB,NB,LB=p(()=>{"use client";me();DB=f(R(),1),NB=(0,j.createSvgIcon)((0,DB.jsx)("path",{d:"M3 17v2h6v-2zM3 5v2h10V5zm10 16v-2h8v-2h-8v-2h-2v6zM7 9v2H3v2h4v2h2V9zm14 4v-2H11v2zm-6-4h2V7h4V5h-4V3h-2z"}),"Tune")});function RB(e){let{drawMsaLetters:t,hideGaps:r,bgColor:n,showColumnStats:o}=e;return[{label:"Show column statistics on hover",type:"checkbox",checked:o,onClick:()=>{e.setShowColumnStats(!o)}},{label:"Draw letters",type:"checkbox",checked:t,onClick:()=>{e.setDrawMsaLetters(!t)}},{label:"Color letters instead of background of tiles",type:"checkbox",checked:!n,onClick:()=>{e.setBgColor(!n)}},{label:"Enable hiding gappy columns?",type:"checkbox",checked:r,onClick:()=>{e.setHideGaps(!r)}}]}function FB(e){let{drawTree:t,showBranchLen:r,labelsAlignRight:n,drawNodeBubbles:o,drawLabels:i}=e;return[{label:"Show branch length",type:"checkbox",checked:r,onClick:()=>{e.setShowBranchLen(!r)}},{label:"Show tree",type:"checkbox",checked:t,onClick:()=>{e.setDrawTree(!t)}},{label:"Draw clickable bubbles on tree branches",type:"checkbox",checked:o,onClick:()=>{e.setDrawNodeBubbles(!o)}},{label:"Tree labels align right",type:"checkbox",checked:n,onClick:()=>{e.setLabelsAlignRight(!n)}},{label:"Draw labels",type:"checkbox",checked:i,onClick:()=>{e.setDrawLabels(!i)}}]}var xm=p(()=>{});var ym,PB,LR,OB,GB=p(()=>{ym=f(M(),1);Li();LB();PB=f(H(),1);xm();LR=(0,PB.observer)(function({model:e}){return ym.default.createElement(Pr,{"data-testid":"msa_settings_menu",tooltip:"Alignment settings",closeAfterItemClick:!1,anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"},menuItems:RB(e)},ym.default.createElement(NB,null))}),OB=LR});var wm,_l,UB,RR,HB,jB=p(()=>{wm=f(M(),1),_l=f(O(),1),UB=f(H(),1),RR=(0,UB.observer)(function({model:e}){let{currentAlignment:t,alignmentNames:r}=e,n=new Map;return r.length>0?wm.default.createElement(_l.TextField,{select:!0,variant:"outlined",value:t,size:"small",onChange:o=>{e.setCurrentAlignment(+o.target.value),e.setScrollX(0),e.setScrollY(0)}},r.map((o,i)=>{let a=n.get(o)??0;return n.set(o,a+1),wm.default.createElement(_l.MenuItem,{key:a===0?o:`${o}\0${a}`,value:i},o)})):null}),HB=RR});var qB,JB,VB=p(()=>{"use client";me();qB=f(R(),1),JB=(0,j.createSvgIcon)((0,qB.jsx)("path",{d:"M22 11V3h-7v3H9V3H2v8h7V8h2v10h4v3h7v-8h-7v3h-2V8h2v3z"}),"AccountTree")});var bm,YB,FR,zB,WB=p(()=>{bm=f(M(),1);Li();VB();YB=f(H(),1);xm();FR=(0,YB.observer)(function({model:e}){let{rows:t}=e;return bm.default.createElement(Pr,{"data-testid":"tree_settings_menu",tooltip:"Tree settings",closeAfterItemClick:!1,anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"},menuItems:[...FB(e),...t.length>=2?[{label:"Advanced",type:"subMenu",subMenu:[{label:"Calculate neighbor joining tree (BLOSUM62)",onClick:()=>{try{e.calculateNeighborJoiningTreeFromMSA()}catch(r){console.error("Failed to calculate NJ tree:",r),e.setError(r)}}}]}]:[]]},bm.default.createElement(JB,null))}),zB=FR});var $B,KB,XB=p(()=>{"use client";me();$B=f(R(),1),KB=(0,j.createSvgIcon)((0,$B.jsx)("path",{d:"M13 1.07V9h7c0-4.08-3.05-7.44-7-7.93M4 15c0 4.42 3.58 8 8 8s8-3.58 8-8v-4H4zm7-13.93C7.05 1.56 4 4.92 4 9h7z"}),"Mouse")});var Bm,ZB,e1=p(()=>{"use client";me();Bm=f(R(),1),ZB=(0,j.createSvgIcon)([(0,Bm.jsx)("path",{d:"M15.5 14h-.79l-.28-.27C15.41 12.59 16 11.11 16 9.5 16 5.91 13.09 3 9.5 3S3 5.91 3 9.5 5.91 16 9.5 16c1.61 0 3.09-.59 4.23-1.57l.27.28v.79l5 4.99L20.49 19zm-6 0C7.01 14 5 11.99 5 9.5S7.01 5 9.5 5 14 7.01 14 9.5 11.99 14 9.5 14"},"0"),(0,Bm.jsx)("path",{d:"M12 10h-2v2H9v-2H7V9h2V7h1v2h2z"},"1")],"ZoomIn")});var t1,r1,n1=p(()=>{"use client";me();t1=f(R(),1),r1=(0,j.createSvgIcon)((0,t1.jsx)("path",{d:"M15.5 14h-.79l-.28-.27C15.41 12.59 16 11.11 16 9.5 16 5.91 13.09 3 9.5 3S3 5.91 3 9.5 5.91 16 9.5 16c1.61 0 3.09-.59 4.23-1.57l.27.28v.79l5 4.99L20.49 19zm-6 0C7.01 14 5 11.99 5 9.5S7.01 5 9.5 5 14 7.01 14 9.5 11.99 14 9.5 14M7 9h5v1H7z"}),"ZoomOut")});var Cr,Un,o1,PR,i1,a1=p(()=>{Cr=f(M(),1);XB();e1();n1();Un=f(O(),1),o1=f(H(),1),PR=(0,o1.observer)(function({model:t}){return Cr.default.createElement(Cr.default.Fragment,null,Cr.default.createElement(Un.Tooltip,{title:"Zoom in"},Cr.default.createElement(Un.IconButton,{"aria-label":"Zoom in",onClick:()=>{t.zoomIn()}},Cr.default.createElement(ZB,null))),Cr.default.createElement(Un.Tooltip,{title:"Zoom out"},Cr.default.createElement(Un.IconButton,{"aria-label":"Zoom out",onClick:()=>{t.zoomOut()}},Cr.default.createElement(r1,null))),Cr.default.createElement(Un.ToggleButton,{value:"scrollZoom",selected:t.scrollZoom,"aria-label":"Toggle scroll-to-zoom",title:"Toggle scroll-to-zoom (zoom on plain mouse wheel; ctrl+wheel always zooms)",size:"small",sx:{border:"none"},onChange:()=>{t.setScrollZoom(!t.scrollZoom)}},Cr.default.createElement(KB,null)))}),i1=PR});var s1,c1,l1=p(()=>{"use client";me();s1=f(R(),1),c1=(0,j.createSvgIcon)((0,s1.jsx)("path",{d:"M12 8c1.1 0 2-.9 2-2s-.9-2-2-2-2 .9-2 2 .9 2 2 2m0 2c-1.1 0-2 .9-2 2s.9 2 2 2 2-.9 2-2-.9-2-2-2m0 6c-1.1 0-2 .9-2 2s.9 2 2 2 2-.9 2-2-.9-2-2-2"}),"MoreVert")});var A1,u1,f1=p(()=>{"use client";me();A1=f(R(),1),u1=(0,j.createSvgIcon)((0,A1.jsx)("path",{d:"M12 5V2L8 6l4 4V7c3.31 0 6 2.69 6 6 0 2.97-2.17 5.43-5 5.91v2.02c3.95-.49 7-3.85 7-7.93 0-4.42-3.58-8-8-8m-6 8c0-1.65.67-3.15 1.76-4.24L6.34 7.34C4.9 8.79 4 10.79 4 13c0 4.08 3.05 7.44 7 7.93v-2.02c-2.83-.48-5-2.94-5-5.91"}),"RestartAlt")});var Sm,d1,OR,m1,p1=p(()=>{Sm=f(M(),1);Li();l1();f1();d1=f(H(),1),OR=(0,d1.observer)(function({model:e}){return Sm.default.createElement(Pr,{tooltip:"Fit / zoom options",menuItems:[{label:"Fit both vertically/horizontally",onClick:()=>{e.fit()}},{label:"Fit vertically",onClick:()=>{e.fitVertically()}},{label:"Fit horizontally",onClick:()=>{e.fitHorizontally()}},{label:"Reset zoom to default",icon:u1,onClick:()=>{e.resetZoom()}}]},Sm.default.createElement(c1,null))}),m1=OR});var g1,h1=p(()=>{g1="5.6.1"});var I1={};dt(I1,{default:()=>E1});function E1({onClose:e}){return Ve.default.createElement(C1.Dialog,{open:!0,title:"About",onClose:()=>{e()}},Ve.default.createElement(_t.DialogContent,null,Ve.default.createElement(_t.Typography,null,"MSAView ",g1," (",Ve.default.createElement(_t.Link,{href:"https://github.com/gmod/react-msaview"},"Github"),")"),Ve.default.createElement("ul",null,Ve.default.createElement("li",null,Ve.default.createElement(_t.Typography,null,"We use some color schemes from the"," ",Ve.default.createElement(_t.Link,{href:"https://github.com/biotite-dev/biotite"},"biotite")," ","project, and their license is reproduced"," ",Ve.default.createElement(_t.Link,{href:"https://github.com/biotite-dev/biotite/blob/master/LICENSE.rst"},"here"))),Ve.default.createElement("li",null,Ve.default.createElement(_t.Typography,null,"See this page for some information on jalview colorings"," ",Ve.default.createElement(_t.Link,{href:"https://www.jalview.org/help/html/colourSchemes/"},"here"))),Ve.default.createElement("li",null,Ve.default.createElement(_t.Typography,null,"See this page for some info on the clustal, cinema, maeditor, and lesk color schemes"," ",Ve.default.createElement(_t.Link,{href:"http://www.bioinformatics.nl/~berndb/aacolour.html"},"here"))),Ve.default.createElement("li",null,Ve.default.createElement(_t.Typography,null,"See this paper about the flower color scheme"," ",Ve.default.createElement(_t.Link,{href:"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245768/"},"here"))))))}var Ve,C1,_t,x1=p(()=>{Ve=f(M(),1),C1=f(Ne(),1),_t=f(O(),1);h1()});function HR(){return De.default.createElement("div",{style:{flex:1}})}var De,Tl,y1,GR,UR,w1,b1=p(()=>{De=f(M(),1);fC();pC();Tl=f(O(),1),y1=f(H(),1);ww();xB();bB();vB();kB();GB();jB();WB();a1();p1();GR=(0,De.lazy)(()=>Promise.resolve().then(()=>(x1(),I1))),UR=(0,y1.observer)(function({model:e}){let[t,{height:r}]=tf();return(0,De.useEffect)(()=>{e.setHeaderHeight(r??0)},[e,r]),De.default.createElement("div",{ref:t,style:{display:"flex"}},De.default.createElement(IB,{model:e}),De.default.createElement(yw,{model:e}),De.default.createElement(zB,{model:e}),De.default.createElement(OB,{model:e}),De.default.createElement(i1,{model:e}),De.default.createElement(m1,{model:e}),De.default.createElement(wB,{model:e}),De.default.createElement("div",{style:{paddingLeft:20,margin:"auto"}},De.default.createElement(HB,{model:e})),De.default.createElement(QB,{model:e}),De.default.createElement(HR,null),De.default.createElement(TB,{model:e}),De.default.createElement(Tl.Tooltip,{title:"About"},De.default.createElement(Tl.IconButton,{"aria-label":"About",onClick:()=>{e.queueDialog(n=>[GR,{onClose:n}])}},De.default.createElement(mC,null))))});w1=UR});var Ur,B1,jR,S1,Q1=p(()=>{Ur=f(M(),1),B1=f(H(),1);zA();Vs();jR=(0,B1.observer)(function({model:e}){let[t,r]=(0,Ur.useState)(!1),{minimapHeight:n}=e,{unit:o,s:i,w:a,polygonHeight:s,polygonPoints:c}=ks(e),l="rgba(66, 119, 127, 0.3)",{startDrag:A}=yn("x",(0,Ur.useCallback)((u,m)=>{e.setScrollX(m-u/o)},[e,o]));return Ur.default.createElement("div",{style:{position:"relative",height:n,width:"100%"}},Ur.default.createElement("div",{style:{height:12,boxSizing:"border-box",border:"1px solid #555"}}),Ur.default.createElement("div",{style:{position:"absolute",top:0,left:Math.max(0,i),background:t?"rgba(66,119,127,0.6)":l,cursor:"pointer",height:12,width:a,zIndex:100},onMouseOver:()=>{r(!0)},onMouseOut:()=>{r(!1)},onMouseDown:u=>{A(u,e.scrollX)}}),Ur.default.createElement("svg",{height:s,style:{width:"100%"}},Ur.default.createElement("polygon",{fill:l,points:c})))}),S1=jR});var v1,M1,_1=p(()=>{"use client";me();v1=f(R(),1),M1=(0,j.createSvgIcon)((0,v1.jsx)("path",{d:"m12 8-6 6 1.41 1.41L12 10.83l4.59 4.58L18 14z"}),"ExpandLess")});var T1,kl,Qm=p(()=>{"use client";me();T1=f(R(),1),kl=(0,j.createSvgIcon)((0,T1.jsx)("path",{d:"M16.59 8.59 12 13.17 7.41 8.59 6 10l6 6 6-6z"}),"ExpandMore")});var Er,ji,k1,qR,D1,N1=p(()=>{Er=f(M(),1);_1();Qm();ji=f(O(),1),k1=f(H(),1),qR=(0,k1.observer)(function({model:e}){let[t,r]=(0,Er.useState)(!0),{actuallyShowDomains:n,visibleDomainTypes:o,fillPalette:i}=e,a=t?M1:kl;return n&&o.length>0?Er.default.createElement(ji.Paper,{elevation:3,style:{position:"absolute",top:4,right:4,zIndex:100,maxWidth:260,maxHeight:"60%",display:"flex",flexDirection:"column",opacity:.95}},Er.default.createElement("div",{style:{display:"flex",alignItems:"center",justifyContent:"flex-end",padding:"2px 4px 2px 8px"}},Er.default.createElement(ji.IconButton,{size:"small",onClick:()=>{r(!t)}},Er.default.createElement(a,{fontSize:"small"}))),t?Er.default.createElement("div",{style:{overflow:"auto",padding:"0 8px 6px"}},o.map(({accession:s,name:c})=>Er.default.createElement("div",{key:s,style:{display:"flex",alignItems:"center",gap:6},title:s},Er.default.createElement("div",{style:{width:12,height:12,flexShrink:0,background:i[s]}}),Er.default.createElement(ji.Typography,{variant:"caption",noWrap:!0},c)))):null):null}),D1=qR});function vm(){return Dl.default.createElement("div",{style:{position:"absolute",left:"50%",top:"50%"}},Dl.default.createElement(Nl.CircularProgress,null),Dl.default.createElement(Nl.Typography,null,"Loading..."))}var Dl,Nl,L1=p(()=>{Dl=f(M(),1),Nl=f(O(),1)});var zt,R1,Mm,JR,F1,P1=p(()=>{zt=f(M(),1),R1=f(H(),1),Mm=e=>`${Math.round(e*100)}%`,JR=(0,R1.observer)(function({model:e}){let t=e.mouseOverColumnStats;if(!t)return null;let{col:r,total:n,conservation:o,propertyConservation:i,consensusLetter:a,consensusFraction:s,gapFraction:c,distribution:l}=t,A=l.slice(0,6);return zt.default.createElement("div",null,zt.default.createElement("b",null,"Column ",r+1)," (",n," seqs)",zt.default.createElement("br",null),"Consensus: ",a||"-"," (",Mm(s),")",zt.default.createElement("br",null),"Conservation: ",o.toFixed(2),i===void 0?null:zt.default.createElement(zt.default.Fragment,null,zt.default.createElement("br",null),"Property conservation: ",i.toFixed(2)),zt.default.createElement("br",null),"Gaps: ",Mm(c),A.length>0?zt.default.createElement(zt.default.Fragment,null,zt.default.createElement("br",null),A.map(([u,m])=>zt.default.createElement("span",{key:u,style:{marginRight:8}},u," ",Mm(m/n)))):null)}),F1=JR});function ar(e,t){let r=(0,Ll.useRef)(null);return(0,Ll.useEffect)(()=>{let n=r.current?.getContext("2d");return n?(0,O1.autorun)(()=>{e(n)}):void 0},t),r}var Ll,O1,Bo=p(()=>{Ll=f(M(),1),O1=f(Vo(),1)});function Rl(e){let t=(0,U1.useTheme)(),r=(0,G1.useMemo)(()=>Aa(e,t),[e,t]);return{theme:t,contrastScheme:r}}var G1,U1,_m=p(()=>{G1=f(M(),1),U1=f(O(),1);xn()});function H1(e,t,r,n,o,i){let{left:a,top:s}=t.getBoundingClientRect();return{col:Math.floor((e.clientX-a+r)/o),row:Math.floor((e.clientY-s+n)/i)}}var Nt,Tm,j1,VR,q1,J1=p(()=>{Nt=f(M(),1),Tm=f(Ne(),1),j1=f(H(),1);P1();XA();Au();Bo();_m();VR=(0,j1.observer)(function({model:e,offsetX:t,offsetY:r}){let{colWidth:n,rowHeight:o,scrollY:i,scrollX:a,colorScheme:s,blockSize:c,mouseClickCol:l,mouseClickRow:A,highResScaleFactor:u}=e,{theme:m,contrastScheme:d}=Rl(s),g=ar(x=>{x.resetTransform(),x.clearRect(0,0,c*u,c*u),e.actuallyShowDomains&&Fs({ctx:x,offsetX:t,offsetY:r,model:e}),Us({ctx:x,theme:m,offsetX:t,offsetY:r,contrastScheme:d,model:e})},[e,t,r,m,c,u,d]),[C,y]=(0,Nt.useState)(),{hoveredInsertion:I,mouseOverDomains:E,showColumnStats:b}=e;return Nt.default.createElement(Nt.default.Fragment,null,Nt.default.createElement("canvas",{ref:g,onMouseMove:x=>{if(g.current){let{col:w,row:Q}=H1(x,g.current,t,r,n,o);w>=0&&w<e.numColumns&&Q>=0&&Q<e.numRows?e.setMousePos(w,Q):e.setMousePos(void 0,void 0);let S=e.hoveredInsertion||e.mouseOverDomains.length>0||e.showColumnStats&&!!e.mouseOverColumnStats;y(S?{x:x.clientX,y:x.clientY}:void 0)}},onClick:x=>{if(g.current){let{col:w,row:Q}=H1(x,g.current,t,r,n,o);w===l&&Q===A?e.setMouseClickPos(void 0,void 0):e.setMouseClickPos(w,Q)}},onMouseLeave:()=>{e.setMousePos(),y(void 0)},width:c*u,height:c*u,style:{position:"absolute",top:i+r,left:a+t,width:c,height:c}}),I&&C?Nt.default.createElement(Tm.BaseTooltip,{clientPoint:{x:C.x,y:C.y+15}},"Insertion (",I.letters.length,e.sequenceType==="amino"?"aa":"bp","):"," ",I.letters.length>20?`${I.letters.slice(0,20)}...`:I.letters):null,!I&&C&&(E.length>0||b)?Nt.default.createElement(Tm.BaseTooltip,{clientPoint:{x:C.x,y:C.y+15}},E.map(x=>Nt.default.createElement("div",{key:`${x.accession}-${x.start}-${x.end}`},Nt.default.createElement("b",null,x.name)," (",x.accession,") ",x.start,"-",x.end,x.description?Nt.default.createElement(Nt.default.Fragment,null,Nt.default.createElement("br",null),x.description):null)),b?Nt.default.createElement(F1,{model:e}):null):null)}),q1=VR});var Hr,V1,YR,Y1,z1=p(()=>{Hr=f(M(),1),V1=f(H(),1);L1();J1();Ec();YR=(0,V1.observer)(function({model:e}){let{MSA:t,verticalScrollbarWidth:r,msaFilehandle:n,height:o,msaAreaWidth:i,blocks2d:a,scrollZoom:s}=e,c=(0,Hr.useRef)(null),l=(0,Hr.useCallback)(g=>{e.doScrollX(g)},[e]),A=(0,Hr.useCallback)(g=>{e.doScrollY(g)},[e]),u=(0,Hr.useCallback)((g,C,y)=>{e.zoomToPos(g,C,y)},[e]),{onMouseDown:m,onMouseUp:d}=fi({ref:c,onScrollX:l,onScrollY:A,onZoom:u,scrollZoom:s});return Hr.default.createElement("div",{ref:c,onMouseDown:m,onMouseUp:d,onMouseLeave:g=>{g.preventDefault()},style:{position:"relative",height:o,width:i-r,overflow:"hidden"}},!t&&!n?null:t?a.map(([g,C])=>Hr.default.createElement(q1,{key:`${g}_${C}`,model:e,offsetX:g,offsetY:C})):Hr.default.createElement(vm,null))}),Y1=YR});var Fl,km,W1,Dm=p(()=>{Fl="rgba(0,128,255,0.3)",km="rgba(255,165,0,0.2)",W1="rgba(255,165,0,0.15)"});function $R(e){let t=[...e].sort((n,o)=>n-o),r=[];for(let n of t){let o=r.at(-1);o&&n===o.end+1?o.end=n:r.push({start:n,end:n})}return r}function X1({ctx:e,model:t}){let{mouseCol:r,colWidth:n,msaAreaWidth:o,verticalScrollbarWidth:i,height:a,rowHeight:s,scrollX:c,scrollY:l,mouseRow:A,mouseClickRow:u,mouseClickCol:m,relativeTo:d,hoveredTreeNode:g,highlightedColumns:C,highResScaleFactor:y}=t,I=o-i;if(e.resetTransform(),e.clearRect(0,0,I*y,a*y),e.scale(y,y),d){let E=t.rowNamesSet.get(d);E!==void 0&&(e.fillStyle=Fl,e.fillRect(0,E*s+l,I,s))}if(g){e.fillStyle=W1;for(let E of g.descendantNames){let b=t.rowNamesSet.get(E);b!==void 0&&e.fillRect(0,b*s+l,I,s)}}if(C?.length){e.lineWidth=2;for(let{start:E,end:b}of $R(C)){let x=E*n+c,w=(b-E+1)*n;e.fillStyle=zR,e.fillRect(x,0,w,a),e.strokeStyle=WR,e.strokeRect(x,0,w,a)}}r!==void 0&&(e.fillStyle=$1,e.fillRect(r*n+c,0,n,a)),A!==void 0&&(e.fillStyle=$1,e.fillRect(0,A*s+l,I,s)),m!==void 0&&(e.fillStyle=K1,e.fillRect(m*n+c,0,n,a)),u!==void 0&&(e.fillStyle=K1,e.fillRect(0,u*s+l,I,s))}var $1,K1,zR,WR,Z1=p(()=>{Dm();$1="rgba(0,0,0,0.15)",K1="rgba(128,128,0,0.2)",zR="rgba(255,140,0,0.28)",WR="rgba(210,90,0,0.95)"});var eS,tS,rS,KR,nS,oS=p(()=>{eS=f(M(),1),tS=f(Pt(),1),rS=f(H(),1);Z1();Bo();KR=(0,rS.observer)(function({model:e}){let{height:t,msaAreaWidth:r,verticalScrollbarWidth:n,highResScaleFactor:o}=e,i=r-n,a=ar(s=>{(0,tS.isAlive)(e)&&X1({ctx:s,model:e})},[e]);return eS.default.createElement("canvas",{ref:a,id:"mouseover",width:i*o,height:t*o,style:{position:"absolute",top:0,left:0,width:i,height:t,zIndex:1e3,pointerEvents:"none"}})}),nS=KR});var is,iS,XR,aS,sS=p(()=>{is=f(M(),1),iS=f(H(),1);N1();z1();oS();XR=(0,iS.observer)(function({model:e}){return is.default.createElement("div",{style:{position:"relative"}},is.default.createElement(Y1,{model:e}),is.default.createElement(nS,{model:e}),is.default.createElement(D1,{model:e}))}),aS=XR});var as,qi,cS,ZR,lS,AS=p(()=>{as=f(M(),1),qi=f(O(),1),cS=f(H(),1),ZR=(0,cS.observer)(function({node:e,model:t,onClose:r}){return as.default.createElement(qi.Menu,{anchorReference:"anchorPosition",anchorPosition:{left:e.x,top:e.y},transitionDuration:0,keepMounted:!0,open:!!e,onClose:r},as.default.createElement(qi.MenuItem,{dense:!0,disabled:!0},e.name),as.default.createElement(qi.MenuItem,{dense:!0,onClick:()=>{t.toggleCollapsed(e.id),r()}},t.collapsed.includes(e.id)?"Expand this node":"Collapse this node"),as.default.createElement(qi.MenuItem,{dense:!0,onClick:()=>{t.showOnly===e.id?t.setShowOnly(void 0):t.setShowOnly(e.id),r()}},t.showOnly===e.id?"Disable show only this node":"Show only this node"))}),lS=ZR});var mS={};dt(mS,{default:()=>tF});var jr,uS,fS,dS,eF,tF,pS=p(()=>{jr=f(M(),1);xl();Cm();uS=f(Ne(),1),fS=f(O(),1),dS=f(H(),1);Im();eF=(0,dS.observer)(function({info:e,model:t,nodeName:r,onClose:n}){let{treeMetadata:o,rows:i}=t,a=o[r],s=i.find(c=>c[0]===r);return jr.default.createElement(uS.Dialog,{onClose:()=>{n()},open:!0,title:"Tree node info",maxWidth:"xl"},jr.default.createElement(fS.DialogContent,null,jr.default.createElement(wo,{title:"Attributes"},jr.default.createElement(Gr,{attributes:{nodeName:r,...e}})),jr.default.createElement(wo,{title:"Sequence"},s?jr.default.createElement(ns,{str:[s]}):jr.default.createElement("div",null,"Sequence not found")),a?jr.default.createElement(wo,{title:"Extra metadata"},jr.default.createElement(Gr,{attributes:a})):null))}),tF=eF});var fn,Hn,gS,rF,nF,hS,CS=p(()=>{fn=f(M(),1),Hn=f(O(),1),gS=f(H(),1),rF=(0,fn.lazy)(()=>Promise.resolve().then(()=>(pS(),mS))),nF=(0,gS.observer)(function({node:e,onClose:t,model:r}){let{collapsed:n}=r,{name:o,id:i}=e,a=n.includes(i);return fn.default.createElement(Hn.Menu,{anchorReference:"anchorPosition",anchorPosition:{top:e.y,left:e.x},transitionDuration:0,keepMounted:!0,open:!!e,onClose:t},fn.default.createElement(Hn.MenuItem,{dense:!0,disabled:!0},o),fn.default.createElement(Hn.MenuItem,{dense:!0,onClick:()=>{r.queueDialog(s=>[rF,{info:r.getRowData(o),model:r,nodeName:o,onClose:s}]),t()}},"More info..."),fn.default.createElement(Hn.MenuItem,{dense:!0,onClick:()=>{r.toggleCollapsed(i),t()}},a?"Expand subtree":"Collapse subtree"),fn.default.createElement(Hn.MenuItem,{dense:!0,onClick:()=>{r.drawRelativeTo(e.name),t()}},"Indicate differences from this row"),r.relativeTo?fn.default.createElement(Hn.MenuItem,{dense:!0,onClick:()=>{r.drawRelativeTo(void 0),t()}},"Clear reference row"):null)}),hS=nF});var ss,ES=p(()=>{ss=class{constructor(t=1/0,r=Float64Array,n=Uint32Array){let o=t!==1/0;this.ids=o?new n(t):[],this.values=o?new r(t):[],this.capacity=t,this.length=0}clear(){this.length=0}push(t,r){if(this.length===this.capacity)throw new RangeError("Queue is at capacity.");let n=this.length++;for(;n>0;){let o=n-1>>1,i=this.values[o];if(r>=i)break;this.ids[n]=this.ids[o],this.values[n]=i,n=o}this.ids[n]=t,this.values[n]=r}pop(){if(this.length===0)return;let t=this.ids,r=this.values,n=t[0],o=--this.length;if(o>0){let i=t[o],a=r[o],s=0,c=o>>1;for(;s<c;){let l=(s<<1)+1,A=l+1,u=l+(+(A<o)&+(r[A]<r[l]));if(r[u]>=a)break;t[s]=t[u],r[s]=r[u],s=u}t[s]=i,r[s]=a}return n}peek(){return this.length>0?this.ids[0]:void 0}peekValue(){return this.length>0?this.values[0]:void 0}shrink(){Array.isArray(this.ids)&&(this.ids.length=this.length),Array.isArray(this.values)&&(this.values.length=this.length)}}});function oF(e,t){let r=0,n=t.length-1;for(;r<n;){let o=r+n>>1;t[o]>e?n=o:r=o+1}return t[r]}function iF(e,t,r,n,o,i){let a=[n,o];for(;a.length;){let s=a.pop()||0,c=a.pop()||0;if(s-c<=i&&Math.floor(c/i)>=Math.floor(s/i))continue;let l=e[c],A=e[c+s>>1],u=e[s],m=l>A!=l>u?l:A<l!=A<u?A:u,d=c-1,g=s+1;for(;;){do d++;while(e[d]<m);do g--;while(e[g]>m);if(d>=g)break;aF(e,t,r,d,g)}a.push(c,g,g+1,s)}}function aF(e,t,r,n,o){let i=e[n];e[n]=e[o],e[o]=i;let a=4*n,s=4*o,c=t[a],l=t[a+1],A=t[a+2],u=t[a+3];t[a]=t[s],t[a+1]=t[s+1],t[a+2]=t[s+2],t[a+3]=t[s+3],t[s]=c,t[s+1]=l,t[s+2]=A,t[s+3]=u;let m=r[n];r[n]=r[o],r[o]=m}function sF(e,t){let r=e^t,n=65535^r,o=65535^(e|t),i=e&(t^65535),a=r|n>>1,s=r>>1^r,c=o^(o>>1^n&i>>1),l=i^(r&o>>1^i>>1);return r=a&a>>2^s&s>>2,n=a&s>>2^s&(a^s)>>2,o=c^(a&c>>2^s&l>>2),i=l^(s&c>>2^(a^s)&l>>2),a=r&r>>4^n&n>>4,s=r&n>>4^n&(r^n)>>4,c=o^(r&o>>4^n&i>>4),l=i^(n&o>>4^(r^n)&i>>4),o=c^(a&c>>8^s&l>>8),i=l^(s&c>>8^(a^s)&l>>8),o^=o>>1,i^=i>>1,r=e^t,n=i|65535^(r|o),r=(r|r<<8)&16711935,r=(r|r<<4)&252645135,r=(r|r<<2)&858993459,r=(r|r<<1)&1431655765,n=(n|n<<8)&16711935,n=(n|n<<4)&252645135,n=(n|n<<2)&858993459,n=(n|n<<1)&1431655765,((n<<1|r)>>>0)-2147483648}var IS,Nm,cs,xS=p(()=>{ES();IS=[Int8Array,Uint8Array,Uint8ClampedArray,Int16Array,Uint16Array,Int32Array,Uint32Array,Float32Array,Float64Array],Nm=3,cs=class e{static from(t,r=0){if(r%8!==0)throw new Error("byteOffset must be 8-byte aligned.");if(!t||t.byteLength===void 0||"buffer"in t)throw new Error("Data must be an instance of ArrayBuffer or SharedArrayBuffer.");let[n,o]=new Uint8Array(t,r+0,2);if(n!==251)throw new Error("Data does not appear to be in a Flatbush format.");let i=o>>4;if(i!==Nm)throw new Error(`Got v${i} data when expected v${Nm}.`);let a=IS[o&15];if(!a)throw new Error("Unrecognized array type.");let[s]=new Uint16Array(t,r+2,1),[c]=new Uint32Array(t,r+4,1);return new e(c,s,a,void 0,t,r)}constructor(t,r=16,n=Float64Array,o=ArrayBuffer,i,a=0){if(t===void 0)throw new Error("Missing required argument: numItems.");if(isNaN(t)||t<=0)throw new Error(`Unexpected numItems value: ${t}.`);this.numItems=+t,this.nodeSize=Math.min(Math.max(+r,2),65535),this.byteOffset=a;let s=t,c=s;this._levelBounds=[s*4];do s=Math.ceil(s/this.nodeSize),c+=s,this._levelBounds.push(c*4);while(s!==1);this.ArrayType=n,this.IndexArrayType=c<16384?Uint16Array:Uint32Array;let l=IS.indexOf(n),A=c*4*n.BYTES_PER_ELEMENT;if(l<0)throw new Error(`Unexpected typed array class: ${n}.`);let u=n,m=this.IndexArrayType;if(i)this.data=i,this._boxes=new u(i,a+8,c*4),this._indices=new m(i,a+8+A,c),this._pos=c*4,this.minX=this._boxes[this._pos-4],this.minY=this._boxes[this._pos-3],this.maxX=this._boxes[this._pos-2],this.maxY=this._boxes[this._pos-1];else{let d=this.data=new o(8+A+c*this.IndexArrayType.BYTES_PER_ELEMENT);this._boxes=new u(d,8,c*4),this._indices=new m(d,8+A,c),this._pos=0,this.minX=1/0,this.minY=1/0,this.maxX=-1/0,this.maxY=-1/0,new Uint8Array(d,0,2).set([251,(Nm<<4)+l]),new Uint16Array(d,2,1)[0]=r,new Uint32Array(d,4,1)[0]=t}this._queue=new ss}add(t,r,n=t,o=r){let i=this._pos,a=i>>2,s=this._boxes;return this._indices[a]=a,s[i]=t,s[i+1]=r,s[i+2]=n,s[i+3]=o,this._pos=i+4,t<this.minX&&(this.minX=t),r<this.minY&&(this.minY=r),n>this.maxX&&(this.maxX=n),o>this.maxY&&(this.maxY=o),a}finish(){if(this._pos>>2!==this.numItems)throw new Error(`Added ${this._pos>>2} items when expected ${this.numItems}.`);let t=this._boxes;if(this.numItems<=this.nodeSize){t[this._pos++]=this.minX,t[this._pos++]=this.minY,t[this._pos++]=this.maxX,t[this._pos++]=this.maxY;return}let{numItems:r,minX:n,minY:o,nodeSize:i,_indices:a,_levelBounds:s}=this,c=this.maxX-n||1,l=this.maxY-o||1,A=new Int32Array(r),u=65535,m=u/c,d=u/l;for(let C=0,y=0;C<r;C++){let I=t[y++],E=t[y++],b=t[y++],x=t[y++],w=m*((I+b)/2-n)|0,Q=d*((E+x)/2-o)|0;A[C]=sF(w,Q)}iF(A,t,a,0,r-1,i);let g=r*4;for(let C=0,y=0;C<s.length-1;C++){let I=s[C];for(;y<I;){let E=y,b=t[y++],x=t[y++],w=t[y++],Q=t[y++];for(let S=1;S<i&&y<I;S++)b=Math.min(b,t[y++]),x=Math.min(x,t[y++]),w=Math.max(w,t[y++]),Q=Math.max(Q,t[y++]);a[g>>2]=E,t[g++]=b,t[g++]=x,t[g++]=w,t[g++]=Q}}this._pos=g}search(t,r,n,o,i){if(this._pos!==this._boxes.length)throw new Error("Data not yet indexed - call index.finish().");let{_boxes:a,_levelBounds:s,_indices:c,nodeSize:l}=this,A=this.numItems*4,u=a.length-4,m=s.length-1,d=[],g=[],C=!1;for(;u!==void 0;){let y=Math.min(u+l*4,s[m]),I=u>=A;if(C)this._collectContained(u,y,m,A,g,i);else for(let E=u;E<y;E+=4){let b=a[E];if(n<b)continue;let x=a[E+1];if(o<x)continue;let w=a[E+2];if(t>w)continue;let Q=a[E+3];if(r>Q)continue;let S=c[E>>2]|0;if(I){let k=+(t<=b&&r<=x&&n>=w&&o>=Q);d.push(S|k,m-1)}else(i===void 0||i(S,b,x,w,Q))&&g.push(S)}m=d.pop(),u=d.pop(),u!==void 0&&(C=(u&1)===1,u&=-2)}return g}_collectContained(t,r,n,o,i,a){let s=this._boxes,c=this._indices,l=t;for(let u=n;u>0;u--)l=c[l>>2];let A=Math.min(l+(r-t)*this.nodeSize**n,o);if(a===void 0)for(;l<A;l+=4)i.push(c[l>>2]|0);else for(;l<A;l+=4){let u=c[l>>2]|0;a(u,s[l],s[l+1],s[l+2],s[l+3])&&i.push(u)}}neighbors(t,r,n=1/0,o=1/0,i){if(this._pos!==this._boxes.length)throw new Error("Data not yet indexed - call index.finish().");let{_boxes:a,_levelBounds:s,_indices:c,_queue:l,nodeSize:A}=this,u=this.numItems*4,m=A*4,d=[],g=o*o,C=n===1,y=g;for(l.push(a.length-4<<1,0);l.length;){let I=l.ids[0];if(I&1){if(l.pop(),d.push(I>>1),d.length===n)break;continue}l.pop();let E=I>>1,b=E<u,x=Math.min(E+m,oF(E,s));for(let w=E;w<x;w+=4){let Q=a[w],S=a[w+1],k=a[w+2],N=a[w+3],_=Math.max(Math.max(Q-t,t-k),0),v=Math.max(Math.max(S-r,r-N),0),L=_*_+v*v;if(L>y)continue;let U=c[w>>2]|0;b?(i===void 0||i(U))&&(l.push(U<<1|1,L),C&&L<y&&(y=L)):l.push(U<<1,L)}}return l.clear(),d}}});var Pl,yS=p(()=>{xS();Pl=class{flatbush=null;entries=[];clear(){this.flatbush=null,this.entries=[]}insert(t){this.entries.push(t)}finish(){if(this.entries.length===0)this.flatbush=null;else{this.flatbush=new cs(this.entries.length);for(let t of this.entries)this.flatbush.add(t.minX,t.minY,t.maxX,t.maxY);this.flatbush.finish()}}search(t){return this.flatbush?.search(t.minX,t.minY,t.maxX,t.maxY).map(r=>this.entries[r])??[]}}});var et,wS,bS,cF,lF,BS,SS=p(()=>{et=f(M(),1);Re();wS=f(O(),1),bS=f(H(),1);AS();CS();yS();Js();Bo();cF=Y()(e=>({tooltip:{position:"fixed",pointerEvents:"none",zIndex:1e4,backgroundColor:e.palette.grey[700],color:e.palette.common.white,padding:"4px 8px",borderRadius:4,fontSize:12,whiteSpace:"nowrap",maxWidth:300,overflow:"hidden",textOverflow:"ellipsis"}})),lF=(0,bS.observer)(function({model:e,offsetY:t}){let{classes:r}=cF(),n=(0,wS.useTheme)(),o=(0,et.useRef)(new Pl),i=(0,et.useRef)(null),[a,s]=(0,et.useState)(),[c,l]=(0,et.useState)(),[A,u]=(0,et.useState)(),[m,d]=(0,et.useState)(),{scrollY:g,treeAreaWidth:C,blockSize:y,highResScaleFactor:I}=e,E=C+ga,b=y,x=E*I,w=b*I,Q=ar(_=>{_.resetTransform(),_.clearRect(0,0,x,w),qs({ctx:_,model:e,offsetY:t,clickMap:o.current,theme:n})},[e,y,I,C,t,n]);(0,et.useEffect)(()=>{let _=i.current?.getContext("2d");if(_&&(_.resetTransform(),_.clearRect(0,0,C+ga,y),_.translate(0,-t),A)){let{minX:v,maxX:L,minY:U,maxY:W}=A;_.fillStyle="rgba(0,0,0,0.1)",_.fillRect(v,U,L-v,W-U)}},[A,t,y,C]);function S(_){let v=_.nativeEvent.offsetX,L=_.nativeEvent.offsetY,[U]=o.current.search({minX:v,maxX:v+1,minY:L+t,maxY:L+1+t});return U?.branch?{...U,x:_.clientX,y:_.clientY}:void 0}function k(_){let v=_.nativeEvent.offsetX,L=_.nativeEvent.offsetY,[U]=o.current.search({minX:v,maxX:v+1,minY:L+t,maxY:L+1+t});return U&&!U.branch?{...U,x:_.clientX,y:_.clientY}:void 0}let N={width:E,height:b,top:g+t,left:0,position:"absolute"};return et.default.createElement(et.default.Fragment,null,a?.id?et.default.createElement(lS,{node:a,model:e,onClose:()=>{s(void 0)}}):null,c?.id?et.default.createElement(hS,{node:c,model:e,onClose:()=>{l(void 0)}}):null,et.default.createElement("canvas",{width:x,height:w,style:N,onMouseMove:_=>{if(!Q.current)return;let v=k(_),L=S(_),U=v||L;if(Q.current.style.cursor=U?"pointer":"default",u(v),d(U?{name:U.name,x:_.clientX,y:_.clientY}:void 0),U){if(e.setHoveredTreeNode(U.id),v?.name){let W=e.rowNamesSet.get(v.name);W!==void 0&&e.setMousePos(void 0,W)}}else e.setHoveredTreeNode(void 0),e.setMousePos(void 0,void 0)},onClick:_=>{let{clientX:v,clientY:L}=_,U=S(_);U?.id&&s({x:v,y:L,id:U.id,name:U.name});let W=k(_);W?.id&&l({...W,x:v,y:L})},onMouseLeave:()=>{u(void 0),d(void 0),e.setHoveredTreeNode(void 0),e.setMousePos(void 0,void 0)},ref:Q}),et.default.createElement("canvas",{style:{...N,pointerEvents:"none",zIndex:100},width:E,height:b,ref:i}),m?et.default.createElement("div",{className:r.tooltip,style:{left:m.x+12,top:m.y+12}},m.name):null)}),BS=lF});var jn,QS,vS,AF,MS,_S=p(()=>{jn=f(M(),1),QS=f(Pt(),1),vS=f(H(),1);SS();Js();Bo();Ec();Dm();AF=(0,vS.observer)(function({model:e}){let t=(0,jn.useRef)(null),{treeWidth:r,height:n,blocksY:o,treeAreaWidth:i}=e,a=(0,jn.useCallback)(A=>{e.doScrollY(A)},[e]),{onMouseDown:s,onMouseUp:c}=fi({ref:t,onScrollY:a}),l=ar(A=>{if((0,QS.isAlive)(e)){let{relativeTo:u,leaves:m,rowHeight:d,hoveredTreeNode:g,treeAreaWidth:C,height:y,scrollY:I,mouseOverRowName:E}=e;A.resetTransform(),A.clearRect(0,0,C,y);let b=new Map(m.map(w=>[w.data.name,w])),x=w=>{let Q=b.get(w);Q&&A.fillRect(0,Q.x+I-d/2,C,d)};if(u&&(A.fillStyle=Fl,x(u)),g){A.fillStyle=km;for(let w of g.descendantNames)x(w)}E&&E!==u&&!g?.descendantNames.includes(E)&&(A.fillStyle=km,x(E))}},[e]);return jn.default.createElement("div",{ref:t,onMouseDown:s,onMouseUp:c,onMouseLeave:A=>{A.preventDefault()},style:{height:n,position:"relative",width:r+ga}},o.map(A=>jn.default.createElement(BS,{key:A,model:e,offsetY:A})),jn.default.createElement("canvas",{ref:l,width:i,height:n,style:{position:"absolute",top:0,left:0,width:i,height:n,zIndex:1e3,pointerEvents:"none"}}))}),MS=AF});var Lm,TS,uF,kS,DS=p(()=>{Lm=f(M(),1),TS=f(H(),1);_S();uF=(0,TS.observer)(function({model:e}){let{treeAreaWidth:t}=e;return Lm.default.createElement("div",{style:{overflow:"hidden",flexShrink:0,width:t}},Lm.default.createElement(MS,{model:e}))}),kS=uF});var NS,LS,fF,RS,FS=p(()=>{NS=f(M(),1),LS=f(H(),1),fF=(0,LS.observer)(({model:e})=>{let{treeAreaWidth:t}=e;return NS.default.createElement("div",{style:{flexShrink:0,width:t}})}),RS=fF});var ee,So,dF,mF,pF,gF,hF,CF,PS,OS=p(()=>{ee=f(M(),1),So=f(H(),1);Th();Su();sC();uC();b1();Q1();sS();DS();FS();dF=(0,So.observer)(function({model:e}){let{showHorizontalScrollbar:t}=e;return ee.default.createElement("div",{style:{display:"flex"}},ee.default.createElement(RS,{model:e}),t?ee.default.createElement(S1,{model:e}):null)}),mF=(0,So.observer)(function({model:e}){let{mouseCol:t,mouseClickCol:r,colWidth:n,scrollX:o,treeAreaWidth:i,resizeHandleWidth:a,totalTrackAreaHeight:s,msaAreaWidth:c,verticalScrollbarWidth:l}=e,A=i+a,u=c-l;return ee.default.createElement("div",{style:{position:"absolute",left:A,top:0,width:u,height:s,overflow:"hidden",pointerEvents:"none"}},t!==void 0?ee.default.createElement("div",{style:{position:"absolute",left:t*n+o,top:0,width:n,height:s,backgroundColor:"rgba(0,0,0,0.15)",zIndex:100}}):null,r!==void 0?ee.default.createElement("div",{style:{position:"absolute",left:r*n+o,top:0,width:n,height:s,backgroundColor:"rgba(128,128,0,0.2)",zIndex:100}}):null)}),pF=(0,So.observer)(function({model:e}){let{turnedOnTracks:t}=e;return t.length===0?null:ee.default.createElement("div",{style:{position:"relative"}},ee.default.createElement(mF,{model:e}),t.map(r=>ee.default.createElement(aC,{key:r.model.id,model:e,track:r})))}),gF=(0,So.observer)(function({model:e}){let{showVerticalScrollbar:t}=e;return ee.default.createElement("div",{style:{display:"flex"}},ee.default.createElement(kS,{model:e}),ee.default.createElement(kh,{model:e}),ee.default.createElement(aS,{model:e}),t?ee.default.createElement(AC,{model:e}):null)}),hF=(0,So.observer)(function({model:e}){return ee.default.createElement("div",{style:{position:"relative"}},ee.default.createElement(dF,{model:e}),ee.default.createElement(pF,{model:e}),ee.default.createElement(gF,{model:e}))}),CF=(0,So.observer)(function({model:e}){let{height:t,viewInitialized:r,DialogComponent:n,DialogProps:o}=e,i=_h();return(0,ee.useEffect)(()=>{e.setHighResScaleFactor(i)},[e,i]),ee.default.createElement("div",null,r?ee.default.createElement(ee.default.Fragment,null,ee.default.createElement("div",{style:{height:t,overflow:"hidden"}},ee.default.createElement(w1,{model:e}),ee.default.createElement(hF,{model:e})),ee.default.createElement(Dh,{model:e}),n?ee.default.createElement(ee.Suspense,{fallback:null},ee.default.createElement(n,{...o})):null):null)}),PS=CF});var GS,US,HS,jS=p(()=>{GS=`CLUSTAL O(1.2.3) multiple sequence alignment
+`),onProgress:l=>{t.setStatus(l?{...l,onCancel:()=>{s.abort()}}:void 0)},model:t,signal:s.signal})}catch(c){console.error(c),(0,QQ.getSession)(t).notifyError(`${c}`,c)}finally{t.setStatus()}})(),e()}},"Send sequences to InterProScan")))}),J6=q6});function DQ({model:e}){let{showDomains:t,actuallyShowDomains:r,subFeatureRows:n,noDomains:o}=e;return[{label:"Open domains...",icon:Tf,onClick:()=>{e.queueDialog(i=>[z6,{handleClose:i,model:e}])}},{label:"Query InterProScan for domains...",icon:VT,onClick:()=>{e.queueDialog(i=>[K6,{handleClose:i,model:e}])}},{label:`Show domains${o?" (no domains loaded)":""}`,disabled:o,icon:WT,checked:r?t:!1,type:"checkbox",onClick:()=>{e.setShowDomains(!t)}},{label:`Use sub-row layout${o?" (no domains loaded)":""}`,disabled:o,checked:r?n:!1,icon:$T,type:"checkbox",onClick:()=>{e.setSubFeatureRows(!n)}},{label:`Filter domains${o?" (no domains loaded)":""}`,icon:GT,disabled:o,onClick:()=>{e.queueDialog(i=>[W6,{onClose:i,model:e}])}}]}var Ff,W6,z6,K6,NQ=d(()=>{Ff=p(k(),1);UT();Ch();jT();qT();zT();W6=(0,Ff.lazy)(()=>Promise.resolve().then(()=>(ZT(),XT))),z6=(0,Ff.lazy)(()=>Promise.resolve().then(()=>(iQ(),oQ))),K6=(0,Ff.lazy)(()=>Promise.resolve().then(()=>(kQ(),_Q)))});var X6,Lh,RQ=d(()=>{X6={50:"#ffebee",100:"#ffcdd2",200:"#ef9a9a",300:"#e57373",400:"#ef5350",500:"#f44336",600:"#e53935",700:"#d32f2f",800:"#c62828",900:"#b71c1c",A100:"#ff8a80",A200:"#ff5252",A400:"#ff1744",A700:"#d50000"},Lh=X6});var Z6,Fh,LQ=d(()=>{Z6={50:"#e3f2fd",100:"#bbdefb",200:"#90caf9",300:"#64b5f6",400:"#42a5f5",500:"#2196f3",600:"#1e88e5",700:"#1976d2",800:"#1565c0",900:"#0d47a1",A100:"#82b1ff",A200:"#448aff",A400:"#2979ff",A700:"#2962ff"},Fh=Z6});var eG,Ph,FQ=d(()=>{eG={50:"#e8f5e9",100:"#c8e6c9",200:"#a5d6a7",300:"#81c784",400:"#66bb6a",500:"#4caf50",600:"#43a047",700:"#388e3c",800:"#2e7d32",900:"#1b5e20",A100:"#b9f6ca",A200:"#69f0ae",A400:"#00e676",A700:"#00c853"},Ph=eG});var tG,Oh,PQ=d(()=>{tG={50:"#fff3e0",100:"#ffe0b2",200:"#ffcc80",300:"#ffb74d",400:"#ffa726",500:"#ff9800",600:"#fb8c00",700:"#f57c00",800:"#ef6c00",900:"#e65100",A100:"#ffd180",A200:"#ffab40",A400:"#ff9100",A700:"#ff6d00"},Oh=tG});var rG,wo,OQ=d(()=>{rG={50:"#fafafa",100:"#f5f5f5",200:"#eeeeee",300:"#e0e0e0",400:"#bdbdbd",500:"#9e9e9e",600:"#757575",700:"#616161",800:"#424242",900:"#212121",A100:"#f5f5f5",A200:"#eeeeee",A400:"#bdbdbd",A700:"#616161"},wo=rG});var GQ=d(()=>{RQ();LQ();FQ();PQ();OQ()});var jQ=z((sie,VQ)=>{"use strict";var nG=function(t){return oG(t)&&!iG(t)};function oG(e){return!!e&&typeof e=="object"}function iG(e){var t=Object.prototype.toString.call(e);return t==="[object RegExp]"||t==="[object Date]"||cG(e)}var aG=typeof Symbol=="function"&&Symbol.for,sG=aG?Symbol.for("react.element"):60103;function cG(e){return e.$$typeof===sG}function lG(e){return Array.isArray(e)?[]:{}}function Lc(e,t){return t.clone!==!1&&t.isMergeableObject(e)?Za(lG(e),e,t):e}function uG(e,t,r){return e.concat(t).map(function(n){return Lc(n,r)})}function fG(e,t){if(!t.customMerge)return Za;var r=t.customMerge(e);return typeof r=="function"?r:Za}function AG(e){return Object.getOwnPropertySymbols?Object.getOwnPropertySymbols(e).filter(function(t){return Object.propertyIsEnumerable.call(e,t)}):[]}function UQ(e){return Object.keys(e).concat(AG(e))}function HQ(e,t){try{return t in e}catch{return!1}}function dG(e,t){return HQ(e,t)&&!(Object.hasOwnProperty.call(e,t)&&Object.propertyIsEnumerable.call(e,t))}function mG(e,t,r){var n={};return r.isMergeableObject(e)&&UQ(e).forEach(function(o){n[o]=Lc(e[o],r)}),UQ(t).forEach(function(o){dG(e,o)||(HQ(e,o)&&r.isMergeableObject(t[o])?n[o]=fG(o,r)(e[o],t[o],r):n[o]=Lc(t[o],r))}),n}function Za(e,t,r){r=r||{},r.arrayMerge=r.arrayMerge||uG,r.isMergeableObject=r.isMergeableObject||nG,r.cloneUnlessOtherwiseSpecified=Lc;var n=Array.isArray(t),o=Array.isArray(e),i=n===o;return i?n?r.arrayMerge(e,t,r):mG(e,t,r):Lc(t,r)}Za.all=function(t,r){if(!Array.isArray(t))throw new Error("first argument should be an array");return t.reduce(function(n,o){return Za(n,o,r)},{})};var pG=Za;VQ.exports=pG});function qQ(){return{palette:{...Pf,mode:void 0},components:{MuiLink:{styleOverrides:{root:({theme:e})=>({color:e.palette.tertiary.main})}}}}}function MG(){return{...qQ(),name:"Default (from config)"}}function _G(){return{...qQ(),name:"Light (stock)"}}function kG(){return{name:"Dark (stock)",palette:{...Pf,mode:"dark"},components:{MuiAppBar:{defaultProps:{enableColorOnDark:!0},styleOverrides:{root:({theme:e})=>e.palette.primary.main}}}}}function DG(){return{name:"Dark (minimal)",palette:{...Pf,mode:"dark",primary:{main:wo[700]},secondary:{main:wo[800]},tertiary:Oe.palette.augmentColor({color:{main:wo[900]}})}}}function NG(){return{name:"Light (minimal)",palette:{...Pf,primary:{main:wo[900]},secondary:{main:wo[800]},tertiary:Oe.palette.augmentColor({color:{main:wo[900]}})}}}var $Q,gG,Oe,hG,CG,yG,YQ,lie,xG,EG,bG,IG,wG,SG,BG,vG,TG,QG,Pf,uie,JQ=d(()=>{$Q=p(V(),1);GQ();gG=p(jQ(),1),Oe=(0,$Q.createTheme)(),hG=Oe.palette.augmentColor({color:{main:"#0D233F"}}),CG=Oe.palette.augmentColor({color:{main:"#721E63"}}),yG=Oe.palette.augmentColor({color:{main:"#135560"}}),YQ=Oe.palette.augmentColor({color:{main:"#FFB11D"}}),lie=Oe.palette.augmentColor({color:{main:"#aaa"}}),xG={A:Oe.palette.augmentColor({color:Ph}),C:Oe.palette.augmentColor({color:Fh}),G:Oe.palette.augmentColor({color:Oh}),T:Oe.palette.augmentColor({color:Lh})},EG=[null,Oe.palette.augmentColor({color:{main:"#FF8080"}}),Oe.palette.augmentColor({color:{main:"#80FF80"}}),Oe.palette.augmentColor({color:{main:"#8080FF"}}),Oe.palette.augmentColor({color:{main:"#8080FF"}}),Oe.palette.augmentColor({color:{main:"#80FF80"}}),Oe.palette.augmentColor({color:{main:"#FF8080"}})],bG=[null,Oe.palette.augmentColor({color:{main:"#8f8f8f"}}),Oe.palette.augmentColor({color:{main:"#adadad"}}),Oe.palette.augmentColor({color:{main:"#d8d8d8"}}),Oe.palette.augmentColor({color:{main:"#d8d8d8"}}),Oe.palette.augmentColor({color:{main:"#adadad"}}),Oe.palette.augmentColor({color:{main:"#8f8f8f"}})],IG="#e22",wG="#3e3",SG="#800080",BG="#808080",vG="#f00",TG="#00f",QG="#97b8c9",Pf={primary:hG,secondary:CG,tertiary:yG,quaternary:YQ,highlight:YQ,stopCodon:IG,startCodon:wG,insertion:SG,deletion:BG,softclip:TG,hardclip:vG,bases:xG,frames:bG,framesCDS:EG,skip:QG};uie={default:MG(),lightStock:_G(),lightMinimal:NG(),darkMinimal:DG(),darkStock:kG()}});var WQ=d(()=>{});var zQ=d(()=>{});var Gh=d(()=>{JQ();fh();WQ();zQ()});function So({value:e}){let{classes:t}=RG(),r=/^https?:\/\//.exec(`${e}`);return(0,Of.jsx)("div",{className:t.fieldValue,children:(0,KQ.isValidElement)(e)?e:r?(0,Of.jsx)(XQ.Link,{href:`${e}`,children:`${e}`}):(0,Of.jsx)(ho,{html:Ir(e)?JSON.stringify(e):String(e)})})}var Of,KQ,XQ,RG,Gf=d(()=>{Of=p(O(),1),KQ=p(k(),1),XQ=p(V(),1);Gh();Ao();$e();RG=X()(e=>({fieldValue:{wordBreak:"break-word",maxHeight:300,fontSize:12,padding:e.spacing(.5),overflow:"auto"}}))});function gn({description:e,name:t,width:r,prefix:n=[]}){let{classes:o}=LG(),i=[...n,t].join(".");return e?(0,Uf.jsx)(ZQ.Tooltip,{title:e,placement:"left",children:(0,Uf.jsx)("div",{className:Ou(o.fieldDescription,o.fieldName),children:i})}):(0,Uf.jsx)("div",{className:o.fieldName,style:{width:r},children:i})}var Uf,ZQ,LG,Fc=d(()=>{Uf=p(O(),1),ZQ=p(V(),1);$e();LG=X()(e=>({fieldDescription:{"&:hover":{background:e.palette.mode==="dark"?"#e65100":"yellow"}},fieldName:{wordBreak:"break-all",minWidth:90,borderBottom:"1px solid #0003",fontSize:12,background:e.palette.action.disabledBackground,marginRight:e.spacing(1),padding:e.spacing(.5)}}))});function Hh({name:e,value:t,description:r,formatter:n,prefix:o=[]}){let{classes:i}=FG(),[a,s]=(0,e2.useState)(!1),c=t.length>Uh,l=c&&!a?t.slice(0,Uh):t;return t.length===1?Ir(t[0])?(0,Pt.jsx)(hn,{formatter:n,attributes:t[0],prefix:[...o,e]}):(0,Pt.jsxs)("div",{className:i.field,children:[(0,Pt.jsx)(gn,{prefix:o,description:r,name:e}),(0,Pt.jsx)(So,{value:n?n(t[0],e):t[0]})]}):t.every(u=>Ir(u))?(0,Pt.jsx)(Pt.Fragment,{children:t.map((u,A)=>(0,Pt.jsx)(hn,{formatter:n,attributes:u,prefix:[...o,`${e}-${A}`]},`${JSON.stringify(u)}-${A}`))}):(0,Pt.jsxs)("div",{className:i.field,children:[(0,Pt.jsx)(gn,{prefix:o,description:r,name:e}),l.map((u,A)=>(0,Pt.jsx)("div",{className:i.fieldSubvalue,children:(0,Pt.jsx)(So,{value:n?n(u,e):u})},`${JSON.stringify(u)}-${A}`)),c?(0,Pt.jsx)("button",{type:"button",onClick:()=>{s(u=>!u)},children:a?"Show less":`Showing ${Uh} of ${t.length}. Show all...`}):null]})}var Pt,e2,Uh,FG,t2=d(()=>{Pt=p(O(),1),e2=p(k(),1);Hf();Gf();Fc();Ao();$e();Uh=100,FG=X()(e=>({field:{display:"flex",flexWrap:"wrap"},fieldSubvalue:{wordBreak:"break-word",maxHeight:300,padding:e.spacing(.5),border:`1px solid ${e.palette.action.selected}`,boxSizing:"border-box",overflow:"auto"}}))});var n2=z((Mie,r2)=>{r2.exports=JBrowseExports["@mui/x-data-grid"]});function Vh({children:e,style:t}){let{classes:r}=PG();return(0,o2.jsx)("div",{className:r.flexContainer,style:t,children:e})}var o2,PG,i2=d(()=>{o2=p(O(),1);$e();PG=X()({flexContainer:{display:"flex",flexDirection:"column"}})});function jh({value:e,prefix:t,name:r}){let{classes:n}=OG(),[o,i]=(0,a2.useState)(!1),a=Object.keys(e[0]).sort(),s=new Set(a),c=Object.entries(e).map(([A,m])=>{let{id:f,...g}=m;return{id:A,identifier:f,...g}});for(let A of e)for(let m of Object.keys(A))s.add(m);let l;s.has("id")?(s.delete("id"),l=["identifier",...s]):l=[...s];let u=l.map(A=>pv(c.map(m=>m[A])));return s.size<a.length+5?(0,Pr.jsxs)("div",{className:n.margin,children:[(0,Pr.jsx)(gn,{prefix:t,name:r}),(0,Pr.jsx)(es.FormControlLabel,{control:(0,Pr.jsx)(es.Checkbox,{checked:o,onChange:A=>{i(A.target.checked)}}),label:(0,Pr.jsx)(es.Typography,{variant:"body2",children:"Show options"})}),(0,Pr.jsx)(Vh,{children:(0,Pr.jsx)(s2.DataGrid,{disableRowSelectionOnClick:!0,rows:c,rowHeight:20,columnHeaderHeight:35,hideFooter:c.length<25,showToolbar:o,columns:l.map((A,m)=>({field:A,width:u[m],renderCell:({value:f})=>(0,Pr.jsx)("div",{className:n.cell,children:(0,Pr.jsx)(ho,{html:rh(f||"")})})}))})})]}):null}var Pr,a2,es,s2,OG,c2=d(()=>{Pr=p(O(),1),a2=p(k(),1),es=p(V(),1),s2=p(n2(),1);Fc();i2();Gh();Ao();$e();OG=X()(e=>({margin:{marginBottom:e.spacing(4)},cell:{whiteSpace:"nowrap",overflow:"hidden",textOverflow:"ellipsis"}}))});function Yh({name:e,value:t,description:r,prefix:n,width:o,formatter:i}){let{classes:a}=GG();return t!=null?(0,Pc.jsxs)("div",{className:a.field,children:[(0,Pc.jsx)(gn,{prefix:n,description:r,name:e,width:o}),(0,Pc.jsx)(So,{value:i?i(t,e):t})]}):null}var Pc,GG,l2=d(()=>{Pc=p(O(),1);Gf();Fc();$e();GG=X()({field:{display:"flex",flexWrap:"wrap"}})});function $h({value:e,prefix:t,name:r}){let{classes:n}=UG(),{uri:o,baseUri:i=""}=e,a;try{a=new URL(o,i).href}catch{a=o}return(0,Oc.jsxs)("div",{className:n.field,children:[(0,Oc.jsx)(gn,{prefix:t,name:r}),(0,Oc.jsx)(So,{value:a})]})}var Oc,UG,u2=d(()=>{Oc=p(O(),1);Gf();Fc();$e();UG=X()({field:{display:"flex",flexWrap:"wrap"}})});function f2(e,t){return e.map(r=>t.slice(r.start,r.end)).join("")}var A2=d(()=>{});function d2(e,t){return Math.ceil(nh(e.map(r=>eh([...t,r[0]].join("."),12))))+10}function m2(e,t={}){let r=t;for(let n of e)Ir(r)&&(r=r[n]);return typeof r=="string"?r:Ir(r)&&typeof r.Description=="string"?r.Description:void 0}var p2=d(()=>{Ao()});function hn(e){let{attributes:t,omit:r=[],omitSingleLevel:n=[],descriptions:o,formatter:i,hideUris:a,prefix:s=[]}=e,c=new Set([...r,...VG,...n]),{__jbrowsefmt:l,...u}=t,A=Object.entries({...u,...l}).filter(([f,g])=>g!=null&&!c.has(f)),m=d2(A,s);return(0,$n.jsx)($n.Fragment,{children:A.map(([f,g])=>{let y=m2([...s,f],o);if(Array.isArray(g))return g.length>1&&g.every(E=>Ir(E))?(0,$n.jsx)(jh,{name:f,prefix:s,value:g},f):(0,$n.jsx)(Hh,{name:f,value:g,formatter:i,description:y,prefix:s},f);if(Ir(g)){let{omitSingleLevel:E,...b}=e;return uf(g)?a?null:(0,$n.jsx)($h,{name:f,prefix:s,value:g},f):(0,$n.jsx)(hn,{...b,formatter:i,attributes:g,descriptions:o,prefix:[...s,f]},f)}else return(0,$n.jsx)(Yh,{name:f,formatter:i,value:g,description:y,prefix:s,width:Math.min(m,HG)},f)})})}var $n,HG,VG,Hf=d(()=>{$n=p(O(),1);t2();c2();l2();u2();p2();Ao();HG=170,VG=["__jbrowsefmt","length","position","subfeatures","uniqueId","exonFrames","parentId","thickStart","thickEnd","_lineHash"]});var g2,h2,C2=d(()=>{"use client";Xt();g2=p(O(),1),h2=(0,ve.createSvgIcon)((0,g2.jsx)("path",{d:"M16.59 8.59 12 13.17 7.41 8.59 6 10l6 6 6-6z"}),"ExpandMore")});function Ci({children:e,title:t,defaultExpanded:r=!0}){let{classes:n}=jG();return(0,hi.jsxs)(Bo.Accordion,{defaultExpanded:r,children:[(0,hi.jsx)(Bo.AccordionSummary,{expandIcon:(0,hi.jsx)(h2,{className:n.icon}),children:(0,hi.jsx)(Bo.Typography,{variant:"button",children:t})}),(0,hi.jsx)(Bo.AccordionDetails,{className:n.expansionPanelDetails,children:e})]})}var hi,Bo,jG,qh=d(()=>{hi=p(O(),1);C2();Bo=p(V(),1);$e();jG=X()(e=>({expansionPanelDetails:{display:"block",padding:e.spacing(1)},icon:{color:e.palette.tertiary.contrastText||"#fff"}}))});function yi({checked:e,label:t,disabled:r,onChange:n}){return Vf.default.createElement("div",null,Vf.default.createElement(jf.FormControlLabel,{control:Vf.default.createElement(jf.Checkbox,{disabled:r,checked:e,onChange:()=>{n()}}),label:t}))}var Vf,jf,Jh=d(()=>{Vf=p(k(),1),jf=p(V(),1)});function Gc({str:e}){let{classes:t}=YG(),[r,n]=(0,Or.useState)(!1),[o,i]=(0,Or.useState)(!1),[a,s]=(0,Or.useState)(!1),c=u=>u.replaceAll("-","").replaceAll(".",""),l=e.map(([u,A])=>[u,o?A:c(A)]).filter(([,u])=>a||!!u).map(([u,A])=>`>${u}
+${A}`).join(`
+`);return Or.default.createElement(Or.default.Fragment,null,Or.default.createElement(Yf.Button,{color:"primary",variant:"contained",onClick:()=>{Ac(l),n(!0),setTimeout(()=>{n(!1)},500)}},r?"Copied!":"Copy to clipboard"),Or.default.createElement(yi,{label:"Show gaps",checked:o,onChange:()=>{i(!o)}}),Or.default.createElement(yi,{label:"Show empty",checked:a,onChange:()=>{s(!a)}}),Or.default.createElement(Yf.TextField,{variant:"outlined",multiline:!0,className:t.dialogContent,minRows:5,maxRows:10,fullWidth:!0,value:l,slotProps:{input:{readOnly:!0,className:t.textAreaFont}}}))}var Or,Yf,YG,Wh=d(()=>{Or=p(k(),1);$e();Yf=p(V(),1);Jh();kp();YG=X()({textAreaFont:{fontFamily:"Courier New",wordWrap:"break-word"},dialogContent:{background:"lightgrey",margin:4,minWidth:"80em"}})});var b2={};bt(b2,{default:()=>qG});var ts,y2,x2,E2,$G,qG,I2=d(()=>{ts=p(k(),1);Hf();qh();y2=p(Ye(),1),x2=p(V(),1),E2=p($(),1);Wh();$G=(0,E2.observer)(function({model:e,onClose:t}){let{header:r}=e;return ts.default.createElement(y2.Dialog,{onClose:()=>{t()},open:!0,title:"Metadata",maxWidth:"xl"},ts.default.createElement(x2.DialogContent,null,ts.default.createElement(hn,{attributes:r}),ts.default.createElement(Ci,{title:"sequence"},ts.default.createElement(Gc,{str:e.rows}))))}),qG=$G});var S2={};bt(S2,{default:()=>w2});function w2({model:e,onClose:t}){let[r,n]=(0,Re.useState)(!0),[o,i]=(0,Re.useState)(!0),[a,s]=(0,Re.useState)("viewport"),[c,l]=(0,Re.useState)(),u=(0,Me.useTheme)(),{totalWidth:A,totalHeight:m,treeAreaWidth:f,turnedOnTracks:g,totalTrackAreaHeight:y}=e,E=g.length>0,b=A+f,x=m+(o?y:0),B=a==="entire"&&(b>1e4||x>1e4);return Re.default.createElement($f.Dialog,{onClose:()=>{t()},open:!0,title:"Export SVG"},Re.default.createElement(Me.DialogContent,null,c?Re.default.createElement($f.ErrorMessage,{error:c}):null,Re.default.createElement(Me.Typography,null,"Settings:"),Re.default.createElement(yi,{label:"Include minimap?",disabled:a==="entire",checked:r,onChange:()=>{n(!r)}}),E?Re.default.createElement(yi,{label:"Include tracks?",checked:o,onChange:()=>{i(!o)}}):null,Re.default.createElement("div",null,Re.default.createElement(Me.FormControl,null,Re.default.createElement(Me.FormLabel,null,"Export type"),Re.default.createElement(Me.RadioGroup,{value:a,onChange:I=>{let{value:w}=I.target;(w==="entire"||w==="viewport")&&s(w)}},Re.default.createElement(Me.FormControlLabel,{value:"entire",control:Re.default.createElement(Me.Radio,null),label:"Entire MSA"}),Re.default.createElement(Me.FormControlLabel,{value:"viewport",control:Re.default.createElement(Me.Radio,null),label:"Current viewport only"})))),B?Re.default.createElement(Me.Alert,{severity:"warning",style:{marginTop:8}},"The entire MSA is very large (",Math.round(b),"x",Math.round(x)," pixels). Export may be slow or fail."):null),Re.default.createElement(Me.DialogActions,null,Re.default.createElement(Me.Button,{variant:"contained",color:"primary",onClick:()=>{e.exportSVG({theme:u,includeMinimap:a==="entire"?!1:r,includeTracks:E&&o,exportType:a}).then(()=>{t()}).catch(I=>{console.error(I),l(I)})}},"Submit"),Re.default.createElement(Me.Button,{variant:"contained",color:"secondary",onClick:()=>{t()}},"Cancel")))}var Re,$f,Me,B2=d(()=>{Re=p(k(),1),$f=p(Ye(),1),Me=p(V(),1);Jh()});var rs,v2,JG,WG,zG,T2,Q2=d(()=>{rs=p(k(),1);Wa();kT();Ch();LT();PT();v2=p($(),1);NQ();JG=(0,rs.lazy)(()=>Promise.resolve().then(()=>(I2(),b2))),WG=(0,rs.lazy)(()=>Promise.resolve().then(()=>(B2(),S2))),zG=(0,v2.observer)(({model:e})=>rs.default.createElement(pn,{"data-testid":"file_menu",tooltip:"File",menuItems:[{label:"Return to import form",icon:Tf,onClick:()=>{e.reset()}},{label:"Metadata",icon:_T,onClick:()=>{e.queueDialog(t=>[JG,{model:e,onClose:t}])}},{label:"Domain settings",type:"subMenu",subMenu:DQ({model:e})},{label:"Export SVG",icon:FT,onClick:()=>{e.queueDialog(t=>[WG,{onClose:t,model:e}])}}],anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"}},rs.default.createElement(RT,null))),T2=zG});var qf,Jf,M2,KG,_2,k2=d(()=>{qf=p(k(),1),Jf=p(V(),1),M2=p($(),1),KG=(0,M2.observer)(function({model:t}){let{hideGaps:r,allowedGappyness:n}=t;return r?qf.default.createElement("div",{style:{display:"flex",alignItems:"center",gap:8}},qf.default.createElement(Jf.Typography,{style:{whiteSpace:"nowrap"}},"Hide columns w/ >",n,"% gaps"),qf.default.createElement(Jf.Slider,{style:{width:100},min:1,max:100,value:n,onChange:(o,i)=>{t.setAllowedGappyness(i)}})):null}),_2=KG});var Wf,D2,N2,XG,ZG,R2,L2=d(()=>{Wf=p(k(),1);$e();D2=p(V(),1),N2=p($(),1),XG=X()({container:{display:"flex",overflow:"hidden",margin:"auto",marginLeft:10},nameFirst:{overflow:"hidden",textOverflow:"ellipsis",whiteSpace:"nowrap",minWidth:0},nameRest:{whiteSpace:"nowrap",flexShrink:0}}),ZG=(0,N2.observer)(function({model:e}){let{mouseOverRowName:t,mouseCol:r}=e,{classes:n}=XG();if(!t||r===void 0)return null;let o=Math.floor(t.length/2),i=e.visibleColToSeqPosOneBased(t,r),a=e.visibleColToRowLetter(t,r);return Wf.default.createElement(D2.Typography,{component:"div",className:n.container,title:t},Wf.default.createElement("span",{className:n.nameFirst},t.slice(0,o)),Wf.default.createElement("span",{className:n.nameRest},t.slice(o),":",i," (",a,")"))}),R2=ZG});var Uc,F2,zf,P2,eU,tU,O2,G2=d(()=>{Uc=p(k(),1),F2=p(Ye(),1);$e();zf=p(V(),1),P2=p($(),1),eU=X()({margin:{margin:"auto",marginLeft:10}}),tU=(0,P2.observer)(({model:e})=>{let{status:t}=e,{classes:r}=eU();return t?Uc.default.createElement(zf.Typography,{className:r.margin},Uc.default.createElement(F2.LoadingEllipses,{message:t.msg,component:"span"})," ",t.url?Uc.default.createElement("a",{href:t.url,target:"_blank",rel:"noreferrer"},"(status)"):null," ",t.onCancel?Uc.default.createElement(zf.Button,{size:"small",onClick:()=>t.onCancel?.()},"Cancel"):null):null}),O2=tU});var U2,H2,V2=d(()=>{"use client";Ee();U2=p(O(),1),H2=Y((0,U2.jsx)("path",{d:"M3 17v2h6v-2zM3 5v2h10V5zm10 16v-2h8v-2h-8v-2h-2v6zM7 9v2H3v2h4v2h2V9zm14 4v-2H11v2zm-6-4h2V7h4V5h-4V3h-2z"}),"Tune")});function j2(e){let{drawMsaLetters:t,hideGaps:r,bgColor:n,showColumnStats:o}=e;return[{label:"Show column statistics on hover",type:"checkbox",checked:o,onClick:()=>{e.setShowColumnStats(!o)}},{label:"Draw letters",type:"checkbox",checked:t,onClick:()=>{e.setDrawMsaLetters(!t)}},{label:"Color letters instead of background of tiles",type:"checkbox",checked:!n,onClick:()=>{e.setBgColor(!n)}},{label:"Enable hiding gappy columns?",type:"checkbox",checked:r,onClick:()=>{e.setHideGaps(!r)}}]}function Y2(e){let{drawTree:t,showBranchLen:r,labelsAlignRight:n,drawNodeBubbles:o,drawLabels:i}=e;return[{label:"Show branch length",type:"checkbox",checked:r,onClick:()=>{e.setShowBranchLen(!r)}},{label:"Show tree",type:"checkbox",checked:t,onClick:()=>{e.setDrawTree(!t)}},{label:"Draw clickable bubbles on tree branches",type:"checkbox",checked:o,onClick:()=>{e.setDrawNodeBubbles(!o)}},{label:"Tree labels align right",type:"checkbox",checked:n,onClick:()=>{e.setLabelsAlignRight(!n)}},{label:"Draw labels",type:"checkbox",checked:i,onClick:()=>{e.setDrawLabels(!i)}}]}var zh=d(()=>{});var Kh,$2,rU,q2,J2=d(()=>{Kh=p(k(),1);Wa();V2();$2=p($(),1);zh();rU=(0,$2.observer)(function({model:e}){return Kh.default.createElement(pn,{"data-testid":"msa_settings_menu",tooltip:"Alignment settings",closeAfterItemClick:!1,anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"},menuItems:j2(e)},Kh.default.createElement(H2,null))}),q2=rU});var Xh,Kf,W2,nU,z2,K2=d(()=>{Xh=p(k(),1),Kf=p(V(),1),W2=p($(),1),nU=(0,W2.observer)(function({model:e}){let{currentAlignment:t,alignmentNames:r}=e,n=new Map;return r.length>0?Xh.default.createElement(Kf.TextField,{select:!0,variant:"outlined",value:t,size:"small",onChange:o=>{e.setCurrentAlignment(+o.target.value),e.setScrollX(0),e.setScrollY(0)}},r.map((o,i)=>{let a=n.get(o)??0;return n.set(o,a+1),Xh.default.createElement(Kf.MenuItem,{key:a===0?o:`${o}\0${a}`,value:i},o)})):null}),z2=nU});var X2,Z2,eM=d(()=>{"use client";Ee();X2=p(O(),1),Z2=Y((0,X2.jsx)("path",{d:"M22 11V3h-7v3H9V3H2v8h7V8h2v10h4v3h7v-8h-7v3h-2V8h2v3z"}),"AccountTree")});var Zh,tM,oU,rM,nM=d(()=>{Zh=p(k(),1);Wa();eM();tM=p($(),1);zh();oU=(0,tM.observer)(function({model:e}){let{rows:t}=e;return Zh.default.createElement(pn,{"data-testid":"tree_settings_menu",tooltip:"Tree settings",closeAfterItemClick:!1,anchorOrigin:{vertical:"bottom",horizontal:"left"},transformOrigin:{vertical:"top",horizontal:"left"},menuItems:[...Y2(e),...t.length>=2?[{label:"Advanced",type:"subMenu",subMenu:[{label:"Calculate neighbor joining tree (BLOSUM62)",onClick:()=>{try{e.calculateNeighborJoiningTreeFromMSA()}catch(r){console.error("Failed to calculate NJ tree:",r),e.setError(r)}}}]}]:[]]},Zh.default.createElement(Z2,null))}),rM=oU});var oM,iM,aM=d(()=>{"use client";Ee();oM=p(O(),1),iM=Y((0,oM.jsx)("path",{d:"M13 1.07V9h7c0-4.08-3.05-7.44-7-7.93M4 15c0 4.42 3.58 8 8 8s8-3.58 8-8v-4H4zm7-13.93C7.05 1.56 4 4.92 4 9h7z"}),"Mouse")});var e0,sM,cM=d(()=>{"use client";Ee();e0=p(O(),1),sM=Y([(0,e0.jsx)("path",{d:"M15.5 14h-.79l-.28-.27C15.41 12.59 16 11.11 16 9.5 16 5.91 13.09 3 9.5 3S3 5.91 3 9.5 5.91 16 9.5 16c1.61 0 3.09-.59 4.23-1.57l.27.28v.79l5 4.99L20.49 19zm-6 0C7.01 14 5 11.99 5 9.5S7.01 5 9.5 5 14 7.01 14 9.5 11.99 14 9.5 14"},"0"),(0,e0.jsx)("path",{d:"M12 10h-2v2H9v-2H7V9h2V7h1v2h2z"},"1")],"ZoomIn")});var lM,uM,fM=d(()=>{"use client";Ee();lM=p(O(),1),uM=Y((0,lM.jsx)("path",{d:"M15.5 14h-.79l-.28-.27C15.41 12.59 16 11.11 16 9.5 16 5.91 13.09 3 9.5 3S3 5.91 3 9.5 5.91 16 9.5 16c1.61 0 3.09-.59 4.23-1.57l.27.28v.79l5 4.99L20.49 19zm-6 0C7.01 14 5 11.99 5 9.5S7.01 5 9.5 5 14 7.01 14 9.5 11.99 14 9.5 14M7 9h5v1H7z"}),"ZoomOut")});var Gr,vo,AM,iU,dM,mM=d(()=>{Gr=p(k(),1);aM();cM();fM();vo=p(V(),1),AM=p($(),1),iU=(0,AM.observer)(function({model:t}){return Gr.default.createElement(Gr.default.Fragment,null,Gr.default.createElement(vo.Tooltip,{title:"Zoom in"},Gr.default.createElement(vo.IconButton,{"aria-label":"Zoom in",onClick:()=>{t.zoomIn()}},Gr.default.createElement(sM,null))),Gr.default.createElement(vo.Tooltip,{title:"Zoom out"},Gr.default.createElement(vo.IconButton,{"aria-label":"Zoom out",onClick:()=>{t.zoomOut()}},Gr.default.createElement(uM,null))),Gr.default.createElement(vo.ToggleButton,{value:"scrollZoom",selected:t.scrollZoom,"aria-label":"Toggle scroll-to-zoom",title:"Toggle scroll-to-zoom (zoom on plain mouse wheel; ctrl+wheel always zooms)",size:"small",sx:{border:"none"},onChange:()=>{t.setScrollZoom(!t.scrollZoom)}},Gr.default.createElement(iM,null)))}),dM=iU});var pM,gM,hM=d(()=>{"use client";Ee();pM=p(O(),1),gM=Y((0,pM.jsx)("path",{d:"M12 8c1.1 0 2-.9 2-2s-.9-2-2-2-2 .9-2 2 .9 2 2 2m0 2c-1.1 0-2 .9-2 2s.9 2 2 2 2-.9 2-2-.9-2-2-2m0 6c-1.1 0-2 .9-2 2s.9 2 2 2 2-.9 2-2-.9-2-2-2"}),"MoreVert")});var CM,yM,xM=d(()=>{"use client";Ee();CM=p(O(),1),yM=Y((0,CM.jsx)("path",{d:"M12 5V2L8 6l4 4V7c3.31 0 6 2.69 6 6 0 2.97-2.17 5.43-5 5.91v2.02c3.95-.49 7-3.85 7-7.93 0-4.42-3.58-8-8-8m-6 8c0-1.65.67-3.15 1.76-4.24L6.34 7.34C4.9 8.79 4 10.79 4 13c0 4.08 3.05 7.44 7 7.93v-2.02c-2.83-.48-5-2.94-5-5.91"}),"RestartAlt")});var t0,EM,aU,bM,IM=d(()=>{t0=p(k(),1);Wa();hM();xM();EM=p($(),1),aU=(0,EM.observer)(function({model:e}){return t0.default.createElement(pn,{tooltip:"Fit / zoom options",menuItems:[{label:"Fit both vertically/horizontally",onClick:()=>{e.fit()}},{label:"Fit vertically",onClick:()=>{e.fitVertically()}},{label:"Fit horizontally",onClick:()=>{e.fitHorizontally()}},{label:"Reset zoom to default",icon:yM,onClick:()=>{e.resetZoom()}}]},t0.default.createElement(gM,null))}),bM=aU});var wM,SM=d(()=>{wM="5.6.3"});var TM={};bt(TM,{default:()=>vM});function vM({onClose:e}){return nt.default.createElement(BM.Dialog,{open:!0,title:"About",onClose:()=>{e()}},nt.default.createElement(Ot.DialogContent,null,nt.default.createElement(Ot.Typography,null,"MSAView ",wM," (",nt.default.createElement(Ot.Link,{href:"https://github.com/gmod/react-msaview"},"Github"),")"),nt.default.createElement("ul",null,nt.default.createElement("li",null,nt.default.createElement(Ot.Typography,null,"We use some color schemes from the"," ",nt.default.createElement(Ot.Link,{href:"https://github.com/biotite-dev/biotite"},"biotite")," ","project, and their license is reproduced"," ",nt.default.createElement(Ot.Link,{href:"https://github.com/biotite-dev/biotite/blob/master/LICENSE.rst"},"here"))),nt.default.createElement("li",null,nt.default.createElement(Ot.Typography,null,"See this page for some information on jalview colorings"," ",nt.default.createElement(Ot.Link,{href:"https://www.jalview.org/help/html/colourSchemes/"},"here"))),nt.default.createElement("li",null,nt.default.createElement(Ot.Typography,null,"See this page for some info on the clustal, cinema, maeditor, and lesk color schemes"," ",nt.default.createElement(Ot.Link,{href:"http://www.bioinformatics.nl/~berndb/aacolour.html"},"here"))),nt.default.createElement("li",null,nt.default.createElement(Ot.Typography,null,"See this paper about the flower color scheme"," ",nt.default.createElement(Ot.Link,{href:"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7245768/"},"here"))))))}var nt,BM,Ot,QM=d(()=>{nt=p(k(),1),BM=p(Ye(),1),Ot=p(V(),1);SM()});function lU(){return Ue.default.createElement("div",{style:{flex:1}})}var Ue,Xf,MM,sU,cU,_M,kM=d(()=>{Ue=p(k(),1);bw();Sw();Xf=p(V(),1),MM=p($(),1);QT();Q2();k2();L2();G2();J2();K2();nM();mM();IM();sU=(0,Ue.lazy)(()=>Promise.resolve().then(()=>(QM(),TM))),cU=(0,MM.observer)(function({model:e}){let[t,{height:r}]=Np();return(0,Ue.useEffect)(()=>{e.setHeaderHeight(r??0)},[e,r]),Ue.default.createElement("div",{ref:t,style:{display:"flex"}},Ue.default.createElement(T2,{model:e}),Ue.default.createElement(TT,{model:e}),Ue.default.createElement(rM,{model:e}),Ue.default.createElement(q2,{model:e}),Ue.default.createElement(dM,{model:e}),Ue.default.createElement(bM,{model:e}),Ue.default.createElement(_2,{model:e}),Ue.default.createElement("div",{style:{paddingLeft:20,margin:"auto"}},Ue.default.createElement(z2,{model:e})),Ue.default.createElement(R2,{model:e}),Ue.default.createElement(lU,null),Ue.default.createElement(O2,{model:e}),Ue.default.createElement(Xf.Tooltip,{title:"About"},Ue.default.createElement(Xf.IconButton,{"aria-label":"About",onClick:()=>{e.queueDialog(n=>[sU,{onClose:n}])}},Ue.default.createElement(ww,null))))});_M=cU});var Cn,DM,uU,NM,RM=d(()=>{Cn=p(k(),1),DM=p($(),1);Km();Fu();uU=(0,DM.observer)(function({model:e}){let[t,r]=(0,Cn.useState)(!1),{minimapHeight:n}=e,{unit:o,s:i,w:a,polygonHeight:s,polygonPoints:c}=Eu(e),l="rgba(66, 119, 127, 0.3)",{startDrag:u}=co("x",(0,Cn.useCallback)((A,m)=>{e.setScrollX(m-A/o)},[e,o]));return Cn.default.createElement("div",{style:{position:"relative",height:n,width:"100%"}},Cn.default.createElement("div",{style:{height:12,boxSizing:"border-box",border:"1px solid #555"}}),Cn.default.createElement("div",{style:{position:"absolute",top:0,left:Math.max(0,i),background:t?"rgba(66,119,127,0.6)":l,cursor:"pointer",height:12,width:a,zIndex:100},onMouseOver:()=>{r(!0)},onMouseOut:()=>{r(!1)},onMouseDown:A=>{u(A,e.scrollX)}}),Cn.default.createElement("svg",{height:s,style:{width:"100%"}},Cn.default.createElement("polygon",{fill:l,points:c})))}),NM=uU});var LM,FM,PM=d(()=>{"use client";Ee();LM=p(O(),1),FM=Y((0,LM.jsx)("path",{d:"m12 8-6 6 1.41 1.41L12 10.83l4.59 4.58L18 14z"}),"ExpandLess")});var OM,Zf,r0=d(()=>{"use client";Ee();OM=p(O(),1),Zf=Y((0,OM.jsx)("path",{d:"M16.59 8.59 12 13.17 7.41 8.59 6 10l6 6 6-6z"}),"ExpandMore")});var Ur,ns,GM,fU,UM,HM=d(()=>{Ur=p(k(),1);PM();r0();ns=p(V(),1),GM=p($(),1),fU=(0,GM.observer)(function({model:e}){let[t,r]=(0,Ur.useState)(!0),{actuallyShowDomains:n,visibleDomainTypes:o,fillPalette:i}=e,a=t?FM:Zf;return n&&o.length>0?Ur.default.createElement(ns.Paper,{elevation:3,style:{position:"absolute",top:4,right:4,zIndex:100,maxWidth:260,maxHeight:"60%",display:"flex",flexDirection:"column",opacity:.95}},Ur.default.createElement("div",{style:{display:"flex",alignItems:"center",justifyContent:"flex-end",padding:"2px 4px 2px 8px"}},Ur.default.createElement(ns.IconButton,{size:"small",onClick:()=>{r(!t)}},Ur.default.createElement(a,{fontSize:"small"}))),t?Ur.default.createElement("div",{style:{overflow:"auto",padding:"0 8px 6px"}},o.map(({accession:s,name:c})=>Ur.default.createElement("div",{key:s,style:{display:"flex",alignItems:"center",gap:6},title:s},Ur.default.createElement("div",{style:{width:12,height:12,flexShrink:0,background:i[s]}}),Ur.default.createElement(ns.Typography,{variant:"caption",noWrap:!0},c)))):null):null}),UM=fU});function n0(){return eA.default.createElement("div",{style:{position:"absolute",left:"50%",top:"50%"}},eA.default.createElement(tA.CircularProgress,null),eA.default.createElement(tA.Typography,null,"Loading..."))}var eA,tA,VM=d(()=>{eA=p(k(),1),tA=p(V(),1)});var ar,jM,o0,AU,YM,$M=d(()=>{ar=p(k(),1),jM=p($(),1),o0=e=>`${Math.round(e*100)}%`,AU=(0,jM.observer)(function({model:e}){let t=e.mouseOverColumnStats;if(!t)return null;let{col:r,total:n,conservation:o,propertyConservation:i,consensusLetter:a,consensusFraction:s,gapFraction:c,distribution:l}=t,u=l.slice(0,6);return ar.default.createElement("div",null,ar.default.createElement("b",null,"Column ",r+1)," (",n," seqs)",ar.default.createElement("br",null),"Consensus: ",a||"-"," (",o0(s),")",ar.default.createElement("br",null),"Conservation: ",o.toFixed(2),i===void 0?null:ar.default.createElement(ar.default.Fragment,null,ar.default.createElement("br",null),"Property conservation: ",i.toFixed(2)),ar.default.createElement("br",null),"Gaps: ",o0(c),u.length>0?ar.default.createElement(ar.default.Fragment,null,ar.default.createElement("br",null),u.map(([A,m])=>ar.default.createElement("span",{key:A,style:{marginRight:8}},A," ",o0(m/n)))):null)}),YM=AU});function dU({event:e,el:t,offsetX:r,offsetY:n,colWidth:o,rowHeight:i}){let{left:a,top:s}=t.getBoundingClientRect();return{col:Math.floor((e.clientX-a+r)/o),row:Math.floor((e.clientY-s+n)/i)}}function JM({model:e,offsetX:t,offsetY:r}){let[n,o]=(0,qM.useState)();function i(l,u){let{colWidth:A,rowHeight:m}=e;return dU({event:l,el:u,offsetX:t,offsetY:r,colWidth:A,rowHeight:m})}function a(l,u){let{col:A,row:m}=i(l,u),f=A>=0&&A<e.numColumns&&m>=0&&m<e.numRows;e.setMousePos(f?A:void 0,f?m:void 0);let g=!!e.hoveredInsertion||e.mouseOverDomains.length>0||e.showColumnStats&&!!e.mouseOverColumnStats;o(g?{x:l.clientX,y:l.clientY}:void 0)}function s(l,u){let{col:A,row:m}=i(l,u),{mouseClickCol:f,mouseClickRow:g}=e,y=A===f&&m===g;e.setMouseClickPos(y?void 0:A,y?void 0:m)}function c(){e.setMousePos(),o(void 0)}return{tooltipPoint:n,onMouseMove:a,onClick:s,onMouseLeave:c}}var qM,WM=d(()=>{qM=p(k(),1)});function wr(e,t){let r=(0,rA.useRef)(null);return(0,rA.useEffect)(()=>{let n=r.current?.getContext("2d");return n?(0,zM.autorun)(()=>{e(n)}):void 0},t),r}var rA,zM,xi=d(()=>{rA=p(k(),1),zM=p(Ca(),1)});function nA(e){let t=(0,XM.useTheme)(),r=(0,KM.useMemo)(()=>nc(e,t),[e,t]);return{theme:t,contrastScheme:r}}var KM,XM,i0=d(()=>{KM=p(k(),1),XM=p(V(),1);so()});var Gt,ZM,e_,mU,t_,r_=d(()=>{Gt=p(k(),1),ZM=p(Ye(),1),e_=p($(),1);$M();ep();Ap();WM();xi();i0();mU=(0,e_.observer)(function({model:e,offsetX:t,offsetY:r}){let{scrollY:n,scrollX:o,colorScheme:i,blockSize:a,highResScaleFactor:s}=e,{theme:c,contrastScheme:l}=nA(i),{tooltipPoint:u,onMouseMove:A,onClick:m,onMouseLeave:f}=JM({model:e,offsetX:t,offsetY:r}),g=wr(x=>{let{blockSize:B,highResScaleFactor:I,actuallyShowDomains:w}=e;x.resetTransform(),x.clearRect(0,0,B*I,B*I),w&&Bu({ctx:x,offsetX:t,offsetY:r,model:e}),_u({ctx:x,theme:c,offsetX:t,offsetY:r,contrastScheme:l,model:e})},[e,t,r,c,l]),{hoveredInsertion:y,mouseOverDomains:E,showColumnStats:b}=e;return Gt.default.createElement(Gt.default.Fragment,null,Gt.default.createElement("canvas",{ref:g,onMouseMove:x=>{g.current&&A(x,g.current)},onClick:x=>{g.current&&m(x,g.current)},onMouseLeave:()=>{f()},width:a*s,height:a*s,style:{position:"absolute",top:n+r,left:o+t,width:a,height:a}}),u?Gt.default.createElement(ZM.BaseTooltip,{clientPoint:{x:u.x,y:u.y+15}},y?Gt.default.createElement(Gt.default.Fragment,null,"Insertion (",y.letters.length,e.sequenceType==="amino"?"aa":"bp","):"," ",y.letters.length>20?`${y.letters.slice(0,20)}...`:y.letters):Gt.default.createElement(Gt.default.Fragment,null,E.map(x=>Gt.default.createElement("div",{key:`${x.accession}-${x.start}-${x.end}`},Gt.default.createElement("b",null,x.name)," (",x.accession,") ",x.start,"-",x.end,x.description?Gt.default.createElement(Gt.default.Fragment,null,Gt.default.createElement("br",null),x.description):null)),b?Gt.default.createElement(YM,{model:e}):null)):null)}),t_=mU});var yn,n_,pU,o_,i_=d(()=>{yn=p(k(),1),n_=p($(),1);VM();r_();Gu();pU=(0,n_.observer)(function({model:e}){let{MSA:t,verticalScrollbarWidth:r,msaFilehandle:n,height:o,msaAreaWidth:i,blocks2d:a,scrollZoom:s}=e,c=(0,yn.useRef)(null),l=(0,yn.useCallback)(g=>{e.doScrollX(g)},[e]),u=(0,yn.useCallback)(g=>{e.doScrollY(g)},[e]),A=(0,yn.useCallback)((g,y,E)=>{e.zoomToPos(g,y,E)},[e]),{onMouseDown:m,onMouseUp:f}=Ba({ref:c,onScrollX:l,onScrollY:u,onZoom:A,scrollZoom:s});return yn.default.createElement("div",{ref:c,onMouseDown:m,onMouseUp:f,onMouseLeave:g=>{g.preventDefault()},style:{position:"relative",height:o,width:i-r,overflow:"hidden"}},!t&&!n?null:t?a.map(([g,y])=>yn.default.createElement(t_,{key:`${g}_${y}`,model:e,offsetX:g,offsetY:y})):yn.default.createElement(n0,null))}),o_=pU});var oA,a_,s_,a0=d(()=>{oA="rgba(0,128,255,0.3)",a_="rgba(255,165,0,0.2)",s_="rgba(255,165,0,0.15)"});function u_({ctx:e,model:t}){let{mouseCol:r,colWidth:n,msaAreaWidth:o,verticalScrollbarWidth:i,height:a,rowHeight:s,scrollX:c,scrollY:l,mouseRow:u,mouseClickRow:A,mouseClickCol:m,highResScaleFactor:f,referenceRowIndex:g,hoveredRowIndices:y,highlightedColumnRuns:E}=t,b=o-i;if(e.resetTransform(),e.clearRect(0,0,b*f,a*f),e.scale(f,f),g!==void 0&&(e.fillStyle=oA,e.fillRect(0,g*s+l,b,s)),y.length>0){e.fillStyle=s_;for(let x of y)e.fillRect(0,x*s+l,b,s)}if(E.length>0){e.lineWidth=2;for(let{start:x,end:B}of E){let I=x*n+c,w=(B-x+1)*n;e.fillStyle=gU,e.fillRect(I,0,w,a),e.strokeStyle=hU,e.strokeRect(I,0,w,a)}}r!==void 0&&(e.fillStyle=c_,e.fillRect(r*n+c,0,n,a)),u!==void 0&&(e.fillStyle=c_,e.fillRect(0,u*s+l,b,s)),m!==void 0&&(e.fillStyle=l_,e.fillRect(m*n+c,0,n,a)),A!==void 0&&(e.fillStyle=l_,e.fillRect(0,A*s+l,b,s))}var c_,l_,gU,hU,f_=d(()=>{a0();c_="rgba(0,0,0,0.15)",l_="rgba(128,128,0,0.2)",gU="rgba(255,140,0,0.28)",hU="rgba(210,90,0,0.95)"});var A_,d_,m_,CU,p_,g_=d(()=>{A_=p(k(),1),d_=p(Vt(),1),m_=p($(),1);f_();xi();CU=(0,m_.observer)(function({model:e}){let{height:t,msaAreaWidth:r,verticalScrollbarWidth:n,highResScaleFactor:o}=e,i=r-n,a=wr(s=>{(0,d_.isAlive)(e)&&u_({ctx:s,model:e})},[e]);return A_.default.createElement("canvas",{ref:a,id:"mouseover",width:i*o,height:t*o,style:{position:"absolute",top:0,left:0,width:i,height:t,zIndex:1e3,pointerEvents:"none"}})}),p_=CU});var Hc,h_,yU,C_,y_=d(()=>{Hc=p(k(),1),h_=p($(),1);HM();i_();g_();yU=(0,h_.observer)(function({model:e}){return Hc.default.createElement("div",{style:{position:"relative"}},Hc.default.createElement(o_,{model:e}),Hc.default.createElement(p_,{model:e}),Hc.default.createElement(UM,{model:e}))}),C_=yU});var Vc,os,x_,xU,E_,b_=d(()=>{Vc=p(k(),1),os=p(V(),1),x_=p($(),1),xU=(0,x_.observer)(function({node:e,model:t,onClose:r}){return Vc.default.createElement(os.Menu,{anchorReference:"anchorPosition",anchorPosition:{left:e.x,top:e.y},transitionDuration:0,keepMounted:!0,open:!!e,onClose:r},Vc.default.createElement(os.MenuItem,{dense:!0,disabled:!0},e.name),Vc.default.createElement(os.MenuItem,{dense:!0,onClick:()=>{t.toggleCollapsed(e.id),r()}},t.collapsed.includes(e.id)?"Expand this node":"Collapse this node"),Vc.default.createElement(os.MenuItem,{dense:!0,onClick:()=>{t.showOnly===e.id?t.setShowOnly(void 0):t.setShowOnly(e.id),r()}},t.showOnly===e.id?"Disable show only this node":"Show only this node"))}),E_=xU});var B_={};bt(B_,{default:()=>bU});var xn,I_,w_,S_,EU,bU,v_=d(()=>{xn=p(k(),1);Hf();qh();I_=p(Ye(),1),w_=p(V(),1),S_=p($(),1);Wh();EU=(0,S_.observer)(function({info:e,model:t,nodeName:r,onClose:n}){let{treeMetadata:o,rows:i}=t,a=o[r],s=i.find(c=>c[0]===r);return xn.default.createElement(I_.Dialog,{onClose:()=>{n()},open:!0,title:"Tree node info",maxWidth:"xl"},xn.default.createElement(w_.DialogContent,null,xn.default.createElement(Ci,{title:"Attributes"},xn.default.createElement(hn,{attributes:{nodeName:r,...e}})),xn.default.createElement(Ci,{title:"Sequence"},s?xn.default.createElement(Gc,{str:[s]}):xn.default.createElement("div",null,"Sequence not found")),a?xn.default.createElement(Ci,{title:"Extra metadata"},xn.default.createElement(hn,{attributes:a})):null))}),bU=EU});var qn,To,T_,IU,wU,Q_,M_=d(()=>{qn=p(k(),1),To=p(V(),1),T_=p($(),1),IU=(0,qn.lazy)(()=>Promise.resolve().then(()=>(v_(),B_))),wU=(0,T_.observer)(function({node:e,onClose:t,model:r}){let{collapsed:n}=r,{name:o,id:i}=e,a=n.includes(i);return qn.default.createElement(To.Menu,{anchorReference:"anchorPosition",anchorPosition:{top:e.y,left:e.x},transitionDuration:0,keepMounted:!0,open:!!e,onClose:t},qn.default.createElement(To.MenuItem,{dense:!0,disabled:!0},o),qn.default.createElement(To.MenuItem,{dense:!0,onClick:()=>{r.queueDialog(s=>[IU,{info:r.getRowData(o),model:r,nodeName:o,onClose:s}]),t()}},"More info..."),qn.default.createElement(To.MenuItem,{dense:!0,onClick:()=>{r.toggleCollapsed(i),t()}},a?"Expand subtree":"Collapse subtree"),qn.default.createElement(To.MenuItem,{dense:!0,onClick:()=>{r.drawRelativeTo(e.name),t()}},"Indicate differences from this row"),r.relativeTo?qn.default.createElement(To.MenuItem,{dense:!0,onClick:()=>{r.drawRelativeTo(void 0),t()}},"Clear reference row"):null)}),Q_=wU});var jc,__=d(()=>{jc=class{constructor(t=1/0,r=Float64Array,n=Uint32Array){let o=t!==1/0;this.ids=o?new n(t):[],this.values=o?new r(t):[],this.capacity=t,this.length=0}clear(){this.length=0}push(t,r){if(this.length===this.capacity)throw new RangeError("Queue is at capacity.");let n=this.length++;for(;n>0;){let o=n-1>>1,i=this.values[o];if(r>=i)break;this.ids[n]=this.ids[o],this.values[n]=i,n=o}this.ids[n]=t,this.values[n]=r}pop(){if(this.length===0)return;let t=this.ids,r=this.values,n=t[0],o=--this.length;if(o>0){let i=t[o],a=r[o],s=0,c=o>>1;for(;s<c;){let l=(s<<1)+1,u=l+1,A=l+(+(u<o)&+(r[u]<r[l]));if(r[A]>=a)break;t[s]=t[A],r[s]=r[A],s=A}t[s]=i,r[s]=a}return n}peek(){return this.length>0?this.ids[0]:void 0}peekValue(){return this.length>0?this.values[0]:void 0}shrink(){Array.isArray(this.ids)&&(this.ids.length=this.length),Array.isArray(this.values)&&(this.values.length=this.length)}}});function SU(e,t){let r=0,n=t.length-1;for(;r<n;){let o=r+n>>1;t[o]>e?n=o:r=o+1}return t[r]}function BU(e,t,r,n,o,i){let a=[n,o];for(;a.length;){let s=a.pop()||0,c=a.pop()||0;if(s-c<=i&&Math.floor(c/i)>=Math.floor(s/i))continue;let l=e[c],u=e[c+s>>1],A=e[s],m=l>u!=l>A?l:u<l!=u<A?u:A,f=c-1,g=s+1;for(;;){do f++;while(e[f]<m);do g--;while(e[g]>m);if(f>=g)break;vU(e,t,r,f,g)}a.push(c,g,g+1,s)}}function vU(e,t,r,n,o){let i=e[n];e[n]=e[o],e[o]=i;let a=4*n,s=4*o,c=t[a],l=t[a+1],u=t[a+2],A=t[a+3];t[a]=t[s],t[a+1]=t[s+1],t[a+2]=t[s+2],t[a+3]=t[s+3],t[s]=c,t[s+1]=l,t[s+2]=u,t[s+3]=A;let m=r[n];r[n]=r[o],r[o]=m}function TU(e,t){let r=e^t,n=65535^r,o=65535^(e|t),i=e&(t^65535),a=r|n>>1,s=r>>1^r,c=o^(o>>1^n&i>>1),l=i^(r&o>>1^i>>1);return r=a&a>>2^s&s>>2,n=a&s>>2^s&(a^s)>>2,o=c^(a&c>>2^s&l>>2),i=l^(s&c>>2^(a^s)&l>>2),a=r&r>>4^n&n>>4,s=r&n>>4^n&(r^n)>>4,c=o^(r&o>>4^n&i>>4),l=i^(n&o>>4^(r^n)&i>>4),o=c^(a&c>>8^s&l>>8),i=l^(s&c>>8^(a^s)&l>>8),o^=o>>1,i^=i>>1,r=e^t,n=i|65535^(r|o),r=(r|r<<8)&16711935,r=(r|r<<4)&252645135,r=(r|r<<2)&858993459,r=(r|r<<1)&1431655765,n=(n|n<<8)&16711935,n=(n|n<<4)&252645135,n=(n|n<<2)&858993459,n=(n|n<<1)&1431655765,((n<<1|r)>>>0)-2147483648}var k_,s0,Yc,D_=d(()=>{__();k_=[Int8Array,Uint8Array,Uint8ClampedArray,Int16Array,Uint16Array,Int32Array,Uint32Array,Float32Array,Float64Array],s0=3,Yc=class e{static from(t,r=0){if(r%8!==0)throw new Error("byteOffset must be 8-byte aligned.");if(!t||t.byteLength===void 0||"buffer"in t)throw new Error("Data must be an instance of ArrayBuffer or SharedArrayBuffer.");let[n,o]=new Uint8Array(t,r+0,2);if(n!==251)throw new Error("Data does not appear to be in a Flatbush format.");let i=o>>4;if(i!==s0)throw new Error(`Got v${i} data when expected v${s0}.`);let a=k_[o&15];if(!a)throw new Error("Unrecognized array type.");let[s]=new Uint16Array(t,r+2,1),[c]=new Uint32Array(t,r+4,1);return new e(c,s,a,void 0,t,r)}constructor(t,r=16,n=Float64Array,o=ArrayBuffer,i,a=0){if(t===void 0)throw new Error("Missing required argument: numItems.");if(isNaN(t)||t<=0)throw new Error(`Unexpected numItems value: ${t}.`);this.numItems=+t,this.nodeSize=Math.min(Math.max(+r,2),65535),this.byteOffset=a;let s=t,c=s;this._levelBounds=[s*4];do s=Math.ceil(s/this.nodeSize),c+=s,this._levelBounds.push(c*4);while(s!==1);this.ArrayType=n,this.IndexArrayType=c<16384?Uint16Array:Uint32Array;let l=k_.indexOf(n),u=c*4*n.BYTES_PER_ELEMENT;if(l<0)throw new Error(`Unexpected typed array class: ${n}.`);let A=n,m=this.IndexArrayType;if(i)this.data=i,this._boxes=new A(i,a+8,c*4),this._indices=new m(i,a+8+u,c),this._pos=c*4,this.minX=this._boxes[this._pos-4],this.minY=this._boxes[this._pos-3],this.maxX=this._boxes[this._pos-2],this.maxY=this._boxes[this._pos-1];else{let f=this.data=new o(8+u+c*this.IndexArrayType.BYTES_PER_ELEMENT);this._boxes=new A(f,8,c*4),this._indices=new m(f,8+u,c),this._pos=0,this.minX=1/0,this.minY=1/0,this.maxX=-1/0,this.maxY=-1/0,new Uint8Array(f,0,2).set([251,(s0<<4)+l]),new Uint16Array(f,2,1)[0]=r,new Uint32Array(f,4,1)[0]=t}this._queue=new jc}add(t,r,n=t,o=r){let i=this._pos,a=i>>2,s=this._boxes;return this._indices[a]=a,s[i]=t,s[i+1]=r,s[i+2]=n,s[i+3]=o,this._pos=i+4,t<this.minX&&(this.minX=t),r<this.minY&&(this.minY=r),n>this.maxX&&(this.maxX=n),o>this.maxY&&(this.maxY=o),a}finish(){if(this._pos>>2!==this.numItems)throw new Error(`Added ${this._pos>>2} items when expected ${this.numItems}.`);let t=this._boxes;if(this.numItems<=this.nodeSize){t[this._pos++]=this.minX,t[this._pos++]=this.minY,t[this._pos++]=this.maxX,t[this._pos++]=this.maxY;return}let{numItems:r,minX:n,minY:o,nodeSize:i,_indices:a,_levelBounds:s}=this,c=this.maxX-n||1,l=this.maxY-o||1,u=new Int32Array(r),A=65535,m=A/c,f=A/l;for(let y=0,E=0;y<r;y++){let b=t[E++],x=t[E++],B=t[E++],I=t[E++],w=m*((b+B)/2-n)|0,S=f*((x+I)/2-o)|0;u[y]=TU(w,S)}BU(u,t,a,0,r-1,i);let g=r*4;for(let y=0,E=0;y<s.length-1;y++){let b=s[y];for(;E<b;){let x=E,B=t[E++],I=t[E++],w=t[E++],S=t[E++];for(let v=1;v<i&&E<b;v++)B=Math.min(B,t[E++]),I=Math.min(I,t[E++]),w=Math.max(w,t[E++]),S=Math.max(S,t[E++]);a[g>>2]=x,t[g++]=B,t[g++]=I,t[g++]=w,t[g++]=S}}this._pos=g}search(t,r,n,o,i){if(this._pos!==this._boxes.length)throw new Error("Data not yet indexed - call index.finish().");let{_boxes:a,_levelBounds:s,_indices:c,nodeSize:l}=this,u=this.numItems*4,A=a.length-4,m=s.length-1,f=[],g=[],y=!1;for(;A!==void 0;){let E=Math.min(A+l*4,s[m]),b=A>=u;if(y)this._collectContained(A,E,m,u,g,i);else for(let x=A;x<E;x+=4){let B=a[x];if(n<B)continue;let I=a[x+1];if(o<I)continue;let w=a[x+2];if(t>w)continue;let S=a[x+3];if(r>S)continue;let v=c[x>>2]|0;if(b){let D=+(t<=B&&r<=I&&n>=w&&o>=S);f.push(v|D,m-1)}else(i===void 0||i(v,B,I,w,S))&&g.push(v)}m=f.pop(),A=f.pop(),A!==void 0&&(y=(A&1)===1,A&=-2)}return g}_collectContained(t,r,n,o,i,a){let s=this._boxes,c=this._indices,l=t;for(let A=n;A>0;A--)l=c[l>>2];let u=Math.min(l+(r-t)*this.nodeSize**n,o);if(a===void 0)for(;l<u;l+=4)i.push(c[l>>2]|0);else for(;l<u;l+=4){let A=c[l>>2]|0;a(A,s[l],s[l+1],s[l+2],s[l+3])&&i.push(A)}}neighbors(t,r,n=1/0,o=1/0,i){if(this._pos!==this._boxes.length)throw new Error("Data not yet indexed - call index.finish().");let{_boxes:a,_levelBounds:s,_indices:c,_queue:l,nodeSize:u}=this,A=this.numItems*4,m=u*4,f=[],g=o*o,y=n===1,E=g;for(l.push(a.length-4<<1,0);l.length;){let b=l.ids[0];if(b&1){if(l.pop(),f.push(b>>1),f.length===n)break;continue}l.pop();let x=b>>1,B=x<A,I=Math.min(x+m,SU(x,s));for(let w=x;w<I;w+=4){let S=a[w],v=a[w+1],D=a[w+2],N=a[w+3],L=Math.max(Math.max(S-t,t-D),0),P=Math.max(Math.max(v-r,r-N),0),h=L*L+P*P;if(h>E)continue;let Q=c[w>>2]|0;B?(i===void 0||i(Q))&&(l.push(Q<<1|1,h),y&&h<E&&(E=h)):l.push(Q<<1,h)}}return l.clear(),f}}});var iA,N_=d(()=>{D_();iA=class{flatbush=null;entries=[];clear(){this.flatbush=null,this.entries=[]}insert(t){this.entries.push(t)}finish(){if(this.entries.length===0)this.flatbush=null;else{this.flatbush=new Yc(this.entries.length);for(let t of this.entries)this.flatbush.add(t.minX,t.minY,t.maxX,t.maxY);this.flatbush.finish()}}search(t){return this.flatbush?.search(t.minX,t.minY,t.maxX,t.maxY).map(r=>this.entries[r])??[]}}});function R_({model:e,offsetY:t}){let r=(0,aA.useRef)(null);r.current??=new iA;let n=r.current,[o,i]=(0,aA.useState)();function a(l){let u=l.nativeEvent.offsetX,A=l.nativeEvent.offsetY+t,m=n.search({minX:u,maxX:u+1,minY:A,maxY:A+1});return m.find(f=>!f.branch)??m[0]}function s(l){let u=a(l);i(u?{...u,clientX:l.clientX,clientY:l.clientY}:void 0),e.setHoveredTreeNode(u?.id),e.setMousePos(void 0,u&&!u.branch?e.rowNamesSet.get(u.name):void 0)}function c(){i(void 0),e.setHoveredTreeNode(void 0),e.setMousePos(void 0,void 0)}return{clickMap:n,hovered:o,hitTest:a,onMouseMove:s,onMouseLeave:c}}var aA,L_=d(()=>{aA=p(k(),1);N_()});var Hr,F_,P_,QU,MU,O_,G_=d(()=>{Hr=p(k(),1);$e();F_=p(V(),1),P_=p($(),1);b_();M_();Lu();L_();xi();QU=X()(e=>({tooltip:{position:"fixed",pointerEvents:"none",zIndex:1e4,backgroundColor:e.palette.grey[700],color:e.palette.common.white,padding:"4px 8px",borderRadius:4,fontSize:12,whiteSpace:"nowrap",maxWidth:300,overflow:"hidden",textOverflow:"ellipsis"},hover:{position:"absolute",pointerEvents:"none",zIndex:100,background:"rgba(0,0,0,0.1)"}})),MU=(0,P_.observer)(function({model:e,offsetY:t}){let{classes:r}=QU(),n=(0,F_.useTheme)(),[o,i]=(0,Hr.useState)(),[a,s]=(0,Hr.useState)(),{clickMap:c,hovered:l,hitTest:u,onMouseMove:A,onMouseLeave:m}=R_({model:e,offsetY:t}),{scrollY:f,treeAreaWidth:g,blockSize:y,highResScaleFactor:E}=e,b=g+Nu,x=y,B=wr(w=>{w.resetTransform(),w.clearRect(0,0,b*E,x*E),Ru({ctx:w,model:e,offsetY:t,clickMap:c,theme:n})},[e,c,t,n]),I={width:b,height:x,top:f+t,left:0,position:"absolute"};return Hr.default.createElement(Hr.default.Fragment,null,o?Hr.default.createElement(E_,{node:o,model:e,onClose:()=>{i(void 0)}}):null,a?Hr.default.createElement(Q_,{node:a,model:e,onClose:()=>{s(void 0)}}):null,Hr.default.createElement("canvas",{ref:B,width:b*E,height:x*E,style:{...I,cursor:l?"pointer":"default"},onMouseMove:w=>{A(w)},onMouseLeave:()=>{m()},onClick:w=>{let S=u(w);if(S){let v={x:w.clientX,y:w.clientY,id:S.id,name:S.name};S.branch?i(v):s(v)}}}),l&&!l.branch?Hr.default.createElement("div",{className:r.hover,style:{left:l.minX,top:l.minY+f,width:l.maxX-l.minX,height:l.maxY-l.minY}}):null,l?Hr.default.createElement("div",{className:r.tooltip,style:{left:l.clientX+12,top:l.clientY+12}},l.name):null)}),O_=MU});var Qo,U_,H_,_U,V_,j_=d(()=>{Qo=p(k(),1),U_=p(Vt(),1),H_=p($(),1);G_();Lu();xi();Gu();a0();_U=(0,H_.observer)(function({model:e}){let t=(0,Qo.useRef)(null),{treeWidth:r,height:n,blocksY:o,treeAreaWidth:i}=e,a=(0,Qo.useCallback)(u=>{e.doScrollY(u)},[e]),{onMouseDown:s,onMouseUp:c}=Ba({ref:t,onScrollY:a}),l=wr(u=>{if((0,U_.isAlive)(e)){let{rowHeight:A,treeAreaWidth:m,height:f,scrollY:g,mouseRow:y,referenceRowIndex:E,hoveredRowIndices:b}=e;u.resetTransform(),u.clearRect(0,0,m,f);let x=B=>{u.fillRect(0,B*A+g,m,A)};E!==void 0&&(u.fillStyle=oA,x(E)),u.fillStyle=a_;for(let B of b)x(B);y!==void 0&&y!==E&&!b.includes(y)&&x(y)}},[e]);return Qo.default.createElement("div",{ref:t,onMouseDown:s,onMouseUp:c,onMouseLeave:u=>{u.preventDefault()},style:{height:n,position:"relative",width:r+Nu}},o.map(u=>Qo.default.createElement(O_,{key:u,model:e,offsetY:u})),Qo.default.createElement("canvas",{ref:l,width:i,height:n,style:{position:"absolute",top:0,left:0,width:i,height:n,zIndex:1e3,pointerEvents:"none"}}))}),V_=_U});var c0,Y_,kU,$_,q_=d(()=>{c0=p(k(),1),Y_=p($(),1);j_();kU=(0,Y_.observer)(function({model:e}){let{treeAreaWidth:t}=e;return c0.default.createElement("div",{style:{overflow:"hidden",flexShrink:0,width:t}},c0.default.createElement(V_,{model:e}))}),$_=kU});var J_,W_,DU,z_,K_=d(()=>{J_=p(k(),1),W_=p($(),1),DU=(0,W_.observer)(({model:e})=>{let{treeAreaWidth:t}=e;return J_.default.createElement("div",{style:{flexShrink:0,width:t}})}),z_=DU});var ce,Ei,NU,RU,LU,FU,PU,OU,X_,Z_=d(()=>{ce=p(k(),1),Ei=p($(),1);Tp();hw();Ew();kM();RM();y_();q_();K_();NU=(0,Ei.observer)(function({model:e}){let{showHorizontalScrollbar:t}=e;return ce.default.createElement("div",{style:{display:"flex"}},ce.default.createElement(z_,{model:e}),t?ce.default.createElement(NM,{model:e}):null)}),RU=(0,Ei.observer)(function({model:e}){let{mouseCol:t,mouseClickCol:r,colWidth:n,scrollX:o,treeAreaWidth:i,resizeHandleWidth:a,totalTrackAreaHeight:s,msaAreaWidth:c,verticalScrollbarWidth:l}=e,u=i+a,A=c-l;return ce.default.createElement("div",{style:{position:"absolute",left:u,top:0,width:A,height:s,overflow:"hidden",pointerEvents:"none"}},t!==void 0?ce.default.createElement("div",{style:{position:"absolute",left:t*n+o,top:0,width:n,height:s,backgroundColor:"rgba(0,0,0,0.15)",zIndex:100}}):null,r!==void 0?ce.default.createElement("div",{style:{position:"absolute",left:r*n+o,top:0,width:n,height:s,backgroundColor:"rgba(128,128,0,0.2)",zIndex:100}}):null)}),LU=(0,Ei.observer)(function({model:e}){let{turnedOnTracks:t}=e;return t.length===0?null:ce.default.createElement("div",{style:{position:"relative"}},ce.default.createElement(RU,{model:e}),t.map(r=>ce.default.createElement(gw,{key:r.model.id,model:e,track:r})))}),FU=(0,Ei.observer)(function({model:e}){let{showVerticalScrollbar:t}=e;return ce.default.createElement("div",{style:{display:"flex"}},ce.default.createElement($_,{model:e}),ce.default.createElement(GI,{model:e}),ce.default.createElement(C_,{model:e}),t?ce.default.createElement(xw,{model:e}):null)}),PU=(0,Ei.observer)(function({model:e}){return ce.default.createElement("div",{style:{position:"relative"}},ce.default.createElement(NU,{model:e}),ce.default.createElement(LU,{model:e}),ce.default.createElement(FU,{model:e}))}),OU=(0,Ei.observer)(function({model:e}){let{height:t,viewInitialized:r,DialogComponent:n,DialogProps:o}=e;return ce.default.createElement("div",null,r?ce.default.createElement(ce.default.Fragment,null,ce.default.createElement("div",{style:{height:t,overflow:"hidden"}},ce.default.createElement(_M,{model:e}),ce.default.createElement(PU,{model:e})),ce.default.createElement(UI,{model:e}),n?ce.default.createElement(ce.Suspense,{fallback:null},ce.default.createElement(n,{...o})):null):null)}),X_=OU});var ek,tk,rk,nk=d(()=>{ek=`CLUSTAL O(1.2.3) multiple sequence alignment
 UniProt/Swiss-Prot|P26898|IL2RA_SHEEP      MEPSLLMWRFFVFIVVPGCVTEACHDDPPSLRNA----------MFKVLRYE----VGTM
 UniProt/Swiss-Prot|P01590|IL2RA_MOUSE      MEPRLLMLGFLSLTIVPSCRAELCLYDPPEVPNA----------TFKALSYK----NGTI
 UniProt/Swiss-Prot|P41690|IL2RA_FELCA      MEPSLLLWGILTFVVVHGHVTELCDENPPDIQHA----------TFKALTYK----TGTM
@@ -50,7 +59,7 @@ UniProt/Swiss-Prot|Q8BZM1|GLMN_MOUSE       PLPLRSLLFLQLPLLGVGLNP----------------
 UniProt/Swiss-Prot|P36835|IL2_CAPHI        -----------LLGVGLNPKFLTP------------------------------------
 UniProt/Swiss-Prot|Q7JFM4|IL2_AOTVO        MLKPPLPLRSLLFLQLPLLGVGLNPKFLTPSGNEDIGGKPGTGGDFFLTSTPAGTLDVST
 UniProt/Swiss-Prot|Q29416|IL2_CANFA        --------------LFLQLSLLG-------------------------------------
-`,US=`CLUSTAL O(1.2.4) multiple sequence alignment
+`,tk=`CLUSTAL O(1.2.4) multiple sequence alignment
 
 
 sp|P69905|HBA_HUMAN       MVLSPADKTNVKAAWGKVGAHAGEYGAEALERMFLSFPTTKTYFPHFDLSHGSAQVKGHG	60
@@ -66,16 +75,27 @@ sp|P13786|HBAZ_CAPHI      SKVVAAVGDAVKSIDNVTSALSKLSELHAYVLRVDPVNFKFLSHCLLVTLASHF
 sp|P69905|HBA_HUMAN       AVHASLDKFLASVSTVLTSKYR	142
 sp|P01942|HBA_MOUSE       AVHASLDKFLASVSTVLTSKYR	142
 sp|P13786|HBAZ_CAPHI      DAHAAWDKFLSIVSGVLTEKYR	142
-                           .**: ****: ** ***.***`,HS="(((UniProt/Swiss-Prot|P26898|IL2RA_SHEEP:0.24036,(UniProt/Swiss-Prot|P41690|IL2RA_FELCA:0.17737,(UniProt/Swiss-Prot|P01589|IL2RA_HUMAN:0.03906,UniProt/Swiss-Prot|Q5MNY4|IL2RA_MACMU:0.03787):0.13033):0.04964):0.02189,UniProt/Swiss-Prot|P01590|IL2RA_MOUSE:0.23072):0.06814,(((UniProt/Swiss-Prot|Q95118|IL2RG_BOVIN:0.09600,UniProt/Swiss-Prot|P40321|IL2RG_CANFA:0.09845):0.25333,UniProt/Swiss-Prot|Q29416|IL2_CANFA:-0.35055):0.10231,(UniProt/Swiss-Prot|P26896|IL2RB_RAT:0.33631,UniProt/Swiss-Prot|Q7JFM4|IL2_AOTVO:-0.33631):0.10166):0.01607,(UniProt/Swiss-Prot|Q8BZM1|GLMN_MOUSE:0.32378,UniProt/Swiss-Prot|P36835|IL2_CAPHI:-0.32378):0.09999)"});async function Ol(e,t,r,n){e.setError(void 0),t&&e.setMSAFilehandle(t),r&&e.setTreeFilehandle(r),n&&e.setGFFFilehandle(n)}var Rm=p(()=>{});function qr({onClick:e,model:t,children:r}){return Tt.default.createElement("li",null,Tt.default.createElement(Gl.Link,{onClick:n=>{t.setError(void 0),n.preventDefault(),e()},href:"#"},Tt.default.createElement(Gl.Typography,{component:"span"},r)))}var Tt,Gl,qS,qn,EF,JS,VS=p(()=>{Tt=f(M(),1),Gl=f(O(),1),qS=f(H(),1);jS();Rm();qn="https://jbrowse.org/genomes/multiple_sequence_alignments",EF=(0,qS.observer)(function({model:e}){function t({msa:r,tree:n,gff:o}){(async()=>{try{await Ol(e,r?{uri:r,locationType:"UriLocation"}:void 0,n?{uri:n,locationType:"UriLocation"}:void 0,o?{uri:o,locationType:"UriLocation"}:void 0)}catch(i){console.error(i),e.setError(i)}})()}return Tt.default.createElement("ul",null,Tt.default.createElement(qr,{model:e,onClick:()=>{t({tree:"https://jbrowse.org/genomes/newicktrees/sarscov2phylo.pub.ft.nh"})}},"230k COVID-19 samples (tree only)"),Tt.default.createElement(qr,{model:e,onClick:()=>{e.setData({msa:GS,tree:HS})}},"Small protein MSA+tree"),Tt.default.createElement(qr,{model:e,onClick:()=>{e.setData({msa:US})}},"Small MSA only"),Tt.default.createElement(qr,{model:e,onClick:()=>{t({msa:`${qn}/pfam-cov2.stock`})}},"PFAM SARS-CoV2 multi-stockholm"),Tt.default.createElement(qr,{model:e,onClick:()=>{t({msa:`${qn}/pfam-cov2.stock`,gff:`${qn}/pfam-cov2-domains.gff`})}},"PFAM SARS-CoV2 multi-stockholm w/ domains loaded"),Tt.default.createElement(qr,{model:e,onClick:()=>{t({msa:`${qn}/Lysine.stock`})}},"Lysine stockholm file"),Tt.default.createElement(qr,{model:e,onClick:()=>{t({msa:`${qn}/PF01601_full.txt`})}},"PF01601 stockholm file (SARS-CoV2 spike protein)"),Tt.default.createElement(qr,{model:e,onClick:()=>{t({msa:`${qn}/europe_covid.fa`})}},"Europe COVID full genomes (LR883044.1 and 199 other sequences)"),Tt.default.createElement(qr,{model:e,onClick:()=>{t({msa:`${qn}/rhv_test-only.aligned_with_mafft_auto.fa`,tree:`${qn}/rhv_test-only.aligned_with_mafft_auto.nh`})}},"MAFFT+VeryFastTree(17.9k samples)"),Tt.default.createElement(qr,{model:e,onClick:()=>{t({msa:"https://jbrowse.org/demos/ttc39a.mfa"})}},"Human BLAST results mfa"))}),JS=EF});var pe,Ji,Ir,YS,IF,zS,WS=p(()=>{pe=f(M(),1),Ji=f(Ne(),1),Ir=f(O(),1),YS=f(H(),1);VS();Rm();IF=(0,YS.observer)(function({model:e}){let[t,r]=(0,pe.useState)(),[n,o]=(0,pe.useState)(),[i,a]=(0,pe.useState)(),{error:s}=e;return pe.default.createElement(Ir.Container,null,pe.default.createElement("div",{style:{width:"50%"}},s?pe.default.createElement(Ji.ErrorMessage,{error:s}):null,pe.default.createElement(Ir.Typography,null,"Open an MSA file (stockholm or clustal format) and/or a tree file (newick format)."),pe.default.createElement(Ir.Typography,{color:"error"},"Note: you can open up just an MSA or just a tree, both are not required. Some MSA files e.g. stockholm format have an embedded tree also and this is fine, and opening a separate tree file is not required.")),pe.default.createElement("div",{style:{display:"flex",justifyContent:"center",alignItems:"center",gap:40}},pe.default.createElement("div",null,pe.default.createElement("div",null,pe.default.createElement(Ir.Typography,null,"MSA file or URL"),pe.default.createElement(Ji.FileSelector,{location:t,setLocation:r})),pe.default.createElement("div",null,pe.default.createElement(Ir.Typography,null,"Tree file or URL"),pe.default.createElement(Ji.FileSelector,{location:n,setLocation:o})),pe.default.createElement("div",null,pe.default.createElement(Ir.Typography,null,"InterProScan GFF file or URL (optional)"),pe.default.createElement(Ji.FileSelector,{location:i,setLocation:a}))),pe.default.createElement("div",null,pe.default.createElement(Ir.Button,{onClick:()=>{(async()=>{try{await Ol(e,t,n,i)}catch(c){console.error(c),e.setError(c)}})()},variant:"contained",color:"primary",disabled:!t&&!n},"Open")),pe.default.createElement("div",null,pe.default.createElement(Ir.Typography,null,"Examples"),pe.default.createElement(JS,{model:e}))))}),zS=IF});var tt,KS,ls,Ul,$S,xF,yF,Hl,Fm=p(()=>{tt=f(M(),1),KS=f(Ne(),1);wu();ls=f(O(),1),Ul=f(H(),1);OS();WS();$S=(0,Ul.observer)(function({model:e}){let{status:t}=e;return tt.default.createElement("div",{style:{display:"flex",alignItems:"center",gap:12,padding:20}},tt.default.createElement("svg",{width:"24",height:"24",viewBox:"0 0 24 24",xmlns:"http://www.w3.org/2000/svg"},tt.default.createElement("style",null,"@keyframes spinner { to { transform: rotate(360deg); } }"),tt.default.createElement("circle",{cx:"12",cy:"12",r:"10",stroke:"#ccc",strokeWidth:"3",fill:"none"}),tt.default.createElement("path",{d:"M12 2a10 10 0 0 1 10 10",stroke:"#1976d2",strokeWidth:"3",fill:"none",strokeLinecap:"round",style:{animation:"spinner 1s linear infinite",transformOrigin:"center"}})),tt.default.createElement(ls.Typography,{variant:"h6"},t?.msg??"Loading..."),t?.onCancel?tt.default.createElement(ls.Button,{variant:"outlined",size:"small",onClick:()=>t.onCancel?.()},"Cancel"):null)}),xF=(0,Ul.observer)(function({model:e,error:t}){return tt.default.createElement("div",null,tt.default.createElement(KS.ErrorMessage,{error:t}),tt.default.createElement(ls.Button,{variant:"contained",color:"primary",onClick:()=>{e.reset()}},"Return to import form"))}),yF=(0,Ul.observer)(function({model:e}){let{isLoading:t,dataInitialized:r,msaFilehandle:n,treeFilehandle:o}=e,i=!!(n||o);return tt.default.createElement("div",null,tt.default.createElement($o,{FallbackComponent:a=>tt.default.createElement(xF,{model:e,error:a.error})},r?t?tt.default.createElement($S,{model:e}):tt.default.createElement(PS,{model:e}):i||t?tt.default.createElement($S,{model:e}):tt.default.createElement(zS,{model:e})))}),Hl=yF});var ZS=V((BV,XS)=>{XS.exports=JBrowseExports["@jbrowse/core/ui/theme"]});var Pm=V((SV,eQ)=>{eQ.exports=JBrowseExports["@jbrowse/core/util/io"]});var rQ=V((QV,tQ)=>{tQ.exports=JBrowseExports["@jbrowse/core/util/types/mst"]});function Om({mapSize:e,blockSize:t,viewportPos:r,viewportSize:n}){let o=Math.max(0,Math.min(r,e-n)),i=Math.floor(o/t),a=Math.floor((o+n-1)/t),s=[];for(let c=i;c<=a;c++)s.push(c*t);return s}var nQ=p(()=>{});function cQ(e,t){let{W:r=0,L:n=0,V:o=0,I:i=0,M:a=0,A:s=0,F:c=0,C:l=0,H:A=0,P:u=0,R:m=0,K:d=0,Q:g=0,E:C=0,D:y=0,T:I=0,S:E=0,G:b=0,Y:x=0,N:w=0}=e,Q=r+n+o+i+a+s+c+l+A+u+x,S=d+m,k=g+C,N=C+y,_=I+E,v=U=>U/t,L={};return v(Q)>.6&&(L.W=Jn,L.L=Jn,L.V=Jn,L.A=Jn,L.I=Jn,L.M=Jn,L.F=Jn,L.C=Jn),(v(S)>.6||v(d)>.8||v(m)>.8||v(g)>.8)&&(L.K=oQ,L.R=oQ),(v(S)>.6||v(k)>.5||v(C)>.8||v(g)>.8||v(y)>.8)&&(L.E=wF),(v(S)>.6||v(N)>.5||v(d)>.8||v(m)>.8||v(g)>.8)&&(L.D=bF),(v(w)>.5||v(x)>.85)&&(L.N=iQ),(v(S)>.6||v(k)>.6||v(g)>.85||v(C)>.85||v(d)>.85||v(m)>.85)&&(L.Q=iQ),(v(Q)>.6||v(_)>.5||v(E)>.85||v(I)>.85)&&(L.S=aQ,L.T=aQ),v(l)>.85&&(L.C=BF),b>0&&(L.G=SF),u>0&&(L.P=QF),(v(Q)>.6||v(r)>.85||v(x)>.85||v(s)>.85||v(l)>.85||v(u)>.85||v(g)>.85||v(c)>.85||v(A)>.85||v(i)>.85||v(n)>.85||v(a)>.85||v(o)>.85)&&(L.H=sQ,L.Y=sQ),L}var Jn,oQ,wF,bF,iQ,aQ,BF,SF,QF,sQ,lQ=p(()=>{Jn="rgb(128,179,230)",oQ="#d88",wF="rgb(192, 72, 192)",bF="rgb(204, 77, 204)",iQ="#8f8",aQ="rgb(26,204,26)",BF="rgb(240, 128, 128)",SF="rgb(240, 144, 72)",QF="rgb(204, 204, 0)",sQ="rgb(26, 179, 179)"});var As,Gm,vF,MF,Um,AQ=p(()=>{As=f(M(),1),Gm=f(H(),1);Su();Bo();Hs();vF=(0,Gm.observer)(function({model:e,track:t,offsetX:r,trackHeight:n}){let{blockSize:o,scrollX:i,highResScaleFactor:a}=e,s=ar(c=>{let{blockSize:l,colWidth:A,highResScaleFactor:u}=e;c.resetTransform(),c.scale(u,u),c.clearRect(0,0,l,n),c.translate(-r,0),uu({ctx:c,values:fu(e,t.model.id),color:t.model.barColor??"gray",colWidth:A,trackHeight:n,offsetX:r,blockSize:l})},[e,t,r,n]);return As.default.createElement("canvas",{ref:s,height:n*a,width:o*a,style:{position:"absolute",left:i+r,width:o,height:n}})}),MF=(0,Gm.observer)(function({model:e,track:t}){let{blocksX:r,msaAreaWidth:n}=e,o=t.model.height;return As.default.createElement("div",{style:{position:"relative",height:o,width:n,overflow:"hidden"}},r.map(i=>As.default.createElement(vF,{key:i,model:e,track:t,offsetX:i,trackHeight:o})),As.default.createElement(Nh,{model:e}))}),Um=MF});var jl,Hm,_F,TF,uQ,fQ=p(()=>{jl=f(M(),1),Hm=f(H(),1);zo();Bo();_m();Hs();_F=(0,Hm.observer)(function({track:e,model:t,offsetX:r}){let{blockSize:n,scrollX:o,colorScheme:i,rowHeight:a,highResScaleFactor:s}=t,{model:{customColorScheme:c,data:l}}=e,A=c??i,{contrastScheme:u}=Rl(A),m=ar(d=>{let{blockSize:g,bgColor:C,colWidth:y,fontSize:I,rowHeight:E,highResScaleFactor:b}=t;d.resetTransform(),d.scale(b,b),d.clearRect(0,0,g,E),d.translate(-r,0),d.textAlign="center",kr(d,I),du({ctx:d,data:l,colorScheme:A,contrastScheme:u,bgColor:C,colWidth:y,rowHeight:E,offsetX:r,blockSize:g})},[t,r,u,A,l]);return jl.default.createElement("canvas",{ref:m,height:a*s,width:n*s,style:{position:"absolute",left:o+r,width:n,height:a}})}),TF=(0,Hm.observer)(function({track:e,model:t}){let{blocksX:r,msaAreaWidth:n,rowHeight:o}=t;return e.model.data?jl.default.createElement("div",{style:{position:"relative",height:o,width:n,overflow:"hidden"}},r.map(i=>jl.default.createElement(_F,{key:i,track:e,model:t,offsetX:i}))):null}),uQ=TF});var kF,jm,dQ=p(()=>{kF=[["#F8766D"],["#F8766D","#00BFC4"],["#F8766D","#00BA38","#619CFF"],["#F8766D","#7CAE00","#00BFC4","#C77CFF"],["#F8766D","#A3A500","#00BF7D","#00B0F6","#E76BF3"],["#F8766D","#B79F00","#00BA38","#00BFC4","#619CFF","#F564E3"],["#F8766D","#C49A00","#53B400","#00C094","#00B6EB","#A58AFF","#FB61D7"],["#F8766D","#CD9600","#7CAE00","#00BE67","#00BFC4","#00A9FF","#C77CFF","#FF61CC"]],jm=kF});function mQ(e){let t=e.length;if(t<=jm.length){let r=jm[t-1];return Object.fromEntries(e.map((n,o)=>[n,r[o]]))}return Object.fromEntries(e.map((r,n)=>[r,Je({h:n*360/t,s:60,l:60}).toHex()]))}var pQ=p(()=>{la();dQ()});function gQ(e){let t=new Map(e.map(n=>[n.id,{id:`${n.id}`,name:`${n.id}`,parent:n.parent!==void 0?`${n.parent}`:void 0,children:[]}])),r;for(let n of e){let o=t.get(n.id),i=n.parent!==void 0?t.get(n.parent):void 0;i?i.children.push(o):r??=o}if(r===void 0)throw new Error("could not build tree from flat node list: no root found (input was empty or contains a parent cycle)");return r}var hQ=p(()=>{});function CQ(e,t){qm||(qm=document.createElement("canvas"));let r=qm.getContext("2d");if(!r)throw new Error("no canvas context");return kr(r,t),r.measureText(e).width}var qm,EQ=p(()=>{zo()});function IQ(){return Jr.types.model({tree:Jr.types.maybe(Jr.types.string),msa:Jr.types.maybe(Jr.types.string),treeMetadata:Jr.types.maybe(Jr.types.string),gff:Jr.types.maybe(Jr.types.string)}).actions(e=>({setTree(t){e.tree=t},setMSA(t){e.msa=t},setTreeMetadata(t){e.treeMetadata=t},setGFF(t){e.gff=t}})).postProcessSnapshot(e=>{let{tree:t,msa:r,treeMetadata:n,gff:o}=e,i=5e4;return{tree:t&&t.length>i?void 0:t,msa:r&&r.length>i?void 0:r,treeMetadata:n&&n.length>i?void 0:n,gff:o&&o.length>i?void 0:o}})}var Jr,xQ=p(()=>{Jr=f(Pt(),1)});function wQ(){return yQ.types.model("DialogQueueSessionMixin",{}).volatile(()=>({queueOfDialogs:[]})).views(e=>({get DialogComponent(){return e.queueOfDialogs[0]?.[0]},get DialogProps(){return e.queueOfDialogs[0]?.[1]}})).actions(e=>({removeActiveDialog(){e.queueOfDialogs=e.queueOfDialogs.slice(1)},queueDialog(t){let[r,n]=t(()=>{this.removeActiveDialog()});e.queueOfDialogs=[...e.queueOfDialogs,[r,n]]}}))}var yQ,bQ=p(()=>{yQ=f(Pt(),1)});function BQ(){return Vr.types.model({bgColor:Vr.types.stripDefault(Vr.types.boolean,Dg),colorSchemeName:Vr.types.stripDefault(Vr.types.string,Rs),showColumnStats:Vr.types.stripDefault(Vr.types.boolean,Ng),msaFormat:Vr.types.maybe(Vr.types.enumeration("MSAFormat",DF))}).actions(e=>({setColorSchemeName(t){e.colorSchemeName=t},setBgColor(t){e.bgColor=t},setShowColumnStats(t){e.showColumnStats=t},setMSAFormat(t){e.msaFormat=t}}))}var Vr,DF,SQ=p(()=>{Vr=f(Pt(),1);aa();DF=["stockholm","a3m","fasta","emf","clustal"]});function QQ(){return rt.types.model({drawLabels:rt.types.stripDefault(rt.types.boolean,Lg),labelsAlignRight:rt.types.stripDefault(rt.types.boolean,Rg),treeAreaWidth:rt.types.stripDefault(rt.types.number,Fg),treeWidth:rt.types.stripDefault(rt.types.number,Pg),showBranchLen:rt.types.stripDefault(rt.types.boolean,Og),drawTree:rt.types.stripDefault(rt.types.boolean,Gg),drawNodeBubbles:rt.types.stripDefault(rt.types.boolean,Ug),autoTreeAreaWidth:rt.types.stripDefault(rt.types.boolean,!1)}).actions(e=>({setTreeAreaWidth(t){e.treeAreaWidth=Math.round(t)},setTreeWidth(t){e.treeWidth=Math.round(t)},setLabelsAlignRight(t){e.labelsAlignRight=t},setDrawTree(t){e.drawTree=t},setAutoTreeAreaWidth(t){e.autoTreeAreaWidth=t},setShowBranchLen(t){e.showBranchLen=t},setDrawNodeBubbles(t){e.drawNodeBubbles=t},setDrawLabels(t){e.drawLabels=t}}))}var rt,vQ=p(()=>{rt=f(Pt(),1);aa()});function Jm(e,t){return _Q.get(e.toUpperCase())?.get(t.toUpperCase())??-4}function LF(e,t){if(e.length!==t.length)throw new Error("Sequences must have the same length (aligned)");let r=0,n=0,o=0,i=0;for(let l=0;l<e.length;l++){let A=e[l],u=t[l];if(A==="-"&&u==="-")continue;if(A==="-"||u==="-"){n++;continue}let m=Jm(A,u);o+=m,i+=Math.max(Jm(A,A),Jm(u,u)),A.toUpperCase()===u.toUpperCase()?r++:n++}if(r+n===0||i<=0)return 1;let s=o/i,c=Math.max(.01,Math.min(1,s));return-Math.log(c)}function RF(e){let t=e.length,r=[];for(let n=0;n<t;n++){r[n]=[];for(let o=0;o<t;o++)n===o?r[n][o]=0:o<n?r[n][o]=r[o][n]:r[n][o]=LF(e[n][1],e[o][1])}return r}function FF(e,t){let r=e.length;if(r<2)return{name:t[0]};if(r===2){let s=e[0][1];return{left:{name:t[0]},right:{name:t[1]},leftLength:s/2,rightLength:s/2}}let n=[];for(let s=0;s<r;s++)n[s]=[...e[s]];let o=t.map(s=>({name:s})),i=r;for(;i>2;){let s=[];for(let E=0;E<o.length;E++)o[E]!==void 0&&s.push(E);let c=new Map;for(let E of s){let b=0;for(let x of s)E!==x&&(b+=n[E][x]);c.set(E,b)}let l=1/0,A=-1,u=-1;for(let E=0;E<s.length;E++)for(let b=E+1;b<s.length;b++){let x=s[E],w=s[b],Q=(i-2)*n[x][w]-c.get(x)-c.get(w);Q<l&&(l=Q,A=x,u=w)}let m=n[A][u],d=c.get(A),g=c.get(u),C=m/2+(d-g)/(2*(i-2)),y=m-C;C=Math.max(0,C),y=Math.max(0,y);let I={left:o[A],right:o[u],leftLength:C,rightLength:y};for(let E of s)if(E!==A&&E!==u){let b=(n[A][E]+n[u][E]-m)/2;n[A][E]=Math.max(0,b),n[E][A]=Math.max(0,b)}o[u]=void 0,o[A]=I,i--}let a=[];for(let s=0;s<o.length;s++)o[s]!==void 0&&a.push(s);if(a.length===2){let s=a[0],c=a[1],l=n[s][c];return{left:o[s],right:o[c],leftLength:l/2,rightLength:l/2}}return o[a[0]]}function MQ(e,t){return t===void 0?e:`${e}:${t.toFixed(6)}`}function PF(e){let t=[],r=[e];for(;r.length>0;){let o=r.pop();t.push(o),o.left&&r.push(o.left),o.right&&r.push(o.right)}let n=new Map;for(let o=t.length-1;o>=0;o--){let i=t[o];if(i.name!==void 0&&!i.left&&!i.right)n.set(i,`'${i.name.replaceAll("'","''")}'`);else{let a=i.left?MQ(n.get(i.left),i.leftLength):"",s=i.right?MQ(n.get(i.right),i.rightLength):"";n.set(i,`(${a},${s})`)}}return n.get(e)}function TQ(e){if(e.length<2)throw new Error("Need at least 2 sequences to build a tree");let t=e.map(o=>o[0]),r=RF(e),n=FF(r,t);return PF(n)+";"}var ql,NF,_Q,kQ=p(()=>{ql="ARNDCQEGHILKMFPSTWYVBZX*",NF=[[4,-1,-2,-2,0,-1,-1,0,-2,-1,-1,-1,-1,-2,-1,1,0,-3,-2,0,-2,-1,0,-4],[-1,5,0,-2,-3,1,0,-2,0,-3,-2,2,-1,-3,-2,-1,-1,-3,-2,-3,-1,0,-1,-4],[-2,0,6,1,-3,0,0,0,1,-3,-3,0,-2,-3,-2,1,0,-4,-2,-3,3,0,-1,-4],[-2,-2,1,6,-3,0,2,-1,-1,-3,-4,-1,-3,-3,-1,0,-1,-4,-3,-3,4,1,-1,-4],[0,-3,-3,-3,9,-3,-4,-3,-3,-1,-1,-3,-1,-2,-3,-1,-1,-2,-2,-1,-3,-3,-2,-4],[-1,1,0,0,-3,5,2,-2,0,-3,-2,1,0,-3,-1,0,-1,-2,-1,-2,0,3,-1,-4],[-1,0,0,2,-4,2,5,-2,0,-3,-3,1,-2,-3,-1,0,-1,-3,-2,-2,1,4,-1,-4],[0,-2,0,-1,-3,-2,-2,6,-2,-4,-4,-2,-3,-3,-2,0,-2,-2,-3,-3,-1,-2,-1,-4],[-2,0,1,-1,-3,0,0,-2,8,-3,-3,-1,-2,-1,-2,-1,-2,-2,2,-3,0,0,-1,-4],[-1,-3,-3,-3,-1,-3,-3,-4,-3,4,2,-3,1,0,-3,-2,-1,-3,-1,3,-3,-3,-1,-4],[-1,-2,-3,-4,-1,-2,-3,-4,-3,2,4,-2,2,0,-3,-2,-1,-2,-1,1,-4,-3,-1,-4],[-1,2,0,-1,-3,1,1,-2,-1,-3,-2,5,-1,-3,-1,0,-1,-3,-2,-2,0,1,-1,-4],[-1,-1,-2,-3,-1,0,-2,-3,-2,1,2,-1,5,0,-2,-1,-1,-1,-1,1,-3,-1,-1,-4],[-2,-3,-3,-3,-2,-3,-3,-3,-1,0,0,-3,0,6,-4,-2,-2,1,3,-1,-3,-3,-1,-4],[-1,-2,-2,-1,-3,-1,-1,-2,-2,-3,-3,-1,-2,-4,7,-1,-1,-4,-3,-2,-2,-1,-2,-4],[1,-1,1,0,-1,0,0,0,-1,-2,-2,0,-1,-2,-1,4,1,-3,-2,-2,0,0,0,-4],[0,-1,0,-1,-1,-1,-1,-2,-2,-1,-1,-1,-1,-2,-1,1,5,-2,-2,0,-1,-1,0,-4],[-3,-3,-4,-4,-2,-2,-3,-2,-2,-3,-2,-3,-1,1,-4,-3,-2,11,2,-3,-4,-3,-2,-4],[-2,-2,-2,-3,-2,-1,-2,-3,2,-1,-1,-2,-1,3,-3,-2,-2,2,7,-1,-3,-2,-1,-4],[0,-3,-3,-3,-1,-2,-2,-3,-3,3,1,-2,1,-1,-2,-2,0,-3,-1,4,-3,-2,-1,-4],[-2,-1,3,4,-3,0,1,-1,0,-3,-4,0,-3,-3,-2,0,-1,-4,-3,-3,4,1,-1,-4],[-1,0,0,1,-3,3,4,-2,0,-3,-3,1,-1,-3,-1,0,-1,-3,-2,-2,1,4,-1,-4],[0,-1,-1,-1,-2,-1,-1,-1,-1,-1,-1,-1,-1,-1,-2,0,0,-2,-1,-1,-1,-1,-1,-4],[-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,1]],_Q=new Map;for(let e=0;e<ql.length;e++){let t=new Map;for(let r=0;r<ql.length;r++)t.set(ql[r],NF[e][r]);_Q.set(ql[e],t)}});function Vm(e){let t=[],r=0;for(;r<e.length&&(r=e.indexOf("{",r),r!==-1);){let n=1,o=r+1;for(r++;r<e.length&&n>0;)e[r]==="{"?n++:e[r]==="}"&&n--,r++;n===0&&t.push(e.slice(o,r-1).trim())}return t}function GF(e,t){let r=e.indexOf("{",t);if(r===-1)return;let n=1,o=r+1;for(;o<e.length&&n>0;)e[o]==="{"?n++:e[o]==="}"&&n--,o++;return n===0?e.slice(r+1,o-1).trim():void 0}function DQ(e){let t=e.replace(/\s+/g," ").replace(/\s*{\s*/g,"{").replace(/\s*}\s*/g,"}").replace(/\s*,\s*/g,",").replace(/\s*::\s*=\s*/g,"::=").replace(/^.*?::=/,""),r=UF(t),{fdict:n,nodes:o}=r;if(n===void 0||o===void 0)throw new Error(`invalid BioTreeContainer ASN.1: missing '${n===void 0?"fdict":"nodes"}' section`);let i=Object.fromEntries(Vm(n).flatMap(a=>{let s=HF(a);return s?[[s.id,OF[s.name]||s.name]]:[]}));return Vm(o).flatMap(a=>{let s=jF(a);if(!s)return[];let{features:c=[],...l}=s;return[{...l,...Object.fromEntries(c.map(A=>[i[A.featureid],A.value]))}]})}function UF(e){let t={},r=e.trim();r.startsWith("{")&&r.endsWith("}")&&(r=r.slice(1,-1).trim());let n=0;for(;n<r.length;){for(;n<r.length&&/\s/.test(r[n]);)n++;if(n>=r.length)break;let o=n;for(;n<r.length&&/\w/.test(r[n]);)n++;if(n>=r.length||r[n]!==" "&&r[n]!=="{"){n=r.indexOf(",",n),n=n===-1?r.length:n+1;continue}let i=r.slice(o,n).trim();for(;n<r.length&&/\s/.test(r[n]);)n++;if(n>=r.length||r[n]!=="{"){n=r.indexOf(",",n),n=n===-1?r.length:n+1;continue}let a=1,s=n+1;for(n++;n<r.length&&a>0;)r[n]==="{"?a++:r[n]==="}"&&a--,n++;a===0&&(t[i]=r.slice(s,n-1).trim()),n=r.indexOf(",",n),n=n===-1?r.length:n+1}return t}function HF(e){let t=/id\s+(\d+)/.exec(e),r=/name\s+"((?:[^"\\]|\\.)*)"/s.exec(e);return!t||!r?null:{id:parseInt(t[1],10),name:r[1].replace(/\\"/g,'"').replace(/\\\\/g,"\\")}}function jF(e){let t=/id\s+(\d+)/.exec(e);if(!t)return null;let r=/parent\s+(\d+)/.exec(e),n=e.indexOf("features"),o=n!==-1?GF(e,n):void 0;return{id:parseInt(t[1],10),...r?{parent:parseInt(r[1],10)}:{},features:o?Vm(o).flatMap(i=>{let a=qF(i);return a?[a]:[]}):[]}}function qF(e){let t=/featureid\s+(\d+)/.exec(e),r=/value\s+"((?:[^"\\]|\\.)*)"/s.exec(e);return!t||!r?null:{featureid:parseInt(t[1],10),value:r[1].replace(/\\"/g,'"').replace(/\\\\/g,"\\")}}var OF,NQ=p(()=>{OF={$NODE_COLLAPSED:"collapsed",$NODE_COLOR:"color",$LABEL_BG_COLOR:"color","seq-id":"seqId","seq-title":"seqTitle","align-index":"alignIndex","accession-nbr":"accessionNbr","blast-name":"blastName","common-name":"commonName","leaf-count":"leafCount"}});function RQ(e,t){return e.map((r,n)=>{let o=t[n];if(!o)return 0;let i=0,a={};for(let[l,A]of Object.entries(r)){let u=LQ[l];u&&(a[u]=(a[u]??0)+A,i+=A)}if(i===0)return 0;let s=0;for(let l of Object.values(a)){let A=l/i;s-=A*Math.log2(A)}let c=(o-i)/o;return Math.max(0,1-s/VF)*(1-c)})}var LQ,JF,VF,FQ=p(()=>{LQ={A:"hydrophobic",V:"hydrophobic",L:"hydrophobic",I:"hydrophobic",M:"hydrophobic",C:"hydrophobic",F:"aromatic",W:"aromatic",Y:"aromatic",H:"aromatic",K:"positive",R:"positive",D:"negative",E:"negative",S:"polar",T:"polar",N:"polar",Q:"polar",G:"special",P:"special"},JF=new Set(Object.values(LQ)).size,VF=Math.log2(JF)});function Ym(e,t){let r=0,n=0,o=0,i=e.length;for(;n<i&&e[n]===o;)n++,o++;for(;r<t;)for(r++,o++;n<i&&e[n]===o;)n++,o++;return o}function PQ(e,t){let r=0,n=e.length-1;for(;r<=n;){let i=Math.floor((r+n)/2);if(e[i]===t)return;e[i]<t?r=i+1:n=i-1}return t-r}function YF({seq:e,blanks:t,visibleCol:r}){let n=Ym(t,r),o=e.length;if(n<o&&ua(e[n]))return;let i=0;for(let a=0;a<n&&a<o;a++)ua(e[a])||i++;return n<o?i:void 0}function OQ({rowName:e,visibleCol:t,rowMap:r,blanks:n}){let o=r.get(e);return o!==void 0?YF({seq:o,visibleCol:t,blanks:n}):void 0}var GQ=p(()=>{xn()});function UQ({row:e,seqPos:t}){let r=0,n=0;for(;n<e.length;){if(!ua(e[n])){if(r===t)return n;r++}n++}return t===0?0:n}var HQ=p(()=>{xn()});function jQ(e,t){let r=URL.createObjectURL(e),n=document.createElement("a");n.href=r,n.download=t,n.click(),setTimeout(()=>{URL.revokeObjectURL(r)},4e4)}var qQ=p(()=>{});function r5(e){return e.startsWith("BioTreeContainer")?gQ(DQ(e)):xo(e.startsWith("SEQ")?dl(e).tree:e)}function n5(){return G.types.compose(wQ(),QQ(),BQ(),G.types.model("MsaView",{id:Qo.ElementId,showDomains:G.types.stripDefault(G.types.boolean,!1),hideGaps:G.types.stripDefault(G.types.boolean,!0),allowedGappyness:G.types.stripDefault(G.types.number,100),subFeatureRows:G.types.stripDefault(G.types.boolean,!1),type:G.types.literal("MsaView"),drawMsaLetters:G.types.stripDefault(G.types.boolean,Tg),scrollZoom:G.types.stripDefault(G.types.boolean,kg),height:G.types.stripDefault(G.types.number,550),rowHeight:G.types.stripDefault(G.types.number,16),scrollY:G.types.stripDefault(G.types.number,0),scrollX:G.types.stripDefault(G.types.number,0),colWidth:G.types.stripDefault(G.types.number,12),treeFilehandle:G.types.maybe(Qo.FileLocation),msaFilehandle:G.types.maybe(Qo.FileLocation),treeMetadataFilehandle:G.types.maybe(Qo.FileLocation),gffFilehandle:G.types.maybe(Qo.FileLocation),currentAlignment:G.types.stripDefault(G.types.number,0),collapsed:G.types.stripDefault(G.types.array(G.types.string),[]),showOnly:G.types.maybe(G.types.string),turnedOffTracks:G.types.stripDefault(G.types.map(G.types.boolean),{}),data:G.types.optional(IQ(),{tree:"",msa:"",treeMetadata:""}),featureFilters:G.types.stripDefault(G.types.map(G.types.boolean),{}),relativeTo:G.types.maybe(G.types.string),highlightColumns:G.types.frozen()})).volatile(()=>({headerHeight:0,status:void 0,highResScaleFactor:typeof window>"u"?1:window.devicePixelRatio,loadingMSA:!1,loadingTree:!1,volatileWidth:void 0,resizeHandleWidth:5,blockSize:500,mouseRow:void 0,mouseCol:void 0,mouseClickRow:void 0,mouseClickCol:void 0,hoveredTreeNode:void 0,highlightedColumns:void 0,minimapHeight:56,conservationTrackHeight:40,marginLeft:20,error:void 0,interProAnnotations:void 0})).actions(e=>({drawRelativeTo(t){e.relativeTo=t},setHideGaps(t){e.hideGaps=t},setAllowedGappyness(t){e.allowedGappyness=t},setLoadingMSA(t){e.loadingMSA=t},setLoadingTree(t){e.loadingTree=t},setWidth(t){e.volatileWidth=t},setHighResScaleFactor(t){e.highResScaleFactor=t},setHeight(t){e.height=t},setError(t){e.error=t},setMousePos(t,r){e.mouseCol=t,e.mouseRow=r},setHighlightedColumns(t){e.highlightedColumns=t},setShowDomains(t){e.showDomains=t},setSubFeatureRows(t){e.subFeatureRows=t},setMouseClickPos(t,r){e.mouseClickCol=t,e.mouseClickRow=r},setRowHeight(t){e.rowHeight=t},setColWidth(t){e.colWidth=t},setScrollY(t){e.scrollY=t},setCurrentAlignment(t){e.currentAlignment=t},toggleCollapsed(t){e.collapsed.includes(t)?e.collapsed.remove(t):e.collapsed.push(t)},setShowOnly(t){e.showOnly=t},setData(t){e.data=(0,G.cast)(t)},setMSAFilehandle(t){e.msaFilehandle=t},setTreeFilehandle(t){e.treeFilehandle=t},setGFFFilehandle(t){e.gffFilehandle=t},setMSA(t){e.data.setMSA(t)},setTree(t){e.data.setTree(t)},setTreeMetadata(t){e.data.setTreeMetadata(t)}})).views(e=>({get hideGapsEffective(){return e.hideGaps&&(e.collapsed.length>0||e.allowedGappyness<100)},get realAllowedGappyness(){return this.hideGapsEffective?e.allowedGappyness:100},get actuallyShowDomains(){return e.showDomains&&!!e.interProAnnotations},get viewInitialized(){return e.volatileWidth!==void 0},get width(){if(e.volatileWidth===void 0)throw new Error("not initialized");return e.volatileWidth}})).views(e=>({extraViewMenuItems(){return[]},get colorScheme(){return za[e.colorSchemeName]??za[Rs]},get header(){return this.MSA?.getHeader()??{}},get alignmentNames(){return this.MSA?.alignmentNames??[]},get noTree(){return!!this.tree.noTree},get noDomains(){return!e.interProAnnotations},menuItems(){return[]},get treeMetadata(){return e.data.treeMetadata?JSON.parse(e.data.treeMetadata):{}},get MSA(){let t=e.data.msa;return t?nm(t,e.currentAlignment,e.msaFormat):null},get numColumns(){return(this.MSA?.getWidth()??0)-this.blanks.length},get tree(){let t=e.data.tree;return t?Ri(r5(t)):this.MSA?.getTree()??{noTree:!0,children:[],id:"empty",name:"empty"}},get rowNames(){return this.leaves.map(t=>t.data.name)},get rowNamesSet(){return new Map(this.leaves.map((t,r)=>[t.data.name,r]))},get mouseOverRowName(){let{mouseRow:t}=e;return t===void 0?void 0:this.leaves[t]?.data.name},get hoveredInsertion(){let{mouseCol:t,mouseRow:r}=e;if(t!==void 0&&r!==void 0){let n=this.leaves[r]?.data.name;if(n){let o=this.insertionPositions.get(n)?.find(i=>i.pos===t);if(o)return{rowName:n,col:t,letters:o.letters}}}},get root(){let t=ih(this.tree,r=>r.children);if(ah(t,r=>r.children.length>0?0:1),sh(t,(r,n)=>(r.data.length??1)-(n.data.length??1)),e.showOnly){let r=js(t,n=>n.data.id===e.showOnly);r&&(t=r)}for(let r of e.collapsed){let n=js(t,o=>o.data.id===r);n&&(n.children?Ah(n):n.parent?.children&&(n.parent.children=n.parent.children.filter(o=>o.data.id!==r)))}return t},get msaAreaWidth(){return e.width-e.treeAreaWidth-e.resizeHandleWidth},get treeAreaWidthMinusMargin(){return e.treeAreaWidth-e.marginLeft},get blanks(){let{hideGapsEffective:t,realAllowedGappyness:r}=e;if(!t)return[];let n=this.leaves.map(l=>this.MSA?.getRow(l.data.name)).filter(Ye.notEmpty);if(n.length===0)return[];let o=n[0].length,i=n.length,a=Math.ceil(r/100*i),s=new Uint16Array(o);for(let l=0;l<i;l++){let A=n[l];for(let u=0;u<o;u++)A.charCodeAt(u)-45>>>0<=1&&s[u]++}let c=[];for(let l=0;l<o;l++)s[l]>=a&&c.push(l);return c},get blanksSet(){return new Set(this.blanks)},get insertionPositions(){let{blanks:t,rows:r}=this;if(t.length===0||!e.hideGapsEffective)return new Map;let n=new Map;for(let[o,i]of r){let a=rh(t,i);a.length>0&&n.set(o,a)}return n},get rows(){let t=this.MSA;return this.leaves.map(r=>[r.data.name,t?.getRow(r.data.name)]).filter(r=>!!r[1])},get numRows(){return this.rows.length},get rowMap(){return new Map(this.rows)},get columns(){let t=this.columns2d;return new Map(this.rows.map((r,n)=>[r[0],t[n]]))},get columns2d(){let{hideGapsEffective:t}=e;return this.rows.map(([,r])=>(t?cu(this.blanks,r):r).toUpperCase())},get fontSize(){return Math.min(Math.max(6,e.rowHeight-3),18)},get colStats(){let t=[],r=this.columns2d;for(let n of r)for(let o=0;o<n.length;o++){let i=t[o]??={},a=n[o];i[a]=(i[a]??0)+1}return t},get colStatsSums(){return this.colStats.map(t=>(0,Ye.sum)(Object.values(t)))},get sequenceType(){let t=new Set;for(let a of this.colStats)for(let s of Object.keys(a))s!=="-"&&s!=="."&&t.add(s);let r=new Set(["A","C","G","T","N"]),n=new Set(["A","C","G","U","N"]),o=t.size>0&&[...t].every(a=>r.has(a)),i=t.size>0&&[...t].every(a=>n.has(a));return o?"dna":i?"rna":"amino"},get colConsensus(){let{colStats:t,colStatsSums:r}=this;return t.map((n,o)=>{let i=r[o];if(!i)return{letter:"",color:void 0};let a=0,s="";for(let[l,A]of Object.entries(n))A>a&&l!=="-"&&l!=="."&&(a=A,s=l);let c=a/i;return{letter:s,color:c>.4?`hsl(240, 30%, ${100*Math.max(1-c/3,.3)}%)`:void 0}})},get colClustalX(){let{colStats:t,colStatsSums:r}=this;return t.map((n,o)=>cQ(n,r[o]))},get conservation(){let{colStats:t,colStatsSums:r,sequenceType:n}=this,i=Math.log2(n==="amino"?20:4);return t.map((a,s)=>{let c=r[s];if(!c)return 0;let l=(a["-"]??0)+(a["."]??0),A=c-l;if(A===0)return 0;let u=0;for(let[g,C]of Object.entries(a))if(g!=="-"&&g!=="."){let y=C/A;u-=y*Math.log2(y)}let m=l/c;return Math.max(0,1-u/i)*(1-m)})},get propertyConservation(){return this.sequenceType==="amino"?RQ(this.colStats,this.colStatsSums):[]},get hierarchy(){let t=this.root;lh(t,this.totalHeight,e.treeWidth),t.data.length=0;let r=dh(t),n=r?e.treeWidth/r:0;return mh(t,0,n),da(t,o=>{if(o._children){let{min:i,max:a}=uh(o);o.collapsedTipXNear=(o.len??0)+i*n,o.collapsedTipXFar=(o.len??0)+a*n}}),t},get totalHeight(){return fa(this.root).length*e.rowHeight},get leaves(){return fa(this.hierarchy)},get maxBranchLength(){return fh(this.hierarchy)},get maxDepthToLeaf(){return ma(this.hierarchy)},get allBranchesLength0(){return ch(this.hierarchy).every(t=>!t.source.data.length)},get showBranchLenEffective(){return this.allBranchesLength0?!1:e.showBranchLen}})).views(e=>({get totalWidth(){return e.numColumns*e.colWidth}})).views(e=>({get dataInitialized(){return(e.data.msa!==""||e.data.tree!=="")&&!e.error},get blocksX(){return Om({viewportSize:e.msaAreaWidth,viewportPos:-e.scrollX,blockSize:e.blockSize,mapSize:e.totalWidth})},get blocksY(){return Om({viewportSize:e.height,viewportPos:-e.scrollY,blockSize:e.blockSize,mapSize:e.totalHeight})}})).views(e=>({get blocks2d(){return e.blocksY.flatMap(t=>e.blocksX.map(r=>[r,t]))},get isLoading(){return e.loadingMSA||e.loadingTree},get maxScrollX(){return Math.min(-e.totalWidth+(e.msaAreaWidth-100),0)},get maxScrollY(){let t=e.height-e.headerHeight-(e.msaAreaWidth<e.totalWidth?e.minimapHeight:0);return Math.min(-e.totalHeight+t,0)},get showMsaLetters(){return e.drawMsaLetters&&e.rowHeight>=5&&e.colWidth>e.rowHeight/2},get showTreeText(){return e.drawLabels&&e.rowHeight>=5}})).actions(e=>({setDrawMsaLetters(t){e.drawMsaLetters=t},setScrollZoom(t){e.scrollZoom=t},setHoveredTreeNode(t){if(t){let r=js(e.hierarchy,n=>n.data.id===t);e.hoveredTreeNode=r?{nodeId:t,descendantNames:fa(r).map(n=>n.data.name)}:void 0}else e.hoveredTreeNode=void 0},calculateNeighborJoiningTreeFromMSA(){if(e.rows.length<2)throw new Error("Need at least 2 sequences to build a tree");let t=TQ(e.rows);e.setTree(t)},resetZoom(){e.setColWidth(12),e.setRowHeight(16)},zoomOutHorizontal(){e.colWidth=Math.max(Ns,Math.floor(e.colWidth*.75)),e.scrollX=(0,Ye.clamp)(e.scrollX,e.maxScrollX,0)},zoomInHorizontal(){e.colWidth=Math.min(to,Math.ceil(e.colWidth*1.5)),e.scrollX=(0,Ye.clamp)(e.scrollX,e.maxScrollX,0)},zoomInVertical(){e.rowHeight=Math.min(to,Math.ceil(e.rowHeight*1.5))},zoomOutVertical(){e.rowHeight=Math.max(Ls,Math.floor(e.rowHeight*.75))},zoomIn(){(0,gt.transaction)(()=>{this.zoomInHorizontal(),this.zoomInVertical()})},zoomOut(){(0,gt.transaction)(()=>{this.zoomOutHorizontal(),this.zoomOutVertical()})},zoomToPos(t,r,n){(0,gt.transaction)(()=>{let o=(-e.scrollX+r)/e.colWidth,i=(-e.scrollY+n)/e.rowHeight;e.colWidth=(0,Ye.clamp)(e.colWidth*t,Ns,to),e.rowHeight=(0,Ye.clamp)(e.rowHeight*t,Ls,to),e.scrollX=(0,Ye.clamp)(r-o*e.colWidth,e.maxScrollX,0);let a=n-i*e.rowHeight,s=Math.max(0,-e.maxScrollY),c=e.totalHeight-s,l=c>0?(0,Ye.clamp)(1-s/c,0,1):1;e.scrollY=(0,Ye.clamp)(a*(1-l),e.maxScrollY,0)})},doScrollY(t){e.scrollY=(0,Ye.clamp)(e.scrollY+t,e.maxScrollY,0)},setDomains(t){e.interProAnnotations=t,e.setShowDomains(!!t)},applyGFFText(t){let r=ml(t);this.setDomains(pl(r))},doScrollX(t){this.setScrollX(e.scrollX+t)},setScrollX(t){e.scrollX=(0,Ye.clamp)(t,e.maxScrollX,0)},toggleTrack(t){e.turnedOffTracks.has(t)?e.turnedOffTracks.delete(t):e.turnedOffTracks.set(t,!0)},setStatus(t){e.status=t}})).views(e=>({get labelWidthMap(){let{rowHeight:t,leaves:r,treeMetadata:n,fontSize:o}=e;return t<=5?new Map:new Map(r.map(i=>{let{name:a}=i.data,s=n[a]?.genome??a;return[a,CQ(s,o)]}))},get labelsWidth(){let t=this.labelWidthMap;return t.size===0?0:Math.max(...t.values())},get secondaryStructureConsensus(){return e.MSA?.secondaryStructureConsensus},get seqConsensus(){return e.MSA?.seqConsensus},get adapterTrackModels(){let{rowHeight:t,MSA:r,hideGapsEffective:n,blanks:o}=e;return(r?.tracks??[]).filter(a=>!!a.data).map(a=>({model:{...a,data:n?cu(o,a.data):a.data,height:t},ReactComponent:uQ}))},get tracks(){let t={model:{id:"conservation",name:"Conservation",height:e.conservationTrackHeight,barColor:"gray"},ReactComponent:Um},r={model:{id:"property-conservation",name:"Property conservation",height:e.conservationTrackHeight,barColor:"#6a51a3"},ReactComponent:Um};return[...this.adapterTrackModels,t,...e.sequenceType==="amino"?[r]:[]]},get turnedOnTracks(){return this.tracks.filter(t=>!e.turnedOffTracks.has(t.model.id))},get showHorizontalScrollbar(){return e.msaAreaWidth<e.totalWidth},visibleColToRowLetter(t,r){let{rowMap:n,blanks:o}=e;return n.get(t)?.[Ym(o,r)]},visibleColToSeqPos(t,r){return OQ({rowName:t,visibleCol:r,rowMap:e.rowMap,blanks:e.blanks})},visibleColToSeqPosOneBased(t,r){let n=this.visibleColToSeqPos(t,r);return n!==void 0?n+1:void 0},globalColToVisibleCol(t){let{blanks:r,hideGapsEffective:n}=e;return n?PQ(r,t):t},seqPosToGlobalCol(t,r){let n=e.rowMap.get(t);return n?UQ({row:n,seqPos:r}):0},seqPosToVisibleCol(t,r){let n=this.seqPosToGlobalCol(t,r);return this.globalColToVisibleCol(n)}})).views(e=>({get msaAreaHeight(){return e.height-(e.showHorizontalScrollbar?e.minimapHeight:0)-e.headerHeight},get totalTrackAreaHeight(){return(0,Ye.sum)(e.turnedOnTracks.map(t=>t.model.height))},get tidyInterProAnnotationTypes(){return new Map(this.tidyInterProAnnotations.map(t=>[t.accession,t]))},get tidyInterProAnnotations(){return e.interProAnnotations?Object.entries(e.interProAnnotations).flatMap(([t,r])=>r.matches.flatMap(({signature:n,locations:o})=>{let{entry:i}=n;return i?o.map(({start:a,end:s,strand:c})=>({id:t,name:i.name,accession:i.accession,description:i.description,featureType:i.featureType,start:a,end:s,strand:c})):[]})).toSorted((t,r)=>lu(r)-lu(t)):[]},get tidyFilteredInterProAnnotations(){return this.tidyInterProAnnotations.filter(t=>e.featureFilters.get(t.accession))},get tidyFilteredGatheredInterProAnnotations(){return(0,Ye.groupBy)(this.tidyFilteredInterProAnnotations,t=>t.id)}})).views(e=>({get showVerticalScrollbar(){return e.msaAreaHeight<e.totalHeight}})).views(e=>({get verticalScrollbarWidth(){return e.showVerticalScrollbar?20:0},get segmentDomainTypes(){return[...e.tidyInterProAnnotationTypes.values()].filter(t=>$A.has(t.featureType??"")).toSorted((t,r)=>t.start-r.start)},get categoricalDomainTypes(){return[...e.tidyInterProAnnotationTypes.values()].filter(t=>!$A.has(t.featureType??""))},get fillPalette(){let t=Object.fromEntries(this.segmentDomainTypes.map((n,o)=>[n.accession,KA[o%KA.length]])),r=mQ(this.categoricalDomainTypes.map(n=>n.accession));return{...t,...r}},get strokePalette(){return Wo(this.fillPalette,([t,r])=>[t,Je(r).darken(.1).toHex()])},get segmentLabels(){return new Map(this.segmentDomainTypes.map((t,r)=>{let n=/(\d+)\s*$/.exec(t.name);return[t.accession,n?n[1]:`${r+1}`]}))},get visibleDomainTypes(){return this.categoricalDomainTypes.filter(t=>e.featureFilters.get(t.accession)).toSorted((t,r)=>t.start-r.start)},get mouseOverDomains(){let{mouseCol:t}=e,r=e.mouseOverRowName;return r!==void 0&&t!==void 0?(e.tidyFilteredGatheredInterProAnnotations[r]??[]).filter(o=>{let i=e.seqPosToVisibleCol(r,o.start-1),a=e.seqPosToVisibleCol(r,o.end);return i!==void 0&&a!==void 0&&t>=i&&t<a}):[]},get mouseOverColumnStats(){let{mouseCol:t}=e;if(t===void 0)return;let r=e.colStats[t],n=e.colStatsSums[t];if(!r||!n)return;let o=(r["-"]??0)+(r["."]??0),i=Object.entries(r).filter(([s])=>s!=="-"&&s!==".").sort((s,c)=>c[1]-s[1]),a=i[0];return{col:t,total:n,gaps:o,gapFraction:o/n,conservation:e.conservation[t]??0,propertyConservation:e.propertyConservation[t],consensusLetter:a?.[0]??"",consensusCount:a?.[1]??0,consensusFraction:a?a[1]/n:0,distribution:i}},getRowData(t){return{data:e.MSA?.getRowData(t),treeMetadata:e.treeMetadata[t]}}})).actions(e=>({setHeaderHeight(t){e.headerHeight=t},setConservationTrackHeight(t){e.conservationTrackHeight=t},reset(){e.setData({tree:"",msa:""}),e.resetZoom(),e.setError(void 0),e.setScrollY(0),e.setScrollX(0),e.setCurrentAlignment(0),e.setTreeFilehandle(void 0),e.setMSAFilehandle(void 0),e.setGFFFilehandle(void 0),e.setDomains(void 0)},async exportSVG(t){let{renderToSvg:r}=await Promise.resolve().then(()=>(yu(),bh)),n=await r(e,t),o=new Blob([n],{type:"image/svg+xml"});jQ(o,"image.svg")},initFilter(t){e.featureFilters.has(t)||e.featureFilters.set(t,!0)},setFilter(t,r){e.featureFilters.set(t,r)},fit(){this.fitVertically(),this.fitHorizontally()},fitVertically(){e.numRows>0&&(e.rowHeight=(0,Ye.clamp)(e.msaAreaHeight/e.numRows,Ls,to)),e.scrollY=0},fitHorizontally(){e.numColumns>0&&(e.colWidth=(0,Ye.clamp)(e.msaAreaWidth/e.numColumns,Ns,to)),e.scrollX=0},afterCreate(){e.highlightColumns?.length&&e.setHighlightedColumns(e.highlightColumns),(0,G.addDisposer)(e,(0,gt.autorun)(()=>{for(let n of e.tidyInterProAnnotationTypes.keys())this.initFilter(n)}));let t=0;(0,G.addDisposer)(e,(0,gt.autorun)(async()=>{let{treeFilehandle:n}=e;if(n){let o=++t;try{e.setLoadingTree(!0);let i=await Wa((0,us.openLocation)(n),a=>{o===t&&e.setStatus(a)});o===t&&(0,gt.transaction)(()=>{e.setTree(i),n.locationType==="BlobLocation"&&e.setTreeFilehandle(void 0)})}catch(i){o===t&&(Dn(i)?e.setTreeFilehandle(void 0):(console.error(i),e.setError(i)))}finally{o===t&&e.setLoadingTree(!1)}}})),(0,G.addDisposer)(e,(0,gt.autorun)(async()=>{let{treeMetadataFilehandle:n}=e;if(n)try{e.setTreeMetadata(await Wa((0,us.openLocation)(n),o=>{e.setStatus(o)}))}catch(o){Dn(o)||(console.error(o),e.setError(o))}})),(0,G.addDisposer)(e,(0,gt.autorun)(()=>{let n=e.data.gff;if(n)try{e.applyGFFText(n)}catch(o){console.error(o),e.setError(o)}})),(0,G.addDisposer)(e,(0,gt.autorun)(async()=>{let{gffFilehandle:n}=e;if(n)try{let o=await Wa((0,us.openLocation)(n),i=>{e.setStatus(i)});e.applyGFFText(o),n.locationType==="BlobLocation"&&e.setGFFFilehandle(void 0)}catch(o){Dn(o)?e.setGFFFilehandle(void 0):(console.error(o),e.setError(o))}}));let r=0;(0,G.addDisposer)(e,(0,gt.autorun)(async()=>{let{msaFilehandle:n}=e;if(n){let o=++r;try{e.setLoadingMSA(!0),e.setError(void 0);let i=await Wa((0,us.openLocation)(n),a=>{o===r&&e.setStatus(a)});o===r&&(0,gt.transaction)(()=>{e.setMSA(i),n.locationType==="BlobLocation"&&e.setMSAFilehandle(void 0)})}catch(i){o===r&&(Dn(i)?e.setMSAFilehandle(void 0):(console.error(i),e.setError(i)))}finally{o===r&&e.setLoadingMSA(!1)}}})),(0,G.addDisposer)(e,(0,gt.autorun)(()=>{e.colorSchemeName.includes("dynamic")&&(e.colStats,e.colStatsSums),e.columns})),(0,G.addDisposer)(e,(0,gt.autorun)(()=>{e.autoTreeAreaWidth&&(e.noTree||!e.drawTree)&&e.labelsWidth&&e.setTreeAreaWidth(e.labelsWidth+e.marginLeft+12)})),(0,G.addDisposer)(e,(0,gt.autorun)(()=>{e.setTreeWidth(Math.max(50,e.treeAreaWidth-e.labelsWidth-10-e.marginLeft))}))}})).postProcessSnapshot(({data:e,...t})=>({...t,data:{...t.treeFilehandle?{}:{tree:e.tree},...t.msaFilehandle?{}:{msa:e.msa},...t.treeMetadataFilehandle?{}:{treeMetadata:e.treeMetadata}}}))}var Ye,us,Qo,G,gt,Jl,zm=p(()=>{Ye=f(de(),1),us=f(Pm(),1),Qo=f(rQ(),1),G=f(Pt(),1);la();gt=f(Vo(),1);im();nQ();lQ();Ud();AQ();fQ();aa();pQ();ul();hQ();pu();EQ();xQ();bQ();SQ();vQ();kQ();NQ();FQ();GQ();HQ();xn();qQ();Jl=n5});var Wm,YQ,o5,DY,zQ=p(()=>{Wm=f(M(),1),YQ=f(ZS(),1),o5=f($u(),1);zm();Fm();DY=(0,YQ.createJBrowseTheme)()});var $m=p(()=>{yu();Fm();zQ();zm()});var zv=V((eW,Yv)=>{Yv.exports=JBrowseExports["@jbrowse/core/data_adapters/BaseAdapter"]});var Kv={};dt(Kv,{default:()=>sA});var Wv,$v,sA,Xv=p(()=>{"use strict";Wv=f(Jo()),$v=f(zv());Vx();sA=class extends $v.BaseAdapter{async configurePre(){let t=this.getSubAdapter;if(t)return(await t({...(0,Wv.readConfObject)(this.config),type:"BgzipFastaAdapter"})).dataAdapter;throw new Error("no get subadapter")}configure(){return this.configureP??=this.configurePre().catch(t=>{throw this.configureP=void 0,t}),this.configureP}async getMSARefs(){return this.refNamesP??=this.configure().then(t=>t.getRefNames()).catch(t=>{throw this.refNamesP=void 0,t}),this.refNamesP}getMsaRegex(){return new RegExp(this.getConf("msaRegex"))}refNameToMsaId(t){return t.split(this.getMsaRegex())[0]}async getMSAList(){let t=await this.getMSARefs();return[...new Set(t.map(n=>this.refNameToMsaId(n)))]}async getMSA(t){let r=await this.configure(),o=(await this.getMSARefs()).filter(i=>this.refNameToMsaId(i)===t);return fd(r.getFeaturesInMultipleRegions(o.map(i=>({refName:i,start:0,end:1e9,assemblyName:""}))).pipe(dd()))}}});var d2=V(f2=>{"use strict";var Wi=M();function V5(e,t){return e===t&&(e!==0||1/e===1/t)||e!==e&&t!==t}var Y5=typeof Object.is=="function"?Object.is:V5,z5=Wi.useState,W5=Wi.useEffect,$5=Wi.useLayoutEffect,K5=Wi.useDebugValue;function X5(e,t){var r=t(),n=z5({inst:{value:r,getSnapshot:t}}),o=n[0].inst,i=n[1];return $5(function(){o.value=r,o.getSnapshot=t,dp(o)&&i({inst:o})},[e,r,t]),W5(function(){return dp(o)&&i({inst:o}),e(function(){dp(o)&&i({inst:o})})},[e]),K5(r),r}function dp(e){var t=e.getSnapshot;e=e.value;try{var r=t();return!Y5(e,r)}catch{return!0}}function Z5(e,t){return t()}var e3=typeof window>"u"||typeof window.document>"u"||typeof window.document.createElement>"u"?Z5:X5;f2.useSyncExternalStore=Wi.useSyncExternalStore!==void 0?Wi.useSyncExternalStore:e3});var p2=V((hW,m2)=>{"use strict";m2.exports=d2()});var rM,nM,oM=p(()=>{"use client";me();rM=f(R(),1),nM=(0,j.createSvgIcon)((0,rM.jsx)("path",{d:"M19 19H5V5h7V3H5c-1.11 0-2 .9-2 2v14c0 1.1.89 2 2 2h14c1.1 0 2-.9 2-2v-7h-2zM14 3v2h3.59l-9.83 9.83 1.41 1.41L19 6.41V10h2V3z"}),"OpenInNew")});function ko(e){let{children:t,...r}=e;return kp.default.createElement(iM.Link,{...r,target:"_blank",rel:"noreferrer"},t," ",kp.default.createElement(nM,{fontSize:"small"}))}var kp,iM,SA=p(()=>{"use strict";kp=f(M());oM();iM=f(O())});var DM=V((OK,kM)=>{kM.exports=JBrowseExports["@jbrowse/core/pluggableElementTypes/ViewType"]});var ys,NM,TA,LM=p(()=>{"use strict";ys=f(M()),NM=f(Ne()),TA=class extends ys.Component{constructor(t){super(t),this.state={hasError:!1,error:null}}static getDerivedStateFromError(t){return{hasError:!0,error:t}}componentDidCatch(t,r){console.error("MsaViewPanel error:",t,r.componentStack)}render(){return this.state.hasError?ys.default.createElement("div",{style:{padding:20}},ys.default.createElement(NM.ErrorMessage,{error:this.state.error})):this.props.children}}});function O3({baseUrl:e,rid:t}){return Up.default.createElement(RM.Typography,null,"RID ",t," (",Up.default.createElement(ko,{href:`${e}?CMD=Get&RID=${t}`},"see status"),")")}var Up,RM,Hp,FM=p(()=>{"use strict";Up=f(M()),RM=f(O());SA();Hp=O3});function G3({baseUrl:e,rid:t,error:r}){return ur.default.createElement("div",null,t?ur.default.createElement(Hp,{rid:t,baseUrl:e}):null,ur.default.createElement(kA.ErrorMessage,{error:r}))}function U3({baseUrl:e,rid:t,progress:r}){let{classes:n}=GM();return ur.default.createElement("div",{className:n.loading},t?ur.default.createElement(Hp,{baseUrl:e,rid:t}):null,ur.default.createElement(jp.Typography,null,r))}var ur,kA,jp,PM,OM,GM,H3,UM,HM=p(()=>{"use strict";ur=f(M()),kA=f(Ne()),jp=f(O()),PM=f(H()),OM=f(wt());FM();GM=(0,OM.makeStyles)()(e=>({margin:{padding:20},loading:{background:e.palette.background.paper}}));H3=(0,PM.observer)(function({model:t,baseUrl:r}){let{progress:n,rid:o,error:i}=t,{classes:a}=GM();return ur.default.createElement("div",{className:a.margin},ur.default.createElement(kA.LoadingEllipses,{message:"Running NCBI BLAST",variant:"h5"}),i?ur.default.createElement(G3,{baseUrl:r,rid:o,error:i}):o?ur.default.createElement(U3,{baseUrl:r,rid:o,progress:n}):ur.default.createElement(jp.Typography,null,n||"Initializing BLAST query"))}),UM=H3});var VM={};dt(VM,{default:()=>J3});var Do,jM,qM,JM,j3,q3,J3,YM=p(()=>{"use strict";Do=f(M()),jM=f(Ne()),qM=f(H());$m();JM=f(wt());LM();HM();j3=(0,JM.makeStyles)()({loadingContainer:{padding:20}}),q3=(0,qM.observer)(function({model:t}){let{classes:r}=j3(),{blastParams:n,loadingStoredData:o}=t;return Do.default.createElement(TA,null,Do.default.createElement("div",null,n?Do.default.createElement(UM,{model:t,baseUrl:n.baseUrl}):o?Do.default.createElement("div",{className:r.loadingContainer},Do.default.createElement(jM.LoadingEllipses,{message:"Loading MSA data",variant:"h6"})):Do.default.createElement(Hl,{model:t})))}),J3=q3});var Y3={};dt(Y3,{default:()=>DA});var KM=f(ug()),Jp=f(Jo()),XM=f(de()),Vp=f(Pt());me();var Cg=f(R(),1),Eg=(0,j.createSvgIcon)((0,Cg.jsx)("path",{d:"M20 2H4c-1.1 0-2 .9-2 2v16c0 1.1.9 2 2 2h16c1.1 0 2-.9 2-2V4c0-1.1-.9-2-2-2M8 20H4v-4h4zm0-6H4v-4h4zm0-6H4V4h4zm6 12h-4v-4h4zm0-6h-4v-4h4zm0-6h-4V4h4zm6 12h-4v-4h4zm0-6h-4v-4h4zm0-6h-4V4h4z"}),"GridOn");var qv=f(M()),Jv=f(de());var ps=f(M()),Hv=f(H());var op=f(M()),Pv=f(de()),ip=f(H());var bg=f(wt());function Zn(e){return!!e&&typeof e=="object"&&"hoverPosition"in e&&!!e.hoverPosition}function wg(e){return/AF-([A-Z0-9]+)-F\d+/.exec(e)?.[1]}var Ts=(0,bg.makeStyles)()({highlight:{height:"100%",background:"rgba(255,255,0,0.2)",border:"1px solid rgba(50,50,0,0.2)",position:"absolute",zIndex:99,textAlign:"center",pointerEvents:"none",overflow:"hidden"}});var Rv=f(YA()),Fv=f(de()),Pe=f(Pt());function Sg(e){let t=e.strand,r=e.refName;if(t!==-1&&t!==1)throw new Error(`Invalid strand value: ${t}. Expected 1 or -1.`);if(!r)throw new Error("refName is required");let n=new Map;for(let c of e.subfeatures??[])if(c.type==="CDS"&&c.start<c.end){let l=`${c.start}-${c.end}`;n.has(l)||n.set(l,c)}let o=[...n.values()].sort((c,l)=>t*(c.start-l.start)),i={},a={},s={};if(o.length!==0){let l=(3-(o[0]?.phase??0))%3,A=-1;for(let u of o){let m=u.end-u.start;for(let d=0;d<m;d++){let g=t===1?u.start+d:u.end-1-d,C=Math.floor(l++/3);i[g]=C,C!==A?(a[C]=g,s[C]=[g],A=C):s[C].push(g)}}}return{g2p:i,p2g:a,p2gCodon:s,refName:r,strand:t}}var aA=f(Vo());$m();var Qv=f(de());function WQ(e,t){let r=e.sciname.replaceAll(" ","_");if(e.taxid&&t?.has(e.taxid)){let n=t.get(e.taxid);n.commonName&&(r=n.commonName.split(" ").map(o=>o.charAt(0).toUpperCase()+o.slice(1).toLowerCase()).join("_"))}return`${e.accession}-${r}`}function $Q(e){return e.replaceAll("-","")}var Yl=f(de());function sr(e){return(0,Yl.getContainingView)(e)}function KQ(e){return[...new Set(e.filter(t=>!!t))]}function XQ(e,t){return t.filter(r=>!!r).join(e)}function i5(e){let r=(e.get("subfeatures")??[]).filter(n=>(n.get("type")==="mRNA"||n.get("type")==="transcript")&&n.get("subfeatures")?.some(o=>o.get("type")==="CDS"));return r.length>0?r:[e]}function Vl(e){let t=(0,Yl.sum)(e.get("subfeatures")?.filter(r=>r.get("type")==="CDS").map(r=>r.get("end")-r.get("start"))??[]);return{len:Math.floor(t/3),mod:t%3}}function vo(e){return e?.id()??""}function a5(e){return e?KQ([e.id(),e.get("name"),e.get("id"),e.get("transcript_id")]):[]}function Vi(e,t){return a5(e).includes(t)}function zl(e){return e?XQ(" ",[e.get("name"),e.get("id")]):""}function Mo(e){return e?XQ(" ",[e.get("gene_name")??e.get("name"),e.get("id")?`(${e.get("id")})`:void 0]):""}function Wl(e,t){return`BLAST - ${Mo(e)} - ${zl(t)}`}function $l(e){return i5(e).toSorted((r,n)=>Vl(n).len-Vl(r).len)}function Kl(e){return e.replaceAll("*","").replaceAll("&","")}function Xl(e){return KQ([e.id(),e.get("id"),e.get("name"),e.get("gene_id"),e.get("gene_name")])}_i();var s5="jbrowse-msaview-blast-cache",Vn="blast-results",c5=2,Km;function Zl(){return Km??=cn(s5,c5,{upgrade(e,t){t<2&&e.objectStoreNames.contains(Vn)&&e.deleteObjectStore(Vn),e.objectStoreNames.contains(Vn)||e.createObjectStore(Vn,{keyPath:"id"})}}).catch(e=>{throw Km=void 0,e}),Km}function l5(e,t,r,n,o){let i=o?`:${o}`:"";return`${t}:${r}:${n}${i}:${e}`}async function ZQ({proteinSequence:e,blastDatabase:t,blastProgram:r,msaAlgorithm:n,msa:o,tree:i,treeMetadata:a,rid:s,geneId:c,transcriptId:l,transcriptName:A,geneName:u}){let m=await Zl(),g={id:l5(e,t,r,n,l),proteinSequence:e,blastDatabase:t,blastProgram:r,msaAlgorithm:n,msa:o,tree:i,treeMetadata:a,rid:s,timestamp:Date.now(),geneId:c,transcriptId:l,transcriptName:A,geneName:u};return await m.put(Vn,g),g}async function ev(){return(await(await Zl()).getAll(Vn)).toSorted((r,n)=>n.timestamp-r.timestamp)}async function tv(e){await(await Zl()).delete(Vn,e)}async function rv(){await(await Zl()).clear(Vn)}async function nv(e,t){let r=await fetch(e,t);if(!r.ok)throw new Error(`HTTP ${r.status} fetching ${e} ${await r.text()}`);return r}async function Yr(e,t){return(await nv(e,t)).text()}async function ov(e,t){return(await nv(e,t)).json()}function iv(e){return new Promise(t=>setTimeout(t,e))}async function eA({check:e,intervalSeconds:t,onCountdown:r}){for(;;){if(await e())return;for(let n=t;n>0;n--)r(n),await iv(1e3)}}var rA="https://www.ebi.ac.uk/Tools/services/rest",tA="colin.diesh@gmail.com",A5={clustalo:{params:{email:tA},msaResult:"aln-clustal_num",treeResult:"phylotree"},muscle:{params:{email:tA,format:"clw",tree:"tree1"},msaResult:"fa",treeResult:"phylotree"},kalign:{params:{email:tA,stype:"protein"},msaResult:"fa",treeResult:"phylotree"},mafft:{params:{email:tA,stype:"protein"},msaResult:"fa",treeResult:"phylotree"}};async function u5({onProgress:e,jobId:t,algorithm:r}){await eA({intervalSeconds:10,onCountdown:n=>{e(`Re-checking MSA status in... ${n}`)},check:async()=>{let n=await Yr(`${rA}/${r}/status/${t}`);if(n.includes("FINISHED"))return!0;if(n.includes("FAILURE"))throw new Error(`Failed to run: jobId ${t}`);return!1}})}async function av({algorithm:e,sequence:t,onProgress:r}){let n=A5[e];r(`Launching ${e} MSA...`);let o=await Yr(`${rA}/${e}/run`,{method:"POST",body:new URLSearchParams({...n.params,sequence:t})});return await u5({jobId:o,algorithm:e,onProgress:r}),{msa:await Yr(`${rA}/${e}/result/${o}/${n.msaResult}`),tree:await Yr(`${rA}/${e}/result/${o}/${n.treeResult}`)}}async function Xm({rid:e,baseUrl:t,onProgress:r}){r(`Checking BLAST status for RID: ${e}...`),await d5({rid:e,onProgress:r,baseUrl:t});let n=await ov(`${t}?CMD=Get&RID=${e}&FORMAT_TYPE=JSON2_S&FORMAT_OBJECT=Alignment`);return{rid:e,hits:n.BlastOutput2[0]?.report.results.search.hits??[]}}async function sv({query:e,blastDatabase:t,blastProgram:r,baseUrl:n,onProgress:o,onRid:i}){o("Submitting to NCBI BLAST...");let{rid:a}=await f5({query:e,blastDatabase:t,blastProgram:r,baseUrl:n});return i(a),Xm({rid:a,baseUrl:n,onProgress:o})}async function f5({query:e,blastProgram:t,blastDatabase:r,baseUrl:n}){let o=await Yr(n,{method:"POST",body:new URLSearchParams({CMD:"Put",PROGRAM:t==="quick-blastp"?"blastp":t,DATABASE:r,QUERY:e,...r==="nr_cluster_seq"?{CLUSTERED_DB:"on",DB_TYPE:"Experimental Databases"}:{},...t==="quick-blastp"?{BLAST_PROGRAMS:"kmerBlastp"}:{}})}),i=/^ {4}RID = (.*$)/m.exec(o)?.[1],a=/^ {4}RTOE = (.*$)/m.exec(o)?.[1];if(!i)throw new Error("Failed to get RID from BLAST request");return{rid:i,rtoe:a}}async function d5({rid:e,onProgress:t,baseUrl:r}){await eA({intervalSeconds:20,onCountdown:n=>{t(`Re-checking BLAST status in... ${n}`)},check:async()=>{let n=await Yr(`${r}?CMD=Get&FORMAT_OBJECT=SearchInfo&RID=${e}`),o=/\s+Status=(\S+)/m.exec(n)?.[1],i=/\s+ThereAreHits=yes/m.test(n);if(o==="WAITING")return!1;if(o==="FAILED")throw new Error(`BLAST ${e} failed`);if(o==="READY"){if(i)return!0;throw new Error("No hits found")}throw new Error(`BLAST ${e} returned unexpected status: ${o??"unknown"}`)}})}_i();var m5="jbrowse-plugin-msaview",p5="colin.diesh@gmail.com",g5="https://eutils.ncbi.nlm.nih.gov/entrez/eutils";function nA(e){let t=new URLSearchParams({...e,tool:m5,email:p5});return`${g5}/efetch.fcgi?${t.toString()}`}var h5="jbrowse-msaview-taxonomy-cache",fs="common-names",C5=2,Zm;function cv(){return Zm??=cn(h5,C5,{upgrade(e){e.objectStoreNames.contains(fs)&&e.deleteObjectStore(fs),e.createObjectStore(fs,{keyPath:"taxid"})}}).catch(e=>{throw Zm=void 0,e}),Zm}async function E5(e){let r=(await cv()).transaction(fs,"readonly"),n=await Promise.all(e.map(o=>r.store.get(o)));return await r.done,n}async function I5(e){let r=(await cv()).transaction(fs,"readwrite");for(let n of e)await r.store.put(n);await r.done}async function lv(e){let t=new Map,r=[],n=await E5(e);for(let a=0;a<e.length;a++){let s=e[a],c=n[a];c?t.set(s,{sciname:c.sciname,commonName:c.commonName}):r.push(s)}if(r.length===0)return t;let o=100,i=[];for(let a=0;a<r.length;a+=o){let s=r.slice(a,a+o),c=s.join(",");try{let A=await(await fetch(nA({db:"taxonomy",id:c,retmode:"xml"}))).text(),u=new Map,m=/<Taxon>\s*<TaxId>(\d+)<\/TaxId>/g,d;for(;(d=m.exec(A))!==null;){let g=Number(d[1]),C=d.index,y=1,I=C+d[0].length;for(;y>0&&I<A.length;){let Q=A.indexOf("<Taxon>",I),S=A.indexOf("</Taxon>",I);if(S===-1)break;Q!==-1&&Q<S?(y++,I=Q+7):(y--,I=S+8)}let E=A.slice(C,I),b=u.get(g),x=E.includes("<LineageEx>"),w=b?.includes("<LineageEx>");(!b||x&&!w)&&u.set(g,E)}for(let g of s){let C=u.get(g);if(C){let y=/<GenbankCommonName>(.*?)<\/GenbankCommonName>/.exec(C),I=/<CommonName>(.*?)<\/CommonName>/.exec(C),E=/<ScientificName>(.*?)<\/ScientificName>/.exec(C),b=y?.[1]??I?.[1],x=E?.[1]??"";t.set(g,{sciname:x,commonName:b}),i.push({taxid:g,sciname:x,commonName:b})}}}catch(l){console.error("Failed to fetch taxonomy data:",l)}}return i.length>0&&await I5(i),t}async function Av({self:e}){let{baseUrl:t,blastDatabase:r,blastProgram:n,msaAlgorithm:o,proteinSequence:i,selectedTranscript:a,rid:s}=e.blastParams,c=Kl(i),l,A;if(s){e.setRid(s);let I=await Xm({rid:s,baseUrl:t,onProgress:E=>{e.setProgress(E)}});l=I.hits,A=I.rid}else{let I=await sv({query:c,blastDatabase:r,blastProgram:n,baseUrl:t,onProgress:E=>{e.setProgress(E)},onRid:E=>{e.setRid(E)}});l=I.hits,A=I.rid}e.setProgress("Fetching species taxonomy info...");let u=l.map(I=>I.description[0]?.taxid).filter(I=>I!==void 0),m=await lv(u),d={},g=l.map(I=>{let E=I.description[0]??{accession:"unknown",id:"unknown",sciname:"unknown"},b=WQ(E,m),x=$Q(I.hsps[0]?.hseq??"");return d[b]=x5(E,m),`>${b}
-${x}`}),C=await av({algorithm:o,sequence:[`>QUERY
+                           .**: ****: ** ***.***`,rk="(((UniProt/Swiss-Prot|P26898|IL2RA_SHEEP:0.24036,(UniProt/Swiss-Prot|P41690|IL2RA_FELCA:0.17737,(UniProt/Swiss-Prot|P01589|IL2RA_HUMAN:0.03906,UniProt/Swiss-Prot|Q5MNY4|IL2RA_MACMU:0.03787):0.13033):0.04964):0.02189,UniProt/Swiss-Prot|P01590|IL2RA_MOUSE:0.23072):0.06814,(((UniProt/Swiss-Prot|Q95118|IL2RG_BOVIN:0.09600,UniProt/Swiss-Prot|P40321|IL2RG_CANFA:0.09845):0.25333,UniProt/Swiss-Prot|Q29416|IL2_CANFA:-0.35055):0.10231,(UniProt/Swiss-Prot|P26896|IL2RB_RAT:0.33631,UniProt/Swiss-Prot|Q7JFM4|IL2_AOTVO:-0.33631):0.10166):0.01607,(UniProt/Swiss-Prot|Q8BZM1|GLMN_MOUSE:0.32378,UniProt/Swiss-Prot|P36835|IL2_CAPHI:-0.32378):0.09999)"});async function sA(e,t,r,n){e.setError(void 0),t&&e.setMSAFilehandle(t),r&&e.setTreeFilehandle(r),n&&e.setGFFFilehandle(n)}var l0=d(()=>{});function En({onClick:e,model:t,children:r}){return Ut.default.createElement("li",null,Ut.default.createElement(cA.Link,{onClick:n=>{t.setError(void 0),n.preventDefault(),e()},href:"#"},Ut.default.createElement(cA.Typography,{component:"span"},r)))}var Ut,cA,ok,Mo,GU,ik,ak=d(()=>{Ut=p(k(),1),cA=p(V(),1),ok=p($(),1);nk();l0();Mo="https://jbrowse.org/genomes/multiple_sequence_alignments",GU=(0,ok.observer)(function({model:e}){function t({msa:r,tree:n,gff:o}){(async()=>{try{await sA(e,r?{uri:r,locationType:"UriLocation"}:void 0,n?{uri:n,locationType:"UriLocation"}:void 0,o?{uri:o,locationType:"UriLocation"}:void 0)}catch(i){console.error(i),e.setError(i)}})()}return Ut.default.createElement("ul",null,Ut.default.createElement(En,{model:e,onClick:()=>{t({tree:"https://jbrowse.org/genomes/newicktrees/sarscov2phylo.pub.ft.nh"})}},"230k COVID-19 samples (tree only)"),Ut.default.createElement(En,{model:e,onClick:()=>{e.setData({msa:ek,tree:rk})}},"Small protein MSA+tree"),Ut.default.createElement(En,{model:e,onClick:()=>{e.setData({msa:tk})}},"Small MSA only"),Ut.default.createElement(En,{model:e,onClick:()=>{t({msa:`${Mo}/pfam-cov2.stock`})}},"PFAM SARS-CoV2 multi-stockholm"),Ut.default.createElement(En,{model:e,onClick:()=>{t({msa:`${Mo}/pfam-cov2.stock`,gff:`${Mo}/pfam-cov2-domains.gff`})}},"PFAM SARS-CoV2 multi-stockholm w/ domains loaded"),Ut.default.createElement(En,{model:e,onClick:()=>{t({msa:`${Mo}/Lysine.stock`})}},"Lysine stockholm file"),Ut.default.createElement(En,{model:e,onClick:()=>{t({msa:`${Mo}/PF01601_full.txt`})}},"PF01601 stockholm file (SARS-CoV2 spike protein)"),Ut.default.createElement(En,{model:e,onClick:()=>{t({msa:`${Mo}/europe_covid.fa`})}},"Europe COVID full genomes (LR883044.1 and 199 other sequences)"),Ut.default.createElement(En,{model:e,onClick:()=>{t({msa:`${Mo}/rhv_test-only.aligned_with_mafft_auto.fa`,tree:`${Mo}/rhv_test-only.aligned_with_mafft_auto.nh`})}},"MAFFT+VeryFastTree(17.9k samples)"),Ut.default.createElement(En,{model:e,onClick:()=>{t({msa:"https://jbrowse.org/demos/ttc39a.mfa"})}},"Human BLAST results mfa"))}),ik=GU});var be,is,Vr,sk,UU,ck,lk=d(()=>{be=p(k(),1),is=p(Ye(),1),Vr=p(V(),1),sk=p($(),1);ak();l0();UU=(0,sk.observer)(function({model:e}){let[t,r]=(0,be.useState)(),[n,o]=(0,be.useState)(),[i,a]=(0,be.useState)(),{error:s}=e;return be.default.createElement(Vr.Container,null,be.default.createElement("div",{style:{width:"50%"}},s?be.default.createElement(is.ErrorMessage,{error:s}):null,be.default.createElement(Vr.Typography,null,"Open an MSA file (stockholm or clustal format) and/or a tree file (newick format)."),be.default.createElement(Vr.Typography,{color:"error"},"Note: you can open up just an MSA or just a tree, both are not required. Some MSA files e.g. stockholm format have an embedded tree also and this is fine, and opening a separate tree file is not required.")),be.default.createElement("div",{style:{display:"flex",justifyContent:"center",alignItems:"center",gap:40}},be.default.createElement("div",null,be.default.createElement("div",null,be.default.createElement(Vr.Typography,null,"MSA file or URL"),be.default.createElement(is.FileSelector,{location:t,setLocation:r})),be.default.createElement("div",null,be.default.createElement(Vr.Typography,null,"Tree file or URL"),be.default.createElement(is.FileSelector,{location:n,setLocation:o})),be.default.createElement("div",null,be.default.createElement(Vr.Typography,null,"InterProScan GFF file or URL (optional)"),be.default.createElement(is.FileSelector,{location:i,setLocation:a}))),be.default.createElement("div",null,be.default.createElement(Vr.Button,{onClick:()=>{(async()=>{try{await sA(e,t,n,i)}catch(c){console.error(c),e.setError(c)}})()},variant:"contained",color:"primary",disabled:!t&&!n},"Open")),be.default.createElement("div",null,be.default.createElement(Vr.Typography,null,"Examples"),be.default.createElement(ik,{model:e}))))}),ck=UU});var ut,fk,$c,lA,uk,HU,VU,uA,u0=d(()=>{ut=p(k(),1),fk=p(Ye(),1);Sp();$c=p(V(),1),lA=p($(),1);Z_();lk();uk=(0,lA.observer)(function({model:e}){let{status:t}=e;return ut.default.createElement("div",{style:{display:"flex",alignItems:"center",gap:12,padding:20}},ut.default.createElement("svg",{width:"24",height:"24",viewBox:"0 0 24 24",xmlns:"http://www.w3.org/2000/svg"},ut.default.createElement("style",null,"@keyframes spinner { to { transform: rotate(360deg); } }"),ut.default.createElement("circle",{cx:"12",cy:"12",r:"10",stroke:"#ccc",strokeWidth:"3",fill:"none"}),ut.default.createElement("path",{d:"M12 2a10 10 0 0 1 10 10",stroke:"#1976d2",strokeWidth:"3",fill:"none",strokeLinecap:"round",style:{animation:"spinner 1s linear infinite",transformOrigin:"center"}})),ut.default.createElement($c.Typography,{variant:"h6"},t?.msg??"Loading..."),t?.onCancel?ut.default.createElement($c.Button,{variant:"outlined",size:"small",onClick:()=>t.onCancel?.()},"Cancel"):null)}),HU=(0,lA.observer)(function({model:e,error:t}){return ut.default.createElement("div",null,ut.default.createElement(fk.ErrorMessage,{error:t}),ut.default.createElement($c.Button,{variant:"contained",color:"primary",onClick:()=>{e.reset()}},"Return to import form"))}),VU=(0,lA.observer)(function({model:e}){let{isLoading:t,dataInitialized:r,msaFilehandle:n,treeFilehandle:o}=e,i=!!(n||o);return ut.default.createElement("div",null,ut.default.createElement(Ia,{FallbackComponent:a=>ut.default.createElement(HU,{model:e,error:a.error})},r?t?ut.default.createElement(uk,{model:e}):ut.default.createElement(X_,{model:e}):i||t?ut.default.createElement(uk,{model:e}):ut.default.createElement(ck,{model:e})))}),uA=VU});var dk=z((ele,Ak)=>{Ak.exports=JBrowseExports["@jbrowse/core/ui/theme"]});var f0=z((tle,mk)=>{mk.exports=JBrowseExports["@jbrowse/core/util/io"]});var gk=z((rle,pk)=>{pk.exports=JBrowseExports["@jbrowse/core/util/types/mst"]});function A0({mapSize:e,blockSize:t,viewportPos:r,viewportSize:n}){let o=Math.max(0,Math.min(r,e-n)),i=Math.floor(o/t),a=Math.floor((o+n-1)/t),s=[];for(let c=i;c<=a;c++)s.push(c*t);return s}var hk=d(()=>{});function bk(e,t){let r=e.total(t),n=G=>e.count(t,G),o=n("W"),i=n("L"),a=n("V"),s=n("I"),c=n("M"),l=n("A"),u=n("F"),A=n("C"),m=n("H"),f=n("P"),g=n("R"),y=n("K"),E=n("Q"),b=n("E"),x=n("D"),B=n("T"),I=n("S"),w=n("G"),S=n("Y"),v=n("N"),D=o+i+a+s+c+l+u+A+m+f+S,N=y+g,L=E+b,P=b+x,h=B+I,Q=G=>G/r,_={};return Q(D)>.6&&(_.W=_o,_.L=_o,_.V=_o,_.A=_o,_.I=_o,_.M=_o,_.F=_o,_.C=_o),(Q(N)>.6||Q(y)>.8||Q(g)>.8||Q(E)>.8)&&(_.K=Ck,_.R=Ck),(Q(N)>.6||Q(L)>.5||Q(b)>.8||Q(E)>.8||Q(x)>.8)&&(_.E=jU),(Q(N)>.6||Q(P)>.5||Q(y)>.8||Q(g)>.8||Q(E)>.8)&&(_.D=YU),(Q(v)>.5||Q(S)>.85)&&(_.N=yk),(Q(N)>.6||Q(L)>.6||Q(E)>.85||Q(b)>.85||Q(y)>.85||Q(g)>.85)&&(_.Q=yk),(Q(D)>.6||Q(h)>.5||Q(I)>.85||Q(B)>.85)&&(_.S=xk,_.T=xk),Q(A)>.85&&(_.C=$U),w>0&&(_.G=qU),f>0&&(_.P=JU),(Q(D)>.6||Q(o)>.85||Q(S)>.85||Q(l)>.85||Q(A)>.85||Q(f)>.85||Q(E)>.85||Q(u)>.85||Q(m)>.85||Q(s)>.85||Q(i)>.85||Q(c)>.85||Q(a)>.85)&&(_.H=Ek,_.Y=Ek),_}var _o,Ck,jU,YU,yk,xk,$U,qU,JU,Ek,Ik=d(()=>{_o="rgb(128,179,230)",Ck="#d88",jU="rgb(192, 72, 192)",YU="rgb(204, 77, 204)",yk="#8f8",xk="rgb(26,204,26)",$U="rgb(240, 128, 128)",qU="rgb(240, 144, 72)",JU="rgb(204, 204, 0)",Ek="rgb(26, 179, 179)"});function fA(e){return e<128?as[e]:30}function wk(e){return e===27||e===28}function Sk(e){return bi[e]}function Bk(e){return fA(e.charCodeAt(0))}function Tk(e){let t=e.reduce((n,o)=>Math.max(n,o.length),0),r=new d0(t);for(let n of e)r.addRow(n);return r}var as,bi,d0,vk,m0=d(()=>{as=new Uint8Array(128).fill(30);for(let e=65;e<=90;e++)as[e]=e-65+1;for(let e=97;e<=122;e++)as[e]=e-97+1;as[45]=27;as[46]=28;as[42]=29;bi=Array.from({length:32},(e,t)=>t>=1&&t<=26?String.fromCharCode(65+t-1):"");bi[27]="-";bi[28]=".";bi[29]="*";bi[30]="?";d0=class{numColumns;counts;totals;slotTotals=new Uint32Array(32);constructor(t){this.numColumns=t,this.counts=new Uint32Array(t*32),this.totals=new Uint32Array(t)}addRow(t){let{counts:r,totals:n,slotTotals:o}=this,i=Math.min(t.length,this.numColumns);for(let a=0;a<i;a++){let s=fA(t.charCodeAt(a));r[a*32+s]++,n[a]++,o[s]++}}add(t,r){let n=fA(r.charCodeAt(0));this.counts[t*32+n]++,this.totals[t]++,this.slotTotals[n]++}total(t){return this.totals[t]??0}count(t,r){return this.counts[t*32+fA(r.charCodeAt(0))]??0}gapCount(t){let r=t*32;return(this.counts[r+27]??0)+(this.counts[r+28]??0)}forEachResidue(t,r){let{counts:n}=this,o=t*32;for(let i=1;i<32;i++){let a=n[o+i];a>0&&!wk(i)&&r(i,a)}}residueEntries(t){let r=[];return this.forEachResidue(t,(n,o)=>{r.push([bi[n],o])}),r}get lettersPresent(){let t=new Set;for(let r=1;r<32;r++)this.slotTotals[r]>0&&!wk(r)&&t.add(bi[r]);return t}};vk=32});var qc,p0,WU,zU,g0,Qk=d(()=>{qc=p(k(),1),p0=p($(),1);Tp();xi();ku();WU=(0,p0.observer)(function({model:e,track:t,offsetX:r,trackHeight:n}){let{blockSize:o,scrollX:i,highResScaleFactor:a}=e,s=wr(c=>{let{blockSize:l,colWidth:u,highResScaleFactor:A}=e;c.resetTransform(),c.scale(A,A),c.clearRect(0,0,l,n),c.translate(-r,0),dp({ctx:c,values:mp(e,t.model.id),color:t.model.barColor??"gray",colWidth:u,trackHeight:n,offsetX:r,blockSize:l})},[e,t,r,n]);return qc.default.createElement("canvas",{ref:s,height:n*a,width:o*a,style:{position:"absolute",left:i+r,width:o,height:n}})}),zU=(0,p0.observer)(function({model:e,track:t}){let{blocksX:r,msaAreaWidth:n}=e,o=t.model.height;return qc.default.createElement("div",{style:{position:"relative",height:o,width:n,overflow:"hidden"}},r.map(i=>qc.default.createElement(WU,{key:i,model:e,track:t,offsetX:i,trackHeight:o})),qc.default.createElement(HI,{model:e}))}),g0=zU});var AA,h0,KU,XU,Mk,_k=d(()=>{AA=p(k(),1),h0=p($(),1);Ea();xi();i0();ku();KU=(0,h0.observer)(function({track:e,model:t,offsetX:r}){let{blockSize:n,scrollX:o,colorScheme:i,rowHeight:a,highResScaleFactor:s}=t,{model:{customColorScheme:c,data:l}}=e,u=c??i,{contrastScheme:A}=nA(u),m=wr(f=>{let{blockSize:g,bgColor:y,colWidth:E,fontSize:b,rowHeight:x,highResScaleFactor:B}=t;f.resetTransform(),f.scale(B,B),f.clearRect(0,0,g,x),f.translate(-r,0),f.textAlign="center",un(f,b),pp({ctx:f,data:l,colorScheme:u,contrastScheme:A,bgColor:y,colWidth:E,rowHeight:x,offsetX:r,blockSize:g})},[t,r,A,u,l]);return AA.default.createElement("canvas",{ref:m,height:a*s,width:n*s,style:{position:"absolute",left:o+r,width:n,height:a}})}),XU=(0,h0.observer)(function({track:e,model:t}){let{blocksX:r,msaAreaWidth:n,rowHeight:o}=t;return e.model.data?AA.default.createElement("div",{style:{position:"relative",height:o,width:n,overflow:"hidden"}},r.map(i=>AA.default.createElement(KU,{key:i,track:e,model:t,offsetX:i}))):null}),Mk=XU});var ZU,C0,kk=d(()=>{ZU=[["#F8766D"],["#F8766D","#00BFC4"],["#F8766D","#00BA38","#619CFF"],["#F8766D","#7CAE00","#00BFC4","#C77CFF"],["#F8766D","#A3A500","#00BF7D","#00B0F6","#E76BF3"],["#F8766D","#B79F00","#00BA38","#00BFC4","#619CFF","#F564E3"],["#F8766D","#C49A00","#53B400","#00C094","#00B6EB","#A58AFF","#FB61D7"],["#F8766D","#CD9600","#7CAE00","#00BE67","#00BFC4","#00A9FF","#C77CFF","#FF61CC"]],C0=ZU});function Dk(e){let t=e.length;if(t<=C0.length){let r=C0[t-1];return Object.fromEntries(e.map((n,o)=>[n,r[o]]))}return Object.fromEntries(e.map((r,n)=>[r,rt({h:n*360/t,s:60,l:60}).toHex()]))}var Nk=d(()=>{rc();kk()});function Rk(e){let t=new Map(e.map(n=>[n.id,{id:`${n.id}`,name:`${n.id}`,parent:n.parent!==void 0?`${n.parent}`:void 0,children:[]}])),r;for(let n of e){let o=t.get(n.id),i=n.parent!==void 0?t.get(n.parent):void 0;i?i.children.push(o):r??=o}if(r===void 0)throw new Error("could not build tree from flat node list: no root found (input was empty or contains a parent cycle)");return r}var Lk=d(()=>{});function Fk(e,t){y0||(y0=document.createElement("canvas"));let r=y0.getContext("2d");if(!r)throw new Error("no canvas context");return un(r,t),r.measureText(e).width}var y0,Pk=d(()=>{Ea()});function Ok(){return bn.types.model({tree:bn.types.maybe(bn.types.string),msa:bn.types.maybe(bn.types.string),treeMetadata:bn.types.maybe(bn.types.string),gff:bn.types.maybe(bn.types.string)}).actions(e=>({setTree(t){e.tree=t},setMSA(t){e.msa=t},setTreeMetadata(t){e.treeMetadata=t},setGFF(t){e.gff=t}})).postProcessSnapshot(e=>{let{tree:t,msa:r,treeMetadata:n,gff:o}=e,i=5e4;return{tree:t&&t.length>i?void 0:t,msa:r&&r.length>i?void 0:r,treeMetadata:n&&n.length>i?void 0:n,gff:o&&o.length>i?void 0:o}})}var bn,Gk=d(()=>{bn=p(Vt(),1)});function Hk(){return Uk.types.model("DialogQueueSessionMixin",{}).volatile(()=>({queueOfDialogs:[]})).views(e=>({get DialogComponent(){return e.queueOfDialogs[0]?.[0]},get DialogProps(){return e.queueOfDialogs[0]?.[1]}})).actions(e=>({removeActiveDialog(){e.queueOfDialogs=e.queueOfDialogs.slice(1)},queueDialog(t){let[r,n]=t(()=>{this.removeActiveDialog()});e.queueOfDialogs=[...e.queueOfDialogs,[r,n]]}}))}var Uk,Vk=d(()=>{Uk=p(Vt(),1)});function pe(e,t){return typeof dA.types.stripDefault=="function"?dA.types.stripDefault(e,t):dA.types.optional(e,t)}var dA,mA=d(()=>{dA=p(Vt(),1)});function jk(){return Ii.types.model({bgColor:pe(Ii.types.boolean,jb),colorSchemeName:pe(Ii.types.string,wu),showColumnStats:pe(Ii.types.boolean,Yb),msaFormat:Ii.types.maybe(Ii.types.enumeration("MSAFormat",e9))}).actions(e=>({setColorSchemeName(t){e.colorSchemeName=t},setBgColor(t){e.bgColor=t},setShowColumnStats(t){e.showColumnStats=t},setMSAFormat(t){e.msaFormat=t}}))}var Ii,e9,Yk=d(()=>{Ii=p(Vt(),1);Zs();mA();e9=["stockholm","a3m","fasta","emf","clustal"]});function $k(){return In.types.model({drawLabels:pe(In.types.boolean,$b),labelsAlignRight:pe(In.types.boolean,qb),treeAreaWidth:pe(In.types.number,Jb),treeWidth:pe(In.types.number,Wb),showBranchLen:pe(In.types.boolean,zb),drawTree:pe(In.types.boolean,Kb),drawNodeBubbles:pe(In.types.boolean,Xb),autoTreeAreaWidth:pe(In.types.boolean,!1)}).actions(e=>({setTreeAreaWidth(t){e.treeAreaWidth=Math.round(t)},setTreeWidth(t){e.treeWidth=Math.round(t)},setLabelsAlignRight(t){e.labelsAlignRight=t},setDrawTree(t){e.drawTree=t},setAutoTreeAreaWidth(t){e.autoTreeAreaWidth=t},setShowBranchLen(t){e.showBranchLen=t},setDrawNodeBubbles(t){e.drawNodeBubbles=t},setDrawLabels(t){e.drawLabels=t}}))}var In,qk=d(()=>{In=p(Vt(),1);Zs();mA()});function x0(e,t){return Wk.get(e.toUpperCase())?.get(t.toUpperCase())??-4}function r9(e,t){if(e.length!==t.length)throw new Error("Sequences must have the same length (aligned)");let r=0,n=0,o=0,i=0;for(let l=0;l<e.length;l++){let u=e[l],A=t[l];if(u==="-"&&A==="-")continue;if(u==="-"||A==="-"){n++;continue}let m=x0(u,A);o+=m,i+=Math.max(x0(u,u),x0(A,A)),u.toUpperCase()===A.toUpperCase()?r++:n++}if(r+n===0||i<=0)return 1;let s=o/i,c=Math.max(.01,Math.min(1,s));return-Math.log(c)}function n9(e){let t=e.length,r=[];for(let n=0;n<t;n++){r[n]=[];for(let o=0;o<t;o++)n===o?r[n][o]=0:o<n?r[n][o]=r[o][n]:r[n][o]=r9(e[n][1],e[o][1])}return r}function o9(e,t){let r=e.length;if(r<2)return{name:t[0]};if(r===2){let s=e[0][1];return{left:{name:t[0]},right:{name:t[1]},leftLength:s/2,rightLength:s/2}}let n=[];for(let s=0;s<r;s++)n[s]=[...e[s]];let o=t.map(s=>({name:s})),i=r;for(;i>2;){let s=[];for(let x=0;x<o.length;x++)o[x]!==void 0&&s.push(x);let c=new Map;for(let x of s){let B=0;for(let I of s)x!==I&&(B+=n[x][I]);c.set(x,B)}let l=1/0,u=-1,A=-1;for(let x=0;x<s.length;x++)for(let B=x+1;B<s.length;B++){let I=s[x],w=s[B],S=(i-2)*n[I][w]-c.get(I)-c.get(w);S<l&&(l=S,u=I,A=w)}let m=n[u][A],f=c.get(u),g=c.get(A),y=m/2+(f-g)/(2*(i-2)),E=m-y;y=Math.max(0,y),E=Math.max(0,E);let b={left:o[u],right:o[A],leftLength:y,rightLength:E};for(let x of s)if(x!==u&&x!==A){let B=(n[u][x]+n[A][x]-m)/2;n[u][x]=Math.max(0,B),n[x][u]=Math.max(0,B)}o[A]=void 0,o[u]=b,i--}let a=[];for(let s=0;s<o.length;s++)o[s]!==void 0&&a.push(s);if(a.length===2){let s=a[0],c=a[1],l=n[s][c];return{left:o[s],right:o[c],leftLength:l/2,rightLength:l/2}}return o[a[0]]}function Jk(e,t){return t===void 0?e:`${e}:${t.toFixed(6)}`}function i9(e){let t=[],r=[e];for(;r.length>0;){let o=r.pop();t.push(o),o.left&&r.push(o.left),o.right&&r.push(o.right)}let n=new Map;for(let o=t.length-1;o>=0;o--){let i=t[o];if(i.name!==void 0&&!i.left&&!i.right)n.set(i,`'${i.name.replaceAll("'","''")}'`);else{let a=i.left?Jk(n.get(i.left),i.leftLength):"",s=i.right?Jk(n.get(i.right),i.rightLength):"";n.set(i,`(${a},${s})`)}}return n.get(e)}function zk(e){if(e.length<2)throw new Error("Need at least 2 sequences to build a tree");let t=e.map(o=>o[0]),r=n9(e),n=o9(r,t);return i9(n)+";"}var pA,t9,Wk,Kk=d(()=>{pA="ARNDCQEGHILKMFPSTWYVBZX*",t9=[[4,-1,-2,-2,0,-1,-1,0,-2,-1,-1,-1,-1,-2,-1,1,0,-3,-2,0,-2,-1,0,-4],[-1,5,0,-2,-3,1,0,-2,0,-3,-2,2,-1,-3,-2,-1,-1,-3,-2,-3,-1,0,-1,-4],[-2,0,6,1,-3,0,0,0,1,-3,-3,0,-2,-3,-2,1,0,-4,-2,-3,3,0,-1,-4],[-2,-2,1,6,-3,0,2,-1,-1,-3,-4,-1,-3,-3,-1,0,-1,-4,-3,-3,4,1,-1,-4],[0,-3,-3,-3,9,-3,-4,-3,-3,-1,-1,-3,-1,-2,-3,-1,-1,-2,-2,-1,-3,-3,-2,-4],[-1,1,0,0,-3,5,2,-2,0,-3,-2,1,0,-3,-1,0,-1,-2,-1,-2,0,3,-1,-4],[-1,0,0,2,-4,2,5,-2,0,-3,-3,1,-2,-3,-1,0,-1,-3,-2,-2,1,4,-1,-4],[0,-2,0,-1,-3,-2,-2,6,-2,-4,-4,-2,-3,-3,-2,0,-2,-2,-3,-3,-1,-2,-1,-4],[-2,0,1,-1,-3,0,0,-2,8,-3,-3,-1,-2,-1,-2,-1,-2,-2,2,-3,0,0,-1,-4],[-1,-3,-3,-3,-1,-3,-3,-4,-3,4,2,-3,1,0,-3,-2,-1,-3,-1,3,-3,-3,-1,-4],[-1,-2,-3,-4,-1,-2,-3,-4,-3,2,4,-2,2,0,-3,-2,-1,-2,-1,1,-4,-3,-1,-4],[-1,2,0,-1,-3,1,1,-2,-1,-3,-2,5,-1,-3,-1,0,-1,-3,-2,-2,0,1,-1,-4],[-1,-1,-2,-3,-1,0,-2,-3,-2,1,2,-1,5,0,-2,-1,-1,-1,-1,1,-3,-1,-1,-4],[-2,-3,-3,-3,-2,-3,-3,-3,-1,0,0,-3,0,6,-4,-2,-2,1,3,-1,-3,-3,-1,-4],[-1,-2,-2,-1,-3,-1,-1,-2,-2,-3,-3,-1,-2,-4,7,-1,-1,-4,-3,-2,-2,-1,-2,-4],[1,-1,1,0,-1,0,0,0,-1,-2,-2,0,-1,-2,-1,4,1,-3,-2,-2,0,0,0,-4],[0,-1,0,-1,-1,-1,-1,-2,-2,-1,-1,-1,-1,-2,-1,1,5,-2,-2,0,-1,-1,0,-4],[-3,-3,-4,-4,-2,-2,-3,-2,-2,-3,-2,-3,-1,1,-4,-3,-2,11,2,-3,-4,-3,-2,-4],[-2,-2,-2,-3,-2,-1,-2,-3,2,-1,-1,-2,-1,3,-3,-2,-2,2,7,-1,-3,-2,-1,-4],[0,-3,-3,-3,-1,-2,-2,-3,-3,3,1,-2,1,-1,-2,-2,0,-3,-1,4,-3,-2,-1,-4],[-2,-1,3,4,-3,0,1,-1,0,-3,-4,0,-3,-3,-2,0,-1,-4,-3,-3,4,1,-1,-4],[-1,0,0,1,-3,3,4,-2,0,-3,-3,1,-1,-3,-1,0,-1,-3,-2,-2,1,4,-1,-4],[0,-1,-1,-1,-2,-1,-1,-1,-1,-1,-1,-1,-1,-1,-2,0,0,-2,-1,-1,-1,-1,-1,-4],[-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,-4,1]],Wk=new Map;for(let e=0;e<pA.length;e++){let t=new Map;for(let r=0;r<pA.length;r++)t.set(pA[r],t9[e][r]);Wk.set(pA[e],t)}});function E0(e){let t=[],r=0;for(;r<e.length&&(r=e.indexOf("{",r),r!==-1);){let n=1,o=r+1;for(r++;r<e.length&&n>0;)e[r]==="{"?n++:e[r]==="}"&&n--,r++;n===0&&t.push(e.slice(o,r-1).trim())}return t}function s9(e,t){let r=e.indexOf("{",t);if(r===-1)return;let n=1,o=r+1;for(;o<e.length&&n>0;)e[o]==="{"?n++:e[o]==="}"&&n--,o++;return n===0?e.slice(r+1,o-1).trim():void 0}function Xk(e){let t=e.replace(/\s+/g," ").replace(/\s*{\s*/g,"{").replace(/\s*}\s*/g,"}").replace(/\s*,\s*/g,",").replace(/\s*::\s*=\s*/g,"::=").replace(/^.*?::=/,""),r=c9(t),{fdict:n,nodes:o}=r;if(n===void 0||o===void 0)throw new Error(`invalid BioTreeContainer ASN.1: missing '${n===void 0?"fdict":"nodes"}' section`);let i=Object.fromEntries(E0(n).flatMap(a=>{let s=l9(a);return s?[[s.id,a9[s.name]||s.name]]:[]}));return E0(o).flatMap(a=>{let s=u9(a);if(!s)return[];let{features:c=[],...l}=s;return[{...l,...Object.fromEntries(c.map(u=>[i[u.featureid],u.value]))}]})}function c9(e){let t={},r=e.trim();r.startsWith("{")&&r.endsWith("}")&&(r=r.slice(1,-1).trim());let n=0;for(;n<r.length;){for(;n<r.length&&/\s/.test(r[n]);)n++;if(n>=r.length)break;let o=n;for(;n<r.length&&/\w/.test(r[n]);)n++;if(n>=r.length||r[n]!==" "&&r[n]!=="{"){n=r.indexOf(",",n),n=n===-1?r.length:n+1;continue}let i=r.slice(o,n).trim();for(;n<r.length&&/\s/.test(r[n]);)n++;if(n>=r.length||r[n]!=="{"){n=r.indexOf(",",n),n=n===-1?r.length:n+1;continue}let a=1,s=n+1;for(n++;n<r.length&&a>0;)r[n]==="{"?a++:r[n]==="}"&&a--,n++;a===0&&(t[i]=r.slice(s,n-1).trim()),n=r.indexOf(",",n),n=n===-1?r.length:n+1}return t}function l9(e){let t=/id\s+(\d+)/.exec(e),r=/name\s+"((?:[^"\\]|\\.)*)"/s.exec(e);return!t||!r?null:{id:parseInt(t[1],10),name:r[1].replace(/\\"/g,'"').replace(/\\\\/g,"\\")}}function u9(e){let t=/id\s+(\d+)/.exec(e);if(!t)return null;let r=/parent\s+(\d+)/.exec(e),n=e.indexOf("features"),o=n!==-1?s9(e,n):void 0;return{id:parseInt(t[1],10),...r?{parent:parseInt(r[1],10)}:{},features:o?E0(o).flatMap(i=>{let a=f9(i);return a?[a]:[]}):[]}}function f9(e){let t=/featureid\s+(\d+)/.exec(e),r=/value\s+"((?:[^"\\]|\\.)*)"/s.exec(e);return!t||!r?null:{featureid:parseInt(t[1],10),value:r[1].replace(/\\"/g,'"').replace(/\\\\/g,"\\")}}var a9,Zk=d(()=>{a9={$NODE_COLLAPSED:"collapsed",$NODE_COLOR:"color",$LABEL_BG_COLOR:"color","seq-id":"seqId","seq-title":"seqTitle","align-index":"alignIndex","accession-nbr":"accessionNbr","blast-name":"blastName","common-name":"commonName","leaf-count":"leafCount"}});function rD(e){let t=new Float64Array(b0.length);return Array.from({length:e.numColumns},(r,n)=>{let o=e.total(n),i=0;if(o){t.fill(0);let a=0;if(e.forEachResidue(n,(s,c)=>{let l=tD[s];l>=0&&(t[l]+=c,a+=c)}),a>0){let s=0;for(let l of t)if(l>0){let u=l/a;s-=u*Math.log2(u)}let c=(o-a)/o;i=Math.max(0,1-s/A9)*(1-c)}}return i})}var eD,b0,A9,tD,nD=d(()=>{m0();eD={A:"hydrophobic",V:"hydrophobic",L:"hydrophobic",I:"hydrophobic",M:"hydrophobic",C:"hydrophobic",F:"aromatic",W:"aromatic",Y:"aromatic",H:"aromatic",K:"positive",R:"positive",D:"negative",E:"negative",S:"polar",T:"polar",N:"polar",Q:"polar",G:"special",P:"special"},b0=[...new Set(Object.values(eD))],A9=Math.log2(b0.length),tD=new Int8Array(vk).fill(-1);for(let[e,t]of Object.entries(eD))tD[Bk(e)]=b0.indexOf(t)});function I0(e,t){let r=0,n=0,o=0,i=e.length;for(;n<i&&e[n]===o;)n++,o++;for(;r<t;)for(r++,o++;n<i&&e[n]===o;)n++,o++;return o}function oD(e,t){let r=0,n=e.length-1;for(;r<=n;){let i=Math.floor((r+n)/2);if(e[i]===t)return;e[i]<t?r=i+1:n=i-1}return t-r}function d9({seq:e,blanks:t,visibleCol:r}){let n=I0(t,r),o=e.length;if(n<o&&Mu(e[n]))return;let i=0;for(let a=0;a<n&&a<o;a++)Mu(e[a])||i++;return n<o?i:void 0}function iD({rowName:e,visibleCol:t,rowMap:r,blanks:n}){let o=r.get(e);return o!==void 0?d9({seq:o,visibleCol:t,blanks:n}):void 0}var aD=d(()=>{so()});function sD(e){let t=new Int32Array(e.length),r=0;for(let n=0;n<e.length;n++)e.charCodeAt(n)-45>>>0<=1||(t[r++]=n);return t.subarray(0,r)}var cD=d(()=>{so()});function lD(e,t){let r=URL.createObjectURL(e),n=document.createElement("a");n.href=r,n.download=t,n.click(),setTimeout(()=>{URL.revokeObjectURL(r)},4e4)}var uD=d(()=>{});function b9(e){return e.startsWith("BioTreeContainer")?Rk(Xk(e)):gi(e.startsWith("SEQ")?Nf(e).tree:e)}function I9(){return K.types.compose(Hk(),$k(),jk(),K.types.model("MsaView",{id:wi.ElementId,showDomains:pe(K.types.boolean,!1),hideGaps:pe(K.types.boolean,!0),allowedGappyness:pe(K.types.number,100),subFeatureRows:pe(K.types.boolean,!1),type:K.types.literal("MsaView"),drawMsaLetters:pe(K.types.boolean,Hb),scrollZoom:pe(K.types.boolean,Vb),height:pe(K.types.number,550),rowHeight:pe(K.types.number,16),scrollY:pe(K.types.number,0),scrollX:pe(K.types.number,0),colWidth:pe(K.types.number,12),treeFilehandle:K.types.maybe(wi.FileLocation),msaFilehandle:K.types.maybe(wi.FileLocation),treeMetadataFilehandle:K.types.maybe(wi.FileLocation),gffFilehandle:K.types.maybe(wi.FileLocation),currentAlignment:pe(K.types.number,0),collapsed:pe(K.types.array(K.types.string),[]),showOnly:K.types.maybe(K.types.string),turnedOffTracks:pe(K.types.map(K.types.boolean),{}),data:K.types.optional(Ok(),{tree:"",msa:"",treeMetadata:""}),featureFilters:pe(K.types.map(K.types.boolean),{}),relativeTo:K.types.maybe(K.types.string),highlightColumns:K.types.frozen()})).volatile(()=>({headerHeight:0,status:void 0,highResScaleFactor:typeof window>"u"?1:window.devicePixelRatio,loadingMSA:!1,loadingTree:!1,volatileWidth:void 0,resizeHandleWidth:5,blockSize:500,mouseRow:void 0,mouseCol:void 0,mouseClickRow:void 0,mouseClickCol:void 0,hoveredTreeNode:void 0,highlightedColumns:void 0,minimapHeight:56,conservationTrackHeight:40,marginLeft:20,error:void 0,interProAnnotations:void 0})).actions(e=>({drawRelativeTo(t){e.relativeTo=t},setHideGaps(t){e.hideGaps=t},setAllowedGappyness(t){e.allowedGappyness=t},setLoadingMSA(t){e.loadingMSA=t},setLoadingTree(t){e.loadingTree=t},setWidth(t){e.volatileWidth=t},setHighResScaleFactor(t){e.highResScaleFactor=t},setHeight(t){e.height=t},setError(t){e.error=t},setMousePos(t,r){e.mouseCol=t,e.mouseRow=r},setHighlightedColumns(t){e.highlightedColumns=t},setShowDomains(t){e.showDomains=t},setSubFeatureRows(t){e.subFeatureRows=t},setMouseClickPos(t,r){e.mouseClickCol=t,e.mouseClickRow=r},setRowHeight(t){e.rowHeight=t},setColWidth(t){e.colWidth=t},setScrollY(t){e.scrollY=t},setCurrentAlignment(t){e.currentAlignment=t},toggleCollapsed(t){e.collapsed.includes(t)?e.collapsed.remove(t):e.collapsed.push(t)},setShowOnly(t){e.showOnly=t},setData(t){e.data=(0,K.cast)(t)},setMSAFilehandle(t){e.msaFilehandle=t},setTreeFilehandle(t){e.treeFilehandle=t},setGFFFilehandle(t){e.gffFilehandle=t},setMSA(t){e.data.setMSA(t)},setTree(t){e.data.setTree(t)},setTreeMetadata(t){e.data.setTreeMetadata(t)}})).views(e=>({get hideGapsEffective(){return e.hideGaps&&(e.collapsed.length>0||e.allowedGappyness<100)},get realAllowedGappyness(){return this.hideGapsEffective?e.allowedGappyness:100},get actuallyShowDomains(){return e.showDomains&&!!e.interProAnnotations},get viewInitialized(){return e.volatileWidth!==void 0},get width(){if(e.volatileWidth===void 0)throw new Error("not initialized");return e.volatileWidth}})).views(e=>({extraViewMenuItems(){return[]},get colorScheme(){return _c[e.colorSchemeName]??_c[wu]},get header(){return this.MSA?.getHeader()??{}},get alignmentNames(){return this.MSA?.alignmentNames??[]},get noTree(){return!!this.tree.noTree},get noDomains(){return!e.interProAnnotations},menuItems(){return[]},get treeMetadata(){return e.data.treeMetadata?JSON.parse(e.data.treeMetadata):{}},get MSA(){let t=e.data.msa;return t?kh(t,e.currentAlignment,e.msaFormat):null},get numColumns(){return(this.MSA?.getWidth()??0)-this.blanks.length},get tree(){let t=e.data.tree;return t?za(b9(t)):this.MSA?.getTree()??{noTree:!0,children:[],id:"empty",name:"empty"}},get rowNames(){return this.leaves.map(t=>t.data.name)},get rowNamesSet(){return new Map(this.leaves.map((t,r)=>[t.data.name,r]))},get mouseOverRowName(){let{mouseRow:t}=e;return t===void 0?void 0:this.leaves[t]?.data.name},get hoveredInsertion(){let{mouseCol:t,mouseRow:r}=e;if(t!==void 0&&r!==void 0){let n=this.leaves[r]?.data.name;if(n){let o=this.insertionPositions.get(n)?.find(i=>i.pos===t);if(o)return{rowName:n,col:t,letters:o.letters}}}},get root(){let t=gI(this.tree,r=>r.children);if(hI(t,r=>r.children.length>0?0:1),CI(t,(r,n)=>(r.data.length??1)-(n.data.length??1)),e.showOnly){let r=Du(t,n=>n.data.id===e.showOnly);r&&(t=r)}for(let r of e.collapsed){let n=Du(t,o=>o.data.id===r);n&&(n.children?EI(n):n.parent?.children&&(n.parent.children=n.parent.children.filter(o=>o.data.id!==r)))}return t},get msaAreaWidth(){return e.width-e.treeAreaWidth-e.resizeHandleWidth},get treeAreaWidthMinusMargin(){return e.treeAreaWidth-e.marginLeft},get blanks(){let{hideGapsEffective:t,realAllowedGappyness:r}=e;if(!t)return[];let n=this.leaves.map(l=>this.MSA?.getRow(l.data.name)).filter(Ze.notEmpty);if(n.length===0)return[];let o=n.reduce((l,u)=>Math.max(l,u.length),0),i=n.length,a=Math.ceil(r/100*i),s=new Uint32Array(o);for(let l=0;l<i;l++){let u=n[l],A=u.length;for(let m=0;m<o;m++)(m>=A||u.charCodeAt(m)-45>>>0<=1)&&s[m]++}let c=[];for(let l=0;l<o;l++)s[l]>=a&&c.push(l);return c},get blanksSet(){return new Set(this.blanks)},get insertionPositions(){let{blanks:t,rows:r}=this;if(t.length===0||!e.hideGapsEffective)return new Map;let n=new Map;for(let[o,i]of r){let a=dI(t,i);a.length>0&&n.set(o,a)}return n},get rows(){let t=this.MSA;return this.leaves.map(r=>[r.data.name,t?.getRow(r.data.name)]).filter(r=>!!r[1])},get numRows(){return this.leaves.length},get seqPosGlobalColIndex(){return new Map(this.rows.map(([t,r])=>[t,sD(r)]))},get rowMap(){return new Map(this.rows)},get columns(){let t=this.columns2d;return new Map(this.rows.map((r,n)=>[r[0],t[n]]))},get columns2d(){let{hideGapsEffective:t}=e;return this.rows.map(([,r])=>(t?up(this.blanks,r):r).toUpperCase())},get fontSize(){return Math.min(Math.max(6,e.rowHeight-3),18)},get colStats(){return Tk(this.columns2d)},get colStatsSums(){return this.colStats.totals},get sequenceType(){let t=this.colStats.lettersPresent,r=new Set(["A","C","G","T","N"]),n=new Set(["A","C","G","U","N"]),o=t.size>0&&[...t].every(a=>r.has(a)),i=t.size>0&&[...t].every(a=>n.has(a));return o?"dna":i?"rna":"amino"},get colConsensus(){let{colStats:t}=this;return Array.from({length:t.numColumns},(r,n)=>{let o=t.total(n),i=0,a="";t.forEachResidue(n,(c,l)=>{l>i&&(i=l,a=Sk(c))});let s=o?i/o:0;return{letter:a,color:s>.4?`hsl(240, 30%, ${100*Math.max(1-s/3,.3)}%)`:void 0}})},get colClustalX(){let{colStats:t}=this;return Array.from({length:t.numColumns},(r,n)=>bk(t,n))},get conservation(){let{colStats:t,sequenceType:r}=this,o=Math.log2(r==="amino"?20:4);return Array.from({length:t.numColumns},(i,a)=>{let s=t.total(a),c=t.gapCount(a),l=s-c,u=0;if(l>0){let A=0;t.forEachResidue(a,(m,f)=>{let g=f/l;A-=g*Math.log2(g)}),u=Math.max(0,1-A/o)*(1-c/s)}return u})},get propertyConservation(){return this.sequenceType==="amino"?rD(this.colStats):[]},get hierarchy(){let t=this.root;xI(t,this.totalHeight,e.treeWidth),t.data.length=0;let r=wI(t),n=r?e.treeWidth/r:0;return SI(t,0,n),ic(t,o=>{if(o._children){let{min:i,max:a}=bI(o);o.collapsedTipXNear=(o.len??0)+i*n,o.collapsedTipXFar=(o.len??0)+a*n}}),t},get totalHeight(){return oc(this.root).length*e.rowHeight},get leaves(){return oc(this.hierarchy)},get maxBranchLength(){return II(this.hierarchy)},get maxDepthToLeaf(){return ac(this.hierarchy)},get allBranchesLength0(){return yI(this.hierarchy).every(t=>!t.source.data.length)},get showBranchLenEffective(){return this.allBranchesLength0?!1:e.showBranchLen}})).views(e=>({get totalWidth(){return e.numColumns*e.colWidth}})).views(e=>({get dataInitialized(){return(e.data.msa!==""||e.data.tree!=="")&&!e.error},get blocksX(){return A0({viewportSize:e.msaAreaWidth,viewportPos:-e.scrollX,blockSize:e.blockSize,mapSize:e.totalWidth})},get blocksY(){return A0({viewportSize:e.height,viewportPos:-e.scrollY,blockSize:e.blockSize,mapSize:e.totalHeight})}})).views(e=>({get blocks2d(){return e.blocksY.flatMap(t=>e.blocksX.map(r=>[r,t]))},get isLoading(){return e.loadingMSA||e.loadingTree},get maxScrollX(){return Math.min(-e.totalWidth+(e.msaAreaWidth-100),0)},get maxScrollY(){let t=e.height-e.headerHeight-(e.msaAreaWidth<e.totalWidth?e.minimapHeight:0);return Math.min(-e.totalHeight+t,0)},get showMsaLetters(){return e.drawMsaLetters&&e.rowHeight>=5&&e.colWidth>e.rowHeight/2},get showTreeText(){return e.drawLabels&&e.rowHeight>=5}})).actions(e=>({setDrawMsaLetters(t){e.drawMsaLetters=t},setScrollZoom(t){e.scrollZoom=t},setHoveredTreeNode(t){if(t){let r=Du(e.hierarchy,n=>n.data.id===t);e.hoveredTreeNode=r?{nodeId:t,descendantNames:oc(r).map(n=>n.data.name)}:void 0}else e.hoveredTreeNode=void 0},calculateNeighborJoiningTreeFromMSA(){if(e.rows.length<2)throw new Error("Need at least 2 sequences to build a tree");let t=zk(e.rows);e.setTree(t)},resetZoom(){e.setColWidth(12),e.setRowHeight(16)},zoomOutHorizontal(){e.colWidth=Math.max(bu,Math.floor(e.colWidth*.75)),e.scrollX=(0,Ze.clamp)(e.scrollX,e.maxScrollX,0)},zoomInHorizontal(){e.colWidth=Math.min(Zo,Math.ceil(e.colWidth*1.5)),e.scrollX=(0,Ze.clamp)(e.scrollX,e.maxScrollX,0)},zoomInVertical(){e.rowHeight=Math.min(Zo,Math.ceil(e.rowHeight*1.5))},zoomOutVertical(){e.rowHeight=Math.max(Iu,Math.floor(e.rowHeight*.75))},zoomIn(){(0,St.transaction)(()=>{this.zoomInHorizontal(),this.zoomInVertical()})},zoomOut(){(0,St.transaction)(()=>{this.zoomOutHorizontal(),this.zoomOutVertical()})},zoomToPos(t,r,n){(0,St.transaction)(()=>{let o=(-e.scrollX+r)/e.colWidth,i=(-e.scrollY+n)/e.rowHeight;e.colWidth=(0,Ze.clamp)(e.colWidth*t,bu,Zo),e.rowHeight=(0,Ze.clamp)(e.rowHeight*t,Iu,Zo),e.scrollX=(0,Ze.clamp)(r-o*e.colWidth,e.maxScrollX,0);let a=n-i*e.rowHeight,s=Math.max(0,-e.maxScrollY),c=e.totalHeight-s,l=c>0?(0,Ze.clamp)(1-s/c,0,1):1;e.scrollY=(0,Ze.clamp)(a*(1-l),e.maxScrollY,0)})},doScrollY(t){e.scrollY=(0,Ze.clamp)(e.scrollY+t,e.maxScrollY,0)},setDomains(t){e.interProAnnotations=t,e.setShowDomains(!!t)},applyGFFText(t){let r=Rf(t);this.setDomains(Lf(r))},doScrollX(t){this.setScrollX(e.scrollX+t)},setScrollX(t){e.scrollX=(0,Ze.clamp)(t,e.maxScrollX,0)},toggleTrack(t){e.turnedOffTracks.has(t)?e.turnedOffTracks.delete(t):e.turnedOffTracks.set(t,!0)},setStatus(t){e.status=t}})).views(e=>({get labelWidthMap(){let{rowHeight:t,leaves:r,treeMetadata:n,fontSize:o}=e;return t<=5?new Map:new Map(r.map(i=>{let{name:a}=i.data,s=n[a]?.genome??a;return[a,Fk(s,o)]}))},get labelsWidth(){let t=this.labelWidthMap;return t.size===0?0:Math.max(...t.values())},get secondaryStructureConsensus(){return e.MSA?.secondaryStructureConsensus},get seqConsensus(){return e.MSA?.seqConsensus},get adapterTrackModels(){let{rowHeight:t,MSA:r,hideGapsEffective:n,blanks:o}=e;return(r?.tracks??[]).filter(a=>!!a.data).map(a=>({model:{...a,data:n?up(o,a.data):a.data,height:t},ReactComponent:Mk}))},get tracks(){let t={model:{id:"conservation",name:"Conservation",height:e.conservationTrackHeight,barColor:"gray"},ReactComponent:g0},r={model:{id:"property-conservation",name:"Property conservation",height:e.conservationTrackHeight,barColor:"#6a51a3"},ReactComponent:g0};return[...this.adapterTrackModels,t,...e.sequenceType==="amino"?[r]:[]]},get turnedOnTracks(){return this.tracks.filter(t=>!e.turnedOffTracks.has(t.model.id))},get showHorizontalScrollbar(){return e.msaAreaWidth<e.totalWidth},visibleColToRowLetter(t,r){let{rowMap:n,blanks:o}=e;return n.get(t)?.[I0(o,r)]},visibleColToSeqPos(t,r){return iD({rowName:t,visibleCol:r,rowMap:e.rowMap,blanks:e.blanks})},visibleColToSeqPosOneBased(t,r){let n=this.visibleColToSeqPos(t,r);return n!==void 0?n+1:void 0},globalColToVisibleCol(t){let{blanks:r,hideGapsEffective:n}=e;return n?oD(r,t):t},seqPosToGlobalCol(t,r){let n=e.rowMap.get(t);return n===void 0?0:e.seqPosGlobalColIndex.get(t)?.[r]??(r===0?0:n.length)},seqPosToVisibleCol(t,r){let n=this.seqPosToGlobalCol(t,r);return this.globalColToVisibleCol(n)}})).views(e=>({get msaAreaHeight(){return e.height-(e.showHorizontalScrollbar?e.minimapHeight:0)-e.headerHeight},get totalTrackAreaHeight(){return(0,Ze.sum)(e.turnedOnTracks.map(t=>t.model.height))},get tidyInterProAnnotationTypes(){return new Map(this.tidyInterProAnnotations.map(t=>[t.accession,t]))},get tidyInterProAnnotations(){return e.interProAnnotations?Object.entries(e.interProAnnotations).flatMap(([t,r])=>r.matches.flatMap(({signature:n,locations:o})=>{let{entry:i}=n;return i?o.map(({start:a,end:s,strand:c})=>({id:t,name:i.name,accession:i.accession,description:i.description,featureType:i.featureType,start:a,end:s,strand:c})):[]})).toSorted((t,r)=>fp(r)-fp(t)):[]},get tidyFilteredInterProAnnotations(){return this.tidyInterProAnnotations.filter(t=>e.featureFilters.get(t.accession))},get tidyFilteredGatheredInterProAnnotations(){return(0,Ze.groupBy)(this.tidyFilteredInterProAnnotations,t=>t.id)}})).views(e=>({get showVerticalScrollbar(){return e.msaAreaHeight<e.totalHeight}})).views(e=>({get verticalScrollbarWidth(){return e.showVerticalScrollbar?20:0},get segmentDomainTypes(){return[...e.tidyInterProAnnotationTypes.values()].filter(t=>Xm.has(t.featureType??"")).toSorted((t,r)=>t.start-r.start)},get categoricalDomainTypes(){return[...e.tidyInterProAnnotationTypes.values()].filter(t=>!Xm.has(t.featureType??""))},get fillPalette(){let t=Object.fromEntries(this.segmentDomainTypes.map((n,o)=>[n.accession,Zm[o%Zm.length]])),r=Dk(this.categoricalDomainTypes.map(n=>n.accession));return{...t,...r}},get strokePalette(){return ba(this.fillPalette,([t,r])=>[t,rt(r).darken(.1).toHex()])},get segmentLabels(){return new Map(this.segmentDomainTypes.map((t,r)=>{let n=/(\d+)\s*$/.exec(t.name);return[t.accession,n?n[1]:`${r+1}`]}))},get visibleDomainTypes(){return this.categoricalDomainTypes.filter(t=>e.featureFilters.get(t.accession)).toSorted((t,r)=>t.start-r.start)},get domainBands(){let t=new Map;for(let[r,n]of Object.entries(e.tidyFilteredGatheredInterProAnnotations)){let o=n.map((i,a)=>{let s=e.seqPosToVisibleCol(r,i.start-1),c=e.seqPosToVisibleCol(r,i.end-1);return s!==void 0&&c!==void 0?{annotation:i,startCol:s,endCol:c+1,stackIndex:a}:void 0}).filter(Ze.notEmpty);o.length>0&&t.set(r,o)}return t},get domainBandsByStart(){return new Map([...this.domainBands].map(([t,r])=>[t,r.toSorted((n,o)=>n.startCol-o.startCol)]))},get mouseOverDomains(){let{mouseCol:t}=e,r=e.mouseOverRowName;return r!==void 0&&t!==void 0?(this.domainBands.get(r)??[]).filter(n=>t>=n.startCol&&t<n.endCol).map(n=>n.annotation):[]},get referenceRowIndex(){let{relativeTo:t}=e;return t===void 0?void 0:e.rowNamesSet.get(t)},get hoveredRowIndices(){let{hoveredTreeNode:t,rowNamesSet:r}=e;return t?t.descendantNames.map(n=>r.get(n)).filter(Ze.notEmpty):[]},get highlightedColumnRuns(){let{highlightedColumns:t}=e,r=[];for(let n of[...t??[]].sort((o,i)=>o-i)){let o=r.at(-1);o&&n===o.end+1?o.end=n:r.push({start:n,end:n})}return r},get mouseOverColumnStats(){let{mouseCol:t}=e;if(t===void 0)return;let{colStats:r}=e,n=r.total(t);if(t>=r.numColumns||!n)return;let o=r.gapCount(t),i=r.residueEntries(t).sort((s,c)=>c[1]-s[1]),a=i[0];return{col:t,total:n,gaps:o,gapFraction:o/n,conservation:e.conservation[t]??0,propertyConservation:e.propertyConservation[t],consensusLetter:a?.[0]??"",consensusCount:a?.[1]??0,consensusFraction:a?a[1]/n:0,distribution:i}},getRowData(t){return{data:e.MSA?.getRowData(t),treeMetadata:e.treeMetadata[t]}}})).actions(e=>({setHeaderHeight(t){e.headerHeight=t},setConservationTrackHeight(t){e.conservationTrackHeight=t},reset(){e.setData({tree:"",msa:""}),e.resetZoom(),e.setError(void 0),e.setScrollY(0),e.setScrollX(0),e.setCurrentAlignment(0),e.setTreeFilehandle(void 0),e.setMSAFilehandle(void 0),e.setGFFFilehandle(void 0),e.setDomains(void 0)},async exportSVG(t){let{renderToSvg:r}=await Promise.resolve().then(()=>(wp(),RI)),n=await r(e,t),o=new Blob([n],{type:"image/svg+xml"});lD(o,"image.svg")},initFilter(t){e.featureFilters.has(t)||e.featureFilters.set(t,!0)},setFilter(t,r){e.featureFilters.set(t,r)},fit(){this.fitVertically(),this.fitHorizontally()},fitVertically(){e.numRows>0&&(e.rowHeight=(0,Ze.clamp)(e.msaAreaHeight/e.numRows,Iu,Zo)),e.scrollY=0},fitHorizontally(){e.numColumns>0&&(e.colWidth=(0,Ze.clamp)(e.msaAreaWidth/e.numColumns,bu,Zo)),e.scrollX=0},afterCreate(){if(e.highlightColumns?.length&&e.setHighlightedColumns(e.highlightColumns),(0,K.addDisposer)(e,(0,St.autorun)(()=>{for(let n of e.tidyInterProAnnotationTypes.keys())this.initFilter(n)})),typeof window<"u"&&typeof window.matchMedia=="function"){let n=()=>window.matchMedia(`(resolution: ${window.devicePixelRatio}dppx)`),o=n(),i=()=>{e.setHighResScaleFactor(window.devicePixelRatio),o.removeEventListener("change",i),o=n(),o.addEventListener("change",i)};o.addEventListener("change",i),(0,K.addDisposer)(e,()=>{o.removeEventListener("change",i)})}let t=0;(0,K.addDisposer)(e,(0,St.autorun)(async()=>{let{treeFilehandle:n}=e;if(n){let o=++t;try{e.setLoadingTree(!0);let i=await kc((0,Jc.openLocation)(n),a=>{o===t&&e.setStatus(a)});o===t&&(0,St.transaction)(()=>{e.setTree(i),n.locationType==="BlobLocation"&&e.setTreeFilehandle(void 0)})}catch(i){o===t&&(yo(i)?e.setTreeFilehandle(void 0):(console.error(i),e.setError(i)))}finally{o===t&&e.setLoadingTree(!1)}}})),(0,K.addDisposer)(e,(0,St.autorun)(async()=>{let{treeMetadataFilehandle:n}=e;if(n)try{e.setTreeMetadata(await kc((0,Jc.openLocation)(n),o=>{e.setStatus(o)}))}catch(o){yo(o)||(console.error(o),e.setError(o))}})),(0,K.addDisposer)(e,(0,St.autorun)(()=>{let n=e.data.gff;if(n)try{e.applyGFFText(n)}catch(o){console.error(o),e.setError(o)}})),(0,K.addDisposer)(e,(0,St.autorun)(async()=>{let{gffFilehandle:n}=e;if(n)try{let o=await kc((0,Jc.openLocation)(n),i=>{e.setStatus(i)});e.applyGFFText(o),n.locationType==="BlobLocation"&&e.setGFFFilehandle(void 0)}catch(o){yo(o)?e.setGFFFilehandle(void 0):(console.error(o),e.setError(o))}}));let r=0;(0,K.addDisposer)(e,(0,St.autorun)(async()=>{let{msaFilehandle:n}=e;if(n){let o=++r;try{e.setLoadingMSA(!0),e.setError(void 0);let i=await kc((0,Jc.openLocation)(n),a=>{o===r&&e.setStatus(a)});o===r&&(0,St.transaction)(()=>{e.setMSA(i),n.locationType==="BlobLocation"&&e.setMSAFilehandle(void 0)})}catch(i){o===r&&(yo(i)?e.setMSAFilehandle(void 0):(console.error(i),e.setError(i)))}finally{o===r&&e.setLoadingMSA(!1)}}})),(0,K.addDisposer)(e,(0,St.autorun)(()=>{e.colorSchemeName.includes("dynamic")&&e.colStats,e.showColumnStats&&(e.colStats,e.conservation,e.propertyConservation),e.columns})),(0,K.addDisposer)(e,(0,St.autorun)(()=>{e.autoTreeAreaWidth&&(e.noTree||!e.drawTree)&&e.labelsWidth&&e.setTreeAreaWidth(e.labelsWidth+e.marginLeft+12)})),(0,K.addDisposer)(e,(0,St.autorun)(()=>{e.setTreeWidth(Math.max(50,e.treeAreaWidth-e.labelsWidth-10-e.marginLeft))}))}})).postProcessSnapshot(({data:e,...t})=>({...t,data:{...t.treeFilehandle?{}:{tree:e.tree},...t.msaFilehandle?{}:{msa:e.msa},...t.treeMetadataFilehandle?{}:{treeMetadata:e.treeMetadata}}}))}var Ze,Jc,wi,K,St,gA,w0=d(()=>{Ze=p(Be(),1),Jc=p(f0(),1),wi=p(gk(),1),K=p(Vt(),1);rc();St=p(Ca(),1);Nh();hk();Ik();gh();m0();Qk();_k();Zs();Nk();kf();Lk();hp();Pk();Gk();Vk();Yk();qk();Kk();Zk();nD();aD();cD();mA();so();uD();gA=I9});var S0,dD,w9,pue,mD=d(()=>{S0=p(k(),1),dD=p(dk(),1),w9=p(Qp(),1);w0();u0();pue=(0,dD.createJBrowseTheme)()});var B0=d(()=>{wp();u0();mD();w0()});var mN=z((Lfe,dN)=>{dN.exports=JBrowseExports["@jbrowse/core/data_adapters/BaseAdapter"]});var hN={};bt(hN,{default:()=>kA});var pN,gN,kA,CN=d(()=>{"use strict";pN=p(Hi()),gN=p(mN());rv();kA=class extends gN.BaseAdapter{async configurePre(){let t=this.getSubAdapter;if(t)return(await t({...(0,pN.readConfObject)(this.config),type:"BgzipFastaAdapter"})).dataAdapter;throw new Error("no get subadapter")}configure(){return this.configureP??=this.configurePre().catch(t=>{throw this.configureP=void 0,t}),this.configureP}async getMSARefs(){return this.refNamesP??=this.configure().then(t=>t.getRefNames()).catch(t=>{throw this.refNamesP=void 0,t}),this.refNamesP}getMsaRegex(){return new RegExp(this.getConf("msaRegex"))}refNameToMsaId(t){return t.split(this.getMsaRegex())[0]}async getMSAList(){let t=await this.getMSARefs();return[...new Set(t.map(n=>this.refNameToMsaId(n)))]}async getMSA(t){let r=await this.configure(),o=(await this.getMSARefs()).filter(i=>this.refNameToMsaId(i)===t);return jg(r.getFeaturesInMultipleRegions(o.map(i=>({refName:i,start:0,end:1e9,assemblyName:""}))).pipe(Yg()))}}});var FN=z(LN=>{"use strict";var us=k();function hH(e,t){return e===t&&(e!==0||1/e===1/t)||e!==e&&t!==t}var CH=typeof Object.is=="function"?Object.is:hH,yH=us.useState,xH=us.useEffect,EH=us.useLayoutEffect,bH=us.useDebugValue;function IH(e,t){var r=t(),n=yH({inst:{value:r,getSnapshot:t}}),o=n[0].inst,i=n[1];return EH(function(){o.value=r,o.getSnapshot=t,j0(o)&&i({inst:o})},[e,r,t]),xH(function(){return j0(o)&&i({inst:o}),e(function(){j0(o)&&i({inst:o})})},[e]),bH(r),r}function j0(e){var t=e.getSnapshot;e=e.value;try{var r=t();return!CH(e,r)}catch{return!0}}function wH(e,t){return t()}var SH=typeof window>"u"||typeof window.document>"u"||typeof window.document.createElement>"u"?wH:IH;LN.useSyncExternalStore=us.useSyncExternalStore!==void 0?us.useSyncExternalStore:SH});var ON=z((oAe,PN)=>{"use strict";PN.exports=FN()});var BR,vR,TR=d(()=>{"use client";Ee();BR=p(O(),1),vR=Y((0,BR.jsx)("path",{d:"M19 19H5V5h7V3H5c-1.11 0-2 .9-2 2v14c0 1.1.89 2 2 2h14c1.1 0 2-.9 2-2v-7h-2zM14 3v2h3.59l-9.83 9.83 1.41 1.41L19 6.41V10h2V3z"}),"OpenInNew")});function Qi(e){let{children:t,...r}=e;return lC.default.createElement(QR.Link,{...r,target:"_blank",rel:"noreferrer"},t," ",lC.default.createElement(vR,{fontSize:"small"}))}var lC,QR,XA=d(()=>{"use strict";lC=p(k());TR();QR=p(V())});var oL=z((Tme,nL)=>{nL.exports=JBrowseExports["@jbrowse/core/pluggableElementTypes/ViewType"]});var il,iL,nd,aL=d(()=>{"use strict";il=p(k()),iL=p(Ye()),nd=class extends il.Component{constructor(t){super(t),this.state={hasError:!1,error:null}}static getDerivedStateFromError(t){return{hasError:!0,error:t}}componentDidCatch(t,r){console.error("MsaViewPanel error:",t,r.componentStack)}render(){return this.state.hasError?il.default.createElement("div",{style:{padding:20}},il.default.createElement(iL.ErrorMessage,{error:this.state.error})):this.props.children}}});function AV({baseUrl:e,rid:t}){return CC.default.createElement(sL.Typography,null,"RID ",t," (",CC.default.createElement(Qi,{href:`${e}?CMD=Get&RID=${t}`},"see status"),")")}var CC,sL,yC,cL=d(()=>{"use strict";CC=p(k()),sL=p(V());XA();yC=AV});function dV({baseUrl:e,rid:t,error:r}){return Qr.default.createElement("div",null,t?Qr.default.createElement(yC,{rid:t,baseUrl:e}):null,Qr.default.createElement(od.ErrorMessage,{error:r}))}function mV({baseUrl:e,rid:t,progress:r}){let{classes:n}=fL();return Qr.default.createElement("div",{className:n.loading},t?Qr.default.createElement(yC,{baseUrl:e,rid:t}):null,Qr.default.createElement(xC.Typography,null,r))}var Qr,od,xC,lL,uL,fL,pV,AL,dL=d(()=>{"use strict";Qr=p(k()),od=p(Ye()),xC=p(V()),lL=p($()),uL=p(Rt());cL();fL=(0,uL.makeStyles)()(e=>({margin:{padding:20},loading:{background:e.palette.background.paper}}));pV=(0,lL.observer)(function({model:t,baseUrl:r}){let{progress:n,rid:o,error:i}=t,{classes:a}=fL();return Qr.default.createElement("div",{className:a.margin},Qr.default.createElement(od.LoadingEllipses,{message:"Running NCBI BLAST",variant:"h5"}),i?Qr.default.createElement(dV,{baseUrl:r,rid:o,error:i}):o?Qr.default.createElement(mV,{baseUrl:r,rid:o,progress:n}):Qr.default.createElement(xC.Typography,null,n||"Initializing BLAST query"))}),AL=pV});var hL={};bt(hL,{default:()=>CV});var Mi,mL,pL,gL,gV,hV,CV,CL=d(()=>{"use strict";Mi=p(k()),mL=p(Ye()),pL=p($());B0();gL=p(Rt());aL();dL();gV=(0,gL.makeStyles)()({loadingContainer:{padding:20}}),hV=(0,pL.observer)(function({model:t}){let{classes:r}=gV(),{blastParams:n,loadingStoredData:o}=t;return Mi.default.createElement(nd,null,Mi.default.createElement("div",null,n?Mi.default.createElement(AL,{model:t,baseUrl:n.baseUrl}):o?Mi.default.createElement("div",{className:r.loadingContainer},Mi.default.createElement(mL.LoadingEllipses,{message:"Loading MSA data",variant:"h6"})):Mi.default.createElement(uA,{model:t})))}),CV=hV});var xV={};bt(xV,{default:()=>id});var bL=p(HC()),bC=p(Hi()),IL=p(Be()),IC=p(Vt());Ee();var Mb=p(O(),1),_b=Y((0,Mb.jsx)("path",{d:"M20 2H4c-1.1 0-2 .9-2 2v16c0 1.1.9 2 2 2h16c1.1 0 2-.9 2-2V4c0-1.1-.9-2-2-2M8 20H4v-4h4zm0-6H4v-4h4zm0-6H4V4h4zm6 12h-4v-4h4zm0-6h-4v-4h4zm0-6h-4V4h4zm6 12h-4v-4h4zm0-6h-4v-4h4zm0-6h-4V4h4z"}),"GridOn");var uN=p(k()),fN=p(Be());var Xc=p(k()),cN=p($());var N0=p(k()),oN=p(Be()),R0=p($());var Rb=p(Rt());function Ko(e){return!!e&&typeof e=="object"&&"hoverPosition"in e&&!!e.hoverPosition}function Nb(e){return/AF-([A-Z0-9]+)-F\d+/.exec(e)?.[1]}var xu=(0,Rb.makeStyles)()({highlight:{height:"100%",background:"rgba(255,255,0,0.2)",border:"1px solid rgba(50,50,0,0.2)",position:"absolute",zIndex:99,textAlign:"center",pointerEvents:"none",overflow:"hidden"}});var rN=p(zm()),nN=p(Be()),gt=p(Vt());function Fb(e){let t=e.strand,r=e.refName;if(t!==-1&&t!==1)throw new Error(`Invalid strand value: ${t}. Expected 1 or -1.`);if(!r)throw new Error("refName is required");let n=new Map;for(let c of e.subfeatures??[])if(c.type==="CDS"&&c.start<c.end){let l=`${c.start}-${c.end}`;n.has(l)||n.set(l,c)}let o=[...n.values()].sort((c,l)=>t*(c.start-l.start)),i={},a={},s={};if(o.length!==0){let l=(3-(o[0]?.phase??0))%3,u=-1;for(let A of o){let m=A.end-A.start;for(let f=0;f<m;f++){let g=t===1?A.start+f:A.end-1-f,y=Math.floor(l++/3);i[g]=y,y!==u?(a[y]=g,s[y]=[g],u=y):s[y].push(g)}}}return{g2p:i,p2g:a,p2gCodon:s,refName:r,strand:t}}var _A=p(Ca());B0();var qD=p(Be());function pD(e,t){let r=e.sciname.replaceAll(" ","_");if(e.taxid&&t?.has(e.taxid)){let n=t.get(e.taxid);n.commonName&&(r=n.commonName.split(" ").map(o=>o.charAt(0).toUpperCase()+o.slice(1).toLowerCase()).join("_"))}return`${e.accession}-${r}`}function gD(e){return e.replaceAll("-","")}var CA=p(Be());function Sr(e){return(0,CA.getContainingView)(e)}function hD(e){return[...new Set(e.filter(t=>!!t))]}function CD(e,t){return t.filter(r=>!!r).join(e)}function S9(e){let r=(e.get("subfeatures")??[]).filter(n=>(n.get("type")==="mRNA"||n.get("type")==="transcript")&&n.get("subfeatures")?.some(o=>o.get("type")==="CDS"));return r.length>0?r:[e]}function hA(e){let t=(0,CA.sum)(e.get("subfeatures")?.filter(r=>r.get("type")==="CDS").map(r=>r.get("end")-r.get("start"))??[]);return{len:Math.floor(t/3),mod:t%3}}function Si(e){return e?.id()??""}function B9(e){return e?hD([e.id(),e.get("name"),e.get("id"),e.get("transcript_id")]):[]}function ss(e,t){return B9(e).includes(t)}function yA(e){return e?CD(" ",[e.get("name"),e.get("id")]):""}function Bi(e){return e?CD(" ",[e.get("gene_name")??e.get("name"),e.get("id")?`(${e.get("id")})`:void 0]):""}function xA(e,t){return`BLAST - ${Bi(e)} - ${yA(t)}`}function EA(e){return S9(e).toSorted((r,n)=>hA(n).len-hA(r).len)}function bA(e){return e.replaceAll("*","").replaceAll("&","")}function IA(e){return hD([e.id(),e.get("id"),e.get("name"),e.get("gene_id"),e.get("gene_name")])}ja();var v9="jbrowse-msaview-blast-cache",ko="blast-results",T9=2,v0;function wA(){return v0??=Vn(v9,T9,{upgrade(e,t){t<2&&e.objectStoreNames.contains(ko)&&e.deleteObjectStore(ko),e.objectStoreNames.contains(ko)||e.createObjectStore(ko,{keyPath:"id"})}}).catch(e=>{throw v0=void 0,e}),v0}function Q9(e,t,r,n,o){let i=o?`:${o}`:"";return`${t}:${r}:${n}${i}:${e}`}async function yD({proteinSequence:e,blastDatabase:t,blastProgram:r,msaAlgorithm:n,msa:o,tree:i,treeMetadata:a,rid:s,geneId:c,transcriptId:l,transcriptName:u,geneName:A}){let m=await wA(),g={id:Q9(e,t,r,n,l),proteinSequence:e,blastDatabase:t,blastProgram:r,msaAlgorithm:n,msa:o,tree:i,treeMetadata:a,rid:s,timestamp:Date.now(),geneId:c,transcriptId:l,transcriptName:u,geneName:A};return await m.put(ko,g),g}async function xD(){return(await(await wA()).getAll(ko)).toSorted((r,n)=>n.timestamp-r.timestamp)}async function ED(e){await(await wA()).delete(ko,e)}async function bD(){await(await wA()).clear(ko)}async function ID(e,t){let r=await fetch(e,t);if(!r.ok)throw new Error(`HTTP ${r.status} fetching ${e} ${await r.text()}`);return r}async function wn(e,t){return(await ID(e,t)).text()}async function wD(e,t){return(await ID(e,t)).json()}function SD(e){return new Promise(t=>setTimeout(t,e))}async function SA({check:e,intervalSeconds:t,onCountdown:r}){for(;;){if(await e())return;for(let n=t;n>0;n--)r(n),await SD(1e3)}}var vA="https://www.ebi.ac.uk/Tools/services/rest",BA="colin.diesh@gmail.com",M9={clustalo:{params:{email:BA},msaResult:"aln-clustal_num",treeResult:"phylotree"},muscle:{params:{email:BA,format:"clw",tree:"tree1"},msaResult:"fa",treeResult:"phylotree"},kalign:{params:{email:BA,stype:"protein"},msaResult:"fa",treeResult:"phylotree"},mafft:{params:{email:BA,stype:"protein"},msaResult:"fa",treeResult:"phylotree"}};async function _9({onProgress:e,jobId:t,algorithm:r}){await SA({intervalSeconds:10,onCountdown:n=>{e(`Re-checking MSA status in... ${n}`)},check:async()=>{let n=await wn(`${vA}/${r}/status/${t}`);if(n.includes("FINISHED"))return!0;if(n.includes("FAILURE"))throw new Error(`Failed to run: jobId ${t}`);return!1}})}async function BD({algorithm:e,sequence:t,onProgress:r}){let n=M9[e];r(`Launching ${e} MSA...`);let o=await wn(`${vA}/${e}/run`,{method:"POST",body:new URLSearchParams({...n.params,sequence:t})});return await _9({jobId:o,algorithm:e,onProgress:r}),{msa:await wn(`${vA}/${e}/result/${o}/${n.msaResult}`),tree:await wn(`${vA}/${e}/result/${o}/${n.treeResult}`)}}async function T0({rid:e,baseUrl:t,onProgress:r}){r(`Checking BLAST status for RID: ${e}...`),await D9({rid:e,onProgress:r,baseUrl:t});let n=await wD(`${t}?CMD=Get&RID=${e}&FORMAT_TYPE=JSON2_S&FORMAT_OBJECT=Alignment`);return{rid:e,hits:n.BlastOutput2[0]?.report.results.search.hits??[]}}async function vD({query:e,blastDatabase:t,blastProgram:r,baseUrl:n,onProgress:o,onRid:i}){o("Submitting to NCBI BLAST...");let{rid:a}=await k9({query:e,blastDatabase:t,blastProgram:r,baseUrl:n});return i(a),T0({rid:a,baseUrl:n,onProgress:o})}async function k9({query:e,blastProgram:t,blastDatabase:r,baseUrl:n}){let o=await wn(n,{method:"POST",body:new URLSearchParams({CMD:"Put",PROGRAM:t==="quick-blastp"?"blastp":t,DATABASE:r,QUERY:e,...r==="nr_cluster_seq"?{CLUSTERED_DB:"on",DB_TYPE:"Experimental Databases"}:{},...t==="quick-blastp"?{BLAST_PROGRAMS:"kmerBlastp"}:{}})}),i=/^ {4}RID = (.*$)/m.exec(o)?.[1],a=/^ {4}RTOE = (.*$)/m.exec(o)?.[1];if(!i)throw new Error("Failed to get RID from BLAST request");return{rid:i,rtoe:a}}async function D9({rid:e,onProgress:t,baseUrl:r}){await SA({intervalSeconds:20,onCountdown:n=>{t(`Re-checking BLAST status in... ${n}`)},check:async()=>{let n=await wn(`${r}?CMD=Get&FORMAT_OBJECT=SearchInfo&RID=${e}`),o=/\s+Status=(\S+)/m.exec(n)?.[1],i=/\s+ThereAreHits=yes/m.test(n);if(o==="WAITING")return!1;if(o==="FAILED")throw new Error(`BLAST ${e} failed`);if(o==="READY"){if(i)return!0;throw new Error("No hits found")}throw new Error(`BLAST ${e} returned unexpected status: ${o??"unknown"}`)}})}ja();var N9="jbrowse-plugin-msaview",R9="colin.diesh@gmail.com",L9="https://eutils.ncbi.nlm.nih.gov/entrez/eutils";function TA(e){let t=new URLSearchParams({...e,tool:N9,email:R9});return`${L9}/efetch.fcgi?${t.toString()}`}var F9="jbrowse-msaview-taxonomy-cache",Wc="common-names",P9=2,Q0;function TD(){return Q0??=Vn(F9,P9,{upgrade(e){e.objectStoreNames.contains(Wc)&&e.deleteObjectStore(Wc),e.createObjectStore(Wc,{keyPath:"taxid"})}}).catch(e=>{throw Q0=void 0,e}),Q0}async function O9(e){let r=(await TD()).transaction(Wc,"readonly"),n=await Promise.all(e.map(o=>r.store.get(o)));return await r.done,n}async function G9(e){let r=(await TD()).transaction(Wc,"readwrite");for(let n of e)await r.store.put(n);await r.done}async function QD(e){let t=new Map,r=[],n=await O9(e);for(let a=0;a<e.length;a++){let s=e[a],c=n[a];c?t.set(s,{sciname:c.sciname,commonName:c.commonName}):r.push(s)}if(r.length===0)return t;let o=100,i=[];for(let a=0;a<r.length;a+=o){let s=r.slice(a,a+o),c=s.join(",");try{let u=await(await fetch(TA({db:"taxonomy",id:c,retmode:"xml"}))).text(),A=new Map,m=/<Taxon>\s*<TaxId>(\d+)<\/TaxId>/g,f;for(;(f=m.exec(u))!==null;){let g=Number(f[1]),y=f.index,E=1,b=y+f[0].length;for(;E>0&&b<u.length;){let S=u.indexOf("<Taxon>",b),v=u.indexOf("</Taxon>",b);if(v===-1)break;S!==-1&&S<v?(E++,b=S+7):(E--,b=v+8)}let x=u.slice(y,b),B=A.get(g),I=x.includes("<LineageEx>"),w=B?.includes("<LineageEx>");(!B||I&&!w)&&A.set(g,x)}for(let g of s){let y=A.get(g);if(y){let E=/<GenbankCommonName>(.*?)<\/GenbankCommonName>/.exec(y),b=/<CommonName>(.*?)<\/CommonName>/.exec(y),x=/<ScientificName>(.*?)<\/ScientificName>/.exec(y),B=E?.[1]??b?.[1],I=x?.[1]??"";t.set(g,{sciname:I,commonName:B}),i.push({taxid:g,sciname:I,commonName:B})}}}catch(l){console.error("Failed to fetch taxonomy data:",l)}}return i.length>0&&await G9(i),t}async function MD({self:e}){let{baseUrl:t,blastDatabase:r,blastProgram:n,msaAlgorithm:o,proteinSequence:i,selectedTranscript:a,rid:s}=e.blastParams,c=bA(i),l,u;if(s){e.setRid(s);let b=await T0({rid:s,baseUrl:t,onProgress:x=>{e.setProgress(x)}});l=b.hits,u=b.rid}else{let b=await vD({query:c,blastDatabase:r,blastProgram:n,baseUrl:t,onProgress:x=>{e.setProgress(x)},onRid:x=>{e.setRid(x)}});l=b.hits,u=b.rid}e.setProgress("Fetching species taxonomy info...");let A=l.map(b=>b.description[0]?.taxid).filter(b=>b!==void 0),m=await QD(A),f={},g=l.map(b=>{let x=b.description[0]??{accession:"unknown",id:"unknown",sciname:"unknown"},B=pD(x,m),I=gD(b.hsps[0]?.hseq??"");return f[B]=U9(x,m),`>${B}
+${I}`}),y=await BD({algorithm:o,sequence:[`>QUERY
 ${c}`,...g].join(`
-`),onProgress:I=>{e.setProgress(I)}}),y=JSON.stringify(d);return await ZQ({proteinSequence:c,blastDatabase:r,blastProgram:n,msaAlgorithm:o,msa:C.msa,tree:C.tree,treeMetadata:y,rid:A,geneId:a?.get("parentId"),transcriptId:a?.id(),transcriptName:a?.get("name")??a?.get("id"),geneName:a?.get("gene_name")??a?.get("parentId")}),{...C,treeMetadata:y}}function x5(e,t){let r={},n=e.taxid?t.get(e.taxid):void 0;return n?.sciname&&(r["Scientific name"]=n.sciname),n?.commonName&&(r["Common name"]=n.commonName),e.accession&&(r.Accession=e.accession),e.id&&(r.ID=e.id),e.title&&(r.Description=e.title),r}Vf();var fv=f(Pm());async function dv({location:e,name:t}){let r=i=>(0,fv.openLocation)({uri:i,locationType:"UriLocation"}),n=await r(`${e.uri}.idx`).readFile("utf8"),o=y5(n,t);if(o){let a=await new Bi({filehandle:r(e.uri),gziFilehandle:r(`${e.uri}.gzi`)}).read(o.length,o.offset);return new TextDecoder().decode(a).trim()}}var uv=e=>e.replace(/\.\d+$/,"");function y5(e,t){let r=uv(t);for(let n of e.split(`
-`)){let[o,i,a]=n.split("	");if(o&&uv(o)===r)return{offset:Number(i),length:Number(a)}}}var mv=f(de());function pv({model:e}){let{hovered:t}=(0,mv.getSession)(e),{querySeqName:r,transcriptToMsaMap:n,connectedView:o,mafRegion:i}=e;if(!o?.initialized||!Zn(t))return;let{coord:a,refName:s}=t.hoverPosition;if(i)return s!==i.refName||!o.assemblyNames.includes(i.assemblyName)||a<i.start||a>=i.end?void 0:e.seqPosToVisibleCol(r,a-i.start);if(n){let c=n.g2p[a];if(c!==void 0)return e.seqPosToVisibleCol(r,c)}}_i();var w5="jbrowse-msaview-domain-cache",oA="domains",b5=1,ep;function gv(){return ep??=cn(w5,b5,{upgrade(e){e.objectStoreNames.contains(oA)||e.createObjectStore(oA,{keyPath:"accession"})}}).catch(e=>{throw ep=void 0,e}),ep}async function hv(e){let r=(await gv()).transaction(oA,"readonly"),n=await Promise.all(e.map(o=>r.store.get(o)));return await r.done,n}async function Cv(e){let r=(await gv()).transaction(oA,"readwrite");for(let n of e)await r.store.put(n);await r.done}function Yn(e,t){return new RegExp(`<${t}>(.*?)</${t}>`,"s").exec(e)?.[1]}function B5(e){let t={},r=/<GBQualifier>([\s\S]*?)<\/GBQualifier>/g,n;for(;(n=r.exec(e))!==null;){let o=Yn(n[1],"GBQualifier_name"),i=Yn(n[1],"GBQualifier_value");o&&i!==void 0&&t[o]===void 0&&(t[o]=i)}return t}function S5(e){let t=[],r=[],n=/<GBInterval>([\s\S]*?)<\/GBInterval>/g,o;for(;(o=n.exec(e))!==null;){let i=o[1],a=Yn(i,"GBInterval_from"),s=Yn(i,"GBInterval_to"),c=Yn(i,"GBInterval_point");a&&s?(t.push(Number(a)),r.push(Number(s))):c&&(t.push(Number(c)),r.push(Number(c)))}return t.length>0?{start:Math.min(...t),end:Math.max(...r)}:void 0}var Q5=2;function v5(e){let t=Yn(e,"GBFeature_key"),r=B5(e),n=r.db_xref,o=S5(e);if((t==="Region"||t==="Site")&&n?.startsWith("CDD:")&&o&&o.end-o.start+1>=Q5){let i=n.replace("CDD:",""),a=t==="Region",s=r.note?.split(/[[(]/)[0]?.trim(),c=a?r.region_name??i:s||r.site_type||"site",l=a?i:`${i}:${c}`;return{signature:{entry:{name:c,description:r.note??c,accession:l}},locations:[o]}}}function M5(e){let t=new Map,r=/<GBSeq>([\s\S]*?)<\/GBSeq>/g,n;for(;(n=r.exec(e))!==null;){let o=n[1],i=[],a=/<GBFeature>([\s\S]*?)<\/GBFeature>/g,s;for(;(s=a.exec(o))!==null;){let c=v5(s[1]);c&&i.push(c)}for(let c of[Yn(o,"GBSeq_accession-version"),Yn(o,"GBSeq_primary-accession")])c&&t.set(c,i)}return t}async function Ev(e){let t=[...new Set(e)].filter(Boolean),r=new Map,n=await hv(t),o=[];t.forEach((s,c)=>{let l=n[c];l?r.set(s,l.matches):o.push(s)});let i=[],a=100;for(let s=0;s<o.length;s+=a){let c=o.slice(s,s+a),l=await Yr(nA({db:"protein",id:c.join(","),rettype:"gp",retmode:"xml"})),A=M5(l);for(let u of c){let m=A.get(u);m!==void 0&&(r.set(u,m),i.push({accession:u,matches:m}))}}return i.length>0&&await Cv(i),r}async function Iv(e){let t=e.data.treeMetadata;if(!t)throw new Error("No sequence metadata available to look up domains");let r=JSON.parse(t),n=Object.entries(r).map(([a,s])=>({rowName:a,accession:s.Accession})).filter(a=>!!a.accession);if(n.length===0)throw new Error("No NCBI accessions found in alignment rows");e.setProgress(`Fetching protein domains from NCBI for ${n.length} sequences...`);let o=await Ev(n.map(a=>a.accession)),i={};for(let{rowName:a,accession:s}of n){let c=o.get(s);c&&c.length>0&&(i[a]={matches:c,xref:[{id:a}]})}if(Object.keys(i).length===0)throw new Error("No CDD domain annotations found for these proteins");e.setDomains(i)}_i();var _5="jbrowse-msaview-data",T5=1,ds="msa-data",tp;function rp(){return tp??=cn(_5,T5,{upgrade(e){e.objectStoreNames.contains(ds)||e.createObjectStore(ds,{keyPath:"id"}).createIndex("timestamp","timestamp",{unique:!1})}}).catch(e=>{throw tp=void 0,e}),tp}function xv(){return`msa-${Date.now()}-${Math.random().toString(36).slice(2,11)}`}async function yv(e,t){try{let r=await rp(),n={id:e,msa:t.msa,tree:t.tree,treeMetadata:t.treeMetadata,timestamp:Date.now()};return await r.put(ds,n),!0}catch(r){return console.warn("Failed to store MSA data:",r),!1}}async function wv(e){try{let r=await(await rp()).get(ds,e);return r?{msa:r.msa,tree:r.tree,treeMetadata:r.treeMetadata}:void 0}catch(t){console.warn("Failed to retrieve MSA data:",t);return}}async function bv(e=10080*60*1e3){try{let t=await rp(),r=Date.now()-e,i=await t.transaction(ds,"readwrite").store.index("timestamp").openCursor(IDBKeyRange.upperBound(r)),a=0;for(;i;)await i.delete(),a++,i=await i.continue();return a}catch(t){return console.warn("Failed to cleanup old MSA data:",t),0}}function k5(e){let t=e;return t.type==="ProteinView"&&Array.isArray(t.structures)}function Bv(e){return e.filter(k5)}function Sv(e,t){if(t<0||t>=e.length)return;let r=0;for(let n=0;n<t;n++)e[n]!=="-"&&r++;if(e[t]!=="-")return r}function vv(e){let{dataStoreId:t,rows:r}=e;t&&r.length===0&&(async()=>{try{e.setLoadingStoredData(!0);let n=await wv(t);n&&(n.msa&&e.setMSA(n.msa),n.tree&&e.setTree(n.tree),n.treeMetadata&&e.setTreeMetadata(n.treeMetadata))}catch(n){console.error("Failed to load MSA data from IndexedDB:",n)}finally{e.setLoadingStoredData(!1)}})()}function Mv(e){let{rows:t,dataStoreId:r,isStoringData:n}=e;if(t.length>0&&!r&&!n){if(e.msaFilehandle||e.treeFilehandle)return;let o=e.data.msa,i=e.data.tree;(o||i)&&(e.setIsStoringData(!0),(async()=>{try{let a=xv();await yv(a,{msa:o,tree:i,treeMetadata:e.data.treeMetadata})&&e.setDataStoreId(a)}catch(a){console.error("Failed to store MSA data to IndexedDB:",a)}finally{e.setIsStoringData(!1)}})())}}function _v(e){e.blastParams&&(async()=>{try{e.setProgress("Submitting query"),e.setError(void 0);let t=await Av({self:e});e.setData(t),e.setBlastParams(void 0)}catch(t){e.setError(t),console.error(t)}finally{e.setProgress("")}})()}function Tv(e){let{rows:t,domainsRequested:r,interProAnnotations:n}=e,o=e.data.treeMetadata?.includes('"Accession"')??!1;t.length>0&&o&&!n&&!r&&(e.setDomainsRequested(!0),(async()=>{try{await Iv(e)}catch(i){console.error("[msaview-domains] auto-load failed:",i)}finally{e.setProgress("")}})())}function kv(e){let{init:t}=e;if(t){let{msaUrl:r,msaIndexedLocation:n,msaName:o,querySeqName:i}=t;(async()=>{try{if(e.setError(void 0),r){let a=wg(r);a&&(e.setUniprotId(a),e.setQuerySeqName("query"))}if(i&&e.setQuerySeqName(i),r)e.setMSAFilehandle({uri:r,locationType:"UriLocation"});else if(n&&o){let a=await dv({location:n,name:o});if(a)e.setMSA(a);else throw new Error(`No alignment named ${o} in ${n.uri}`)}e.setInit(void 0)}catch(a){e.setError(a),console.error(a)}})()}}function Dv(e){let t=!1;return()=>{let r=pv({model:e});r!==void 0?(e.setMousePos(r),t=!0):t&&(e.setMousePos(void 0),t=!1)}}function Nv(e){let t=!1;return()=>{let{connectedViewId:r,transcriptToMsaMap:n,querySeqName:o}=e;if(!r||!n)return;let i=new Set;for(let s of Bv((0,Qv.getSession)(e).views))for(let c of s.structures){if(c.connectedViewId!==r)continue;let l=c.hoverGenomeHighlights;if(!l||l.length===0)continue;let{g2p:A}=n;for(let u of l)for(let m=u.start;m<u.end;m++){let d=A[m];if(d!==void 0){let g=e.seqPosToGlobalCol(o,d);i.add(g)}}}let a=Array.from(i).map(s=>e.globalColToVisibleCol(s)).filter(s=>s!==void 0);a.length>0?(e.setHighlightedColumns(a),t=!0):t&&(e.setHighlightedColumns(e.highlightColumns?.length?e.highlightColumns:void 0),t=!1)}}function Lv(){bv().catch(e=>{console.error("Failed to cleanup old MSA data:",e)})}function iA({model:e,coord:t}){let{querySeqName:r,transcriptToMsaMap:n,mafRegion:o}=e,i=e.rows.find(s=>s[0]===r)?.[1];if(!i)return;let a=Sv(i,t);if(a!==void 0){if(o){let s=o.start+a;return s<o.end?{refName:o.refName,start:s,end:s+1}:void 0}if(n){let{refName:s,p2g:c}=n,l=c[a],A=c[a+1];return l!==void 0&&A!==void 0?{refName:s,start:Math.min(l,A),end:Math.max(l,A)}:void 0}}}function np(){return Pe.types.compose(Rv.BaseViewModel,Jl(),Pe.types.model("MsaView",{connectedViewId:Pe.types.maybe(Pe.types.string),connectedFeature:Pe.types.frozen(),blastParams:Pe.types.frozen(),querySeqName:Pe.types.stripDefault(Pe.types.string,"QUERY"),uniprotId:Pe.types.maybe(Pe.types.string),zoomToBaseLevel:Pe.types.stripDefault(Pe.types.boolean,!1),init:Pe.types.frozen(),dataStoreId:Pe.types.maybe(Pe.types.string),mafRegion:Pe.types.frozen()})).volatile(()=>({rid:void 0,progress:"",error:void 0,loadingStoredData:!1,isStoringData:!1,domainsRequested:!1})).views(e=>({getRowByName(t){return e.rows.find(r=>r[0]===t)},getSequenceByRowName(t){return e.rows.find(r=>r[0]===t)?.[1]}})).views(e=>({get transcriptToMsaMap(){return e.connectedFeature?Sg(e.connectedFeature):void 0},get connectedView(){let{views:t}=(0,Fv.getSession)(e);return t.find(r=>r.id===e.connectedViewId)}})).views(e=>({get connectedHoverHighlight(){let{mouseCol:t}=e;return t===void 0?void 0:iA({model:e,coord:t})},get connectedClickHighlight(){let{mouseClickCol:t}=e;return t===void 0?void 0:iA({model:e,coord:t})},get connectedHighlights(){return[this.connectedHoverHighlight,this.connectedClickHighlight].filter(t=>t!==void 0)}})).actions(e=>({setZoomToBaseLevel(t){e.zoomToBaseLevel=t},setError(t){e.error=t},setProgress(t){e.progress=t},setRid(t){e.rid=t},setBlastParams(t){e.blastParams=t},setInit(t){e.init=t},setQuerySeqName(t){e.querySeqName=t},setUniprotId(t){e.uniprotId=t},setDataStoreId(t){e.dataStoreId=t},setMafRegion(t){e.mafRegion=t},setLoadingStoredData(t){e.loadingStoredData=t},setIsStoringData(t){e.isStoringData=t},setDomainsRequested(t){e.domainsRequested=t},handleMsaClick(t){let{connectedView:r,zoomToBaseLevel:n}=e,o=iA({model:e,coord:t});!o||!r||(n?r.navTo(o):r.centerAt(o.start,o.refName))}})).actions(e=>{let t=e.setMouseClickPos.bind(e);return{setMouseClickPos(r,n){t(r,n),r!==void 0&&e.handleMsaClick(r)}}}).views(e=>({extraViewMenuItems(){return[{label:"Zoom to base level on click?",checked:e.zoomToBaseLevel,type:"checkbox",onClick:()=>{e.setZoomToBaseLevel(!e.zoomToBaseLevel)}}]}})).actions(e=>({afterCreate(){Lv();for(let t of[vv,Mv,_v,kv,Tv])(0,Pe.addDisposer)(e,(0,aA.autorun)(()=>{t(e)}));(0,Pe.addDisposer)(e,(0,aA.autorun)(Dv(e))),(0,Pe.addDisposer)(e,(0,aA.autorun)(Nv(e)))}}))}function Yi(e){return e.type==="MsaView"}var D5=(0,ip.observer)(function({model:e}){let{hovered:t,views:r}=(0,Pv.getSession)(e);return r.some(o=>Yi(o)&&o.connectedViewId===e.id)&&Zn(t)?op.default.createElement(N5,{model:e,hovered:t}):null}),N5=(0,ip.observer)(function({model:e,hovered:t}){let{classes:r}=Ts(),{offsetPx:n}=e,{coord:o,refName:i}=t.hoverPosition,a=e.bpToPx({refName:i,coord:o-1}),s=e.bpToPx({refName:i,coord:o});if(a&&s){let c=Math.max(Math.abs(s.offsetPx-a.offsetPx),4),l=Math.min(a.offsetPx,s.offsetPx)-n;return op.default.createElement("div",{className:r.highlight,style:{left:l,width:c}})}return null}),Ov=D5;var ms=f(M()),Gv=f(de()),ap=f(H());var L5=(0,ap.observer)(function({model:t}){let{views:r,hovered:n}=(0,Gv.getSession)(t),o=r.filter(Yi).find(c=>c.connectedViewId===t.id),i=o?.connectedClickHighlight,a=Zn(n)?void 0:o?.connectedHoverHighlight,s=[i,a].filter(c=>c!==void 0);return s.length?ms.default.createElement(R5,{model:t,highlights:s}):null}),R5=(0,ap.observer)(function({model:e,highlights:t}){let{classes:r}=Ts(),{offsetPx:n}=e;return ms.default.createElement(ms.default.Fragment,null,t.map((o,i)=>{let a=e.bpToPx({refName:o.refName,coord:o.start}),s=e.bpToPx({refName:o.refName,coord:o.end});if(a&&s){let c=Math.max(Math.abs(s.offsetPx-a.offsetPx),4),l=Math.min(a.offsetPx,s.offsetPx)-n;return ms.default.createElement("div",{key:`${o.refName}-${o.start}-${o.end}-${i}`,className:r.highlight,style:{left:l,width:c}})}return null}))}),Uv=L5;var F5=(0,Hv.observer)(function({model:t}){return ps.default.createElement(ps.default.Fragment,null,ps.default.createElement(Uv,{model:t}),ps.default.createElement(Ov,{model:t}))}),jv=F5;function sp(e){e.addToExtensionPoint("LinearGenomeView-TracksContainerComponent",(t,{model:r})=>{let{views:n}=(0,Jv.getSession)(r);return n.some(i=>Yi(i)&&i.connectedViewId===r.id)?[...t,qv.default.createElement(jv,{key:"highlight_protein_viewer_msaview",model:r})]:t})}var Zv=f(YA());var Vv=f(Jo());function cp(e){let t=e.getAdapterType("BgzipFastaAdapter");return(0,Vv.ConfigurationSchema)("BgzipFastaMsaAdapter",{msaRegex:{type:"string",defaultValue:"_"}},{baseConfiguration:t?.configSchema})}function lp(e){return e.addAdapterType(()=>new Zv.AdapterType({name:"BgzipFastaMsaAdapter",configSchema:cp(e),adapterMetadata:{hiddenFromGUI:!0},getAdapterClass:()=>Promise.resolve().then(()=>(Xv(),Kv)).then(t=>t.default)}))}var _A=f(de());me();var e2=f(R(),1),t2=(0,j.createSvgIcon)((0,e2.jsx)("path",{d:"M19 13h-6v6h-2v-6H5v-2h6V5h2v6h6z"}),"Add");var Lt=f(M()),_M=f(Ne()),TM=f(de()),ta=f(O());var re=f(M()),Mp=f(Ne()),cr=f(O()),R2=f(H()),F2=f(wt());var r2=f(de());function n2({newViewTitle:e,view:t,feature:r,msaFilehandle:n,treeFilehandle:o,querySeqName:i,data:a}){(0,r2.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,connectedViewId:t.id,connectedFeature:r.toJSON(),msaFilehandle:n,treeFilehandle:o,querySeqName:i,data:a})}var Ap=f(M()),o2=f(O());function P5({children:e,...t}){return Ap.default.createElement("div",null,Ap.default.createElement(o2.TextField,{...t},e))}var ct=P5;var up=f(M()),i2=f(Ne()),a2=f(O()),s2=f(wt()),O5=(0,s2.makeStyles)()({dialogContent:{width:"80em"}});function xr({error:e,children:t}){let{classes:r}=O5();return up.default.createElement(a2.DialogContent,{className:r.dialogContent},e?up.default.createElement(i2.ErrorMessage,{error:e}):null,t)}var cA=f(M()),gs=f(O());function dn({onSubmit:e,onCancel:t,submitDisabled:r,submitLabel:n="Submit",cancelLabel:o="Cancel"}){return cA.default.createElement(gs.DialogActions,null,cA.default.createElement(gs.Button,{color:"primary",variant:"contained",disabled:r,onClick:()=>{e()}},n),cA.default.createElement(gs.Button,{color:"secondary",variant:"contained",onClick:()=>{t()}},o))}var yr=f(M()),zi=f(O()),A2=f(wt());var c2=f(M()),l2=f(wt());var G5=(0,l2.makeStyles)()({textAreaFont:{fontFamily:"Courier New"}});function fp({value:e}){let{classes:t}=G5();return c2.default.createElement(ct,{variant:"outlined",multiline:!0,minRows:5,maxRows:10,fullWidth:!0,value:e,slotProps:{input:{readOnly:!0,classes:{input:t.textAreaFont}}}})}var U5=(0,A2.makeStyles)()({flex:{display:"flex"},minWidth:{minWidth:300},centered:{alignContent:"center",marginLeft:20}});function wr({feature:e,options:t,selectedId:r,selectedTranscript:n,setSelectedId:o,proteinSequence:i,validIds:a}){let{classes:s}=U5(),[c,l]=(0,yr.useState)(!1);return yr.default.createElement(yr.default.Fragment,null,yr.default.createElement("div",{className:s.flex},yr.default.createElement(zi.TextField,{variant:"outlined",label:`Choose isoform of ${Mo(e)}`,select:!0,className:s.minWidth,value:r,onChange:A=>{o(A.target.value)}},t.map(A=>{let u=a?a.some(g=>Vi(A,g)):!0,{len:m,mod:d}=Vl(A);return yr.default.createElement(zi.MenuItem,{value:vo(A),key:A.id(),disabled:!u},zl(A)," (",m," aa)"," ",d?" (possible fragment)":"",a?u?" (has data)":" (no data)":"")})),yr.default.createElement("div",{className:s.centered},yr.default.createElement(zi.Button,{variant:"contained",color:"primary",onClick:()=>{l(!c)}},c?"Hide sequence":"Show sequence"))),c?yr.default.createElement(fp,{value:i?`>${zl(n)}
-${i}`:"Loading..."}):null)}var yA=f(M());var zn=f(de()),H5=(0,zn.generateCodonTable)(zn.defaultCodonTable);function j5(e,t){return e.map(r=>t.slice(r.start,r.end)).join("")}function q5({cds:e,sequence:t}){let r=j5(e,t),n="";for(let o=0;o<r.length;o+=3)n+=H5[r.slice(o,o+3)]??"&";return n}function J5(e,t){return e.map(r=>({...r,start:t-r.end,end:t-r.start})).toSorted((r,n)=>r.start-n.start)}function u2({feature:e,seq:t}){let{subfeatures:r,start:n,strand:o}=e.toJSON(),i=(0,zn.dedupe)(r?.toSorted((a,s)=>a.start-s.start).map(a=>({...a,start:a.start-n,end:a.end-n})).filter(a=>a.type==="CDS")??[],a=>`${a.start}-${a.end}`);return q5({cds:o===-1?J5(i,t.length):i,sequence:o===-1?(0,zn.revcom)(t):t})}var D2=f(de());var ze=f(M(),1),vp=f(p2(),1);var lt=f(M(),1);var Wn={};dt(Wn,{ERROR_REVALIDATE_EVENT:()=>t3,FOCUS_EVENT:()=>g2,MUTATE_EVENT:()=>C2,RECONNECT_EVENT:()=>h2});var g2=0,h2=1,C2=2,t3=3;var E2=Object.prototype.hasOwnProperty;function lA(e,t){var r,n;if(e===t)return!0;if(e&&t&&(r=e.constructor)===t.constructor){if(r===Date)return e.getTime()===t.getTime();if(r===RegExp)return e.toString()===t.toString();if(r===Array){if((n=e.length)===t.length)for(;n--&&lA(e[n],t[n]););return n===-1}if(!r||typeof e=="object"){n=0;for(r in e)if(E2.call(e,r)&&++n&&!E2.call(t,r)||!(r in t)||!lA(e[r],t[r]))return!1;return Object.keys(t).length===n}}return e!==e&&t!==t}var br=new WeakMap,Br=()=>{},qe=Br(),$i=Object,z=e=>e===qe,Wt=e=>typeof e=="function",Sr=(e,t)=>({...e,...t}),pA=e=>Wt(e.then),mp={},AA={},xp="undefined",Ki=typeof window!=xp,fA=typeof document!=xp,x2=Ki&&"Deno"in window,y2=()=>Ki&&typeof window.requestAnimationFrame!=xp,gA=(e,t)=>{let r=br.get(e);return[()=>!z(t)&&e.get(t)||mp,n=>{if(!z(t)){let o=e.get(t);t in AA||(AA[t]=o),r[5](t,Sr(o,n),o||mp)}},r[6],()=>!z(t)&&t in AA?AA[t]:!z(t)&&e.get(t)||mp]},hp=!0,r3=()=>hp,[Cp,Ep]=Ki&&window.addEventListener?[window.addEventListener.bind(window),window.removeEventListener.bind(window)]:[Br,Br],n3=()=>{let e=fA&&document.visibilityState;return z(e)||e!=="hidden"},o3=e=>(fA&&document.addEventListener("visibilitychange",e),Cp("focus",e),()=>{fA&&document.removeEventListener("visibilitychange",e),Ep("focus",e)}),i3=e=>{let t=()=>{hp=!0,e()},r=()=>{hp=!1};return Cp("online",t),Cp("offline",r),()=>{Ep("online",t),Ep("offline",r)}},w2={isOnline:r3,isVisible:n3},b2={initFocus:o3,initReconnect:i3},hA=!lt.default.useId,$n=!Ki||x2,yp=e=>y2()?window.requestAnimationFrame(e):setTimeout(e,1),Xi=$n?lt.useEffect:lt.useLayoutEffect,pp=typeof navigator<"u"&&navigator.connection,Ip=!$n&&pp&&(["slow-2g","2g"].includes(pp.effectiveType)||pp.saveData),uA=new WeakMap,a3=e=>$i.prototype.toString.call(e),gp=(e,t)=>e===`[object ${t}]`,s3=0,dA=e=>{let t=typeof e,r=a3(e),n=gp(r,"Date"),o=gp(r,"RegExp"),i=gp(r,"Object"),a,s;if($i(e)===e&&!n&&!o){if(a=uA.get(e),a)return a;if(a=++s3+"~",uA.set(e,a),Array.isArray(e)){for(a="@",s=0;s<e.length;s++)a+=dA(e[s])+",";uA.set(e,a)}if(i){a="#";let c=$i.keys(e).sort();for(;!z(s=c.pop());)z(e[s])||(a+=s+":"+dA(e[s])+",");uA.set(e,a)}}else a=n?e.toJSON():t=="symbol"?e.toString():t=="string"?JSON.stringify(e):""+e;return a},Cs=e=>{if(Wt(e))try{e=e()}catch{e=""}let t=e;return e=typeof e=="string"?e:(Array.isArray(e)?e.length:e)?dA(e):"",[e,t]},c3=0,hs=()=>++c3;async function CA(...e){let[t,r,n,o]=e,i=Sr({populateCache:!0,throwOnError:!0},typeof o=="boolean"?{revalidate:o}:o||{}),a=i.populateCache,s=i.rollbackOnError,c=i.optimisticData,l=m=>typeof s=="function"?s(m):s!==!1,A=i.throwOnError;if(Wt(r)){let m=r,d=[],g=t.keys();for(let C of g)!/^\$(inf|sub)\$/.test(C)&&m(t.get(C)._k)&&d.push(C);return Promise.all(d.map(u))}return u(r);async function u(m){let[d]=Cs(m);if(!d)return;let[g,C]=gA(t,d),[y,I,E,b]=br.get(t),x=()=>{let W=y[d];return(Wt(i.revalidate)?i.revalidate(g().data,m):i.revalidate!==!1)&&(delete E[d],delete b[d],W&&W[0])?W[0](2).then(()=>g().data):g().data};if(e.length<3)return x();let w=n,Q,S=!1,k=hs();I[d]=[k,0];let N=!z(c),_=g(),v=_.data,L=_._c,U=z(L)?v:L;if(N&&(c=Wt(c)?c(U,v):c,C({data:c,_c:U})),Wt(w))try{w=w(U)}catch(W){Q=W,S=!0}if(w&&pA(w))if(w=await w.catch(W=>{Q=W,S=!0}),k!==I[d][0]){if(S)throw Q;return w}else S&&N&&l(Q)&&(a=!0,C({data:U,_c:qe}));if(a&&!S)if(Wt(a)){let W=a(w,U);C({data:W,error:qe,_c:qe})}else C({data:w,error:qe,_c:qe});if(I[d][1]=hs(),Promise.resolve(x()).then(()=>{C({_c:qe})}),S){if(A)throw Q;return}return w}}var I2=(e,t)=>{for(let r in e)e[r][0]&&e[r][0](t)},wp=(e,t)=>{if(!br.has(e)){let r=Sr(b2,t),n=Object.create(null),o=CA.bind(qe,e),i=Br,a=Object.create(null),s=(A,u)=>{let m=a[A]||[];return a[A]=m,m.push(u),()=>{let d=m.indexOf(u);d>=0&&(m[d]=m[m.length-1],m.pop())}},c=(A,u,m)=>{e.set(A,u);let d=a[A];if(d)for(let g of d)g(u,m)},l=()=>{if(!br.has(e)&&(br.set(e,[n,Object.create(null),Object.create(null),Object.create(null),o,c,s]),!$n)){let A=r.initFocus(setTimeout.bind(qe,I2.bind(qe,n,0))),u=r.initReconnect(setTimeout.bind(qe,I2.bind(qe,n,1)));i=()=>{A&&A(),u&&u(),br.delete(e)}}};return l(),[e,o,l,i]}return[e,br.get(e)[4]]},l3=(e,t,r,n,o)=>{let i=r.errorRetryCount,a=o.retryCount,s=~~((Math.random()+.5)*(1<<(a<8?a:8)))*r.errorRetryInterval;!z(i)&&a>i||setTimeout(n,s,o)},B2=lA,[EA,S2]=wp(new Map),IA=Sr({onLoadingSlow:Br,onSuccess:Br,onError:Br,onErrorRetry:l3,onDiscarded:Br,revalidateOnFocus:!0,revalidateOnReconnect:!0,revalidateIfStale:!0,shouldRetryOnError:!0,errorRetryInterval:Ip?1e4:5e3,focusThrottleInterval:5*1e3,dedupingInterval:2*1e3,loadingTimeout:Ip?5e3:3e3,compare:B2,isPaused:()=>!1,cache:EA,mutate:S2,fallback:{}},w2),bp=(e,t)=>{let r=Sr(e,t);if(t){let{use:n,fallback:o}=e,{use:i,fallback:a}=t;n&&i&&(r.use=n.concat(i)),o&&a&&(r.fallback=Sr(o,a))}return r},mA=(0,lt.createContext)({}),Bp=e=>{let{value:t}=e,r=(0,lt.useContext)(mA),n=Wt(t),o=(0,lt.useMemo)(()=>n?t(r):t,[n,r,t]),i=(0,lt.useMemo)(()=>n?o:bp(r,o),[n,r,o]),a=o&&o.provider,s=(0,lt.useRef)(qe);a&&!s.current&&(s.current=wp(a(i.cache||EA),o));let c=s.current;return c&&(i.cache=c[0],i.mutate=c[1]),Xi(()=>{if(c)return c[2]&&c[2](),c[3]},[]),(0,lt.createElement)(mA.Provider,Sr(e,{value:i}))};var Q2="$inf$";var Zi=f(M(),1);var v2=Ki&&window.__SWR_DEVTOOLS_USE__,A3=v2?window.__SWR_DEVTOOLS_USE__:[],u3=()=>{v2&&(window.__SWR_DEVTOOLS_REACT__=Zi.default)},f3=e=>Wt(e[1])?[e[0],e[1],e[2]||{}]:[e[0],null,(e[1]===null?e[2]:e[1])||{}],d3=()=>{let e=(0,Zi.useContext)(mA);return(0,Zi.useMemo)(()=>Sr(IA,e),[e])};var m3=e=>(t,r,n)=>e(t,r&&((...i)=>{let[a]=Cs(t),[,,,s]=br.get(EA);if(a.startsWith(Q2))return r(...i);let c=s[a];return z(c)?r(...i):(delete s[a],c)}),n),p3=A3.concat(m3),M2=e=>function(...r){let n=d3(),[o,i,a]=f3(r),s=bp(n,a),c=e,{use:l}=s,A=(l||[]).concat(p3);for(let u=A.length;u--;)c=A[u](c);return c(o,i||s.fetcher||null,s)},_2=(e,t,r)=>{let n=t[e]||(t[e]=[]);return n.push(r),()=>{let o=n.indexOf(r);o>=0&&(n[o]=n[n.length-1],n.pop())}};u3();var g3=()=>{},vW=g3();var Sp=ze.default.use||(e=>{switch(e.status){case"pending":throw e;case"fulfilled":return e.value;case"rejected":throw e.reason;default:throw e.status="pending",e.then(t=>{e.status="fulfilled",e.value=t},t=>{e.status="rejected",e.reason=t}),e}}),Qp={dedupe:!0},xA=Promise.resolve(qe);xA.status="fulfilled";xA.value=qe;var h3=()=>Br,C3=(e,t,r)=>{let{cache:n,compare:o,suspense:i,fallbackData:a,revalidateOnMount:s,revalidateIfStale:c,refreshInterval:l,refreshWhenHidden:A,refreshWhenOffline:u,keepPreviousData:m,strictServerPrefetchWarning:d}=r,[g,C,y,I]=br.get(n),[E,b]=Cs(e),x=(0,ze.useRef)(!1),w=(0,ze.useRef)(!1),Q=(0,ze.useRef)(E),S=(0,ze.useRef)(t),k=(0,ze.useRef)(r),N=()=>k.current,_=()=>N().isVisible()&&N().isOnline(),[v,L,U,W]=gA(n,E),se=(0,ze.useRef)({}).current,Te=z(a)?z(r.fallback)?qe:r.fallback[E]:a,Oe=(ne,te)=>{for(let be in se){let Ce=be;if(Ce==="data"){if(!o(ne[Ce],te[Ce])&&(!z(ne[Ce])||!o(Lo,te[Ce])))return!1}else if(te[Ce]!==ne[Ce])return!1}return!0},pn=!x.current,Kn=(0,ze.useMemo)(()=>{let ne=v(),te=W(),be=ce=>{let Ge=Sr(ce);return delete Ge._k,(()=>{if(!E||!t||N().isPaused())return!1;if(pn&&!z(s))return s;let Xr=z(Te)?Ge.data:Te;return i?z(Xr)||c:z(Xr)||c})()?{isValidating:!0,isLoading:!0,...Ge}:Ge},Ce=be(ne),Rt=ne===te?Ce:be(te),xt=Ce;return[()=>{let ce=be(v());return Oe(ce,xt)?(xt.data=ce.data,xt.isLoading=ce.isLoading,xt.isValidating=ce.isValidating,xt.error=ce.error,xt):(xt=ce,ce)},()=>Rt]},[n,E]),It=(0,vp.useSyncExternalStore)((0,ze.useCallback)(ne=>U(E,(te,be)=>{Oe(be,te)||ne()}),[n,E]),Kn[0],Kn[1]),Ae=g[E]&&g[E].length>0,gn=It.data,$r=z(gn)?Te&&pA(Te)?Sp(Te):Te:gn,No=It.error,ra=(0,ze.useRef)($r),Lo=m?z(gn)?z(ra.current)?$r:ra.current:gn:$r,Kr=E&&z($r),hn=(0,ze.useRef)(null);!$n&&(0,vp.useSyncExternalStore)(h3,()=>(hn.current=!1,hn),()=>(hn.current=!0,hn));let NA=hn.current;d&&NA&&!i&&Kr&&console.warn(`Missing pre-initiated data for serialized key "${E}" during server-side rendering. Data fetching should be initiated on the server and provided to SWR via fallback data. You can set "strictServerPrefetchWarning: false" to disable this warning.`);let na=!E||!t||N().isPaused()||Ae&&!z(No)?!1:pn&&!z(s)?s:i?z($r)?!1:c:z($r)||c,ge=pn&&na,ws=z(It.isValidating)?ge:It.isValidating,we=z(It.isLoading)?ge:It.isLoading,Cn=(0,ze.useCallback)(async ne=>{let te=S.current;if(!E||!te||w.current||N().isPaused())return!1;let be,Ce,Rt=!0,xt=ne||{},ce=!y[E]||!xt.dedupe,Ge=()=>hA?!w.current&&E===Q.current&&x.current:E===Q.current,Ft={isValidating:!1,isLoading:!1},Xr=()=>{L(Ft)},Fo=()=>{let At=y[E];At&&At[1]===Ce&&delete y[E]},Po={isValidating:!0};z(v().data)&&(Po.isLoading=!0);try{if(ce&&(L(Po),r.loadingTimeout&&z(v().data)&&setTimeout(()=>{Rt&&Ge()&&N().onLoadingSlow(E,r)},r.loadingTimeout),y[E]=[te(b),hs()]),[be,Ce]=y[E],be=await be,ce&&setTimeout(Fo,r.dedupingInterval),!y[E]||y[E][1]!==Ce)return ce&&Ge()&&N().onDiscarded(E),!1;Ft.error=qe;let At=C[E];if(!z(At)&&(Ce<=At[0]||Ce<=At[1]||At[1]===0))return Xr(),ce&&Ge()&&N().onDiscarded(E),!1;let ut=v().data;Ft.data=o(ut,be)?ut:be,ce&&Ge()&&N().onSuccess(be,E,r)}catch(At){Fo();let ut=N(),{shouldRetryOnError:En}=ut;ut.isPaused()||(Ft.error=At,ce&&Ge()&&(ut.onError(At,E,ut),(En===!0||Wt(En)&&En(At))&&(!N().revalidateOnFocus||!N().revalidateOnReconnect||_())&&ut.onErrorRetry(At,E,ut,Oo=>{let Go=g[E];Go&&Go[0]&&Go[0](Wn.ERROR_REVALIDATE_EVENT,Oo)},{retryCount:(xt.retryCount||0)+1,dedupe:!0})))}return Rt=!1,Xr(),!0},[E,n]),he=(0,ze.useCallback)((...ne)=>CA(n,Q.current,...ne),[]);if(Xi(()=>{S.current=t,k.current=r,z(gn)||(ra.current=gn)}),Xi(()=>{if(!E)return;let ne=Cn.bind(qe,Qp),te=0;N().revalidateOnFocus&&(te=Date.now()+N().focusThrottleInterval);let Ce=_2(E,g,(Rt,xt={})=>{if(Rt==Wn.FOCUS_EVENT){let ce=Date.now();N().revalidateOnFocus&&ce>te&&_()&&(te=ce+N().focusThrottleInterval,ne())}else if(Rt==Wn.RECONNECT_EVENT)N().revalidateOnReconnect&&_()&&ne();else{if(Rt==Wn.MUTATE_EVENT)return Cn();if(Rt==Wn.ERROR_REVALIDATE_EVENT)return Cn(xt)}});return w.current=!1,Q.current=E,x.current=!0,L({_k:b}),na&&(y[E]||(z($r)||$n?ne():yp(ne))),()=>{w.current=!0,Ce()}},[E]),Xi(()=>{let ne;function te(){let Ce=Wt(l)?l(v().data):l;Ce&&ne!==-1&&(ne=setTimeout(be,Ce))}function be(){!v().error&&(A||N().isVisible())&&(u||N().isOnline())?Cn(Qp).then(te):te()}return te(),()=>{ne&&(clearTimeout(ne),ne=-1)}},[l,A,u,E]),(0,ze.useDebugValue)(Lo),i){if(!hA&&$n&&Kr)throw new Error("Fallback data is required when using Suspense in SSR.");Kr&&(S.current=t,k.current=r,w.current=!1);let ne=I[E],te=!z(ne)&&Kr?he(ne):xA;if(Sp(te),!z(No)&&Kr)throw No;let be=Kr?Cn(Qp):xA;!z(Lo)&&Kr&&(be.status="fulfilled",be.value=!0),Sp(be)}return{mutate:he,get data(){return se.data=!0,Lo},get error(){return se.error=!0,No},get isValidating(){return se.isValidating=!0,ws},get isLoading(){return se.isLoading=!0,we}}},MW=$i.defineProperty(Bp,"defaultValue",{value:IA}),_o=M2(C3);var T2=f(Jo());async function k2({start:e,end:t,refName:r,session:n,assemblyName:o}){let{assemblyManager:i,rpcManager:a}=n,s=await i.waitForAssembly(o);if(!s)throw new Error("assembly not found");let c="getSequence";return(await a.call(c,"CoreGetFeatures",{adapterConfig:(0,T2.getConf)(s,["sequence","adapter"]),sessionId:c,regions:[{start:e,end:t,refName:s.getCanonicalRefName(r),assemblyName:o}]}))[0]?.get("seq")??""}var To={revalidateOnFocus:!1,revalidateOnReconnect:!1,revalidateIfStale:!1,refreshWhenHidden:!1,refreshWhenOffline:!1,shouldRetryOnError:!1};async function E3({feature:e,assemblyName:t,view:r}){let n=(0,D2.getSession)(r),{start:o,end:i,refName:a}=e.toJSON();return{seq:await k2({start:o,end:i,refName:a,assemblyName:t,session:n})}}function N2({view:e,feature:t}){let r=e?.assemblyNames?.[0],n=t&&r?{feature:t,assemblyName:r,view:e}:void 0,{data:o,error:i}=_o(n?[n.feature.id(),n.assemblyName,"feature-sequence"]:null,()=>E3(n),To);return{sequence:o,error:i}}function L2({view:e,feature:t}){let{sequence:r,error:n}=N2({view:e,feature:t});return{proteinSequence:r&&t?u2({seq:r.seq,feature:t}):"",sequence:r,error:n}}function I3(e,t,r){if(!r?.length)return e;let n=a=>r.some(s=>Vi(a,s)),o=t.find(a=>vo(a)===e);if(o&&n(o))return e;let i=t.find(n);return i?vo(i):e}function zr({feature:e,view:t,validIds:r}){let n=(0,yA.useMemo)(()=>$l(e),[e]),[o,i]=(0,yA.useState)(()=>vo(n[0])),a=I3(o,n,r),s=n.find(A=>vo(A)===a),{proteinSequence:c,error:l}=L2({view:t,feature:s});return{options:n,selectedId:a,setSelectedId:i,selectedTranscript:s,proteinSequence:c,error:l,validIds:r}}var x3=(0,F2.makeStyles)()({textAreaFont:{fontFamily:"Courier New"},inputContainer:{marginBottom:30},fileContainer:{maxWidth:500},msaInput:{marginBottom:20},queryNameInput:{marginTop:20},warningAlert:{marginTop:10}}),y3=(0,R2.observer)(function({model:t,feature:r,handleClose:n}){let o=sr(t),{classes:i}=x3(),[a,s]=(0,re.useState)(),[c,l]=(0,re.useState)("file"),[A,u]=(0,re.useState)(""),[m,d]=(0,re.useState)(""),[g,C]=(0,re.useState)(),[y,I]=(0,re.useState)(),[E,b]=(0,re.useState)(""),x=zr({feature:r,view:o}),{selectedTranscript:w,error:Q}=x;return re.default.createElement(re.default.Fragment,null,re.default.createElement(xr,{error:a??Q},re.default.createElement(cr.FormControl,{component:"fieldset"},re.default.createElement(cr.RadioGroup,{row:!0,value:c,onChange:k=>{l(k.target.value)}},re.default.createElement(cr.FormControlLabel,{value:"file",control:re.default.createElement(cr.Radio,null),label:"Open files"}),re.default.createElement(cr.FormControlLabel,{value:"text",control:re.default.createElement(cr.Radio,null),label:"Paste text"}))),re.default.createElement("div",{className:i.inputContainer},c==="file"?re.default.createElement("div",{className:i.fileContainer},re.default.createElement(Mp.FileSelector,{name:"MSA File .aln (Clustal), .fa/.mfa (aligned FASTA), .stock (Stockholm), etc)",inline:!0,location:g,setLocation:C}),re.default.createElement(Mp.FileSelector,{name:"Tree file .nh (Newick) or .asn (NCBI COBALT ASN.1)",inline:!0,location:y,setLocation:I})):re.default.createElement(re.default.Fragment,null,re.default.createElement(ct,{variant:"outlined",name:"MSA",multiline:!0,minRows:5,className:i.msaInput,maxRows:10,fullWidth:!0,placeholder:"Paste MSA here",value:A,onChange:k=>{u(k.target.value)}}),re.default.createElement(ct,{variant:"outlined",name:"Tree",multiline:!0,minRows:5,maxRows:10,fullWidth:!0,placeholder:"Paste newick tree (optional)",value:m,onChange:k=>{d(k.target.value)}}))),re.default.createElement(wr,{feature:r,...x}),re.default.createElement(ct,{variant:"outlined",name:"MSA row name",fullWidth:!0,required:!0,className:i.queryNameInput,placeholder:"Row name in MSA that corresponds to the selected transcript",helperText:"Required: Specify the name of the row in your MSA that should be aligned with the selected transcript",value:E,onChange:k=>{b(k.target.value)}}),E.trim()?null:re.default.createElement(cr.Alert,{severity:"warning",className:i.warningAlert},"Without specifying the MSA row name, clicking on the MSA will not navigate to the corresponding genome position, and hovering highlights will not work.")),re.default.createElement(dn,{submitDisabled:!w||c==="file"&&!g||c==="text"&&!A.trim(),onSubmit:()=>{try{w&&(s(void 0),n2({newViewTitle:Mo(w),view:o,feature:w,querySeqName:E.trim(),...c==="file"?{msaFilehandle:g,treeFilehandle:y}:{data:{msa:A,tree:m}}}),n())}catch(k){console.error(k),s(k)}},onCancel:n}))}),P2=y3;var vr=f(M()),mM=f(de());me();var O2=f(R(),1),G2=(0,j.createSvgIcon)((0,O2.jsx)("path",{d:"M19.14 12.94c.04-.3.06-.61.06-.94 0-.32-.02-.64-.07-.94l2.03-1.58c.18-.14.23-.41.12-.61l-1.92-3.32c-.12-.22-.37-.29-.59-.22l-2.39.96c-.5-.38-1.03-.7-1.62-.94l-.36-2.54c-.04-.24-.24-.41-.48-.41h-3.84c-.24 0-.43.17-.47.41l-.36 2.54c-.59.24-1.13.57-1.62.94l-2.39-.96c-.22-.08-.47 0-.59.22L2.74 8.87c-.12.21-.08.47.12.61l2.03 1.58c-.05.3-.09.63-.09.94s.02.64.07.94l-2.03 1.58c-.18.14-.23.41-.12.61l1.92 3.32c.12.22.37.29.59.22l2.39-.96c.5.38 1.03.7 1.62.94l.36 2.54c.05.24.24.41.48.41h3.84c.24 0 .44-.17.47-.41l.36-2.54c.59-.24 1.13-.56 1.62-.94l2.39.96c.22.08.47 0 .59-.22l1.92-3.32c.12-.22.07-.47-.12-.61zM12 15.6c-1.98 0-3.6-1.62-3.6-3.6s1.62-3.6 3.6-3.6 3.6 1.62 3.6 3.6-1.62 3.6-3.6 3.6"}),"Settings");var pM=f(O()),gM=f(wt());var fe=f(M());Qm();var $t=f(O()),Z2=f(H()),eM=f(wt());var nt=f(M()),J2=f(Ne());me();var U2=f(R(),1),H2=(0,j.createSvgIcon)((0,U2.jsx)("path",{d:"M6 19c0 1.1.9 2 2 2h8c1.1 0 2-.9 2-2V7H6zM19 4h-3.5l-1-1h-5l-1 1H5v2h14z"}),"Delete");var ht=f(O()),V2=f(H()),Y2=f(wt());var _p=f(de());function wA({newViewTitle:e,view:t,feature:r,blastParams:n}){(0,_p.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,connectedViewId:t.id,connectedFeature:r.toJSON(),drawNodeBubbles:!0,colWidth:10,rowHeight:12,blastParams:n})}function j2({newViewTitle:e,view:t,cached:r,connectedFeature:n}){(0,_p.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,connectedViewId:t.id,connectedFeature:n,drawNodeBubbles:!0,colWidth:10,rowHeight:12,data:{msa:r.msa,tree:r.tree,treeMetadata:r.treeMetadata}})}function bA(e){let{data:t,error:r,isLoading:n,mutate:o}=_o(`cached-blast-${e.join(",")}`,async()=>(await ev()).filter(c=>c.geneId&&e.includes(c.geneId)),To);return{results:t??[],error:r,isLoading:n,handleDelete:async s=>{await tv(s),await o(c=>c?.filter(l=>l.id!==s)??[],!1)},handleClearAll:async()=>{await rv(),await o([],!1)}}}var w3=(0,Y2.makeStyles)()({header:{display:"flex",justifyContent:"space-between",alignItems:"center",marginBottom:8},resultList:{maxHeight:300,overflow:"auto"}});function q2(e){let t=[e.geneName,e.transcriptName!==e.geneName?e.transcriptName:void 0].filter(r=>!!r);return t.length>0?t.join(" - "):e.geneId??e.transcriptId??"Unknown"}var b3=(0,V2.observer)(function({model:e,handleClose:t,feature:r}){let{classes:n}=w3(),o=sr(e),[i,a]=(0,nt.useState)(),s=(0,nt.useMemo)(()=>Xl(r),[r]),{results:c,error:l,isLoading:A,handleDelete:u,handleClearAll:m}=bA(s),d=C=>{let{transcriptId:y}=C,I=y?$l(r).find(E=>Vi(E,y)):void 0;j2({view:o,cached:C,newViewTitle:`BLAST - ${q2(C)}`,connectedFeature:I?.toJSON()}),t()},g=l??i;return g?nt.default.createElement(J2.ErrorMessage,{error:g}):A?nt.default.createElement(ht.Typography,null,"Loading cached results..."):c.length===0?nt.default.createElement(ht.Typography,{color:"textSecondary"},"No cached BLAST results found for this gene. Run a BLAST query to cache results."):nt.default.createElement("div",null,nt.default.createElement("div",{className:n.header},nt.default.createElement(ht.Typography,{variant:"subtitle1"},"Cached BLAST Results (",c.length,")"),nt.default.createElement(ht.Button,{size:"small",color:"error",onClick:async()=>{try{a(void 0),await m()}catch(C){a(C)}}},"Clear All")),nt.default.createElement(ht.List,{dense:!0,className:n.resultList},c.map(C=>nt.default.createElement(ht.ListItem,{key:C.id,disablePadding:!0,secondaryAction:nt.default.createElement(ht.IconButton,{edge:"end",size:"small",onClick:async y=>{y.stopPropagation();try{a(void 0),await u(C.id)}catch(I){a(I)}}},nt.default.createElement(H2,{fontSize:"small"}))},nt.default.createElement(ht.ListItemButton,{onClick:()=>{d(C)}},nt.default.createElement(ht.ListItemText,{primary:`${q2(C)} - ${C.blastDatabase}/${C.blastProgram} (${C.msaAlgorithm})`,secondary:`${new Date(C.timestamp).toLocaleString()} - Seq: ${C.proteinSequence.slice(0,30)}...`}))))))}),z2=b3;var Tp=f(M()),X2=f(O());var BA="https://blast.ncbi.nlm.nih.gov/Blast.cgi",W2=["clustalo","muscle","kalign","mafft"],$2=["nr","nr_cluster_seq"],K2=["blastp","quick-blastp"];function Es({value:e,onChange:t,className:r}){return Tp.default.createElement(ct,{variant:"outlined",label:"MSA Algorithm",className:r,select:!0,value:e,onChange:n=>{t(n.target.value)}},W2.map(n=>Tp.default.createElement(X2.MenuItem,{value:n,key:n},n)))}var B3=(0,eM.makeStyles)()({selectField:{width:150},databaseFieldContainer:{display:"flex"},clusterSeqMessage:{marginLeft:4,alignContent:"center"},cachedResultsAccordion:{marginTop:20},infoText:{marginTop:20}}),S3=(0,Z2.observer)(function({handleClose:e,feature:t,model:r,children:n,baseUrl:o}){let{classes:i}=B3(),a=sr(r),[s,c]=(0,fe.useState)(),[l,A]=(0,fe.useState)("nr"),[u,m]=(0,fe.useState)("clustalo"),[d,g]=(0,fe.useState)("quick-blastp"),C=(0,fe.useMemo)(()=>Xl(t),[t]),{results:y,error:I}=bA(C),E=zr({feature:t,view:a}),{selectedTranscript:b,proteinSequence:x}=E,w=E.error??s??I;return fe.default.createElement(fe.default.Fragment,null,fe.default.createElement(xr,{error:w},n,fe.default.createElement(ct,{variant:"outlined",label:"BLAST database",className:i.selectField,select:!0,value:l,onChange:Q=>{let S=Q.target.value;A(S),S==="nr_cluster_seq"&&g("blastp")}},$2.map(Q=>fe.default.createElement($t.MenuItem,{value:Q,key:Q},Q))),fe.default.createElement(Es,{className:i.selectField,value:u,onChange:m}),fe.default.createElement("div",{className:i.databaseFieldContainer},fe.default.createElement(ct,{variant:"outlined",label:"BLAST program",disabled:l==="nr_cluster_seq",className:i.selectField,select:!0,value:d,onChange:Q=>{g(Q.target.value)}},K2.map(Q=>fe.default.createElement($t.MenuItem,{value:Q,key:Q},Q))),l==="nr_cluster_seq"?fe.default.createElement($t.Typography,{variant:"subtitle2",className:i.clusterSeqMessage},"Can only use blastp on nr_cluster_seq"):null),fe.default.createElement(wr,{feature:t,...E}),fe.default.createElement($t.Typography,{className:i.infoText},"This panel will automatically submit a query to NCBI. Using blastp can take 10+ minutes to run, quick-blastp is generally a lot faster but is not available for the clustered database. After completion, all the hits will be run through a multiple sequence alignment. Note: we are not able to currently run NCBI COBALT automatically on the BLAST results, even though that is the method NCBI uses on their website. If you need a COBALT alignment, please use the manual approach of submitting BLAST yourself and downloading the resulting files"),y.length>0?fe.default.createElement($t.Accordion,{className:i.cachedResultsAccordion},fe.default.createElement($t.AccordionSummary,{expandIcon:fe.default.createElement(kl,null)},fe.default.createElement($t.Typography,null,"Previous BLAST Results")),fe.default.createElement($t.AccordionDetails,null,fe.default.createElement(z2,{model:r,handleClose:e,feature:t}))):null),fe.default.createElement(dn,{submitDisabled:!x,onSubmit:()=>{try{b&&(c(void 0),wA({feature:b,view:a,newViewTitle:Wl(t,b),blastParams:{baseUrl:o,blastProgram:d,blastDatabase:l,msaAlgorithm:u,selectedTranscript:b,proteinSequence:x}}),e())}catch(Q){console.error(Q),c(Q)}},onCancel:e}))}),tM=S3;var Wr=f(M()),aM=f(de()),ea=f(O()),sM=f(H()),cM=f(wt());SA();var Q3=(0,cM.makeStyles)()({ncbiLink:{wordBreak:"break-all",margin:30,maxWidth:600},infoText:{marginTop:20}}),v3=(0,sM.observer)(function({handleClose:e,feature:t,model:r,children:n,baseUrl:o}){let{classes:i}=Q3(),a=sr(r),s=zr({feature:t,view:a}),{proteinSequence:c,error:l}=s,A=Kl(c),u=`${o}?PAGE_TYPE=BlastSearch&PAGE=Proteins&PROGRAM=blastp&QUERY=${A}`,m=`${o}?PAGE_TYPE=BlastSearch&PAGE=Proteins&PROGRAM=blastp&QUERY=${(0,aM.shorten2)(A,10)}`;return Wr.default.createElement(Wr.default.Fragment,null,Wr.default.createElement(xr,{error:l},n,Wr.default.createElement(wr,{feature:t,...s}),c?Wr.default.createElement("div",{className:i.ncbiLink},"Link to NCBI BLAST: ",Wr.default.createElement(ko,{href:u},m)):null,Wr.default.createElement(ea.Typography,{className:i.infoText},`Click the link above and run your BLAST query, and once you have results, click "Multiple Alignment" at the top of the results page to be redirected to COBALT, NCBI's multiple sequence aligner. Once COBALT completes, you can download an MSA (.aln file) and optionally a Newick tree (.nh) and paste the results into JBrowse`)),Wr.default.createElement(ea.DialogActions,null,Wr.default.createElement(ea.Button,{color:"primary",variant:"contained",onClick:()=>{e()}},"Close")))}),lM=v3;var mn=f(M()),lr=f(O());function Dp({lookupMethod:e,setLookupMethod:t}){return mn.default.createElement(lr.FormControl,{component:"fieldset"},mn.default.createElement(lr.RadioGroup,{row:!0,value:e,onChange:r=>{t(r.target.value)}},mn.default.createElement(lr.FormControlLabel,{value:"automatic",control:mn.default.createElement(lr.Radio,null),label:"Automatic"}),mn.default.createElement(lr.FormControlLabel,{value:"rid",control:mn.default.createElement(lr.Radio,null),label:"Load from RID"}),mn.default.createElement(lr.FormControlLabel,{value:"manual",control:mn.default.createElement(lr.Radio,null),label:"Manual"})))}var Ct=f(M()),QA=f(O()),AM=f(H()),uM=f(wt());SA();var M3=(0,uM.makeStyles)()({marginBottom:{marginBottom:16},ridField:{width:150},infoText:{marginTop:20}}),_3=(0,AM.observer)(function({handleClose:e,feature:t,model:r,children:n,baseUrl:o}){let{classes:i}=M3(),a=sr(r),[s,c]=(0,Ct.useState)(),[l,A]=(0,Ct.useState)(""),[u,m]=(0,Ct.useState)("clustalo"),d=zr({feature:t,view:a}),{selectedTranscript:g,proteinSequence:C}=d,y=d.error??s,I=l.trim();return Ct.default.createElement(Ct.default.Fragment,null,Ct.default.createElement(xr,{error:y},n,Ct.default.createElement(QA.Typography,{variant:"body2",className:i.marginBottom},"Enter the RID (Request ID) from a previously submitted NCBI BLAST query. You can find the RID in the BLAST results page URL or at the top of the results page. RIDs are typically valid for 24-36 hours after submission."),Ct.default.createElement(ct,{variant:"outlined",label:"BLAST RID",placeholder:"e.g., ABC12345",fullWidth:!0,className:i.marginBottom,value:l,onChange:E=>{A(E.target.value)}}),I?Ct.default.createElement(QA.Typography,{variant:"body2",className:i.marginBottom},Ct.default.createElement(ko,{href:`${o}?CMD=Get&RID=${I}`},"View BLAST results on NCBI")):null,Ct.default.createElement(Es,{className:i.ridField,value:u,onChange:m}),Ct.default.createElement(wr,{feature:t,...d}),Ct.default.createElement(QA.Typography,{className:i.infoText},"This will fetch the BLAST results for the provided RID and run them through a multiple sequence alignment. The protein sequence from the selected transcript will be added as the query sequence in the MSA.")),Ct.default.createElement(dn,{submitDisabled:!C||!I,onSubmit:()=>{try{g&&I&&(c(void 0),wA({feature:g,view:a,newViewTitle:Wl(t,g),blastParams:{baseUrl:o,blastProgram:"blastp",blastDatabase:"nr",msaAlgorithm:u,selectedTranscript:g,proteinSequence:C,rid:I}}),e())}catch(E){console.error(E),c(E)}},onCancel:e}))}),fM=_3;var Qr=f(M()),Ar=f(O()),dM=f(wt());var T3=(0,dM.makeStyles)()({urlField:{minWidth:300}});function Np({handleClose:e,baseUrl:t}){let{classes:r}=T3(),[n,o]=(0,Qr.useState)(t);return Qr.default.createElement(Ar.Dialog,{open:!0,maxWidth:"lg",onClose:()=>{e()}},Qr.default.createElement(Ar.DialogTitle,null,"BLAST Settings"),Qr.default.createElement(Ar.DialogContent,null,Qr.default.createElement(ct,{autoFocus:!0,margin:"dense",label:"BLAST Base URL",fullWidth:!0,variant:"outlined",value:n,className:r.urlField,onChange:i=>{o(i.target.value)}}),Qr.default.createElement(Ar.Button,{variant:"contained",onClick:()=>{o(BA)}},"Reset")),Qr.default.createElement(Ar.DialogActions,null,Qr.default.createElement(Ar.Button,{variant:"contained",color:"secondary",onClick:()=>{e()}},"Cancel"),Qr.default.createElement(Ar.Button,{color:"primary",variant:"contained",onClick:()=>{e(n)}},"Save")))}var k3=(0,gM.makeStyles)()({settingsButton:{float:"right"}}),D3={automatic:tM,rid:fM,manual:lM};function Lp({handleClose:e,model:t,feature:r}){let[n,o]=(0,vr.useState)("automatic"),[i,a]=(0,mM.useLocalStorage)("msa-blastRootUrl",BA),[s,c]=(0,vr.useState)(!1),{classes:l}=k3(),A=D3[n];return vr.default.createElement(vr.default.Fragment,null,vr.default.createElement(pM.IconButton,{className:l.settingsButton,size:"small",onClick:()=>{c(!0)}},vr.default.createElement(G2,null)),vr.default.createElement(A,{model:t,feature:r,handleClose:e,baseUrl:i},vr.default.createElement(Dp,{lookupMethod:n,setLookupMethod:o})),s?vr.default.createElement(Np,{baseUrl:i,handleClose:u=>{u&&a(u),c(!1)}}):null)}var Et=f(M()),Is=f(Ne()),MA=f(de()),BM=f(O()),SM=f(H());var QM=f(wt());Qn();function Rp(e,t="",r=5e3){let n=[e];for(;n.length;){let o=n.pop();for(let[i,a]of Object.entries(o)){if(t.length>r)return wd(t);typeof a=="object"&&a!==null?n.push(a):i==="locationType"&&a==="FileHandleLocation"?t+=`${i}-BlobLocation`:i==="handleId"?t+=`blobId-fh-blob-${a}`:t+=`${i}-${a}`}}return`adp-${wd(t)}`}function hM(e={}){return e.type&&e.adapterId?`${e.type}-${e.adapterId}`:`${Rp(e)}`}var CM={};async function N3(e,t,r){let n=r?.type;if(!n)throw new Error(`could not determine adapter type from adapter config snapshot ${JSON.stringify(r)}`);let o=e.getAdapterType(n);if(!o)throw new Error(`unknown data adapter type ${n}`);let i=o.configSchema.create(r,{pluginManager:e}),a=Fp.bind(null,e,t),s=await o.getAdapterClass();return{dataAdapter:new s(i,a,e),sessionIds:new Set([t])}}async function Fp(e,t,r){let n=hM(r);CM[n]??=N3(e,t,r);let o=await CM[n];return o.sessionIds.add(t),o}async function EM(e,t){return(await Fp(e,"msa",t)).dataAdapter}async function IM({config:e,pluginManager:t}){return(await EM(t,e)).getMSAList()}async function xM({config:e,pluginManager:t,msaId:r}){return(await EM(t,e)).getMSA(r)}var yM=f(de());function wM({newViewTitle:e,view:t,feature:r,data:n,querySeqName:o}){(0,yM.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,treeAreaWidth:200,querySeqName:o,treeWidth:100,drawNodeBubbles:!1,labelsAlignRight:!0,showBranchLen:!1,colWidth:10,rowHeight:12,colorSchemeName:"percent_identity_dynamic",data:n,connectedViewId:t.id,connectedFeature:r.toJSON()})}var bM=f(Jo());function vA(e){return(0,bM.readConfObject)(e,["msa","datasets"])}var L3=(0,QM.makeStyles)()({selectedContainer:{marginTop:50}}),R3=(0,SM.observer)(function({model:e,feature:t,handleClose:r}){let n=(0,MA.getSession)(e),o=sr(e),{classes:i}=L3(),{pluginManager:a}=(0,MA.getEnv)(e),{assemblyNames:s}=o,[c,l]=(0,Et.useState)(),A=vA(n.jbrowse),[u,m]=(0,Et.useState)(A?.[0]?.datasetId),d=A?.find(k=>k.datasetId===u),{data:g,isLoading:C,error:y}=_o(d?`${d.datasetId}-msa-list`:null,()=>IM({config:d.adapter,pluginManager:a}),To),I=zr({feature:t,view:o,validIds:g}),{selectedId:E,selectedTranscript:b}=I,{data:x,isLoading:w,error:Q}=_o(E&&d&&g?`${d.datasetId}-${E}-msa`:null,()=>xM({msaId:E,config:d.adapter,pluginManager:a}),To),S=y??Q??I.error??c;return Et.default.createElement(Et.default.Fragment,null,Et.default.createElement(xr,{error:S},Et.default.createElement(ct,{select:!0,label:"Select MSA dataset",value:u,onChange:k=>{m(k.target.value)}},A?.map(k=>Et.default.createElement(BM.MenuItem,{key:k.datasetId,value:k.datasetId},k.name))),d?Et.default.createElement("div",{className:i.selectedContainer},!C&&w?Et.default.createElement(Is.LoadingEllipses,{variant:"h6",message:`Loading MSA for (${E})`}):null,C?Et.default.createElement(Is.LoadingEllipses,{variant:"h6",message:`Loading available MSAs for (${d.name})`}):null,g?Et.default.createElement("div",null,Et.default.createElement(Is.SanitizedHTML,{html:d.description}),Et.default.createElement(wr,{feature:t,...I})):null):null),Et.default.createElement(dn,{submitDisabled:!b||!x?.length,onSubmit:()=>{try{if(b&&x){let k=`${E}_${s[0]}`;wM({newViewTitle:Mo(b),view:o,querySeqName:k,feature:b,data:{msa:x.map(N=>`>${N.get("refName")}
+`),onProgress:b=>{e.setProgress(b)}}),E=JSON.stringify(f);return await yD({proteinSequence:c,blastDatabase:r,blastProgram:n,msaAlgorithm:o,msa:y.msa,tree:y.tree,treeMetadata:E,rid:u,geneId:a?.get("parentId"),transcriptId:a?.id(),transcriptName:a?.get("name")??a?.get("id"),geneName:a?.get("gene_name")??a?.get("parentId")}),{...y,treeMetadata:E}}function U9(e,t){let r={},n=e.taxid?t.get(e.taxid):void 0;return n?.sciname&&(r["Scientific name"]=n.sciname),n?.commonName&&(r["Common name"]=n.commonName),e.accession&&(r.Accession=e.accession),e.id&&(r.ID=e.id),e.title&&(r.Description=e.title),r}wg();var kD=p(f0());async function DD({location:e,name:t}){let r=i=>(0,kD.openLocation)({uri:i,locationType:"UriLocation"}),n=await r(`${e.uri}.idx`).readFile("utf8"),o=H9(n,t);if(o){let a=await new Oa({filehandle:r(e.uri),gziFilehandle:r(`${e.uri}.gzi`)}).read(o.length,o.offset);return new TextDecoder().decode(a).trim()}}var _D=e=>e.replace(/\.\d+$/,"");function H9(e,t){let r=_D(t);for(let n of e.split(`
+`)){let[o,i,a]=n.split("	");if(o&&_D(o)===r)return{offset:Number(i),length:Number(a)}}}var ND=p(Be());function RD({model:e}){let{hovered:t}=(0,ND.getSession)(e),{querySeqName:r,transcriptToMsaMap:n,connectedView:o,mafRegion:i}=e;if(!o?.initialized||!Ko(t))return;let{coord:a,refName:s}=t.hoverPosition;if(i)return s!==i.refName||!o.assemblyNames.includes(i.assemblyName)||a<i.start||a>=i.end?void 0:e.seqPosToVisibleCol(r,a-i.start);if(n){let c=n.g2p[a];if(c!==void 0)return e.seqPosToVisibleCol(r,c)}}ja();var V9="jbrowse-msaview-domain-cache",QA="domains",j9=1,M0;function LD(){return M0??=Vn(V9,j9,{upgrade(e){e.objectStoreNames.contains(QA)||e.createObjectStore(QA,{keyPath:"accession"})}}).catch(e=>{throw M0=void 0,e}),M0}async function FD(e){let r=(await LD()).transaction(QA,"readonly"),n=await Promise.all(e.map(o=>r.store.get(o)));return await r.done,n}async function PD(e){let r=(await LD()).transaction(QA,"readwrite");for(let n of e)await r.store.put(n);await r.done}function Do(e,t){return new RegExp(`<${t}>(.*?)</${t}>`,"s").exec(e)?.[1]}function Y9(e){let t={},r=/<GBQualifier>([\s\S]*?)<\/GBQualifier>/g,n;for(;(n=r.exec(e))!==null;){let o=Do(n[1],"GBQualifier_name"),i=Do(n[1],"GBQualifier_value");o&&i!==void 0&&t[o]===void 0&&(t[o]=i)}return t}function $9(e){let t=[],r=[],n=/<GBInterval>([\s\S]*?)<\/GBInterval>/g,o;for(;(o=n.exec(e))!==null;){let i=o[1],a=Do(i,"GBInterval_from"),s=Do(i,"GBInterval_to"),c=Do(i,"GBInterval_point");a&&s?(t.push(Number(a)),r.push(Number(s))):c&&(t.push(Number(c)),r.push(Number(c)))}return t.length>0?{start:Math.min(...t),end:Math.max(...r)}:void 0}var q9=2;function J9(e){let t=Do(e,"GBFeature_key"),r=Y9(e),n=r.db_xref,o=$9(e);if((t==="Region"||t==="Site")&&n?.startsWith("CDD:")&&o&&o.end-o.start+1>=q9){let i=n.replace("CDD:",""),a=t==="Region",s=r.note?.split(/[[(]/)[0]?.trim(),c=a?r.region_name??i:s||r.site_type||"site",l=a?i:`${i}:${c}`;return{signature:{entry:{name:c,description:r.note??c,accession:l}},locations:[o]}}}function W9(e){let t=new Map,r=/<GBSeq>([\s\S]*?)<\/GBSeq>/g,n;for(;(n=r.exec(e))!==null;){let o=n[1],i=[],a=/<GBFeature>([\s\S]*?)<\/GBFeature>/g,s;for(;(s=a.exec(o))!==null;){let c=J9(s[1]);c&&i.push(c)}for(let c of[Do(o,"GBSeq_accession-version"),Do(o,"GBSeq_primary-accession")])c&&t.set(c,i)}return t}async function OD(e){let t=[...new Set(e)].filter(Boolean),r=new Map,n=await FD(t),o=[];t.forEach((s,c)=>{let l=n[c];l?r.set(s,l.matches):o.push(s)});let i=[],a=100;for(let s=0;s<o.length;s+=a){let c=o.slice(s,s+a),l=await wn(TA({db:"protein",id:c.join(","),rettype:"gp",retmode:"xml"})),u=W9(l);for(let A of c){let m=u.get(A);m!==void 0&&(r.set(A,m),i.push({accession:A,matches:m}))}}return i.length>0&&await PD(i),r}async function GD(e){let t=e.data.treeMetadata;if(!t)throw new Error("No sequence metadata available to look up domains");let r=JSON.parse(t),n=Object.entries(r).map(([a,s])=>({rowName:a,accession:s.Accession})).filter(a=>!!a.accession);if(n.length===0)throw new Error("No NCBI accessions found in alignment rows");e.setProgress(`Fetching protein domains from NCBI for ${n.length} sequences...`);let o=await OD(n.map(a=>a.accession)),i={};for(let{rowName:a,accession:s}of n){let c=o.get(s);c&&c.length>0&&(i[a]={matches:c,xref:[{id:a}]})}if(Object.keys(i).length===0)throw new Error("No CDD domain annotations found for these proteins");e.setDomains(i)}ja();var z9="jbrowse-msaview-data",K9=1,zc="msa-data",_0;function k0(){return _0??=Vn(z9,K9,{upgrade(e){e.objectStoreNames.contains(zc)||e.createObjectStore(zc,{keyPath:"id"}).createIndex("timestamp","timestamp",{unique:!1})}}).catch(e=>{throw _0=void 0,e}),_0}function UD(){return`msa-${Date.now()}-${Math.random().toString(36).slice(2,11)}`}async function HD(e,t){try{let r=await k0(),n={id:e,msa:t.msa,tree:t.tree,treeMetadata:t.treeMetadata,timestamp:Date.now()};return await r.put(zc,n),!0}catch(r){return console.warn("Failed to store MSA data:",r),!1}}async function VD(e){try{let r=await(await k0()).get(zc,e);return r?{msa:r.msa,tree:r.tree,treeMetadata:r.treeMetadata}:void 0}catch(t){console.warn("Failed to retrieve MSA data:",t);return}}async function jD(e=10080*60*1e3){try{let t=await k0(),r=Date.now()-e,i=await t.transaction(zc,"readwrite").store.index("timestamp").openCursor(IDBKeyRange.upperBound(r)),a=0;for(;i;)await i.delete(),a++,i=await i.continue();return a}catch(t){return console.warn("Failed to cleanup old MSA data:",t),0}}function X9(e){let t=e;return t.type==="ProteinView"&&Array.isArray(t.structures)}function YD(e){return e.filter(X9)}function $D(e,t){if(t<0||t>=e.length)return;let r=0;for(let n=0;n<t;n++)e[n]!=="-"&&r++;if(e[t]!=="-")return r}function JD(e){let{dataStoreId:t,rows:r}=e;t&&r.length===0&&(async()=>{try{e.setLoadingStoredData(!0);let n=await VD(t);n&&(n.msa&&e.setMSA(n.msa),n.tree&&e.setTree(n.tree),n.treeMetadata&&e.setTreeMetadata(n.treeMetadata))}catch(n){console.error("Failed to load MSA data from IndexedDB:",n)}finally{e.setLoadingStoredData(!1)}})()}function WD(e){let{rows:t,dataStoreId:r,isStoringData:n}=e;if(t.length>0&&!r&&!n){if(e.msaFilehandle||e.treeFilehandle)return;let o=e.data.msa,i=e.data.tree;(o||i)&&(e.setIsStoringData(!0),(async()=>{try{let a=UD();await HD(a,{msa:o,tree:i,treeMetadata:e.data.treeMetadata})&&e.setDataStoreId(a)}catch(a){console.error("Failed to store MSA data to IndexedDB:",a)}finally{e.setIsStoringData(!1)}})())}}function zD(e){e.blastParams&&(async()=>{try{e.setProgress("Submitting query"),e.setError(void 0);let t=await MD({self:e});e.setData(t),e.setBlastParams(void 0)}catch(t){e.setError(t),console.error(t)}finally{e.setProgress("")}})()}function KD(e){let{rows:t,domainsRequested:r,interProAnnotations:n}=e,o=e.data.treeMetadata?.includes('"Accession"')??!1;t.length>0&&o&&!n&&!r&&(e.setDomainsRequested(!0),(async()=>{try{await GD(e)}catch(i){console.error("[msaview-domains] auto-load failed:",i)}finally{e.setProgress("")}})())}function XD(e){let{init:t}=e;if(t){let{msaUrl:r,msaIndexedLocation:n,msaName:o,querySeqName:i}=t;(async()=>{try{if(e.setError(void 0),r){let a=Nb(r);a&&(e.setUniprotId(a),e.setQuerySeqName("query"))}if(i&&e.setQuerySeqName(i),r)e.setMSAFilehandle({uri:r,locationType:"UriLocation"});else if(n&&o){let a=await DD({location:n,name:o});if(a)e.setMSA(a);else throw new Error(`No alignment named ${o} in ${n.uri}`)}e.setInit(void 0)}catch(a){e.setError(a),console.error(a)}})()}}function ZD(e){let t=!1;return()=>{let r=RD({model:e});r!==void 0?(e.setMousePos(r),t=!0):t&&(e.setMousePos(void 0),t=!1)}}function eN(e){let t=!1;return()=>{let{connectedViewId:r,transcriptToMsaMap:n,querySeqName:o}=e;if(!r||!n)return;let i=new Set;for(let s of YD((0,qD.getSession)(e).views))for(let c of s.structures){if(c.connectedViewId!==r)continue;let l=c.hoverGenomeHighlights;if(!l||l.length===0)continue;let{g2p:u}=n;for(let A of l)for(let m=A.start;m<A.end;m++){let f=u[m];if(f!==void 0){let g=e.seqPosToGlobalCol(o,f);i.add(g)}}}let a=Array.from(i).map(s=>e.globalColToVisibleCol(s)).filter(s=>s!==void 0);a.length>0?(e.setHighlightedColumns(a),t=!0):t&&(e.setHighlightedColumns(e.highlightColumns?.length?e.highlightColumns:void 0),t=!1)}}function tN(){jD().catch(e=>{console.error("Failed to cleanup old MSA data:",e)})}function MA({model:e,coord:t}){let{querySeqName:r,transcriptToMsaMap:n,mafRegion:o}=e,i=e.rows.find(s=>s[0]===r)?.[1];if(!i)return;let a=$D(i,t);if(a!==void 0){if(o){let s=o.start+a;return s<o.end?{refName:o.refName,start:s,end:s+1}:void 0}if(n){let{refName:s,p2g:c}=n,l=c[a],u=c[a+1];return l!==void 0&&u!==void 0?{refName:s,start:Math.min(l,u),end:Math.max(l,u)}:void 0}}}function D0(){return gt.types.compose(rN.BaseViewModel,gA(),gt.types.model("MsaView",{connectedViewId:gt.types.maybe(gt.types.string),connectedFeature:gt.types.frozen(),blastParams:gt.types.frozen(),querySeqName:"QUERY",uniprotId:gt.types.maybe(gt.types.string),zoomToBaseLevel:!1,init:gt.types.frozen(),dataStoreId:gt.types.maybe(gt.types.string),mafRegion:gt.types.frozen()})).volatile(()=>({rid:void 0,progress:"",error:void 0,loadingStoredData:!1,isStoringData:!1,domainsRequested:!1})).views(e=>({getRowByName(t){return e.rows.find(r=>r[0]===t)},getSequenceByRowName(t){return e.rows.find(r=>r[0]===t)?.[1]}})).views(e=>({get transcriptToMsaMap(){return e.connectedFeature?Fb(e.connectedFeature):void 0},get connectedView(){let{views:t}=(0,nN.getSession)(e);return t.find(r=>r.id===e.connectedViewId)}})).views(e=>({get connectedHoverHighlight(){let{mouseCol:t}=e;return t===void 0?void 0:MA({model:e,coord:t})},get connectedClickHighlight(){let{mouseClickCol:t}=e;return t===void 0?void 0:MA({model:e,coord:t})},get connectedHighlights(){return[this.connectedHoverHighlight,this.connectedClickHighlight].filter(t=>t!==void 0)}})).actions(e=>({setZoomToBaseLevel(t){e.zoomToBaseLevel=t},setError(t){e.error=t},setProgress(t){e.progress=t},setRid(t){e.rid=t},setBlastParams(t){e.blastParams=t},setInit(t){e.init=t},setQuerySeqName(t){e.querySeqName=t},setUniprotId(t){e.uniprotId=t},setDataStoreId(t){e.dataStoreId=t},setMafRegion(t){e.mafRegion=t},setLoadingStoredData(t){e.loadingStoredData=t},setIsStoringData(t){e.isStoringData=t},setDomainsRequested(t){e.domainsRequested=t},handleMsaClick(t){let{connectedView:r,zoomToBaseLevel:n}=e,o=MA({model:e,coord:t});!o||!r||(n?r.navTo(o):r.centerAt(o.start,o.refName))}})).actions(e=>{let t=e.setMouseClickPos.bind(e);return{setMouseClickPos(r,n){t(r,n),r!==void 0&&e.handleMsaClick(r)}}}).views(e=>({extraViewMenuItems(){return[{label:"Zoom to base level on click?",checked:e.zoomToBaseLevel,type:"checkbox",onClick:()=>{e.setZoomToBaseLevel(!e.zoomToBaseLevel)}}]}})).actions(e=>({afterCreate(){tN();for(let t of[JD,WD,zD,XD,KD])(0,gt.addDisposer)(e,(0,_A.autorun)(()=>{t(e)}));(0,gt.addDisposer)(e,(0,_A.autorun)(ZD(e))),(0,gt.addDisposer)(e,(0,_A.autorun)(eN(e)))}}))}function cs(e){return e.type==="MsaView"}var Z9=(0,R0.observer)(function({model:e}){let{hovered:t,views:r}=(0,oN.getSession)(e);return r.some(o=>cs(o)&&o.connectedViewId===e.id)&&Ko(t)?N0.default.createElement(eH,{model:e,hovered:t}):null}),eH=(0,R0.observer)(function({model:e,hovered:t}){let{classes:r}=xu(),{offsetPx:n}=e,{coord:o,refName:i}=t.hoverPosition,a=e.bpToPx({refName:i,coord:o-1}),s=e.bpToPx({refName:i,coord:o});if(a&&s){let c=Math.max(Math.abs(s.offsetPx-a.offsetPx),4),l=Math.min(a.offsetPx,s.offsetPx)-n;return N0.default.createElement("div",{className:r.highlight,style:{left:l,width:c}})}return null}),iN=Z9;var Kc=p(k()),aN=p(Be()),L0=p($());var tH=(0,L0.observer)(function({model:t}){let{views:r,hovered:n}=(0,aN.getSession)(t),o=r.filter(cs).find(c=>c.connectedViewId===t.id),i=o?.connectedClickHighlight,a=Ko(n)?void 0:o?.connectedHoverHighlight,s=[i,a].filter(c=>c!==void 0);return s.length?Kc.default.createElement(rH,{model:t,highlights:s}):null}),rH=(0,L0.observer)(function({model:e,highlights:t}){let{classes:r}=xu(),{offsetPx:n}=e;return Kc.default.createElement(Kc.default.Fragment,null,t.map((o,i)=>{let a=e.bpToPx({refName:o.refName,coord:o.start}),s=e.bpToPx({refName:o.refName,coord:o.end});if(a&&s){let c=Math.max(Math.abs(s.offsetPx-a.offsetPx),4),l=Math.min(a.offsetPx,s.offsetPx)-n;return Kc.default.createElement("div",{key:`${o.refName}-${o.start}-${o.end}-${i}`,className:r.highlight,style:{left:l,width:c}})}return null}))}),sN=tH;var nH=(0,cN.observer)(function({model:t}){return Xc.default.createElement(Xc.default.Fragment,null,Xc.default.createElement(sN,{model:t}),Xc.default.createElement(iN,{model:t}))}),lN=nH;function F0(e){e.addToExtensionPoint("LinearGenomeView-TracksContainerComponent",(t,{model:r})=>{let{views:n}=(0,fN.getSession)(r);return n.some(i=>cs(i)&&i.connectedViewId===r.id)?[...t,uN.default.createElement(lN,{key:"highlight_protein_viewer_msaview",model:r})]:t})}var yN=p(zm());var AN=p(Hi());function P0(e){let t=e.getAdapterType("BgzipFastaAdapter");return(0,AN.ConfigurationSchema)("BgzipFastaMsaAdapter",{msaRegex:{type:"string",defaultValue:"_"}},{baseConfiguration:t?.configSchema})}function O0(e){return e.addAdapterType(()=>new yN.AdapterType({name:"BgzipFastaMsaAdapter",configSchema:P0(e),adapterMetadata:{hiddenFromGUI:!0},getAdapterClass:()=>Promise.resolve().then(()=>(CN(),hN)).then(t=>t.default)}))}var rd=p(Be());Ee();var xN=p(O(),1),EN=Y((0,xN.jsx)("path",{d:"M19 13h-6v6h-2v-6H5v-2h6V5h2v6h6z"}),"Add");var qt=p(k()),tL=p(Ye()),rL=p(Be()),gs=p(V());var le=p(k()),aC=p(Ye()),Br=p(V()),aR=p($()),sR=p(Rt());var bN=p(Be());function IN({newViewTitle:e,view:t,feature:r,msaFilehandle:n,treeFilehandle:o,querySeqName:i,data:a}){(0,bN.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,connectedViewId:t.id,connectedFeature:r.toJSON(),msaFilehandle:n,treeFilehandle:o,querySeqName:i,data:a})}var G0=p(k()),wN=p(V());function oH({children:e,...t}){return G0.default.createElement("div",null,G0.default.createElement(wN.TextField,{...t},e))}var ht=oH;var U0=p(k()),SN=p(Ye()),BN=p(V()),vN=p(Rt()),iH=(0,vN.makeStyles)()({dialogContent:{width:"80em"}});function jr({error:e,children:t}){let{classes:r}=iH();return U0.default.createElement(BN.DialogContent,{className:r.dialogContent},e?U0.default.createElement(SN.ErrorMessage,{error:e}):null,t)}var DA=p(k()),Zc=p(V());function Jn({onSubmit:e,onCancel:t,submitDisabled:r,submitLabel:n="Submit",cancelLabel:o="Cancel"}){return DA.default.createElement(Zc.DialogActions,null,DA.default.createElement(Zc.Button,{color:"primary",variant:"contained",disabled:r,onClick:()=>{e()}},n),DA.default.createElement(Zc.Button,{color:"secondary",variant:"contained",onClick:()=>{t()}},o))}var Yr=p(k()),ls=p(V()),MN=p(Rt());var TN=p(k()),QN=p(Rt());var aH=(0,QN.makeStyles)()({textAreaFont:{fontFamily:"Courier New"}});function H0({value:e}){let{classes:t}=aH();return TN.default.createElement(ht,{variant:"outlined",multiline:!0,minRows:5,maxRows:10,fullWidth:!0,value:e,slotProps:{input:{readOnly:!0,classes:{input:t.textAreaFont}}}})}var sH=(0,MN.makeStyles)()({flex:{display:"flex"},minWidth:{minWidth:300},centered:{alignContent:"center",marginLeft:20}});function $r({feature:e,options:t,selectedId:r,selectedTranscript:n,setSelectedId:o,proteinSequence:i,validIds:a}){let{classes:s}=sH(),[c,l]=(0,Yr.useState)(!1);return Yr.default.createElement(Yr.default.Fragment,null,Yr.default.createElement("div",{className:s.flex},Yr.default.createElement(ls.TextField,{variant:"outlined",label:`Choose isoform of ${Bi(e)}`,select:!0,className:s.minWidth,value:r,onChange:u=>{o(u.target.value)}},t.map(u=>{let A=a?a.some(g=>ss(u,g)):!0,{len:m,mod:f}=hA(u);return Yr.default.createElement(ls.MenuItem,{value:Si(u),key:u.id(),disabled:!A},yA(u)," (",m," aa)"," ",f?" (possible fragment)":"",a?A?" (has data)":" (no data)":"")})),Yr.default.createElement("div",{className:s.centered},Yr.default.createElement(ls.Button,{variant:"contained",color:"primary",onClick:()=>{l(!c)}},c?"Hide sequence":"Show sequence"))),c?Yr.default.createElement(H0,{value:i?`>${yA(n)}
+${i}`:"Loading..."}):null)}var JA=p(k());var NA=p(Be());A2();function _N({cds:e,sequence:t,codonTable:r}){let n=e[0]?.phase??0,o=f2(e,t),i=n>0?"&":"";for(let a=n;a<o.length;a+=3)i+=r[o.slice(a,a+3)]||"&";return i}var cH=[{id:1,name:"Standard",ncbieaa:"FFLLSSSSYY**CC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"---M------**--*----M---------------M----------------------------"},{id:2,name:"Vertebrate Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNKKSS**VVVVAAAADDEEGGGG",sncbieaa:"----------**--------------------MMMM----------**---M------------"},{id:3,name:"Yeast Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWTTTTPPPPHHQQRRRRIIMMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**----------------------MM---------------M------------"},{id:4,name:"Mold Mitochondrial; Protozoan Mitochondrial; Coelenterate Mitochondrial; Mycoplasma; Spiroplasma",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--MM------**-------M------------MMMM---------------M------------"},{id:5,name:"Invertebrate Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNKKSSSSVVVVAAAADDEEGGGG",sncbieaa:"---M------**--------------------MMMM---------------M------------"},{id:6,name:"Ciliate Nuclear; Dasycladacean Nuclear; Hexamita Nuclear",ncbieaa:"FFLLSSSSYYQQCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--------------*--------------------M----------------------------"},{id:9,name:"Echinoderm Mitochondrial; Flatworm Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNNKSSSSVVVVAAAADDEEGGGG",sncbieaa:"----------**-----------------------M---------------M------------"},{id:10,name:"Euplotid Nuclear",ncbieaa:"FFLLSSSSYY**CCCWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**-----------------------M----------------------------"},{id:11,name:"Bacterial, Archaeal and Plant Plastid",ncbieaa:"FFLLSSSSYY**CC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"---M------**--*----M------------MMMM---------------M------------"},{id:12,name:"Alternative Yeast Nuclear",ncbieaa:"FFLLSSSSYY**CC*WLLLSPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**--*----M---------------M----------------------------"},{id:13,name:"Ascidian Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNKKSSGGVVVVAAAADDEEGGGG",sncbieaa:"---M------**----------------------MM---------------M------------"},{id:14,name:"Alternative Flatworm Mitochondrial",ncbieaa:"FFLLSSSSYYY*CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNNKSSSSVVVVAAAADDEEGGGG",sncbieaa:"-----------*-----------------------M----------------------------"},{id:15,name:"Blepharisma Macronuclear",ncbieaa:"FFLLSSSSYY*QCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------*---*--------------------M----------------------------"},{id:16,name:"Chlorophycean Mitochondrial",ncbieaa:"FFLLSSSSYY*LCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------*---*--------------------M----------------------------"},{id:21,name:"Trematode Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIMMTTTTNNNKSSSSVVVVAAAADDEEGGGG",sncbieaa:"----------**-----------------------M---------------M------------"},{id:22,name:"Scenedesmus obliquus Mitochondrial",ncbieaa:"FFLLSS*SYY*LCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"------*---*---*--------------------M----------------------------"},{id:23,name:"Thraustochytrium Mitochondrial",ncbieaa:"FF*LSSSSYY**CC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--*-------**--*-----------------M--M---------------M------------"},{id:24,name:"Rhabdopleuridae Mitochondrial",ncbieaa:"FFLLSSSSYY**CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSSKVVVVAAAADDEEGGGG",sncbieaa:"---M------**-------M---------------M---------------M------------"},{id:25,name:"Candidate Division SR1 and Gracilibacteria",ncbieaa:"FFLLSSSSYY**CCGWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"---M------**-----------------------M---------------M------------"},{id:26,name:"Pachysolen tannophilus Nuclear",ncbieaa:"FFLLSSSSYY**CC*WLLLAPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**--*----M---------------M----------------------------"},{id:27,name:"Karyorelict Nuclear",ncbieaa:"FFLLSSSSYYQQCCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--------------*--------------------M----------------------------"},{id:28,name:"Condylostoma Nuclear",ncbieaa:"FFLLSSSSYYQQCCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**--*--------------------M----------------------------"},{id:29,name:"Mesodinium Nuclear",ncbieaa:"FFLLSSSSYYYYCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--------------*--------------------M----------------------------"},{id:30,name:"Peritrich Nuclear",ncbieaa:"FFLLSSSSYYEECC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"--------------*--------------------M----------------------------"},{id:31,name:"Blastocrithidia Nuclear",ncbieaa:"FFLLSSSSYYEECCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"----------**-----------------------M----------------------------"},{id:32,name:"Balanophoraceae Plastid",ncbieaa:"FFLLSSSSYY*WCC*WLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSRRVVVVAAAADDEEGGGG",sncbieaa:"---M------*---*----M------------MMMM---------------M------------"},{id:33,name:"Cephalodiscidae Mitochondrial",ncbieaa:"FFLLSSSSYYY*CCWWLLLLPPPPHHQQRRRRIIIMTTTTNNKKSSSKVVVVAAAADDEEGGGG",sncbieaa:"---M-------*-------M---------------M---------------M------------"}],lH="TTTTTTTTTTTTTTTTCCCCCCCCCCCCCCCCAAAAAAAAAAAAAAAAGGGGGGGGGGGGGGGG",uH="TTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGGTTTTCCCCAAAAGGGG",fH="TCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAGTCAG",AH=Array.from({length:64},(e,t)=>lH[t]+uH[t]+fH[t]),kN=new Map(cH.map(e=>[e.id,e]));function dH(e){let t={};for(let[r,n]of Object.entries(e)){let o=i=>{let a=r.charAt(i);return[a.toUpperCase(),a.toLowerCase()]};for(let i of o(0))for(let a of o(1))for(let s of o(2))t[i+a+s]=n}return t}function mH(e){let t=kN.get(e);!t&&e!==1&&console.warn(`Unknown genetic code (transl_table=${e}); using standard code`);let{id:r,name:n,ncbieaa:o,sncbieaa:i}=t??kN.get(1),a={},s=[];for(let[c,l]of AH.entries())a[l]=o[c],i[c]==="M"&&s.push(l);return{id:r,name:n,codonTable:dH(a),starts:s}}var DN=new Map;function NN(e=1){let t=DN.get(e);return t||(t=mH(e),DN.set(e,t)),t}function V0(e){let t=Array.isArray(e)?e[0]:e,r=Number(t);return Number.isInteger(r)&&r>0?r:void 0}function pH({cds:e,sequence:t,geneticCodeId:r}){let{codonTable:n}=NN(r);return _N({cds:e,sequence:t,codonTable:n})}function gH(e,t){return e.map(r=>({...r,start:t-r.end,end:t-r.start})).toSorted((r,n)=>r.start-n.start)}function RN({feature:e,seq:t}){let{subfeatures:r,start:n,strand:o}=e.toJSON(),i=(0,NA.dedupe)(r?.toSorted((c,l)=>c.start-l.start).map(c=>({...c,start:c.start-n,end:c.end-n})).filter(c=>c.type==="CDS")??[],c=>`${c.start}-${c.end}`),a=e.get("subfeatures")?.find(c=>c.get("type")?.toLowerCase()==="cds"),s=V0(e.get("transl_table"))??V0(a?.get("transl_table"));return pH({cds:o===-1?gH(i,t.length):i,sequence:o===-1?(0,NA.revcom)(t):t,geneticCodeId:s})}var nR=p(Be());var ot=p(k(),1),iC=p(ON(),1);var Ct=p(k(),1);var No={};bt(No,{ERROR_REVALIDATE_EVENT:()=>BH,FOCUS_EVENT:()=>GN,MUTATE_EVENT:()=>HN,RECONNECT_EVENT:()=>UN});var GN=0,UN=1,HN=2,BH=3;var VN=Object.prototype.hasOwnProperty;function RA(e,t){var r,n;if(e===t)return!0;if(e&&t&&(r=e.constructor)===t.constructor){if(r===Date)return e.getTime()===t.getTime();if(r===RegExp)return e.toString()===t.toString();if(r===Array){if((n=e.length)===t.length)for(;n--&&RA(e[n],t[n]););return n===-1}if(!r||typeof e=="object"){n=0;for(r in e)if(VN.call(e,r)&&++n&&!VN.call(t,r)||!(r in t)||!RA(e[r],t[r]))return!1;return Object.keys(t).length===n}}return e!==e&&t!==t}var qr=new WeakMap,Jr=()=>{},et=Jr(),fs=Object,Z=e=>e===et,sr=e=>typeof e=="function",Wr=(e,t)=>({...e,...t}),UA=e=>sr(e.then),Y0={},LA={},X0="undefined",As=typeof window!=X0,PA=typeof document!=X0,YN=As&&"Deno"in window,$N=()=>As&&typeof window.requestAnimationFrame!=X0,HA=(e,t)=>{let r=qr.get(e);return[()=>!Z(t)&&e.get(t)||Y0,n=>{if(!Z(t)){let o=e.get(t);t in LA||(LA[t]=o),r[5](t,Wr(o,n),o||Y0)}},r[6],()=>!Z(t)&&t in LA?LA[t]:!Z(t)&&e.get(t)||Y0]},J0=!0,vH=()=>J0,[W0,z0]=As&&window.addEventListener?[window.addEventListener.bind(window),window.removeEventListener.bind(window)]:[Jr,Jr],TH=()=>{let e=PA&&document.visibilityState;return Z(e)||e!=="hidden"},QH=e=>(PA&&document.addEventListener("visibilitychange",e),W0("focus",e),()=>{PA&&document.removeEventListener("visibilitychange",e),z0("focus",e)}),MH=e=>{let t=()=>{J0=!0,e()},r=()=>{J0=!1};return W0("online",t),W0("offline",r),()=>{z0("online",t),z0("offline",r)}},qN={isOnline:vH,isVisible:TH},JN={initFocus:QH,initReconnect:MH},VA=!Ct.default.useId,Ro=!As||YN,Z0=e=>$N()?window.requestAnimationFrame(e):setTimeout(e,1),ds=Ro?Ct.useEffect:Ct.useLayoutEffect,$0=typeof navigator<"u"&&navigator.connection,K0=!Ro&&$0&&(["slow-2g","2g"].includes($0.effectiveType)||$0.saveData),FA=new WeakMap,_H=e=>fs.prototype.toString.call(e),q0=(e,t)=>e===`[object ${t}]`,kH=0,OA=e=>{let t=typeof e,r=_H(e),n=q0(r,"Date"),o=q0(r,"RegExp"),i=q0(r,"Object"),a,s;if(fs(e)===e&&!n&&!o){if(a=FA.get(e),a)return a;if(a=++kH+"~",FA.set(e,a),Array.isArray(e)){for(a="@",s=0;s<e.length;s++)a+=OA(e[s])+",";FA.set(e,a)}if(i){a="#";let c=fs.keys(e).sort();for(;!Z(s=c.pop());)Z(e[s])||(a+=s+":"+OA(e[s])+",");FA.set(e,a)}}else a=n?e.toJSON():t=="symbol"?e.toString():t=="string"?JSON.stringify(e):""+e;return a},tl=e=>{if(sr(e))try{e=e()}catch{e=""}let t=e;return e=typeof e=="string"?e:(Array.isArray(e)?e.length:e)?OA(e):"",[e,t]},DH=0,el=()=>++DH;async function jA(...e){let[t,r,n,o]=e,i=Wr({populateCache:!0,throwOnError:!0},typeof o=="boolean"?{revalidate:o}:o||{}),a=i.populateCache,s=i.rollbackOnError,c=i.optimisticData,l=m=>typeof s=="function"?s(m):s!==!1,u=i.throwOnError;if(sr(r)){let m=r,f=[],g=t.keys();for(let y of g)!/^\$(inf|sub)\$/.test(y)&&m(t.get(y)._k)&&f.push(y);return Promise.all(f.map(A))}return A(r);async function A(m){let[f]=tl(m);if(!f)return;let[g,y]=HA(t,f),[E,b,x,B]=qr.get(t),I=()=>{let _=E[f];return(sr(i.revalidate)?i.revalidate(g().data,m):i.revalidate!==!1)&&(delete x[f],delete B[f],_&&_[0])?_[0](2).then(()=>g().data):g().data};if(e.length<3)return I();let w=n,S,v=!1,D=el();b[f]=[D,0];let N=!Z(c),L=g(),P=L.data,h=L._c,Q=Z(h)?P:h;if(N&&(c=sr(c)?c(Q,P):c,y({data:c,_c:Q})),sr(w))try{w=w(Q)}catch(_){S=_,v=!0}if(w&&UA(w))if(w=await w.catch(_=>{S=_,v=!0}),D!==b[f][0]){if(v)throw S;return w}else v&&N&&l(S)&&(a=!0,y({data:Q,_c:et}));if(a&&!v)if(sr(a)){let _=a(w,Q);y({data:_,error:et,_c:et})}else y({data:w,error:et,_c:et});if(b[f][1]=el(),Promise.resolve(I()).then(()=>{y({_c:et})}),v){if(u)throw S;return}return w}}var jN=(e,t)=>{for(let r in e)e[r][0]&&e[r][0](t)},eC=(e,t)=>{if(!qr.has(e)){let r=Wr(JN,t),n=Object.create(null),o=jA.bind(et,e),i=Jr,a=Object.create(null),s=(u,A)=>{let m=a[u]||[];return a[u]=m,m.push(A),()=>{let f=m.indexOf(A);f>=0&&(m[f]=m[m.length-1],m.pop())}},c=(u,A,m)=>{e.set(u,A);let f=a[u];if(f)for(let g of f)g(A,m)},l=()=>{if(!qr.has(e)&&(qr.set(e,[n,Object.create(null),Object.create(null),Object.create(null),o,c,s]),!Ro)){let u=r.initFocus(setTimeout.bind(et,jN.bind(et,n,0))),A=r.initReconnect(setTimeout.bind(et,jN.bind(et,n,1)));i=()=>{u&&u(),A&&A(),qr.delete(e)}}};return l(),[e,o,l,i]}return[e,qr.get(e)[4]]},NH=(e,t,r,n,o)=>{let i=r.errorRetryCount,a=o.retryCount,s=~~((Math.random()+.5)*(1<<(a<8?a:8)))*r.errorRetryInterval;!Z(i)&&a>i||setTimeout(n,s,o)},WN=RA,[YA,zN]=eC(new Map),$A=Wr({onLoadingSlow:Jr,onSuccess:Jr,onError:Jr,onErrorRetry:NH,onDiscarded:Jr,revalidateOnFocus:!0,revalidateOnReconnect:!0,revalidateIfStale:!0,shouldRetryOnError:!0,errorRetryInterval:K0?1e4:5e3,focusThrottleInterval:5*1e3,dedupingInterval:2*1e3,loadingTimeout:K0?5e3:3e3,compare:WN,isPaused:()=>!1,cache:YA,mutate:zN,fallback:{}},qN),tC=(e,t)=>{let r=Wr(e,t);if(t){let{use:n,fallback:o}=e,{use:i,fallback:a}=t;n&&i&&(r.use=n.concat(i)),o&&a&&(r.fallback=Wr(o,a))}return r},GA=(0,Ct.createContext)({}),rC=e=>{let{value:t}=e,r=(0,Ct.useContext)(GA),n=sr(t),o=(0,Ct.useMemo)(()=>n?t(r):t,[n,r,t]),i=(0,Ct.useMemo)(()=>n?o:tC(r,o),[n,r,o]),a=o&&o.provider,s=(0,Ct.useRef)(et);a&&!s.current&&(s.current=eC(a(i.cache||YA),o));let c=s.current;return c&&(i.cache=c[0],i.mutate=c[1]),ds(()=>{if(c)return c[2]&&c[2](),c[3]},[]),(0,Ct.createElement)(GA.Provider,Wr(e,{value:i}))};var KN="$inf$";var ms=p(k(),1);var XN=As&&window.__SWR_DEVTOOLS_USE__,RH=XN?window.__SWR_DEVTOOLS_USE__:[],LH=()=>{XN&&(window.__SWR_DEVTOOLS_REACT__=ms.default)},FH=e=>sr(e[1])?[e[0],e[1],e[2]||{}]:[e[0],null,(e[1]===null?e[2]:e[1])||{}],PH=()=>{let e=(0,ms.useContext)(GA);return(0,ms.useMemo)(()=>Wr($A,e),[e])};var OH=e=>(t,r,n)=>e(t,r&&((...i)=>{let[a]=tl(t),[,,,s]=qr.get(YA);if(a.startsWith(KN))return r(...i);let c=s[a];return Z(c)?r(...i):(delete s[a],c)}),n),GH=RH.concat(OH),ZN=e=>function(...r){let n=PH(),[o,i,a]=FH(r),s=tC(n,a),c=e,{use:l}=s,u=(l||[]).concat(GH);for(let A=u.length;A--;)c=u[A](c);return c(o,i||s.fetcher||null,s)},eR=(e,t,r)=>{let n=t[e]||(t[e]=[]);return n.push(r),()=>{let o=n.indexOf(r);o>=0&&(n[o]=n[n.length-1],n.pop())}};LH();var UH=()=>{},pAe=UH();var nC=ot.default.use||(e=>{switch(e.status){case"pending":throw e;case"fulfilled":return e.value;case"rejected":throw e.reason;default:throw e.status="pending",e.then(t=>{e.status="fulfilled",e.value=t},t=>{e.status="rejected",e.reason=t}),e}}),oC={dedupe:!0},qA=Promise.resolve(et);qA.status="fulfilled";qA.value=et;var HH=()=>Jr,VH=(e,t,r)=>{let{cache:n,compare:o,suspense:i,fallbackData:a,revalidateOnMount:s,revalidateIfStale:c,refreshInterval:l,refreshWhenHidden:u,refreshWhenOffline:A,keepPreviousData:m,strictServerPrefetchWarning:f}=r,[g,y,E,b]=qr.get(n),[x,B]=tl(e),I=(0,ot.useRef)(!1),w=(0,ot.useRef)(!1),S=(0,ot.useRef)(x),v=(0,ot.useRef)(t),D=(0,ot.useRef)(r),N=()=>D.current,L=()=>N().isVisible()&&N().isOnline(),[P,h,Q,_]=HA(n,x),G=(0,ot.useRef)({}).current,q=Z(a)?Z(r.fallback)?et:r.fallback[x]:a,oe=(fe,ie)=>{for(let ke in G){let Se=ke;if(Se==="data"){if(!o(fe[Se],ie[Se])&&(!Z(fe[Se])||!o(ki,ie[Se])))return!1}else if(ie[Se]!==fe[Se])return!1}return!0},tt=!I.current,_i=(0,ot.useMemo)(()=>{let fe=P(),ie=_(),ke=ge=>{let Je=Wr(ge);return delete Je._k,(()=>{if(!x||!t||N().isPaused())return!1;if(tt&&!Z(s))return s;let Qn=Z(q)?Je.data:q;return i?Z(Qn)||c:Z(Qn)||c})()?{isValidating:!0,isLoading:!0,...Je}:Je},Se=ke(fe),Jt=fe===ie?Se:ke(ie),Qt=Se;return[()=>{let ge=ke(P());return oe(ge,Qt)?(Qt.data=ge.data,Qt.isLoading=ge.isLoading,Qt.isValidating=ge.isValidating,Qt.error=ge.error,Qt):(Qt=ge,ge)},()=>Jt]},[n,x]),lr=(0,iC.useSyncExternalStore)((0,ot.useCallback)(fe=>Q(x,(ie,ke)=>{oe(ke,ie)||fe()}),[n,x]),_i[0],_i[1]),ue=g[x]&&g[x].length>0,Mr=lr.data,ur=Z(Mr)?q&&UA(q)?nC(q):q:Mr,Xr=lr.error,vn=(0,ot.useRef)(ur),ki=m?Z(Mr)?Z(vn.current)?ur:vn.current:Mr:ur,Tn=x&&Z(ur),zn=(0,ot.useRef)(null);!Ro&&(0,iC.useSyncExternalStore)(HH,()=>(zn.current=!1,zn),()=>(zn.current=!0,zn));let ad=zn.current;f&&ad&&!i&&Tn&&console.warn(`Missing pre-initiated data for serialized key "${x}" during server-side rendering. Data fetching should be initiated on the server and provided to SWR via fallback data. You can set "strictServerPrefetchWarning: false" to disable this warning.`);let hs=!x||!t||N().isPaused()||ue&&!Z(Xr)?!1:tt&&!Z(s)?s:i?Z(ur)?!1:c:Z(ur)||c,Ie=tt&&hs,al=Z(lr.isValidating)?Ie:lr.isValidating,_e=Z(lr.isLoading)?Ie:lr.isLoading,Kn=(0,ot.useCallback)(async fe=>{let ie=v.current;if(!x||!ie||w.current||N().isPaused())return!1;let ke,Se,Jt=!0,Qt=fe||{},ge=!E[x]||!Qt.dedupe,Je=()=>VA?!w.current&&x===S.current&&I.current:x===S.current,Wt={isValidating:!1,isLoading:!1},Qn=()=>{h(Wt)},Ni=()=>{let yt=E[x];yt&&yt[1]===Se&&delete E[x]},Ri={isValidating:!0};Z(P().data)&&(Ri.isLoading=!0);try{if(ge&&(h(Ri),r.loadingTimeout&&Z(P().data)&&setTimeout(()=>{Jt&&Je()&&N().onLoadingSlow(x,r)},r.loadingTimeout),E[x]=[ie(B),el()]),[ke,Se]=E[x],ke=await ke,ge&&setTimeout(Ni,r.dedupingInterval),!E[x]||E[x][1]!==Se)return ge&&Je()&&N().onDiscarded(x),!1;Wt.error=et;let yt=y[x];if(!Z(yt)&&(Se<=yt[0]||Se<=yt[1]||yt[1]===0))return Qn(),ge&&Je()&&N().onDiscarded(x),!1;let xt=P().data;Wt.data=o(xt,ke)?xt:ke,ge&&Je()&&N().onSuccess(ke,x,r)}catch(yt){Ni();let xt=N(),{shouldRetryOnError:Xn}=xt;xt.isPaused()||(Wt.error=yt,ge&&Je()&&(xt.onError(yt,x,xt),(Xn===!0||sr(Xn)&&Xn(yt))&&(!N().revalidateOnFocus||!N().revalidateOnReconnect||L())&&xt.onErrorRetry(yt,x,xt,Li=>{let Fi=g[x];Fi&&Fi[0]&&Fi[0](No.ERROR_REVALIDATE_EVENT,Li)},{retryCount:(Qt.retryCount||0)+1,dedupe:!0})))}return Jt=!1,Qn(),!0},[x,n]),we=(0,ot.useCallback)((...fe)=>jA(n,S.current,...fe),[]);if(ds(()=>{v.current=t,D.current=r,Z(Mr)||(vn.current=Mr)}),ds(()=>{if(!x)return;let fe=Kn.bind(et,oC),ie=0;N().revalidateOnFocus&&(ie=Date.now()+N().focusThrottleInterval);let Se=eR(x,g,(Jt,Qt={})=>{if(Jt==No.FOCUS_EVENT){let ge=Date.now();N().revalidateOnFocus&&ge>ie&&L()&&(ie=ge+N().focusThrottleInterval,fe())}else if(Jt==No.RECONNECT_EVENT)N().revalidateOnReconnect&&L()&&fe();else{if(Jt==No.MUTATE_EVENT)return Kn();if(Jt==No.ERROR_REVALIDATE_EVENT)return Kn(Qt)}});return w.current=!1,S.current=x,I.current=!0,h({_k:B}),hs&&(E[x]||(Z(ur)||Ro?fe():Z0(fe))),()=>{w.current=!0,Se()}},[x]),ds(()=>{let fe;function ie(){let Se=sr(l)?l(P().data):l;Se&&fe!==-1&&(fe=setTimeout(ke,Se))}function ke(){!P().error&&(u||N().isVisible())&&(A||N().isOnline())?Kn(oC).then(ie):ie()}return ie(),()=>{fe&&(clearTimeout(fe),fe=-1)}},[l,u,A,x]),(0,ot.useDebugValue)(ki),i){if(!VA&&Ro&&Tn)throw new Error("Fallback data is required when using Suspense in SSR.");Tn&&(v.current=t,D.current=r,w.current=!1);let fe=b[x],ie=!Z(fe)&&Tn?we(fe):qA;if(nC(ie),!Z(Xr)&&Tn)throw Xr;let ke=Tn?Kn(oC):qA;!Z(ki)&&Tn&&(ke.status="fulfilled",ke.value=!0),nC(ke)}return{mutate:we,get data(){return G.data=!0,ki},get error(){return G.error=!0,Xr},get isValidating(){return G.isValidating=!0,al},get isLoading(){return G.isLoading=!0,_e}}},gAe=fs.defineProperty(rC,"defaultValue",{value:$A}),vi=ZN(VH);var tR=p(Hi());async function rR({start:e,end:t,refName:r,session:n,assemblyName:o}){let{assemblyManager:i,rpcManager:a}=n,s=await i.waitForAssembly(o);if(!s)throw new Error("assembly not found");let c="getSequence";return(await a.call(c,"CoreGetFeatures",{adapterConfig:(0,tR.getConf)(s,["sequence","adapter"]),sessionId:c,regions:[{start:e,end:t,refName:s.getCanonicalRefName(r),assemblyName:o}]}))[0]?.get("seq")??""}var Ti={revalidateOnFocus:!1,revalidateOnReconnect:!1,revalidateIfStale:!1,refreshWhenHidden:!1,refreshWhenOffline:!1,shouldRetryOnError:!1};async function jH({feature:e,assemblyName:t,view:r}){let n=(0,nR.getSession)(r),{start:o,end:i,refName:a}=e.toJSON();return{seq:await rR({start:o,end:i,refName:a,assemblyName:t,session:n})}}function oR({view:e,feature:t}){let r=e?.assemblyNames?.[0],n=t&&r?{feature:t,assemblyName:r,view:e}:void 0,{data:o,error:i}=vi(n?[n.feature.id(),n.assemblyName,"feature-sequence"]:null,()=>jH(n),Ti);return{sequence:o,error:i}}function iR({view:e,feature:t}){let{sequence:r,error:n}=oR({view:e,feature:t});return{proteinSequence:r&&t?RN({seq:r.seq,feature:t}):"",sequence:r,error:n}}function YH(e,t,r){if(!r?.length)return e;let n=a=>r.some(s=>ss(a,s)),o=t.find(a=>Si(a)===e);if(o&&n(o))return e;let i=t.find(n);return i?Si(i):e}function Sn({feature:e,view:t,validIds:r}){let n=(0,JA.useMemo)(()=>EA(e),[e]),[o,i]=(0,JA.useState)(()=>Si(n[0])),a=YH(o,n,r),s=n.find(u=>Si(u)===a),{proteinSequence:c,error:l}=iR({view:t,feature:s});return{options:n,selectedId:a,setSelectedId:i,selectedTranscript:s,proteinSequence:c,error:l,validIds:r}}var $H=(0,sR.makeStyles)()({textAreaFont:{fontFamily:"Courier New"},inputContainer:{marginBottom:30},fileContainer:{maxWidth:500},msaInput:{marginBottom:20},queryNameInput:{marginTop:20},warningAlert:{marginTop:10}}),qH=(0,aR.observer)(function({model:t,feature:r,handleClose:n}){let o=Sr(t),{classes:i}=$H(),[a,s]=(0,le.useState)(),[c,l]=(0,le.useState)("file"),[u,A]=(0,le.useState)(""),[m,f]=(0,le.useState)(""),[g,y]=(0,le.useState)(),[E,b]=(0,le.useState)(),[x,B]=(0,le.useState)(""),I=Sn({feature:r,view:o}),{selectedTranscript:w,error:S}=I;return le.default.createElement(le.default.Fragment,null,le.default.createElement(jr,{error:a??S},le.default.createElement(Br.FormControl,{component:"fieldset"},le.default.createElement(Br.RadioGroup,{row:!0,value:c,onChange:D=>{l(D.target.value)}},le.default.createElement(Br.FormControlLabel,{value:"file",control:le.default.createElement(Br.Radio,null),label:"Open files"}),le.default.createElement(Br.FormControlLabel,{value:"text",control:le.default.createElement(Br.Radio,null),label:"Paste text"}))),le.default.createElement("div",{className:i.inputContainer},c==="file"?le.default.createElement("div",{className:i.fileContainer},le.default.createElement(aC.FileSelector,{name:"MSA File .aln (Clustal), .fa/.mfa (aligned FASTA), .stock (Stockholm), etc)",inline:!0,location:g,setLocation:y}),le.default.createElement(aC.FileSelector,{name:"Tree file .nh (Newick) or .asn (NCBI COBALT ASN.1)",inline:!0,location:E,setLocation:b})):le.default.createElement(le.default.Fragment,null,le.default.createElement(ht,{variant:"outlined",name:"MSA",multiline:!0,minRows:5,className:i.msaInput,maxRows:10,fullWidth:!0,placeholder:"Paste MSA here",value:u,onChange:D=>{A(D.target.value)}}),le.default.createElement(ht,{variant:"outlined",name:"Tree",multiline:!0,minRows:5,maxRows:10,fullWidth:!0,placeholder:"Paste newick tree (optional)",value:m,onChange:D=>{f(D.target.value)}}))),le.default.createElement($r,{feature:r,...I}),le.default.createElement(ht,{variant:"outlined",name:"MSA row name",fullWidth:!0,required:!0,className:i.queryNameInput,placeholder:"Row name in MSA that corresponds to the selected transcript",helperText:"Required: Specify the name of the row in your MSA that should be aligned with the selected transcript",value:x,onChange:D=>{B(D.target.value)}}),x.trim()?null:le.default.createElement(Br.Alert,{severity:"warning",className:i.warningAlert},"Without specifying the MSA row name, clicking on the MSA will not navigate to the corresponding genome position, and hovering highlights will not work.")),le.default.createElement(Jn,{submitDisabled:!w||c==="file"&&!g||c==="text"&&!u.trim(),onSubmit:()=>{try{w&&(s(void 0),IN({newViewTitle:Bi(w),view:o,feature:w,querySeqName:x.trim(),...c==="file"?{msaFilehandle:g,treeFilehandle:E}:{data:{msa:u,tree:m}}}),n())}catch(D){console.error(D),s(D)}},onCancel:n}))}),cR=qH;var Kr=p(k());Ee();var lR=p(O(),1),uR=Y((0,lR.jsx)("path",{d:"M19.14 12.94c.04-.3.06-.61.06-.94 0-.32-.02-.64-.07-.94l2.03-1.58c.18-.14.23-.41.12-.61l-1.92-3.32c-.12-.22-.37-.29-.59-.22l-2.39.96c-.5-.38-1.03-.7-1.62-.94l-.36-2.54c-.04-.24-.24-.41-.48-.41h-3.84c-.24 0-.43.17-.47.41l-.36 2.54c-.59.24-1.13.57-1.62.94l-2.39-.96c-.22-.08-.47 0-.59.22L2.74 8.87c-.12.21-.08.47.12.61l2.03 1.58c-.05.3-.09.63-.09.94s.02.64.07.94l-2.03 1.58c-.18.14-.23.41-.12.61l1.92 3.32c.12.22.37.29.59.22l2.39-.96c.5.38 1.03.7 1.62.94l.36 2.54c.05.24.24.41.48.41h3.84c.24 0 .44-.17.47-.41l.36-2.54c.59-.24 1.13-.56 1.62-.94l2.39.96c.22.08.47 0 .59-.22l1.92-3.32c.12-.22.07-.47-.12-.61zM12 15.6c-1.98 0-3.6-1.62-3.6-3.6s1.62-3.6 3.6-3.6 3.6 1.62 3.6 3.6-1.62 3.6-3.6 3.6"}),"Settings");var GR=p(V()),UR=p(Rt());var xe=p(k());r0();var cr=p(V()),IR=p($()),wR=p(Rt());var ft=p(k()),pR=p(Ye());Ee();var fR=p(O(),1),AR=Y((0,fR.jsx)("path",{d:"M6 19c0 1.1.9 2 2 2h8c1.1 0 2-.9 2-2V7H6zM19 4h-3.5l-1-1h-5l-1 1H5v2h14z"}),"Delete");var Bt=p(V()),gR=p($()),hR=p(Rt());var sC=p(Be());function WA({newViewTitle:e,view:t,feature:r,blastParams:n}){(0,sC.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,connectedViewId:t.id,connectedFeature:r.toJSON(),drawNodeBubbles:!0,colWidth:10,rowHeight:12,blastParams:n})}function dR({newViewTitle:e,view:t,cached:r,connectedFeature:n}){(0,sC.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,connectedViewId:t.id,connectedFeature:n,drawNodeBubbles:!0,colWidth:10,rowHeight:12,data:{msa:r.msa,tree:r.tree,treeMetadata:r.treeMetadata}})}function zA(e){let{data:t,error:r,isLoading:n,mutate:o}=vi(`cached-blast-${e.join(",")}`,async()=>(await xD()).filter(c=>c.geneId&&e.includes(c.geneId)),Ti);return{results:t??[],error:r,isLoading:n,handleDelete:async s=>{await ED(s),await o(c=>c?.filter(l=>l.id!==s)??[],!1)},handleClearAll:async()=>{await bD(),await o([],!1)}}}var JH=(0,hR.makeStyles)()({header:{display:"flex",justifyContent:"space-between",alignItems:"center",marginBottom:8},resultList:{maxHeight:300,overflow:"auto"}});function mR(e){let t=[e.geneName,e.transcriptName!==e.geneName?e.transcriptName:void 0].filter(r=>!!r);return t.length>0?t.join(" - "):e.geneId??e.transcriptId??"Unknown"}var WH=(0,gR.observer)(function({model:e,handleClose:t,feature:r}){let{classes:n}=JH(),o=Sr(e),[i,a]=(0,ft.useState)(),s=(0,ft.useMemo)(()=>IA(r),[r]),{results:c,error:l,isLoading:u,handleDelete:A,handleClearAll:m}=zA(s),f=y=>{let{transcriptId:E}=y,b=E?EA(r).find(x=>ss(x,E)):void 0;dR({view:o,cached:y,newViewTitle:`BLAST - ${mR(y)}`,connectedFeature:b?.toJSON()}),t()},g=l??i;return g?ft.default.createElement(pR.ErrorMessage,{error:g}):u?ft.default.createElement(Bt.Typography,null,"Loading cached results..."):c.length===0?ft.default.createElement(Bt.Typography,{color:"textSecondary"},"No cached BLAST results found for this gene. Run a BLAST query to cache results."):ft.default.createElement("div",null,ft.default.createElement("div",{className:n.header},ft.default.createElement(Bt.Typography,{variant:"subtitle1"},"Cached BLAST Results (",c.length,")"),ft.default.createElement(Bt.Button,{size:"small",color:"error",onClick:async()=>{try{a(void 0),await m()}catch(y){a(y)}}},"Clear All")),ft.default.createElement(Bt.List,{dense:!0,className:n.resultList},c.map(y=>ft.default.createElement(Bt.ListItem,{key:y.id,disablePadding:!0,secondaryAction:ft.default.createElement(Bt.IconButton,{edge:"end",size:"small",onClick:async E=>{E.stopPropagation();try{a(void 0),await A(y.id)}catch(b){a(b)}}},ft.default.createElement(AR,{fontSize:"small"}))},ft.default.createElement(Bt.ListItemButton,{onClick:()=>{f(y)}},ft.default.createElement(Bt.ListItemText,{primary:`${mR(y)} - ${y.blastDatabase}/${y.blastProgram} (${y.msaAlgorithm})`,secondary:`${new Date(y.timestamp).toLocaleString()} - Seq: ${y.proteinSequence.slice(0,30)}...`}))))))}),CR=WH;var cC=p(k()),bR=p(V());var KA="https://blast.ncbi.nlm.nih.gov/Blast.cgi",yR=["clustalo","muscle","kalign","mafft"],xR=["nr","nr_cluster_seq"],ER=["blastp","quick-blastp"];function rl({value:e,onChange:t,className:r}){return cC.default.createElement(ht,{variant:"outlined",label:"MSA Algorithm",className:r,select:!0,value:e,onChange:n=>{t(n.target.value)}},yR.map(n=>cC.default.createElement(bR.MenuItem,{value:n,key:n},n)))}var zH=(0,wR.makeStyles)()({selectField:{width:150},databaseFieldContainer:{display:"flex"},clusterSeqMessage:{marginLeft:4,alignContent:"center"},cachedResultsAccordion:{marginTop:20},infoText:{marginTop:20}}),KH=(0,IR.observer)(function({handleClose:e,feature:t,model:r,children:n,baseUrl:o}){let{classes:i}=zH(),a=Sr(r),[s,c]=(0,xe.useState)(),[l,u]=(0,xe.useState)("nr"),[A,m]=(0,xe.useState)("clustalo"),[f,g]=(0,xe.useState)("quick-blastp"),y=(0,xe.useMemo)(()=>IA(t),[t]),{results:E,error:b}=zA(y),x=Sn({feature:t,view:a}),{selectedTranscript:B,proteinSequence:I}=x,w=x.error??s??b;return xe.default.createElement(xe.default.Fragment,null,xe.default.createElement(jr,{error:w},n,xe.default.createElement(ht,{variant:"outlined",label:"BLAST database",className:i.selectField,select:!0,value:l,onChange:S=>{let v=S.target.value;u(v),v==="nr_cluster_seq"&&g("blastp")}},xR.map(S=>xe.default.createElement(cr.MenuItem,{value:S,key:S},S))),xe.default.createElement(rl,{className:i.selectField,value:A,onChange:m}),xe.default.createElement("div",{className:i.databaseFieldContainer},xe.default.createElement(ht,{variant:"outlined",label:"BLAST program",disabled:l==="nr_cluster_seq",className:i.selectField,select:!0,value:f,onChange:S=>{g(S.target.value)}},ER.map(S=>xe.default.createElement(cr.MenuItem,{value:S,key:S},S))),l==="nr_cluster_seq"?xe.default.createElement(cr.Typography,{variant:"subtitle2",className:i.clusterSeqMessage},"Can only use blastp on nr_cluster_seq"):null),xe.default.createElement($r,{feature:t,...x}),xe.default.createElement(cr.Typography,{className:i.infoText},"This panel will automatically submit a query to NCBI. Using blastp can take 10+ minutes to run, quick-blastp is generally a lot faster but is not available for the clustered database. After completion, all the hits will be run through a multiple sequence alignment. Note: we are not able to currently run NCBI COBALT automatically on the BLAST results, even though that is the method NCBI uses on their website. If you need a COBALT alignment, please use the manual approach of submitting BLAST yourself and downloading the resulting files"),E.length>0?xe.default.createElement(cr.Accordion,{className:i.cachedResultsAccordion},xe.default.createElement(cr.AccordionSummary,{expandIcon:xe.default.createElement(Zf,null)},xe.default.createElement(cr.Typography,null,"Previous BLAST Results")),xe.default.createElement(cr.AccordionDetails,null,xe.default.createElement(CR,{model:r,handleClose:e,feature:t}))):null),xe.default.createElement(Jn,{submitDisabled:!I,onSubmit:()=>{try{B&&(c(void 0),WA({feature:B,view:a,newViewTitle:xA(t,B),blastParams:{baseUrl:o,blastProgram:f,blastDatabase:l,msaAlgorithm:A,selectedTranscript:B,proteinSequence:I}}),e())}catch(S){console.error(S),c(S)}},onCancel:e}))}),SR=KH;var Bn=p(k()),MR=p(Be()),ps=p(V()),_R=p($()),kR=p(Rt());XA();var XH=(0,kR.makeStyles)()({ncbiLink:{wordBreak:"break-all",margin:30,maxWidth:600},infoText:{marginTop:20}}),ZH=(0,_R.observer)(function({handleClose:e,feature:t,model:r,children:n,baseUrl:o}){let{classes:i}=XH(),a=Sr(r),s=Sn({feature:t,view:a}),{proteinSequence:c,error:l}=s,u=bA(c),A=`${o}?PAGE_TYPE=BlastSearch&PAGE=Proteins&PROGRAM=blastp&QUERY=${u}`,m=`${o}?PAGE_TYPE=BlastSearch&PAGE=Proteins&PROGRAM=blastp&QUERY=${(0,MR.shorten2)(u,10)}`;return Bn.default.createElement(Bn.default.Fragment,null,Bn.default.createElement(jr,{error:l},n,Bn.default.createElement($r,{feature:t,...s}),c?Bn.default.createElement("div",{className:i.ncbiLink},"Link to NCBI BLAST: ",Bn.default.createElement(Qi,{href:A},m)):null,Bn.default.createElement(ps.Typography,{className:i.infoText},`Click the link above and run your BLAST query, and once you have results, click "Multiple Alignment" at the top of the results page to be redirected to COBALT, NCBI's multiple sequence aligner. Once COBALT completes, you can download an MSA (.aln file) and optionally a Newick tree (.nh) and paste the results into JBrowse`)),Bn.default.createElement(ps.DialogActions,null,Bn.default.createElement(ps.Button,{color:"primary",variant:"contained",onClick:()=>{e()}},"Close")))}),DR=ZH;var Wn=p(k()),vr=p(V());function uC({lookupMethod:e,setLookupMethod:t}){return Wn.default.createElement(vr.FormControl,{component:"fieldset"},Wn.default.createElement(vr.RadioGroup,{row:!0,value:e,onChange:r=>{t(r.target.value)}},Wn.default.createElement(vr.FormControlLabel,{value:"automatic",control:Wn.default.createElement(vr.Radio,null),label:"Automatic"}),Wn.default.createElement(vr.FormControlLabel,{value:"rid",control:Wn.default.createElement(vr.Radio,null),label:"Load from RID"}),Wn.default.createElement(vr.FormControlLabel,{value:"manual",control:Wn.default.createElement(vr.Radio,null),label:"Manual"})))}var vt=p(k()),ZA=p(V()),NR=p($()),RR=p(Rt());XA();var eV=(0,RR.makeStyles)()({marginBottom:{marginBottom:16},ridField:{width:150},infoText:{marginTop:20}}),tV=(0,NR.observer)(function({handleClose:e,feature:t,model:r,children:n,baseUrl:o}){let{classes:i}=eV(),a=Sr(r),[s,c]=(0,vt.useState)(),[l,u]=(0,vt.useState)(""),[A,m]=(0,vt.useState)("clustalo"),f=Sn({feature:t,view:a}),{selectedTranscript:g,proteinSequence:y}=f,E=f.error??s,b=l.trim();return vt.default.createElement(vt.default.Fragment,null,vt.default.createElement(jr,{error:E},n,vt.default.createElement(ZA.Typography,{variant:"body2",className:i.marginBottom},"Enter the RID (Request ID) from a previously submitted NCBI BLAST query. You can find the RID in the BLAST results page URL or at the top of the results page. RIDs are typically valid for 24-36 hours after submission."),vt.default.createElement(ht,{variant:"outlined",label:"BLAST RID",placeholder:"e.g., ABC12345",fullWidth:!0,className:i.marginBottom,value:l,onChange:x=>{u(x.target.value)}}),b?vt.default.createElement(ZA.Typography,{variant:"body2",className:i.marginBottom},vt.default.createElement(Qi,{href:`${o}?CMD=Get&RID=${b}`},"View BLAST results on NCBI")):null,vt.default.createElement(rl,{className:i.ridField,value:A,onChange:m}),vt.default.createElement($r,{feature:t,...f}),vt.default.createElement(ZA.Typography,{className:i.infoText},"This will fetch the BLAST results for the provided RID and run them through a multiple sequence alignment. The protein sequence from the selected transcript will be added as the query sequence in the MSA.")),vt.default.createElement(Jn,{submitDisabled:!y||!b,onSubmit:()=>{try{g&&b&&(c(void 0),WA({feature:g,view:a,newViewTitle:xA(t,g),blastParams:{baseUrl:o,blastProgram:"blastp",blastDatabase:"nr",msaAlgorithm:A,selectedTranscript:g,proteinSequence:y,rid:b}}),e())}catch(x){console.error(x),c(x)}},onCancel:e}))}),LR=tV;var zr=p(k()),Tr=p(V()),FR=p(Rt());var rV=(0,FR.makeStyles)()({urlField:{minWidth:300}});function fC({handleClose:e,baseUrl:t}){let{classes:r}=rV(),[n,o]=(0,zr.useState)(t);return zr.default.createElement(Tr.Dialog,{open:!0,maxWidth:"lg",onClose:()=>{e()}},zr.default.createElement(Tr.DialogTitle,null,"BLAST Settings"),zr.default.createElement(Tr.DialogContent,null,zr.default.createElement(ht,{autoFocus:!0,margin:"dense",label:"BLAST Base URL",fullWidth:!0,variant:"outlined",value:n,className:r.urlField,onChange:i=>{o(i.target.value)}}),zr.default.createElement(Tr.Button,{variant:"contained",onClick:()=>{o(KA)}},"Reset")),zr.default.createElement(Tr.DialogActions,null,zr.default.createElement(Tr.Button,{variant:"contained",color:"secondary",onClick:()=>{e()}},"Cancel"),zr.default.createElement(Tr.Button,{color:"primary",variant:"contained",onClick:()=>{e(n)}},"Save")))}var PR=p(k());function nV(e,t){try{let r=globalThis.localStorage.getItem(e);return r===null?t:JSON.parse(r)}catch(r){return console.error(r),t}}function OR(e,t){let[r,n]=(0,PR.useState)(()=>nV(e,t));return[r,i=>{n(i);try{globalThis.localStorage.setItem(e,JSON.stringify(i))}catch(a){console.error(a)}}]}var oV=(0,UR.makeStyles)()({settingsButton:{float:"right"}}),iV={automatic:SR,rid:LR,manual:DR};function AC({handleClose:e,model:t,feature:r}){let[n,o]=(0,Kr.useState)("automatic"),[i,a]=OR("msa-blastRootUrl",KA),[s,c]=(0,Kr.useState)(!1),{classes:l}=oV(),u=iV[n];return Kr.default.createElement(Kr.default.Fragment,null,Kr.default.createElement(GR.IconButton,{className:l.settingsButton,size:"small",onClick:()=>{c(!0)}},Kr.default.createElement(uR,null)),Kr.default.createElement(u,{model:t,feature:r,handleClose:e,baseUrl:i},Kr.default.createElement(uC,{lookupMethod:n,setLookupMethod:o})),s?Kr.default.createElement(fC,{baseUrl:i,handleClose:A=>{A&&a(A),c(!1)}}):null)}var Tt=p(k()),nl=p(Ye()),td=p(Be()),zR=p(V()),KR=p($());var XR=p(Rt());Ao();function dC(e,t="",r=5e3){let n=[e];for(;n.length;){let o=n.pop();for(let[i,a]of Object.entries(o)){if(t.length>r)return th(t);typeof a=="object"&&a!==null?n.push(a):i==="locationType"&&a==="FileHandleLocation"?t+=`${i}-BlobLocation`:i==="handleId"?t+=`blobId-fh-blob-${a}`:t+=`${i}-${a}`}}return`adp-${th(t)}`}function HR(e={}){return e.type&&e.adapterId?`${e.type}-${e.adapterId}`:`${dC(e)}`}var VR={};async function aV(e,t,r){let n=r?.type;if(!n)throw new Error(`could not determine adapter type from adapter config snapshot ${JSON.stringify(r)}`);let o=e.getAdapterType(n);if(!o)throw new Error(`unknown data adapter type ${n}`);let i=o.configSchema.create(r,{pluginManager:e}),a=mC.bind(null,e,t),s=await o.getAdapterClass();return{dataAdapter:new s(i,a,e),sessionIds:new Set([t])}}async function mC(e,t,r){let n=HR(r);VR[n]??=aV(e,t,r);let o=await VR[n];return o.sessionIds.add(t),o}async function jR(e,t){return(await mC(e,"msa",t)).dataAdapter}async function YR({config:e,pluginManager:t}){return(await jR(t,e)).getMSAList()}async function $R({config:e,pluginManager:t,msaId:r}){return(await jR(t,e)).getMSA(r)}var qR=p(Be());function JR({newViewTitle:e,view:t,feature:r,data:n,querySeqName:o}){(0,qR.getSession)(t).addView("MsaView",{type:"MsaView",displayName:e,treeAreaWidth:200,querySeqName:o,treeWidth:100,drawNodeBubbles:!1,labelsAlignRight:!0,showBranchLen:!1,colWidth:10,rowHeight:12,colorSchemeName:"percent_identity_dynamic",data:n,connectedViewId:t.id,connectedFeature:r.toJSON()})}var WR=p(Hi());function ed(e){return(0,WR.readConfObject)(e,["msa","datasets"])}var sV=(0,XR.makeStyles)()({selectedContainer:{marginTop:50}}),cV=(0,KR.observer)(function({model:e,feature:t,handleClose:r}){let n=(0,td.getSession)(e),o=Sr(e),{classes:i}=sV(),{pluginManager:a}=(0,td.getEnv)(e),{assemblyNames:s}=o,[c,l]=(0,Tt.useState)(),u=ed(n.jbrowse),[A,m]=(0,Tt.useState)(u?.[0]?.datasetId),f=u?.find(D=>D.datasetId===A),{data:g,isLoading:y,error:E}=vi(f?`${f.datasetId}-msa-list`:null,()=>YR({config:f.adapter,pluginManager:a}),Ti),b=Sn({feature:t,view:o,validIds:g}),{selectedId:x,selectedTranscript:B}=b,{data:I,isLoading:w,error:S}=vi(x&&f&&g?`${f.datasetId}-${x}-msa`:null,()=>$R({msaId:x,config:f.adapter,pluginManager:a}),Ti),v=E??S??b.error??c;return Tt.default.createElement(Tt.default.Fragment,null,Tt.default.createElement(jr,{error:v},Tt.default.createElement(ht,{select:!0,label:"Select MSA dataset",value:A,onChange:D=>{m(D.target.value)}},u?.map(D=>Tt.default.createElement(zR.MenuItem,{key:D.datasetId,value:D.datasetId},D.name))),f?Tt.default.createElement("div",{className:i.selectedContainer},!y&&w?Tt.default.createElement(nl.LoadingEllipses,{variant:"h6",message:`Loading MSA for (${x})`}):null,y?Tt.default.createElement(nl.LoadingEllipses,{variant:"h6",message:`Loading available MSAs for (${f.name})`}):null,g?Tt.default.createElement("div",null,Tt.default.createElement(nl.SanitizedHTML,{html:f.description}),Tt.default.createElement($r,{feature:t,...b})):null):null),Tt.default.createElement(Jn,{submitDisabled:!B||!I?.length,onSubmit:()=>{try{if(B&&I){let D=`${x}_${s[0]}`;JR({newViewTitle:Bi(B),view:o,querySeqName:D,feature:B,data:{msa:I.map(N=>`>${N.get("refName")}
 ${N.get("seq")}`).join(`
-`)}}),r()}}catch(k){l(k)}},onCancel:r}))}),vM=R3;var MM=f(M());function xs({children:e,value:t,index:r,...n}){return MM.default.createElement("div",{role:"tabpanel",hidden:t!==r,...n},t===r?e:null)}function Pp({handleClose:e,feature:t,model:r}){let n=(0,TM.getSession)(r),i=!!vA(n.jbrowse)?.length,[a,s]=(0,Lt.useState)("ncbi_blast");return Lt.default.createElement(_M.Dialog,{maxWidth:"xl",title:"Launch MSA view",open:!0,onClose:e},Lt.default.createElement(ta.Tabs,{value:a,onChange:(c,l)=>{s(l)}},Lt.default.createElement(ta.Tab,{label:"NCBI BLAST query",value:"ncbi_blast"}),i?Lt.default.createElement(ta.Tab,{label:"Pre-loaded MSA datasets",value:"preloaded_msa"}):null,Lt.default.createElement(ta.Tab,{label:"Manual upload",value:"manual_msa"})),Lt.default.createElement(xs,{value:a,index:"ncbi_blast"},Lt.default.createElement(Lp,{handleClose:e,feature:t,model:r})),i?Lt.default.createElement(xs,{value:a,index:"preloaded_msa"},Lt.default.createElement(vM,{model:r,feature:t,handleClose:e})):null,Lt.default.createElement(xs,{value:a,index:"manual_msa"},Lt.default.createElement(P2,{model:r,feature:t,handleClose:e})))}function F3(e){return e.name==="LinearBasicDisplay"}function P3(e){return e.views(t=>{let r=t.contextMenuItems;return{contextMenuItems(){let n=(0,_A.getContainingTrack)(t),o=(0,_A.getSession)(n),i=t.contextMenuInfo,a=i&&t.isGeneLike;return[...r(),...a?[{label:"Launch MSA view",icon:t2,onClick:()=>{t.fetchFullFeature(i.item.featureId,i.displayedRegionIndex).then(s=>{s?o.queueDialog(c=>[Pp,{model:n,handleClose:c,feature:s}]):o.notify("Could not load feature for MSA view","warning")}).catch(s=>{o.notifyError(`${s}`,s)})}}]:[]]}}})}function Op(e){e.addToExtensionPoint("Core-extendPluggableElement",t=>(F3(t)&&(t.stateModel=P3(t.stateModel)),t))}function Gp(e){e.addToExtensionPoint("LaunchView-MsaView",t=>{let{session:r,data:n,msaFileLocation:o,msaIndexedLocation:i,msaName:a,treeFileLocation:s,querySeqName:c,...l}=t;if(!n&&!o&&!i)throw new Error("No MSA data or file location provided when launching MSA view");return r.addView("MsaView",{type:"MsaView",...l,data:n,...s?{treeFilehandle:{...s,locationType:"UriLocation"}}:{},init:{msaUrl:o?.uri,msaIndexedLocation:i,msaName:a,querySeqName:c}}),t})}var zM=f(M()),WM=f(DM());var V3=(0,zM.lazy)(()=>Promise.resolve().then(()=>(YM(),VM)));function qp(e){e.addViewType(()=>new WM.default({name:"MsaView",stateModel:np(),ReactComponent:V3}))}var $M="2.7.0";var DA=class extends KM.default{constructor(){super(...arguments);this.name="MsaViewPlugin";this.version=$M;this.rootConfigurationSchema=r=>({msa:(0,Jp.ConfigurationSchema)("MSA",{datasets:Vp.types.maybe(Vp.types.array((0,Jp.ConfigurationSchema)("MSAEntry",{datasetId:{type:"string",defaultValue:""},description:{type:"string",defaultValue:""},name:{type:"string",defaultValue:""},adapter:r.pluggableConfigSchemaType("adapter")})))})})}install(r){qp(r),Op(r),Gp(r),sp(r),lp(r)}configure(r){(0,XM.isAbstractMenuManager)(r.rootModel)&&r.rootModel.appendToSubMenu(["Add"],{label:"Multiple sequence alignment view",icon:Eg,onClick:n=>{n.addView("MsaView",{})}})}};return I_(Y3);})();
+`)}}),r()}}catch(D){l(D)}},onCancel:r}))}),ZR=cV;var eL=p(k());function ol({children:e,value:t,index:r,...n}){return eL.default.createElement("div",{role:"tabpanel",hidden:t!==r,...n},t===r?e:null)}function pC({handleClose:e,feature:t,model:r}){let n=(0,rL.getSession)(r),i=!!ed(n.jbrowse)?.length,[a,s]=(0,qt.useState)("ncbi_blast");return qt.default.createElement(tL.Dialog,{maxWidth:"xl",title:"Launch MSA view",open:!0,onClose:e},qt.default.createElement(gs.Tabs,{value:a,onChange:(c,l)=>{s(l)}},qt.default.createElement(gs.Tab,{label:"NCBI BLAST query",value:"ncbi_blast"}),i?qt.default.createElement(gs.Tab,{label:"Pre-loaded MSA datasets",value:"preloaded_msa"}):null,qt.default.createElement(gs.Tab,{label:"Manual upload",value:"manual_msa"})),qt.default.createElement(ol,{value:a,index:"ncbi_blast"},qt.default.createElement(AC,{handleClose:e,feature:t,model:r})),i?qt.default.createElement(ol,{value:a,index:"preloaded_msa"},qt.default.createElement(ZR,{model:r,feature:t,handleClose:e})):null,qt.default.createElement(ol,{value:a,index:"manual_msa"},qt.default.createElement(cR,{model:r,feature:t,handleClose:e})))}function lV(e){return e.name==="LinearBasicDisplay"}var uV=new Set(["gene","mRNA","transcript"]);function fV(e){return e.views(t=>{let r=t.contextMenuItems;return{contextMenuItems(){let n=(0,rd.getContainingTrack)(t),o=(0,rd.getSession)(n),i=u=>{o.queueDialog(A=>[pC,{model:n,handleClose:A,feature:u}])},a=t.contextMenuInfo,s=t.fetchFullFeature,c=t.contextMenuFeature,l=a&&s&&t.isGeneLike?()=>{s(a.item.featureId,a.displayedRegionIndex).then(u=>{u?i(u):o.notify("Could not load feature for MSA view","warning")}).catch(u=>{o.notifyError(`${u}`,u)})}:c&&uV.has(String(c.get("type")))?()=>{i(c)}:void 0;return[...r(),...l?[{label:"Launch MSA view",icon:EN,onClick:l}]:[]]}}})}function gC(e){e.addToExtensionPoint("Core-extendPluggableElement",t=>(lV(t)&&(t.stateModel=fV(t.stateModel)),t))}function hC(e){e.addToExtensionPoint("LaunchView-MsaView",t=>{let{session:r,data:n,msaFileLocation:o,msaIndexedLocation:i,msaName:a,treeFileLocation:s,querySeqName:c,...l}=t;if(!n&&!o&&!i)throw new Error("No MSA data or file location provided when launching MSA view");return r.addView("MsaView",{type:"MsaView",...l,data:n,...s?{treeFilehandle:{...s,locationType:"UriLocation"}}:{},init:{msaUrl:o?.uri,msaIndexedLocation:i,msaName:a,querySeqName:c}}),t})}var yL=p(k()),xL=p(oL());var yV=(0,yL.lazy)(()=>Promise.resolve().then(()=>(CL(),hL)));function EC(e){e.addViewType(()=>new xL.default({name:"MsaView",stateModel:D0(),ReactComponent:yV}))}var EL="2.7.2";var id=class extends bL.default{constructor(){super(...arguments);this.name="MsaViewPlugin";this.version=EL;this.rootConfigurationSchema=r=>({msa:(0,bC.ConfigurationSchema)("MSA",{datasets:IC.types.maybe(IC.types.array((0,bC.ConfigurationSchema)("MSAEntry",{datasetId:{type:"string",defaultValue:""},description:{type:"string",defaultValue:""},name:{type:"string",defaultValue:""},adapter:r.pluggableConfigSchemaType("adapter")})))})})}install(r){EC(r),gC(r),hC(r),F0(r),O0(r)}configure(r){(0,IL.isAbstractMenuManager)(r.rootModel)&&r.rootModel.appendToSubMenu(["Add"],{label:"Multiple sequence alignment view",icon:_b,onClick:n=>{n.addView("MsaView",{})}})}};return YL(xV);})();
 /*! Bundled license information:
 
+react-is/cjs/react-is.production.js:
+  (**
+   * @license React
+   * react-is.production.js
+   *
+   * Copyright (c) Meta Platforms, Inc. and affiliates.
+   *
+   * This source code is licensed under the MIT license found in the
+   * LICENSE file in the root directory of this source tree.
+   *)
+
 react-is/cjs/react-is.production.min.js:
   (** @license React v16.13.1
    * react-is.production.min.js
@@ -86,6 +106,24 @@ react-is/cjs/react-is.production.min.js:
    * LICENSE file in the root directory of this source tree.
    *)
 
+@mui/styled-engine/index.mjs:
+  (**
+   * @mui/styled-engine v9.1.1
+   *
+   * @license MIT
+   * This source code is licensed under the MIT license found in the
+   * LICENSE file in the root directory of this source tree.
+   *)
+
+@mui/system/index.mjs:
+  (**
+   * @mui/system v9.2.0
+   *
+   * @license MIT
+   * This source code is licensed under the MIT license found in the
+   * LICENSE file in the root directory of this source tree.
+   *)
+
 escape-html/index.js:
   (*!
    * escape-html