jbrowse-plugin-graphgenomeviewer 8.3.4 → 8.3.6

package/dist/chunks/WalkTabixSyntenyAdapter-I3MGWUQ5.js.map

@@ -1,7 +0,0 @@
-{
-  "version": 3,
-  "sources": ["../../src/WalkTabixSyntenyAdapter/walkLanes.ts", "../../src/WalkTabixSyntenyAdapter/WalkTabixSyntenyAdapter.ts"],
-  "sourcesContent": ["import { weightedLcs } from '@gmod/gbz-base/lcs'\nimport { pairAlignments, pairCigar } from '@gmod/gbz-base/pairAlignment'\nimport { panSNContig } from '@jbrowse/bandage-core/pansn'\n\nimport { matchFeature } from '../synteny/matchFeature.ts'\n\nimport type { PairChain, PairEdit } from '@gmod/gbz-base/pairAlignment'\nimport type { WalkFragment, WalkNode } from '@jbrowse/graph-walks'\n\n// The longest bubble with equal bases on both sides that is written as\n// mismatches; a longer one stays an insertion and a deletion\nconst BALANCED_BUBBLE_MAX_BP = 50\n\n/**\n * A chain's edits with each short balanced bubble as `X`. The walks carry no\n * bases, so two walks differ wherever they leave a shared node, and a SNP is\n * one base inserted and one deleted until it is read as the mismatch it is.\n */\nexport function bubblesAsMismatches(edits: PairEdit[]) {\n  const out: PairEdit[] = []\n  for (let i = 0; i < edits.length; i++) {\n    const [op, len] = edits[i]!\n    const [nextOp, nextLen] = edits[i + 1] ?? []\n    if (\n      len === nextLen &&\n      len <= BALANCED_BUBBLE_MAX_BP &&\n      ((op === 'I' && nextOp === 'D') || (op === 'D' && nextOp === 'I'))\n    ) {\n      out.push(['X', len])\n      i++\n    } else {\n      out.push([op, len])\n    }\n  }\n  return out\n}\n\n// A walk's steps as the handles gbz-base reads, 2 * id + reversed\nfunction handlesOf(fragment: WalkFragment) {\n  return Array.from(fragment.ids, (id, i) => 2 * id + fragment.rev[i]!)\n}\n\nfunction nodeLength(nodes: Map<number, WalkNode>, id: number) {\n  const node = nodes.get(id)\n  return node === undefined ? 0 : node.end - node.start\n}\n\n/**\n * Aligns one walk fragment to another on the nodes both visit, from node\n * lengths alone: the fragments' steps as the handles gbz-base's chainer reads,\n * and a stand-in sequence of each node's length.\n */\nexport function walkAligner(nodes: Map<number, WalkNode>) {\n  const standIn = new Map<number, string>()\n  const sequenceOf = (id: number) => {\n    const length = nodeLength(nodes, id)\n    let sequence = standIn.get(length)\n    if (sequence === undefined) {\n      sequence = 'N'.repeat(length)\n      standIn.set(length, sequence)\n    }\n    return sequence\n  }\n  const handles = new Map<WalkFragment, number[]>()\n  const cachedHandles = (fragment: WalkFragment) => {\n    let steps = handles.get(fragment)\n    if (steps === undefined) {\n      steps = handlesOf(fragment)\n      handles.set(fragment, steps)\n    }\n    return steps\n  }\n  return (query: WalkFragment, target: WalkFragment) =>\n    pairAlignments({\n      query: cachedHandles(query),\n      target: cachedHandles(target),\n      sequenceOf,\n      bases: false,\n    })\n}\n\n// The fewest bases on shared nodes a record against the reference keeps,\n// gbz-base's floor for a pair record\nconst MIN_MATCH_BP = 100\n\nfunction appendEdit(edits: PairEdit[], op: PairEdit[0], len: number) {\n  const last = edits.at(-1)\n  if (len > 0) {\n    if (last?.[0] === op) {\n      last[1] += len\n    } else {\n      edits.push([op, len])\n    }\n  }\n}\n\n/**\n * Aligns a haplotype's walk fragment to the reference's as gbz-base aligns a\n * walk to its reference path: the heaviest common subsequence of their steps,\n * each node weighing its length, read in whichever direction shares more. A\n * pair chain leaves out every node either walk passes twice, which is the\n * whole of a collapsed copy-number array (amylase, KIV-2); the subsequence\n * matches one pass over it, and the other copies are insertions.\n */\nexport function referenceAligner(nodes: Map<number, WalkNode>) {\n  const lengthOf = (handle: number) => nodeLength(nodes, handle >> 1)\n  const offsets = (handles: number[]) => {\n    const out = new Float64Array(handles.length + 1)\n    handles.forEach((handle, i) => {\n      out[i + 1] = out[i]! + lengthOf(handle)\n    })\n    return out\n  }\n\n  return (query: WalkFragment, target: WalkFragment): PairChain[] => {\n    const ref = handlesOf(target)\n    const hap = handlesOf(query)\n    const [same, sameWeight] = weightedLcs(hap, ref, lengthOf)\n    const [turned, turnedWeight] = weightedLcs(\n      hap.map(handle => handle ^ 1).reverse(),\n      ref,\n      lengthOf,\n    )\n    const reverse = turnedWeight > sameWeight\n    const pairs = reverse ? turned : same\n    const sharedBases = Math.max(sameWeight, turnedWeight)\n    if (sharedBases < MIN_MATCH_BP) {\n      return []\n    }\n    const refAt = offsets(ref)\n    const hapAt = offsets(hap)\n    // a pair's haplotype step, counted along the haplotype\n    const stepOf = (k: number) =>\n      reverse ? hap.length - 1 - pairs[k]![0] : pairs[k]![0]\n    const edits: PairEdit[] = []\n    pairs.forEach(([, r], k) => {\n      if (k > 0) {\n        const [lo, hi] = [stepOf(k - 1), stepOf(k)].sort((x, y) => x - y)\n        appendEdit(edits, 'I', hapAt[hi!]! - hapAt[lo! + 1]!)\n        appendEdit(edits, 'D', refAt[r]! - refAt[pairs[k - 1]![1] + 1]!)\n      }\n      appendEdit(edits, '=', lengthOf(ref[r]!))\n    })\n    const [lo, hi] = [stepOf(0), stepOf(pairs.length - 1)].sort((x, y) => x - y)\n    return [\n      {\n        queryStart: hapAt[lo!]!,\n        queryEnd: hapAt[hi! + 1]!,\n        targetStart: refAt[pairs[0]![1]]!,\n        targetEnd: refAt[pairs.at(-1)![1] + 1]!,\n        strand: reverse ? '-' : '+',\n        edits,\n        sharedBases,\n      },\n    ]\n  }\n}\n\n// Each node a walk visits once, with the direction it passes it\nfunction singleVisits(fragment: WalkFragment) {\n  const rev = new Map<number, number>()\n  const twice = new Set<number>()\n  fragment.ids.forEach((id, i) => {\n    if (rev.has(id)) {\n      twice.add(id)\n    } else {\n      rev.set(id, fragment.rev[i]!)\n    }\n  })\n  for (const id of twice) {\n    rev.delete(id)\n  }\n  return rev\n}\n\n// The bases on singly visited nodes two walks pass the same way and the\n// opposite way\nfunction directionShares(nodes: Map<number, WalkNode>) {\n  const visits = new Map<WalkFragment, Map<number, number>>()\n  const visitsOf = (fragment: WalkFragment) => {\n    let found = visits.get(fragment)\n    if (found === undefined) {\n      found = singleVisits(fragment)\n      visits.set(fragment, found)\n    }\n    return found\n  }\n  return (query: WalkFragment, target: WalkFragment) => {\n    const theirs = visitsOf(target)\n    let same = 0\n    let opposite = 0\n    for (const [id, rev] of visitsOf(query)) {\n      const other = theirs.get(id)\n      if (other === rev) {\n        same += nodeLength(nodes, id)\n      } else if (other !== undefined) {\n        opposite += nodeLength(nodes, id)\n      }\n    }\n    return { same, opposite }\n  }\n}\n\n/**\n * Aligns one lane's walk fragment to another's. The weighted subsequence\n * (`referenceAligner`) is the fast route and matches through copy-number\n * arrays, but it reads one direction per pair, so an inversion between the\n * lanes comes out as an insertion beside a deletion. A pair sharing 100 bp\n * (MIN_MATCH_BP) or more of singly visited nodes in each direction goes to\n * pair chaining (`walkAligner`) instead, which answers the inverted stretch as\n * a reverse-strand record of its own. Chaining leaves out every node a walk\n * passes twice, so counting singly visited nodes misses no inversion it could\n * draw.\n */\nexport function lanePairAligner(nodes: Map<number, WalkNode>) {\n  const subsequence = referenceAligner(nodes)\n  const chained = walkAligner(nodes)\n  const shares = directionShares(nodes)\n  return (query: WalkFragment, target: WalkFragment) => {\n    const { same, opposite } = shares(query, target)\n    return same >= MIN_MATCH_BP && opposite >= MIN_MATCH_BP\n      ? chained(query, target)\n      : subsequence(query, target)\n  }\n}\n\n// The multi-way display's SPLIT_AT_GAP_BP, under which a turned stretch names\n// no inversion there\nconst TURNED_MIN_BP = 10_000\n\n/**\n * Aligns a haplotype's walk fragment to the reference's as `referenceAligner`\n * does, then adds the stretches it reads the other way. A walk sharing\n * TURNED_MIN_BP or more of singly visited nodes in each direction is chained\n * too, and the chained records on the strand the subsequence did not take are\n * its turned stretches. The subsequence record stays, so a copy-number array,\n * which chaining leaves out, still matches one pass alike in every lane.\n */\nexport function anchorAligner(nodes: Map<number, WalkNode>) {\n  const subsequence = referenceAligner(nodes)\n  const chained = walkAligner(nodes)\n  const shares = directionShares(nodes)\n  return (query: WalkFragment, target: WalkFragment) => {\n    const records = subsequence(query, target)\n    const taken = records[0]?.strand\n    const { same, opposite } = shares(query, target)\n    return taken === undefined || Math.min(same, opposite) < TURNED_MIN_BP\n      ? records\n      : [\n          ...records,\n          ...chained(query, target).filter(chain => chain.strand !== taken),\n        ]\n  }\n}\n\n/**\n * One record of a walk aligned to another, with its short balanced bubbles as\n * mismatches\n */\nexport function chainFeature({\n  chain,\n  target,\n  query,\n  assemblyName,\n  refName,\n  mateAssemblyName,\n}: {\n  chain: PairChain\n  target: WalkFragment\n  query: WalkFragment\n  assemblyName: string\n  refName: string\n  mateAssemblyName: string\n}) {\n  const edits = bubblesAsMismatches(chain.edits)\n  return matchFeature({\n    target: {\n      name: target.name,\n      assemblyName,\n      refName,\n      start: target.hapStart + chain.targetStart,\n      end: target.hapStart + chain.targetEnd,\n    },\n    query: {\n      name: query.name,\n      assemblyName: mateAssemblyName,\n      refName: panSNContig(query.name),\n      start: query.hapStart + chain.queryStart,\n      end: query.hapStart + chain.queryEnd,\n    },\n    strand: chain.strand,\n    cigar: pairCigar(edits),\n    matches: edits.reduce((sum, [op, n]) => sum + (op === '=' ? n : 0), 0),\n    columns: edits.reduce((sum, [, n]) => sum + n, 0),\n  })\n}\n", "import {\n  assemblyByPanSNPrefix,\n  panSNContig,\n  panSNHaplotype,\n  panSNMatchesPrefix,\n  panSNSample,\n  resolvePanSNPrefix,\n} from '@jbrowse/bandage-core/pansn'\nimport { updateStatus } from '@jbrowse/core/util'\nimport { ObservableCreate } from '@jbrowse/core/util/rxjs'\nimport { walksKept } from '@jbrowse/graph-walks'\n\nimport { anchorAligner, chainFeature, lanePairAligner } from './walkLanes.ts'\nimport { WalkIndex } from '../RgfaTabixAdapter/walkReader.ts'\nimport { PanSNRefNames, openTabixSlot } from '../panSNTabix.ts'\nimport { ComparativeAdapterBase } from '../synteny/ComparativeAdapterBase.ts'\nimport {\n  laneAssemblyName,\n  lanePairsStatus,\n  requestedPairs,\n} from '../synteny/lanePairs.ts'\nimport { laneZoomNotice } from '../synteny/laneZoomNotice.ts'\n\nimport type { WalkTabixSyntenyAdapterConfig } from './configSchema.ts'\nimport type { SubgraphAdapterOptions } from '../GetSubgraph.ts'\nimport type { LaneFeatureOptions, LanePair } from '../synteny/lanePairs.ts'\nimport type { BaseOptions } from '@jbrowse/core/data_adapters/BaseAdapter'\nimport type { Feature } from '@jbrowse/core/util'\nimport type { Region } from '@jbrowse/core/util/types'\nimport type { WalkFragment } from '@jbrowse/graph-walks'\n\nconst haplotypeOf = (fragment: WalkFragment) =>\n  panSNHaplotype(fragment.name) ?? fragment.name\n\nexport default class WalkTabixSyntenyAdapter extends ComparativeAdapterBase<WalkTabixSyntenyAdapterConfig> {\n  private readonly walks: WalkIndex = new WalkIndex(\n    openTabixSlot(this, ['walksLocation'], ['walksIndex']),\n    this,\n  )\n  private readonly refNames: PanSNRefNames = new PanSNRefNames(\n    this.walks.file,\n    this,\n  )\n\n  private get anchor() {\n    const anchor = this.getConf('assemblyNames')[0]\n    if (anchor === undefined) {\n      throw new Error(\n        'WalkTabixSyntenyAdapter needs assemblyNames: its first entry is the assembly the reference sample is loaded as',\n      )\n    }\n    return anchor\n  }\n\n  /**\n   * The haplotypes the walk file's header names, `sample#haplotype` in byte\n   * order, or undefined when it names none\n   */\n  async getHaplotypeNames(opts: BaseOptions = {}) {\n    return this.walks.haplotypeNames(opts)\n  }\n\n  /**\n   * `lanes` is every haplotype the header names but the anchor's own,\n   * declared up front so the display can offer the whole graph's haplotypes\n   * before a fetch has placed any of them\n   */\n  async getHeader(opts: BaseOptions = {}) {\n    const { haplotypes } = await this.walks.reader.header(opts)\n    const { anchor } = this\n    const anchorPrefix = resolvePanSNPrefix(this, anchor)\n    const asmByPrefix = assemblyByPanSNPrefix(this)\n    return {\n      hasCoarseTier: false,\n      anchorAssemblyName: anchor,\n      lanes: haplotypes\n        .filter(\n          prefix =>\n            prefix !== anchorPrefix && panSNSample(prefix) !== anchorPrefix,\n        )\n        .map(prefix => ({\n          name: laneAssemblyName(asmByPrefix, prefix),\n          label: prefix,\n          group: panSNSample(prefix),\n        })),\n    }\n  }\n\n  // A lane's contigs are named only in its walk rows, so only the anchor's\n  // are listed\n  async getRefNames(opts: BaseOptions = {}) {\n    const { assemblyName } = opts\n    return assemblyName === undefined || assemblyName === this.anchor\n      ? this.refNames.assemblyRefNames({ ...opts, assemblyName: this.anchor })\n      : []\n  }\n\n  /**\n   * The graph display's cut of the window, as RgfaTabixAdapter cuts a\n   * walk-indexed graph: the reference walk first, then the walks `haplotypes`\n   * asks for, and the nodes and links they visit\n   */\n  async getSubgraph(region: Region, opts: SubgraphAdapterOptions = {}) {\n    const refName = await this.refNames.resolveForCut(region, {\n      signal: opts.signal,\n    })\n    return this.walks.subgraph(refName, region, opts)\n  }\n\n  // The window's walks for the haplotypes named and the reference, with no\n  // link read; a window past a budget fails as a zoom-in notice for lanes.\n  // Named lanes come back in full where format 5 abridged them: an abridged\n  // walk is two reference steps, which drew 15 of the HPRC MHC launch's 32\n  // lanes empty.\n  private async laneWalks(\n    refName: string,\n    region: Region,\n    prefixes: string[] | undefined,\n    opts: LaneFeatureOptions,\n    status: string,\n  ) {\n    const keep = walksKept(prefixes, refName)\n    return updateStatus(status, opts.statusCallback, () =>\n      this.walks.reader\n        .cut(refName, region, {\n          ...this.walks.budgets(),\n          signal: opts.signal,\n          keep,\n          expand: keep,\n          links: false,\n        })\n        .catch((error: unknown) => {\n          throw laneZoomNotice(error, region.end - region.start)\n        }),\n    )\n  }\n\n  /**\n   * One record per stretch a haplotype's walk shares with the reference's,\n   * on the reference with the haplotype as its mate\n   */\n  private async anchorFeatures(\n    refName: string,\n    region: Region,\n    opts: LaneFeatureOptions,\n  ) {\n    const wanted = opts.haplotypes?.length\n      ? opts.haplotypes.map(lane => resolvePanSNPrefix(this, lane))\n      : undefined\n    const target = resolvePanSNPrefix(this, opts.targetAssemblyName)\n    const prefixes =\n      target === undefined\n        ? wanted\n        : wanted === undefined ||\n            wanted.some(\n              prefix =>\n                panSNMatchesPrefix(target, prefix) ||\n                panSNMatchesPrefix(prefix, target),\n            )\n          ? [target]\n          : []\n    if (prefixes?.length === 0) {\n      return []\n    }\n    const { start, end } = region\n    const { graph, fragments } = await this.laneWalks(\n      refName,\n      region,\n      prefixes,\n      opts,\n      `Reading walks ${region.refName}:${start.toLocaleString()}-${end.toLocaleString()}`,\n    )\n    const align = anchorAligner(graph.nodes)\n    const asmByPrefix = assemblyByPanSNPrefix(this)\n    const references = fragments.filter(f => f.name === refName)\n    // lanes come back in the order the fetch names them, which is the order\n    // the display stacks lanes of equal weight in\n    const rank = (fragment: WalkFragment) =>\n      prefixes === undefined\n        ? 0\n        : prefixes.findIndex(prefix =>\n            panSNMatchesPrefix(fragment.name, prefix),\n          )\n    const shown = fragments\n      .filter(fragment => fragment.name !== refName && rank(fragment) >= 0)\n      .sort((a, b) => rank(a) - rank(b))\n    return shown.flatMap(query =>\n      references.flatMap(reference =>\n        align(query, reference).map(chain =>\n          chainFeature({\n            chain,\n            target: reference,\n            query,\n            assemblyName: region.assemblyName,\n            refName: region.refName,\n            mateAssemblyName: laneAssemblyName(asmByPrefix, haplotypeOf(query)),\n          }),\n        ),\n      ),\n    )\n  }\n\n  /**\n   * Each pair's two lanes read out of the anchor window, all pairs in one\n   * read, and each walk of a pair's query lane aligned to each walk of its\n   * target lane. A pair's records sit on its query lane's contigs, the lane\n   * the display draws on top.\n   */\n  private async pairFeatures(\n    refName: string,\n    region: Region,\n    pairs: LanePair[],\n    opts: LaneFeatureOptions,\n  ) {\n    const sides = pairs.map(pair => ({\n      pair,\n      featurePrefix: resolvePanSNPrefix(this, pair.queryAssemblyName),\n      matePrefix: resolvePanSNPrefix(this, pair.targetAssemblyName),\n    }))\n    const { graph, fragments } = await this.laneWalks(\n      refName,\n      region,\n      sides.flatMap(side => [side.featurePrefix, side.matePrefix]),\n      opts,\n      lanePairsStatus(pairs),\n    )\n    const align = lanePairAligner(graph.nodes)\n    const walksOf = (prefix: string) =>\n      fragments.filter(f => panSNMatchesPrefix(f.name, prefix))\n    return sides.flatMap(({ pair, featurePrefix, matePrefix }) =>\n      walksOf(featurePrefix).flatMap(target =>\n        walksOf(matePrefix).flatMap(query =>\n          align(query, target).map(chain =>\n            chainFeature({\n              chain,\n              target,\n              query,\n              assemblyName: pair.queryAssemblyName,\n              refName: panSNContig(target.name),\n              mateAssemblyName: pair.targetAssemblyName,\n            }),\n          ),\n        ),\n      ),\n    )\n  }\n\n  // The files are filed under the reference alone, so a window on a\n  // haplotype lane has no answer: a lane pair is read inside the anchor's\n  getFeatures(region: Region, opts: LaneFeatureOptions = {}) {\n    return ObservableCreate<Feature>(async observer => {\n      const refName =\n        region.assemblyName === this.anchor\n          ? await this.refNames.resolve(region, opts)\n          : undefined\n      if (refName !== undefined) {\n        const pairs = requestedPairs(opts)\n        const features =\n          pairs.length > 0\n            ? await this.pairFeatures(refName, region, pairs, opts)\n            : await this.anchorFeatures(refName, region, opts)\n        for (const feature of features) {\n          observer.next(feature)\n        }\n      }\n      observer.complete()\n    }, opts.signal)\n  }\n}\n"],
-  "mappings": 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-}

package/dist/chunks/chunk-EENENDGZ.js

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k=`${h.name}	${h.fragStart}`,F=f.get(k);F?F.push(h):f.set(k,[h])}let w=new Map;for(let h of f.values())h.sort((k,F)=>k.firstPiece-F.firstPiece),h.forEach((k,F)=>{w.set(k,[h[F-1],h[F+1]])});let b=new Map,y=h=>{var k,F;let L=b.get(h);return L===void 0&&(L=h.hapOffset+((F=(k=h.abridged)===null||k===void 0?void 0:k.bp)!==null&&F!==void 0?F:x(h.ids,0,h.ids.length)),b.set(h,L)),L},R=(h,k,F)=>{var L;let N=F>0?{trimmed:F}:{},v=k?h.next:h.prev;if(v){let G=(L=w.get(h))===null||L===void 0?void 0:L[k?1:0];return G?{kind:"elsewhere",chunk:v,bp:k?G.hapOffset-y(h):h.hapOffset-y(G),...N}:{kind:"elsewhere",chunk:v,...N}}let _=k?h.nextRecord:h.prevRecord;return _?{kind:"break",..._,...N}:{kind:"end",...N}},U=[];for(let{run:h,first:k,last:F}of Q){let{ids:L,rev:N}=h;if(D.has(h)){U.push({name:h.name,fragStart:h.fragStart,hapStart:h.hapOffset,hapEnd:y(h),ids:L,rev:N,before:R(h,!1,0),after:R(h,!0,0),abridged:h.abridged});continue}let v=k,_=F;for(;v>0&&C.has(L[v-1]);)v--;for(;_<L.length-1&&C.has(L[_+1]);)_++;let G=h.hapOffset+x(L,0,v),H=G+x(L,v,_+1);U.push({name:h.name,fragStart:h.fragStart,hapStart:G,hapEnd:H,ids:L.subarray(v,_+1),rev:N.subarray(v,_+1),before:R(h,!1,G-h.hapOffset),after:R(h,!0,y(h)-H)})}return{kept:C,fragments:U,open:[...s.values()]}}function nt(t,e,A,n){var r;for(let i of t.nodes.keys())!((r=e.get(i))===null||r===void 0)&&r.onWindow&&n.add(i);for(let{steps:i}of t.rows){let{ids:o}=i,s=-1;for(let c=0;c<o.length;c++){let a=e.get(o[c]);if(a?.onWindow){for(let g=s+1;s>=0&&g<c;g++)n.add(o[g]);s=c}else A&&a?.rank===0&&(s=-1)}}}function mn(t){let e=[],A=new Map,n={kinds:new Uint8Array(t.length),kindNames:[...pn],bp:new Float64Array(t.length).fill(Number.NaN),trimmed:new Float64Array(t.length),chunkRefs:new Int32Array(t.length).fill(-1),chunkStarts:new Float64Array(t.length).fill(Number.NaN),chunkRefNames:e};return t.forEach((r,i)=>{var o;if(n.kinds[i]=pn.indexOf(r.kind),n.trimmed[i]=(o=r.trimmed)!==null&&o!==void 0?o:0,"bp"in r&&r.bp!==void 0&&(n.bp[i]=r.bp),"chunk"in r&&r.chunk){let{refName:s,start:c}=r.chunk,a=A.get(s);a===void 0&&(a=e.length,A.set(s,a),e.push(s)),n.chunkRefs[i]=a,n.chunkStarts[i]=c}}),n}var Hi=(t,e)=>t.rank===0&&(e.rank!==0||t.refName<e.refName||t.refName===e.refName&&t.start<e.start),jA=class{constructor(e){this.nodes=new Map,this.sequences=new Map,this.links=[],this.chunks=[],this.window=e}placeNode(e,A){let n=this.nodes.get(e);if(n&&!Hi(A,n))return;let{window:r}=this;this.nodes.set(e,{...A,onWindow:A.rank===0&&A.refName===r.refName&&A.end>r.start-r.context&&A.start<r.end+r.context})}addLinkEnds(e,A){this.links.push(e,A)}addChunk(e){this.chunks.push(e)}addSequences(e){if(this.window.sequences)for(let[A,n]of e)this.sequences.set(A,n)}tables(e,A,n=[]){this.chunks.length>0&&hn(this.chunks,e,(f,w)=>{let b=this.nodes.get(f);b&&this.nodes.set(f,{...b,...w})},(f,w)=>{this.links.push(f,w)});let r=[];for(let f of e){let w=this.nodes.get(f);w&&r.push({...w,id:f})}r.sort((f,w)=>f.refName<w.refName?-1:f.refName>w.refName?1:f.start-w.start||f.id-w.id);let i=new Map,o=[],s=[],c=new Map,a=new Int32Array(r.length),g=new Int32Array(r.length),l=new Float64Array(r.length),Q=new Int32Array(r.length);r.forEach(({id:f,refName:w,start:b,end:y,rank:R},U)=>{i.set(f,U),o.push(String(f));let h=c.get(w);h===void 0&&(h=s.length,c.set(w,h),s.push(w)),a[U]=y-b,g[U]=h,l[U]=b,Q[U]=R});let I=f=>{let w=i.get(f);return w===void 0&&(w=o.length,i.set(f,w),o.push(String(f))),w},B=new Map;for(let f=0;f<this.links.length;f+=2){let w=this.links[f],b=this.links[f+1],y=Math.floor(w/2),R=Math.floor(b/2);e.has(y)&&e.has(R)&&B.set(`${y}	${w%2?"-":"+"}	${R}	${b%2?"-":"+"}`,f)}let E=[...B.keys()].sort(),d=new Int32Array(E.length),p=new Int32Array(E.length),u=new Uint8Array(E.length);E.forEach((f,w)=>{let b=B.get(f),y=this.links[b],R=this.links[b+1];d[w]=I(Math.floor(y/2)),p[w]=I(Math.floor(R/2)),u[w]=y%2|R%2<<1});let m=this.referenceFirst(A),C=new Int32Array(m.length+1);m.forEach(({ids:f},w)=>{C[w+1]=C[w]+f.length});let D=new Int32Array(C[m.length]),x=new Uint8Array(D.length);return m.forEach(({ids:f,rev:w},b)=>{let y=C[b];for(let R=0;R<f.length;R++)D[y+R]=I(f[R]);x.set(w,y)}),{nodes:{names:o,lengths:a,refs:g,starts:l,ranks:Q,refNames:s},links:{from:d,to:p,strands:u},walks:{names:m.map(f=>f.name),starts:Float64Array.from(m,f=>f.hapStart),ends:Float64Array.from(m,f=>f.hapEnd),offsets:C,steps:D,reversed:x,before:mn(m.map(f=>f.before)),after:mn(m.map(f=>f.after)),abridgedSteps:Float64Array.from(m,f=>{var w,b;return(b=(w=f.abridged)===null||w===void 0?void 0:w.steps)!==null&&b!==void 0?b:NaN}),abridgedBp:Float64Array.from(m,f=>{var w,b;return(b=(w=f.abridged)===null||w===void 0?void 0:w.bp)!==null&&b!==void 0?b:NaN})},skips:{names:n.map(f=>f.name),starts:Float64Array.from(n,f=>f.refStart),ends:Float64Array.from(n,f=>f.refEnd)}}}referenceFirst(e){let{refName:A}=this.window;return[...e].sort((n,r)=>+(r.name===A)-+(n.name===A)||(n.name<r.name?-1:n.name>r.name?1:n.hapStart-r.hapStart))}},rt={steps:"the step budget",bytes:"a byte budget of"},Ki=4,Ti=t=>{var e;let A=(e=t.interior)!==null&&e!==void 0?e:0;return A+(t.n-A)/Ki};function it(t,e,A,n,r,i,o=rt){var s;let c=0,a=new Map,g=new Set;for(let d of t){let p=Ti(d);c+=p,a.set(d.chunkStart,((s=a.get(d.chunkStart))!==null&&s!==void 0?s:0)+p),g.add(d.name)}let l=e*A;if(c<=l)return;let Q=n.end-n.start,I=0,B=0;for(let d of[...a.keys()].sort((p,u)=>p-u)){if(I+=a.get(d),I>l)break;B=Math.max(B,d+r-n.start)}let E=!i&&g.size>2&&2*c/g.size<=l;return new aA(B>0?`Zoom in to about ${NA(B)}${E?", or choose fewer haplotypes,":""} to see the graph`:`Too many haplotype steps here to draw ${i?"these haplotypes":"every haplotype"} (${Math.round(I).toLocaleString()} steps read, a step along the reference counting a quarter, over ${A} \xD7 ${o.steps} of ${e.toLocaleString()}); choose fewer haplotypes`,l,Q,Math.max(B,1))}function ot(t,e,A,n){let r=t.reduce((i,o)=>i+o.ids.length,0);return bn(r,e,A,n)}function Qe(t,e,A,n,r=A.end){return bn(t,e,A,n,r)}function bn(t,e,A,n,r=A.end){if(t<=e)return;let i=A.end-A.start,o=Math.min(r,A.end)-A.start,s=Math.max(1,Math.floor(o*e/t));return new aA(`Zoom in to about ${NA(s)}${n?"":", or choose fewer haplotypes,"} to see the graph`,e,i,s)}async function st(t,e,A,n,r=rt){let i=await t(A.end);if(i<=e)return;let o=0,s;for(let a=Math.floor(A.start/n)*n;a<A.end;a+=n){let g=await t(a+1);if(s??(s=g),g>e)break;o=a+n-A.start}let c=A.end-A.start;return o>0?new aA(`Zoom in to about ${NA(o)} to see the graph`,e,c,o,{bytes:i,zoomHelps:!0}):new aA(`Too much graph here to fetch, even zoomed in (${kn(s??i)} against ${r.bytes} ${kn(e)}). A satellite or rDNA array usually causes this: the graph folds the repeat into a few nodes that each haplotype loops through many times`,e,c,1,{bytes:i})}var kn=t=>`${(t/1e6).toFixed(1)} MB`;function at(t,e){return`${t}	${e}`}function WA(t){let e=new Map;for(let A of t){e.set(A,A);let n=XA(A);if(n!==A){let r=Pe(A);e.set(at(n,r),A);let i=hA(A);i!==void 0&&e.set(at(i,r),A)}}return e}function VA(t,e,A){var n;return(n=t.get(at(e,A)))!==null&&n!==void 0?n:t.get(A)}var Oi=8,qi=3,Zi=4,Pi=1e3,zi=16,Xi={stepBudget:4e6,byteBudget:8e6},le=class extends Error{constructor(){super(...arguments),this.name="WalkFormatError"}};function fA(t,e,A){if(!Number.isFinite(e)||!Number.isFinite(A))throw new Error(`${t}:${e}-${A} is not a finite range to query the graph's index for`)}function xn(t){return t.filter(e=>!e.includes("~"))}async function ji(t,e,A,n,r){let i=[],o=()=>{if(i.length<t.length&&!A.aborted){let s=n(t[i.length]);i.push(s),s.then(o,()=>{})}};for(let s=0;s<e;s++)o();for(let s=0;s<t.length;s++)A.throwIfAborted(),r(t[s],await i[s])}function Dn(t,e){return e?(e.throwIfAborted(),new Promise((A,n)=>{let r=()=>{n(e.reason instanceof Error?e.reason:new Error(String(e.reason)))};e.addEventListener("abort",r,{once:!0}),t.then(A,n).finally(()=>{e.removeEventListener("abort",r)})})):t}var gt=class{constructor(e){this.walks=e}header(e={}){if(!this.headerRead){let A=this.walks.getHeaderLines().then(n=>{var r,i;let o=$e(n);if(o.format!==5)throw new le(`This walk file is format ${(r=o.format)!==null&&r!==void 0?r:1}; @jbrowse/graph-walks reads format 5, so rebuild it with gfa-to-tabix 1.4 or later`);return{...o,chunk:(i=o.chunk)!==null&&i!==void 0?i:65536}});A.catch(()=>{this.headerRead===A&&(this.headerRead=void 0)}),this.headerRead=A}return Dn(this.headerRead,e.signal)}async referenceSequences(e={}){return xn(await this.walks.getReferenceSequenceNames(e))}async sequenceFor(e,A,n={}){if(!this.lookupRead){let i=this.walks.getReferenceSequenceNames().then(o=>WA(xn(o)));i.catch(()=>{this.lookupRead===i&&(this.lookupRead=void 0)}),this.lookupRead=i}let r=await Dn(this.lookupRead,n.signal);return VA(r,e,A)}async queryStart(e,A={}){let{refName:n="",end:r=e+1}=A;return Ce(await this.header(A),n,e,r)}async cut(e,A,n={}){var r,i;let{signal:o,keep:s,context:c=Pi,stepBudget:a=1/0,byteBudget:g=1/0,links:l=!0,contained:Q=!1,nodeLimit:I=1/0,expand:B}=n,E=await this.header({signal:o}),{chunk:d}=E,p=Ce(E,e,A.start,A.end),u=(r=this.walks.bytesForRegions)===null||r===void 0?void 0:r.bind(this.walks),m=Number.isFinite(g)&&u!==void 0,C=async S=>m?u(S.map(J=>({refName:e,...J})),{signal:o}):0,D=m?await st(async S=>(fA(e,p,S),C([{start:p,end:S}])),g,A,d,n.budgetNames):void 0;if(D)throw D;let x=new AbortController,f=()=>{x.abort(o?.reason)};o?.throwIfAborted(),o?.addEventListener("abort",f,{once:!0});let w=[],b,y=new jA({refName:e,start:A.start,end:A.end,context:c,sequences:n.sequences}),R=new Set,U=[],h=[],k=new Set,F=s!==void 0,L=[],N=(S,J)=>{if(R.has(S))return;R.add(S);let M=We(J,s,n.sequences);for(let K of M.skips)h.push(K);let Y;for(let K of M.rows)K.abridged&&B?.(K.name)?(Y??(Y=dn(J)),L.push({ref:Y,row:K})):w.push(K);G(M,S)},v=async({row:S})=>{let{refName:J,start:M}=S.abridged.detail;fA(J,M,M+1);let Y=[];return await this.walks.getLines(J,M,M+1,{signal:x.signal,lineCallback:K=>{let j=K.split("	");j[0]=e,j[1]=String(S.chunkStart),Y.push(j)}}),Y},_=({ref:S,row:J},M)=>{let Y=We(M,K=>K===J.name,n.sequences,S);for(let K of Y.rows)K.name===J.name&&w.push(K);G(Y,J.chunkStart)},G=(S,J)=>{for(let[M,Y]of S.nodes)y.placeNode(M,Y);y.addSequences(S.sequences),y.addChunk(S.chunk);for(let M of S.ends)U.push(M);if(Number.isFinite(I)){nt(S,y.nodes,Q,k),k.size>I&&(k.clear(),nt({nodes:y.nodes,rows:w},y.nodes,Q,k));let M=Qe(k.size,I,A,F,J+d);if(M)throw M}},H=async(S,J)=>{fA(e,S,J);let M,Y=[];await this.walks.getLines(e,S,J,{signal:x.signal,lineCallback:j=>{let W=j.split("	"),eA=+W[1];eA!==M&&(M!==void 0&&N(M,Y),M=eA,Y=[]),Y.push(W)}}),M!==void 0&&N(M,Y);let K=L;if(L=[],await ji(K,zi,x.signal,v,_),l)for(let[j,W]of un(U))y.addLinkEnds(j,W)};try{await H(p,A.end);let S=it(w,a,Oi,A,d,F,n.budgetNames);if(S)throw S;let J=p,M=Math.floor((A.end-1)/d)*d,Y=Zi*d,[K,j]=Q?[Math.floor((A.start-c)/d)*d,Math.floor((A.end+c-1)/d)*d]:[J-Y,M+Y],W=()=>tt(et(w),y.nodes,e,{contained:Q,context:c});b=W();let eA=await C([{start:p,end:A.end}]);for(let tA=0;tA<qi;tA++){let V=J,X=M;for(let O of b.open)O.refName===e&&O.start>=K&&O.start<=j&&(V=Math.min(V,O.start),X=Math.max(X,O.start));let T=[{start:V,end:J},{start:M+d,end:X+1}].filter(O=>O.end>O.start);if(T.length===0||(eA+=await C(T),eA>g))break;J=V,M=X,await Promise.all(T.map(({start:O,end:dA})=>H(O,dA))),b=W()}}catch(S){throw x.abort(),S}finally{o?.removeEventListener("abort",f)}let z=(i=ot(b.fragments,a,A,F))!==null&&i!==void 0?i:Qe(b.kept.size,I,A,F);if(z)throw z;return{graph:y,...b,skips:Bn(h,b.fragments,A)}}async cutRegion(e,A={}){var n;let{haplotypes:r,referenceSample:i,...o}=A,{signal:s}=A,c=await this.header({signal:s}),a=(n=i??c.references[0])!==null&&n!==void 0?n:"",g=await this.sequenceFor(a,e.refName,{signal:s});if(g===void 0){let E=await this.referenceSequences({signal:s});throw new Error(`The walk file has no sequence ${e.refName} on ${a}; it holds ${E.slice(0,5).join(", ")}${E.length>5?", \u2026":""}`)}let{graph:l,kept:Q,fragments:I,skips:B}=await this.cut(g,e,{...o,keep:At(r,g)});return{tables:l.tables(Q,I,B),refName:g,sample:a}}};var bA=50,Ln=[50,1e3,1e4],It=.05,Wi=1e3,Vi=.1,Be="0",sA=".",Ee="~";function Jn(t){let e=t/100,[A,n,r]=Ln;return e<250?A:e<3e3?n:r}var Gn=t=>Math.max(1,Math.round(t/100));function ft(t,e){return e>t&&t<bA?"insertion":e<t&&e<bA?"deletion":"replacement"}function Ct(t,e){return e<It*t?"deletion":t<It*e?"insertion":void 0}var Un=(t,e,A)=>{let n=t==="replacement"?Ct(e,A):void 0;return n?{lopsided:n}:{}},Yn=t=>10**(Math.floor(Math.log10(t))-1),KA=t=>{let e=Yn(t);return Math.round(Math.round(t/e)*e)},Hn=(t,e=0)=>Math.abs(t.delta)>=Math.max(e,Yn(t.shiftedBp));function Kn(t,e=bA){let A=t.delta>0?"+":"-";switch(t.kind){case"inversion":return`v${KA(Math.max(Math.abs(t.delta),t.refEnd-t.refStart,1))}`;case"shift":return Hn(t,e)?`s${KA(t.shiftedBp)}${A}${KA(Math.abs(t.delta))}`:`s${KA(t.shiftedBp)}`;case"net":return`n${A}${KA(Math.abs(t.delta))}`;default:return`${A}${KA(Math.abs(t.delta))}`}}var Sn=t=>t.altLength-(t.refEnd-t.refStart);function $i(t,e){let A=[];for(let n of t){let r=A.at(-1);r&&!r.abridged&&!n.abridged&&n.refStart-r.refEnd<e?(r.refEnd=Math.max(r.refEnd,n.refEnd),r.delta+=Sn(n),r.invertedBp+=n.invertedBp,r.repeatedBp+=n.repeatedBp,n.copied&&(r.copied=r.copied?[Math.min(r.copied[0],n.copied[0]),Math.max(r.copied[1],n.copied[1])]:n.copied)):A.push({refStart:n.refStart,refEnd:n.refEnd,delta:Sn(n),invertedBp:n.invertedBp,repeatedBp:n.repeatedBp,...n.copied?{copied:n.copied}:{},...n.abridged?{abridged:!0}:{}})}return A}function Ao(t,e){let 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zr(t,e,A,n){var r,i=t.state;return i.window===null&&(i.wsize=1<<i.wbits,i.wnext=0,i.whave=0,i.window=CA(i.wsize)),n>=i.wsize?(cA(i.window,e,A-i.wsize,i.wsize,0),i.wnext=0,i.whave=i.wsize):(r=i.wsize-i.wnext,r>n&&(r=n),cA(i.window,e,A-n,r,i.wnext),n-=r,n?(cA(i.window,e,A-n,n,0),i.wnext=n,i.whave=i.wsize):(i.wnext+=r,i.wnext===i.wsize&&(i.wnext=0),i.whave<i.wsize&&(i.whave+=r))),0}function Xr(t,e){var A,n,r,i,o,s,c,a,g,l,Q,I,B,E,d=0,p,u,m,C,D,x,f,w,b=CA(4),y,R,U=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15];if(!t||!t.state||!t.output||!t.input&&t.avail_in!==0)return rA;A=t.state,A.mode===QA&&(A.mode=xt),o=t.next_out,r=t.output,c=t.avail_out,i=t.next_in,n=t.input,s=t.avail_in,a=A.hold,g=A.bits,l=s,Q=c,w=SA;A:for(;;)switch(A.mode){case Zr:if(A.wrap===0){A.mode=xt;break}for(;g<16;){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}if(A.wrap&2&&a===35615){A.check=0,b[0]=a&255,b[1]=a>>>8&255,A.check=nA(A.check,b,2,0),a=0,g=0,A.mode=ur;break}if(A.flags=0,A.head&&(A.head.done=!1),!(A.wrap&1)||(((a&255)<<8)+(a>>8))%31){t.msg="incorrect header check",A.mode=Z;break}if((a&15)!==hr){t.msg="unknown compression method",A.mode=Z;break}if(a>>>=4,g-=4,f=(a&15)+8,A.wbits===0)A.wbits=f;else if(f>A.wbits){t.msg="invalid window size",A.mode=Z;break}A.dmax=1<<f,t.adler=A.check=1,A.mode=a&512?xr:QA,a=0,g=0;break;case ur:for(;g<16;){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}if(A.flags=a,(A.flags&255)!==hr){t.msg="unknown compression method",A.mode=Z;break}if(A.flags&57344){t.msg="unknown header flags set",A.mode=Z;break}A.head&&(A.head.text=a>>8&1),A.flags&512&&(b[0]=a&255,b[1]=a>>>8&255,A.check=nA(A.check,b,2,0)),a=0,g=0,A.mode=pr;case pr:for(;g<32;){if(s===0)break 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f=n[i+I++],A.head&&f&&A.length<65536&&(A.head.name+=String.fromCharCode(f));while(f&&I<s);if(A.flags&512&&(A.check=nA(A.check,n,I,i)),s-=I,i+=I,f)break A}else A.head&&(A.head.name=null);A.length=0,A.mode=Nr;case Nr:if(A.flags&4096){if(s===0)break A;I=0;do f=n[i+I++],A.head&&f&&A.length<65536&&(A.head.comment+=String.fromCharCode(f));while(f&&I<s);if(A.flags&512&&(A.check=nA(A.check,n,I,i)),s-=I,i+=I,f)break A}else A.head&&(A.head.comment=null);A.mode=br;case br:if(A.flags&512){for(;g<16;){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}if(a!==(A.check&65535)){t.msg="header crc mismatch",A.mode=Z;break}a=0,g=0}A.head&&(A.head.hcrc=A.flags>>9&1,A.head.done=!0),t.adler=A.check=0,A.mode=QA;break;case xr:for(;g<32;){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}t.adler=A.check=Hr(a),a=0,g=0,A.mode=be;case be:if(A.havedict===0)return t.next_out=o,t.avail_out=c,t.next_in=i,t.avail_in=s,A.hold=a,A.bits=g,Go;t.adler=A.check=1,A.mode=QA;case QA:if(e===Lo||e===ke)break A;case xt:if(A.last){a>>>=g&7,g-=g&7,A.mode=St;break}for(;g<3;){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}switch(A.last=a&1,a>>>=1,g-=1,a&3){case 0:A.mode=Dr;break;case 1:if(Po(A),A.mode=ye,e===ke){a>>>=2,g-=2;break A}break;case 2:A.mode=vr;break;case 3:t.msg="invalid block type",A.mode=Z}a>>>=2,g-=2;break;case Dr:for(a>>>=g&7,g-=g&7;g<32;){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}if((a&65535)!==(a>>>16^65535)){t.msg="invalid stored block lengths",A.mode=Z;break}if(A.length=a&65535,a=0,g=0,A.mode=Dt,e===ke)break A;case Dt:A.mode=Sr;case Sr:if(I=A.length,I){if(I>s&&(I=s),I>c&&(I=c),I===0)break A;cA(r,n,i,I,o),s-=I,i+=I,c-=I,o+=I,A.length-=I;break}A.mode=QA;break;case vr:for(;g<14;){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}if(A.nlen=(a&31)+257,a>>>=5,g-=5,A.ndist=(a&31)+1,a>>>=5,g-=5,A.ncode=(a&15)+4,a>>>=4,g-=4,A.nlen>286||A.ndist>30){t.msg="too many length or distance symbols",A.mode=Z;break}A.have=0,A.mode=Fr;case Fr:for(;A.have<A.ncode;){for(;g<3;){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}A.lens[U[A.have++]]=a&7,a>>>=3,g-=3}for(;A.have<19;)A.lens[U[A.have++]]=0;if(A.lencode=A.lendyn,A.lenbits=7,y={bits:A.lenbits},w=DA(Mo,A.lens,0,19,A.lencode,0,A.work,y),A.lenbits=y.bits,w){t.msg="invalid code lengths set",A.mode=Z;break}A.have=0,A.mode=Rr;case Rr:for(;A.have<A.nlen+A.ndist;){for(;d=A.lencode[a&(1<<A.lenbits)-1],p=d>>>24,u=d>>>16&255,m=d&65535,!(p<=g);){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}if(m<16)a>>>=p,g-=p,A.lens[A.have++]=m;else{if(m===16){for(R=p+2;g<R;){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}if(a>>>=p,g-=p,A.have===0){t.msg="invalid bit length repeat",A.mode=Z;break}f=A.lens[A.have-1],I=3+(a&3),a>>>=2,g-=2}else if(m===17){for(R=p+3;g<R;){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}a>>>=p,g-=p,f=0,I=3+(a&7),a>>>=3,g-=3}else{for(R=p+7;g<R;){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}a>>>=p,g-=p,f=0,I=11+(a&127),a>>>=7,g-=7}if(A.have+I>A.nlen+A.ndist){t.msg="invalid bit length repeat",A.mode=Z;break}for(;I--;)A.lens[A.have++]=f}}if(A.mode===Z)break;if(A.lens[256]===0){t.msg="invalid code -- missing end-of-block",A.mode=Z;break}if(A.lenbits=9,y={bits:A.lenbits},w=DA(Tr,A.lens,0,A.nlen,A.lencode,0,A.work,y),A.lenbits=y.bits,w){t.msg="invalid literal/lengths set",A.mode=Z;break}if(A.distbits=6,A.distcode=A.distdyn,y={bits:A.distbits},w=DA(Or,A.lens,A.nlen,A.ndist,A.distcode,0,A.work,y),A.distbits=y.bits,w){t.msg="invalid distances set",A.mode=Z;break}if(A.mode=ye,e===ke)break A;case ye:A.mode=Ne;case Ne:if(s>=6&&c>=258){t.next_out=o,t.avail_out=c,t.next_in=i,t.avail_in=s,A.hold=a,A.bits=g,Nt(t,Q),o=t.next_out,r=t.output,c=t.avail_out,i=t.next_in,n=t.input,s=t.avail_in,a=A.hold,g=A.bits,A.mode===QA&&(A.back=-1);break}for(A.back=0;d=A.lencode[a&(1<<A.lenbits)-1],p=d>>>24,u=d>>>16&255,m=d&65535,!(p<=g);){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}if(u&&(u&240)===0){for(C=p,D=u,x=m;d=A.lencode[x+((a&(1<<C+D)-1)>>C)],p=d>>>24,u=d>>>16&255,m=d&65535,!(C+p<=g);){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}a>>>=C,g-=C,A.back+=C}if(a>>>=p,g-=p,A.back+=p,A.length=m,u===0){A.mode=Gr;break}if(u&32){A.back=-1,A.mode=QA;break}if(u&64){t.msg="invalid literal/length code",A.mode=Z;break}A.extra=u&15,A.mode=_r;case _r:if(A.extra){for(R=A.extra;g<R;){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}A.length+=a&(1<<A.extra)-1,a>>>=A.extra,g-=A.extra,A.back+=A.extra}A.was=A.length,A.mode=Mr;case Mr:for(;d=A.distcode[a&(1<<A.distbits)-1],p=d>>>24,u=d>>>16&255,m=d&65535,!(p<=g);){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}if((u&240)===0){for(C=p,D=u,x=m;d=A.distcode[x+((a&(1<<C+D)-1)>>C)],p=d>>>24,u=d>>>16&255,m=d&65535,!(C+p<=g);){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}a>>>=C,g-=C,A.back+=C}if(a>>>=p,g-=p,A.back+=p,u&64){t.msg="invalid distance code",A.mode=Z;break}A.offset=m,A.extra=u&15,A.mode=Lr;case Lr:if(A.extra){for(R=A.extra;g<R;){if(s===0)break A;s--,a+=n[i++]<<g,g+=8}A.offset+=a&(1<<A.extra)-1,a>>>=A.extra,g-=A.extra,A.back+=A.extra}if(A.offset>A.dmax){t.msg="invalid distance too far back",A.mode=Z;break}A.mode=Jr;case Jr:if(c===0)break A;if(I=Q-c,A.offset>I){if(I=A.offset-I,I>A.whave&&A.sane){t.msg="invalid distance too far back",A.mode=Z;break}I>A.wnext?(I-=A.wnext,B=A.wsize-I):B=A.wnext-I,I>A.length&&(I=A.length),E=A.window}else E=r,B=o-A.offset,I=A.length;I>c&&(I=c),c-=I,A.length-=I;do r[o++]=E[B++];while(--I);A.length===0&&(A.mode=Ne);break;case Gr:if(c===0)break A;r[o++]=A.length,c--,A.mode=Ne;break;case St:if(A.wrap){for(;g<32;){if(s===0)break A;s--,a|=n[i++]<<g,g+=8}if(Q-=c,t.total_out+=Q,A.total+=Q,Q&&(t.adler=A.check=A.flags?nA(A.check,r,Q,o-Q):ie(A.check,r,Q,o-Q)),Q=c,(A.flags?a:Hr(a))!==A.check){t.msg="incorrect data check",A.mode=Z;break}a=0,g=0}A.mode=Ur;case Ur:if(A.wrap&&A.flags){for(;g<32;){if(s===0)break 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A=e.length,n,r,i;return!t||!t.state||(n=t.state,n.wrap!==0&&n.mode!==be)?rA:n.mode===be&&(r=1,r=ie(r,e,A,0),r!==n.check)?qr:(i=zr(t,e,A,A),i?(n.mode=_t,Rt):(n.havedict=1,SA))}var xe={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible version"};function Lt(){this.input=null,this.next_in=0,this.avail_in=0,this.total_in=0,this.output=null,this.next_out=0,this.avail_out=0,this.total_out=0,this.msg="",this.state=null,this.data_type=2,this.adler=0}var Jt=Object.prototype.toString,Gt=class t{constructor(e){if(!(this instanceof t))return new t(e);this.options=sr({chunkSize:16384,windowBits:0,to:""},e||{});var 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this.index.blocksForRange(e,g,l,o)),I=a.format==="VCF",B=a.columnNumbers.ref||0,E=a.columnNumbers.start||0,d=I?8:a.columnNumbers.end||0,p=Math.max(B,E,d),u=a.metaChar?.charCodeAt(0),m=a.coordinateType==="1-based-closed"?-1:0,C=new TextEncoder,D=new TextDecoder,x=C.encode(e),f=new Int32Array(p+1),w=a.format==="GAF"?{start:g,end:l,pathCol:E,metaCharCode:u,decoder:D,callback:s}:void 0,b=0;for(let k of Q)b+=k.fetchedSize();let y=0;c?.(0,b);let R=1,U=[],h=k=>{for(;U.length<Math.min(k,Q.length);){let F=Q[U.length];this.requested.set(F.toString(),F);let L=this.chunkCache.get(F,i);L.catch(()=>{}),U.push(L)}};h(1);for(let k=0,F=Q.length;k<F;k++){let L=Q[k],{segments:N,cpositions:v,dpositions:_}=await U[k];y+=L.fetchedSize(),c?.(y,b);let G=L.minv.dataPosition;if(w){if(Vt(N,(H,z)=>Ts(H,z,v,_,G,w)))return}else if(Vt(N,(H,z)=>{let S=0,J=0;for(;S<H.length;){let M=H.indexOf(qe,S);if(M===-1)break;let Y=S+z+G;for(;J<_.length&&Y>=_[J];)J++;if(u!==void 0&&H[S]===u){S=M+1;continue}f[0]=S-1;for(let X=0;X<p;X++){let T=f[X],O=T<M?H.indexOf(tn,T+1):-1;f[X+1]=O===-1||O>=M?M:O}let K=f[B-1]+1,W=f[B]-K;if(W!==x.length){S=M+1;continue}let eA=!0;for(let X=0;X<W;X++)if(H[K+X]!==x[X]){eA=!1;break}if(!eA){S=M+1;continue}let tA=Oe(H,f[E-1]+1,f[E])+m;if(tA>=l)return!0;let V;if(d===0||d===E?V=tA+1:I?V=Us(H,tA,f[3]+1,f[4],f[d-1]+1,f[d],f[5]):V=Oe(H,f[d-1]+1,f[d]),V>g){let X=H[M-1]===Si?M-1:M,T=D.decode(H.subarray(S,X));s(T,vi(v,_,J,S+z,G),tA,V)}S=M+1}return!1}))return;R=Math.min(R*2,_s),h(k+1+R)}}async getMetadata(e={}){return this.index.getMetadata(e)}async readHeaderBytes(e){let{firstDataLine:A,maxBlockSize:n}=await this.getMetadata(e);if(A?.blockPosition===0&&A.dataPosition===0)return new Uint8Array(0);let r=(A?.blockPosition??0)+n,i=await this.filehandle.read(r,0,e);return se(i)}async parseHeader(e){let{metaChar:A,skipLines:n=0}=await this.getMetadata(e),r=await this.readHeaderBytes(e);return{header:Fi.decode(A?Di(r,A):r),skippedLines:n>0?Ks(r,n):[]}}getParsedHeader(e={}){return this.headerCache.get("header",e.signal,A=>this.parseHeader({...e,signal:A}))}async getHeaderBuffer(e={}){let{metaChar:A}=await this.getMetadata(e),n=await this.readHeaderBytes(e);return A?Di(n,A):n}async getSkippedLines(e={}){let{skipLines:A=0}=await this.getMetadata(e);return A<=0?[]:(await this.getParsedHeader(e)).skippedLines}async getHeader(e={}){return(await this.getParsedHeader(e)).header}async getHeaderLines(e={}){let{header:A,skippedLines:n}=await this.getParsedHeader(e);return(A?A.split(/\r?\n/):n).filter(Boolean)}async getReferenceSequenceNames(e={}){return(await this.getMetadata(e)).refIdToName}async lineCount(e,A={}){return this.index.lineCount(e,A)}async readChunk(e,A={}){let n=await this.filehandle.read(e.fetchedSize(),e.minv.blockPosition,A);FA(A.signal);let r=await this.bgzfWorkerPool;return Pt(n,e,r)}};var Os=t=>({type:"fileLocation",defaultValue:{uri:t,locationType:"UriLocation"}}),Bc=(t,e="")=>rn(t,{indexType:{model:on.enumeration("IndexType",["TBI","CSI"]),type:"stringEnum",defaultValue:"TBI"},location:Os(e)});function qs(t,e,A){return{indexType:A?"CSI":"TBI",location:{uri:`${t}.${A?"csi":"tbi"}`,baseUri:e}}}function Ec(t){let{walksUri:e,baseUri:A,csi:n}=t;if(typeof e!="string")return t;let r=`${e}.walks.bed.gz`;return{...t,walksLocation:{uri:r,baseUri:A},walksIndex:qs(r,A,n)}}function dc(t,e,A){let n=t.pluginManager;return new zA({filehandle:sn(t.getConf(e),n),...an(t.getConf([...A,"location"]),t.getConf([...A,"indexType"]),n)})}function Zs(t){return`${t.assemblyName} ${t.refName} is not in this graph's index; a graph with PanSN names (GRCh38#0#chr1) needs ${t.assemblyName} mapped to its prefix in assemblyNameToPanSN`}var Ri=class{constructor(e,A){this.file=e;this.adapter=A;this.lookup=cn({setup:async e=>WA(await this.names(e))})}async names(e){return(await this.file.getReferenceSequenceNames(e)).filter(n=>!n.includes("~"))}async assemblyRefNames(e={}){let A=await this.names(e),n=ge(this.adapter,e.assemblyName),r=A.filter(i=>Ze(i,n)).map(i=>nn(i));return r.length>0?[...new Set(r)]:A}async resolve(e,A){let n=await this.lookup(A);return VA(n,ge(this.adapter,e.assemblyName),e.refName)}async resolveMapped(e,A){let n=await this.resolve(e,A);if(n===void 0&&e.assemblyName){let r=await this.names(A),i=ge(this.adapter,e.assemblyName);if(r.every(o=>o.includes("#"))&&!r.some(o=>Ze(o,i)))throw new Error(Zs(e))}return n}async resolveForCut(e,A){let n=await this.resolveMapped(e,A);if(n===void 0)throw new Error(`This graph has nothing on ${e.assemblyName} ${e.refName}`);return n}async regionBytes(e,A={},n=async(r,i)=>i.start){let r=[];for(let i of e){let o=await this.resolve(i,A);o!==void 0&&r.push({refName:o,start:await n(o,i),end:i.end})}return rr(this.file,r,A)}};export{se as a,Ps as b,cn as c,aA as d,Pe as e,UA as f,NA as g,Yi as h,At as i,Xi as j,gt as k,Be as l,sA as m,Ee as n,so as o,qn as p,co as q,Io as r,de as s,Eo as t,lt as u,uo as v,Et as w,dt as x,No as y,Sa as z,Os as A,Bc as B,qs as C,Ec as D,dc as E,Ri as F};
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