jbrowse-plugin-graphgenomeviewer 7.1.0 → 7.1.2

package/dist/chunks/chunk-FHZXW7IG.js

@@ -0,0 +1,2 @@
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Map,r=C=>{C&&i.set(`${C.refName}:${C.start}`,C)},a=(C,E,d)=>{let{ids:k}=C,u=E+d;for(;u>=0&&u<k.length&&o(k[u])===void 0;)u+=d;if(u<0||u>=k.length)return r(d<0?C.prev:C.next),u-d;let B=o(k[E]),p=o(k[u]);return p.refName!==A?u-d:u===E+d&&(p.start===B.end||p.end===B.start)?E:u},Q=1/0,s=-1/0,g=[];for(let C of t){let{ids:E}=C,d=-1,k=-1;for(let u=0;u<E.length;u++)n(E[u])&&(d<0&&(d=u),k=u);if(d>=0){if(C.name!==A){d=a(C,d,-1),k=a(C,k,1);for(let u of[d,k]){let B=o(E[u]);B&&(Q=Math.min(Q,B.start),s=Math.max(s,B.end))}}g.push({run:C,first:d,last:k})}}let l=C=>{let E=o(C);return n(C)||E?.refName===A&&E.end>Q&&E.start<s},f=new Set;for(let[C,E]of e)E.onWindow&&f.add(C);for(let C of g){let{ids:E}=C.run;if(C.run.name===A){for(;C.first>0&&l(E[C.first-1]);)C.first--;for(;C.last<E.length-1&&l(E[C.last+1]);)C.last++}for(let d=C.first;d<=C.last;d++)f.add(E[d])}let I=C=>{let E=e.get(C);return E===void 0?0:E.end-E.start},c=[];for(let{run:C,first:E,last:d}of 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k=this.referenceFirst(A),u=new Int32Array(k.length+1);k.forEach(({ids:w},h)=>{u[h+1]=u[h]+w.length});let B=new Int32Array(u[k.length]),p=new Uint8Array(B.length);return k.forEach(({ids:w,rev:h},N)=>{let m=u[N];for(let D=0;D<w.length;D++)B[m+D]=f(w[D]);p.set(h,m)}),{nodes:{names:i,lengths:Q,refs:s,starts:g,ranks:l,refNames:r},links:{from:C,to:E,strands:d},walks:{names:k.map(w=>w.name),starts:Float64Array.from(k,w=>w.hapStart),ends:Float64Array.from(k,w=>w.hapEnd),offsets:u,steps:B,reversed:p}}}referenceFirst(e){let{refName:A}=this.window;return[...e].sort((n,o)=>+(o.name===A)-+(n.name===A)||(n.name<o.name?-1:n.name>o.name?1:n.hapStart-o.hapStart))}},Ne={steps:"the step budget",bytes:"a byte budget of"};function me(t,e,A,n,o,i,r=Ne){var a;let Q=0,s=new Map,g=new Set;for(let E of t)Q+=E.n,s.set(E.chunkStart,((a=s.get(E.chunkStart))!==null&&a!==void 0?a:0)+E.n),g.add(E.name);let l=e*A;if(Q<=l)return;let f=n.end-n.start,I=0,c=0;for(let E 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dA=15,Kt=852,qt=592,Tt=0,Le=1,Zt=2,ki=[3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0],pi=[16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78],Di=[1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0],Ni=[16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64];function gA(t,e,A,n,o,i,r,a){var Q=a.bits,s=0,g=0,l=0,f=0,I=0,c=0,C=0,E=0,d=0,k=0,u,B,p,w,h,N=null,m=0,D,y=AA(dA+1),x=AA(dA+1),S=null,b=0,L,G,J;for(s=0;s<=dA;s++)y[s]=0;for(g=0;g<n;g++)y[e[A+g]]++;for(I=Q,f=dA;f>=1&&y[f]===0;f--);if(I>f&&(I=f),f===0)return 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$n(t,e){return t*2**e}function rt(t,e){return Math.floor(t/2**e)}var EA=class extends CA{async _parse(e={}){let{bytes:A,dataView:n}=await this.readIndexBytes(e),o=n.getUint32(0,!0),i;if(o===ao)i=1;else if(o===go)i=2;else throw new Error(`Not a CSI file (magic=${o})`);let r=n.getInt32(4,!0),a=n.getInt32(8,!0),Q=(8**(a+1)-1)/7,s=2**(r+a*3),g=n.getInt32(12,!0),l=g>=28&&(n.getInt32(16,!0)&15)===3;if(g<30&&!l)throw new Error("CSI index has no tabix header, so it names no references; it may be a BAM or BCF index");let f=Ie(A,16),I=n.getInt32(16+g,!0),c=16+g+4,C,E=[];for(let k=0;k<I;k++){E.push(c);let u=n.getInt32(c,!0);c+=4;for(let B=0;B<u;B++){let p=n.getUint32(c,!0);if(c+=4,p>Q)c+=44;else{C=ge(A,c,1,C),c+=8;let w=n.getInt32(c,!0);c+=4+16*w}}}function d(k){let u=E[k];if(u===void 0)return;let B=u,p=n.getInt32(B,!0);B+=4;let w={},h={},N;for(let m=0;m<p;m++){let D=n.getUint32(B,!0);if(B+=4,D>Q)N=Qe(A,B+28),B+=44;else{h[D]=nA(A,B),B+=8;let y=n.getInt32(B,!0);B+=4;let x=Array.from({length:y});for(let S=0;S<y;S++)x[S]=new Z(nA(A,B),nA(A,B+8),D),B+=16;w[D]=x}}return ae(Object.values(w).flat()),{binIndex:w,loffsets:h,stats:N}}return{...f,csi:!0,refCount:I,maxBlockSize:65536,firstDataLine:C,csiVersion:i,indices:Be(d),minShift:r,depth:a,maxBinNumber:Q,maxRefLength:s}}lowestOffset(e,A,{minShift:n,depth:o}){let{loffsets:i}=e,r;if(i){let a=($n(1,3*o)-1)/7+rt(Math.max(A,0),n);for(;r===void 0&&a>0;)if(r=i[a],r===void 0){let Q=Math.floor((a-1)/8),s=Q*8+1;a=a>s?a-1:Q}r??=i[0]}return r}reg2bins(e,A,{minShift:n,depth:o,maxBinNumber:i}){e=Math.max(e,0);let r=2**(n+o*3);A>r&&(A=r),A-=1;let a=0,Q=0,s=n+o*3,g=[];for(;a<=o;s-=3,Q+=$n(1,a*3),a+=1){let l=Q+rt(e,s),f=Q+rt(A,s);if(f-l+g.length>i)throw new Error(`query ${e}-${A} is too large for current binning scheme (shift ${n}, depth ${o}), try a smaller query or a coarser index binning scheme`);g.push([l,f])}return g}};var Io=21578324,st=5,at=14,Ce=2**(at+st*3);function Ai(t){return Math.min(Math.max(t,0),Ce)}var 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url")}function lo({tbiFilehandle:t,csiFilehandle:e,tbiPath:A,csiPath:n,tbiUrl:o,csiUrl:i,path:r,url:a}){if(t)return new V({filehandle:t});if(e)return new EA({filehandle:e});if(A)return new V({filehandle:new BA(A)});if(n)return new EA({filehandle:new BA(n)});if(i)return new EA({filehandle:new j(i)});if(o)return new V({filehandle:new j(o)});if(r)return new V({filehandle:new BA(`${r}.tbi`)});if(a)return new V({filehandle:new j(`${a}.tbi`)});throw new TypeError("must provide one of tbiFilehandle, tbiPath, csiFilehandle, csiPath, tbiUrl, csiUrl")}function ii(t,e,A,n,o){return t[A]*256+(n-e[A])+o+1}function uo(t,e,A,n,o,i,r){let a=n-A,Q=e+a,s=0;if(t[o]===46)return Q;let g=o;for(let l=o;l<=i;l++)if(l===i||t[l]===Qo){let f=l-g;if(f>=10&&t[g]===83&&t[g+1]===86&&t[g+2]===84&&t[g+3]===89&&t[g+4]===80&&t[g+5]===69&&t[g+6]===61&&t[g+7]===84&&t[g+8]===82&&t[g+9]===65)return e+1;if(f>=4&&t[g]===69&&t[g+1]===78&&t[g+2]===68&&t[g+3]===61){let I=Ee(t,g+4,l);I>e&&(Q=I)}else 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i=t[o];if(i>=48&&i<=57)n=n*10+(i-48);else break}return n}function Do(t,e,A,n,{start:o,end:i,pathCol:r,metaCharCode:a,decoder:Q,callback:s}){let g=0,l=0;for(;g<t.length;){let f=t.indexOf(ce,g);if(f===-1)break;let I=g;g=f+1;let c=I+n;for(;l<A.length&&c>=A[l];)l++;if(t[I]===a)continue;let C=I;for(let p=1;p<r;p++){let w=t.indexOf(gt,C);if(w===-1||w>=f){C=f;break}C=w+1}let E=t[C];if(E!==Co&&E!==Bo)continue;let d=t.indexOf(gt,C);(d===-1||d>f)&&(d=f);let k=1/0,u=-1,B=C;for(;B<d;){let p=0,w=B+1;for(;w<d;w++){let h=t[w]-48;if(h<0||h>9)break;p=p*10+h}p<k&&(k=p),p>u&&(u=p),B=w}if(k>=i)return!0;if(u>=o){let p=t[f-1]===ni?f-1:f;s(Q.decode(t.subarray(I,p)),ii(e,A,l,I,n),k,u+1)}}return!1}var pA=class{filehandle;index;chunkCache;headerCache=new tA({});bgzfWorkerPool;constructor({path:e,filehandle:A,url:n,tbiPath:o,tbiUrl:i,tbiFilehandle:r,csiPath:a,csiUrl:Q,csiFilehandle:s,chunkCacheSize:g=co,chunkCacheIdleTimeoutMs:l=fo,chunkCacheBudget:f,bgzfWorkerPool:I}){this.bgzfWorkerPool=I,this.filehandle=ho(A,e,n),this.index=lo({tbiFilehandle:r,csiFilehandle:s,tbiPath:o,csiPath:a,tbiUrl:i,csiUrl:Q,path:e,url:n}),this.chunkCache=new tA({maxSize:g,sizeOf:c=>c.buffer.byteLength,cacheKey:c=>c.toString(),idleTimeoutMs:l,budget:f,fill:(c,C)=>this.readChunk(c,{signal:C})})}clearChunkCache(){this.chunkCache.clear()}async bytesForRegions(e,A={}){let n=[];for(let{refName:i,start:r,end:a}of e){let Q=await this.index.blocksForRange(i,r,a,A);for(let s of Q)n.push(s)}let o=0;for(let i of se(n))o+=i.fetchedSize();return o}async getLines(e,A,n,o){let i,r={},a,Q;typeof o=="function"?a=o:(r=o,a=o.lineCallback,i=o.signal,Q=o.onProgress);let s=await this.index.getMetadata(r),g=A??0,l=n??s.maxRefLength;if(g>l)throw new TypeError("invalid start and end coordinates. start must be less than or equal to end");if(g===l)return;let f=await this.index.blocksForRange(e,g,l,r),I=s.format==="VCF",c=s.columnNumbers.ref||0,C=s.columnNumbers.start||0,E=I?8:s.columnNumbers.end||0,d=Math.max(c,C,E),k=s.metaChar?.charCodeAt(0),u=s.coordinateType==="1-based-closed"?-1:0,B=new TextEncoder,p=new TextDecoder,w=B.encode(e),h=new Int32Array(d+1),N=s.format==="GAF"?{start:g,end:l,pathCol:C,metaCharCode:k,decoder:p,callback:a}:void 0,m=0;for(let b of f)m+=b.fetchedSize();let D=0;Q?.(0,m);let y=1,x=[],S=b=>{for(;x.length<Math.min(b,f.length);){let L=f[x.length],G=this.chunkCache.get(L,i);G.catch(()=>{}),x.push(G)}};S(1);for(let b=0,L=f.length;b<L;b++){let G=f[b],{buffer:J,cpositions:iA,dpositions:O}=await x[b];D+=G.fetchedSize(),Q?.(D,m);let oA=G.minv.dataPosition;if(N){if(Do(J,iA,O,oA,N))return}else{let R=0,cA=0;for(;R<J.length;){let H=J.indexOf(ce,R);if(H===-1)break;let si=R+oA;for(;cA<O.length&&si>=O[cA];)cA++;if(k!==void 0&&J[R]===k){R=H+1;continue}h[0]=R-1;for(let K=0;K<d;K++){let YA=h[K],fe=YA<H?J.indexOf(gt,YA+1):-1;h[K+1]=fe===-1||fe>=H?H:fe}let It=h[c-1]+1,Qt=h[c]-It;if(Qt!==w.length){R=H+1;continue}let Bt=!0;for(let K=0;K<Qt;K++)if(J[It+K]!==w[K]){Bt=!1;break}if(!Bt){R=H+1;continue}let UA=Ee(J,h[C-1]+1,h[C])+u;if(UA>=l)return;let DA;if(E===0||E===C?DA=UA+1:I?DA=uo(J,UA,h[3]+1,h[4],h[E-1]+1,h[E],h[5]):DA=Ee(J,h[E-1]+1,h[E]),DA>g){let K=J[H-1]===ni?H-1:H,YA=p.decode(J.subarray(R,K));a(YA,ii(iA,O,cA,R,oA),UA,DA)}R=H+1}}y=Math.min(y*2,Eo),S(b+1+y)}}async getMetadata(e={}){return this.index.getMetadata(e)}async readHeaderBytes(e){let{firstDataLine:A,maxBlockSize:n}=await this.getMetadata(e),o=(A?.blockPosition??0)+n,i=await this.filehandle.read(o,0,e);return LA(i)}async parseHeader(e){let{metaChar:A,skipLines:n=0}=await this.getMetadata(e),o=await this.readHeaderBytes(e);return{header:oi.decode(A?ti(o,A):o),skippedLines:n>0?po(o,n):[]}}getParsedHeader(e={}){return this.headerCache.get("header",e.signal,A=>this.parseHeader({...e,signal:A}))}async getHeaderBuffer(e={}){let{metaChar:A}=await this.getMetadata(e),n=await this.readHeaderBytes(e);return A?ti(n,A):n}async getSkippedLines(e={}){let{skipLines:A=0}=await this.getMetadata(e);return A<=0?[]:(await this.getParsedHeader(e)).skippedLines}async getHeader(e={}){return(await this.getParsedHeader(e)).header}async getHeaderLines(e={}){let{header:A,skippedLines:n}=await this.getParsedHeader(e);return(A?A.split(/\r?\n/):n).filter(Boolean)}async getReferenceSequenceNames(e={}){return(await this.getMetadata(e)).refIdToName}async lineCount(e,A={}){return this.index.lineCount(e,A)}async readChunk(e,A={}){let n=await this.filehandle.read(e.fetchedSize(),e.minv.blockPosition,A),o=await this.bgzfWorkerPool;return At(n,e,o)}};var No=50*2**20,mo=t=>({type:"fileLocation",defaultValue:{uri:t,locationType:"UriLocation"}}),Ss=(t,e="")=>ct(t,{indexType:{model:ft.enumeration("IndexType",["TBI","CSI"]),type:"stringEnum",defaultValue:"TBI"},location:mo(e)});function yo(t,e,A){return{indexType:A?"CSI":"TBI",location:{uri:`${t}.${A?"csi":"tbi"}`,baseUri:e}}}function Js(t){let{walksUri:e,baseUri:A,csi:n}=t;if(typeof e!="string")return t;let o=`${e}.walks.bed.gz`;return{...t,walksLocation:{uri:o,baseUri:A},walksIndex:yo(o,A,n)}}function vs(t,e,A){let n=t.pluginManager;return new pA({filehandle:ht(t.getConf(e),n),...lt(t.getConf([...A,"location"]),t.getConf([...A,"indexType"]),n),chunkCacheSize:No})}var ri=class{constructor(e,A){this.file=e;this.adapter=A;this.lookup=ut({setup:async e=>FA(await this.file.getReferenceSequenceNames(e))})}async assemblyRefNames(e={}){let A=await this.file.getReferenceSequenceNames(e),n=he(this.adapter,e.assemblyName),o=A.filter(i=>Et(i,n)).map(i=>Ct(i));return o.length>0?[...new Set(o)]:A}async resolve(e,A){let n=await this.lookup(A);return bA(n,he(this.adapter,e.assemblyName),e.refName)}async regionBytes(e,A={},n=async o=>o){let o=[];for(let i of e){let r=await this.resolve(i,A);r!==void 0&&o.push({refName:r,start:await n(i.start),end:i.end})}return Jt(this.file,o,A)}};export{LA as a,Fo as b,ut as c,Ii as d,Qi as e,hi as f,be as g,Po as h,mo as i,Ss as j,yo as k,Js as l,vs as m,ri as n};
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