igv 3.8.2 → 3.8.4

package/dist/igv.esm.js

@@ -8820,6 +8820,8 @@ class IGVXhr {
         if (isFile(url)) {
             return this._loadFileSlice(url, options)
         } else if (isString$3(url)) {
+            // Convert "virtual" URLs (keys that don't exist) to real URLs before any other action
+            url = await convert(url);
             if (url.startsWith("data:")) {
                 const buffer = decodeDataURI$1(url).buffer;
                 if (options.range) {
@@ -9326,6 +9328,34 @@ function getGlobalObject() {
     }
 }
 
+let mappings;
+
+const mappingURL = "https://raw.githubusercontent.com/igvteam/igv-data/refs/heads/main/data/url_mappings.tsv";
+
+async function convert(url) {
+
+    if (!mappings) {
+        mappings = new Map();
+
+        try {
+            const data = await igvxhr.loadString(mappingURL);
+            const lines = data.split("\n");
+            for (const line of lines) {
+                if (line.startsWith("#")) continue
+
+                const tokens = line.split('\t');
+                if (tokens.length === 2) {
+                    mappings.set(tokens[0], tokens[1]);
+                }
+            }
+        } catch (e) {
+            console.error(`Error loading url mappings`, e);
+        }
+    }
+
+    return mappings.has(url) ? mappings.get(url) : url
+}
+
 
 const igvxhr = new IGVXhr();
 
@@ -10606,7 +10636,7 @@ function didSelectSingleTrackType(types) {
     return 1 === unique.length
 }
 
-/*! @license DOMPurify 3.4.10 | (c) Cure53 and other contributors | Released under the Apache license 2.0 and Mozilla Public License 2.0 | github.com/cure53/DOMPurify/blob/3.4.10/LICENSE */
+/*! @license DOMPurify 3.4.11 | (c) Cure53 and other contributors | Released under the Apache license 2.0 and Mozilla Public License 2.0 | github.com/cure53/DOMPurify/blob/3.4.11/LICENSE */
 
 function _arrayLikeToArray(r, a) {
   (null == a || a > r.length) && (a = r.length);
@@ -10943,7 +10973,6 @@ const COMMENT_MARKUP_PROBE = seal(/<[/\w]/g);
 const FALLBACK_TAG_CLOSE = seal(/<\/no(script|embed|frames)/i);
 const SELF_CLOSING_TAG = seal(/\/>/i);
 
-/* eslint-disable @typescript-eslint/indent */
 // https://developer.mozilla.org/en-US/docs/Web/API/Node/nodeType
 const NODE_TYPE = {
   element: 1,
@@ -11033,7 +11062,7 @@ const _resolveSetOption = function _resolveSetOption(cfg, key, fallback, options
 function createDOMPurify() {
   let window = arguments.length > 0 && arguments[0] !== undefined ? arguments[0] : getGlobal();
   const DOMPurify = root => createDOMPurify(root);
-  DOMPurify.version = '3.4.10';
+  DOMPurify.version = '3.4.11';
   DOMPurify.removed = [];
   if (!window || !window.document || window.document.nodeType !== NODE_TYPE.document || !window.Element) {
     // Not running in a browser, provide a factory function
@@ -11222,6 +11251,13 @@ function createDOMPurify() {
   let WHOLE_DOCUMENT = false;
   /* Track whether config is already set on this instance of DOMPurify. */
   let SET_CONFIG = false;
+  /* Pristine allowlist bindings captured at setConfig() time. On the
+   * persistent-config path sanitize() restores the sets from these before
+   * the per-walk hook clone-guard, so a hook's in-call widening cannot
+   * carry across calls. Null until setConfig() is called; reset by
+   * clearConfig(). */
+  let SET_CONFIG_ALLOWED_TAGS = null;
+  let SET_CONFIG_ALLOWED_ATTR = null;
   /* Decide if all elements (e.g. style, script) must be children of
    * document.body. By default, browsers might move them to document.head */
   let FORCE_BODY = false;
@@ -11531,21 +11567,6 @@ function createDOMPurify() {
         emptyHTML = _createTrustedHTML('');
       }
     }
-    /*
-     * Mirror the clone-before-mutate pattern already applied above for
-     * cfg.ADD_TAGS / cfg.ADD_ATTR: if any uponSanitize* hook is
-     * registered AND the set still points at the default constant,
-     * clone it. The hook then mutates the clone (in-call widening
-     * still works exactly as documented) and the next default-cfg
-     * call rebinds to the untouched original via the reassignment at
-     * the top of this function.
-     */
-    if ((hooks.uponSanitizeElement.length > 0 || hooks.uponSanitizeAttribute.length > 0) && ALLOWED_TAGS === DEFAULT_ALLOWED_TAGS) {
-      ALLOWED_TAGS = clone(ALLOWED_TAGS);
-    }
-    if (hooks.uponSanitizeAttribute.length > 0 && ALLOWED_ATTR === DEFAULT_ALLOWED_ATTR) {
-      ALLOWED_ATTR = clone(ALLOWED_ATTR);
-    }
     // Prevent further manipulation of configuration.
     // Not available in IE8, Safari 5, etc.
     if (freeze) {
@@ -12602,9 +12623,31 @@ function createDOMPurify() {
       return dirty;
     }
     /* Assign config vars */
-    if (!SET_CONFIG) {
+    if (SET_CONFIG) {
+      /* Persistent setConfig() path: _parseConfig is skipped, so the sets are
+       * not re-derived per call. Restore them from the pristine bindings
+       * captured at setConfig() time so a previous call's hook clone (mutated
+       * below) does not carry over. */
+      ALLOWED_TAGS = SET_CONFIG_ALLOWED_TAGS;
+      ALLOWED_ATTR = SET_CONFIG_ALLOWED_ATTR;
+    } else {
       _parseConfig(cfg);
     }
+    /* Clone the hook-mutable allowlists before the walk whenever an
+     * uponSanitize* hook is registered. The hook event exposes ALLOWED_TAGS
+     * and ALLOWED_ATTR by reference (as allowedTags / allowedAttributes), so
+     * a hook that widens them would otherwise mutate the shared set
+     * permanently: across later calls and across every element. Cloning per
+     * walk keeps documented in-call widening working while scoping it to the
+     * call. A single guard for both config paths - the per-call path rebinds
+     * the sets in _parseConfig each call, the persistent path restores them
+     * from the captured bindings just above - so the two cannot diverge. */
+    if (hooks.uponSanitizeElement.length > 0 || hooks.uponSanitizeAttribute.length > 0) {
+      ALLOWED_TAGS = clone(ALLOWED_TAGS);
+    }
+    if (hooks.uponSanitizeAttribute.length > 0) {
+      ALLOWED_ATTR = clone(ALLOWED_ATTR);
+    }
     /* Clean up removed elements */
     DOMPurify.removed = [];
     /* Resolve IN_PLACE for this call without mutating persistent config.
@@ -12780,10 +12823,14 @@ function createDOMPurify() {
     let cfg = arguments.length > 0 && arguments[0] !== undefined ? arguments[0] : {};
     _parseConfig(cfg);
     SET_CONFIG = true;
+    SET_CONFIG_ALLOWED_TAGS = ALLOWED_TAGS;
+    SET_CONFIG_ALLOWED_ATTR = ALLOWED_ATTR;
   };
   DOMPurify.clearConfig = function () {
     CONFIG = null;
     SET_CONFIG = false;
+    SET_CONFIG_ALLOWED_TAGS = null;
+    SET_CONFIG_ALLOWED_ATTR = null;
     // Drop any caller-supplied Trusted Types policy so it cannot poison later
     // `RETURN_TRUSTED_TYPE` output. The internal default policy (cached, and
     // never recreated — Trusted Types throws on duplicate names) is restored by
@@ -12804,9 +12851,19 @@ function createDOMPurify() {
     if (typeof hookFunction !== 'function') {
       return;
     }
+    /* Reject unknown entry points. Without this, a non-hook key (e.g.
+     * '__proto__') indexes off the prototype chain rather than a real
+     * hook array, and arrayPush then writes to Object.prototype. Guard
+     * with an own-property check against the known hook names. */
+    if (!objectHasOwnProperty(hooks, entryPoint)) {
+      return;
+    }
     arrayPush(hooks[entryPoint], hookFunction);
   };
   DOMPurify.removeHook = function (entryPoint, hookFunction) {
+    if (!objectHasOwnProperty(hooks, entryPoint)) {
+      return undefined;
+    }
     if (hookFunction !== undefined) {
       const index = arrayLastIndexOf(hooks[entryPoint], hookFunction);
       return index === -1 ? undefined : arraySplice(hooks[entryPoint], index, 1)[0];
@@ -12814,6 +12871,9 @@ function createDOMPurify() {
     return arrayPop(hooks[entryPoint]);
   };
   DOMPurify.removeHooks = function (entryPoint) {
+    if (!objectHasOwnProperty(hooks, entryPoint)) {
+      return;
+    }
     hooks[entryPoint] = [];
   };
   DOMPurify.removeAllHooks = function () {
@@ -40060,7 +40120,7 @@ class TrackDbHub {
      */
     #getTrackConfig(t) {
 
-        const format = typeFormatMap.get(t.format) || t.format;
+        const format = typeFormatMap.get(t.format.toLowerCase()) || t.format;
 
         const config = {
             "id": t.getProperty("track"),
@@ -40159,14 +40219,9 @@ class TrackDbHub {
             config.visibilityWindow = maxWindowToDraw;
         }
 
-        // IGV does not support "maxWindowCoverage" in the same way as UCSC. Use to limit visibility window
-        if (t.hasProperty("maxWindowCoverage")) {
-            let maxWindowToDraw = parseInt(t.getProperty("maxWindowCoverage"), 10);
-            if (maxWindowToDraw > Number.MAX_SAFE_INTEGER) {
-                maxWindowToDraw = Number.MAX_SAFE_INTEGER;
-            }
-            config.visibilityWindow = maxWindowToDraw;
-        }
+        // TODO - support "maxWindowCoverage"
+        // if (t.hasProperty("maxWindowCoverage")) {
+        // }
 
         return config
     }
@@ -51119,7 +51174,9 @@ class BamAlignment {
         nameValues.push('<hr/>');
         nameValues.push({name: 'Genomic Location: ', value: numberFormatter$1(1 + genomicLocation)});
         nameValues.push({name: 'Read Base:', value: readBase});
-        nameValues.push({name: 'Base Quality:', value: this.readBaseQualityAt(genomicLocation)});
+
+        let quality = this.readBaseQualityAt(genomicLocation);
+        nameValues.push({name: 'Base Quality:', value: 255 === quality ? "unknown" : quality});
 
         const bmSets = this.getBaseModificationSets();
         if (bmSets) {
@@ -51170,13 +51227,13 @@ class BamAlignment {
         const block = this.blockAtGenomicLocation(genomicLocation);
         if (block) {
             if ("*" === this.qual) {
-                return 30
+                return undefined
             } else {
                 const idx = block.seqIndexAt(genomicLocation);
                 if (idx >= 0 && this.qual && idx < this.qual.length) {
                     return this.qual[idx]
                 } else {
-                    return 30
+                    return undefined
                 }
             }
         } else {
@@ -52522,7 +52579,9 @@ class HtsgetBamReader extends HtsgetReader {
 }
 
 /*! For license information please see cram-bundle.js.LICENSE.txt */
-var gmodCRAM = (()=>{var e={24:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.toHex=function(e){let t="";for(let r=0,i=e.length;r<i;r++)t+=n[e[r]];return t};const r=["0","1","2","3","4","5","6","7","8","9","A","B","C","D","E","F"],n=new Array(256);for(let e=0;e<256;e++)n[e]=`${r[e>>>4&15]}${r[15&e]}`;},78:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0});const n=r(24),i=[0,1,3,7,15,31,63,127,255];t.default=class{constructor(e){this.stream=e,this.bitOffset=0,this.curByte=0,this.hasByte=!1;}_ensureByte(){this.hasByte||(this.curByte=this.stream.readByte(),this.hasByte=!0);}read(e){let t=0;for(;e>0;){this._ensureByte();const r=8-this.bitOffset;if(e>=r)t<<=r,t|=i[r]&this.curByte,this.hasByte=!1,this.bitOffset=0,e-=r;else {t<<=e;const n=r-e;t|=(this.curByte&i[e]<<n)>>n,this.bitOffset+=e,e=0;}}return t}seek(e){const t=e%8,r=(e-t)/8;this.bitOffset=t,this.stream.seek(r),this.hasByte=!1;}pi(){const e=new Uint8Array(6);for(let t=0;t<e.length;t++)e[t]=this.read(8);return (0, n.toHex)(e)}};},86:(e,t,r)=>{const n=r(1308).A;e.exports=n,e.exports.default=n;},500:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=r(6272),a=r(6761),s=n(r(588)),A=n(r(9685)),o=n(r(7480)),c=r(7580),d=r(2549);function l(e,t,r,n){const a=!!(n.mate||void 0!==n.mateRecordNumber&&n.mateRecordNumber!==t);r.readName||(r.readName=String(r.uniqueId),n.readName=r.readName),r.mate={sequenceId:n.sequenceId,alignmentStart:n.alignmentStart,uniqueId:n.uniqueId},n.readName&&(r.mate.readName=n.readName),n.mate||void 0!==n.mateRecordNumber||(n.mate={sequenceId:r.sequenceId,alignmentStart:r.alignmentStart,uniqueId:r.uniqueId},r.readName&&(n.mate.readName=r.readName)),r.flags|=s.default.BAM_FPAIRED,n.flags&s.default.BAM_FUNMAP&&(r.flags|=s.default.BAM_FMUNMAP),r.flags&s.default.BAM_FUNMAP&&(n.flags|=s.default.BAM_FMUNMAP),n.flags&s.default.BAM_FREVERSE&&(r.flags|=s.default.BAM_FMREVERSE),r.flags&s.default.BAM_FREVERSE&&(n.flags|=s.default.BAM_FMREVERSE),void 0===r.templateLength&&(a?function(e,t,r){const n=function t(r){const n=[r];if(void 0!==r.mateRecordNumber&&r.mateRecordNumber>=0){const a=e[r.mateRecordNumber];if(!a)throw new i.CramMalformedError("intra-slice mate record not found, this file seems malformed");n.push(...t(a));}return n}(r),a=n.map((e=>e.alignmentStart)),s=n.map((e=>e.alignmentStart+e.readLength-1)),A=Math.max(...s)-Math.min(...a)+1;A>=0&&n.forEach((e=>{if(void 0!==e.templateLength)throw new i.CramMalformedError("mate pair group has some members that have template lengths already, this file seems malformed");e.templateLength=A;}));}(e,0,r):function(e,t){const r=Math.min(e.alignmentStart,t.alignmentStart),n=Math.max(e.alignmentStart+e.readLength-1,t.alignmentStart+t.readLength-1)-r+1;e.templateLength=n,t.templateLength=n;}(r,n)),r.mateRecordNumber=void 0;}class f{constructor(e,t,r){this.container=e,this.containerPosition=t,this.sliceSize=r,this.file=e.file;}async getHeader(){const{majorVersion:e}=await this.file.getDefinition(),t=(0, c.getSectionParsers)(e),r=await this.container.getHeader(),n=await this.file.readBlock(r._endPosition+this.containerPosition);if("MAPPED_SLICE_HEADER"===n.contentType){const e=(0, d.parseItem)(n.content,t.cramMappedSliceHeader.parser,0,r._endPosition);return {...n,parsedContent:e}}if("UNMAPPED_SLICE_HEADER"===n.contentType){const e=(0, d.parseItem)(n.content,t.cramUnmappedSliceHeader.parser,0,r._endPosition);return {...n,parsedContent:e}}throw new i.CramMalformedError(`error reading slice header block, invalid content type ${n.contentType}`)}async getBlocks(){const e=await this.getHeader();let t=e._endPosition;const r=new Array(e.parsedContent.numBlocks);for(let e=0;e<r.length;e++){const n=await this.file.readBlock(t);r[e]=n,t=r[e]._endPosition;}return r}async getCoreDataBlock(){return (await this.getBlocks())[0]}async _getBlocksContentIdIndex(){const e=await this.getBlocks(),t={};return e.forEach((e=>{"EXTERNAL_DATA"===e.contentType&&(t[e.contentId]=e);})),t}async getBlockByContentId(e){return (await this._getBlocksContentIdIndex())[e]}async getReferenceRegion(){const e=new TextDecoder("utf8"),t=(await this.getHeader()).parsedContent;if(!(0, c.isMappedSliceHeader)(t))throw new Error("slice header not mapped");if(t.refSeqId<0)return;const r=await this.container.getCompressionScheme();if(void 0===r)throw new Error("compression scheme undefined");if(t.refBaseBlockId>=0){const r=await this.getBlockByContentId(t.refBaseBlockId);if(!r)throw new i.CramMalformedError("embedded reference specified, but reference block does not exist");return {seq:e.decode(r.data),start:t.refSeqStart,end:t.refSeqStart+t.refSeqSpan-1,span:t.refSeqSpan}}if(r.referenceRequired||this.file.fetchReferenceSequenceCallback){if(!this.file.fetchReferenceSequenceCallback)throw new Error("reference sequence not embedded, and seqFetch callback not provided, cannot fetch reference sequence");const e=await this.file.fetchReferenceSequenceCallback(t.refSeqId,t.refSeqStart,t.refSeqStart+t.refSeqSpan-1);if(e.length!==t.refSeqSpan)throw new i.CramArgumentError("seqFetch callback returned a reference sequence of the wrong length");return {seq:e,start:t.refSeqStart,end:t.refSeqStart+t.refSeqSpan-1,span:t.refSeqSpan}}}getAllRecords(){return this.getRecords((()=>!0))}async _fetchRecords(){const{majorVersion:e}=await this.file.getDefinition(),t=await this.container.getCompressionScheme();if(void 0===t)throw new Error("compression scheme undefined");const r=await this.getHeader(),n=await this._getBlocksContentIdIndex();if(e>1&&this.file.options.checkSequenceMD5&&(0, c.isMappedSliceHeader)(r.parsedContent)&&r.parsedContent.refSeqId>=0&&"0000000000000000"!==r.parsedContent.md5?.join("")){const e=await this.getReferenceRegion();if(e){const{seq:t,start:n,end:a}=e,s=(0, d.sequenceMD5)(t),A=r.parsedContent.md5?.map((e=>(e<16?"0":"")+e.toString(16))).join("");if(s!==A)throw new i.CramMalformedError(`MD5 checksum reference mismatch for ref ${r.parsedContent.refSeqId} pos ${n}..${a}. recorded MD5: ${A}, calculated MD5: ${s}`)}}const s=await this.getCoreDataBlock(),f={lastAlignmentStart:(0, c.isMappedSliceHeader)(r.parsedContent)?r.parsedContent.refSeqStart:0,coreBlock:{bitPosition:7,bytePosition:0},externalBlocks:{map:new Map,getCursor(e){let t=this.map.get(e);return void 0===t&&(t={bitPosition:7,bytePosition:0},this.map.set(e,t)),t}}},u=e=>{const r=t.getCodecForDataSeries(e);if(!r)throw new i.CramMalformedError(`no codec defined for ${e} data series`);return r.decode(this,s,n,f)},g=new Array(r.parsedContent.numRecords);for(let i=0;i<g.length;i+=1)try{const a=(0,A.default)(this,u,t,r,s,n,f,e,i);g[i]=new o.default({...a,uniqueId:r.contentPosition+r.parsedContent.recordCounter+i+1});}catch(e){if(e instanceof a.CramBufferOverrunError){console.warn("read attempted beyond end of buffer, file seems truncated.");break}throw e}for(let e=0;e<g.length;e+=1){const t=g[e];if(t){const{mateRecordNumber:r}=t;void 0!==r&&r>=0&&g[r]&&l(g,e,t,g[r]);}}return g}async getRecords(e){const t=this.container.filePosition+this.containerPosition;let r=this.file.featureCache.get(t.toString());r||(r=this._fetchRecords(),this.file.featureCache.set(t.toString(),r));const n=(await r).filter(e);if(n.length&&this.file.fetchReferenceSequenceCallback){const e=await this.getHeader();if((0, c.isMappedSliceHeader)(e.parsedContent)&&(e.parsedContent.refSeqId>=0||-2===e.parsedContent.refSeqId)){const t=e.parsedContent.refSeqId>=0?e.parsedContent.refSeqId:void 0,r=await this.container.getCompressionScheme();if(void 0===r)throw new Error("compression scheme undefined");const i={};for(const e of n){const r=void 0!==t?t:e.sequenceId;let n=i[r];n||(n={id:r,start:e.alignmentStart,end:Number.NEGATIVE_INFINITY,seq:null},i[r]=n);const a=e.alignmentStart+(e.lengthOnRef||e.readLength)-1;a>n.end&&(n.end=a),e.alignmentStart<n.start&&(n.start=e.alignmentStart);}await Promise.all(Object.values(i).map((async e=>{-1!==e.id&&e.start<=e.end&&this.file.fetchReferenceSequenceCallback&&(e.seq=await this.file.fetchReferenceSequenceCallback(e.id,e.start,e.end));})));for(const e of n){const n=i[void 0!==t?t:e.sequenceId];if(n?.seq){const t=n.seq;e.addReferenceSequence({...n,seq:t},r);}}}}return n}}t.default=f,"getHeader getBlocks _getBlocksContentIdIndex".split(" ").forEach((e=>{(0, d.tinyMemoize)(f,e);}));},588:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default={CRAM_FLAG_PRESERVE_QUAL_SCORES:1,CRAM_FLAG_DETACHED:2,CRAM_FLAG_MATE_DOWNSTREAM:4,CRAM_FLAG_NO_SEQ:8,CRAM_FLAG_MASK:15,CRAM_M_REVERSE:1,CRAM_M_UNMAP:2,BAM_FPAIRED:1,BAM_FPROPER_PAIR:2,BAM_FUNMAP:4,BAM_FMUNMAP:8,BAM_FREVERSE:16,BAM_FMREVERSE:32,BAM_FREAD1:64,BAM_FREAD2:128,BAM_FSECONDARY:256,BAM_FQCFAIL:512,BAM_FDUP:1024,BAM_FSUPPLEMENTARY:2048,BAM_CMATCH:0,BAM_CINS:1,BAM_CDEL:2,BAM_CREF_SKIP:3,BAM_CSOFT_CLIP:4,BAM_CHARD_CLIP:5,BAM_CPAD:6,BAM_CEQUAL:7,BAM_CDIFF:8,BAM_CBACK:9,BAM_CIGAR_STR:"MIDNSHP:XB",BAM_CIGAR_SHIFT:4,BAM_CIGAR_MASK:15,BAM_CIGAR_TYPE:246183};},632:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(6761),s=r(6272);class A extends i.default{constructor(e,t){if(super(e,t),"int"!==this.dataType)throw new s.CramUnimplementedError(`${this.dataType} decoding not yet implemented by GAMMA codec`)}decode(e,t,r,n){let i=1;for(;0===(0, a.getBits)(t.content,n.coreBlock,1);)i+=1;return ((0, a.getBits)(t.content,n.coreBlock,i-1)|1<<i-1)-this.parameters.offset}}t.default=A;},652:e=>{function t(e){return !!e.constructor&&"function"==typeof e.constructor.isBuffer&&e.constructor.isBuffer(e)}e.exports=function(e){return null!=e&&(t(e)||function(e){return "function"==typeof e.readFloatLE&&"function"==typeof e.slice&&t(e.slice(0,0))}(e)||!!e._isBuffer)};},772:()=>{},807:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(6761),s=r(6272);class A extends i.default{constructor(e,t){if(super(e,t),"int"!==this.dataType)throw new s.CramUnimplementedError(`${this.dataType} decoding not yet implemented by BETA codec`)}decode(e,t,r,n){return (0, a.getBits)(t.content,n.coreBlock,this.parameters.length)-this.parameters.offset}}t.default=A;},870:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.decode=function(e,t,r){const n=f(e),i=u(t),a=new l(n,i);for(;!("eof"in n)||!n.eof();)if(a._init_block())a._read_bunzip();else {const e=a.reader.read(32)>>>0;if(e!==a.streamCRC&&d(o.DATA_ERROR,"Bad stream CRC (got "+a.streamCRC.toString(16)+" expected "+e.toString(16)+")"),!r||!("eof"in n)||n.eof())break;a._start_bunzip(n,i);}if("getBuffer"in i)return i.getBuffer()};const i=n(r(78)),a=n(r(8761)),s=n(r(6612)),A=function(e,t){const r=e[t];for(let r=t;r>0;r--)e[r]=e[r-1];return e[0]=r,r},o={OK:0,LAST_BLOCK:-1,NOT_BZIP_DATA:-2,UNEXPECTED_INPUT_EOF:-3,UNEXPECTED_OUTPUT_EOF:-4,DATA_ERROR:-5,OUT_OF_MEMORY:-6,OBSOLETE_INPUT:-7,END_OF_BLOCK:-8},c={};c[o.LAST_BLOCK]="Bad file checksum",c[o.NOT_BZIP_DATA]="Not bzip data",c[o.UNEXPECTED_INPUT_EOF]="Unexpected input EOF",c[o.UNEXPECTED_OUTPUT_EOF]="Unexpected output EOF",c[o.DATA_ERROR]="Data error",c[o.OUT_OF_MEMORY]="Out of memory",c[o.OBSOLETE_INPUT]="Obsolete (pre 0.9.5) bzip format not supported.";const d=function(e,t){let r=c[e]||"unknown error";t&&(r+=": "+t);const n=new TypeError(r);throw n.errorCode=e,n};class l{constructor(e,t){this.writePos=this.writeCurrent=this.writeCount=0,this._start_bunzip(e,t);}_init_block(){return this._get_next_block()?(this.blockCRC=new a.default,!0):(this.writeCount=-1,!1)}_start_bunzip(e,t){const r=new Uint8Array(4);4===e.read(r,0,4)&&"BZh"===String.fromCharCode(r[0],r[1],r[2])||d(o.NOT_BZIP_DATA,"bad magic");const n=r[3]-48;(n<1||n>9)&&d(o.NOT_BZIP_DATA,"level out of range"),this.reader=new i.default(e),this.dbufSize=1e5*n,this.nextoutput=0,this.outputStream=t,this.streamCRC=0;}_get_next_block(){let e,t,r;const n=this.reader,i=n.pi();if("177245385090"===i)return !1;"314159265359"!==i&&d(o.NOT_BZIP_DATA),this.targetBlockCRC=n.read(32)>>>0,this.streamCRC=(this.targetBlockCRC^(this.streamCRC<<1|this.streamCRC>>>31))>>>0,n.read(1)&&d(o.OBSOLETE_INPUT);const a=n.read(24);a>this.dbufSize&&d(o.DATA_ERROR,"initial position out of bounds");let s=n.read(16),c=new Uint8Array(256),l=0;for(e=0;e<16;e++)if(s&1<<15-e){const i=16*e;for(r=n.read(16),t=0;t<16;t++)r&1<<15-t&&(c[l++]=i+t);}const f=n.read(3);(f<2||f>6)&&d(o.DATA_ERROR);const u=n.read(15);0===u&&d(o.DATA_ERROR);const g=new Uint8Array(256);for(e=0;e<f;e++)g[e]=e;const h=new Uint8Array(u);for(e=0;e<u;e++){for(t=0;n.read(1);t++)t>=f&&d(o.DATA_ERROR);h[e]=A(g,t);}let C,I=l+2,_=[];for(t=0;t<f;t++){const t=new Uint8Array(I),r=new Uint16Array(21);for(s=n.read(5),e=0;e<I;e++){for(;(s<1||s>20)&&d(o.DATA_ERROR),n.read(1);)n.read(1)?s--:s++;t[e]=s;}var m,B;for(m=B=t[0],e=1;e<I;e++)t[e]>B?B=t[e]:t[e]<m&&(m=t[e]);C={},_.push(C),C.permute=new Uint16Array(258),C.limit=new Uint32Array(22),C.base=new Uint32Array(21),C.minLen=m,C.maxLen=B;let i=0;for(e=m;e<=B;e++)for(r[e]=C.limit[e]=0,s=0;s<I;s++)t[s]===e&&(C.permute[i++]=s);for(e=0;e<I;e++)r[t[e]]++;for(i=s=0,e=m;e<B;e++)i+=r[e],C.limit[e]=i-1,i<<=1,s+=r[e],C.base[e+1]=i-s;C.limit[B+1]=Number.MAX_VALUE,C.limit[B]=i+r[B]-1,C.base[m]=0;}const p=new Uint32Array(256);for(e=0;e<256;e++)g[e]=e;let w,E=0,Q=0,y=0;const b=this.dbuf=new Uint32Array(this.dbufSize);for(I=0;;){for(I--||(I=49,y>=u&&d(o.DATA_ERROR),C=_[h[y++]]),e=C.minLen,t=n.read(e);e>C.maxLen&&d(o.DATA_ERROR),!(t<=C.limit[e]);e++)t=t<<1|n.read(1);t-=C.base[e],(t<0||t>=258)&&d(o.DATA_ERROR);const r=C.permute[t];if(0!==r&&1!==r){if(E)for(E=0,Q+s>this.dbufSize&&d(o.DATA_ERROR),w=c[g[0]],p[w]+=s;s--;)b[Q++]=w;if(r>l)break;Q>=this.dbufSize&&d(o.DATA_ERROR),e=r-1,w=A(g,e),w=c[w],p[w]++,b[Q++]=w;}else E||(E=1,s=0),s+=0===r?E:2*E,E<<=1;}for((a<0||a>=Q)&&d(o.DATA_ERROR),t=0,e=0;e<256;e++)r=t+p[e],p[e]=t,t=r;for(e=0;e<Q;e++)w=255&b[e],b[p[w]]|=e<<8,p[w]++;let D=0,S=0,k=0;return Q&&(D=b[a],S=255&D,D>>=8,k=-1),this.writePos=D,this.writeCurrent=S,this.writeCount=Q,this.writeRun=k,!0}_read_bunzip(e,t){let r,n,i;if(this.writeCount<0)return 0;let a=this.dbuf,s=this.writePos,A=this.writeCurrent,c=this.writeCount,l=(this.outputsize,this.writeRun);for(;c;){for(c--,n=A,s=a[s],A=255&s,s>>=8,3===l++?(r=A,i=n,A=-1):(r=1,i=A),this.blockCRC.updateCRCRun(i,r);r--;)this.outputStream.writeByte(i),this.nextoutput++;A!=n&&(l=0);}return this.writeCount=c,this.blockCRC.getCRC()!==this.targetBlockCRC&&d(o.DATA_ERROR,"Bad block CRC (got "+this.blockCRC.getCRC().toString(16)+" expected "+this.targetBlockCRC.toString(16)+")"),this.nextoutput}}const f=function(e){if("readByte"in e)return e;const t=new s.default;return t.pos=0,t.readByte=function(){return e[this.pos++]},t.seek=function(e){this.pos=e;},t.eof=function(){return this.pos>=e.length},t},u=function(e){const t=new s.default;let r=!0;if(e)if("number"==typeof e)t.buffer=new Uint8Array(e),r=!1;else {if("writeByte"in e)return e;t.buffer=e,r=!1;}else t.buffer=new Uint8Array(16384);return t.pos=0,t.writeByte=function(e){if(r&&this.pos>=this.buffer.length){const e=new Uint8Array(2*this.buffer.length);e.set(this.buffer),this.buffer=e;}this.buffer[this.pos++]=e;},t.getBuffer=function(){if(this.pos!==this.buffer.length){if(!r)throw new TypeError("outputsize does not match decoded input");const e=new Uint8Array(this.pos);e.set(this.buffer.slice(0,this.pos)),this.buffer=e;}return this.buffer},t._coerced=!0,t};t.default=l;},1064:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(e){this.blob=e,this.size=e.size;}async read(e,t=0){if(!e)return new Uint8Array(0);const r=t,n=r+e;return new Uint8Array(await this.blob.slice(r,n).arrayBuffer())}async readFile(e){const t="string"==typeof e?e:e?.encoding;if("utf8"===t)return this.blob.text();if(t)throw new Error(`unsupported encoding: ${t}`);return new Uint8Array(await this.blob.arrayBuffer())}async stat(){return {size:this.size}}async close(){}};},1307:function(e,t,r){var n;n=e=>(()=>{var 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e;C--,_+=f[g++]<<m,m+=8;}_>>>=v,m-=v,r.back+=v;}if(_>>>=D,m-=D,r.back+=D,r.length=k,0===S){r.mode=26;break}if(32&S){r.back=-1,r.mode=c;break}if(64&S){e.msg="invalid literal/length code",r.mode=d;break}r.extra=15&S,r.mode=22;case 22:if(r.extra){for(L=r.extra;m<L;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}r.length+=_&(1<<r.extra)-1,_>>>=r.extra,m-=r.extra,r.back+=r.extra;}r.was=r.length,r.mode=23;case 23:for(;S=(O=r.distcode[_&(1<<r.distbits)-1])>>>16&255,k=65535&O,!((D=O>>>24)<=m);){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}if(!(240&S)){for(v=D,R=S,F=k;S=(O=r.distcode[F+((_&(1<<v+R)-1)>>v)])>>>16&255,k=65535&O,!(v+(D=O>>>24)<=m);){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}_>>>=v,m-=v,r.back+=v;}if(_>>>=D,m-=D,r.back+=D,64&S){e.msg="invalid distance code",r.mode=d;break}r.offset=k,r.extra=15&S,r.mode=24;case 24:if(r.extra){for(L=r.extra;m<L;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}r.offset+=_&(1<<r.extra)-1,_>>>=r.extra,m-=r.extra,r.back+=r.extra;}if(r.offset>r.dmax){e.msg="invalid distance too far back",r.mode=d;break}r.mode=25;case 25:if(0===I)break e;if(Q=E-I,r.offset>Q){if((Q=r.offset-Q)>r.whave&&r.sane){e.msg="invalid distance too far back",r.mode=d;break}Q>r.wnext?(Q-=r.wnext,y=r.wsize-Q):y=r.wnext-Q,Q>r.length&&(Q=r.length),b=r.window;}else b=u,y=h-r.offset,Q=r.length;Q>I&&(Q=I),I-=Q,r.length-=Q;do{u[h++]=b[y++];}while(--Q);0===r.length&&(r.mode=21);break;case 26:if(0===I)break e;u[h++]=r.length,I--,r.mode=21;break;case 27:if(r.wrap){for(;m<32;){if(0===C)break e;C--,_|=f[g++]<<m,m+=8;}if(E-=I,e.total_out+=E,r.total+=E,E&&(e.adler=r.check=r.flags?a(r.check,u,E,h-E):i(r.check,u,E,h-E)),E=I,(r.flags?_:l(_))!==r.check){e.msg="incorrect data check",r.mode=d;break}_=0,m=0;}r.mode=28;case 28:if(r.wrap&&r.flags){for(;m<32;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}if(_!==(4294967295&r.total)){e.msg="incorrect length check",r.mode=d;break}_=0,m=0;}r.mode=29;case 29:N=1;break e;case d:N=-3;break e;case 31:return -4;default:return o}return e.next_out=h,e.avail_out=I,e.next_in=g,e.avail_in=C,r.hold=_,r.bits=m,(r.wsize||E!==e.avail_out&&r.mode<d&&(r.mode<27||4!==t))&&p(e,e.output,e.next_out,E-e.avail_out)?(r.mode=31,-4):(w-=e.avail_in,E-=e.avail_out,e.total_in+=w,e.total_out+=E,r.total+=E,r.wrap&&E&&(e.adler=r.check=r.flags?a(r.check,u,E,e.next_out-E):i(r.check,u,E,e.next_out-E)),e.data_type=r.bits+(r.last?64:0)+(r.mode===c?128:0)+(20===r.mode||15===r.mode?256:0),(0===w&&0===E||4===t)&&0===N&&(N=-5),N)},t.inflateEnd=function(e){if(!e||!e.state)return o;var t=e.state;return t.window&&(t.window=null),e.state=null,0},t.inflateGetHeader=function(e,t){var r;return e&&e.state&&2&(r=e.state).wrap?(r.head=t,t.done=!1,0):o},t.inflateSetDictionary=function(e,t){var r,n=t.length;return e&&e.state?0!==(r=e.state).wrap&&11!==r.mode?o:11===r.mode&&i(1,t,n,0)!==r.check?-3:p(e,t,n,n)?(r.mode=31,-4):(r.havedict=1,0):o},t.inflateInfo="pako inflate (from Nodeca project)";},1492:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(6761),s=r(6272);class A extends i.default{constructor(e,t){if(super(e,t),"int"!==this.dataType)throw new s.CramUnimplementedError(`${this.dataType} decoding not yet implemented by SUBEXP codec`)}decode(e,t,r,n){let i,s,A=0;for(;(0, a.getBits)(t.content,n.coreBlock,1);)A+=1;return 0===A?(i=this.parameters.K,s=(0, a.getBits)(t.content,n.coreBlock,i)):(i=A+this.parameters.K-1,s=1<<i|(0, a.getBits)(t.content,n.coreBlock,i)),s-this.parameters.offset}}t.default=A;},1558:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.default=function(e,t,r,n){let A=e.getInt(),o=e.getInt(),c=e.getInt(),d=e.getInt();const l=n.remaining(),f=-4&l;for(let i=0;i<f;i+=4){const l=t.R[s.default.get(A,a.TF_SHIFT)],f=t.R[s.default.get(o,a.TF_SHIFT)],u=t.R[s.default.get(c,a.TF_SHIFT)],g=t.R[s.default.get(d,a.TF_SHIFT)];n.putAt(i,l),n.putAt(i+1,f),n.putAt(i+2,u),n.putAt(i+3,g),A=s.default.advanceSymbolStep(A,r[255&l],a.TF_SHIFT),o=s.default.advanceSymbolStep(o,r[255&f],a.TF_SHIFT),c=s.default.advanceSymbolStep(c,r[255&u],a.TF_SHIFT),d=s.default.advanceSymbolStep(d,r[255&g],a.TF_SHIFT),A=s.default.renormalize(A,e),o=s.default.renormalize(o,e),c=s.default.renormalize(c,e),d=s.default.renormalize(d,e);}let u;switch(n.setPosition(f),3&l){case 0:break;case 1:u=t.R[s.default.get(A,a.TF_SHIFT)],s.default.advanceSymbol(A,e,r[255&u],a.TF_SHIFT),n.put(u);break;case 2:u=t.R[s.default.get(A,a.TF_SHIFT)],s.default.advanceSymbol(A,e,r[255&u],a.TF_SHIFT),n.put(u),u=t.R[s.default.get(o,a.TF_SHIFT)],s.default.advanceSymbol(o,e,r[255&u],a.TF_SHIFT),n.put(u);break;case 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i=n(r(807)),a=n(r(7934)),s=n(r(8006)),A=n(r(8930)),o=n(r(632)),c=n(r(4056)),d=n(r(1492)),l=r(6272),f={1:A.default,3:c.default,4:a.default,5:s.default,6:i.default,7:d.default,9:o.default};},1668:(e,t,r)=>{var n={};(0, r(9805).assign)(n,r(3303),r(7083),r(9681)),e.exports=n;},1739:function(e,t,r){var n,i=this&&this.__createBinding||(Object.create?function(e,t,r,n){void 0===n&&(n=r);var i=Object.getOwnPropertyDescriptor(t,r);i&&!("get"in i?!t.__esModule:i.writable||i.configurable)||(i={enumerable:!0,get:function(){return t[r]}}),Object.defineProperty(e,n,i);}:function(e,t,r,n){void 0===n&&(n=r),e[n]=t[r];}),a=this&&this.__setModuleDefault||(Object.create?function(e,t){Object.defineProperty(e,"default",{enumerable:!0,value:t});}:function(e,t){e.default=t;}),s=this&&this.__importStar||(n=function(e){return n=Object.getOwnPropertyNames||function(e){var t=[];for(var r in e)Object.prototype.hasOwnProperty.call(e,r)&&(t[t.length]=r);return t},n(e)},function(e){if(e&&e.__esModule)return e;var 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c.default,u=0,g=1,h=2,C=3,I=4,_=5,m=7,B=8,p=9,w=10,E=12;function Q(e,t){let r=e+"";for(;r.length<t;)r="0"+r;return r}function y(e,t,r,n){let i=e[0][u].ReadByte();const a=n-e[0][i].ReadUint32();if(i==_)return t[n]=t[a],r[n]=r[a],t[n];let s=1;t[n]="",r[n]=new Array(256);do{switch(i=e[s][u].ReadByte(),i){case h:r[n][s]=e[s][h].ReadChar();break;case g:r[n][s]=e[s][g].ReadString();break;case m:r[n][s]=e[s][m].ReadUint32();break;case C:var A=e[s][C].ReadUint32(),o=e[s][I].ReadByte();r[n][s]=Q(A,o);break;case B:r[n][s]=(0|r[a][s])+e[s][B].ReadByte();break;case p:A=(0|r[a][s])+e[s][p].ReadByte(),o=r[a][s].length,r[n][s]=Q(A,o);break;case w:r[n][s]=r[a][s];break;default:r[n][s]="";}t[n]+=r[n][s++];}while(i!=E);return t[n]}},1996:(e,t,r)=>{var n=r(9805),i=!0,a=!0;try{String.fromCharCode.apply(null,[0]);}catch(e){i=!1;}try{String.fromCharCode.apply(null,new Uint8Array(1));}catch(e){a=!1;}for(var s=new n.Buf8(256),A=0;A<256;A++)s[A]=A>=252?6:A>=248?5:A>=240?4:A>=224?3:A>=192?2:1;function o(e,t){if(t<65534&&(e.subarray&&a||!e.subarray&&i))return String.fromCharCode.apply(null,n.shrinkBuf(e,t));for(var r="",s=0;s<t;s++)r+=String.fromCharCode(e[s]);return r}s[254]=s[254]=1,t.string2buf=function(e){var t,r,i,a,s,A=e.length,o=0;for(a=0;a<A;a++)55296==(64512&(r=e.charCodeAt(a)))&&a+1<A&&56320==(64512&(i=e.charCodeAt(a+1)))&&(r=65536+(r-55296<<10)+(i-56320),a++),o+=r<128?1:r<2048?2:r<65536?3:4;for(t=new n.Buf8(o),s=0,a=0;s<o;a++)55296==(64512&(r=e.charCodeAt(a)))&&a+1<A&&56320==(64512&(i=e.charCodeAt(a+1)))&&(r=65536+(r-55296<<10)+(i-56320),a++),r<128?t[s++]=r:r<2048?(t[s++]=192|r>>>6,t[s++]=128|63&r):r<65536?(t[s++]=224|r>>>12,t[s++]=128|r>>>6&63,t[s++]=128|63&r):(t[s++]=240|r>>>18,t[s++]=128|r>>>12&63,t[s++]=128|r>>>6&63,t[s++]=128|63&r);return t},t.buf2binstring=function(e){return o(e,e.length)},t.binstring2buf=function(e){for(var t=new n.Buf8(e.length),r=0,i=t.length;r<i;r++)t[r]=e.charCodeAt(r);return t},t.buf2string=function(e,t){var r,n,i,a,A=t||e.length,c=new Array(2*A);for(n=0,r=0;r<A;)if((i=e[r++])<128)c[n++]=i;else if((a=s[i])>4)c[n++]=65533,r+=a-1;else {for(i&=2===a?31:3===a?15:7;a>1&&r<A;)i=i<<6|63&e[r++],a--;a>1?c[n++]=65533:i<65536?c[n++]=i:(i-=65536,c[n++]=55296|i>>10&1023,c[n++]=56320|1023&i);}return o(c,n)},t.utf8border=function(e,t){var r;for((t=t||e.length)>e.length&&(t=e.length),r=t-1;r>=0&&128==(192&e[r]);)r--;return r<0||0===r?t:r+s[e[r]]>t?r:t};},1998:(e,t,r)=>{var n=r(9805),i=[3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0],a=[16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78],s=[1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0],A=[16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64];e.exports=function(e,t,r,o,c,d,l,f){var u,g,h,C,I,_,m,B,p,w=f.bits,E=0,Q=0,y=0,b=0,D=0,S=0,k=0,v=0,R=0,F=0,M=null,N=0,x=new n.Buf16(16),L=new n.Buf16(16),O=null,T=0;for(E=0;E<=15;E++)x[E]=0;for(Q=0;Q<o;Q++)x[t[r+Q]]++;for(D=w,b=15;b>=1&&0===x[b];b--);if(D>b&&(D=b),0===b)return c[d++]=20971520,c[d++]=20971520,f.bits=1,0;for(y=1;y<b&&0===x[y];y++);for(D<y&&(D=y),v=1,E=1;E<=15;E++)if(v<<=1,(v-=x[E])<0)return -1;if(v>0&&(0===e||1!==b))return -1;for(L[1]=0,E=1;E<15;E++)L[E+1]=L[E]+x[E];for(Q=0;Q<o;Q++)0!==t[r+Q]&&(l[L[t[r+Q]]++]=Q);if(0===e?(M=O=l,_=19):1===e?(M=i,N-=257,O=a,T-=257,_=256):(M=s,O=A,_=-1),F=0,Q=0,E=y,I=d,S=D,k=0,h=-1,C=(R=1<<D)-1,1===e&&R>852||2===e&&R>592)return 1;for(;;){m=E-k,l[Q]<_?(B=0,p=l[Q]):l[Q]>_?(B=O[T+l[Q]],p=M[N+l[Q]]):(B=96,p=0),u=1<<E-k,y=g=1<<S;do{c[I+(F>>k)+(g-=u)]=m<<24|B<<16|p;}while(0!==g);for(u=1<<E-1;F&u;)u>>=1;if(0!==u?(F&=u-1,F+=u):F=0,Q++,0===--x[E]){if(E===b)break;E=t[r+l[Q]];}if(E>D&&(F&C)!==h){for(0===k&&(k=D),I+=y,v=1<<(S=E-k);S+k<b&&!((v-=x[S+k])<=0);)S++,v<<=1;if(R+=1<<S,1===e&&R>852||2===e&&R>592)return 1;c[h=F&C]=D<<24|S<<16|I-d;}}return 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n=0,i=0;for(;n+this.F[i]<=r;)n+=this.F[i++];t.RangeDecode(e,n,this.F[i],this.total_freq),this.F[i]+=16,this.total_freq+=16,this.total_freq>65519&&this.ModelRenormalise();const a=this.S[i];if(i>0&&this.F[i]>this.F[i-1]){let e=this.F[i];this.F[i]=this.F[i-1],this.F[i-1]=e,e=this.S[i],this.S[i]=this.S[i-1],this.S[i-1]=e;}return a}ModelRenormalise(){this.total_freq=0;for(let e=0;e<=this.max_sym;e++)this.F[e]-=Math.floor(this.F[e]/2),this.total_freq+=this.F[e];}ModelEncode(e,t,r){let n=0;for(var i=0;this.S[i]!=r;i++)n+=this.F[i];if(t.RangeEncode(e,n,this.F[i],this.total_freq),this.F[i]+=16,this.total_freq+=16,this.total_freq>65519&&this.ModelRenormalise(),r=this.S[i],i>0&&this.F[i]>this.F[i-1]){let e=this.F[i];this.F[i]=this.F[i-1],this.F[i-1]=e,e=this.S[i],this.S[i]=this.S[i-1],this.S[i-1]=e;}}};},2549:function(e,t,r){var n=this&&this.__importDefault||function(e){return 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t=this.options;t.raw&&t.windowBits>0?t.windowBits=-t.windowBits:t.gzip&&t.windowBits>0&&t.windowBits<16&&(t.windowBits+=16),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new A,this.strm.avail_out=0;var r=n.deflateInit2(this.strm,t.level,t.method,t.windowBits,t.memLevel,t.strategy);if(0!==r)throw new Error(s[r]);if(t.header&&n.deflateSetHeader(this.strm,t.header),t.dictionary){var d;if(d="string"==typeof t.dictionary?a.string2buf(t.dictionary):"[object ArrayBuffer]"===o.call(t.dictionary)?new Uint8Array(t.dictionary):t.dictionary,0!==(r=n.deflateSetDictionary(this.strm,d)))throw new Error(s[r]);this._dict_set=!0;}}function d(e,t){var r=new c(t);if(r.push(e,!0),r.err)throw r.msg||s[r.err];return r.result}c.prototype.push=function(e,t){var r,s,A=this.strm,c=this.options.chunkSize;if(this.ended)return !1;s=t===~~t?t:!0===t?4:0,"string"==typeof e?A.input=a.string2buf(e):"[object ArrayBuffer]"===o.call(e)?A.input=new 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n,i,a,s,A;n=r(3939),i=r(2151).utf8,a=r(652),s=r(2151).bin,(A=function(e,t){e.constructor==String?e=t&&"binary"===t.encoding?s.stringToBytes(e):i.stringToBytes(e):a(e)?e=Array.prototype.slice.call(e,0):Array.isArray(e)||e.constructor===Uint8Array||(e=e.toString());for(var r=n.bytesToWords(e),o=8*e.length,c=1732584193,d=-271733879,l=-1732584194,f=271733878,u=0;u<r.length;u++)r[u]=16711935&(r[u]<<8|r[u]>>>24)|4278255360&(r[u]<<24|r[u]>>>8);r[o>>>5]|=128<<o%32,r[14+(o+64>>>9<<4)]=o;var g=A._ff,h=A._gg,C=A._hh,I=A._ii;for(u=0;u<r.length;u+=16){var _=c,m=d,B=l,p=f;c=g(c,d,l,f,r[u+0],7,-680876936),f=g(f,c,d,l,r[u+1],12,-389564586),l=g(l,f,c,d,r[u+2],17,606105819),d=g(d,l,f,c,r[u+3],22,-1044525330),c=g(c,d,l,f,r[u+4],7,-176418897),f=g(f,c,d,l,r[u+5],12,1200080426),l=g(l,f,c,d,r[u+6],17,-1473231341),d=g(d,l,f,c,r[u+7],22,-45705983),c=g(c,d,l,f,r[u+8],7,1770035416),f=g(f,c,d,l,r[u+9],12,-1958414417),l=g(l,f,c,d,r[u+10],17,-42063),d=g(d,l,f,c,r[u+11],22,-1990404162),c=g(c,d,l,f,r[u+12],7,1804603682),f=g(f,c,d,l,r[u+13],12,-40341101),l=g(l,f,c,d,r[u+14],17,-1502002290),c=h(c,d=g(d,l,f,c,r[u+15],22,1236535329),l,f,r[u+1],5,-165796510),f=h(f,c,d,l,r[u+6],9,-1069501632),l=h(l,f,c,d,r[u+11],14,643717713),d=h(d,l,f,c,r[u+0],20,-373897302),c=h(c,d,l,f,r[u+5],5,-701558691),f=h(f,c,d,l,r[u+10],9,38016083),l=h(l,f,c,d,r[u+15],14,-660478335),d=h(d,l,f,c,r[u+4],20,-405537848),c=h(c,d,l,f,r[u+9],5,568446438),f=h(f,c,d,l,r[u+14],9,-1019803690),l=h(l,f,c,d,r[u+3],14,-187363961),d=h(d,l,f,c,r[u+8],20,1163531501),c=h(c,d,l,f,r[u+13],5,-1444681467),f=h(f,c,d,l,r[u+2],9,-51403784),l=h(l,f,c,d,r[u+7],14,1735328473),c=C(c,d=h(d,l,f,c,r[u+12],20,-1926607734),l,f,r[u+5],4,-378558),f=C(f,c,d,l,r[u+8],11,-2022574463),l=C(l,f,c,d,r[u+11],16,1839030562),d=C(d,l,f,c,r[u+14],23,-35309556),c=C(c,d,l,f,r[u+1],4,-1530992060),f=C(f,c,d,l,r[u+4],11,1272893353),l=C(l,f,c,d,r[u+7],16,-155497632),d=C(d,l,f,c,r[u+10],23,-1094730640),c=C(c,d,l,f,r[u+13],4,681279174),f=C(f,c,d,l,r[u+0],11,-358537222),l=C(l,f,c,d,r[u+3],16,-722521979),d=C(d,l,f,c,r[u+6],23,76029189),c=C(c,d,l,f,r[u+9],4,-640364487),f=C(f,c,d,l,r[u+12],11,-421815835),l=C(l,f,c,d,r[u+15],16,530742520),c=I(c,d=C(d,l,f,c,r[u+2],23,-995338651),l,f,r[u+0],6,-198630844),f=I(f,c,d,l,r[u+7],10,1126891415),l=I(l,f,c,d,r[u+14],15,-1416354905),d=I(d,l,f,c,r[u+5],21,-57434055),c=I(c,d,l,f,r[u+12],6,1700485571),f=I(f,c,d,l,r[u+3],10,-1894986606),l=I(l,f,c,d,r[u+10],15,-1051523),d=I(d,l,f,c,r[u+1],21,-2054922799),c=I(c,d,l,f,r[u+8],6,1873313359),f=I(f,c,d,l,r[u+15],10,-30611744),l=I(l,f,c,d,r[u+6],15,-1560198380),d=I(d,l,f,c,r[u+13],21,1309151649),c=I(c,d,l,f,r[u+4],6,-145523070),f=I(f,c,d,l,r[u+11],10,-1120210379),l=I(l,f,c,d,r[u+2],15,718787259),d=I(d,l,f,c,r[u+9],21,-343485551),c=c+_>>>0,d=d+m>>>0,l=l+B>>>0,f=f+p>>>0;}return n.endian([c,d,l,f])})._ff=function(e,t,r,n,i,a,s){var A=e+(t&r|~t&n)+(i>>>0)+s;return (A<<a|A>>>32-a)+t},A._gg=function(e,t,r,n,i,a,s){var A=e+(t&n|r&~n)+(i>>>0)+s;return (A<<a|A>>>32-a)+t},A._hh=function(e,t,r,n,i,a,s){var A=e+(t^r^n)+(i>>>0)+s;return (A<<a|A>>>32-a)+t},A._ii=function(e,t,r,n,i,a,s){var A=e+(r^(t|~n))+(i>>>0)+s;return (A<<a|A>>>32-a)+t},A._blocksize=16,A._digestsize=16,e.exports=function(e,t){if(null==e)throw new Error("Illegal argument "+e);var r=n.wordsToBytes(A(e,t));return t&&t.asBytes?r:t&&t.asString?s.bytesToString(r):n.bytesToHex(r)};},3665:(e,t,r)=>{var n=r(9805);function i(e){for(var t=e.length;--t>=0;)e[t]=0;}var a=[0,0,0,0,0,0,0,0,1,1,1,1,2,2,2,2,3,3,3,3,4,4,4,4,5,5,5,5,0],s=[0,0,0,0,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13],A=[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,3,7],o=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15],c=new Array(576);i(c);var d=new Array(60);i(d);var l=new Array(512);i(l);var f=new Array(256);i(f);var u=new 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t;for(t=0;t<286;t++)e.dyn_ltree[2*t]=0;for(t=0;t<30;t++)e.dyn_dtree[2*t]=0;for(t=0;t<19;t++)e.bl_tree[2*t]=0;e.dyn_ltree[512]=1,e.opt_len=e.static_len=0,e.last_lit=e.matches=0;}function D(e){e.bi_valid>8?p(e,e.bi_buf):e.bi_valid>0&&(e.pending_buf[e.pending++]=e.bi_buf),e.bi_buf=0,e.bi_valid=0;}function S(e,t,r,n){var i=2*t,a=2*r;return e[i]<e[a]||e[i]===e[a]&&n[t]<=n[r]}function k(e,t,r){for(var n=e.heap[r],i=r<<1;i<=e.heap_len&&(i<e.heap_len&&S(t,e.heap[i+1],e.heap[i],e.depth)&&i++,!S(t,n,e.heap[i],e.depth));)e.heap[r]=e.heap[i],r=i,i<<=1;e.heap[r]=n;}function v(e,t,r){var n,i,A,o,c=0;if(0!==e.last_lit)do{n=e.pending_buf[e.d_buf+2*c]<<8|e.pending_buf[e.d_buf+2*c+1],i=e.pending_buf[e.l_buf+c],c++,0===n?E(e,i,t):(E(e,(A=f[i])+256+1,t),0!==(o=a[A])&&w(e,i-=u[A],o),E(e,A=B(--n),r),0!==(o=s[A])&&w(e,n-=I[A],o));}while(c<e.last_lit);E(e,256,t);}function R(e,t){var r,n,i,a=t.dyn_tree,s=t.stat_desc.static_tree,A=t.stat_desc.has_stree,o=t.stat_desc.elems,c=-1;for(e.heap_len=0,e.heap_max=573,r=0;r<o;r++)0!==a[2*r]?(e.heap[++e.heap_len]=c=r,e.depth[r]=0):a[2*r+1]=0;for(;e.heap_len<2;)a[2*(i=e.heap[++e.heap_len]=c<2?++c:0)]=1,e.depth[i]=0,e.opt_len--,A&&(e.static_len-=s[2*i+1]);for(t.max_code=c,r=e.heap_len>>1;r>=1;r--)k(e,a,r);i=o;do{r=e.heap[1],e.heap[1]=e.heap[e.heap_len--],k(e,a,1),n=e.heap[1],e.heap[--e.heap_max]=r,e.heap[--e.heap_max]=n,a[2*i]=a[2*r]+a[2*n],e.depth[i]=(e.depth[r]>=e.depth[n]?e.depth[r]:e.depth[n])+1,a[2*r+1]=a[2*n+1]=i,e.heap[1]=i++,k(e,a,1);}while(e.heap_len>=2);e.heap[--e.heap_max]=e.heap[1],function(e,t){var r,n,i,a,s,A,o=t.dyn_tree,c=t.max_code,d=t.stat_desc.static_tree,l=t.stat_desc.has_stree,f=t.stat_desc.extra_bits,u=t.stat_desc.extra_base,g=t.stat_desc.max_length,h=0;for(a=0;a<=15;a++)e.bl_count[a]=0;for(o[2*e.heap[e.heap_max]+1]=0,r=e.heap_max+1;r<573;r++)(a=o[2*o[2*(n=e.heap[r])+1]+1]+1)>g&&(a=g,h++),o[2*n+1]=a,n>c||(e.bl_count[a]++,s=0,n>=u&&(s=f[n-u]),A=o[2*n],e.opt_len+=A*(a+s),l&&(e.static_len+=A*(d[2*n+1]+s)));if(0!==h){do{for(a=g-1;0===e.bl_count[a];)a--;e.bl_count[a]--,e.bl_count[a+1]+=2,e.bl_count[g]--,h-=2;}while(h>0);for(a=g;0!==a;a--)for(n=e.bl_count[a];0!==n;)(i=e.heap[--r])>c||(o[2*i+1]!==a&&(e.opt_len+=(a-o[2*i+1])*o[2*i],o[2*i+1]=a),n--);}}(e,t),y(a,c,e.bl_count);}function F(e,t,r){var n,i,a=-1,s=t[1],A=0,o=7,c=4;for(0===s&&(o=138,c=3),t[2*(r+1)+1]=65535,n=0;n<=r;n++)i=s,s=t[2*(n+1)+1],++A<o&&i===s||(A<c?e.bl_tree[2*i]+=A:0!==i?(i!==a&&e.bl_tree[2*i]++,e.bl_tree[32]++):A<=10?e.bl_tree[34]++:e.bl_tree[36]++,A=0,a=i,0===s?(o=138,c=3):i===s?(o=6,c=3):(o=7,c=4));}function M(e,t,r){var n,i,a=-1,s=t[1],A=0,o=7,c=4;for(0===s&&(o=138,c=3),n=0;n<=r;n++)if(i=s,s=t[2*(n+1)+1],!(++A<o&&i===s)){if(A<c)do{E(e,i,e.bl_tree);}while(0!==--A);else 0!==i?(i!==a&&(E(e,i,e.bl_tree),A--),E(e,16,e.bl_tree),w(e,A-3,2)):A<=10?(E(e,17,e.bl_tree),w(e,A-3,3)):(E(e,18,e.bl_tree),w(e,A-11,7));A=0,a=i,0===s?(o=138,c=3):i===s?(o=6,c=3):(o=7,c=4);}}i(I);var N=!1;function x(e,t,r,i){w(e,0+(i?1:0),3),function(e,t,r){D(e),p(e,r),p(e,~r),n.arraySet(e.pending_buf,e.window,t,r,e.pending),e.pending+=r;}(e,t,r);}t._tr_init=function(e){N||(function(){var e,t,r,n,i,o=new Array(16);for(r=0,n=0;n<28;n++)for(u[n]=r,e=0;e<1<<a[n];e++)f[r++]=n;for(f[r-1]=n,i=0,n=0;n<16;n++)for(I[n]=i,e=0;e<1<<s[n];e++)l[i++]=n;for(i>>=7;n<30;n++)for(I[n]=i<<7,e=0;e<1<<s[n]-7;e++)l[256+i++]=n;for(t=0;t<=15;t++)o[t]=0;for(e=0;e<=143;)c[2*e+1]=8,e++,o[8]++;for(;e<=255;)c[2*e+1]=9,e++,o[9]++;for(;e<=279;)c[2*e+1]=7,e++,o[7]++;for(;e<=287;)c[2*e+1]=8,e++,o[8]++;for(y(c,287,o),e=0;e<30;e++)d[2*e+1]=5,d[2*e]=Q(e,5);g=new _(c,a,257,286,15),h=new _(d,s,0,30,15),C=new _(new Array(0),A,0,19,7);}(),N=!0),e.l_desc=new m(e.dyn_ltree,g),e.d_desc=new m(e.dyn_dtree,h),e.bl_desc=new m(e.bl_tree,C),e.bi_buf=0,e.bi_valid=0,b(e);},t._tr_stored_block=x,t._tr_flush_block=function(e,t,r,n){var i,a,s=0;e.level>0?(2===e.strm.data_type&&(e.strm.data_type=function(e){var t,r=4093624447;for(t=0;t<=31;t++,r>>>=1)if(1&r&&0!==e.dyn_ltree[2*t])return 0;if(0!==e.dyn_ltree[18]||0!==e.dyn_ltree[20]||0!==e.dyn_ltree[26])return 1;for(t=32;t<256;t++)if(0!==e.dyn_ltree[2*t])return 1;return 0}(e)),R(e,e.l_desc),R(e,e.d_desc),s=function(e){var t;for(F(e,e.dyn_ltree,e.l_desc.max_code),F(e,e.dyn_dtree,e.d_desc.max_code),R(e,e.bl_desc),t=18;t>=3&&0===e.bl_tree[2*o[t]+1];t--);return e.opt_len+=3*(t+1)+5+5+4,t}(e),i=e.opt_len+3+7>>>3,(a=e.static_len+3+7>>>3)<=i&&(i=a)):i=a=r+5,r+4<=i&&-1!==t?x(e,t,r,n):4===e.strategy||a===i?(w(e,2+(n?1:0),3),v(e,c,d)):(w(e,4+(n?1:0),3),function(e,t,r,n){var i;for(w(e,t-257,5),w(e,r-1,5),w(e,n-4,4),i=0;i<n;i++)w(e,e.bl_tree[2*o[i]+1],3);M(e,e.dyn_ltree,t-1),M(e,e.dyn_dtree,r-1);}(e,e.l_desc.max_code+1,e.d_desc.max_code+1,s+1),v(e,e.dyn_ltree,e.dyn_dtree)),b(e),n&&D(e);},t._tr_tally=function(e,t,r){return e.pending_buf[e.d_buf+2*e.last_lit]=t>>>8&255,e.pending_buf[e.d_buf+2*e.last_lit+1]=255&t,e.pending_buf[e.l_buf+e.last_lit]=255&r,e.last_lit++,0===t?e.dyn_ltree[2*r]++:(e.matches++,t--,e.dyn_ltree[2*(f[r]+256+1)]++,e.dyn_dtree[2*B(t)]++),e.last_lit===e.lit_bufsize-1},t._tr_align=function(e){w(e,2,3),E(e,256,c),function(e){16===e.bi_valid?(p(e,e.bi_buf),e.bi_buf=0,e.bi_valid=0):e.bi_valid>=8&&(e.pending_buf[e.pending++]=255&e.bi_buf,e.bi_buf>>=8,e.bi_valid-=8);}(e);};},3939:e=>{var t,r;t="ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/",r={rotl:function(e,t){return e<<t|e>>>32-t},rotr:function(e,t){return e<<32-t|e>>>t},endian:function(e){if(e.constructor==Number)return 16711935&r.rotl(e,8)|4278255360&r.rotl(e,24);for(var t=0;t<e.length;t++)e[t]=r.endian(e[t]);return e},randomBytes:function(e){for(var t=[];e>0;e--)t.push(Math.floor(256*Math.random()));return t},bytesToWords:function(e){for(var t=[],r=0,n=0;r<e.length;r++,n+=8)t[n>>>5]|=e[r]<<24-n%32;return t},wordsToBytes:function(e){for(var t=[],r=0;r<32*e.length;r+=8)t.push(e[r>>>5]>>>24-r%32&255);return t},bytesToHex:function(e){for(var t=[],r=0;r<e.length;r++)t.push((e[r]>>>4).toString(16)),t.push((15&e[r]).toString(16));return t.join("")},hexToBytes:function(e){for(var t=[],r=0;r<e.length;r+=2)t.push(parseInt(e.substr(r,2),16));return t},bytesToBase64:function(e){for(var r=[],n=0;n<e.length;n+=3)for(var i=e[n]<<16|e[n+1]<<8|e[n+2],a=0;a<4;a++)8*n+6*a<=8*e.length?r.push(t.charAt(i>>>6*(3-a)&63)):r.push("=");return r.join("")},base64ToBytes:function(e){e=e.replace(/[^A-Z0-9+\/]/gi,"");for(var r=[],n=0,i=0;n<e.length;i=++n%4)0!=i&&r.push((t.indexOf(e.charAt(n-1))&Math.pow(2,-2*i+8)-1)<<2*i|t.indexOf(e.charAt(n))>>>6-2*i);return r}},e.exports=r;},4056:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(6761),s=r(6272);class A extends i.default{constructor(e,t){if(super(e,t),this.codes={},this.codeBook={},this.sortedCodes=[],this.sortedValuesByBitCode=[],this.sortedBitCodes=[],this.sortedBitLengthsByBitCode=[],this.bitCodeToValue=[],!["byte","int"].includes(this.dataType))throw new TypeError(`${this.dataType} decoding not yet implemented by HUFFMAN_INT codec`);this.buildCodeBook(),this.buildCodes(),this.buildCaches(),0===this.sortedCodes[0].bitLength&&(this._decode=this._decodeZeroLengthCode);}buildCodeBook(){let e=new Array(this.parameters.numCodes);for(let t=0;t<this.parameters.numCodes;t++)e[t]={symbol:this.parameters.symbols[t],bitLength:this.parameters.bitLengths[t]};e=e.sort(((e,t)=>e.bitLength-t.bitLength||e.symbol-t.symbol)),this.codeBook={},e.forEach((e=>{this.codeBook[e.bitLength]||(this.codeBook[e.bitLength]=[]),this.codeBook[e.bitLength].push(e.symbol);}));}buildCodes(){this.codes={};let e=0,t=-1;Object.entries(this.codeBook).forEach((([r,n])=>{const i=Number.parseInt(r,10);n.forEach((r=>{const n={bitLength:i,value:r,bitCode:0};t+=1;const a=i-e;if(t<<=a,n.bitCode=t,e+=a,function(e){let t=e-(e>>1)&1431655765;return t=(858993459&t)+(t>>2&858993459),16843009*(t+(t>>4)&252645135)>>24}(t)>i)throw new s.CramMalformedError("Symbol out of range");this.codes[r]=n;}));}));}buildCaches(){this.sortedCodes=Object.values(this.codes).sort(((e,t)=>e.bitLength-t.bitLength||e.bitCode-t.bitCode)),this.sortedValuesByBitCode=this.sortedCodes.map((e=>e.value)),this.sortedBitCodes=this.sortedCodes.map((e=>e.bitCode)),this.sortedBitLengthsByBitCode=this.sortedCodes.map((e=>e.bitLength));const e=Math.max(...this.sortedBitCodes);this.bitCodeToValue=new Array(e+1).fill(-1);for(let e=0;e<this.sortedBitCodes.length;e+=1)this.bitCodeToValue[this.sortedCodes[e].bitCode]=e;}decode(e,t,r,n){return this._decode(e,t,n.coreBlock)}_decodeZeroLengthCode(){return this.sortedCodes[0].value}_decode(e,t,r){const n=t.content;let i=0,A=0;for(let e=0;e<this.sortedCodes.length;e+=1){const t=this.sortedCodes[e].bitLength;A<<=t-i,A|=(0, a.getBits)(n,r,t-i),i=t;{const r=this.bitCodeToValue[A];if(r>-1&&this.sortedBitLengthsByBitCode[r]===t)return this.sortedValuesByBitCode[r];for(let r=e;this.sortedCodes[r+1].bitLength===t&&r<this.sortedCodes.length;r+=1)e+=1;}}throw new s.CramMalformedError("Huffman symbol not found.")}}t.default=A;},4141:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(e,t){this.parameters=e,this.dataType=t;}};},4442:e=>{e.exports=function(){this.input=null,this.next_in=0,this.avail_in=0,this.total_in=0,this.output=null,this.next_out=0,this.avail_out=0,this.total_out=0,this.msg="",this.state=null,this.data_type=2,this.adler=0;};},4562:function(e,t,r){var n,i=this&&this.__createBinding||(Object.create?function(e,t,r,n){void 0===n&&(n=r);var i=Object.getOwnPropertyDescriptor(t,r);i&&!("get"in i?!t.__esModule:i.writable||i.configurable)||(i={enumerable:!0,get:function(){return t[r]}}),Object.defineProperty(e,n,i);}:function(e,t,r,n){void 0===n&&(n=r),e[n]=t[r];}),a=this&&this.__setModuleDefault||(Object.create?function(e,t){Object.defineProperty(e,"default",{enumerable:!0,value:t});}:function(e,t){e.default=t;}),s=this&&this.__importStar||(n=function(e){return n=Object.getOwnPropertyNames||function(e){var t=[];for(var r in e)Object.prototype.hasOwnProperty.call(e,r)&&(t[t.length]=r);return t},n(e)},function(e){if(e&&e.__esModule)return e;var t={};if(null!=e)for(var r=n(e),s=0;s<r.length;s++)"default"!==r[s]&&i(t,e,r[s]);return a(t,e),t}),A=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.r4x8_uncompress=function(e){return d.decode(e)},t.r4x16_uncompress=function(e){return l.decode(e)},t.arith_uncompress=function(e){return (new o.default).decode(e)},t.fqzcomp_uncompress=function(e){return c.decode(e,[])},t.tok3_uncompress=function(e){const t=f.decode(e,0,"\0");return Uint8Array.from(Array.from(t).map((e=>e.charCodeAt(0))))};const 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Multiple carry"),this.carry=1);this.range<1<<24;)this.range*=256,this.RangeShiftLow(e);}RangeFinishEncode(e){for(let t=0;t<5;t++)this.RangeShiftLow(e);}};},4674:e=>{e.exports={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible version"};},4823:e=>{var t=function(){for(var e,t=[],r=0;r<256;r++){e=r;for(var n=0;n<8;n++)e=1&e?3988292384^e>>>1:e>>>1;t[r]=e;}return t}();e.exports=function(e,r,n,i){var a=t,s=i+n;e^=-1;for(var A=i;A<s;A++)e=e>>>8^a[255&(e^r[A])];return -1^e};},4997:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.default=t.CramRecord=void 0;var i=r(7480);Object.defineProperty(t,"CramRecord",{enumerable:!0,get:function(){return n(i).default}});var a=r(8751);Object.defineProperty(t,"default",{enumerable:!0,get:function(){return n(a).default}});},5011:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.parseHeaderText=function(e){const t=e.split(/\r?\n/),r=[];for(const e of t){const[t,...n]=e.split(/\t/);t&&r.push({tag:t.slice(1),data:n.map((e=>{const t=e.indexOf(":");return -1!==t?{tag:e.slice(0,t),value:e.slice(t+1)}:{tag:e,value:""}}))});}return r};},5159:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.IndexedCramFile=t.CraiIndex=t.CramFile=t.CramRecord=void 0;var i=r(4997);Object.defineProperty(t,"CramRecord",{enumerable:!0,get:function(){return i.CramRecord}}),Object.defineProperty(t,"CramFile",{enumerable:!0,get:function(){return n(i).default}});var a=r(6638);Object.defineProperty(t,"CraiIndex",{enumerable:!0,get:function(){return n(a).default}});var s=r(8223);Object.defineProperty(t,"IndexedCramFile",{enumerable:!0,get:function(){return n(s).default}});},6268:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.readStatsO0=function(e,t,r){let n=0,i=0,o=255&e.get();do{null==t.fc[o]&&(t.fc[o]=new s.default.FC),t.fc[o].F=255&e.get(),t.fc[o].F>=128&&(t.fc[o].F&=-129,t.fc[o].F=(127&t.fc[o].F)<<8|255&e.get()),t.fc[o].C=i,s.default.symbolInit(r[o],t.fc[o].C,t.fc[o].F),t.R||(t.R=new Array(a.TOTFREQ)),t.R.fill(o,i,i+t.fc[o].F),i+=t.fc[o].F,0===n&&o+1===(255&e.getByteAt(e.position()))?(o=255&e.get(),n=255&e.get()):0!==n?(n-=1,o+=1):o=255&e.get();}while(0!==o);A(i<a.TOTFREQ);},t.readStatsO1=function(e,t,r){let n=0,i=255&e.get();do{let o=0,c=0,d=255&e.get();null==t[i]&&(t[i]=new s.default.AriDecoder);do{null==t[i].fc[d]&&(t[i].fc[d]=new s.default.FC),t[i].fc[d].F=255&e.get(),t[i].fc[d].F>=128&&(t[i].fc[d].F&=-129,t[i].fc[d].F=(127&t[i].fc[d].F)<<8|255&e.get()),t[i].fc[d].C=c,0===t[i].fc[d].F&&(t[i].fc[d].F=a.TOTFREQ),null==r[i][d]&&(r[i][d]=new 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r{};},6612:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{readByte(){throw new Error("abstract method readByte() not implemented")}read(e,t,r){let n=0;for(;n<r;){const r=this.readByte();if(r<0)return 0===n?-1:n;e[t++]=r,n++;}return n}writeByte(e){throw new Error("abstract method readByte() not implemented")}seek(e){throw new Error("abstract method seek() not implemented")}write(e,t,r){let n;for(n=0;n<r;n++)this.writeByte(e[t++]);return r}flush(){}};},6638:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0});const n=r(6272),i=r(6727),a=r(2169);function s(e,t){const[r,n,i,a,s,A]=t,o=r;e[o]||(e[o]=[]),e[o].push({start:n,span:i,containerStart:a,sliceStart:s,sliceBytes:A});}t.default=class{constructor(e){this.filehandle=(0, i.open)(e.url,e.path,e.filehandle);}async parseIndex(){const e={},t=31===(r=await this.filehandle.readFile())[0]&&139===r[1]?(0, a.unzip)(r):r;var r;const i=new DataView(t.buffer);if(t.length>4&&21578050===i.getUint32(0,!0))throw new n.CramMalformedError("invalid .crai index file. note: file appears to be a .bai index. this is technically legal but please open a github issue if you need support");let A=[],o="";for(const r of t)if(r>=48&&r<=57||!o&&45===r)o+=String.fromCharCode(r);else if(9===r)A.push(Number.parseInt(o,10)),o="";else if(10===r)A.push(Number.parseInt(o,10)),o="",s(e,A),A=[];else if(13!==r&&32!==r)throw new n.CramMalformedError("invalid .crai index file");return o&&A.push(Number.parseInt(o,10)),6===A.length&&s(e,A),Object.entries(e).forEach((([t,r])=>{const n=r;e[t]=n.sort(((e,t)=>e.start-t.start||e.span-t.span));})),e}getIndex(){return this.parseIndexP||(this.parseIndexP=this.parseIndex().catch((e=>{throw this.parseIndexP=void 0,e}))),this.parseIndexP}async hasDataForReferenceSequence(e){return !!(await this.getIndex())[e]}async getEntriesForRange(e,t,r){const n=(await this.getIndex())[e];if(!n)return [];const i=e=>{const n=e.start,i=e.start+e.span;return n>r?-1:i<=t?1:0},a=[];for(const e of n)0===i(e)&&a.push(e);return a}};},6727:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.RemoteFile=t.LocalFile=void 0,t.open=function(e,t,r){if(r)return r;if(e)return new n.RemoteFile(e);if(t)return new n.LocalFile(t);throw new Error("no url, path, or filehandle provided, cannot open")};const n=r(8301);var i=r(8301);Object.defineProperty(t,"LocalFile",{enumerable:!0,get:function(){return i.LocalFile}}),Object.defineProperty(t,"RemoteFile",{enumerable:!0,get:function(){return i.RemoteFile}});},6761:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.CramBufferOverrunError=void 0,t.getBits=function(e,t,n){let i=0;if(t.bytePosition+(7-t.bitPosition+n)/8>e.length)throw new r("read error during decoding. the file seems to be truncated.");for(let r=n;r;r--)i<<=1,i|=e[t.bytePosition]>>t.bitPosition&1,t.bitPosition-=1,t.bitPosition<0&&(t.bytePosition+=1),t.bitPosition&=7;return i};class r extends 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this.onEnd(r),this.ended=!0,!1;f.next_out&&(0!==f.avail_out&&r!==s.Z_STREAM_END&&(0!==f.avail_in||A!==s.Z_FINISH&&A!==s.Z_SYNC_FLUSH)||("string"===this.options.to?(o=a.utf8border(f.output,f.next_out),c=f.next_out-o,l=a.buf2string(f.output,o),f.next_out=c,f.avail_out=u-c,c&&i.arraySet(f.output,f.output,o,c,0),this.onData(l)):this.onData(i.shrinkBuf(f.output,f.next_out)))),0===f.avail_in&&0===f.avail_out&&(h=!0);}while((f.avail_in>0||0===f.avail_out)&&r!==s.Z_STREAM_END);return r===s.Z_STREAM_END&&(A=s.Z_FINISH),A===s.Z_FINISH?(r=n.inflateEnd(this.strm),this.onEnd(r),this.ended=!0,r===s.Z_OK):A!==s.Z_SYNC_FLUSH||(this.onEnd(s.Z_OK),f.avail_out=0,!0)},l.prototype.onData=function(e){this.chunks.push(e);},l.prototype.onEnd=function(e){e===s.Z_OK&&("string"===this.options.to?this.result=this.chunks.join(""):this.result=i.flattenChunks(this.chunks)),this.chunks=[],this.err=e,this.msg=this.strm.msg;},t.Inflate=l,t.inflate=f,t.inflateRaw=function(e,t){return (t=t||{}).raw=!0,f(e,t)},t.ungzip=f;},7151:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.TOTFREQ=t.TF_SHIFT=t.RANS_BYTE_L=void 0,t.TF_SHIFT=12,t.TOTFREQ=4096,t.RANS_BYTE_L=1<<23;},7293:e=>{e.exports=function(e,t){var r,n,i,a,s,A,o,c,d,l,f,u,g,h,C,I,_,m,B,p,w,E,Q,y,b;r=e.state,n=e.next_in,y=e.input,i=n+(e.avail_in-5),a=e.next_out,b=e.output,s=a-(t-e.avail_out),A=a+(e.avail_out-257),o=r.dmax,c=r.wsize,d=r.whave,l=r.wnext,f=r.window,u=r.hold,g=r.bits,h=r.lencode,C=r.distcode,I=(1<<r.lenbits)-1,_=(1<<r.distbits)-1;e:do{g<15&&(u+=y[n++]<<g,g+=8,u+=y[n++]<<g,g+=8),m=h[u&I];t:for(;;){if(u>>>=B=m>>>24,g-=B,0==(B=m>>>16&255))b[a++]=65535&m;else {if(!(16&B)){if(64&B){if(32&B){r.mode=12;break e}e.msg="invalid literal/length code",r.mode=30;break e}m=h[(65535&m)+(u&(1<<B)-1)];continue t}for(p=65535&m,(B&=15)&&(g<B&&(u+=y[n++]<<g,g+=8),p+=u&(1<<B)-1,u>>>=B,g-=B),g<15&&(u+=y[n++]<<g,g+=8,u+=y[n++]<<g,g+=8),m=C[u&_];;){if(u>>>=B=m>>>24,g-=B,16&(B=m>>>16&255)){if(w=65535&m,g<(B&=15)&&(u+=y[n++]<<g,(g+=8)<B&&(u+=y[n++]<<g,g+=8)),(w+=u&(1<<B)-1)>o){e.msg="invalid distance too far back",r.mode=30;break e}if(u>>>=B,g-=B,w>(B=a-s)){if((B=w-B)>d&&r.sane){e.msg="invalid distance too far back",r.mode=30;break e}if(E=0,Q=f,0===l){if(E+=c-B,B<p){p-=B;do{b[a++]=f[E++];}while(--B);E=a-w,Q=b;}}else if(l<B){if(E+=c+l-B,(B-=l)<p){p-=B;do{b[a++]=f[E++];}while(--B);if(E=0,l<p){p-=B=l;do{b[a++]=f[E++];}while(--B);E=a-w,Q=b;}}}else if(E+=l-B,B<p){p-=B;do{b[a++]=f[E++];}while(--B);E=a-w,Q=b;}for(;p>2;)b[a++]=Q[E++],b[a++]=Q[E++],b[a++]=Q[E++],p-=3;p&&(b[a++]=Q[E++],p>1&&(b[a++]=Q[E++]));}else {E=a-w;do{b[a++]=b[E++],b[a++]=b[E++],b[a++]=b[E++],p-=3;}while(p>2);p&&(b[a++]=b[E++],p>1&&(b[a++]=b[E++]));}break}if(64&B){e.msg="invalid distance code",r.mode=30;break e}m=C[(65535&m)+(u&(1<<B)-1)];}}break}}while(n<i&&a<A);n-=p=g>>3,u&=(1<<(g-=p<<3))-1,e.next_in=n,e.next_out=a,e.avail_in=n<i?i-n+5:5-(n-i),e.avail_out=a<A?A-a+257:257-(a-A),r.hold=u,r.bits=g;};},7392:e=>{class t{constructor(e={}){if(!(e.maxSize&&e.maxSize>0))throw new TypeError("`maxSize` must be a number greater than 0");this.maxSize=e.maxSize,this.cache=new Map,this.oldCache=new Map,this._size=0;}_set(e,t){this.cache.set(e,t),this._size++,this._size>=this.maxSize&&(this._size=0,this.oldCache=this.cache,this.cache=new Map);}get(e){if(this.cache.has(e))return this.cache.get(e);if(this.oldCache.has(e)){const t=this.oldCache.get(e);return this.oldCache.delete(e),this._set(e,t),t}}set(e,t){return this.cache.has(e)?this.cache.set(e,t):this._set(e,t),this}has(e){return this.cache.has(e)||this.oldCache.has(e)}peek(e){return this.cache.has(e)?this.cache.get(e):this.oldCache.has(e)?this.oldCache.get(e):void 0}delete(e){const t=this.cache.delete(e);return t&&this._size--,this.oldCache.delete(e)||t}clear(){this.cache.clear(),this.oldCache.clear(),this._size=0;}*keys(){for(const[e]of this)yield e;}*values(){for(const[,e]of this)yield e;}*[Symbol.iterator](){for(const e of this.cache)yield e;for(const e of this.oldCache){const[t]=e;this.cache.has(t)||(yield e);}}get size(){let e=0;for(const t of this.oldCache.keys())this.cache.has(t)||e++;return this._size+e}}e.exports=t;},7414:e=>{e.exports=function(){this.text=0,this.time=0,this.xflags=0,this.os=0,this.extra=null,this.extra_len=0,this.name="",this.comment="",this.hcrc=0,this.done=!1;};},7480:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.MateFlagsDecoder=t.CramFlagsDecoder=t.BamFlagsDecoder=t.MateFlags=t.CramFlags=t.BamFlags=void 0;const i=n(r(588)),a={a:0,A:0,c:1,C:1,g:2,G:2,t:3,T:3,n:4,N:4};function s(e){const t={};for(const[r,n]of e)t[`is${n}`]=e=>!!(e&r),t[`set${n}`]=e=>e|r;return t}t.BamFlags=[[1,"Paired"],[2,"ProperlyPaired"],[4,"SegmentUnmapped"],[8,"MateUnmapped"],[16,"ReverseComplemented"],[32,"MateReverseComplemented"],[64,"Read1"],[128,"Read2"],[256,"Secondary"],[512,"FailedQc"],[1024,"Duplicate"],[2048,"Supplementary"]],t.CramFlags=[[1,"PreservingQualityScores"],[2,"Detached"],[4,"WithMateDownstream"],[8,"DecodeSequenceAsStar"]],t.MateFlags=[[1,"OnNegativeStrand"],[2,"Unmapped"]],t.BamFlagsDecoder=s(t.BamFlags),t.CramFlagsDecoder=s(t.CramFlags),t.MateFlagsDecoder=s(t.MateFlags),t.default=class{constructor({flags:e,cramFlags:t,readLength:r,mappingQuality:n,lengthOnRef:i,qualityScores:a,mateRecordNumber:s,readBases:A,readFeatures:o,mateToUse:c,readGroupId:d,readName:l,sequenceId:f,uniqueId:u,templateSize:g,alignmentStart:h,tags:C}){this.flags=e,this.cramFlags=t,this.readLength=r,this.mappingQuality=n,this.lengthOnRef=i,this.qualityScores=a,A&&(this.readBases=A),this.readGroupId=d,this.readName=l,this.sequenceId=f,this.uniqueId=u,this.templateSize=g,this.alignmentStart=h,this.tags=C,o&&(this.readFeatures=o),c&&(this.mate={flags:c.mateFlags,readName:c.mateReadName,sequenceId:c.mateSequenceId,alignmentStart:c.mateAlignmentStart}),s&&(this.mateRecordNumber=s);}isPaired(){return !!(this.flags&i.default.BAM_FPAIRED)}isProperlyPaired(){return !!(this.flags&i.default.BAM_FPROPER_PAIR)}isSegmentUnmapped(){return !!(this.flags&i.default.BAM_FUNMAP)}isMateUnmapped(){return !!(this.flags&i.default.BAM_FMUNMAP)}isReverseComplemented(){return !!(this.flags&i.default.BAM_FREVERSE)}isMateReverseComplemented(){return !!(this.flags&i.default.BAM_FMREVERSE)}isRead1(){return !!(this.flags&i.default.BAM_FREAD1)}isRead2(){return !!(this.flags&i.default.BAM_FREAD2)}isSecondary(){return !!(this.flags&i.default.BAM_FSECONDARY)}isFailedQc(){return !!(this.flags&i.default.BAM_FQCFAIL)}isDuplicate(){return !!(this.flags&i.default.BAM_FDUP)}isSupplementary(){return !!(this.flags&i.default.BAM_FSUPPLEMENTARY)}isDetached(){return !!(this.cramFlags&i.default.CRAM_FLAG_DETACHED)}hasMateDownStream(){return !!(this.cramFlags&i.default.CRAM_FLAG_MATE_DOWNSTREAM)}isPreservingQualityScores(){return !!(this.cramFlags&i.default.CRAM_FLAG_PRESERVE_QUAL_SCORES)}isUnknownBases(){return !!(this.cramFlags&i.default.CRAM_FLAG_NO_SEQ)}getReadBases(){if(!this.readBases&&this._refRegion){const e=function(e,t){if(!e.lengthOnRef&&!e.readLength)return null;if(e.isUnknownBases())return null;const r=e.alignmentStart-t.start;if(!e.readFeatures)return t.seq.slice(r,r+(e.lengthOnRef||0)).toUpperCase();let n="",i=r,a=0;for(;n.length<e.readLength;)if(a<e.readFeatures.length){const r=e.readFeatures[a];if("Q"===r.code||"q"===r.code)a+=1;else if(r.pos===n.length+1)if(a+=1,"b"===r.code){const e=r.data;n+=e,i+=e.length;}else "B"===r.code?(n+=r.data[0],i+=1):"X"===r.code?(n+=r.sub,i+=1):"I"===r.code?n+=r.data:"D"===r.code?i+=r.data:"i"===r.code?n+=r.data:"N"===r.code?i+=r.data:"S"===r.code?n+=r.data:"P"===r.code||r.code;else if(a<e.readFeatures.length){const e=t.seq.slice(i,i+r.pos-n.length-1);n+=e,i+=e.length;}}else {const r=t.seq.slice(i,i+e.readLength-n.length);n+=r,i+=r.length;}return n.toUpperCase()}(this,this._refRegion);e&&(this.readBases=e);}return this.readBases}getPairOrientation(){if(!this.isSegmentUnmapped()&&this.isPaired()&&!this.isMateUnmapped()&&this.mate&&this.sequenceId===this.mate.sequenceId){const e=this.isReverseComplemented()?"R":"F",t=this.isMateReverseComplemented()?"R":"F";let r=" ",n=" ";this.isRead1()?(r="1",n="2"):this.isRead2()&&(r="2",n="1");const i=[];let a=this.templateLength||this.templateSize;if(void 0===a)throw new Error("One of templateSize and templateLength must be set");return this.alignmentStart>this.mate.alignmentStart&&a>0&&(a=-a),a>0?(i[0]=e,i[1]=r,i[2]=t,i[3]=n):(i[2]=e,i[3]=r,i[0]=t,i[1]=n),i.join("")}return null}addReferenceSequence(e,t){this.readFeatures&&this.readFeatures.forEach((r=>{"X"===r.code&&function(e,t,r,n){const i=n.refPos-t.start,s=t.seq.charAt(i);s&&(n.ref=s);let A=a[s];void 0===A&&(A=4);const o=r.substitutionMatrix[A][n.data];o&&(n.sub=o);}(0,e,t,r);})),!this.readBases&&e.start<=this.alignmentStart&&e.end>=this.alignmentStart+(this.lengthOnRef||this.readLength)-1&&(this._refRegion=e);}toJSON(){const e={};return Object.keys(this).forEach((t=>{t.startsWith("_")||(e[t]=this[t]);})),e.readBases=this.getReadBases(),e}};},7580:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.cramFileDefinition=i,t.cramBlockHeader=a,t.cramBlockCrc32=s,t.cramTagDictionary=o,t.cramPreservationMap=c,t.isMappedSliceHeader=function(e){return "number"==typeof e.refSeqId},t.getSectionParsers=function(e){return {cramFileDefinition:i(),cramBlockHeader:a(),cramBlockCrc32:s(),cramDataSeriesEncodingMap:g(),cramTagEncodingMap:h(),cramCompressionHeader:{parser:(e,t)=>{const{value:r,offset:n}=c().parser(e,t);t=n;const{value:i,offset:a}=g().parser(e,t);t=a;const{value:s,offset:A}=h().parser(e,t);return t=A,{value:{dataSeriesEncoding:d(i),preservation:d(r),tagEncoding:d(s)},offset:t}}},cramEncoding:{parser:(e,t)=>u(e,t)},cramUnmappedSliceHeader:l(e),cramMappedSliceHeader:f(e),cramContainerHeader1:C(e),cramContainerHeader2:I(e)}};const n=r(2549);function i(){return {parser:(e,t=0)=>{const r=new DataView(e.buffer,e.byteOffset,e.length),n=new TextDecoder("utf8");let i=0;const a=n.decode(e.subarray(i,i+4));i+=4;const s=r.getUint8(i);i+=1;const A=r.getUint8(i);i+=1;const o=n.decode(e.subarray(i,i+20)).replaceAll("\0","");return i+=20,{value:{magic:a,majorVersion:s,minorVersion:A,fileId:o},offset:i}},maxLength:26}}function a(){return {parser:(e,t=0)=>{const r=e,i=new DataView(r.buffer,r.byteOffset,r.length);let a=0;const s=i.getUint8(a),A=["raw","gzip","bzip2","lzma","rans","rans4x16","arith","fqzcomp","tok3"][s];if(!A)throw new Error(`compression method number ${s} not implemented`);a+=1;const o=i.getUint8(a),c=["FILE_HEADER","COMPRESSION_HEADER","MAPPED_SLICE_HEADER","UNMAPPED_SLICE_HEADER","EXTERNAL_DATA","CORE_DATA"][o];if(!c)throw new Error(`invalid block content type id ${o}`);a+=1;const[d,l]=(0, n.parseItf8)(e,a);a+=l;const[f,u]=(0, n.parseItf8)(e,a);a+=u;const[g,h]=(0, n.parseItf8)(e,a);return a+=h,{offset:a,value:{uncompressedSize:g,compressedSize:f,contentId:d,contentType:c,compressionMethod:A}}},maxLength:17}}function s(){return {parser:(e,t)=>{const r=e,n=new DataView(r.buffer,r.byteOffset,r.length).getUint32(t,!0);return {offset:t+=4,value:{crc32:n}}},maxLength:4}}function A(e,t,r){const n=new TextDecoder("utf8").decode(e.subarray(t,r)),i=[];for(let e=0;e<n.length;e+=3)i.push(n.slice(e,e+3));return i}function o(){return {parser:(e,t)=>{const[r,i]=(0, n.parseItf8)(e,t);t+=i;const a=e.subarray(t,t+r);t+=r;const s=[];let o=0,c=0;for(;c<a.length;c++)a[c]||(s.push(A(a,o,c)),o=c+1);return c>o&&s.push(A(a,o,c)),{value:{size:r,ents:s},offset:t}}}}function c(){return {parser:(e,t)=>{const r=e,i=new DataView(r.buffer,r.byteOffset,r.length),[a,s]=(0, n.parseItf8)(e,t);t+=s;const[A,c]=(0, n.parseItf8)(e,t);t+=c;const d=[];for(let r=0;r<A;r++){const r=String.fromCharCode(e[t])+String.fromCharCode(e[t+1]);if(t+=2,"MI"===r||"UI"===r||"PI"===r||"RN"===r||"AP"===r||"RR"===r)d.push({key:r,value:!!i.getUint8(t)}),t+=1;else if("SM"===r)d.push({key:r,value:[i.getUint8(t),i.getUint8(t+1),i.getUint8(t+2),i.getUint8(t+3),i.getUint8(t+4)]}),t+=5;else {if("TD"!==r)throw new Error(`unknown key ${r}`);{const{offset:n,value:i}=o().parser(e,t);d.push({key:r,value:i.ents}),t=n;}}}return {value:{mapSize:a,mapCount:A,ents:d},offset:t}}}}function d(e){const t={};for(const{key:r,value:n}of e.ents)t[r]&&console.warn(`duplicate key ${r} in map`),t[r]=n;return t}function l(e){return {parser:(t,r)=>{const[i,a]=(0, n.parseItf8)(t,r);r+=a;let s=0;if(e>=3){const[e,i]=(0, n.parseLtf8)(t,r);r+=i,s=e;}else if(2===e){const[e,i]=(0, n.parseItf8)(t,r);r+=i,s=e;}else console.warn("recordCounter=0");const[A,o]=(0, n.parseItf8)(t,r);r+=o;const[c,d]=(0, n.parseItf8)(t,r);r+=d;const l=[];for(let e=0;e<c;e++){const[e,i]=(0, n.parseItf8)(t,r);r+=i,l.push(e);}let f;return e>=2&&(f=[...t.subarray(r,r+16)],r+=16),{value:{recordCounter:s,md5:f,contentIds:l,numContentIds:c,numBlocks:A,numRecords:i},offset:r}},maxLength:e=>40+5*e}}function f(e){return {parser:(t,r)=>{const[i,a]=(0, n.parseItf8)(t,r);r+=a;const[s,A]=(0, n.parseItf8)(t,r);r+=A;const[o,c]=(0, n.parseItf8)(t,r);r+=c;const[d,l]=(0, n.parseItf8)(t,r);r+=l;let f=0;if(e>=3){const[e,i]=(0, n.parseLtf8)(t,r);r+=i,f=e;}else if(2===e){const[e,i]=(0, n.parseItf8)(t,r);r+=i,f=e;}else console.warn("majorVersion is <2, recordCounter set to 0");const[u,g]=(0, n.parseItf8)(t,r);r+=g;const[h,C]=(0, n.parseItf8)(t,r);r+=C;const I=[];for(let e=0;e<h;e++){const[e,i]=(0, n.parseItf8)(t,r);r+=i,I.push(e);}const[_,m]=(0, n.parseItf8)(t,r);let B;return r+=m,e>=2&&(B=[...t.subarray(r,r+16)],r+=16),{value:{md5:B,numBlocks:u,numRecords:d,numContentIds:h,refSeqSpan:o,refSeqId:i,refSeqStart:s,recordCounter:f,refBaseBlockId:_,contentIds:I},offset:r}},maxLength:e=>60+5*e}}function u(e,t){const r=e,i=new DataView(r.buffer,r.byteOffset,r.length),[a,s]=(0, n.parseItf8)(e,t);t+=s;const[A,o]=(0, n.parseItf8)(e,t);t+=o;const c={};if(0===a);else if(1===a){const[r,i]=(0, n.parseItf8)(e,t);c.blockContentId=r,t+=i;}else if(2===a){const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;const[a,s]=(0, n.parseItf8)(e,t);c.M=a,t+=s;}else if(3===a){const r=(0, n.parseItf8)(e,t),i=r[0];t+=r[1];const a=[];for(let r=0;r<i;r++){const r=(0, n.parseItf8)(e,t);a.push(r[0]),t+=r[1];}c.symbols=a;const s=(0, n.parseItf8)(e,t),A=r[0];c.numLengths=A,c.numCodes=i,c.numLengths=A,t+=s[1];const o=[];for(let r=0;r<A;r++){const r=(0, n.parseItf8)(e,t);t+=r[1],o.push(r[0]);}c.bitLengths=o;}else if(4===a){const{value:r,offset:n}=u(e,t);c.lengthsEncoding=r,t=n;const{value:i,offset:a}=u(e,t);c.valuesEncoding=i,t=a;}else if(5===a){c.stopByte=i.getUint8(t),t+=1;const[r,a]=(0, n.parseItf8)(e,t);c.blockContentId=r,t+=a;}else if(6===a){const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;const[a,s]=(0, n.parseItf8)(e,t);c.length=a,t+=s;}else if(7===a){const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;const[a,s]=(0, n.parseItf8)(e,t);c.K=a,t+=s;}else if(8===a){const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;const[a,s]=(0, n.parseItf8)(e,t);c.log2m=a,t+=s;}else {if(9!==a)throw new Error(`unknown codecId ${a}`);{const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;}}return {value:{codecId:a,parametersBytes:A,parameters:c},offset:t}}function g(){return {parser:(e,t)=>{const[r,i]=(0, n.parseItf8)(e,t);t+=i;const[a,s]=(0, n.parseItf8)(e,t);t+=s;const A=[];for(let r=0;r<a;r++){const r=String.fromCharCode(e[t])+String.fromCharCode(e[t+1]);t+=2;const{value:n,offset:i}=u(e,t);t=i,A.push({key:r,value:n});}return {value:{mapSize:r,ents:A,mapCount:a},offset:t}}}}function h(){return {parser:(e,t)=>{const[r,i]=(0, n.parseItf8)(e,t);t+=i;const[a,s]=(0, n.parseItf8)(e,t);t+=s;const A=[];for(let r=0;r<a;r++){const[r,i]=(0, n.parseItf8)(e,t);t+=i;const a=String.fromCharCode(r>>16&255)+String.fromCharCode(r>>8&255)+String.fromCharCode(255&r),{value:s,offset:o}=u(e,t);t=o,A.push({key:a,value:s});}return {value:{mapSize:r,ents:A,mapCount:a},offset:t}}}}function C(e){return {maxLength:52,parser:(t,r)=>{const i=t,a=new DataView(i.buffer,i.byteOffset,i.length).getInt32(r,!0);r+=4;const[s,A]=(0, n.parseItf8)(t,r);r+=A;const[o,c]=(0, n.parseItf8)(t,r);r+=c;const[d,l]=(0, n.parseItf8)(t,r);r+=l;const[f,u]=(0, n.parseItf8)(t,r);r+=u;let g,h=0;if(e>=3){const[e,i]=(0, n.parseLtf8)(t,r);h=e,r+=i;}else if(2===e){const[e,i]=(0, n.parseItf8)(t,r);h=e,r+=i;}else console.warn("setting recordCounter=0");if(e>1){const[e,i]=(0, n.parseLtf8)(t,r);g=e,r+=i;}const[C,I]=(0, n.parseItf8)(t,r);r+=I;const[_,m]=(0, n.parseItf8)(t,r);return {value:{length:a,refSeqId:s,refSeqStart:o,alignmentSpan:d,numBlocks:C,numLandmarks:_,numBases:g,recordCounter:h,numRecords:f},offset:r+=m}}}}function I(e){return {parser:(t,r)=>{const i=t,a=new DataView(i.buffer,i.byteOffset,i.length),[s,A]=(0, n.parseItf8)(t,r);r+=A;const o=[];for(let e=0;e<s;e++){const[e,i]=(0, n.parseItf8)(t,r);r+=i,o.push(e);}let c;return e>=3&&(c=a.getUint32(r,!0),r+=4),{value:{...void 0===c?{}:{crc32:c},numLandmarks:s,landmarks:o},offset:r}},maxLength:e=>5+5*e+4}}},7593:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0});},7934:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(2549);class s extends i.default{constructor(e,t,r){super(e,t),this.instantiateCodec=r;}decode(e,t,r,n){const i=this._getLengthCodec().decode(e,t,r,n)||0,a=this._getDataCodec(),s=new Uint8Array(i);for(let A=0;A<i;A+=1)s[A]=a.decode(e,t,r,n)||0;return s}_getLengthCodec(){const e=this.parameters.lengthsEncoding;return this.instantiateCodec(e,"int")}_getDataCodec(){const e=this.parameters.valuesEncoding;return this.instantiateCodec(e,"byte")}}t.default=s,"_getLengthCodec _getDataCodec".split(" ").forEach((e=>{(0, a.tinyMemoize)(s,e);}));},8006:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(6272),s=r(6761);class A extends i.default{decode(e,t,r,n){const{blockContentId:i}=this.parameters,s=r[i];if(!s)throw new a.CramMalformedError(`no block found with content ID ${i}`);const A=n.externalBlocks.getCursor(i);return this._decodeByteArray(s,A)}_decodeByteArray(e,t){const r=e.content,{stopByte:n}=this.parameters,i=t.bytePosition;let a=t.bytePosition;for(;r[a]!==n&&a<r.length;){if(a===r.length)throw new s.CramBufferOverrunError("byteArrayStop reading beyond length of data buffer?");a+=1;}return t.bytePosition=a+1,r.subarray(i,a)}}t.default=A;},8223:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4997)),a=r(6272);t.default=class{constructor(e){if(this.cram=e.cram??new i.default({url:e.cramUrl,path:e.cramPath,filehandle:e.cramFilehandle,seqFetch:e.seqFetch,checkSequenceMD5:e.checkSequenceMD5,cacheSize:e.cacheSize}),!(this.cram instanceof i.default))throw new Error("invalid arguments: no cramfile");this.index=e.index;}async getRecordsForRange(e,t,r,n={}){if(n.viewAsPairs=n.viewAsPairs||!1,n.pairAcrossChr=n.pairAcrossChr||!1,n.maxInsertSize=n.maxInsertSize||2e5,"string"==typeof e)throw new a.CramUnimplementedError("string sequence names not yet supported");const i=e,s=await 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t,r,n,a,s,A=e.w_size;do{if(a=e.window_size-e.lookahead-e.strstart,e.strstart>=A+(A-l)){i.arraySet(e.window,e.window,A,A,0),e.match_start-=A,e.strstart-=A,e.block_start-=A,t=r=e.hash_size;do{n=e.head[--t],e.head[t]=n>=A?n-A:0;}while(--r);t=r=A;do{n=e.prev[--t],e.prev[t]=n>=A?n-A:0;}while(--r);a+=A;}if(0===e.strm.avail_in)break;if(r=w(e.strm,e.window,e.strstart+e.lookahead,a),e.lookahead+=r,e.lookahead+e.insert>=3)for(s=e.strstart-e.insert,e.ins_h=e.window[s],e.ins_h=(e.ins_h<<e.hash_shift^e.window[s+1])&e.hash_mask;e.insert&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[s+3-1])&e.hash_mask,e.prev[s&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=s,s++,e.insert--,!(e.lookahead+e.insert<3)););}while(e.lookahead<l&&0!==e.strm.avail_in)}function y(e,t){for(var r,n;;){if(e.lookahead<l){if(Q(e),e.lookahead<l&&0===t)return 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e.insert=e.strstart<2?e.strstart:2,4===t?(m(e,!0),0===e.strm.avail_out?3:4):e.last_lit&&(m(e,!1),0===e.strm.avail_out)?1:2}function b(e,t){for(var r,n,i;;){if(e.lookahead<l){if(Q(e),e.lookahead<l&&0===t)return 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if(e.match_available){if((n=a._tr_tally(e,0,e.window[e.strstart-1]))&&m(e,!1),e.strstart++,e.lookahead--,0===e.strm.avail_out)return 1}else e.match_available=1,e.strstart++,e.lookahead--;}return e.match_available&&(n=a._tr_tally(e,0,e.window[e.strstart-1]),e.match_available=0),e.insert=e.strstart<2?e.strstart:2,4===t?(m(e,!0),0===e.strm.avail_out?3:4):e.last_lit&&(m(e,!1),0===e.strm.avail_out)?1:2}function D(e,t,r,n,i){this.good_length=e,this.max_lazy=t,this.nice_length=r,this.max_chain=n,this.func=i;}function 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i.Buf16(573),I(this.depth),this.l_buf=0,this.lit_bufsize=0,this.last_lit=0,this.d_buf=0,this.opt_len=0,this.static_len=0,this.matches=0,this.insert=0,this.bi_buf=0,this.bi_valid=0;}function k(e){var t;return e&&e.state?(e.total_in=e.total_out=0,e.data_type=2,(t=e.state).pending=0,t.pending_out=0,t.wrap<0&&(t.wrap=-t.wrap),t.status=t.wrap?42:u,e.adler=2===t.wrap?0:1,t.last_flush=0,a._tr_init(t),0):h(e,c)}function v(e){var t,r=k(e);return 0===r&&((t=e.state).window_size=2*t.w_size,I(t.head),t.max_lazy_match=n[t.level].max_lazy,t.good_match=n[t.level].good_length,t.nice_match=n[t.level].nice_length,t.max_chain_length=n[t.level].max_chain,t.strstart=0,t.block_start=0,t.lookahead=0,t.insert=0,t.match_length=t.prev_length=2,t.match_available=0,t.ins_h=0),r}function R(e,t,r,n,a,s){if(!e)return c;var A=1;if(-1===t&&(t=6),n<0?(A=0,n=-n):n>15&&(A=2,n-=16),a<1||a>9||8!==r||n<8||n>15||t<0||t>9||s<0||s>4)return h(e,c);8===n&&(n=9);var o=new S;return 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e.insert=0,4===t?(m(e,!0),0===e.strm.avail_out?3:4):(e.strstart>e.block_start&&(m(e,!1),e.strm.avail_out),1)})),new D(4,4,8,4,y),new D(4,5,16,8,y),new D(4,6,32,32,y),new D(4,4,16,16,b),new D(8,16,32,32,b),new D(8,16,128,128,b),new D(8,32,128,256,b),new D(32,128,258,1024,b),new D(32,258,258,4096,b)],t.deflateInit=function(e,t){return R(e,t,8,15,8,0)},t.deflateInit2=R,t.deflateReset=v,t.deflateResetKeep=k,t.deflateSetHeader=function(e,t){return e&&e.state?2!==e.state.wrap?c:(e.state.gzhead=t,0):c},t.deflate=function(e,t){var r,i,s,o;if(!e||!e.state||t>5||t<0)return e?h(e,c):c;if(i=e.state,!e.output||!e.input&&0!==e.avail_in||i.status===g&&4!==t)return h(e,0===e.avail_out?-5:c);if(i.strm=e,r=i.last_flush,i.last_flush=t,42===i.status)if(2===i.wrap)e.adler=0,B(i,31),B(i,139),B(i,8),i.gzhead?(B(i,(i.gzhead.text?1:0)+(i.gzhead.hcrc?2:0)+(i.gzhead.extra?4:0)+(i.gzhead.name?8:0)+(i.gzhead.comment?16:0)),B(i,255&i.gzhead.time),B(i,i.gzhead.time>>8&255),B(i,i.gzhead.time>>16&255),B(i,i.gzhead.time>>24&255),B(i,9===i.level?2:i.strategy>=2||i.level<2?4:0),B(i,255&i.gzhead.os),i.gzhead.extra&&i.gzhead.extra.length&&(B(i,255&i.gzhead.extra.length),B(i,i.gzhead.extra.length>>8&255)),i.gzhead.hcrc&&(e.adler=A(e.adler,i.pending_buf,i.pending,0)),i.gzindex=0,i.status=69):(B(i,0),B(i,0),B(i,0),B(i,0),B(i,0),B(i,9===i.level?2:i.strategy>=2||i.level<2?4:0),B(i,3),i.status=u);else {var l=8+(i.w_bits-8<<4)<<8;l|=(i.strategy>=2||i.level<2?0:i.level<6?1:6===i.level?2:3)<<6,0!==i.strstart&&(l|=32),l+=31-l%31,i.status=u,p(i,l),0!==i.strstart&&(p(i,e.adler>>>16),p(i,65535&e.adler)),e.adler=1;}if(69===i.status)if(i.gzhead.extra){for(s=i.pending;i.gzindex<(65535&i.gzhead.extra.length)&&(i.pending!==i.pending_buf_size||(i.gzhead.hcrc&&i.pending>s&&(e.adler=A(e.adler,i.pending_buf,i.pending-s,s)),_(e),s=i.pending,i.pending!==i.pending_buf_size));)B(i,255&i.gzhead.extra[i.gzindex]),i.gzindex++;i.gzhead.hcrc&&i.pending>s&&(e.adler=A(e.adler,i.pending_buf,i.pending-s,s)),i.gzindex===i.gzhead.extra.length&&(i.gzindex=0,i.status=73);}else 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version ${r.majorVersion} not supported`);return r}async getSamHeader(){const e=await this.getContainerById(0);if(!e)throw new l.CramMalformedError("file contains no containers");const t=(await e.getFirstBlock()).content,r=new DataView(t.buffer).getInt32(0,!0),n=new TextDecoder("utf8").decode(t.subarray(4,4+r));return this.header=n,(0, h.parseHeaderText)(n)}async getHeaderText(){return await this.getSamHeader(),this.header}async getContainerById(e){const{majorVersion:t}=await this.getDefinition();let r,n=(0, m.getSectionParsers)(t).cramFileDefinition.maxLength;for(let t=0;t<=e;t++){r=this.getContainerAtPosition(n);const e=await r.getHeader();if(0===t){n=e._endPosition;for(let t=0;t<e.numBlocks;t++)n=(await this.readBlock(n))._endPosition;}else n+=e._size+e.length;}return r}async checkCrc32(e,t,r,n){const i=await this.file.read(t,e),a=(0, o.default)(i)>>>0;if(a!==r)throw new l.CramMalformedError(`crc mismatch in ${n}: recorded CRC32 = ${r}, but calculated CRC32 = ${a}`)}async containerCount(){const{majorVersion:e}=await this.getDefinition();let t=0,r=(0, m.getSectionParsers)(e).cramFileDefinition.maxLength;try{for(;;){const e=await this.getContainerAtPosition(r).getHeader();if(0===t){r=e._endPosition;for(let t=0;t<e.numBlocks;t++)r=(await this.readBlock(r))._endPosition;}else r+=e._size+e.length;t+=1;}}catch(e){t--;}return t}getContainerAtPosition(e){return new _.default(this,e)}async readBlockHeader(e){const{majorVersion:t}=await this.getDefinition(),r=(0, m.getSectionParsers)(t),{cramBlockHeader:n}=r,i=await this.file.read(n.maxLength,e);return (0, B.parseItem)(i,n.parser,0,e)}async _parseSection(e,t,r=e.maxLength,n){const i=n??await this.file.read(r,t),a=(0, B.parseItem)(i,e.parser,0,t);if(a._size!==r)throw new l.CramMalformedError(`section read error: requested size ${r} does not equal parsed size ${a._size}`);return a}async _uncompressPre(e,t,r){if("gzip"===e)return (0, I.unzip)(t);if("bzip2"===e)return (0, C.decode)(t);if("lzma"===e){const e=new Response(new d.XzReadableStream((n=t,new ReadableStream({start(e){e.enqueue(n),e.close();}}))));return new Uint8Array(await e.arrayBuffer())}if("rans"===e){const e=new Uint8Array(r);return (0, g.default)(t,e),e}if("rans4x16"===e)return f.r4x16_uncompress(t);if("arith"===e)return f.arith_uncompress(t);if("fqzcomp"===e)return f.fqzcomp_uncompress(t);if("tok3"===e)return f.tok3_uncompress(t);throw new l.CramUnimplementedError(`${e} decompression not yet implemented`);var n;}async _uncompress(e,t,r){const n=await this._uncompressPre(e,t,r);if(n.length!==r){const e=new Uint8Array(r);return e.set(n,0),e}return n}async readBlock(e){const{majorVersion:t}=await this.getDefinition(),r=(0, m.getSectionParsers)(t),n=await this.readBlockHeader(e),i=n._endPosition,a=await this.file.read(n.compressedSize,i),s="raw"!==n.compressionMethod?await this._uncompress(n.compressionMethod,a,n.uncompressedSize):a,A={...n,_endPosition:i,contentPosition:i,content:s};if(t>=3){const t=await this._parseSection(r.cramBlockCrc32,i+n.compressedSize);A.crc32=t.crc32,this.validateChecksums&&await this.checkCrc32(e,n._size+n.compressedSize,t.crc32,"block data"),A._endPosition=t._endPosition,A._size=A.compressedSize+r.cramBlockCrc32.maxLength;}else A._endPosition=i+A.compressedSize,A._size=A.compressedSize;return A}}t.default=p,"getDefinition getSectionParsers getSamHeader".split(" ").forEach((e=>{(0, B.tinyMemoize)(p,e);}));},8761:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0});const r=new Uint32Array([0,79764919,159529838,222504665,319059676,398814059,445009330,507990021,638119352,583659535,797628118,726387553,890018660,835552979,1015980042,944750013,1276238704,1221641927,1167319070,1095957929,1595256236,1540665371,1452775106,1381403509,1780037320,1859660671,1671105958,1733955601,2031960084,2111593891,1889500026,1952343757,2552477408,2632100695,2443283854,2506133561,2334638140,2414271883,2191915858,2254759653,3190512472,3135915759,3081330742,3009969537,2905550212,2850959411,2762807018,2691435357,3560074640,3505614887,3719321342,3648080713,3342211916,3287746299,3467911202,3396681109,4063920168,4143685023,4223187782,4286162673,3779000052,3858754371,3904687514,3967668269,881225847,809987520,1023691545,969234094,662832811,591600412,771767749,717299826,311336399,374308984,453813921,533576470,25881363,88864420,134795389,214552010,2023205639,2086057648,1897238633,1976864222,1804852699,1867694188,1645340341,1724971778,1587496639,1516133128,1461550545,1406951526,1302016099,1230646740,1142491917,1087903418,2896545431,2825181984,2770861561,2716262478,3215044683,3143675388,3055782693,3001194130,2326604591,2389456536,2200899649,2280525302,2578013683,2640855108,2418763421,2498394922,3769900519,3832873040,3912640137,3992402750,4088425275,4151408268,4197601365,4277358050,3334271071,3263032808,3476998961,3422541446,3585640067,3514407732,3694837229,3640369242,1762451694,1842216281,1619975040,1682949687,2047383090,2127137669,1938468188,2001449195,1325665622,1271206113,1183200824,1111960463,1543535498,1489069629,1434599652,1363369299,622672798,568075817,748617968,677256519,907627842,853037301,1067152940,995781531,51762726,131386257,177728840,240578815,269590778,349224269,429104020,491947555,4046411278,4126034873,4172115296,4234965207,3794477266,3874110821,3953728444,4016571915,3609705398,3555108353,3735388376,3664026991,3290680682,3236090077,3449943556,3378572211,3174993278,3120533705,3032266256,2961025959,2923101090,2868635157,2813903052,2742672763,2604032198,2683796849,2461293480,2524268063,2284983834,2364738477,2175806836,2238787779,1569362073,1498123566,1409854455,1355396672,1317987909,1246755826,1192025387,1137557660,2072149281,2135122070,1912620623,1992383480,1753615357,1816598090,1627664531,1707420964,295390185,358241886,404320391,483945776,43990325,106832002,186451547,266083308,932423249,861060070,1041341759,986742920,613929101,542559546,756411363,701822548,3316196985,3244833742,3425377559,3370778784,3601682597,3530312978,3744426955,3689838204,3819031489,3881883254,3928223919,4007849240,4037393693,4100235434,4180117107,4259748804,2310601993,2373574846,2151335527,2231098320,2596047829,2659030626,2470359227,2550115596,2947551409,2876312838,2788305887,2733848168,3165939309,3094707162,3040238851,2985771188]);t.default=class{constructor(){this.crc=4294967295;}getCRC(){return ~this.crc>>>0}updateCRC(e){this.crc=this.crc<<8^r[255&(this.crc>>>24^e)];}updateCRCRun(e,t){for(;t-- >0;)this.crc=this.crc<<8^r[255&(this.crc>>>24^e)];}};},8930:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(6272),s=r(2549),A=r(6761);class o extends i.default{constructor(e,t){if(super(e,t),"int"===this.dataType)this._decodeData=this._decodeInt;else {if("byte"!==this.dataType)throw new a.CramUnimplementedError(`${this.dataType} decoding not yet implemented by EXTERNAL codec`);this._decodeData=this._decodeByte;}}decode(e,t,r,n){const{blockContentId:i}=this.parameters,a=r[i];return a?this._decodeData(a,n.externalBlocks.getCursor(i)):void 0}_decodeInt(e,t){const[r,n]=(0, s.parseItf8)(e.content,t.bytePosition);return t.bytePosition=t.bytePosition+n,r}_decodeByte(e,t){if(t.bytePosition>=e.content.length)throw new A.CramBufferOverrunError("attempted to read beyond end of block. this file seems truncated.");return e.content[t.bytePosition++]}}t.default=o;},9301:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0});const n=r(6272),i=r(7151);class a{constructor(){this.F=void 0,this.C=void 0;}}function s(e,t,r,n){return r*(e>>n)+(e&(1<<n)-1)-t}t.default={FC:a,AriDecoder:class{constructor(){this.fc=new Array(256);for(let e=0;e<this.fc.length;e+=1)this.fc[e]=new a;this.R=null;}},DecodingSymbol:class{constructor(){this.start=void 0,this.freq=void 0;}},symbolInit:function(e,t,r){if(!(t<=65536))throw new n.CramMalformedError("assertion failed: start <= 1<<16");if(!(r<=65536-t))throw new n.CramMalformedError("assertion failed: freq <= 1<<16");e.start=t,e.freq=r;},advanceStep:s,advanceSymbolStep:function(e,t,r){return s(e,t.start,t.freq,r)},get:function(e,t){return e&(1<<t)-1},advanceSymbol:function(e,t,r,n){return function(e,t,r,n,a){if((e=n*(e>>a)+(e&(1<<a)-1)-r)<i.RANS_BYTE_L)do{e=e<<8|255&t.get();}while(e<i.RANS_BYTE_L);return e}(e,t,r.start,r.freq,n)},renormalize:function(e,t){if(e<i.RANS_BYTE_L)do{e=e<<8|255&t.get();}while(e<i.RANS_BYTE_L);return e}};},9313:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.decode=function(e){return d(new i.default(e),0)};const i=n(r(3088));function a(e,t){return e&(1<<t)-1}function s(e,t){let r=0;for(;t>=e[r+1];)r++;return r}function A(e,t){const r=1<<t,n=new Array(r);let i=0;for(let t=0;t<r;t++){for(;t>=e[i+1];)i++;n[t]=i;}return n}function o(e,t,r,n){return r*(e>>n)+(e&(1<<n)-1)-t}function c(e,t){return t<32768&&(t=(t<<16)+e.ReadUint16()),t}function d(e,t){const r=e.ReadByte(),n=1&r,g=8&r,h=32&r,C=64&r,I=128&r,_=4&r?32:4;if(16&r||(t=e.ReadUint7()),g)return function(e,t){const r=e.ReadByte(),n=new Array(r),i=new Array(r);for(var a=0;a<r;a++)n[a]=e.ReadUint7();const s=new Array(r);for(a=0;a<r;a++)i[a]=Math.floor(t/r)+(t%r>a),s[a]=d(e,i[a]);const A=new Uint8Array(t);for(a=0;a<r;a++)for(let e=0;e<i[a];e++)A[e*r+a]=s[a][e];return A}(e,t);if(I)var m=t,[B,p,t]=function(e){const t=e.ReadByte(),r=new Array(t);for(let n=0;n<t;n++)r[n]=e.ReadByte();return [r,t,e.ReadUint7()]}(e);if(C)var w=t,[E,Q,t]=function(e,t){const r=e.ReadUint7(),n=e.ReadUint7();if(1&r)var a=e.ReadData((r-1)/2);else {const n=e.ReadUint7();a=e.ReadData(n),a=f(new i.default(a),r/2,t);}a=new i.default(a);const s=new Array(256);let A=a.ReadByte();0==A&&(A=256);for(let e=0;e<A;e++)s[a.ReadByte()]=1;return [s,a,n]}(e,_);if(h)var y=e.ReadData(t);else y=0==n?f(e,t,_):function(e,t,r){const n=(g=e.ReadByte())>>4;var d=e;if(1&g){const t=e.ReadUint7(),r=e.ReadUint7();var g=new i.default(e.ReadData(r));d=new i.default(f(g,t,4));}const h=new Array(256),C=new Array(256);!function(e,t,r,n){for(var i=0;i<256;i++){t[i]=new Array(256),r[i]=new Array(256);for(var a=0;a<256;a++)t[i][a]=0;}const s=l(e);for(i=0;i<256;i++){if(!s[i])continue;let A=0;for(a=0;a<256;a++)s[a]&&(A>0?A--:(t[i][a]=e.ReadUint7(),0==t[i][a]&&(A=e.ReadByte())));for(u(t[i],n),r[i][0]=0,a=0;a<256;a++)r[i][a+1]=r[i][a]+t[i][a];}}(d,h,C,n);const I=new Array(256);for(var _=0;_<256;_++)I[_]=A(C[_],n);const m=new Array(r),B=new Array(r);for(var p=0;p<r;p++)m[p]=e.ReadUint32(),B[p]=0;const w=new Uint8Array(t),E=Math.floor(t/r);for(_=0;_<E;_++)for(p=0;p<r;p++){var Q=a(m[p],n),y=I[B[p]][Q];w[_+p*E]=y,m[p]=o(m[p],C[B[p]][y],h[B[p]][y],n),m[p]=c(e,m[p]),B[p]=y;}for(_*=r;_<t;)Q=a(m[r-1],n),y=s(C[B[r-1]],Q),w[_++]=y,m[r-1]=o(m[r-1],C[B[r-1]][y],h[B[r-1]][y],n),m[r-1]=c(e,m[r-1]),B[r-1]=y;return w}(e,t,_);return C&&(y=function(e,t,r,n){new i.default(e);const a=new Uint8Array(n);let s=0;for(let i=0;s<n;i++){const n=e[i];if(t[n]){const e=r.ReadUint7();for(let t=0;t<=e;t++)a[s++]=n;}else a[s++]=n;}return a}(y,E,Q,w)),I&&(y=function(e,t,r,n){const i=new Uint8Array(n);let a=0;if(r<=1)for(var s=0;s<n;s++)i[s]=t[0];else if(r<=2)for(s=0;s<n;s++){if(s%8==0)var A=e[a++];i[s]=t[1&A],A>>=1;}else if(r<=4)for(s=0;s<n;s++)s%4==0&&(A=e[a++]),i[s]=t[3&A],A>>=2;else if(r<=16)for(s=0;s<n;s++)s%2==0&&(A=e[a++]),i[s]=t[15&A],A>>=4;return i}(y,B,p,m)),y}function l(e){const t=new Array(256);for(let e=0;e<256;e++)t[e]=0;let r=0,n=e.ReadByte(),i=n;do{t[n]=1,r>0?(r--,n++):(n=e.ReadByte(),n==i+1&&(r=e.ReadByte())),i=n;}while(0!=n);return t}function f(e,t,r){const n=new Array(256),i=new Array(256);!function(e,t,r){for(var n=0;n<256;n++)t[n]=0;const i=l(e);for(n=0;n<256;n++)i[n]>0&&(t[n]=e.ReadUint7());for(u(t,12),r[0]=0,n=0;n<=255;n++)r[n+1]=r[n]+t[n];}(e,n,i);const s=A(i,12),d=new Array(r);for(var f=0;f<r;f++)d[f]=e.ReadUint32();const g=new Uint8Array(t);for(f=0;f<t;f++){const t=f&r-1,A=s[a(d[t],12)];g[f]=A,d[t]=o(d[t],i[A],n[A],12),d[t]=c(e,d[t]);}return g}function u(e,t){let r=0;for(var n=0;n<256;n++)r+=e[n];if(0==r||r==1<<t)return;let i=0;for(;r<1<<t;)r*=2,i++;for(n=0;n<256;n++)e[n]<<=i;}},9505:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=r(870),a=n(r(4652)),s=n(r(2324)),A=n(r(3088));t.default=class{decode(e){return this.stream=new A.default(e),this.decodeStream(this.stream)}decodeStream(e,t=0){const r=this.stream.ReadByte();16&r||(t=this.stream.ReadUint7());let n=t;const i=1&r;if(8&r)return this.decodeStripe(this.stream,t);var a;if(128&r&&([a,n]=this.decodePackMeta(this.stream)),32&r)var s=this.decodeCat(this.stream,n);else s=4&r?this.decodeExt(this.stream,n):64&r?i?this.decodeRLE1(this.stream,n):this.decodeRLE0(this.stream,n):i?this.decode1(this.stream,n):this.decode0(this.stream,n);return 128&r&&(s=this.decodePack(s,a,t)),s}decode0(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new s.default(n),A=new a.default(e);A.RangeStartDecode(e);for(let n=0;n<t;n++)r[n]=i.ModelDecode(e,A);return r}decode1(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new Array(n);for(var A=0;A<n;A++)i[A]=new s.default(n);const o=new a.default(e);o.RangeStartDecode(e);let c=0;for(A=0;A<t;A++)r[A]=i[c].ModelDecode(e,o),c=r[A];return r}decodeExt(e,t){return (0, i.decode)(e.buf.slice(e.pos))}decodeRLE0(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new s.default(n),A=new Array(258);for(var o=0;o<=257;o++)A[o]=new s.default(4);const c=new a.default(e);for(c.RangeStartDecode(e),o=0;o<t;){r[o]=i.ModelDecode(e,c);let t=A[r[o]].ModelDecode(e,c),n=t,a=256;for(;3==t;)t=A[a].ModelDecode(e,c),a=257,n+=t;for(let e=1;e<=n;e++)r[o+e]=r[o];o+=n+1;}return r}decodeRLE1(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new Array(n);for(var A=0;A<n;A++)i[A]=new s.default(n);const o=new Array(258);for(A=0;A<=257;A++)o[A]=new s.default(4);const c=new a.default(e);c.RangeStartDecode(e);let d=0;for(A=0;A<t;){r[A]=i[d].ModelDecode(e,c),d=r[A];let t=o[r[A]].ModelDecode(e,c),n=t,a=256;for(;3==t;)t=o[a].ModelDecode(e,c),a=257,n+=t;for(let e=1;e<=n;e++)r[A+e]=r[A];A+=n+1;}return r}decodePackMeta(e){this.nsym=e.ReadByte();const t=new Array(this.nsym);for(let r=0;r<this.nsym;r++)t[r]=e.ReadByte();return [t,e.ReadUint7()]}decodePack(e,t,r){const n=new Uint8Array(r);if(this.nsym<=1)for(var i=0;i<r;i++)n[i]=t[0];else if(this.nsym<=2){i=0;for(var a=0;i<r;i++){if(i%8==0)var s=e[a++];n[i]=t[1&s],s>>=1;}}else if(this.nsym<=4)for(i=0,a=0;i<r;i++)i%4==0&&(s=e[a++]),n[i]=t[3&s],s>>=2;else {if(!(this.nsym<=16))return e;for(i=0,a=0;i<r;i++)i%2==0&&(s=e[a++]),n[i]=t[15&s],s>>=4;}return n}packMeta(e){const t=new A.default("",0,1024),r=new Array(256);for(var n=0;n<e.length;n++)r[e[n]]=1;var i=0;for(n=0;n<256;n++)r[n]&&(r[n]=++i);for(t.WriteByte(i),n=0;n<256;n++)r[n]&&(t.WriteByte(n),r[n]--);return [t,r,i]}decodeStripe(e,t){const r=e.ReadByte(),n=new Array(r),i=new Array(r);for(var a=0;a<r;a++)n[a]=e.ReadUint7();const s=new Array(r);for(a=0;a<r;a++)i[a]=Math.floor(t/r)+(t%r>a),s[a]=this.decodeStream(e,i[a]);const A=new Uint8Array(t);for(a=0;a<r;a++)for(let e=0;e<i[a];e++)A[e*r+a]=s[a][e];return A}decodeCat(e,t){const r=new Uint8Array(t);for(let n=0;n<t;n++)r[n]=e.ReadByte();return r}};},9681:e=>{e.exports={Z_NO_FLUSH:0,Z_PARTIAL_FLUSH:1,Z_SYNC_FLUSH:2,Z_FULL_FLUSH:3,Z_FINISH:4,Z_BLOCK:5,Z_TREES:6,Z_OK:0,Z_STREAM_END:1,Z_NEED_DICT:2,Z_ERRNO:-1,Z_STREAM_ERROR:-2,Z_DATA_ERROR:-3,Z_BUF_ERROR:-5,Z_NO_COMPRESSION:0,Z_BEST_SPEED:1,Z_BEST_COMPRESSION:9,Z_DEFAULT_COMPRESSION:-1,Z_FILTERED:1,Z_HUFFMAN_ONLY:2,Z_RLE:3,Z_FIXED:4,Z_DEFAULT_STRATEGY:0,Z_BINARY:0,Z_TEXT:1,Z_UNKNOWN:2,Z_DEFLATED:8};},9685:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=function(e,t,r,o,c,d,l,f,u){let g=t("BF");const h=t("CF");if(!(0, a.isMappedSliceHeader)(o.parsedContent))throw new Error("slice header not mapped");const C=f>1&&-2===o.parsedContent.refSeqId?t("RI"):o.parsedContent.refSeqId,I=t("RL");let _=t("AP");r.APdelta&&(_+=l.lastAlignmentStart),l.lastAlignmentStart=_;const m=t("RG");let B,p,w,E;if(r.readNamesIncluded&&(B=s(t("RN"))),i.CramFlagsDecoder.isDetached(h)){const e=t("MF");let n;r.readNamesIncluded||(n=s(t("RN")),B=n);const a=t("NS"),A=t("NP");(e||a>-1)&&(p={mateFlags:e,mateSequenceId:a,mateAlignmentStart:A,mateReadName:n}),w=t("TS"),i.MateFlagsDecoder.isUnmapped(e)&&(g=i.BamFlagsDecoder.setMateUnmapped(g)),i.MateFlagsDecoder.isOnNegativeStrand(e)&&(g=i.BamFlagsDecoder.setMateReverseComplemented(g));}else i.CramFlagsDecoder.isWithMateDownstream(h)&&(E=t("NF")+u+1);const Q=t("TL");if(Q<0)throw new n.CramMalformedError("invalid TL index");const y={},b=r.getTagNames(Q),D=b.length;for(let t=0;t<D;t++){const n=b[t],i=n.slice(0,2),a=n.slice(2,3),s=r.getCodecForTag(n).decode(e,c,d,l);y[i]=void 0===s?void 0:"number"==typeof s?s:A(a,s);}let S,k,v,R,F;if(i.BamFlagsDecoder.isSegmentUnmapped(g))if(i.CramFlagsDecoder.isDecodeSequenceAsStar(h))F=null,R=null;else {const e=new Array(I);for(let r=0;r<e.length;r++)e[r]=t("BA");if(F=String.fromCharCode(...e),i.CramFlagsDecoder.isPreservingQualityScores(h)){R=new Array(I);for(let r=0;r<e.length;r++)R[r]=t("QS");}}else {const e=t("FN");if(e&&(S=function(e,t,r,i,a){let s=0,A=e-1;const o=new Array(t);function c([e,t]){const n=r(t);if("character"===e)return String.fromCharCode(n);if("string"===e){let e="";for(let t=0;t<n.byteLength;t++)e+=String.fromCharCode(n[t]);return e}return "numArray"===e?Array.from(n):n}for(let e=0;e<t;e++){const t=String.fromCharCode(r("FC")),i=r("FP"),d={B:["character","BA"],S:["string",a>1?"SC":"IN"],X:["number","BS"],D:["number","DL"],I:["string","IN"],i:["character","BA"],b:["string","BB"],q:["numArray","QQ"],Q:["number","QS"],H:["number","HC"],P:["number","PD"],N:["number","RS"]}[t];if(!d)throw new n.CramMalformedError(`invalid read feature code "${t}"`);let l=c(d);const f={B:["number","QS"]}[t];f&&(l=[l,c(f)]),s+=i;const u=s;A+=i;const 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A=0;A<b;A++){const[A,e]=Q(t,r);r+=e,o.push(A);}let a;return A>=2&&(a=[...t.subarray(r,r+16)],r+=16),{value:{recordCounter:n,md5:a,contentIds:o,numContentIds:b,numBlocks:f,numRecords:e},offset:r}},maxLength:A=>40+5*A}}function yA(A){return {parser:(t,r)=>{const[e,v]=Q(t,r);r+=v;const[n,j]=Q(t,r);r+=j;const[f,s]=Q(t,r);r+=s;const[b,i]=Q(t,r);r+=i;const[o,a]=uA(t,r,A);r+=a;const[g,I]=Q(t,r);r+=I;const[c,C]=Q(t,r);r+=C;const E=[];for(let A=0;A<c;A++){const[A,e]=Q(t,r);r+=e,E.push(A);}const[l,h]=Q(t,r);let d;return r+=h,A>=2&&(d=[...t.subarray(r,r+16)],r+=16),{value:{md5:d,numBlocks:g,numRecords:b,numContentIds:c,refSeqSpan:f,refSeqId:e,refSeqStart:n,recordCounter:o,refBaseBlockId:l,contentIds:E},offset:r}},maxLength:A=>60+5*A}}function DA(A,t){const r=A,e=new DataView(r.buffer,r.byteOffset,r.length),[v,n]=Q(A,t);t+=n;const[j,f]=Q(A,t);t+=f;const s={};if(0===v);else if(1===v){const[r,e]=Q(A,t);s.blockContentId=r,t+=e;}else if(2===v){const[r,e]=Q(A,t);s.offset=r,t+=e;const[v,n]=Q(A,t);s.M=v,t+=n;}else if(3===v){const[r,e]=Q(A,t);t+=e;const v=[];for(let e=0;e<r;e++){const[r,e]=Q(A,t);v.push(r),t+=e;}const[n,j]=Q(A,t);t+=j;const f=[];for(let r=0;r<n;r++){const[r,e]=Q(A,t);t+=e,f.push(r);}s.numCodes=r,s.symbols=v,s.numLengths=n,s.bitLengths=f;}else if(4===v){const{value:r,offset:e}=DA(A,t);s.lengthsEncoding=r,t=e;const{value:v,offset:n}=DA(A,t);s.valuesEncoding=v,t=n;}else if(5===v){s.stopByte=e.getUint8(t),t+=1;const[r,v]=Q(A,t);s.blockContentId=r,t+=v;}else if(6===v){const[r,e]=Q(A,t);s.offset=r,t+=e;const[v,n]=Q(A,t);s.length=v,t+=n;}else if(7===v){const[r,e]=Q(A,t);s.offset=r,t+=e;const[v,n]=Q(A,t);s.K=v,t+=n;}else if(8===v){const[r,e]=Q(A,t);s.offset=r,t+=e;const[v,n]=Q(A,t);s.log2m=v,t+=n;}else {if(9!==v)throw new Error(`unknown codecId ${v}`);{const[r,e]=Q(A,t);s.offset=r,t+=e;}}return {value:{codecId:v,parametersBytes:j,parameters:s},offset:t}}function FA(){return {parser:(A,t)=>{const[r,e]=Q(A,t);t+=e;const[v,n]=Q(A,t);t+=n;const j=[];for(let r=0;r<v;r++){const r=String.fromCharCode(A[t])+String.fromCharCode(A[t+1]);t+=2;const{value:e,offset:v}=DA(A,t);t=v,j.push({key:r,value:e});}return {value:{mapSize:r,ents:j,mapCount:v},offset:t}}}}function SA(){return {parser:(A,t)=>{const[r,e]=Q(A,t);t+=e;const[v,n]=Q(A,t);t+=n;const j=[];for(let r=0;r<v;r++){const[r,e]=Q(A,t);t+=e;const v=String.fromCharCode(r>>16&255)+String.fromCharCode(r>>8&255)+String.fromCharCode(255&r),{value:n,offset:f}=DA(A,t);t=f,j.push({key:v,value:n});}return {value:{mapSize:r,ents:j,mapCount:v},offset:t}}}}function GA(A){return {maxLength:52,parser:(t,r)=>{const e=t,v=new DataView(e.buffer,e.byteOffset,e.length).getInt32(r,!0);r+=4;const[n,j]=Q(t,r);r+=j;const[f,s]=Q(t,r);r+=s;const[b,i]=Q(t,r);r+=i;const[o,a]=Q(t,r);r+=a;const[g,I]=uA(t,r,A);let c;if(r+=I,A>1){const[A,e]=x(t,r);c=A,r+=e;}const[C,E]=Q(t,r);r+=E;const[l,h]=Q(t,r);return {value:{length:v,refSeqId:n,refSeqStart:f,alignmentSpan:b,numBlocks:C,numLandmarks:l,numBases:c,recordCounter:g,numRecords:o},offset:r+=h}}}}function RA(A){return {parser:(t,r)=>{const e=t,v=new DataView(e.buffer,e.byteOffset,e.length),[n,j]=Q(t,r);r+=j;const f=[];for(let A=0;A<n;A++){const[A,e]=Q(t,r);r+=e,f.push(A);}let s;return A>=3&&(s=v.getUint32(r,!0),r+=4),{value:{...void 0===s?{}:{crc32:s},numLandmarks:n,landmarks:f},offset:r}},maxLength:A=>5+5*A+4}}function KA(A){return {cramFileDefinition:QA(),cramBlockHeader:{parser:(A,t=0)=>{const r=A,e=new DataView(r.buffer,r.byteOffset,r.length);let v=0;const n=e.getUint8(v),j=BA[n];if(!j)throw new Error(`compression method number ${n} not implemented`);v+=1;const f=e.getUint8(v),s=qA[f];if(!s)throw new Error(`invalid block content type id ${f}`);v+=1;const[b,i]=Q(A,v);v+=i;const[o,a]=Q(A,v);v+=a;const[g,I]=Q(A,v);return v+=I,{offset:v,value:{uncompressedSize:g,compressedSize:o,contentId:b,contentType:s,compressionMethod:j}}},maxLength:17},cramBlockCrc32:{parser:(A,t)=>{const r=A,e=new DataView(r.buffer,r.byteOffset,r.length).getUint32(t,!0);return {offset:t+=4,value:{crc32:e}}},maxLength:4},cramDataSeriesEncodingMap:FA(),cramTagEncodingMap:SA(),cramCompressionHeader:{parser:(A,t)=>{const{value:r,offset:e}=((A,t)=>{const r=A,e=new DataView(r.buffer,r.byteOffset,r.length),[v,n]=Q(A,t);t+=n;const[j,f]=Q(A,t);t+=f;const s=[];for(let r=0;r<j;r++){const r=String.fromCharCode(A[t])+String.fromCharCode(A[t+1]);if(t+=2,"MI"===r||"UI"===r||"PI"===r||"RN"===r||"AP"===r||"RR"===r)s.push({key:r,value:!!e.getUint8(t)}),t+=1;else if("SM"===r)s.push({key:r,value:[e.getUint8(t),e.getUint8(t+1),e.getUint8(t+2),e.getUint8(t+3),e.getUint8(t+4)]}),t+=5;else {if("TD"!==r)throw new Error(`unknown key ${r}`);{const{offset:e,value:v}=mA().parser(A,t);s.push({key:r,value:v.ents}),t=e;}}}return {value:{mapSize:v,mapCount:j,ents:s},offset:t}})(A,t);t=e;const{value:v,offset:n}=FA().parser(A,t);t=n;const{value:j,offset:f}=SA().parser(A,t);return t=f,{value:{dataSeriesEncoding:NA(v),preservation:NA(r),tagEncoding:NA(j)},offset:t}}},cramEncoding:{parser:(A,t)=>DA(A,t)},cramUnmappedSliceHeader:pA(A),cramMappedSliceHeader:yA(A),cramContainerHeader1:GA(A),cramContainerHeader2:RA(A)}}function MA(A,t){if("Z"===A)return k(t);if("A"===A)return String.fromCharCode(t[0]);if("C"===A)return t[0];if("c"===A)return t[0]>127?t[0]-256:t[0];if("B"===A)return function(A){const t=String.fromCharCode(A[0]),r=new DataView(A.buffer,A.byteOffset,A.byteLength),e=r.getUint32(1,!0),v=new Array(e);if("c"===t)for(let A=0;A<e;A++)v[A]=r.getInt8(5+A);else if("C"===t)for(let A=0;A<e;A++)v[A]=r.getUint8(5+A);else if("s"===t)for(let A=0;A<e;A++)v[A]=r.getInt16(5+2*A,!0);else if("S"===t)for(let A=0;A<e;A++)v[A]=r.getUint16(5+2*A,!0);else if("i"===t)for(let A=0;A<e;A++)v[A]=r.getInt32(5+4*A,!0);else if("I"===t)for(let A=0;A<e;A++)v[A]=r.getUint32(5+4*A,!0);else {if("f"!==t)throw new Error(`unknown type: ${t}`);for(let A=0;A<e;A++)v[A]=r.getFloat32(5+4*A,!0);}return v}(t);if("H"===A)return Number.parseInt(k(t).replace(/^0x/,""),16);const r=new DataView(t.buffer,t.byteOffset,t.byteLength);if("I"===A)return r.getUint32(0,!0);if("i"===A)return r.getInt32(0,!0);if("s"===A)return r.getInt16(0,!0);if("S"===A)return r.getUint16(0,!0);if("f"===A)return r.getFloat32(0,!0);throw new nA(`Unrecognized tag type ${A}`)}function OA(A,t,r){const e=t?.("QS",A);if(e)return e;const v=new Uint8Array(A);for(let t=0;t<A;t++)v[t]=r();return v}function HA(A,t,r,e,v,n,j,f,s,b,i,o,a,g){let I=t.BF();const c=t.CF();if(!wA(n.parsedContent))throw new Error("slice header not mapped");const C=b>1&&-2===n.parsedContent.refSeqId?t.RI():n.parsedContent.refSeqId,E=t.RL();let l=t.AP();v.APdelta&&(l+=s.lastAlignmentStart),s.lastAlignmentStart=l;const h=t.RG();let d,q,u,Q;if(v.readNamesIncluded&&(d=t.RN()),S.isDetached(c)){const A=t.MF();let r;v.readNamesIncluded||(d=t.RN(),r=k(d));const e=t.NS(),n=t.NP();(A||e>-1)&&(q={flags:A,sequenceId:e,alignmentStart:n,readName:r}),u=t.TS(),G.isUnmapped(A)&&(I=F.setMateUnmapped(I)),G.isOnNegativeStrand(A)&&(I=F.setMateReverseComplemented(I));}else S.isWithMateDownstream(c)&&(Q=t.NF()+i+1);const x=t.TL();if(x<0)throw new nA("invalid TL index");const m={},N=v.getTagNames(x),w=N.length;if(!1!==a?.decodeTags)for(let A=0;A<w;A++){const t=N[A],r=e[t](),v=t[0]+t[1],n=t[2];m[v]=void 0===r?void 0:"number"==typeof r?r:MA(n,r);}let p,y,D,R,K;if(F.isSegmentUnmapped(I))S.isDecodeSequenceAsStar(c)?(K=null,R=null):(K=function(A,t,r){const e=t?.("BA",A);if(e)return B(e);const v=new Uint8Array(A);for(let t=0;t<A;t++)v[t]=r();return B(v)}(E,g,t.BA),S.isPreservingQualityScores(c)&&(R=OA(E,g,t.QS)));else {const A=t.FN();if(y=E,A){const[e,v]=function(A,t,r,e){let v=0,n=0;const j=A-1,f=new Array(t),s=r.FC,b=r.FP;for(let A=0;A<t;A++){const t=s();v+=b();const r=e[t];if(!r)throw new nA(`invalid read feature code "${String.fromCharCode(t)}"`);const i=r[0],o=r[1]();f[A]={code:i,pos:v,refPos:v+j+n,data:o},"D"===i||"N"===i?n+=o:"I"===i||"S"===i?n-=o.length:"i"===i&&(n-=1);}return [f,n]}(l,A,t,r);p=e,y+=v;}Number.isNaN(y)&&(console.warn(`${C}:${l} record has invalid read features`),y=E),D=t.MQ(),S.isPreservingQualityScores(c)&&(R=OA(E,g,t.QS));}return {readLength:E,sequenceId:C,cramFlags:c,flags:I,alignmentStart:l,readGroupId:h,readNameRaw:d,mate:q,templateSize:u,mateRecordNumber:Q,readFeatures:p,lengthOnRef:y,mappingQuality:D,qualityScores:R,readBases:K,tags:m,uniqueId:o}}function LA(A,t,r){let{bytePosition:e,bitPosition:v}=t;if(1===r){const r=A[e]>>v&1;return v-=1,v<0&&(e+=1,v=7),t.bytePosition=e,t.bitPosition=v,r}let n=0;for(let t=0;t<r;t++)n<<=1,n|=A[e]>>v&1,v-=1,v<0&&(e+=1,v=7);return t.bytePosition=e,t.bitPosition=v,n}const JA={1:kA,3:class extends lA{codes={};codeBook={};sortedCodes=[];valuesByIndex=[];bitLengthsByIndex=[];bitCodeToIndex=[];constructor(A,t){if(super(A,t),!["byte","int"].includes(this.dataType))throw new TypeError(`${this.dataType} decoding not yet implemented by HUFFMAN_INT codec`);this.buildCodeBook(),this.buildCodes(),this.buildCaches(),this.sortedCodes.length>0&&0===this.sortedCodes[0].bitLength&&(this._decode=this._decodeZeroLengthCode);}buildCodeBook(){const A=new Array(this.parameters.numCodes);for(let t=0;t<this.parameters.numCodes;t++)A[t]={symbol:this.parameters.symbols[t],bitLength:this.parameters.bitLengths[t]};A.sort((A,t)=>A.bitLength-t.bitLength||A.symbol-t.symbol),this.codeBook={},A.forEach(A=>{this.codeBook[A.bitLength]||(this.codeBook[A.bitLength]=[]),this.codeBook[A.bitLength].push(A.symbol);});}buildCodes(){this.codes={};let A=0,t=-1;Object.entries(this.codeBook).forEach(([r,e])=>{const v=Number.parseInt(r,10);e.forEach(r=>{const e={bitLength:v,value:r,bitCode:0};t+=1;const n=v-A;if(t<<=n,e.bitCode=t,A+=n,function(A){let t=A-(A>>1)&1431655765;return t=(858993459&t)+(t>>2&858993459),16843009*(t+(t>>4)&252645135)>>24}(t)>v)throw new nA("Symbol out of range");this.codes[r]=e;});});}buildCaches(){if(this.sortedCodes=Object.values(this.codes).sort((A,t)=>A.bitLength-t.bitLength||A.bitCode-t.bitCode),this.valuesByIndex=this.sortedCodes.map(A=>A.value),this.bitLengthsByIndex=this.sortedCodes.map(A=>A.bitLength),this.sortedCodes.length>0){let A=0;for(const t of this.sortedCodes)t.bitCode>A&&(A=t.bitCode);this.bitCodeToIndex=new Array(A+1).fill(-1);for(let A=0;A<this.sortedCodes.length;A++)this.bitCodeToIndex[this.sortedCodes[A].bitCode]=A;}}decode(A,t,r,e){return this._decode(A,t,e.coreBlock)}_decodeZeroLengthCode(){return this.sortedCodes[0].value}_decode(A,t,r){const e=t.content;let v=0,n=0;for(let A=0;A<this.sortedCodes.length;A+=1){const t=this.sortedCodes[A].bitLength,j=t-v;j>0&&(n<<=j,n|=LA(e,r,j)),v=t;const f=this.bitCodeToIndex[n]??-1;if(f>-1&&this.bitLengthsByIndex[f]===t)return this.valuesByIndex[f];for(;A+1<this.sortedCodes.length&&this.sortedCodes[A+1].bitLength===t;)A+=1;}throw new nA("Huffman symbol not found.")}},4:class extends lA{instantiateCodec;_lengthCodecCache;_dataCodecCache;constructor(A,t,r){super(A,t),this.instantiateCodec=r;}decode(A,t,r,e){const v=this._getLengthCodec().decode(A,t,r,e);if(v>0){const n=this._getDataCodec(),j=n.getBytesSubarray(r,e,v);if(j)return j;{const j=new Uint8Array(v);for(let f=0;f<v;f+=1)j[f]=n.decode(A,t,r,e);return j}}return new Uint8Array(0)}_getLengthCodec(){return this._lengthCodecCache??=this.instantiateCodec(this.parameters.lengthsEncoding,"int"),this._lengthCodecCache}_getDataCodec(){return this._dataCodecCache??=this.instantiateCodec(this.parameters.valuesEncoding,"byte"),this._dataCodecCache}},5:hA,6:class extends lA{constructor(A,t){if(super(A,t),"int"!==this.dataType)throw new vA(`${this.dataType} decoding not yet implemented by BETA codec`)}decode(A,t,r,e){return function(A,t,r,e){let{bytePosition:v,bitPosition:n}=t;if(8===r&&7===n){const r=A[v];return t.bytePosition=v+1,r-e}let j=0;for(let t=0;t<r;t++)j<<=1,j|=A[v]>>n&1,n-=1,n<0&&(v+=1,n=7);return t.bytePosition=v,t.bitPosition=n,j-e}(t.content,e.coreBlock,this.parameters.length,this.parameters.offset)}},7:class extends lA{constructor(A,t){if(super(A,t),"int"!==this.dataType)throw new vA(`${this.dataType} decoding not yet implemented by SUBEXP codec`)}decode(A,t,r,e){return function(A,t,r,e){let{bytePosition:v,bitPosition:n}=t,j=0;for(;;){const t=A[v]>>n&1;if(n-=1,n<0&&(v+=1,n=7),0===t)break;j+=1;}const f=0===j?r:j+r-1;let s=0;for(let t=0;t<f;t++)s<<=1,s|=A[v]>>n&1,n-=1,n<0&&(v+=1,n=7);return t.bytePosition=v,t.bitPosition=n,(0===j?s:1<<f|s)-e}(t.content,e.coreBlock,this.parameters.K,this.parameters.offset)}},9:class extends lA{constructor(A,t){if(super(A,t),"int"!==this.dataType)throw new vA(`${this.dataType} decoding not yet implemented by GAMMA codec`)}decode(A,t,r,e){return function(A,t,r){let{bytePosition:e,bitPosition:v}=t,n=1;for(;;){if(e>=A.length)throw new fA("read beyond end of core block; file seems truncated");const t=A[e]>>v&1;if(v-=1,v<0&&(e+=1,v=7),1===t)break;n+=1;}let j=0;const f=n-1;if(f>0)for(let t=0;t<f;t++)j<<=1,j|=A[e]>>v&1,v-=1,v<0&&(e+=1,v=7);return t.bytePosition=e,t.bitPosition=v,(j|1<<n-1)-r}(t.content,e.coreBlock,this.parameters.offset)}}};function _A(A,t){const r=(e="ignore"===t?0:A.codecId,JA[e]);var e;if(!r)throw new vA(`no codec implemented for codec ID ${A.codecId}`);return new r(A.parameters,t,_A)}const PA={BF:"int",CF:"int",RI:"int",RL:"int",AP:"int",RG:"int",MF:"int",NS:"int",NP:"int",TS:"int",NF:"int",TC:"byte",TN:"int",FN:"int",FC:"byte",FP:"int",BS:"byte",IN:"byteArray",SC:"byteArray",DL:"int",BA:"byte",BB:"byteArray",RS:"int",PD:"int",HC:"int",MQ:"int",RN:"byteArray",QS:"byte",QQ:"byteArray",TL:"int"},$A=[["C","G","T","N"],["A","G","T","N"],["A","C","T","N"],["A","C","G","N"],["A","C","G","T"]];class YA{readNamesIncluded;APdelta;referenceRequired;tagIdsDictionary;substitutionMatrix;dataSeriesCodecCache={};tagCodecCache={};tagEncoding={};dataSeriesEncoding;constructor(A){this.readNamesIncluded=A.preservation.RN??!1,this.APdelta=A.preservation.AP??!0,this.referenceRequired=A.preservation.RR??!0,this.tagIdsDictionary=A.preservation.TD,this.substitutionMatrix=function(A){const t=new Array(5);for(let r=0;r<5;r++){const e=new Array(4),v=A[r],n=$A[r];for(let A=0;A<4;A++)e[v>>6-2*A&3]=n[A];t[r]=e;}return t}(A.preservation.SM),this.dataSeriesEncoding=A.dataSeriesEncoding,this.tagEncoding=A.tagEncoding;}getCodecForTag(A){if(!this.tagCodecCache[A]){const t=this.tagEncoding[A];if(!t)throw new Error("Error, no tag encoding");this.tagCodecCache[A]=_A(t,"byteArray");}return this.tagCodecCache[A]}getTagNames(A){return this.tagIdsDictionary[A]}getCodecForDataSeries(A){let t=this.dataSeriesCodecCache[A];if(void 0===t){const r=this.dataSeriesEncoding[A];r&&(t=_A(r,PA[A]),this.dataSeriesCodecCache[A]=t);}return t}toJSON(){const A={};return Object.keys(this).forEach(t=>{t.endsWith("Cache")||(A[t]=this[t]);}),A}}const TA=new Uint8Array(0);function UA(A,t,r,e){const v=!!(e.mate||void 0!==e.mateRecordNumber&&e.mateRecordNumber!==t);if(!r.readName){const A=String(r.uniqueId);r._syntheticReadName=A,e._syntheticReadName=A;}r.mate={sequenceId:e.sequenceId,alignmentStart:e.alignmentStart,uniqueId:e.uniqueId},e.readName&&(r.mate.readName=e.readName),e.mate||void 0!==e.mateRecordNumber||(e.mate={sequenceId:r.sequenceId,alignmentStart:r.alignmentStart,uniqueId:r.uniqueId},r.readName&&(e.mate.readName=r.readName)),r.flags|=j,e.flags&s&&(r.flags|=b),r.flags&s&&(e.flags|=b),e.flags&i&&(r.flags|=o),r.flags&i&&(e.flags|=o),void 0===r.templateLength&&(v?function(A,t,r){const e=[r];let v=r;for(;void 0!==v.mateRecordNumber&&v.mateRecordNumber>=0;){const t=A[v.mateRecordNumber];if(!t)throw new nA("intra-slice mate record not found, this file seems malformed");e.push(t),v=t;}let n=e[0].alignmentStart,j=n+e[0].readLength-1;for(let A=1;A<e.length;A++){const t=e[A];t.alignmentStart<n&&(n=t.alignmentStart);const r=t.alignmentStart+t.readLength-1;r>j&&(j=r);}const f=j-n+1;f>=0&&e.forEach(A=>{if(void 0!==A.templateLength)throw new nA("mate pair group has some members that have template lengths already, this file seems malformed");A.templateLength=A.alignmentStart===n?f:-f;});}(A,0,r):function(A,t){const r=Math.min(A.alignmentStart,t.alignmentStart),e=Math.max(A.alignmentStart+A.readLength-1,t.alignmentStart+t.readLength-1)-r+1;A.templateLength=A.alignmentStart<=t.alignmentStart?e:-e,t.templateLength=t.alignmentStart<=A.alignmentStart?e:-e;}(r,e)),r.mateRecordNumber=void 0;}class zA{file;container;containerPosition;sliceSize;_headerResult;_blocksResult;_blocksContentIdIndexResult;constructor(A,t,r){this.file=A.file,this.container=A,this.containerPosition=t,this.sliceSize=r;}getHeader(){return void 0===this._headerResult&&(this._headerResult=this._fetchHeader(),this._headerResult.catch(()=>{this._headerResult=void 0;})),this._headerResult}async _fetchHeader(){const{majorVersion:A}=await this.file.getDefinition(),t=KA(A),r=await this.container.getHeader(),e=await this.file.readBlock(r._endPosition+this.containerPosition),v="MAPPED_SLICE_HEADER"===e.contentType?t.cramMappedSliceHeader.parser:"UNMAPPED_SLICE_HEADER"===e.contentType?t.cramUnmappedSliceHeader.parser:void 0;if(v){const A=m(e.content,v,0,r._endPosition);return {...e,parsedContent:A}}throw new nA(`error reading slice header block, invalid content type ${e.contentType}`)}getBlocks(){return void 0===this._blocksResult&&(this._blocksResult=this._fetchBlocks(),this._blocksResult.catch(()=>{this._blocksResult=void 0;})),this._blocksResult}async _fetchBlocks(){const A=await this.getHeader();if(this.sliceSize){const t=(await this.container.getHeader())._endPosition+this.containerPosition,r=A._endPosition,e=r-t,v=this.sliceSize-e,n=await this.file.read(v,r),j=new Array(A.parsedContent.numBlocks);let f=0;for(let A=0;A<j.length;A++){const t=await this.file.readBlockFromBuffer(n,f,r+f);j[A]=t,f=t._endPosition-r;}return j}let t=A._endPosition;const r=new Array(A.parsedContent.numBlocks);for(let A=0;A<r.length;A++){const e=await this.file.readBlock(t);r[A]=e,t=e._endPosition;}return r}async getCoreDataBlock(){return (await this.getBlocks())[0]}_getBlocksContentIdIndex(){return void 0===this._blocksContentIdIndexResult&&(this._blocksContentIdIndexResult=this._fetchBlocksContentIdIndex(),this._blocksContentIdIndexResult.catch(()=>{this._blocksContentIdIndexResult=void 0;})),this._blocksContentIdIndexResult}async _fetchBlocksContentIdIndex(){const A=await this.getBlocks(),t={};return A.forEach(A=>{"EXTERNAL_DATA"===A.contentType&&(t[A.contentId]=A);}),t}async getBlockByContentId(A){return (await this._getBlocksContentIdIndex())[A]}async getReferenceRegion(){const A=(await this.getHeader()).parsedContent;if(!wA(A))throw new Error("slice header not mapped");if(A.refSeqId<0)return;const t=await this.container.getCompressionScheme();if(void 0===t)throw new Error("compression scheme undefined");if(A.refBaseBlockId>=0){const t=await this.getBlockByContentId(A.refBaseBlockId);if(!t)throw new nA("embedded reference specified, but reference block does not exist");return {seq:B(t.content),start:A.refSeqStart,end:A.refSeqStart+A.refSeqSpan-1,span:A.refSeqSpan}}if(t.referenceRequired||this.file.fetchReferenceSequenceCallback){if(!this.file.fetchReferenceSequenceCallback)throw new Error("reference sequence not embedded, and seqFetch callback not provided, cannot fetch reference sequence");const t=await this.file.fetchReferenceSequenceCallback(A.refSeqId,A.refSeqStart,A.refSeqStart+A.refSeqSpan-1);if(t.length!==A.refSeqSpan)throw new jA("seqFetch callback returned a reference sequence of the wrong length");return {seq:t,start:A.refSeqStart,end:A.refSeqStart+A.refSeqSpan-1,span:A.refSeqSpan}}}getAllRecords(){return this.getRecords(()=>!0)}async _fetchRecords(A){const{majorVersion:t}=await this.file.getDefinition(),r=await this.container.getCompressionScheme();if(void 0===r)throw new Error("compression scheme undefined");const e=await this.getHeader(),v=await this._getBlocksContentIdIndex();if(t>1&&this.file.options.checkSequenceMD5&&wA(e.parsedContent)&&e.parsedContent.refSeqId>=0&&"0000000000000000"!==e.parsedContent.md5?.join("")){const A=await this.getReferenceRegion();if(A){const{seq:t,start:r,end:v}=A,n=function(A){return l(A.toUpperCase().replaceAll(/[^\u0021-\u007e]/g,""))}(t),j=e.parsedContent.md5?.map(A=>(A<16?"0":"")+A.toString(16)).join("");if(n!==j)throw new nA(`MD5 checksum reference mismatch for ref ${e.parsedContent.refSeqId} pos ${r}..${v}. recorded MD5: ${j}, calculated MD5: ${n}`)}}const n=await this.getCoreDataBlock(),j=new Map,f={lastAlignmentStart:wA(e.parsedContent)?e.parsedContent.refSeqStart:0,coreBlock:{bitPosition:7,bytePosition:0},externalBlocks:{getCursor(A){let t=j.get(A);return void 0===t&&(t={bitPosition:7,bytePosition:0},j.set(A,t)),t}}},s=new Set,b=new Set;function i(A,t){A&&(1===A.codecId?t?s.add(A.parameters.blockContentId):b.add(A.parameters.blockContentId):4===A.codecId?(i(A.parameters.lengthsEncoding,!0),i(A.parameters.valuesEncoding,!1)):5===A.codecId&&b.add(A.parameters.blockContentId));}for(const[A,t]of Object.entries(r.dataSeriesEncoding))i(t,"int"===PA[A]);for(const A of Object.values(r.tagEncoding))i(A,!1);for(const A of b)s.delete(A);const o=new Map;for(const A of s){const t=v[A];if(t?.content.length){const r=dA(t.content);o.set(A,{values:r,index:0});}}f.preDecodedIntBlocks=o;const a=A=>{const t=r.getCodecForDataSeries(A);if(!t)return ()=>{throw new nA(`no codec defined for ${A} data series`)};if(t instanceof kA){const A=t.parameters.blockContentId,r=o.get(A);if(r){const{values:A}=r;return ()=>A[r.index++]}const e=v[A];if(!e)return ()=>{throw new nA(`no block found with content ID ${A}`)};const n=f.externalBlocks.getCursor(A),j=e.content;return "int"===t.dataType?()=>u(j,n):()=>{if(n.bytePosition>=j.length)throw new fA("attempted to read beyond end of block. this file seems truncated.");return j[n.bytePosition++]}}if(t instanceof hA){const{blockContentId:A,stopByte:r}=t.parameters,e=v[A];if(!e)return ()=>{throw new nA(`no block found with content ID ${A}`)};const n=e.content,j=f.externalBlocks.getCursor(A);return ()=>{const A=j.bytePosition,t=n.length;let e=A;for(;e<t&&n[e]!==r;)e++;if(e>=t)throw new fA("byteArrayStop reading beyond length of data buffer?");return j.bytePosition=e+1,n.subarray(A,e)}}return ()=>t.decode(this,n,v,f)},g={BF:a("BF"),CF:a("CF"),RI:a("RI"),RL:a("RL"),AP:a("AP"),RG:a("RG"),RN:a("RN"),MF:a("MF"),NS:a("NS"),NP:a("NP"),TS:a("TS"),NF:a("NF"),TL:a("TL"),FN:a("FN"),FC:a("FC"),FP:a("FP"),DL:a("DL"),BB:a("BB"),QQ:a("QQ"),BS:a("BS"),IN:a("IN"),RS:a("RS"),PD:a("PD"),HC:a("HC"),SC:a("SC"),MQ:a("MQ"),BA:a("BA"),QS:a("QS"),TC:a("TC"),TN:a("TN")},I=r.getCodecForDataSeries("QS"),c=r.getCodecForDataSeries("BA"),C=I||c?(A,t)=>{const r="QS"===A?I:c;return r?.getBytesSubarray(v,f,t)}:void 0,E={},h=A=>{const t=r.getCodecForTag(A);return ()=>t.decode(this,n,v,f)};for(const A of Object.keys(r.tagEncoding)){const t=r.tagEncoding[A];if(4===t.codecId&&1===t.parameters.lengthsEncoding.codecId&&1===t.parameters.valuesEncoding.codecId){const r=t.parameters.lengthsEncoding.parameters.blockContentId,e=t.parameters.valuesEncoding.parameters.blockContentId,n=v[r],j=v[e];if(!n||!j){E[A]=h(A);continue}const s=j.content,b=f.externalBlocks.getCursor(e),i=o.get(r),a=n.content,g=f.externalBlocks.getCursor(r),I=i?()=>i.values[i.index++]:()=>u(a,g);E[A]=()=>{const A=I();if(0===A)return TA;const t=b.bytePosition,r=t+A;if(r>s.length)throw new fA("attempted to read beyond end of block. this file seems truncated.");return b.bytePosition=r,s.subarray(t,r)};}else E[A]=h(A);}const d=new Array(e.parsedContent.numRecords),k=function(A,t){const r=t>1?A.SC:A.IN,e=new Array(128);return e["B".charCodeAt(0)]=["B",()=>[String.fromCharCode(A.BA()),A.QS()]],e["X".charCodeAt(0)]=["X",()=>A.BS()],e["D".charCodeAt(0)]=["D",()=>A.DL()],e["I".charCodeAt(0)]=["I",()=>B(A.IN())],e["i".charCodeAt(0)]=["i",()=>String.fromCharCode(A.BA())],e["b".charCodeAt(0)]=["b",()=>B(A.BB())],e["q".charCodeAt(0)]=["q",()=>Array.from(A.QQ())],e["Q".charCodeAt(0)]=["Q",()=>A.QS()],e["H".charCodeAt(0)]=["H",()=>A.HC()],e["P".charCodeAt(0)]=["P",()=>A.PD()],e["N".charCodeAt(0)]=["N",()=>A.RS()],e["S".charCodeAt(0)]=["S",()=>B(r())],e}(g,t);for(let v=0;v<d.length;v+=1)try{d[v]=new R(HA(0,g,k,E,r,e,0,0,f,t,v,e.contentPosition+e.parsedContent.recordCounter+v+1,A,C));}catch(A){const t=A;if("CRAM_BUFFER_OVERRUN"===t.code){const A=v,r=e.parsedContent.numRecords;throw new nA(`Failed to decode all records in slice. Decoded ${A} of ${r} expected records. Buffer overrun suggests either: (1) file is truncated/corrupted, (2) compression scheme is incorrect, or (3) there's a bug in the decoder. Original error: ${t.message}`)}throw A}for(let A=0;A<d.length;A+=1){const t=d[A],{mateRecordNumber:r}=t;void 0!==r&&r>=0&&d[r]&&UA(d,A,t,d[r]);}return d}async getRecords(A,t){const r={...w,...t},e=""+(r.decodeTags?1:0),v=`${this.container.filePosition}:${this.containerPosition}:${e}`;let n=this.file.featureCache.get(v);n||(n=this._fetchRecords(r),this.file.featureCache.set(v,n));const j=(await n).filter(A);if(j.length&&this.file.fetchReferenceSequenceCallback){const A=await this.getHeader();if(wA(A.parsedContent)&&(A.parsedContent.refSeqId>=0||-2===A.parsedContent.refSeqId)){const t=A.parsedContent.refSeqId>=0?A.parsedContent.refSeqId:void 0,r=await this.container.getCompressionScheme();if(void 0===r)throw new Error("compression scheme undefined");const e={};for(const A of j){const r=void 0!==t?t:A.sequenceId;let v=e[r];v||(v={id:r,start:A.alignmentStart,end:Number.NEGATIVE_INFINITY,seq:null},e[r]=v);const n=A.alignmentStart+(A.lengthOnRef||A.readLength)-1;n>v.end&&(v.end=n),A.alignmentStart<v.start&&(v.start=A.alignmentStart);}await Promise.all(Object.values(e).map(async A=>{-1!==A.id&&A.start<=A.end&&this.file.fetchReferenceSequenceCallback&&(A.seq=await this.file.fetchReferenceSequenceCallback(A.id,A.start,A.end));}));for(const A of j){const v=e[void 0!==t?t:A.sequenceId];if(v?.seq){const t=v.seq;A.addReferenceSequence({...v,seq:t},r);}}}}return j}}class VA{file;filePosition;_headerResult;_compressionHeaderBlockResult;_compressionSchemeResult;constructor(A,t){this.file=A,this.filePosition=t;}getHeader(){return void 0===this._headerResult&&(this._headerResult=this._fetchHeader(),this._headerResult.catch(()=>{this._headerResult=void 0;})),this._headerResult}_fetchHeader(){return this._readContainerHeader(this.filePosition)}async getCompressionHeaderBlock(){return void 0===this._compressionHeaderBlockResult&&(this._compressionHeaderBlockResult=this._fetchCompressionHeaderBlock(),this._compressionHeaderBlockResult.catch(()=>{this._compressionHeaderBlockResult=void 0;})),this._compressionHeaderBlockResult}async _fetchCompressionHeaderBlock(){if(!(await this.getHeader()).numRecords)return null;const{majorVersion:A}=await this.file.getDefinition(),t=KA(A),r=await this.getFirstBlock();if("COMPRESSION_HEADER"!==r.contentType)throw new nA(`invalid content type ${r.contentType} in compression header block`);const e=m(r.content,t.cramCompressionHeader.parser,0,r.contentPosition);return {...r,parsedContent:e}}async getFirstBlock(){const A=await this.getHeader();return this.file.readBlock(A._endPosition)}async getCompressionScheme(){return void 0===this._compressionSchemeResult&&(this._compressionSchemeResult=this._fetchCompressionScheme(),this._compressionSchemeResult.catch(()=>{this._compressionSchemeResult=void 0;})),this._compressionSchemeResult}async _fetchCompressionScheme(){const A=await this.getCompressionHeaderBlock();if(A)return new YA(A.parsedContent)}getSlice(A,t){return new zA(this,A,t)}async _readContainerHeader(A){const{majorVersion:t}=await this.file.getDefinition(),r=KA(t),{cramContainerHeader1:e,cramContainerHeader2:v}=r,n=m(await this.file.read(e.maxLength,A),e.parser),j=-128&(f=n.numLandmarks)?-16384&f?-2097152&f?-268435456&f?5:4:3:2:1;var f;const s=m(await this.file.read(v.maxLength(n.numLandmarks),A+n._size-j),v.parser);return this.file.validateChecksums&&void 0!==s.crc32&&await this.file.checkCrc32(A,n._size+s._size-j-4,s.crc32,`container header beginning at position ${A}`),{...n,...s,_size:n._size+s._size-j,_endPosition:n._size+s._size-j+A}}}class XA{exports;memory;ptr;bufSize;inStart;outStart;mem8;mem32;constructor(A){this.exports=A.exports,this.memory=this.exports.memory,this.ptr=this.exports.create_context(),this._refresh(),this.bufSize=this.mem32[0],this.inStart=this.mem32[1]-this.ptr,this.outStart=this.mem32[4]-this.ptr;}supplyInput(A){this._refresh(),this.mem8.subarray(this.inStart,this.inStart+this.bufSize).set(A,0),this.exports.supply_input(this.ptr,A.byteLength);}getNextOutput(){const A=this.exports.get_next_output(this.ptr);if(this._refresh(),0!==A&&1!==A)throw new Error(`get_next_output failed with error code ${A}`);return {outChunk:this.mem8.slice(this.outStart,this.outStart+this.mem32[5]),finished:1===A}}dispose(){this.exports.destroy_context(this.ptr);}_refresh(){const A=this.memory.buffer;A!==this.mem8?.buffer&&(this.mem8=new Uint8Array(A,this.ptr),this.mem32=new Uint32Array(A,this.ptr));}}let WA,ZA;const At=new Uint8Array(0);let tt;class rt{file;validateChecksums;fetchReferenceSequenceCallback;options;featureCache;header;_sectionParsers;_definitionResult;_samHeaderResult;constructor(A){if(this.file=CA(A.url,A.path,A.filehandle),this.validateChecksums=A.validateChecksums??!1,this.fetchReferenceSequenceCallback=A.seqFetch,this.options={checkSequenceMD5:A.checkSequenceMD5,cacheSize:A.cacheSize??2e4},this.featureCache=new AA({maxSize:this.options.cacheSize}),void 0===tt&&(tt=68===new Uint8Array(new Uint32Array([287454020]).buffer)[0]),!tt)throw new Error("Detected big-endian machine, may be unable to run")}read(A,t){return this.file.read(A,t)}async _getSectionParsers(){if(!this._sectionParsers){const{majorVersion:A}=await this.getDefinition();this._sectionParsers=KA(A);}return this._sectionParsers}async getDefinition(){return void 0===this._definitionResult&&(this._definitionResult=this._fetchDefinition(),this._definitionResult.catch(()=>{this._definitionResult=void 0;})),this._definitionResult}async _fetchDefinition(){const{maxLength:A,parser:t}=QA(),r=t(await this.file.read(A,0)).value;if("CRAM"!==r.magic)throw new Error("Not a CRAM file, does not match magic string");if(2!==r.majorVersion&&3!==r.majorVersion)throw new vA(`CRAM version ${r.majorVersion} not supported`);return r}async getSamHeader(){return void 0===this._samHeaderResult&&(this._samHeaderResult=this._fetchSamHeader(),this._samHeaderResult.catch(()=>{this._samHeaderResult=void 0;})),this._samHeaderResult}async _fetchSamHeader(){const A=await this.getContainerById(0);if(!A)throw new nA("file contains no containers");const t=(await A.getFirstBlock()).content,r=new DataView(t.buffer,t.byteOffset,t.byteLength).getInt32(0,!0),e=B(t.subarray(4,4+r));return this.header=e,function(A){const t=A.split(/\r?\n/),r=[];for(const A of t){const[t,...e]=A.split(/\t/);t&&r.push({tag:t.slice(1),data:e.map(A=>{const t=A.indexOf(":");return -1!==t?{tag:A.slice(0,t),value:A.slice(t+1)}:{tag:A,value:""}})});}return r}(e)}async getHeaderText(){return await this.getSamHeader(),this.header}async*iterContainers(){let A=(await this._getSectionParsers()).cramFileDefinition.maxLength,t=0;for(;;){const r=this.getContainerAtPosition(A),e=await r.getHeader();if(yield r,0===t){A=e._endPosition;for(let t=0;t<e.numBlocks;t++)A=(await this.readBlock(A))._endPosition;}else A+=e._size+e.length;t++;}}async getContainerById(A){let t=0;for await(const r of this.iterContainers()){if(t===A)return r;t++;}}async checkCrc32(A,t,r,e){const v=await this.file.read(t,A),n=rA(v)>>>0;if(n!==r)throw new nA(`crc mismatch in ${e}: recorded CRC32 = ${r}, but calculated CRC32 = ${n}`)}async containerCount(){let A=0;try{for await(const t of this.iterContainers())A+=1;}catch(t){A--;}return A}getContainerAtPosition(A){return new VA(this,A)}async readBlockHeader(A){const{cramBlockHeader:t}=await this._getSectionParsers();return m(await this.file.read(t.maxLength,A),t.parser,0,A)}async _parseSection(A,t,r=A.maxLength,e){const v=m(e??await this.file.read(r,t),A.parser,0,t);if(v._size!==r)throw new nA(`section read error: requested size ${r} does not equal parsed size ${v._size}`);return v}async _uncompress(A,t,r){let e;if("gzip"===A)e=await EA(t);else if("bzip2"===A)e=await(v=t,n=r,aA(v,"bz2_uncompress",(A,t,r)=>A._bz2_uncompress(t,v.length,n,r),!0));else if("lzma"===A)e=await async function(A){ZA||await(WA||(WA=async function(){const 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".replace("data:application/wasm;base64,",""),t=atob(A),r=t.length,e=new Uint8Array(r);for(let A=0;A<r;A++)e[A]=t.charCodeAt(A);const v=await WebAssembly.instantiate(e.buffer,{});ZA=v.instance;}()));const t=new XA(ZA),r=[];let e=0,v=!1;try{for(;;){if(t.mem32[2]===t.mem32[3])if(e<A.length){const r=Math.min(t.bufSize,A.length-e);t.supplyInput(A.subarray(e,e+r)),e+=r;}else {if(v)throw new Error("XZ decompression error: unexpected end of input");t.supplyInput(At),v=!0;}const n=t.getNextOutput();if(n.outChunk.length>0&&r.push(n.outChunk),t.mem32[5]=0,n.finished)break}if(1===r.length)return r[0];const n=r.reduce((A,t)=>A+t.length,0),j=new Uint8Array(n);let f=0;for(const A of r)j.set(A,f),f+=A.length;return j}finally{t.dispose();}}(t);else if("rans"===A)e=await function(A){return aA(A,"rans_uncompress",(t,r,e)=>t._rans_uncompress(r,A.length,e),!0)}(t);else if("rans4x16"===A)e=await function(A){return aA(A,"rans_uncompress_4x16",(t,r,e)=>t._rans_uncompress_4x16(r,A.length,e))}(t);else if("arith"===A)e=await function(A){return aA(A,"arith_uncompress",(t,r,e)=>t._arith_uncompress(r,A.length,e))}(t);else if("fqzcomp"===A)e=await async function(A){const t=await oA(),r=t._malloc(4);try{return await aA(A,"fqz_decompress",(t,e,v)=>t._fqz_decompress(e,A.length,v,r))}finally{t._free(r);}}(t);else {if("tok3"!==A)throw new vA(`${A} decompression not yet implemented`);e=await function(A){return aA(A,"tok3_decode_names",(t,r,e)=>t._tok3_decode_names(r,A.length,e))}(t);}var v,n;if(e.length!==r)throw new nA(`${A} decompression produced ${e.length} bytes, expected ${r}`);return e}async readBlock(A){const{majorVersion:t}=await this.getDefinition(),{cramBlockHeader:r,cramBlockCrc32:e}=await this._getSectionParsers(),v=m(await this.file.read(r.maxLength,A),r.parser,0,A),n=v._size+v.compressedSize+(t>=3?e.maxLength:0),j=await this.file.read(n,A);return this.readBlockFromBuffer(j,0,A)}async readBlockFromBuffer(A,t,r){const{majorVersion:e}=await this.getDefinition(),v=await this._getSectionParsers(),{cramBlockHeader:n}=v,j=m(A.subarray(t,t+n.maxLength),n.parser,0,r),f=j._endPosition,s=t+j._size,b=A.subarray(s,s+j.compressedSize),i=0===j.uncompressedSize?new Uint8Array(0):"raw"!==j.compressionMethod?await this._uncompress(j.compressionMethod,b,j.uncompressedSize):b,o={...j,_endPosition:f,contentPosition:f,content:i};if(e>=3){const r=s+j.compressedSize,e=m(A.subarray(r,r+v.cramBlockCrc32.maxLength),v.cramBlockCrc32.parser,0,f+j.compressedSize);if(o.crc32=e.crc32,this.validateChecksums){const r=A.subarray(t,t+j._size+j.compressedSize),v=rA(r)>>>0;if(v!==e.crc32)throw new nA(`crc mismatch in block data: recorded CRC32 = ${e.crc32}, but calculated CRC32 = ${v}`)}o._endPosition=e._endPosition,o._size=o.compressedSize+v.cramBlockCrc32.maxLength;}else o._endPosition=f+o.compressedSize,o._size=o.compressedSize;return o}}function et(A,t){const[r,e,v,n,j,f]=t,s=r;A[s]||(A[s]=[]),A[s].push({start:e,span:v,containerStart:n,sliceStart:j,sliceBytes:f});}class vt{parseIndexP;filehandle;constructor(A){this.filehandle=CA(A.url,A.path,A.filehandle);}async parseIndex(){const A={},t=await async function(A){return 31===A[0]&&139===A[1]?EA(A):A}(await this.filehandle.readFile()),r=new DataView(t.buffer,t.byteOffset,t.byteLength);if(t.length>4&&21578050===r.getUint32(0,!0))throw new nA("invalid .crai index file. note: file appears to be a .bai index. this is technically legal but please open a github issue if you need support");let e=[],v="";for(const r of t)if(r>=48&&r<=57||!v&&45===r)v+=String.fromCharCode(r);else if(9===r)e.push(Number.parseInt(v,10)),v="";else if(10===r)e.push(Number.parseInt(v,10)),v="",et(A,e),e=[];else if(13!==r&&32!==r)throw new nA("invalid .crai index file");v&&e.push(Number.parseInt(v,10)),6===e.length&&et(A,e);for(const t of Object.values(A))t?.sort((A,t)=>A.start-t.start||A.span-t.span);return A}getIndex(){return this.parseIndexP||(this.parseIndexP=this.parseIndex().catch(A=>{throw this.parseIndexP=void 0,A})),this.parseIndexP}async hasDataForReferenceSequence(A){return !!(await this.getIndex())[A]}async getEntriesForRange(A,t,r){const e=(await this.getIndex())[A];return e?e.filter(A=>A.start<=r&&A.start+A.span>t):[]}}function nt(A){const t=A.readName;if(void 0===t)throw new Error("readName undefined");return t}class jt{cram;index;constructor(A){this.cram=A.cram??new rt({url:A.cramUrl,path:A.cramPath,filehandle:A.cramFilehandle,seqFetch:A.seqFetch,checkSequenceMD5:A.checkSequenceMD5,validateChecksums:A.validateChecksums,cacheSize:A.cacheSize}),this.index=A.index;}async getRecordsForRange(A,t,r,e={}){const v=e.viewAsPairs??!1,n=e.pairAcrossChr??!1,j=e.maxInsertSize??2e5,f=e.onProgress,s={decodeTags:e.decodeTags},b=A,i=await this.index.getEntriesForRange(b,t,r);let o=0;for(const A of i)o+=A.sliceBytes;let a=0;f?.(0,o);let g=(await Promise.all(i.map(e=>this.getRecordsInSlice(e,e=>e.sequenceId===A&&(void 0===e.lengthOnRef?e.alignmentStart>=t&&e.alignmentStart<=r:e.alignmentStart<=r&&e.alignmentStart+e.lengthOnRef-1>t),s).then(A=>(a+=e.sliceBytes,f?.(a,o),A))))).flat();if(v){const A={},t=new Set;for(const r of g){const e=nt(r);A[e]=(A[e]??0)+1,t.add(r.uniqueId);}const r=new Set(Object.keys(A).filter(t=>1===A[t])),e=[];for(const A of g){const t=nt(A);r.has(t)&&A.mate&&(A.mate.sequenceId===b||n)&&Math.abs(A.alignmentStart-A.mate.alignmentStart)<j&&e.push(this.index.getEntriesForRange(A.mate.sequenceId,A.mate.alignmentStart,A.mate.alignmentStart+1));}const v=await Promise.all(e),f=new Map;for(const A of v.flat())f.set(`${A.containerStart}:${A.sliceStart}:${A.sliceBytes}`,A);const s=[...f.values()].map(A=>this.getRecordsInSlice(A,()=>!0).then(A=>{const e=[];for(const v of A){const A=nt(v);r.has(A)&&!t.has(v.uniqueId)&&e.push(v);}return e})),i=await Promise.all(s);g=g.concat(i.flat());}return g}getRecordsInSlice({containerStart:A,sliceStart:t,sliceBytes:r},e,v){return this.cram.getContainerAtPosition(A).getSlice(t,r).getRecords(e,v)}hasDataForReferenceSequence(A){return this.index.hasDataForReferenceSequence(A)}}})(),gmodCRAM=e;})();
+var gmodCRAM$1 = gmodCRAM;
 
 class FileHandler {
 
@@ -52640,7 +52699,7 @@ class CramReader {
         this.browser = browser;
         this.genome = genome;
 
-        this.cramFile = new gmodCRAM.CramFile({
+        this.cramFile = new gmodCRAM$1.CramFile({
             filehandle: config.fileHandle ? config.fileHandle : new FileHandler(config.url, config),
             //url: config.url,
             seqFetch: config.seqFetch || seqFetch.bind(this),
@@ -52648,9 +52707,9 @@ class CramReader {
         });
 
         const indexFileHandle = config.indexFileHandle ? config.indexFileHandle : new FileHandler(config.indexURL, config);
-        this.indexedCramFile = new gmodCRAM.IndexedCramFile({
+        this.indexedCramFile = new gmodCRAM$1.IndexedCramFile({
             cram: this.cramFile,
-            index: new gmodCRAM.CraiIndex({
+            index: new gmodCRAM$1.CraiIndex({
                 //url: config.indexURL
                 filehandle: indexFileHandle
             }),
@@ -52775,6 +52834,9 @@ class CramReader {
 
                     const alignment = decodeCramRecord(record, header.chrNames);
 
+                    // Convert qual to regular array -- this was a breaking change somewhere between 5.X and 8.3.0
+                    if(alignment.qual) alignment.qual = Array.from(alignment.qual);
+
                     if (this.filter.pass(alignment)) {
                         alignmentContainer.push(alignment);
                     }
@@ -77536,7 +77598,7 @@ function createReferenceFrameList(loci, genome, browserFlanking, minimumBases, v
     })
 }
 
-const _version = "3.8.2";
+const _version = "3.8.4";
 function version() {
     return _version
 }