igv 3.5.0 → 3.5.2

package/dist/igv.js

@@ -10524,6 +10524,7 @@
    function createColumn(columnContainer, className) {
        const column = div({class: className});
        columnContainer.appendChild(column);
+       return column
    }
 
 
@@ -10744,7 +10745,7 @@
        return list;
    }
 
-   /*! @license DOMPurify 3.2.6 | (c) Cure53 and other contributors | Released under the Apache license 2.0 and Mozilla Public License 2.0 | github.com/cure53/DOMPurify/blob/3.2.6/LICENSE */
+   /*! @license DOMPurify 3.2.7 | (c) Cure53 and other contributors | Released under the Apache license 2.0 and Mozilla Public License 2.0 | github.com/cure53/DOMPurify/blob/3.2.7/LICENSE */
 
    const {
      entries,
@@ -10773,12 +10774,18 @@
      };
    }
    if (!apply) {
-     apply = function apply(fun, thisValue, args) {
-       return fun.apply(thisValue, args);
+     apply = function apply(func, thisArg) {
+       for (var _len = arguments.length, args = new Array(_len > 2 ? _len - 2 : 0), _key = 2; _key < _len; _key++) {
+         args[_key - 2] = arguments[_key];
+       }
+       return func.apply(thisArg, args);
      };
    }
    if (!construct) {
-     construct = function construct(Func, args) {
+     construct = function construct(Func) {
+       for (var _len2 = arguments.length, args = new Array(_len2 > 1 ? _len2 - 1 : 0), _key2 = 1; _key2 < _len2; _key2++) {
+         args[_key2 - 1] = arguments[_key2];
+       }
        return new Func(...args);
      };
    }
@@ -10807,8 +10814,8 @@
        if (thisArg instanceof RegExp) {
          thisArg.lastIndex = 0;
        }
-       for (var _len = arguments.length, args = new Array(_len > 1 ? _len - 1 : 0), _key = 1; _key < _len; _key++) {
-         args[_key - 1] = arguments[_key];
+       for (var _len3 = arguments.length, args = new Array(_len3 > 1 ? _len3 - 1 : 0), _key3 = 1; _key3 < _len3; _key3++) {
+         args[_key3 - 1] = arguments[_key3];
        }
        return apply(func, thisArg, args);
      };
@@ -10819,12 +10826,12 @@
     * @param func - The constructor function to be wrapped and called.
     * @returns A new function that constructs an instance of the given constructor function with the provided arguments.
     */
-   function unconstruct(func) {
+   function unconstruct(Func) {
      return function () {
-       for (var _len2 = arguments.length, args = new Array(_len2), _key2 = 0; _key2 < _len2; _key2++) {
-         args[_key2] = arguments[_key2];
+       for (var _len4 = arguments.length, args = new Array(_len4), _key4 = 0; _key4 < _len4; _key4++) {
+         args[_key4] = arguments[_key4];
        }
-       return construct(func, args);
+       return construct(Func, args);
      };
    }
    /**
@@ -10923,8 +10930,8 @@
      return fallbackValue;
    }
 
-   const html$1 = freeze(['a', 'abbr', 'acronym', 'address', 'area', 'article', 'aside', 'audio', 'b', 'bdi', 'bdo', 'big', 'blink', 'blockquote', 'body', 'br', 'button', 'canvas', 'caption', 'center', 'cite', 'code', 'col', 'colgroup', 'content', 'data', 'datalist', 'dd', 'decorator', 'del', 'details', 'dfn', 'dialog', 'dir', 'div', 'dl', 'dt', 'element', 'em', 'fieldset', 'figcaption', 'figure', 'font', 'footer', 'form', 'h1', 'h2', 'h3', 'h4', 'h5', 'h6', 'head', 'header', 'hgroup', 'hr', 'html', 'i', 'img', 'input', 'ins', 'kbd', 'label', 'legend', 'li', 'main', 'map', 'mark', 'marquee', 'menu', 'menuitem', 'meter', 'nav', 'nobr', 'ol', 'optgroup', 'option', 'output', 'p', 'picture', 'pre', 'progress', 'q', 'rp', 'rt', 'ruby', 's', 'samp', 'section', 'select', 'shadow', 'small', 'source', 'spacer', 'span', 'strike', 'strong', 'style', 'sub', 'summary', 'sup', 'table', 'tbody', 'td', 'template', 'textarea', 'tfoot', 'th', 'thead', 'time', 'tr', 'track', 'tt', 'u', 'ul', 'var', 'video', 'wbr']);
-   const svg$1 = freeze(['svg', 'a', 'altglyph', 'altglyphdef', 'altglyphitem', 'animatecolor', 'animatemotion', 'animatetransform', 'circle', 'clippath', 'defs', 'desc', 'ellipse', 'filter', 'font', 'g', 'glyph', 'glyphref', 'hkern', 'image', 'line', 'lineargradient', 'marker', 'mask', 'metadata', 'mpath', 'path', 'pattern', 'polygon', 'polyline', 'radialgradient', 'rect', 'stop', 'style', 'switch', 'symbol', 'text', 'textpath', 'title', 'tref', 'tspan', 'view', 'vkern']);
+   const html$1 = freeze(['a', 'abbr', 'acronym', 'address', 'area', 'article', 'aside', 'audio', 'b', 'bdi', 'bdo', 'big', 'blink', 'blockquote', 'body', 'br', 'button', 'canvas', 'caption', 'center', 'cite', 'code', 'col', 'colgroup', 'content', 'data', 'datalist', 'dd', 'decorator', 'del', 'details', 'dfn', 'dialog', 'dir', 'div', 'dl', 'dt', 'element', 'em', 'fieldset', 'figcaption', 'figure', 'font', 'footer', 'form', 'h1', 'h2', 'h3', 'h4', 'h5', 'h6', 'head', 'header', 'hgroup', 'hr', 'html', 'i', 'img', 'input', 'ins', 'kbd', 'label', 'legend', 'li', 'main', 'map', 'mark', 'marquee', 'menu', 'menuitem', 'meter', 'nav', 'nobr', 'ol', 'optgroup', 'option', 'output', 'p', 'picture', 'pre', 'progress', 'q', 'rp', 'rt', 'ruby', 's', 'samp', 'search', 'section', 'select', 'shadow', 'slot', 'small', 'source', 'spacer', 'span', 'strike', 'strong', 'style', 'sub', 'summary', 'sup', 'table', 'tbody', 'td', 'template', 'textarea', 'tfoot', 'th', 'thead', 'time', 'tr', 'track', 'tt', 'u', 'ul', 'var', 'video', 'wbr']);
+   const svg$1 = freeze(['svg', 'a', 'altglyph', 'altglyphdef', 'altglyphitem', 'animatecolor', 'animatemotion', 'animatetransform', 'circle', 'clippath', 'defs', 'desc', 'ellipse', 'enterkeyhint', 'exportparts', 'filter', 'font', 'g', 'glyph', 'glyphref', 'hkern', 'image', 'inputmode', 'line', 'lineargradient', 'marker', 'mask', 'metadata', 'mpath', 'part', 'path', 'pattern', 'polygon', 'polyline', 'radialgradient', 'rect', 'slot', 'stop', 'style', 'switch', 'symbol', 'text', 'textpath', 'title', 'tref', 'tspan', 'view', 'vkern']);
    const svgFilters = freeze(['feBlend', 'feColorMatrix', 'feComponentTransfer', 'feComposite', 'feConvolveMatrix', 'feDiffuseLighting', 'feDisplacementMap', 'feDistantLight', 'feDropShadow', 'feFlood', 'feFuncA', 'feFuncB', 'feFuncG', 'feFuncR', 'feGaussianBlur', 'feImage', 'feMerge', 'feMergeNode', 'feMorphology', 'feOffset', 'fePointLight', 'feSpecularLighting', 'feSpotLight', 'feTile', 'feTurbulence']);
    // List of SVG elements that are disallowed by default.
    // We still need to know them so that we can do namespace
@@ -10937,7 +10944,7 @@
    const mathMlDisallowed = freeze(['maction', 'maligngroup', 'malignmark', 'mlongdiv', 'mscarries', 'mscarry', 'msgroup', 'mstack', 'msline', 'msrow', 'semantics', 'annotation', 'annotation-xml', 'mprescripts', 'none']);
    const text = freeze(['#text']);
 
-   const html = freeze(['accept', 'action', 'align', 'alt', 'autocapitalize', 'autocomplete', 'autopictureinpicture', 'autoplay', 'background', 'bgcolor', 'border', 'capture', 'cellpadding', 'cellspacing', 'checked', 'cite', 'class', 'clear', 'color', 'cols', 'colspan', 'controls', 'controlslist', 'coords', 'crossorigin', 'datetime', 'decoding', 'default', 'dir', 'disabled', 'disablepictureinpicture', 'disableremoteplayback', 'download', 'draggable', 'enctype', 'enterkeyhint', 'face', 'for', 'headers', 'height', 'hidden', 'high', 'href', 'hreflang', 'id', 'inputmode', 'integrity', 'ismap', 'kind', 'label', 'lang', 'list', 'loading', 'loop', 'low', 'max', 'maxlength', 'media', 'method', 'min', 'minlength', 'multiple', 'muted', 'name', 'nonce', 'noshade', 'novalidate', 'nowrap', 'open', 'optimum', 'pattern', 'placeholder', 'playsinline', 'popover', 'popovertarget', 'popovertargetaction', 'poster', 'preload', 'pubdate', 'radiogroup', 'readonly', 'rel', 'required', 'rev', 'reversed', 'role', 'rows', 'rowspan', 'spellcheck', 'scope', 'selected', 'shape', 'size', 'sizes', 'span', 'srclang', 'start', 'src', 'srcset', 'step', 'style', 'summary', 'tabindex', 'title', 'translate', 'type', 'usemap', 'valign', 'value', 'width', 'wrap', 'xmlns', 'slot']);
+   const html = freeze(['accept', 'action', 'align', 'alt', 'autocapitalize', 'autocomplete', 'autopictureinpicture', 'autoplay', 'background', 'bgcolor', 'border', 'capture', 'cellpadding', 'cellspacing', 'checked', 'cite', 'class', 'clear', 'color', 'cols', 'colspan', 'controls', 'controlslist', 'coords', 'crossorigin', 'datetime', 'decoding', 'default', 'dir', 'disabled', 'disablepictureinpicture', 'disableremoteplayback', 'download', 'draggable', 'enctype', 'enterkeyhint', 'exportparts', 'face', 'for', 'headers', 'height', 'hidden', 'high', 'href', 'hreflang', 'id', 'inert', 'inputmode', 'integrity', 'ismap', 'kind', 'label', 'lang', 'list', 'loading', 'loop', 'low', 'max', 'maxlength', 'media', 'method', 'min', 'minlength', 'multiple', 'muted', 'name', 'nonce', 'noshade', 'novalidate', 'nowrap', 'open', 'optimum', 'part', 'pattern', 'placeholder', 'playsinline', 'popover', 'popovertarget', 'popovertargetaction', 'poster', 'preload', 'pubdate', 'radiogroup', 'readonly', 'rel', 'required', 'rev', 'reversed', 'role', 'rows', 'rowspan', 'spellcheck', 'scope', 'selected', 'shape', 'size', 'sizes', 'slot', 'span', 'srclang', 'start', 'src', 'srcset', 'step', 'style', 'summary', 'tabindex', 'title', 'translate', 'type', 'usemap', 'valign', 'value', 'width', 'wrap', 'xmlns', 'slot']);
    const svg = freeze(['accent-height', 'accumulate', 'additive', 'alignment-baseline', 'amplitude', 'ascent', 'attributename', 'attributetype', 'azimuth', 'basefrequency', 'baseline-shift', 'begin', 'bias', 'by', 'class', 'clip', 'clippathunits', 'clip-path', 'clip-rule', 'color', 'color-interpolation', 'color-interpolation-filters', 'color-profile', 'color-rendering', 'cx', 'cy', 'd', 'dx', 'dy', 'diffuseconstant', 'direction', 'display', 'divisor', 'dur', 'edgemode', 'elevation', 'end', 'exponent', 'fill', 'fill-opacity', 'fill-rule', 'filter', 'filterunits', 'flood-color', 'flood-opacity', 'font-family', 'font-size', 'font-size-adjust', 'font-stretch', 'font-style', 'font-variant', 'font-weight', 'fx', 'fy', 'g1', 'g2', 'glyph-name', 'glyphref', 'gradientunits', 'gradienttransform', 'height', 'href', 'id', 'image-rendering', 'in', 'in2', 'intercept', 'k', 'k1', 'k2', 'k3', 'k4', 'kerning', 'keypoints', 'keysplines', 'keytimes', 'lang', 'lengthadjust', 'letter-spacing', 'kernelmatrix', 'kernelunitlength', 'lighting-color', 'local', 'marker-end', 'marker-mid', 'marker-start', 'markerheight', 'markerunits', 'markerwidth', 'maskcontentunits', 'maskunits', 'max', 'mask', 'media', 'method', 'mode', 'min', 'name', 'numoctaves', 'offset', 'operator', 'opacity', 'order', 'orient', 'orientation', 'origin', 'overflow', 'paint-order', 'path', 'pathlength', 'patterncontentunits', 'patterntransform', 'patternunits', 'points', 'preservealpha', 'preserveaspectratio', 'primitiveunits', 'r', 'rx', 'ry', 'radius', 'refx', 'refy', 'repeatcount', 'repeatdur', 'restart', 'result', 'rotate', 'scale', 'seed', 'shape-rendering', 'slope', 'specularconstant', 'specularexponent', 'spreadmethod', 'startoffset', 'stddeviation', 'stitchtiles', 'stop-color', 'stop-opacity', 'stroke-dasharray', 'stroke-dashoffset', 'stroke-linecap', 'stroke-linejoin', 'stroke-miterlimit', 'stroke-opacity', 'stroke', 'stroke-width', 'style', 'surfacescale', 'systemlanguage', 'tabindex', 'tablevalues', 'targetx', 'targety', 'transform', 'transform-origin', 'text-anchor', 'text-decoration', 'text-rendering', 'textlength', 'type', 'u1', 'u2', 'unicode', 'values', 'viewbox', 'visibility', 'version', 'vert-adv-y', 'vert-origin-x', 'vert-origin-y', 'width', 'word-spacing', 'wrap', 'writing-mode', 'xchannelselector', 'ychannelselector', 'x', 'x1', 'x2', 'xmlns', 'y', 'y1', 'y2', 'z', 'zoomandpan']);
    const mathMl = freeze(['accent', 'accentunder', 'align', 'bevelled', 'close', 'columnsalign', 'columnlines', 'columnspan', 'denomalign', 'depth', 'dir', 'display', 'displaystyle', 'encoding', 'fence', 'frame', 'height', 'href', 'id', 'largeop', 'length', 'linethickness', 'lspace', 'lquote', 'mathbackground', 'mathcolor', 'mathsize', 'mathvariant', 'maxsize', 'minsize', 'movablelimits', 'notation', 'numalign', 'open', 'rowalign', 'rowlines', 'rowspacing', 'rowspan', 'rspace', 'rquote', 'scriptlevel', 'scriptminsize', 'scriptsizemultiplier', 'selection', 'separator', 'separators', 'stretchy', 'subscriptshift', 'supscriptshift', 'symmetric', 'voffset', 'width', 'xmlns']);
    const xml = freeze(['xlink:href', 'xml:id', 'xlink:title', 'xml:space', 'xmlns:xlink']);
@@ -11045,7 +11052,7 @@
    function createDOMPurify() {
      let window = arguments.length > 0 && arguments[0] !== undefined ? arguments[0] : getGlobal();
      const DOMPurify = root => createDOMPurify(root);
-     DOMPurify.version = '3.2.6';
+     DOMPurify.version = '3.2.7';
      DOMPurify.removed = [];
      if (!window || !window.document || window.document.nodeType !== NODE_TYPE.document || !window.Element) {
        // Not running in a browser, provide a factory function
@@ -11742,7 +11749,7 @@
          // First condition does a very basic check if a) it's basically a valid custom element tagname AND
          // b) if the tagName passes whatever the user has configured for CUSTOM_ELEMENT_HANDLING.tagNameCheck
          // and c) if the attribute name passes whatever the user has configured for CUSTOM_ELEMENT_HANDLING.attributeNameCheck
-         _isBasicCustomElement(lcTag) && (CUSTOM_ELEMENT_HANDLING.tagNameCheck instanceof RegExp && regExpTest(CUSTOM_ELEMENT_HANDLING.tagNameCheck, lcTag) || CUSTOM_ELEMENT_HANDLING.tagNameCheck instanceof Function && CUSTOM_ELEMENT_HANDLING.tagNameCheck(lcTag)) && (CUSTOM_ELEMENT_HANDLING.attributeNameCheck instanceof RegExp && regExpTest(CUSTOM_ELEMENT_HANDLING.attributeNameCheck, lcName) || CUSTOM_ELEMENT_HANDLING.attributeNameCheck instanceof Function && CUSTOM_ELEMENT_HANDLING.attributeNameCheck(lcName)) ||
+         _isBasicCustomElement(lcTag) && (CUSTOM_ELEMENT_HANDLING.tagNameCheck instanceof RegExp && regExpTest(CUSTOM_ELEMENT_HANDLING.tagNameCheck, lcTag) || CUSTOM_ELEMENT_HANDLING.tagNameCheck instanceof Function && CUSTOM_ELEMENT_HANDLING.tagNameCheck(lcTag)) && (CUSTOM_ELEMENT_HANDLING.attributeNameCheck instanceof RegExp && regExpTest(CUSTOM_ELEMENT_HANDLING.attributeNameCheck, lcName) || CUSTOM_ELEMENT_HANDLING.attributeNameCheck instanceof Function && CUSTOM_ELEMENT_HANDLING.attributeNameCheck(lcName, lcTag)) ||
          // Alternative, second condition checks if it's an `is`-attribute, AND
          // the value passes whatever the user has configured for CUSTOM_ELEMENT_HANDLING.tagNameCheck
          lcName === 'is' && CUSTOM_ELEMENT_HANDLING.allowCustomizedBuiltInElements && (CUSTOM_ELEMENT_HANDLING.tagNameCheck instanceof RegExp && regExpTest(CUSTOM_ELEMENT_HANDLING.tagNameCheck, value) || CUSTOM_ELEMENT_HANDLING.tagNameCheck instanceof Function && CUSTOM_ELEMENT_HANDLING.tagNameCheck(value))) ; else {
@@ -11821,7 +11828,12 @@
            value = SANITIZE_NAMED_PROPS_PREFIX + value;
          }
          /* Work around a security issue with comments inside attributes */
-         if (SAFE_FOR_XML && regExpTest(/((--!?|])>)|<\/(style|title)/i, value)) {
+         if (SAFE_FOR_XML && regExpTest(/((--!?|])>)|<\/(style|title|textarea)/i, value)) {
+           _removeAttribute(name, currentNode);
+           continue;
+         }
+         /* Make sure we cannot easily use animated hrefs, even if animations are allowed */
+         if (lcName === 'attributename' && stringMatch(value, 'href')) {
            _removeAttribute(name, currentNode);
            continue;
          }
@@ -17511,22 +17523,22 @@
            const createKeyValueRow = (key, value) => {
                const row = document.createElement('div');
                row.className = 'igv-track-label-popover__row';
-               
+
                const keySpan = document.createElement('span');
                keySpan.className = 'igv-track-label-popover__key';
                keySpan.textContent = key + ':';
-               
+
                const valueSpan = document.createElement('span');
                valueSpan.className = 'igv-track-label-popover__value';
                valueSpan.textContent = value;
-               
+
                row.appendChild(keySpan);
                row.appendChild(valueSpan);
-               return row;
+               return row
            };
 
            const fragment = document.createDocumentFragment();
-           
+
            if (this.url) {
                if (isFile(this.url)) {
                    fragment.appendChild(createKeyValueRow('Filename', this.url.name));
@@ -17539,9 +17551,9 @@
                nameDiv.className = 'igv-track-label-popover__row';
                nameDiv.textContent = this.name;
                fragment.appendChild(nameDiv);
-               return fragment;
+               return fragment
            }
-           
+
            if (this.config) {
                if (this.config.metadata) {
                    for (let key of Object.keys(this.config.metadata)) {
@@ -17552,7 +17564,7 @@
 
                // Add any config properties that are capitalized
                for (let key of Object.keys(this.config)) {
-                   if (key.startsWith("_")) continue;   // transient property
+                   if (key.startsWith("_")) continue   // transient property
                    let first = key.substr(0, 1);
                    if (first !== first.toLowerCase()) {
                        const value = this.config[key];
@@ -17562,8 +17574,8 @@
                    }
                }
            }
-           
-           return fragment;
+
+           return fragment
        }
 
        /**
@@ -27005,14 +27017,14 @@
            if (phase) {
                stringA = sequenceInterval.getSequence(phaseExtentStart, phaseExtentEnd);
 
-               if (undefined === stringA) {
+               if (!stringA) {
                    return undefined
                }
 
                [ss, ee] = [getEonStart(riteExon), getEonStart(riteExon) + (3 - phase)];
                stringB = sequenceInterval.getSequence(ss, ee);
 
-               if (undefined === stringB) {
+               if (!stringB) {
                    return undefined
                }
 
@@ -27024,7 +27036,7 @@
            if (remainder) {
                stringB = sequenceInterval.getSequence(remainder.start, remainder.end);
 
-               if (undefined === stringB) {
+               if (!stringB) {
                    return undefined
                }
 
@@ -27032,7 +27044,7 @@
                const leftEnd = getExonEnd(leftExon);
                stringA = sequenceInterval.getSequence(leftEnd - leftPhase, leftEnd);
 
-               if (undefined === stringA) {
+               if (!stringA) {
                    return undefined
                }
 
@@ -27717,11 +27729,6 @@
     */
    function monitorTrackDrag(track) {
 
-       if (track.browser.on) {
-           track.browser.on('trackdragend', onDragEnd);
-           track.browser.on('trackremoved', unSubscribe);
-       }
-
        function onDragEnd() {
            if (track.trackView && track.displayMode !== "SQUISHED") {
                // Repaint views to adjust feature name if center is moved out of view
@@ -27729,13 +27736,11 @@
            }
        }
 
-       function unSubscribe(removedTrack) {
-           if (track.browser.un && track === removedTrack) {
-               track.browser.un('trackdragend', onDragEnd);
-               track.browser.un('trackremoved', unSubscribe);
-           }
+       if (track.browser.on) {
+           track.browser.on('trackdragend', onDragEnd);
        }
 
+
    }
 
    class RegionTableBase {
@@ -31586,6 +31591,8 @@
 
            this.overlayElement.style.top = `-${contentTop}px`;
 
+           if(!this.checkZoomIn()) return;
+
            if (!this.canvas) {
                this.repaint();
            } else {
@@ -32125,6 +32132,7 @@
                }
 
                event.preventDefault();
+               event.stopPropagation();
 
                // Track specific items
                let menuItems = [];
@@ -34758,7 +34766,7 @@
 
        }
 
-       presentMenuList(trackView, menuList) {
+       presentMenuList(trackView, menuList, config) {
 
            hideAllMenuPopups(this.parent);
 
@@ -34792,7 +34800,11 @@
 
                const { width } = this.popover.getBoundingClientRect();
 
-               this.popover.style.left = `${-width}px`;
+               if('left' === config.gearColumnPosition) {
+                   this.popover.style.right = `${width}px`;
+               } else {
+                   this.popover.style.left = `${-width}px`;
+               }
                this.popover.style.top = `${0}px`;
 
            }
@@ -35885,10 +35897,14 @@
 
        createAxis(browser, track) {
 
+           const axisColumn = browser.columnContainer.querySelector('.igv-axis-column');
+           if(!axisColumn) {
+               return;   // The axis column is optional.
+           }
+
            const axis = div();
            this.axis = axis;
-
-           browser.columnContainer.querySelector('.igv-axis-column').appendChild(axis);
+           axisColumn.appendChild(axis);
 
            axis.dataset.tracktype = track.type;
 
@@ -36067,6 +36083,7 @@
            this.dragHandle.style.height = `${newHeight}px`;
            this.gearContainer.style.height = `${newHeight}px`;
 
+           this.browser.fireEvent("trackheightchange", this);
        }
 
        updateScrollbar() {
@@ -36195,7 +36212,7 @@
 
            if (!(this.browser && this.browser.referenceFrameList)) return
 
-           const visibleViewports = this.viewports.filter(viewport => viewport.isVisible());
+           const visibleViewports = this.viewports.filter(viewport => viewport.isVisible() && viewport.checkZoomIn());
 
            // Shift viewports left/right to current genomic state (pans canvas)
            visibleViewports.forEach(viewport => viewport.shift());
@@ -36206,10 +36223,10 @@
            }
 
            // Filter zoomed out views.  This has the side effect or turning off or no the zoomed out notice
-           const viewportsToRepaint = visibleViewports.filter(vp => vp.needsRepaint()).filter(viewport => viewport.checkZoomIn());
+           const viewportsToRepaint = visibleViewports.filter(vp => vp.needsRepaint());
 
            // Get viewports that require a data load
-           const viewportsToReload = visibleViewports.filter(viewport => viewport.checkZoomIn()).filter(viewport => viewport.needsReload());
+           const viewportsToReload = visibleViewports.filter(viewport => viewport => viewport.needsReload());
 
            // Trigger viewport to load features needed to cover current genomic range
            // NOTE: these must be loaded synchronously, do not user Promise.all,  not all file readers are thread safe
@@ -36436,7 +36453,11 @@
 
                this.gear = div();
                this.gearContainer.appendChild(this.gear);
-               this.gear.appendChild(createIcon('cog'));
+               const cog = createIcon('cog');
+               if(false === browser.config.showGearColumn) {
+                   cog.style.color = 'white';
+               }
+               this.gear.appendChild(cog);
 
                this.trackGearPopup = new MenuPopup(this.gear);
 
@@ -36453,7 +36474,7 @@
                            otherTrackView.trackGearPopup.popover.style.display = 'none';
                        }
 
-                       this.trackGearPopup.presentMenuList(this, browser.menuUtils.trackMenuItemList(this));
+                       this.trackGearPopup.presentMenuList(this, browser.menuUtils.trackMenuItemList(this), browser.config);
                    } else {
                        this.trackGearPopup.popover.style.display = 'none';
                    }
@@ -37051,6 +37072,7 @@
                let value = this.browser.inputDialog.value;
                value = ('' === value || undefined === value) ? 'untitled' : value.trim();
                this.name = value;
+               this.browser.fireEvent('tracknamechange', [this]);
            };
 
            const config =
@@ -37139,6 +37161,184 @@
        return 1 === unique.length
    }
 
+   class InputDialog {
+
+       constructor(parent) {
+
+           this.parent = parent;
+
+           // dialog container
+           this.container = div({class: 'igv-ui-generic-dialog-container'});
+           parent.appendChild(this.container);
+
+           // dialog header
+           const header = div({class: 'igv-ui-generic-dialog-header'});
+           this.container.appendChild(header);
+
+           // dialog label
+           this.label = div({class: 'igv-ui-generic-dialog-one-liner'});
+           this.container.appendChild(this.label);
+           this.label.textContent = 'Unlabeled';
+
+           // input container
+           this.input_container = div({class: 'igv-ui-generic-dialog-input'});
+           this.container.appendChild(this.input_container);
+
+           // input element.  DO NOT ACCESS THIS OUTSIDE OF THIS CLASS
+           this._input = document.createElement("input");
+
+           if (InputDialog.FORM_EMBED_MODE) {
+               InputDialog.captureKeyInput(this._input);
+           }
+
+           this.input_container.appendChild(this._input);
+
+
+           // ok | cancel
+           const buttons = div({class: 'igv-ui-generic-dialog-ok-cancel'});
+           this.container.appendChild(buttons);
+
+           // ok
+
+           this.ok = div();
+           buttons.appendChild(this.ok);
+           this.ok.textContent = 'OK';
+
+           // cancel
+           this.cancel = div();
+           buttons.appendChild(this.cancel);
+           this.cancel.textContent = 'Cancel';
+
+           hide(this.container);
+
+           this._input.addEventListener('keyup', e => {
+               if ('Enter' === e.code) {
+                   if (typeof this.callback === 'function') {
+                       this.callback(this._input.value);
+                       this.callback = undefined;
+                   }
+                   this._input.value = undefined;
+                   hide(this.container);
+               }
+               e.stopImmediatePropagation();   // Prevent key event to cause track keyboard navigation ("next feature")
+           });
+
+           this.ok.addEventListener('click', () => {
+               if (typeof this.callback === 'function') {
+                   this.callback(this._input.value);
+                   this.callback = undefined;
+               }
+               this._input.value = undefined;
+               hide(this.container);
+           });
+
+           const cancel = () => {
+               this._input.value = '';
+               hide(this.container);
+           };
+
+           this.cancel.addEventListener('click', cancel);
+
+           attachDialogCloseHandlerWithParent(header, cancel);
+           makeDraggable(this.container, header);
+
+       }
+
+       get value() {
+           return purify.sanitize(this._input.value)
+       }
+
+
+       present(options, e) {
+           this.label.textContent = options.label;
+           this._input.value = options.value;
+           this.callback = options.callback || options.click;
+
+           this.container.style.display = '';
+
+           const {clientX, clientY} = e;
+           const {offsetWidth: dialogWidth, offsetHeight: dialogHeight} = this.container;
+           const {innerHeight: windowHeight} = window;
+           const windowWidth = document.documentElement.clientWidth;
+
+           const padding = 10;
+
+           // Calculate initial centered position
+           let left = clientX - (dialogWidth / 2);
+           let top = clientY - (dialogHeight / 2);
+
+           // Clamp horizontal position to viewport
+           const minLeft = padding;
+           const maxLeft = windowWidth - dialogWidth - padding;
+           left = Math.max(minLeft, Math.min(left, maxLeft));
+
+           // Clamp vertical position to viewport
+           const minTop = padding;
+           const maxTop = windowHeight - dialogHeight - padding;
+           top = Math.max(minTop, Math.min(top, maxTop));
+
+           this.container.style.left = `${left}px`;
+           this.container.style.top = `${top}px`;
+       }
+
+       /**
+        * Capture key input in embedded form mode to prevent parent form handling.  This is a workaround for pages
+        * that embed igv.js in a form element which has key listeners.  Without this the parent form will handle key events,
+        * even if stopPropagation() is called.
+        *
+        * @param input
+        */
+       static captureKeyInput(input) {
+
+           input.addEventListener('mousedown', (e) => {
+               input.focus(); // Explicitly set focus on the input element
+           });
+
+           // Prevent key event propagation to parent form
+           input.addEventListener('keydown', e => {
+
+               // Prevent parent listeners from handling this event.
+               e.preventDefault();
+               e.stopPropagation();
+
+               const start = input.selectionStart;
+               const end = input.selectionEnd;
+
+               if (e.key.length === 1) {
+                   // Handle printable characters
+                   const value = input.value;
+                   input.value = value.slice(0, start) + e.key + value.slice(end);
+                   input.selectionStart = input.selectionEnd = start + 1;
+               } else if (e.key === 'Backspace') {
+                   if (start === end && start > 0) {
+                       // No selection, delete character before cursor
+                       input.value = input.value.slice(0, start - 1) + input.value.slice(start);
+                       input.selectionStart = input.selectionEnd = start - 1;
+                   } else if (start < end) {
+                       // Delete selection
+                       input.value = input.value.slice(0, start) + input.value.slice(end);
+                       input.selectionStart = input.selectionEnd = start;
+                   }
+               } else if (e.key === 'Delete') {
+                   if (start === end && start < input.value.length) {
+                       // No selection, delete character after cursor
+                       input.value = input.value.slice(0, start) + input.value.slice(start + 1);
+                       input.selectionStart = input.selectionEnd = start;
+                   } else if (start < end) {
+                       // Delete selection
+                       input.value = input.value.slice(0, start) + input.value.slice(end);
+                       input.selectionStart = input.selectionEnd = start;
+                   }
+               } else if (e.key === 'ArrowLeft') {
+                   input.selectionStart = input.selectionEnd = Math.max(0, start - 1);
+               } else if (e.key === 'ArrowRight') {
+                   input.selectionStart = input.selectionEnd = Math.min(input.value.length, start + 1);
+               }
+
+           }, true); // Use the capturing phase.
+       }
+   }
+
    class DataRangeDialog {
 
        constructor(browser, parent) {
@@ -37170,6 +37370,9 @@
            this.minimum.appendChild(minDiv);
 
            this.minimumInput = document.createElement('input');
+           if (InputDialog.FORM_EMBED_MODE) {
+               InputDialog.captureKeyInput(this.minimumInput);
+           }
            this.minimum.appendChild(this.minimumInput);
 
            // Create maximum input
@@ -37182,6 +37385,9 @@
            this.maximum.appendChild(maxDiv);
 
            this.maximumInput = document.createElement('input');
+           if (InputDialog.FORM_EMBED_MODE) {
+               InputDialog.captureKeyInput(this.maximumInput);
+           }
            this.maximum.appendChild(this.maximumInput);
 
            // Create buttons container
@@ -37218,7 +37424,7 @@
 
            // Determine the data range
            if (Array.isArray(trackViewOrTrackViewList)) {
-               dataRange = { min: Number.MAX_SAFE_INTEGER, max: -Number.MAX_SAFE_INTEGER };
+               dataRange = {min: Number.MAX_SAFE_INTEGER, max: -Number.MAX_SAFE_INTEGER};
                for (const trackView of trackViewOrTrackViewList) {
                    if (trackView.track.dataRange) {
                        dataRange.min = Math.min(trackView.track.dataRange.min, dataRange.min);
@@ -37244,7 +37450,7 @@
            };
 
            this.maximumInput.onkeyup = null;
-           this.maximumInput.onkeyup = e=> {
+           this.maximumInput.onkeyup = e => {
                if (e.keyCode === 13) { // Enter key
                    e.stopImmediatePropagation();
                    this.processResults(trackViewOrTrackViewList);
@@ -37273,7 +37479,7 @@
                        : [trackViewOrTrackViewList];
 
                    for (const trackView of list) {
-                       trackView.track.setDataRange({ min, max });
+                       trackView.track.setDataRange({min, max});
                    }
                }
 
@@ -37285,140 +37491,38 @@
            this.hide();
        }
 
-       hide(){
+       hide() {
            this.container.style.top = '20%';
            this.container.style.left = '75%';
            this.container.style.display = 'none';
        }
 
        present(e) {
-           const { top} = e.currentTarget.parentElement.getBoundingClientRect();
-           this.container.style.top = `${ top }px`;
-           this.container.style.display = 'flex';
-       }
-
-   }
-
-   class InputDialog {
-
-       constructor(parent) {
-
-           this.parent = parent;
-
-           // dialog container
-           this.container = div({class: 'igv-ui-generic-dialog-container'});
-           parent.appendChild(this.container);
-
-           // dialog header
-           const header = div({class: 'igv-ui-generic-dialog-header'});
-           this.container.appendChild(header);
-
-           // dialog label
-           this.label = div({class: 'igv-ui-generic-dialog-one-liner'});
-           this.container.appendChild(this.label);
-           this.label.textContent = 'Unlabeled';
-
-           // input container
-           this.input_container = div({class: 'igv-ui-generic-dialog-input'});
-           this.container.appendChild(this.input_container);
-
-           // input element.  DO NOT ACCESS THIS OUTSIDE OF THIS CLASS
-           this._input = document.createElement("input");
-           this.input_container.appendChild(this._input);
-
-
-           // ok | cancel
-           const buttons = div({class: 'igv-ui-generic-dialog-ok-cancel'});
-           this.container.appendChild(buttons);
-
-           // ok
-           this.ok = div();
-           buttons.appendChild(this.ok);
-           this.ok.textContent = 'OK';
-
-           // cancel
-           this.cancel = div();
-           buttons.appendChild(this.cancel);
-           this.cancel.textContent = 'Cancel';
-
-           hide(this.container);
-
-           this._input.addEventListener('keyup', e => {
-               if ('Enter' === e.code) {
-                   if (typeof this.callback === 'function') {
-                       this.callback(this._input.value);
-                       this.callback = undefined;
-                   }
-                   this._input.value = undefined;
-                   hide(this.container);
-               }
-               e.stopImmediatePropagation();   // Prevent key event to cause track keyboard navigation ("next feature")
-           });
-
-           this.ok.addEventListener('click', () => {
-               if (typeof this.callback === 'function') {
-                   this.callback(this._input.value);
-                   this.callback = undefined;
-               }
-               this._input.value = undefined;
-               hide(this.container);
-           });
-
-           const cancel = () => {
-               this._input.value = '';
-               hide(this.container);
-           };
 
-           this.cancel.addEventListener('click', cancel);
+           // Make the dialog visible to measure its dimensions
+           this.container.style.display = 'flex';
 
-           attachDialogCloseHandlerWithParent(header, cancel);
-           makeDraggable(this.container, header);
+           const {clientX, clientY} = e;
+           const {offsetWidth: dialogWidth, offsetHeight: dialogHeight} = this.container;
+           const {innerHeight: windowHeight} = window;
+           const windowWidth = document.documentElement.clientWidth;
 
-       }
+           const padding = 10;
 
-       get value() {
-           return purify.sanitize(this._input.value)
-       }
+           // Calculate initial centered position
+           let left = clientX - (dialogWidth / 2);
+           let top = clientY - (dialogHeight / 2);
 
+           // Clamp horizontal position to viewport
+           const minLeft = padding;
+           const maxLeft = windowWidth - dialogWidth - padding;
+           left = Math.max(minLeft, Math.min(left, maxLeft));
 
-       present(options, e) {
-           this.label.textContent = options.label;
-           this._input.value = options.value;
-           this.callback = options.callback || options.click;
+           // Clamp vertical position to viewport
+           const minTop = padding;
+           const maxTop = windowHeight - dialogHeight - padding;
+           top = Math.max(minTop, Math.min(top, maxTop));
 
-           this.container.style.display = '';
-           
-           // Get click coordinates
-           const clickX = e.clientX;
-           const clickY = e.clientY;
-           
-           // Get dialog dimensions
-           const dialogWidth = this.container.offsetWidth;
-           const dialogHeight = this.container.offsetHeight;
-           
-           // Calculate available space
-           const windowWidth = window.innerWidth;
-           const windowHeight = window.innerHeight;
-           
-           // Calculate position to keep dialog on screen
-           let left = clickX;
-           let top = clickY;
-           
-           // Adjust horizontal position if dialog would go off screen
-           if (left + dialogWidth > windowWidth) {
-               left = windowWidth - dialogWidth - 10; // 10px padding from edge
-           }
-           
-           // Adjust vertical position if dialog would go off screen
-           if (top + dialogHeight > windowHeight) {
-               top = windowHeight - dialogHeight - 10; // 10px padding from edge
-           }
-           
-           // Ensure minimum distance from edges
-           left = Math.max(10, left);
-           top = Math.max(10, top);
-           
-           // Apply positions
            this.container.style.left = `${left}px`;
            this.container.style.top = `${top}px`;
        }
@@ -37561,7 +37665,7 @@
 
        }
 
-       updateRecentColorsSwatches(colorHandler){
+       updateRecentColorsSwatches(colorHandler) {
            this.recentColorsSwatches.innerHTML = '';
            for (const hexColorString of this.recentColors) {
                const swatch = div({class: 'igv-ui-color-swatch'});
@@ -37581,7 +37685,7 @@
            colorPickerContainer.style.position = 'absolute';
            moreColorsContainer.appendChild(colorPickerContainer);
 
-           const { width, height } = moreColorsContainer.getBoundingClientRect();
+           const {width, height} = moreColorsContainer.getBoundingClientRect();
            colorPickerContainer.style.right = `${0}px`;
            colorPickerContainer.style.top = `${0}px`;
            colorPickerContainer.style.width = `${width}px`;
@@ -37616,7 +37720,7 @@
            picker.onDone = color => {
 
                // Remove alpha from hex color string
-               const hexColorString = color.hex.substring(0,7);
+               const hexColorString = color.hex.substring(0, 7);
 
                this.recentColors.unshift(hexColorString);
 
@@ -37636,10 +37740,34 @@
            picker.show();
        }
 
-       present(event){
-           const { top} = event.currentTarget.parentElement.getBoundingClientRect();
-           this.container.style.top = `${ top }px`;
+       present(event) {
+
+           // Make the dialog visible to measure its dimensions
            this.show();
+
+           const {clientX, clientY} = event;
+           const {offsetWidth: containerWidth, offsetHeight: containerHeight} = this.container;
+           const {innerHeight: windowHeight} = window;
+           const windowWidth = document.documentElement.clientWidth;
+
+           const padding = 10;
+
+           // Calculate initial centered position
+           let left = clientX - (containerWidth / 2);
+           let top = clientY;
+
+           // Clamp horizontal position to viewport
+           const minLeft = padding;
+           const maxLeft = windowWidth - containerWidth - padding;
+           left = Math.max(minLeft, Math.min(left, maxLeft));
+
+           // Clamp vertical position to viewport
+           const minTop = padding;
+           const maxTop = windowHeight - containerHeight - padding;
+           top = Math.max(minTop, Math.min(top, maxTop));
+
+           this.container.style.left = `${left}px`;
+           this.container.style.top = `${top}px`;
        }
 
    }
@@ -38845,6 +38973,7 @@
        ["N", "Unknown"]
    ]);
 
+   const EMPTY_SET$1 = new Set();
 
    function modificationName(modification) {
        return  (codeValues.has(modification)) ? codeValues.get(modification) : "Uknown"
@@ -38863,6 +38992,11 @@
     * @return List<BaseModificationSet>
     */
    function getBaseModificationSets(mm, ml, sequence, isNegativeStrand) {
+
+       if(!sequence) {
+           return EMPTY_SET$1
+       }
+
        if (isNegativeStrand) {
            sequence = reverseComplementSequence(sequence);
        }
@@ -41904,7 +42038,7 @@
    }
 
    /*! For license information please see cram-bundle.js.LICENSE.txt */
-   var gmodCRAM = (()=>{var e={4923:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0});const n=r(9747),i=r(5931),a=r(8876);function A(e,t){const[r,n,i,a,A,s]=t,o=r;e[o]||(e[o]=[]),e[o].push({start:n,span:i,containerStart:a,sliceStart:A,sliceBytes:s});}t.default=class{constructor(e){this.filehandle=(0, i.open)(e.url,e.path,e.filehandle);}async parseIndex(){const e={},t=31===(r=await this.filehandle.readFile())[0]&&139===r[1]?(0, a.unzip)(r):r;var r;const i=new DataView(t.buffer);if(t.length>4&&21578050===i.getUint32(0,!0))throw new n.CramMalformedError("invalid .crai index file. note: file appears to be a .bai index. this is technically legal but please open a github issue if you need support");let s=[],o="";for(const r of t)if(r>=48&&r<=57||!o&&45===r)o+=String.fromCharCode(r);else if(9===r)s.push(Number.parseInt(o,10)),o="";else if(10===r)s.push(Number.parseInt(o,10)),o="",A(e,s),s=[];else if(13!==r&&32!==r)throw new n.CramMalformedError("invalid .crai index file");return o&&s.push(Number.parseInt(o,10)),6===s.length&&A(e,s),Object.entries(e).forEach((([t,r])=>{const n=r;e[t]=n.sort(((e,t)=>e.start-t.start||e.span-t.span));})),e}getIndex(){return this.parseIndexP||(this.parseIndexP=this.parseIndex().catch((e=>{throw this.parseIndexP=void 0,e}))),this.parseIndexP}async hasDataForReferenceSequence(e){return !!(await this.getIndex())[e]}async getEntriesForRange(e,t,r){const n=(await this.getIndex())[e];if(!n)return [];const i=e=>{const n=e.start,i=e.start+e.span;return n>r?-1:i<=t?1:0},a=[];for(const e of n)0===i(e)&&a.push(e);return a}};},9508:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(e,t){this.parameters=e,this.dataType=t;}};},368:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(9508)),a=r(612),A=r(9747);class s extends i.default{constructor(e,t){if(super(e,t),"int"!==this.dataType)throw new A.CramUnimplementedError(`${this.dataType} decoding not yet implemented by BETA codec`)}decode(e,t,r,n){return (0, a.getBits)(t.content,n.coreBlock,this.parameters.length)-this.parameters.offset}}t.default=s;},8635:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(9508)),a=r(400);class A extends i.default{constructor(e,t,r){super(e,t),this.instantiateCodec=r;}decode(e,t,r,n){const i=this._getLengthCodec().decode(e,t,r,n)||0,a=this._getDataCodec(),A=new Uint8Array(i);for(let s=0;s<i;s+=1)A[s]=a.decode(e,t,r,n)||0;return A}_getLengthCodec(){const e=this.parameters.lengthsEncoding;return this.instantiateCodec(e,"int")}_getDataCodec(){const e=this.parameters.valuesEncoding;return this.instantiateCodec(e,"byte")}}t.default=A,"_getLengthCodec _getDataCodec".split(" ").forEach((e=>{(0, a.tinyMemoize)(A,e);}));},4839:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(9508)),a=r(9747),A=r(612);class s extends i.default{decode(e,t,r,n){const{blockContentId:i}=this.parameters,A=r[i];if(!A)throw new a.CramMalformedError(`no block found with content ID ${i}`);const s=n.externalBlocks.getCursor(i);return this._decodeByteArray(A,s)}_decodeByteArray(e,t){const r=e.content,{stopByte:n}=this.parameters,i=t.bytePosition;let a=t.bytePosition;for(;r[a]!==n&&a<r.length;){if(a===r.length)throw new A.CramBufferOverrunError("byteArrayStop reading beyond length of data buffer?");a+=1;}return t.bytePosition=a+1,r.subarray(i,a)}}t.default=s;},8153:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(9508)),a=r(9747),A=r(400),s=r(612);class o extends i.default{constructor(e,t){if(super(e,t),"int"===this.dataType)this._decodeData=this._decodeInt;else {if("byte"!==this.dataType)throw new a.CramUnimplementedError(`${this.dataType} decoding not yet implemented by EXTERNAL codec`);this._decodeData=this._decodeByte;}}decode(e,t,r,n){const{blockContentId:i}=this.parameters,a=r[i],A=n.externalBlocks.getCursor(i);return a?this._decodeData(a,A):void 0}_decodeInt(e,t){const[r,n]=(0, A.parseItf8)(e.content,t.bytePosition);return t.bytePosition=t.bytePosition+n,r}_decodeByte(e,t){if(t.bytePosition>=e.content.length)throw new s.CramBufferOverrunError("attempted to read beyond end of block. this file seems truncated.");return e.content[t.bytePosition++]}}t.default=o;},8185:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(9508)),a=r(612),A=r(9747);class s extends i.default{constructor(e,t){if(super(e,t),"int"!==this.dataType)throw new A.CramUnimplementedError(`${this.dataType} decoding not yet implemented by GAMMA codec`)}decode(e,t,r,n){let i=1;for(;0===(0, a.getBits)(t.content,n.coreBlock,1);)i+=1;return ((0, a.getBits)(t.content,n.coreBlock,i-1)|1<<i-1)-this.parameters.offset}}t.default=s;},612:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.CramBufferOverrunError=void 0,t.getBits=function(e,t,n){let i=0;if(t.bytePosition+(7-t.bitPosition+n)/8>e.length)throw new r("read error during decoding. the file seems to be truncated.");for(let r=n;r;r--)i<<=1,i|=e[t.bytePosition]>>t.bitPosition&1,t.bitPosition-=1,t.bitPosition<0&&(t.bytePosition+=1),t.bitPosition&=7;return i};class r extends Error{}t.CramBufferOverrunError=r;},4341:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(9508)),a=r(612),A=r(9747);class s extends i.default{constructor(e,t){if(super(e,t),this.codes={},this.codeBook={},this.sortedCodes=[],this.sortedValuesByBitCode=[],this.sortedBitCodes=[],this.sortedBitLengthsByBitCode=[],this.bitCodeToValue=[],!["byte","int"].includes(this.dataType))throw new TypeError(`${this.dataType} decoding not yet implemented by HUFFMAN_INT codec`);this.buildCodeBook(),this.buildCodes(),this.buildCaches(),0===this.sortedCodes[0].bitLength&&(this._decode=this._decodeZeroLengthCode);}buildCodeBook(){let e=new Array(this.parameters.numCodes);for(let t=0;t<this.parameters.numCodes;t++)e[t]={symbol:this.parameters.symbols[t],bitLength:this.parameters.bitLengths[t]};e=e.sort(((e,t)=>e.bitLength-t.bitLength||e.symbol-t.symbol)),this.codeBook={},e.forEach((e=>{this.codeBook[e.bitLength]||(this.codeBook[e.bitLength]=[]),this.codeBook[e.bitLength].push(e.symbol);}));}buildCodes(){this.codes={};let e=0,t=-1;Object.entries(this.codeBook).forEach((([r,n])=>{const i=Number.parseInt(r,10);n.forEach((r=>{const n={bitLength:i,value:r,bitCode:0};t+=1;const a=i-e;if(t<<=a,n.bitCode=t,e+=a,function(e){let t=e-(e>>1)&1431655765;return t=(858993459&t)+(t>>2&858993459),16843009*(t+(t>>4)&252645135)>>24}(t)>i)throw new A.CramMalformedError("Symbol out of range");this.codes[r]=n;}));}));}buildCaches(){this.sortedCodes=Object.values(this.codes).sort(((e,t)=>e.bitLength-t.bitLength||e.bitCode-t.bitCode)),this.sortedValuesByBitCode=this.sortedCodes.map((e=>e.value)),this.sortedBitCodes=this.sortedCodes.map((e=>e.bitCode)),this.sortedBitLengthsByBitCode=this.sortedCodes.map((e=>e.bitLength));const e=Math.max(...this.sortedBitCodes);this.bitCodeToValue=new Array(e+1).fill(-1);for(let e=0;e<this.sortedBitCodes.length;e+=1)this.bitCodeToValue[this.sortedCodes[e].bitCode]=e;}decode(e,t,r,n){return this._decode(e,t,n.coreBlock)}_decodeZeroLengthCode(){return this.sortedCodes[0].value}_decode(e,t,r){const n=t.content;let i=0,s=0;for(let e=0;e<this.sortedCodes.length;e+=1){const t=this.sortedCodes[e].bitLength;s<<=t-i,s|=(0, a.getBits)(n,r,t-i),i=t;{const r=this.bitCodeToValue[s];if(r>-1&&this.sortedBitLengthsByBitCode[r]===t)return this.sortedValuesByBitCode[r];for(let r=e;this.sortedCodes[r+1].bitLength===t&&r<this.sortedCodes.length;r+=1)e+=1;}}throw new A.CramMalformedError("Huffman symbol not found.")}}t.default=s;},6524:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.instantiateCodec=function e(t,r){const n=(i="ignore"===r?0:t.codecId,f[i]);var i;if(!n)throw new l.CramUnimplementedError(`no codec implemented for codec ID ${t.codecId}`);return new n(t.parameters,r,e)};const i=n(r(368)),a=n(r(8635)),A=n(r(4839)),s=n(r(8153)),o=n(r(8185)),c=n(r(4341)),d=n(r(99)),l=r(9747),f={1:s.default,3:c.default,4:a.default,5:A.default,6:i.default,7:d.default,9:o.default};},99:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(9508)),a=r(612),A=r(9747);class s extends i.default{constructor(e,t){if(super(e,t),"int"!==this.dataType)throw new A.CramUnimplementedError(`${this.dataType} decoding not yet implemented by SUBEXP codec`)}decode(e,t,r,n){let i,A,s=0;for(;(0, a.getBits)(t.content,n.coreBlock,1);)s+=1;return 0===s?(i=this.parameters.K,A=(0, a.getBits)(t.content,n.coreBlock,i)):(i=s+this.parameters.K-1,A=1<<i|(0, a.getBits)(t.content,n.coreBlock,i)),A-this.parameters.offset}}t.default=s;},7295:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default={CRAM_FLAG_PRESERVE_QUAL_SCORES:1,CRAM_FLAG_DETACHED:2,CRAM_FLAG_MATE_DOWNSTREAM:4,CRAM_FLAG_NO_SEQ:8,CRAM_FLAG_MASK:15,CRAM_M_REVERSE:1,CRAM_M_UNMAP:2,BAM_FPAIRED:1,BAM_FPROPER_PAIR:2,BAM_FUNMAP:4,BAM_FMUNMAP:8,BAM_FREVERSE:16,BAM_FMREVERSE:32,BAM_FREAD1:64,BAM_FREAD2:128,BAM_FSECONDARY:256,BAM_FQCFAIL:512,BAM_FDUP:1024,BAM_FSUPPLEMENTARY:2048,BAM_CMATCH:0,BAM_CINS:1,BAM_CDEL:2,BAM_CREF_SKIP:3,BAM_CSOFT_CLIP:4,BAM_CHARD_CLIP:5,BAM_CPAD:6,BAM_CEQUAL:7,BAM_CDIFF:8,BAM_CBACK:9,BAM_CIGAR_STR:"MIDNSHP:XB",BAM_CIGAR_SHIFT:4,BAM_CIGAR_MASK:15,BAM_CIGAR_TYPE:246183};},7219:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0});const n=r(9747),i=r(6524),a={BF:"int",CF:"int",RI:"int",RL:"int",AP:"int",RG:"int",MF:"int",NS:"int",NP:"int",TS:"int",NF:"int",TC:"byte",TN:"int",FN:"int",FC:"byte",FP:"int",BS:"byte",IN:"byteArray",SC:"byteArray",DL:"int",BA:"byte",BB:"byteArray",RS:"int",PD:"int",HC:"int",MQ:"int",RN:"byteArray",QS:"byte",QQ:"byteArray",TL:"int"};t.default=class{constructor(e){this.dataSeriesCodecCache={},this.tagCodecCache={},this.tagEncoding={},this.readNamesIncluded=e.preservation.RN,this.APdelta=e.preservation.AP,this.referenceRequired=!!e.preservation.RR,this.tagIdsDictionary=e.preservation.TD,this.substitutionMatrix=function(e){const t=new Array(5);for(let e=0;e<5;e+=1)t[e]=new Array(4);return t[0][e[0]>>6&3]="C",t[0][e[0]>>4&3]="G",t[0][e[0]>>2&3]="T",t[0][3&e[0]]="N",t[1][e[1]>>6&3]="A",t[1][e[1]>>4&3]="G",t[1][e[1]>>2&3]="T",t[1][3&e[1]]="N",t[2][e[2]>>6&3]="A",t[2][e[2]>>4&3]="C",t[2][e[2]>>2&3]="T",t[2][3&e[2]]="N",t[3][e[3]>>6&3]="A",t[3][e[3]>>4&3]="C",t[3][e[3]>>2&3]="G",t[3][3&e[3]]="N",t[4][e[4]>>6&3]="A",t[4][e[4]>>4&3]="C",t[4][e[4]>>2&3]="G",t[4][3&e[4]]="T",t}(e.preservation.SM),this.dataSeriesEncoding=e.dataSeriesEncoding,this.tagEncoding=e.tagEncoding;}getCodecForTag(e){const t=this.tagCodecCache[e];if(t)return t;{const t=this.tagEncoding[e];if(!t)throw new Error("Error, no tag encoding");const r=(0, i.instantiateCodec)(t,"byteArray");return this.tagCodecCache[e]=r,r}}getTagNames(e){return this.tagIdsDictionary[e]}getCodecForDataSeries(e){let t=this.dataSeriesCodecCache[e];if(void 0===t){const r=this.dataSeriesEncoding[e];if(r){const A=a[e];if(!A)throw new n.CramMalformedError(`data series name ${e} not defined in file compression header`);t=(0, i.instantiateCodec)(r,A),this.dataSeriesCodecCache[e]=t;}}return t}toJSON(){const e={};return Object.keys(this).forEach((t=>{t.endsWith("Cache")||(e[t]=this[t]);})),e}};},78:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=r(9747),a=n(r(6771)),A=r(400),s=n(r(7219)),o=r(3165);class c{constructor(e,t){this.file=e,this.filePosition=t;}getHeader(){return this._readContainerHeader(this.filePosition)}async getCompressionHeaderBlock(){if(!(await this.getHeader()).numRecords)return null;const{majorVersion:e}=await this.file.getDefinition(),t=(0, o.getSectionParsers)(e),r=await this.getFirstBlock();if("COMPRESSION_HEADER"!==r.contentType)throw new i.CramMalformedError(`invalid content type ${r.contentType} in compression header block`);const n=(0, A.parseItem)(r.content,t.cramCompressionHeader.parser,0,r.contentPosition);return {...r,parsedContent:n}}async getFirstBlock(){const e=await this.getHeader();return this.file.readBlock(e._endPosition)}async getCompressionScheme(){const e=await this.getCompressionHeaderBlock();if(e)return new s.default(e.parsedContent)}getSlice(e,t){return new a.default(this,e,t)}async _readContainerHeader(e){const{majorVersion:t}=await this.file.getDefinition(),r=(0, o.getSectionParsers)(t),{cramContainerHeader1:n,cramContainerHeader2:i}=r,a=await this.file.read(n.maxLength,e),s=(0, A.parseItem)(a,n.parser),c=(0, A.itf8Size)(s.numLandmarks),d=await this.file.read(i.maxLength(s.numLandmarks),e+s._size-c),l=(0, A.parseItem)(d,i.parser);return this.file.validateChecksums&&void 0!==l.crc32&&await this.file.checkCrc32(e,s._size+l._size-c-4,l.crc32,`container header beginning at position ${e}`),{...s,...l,_size:s._size+l._size-c,_endPosition:s._size+l._size-c+e}}}t.default=c,"getHeader getCompressionHeaderBlock getCompressionScheme".split(" ").forEach((e=>{(0, A.tinyMemoize)(c,e);}));},6794:function(e,t,r){var n,i=this&&this.__createBinding||(Object.create?function(e,t,r,n){void 0===n&&(n=r);var i=Object.getOwnPropertyDescriptor(t,r);i&&!("get"in i?!t.__esModule:i.writable||i.configurable)||(i={enumerable:!0,get:function(){return t[r]}}),Object.defineProperty(e,n,i);}:function(e,t,r,n){void 0===n&&(n=r),e[n]=t[r];}),a=this&&this.__setModuleDefault||(Object.create?function(e,t){Object.defineProperty(e,"default",{enumerable:!0,value:t});}:function(e,t){e.default=t;}),A=this&&this.__importStar||(n=function(e){return n=Object.getOwnPropertyNames||function(e){var t=[];for(var r in e)Object.prototype.hasOwnProperty.call(e,r)&&(t[t.length]=r);return t},n(e)},function(e){if(e&&e.__esModule)return e;var t={};if(null!=e)for(var r=n(e),A=0;A<r.length;A++)"default"!==r[A]&&i(t,e,r[A]);return a(t,e),t}),s=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const o=s(r(86)),c=s(r(7392)),d=r(1307),l=r(9747),f=A(r(9151)),g=r(5931),h=s(r(9989)),u=r(5417),C=r(9995),I=r(8876),_=s(r(78)),m=r(3165),B=r(400);class p{constructor(e){if(this.file=(0, g.open)(e.url,e.path,e.filehandle),this.validateChecksums=!0,this.fetchReferenceSequenceCallback=e.seqFetch,this.options={checkSequenceMD5:e.checkSequenceMD5,cacheSize:e.cacheSize??2e4},this.featureCache=new c.default({maxSize:this.options.cacheSize}),function(){const e=new Uint32Array([287454020]),t=new Uint8Array(e.buffer);return 68===t[0]?0:17===t[0]?1:2}()>0)throw new Error("Detected big-endian machine, may be unable to run")}read(e,t){return this.file.read(e,t)}async getDefinition(){const{maxLength:e,parser:t}=(0, m.cramFileDefinition)(),r=t(await this.file.read(e,0)).value;if(2!==r.majorVersion&&3!==r.majorVersion)throw new l.CramUnimplementedError(`CRAM version ${r.majorVersion} not supported`);return r}async getSamHeader(){const e=await this.getContainerById(0);if(!e)throw new l.CramMalformedError("file contains no containers");const t=(await e.getFirstBlock()).content,r=new DataView(t.buffer).getInt32(0,!0),n=new TextDecoder("utf8").decode(t.subarray(4,4+r));return this.header=n,(0, u.parseHeaderText)(n)}async getHeaderText(){return await this.getSamHeader(),this.header}async getContainerById(e){const{majorVersion:t}=await this.getDefinition();let r,n=(0, m.getSectionParsers)(t).cramFileDefinition.maxLength;for(let t=0;t<=e;t++){r=this.getContainerAtPosition(n);const e=await r.getHeader();if(0===t){n=e._endPosition;for(let t=0;t<e.numBlocks;t++)n=(await this.readBlock(n))._endPosition;}else n+=e._size+e.length;}return r}async checkCrc32(e,t,r,n){const i=await this.file.read(t,e),a=(0, o.default)(i)>>>0;if(a!==r)throw new l.CramMalformedError(`crc mismatch in ${n}: recorded CRC32 = ${r}, but calculated CRC32 = ${a}`)}async containerCount(){const{majorVersion:e}=await this.getDefinition();let t=0,r=(0, m.getSectionParsers)(e).cramFileDefinition.maxLength;try{for(;;){const e=await this.getContainerAtPosition(r).getHeader();if(0===t){r=e._endPosition;for(let t=0;t<e.numBlocks;t++)r=(await this.readBlock(r))._endPosition;}else r+=e._size+e.length;t+=1;}}catch(e){t--;}return t}getContainerAtPosition(e){return new _.default(this,e)}async readBlockHeader(e){const{majorVersion:t}=await this.getDefinition(),r=(0, m.getSectionParsers)(t),{cramBlockHeader:n}=r,i=await this.file.read(n.maxLength,e);return (0, B.parseItem)(i,n.parser,0,e)}async _parseSection(e,t,r=e.maxLength,n){const i=n??await this.file.read(r,t),a=(0, B.parseItem)(i,e.parser,0,t);if(a._size!==r)throw new l.CramMalformedError(`section read error: requested size ${r} does not equal parsed size ${a._size}`);return a}async _uncompressPre(e,t,r){if("gzip"===e){const e=(0, I.unzip)(t);return e[0],e}if("bzip2"===e)return (0, C.decode)(t);if("lzma"===e){const e=new Response(new d.XzReadableStream((n=t,new ReadableStream({start(e){e.enqueue(n),e.close();}}))));return new Uint8Array(await e.arrayBuffer())}if("rans"===e){const e=new Uint8Array(r);return (0, h.default)(t,e),e}if("rans4x16"===e)return f.r4x16_uncompress(t);if("arith"===e)return f.arith_uncompress(t);if("fqzcomp"===e)return f.fqzcomp_uncompress(t);if("tok3"===e)return f.tok3_uncompress(t);throw new l.CramUnimplementedError(`${e} decompression not yet implemented`);var n;}async _uncompress(e,t,r){const n=await this._uncompressPre(e,t,r);if(n.length!==r){const e=new Uint8Array(r);return e.set(n,0),e}return n}async readBlock(e){const{majorVersion:t}=await this.getDefinition(),r=(0, m.getSectionParsers)(t),n=await this.readBlockHeader(e),i=n._endPosition,a=await this.file.read(n.compressedSize,i),A="raw"!==n.compressionMethod?await this._uncompress(n.compressionMethod,a,n.uncompressedSize):a,s={...n,_endPosition:i,contentPosition:i,content:A};if(t>=3){const t=await this._parseSection(r.cramBlockCrc32,i+n.compressedSize);s.crc32=t.crc32,this.validateChecksums&&await this.checkCrc32(e,n._size+n.compressedSize,t.crc32,"block data"),s._endPosition=t._endPosition,s._size=s.compressedSize+r.cramBlockCrc32.maxLength;}else s._endPosition=i+s.compressedSize,s._size=s.compressedSize;return s}}t.default=p,"getDefinition getSectionParsers getSamHeader".split(" ").forEach((e=>{(0, B.tinyMemoize)(p,e);}));},7390:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.default=t.CramRecord=void 0;var i=r(8401);Object.defineProperty(t,"CramRecord",{enumerable:!0,get:function(){return n(i).default}});var a=r(6794);Object.defineProperty(t,"default",{enumerable:!0,get:function(){return n(a).default}});},8401:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.MateFlagsDecoder=t.CramFlagsDecoder=t.BamFlagsDecoder=t.MateFlags=t.CramFlags=t.BamFlags=void 0;const i=n(r(7295)),a={a:0,A:0,c:1,C:1,g:2,G:2,t:3,T:3,n:4,N:4};function A(e){const t={};for(const[r,n]of e)t[`is${n}`]=e=>!!(e&r),t[`set${n}`]=e=>e|r;return t}t.BamFlags=[[1,"Paired"],[2,"ProperlyPaired"],[4,"SegmentUnmapped"],[8,"MateUnmapped"],[16,"ReverseComplemented"],[32,"MateReverseComplemented"],[64,"Read1"],[128,"Read2"],[256,"Secondary"],[512,"FailedQc"],[1024,"Duplicate"],[2048,"Supplementary"]],t.CramFlags=[[1,"PreservingQualityScores"],[2,"Detached"],[4,"WithMateDownstream"],[8,"DecodeSequenceAsStar"]],t.MateFlags=[[1,"OnNegativeStrand"],[2,"Unmapped"]],t.BamFlagsDecoder=A(t.BamFlags),t.CramFlagsDecoder=A(t.CramFlags),t.MateFlagsDecoder=A(t.MateFlags),t.default=class{constructor({flags:e,cramFlags:t,readLength:r,mappingQuality:n,lengthOnRef:i,qualityScores:a,mateRecordNumber:A,readBases:s,readFeatures:o,mateToUse:c,readGroupId:d,readName:l,sequenceId:f,uniqueId:g,templateSize:h,alignmentStart:u,tags:C}){this.flags=e,this.cramFlags=t,this.readLength=r,this.mappingQuality=n,this.lengthOnRef=i,this.qualityScores=a,s&&(this.readBases=s),this.readGroupId=d,this.readName=l,this.sequenceId=f,this.uniqueId=g,this.templateSize=h,this.alignmentStart=u,this.tags=C,o&&(this.readFeatures=o),c&&(this.mate={flags:c.mateFlags,readName:c.mateReadName,sequenceId:c.mateSequenceId,alignmentStart:c.mateAlignmentStart}),A&&(this.mateRecordNumber=A);}isPaired(){return !!(this.flags&i.default.BAM_FPAIRED)}isProperlyPaired(){return !!(this.flags&i.default.BAM_FPROPER_PAIR)}isSegmentUnmapped(){return !!(this.flags&i.default.BAM_FUNMAP)}isMateUnmapped(){return !!(this.flags&i.default.BAM_FMUNMAP)}isReverseComplemented(){return !!(this.flags&i.default.BAM_FREVERSE)}isMateReverseComplemented(){return !!(this.flags&i.default.BAM_FMREVERSE)}isRead1(){return !!(this.flags&i.default.BAM_FREAD1)}isRead2(){return !!(this.flags&i.default.BAM_FREAD2)}isSecondary(){return !!(this.flags&i.default.BAM_FSECONDARY)}isFailedQc(){return !!(this.flags&i.default.BAM_FQCFAIL)}isDuplicate(){return !!(this.flags&i.default.BAM_FDUP)}isSupplementary(){return !!(this.flags&i.default.BAM_FSUPPLEMENTARY)}isDetached(){return !!(this.cramFlags&i.default.CRAM_FLAG_DETACHED)}hasMateDownStream(){return !!(this.cramFlags&i.default.CRAM_FLAG_MATE_DOWNSTREAM)}isPreservingQualityScores(){return !!(this.cramFlags&i.default.CRAM_FLAG_PRESERVE_QUAL_SCORES)}isUnknownBases(){return !!(this.cramFlags&i.default.CRAM_FLAG_NO_SEQ)}getReadBases(){if(!this.readBases&&this._refRegion){const e=function(e,t){if(!e.lengthOnRef&&!e.readLength)return null;if(e.isUnknownBases())return null;const r=e.alignmentStart-t.start;if(!e.readFeatures)return t.seq.slice(r,r+(e.lengthOnRef||0)).toUpperCase();let n="",i=r,a=0;for(;n.length<e.readLength;)if(a<e.readFeatures.length){const r=e.readFeatures[a];if("Q"===r.code||"q"===r.code)a+=1;else if(r.pos===n.length+1)if(a+=1,"b"===r.code){const e=r.data;n+=e,i+=e.length;}else "B"===r.code?(n+=r.data[0],i+=1):"X"===r.code?(n+=r.sub,i+=1):"I"===r.code?n+=r.data:"D"===r.code?i+=r.data:"i"===r.code?n+=r.data:"N"===r.code?i+=r.data:"S"===r.code?n+=r.data:"P"===r.code||r.code;else if(a<e.readFeatures.length){const e=t.seq.slice(i,i+r.pos-n.length-1);n+=e,i+=e.length;}}else {const r=t.seq.slice(i,i+e.readLength-n.length);n+=r,i+=r.length;}return n.toUpperCase()}(this,this._refRegion);e&&(this.readBases=e);}return this.readBases}getPairOrientation(){if(!this.isSegmentUnmapped()&&this.isPaired()&&!this.isMateUnmapped()&&this.mate&&this.sequenceId===this.mate.sequenceId){const e=this.isReverseComplemented()?"R":"F",t=this.isMateReverseComplemented()?"R":"F";let r=" ",n=" ";this.isRead1()?(r="1",n="2"):this.isRead2()&&(r="2",n="1");const i=[];let a=this.templateLength||this.templateSize;if(void 0===a)throw new Error("One of templateSize and templateLength must be set");return this.alignmentStart>this.mate.alignmentStart&&a>0&&(a=-a),a>0?(i[0]=e,i[1]=r,i[2]=t,i[3]=n):(i[2]=e,i[3]=r,i[0]=t,i[1]=n),i.join("")}return null}addReferenceSequence(e,t){this.readFeatures&&this.readFeatures.forEach((r=>{"X"===r.code&&function(e,t,r,n){const i=n.refPos-t.start,A=t.seq.charAt(i);A&&(n.ref=A);let s=a[A];void 0===s&&(s=4);const o=r.substitutionMatrix[s][n.data];o&&(n.sub=o);}(0,e,t,r);})),!this.readBases&&e.start<=this.alignmentStart&&e.end>=this.alignmentStart+(this.lengthOnRef||this.readLength)-1&&(this._refRegion=e);}toJSON(){const e={};return Object.keys(this).forEach((t=>{t.startsWith("_")||(e[t]=this[t]);})),e.readBases=this.getReadBases(),e}};},3165:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.cramFileDefinition=i,t.cramBlockHeader=a,t.cramBlockCrc32=A,t.cramTagDictionary=o,t.cramPreservationMap=c,t.isMappedSliceHeader=function(e){return "number"==typeof e.refSeqId},t.getSectionParsers=function(e){return {cramFileDefinition:i(),cramBlockHeader:a(),cramBlockCrc32:A(),cramDataSeriesEncodingMap:h(),cramTagEncodingMap:u(),cramCompressionHeader:{parser:(e,t)=>{const{value:r,offset:n}=c().parser(e,t);t=n;const{value:i,offset:a}=h().parser(e,t);t=a;const{value:A,offset:s}=u().parser(e,t);return t=s,{value:{dataSeriesEncoding:d(i),preservation:d(r),tagEncoding:d(A)},offset:t}}},cramEncoding:{parser:(e,t)=>g(e,t)},cramUnmappedSliceHeader:l(e),cramMappedSliceHeader:f(e),cramContainerHeader1:C(e),cramContainerHeader2:I(e)}};const n=r(400);function i(){return {parser:(e,t=0)=>{const r=new DataView(e.buffer,e.byteOffset,e.length),n=new TextDecoder("utf8");let i=0;const a=n.decode(e.subarray(i,i+4));i+=4;const A=r.getUint8(i);i+=1;const s=r.getUint8(i);i+=1;const o=n.decode(e.subarray(i,i+20)).replaceAll("\0","");return i+=20,{value:{magic:a,majorVersion:A,minorVersion:s,fileId:o},offset:i}},maxLength:26}}function a(){return {parser:(e,t=0)=>{const r=e,i=new DataView(r.buffer,r.byteOffset,r.length);let a=0;const A=i.getUint8(a),s=["raw","gzip","bzip2","lzma","rans","rans4x16","arith","fqzcomp","tok3"][A];if(!s)throw new Error(`compression method number ${A} not implemented`);a+=1;const o=i.getUint8(a),c=["FILE_HEADER","COMPRESSION_HEADER","MAPPED_SLICE_HEADER","UNMAPPED_SLICE_HEADER","EXTERNAL_DATA","CORE_DATA"][o];if(!c)throw new Error(`invalid block content type id ${o}`);a+=1;const[d,l]=(0, n.parseItf8)(e,a);a+=l;const[f,g]=(0, n.parseItf8)(e,a);a+=g;const[h,u]=(0, n.parseItf8)(e,a);return a+=u,{offset:a,value:{uncompressedSize:h,compressedSize:f,contentId:d,contentType:c,compressionMethod:s}}},maxLength:17}}function A(){return {parser:(e,t)=>{const r=e,n=new DataView(r.buffer,r.byteOffset,r.length).getUint32(t,!0);return {offset:t+=4,value:{crc32:n}}},maxLength:4}}function s(e,t,r){const n=new TextDecoder("utf8").decode(e.subarray(t,r)),i=[];for(let e=0;e<n.length;e+=3)i.push(n.slice(e,e+3));return i}function o(){return {parser:(e,t)=>{const[r,i]=(0, n.parseItf8)(e,t);t+=i;const a=e.subarray(t,t+r);t+=r;const A=[];let o=0,c=0;for(;c<a.length;c++)a[c]||(A.push(s(a,o,c)),o=c+1);return c>o&&A.push(s(a,o,c)),{value:{size:r,ents:A},offset:t}}}}function c(){return {parser:(e,t)=>{const r=e,i=new DataView(r.buffer,r.byteOffset,r.length),[a,A]=(0, n.parseItf8)(e,t);t+=A;const[s,c]=(0, n.parseItf8)(e,t);t+=c;const d=[];for(let r=0;r<s;r++){const r=String.fromCharCode(e[t])+String.fromCharCode(e[t+1]);if(t+=2,"MI"===r||"UI"===r||"PI"===r||"RN"===r||"AP"===r||"RR"===r)d.push({key:r,value:!!i.getUint8(t)}),t+=1;else if("SM"===r)d.push({key:r,value:[i.getUint8(t),i.getUint8(t+1),i.getUint8(t+2),i.getUint8(t+3),i.getUint8(t+4)]}),t+=5;else {if("TD"!==r)throw new Error(`unknown key ${r}`);{const{offset:n,value:i}=o().parser(e,t);d.push({key:r,value:i.ents}),t=n;}}}return {value:{mapSize:a,mapCount:s,ents:d},offset:t}}}}function d(e){const t={};for(const{key:r,value:n}of e.ents)t[r]&&console.warn(`duplicate key ${r} in map`),t[r]=n;return t}function l(e){return {parser:(t,r)=>{const[i,a]=(0, n.parseItf8)(t,r);r+=a;let A=0;if(e>=3){const[e,i]=(0, n.parseLtf8)(t,r);r+=i,A=e;}else if(2===e){const[e,i]=(0, n.parseItf8)(t,r);r+=i,A=e;}else console.warn("recordCounter=0");const[s,o]=(0, n.parseItf8)(t,r);r+=o;const[c,d]=(0, n.parseItf8)(t,r);r+=d;const l=[];for(let e=0;e<c;e++){const[e,i]=(0, n.parseItf8)(t,r);r+=i,l.push(e);}let f;return e>=2&&(f=[...t.subarray(r,r+16)],r+=16),{value:{recordCounter:A,md5:f,contentIds:l,numContentIds:c,numBlocks:s,numRecords:i},offset:r}},maxLength:e=>40+5*e}}function f(e){return {parser:(t,r)=>{const[i,a]=(0, n.parseItf8)(t,r);r+=a;const[A,s]=(0, n.parseItf8)(t,r);r+=s;const[o,c]=(0, n.parseItf8)(t,r);r+=c;const[d,l]=(0, n.parseItf8)(t,r);r+=l;let f=0;if(e>=3){const[e,i]=(0, n.parseLtf8)(t,r);r+=i,f=e;}else if(2===e){const[e,i]=(0, n.parseItf8)(t,r);r+=i,f=e;}else console.warn("majorVersion is <2, recordCounter set to 0");const[g,h]=(0, n.parseItf8)(t,r);r+=h;const[u,C]=(0, n.parseItf8)(t,r);r+=C;const I=[];for(let e=0;e<u;e++){const[e,i]=(0, n.parseItf8)(t,r);r+=i,I.push(e);}const[_,m]=(0, n.parseItf8)(t,r);let B;return r+=m,e>=2&&(B=[...t.subarray(r,r+16)],r+=16),{value:{md5:B,numBlocks:g,numRecords:d,numContentIds:u,refSeqSpan:o,refSeqId:i,refSeqStart:A,recordCounter:f,refBaseBlockId:_,contentIds:I},offset:r}},maxLength:e=>60+5*e}}function g(e,t){const r=e,i=new DataView(r.buffer,r.byteOffset,r.length),[a,A]=(0, n.parseItf8)(e,t);t+=A;const[s,o]=(0, n.parseItf8)(e,t);t+=o;const c={};if(0===a);else if(1===a){const[r,i]=(0, n.parseItf8)(e,t);c.blockContentId=r,t+=i;}else if(2===a){const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;const[a,A]=(0, n.parseItf8)(e,t);c.M=a,t+=A;}else if(3===a){const r=(0, n.parseItf8)(e,t),i=r[0];t+=r[1];const a=[];for(let r=0;r<i;r++){const r=(0, n.parseItf8)(e,t);a.push(r[0]),t+=r[1];}c.symbols=a;const A=(0, n.parseItf8)(e,t),s=r[0];c.numLengths=s,c.numCodes=i,c.numLengths=s,t+=A[1];const o=[];for(let r=0;r<s;r++){const r=(0, n.parseItf8)(e,t);t+=r[1],o.push(r[0]);}c.bitLengths=o;}else if(4===a){const{value:r,offset:n}=g(e,t);c.lengthsEncoding=r,t=n;const{value:i,offset:a}=g(e,t);c.valuesEncoding=i,t=a;}else if(5===a){c.stopByte=i.getUint8(t),t+=1;const[r,a]=(0, n.parseItf8)(e,t);c.blockContentId=r,t+=a;}else if(6===a){const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;const[a,A]=(0, n.parseItf8)(e,t);c.length=a,t+=A;}else if(7===a){const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;const[a,A]=(0, n.parseItf8)(e,t);c.K=a,t+=A;}else if(8===a){const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;const[a,A]=(0, n.parseItf8)(e,t);c.log2m=a,t+=A;}else {if(9!==a)throw new Error(`unknown codecId ${a}`);{const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;}}return {value:{codecId:a,parametersBytes:s,parameters:c},offset:t}}function h(){return {parser:(e,t)=>{const[r,i]=(0, n.parseItf8)(e,t);t+=i;const[a,A]=(0, n.parseItf8)(e,t);t+=A;const s=[];for(let r=0;r<a;r++){const r=String.fromCharCode(e[t])+String.fromCharCode(e[t+1]);t+=2;const{value:n,offset:i}=g(e,t);t=i,s.push({key:r,value:n});}return {value:{mapSize:r,ents:s,mapCount:a},offset:t}}}}function u(){return {parser:(e,t)=>{const[r,i]=(0, n.parseItf8)(e,t);t+=i;const[a,A]=(0, n.parseItf8)(e,t);t+=A;const s=[];for(let r=0;r<a;r++){const[r,i]=(0, n.parseItf8)(e,t);t+=i;const a=String.fromCharCode(r>>16&255)+String.fromCharCode(r>>8&255)+String.fromCharCode(255&r),{value:A,offset:o}=g(e,t);t=o,s.push({key:a,value:A});}return {value:{mapSize:r,ents:s,mapCount:a},offset:t}}}}function C(e){return {maxLength:52,parser:(t,r)=>{const i=t,a=new DataView(i.buffer,i.byteOffset,i.length).getInt32(r,!0);r+=4;const[A,s]=(0, n.parseItf8)(t,r);r+=s;const[o,c]=(0, n.parseItf8)(t,r);r+=c;const[d,l]=(0, n.parseItf8)(t,r);r+=l;const[f,g]=(0, n.parseItf8)(t,r);r+=g;let h,u=0;if(e>=3){const[e,i]=(0, n.parseLtf8)(t,r);u=e,r+=i;}else if(2===e){const[e,i]=(0, n.parseItf8)(t,r);u=e,r+=i;}else console.warn("setting recordCounter=0");if(e>1){const[e,i]=(0, n.parseLtf8)(t,r);h=e,r+=i;}const[C,I]=(0, n.parseItf8)(t,r);r+=I;const[_,m]=(0, n.parseItf8)(t,r);return {value:{length:a,refSeqId:A,refSeqStart:o,alignmentSpan:d,numBlocks:C,numLandmarks:_,numBases:h,recordCounter:u,numRecords:f},offset:r+=m}}}}function I(e){return {parser:(t,r)=>{const i=t,a=new DataView(i.buffer,i.byteOffset,i.length),[A,s]=(0, n.parseItf8)(t,r);r+=s;const o=[];for(let e=0;e<A;e++){const[e,i]=(0, n.parseItf8)(t,r);r+=i,o.push(e);}let c;return e>=3&&(c=a.getUint32(r,!0),r+=4),{value:{...void 0===c?{}:{crc32:c},numLandmarks:A,landmarks:o},offset:r}},maxLength:e=>5+5*e+4}}},6484:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=function(e,t,r,o,c,d,l,f,g){let h=t("BF");const u=t("CF");if(!(0, a.isMappedSliceHeader)(o.parsedContent))throw new Error("slice header not mapped");const C=f>1&&-2===o.parsedContent.refSeqId?t("RI"):o.parsedContent.refSeqId,I=t("RL");let _=t("AP");r.APdelta&&(_+=l.lastAlignmentStart),l.lastAlignmentStart=_;const m=t("RG");let B,p,w,E;if(r.readNamesIncluded&&(B=A(t("RN"))),i.CramFlagsDecoder.isDetached(u)){const e=t("MF");let n;r.readNamesIncluded||(n=A(t("RN")),B=n);const a=t("NS"),s=t("NP");(e||a>-1)&&(p={mateFlags:e,mateSequenceId:a,mateAlignmentStart:s,mateReadName:n}),w=t("TS"),i.MateFlagsDecoder.isUnmapped(e)&&(h=i.BamFlagsDecoder.setMateUnmapped(h)),i.MateFlagsDecoder.isOnNegativeStrand(e)&&(h=i.BamFlagsDecoder.setMateReverseComplemented(h));}else i.CramFlagsDecoder.isWithMateDownstream(u)&&(E=t("NF")+g+1);const Q=t("TL");if(Q<0)throw new n.CramMalformedError("invalid TL index");const y={},b=r.getTagNames(Q),S=b.length;for(let t=0;t<S;t++){const n=b[t],i=n.slice(0,2),a=n.slice(2,3),A=r.getCodecForTag(n).decode(e,c,d,l);y[i]=void 0===A?void 0:"number"==typeof A?A:s(a,A);}let D,k,v,R,F;if(i.BamFlagsDecoder.isSegmentUnmapped(h))if(i.CramFlagsDecoder.isDecodeSequenceAsStar(u))F=null,R=null;else {const e=new Array(I);for(let r=0;r<e.length;r++)e[r]=t("BA");if(F=String.fromCharCode(...e),i.CramFlagsDecoder.isPreservingQualityScores(u)){R=new Array(I);for(let r=0;r<e.length;r++)R[r]=t("QS");}}else {const e=t("FN");if(e&&(D=function(e,t,r,i,a){let A=0,s=e-1;const o=new Array(t);function c([e,t]){const n=r(t);if("character"===e)return String.fromCharCode(n);if("string"===e){let e="";for(let t=0;t<n.byteLength;t++)e+=String.fromCharCode(n[t]);return e}return "numArray"===e?Array.from(n):n}for(let e=0;e<t;e++){const t=String.fromCharCode(r("FC")),i=r("FP"),d={B:["character","BA"],S:["string",a>1?"SC":"IN"],X:["number","BS"],D:["number","DL"],I:["string","IN"],i:["character","BA"],b:["string","BB"],q:["numArray","QQ"],Q:["number","QS"],H:["number","HC"],P:["number","PD"],N:["number","RS"]}[t];if(!d)throw new n.CramMalformedError(`invalid read feature code "${t}"`);let l=c(d);const f={B:["number","QS"]}[t];f&&(l=[l,c(f)]),A+=i;const g=A;s+=i;const h=s;"D"===t||"N"===t?s+=l:"I"===t||"S"===t?s-=l.length:"i"===t&&(s-=1),o[e]={code:t,pos:g,refPos:h,data:l};}return o}(_,e,t,0,f)),k=I,D)for(const{code:e,data:t}of D)"D"===e||"N"===e?k+=t:"I"===e||"S"===e?k-=t.length:"i"===e&&(k-=1);if(Number.isNaN(k)&&(console.warn(`${B||`${C}:${_}`} record has invalid read features`),k=I),v=t("MQ"),i.CramFlagsDecoder.isPreservingQualityScores(u)){R=new Array(I);for(let e=0;e<R.length;e++)R[e]=t("QS");}}return {readLength:I,sequenceId:C,cramFlags:u,flags:h,alignmentStart:_,readGroupId:m,readName:B,mateToUse:p,templateSize:w,mateRecordNumber:E,readFeatures:D,lengthOnRef:k,mappingQuality:v,qualityScores:R,readBases:F,tags:y}};const n=r(9747),i=r(8401),a=r(3165);function A(e){let t="";for(let r=0;r<e.length&&0!==e[r];r++)t+=String.fromCharCode(e[r]);return t}function s(e,t){if("Z"===e)return A(t);if("A"===e)return String.fromCharCode(t[0]);if("I"===e)return new Uint32Array(t.buffer)[0];if("i"===e)return new Int32Array(t.buffer)[0];if("s"===e)return new Int16Array(t.buffer)[0];if("S"===e)return new Uint16Array(t.buffer)[0];if("c"===e)return new Int8Array(t.buffer)[0];if("C"===e)return t[0];if("f"===e)return new Float32Array(t.buffer)[0];if("H"===e)return Number.parseInt(A(t).replace(/^0x/,""),16);if("B"===e)return function(e){const t=String.fromCharCode(e[0]),r=new DataView(e.buffer).getUint32(1,!0),n=new Array(r);if(e=e.slice(5),"c"===t){const t=new Int8Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e];}else if("C"===t){const t=new Uint8Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e];}else if("s"===t){const t=new Int16Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e];}else if("S"===t){const t=new Uint16Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e];}else if("i"===t){const t=new Int32Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e];}else if("I"===t){const t=new Uint32Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e];}else {if("f"!==t)throw new Error(`unknown type: ${t}`);{const t=new Float32Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e];}}return n}(t);throw new n.CramMalformedError(`Unrecognized tag type ${e}`)}},6771:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=r(9747),a=r(612),A=n(r(7295)),s=n(r(6484)),o=n(r(8401)),c=r(3165),d=r(400);function l(e,t,r,n){const a=!!(n.mate||void 0!==n.mateRecordNumber&&n.mateRecordNumber!==t);r.readName||(r.readName=String(r.uniqueId),n.readName=r.readName),r.mate={sequenceId:n.sequenceId,alignmentStart:n.alignmentStart,uniqueId:n.uniqueId},n.readName&&(r.mate.readName=n.readName),n.mate||void 0!==n.mateRecordNumber||(n.mate={sequenceId:r.sequenceId,alignmentStart:r.alignmentStart,uniqueId:r.uniqueId},r.readName&&(n.mate.readName=r.readName)),r.flags|=A.default.BAM_FPAIRED,n.flags&A.default.BAM_FUNMAP&&(r.flags|=A.default.BAM_FMUNMAP),r.flags&A.default.BAM_FUNMAP&&(n.flags|=A.default.BAM_FMUNMAP),n.flags&A.default.BAM_FREVERSE&&(r.flags|=A.default.BAM_FMREVERSE),r.flags&A.default.BAM_FREVERSE&&(n.flags|=A.default.BAM_FMREVERSE),void 0===r.templateLength&&(a?function(e,t,r){const n=function t(r){const n=[r];if(void 0!==r.mateRecordNumber&&r.mateRecordNumber>=0){const a=e[r.mateRecordNumber];if(!a)throw new i.CramMalformedError("intra-slice mate record not found, this file seems malformed");n.push(...t(a));}return n}(r),a=n.map((e=>e.alignmentStart)),A=n.map((e=>e.alignmentStart+e.readLength-1)),s=Math.max(...A)-Math.min(...a)+1;s>=0&&n.forEach((e=>{if(void 0!==e.templateLength)throw new i.CramMalformedError("mate pair group has some members that have template lengths already, this file seems malformed");e.templateLength=s;}));}(e,0,r):function(e,t){const r=Math.min(e.alignmentStart,t.alignmentStart),n=Math.max(e.alignmentStart+e.readLength-1,t.alignmentStart+t.readLength-1)-r+1;e.templateLength=n,t.templateLength=n;}(r,n)),r.mateRecordNumber=void 0;}class f{constructor(e,t,r){this.container=e,this.containerPosition=t,this.sliceSize=r,this.file=e.file;}async getHeader(){const{majorVersion:e}=await this.file.getDefinition(),t=(0, c.getSectionParsers)(e),r=await this.container.getHeader(),n=await this.file.readBlock(r._endPosition+this.containerPosition);if("MAPPED_SLICE_HEADER"===n.contentType){const e=(0, d.parseItem)(n.content,t.cramMappedSliceHeader.parser,0,r._endPosition);return {...n,parsedContent:e}}if("UNMAPPED_SLICE_HEADER"===n.contentType){const e=(0, d.parseItem)(n.content,t.cramUnmappedSliceHeader.parser,0,r._endPosition);return {...n,parsedContent:e}}throw new i.CramMalformedError(`error reading slice header block, invalid content type ${n.contentType}`)}async getBlocks(){const e=await this.getHeader();let t=e._endPosition;const r=new Array(e.parsedContent.numBlocks);for(let e=0;e<r.length;e++){const n=await this.file.readBlock(t);r[e]=n,t=r[e]._endPosition;}return r}async getCoreDataBlock(){return (await this.getBlocks())[0]}async _getBlocksContentIdIndex(){const e=await this.getBlocks(),t={};return e.forEach((e=>{"EXTERNAL_DATA"===e.contentType&&(t[e.contentId]=e);})),t}async getBlockByContentId(e){return (await this._getBlocksContentIdIndex())[e]}async getReferenceRegion(){const e=new TextDecoder("utf8"),t=(await this.getHeader()).parsedContent;if(!(0, c.isMappedSliceHeader)(t))throw new Error("slice header not mapped");if(t.refSeqId<0)return;const r=await this.container.getCompressionScheme();if(void 0===r)throw new Error("compression scheme undefined");if(t.refBaseBlockId>=0){const r=await this.getBlockByContentId(t.refBaseBlockId);if(!r)throw new i.CramMalformedError("embedded reference specified, but reference block does not exist");return {seq:e.decode(r.data),start:t.refSeqStart,end:t.refSeqStart+t.refSeqSpan-1,span:t.refSeqSpan}}if(r.referenceRequired||this.file.fetchReferenceSequenceCallback){if(!this.file.fetchReferenceSequenceCallback)throw new Error("reference sequence not embedded, and seqFetch callback not provided, cannot fetch reference sequence");const e=await this.file.fetchReferenceSequenceCallback(t.refSeqId,t.refSeqStart,t.refSeqStart+t.refSeqSpan-1);if(e.length!==t.refSeqSpan)throw new i.CramArgumentError("seqFetch callback returned a reference sequence of the wrong length");return {seq:e,start:t.refSeqStart,end:t.refSeqStart+t.refSeqSpan-1,span:t.refSeqSpan}}}getAllRecords(){return this.getRecords((()=>!0))}async _fetchRecords(){const{majorVersion:e}=await this.file.getDefinition(),t=await this.container.getCompressionScheme();if(void 0===t)throw new Error("compression scheme undefined");const r=await this.getHeader(),n=await this._getBlocksContentIdIndex();if(e>1&&this.file.options.checkSequenceMD5&&(0, c.isMappedSliceHeader)(r.parsedContent)&&r.parsedContent.refSeqId>=0&&"0000000000000000"!==r.parsedContent.md5?.join("")){const e=await this.getReferenceRegion();if(e){const{seq:t,start:n,end:a}=e,A=(0, d.sequenceMD5)(t),s=r.parsedContent.md5?.map((e=>(e<16?"0":"")+e.toString(16))).join("");if(A!==s)throw new i.CramMalformedError(`MD5 checksum reference mismatch for ref ${r.parsedContent.refSeqId} pos ${n}..${a}. recorded MD5: ${s}, calculated MD5: ${A}`)}}const A=await this.getCoreDataBlock(),f={lastAlignmentStart:(0, c.isMappedSliceHeader)(r.parsedContent)?r.parsedContent.refSeqStart:0,coreBlock:{bitPosition:7,bytePosition:0},externalBlocks:{map:new Map,getCursor(e){let t=this.map.get(e);return void 0===t&&(t={bitPosition:7,bytePosition:0},this.map.set(e,t)),t}}},g=e=>{const r=t.getCodecForDataSeries(e);if(!r)throw new i.CramMalformedError(`no codec defined for ${e} data series`);return r.decode(this,A,n,f)},h=new Array(r.parsedContent.numRecords);for(let i=0;i<h.length;i+=1)try{const a=(0,s.default)(this,g,t,r,A,n,f,e,i);h[i]=new o.default({...a,uniqueId:r.contentPosition+r.parsedContent.recordCounter+i+1});}catch(e){if(e instanceof a.CramBufferOverrunError){console.warn("read attempted beyond end of buffer, file seems truncated.");break}throw e}for(let e=0;e<h.length;e+=1){const t=h[e];if(t){const{mateRecordNumber:r}=t;void 0!==r&&r>=0&&h[r]&&l(h,e,t,h[r]);}}return h}async getRecords(e){const t=this.container.filePosition+this.containerPosition;let r=this.file.featureCache.get(t.toString());r||(r=this._fetchRecords(),this.file.featureCache.set(t.toString(),r));const n=(await r).filter(e);if(n.length&&this.file.fetchReferenceSequenceCallback){const e=await this.getHeader();if((0, c.isMappedSliceHeader)(e.parsedContent)&&(e.parsedContent.refSeqId>=0||-2===e.parsedContent.refSeqId)){const t=e.parsedContent.refSeqId>=0?e.parsedContent.refSeqId:void 0,r=await this.container.getCompressionScheme();if(void 0===r)throw new Error("compression scheme undefined");const i={};for(const e of n){const r=void 0!==t?t:e.sequenceId;let n=i[r];n||(n={id:r,start:e.alignmentStart,end:Number.NEGATIVE_INFINITY,seq:null},i[r]=n);const a=e.alignmentStart+(e.lengthOnRef||e.readLength)-1;a>n.end&&(n.end=a),e.alignmentStart<n.start&&(n.start=e.alignmentStart);}await Promise.all(Object.values(i).map((async e=>{-1!==e.id&&e.start<=e.end&&this.file.fetchReferenceSequenceCallback&&(e.seq=await this.file.fetchReferenceSequenceCallback(e.id,e.start,e.end));})));for(const e of n){const n=i[void 0!==t?t:e.sequenceId];if(n?.seq){const t=n.seq;e.addReferenceSequence({...n,seq:t},r);}}}}return n}}t.default=f,"getHeader getBlocks _getBlocksContentIdIndex".split(" ").forEach((e=>{(0, d.tinyMemoize)(f,e);}));},400:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.TWO_PWR_56_DBL=t.TWO_PWR_24_DBL=t.TWO_PWR_64_DBL=t.TWO_PWR_32_DBL=t.TWO_PWR_16_DBL=void 0,t.itf8Size=function(e){return -128&e?-16384&e?-2097152&e?-268435456&e?5:4:3:2:1},t.parseItf8=function(e,t){let r=t;const n=e[r];let i;return n<128?(i=n,r+=1):n<192?(i=(63&n)<<8|e[r+1],r+=2):n<224?(i=(31&n)<<16|e[r+1]<<8|e[r+2],r+=3):n<240?(i=(15&n)<<24|e[r+1]<<16|e[r+2]<<8|e[r+3],r+=4):(i=(15&n)<<28|e[r+1]<<20|e[r+2]<<12|e[r+3]<<4|15&e[r+4],r+=5),[i,r-t]},t.parseLtf8=function(e,r){let n=r;const i=e[n];let a;return i<128?(a=i,n+=1):i<192?(a=16383&(i<<8|e[n+1]),n+=2):i<224?(a=(63&i)<<16|e[n+1]<<8|e[n+2],n+=3):i<240?(a=(31&i)<<24|e[n+1]<<16|e[n+2]<<8|e[n+3],n+=4):i<248?(a=(15&e[n])*t.TWO_PWR_32_DBL+(e[n+1]<<24|e[n+2]<<16|e[n+3]<<8|e[n+4]),n+=5):i<252?(a=((7&e[n])<<8|e[n+1])*t.TWO_PWR_32_DBL+(e[n+2]<<24|e[n+3]<<16|e[n+4]<<8|e[n+5]),n+=6):i<254?(a=((3&e[n])<<16|e[n+1]<<8|e[n+2])*t.TWO_PWR_32_DBL+(e[n+3]<<24|e[n+4]<<16|e[n+5]<<8|e[n+6]),n+=7):i<255?(a=(e[n+1]<<24|e[n+2]<<16|e[n+3]<<8|e[n+4])*t.TWO_PWR_32_DBL+(e[n+5]<<24|e[n+6]<<16|e[n+7]<<8|e[n+8]),n+=8):(a=e[n+1]*t.TWO_PWR_56_DBL+(e[n+2]<<24|e[n+3]<<16|e[n+4]<<8|e[n+5])*t.TWO_PWR_32_DBL+(e[n+6]<<24|e[n+7]<<16|e[n+8]<<8|e[n+9]),n+=9),[a,n-r]},t.parseItem=function(e,t,r=0,n=0){const{offset:i,value:a}=t(e,r);return {...a,_endPosition:i+n,_size:i-r}},t.tinyMemoize=function(e,t){const r=e.prototype[t],n=`_memo_${t}`;e.prototype[t]=function(){if(!(n in this)){const e=r.call(this);this[n]=e,Promise.resolve(e).catch((()=>{delete this[n];}));}return this[n]};},t.sequenceMD5=function(e){return (0, i.default)(e.toUpperCase().replaceAll(/[^\u0021-\u007e]/g,""))};const i=n(r(3503));t.TWO_PWR_16_DBL=65536,t.TWO_PWR_32_DBL=t.TWO_PWR_16_DBL*t.TWO_PWR_16_DBL,t.TWO_PWR_64_DBL=t.TWO_PWR_32_DBL*t.TWO_PWR_32_DBL,t.TWO_PWR_24_DBL=1<<24,t.TWO_PWR_56_DBL=t.TWO_PWR_24_DBL*t.TWO_PWR_32_DBL;},9747:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.CramArgumentError=t.CramSizeLimitError=t.CramMalformedError=t.CramUnimplementedError=t.CramError=void 0;class r extends Error{}t.CramError=r;class n extends Error{}t.CramUnimplementedError=n,t.CramMalformedError=class extends r{},t.CramSizeLimitError=class extends r{},t.CramArgumentError=class extends r{};},2884:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=r(9995),a=n(r(8175)),A=n(r(5871)),s=n(r(2935));t.default=class{decode(e){return this.stream=new s.default(e),this.decodeStream(this.stream)}decodeStream(e,t=0){const r=this.stream.ReadByte();16&r||(t=this.stream.ReadUint7());let n=t;const i=1&r;if(8&r)return this.decodeStripe(this.stream,t);var a;if(128&r&&([a,n]=this.decodePackMeta(this.stream)),32&r)var A=this.decodeCat(this.stream,n);else A=4&r?this.decodeExt(this.stream,n):64&r?i?this.decodeRLE1(this.stream,n):this.decodeRLE0(this.stream,n):i?this.decode1(this.stream,n):this.decode0(this.stream,n);return 128&r&&(A=this.decodePack(A,a,t)),A}decode0(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new A.default(n),s=new a.default(e);s.RangeStartDecode(e);for(let n=0;n<t;n++)r[n]=i.ModelDecode(e,s);return r}decode1(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new Array(n);for(var s=0;s<n;s++)i[s]=new A.default(n);const o=new a.default(e);o.RangeStartDecode(e);let c=0;for(s=0;s<t;s++)r[s]=i[c].ModelDecode(e,o),c=r[s];return r}decodeExt(e,t){return (0, i.decode)(e.buf.slice(e.pos))}decodeRLE0(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new A.default(n),s=new Array(258);for(var o=0;o<=257;o++)s[o]=new A.default(4);const c=new a.default(e);for(c.RangeStartDecode(e),o=0;o<t;){r[o]=i.ModelDecode(e,c);let t=s[r[o]].ModelDecode(e,c),n=t,a=256;for(;3==t;)t=s[a].ModelDecode(e,c),a=257,n+=t;for(let e=1;e<=n;e++)r[o+e]=r[o];o+=n+1;}return r}decodeRLE1(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new Array(n);for(var s=0;s<n;s++)i[s]=new A.default(n);const o=new Array(258);for(s=0;s<=257;s++)o[s]=new A.default(4);const c=new a.default(e);c.RangeStartDecode(e);let d=0;for(s=0;s<t;){r[s]=i[d].ModelDecode(e,c),d=r[s];let t=o[r[s]].ModelDecode(e,c),n=t,a=256;for(;3==t;)t=o[a].ModelDecode(e,c),a=257,n+=t;for(let e=1;e<=n;e++)r[s+e]=r[s];s+=n+1;}return r}decodePackMeta(e){this.nsym=e.ReadByte();const t=new Array(this.nsym);for(let r=0;r<this.nsym;r++)t[r]=e.ReadByte();return [t,e.ReadUint7()]}decodePack(e,t,r){const n=new Uint8Array(r);if(this.nsym<=1)for(var i=0;i<r;i++)n[i]=t[0];else if(this.nsym<=2){i=0;for(var a=0;i<r;i++){if(i%8==0)var A=e[a++];n[i]=t[1&A],A>>=1;}}else if(this.nsym<=4)for(i=0,a=0;i<r;i++)i%4==0&&(A=e[a++]),n[i]=t[3&A],A>>=2;else {if(!(this.nsym<=16))return e;for(i=0,a=0;i<r;i++)i%2==0&&(A=e[a++]),n[i]=t[15&A],A>>=4;}return n}packMeta(e){const t=new s.default("",0,1024),r=new Array(256);for(var n=0;n<e.length;n++)r[e[n]]=1;var i=0;for(n=0;n<256;n++)r[n]&&(r[n]=++i);for(t.WriteByte(i),n=0;n<256;n++)r[n]&&(t.WriteByte(n),r[n]--);return [t,r,i]}decodeStripe(e,t){const r=e.ReadByte(),n=new Array(r),i=new Array(r);for(var a=0;a<r;a++)n[a]=e.ReadUint7();const A=new Array(r);for(a=0;a<r;a++)i[a]=Math.floor(t/r)+(t%r>a),A[a]=this.decodeStream(e,i[a]);const s=new Uint8Array(t);for(a=0;a<r;a++)for(let e=0;e<i[a];e++)s[e*r+a]=A[a][e];return s}decodeCat(e,t){const r=new Uint8Array(t);for(let n=0;n<t;n++)r[n]=e.ReadByte();return r}};},8175:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(e){this.low=0,this.range=4294967295,this.code=0,this.FFnum=0,this.carry=0,this.cache=0;}RangeStartDecode(e){for(let t=0;t<5;t++)this.code=(this.code<<8)+e.ReadByte();this.code&=4294967295,this.code>>>=0;}RangeGetFrequency(e){return this.range=Math.floor(this.range/e),Math.floor(this.code/this.range)}RangeDecode(e,t,r,n){for(this.code-=t*this.range,this.range*=r;this.range<1<<24;)this.range*=256,this.code=256*this.code+e.ReadByte();}RangeShiftLow(e){if(this.low<4278190080|this.carry){for(e.WriteByte(this.cache+this.carry);this.FFnum;)e.WriteByte(this.carry-1),this.FFnum--;this.cache=this.low>>>24,this.carry=0;}else this.FFnum++;this.low<<=8,this.low>>>=0;}RangeEncode(e,t,r,n){const i=this.low;for(this.range=Math.floor(this.range/n),this.low+=t*this.range,this.low>>>=0,this.range*=r,this.low<i&&(0!=this.carry&&console.log("ERROR: Multiple carry"),this.carry=1);this.range<1<<24;)this.range*=256,this.RangeShiftLow(e);}RangeFinishEncode(e){for(let t=0;t<5;t++)this.RangeShiftLow(e);}};},5871:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(e=256){this.total_freq=e,this.max_sym=e-1,this.S=[],this.F=[];for(let e=0;e<=this.max_sym;e++)this.S[e]=e,this.F[e]=1;}ModelDecode(e,t){const r=t.RangeGetFrequency(this.total_freq);let n=0,i=0;for(;n+this.F[i]<=r;)n+=this.F[i++];t.RangeDecode(e,n,this.F[i],this.total_freq),this.F[i]+=16,this.total_freq+=16,this.total_freq>65519&&this.ModelRenormalise();const a=this.S[i];if(i>0&&this.F[i]>this.F[i-1]){let e=this.F[i];this.F[i]=this.F[i-1],this.F[i-1]=e,e=this.S[i],this.S[i]=this.S[i-1],this.S[i-1]=e;}return a}ModelRenormalise(){this.total_freq=0;for(let e=0;e<=this.max_sym;e++)this.F[e]-=Math.floor(this.F[e]/2),this.total_freq+=this.F[e];}ModelEncode(e,t,r){let n=0;for(var i=0;this.S[i]!=r;i++)n+=this.F[i];if(t.RangeEncode(e,n,this.F[i],this.total_freq),this.F[i]+=16,this.total_freq+=16,this.total_freq>65519&&this.ModelRenormalise(),r=this.S[i],i>0&&this.F[i]>this.F[i-1]){let e=this.F[i];this.F[i]=this.F[i-1],this.F[i-1]=e,e=this.S[i],this.S[i]=this.S[i-1],this.S[i-1]=e;}}};},4373:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.decode=function(e,t){return function(e,t){const r=e.ReadUint7(),n=function(e){const t={max_sym:0};if(5!=e.ReadByte())return void console.error("Invalid FQZComp version number");const r=e.ReadByte(),n=r&u?e.ReadByte():1;let i=r.nparam>1?r.nparam-1:0;const a=new Array(256);if(r&C)i=e.ReadByte(),s(e,a,256);else {for(var A=0;A<n;A++)a[A]=A;for(;A<256;A++)a[A]=n-1;}t.do_rev=r&I,t.stab=a,t.max_sel=i,t.params=new Array(t.nparam);for(let r=0;r<n;r++)t.params[r]=m(e),t.max_sym<t.params[r].max_sym&&(t.max_sym=t.params[r].max_sym);return t}(e);if(!n)return;var A=n.params;const o=new Array(t.length),c=function(e){const t={};t.qual=new Array(65536);for(var r=0;r<65536;r++)t.qual[r]=new a.default(e.max_sym+1);for(t.len=new Array(4),r=0;r<4;r++)t.len[r]=new a.default(256);return t.rev=new a.default(2),t.dup=new a.default(2),e.max_sel>0&&(t.sel=new a.default(e.max_sel+1)),t}(n),d=new i.default(e);d.RangeStartDecode(e);const l=new Uint8Array(r),f={qctx:0,prevq:0,delta:0,p:0,s:0,x:0,len:0,is_dup:0,rec:0};let g=0;for(;g<r;){if(0==f.p){if(B(e,d,n,c,f,o),f.is_dup>0&&c.dup.ModelDecode(e,d)){for(let e=0;e<len;e++)l[g+e]=l[g+e-f.len];g+=f.len,f.p=0;continue}t.push(f.len);var h=(A=n.params[f.x]).context;}const r=c.qual[h].ModelDecode(e,d);l[g++]=A.qmap[r],h=_(A,f,r);}return n.do_rev&&function(e,t,r,n){let i=0,a=0;for(;a<t;){if(r[i]){let t=0,r=n[i]-1;for(;t<r;){const n=e[a+t];e[a+t]=e[a+r],e[a+r]=n,t++,r--;}}a+=n[i++];}}(l,r,o,t),l}(new A.default(e),t)};const i=n(r(8175)),a=n(r(5871)),A=n(r(2935));function s(e,t,r){let n=0,i=0,a=-1;const A=new Array(1024);for(;i<r;){const t=e.ReadByte();if(A[n++]=t,i+=t,t==a){let r=e.ReadByte();for(i+=t*r;r--;)A[n++]=t;}a=t;}let s=0;for(n=0,i=0;i<r;){let e=0;do{var o=A[n++];e+=o;}while(255==o);for(;e--;)t[i++]=s;s++;}}const o=2,c=4,d=8,l=16,f=32,g=64,h=128,u=1,C=2,I=4;function _(e,t,r){let n=e.context;return t.qctx=(t.qctx<<e.qshift)+e.qtab[r],n+=(t.qctx&(1<<e.qbits)-1)<<e.qloc,e.do_pos&&(n+=e.ptab[Math.min(t.p,1023)]<<e.ploc),e.do_delta&&(n+=e.dtab[Math.min(t.delta,255)]<<e.dloc,t.delta+=t.prevq!=r?1:0,t.prevq=r),e.do_sel&&(n+=t.s<<e.sloc),t.p--,65535&n}function m(e){const t={};t.context=e.ReadUint16(),t.pflags=e.ReadByte(),t.do_dedup=t.pflags&o,t.fixed_len=t.pflags&c,t.do_sel=t.pflags&d,t.do_qmap=t.pflags&l,t.do_pos=t.pflags&f,t.do_delta=t.pflags&g,t.do_qtab=t.pflags&h,t.max_sym=e.ReadByte();let r=e.ReadByte();if(t.qbits=r>>4,t.qshift=15&r,r=e.ReadByte(),t.qloc=r>>4,t.sloc=15&r,r=e.ReadByte(),t.ploc=r>>4,t.dloc=15&r,t.qmap=new Array(256),t.pflags&l)for(var n=0;n<t.max_sym;n++)t.qmap[n]=e.ReadByte();else for(n=0;n<256;n++)t.qmap[n]=n;if(t.qtab=new Array(1024),t.qbits>0&&t.pflags&h)s(e,t.qtab,256);else for(n=0;n<256;n++)t.qtab[n]=n;return t.ptab=new Array(1024),t.pflags&f&&s(e,t.ptab,1024),t.dtab=new Array(256),t.pflags&g&&s(e,t.dtab,256),t}function B(e,t,r,n,i,a){i.s=r.max_sel>0?n.sel.ModelDecode(e,t):0,i.x=r.stab[i.s];const A=r.params[i.x];if(A.fixed_len>=0){var s=n.len[0].ModelDecode(e,t);s|=n.len[1].ModelDecode(e,t)<<8,s|=n.len[2].ModelDecode(e,t)<<16,s|=n.len[3].ModelDecode(e,t)<<24,A.fixed_len>0&&(A.fixed_len=-s);}else s=-A.fixed_len;i.len=s,r.do_rev&&(a[i.rec]=n.rev.ModelDecode(e,t)),i.is_dup=0,A.pflags&o&&n.dup.ModelDecode(e,t)&&(i.is_dup=1),i.p=s,i.delta=0,i.qctx=0,i.prevq=0,i.rec++;}},9151:function(e,t,r){var n,i=this&&this.__createBinding||(Object.create?function(e,t,r,n){void 0===n&&(n=r);var i=Object.getOwnPropertyDescriptor(t,r);i&&!("get"in i?!t.__esModule:i.writable||i.configurable)||(i={enumerable:!0,get:function(){return t[r]}}),Object.defineProperty(e,n,i);}:function(e,t,r,n){void 0===n&&(n=r),e[n]=t[r];}),a=this&&this.__setModuleDefault||(Object.create?function(e,t){Object.defineProperty(e,"default",{enumerable:!0,value:t});}:function(e,t){e.default=t;}),A=this&&this.__importStar||(n=function(e){return n=Object.getOwnPropertyNames||function(e){var t=[];for(var r in e)Object.prototype.hasOwnProperty.call(e,r)&&(t[t.length]=r);return t},n(e)},function(e){if(e&&e.__esModule)return e;var t={};if(null!=e)for(var r=n(e),A=0;A<r.length;A++)"default"!==r[A]&&i(t,e,r[A]);return a(t,e),t}),s=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.r4x8_uncompress=function(e){return d.decode(e)},t.r4x16_uncompress=function(e){return l.decode(e)},t.arith_uncompress=function(e){return (new o.default).decode(e)},t.fqzcomp_uncompress=function(e){return c.decode(e,[])},t.tok3_uncompress=function(e){const t=f.decode(e,0,"\0");return Uint8Array.from(Array.from(t).map((e=>e.charCodeAt(0))))};const o=s(r(2884)),c=A(r(4373)),d=A(r(9725)),l=A(r(6194)),f=A(r(680));},2935:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(e,t=0,r=0){0!==r?(this.buf=new Uint8Array(r),this.length=r):(this.buf=e,this.length=e.length),this.dataView=new DataView(this.buf.buffer),this.pos=t;}EOF(){return this.pos>=this.length}ReadData(e){const t=this.buf.slice(this.pos,this.pos+e);return this.pos+=e,t}ReadByte(){const e=this.buf[this.pos];return this.pos++,e}ReadChar(){const e=this.buf[this.pos];return this.pos++,String.fromCharCode(e)}ReadUint16(){let e=this.ReadByte();return e|=this.ReadByte()<<8,e}ReadUint32(){const e=this.dataView.getInt32(this.pos,!0);return this.pos+=4,e}ReadString(){let e,t="";do{e=this.buf[this.pos++],e&&(t+=String.fromCharCode(e));}while(e);return t}ReadUint7(){let e,t=0;do{e=this.ReadByte(),t=t<<7|127&e;}while(128&e);return t}ReadITF8(){let e=this.buf[this.pos];return this.pos++,e>=240?(e=(15&e)<<28,e+=(this.buf[this.pos+0]<<20)+(this.buf[this.pos+1]<<12)+(this.buf[this.pos+2]<<4)+(this.buf[this.pos+3]>>4),this.pos+=4):e>=224?(e=(15&e)<<24,e+=(this.buf[this.pos+0]<<16)+(this.buf[this.pos+1]<<8)+(0|this.buf[this.pos+2]),this.pos+=3):e>=192?(e=(31&e)<<16,e+=(this.buf[this.pos+0]<<8)+(0|this.buf[this.pos+1]),this.pos+=2):e>=128&&(e=(63&e)<<8,e+=this.buf[this.pos],this.pos++),e}};},9725:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.decode=function(e){const t=new i.default(e),r=t.ReadByte(),n=(t.ReadUint32(),t.ReadUint32());return 0==r?function(e,t){const r=new Array(256),n=new Array(256);d(e,r,n);const i=s(n),A=new Array(4);for(var l=0;l<4;l++)A[l]=e.ReadUint32();const f=new Uint8Array(t);for(l=0;l<t;l++){const t=l%4,s=i[a(A[t])];f[l]=s,A[t]=o(A[t],n[s],r[s]),A[t]=c(e,A[t]);}return f}(t,n):function(e,t){const r=new Array(256),n=new Array(256);!function(e,t,r){for(let e=0;e<256;e++){t[e]=new Array(256),r[e]=new Array(256);for(let r=0;r<256;r++)t[e][r]=0;}let n=e.ReadByte(),i=n,a=0;do{d(e,t[n],r[n]),a>0?(a--,n++):(n=e.ReadByte(),n==i+1&&(a=e.ReadByte())),i=n;}while(0!=n)}(e,r,n);const i=new Array(256);for(var l=0;l<256;l++)i[l]=s(n[l]);const f=new Array(4),g=new Array(4);for(var h=0;h<4;h++)f[h]=e.ReadUint32(),g[h]=0;const u=new Uint8Array(t),C=Math.floor(t/4);for(l=0;l<C;l++)for(h=0;h<4;h++){var I=a(f[h]),_=i[g[h]][I];u[l+h*C]=_,f[h]=o(f[h],n[g[h]][_],r[g[h]][_]),f[h]=c(e,f[h]),g[h]=_;}for(l*=4;l<t;)I=a(f[3]),_=A(n[g[3]],I),u[l++]=_,f[3]=o(f[3],n[g[3]][_],r[g[3]][_]),f[3]=c(e,f[3]),g[3]=_;return u}(t,n)};const i=n(r(2935));function a(e){return 4095&e}function A(e,t){let r=0;for(;t>=e[r+1];)r++;return r}function s(e){const t=new Array(4096);let r=0;for(let n=0;n<4096;n++){for(;n>=e[r+1];)r++;t[n]=r;}return t}function o(e,t,r){return r*(e>>12)+(4095&e)-t}function c(e,t){for(;t<1<<23;)t=(t<<8)+e.ReadByte();return t}function d(e,t,r){for(var n=0;n<256;n++)t[n]=0;let i=e.ReadByte(),a=i,A=0;do{const r=e.ReadITF8();t[i]=r,A>0?(A--,i++):(i=e.ReadByte(),i==a+1&&(A=e.ReadByte())),a=i;}while(0!=i);for(r[0]=0,n=0;n<=255;n++)r[n+1]=r[n]+t[n];}},6194:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.decode=function(e){return d(new i.default(e),0)};const i=n(r(2935));function a(e,t){return e&(1<<t)-1}function A(e,t){let r=0;for(;t>=e[r+1];)r++;return r}function s(e,t){const r=1<<t,n=new Array(r);let i=0;for(let t=0;t<r;t++){for(;t>=e[i+1];)i++;n[t]=i;}return n}function o(e,t,r,n){return r*(e>>n)+(e&(1<<n)-1)-t}function c(e,t){return t<32768&&(t=(t<<16)+e.ReadUint16()),t}function d(e,t){const r=e.ReadByte(),n=1&r,h=8&r,u=32&r,C=64&r,I=128&r,_=4&r?32:4;if(16&r||(t=e.ReadUint7()),h)return function(e,t){const r=e.ReadByte(),n=new Array(r),i=new Array(r);for(var a=0;a<r;a++)n[a]=e.ReadUint7();const A=new Array(r);for(a=0;a<r;a++)i[a]=Math.floor(t/r)+(t%r>a),A[a]=d(e,i[a]);const s=new Uint8Array(t);for(a=0;a<r;a++)for(let e=0;e<i[a];e++)s[e*r+a]=A[a][e];return s}(e,t);if(I)var m=t,[B,p,t]=function(e){const t=e.ReadByte(),r=new Array(t);for(let n=0;n<t;n++)r[n]=e.ReadByte();return [r,t,e.ReadUint7()]}(e);if(C)var w=t,[E,Q,t]=function(e,t){const r=e.ReadUint7(),n=e.ReadUint7();if(1&r)var a=e.ReadData((r-1)/2);else {const n=e.ReadUint7();a=e.ReadData(n),a=f(new i.default(a),r/2,t);}a=new i.default(a);const A=new Array(256);let s=a.ReadByte();0==s&&(s=256);for(let e=0;e<s;e++)A[a.ReadByte()]=1;return [A,a,n]}(e,_);if(u)var y=e.ReadData(t);else y=0==n?f(e,t,_):function(e,t,r){const n=(h=e.ReadByte())>>4;var d=e;if(1&h){const t=e.ReadUint7(),r=e.ReadUint7();var h=new i.default(e.ReadData(r));d=new i.default(f(h,t,4));}const u=new Array(256),C=new Array(256);!function(e,t,r,n){for(var i=0;i<256;i++){t[i]=new Array(256),r[i]=new Array(256);for(var a=0;a<256;a++)t[i][a]=0;}const A=l(e);for(i=0;i<256;i++){if(!A[i])continue;let s=0;for(a=0;a<256;a++)A[a]&&(s>0?s--:(t[i][a]=e.ReadUint7(),0==t[i][a]&&(s=e.ReadByte())));for(g(t[i],n),r[i][0]=0,a=0;a<256;a++)r[i][a+1]=r[i][a]+t[i][a];}}(d,u,C,n);const I=new Array(256);for(var _=0;_<256;_++)I[_]=s(C[_],n);const m=new Array(r),B=new Array(r);for(var p=0;p<r;p++)m[p]=e.ReadUint32(),B[p]=0;const w=new Uint8Array(t),E=Math.floor(t/r);for(_=0;_<E;_++)for(p=0;p<r;p++){var Q=a(m[p],n),y=I[B[p]][Q];w[_+p*E]=y,m[p]=o(m[p],C[B[p]][y],u[B[p]][y],n),m[p]=c(e,m[p]),B[p]=y;}for(_*=r;_<t;)Q=a(m[r-1],n),y=A(C[B[r-1]],Q),w[_++]=y,m[r-1]=o(m[r-1],C[B[r-1]][y],u[B[r-1]][y],n),m[r-1]=c(e,m[r-1]),B[r-1]=y;return w}(e,t,_);return C&&(y=function(e,t,r,n){new i.default(e);const a=new Uint8Array(n);let A=0;for(let i=0;A<n;i++){const n=e[i];if(t[n]){const e=r.ReadUint7();for(let t=0;t<=e;t++)a[A++]=n;}else a[A++]=n;}return a}(y,E,Q,w)),I&&(y=function(e,t,r,n){const i=new Uint8Array(n);let a=0;if(r<=1)for(var A=0;A<n;A++)i[A]=t[0];else if(r<=2)for(A=0;A<n;A++){if(A%8==0)var s=e[a++];i[A]=t[1&s],s>>=1;}else if(r<=4)for(A=0;A<n;A++)A%4==0&&(s=e[a++]),i[A]=t[3&s],s>>=2;else if(r<=16)for(A=0;A<n;A++)A%2==0&&(s=e[a++]),i[A]=t[15&s],s>>=4;return i}(y,B,p,m)),y}function l(e){const t=new Array(256);for(let e=0;e<256;e++)t[e]=0;let r=0,n=e.ReadByte(),i=n;do{t[n]=1,r>0?(r--,n++):(n=e.ReadByte(),n==i+1&&(r=e.ReadByte())),i=n;}while(0!=n);return t}function f(e,t,r){const n=new Array(256),i=new Array(256);!function(e,t,r){for(var n=0;n<256;n++)t[n]=0;const i=l(e);for(n=0;n<256;n++)i[n]>0&&(t[n]=e.ReadUint7());for(g(t,12),r[0]=0,n=0;n<=255;n++)r[n+1]=r[n]+t[n];}(e,n,i);const A=s(i,12),d=new Array(r);for(var f=0;f<r;f++)d[f]=e.ReadUint32();const h=new Uint8Array(t);for(f=0;f<t;f++){const t=f&r-1,s=A[a(d[t],12)];h[f]=s,d[t]=o(d[t],i[s],n[s],12),d[t]=c(e,d[t]);}return h}function g(e,t){let r=0;for(var n=0;n<256;n++)r+=e[n];if(0==r||r==1<<t)return;let i=0;for(;r<1<<t;)r*=2,i++;for(n=0;n<256;n++)e[n]<<=i;}},680:function(e,t,r){var n,i=this&&this.__createBinding||(Object.create?function(e,t,r,n){void 0===n&&(n=r);var i=Object.getOwnPropertyDescriptor(t,r);i&&!("get"in i?!t.__esModule:i.writable||i.configurable)||(i={enumerable:!0,get:function(){return t[r]}}),Object.defineProperty(e,n,i);}:function(e,t,r,n){void 0===n&&(n=r),e[n]=t[r];}),a=this&&this.__setModuleDefault||(Object.create?function(e,t){Object.defineProperty(e,"default",{enumerable:!0,value:t});}:function(e,t){e.default=t;}),A=this&&this.__importStar||(n=function(e){return n=Object.getOwnPropertyNames||function(e){var t=[];for(var r in e)Object.prototype.hasOwnProperty.call(e,r)&&(t[t.length]=r);return t},n(e)},function(e){if(e&&e.__esModule)return e;var t={};if(null!=e)for(var r=n(e),A=0;A<r.length;A++)"default"!==r[A]&&i(t,e,r[A]);return a(t,e),t}),s=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.decode=function(e,t,r){(e=new d.default(e)).ReadUint32();const n=e.ReadUint32(),i=e.ReadByte(),a=function(e,t,r,n){let i=-1;const a=new Array(256);for(;!e.EOF();){const t=e.ReadByte(),A=128&t,s=64&t,c=63&t;if(A&&(i++,a[i]=new Array(13)),c!=g&&A){const e=new Array(n-1).fill(w);a[i][g]=new d.default((0, o.concatUint8Array)([new Uint8Array(c),e]));}if(s){const t=e.ReadByte(),r=e.ReadByte();a[i][c]=new d.default(a[t][r].buf);}else {const t=e.ReadUint7(),n=e.ReadData(t);a[i][c]=r?f.decode(n):l.decode(n),a[i][c]=new d.default(a[i][c]);}}return a}(e,0,i,n),A=new Array(n),s=new Array(n);let c="";void 0===r&&(r="\n");for(let e=0;e<n;e++)c+=y(a,A,s,e)+r;return c};const o=r(3472),c=s(r(2884)),d=s(r(2935)),l=A(r(6194)),f=new c.default,g=0,h=1,u=2,C=3,I=4,_=5,m=7,B=8,p=9,w=10,E=12;function Q(e,t){let r=e+"";for(;r.length<t;)r="0"+r;return r}function y(e,t,r,n){let i=e[0][g].ReadByte();const a=n-e[0][i].ReadUint32();if(i==_)return t[n]=t[a],r[n]=r[a],t[n];let A=1;t[n]="",r[n]=new Array(256);do{switch(i=e[A][g].ReadByte(),i){case u:r[n][A]=e[A][u].ReadChar();break;case h:r[n][A]=e[A][h].ReadString();break;case m:r[n][A]=e[A][m].ReadUint32();break;case C:var s=e[A][C].ReadUint32(),o=e[A][I].ReadByte();r[n][A]=Q(s,o);break;case B:r[n][A]=(0|r[a][A])+e[A][B].ReadByte();break;case p:s=(0|r[a][A])+e[A][p].ReadByte(),o=r[a][A].length,r[n][A]=Q(s,o);break;case w:r[n][A]=r[a][A];break;default:r[n][A]="";}t[n]+=r[n][A++];}while(i!=E);return t[n]}},7806:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.IndexedCramFile=t.CraiIndex=t.CramFile=t.CramRecord=void 0;var i=r(7390);Object.defineProperty(t,"CramRecord",{enumerable:!0,get:function(){return i.CramRecord}}),Object.defineProperty(t,"CramFile",{enumerable:!0,get:function(){return n(i).default}});var a=r(4923);Object.defineProperty(t,"CraiIndex",{enumerable:!0,get:function(){return n(a).default}});var A=r(6014);Object.defineProperty(t,"IndexedCramFile",{enumerable:!0,get:function(){return n(A).default}});},6014:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(7390)),a=r(9747);t.default=class{constructor(e){if(this.cram=e.cram??new i.default({url:e.cramUrl,path:e.cramPath,filehandle:e.cramFilehandle,seqFetch:e.seqFetch,checkSequenceMD5:e.checkSequenceMD5,cacheSize:e.cacheSize}),!(this.cram instanceof i.default))throw new Error("invalid arguments: no cramfile");this.index=e.index;}async getRecordsForRange(e,t,r,n={}){if(n.viewAsPairs=n.viewAsPairs||!1,n.pairAcrossChr=n.pairAcrossChr||!1,n.maxInsertSize=n.maxInsertSize||2e5,"string"==typeof e)throw new a.CramUnimplementedError("string sequence names not yet supported");const i=e,A=await this.index.getEntriesForRange(i,t,r),s=await Promise.all(A.map((n=>this.getRecordsInSlice(n,(n=>n.sequenceId===e&&n.alignmentStart<=r&&void 0!==n.lengthOnRef&&n.alignmentStart+n.lengthOnRef-1>=t)))));let o=Array.prototype.concat(...s);if(n.viewAsPairs){const e={},t={};for(const r of o){const n=r.readName;if(void 0===n)throw new Error("readName undefined");const i=r.uniqueId;e[n]||(e[n]=0),e[n]+=1,t[i]=1;}const r={};Object.entries(e).forEach((([e,t])=>{1===t&&(r[e]=!0);}));const a=[];for(const e of o){const t=e.readName;if(void 0===t)throw new Error("readName undefined");if(r[t]&&e.mate&&(e.mate.sequenceId===i||n.pairAcrossChr)&&Math.abs(e.alignmentStart-e.mate.alignmentStart)<n.maxInsertSize){const t=this.index.getEntriesForRange(e.mate.sequenceId,e.mate.alignmentStart,e.mate.alignmentStart+1);a.push(t);}}const A=await Promise.all(a);let s=[];for(const e of A)s.push(...e);s=s.sort(((e,t)=>e.toString().localeCompare(t.toString()))).filter(((e,t,r)=>!t||e.toString()!==r[t-1].toString()));const d=[];for(const e of s){let n=this.cram.featureCache.get(e.toString());n||(n=this.getRecordsInSlice(e,(()=>!0)),this.cram.featureCache.set(e.toString(),n));const i=n.then((e=>{const n=[];for(const i of e){if(void 0===i.readName)throw new Error("readName undefined");r[i.readName]&&!t[i.uniqueId]&&n.push(i);}return n}));d.push(i);}const l=await Promise.all(d);if(l.length){const e=l.reduce(((e,t)=>e.concat(t)));o=o.concat(e);}}return o}getRecordsInSlice({containerStart:e,sliceStart:t,sliceBytes:r},n){return this.cram.getContainerAtPosition(e).getSlice(t,r).getRecords(n)}hasDataForReferenceSequence(e){return this.index.hasDataForReferenceSequence(e)}};},5931:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.RemoteFile=t.LocalFile=void 0,t.open=function(e,t,r){if(r)return r;if(e)return new n.RemoteFile(e);if(t)return new n.LocalFile(t);throw new Error("no url, path, or filehandle provided, cannot open")};const n=r(689);var i=r(689);Object.defineProperty(t,"LocalFile",{enumerable:!0,get:function(){return i.LocalFile}}),Object.defineProperty(t,"RemoteFile",{enumerable:!0,get:function(){return i.RemoteFile}});},6476:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.TOTFREQ=t.TF_SHIFT=t.RANS_BYTE_L=void 0,t.TF_SHIFT=12,t.TOTFREQ=4096,t.RANS_BYTE_L=1<<23;},997:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.default=function(e,t,r,n){let s=e.getInt(),o=e.getInt(),c=e.getInt(),d=e.getInt();const l=n.remaining(),f=-4&l;for(let i=0;i<f;i+=4){const l=t.R[A.default.get(s,a.TF_SHIFT)],f=t.R[A.default.get(o,a.TF_SHIFT)],g=t.R[A.default.get(c,a.TF_SHIFT)],h=t.R[A.default.get(d,a.TF_SHIFT)];n.putAt(i,l),n.putAt(i+1,f),n.putAt(i+2,g),n.putAt(i+3,h),s=A.default.advanceSymbolStep(s,r[255&l],a.TF_SHIFT),o=A.default.advanceSymbolStep(o,r[255&f],a.TF_SHIFT),c=A.default.advanceSymbolStep(c,r[255&g],a.TF_SHIFT),d=A.default.advanceSymbolStep(d,r[255&h],a.TF_SHIFT),s=A.default.renormalize(s,e),o=A.default.renormalize(o,e),c=A.default.renormalize(c,e),d=A.default.renormalize(d,e);}let g;switch(n.setPosition(f),3&l){case 0:break;case 1:g=t.R[A.default.get(s,a.TF_SHIFT)],A.default.advanceSymbol(s,e,r[255&g],a.TF_SHIFT),n.put(g);break;case 2:g=t.R[A.default.get(s,a.TF_SHIFT)],A.default.advanceSymbol(s,e,r[255&g],a.TF_SHIFT),n.put(g),g=t.R[A.default.get(o,a.TF_SHIFT)],A.default.advanceSymbol(o,e,r[255&g],a.TF_SHIFT),n.put(g);break;case 3:g=t.R[A.default.get(s,a.TF_SHIFT)],A.default.advanceSymbol(s,e,r[255&g],a.TF_SHIFT),n.put(g),g=t.R[A.default.get(o,a.TF_SHIFT)],A.default.advanceSymbol(o,e,r[255&g],a.TF_SHIFT),n.put(g),g=t.R[A.default.get(c,a.TF_SHIFT)],A.default.advanceSymbol(c,e,r[255&g],a.TF_SHIFT),n.put(g);break;default:throw new i.CramMalformedError("invalid output size encountered during rANS decoding")}n.setPosition(0);};const i=r(9747),a=r(6476),A=n(r(488));},7960:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.default=function(e,t,r,n){const A=t.remaining();let s=e.getInt(),o=e.getInt(),c=e.getInt(),d=e.getInt();const l=A>>2;let f=0,g=l,h=2*l,u=3*l,C=0,I=0,_=0,m=0;for(;f<l;f+=1,g+=1,h+=1,u+=1){const A=255&r[C].R[a.default.get(s,i.TF_SHIFT)],l=255&r[I].R[a.default.get(o,i.TF_SHIFT)],B=255&r[_].R[a.default.get(c,i.TF_SHIFT)],p=255&r[m].R[a.default.get(d,i.TF_SHIFT)];t.putAt(f,A),t.putAt(g,l),t.putAt(h,B),t.putAt(u,p),s=a.default.advanceSymbolStep(s,n[C][A],i.TF_SHIFT),o=a.default.advanceSymbolStep(o,n[I][l],i.TF_SHIFT),c=a.default.advanceSymbolStep(c,n[_][B],i.TF_SHIFT),d=a.default.advanceSymbolStep(d,n[m][p],i.TF_SHIFT),s=a.default.renormalize(s,e),o=a.default.renormalize(o,e),c=a.default.renormalize(c,e),d=a.default.renormalize(d,e),C=A,I=l,_=B,m=p;}for(;u<A;u+=1){const A=255&r[m].R[a.default.get(d,i.TF_SHIFT)];t.putAt(u,A),d=a.default.advanceSymbol(d,e,n[m][A],i.TF_SHIFT),m=A;}};const i=r(6476),a=n(r(488));},488:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0});const n=r(9747),i=r(6476);class a{constructor(){this.F=void 0,this.C=void 0;}}function A(e,t,r,n){return r*(e>>n)+(e&(1<<n)-1)-t}t.default={FC:a,AriDecoder:class{constructor(){this.fc=new Array(256);for(let e=0;e<this.fc.length;e+=1)this.fc[e]=new a;this.R=null;}},DecodingSymbol:class{constructor(){this.start=void 0,this.freq=void 0;}},symbolInit:function(e,t,r){if(!(t<=65536))throw new n.CramMalformedError("assertion failed: start <= 1<<16");if(!(r<=65536-t))throw new n.CramMalformedError("assertion failed: freq <= 1<<16");e.start=t,e.freq=r;},advanceStep:A,advanceSymbolStep:function(e,t,r){return A(e,t.start,t.freq,r)},get:function(e,t){return e&(1<<t)-1},advanceSymbol:function(e,t,r,n){return function(e,t,r,n,a){if((e=n*(e>>a)+(e&(1<<a)-1)-r)<i.RANS_BYTE_L)do{e=e<<8|255&t.get();}while(e<i.RANS_BYTE_L);return e}(e,t,r.start,r.freq,n)},renormalize:function(e,t){if(e<i.RANS_BYTE_L)do{e=e<<8|255&t.get();}while(e<i.RANS_BYTE_L);return e}};},1971:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.readStatsO0=function(e,t,r){let n=0,i=0,o=255&e.get();do{null==t.fc[o]&&(t.fc[o]=new A.default.FC),t.fc[o].F=255&e.get(),t.fc[o].F>=128&&(t.fc[o].F&=-129,t.fc[o].F=(127&t.fc[o].F)<<8|255&e.get()),t.fc[o].C=i,A.default.symbolInit(r[o],t.fc[o].C,t.fc[o].F),t.R||(t.R=new Array(a.TOTFREQ)),t.R.fill(o,i,i+t.fc[o].F),i+=t.fc[o].F,0===n&&o+1===(255&e.getByteAt(e.position()))?(o=255&e.get(),n=255&e.get()):0!==n?(n-=1,o+=1):o=255&e.get();}while(0!==o);s(i<a.TOTFREQ);},t.readStatsO1=function(e,t,r){let n=0,i=255&e.get();do{let o=0,c=0,d=255&e.get();null==t[i]&&(t[i]=new A.default.AriDecoder);do{null==t[i].fc[d]&&(t[i].fc[d]=new A.default.FC),t[i].fc[d].F=255&e.get(),t[i].fc[d].F>=128&&(t[i].fc[d].F&=-129,t[i].fc[d].F=(127&t[i].fc[d].F)<<8|255&e.get()),t[i].fc[d].C=c,0===t[i].fc[d].F&&(t[i].fc[d].F=a.TOTFREQ),null==r[i][d]&&(r[i][d]=new A.default.RansDecSymbol),A.default.symbolInit(r[i][d],t[i].fc[d].C,t[i].fc[d].F),null==t[i].R&&(t[i].R=new Array(a.TOTFREQ)),t[i].R.fill(d,c,c+t[i].fc[d].F),c+=t[i].fc[d].F,s(c<=a.TOTFREQ),0===o&&d+1===(255&e.getByteAt(e.position()))?(d=255&e.get(),o=255&e.get()):0!==o?(o-=1,d+=1):d=255&e.get();}while(0!==d);0===n&&i+1===(255&e.getByteAt(e.position()))?(i=255&e.get(),n=255&e.get()):0!==n?(n-=1,i+=1):i=255&e.get();}while(0!==i)};const i=r(9747),a=r(6476),A=n(r(488));function s(e){if(!e)throw new i.CramMalformedError("assertion failed")}},9989:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.default=function(e,t,r=0){if(0===e.length)return t.fill(0),t;const n=new d(e,r),l=n.get();if(0!==l&&1!==l)throw new i.CramMalformedError(`Invalid rANS order ${l}`);if(n.getInt()!==n.remaining()-c)throw new i.CramMalformedError("Incorrect input length.");const f=n.getInt(),g=new d(t||new Uint8Array(f));if(g.length<f)throw new i.CramMalformedError(`Output buffer too small to fit ${f} bytes.`);switch(l){case 0:return function(e,t){const r=new s.default.AriDecoder,n=new Array(256);for(let e=0;e<n.length;e+=1)n[e]=new s.default.DecodingSymbol;return (0, o.readStatsO0)(e,r,n),(0, a.default)(e,r,n,t),t}(n,g);case 1:return function(e,t){const r=new Array(256);for(let e=0;e<r.length;e+=1)r[e]=new s.default.AriDecoder;const n=new Array(256);for(let e=0;e<n.length;e+=1){n[e]=new Array(256);for(let t=0;t<n[e].length;t+=1)n[e][t]=new s.default.DecodingSymbol;}return (0, o.readStatsO1)(e,r,n),(0, A.default)(e,t,r,n),t}(n,g);default:throw new i.CramMalformedError(`Invalid rANS order: ${l}`)}};const i=r(9747),a=n(r(997)),A=n(r(7960)),s=n(r(488)),o=r(1971),c=4;class d{constructor(e,t=0){this._buffer=e,this._dataView=new DataView(e.buffer),this._position=t,this.length=e.length;}get(){const e=this._buffer[this._position];return this._position+=1,e}getByte(){return this.get()}getByteAt(e){return this._buffer[e]}position(){return this._position}put(e){return this._buffer[this._position]=e,this._position+=1,e}putAt(e,t){return this._buffer[e]=t,t}setPosition(e){return this._position=e,e}getInt(){const e=this._dataView.getInt32(this._position,!0);return this._position+=4,e}remaining(){return this._buffer.length-this._position}}},5417:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.parseHeaderText=function(e){const t=e.split(/\r?\n/),r=[];for(const e of t){const[t,...n]=e.split(/\t/);t&&r.push({tag:t.slice(1),data:n.map((e=>{const t=e.indexOf(":");return -1!==t?{tag:e.slice(0,t),value:e.slice(t+1)}:{tag:e,value:""}}))});}return r};},2683:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0});const n=r(6305),i=[0,1,3,7,15,31,63,127,255];t.default=class{constructor(e){this.stream=e,this.bitOffset=0,this.curByte=0,this.hasByte=!1;}_ensureByte(){this.hasByte||(this.curByte=this.stream.readByte(),this.hasByte=!0);}read(e){let t=0;for(;e>0;){this._ensureByte();const r=8-this.bitOffset;if(e>=r)t<<=r,t|=i[r]&this.curByte,this.hasByte=!1,this.bitOffset=0,e-=r;else {t<<=e;const n=r-e;t|=(this.curByte&i[e]<<n)>>n,this.bitOffset+=e,e=0;}}return t}seek(e){const t=e%8,r=(e-t)/8;this.bitOffset=t,this.stream.seek(r),this.hasByte=!1;}pi(){const e=new Uint8Array(6);for(let t=0;t<e.length;t++)e[t]=this.read(8);return (0, n.toHex)(e)}};},9092:e=>{e.exports=function(){const e=new Uint32Array([0,79764919,159529838,222504665,319059676,398814059,445009330,507990021,638119352,583659535,797628118,726387553,890018660,835552979,1015980042,944750013,1276238704,1221641927,1167319070,1095957929,1595256236,1540665371,1452775106,1381403509,1780037320,1859660671,1671105958,1733955601,2031960084,2111593891,1889500026,1952343757,2552477408,2632100695,2443283854,2506133561,2334638140,2414271883,2191915858,2254759653,3190512472,3135915759,3081330742,3009969537,2905550212,2850959411,2762807018,2691435357,3560074640,3505614887,3719321342,3648080713,3342211916,3287746299,3467911202,3396681109,4063920168,4143685023,4223187782,4286162673,3779000052,3858754371,3904687514,3967668269,881225847,809987520,1023691545,969234094,662832811,591600412,771767749,717299826,311336399,374308984,453813921,533576470,25881363,88864420,134795389,214552010,2023205639,2086057648,1897238633,1976864222,1804852699,1867694188,1645340341,1724971778,1587496639,1516133128,1461550545,1406951526,1302016099,1230646740,1142491917,1087903418,2896545431,2825181984,2770861561,2716262478,3215044683,3143675388,3055782693,3001194130,2326604591,2389456536,2200899649,2280525302,2578013683,2640855108,2418763421,2498394922,3769900519,3832873040,3912640137,3992402750,4088425275,4151408268,4197601365,4277358050,3334271071,3263032808,3476998961,3422541446,3585640067,3514407732,3694837229,3640369242,1762451694,1842216281,1619975040,1682949687,2047383090,2127137669,1938468188,2001449195,1325665622,1271206113,1183200824,1111960463,1543535498,1489069629,1434599652,1363369299,622672798,568075817,748617968,677256519,907627842,853037301,1067152940,995781531,51762726,131386257,177728840,240578815,269590778,349224269,429104020,491947555,4046411278,4126034873,4172115296,4234965207,3794477266,3874110821,3953728444,4016571915,3609705398,3555108353,3735388376,3664026991,3290680682,3236090077,3449943556,3378572211,3174993278,3120533705,3032266256,2961025959,2923101090,2868635157,2813903052,2742672763,2604032198,2683796849,2461293480,2524268063,2284983834,2364738477,2175806836,2238787779,1569362073,1498123566,1409854455,1355396672,1317987909,1246755826,1192025387,1137557660,2072149281,2135122070,1912620623,1992383480,1753615357,1816598090,1627664531,1707420964,295390185,358241886,404320391,483945776,43990325,106832002,186451547,266083308,932423249,861060070,1041341759,986742920,613929101,542559546,756411363,701822548,3316196985,3244833742,3425377559,3370778784,3601682597,3530312978,3744426955,3689838204,3819031489,3881883254,3928223919,4007849240,4037393693,4100235434,4180117107,4259748804,2310601993,2373574846,2151335527,2231098320,2596047829,2659030626,2470359227,2550115596,2947551409,2876312838,2788305887,2733848168,3165939309,3094707162,3040238851,2985771188]);return function(){let t=4294967295;this.getCRC=function(){return ~t>>>0},this.updateCRC=function(r){t=t<<8^e[255&(t>>>24^r)];},this.updateCRCRun=function(r,n){for(;n-- >0;)t=t<<8^e[255&(t>>>24^r)];};}}();},9995:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.decode=function(e,t,r){const n=f(e),i=g(t),a=new l(n,i);for(;!("eof"in n)||!n.eof();)if(a._init_block())a._read_bunzip();else {const e=a.reader.read(32)>>>0;if(e!==a.streamCRC&&d(o.DATA_ERROR,"Bad stream CRC (got "+a.streamCRC.toString(16)+" expected "+e.toString(16)+")"),!r||!("eof"in n)||n.eof())break;a._start_bunzip(n,i);}if("getBuffer"in i)return i.getBuffer()};const i=n(r(2683)),a=n(r(9092)),A=n(r(4271)),s=function(e,t){const r=e[t];for(let r=t;r>0;r--)e[r]=e[r-1];return e[0]=r,r},o={OK:0,LAST_BLOCK:-1,NOT_BZIP_DATA:-2,UNEXPECTED_INPUT_EOF:-3,UNEXPECTED_OUTPUT_EOF:-4,DATA_ERROR:-5,OUT_OF_MEMORY:-6,OBSOLETE_INPUT:-7,END_OF_BLOCK:-8},c={};c[o.LAST_BLOCK]="Bad file checksum",c[o.NOT_BZIP_DATA]="Not bzip data",c[o.UNEXPECTED_INPUT_EOF]="Unexpected input EOF",c[o.UNEXPECTED_OUTPUT_EOF]="Unexpected output EOF",c[o.DATA_ERROR]="Data error",c[o.OUT_OF_MEMORY]="Out of memory",c[o.OBSOLETE_INPUT]="Obsolete (pre 0.9.5) bzip format not supported.";const d=function(e,t){let r=c[e]||"unknown error";t&&(r+=": "+t);const n=new TypeError(r);throw n.errorCode=e,n};class l{constructor(e,t){this.writePos=this.writeCurrent=this.writeCount=0,this._start_bunzip(e,t);}_init_block(){return this._get_next_block()?(this.blockCRC=new a.default,!0):(this.writeCount=-1,!1)}_start_bunzip(e,t){const r=new Uint8Array(4);4===e.read(r,0,4)&&"BZh"===String.fromCharCode(r[0],r[1],r[2])||d(o.NOT_BZIP_DATA,"bad magic");const n=r[3]-48;(n<1||n>9)&&d(o.NOT_BZIP_DATA,"level out of range"),this.reader=new i.default(e),this.dbufSize=1e5*n,this.nextoutput=0,this.outputStream=t,this.streamCRC=0;}_get_next_block(){let e,t,r;const n=this.reader,i=n.pi();if("177245385090"===i)return !1;"314159265359"!==i&&d(o.NOT_BZIP_DATA),this.targetBlockCRC=n.read(32)>>>0,this.streamCRC=(this.targetBlockCRC^(this.streamCRC<<1|this.streamCRC>>>31))>>>0,n.read(1)&&d(o.OBSOLETE_INPUT);const a=n.read(24);a>this.dbufSize&&d(o.DATA_ERROR,"initial position out of bounds");let A=n.read(16),c=new Uint8Array(256),l=0;for(e=0;e<16;e++)if(A&1<<15-e){const i=16*e;for(r=n.read(16),t=0;t<16;t++)r&1<<15-t&&(c[l++]=i+t);}const f=n.read(3);(f<2||f>6)&&d(o.DATA_ERROR);const g=n.read(15);0===g&&d(o.DATA_ERROR);const h=new Uint8Array(256);for(e=0;e<f;e++)h[e]=e;const u=new Uint8Array(g);for(e=0;e<g;e++){for(t=0;n.read(1);t++)t>=f&&d(o.DATA_ERROR);u[e]=s(h,t);}let C,I=l+2,_=[];for(t=0;t<f;t++){const t=new Uint8Array(I),r=new Uint16Array(21);for(A=n.read(5),e=0;e<I;e++){for(;(A<1||A>20)&&d(o.DATA_ERROR),n.read(1);)n.read(1)?A--:A++;t[e]=A;}var m,B;for(m=B=t[0],e=1;e<I;e++)t[e]>B?B=t[e]:t[e]<m&&(m=t[e]);C={},_.push(C),C.permute=new Uint16Array(258),C.limit=new Uint32Array(22),C.base=new Uint32Array(21),C.minLen=m,C.maxLen=B;let i=0;for(e=m;e<=B;e++)for(r[e]=C.limit[e]=0,A=0;A<I;A++)t[A]===e&&(C.permute[i++]=A);for(e=0;e<I;e++)r[t[e]]++;for(i=A=0,e=m;e<B;e++)i+=r[e],C.limit[e]=i-1,i<<=1,A+=r[e],C.base[e+1]=i-A;C.limit[B+1]=Number.MAX_VALUE,C.limit[B]=i+r[B]-1,C.base[m]=0;}const p=new Uint32Array(256);for(e=0;e<256;e++)h[e]=e;let w,E=0,Q=0,y=0;const b=this.dbuf=new Uint32Array(this.dbufSize);for(I=0;;){for(I--||(I=49,y>=g&&d(o.DATA_ERROR),C=_[u[y++]]),e=C.minLen,t=n.read(e);e>C.maxLen&&d(o.DATA_ERROR),!(t<=C.limit[e]);e++)t=t<<1|n.read(1);t-=C.base[e],(t<0||t>=258)&&d(o.DATA_ERROR);const r=C.permute[t];if(0!==r&&1!==r){if(E)for(E=0,Q+A>this.dbufSize&&d(o.DATA_ERROR),w=c[h[0]],p[w]+=A;A--;)b[Q++]=w;if(r>l)break;Q>=this.dbufSize&&d(o.DATA_ERROR),e=r-1,w=s(h,e),w=c[w],p[w]++,b[Q++]=w;}else E||(E=1,A=0),A+=0===r?E:2*E,E<<=1;}for((a<0||a>=Q)&&d(o.DATA_ERROR),t=0,e=0;e<256;e++)r=t+p[e],p[e]=t,t=r;for(e=0;e<Q;e++)w=255&b[e],b[p[w]]|=e<<8,p[w]++;let S=0,D=0,k=0;return Q&&(S=b[a],D=255&S,S>>=8,k=-1),this.writePos=S,this.writeCurrent=D,this.writeCount=Q,this.writeRun=k,!0}_read_bunzip(e,t){let r,n,i;if(this.writeCount<0)return 0;let a=this.dbuf,A=this.writePos,s=this.writeCurrent,c=this.writeCount,l=(this.outputsize,this.writeRun);for(;c;){for(c--,n=s,A=a[A],s=255&A,A>>=8,3==l++?(r=s,i=n,s=-1):(r=1,i=s),this.blockCRC.updateCRCRun(i,r);r--;)this.outputStream.writeByte(i),this.nextoutput++;s!=n&&(l=0);}return this.writeCount=c,this.blockCRC.getCRC()!==this.targetBlockCRC&&d(o.DATA_ERROR,"Bad block CRC (got "+this.blockCRC.getCRC().toString(16)+" expected "+this.targetBlockCRC.toString(16)+")"),this.nextoutput}}const f=function(e){if("readByte"in e)return e;const t=new A.default;return t.pos=0,t.readByte=function(){return e[this.pos++]},t.seek=function(e){this.pos=e;},t.eof=function(){return this.pos>=e.length},t},g=function(e){const t=new A.default;let r=!0;if(e)if("number"==typeof e)t.buffer=new Uint8Array(e),r=!1;else {if("writeByte"in e)return e;t.buffer=e,r=!1;}else t.buffer=new Uint8Array(16384);return t.pos=0,t.writeByte=function(e){if(r&&this.pos>=this.buffer.length){const e=new Uint8Array(2*this.buffer.length);e.set(this.buffer),this.buffer=e;}this.buffer[this.pos++]=e;},t.getBuffer=function(){if(this.pos!==this.buffer.length){if(!r)throw new TypeError("outputsize does not match decoded input");const e=new Uint8Array(this.pos);e.set(this.buffer.slice(0,this.pos)),this.buffer=e;}return this.buffer},t._coerced=!0,t};t.default=l;},4271:e=>{const t=function(){};t.prototype.readByte=function(){throw new Error("abstract method readByte() not implemented")},t.prototype.read=function(e,t,r){let n=0;for(;n<r;){const r=this.readByte();if(r<0)return 0===n?-1:n;e[t++]=r,n++;}return n},t.prototype.seek=function(e){throw new Error("abstract method seek() not implemented")},t.prototype.writeByte=function(e){throw new Error("abstract method readByte() not implemented")},t.prototype.write=function(e,t,r){let n;for(n=0;n<r;n++)this.writeByte(e[t++]);return r},t.prototype.flush=function(){},e.exports=t;},6305:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.toHex=function(e){let t="";for(let r=0,i=e.length;r<i;r++)t+=n[e[r]];return t};const r=["0","1","2","3","4","5","6","7","8","9","A","B","C","D","E","F"],n=new Array(256);for(let e=0;e<256;e++)n[e]=`${r[e>>>4&15]}${r[15&e]}`;},8876:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.unzip=function(e){return (0, n.inflate)(e)};const n=r(1668);},3472:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.concatUint8Array=function(e){const t=new Uint8Array(function(e){let t=0;for(const r of e)t+=r.length;return t}(e));let r=0;for(const n of e)t.set(n,r),r+=n.length;return t};},2151:e=>{var t={utf8:{stringToBytes:function(e){return t.bin.stringToBytes(unescape(encodeURIComponent(e)))},bytesToString:function(e){return decodeURIComponent(escape(t.bin.bytesToString(e)))}},bin:{stringToBytes:function(e){for(var t=[],r=0;r<e.length;r++)t.push(255&e.charCodeAt(r));return t},bytesToString:function(e){for(var t=[],r=0;r<e.length;r++)t.push(String.fromCharCode(e[r]));return t.join("")}}};e.exports=t;},3939:e=>{var t,r;t="ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/",r={rotl:function(e,t){return e<<t|e>>>32-t},rotr:function(e,t){return e<<32-t|e>>>t},endian:function(e){if(e.constructor==Number)return 16711935&r.rotl(e,8)|4278255360&r.rotl(e,24);for(var t=0;t<e.length;t++)e[t]=r.endian(e[t]);return e},randomBytes:function(e){for(var t=[];e>0;e--)t.push(Math.floor(256*Math.random()));return t},bytesToWords:function(e){for(var t=[],r=0,n=0;r<e.length;r++,n+=8)t[n>>>5]|=e[r]<<24-n%32;return t},wordsToBytes:function(e){for(var t=[],r=0;r<32*e.length;r+=8)t.push(e[r>>>5]>>>24-r%32&255);return t},bytesToHex:function(e){for(var t=[],r=0;r<e.length;r++)t.push((e[r]>>>4).toString(16)),t.push((15&e[r]).toString(16));return t.join("")},hexToBytes:function(e){for(var t=[],r=0;r<e.length;r+=2)t.push(parseInt(e.substr(r,2),16));return t},bytesToBase64:function(e){for(var r=[],n=0;n<e.length;n+=3)for(var i=e[n]<<16|e[n+1]<<8|e[n+2],a=0;a<4;a++)8*n+6*a<=8*e.length?r.push(t.charAt(i>>>6*(3-a)&63)):r.push("=");return r.join("")},base64ToBytes:function(e){e=e.replace(/[^A-Z0-9+\/]/gi,"");for(var r=[],n=0,i=0;n<e.length;i=++n%4)0!=i&&r.push((t.indexOf(e.charAt(n-1))&Math.pow(2,-2*i+8)-1)<<2*i|t.indexOf(e.charAt(n))>>>6-2*i);return r}},e.exports=r;},689:(e,t,r)=>{r.r(t),r.d(t,{BlobFile:()=>s,LocalFile:()=>i(),RemoteFile:()=>A,fromUrl:()=>o,open:()=>c});var n=r(7937),i=r.n(n);function a(e){return ("object"==typeof e&&null!==e&&"message"in e?e.message:`${e}`).replace(/\.$/,"")}class A{constructor(e,t={}){this.baseOverrides={},this.url=e;const r=t.fetch||globalThis.fetch.bind(globalThis);t.overrides&&(this.baseOverrides=t.overrides),this.fetchImplementation=r;}async fetch(e,t){let r;try{r=await this.fetchImplementation(e,t);}catch(n){if(!`${n}`.includes("Failed to fetch"))throw new Error(`${a(n)} fetching ${e}`,{cause:n});console.warn(`generic-filehandle: refetching ${e} to attempt to work around chrome CORS header caching bug`);try{r=await this.fetchImplementation(e,{...t,cache:"reload"});}catch(t){throw new Error(`${a(t)} fetching ${e}`,{cause:t})}}return r}async read(e,t,r={}){const{headers:n={},signal:i,overrides:a={}}=r;e<1/0?n.range=`bytes=${t}-${t+e}`:e===1/0&&0!==t&&(n.range=`bytes=${t}-`);const A=await this.fetch(this.url,{...this.baseOverrides,...a,headers:{...n,...a.headers,...this.baseOverrides.headers},method:"GET",redirect:"follow",mode:"cors",signal:i});if(!A.ok)throw new Error(`HTTP ${A.status} fetching ${this.url}`);if(200===A.status&&0===t||206===A.status){const t=await A.arrayBuffer(),r=A.headers.get("content-range"),n=/\/(\d+)$/.exec(r||"");return n?.[1]&&(this._stat={size:parseInt(n[1],10)}),new Uint8Array(t.slice(0,e))}throw 200===A.status?new Error(`${this.url} fetch returned status 200, expected 206`):new Error(`HTTP ${A.status} fetching ${this.url}`)}async readFile(e={}){let t,r;"string"==typeof e?(t=e,r={}):(t=e.encoding,r=e,delete r.encoding);const{headers:n={},signal:i,overrides:a={}}=r,A=await this.fetch(this.url,{headers:n,method:"GET",redirect:"follow",mode:"cors",signal:i,...this.baseOverrides,...a});if(200!==A.status)throw new Error(`HTTP ${A.status} fetching ${this.url}`);if("utf8"===t)return A.text();if(t)throw new Error(`unsupported encoding: ${t}`);return new Uint8Array(await A.arrayBuffer())}async stat(){if(!this._stat&&(await this.read(10,0),!this._stat))throw new Error(`unable to determine size of file at ${this.url}`);return this._stat}async close(){}}class s{constructor(e){this.blob=e,this.size=e.size;}async read(e,t=0){if(!e)return new Uint8Array(0);const r=t,n=r+e;return new Uint8Array(await this.blob.slice(r,n).arrayBuffer())}async readFile(e){const t="string"==typeof e?e:e?.encoding;if("utf8"===t)return this.blob.text();if(t)throw new Error(`unsupported encoding: ${t}`);return new Uint8Array(await this.blob.arrayBuffer())}async stat(){return {size:this.size}}async close(){}}function o(e,t={}){return new A(e,t)}function c(e,t,r,n={}){if(void 0!==r)return r;if(void 0!==e)return o(e,n);if(void 0!==t)return new(i())(t,n);throw new Error("no url, path, or filehandle provided, cannot open")}},3503:(e,t,r)=>{var n,i,a,A,s;n=r(3939),i=r(2151).utf8,a=r(652),A=r(2151).bin,(s=function(e,t){e.constructor==String?e=t&&"binary"===t.encoding?A.stringToBytes(e):i.stringToBytes(e):a(e)?e=Array.prototype.slice.call(e,0):Array.isArray(e)||e.constructor===Uint8Array||(e=e.toString());for(var r=n.bytesToWords(e),o=8*e.length,c=1732584193,d=-271733879,l=-1732584194,f=271733878,g=0;g<r.length;g++)r[g]=16711935&(r[g]<<8|r[g]>>>24)|4278255360&(r[g]<<24|r[g]>>>8);r[o>>>5]|=128<<o%32,r[14+(o+64>>>9<<4)]=o;var h=s._ff,u=s._gg,C=s._hh,I=s._ii;for(g=0;g<r.length;g+=16){var _=c,m=d,B=l,p=f;c=h(c,d,l,f,r[g+0],7,-680876936),f=h(f,c,d,l,r[g+1],12,-389564586),l=h(l,f,c,d,r[g+2],17,606105819),d=h(d,l,f,c,r[g+3],22,-1044525330),c=h(c,d,l,f,r[g+4],7,-176418897),f=h(f,c,d,l,r[g+5],12,1200080426),l=h(l,f,c,d,r[g+6],17,-1473231341),d=h(d,l,f,c,r[g+7],22,-45705983),c=h(c,d,l,f,r[g+8],7,1770035416),f=h(f,c,d,l,r[g+9],12,-1958414417),l=h(l,f,c,d,r[g+10],17,-42063),d=h(d,l,f,c,r[g+11],22,-1990404162),c=h(c,d,l,f,r[g+12],7,1804603682),f=h(f,c,d,l,r[g+13],12,-40341101),l=h(l,f,c,d,r[g+14],17,-1502002290),c=u(c,d=h(d,l,f,c,r[g+15],22,1236535329),l,f,r[g+1],5,-165796510),f=u(f,c,d,l,r[g+6],9,-1069501632),l=u(l,f,c,d,r[g+11],14,643717713),d=u(d,l,f,c,r[g+0],20,-373897302),c=u(c,d,l,f,r[g+5],5,-701558691),f=u(f,c,d,l,r[g+10],9,38016083),l=u(l,f,c,d,r[g+15],14,-660478335),d=u(d,l,f,c,r[g+4],20,-405537848),c=u(c,d,l,f,r[g+9],5,568446438),f=u(f,c,d,l,r[g+14],9,-1019803690),l=u(l,f,c,d,r[g+3],14,-187363961),d=u(d,l,f,c,r[g+8],20,1163531501),c=u(c,d,l,f,r[g+13],5,-1444681467),f=u(f,c,d,l,r[g+2],9,-51403784),l=u(l,f,c,d,r[g+7],14,1735328473),c=C(c,d=u(d,l,f,c,r[g+12],20,-1926607734),l,f,r[g+5],4,-378558),f=C(f,c,d,l,r[g+8],11,-2022574463),l=C(l,f,c,d,r[g+11],16,1839030562),d=C(d,l,f,c,r[g+14],23,-35309556),c=C(c,d,l,f,r[g+1],4,-1530992060),f=C(f,c,d,l,r[g+4],11,1272893353),l=C(l,f,c,d,r[g+7],16,-155497632),d=C(d,l,f,c,r[g+10],23,-1094730640),c=C(c,d,l,f,r[g+13],4,681279174),f=C(f,c,d,l,r[g+0],11,-358537222),l=C(l,f,c,d,r[g+3],16,-722521979),d=C(d,l,f,c,r[g+6],23,76029189),c=C(c,d,l,f,r[g+9],4,-640364487),f=C(f,c,d,l,r[g+12],11,-421815835),l=C(l,f,c,d,r[g+15],16,530742520),c=I(c,d=C(d,l,f,c,r[g+2],23,-995338651),l,f,r[g+0],6,-198630844),f=I(f,c,d,l,r[g+7],10,1126891415),l=I(l,f,c,d,r[g+14],15,-1416354905),d=I(d,l,f,c,r[g+5],21,-57434055),c=I(c,d,l,f,r[g+12],6,1700485571),f=I(f,c,d,l,r[g+3],10,-1894986606),l=I(l,f,c,d,r[g+10],15,-1051523),d=I(d,l,f,c,r[g+1],21,-2054922799),c=I(c,d,l,f,r[g+8],6,1873313359),f=I(f,c,d,l,r[g+15],10,-30611744),l=I(l,f,c,d,r[g+6],15,-1560198380),d=I(d,l,f,c,r[g+13],21,1309151649),c=I(c,d,l,f,r[g+4],6,-145523070),f=I(f,c,d,l,r[g+11],10,-1120210379),l=I(l,f,c,d,r[g+2],15,718787259),d=I(d,l,f,c,r[g+9],21,-343485551),c=c+_>>>0,d=d+m>>>0,l=l+B>>>0,f=f+p>>>0;}return n.endian([c,d,l,f])})._ff=function(e,t,r,n,i,a,A){var s=e+(t&r|~t&n)+(i>>>0)+A;return (s<<a|s>>>32-a)+t},s._gg=function(e,t,r,n,i,a,A){var s=e+(t&n|r&~n)+(i>>>0)+A;return (s<<a|s>>>32-a)+t},s._hh=function(e,t,r,n,i,a,A){var s=e+(t^r^n)+(i>>>0)+A;return (s<<a|s>>>32-a)+t},s._ii=function(e,t,r,n,i,a,A){var s=e+(r^(t|~n))+(i>>>0)+A;return (s<<a|s>>>32-a)+t},s._blocksize=16,s._digestsize=16,e.exports=function(e,t){if(null==e)throw new Error("Illegal argument "+e);var r=n.wordsToBytes(s(e,t));return t&&t.asBytes?r:t&&t.asString?A.bytesToString(r):n.bytesToHex(r)};},652:e=>{function t(e){return !!e.constructor&&"function"==typeof e.constructor.isBuffer&&e.constructor.isBuffer(e)}e.exports=function(e){return null!=e&&(t(e)||function(e){return "function"==typeof e.readFloatLE&&"function"==typeof e.slice&&t(e.slice(0,0))}(e)||!!e._isBuffer)};},1668:(e,t,r)=>{var n={};(0, r(9805).assign)(n,r(3303),r(7083),r(9681)),e.exports=n;},3303:(e,t,r)=>{var n=r(8411),i=r(9805),a=r(1996),A=r(4674),s=r(4442),o=Object.prototype.toString;function c(e){if(!(this instanceof c))return new c(e);this.options=i.assign({level:-1,method:8,chunkSize:16384,windowBits:15,memLevel:8,strategy:0,to:""},e||{});var t=this.options;t.raw&&t.windowBits>0?t.windowBits=-t.windowBits:t.gzip&&t.windowBits>0&&t.windowBits<16&&(t.windowBits+=16),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new s,this.strm.avail_out=0;var r=n.deflateInit2(this.strm,t.level,t.method,t.windowBits,t.memLevel,t.strategy);if(0!==r)throw new Error(A[r]);if(t.header&&n.deflateSetHeader(this.strm,t.header),t.dictionary){var d;if(d="string"==typeof t.dictionary?a.string2buf(t.dictionary):"[object ArrayBuffer]"===o.call(t.dictionary)?new Uint8Array(t.dictionary):t.dictionary,0!==(r=n.deflateSetDictionary(this.strm,d)))throw new Error(A[r]);this._dict_set=!0;}}function d(e,t){var r=new c(t);if(r.push(e,!0),r.err)throw r.msg||A[r.err];return r.result}c.prototype.push=function(e,t){var r,A,s=this.strm,c=this.options.chunkSize;if(this.ended)return !1;A=t===~~t?t:!0===t?4:0,"string"==typeof e?s.input=a.string2buf(e):"[object ArrayBuffer]"===o.call(e)?s.input=new Uint8Array(e):s.input=e,s.next_in=0,s.avail_in=s.input.length;do{if(0===s.avail_out&&(s.output=new i.Buf8(c),s.next_out=0,s.avail_out=c),1!==(r=n.deflate(s,A))&&0!==r)return this.onEnd(r),this.ended=!0,!1;0!==s.avail_out&&(0!==s.avail_in||4!==A&&2!==A)||("string"===this.options.to?this.onData(a.buf2binstring(i.shrinkBuf(s.output,s.next_out))):this.onData(i.shrinkBuf(s.output,s.next_out)));}while((s.avail_in>0||0===s.avail_out)&&1!==r);return 4===A?(r=n.deflateEnd(this.strm),this.onEnd(r),this.ended=!0,0===r):2!==A||(this.onEnd(0),s.avail_out=0,!0)},c.prototype.onData=function(e){this.chunks.push(e);},c.prototype.onEnd=function(e){0===e&&("string"===this.options.to?this.result=this.chunks.join(""):this.result=i.flattenChunks(this.chunks)),this.chunks=[],this.err=e,this.msg=this.strm.msg;},t.Deflate=c,t.deflate=d,t.deflateRaw=function(e,t){return (t=t||{}).raw=!0,d(e,t)},t.gzip=function(e,t){return (t=t||{}).gzip=!0,d(e,t)};},7083:(e,t,r)=>{var n=r(1447),i=r(9805),a=r(1996),A=r(9681),s=r(4674),o=r(4442),c=r(7414),d=Object.prototype.toString;function l(e){if(!(this instanceof l))return new l(e);this.options=i.assign({chunkSize:16384,windowBits:0,to:""},e||{});var t=this.options;t.raw&&t.windowBits>=0&&t.windowBits<16&&(t.windowBits=-t.windowBits,0===t.windowBits&&(t.windowBits=-15)),!(t.windowBits>=0&&t.windowBits<16)||e&&e.windowBits||(t.windowBits+=32),t.windowBits>15&&t.windowBits<48&&(15&t.windowBits||(t.windowBits|=15)),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new o,this.strm.avail_out=0;var r=n.inflateInit2(this.strm,t.windowBits);if(r!==A.Z_OK)throw new Error(s[r]);if(this.header=new c,n.inflateGetHeader(this.strm,this.header),t.dictionary&&("string"==typeof t.dictionary?t.dictionary=a.string2buf(t.dictionary):"[object ArrayBuffer]"===d.call(t.dictionary)&&(t.dictionary=new Uint8Array(t.dictionary)),t.raw&&(r=n.inflateSetDictionary(this.strm,t.dictionary))!==A.Z_OK))throw new Error(s[r])}function f(e,t){var r=new l(t);if(r.push(e,!0),r.err)throw r.msg||s[r.err];return r.result}l.prototype.push=function(e,t){var r,s,o,c,l,f=this.strm,g=this.options.chunkSize,h=this.options.dictionary,u=!1;if(this.ended)return !1;s=t===~~t?t:!0===t?A.Z_FINISH:A.Z_NO_FLUSH,"string"==typeof e?f.input=a.binstring2buf(e):"[object ArrayBuffer]"===d.call(e)?f.input=new Uint8Array(e):f.input=e,f.next_in=0,f.avail_in=f.input.length;do{if(0===f.avail_out&&(f.output=new i.Buf8(g),f.next_out=0,f.avail_out=g),(r=n.inflate(f,A.Z_NO_FLUSH))===A.Z_NEED_DICT&&h&&(r=n.inflateSetDictionary(this.strm,h)),r===A.Z_BUF_ERROR&&!0===u&&(r=A.Z_OK,u=!1),r!==A.Z_STREAM_END&&r!==A.Z_OK)return this.onEnd(r),this.ended=!0,!1;f.next_out&&(0!==f.avail_out&&r!==A.Z_STREAM_END&&(0!==f.avail_in||s!==A.Z_FINISH&&s!==A.Z_SYNC_FLUSH)||("string"===this.options.to?(o=a.utf8border(f.output,f.next_out),c=f.next_out-o,l=a.buf2string(f.output,o),f.next_out=c,f.avail_out=g-c,c&&i.arraySet(f.output,f.output,o,c,0),this.onData(l)):this.onData(i.shrinkBuf(f.output,f.next_out)))),0===f.avail_in&&0===f.avail_out&&(u=!0);}while((f.avail_in>0||0===f.avail_out)&&r!==A.Z_STREAM_END);return r===A.Z_STREAM_END&&(s=A.Z_FINISH),s===A.Z_FINISH?(r=n.inflateEnd(this.strm),this.onEnd(r),this.ended=!0,r===A.Z_OK):s!==A.Z_SYNC_FLUSH||(this.onEnd(A.Z_OK),f.avail_out=0,!0)},l.prototype.onData=function(e){this.chunks.push(e);},l.prototype.onEnd=function(e){e===A.Z_OK&&("string"===this.options.to?this.result=this.chunks.join(""):this.result=i.flattenChunks(this.chunks)),this.chunks=[],this.err=e,this.msg=this.strm.msg;},t.Inflate=l,t.inflate=f,t.inflateRaw=function(e,t){return (t=t||{}).raw=!0,f(e,t)},t.ungzip=f;},9805:(e,t)=>{var r="undefined"!=typeof Uint8Array&&"undefined"!=typeof Uint16Array&&"undefined"!=typeof Int32Array;function n(e,t){return Object.prototype.hasOwnProperty.call(e,t)}t.assign=function(e){for(var t=Array.prototype.slice.call(arguments,1);t.length;){var r=t.shift();if(r){if("object"!=typeof r)throw new TypeError(r+"must be non-object");for(var i in r)n(r,i)&&(e[i]=r[i]);}}return e},t.shrinkBuf=function(e,t){return e.length===t?e:e.subarray?e.subarray(0,t):(e.length=t,e)};var i={arraySet:function(e,t,r,n,i){if(t.subarray&&e.subarray)e.set(t.subarray(r,r+n),i);else for(var a=0;a<n;a++)e[i+a]=t[r+a];},flattenChunks:function(e){var t,r,n,i,a,A;for(n=0,t=0,r=e.length;t<r;t++)n+=e[t].length;for(A=new Uint8Array(n),i=0,t=0,r=e.length;t<r;t++)a=e[t],A.set(a,i),i+=a.length;return A}},a={arraySet:function(e,t,r,n,i){for(var a=0;a<n;a++)e[i+a]=t[r+a];},flattenChunks:function(e){return [].concat.apply([],e)}};t.setTyped=function(e){e?(t.Buf8=Uint8Array,t.Buf16=Uint16Array,t.Buf32=Int32Array,t.assign(t,i)):(t.Buf8=Array,t.Buf16=Array,t.Buf32=Array,t.assign(t,a));},t.setTyped(r);},1996:(e,t,r)=>{var n=r(9805),i=!0,a=!0;try{String.fromCharCode.apply(null,[0]);}catch(e){i=!1;}try{String.fromCharCode.apply(null,new Uint8Array(1));}catch(e){a=!1;}for(var A=new n.Buf8(256),s=0;s<256;s++)A[s]=s>=252?6:s>=248?5:s>=240?4:s>=224?3:s>=192?2:1;function o(e,t){if(t<65534&&(e.subarray&&a||!e.subarray&&i))return String.fromCharCode.apply(null,n.shrinkBuf(e,t));for(var r="",A=0;A<t;A++)r+=String.fromCharCode(e[A]);return r}A[254]=A[254]=1,t.string2buf=function(e){var t,r,i,a,A,s=e.length,o=0;for(a=0;a<s;a++)55296==(64512&(r=e.charCodeAt(a)))&&a+1<s&&56320==(64512&(i=e.charCodeAt(a+1)))&&(r=65536+(r-55296<<10)+(i-56320),a++),o+=r<128?1:r<2048?2:r<65536?3:4;for(t=new n.Buf8(o),A=0,a=0;A<o;a++)55296==(64512&(r=e.charCodeAt(a)))&&a+1<s&&56320==(64512&(i=e.charCodeAt(a+1)))&&(r=65536+(r-55296<<10)+(i-56320),a++),r<128?t[A++]=r:r<2048?(t[A++]=192|r>>>6,t[A++]=128|63&r):r<65536?(t[A++]=224|r>>>12,t[A++]=128|r>>>6&63,t[A++]=128|63&r):(t[A++]=240|r>>>18,t[A++]=128|r>>>12&63,t[A++]=128|r>>>6&63,t[A++]=128|63&r);return t},t.buf2binstring=function(e){return o(e,e.length)},t.binstring2buf=function(e){for(var t=new n.Buf8(e.length),r=0,i=t.length;r<i;r++)t[r]=e.charCodeAt(r);return t},t.buf2string=function(e,t){var r,n,i,a,s=t||e.length,c=new Array(2*s);for(n=0,r=0;r<s;)if((i=e[r++])<128)c[n++]=i;else if((a=A[i])>4)c[n++]=65533,r+=a-1;else {for(i&=2===a?31:3===a?15:7;a>1&&r<s;)i=i<<6|63&e[r++],a--;a>1?c[n++]=65533:i<65536?c[n++]=i:(i-=65536,c[n++]=55296|i>>10&1023,c[n++]=56320|1023&i);}return o(c,n)},t.utf8border=function(e,t){var r;for((t=t||e.length)>e.length&&(t=e.length),r=t-1;r>=0&&128==(192&e[r]);)r--;return r<0||0===r?t:r+A[e[r]]>t?r:t};},3269:e=>{e.exports=function(e,t,r,n){for(var i=65535&e,a=e>>>16&65535,A=0;0!==r;){r-=A=r>2e3?2e3:r;do{a=a+(i=i+t[n++]|0)|0;}while(--A);i%=65521,a%=65521;}return i|a<<16};},9681:e=>{e.exports={Z_NO_FLUSH:0,Z_PARTIAL_FLUSH:1,Z_SYNC_FLUSH:2,Z_FULL_FLUSH:3,Z_FINISH:4,Z_BLOCK:5,Z_TREES:6,Z_OK:0,Z_STREAM_END:1,Z_NEED_DICT:2,Z_ERRNO:-1,Z_STREAM_ERROR:-2,Z_DATA_ERROR:-3,Z_BUF_ERROR:-5,Z_NO_COMPRESSION:0,Z_BEST_SPEED:1,Z_BEST_COMPRESSION:9,Z_DEFAULT_COMPRESSION:-1,Z_FILTERED:1,Z_HUFFMAN_ONLY:2,Z_RLE:3,Z_FIXED:4,Z_DEFAULT_STRATEGY:0,Z_BINARY:0,Z_TEXT:1,Z_UNKNOWN:2,Z_DEFLATED:8};},4823:e=>{var t=function(){for(var e,t=[],r=0;r<256;r++){e=r;for(var n=0;n<8;n++)e=1&e?3988292384^e>>>1:e>>>1;t[r]=e;}return t}();e.exports=function(e,r,n,i){var a=t,A=i+n;e^=-1;for(var s=i;s<A;s++)e=e>>>8^a[255&(e^r[s])];return ~e};},8411:(e,t,r)=>{var n,i=r(9805),a=r(3665),A=r(3269),s=r(4823),o=r(4674),c=-2,d=258,l=262,f=103,g=113,h=666;function u(e,t){return e.msg=o[t],t}function C(e){return (e<<1)-(e>4?9:0)}function I(e){for(var t=e.length;--t>=0;)e[t]=0;}function _(e){var t=e.state,r=t.pending;r>e.avail_out&&(r=e.avail_out),0!==r&&(i.arraySet(e.output,t.pending_buf,t.pending_out,r,e.next_out),e.next_out+=r,t.pending_out+=r,e.total_out+=r,e.avail_out-=r,t.pending-=r,0===t.pending&&(t.pending_out=0));}function m(e,t){a._tr_flush_block(e,e.block_start>=0?e.block_start:-1,e.strstart-e.block_start,t),e.block_start=e.strstart,_(e.strm);}function B(e,t){e.pending_buf[e.pending++]=t;}function p(e,t){e.pending_buf[e.pending++]=t>>>8&255,e.pending_buf[e.pending++]=255&t;}function w(e,t,r,n){var a=e.avail_in;return a>n&&(a=n),0===a?0:(e.avail_in-=a,i.arraySet(t,e.input,e.next_in,a,r),1===e.state.wrap?e.adler=A(e.adler,t,a,r):2===e.state.wrap&&(e.adler=s(e.adler,t,a,r)),e.next_in+=a,e.total_in+=a,a)}function E(e,t){var r,n,i=e.max_chain_length,a=e.strstart,A=e.prev_length,s=e.nice_match,o=e.strstart>e.w_size-l?e.strstart-(e.w_size-l):0,c=e.window,f=e.w_mask,g=e.prev,h=e.strstart+d,u=c[a+A-1],C=c[a+A];e.prev_length>=e.good_match&&(i>>=2),s>e.lookahead&&(s=e.lookahead);do{if(c[(r=t)+A]===C&&c[r+A-1]===u&&c[r]===c[a]&&c[++r]===c[a+1]){a+=2,r++;do{}while(c[++a]===c[++r]&&c[++a]===c[++r]&&c[++a]===c[++r]&&c[++a]===c[++r]&&c[++a]===c[++r]&&c[++a]===c[++r]&&c[++a]===c[++r]&&c[++a]===c[++r]&&a<h);if(n=d-(h-a),a=h-d,n>A){if(e.match_start=t,A=n,n>=s)break;u=c[a+A-1],C=c[a+A];}}}while((t=g[t&f])>o&&0!=--i);return A<=e.lookahead?A:e.lookahead}function Q(e){var t,r,n,a,A,s=e.w_size;do{if(a=e.window_size-e.lookahead-e.strstart,e.strstart>=s+(s-l)){i.arraySet(e.window,e.window,s,s,0),e.match_start-=s,e.strstart-=s,e.block_start-=s,t=r=e.hash_size;do{n=e.head[--t],e.head[t]=n>=s?n-s:0;}while(--r);t=r=s;do{n=e.prev[--t],e.prev[t]=n>=s?n-s:0;}while(--r);a+=s;}if(0===e.strm.avail_in)break;if(r=w(e.strm,e.window,e.strstart+e.lookahead,a),e.lookahead+=r,e.lookahead+e.insert>=3)for(A=e.strstart-e.insert,e.ins_h=e.window[A],e.ins_h=(e.ins_h<<e.hash_shift^e.window[A+1])&e.hash_mask;e.insert&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[A+3-1])&e.hash_mask,e.prev[A&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=A,A++,e.insert--,!(e.lookahead+e.insert<3)););}while(e.lookahead<l&&0!==e.strm.avail_in)}function y(e,t){for(var r,n;;){if(e.lookahead<l){if(Q(e),e.lookahead<l&&0===t)return 1;if(0===e.lookahead)break}if(r=0,e.lookahead>=3&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+3-1])&e.hash_mask,r=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart),0!==r&&e.strstart-r<=e.w_size-l&&(e.match_length=E(e,r)),e.match_length>=3)if(n=a._tr_tally(e,e.strstart-e.match_start,e.match_length-3),e.lookahead-=e.match_length,e.match_length<=e.max_lazy_match&&e.lookahead>=3){e.match_length--;do{e.strstart++,e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+3-1])&e.hash_mask,r=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart;}while(0!=--e.match_length);e.strstart++;}else e.strstart+=e.match_length,e.match_length=0,e.ins_h=e.window[e.strstart],e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+1])&e.hash_mask;else n=a._tr_tally(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++;if(n&&(m(e,!1),0===e.strm.avail_out))return 1}return e.insert=e.strstart<2?e.strstart:2,4===t?(m(e,!0),0===e.strm.avail_out?3:4):e.last_lit&&(m(e,!1),0===e.strm.avail_out)?1:2}function b(e,t){for(var r,n,i;;){if(e.lookahead<l){if(Q(e),e.lookahead<l&&0===t)return 1;if(0===e.lookahead)break}if(r=0,e.lookahead>=3&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+3-1])&e.hash_mask,r=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart),e.prev_length=e.match_length,e.prev_match=e.match_start,e.match_length=2,0!==r&&e.prev_length<e.max_lazy_match&&e.strstart-r<=e.w_size-l&&(e.match_length=E(e,r),e.match_length<=5&&(1===e.strategy||3===e.match_length&&e.strstart-e.match_start>4096)&&(e.match_length=2)),e.prev_length>=3&&e.match_length<=e.prev_length){i=e.strstart+e.lookahead-3,n=a._tr_tally(e,e.strstart-1-e.prev_match,e.prev_length-3),e.lookahead-=e.prev_length-1,e.prev_length-=2;do{++e.strstart<=i&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+3-1])&e.hash_mask,r=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart);}while(0!=--e.prev_length);if(e.match_available=0,e.match_length=2,e.strstart++,n&&(m(e,!1),0===e.strm.avail_out))return 1}else if(e.match_available){if((n=a._tr_tally(e,0,e.window[e.strstart-1]))&&m(e,!1),e.strstart++,e.lookahead--,0===e.strm.avail_out)return 1}else e.match_available=1,e.strstart++,e.lookahead--;}return e.match_available&&(n=a._tr_tally(e,0,e.window[e.strstart-1]),e.match_available=0),e.insert=e.strstart<2?e.strstart:2,4===t?(m(e,!0),0===e.strm.avail_out?3:4):e.last_lit&&(m(e,!1),0===e.strm.avail_out)?1:2}function S(e,t,r,n,i){this.good_length=e,this.max_lazy=t,this.nice_length=r,this.max_chain=n,this.func=i;}function D(){this.strm=null,this.status=0,this.pending_buf=null,this.pending_buf_size=0,this.pending_out=0,this.pending=0,this.wrap=0,this.gzhead=null,this.gzindex=0,this.method=8,this.last_flush=-1,this.w_size=0,this.w_bits=0,this.w_mask=0,this.window=null,this.window_size=0,this.prev=null,this.head=null,this.ins_h=0,this.hash_size=0,this.hash_bits=0,this.hash_mask=0,this.hash_shift=0,this.block_start=0,this.match_length=0,this.prev_match=0,this.match_available=0,this.strstart=0,this.match_start=0,this.lookahead=0,this.prev_length=0,this.max_chain_length=0,this.max_lazy_match=0,this.level=0,this.strategy=0,this.good_match=0,this.nice_match=0,this.dyn_ltree=new i.Buf16(1146),this.dyn_dtree=new i.Buf16(122),this.bl_tree=new i.Buf16(78),I(this.dyn_ltree),I(this.dyn_dtree),I(this.bl_tree),this.l_desc=null,this.d_desc=null,this.bl_desc=null,this.bl_count=new i.Buf16(16),this.heap=new i.Buf16(573),I(this.heap),this.heap_len=0,this.heap_max=0,this.depth=new i.Buf16(573),I(this.depth),this.l_buf=0,this.lit_bufsize=0,this.last_lit=0,this.d_buf=0,this.opt_len=0,this.static_len=0,this.matches=0,this.insert=0,this.bi_buf=0,this.bi_valid=0;}function k(e){var t;return e&&e.state?(e.total_in=e.total_out=0,e.data_type=2,(t=e.state).pending=0,t.pending_out=0,t.wrap<0&&(t.wrap=-t.wrap),t.status=t.wrap?42:g,e.adler=2===t.wrap?0:1,t.last_flush=0,a._tr_init(t),0):u(e,c)}function v(e){var t,r=k(e);return 0===r&&((t=e.state).window_size=2*t.w_size,I(t.head),t.max_lazy_match=n[t.level].max_lazy,t.good_match=n[t.level].good_length,t.nice_match=n[t.level].nice_length,t.max_chain_length=n[t.level].max_chain,t.strstart=0,t.block_start=0,t.lookahead=0,t.insert=0,t.match_length=t.prev_length=2,t.match_available=0,t.ins_h=0),r}function R(e,t,r,n,a,A){if(!e)return c;var s=1;if(-1===t&&(t=6),n<0?(s=0,n=-n):n>15&&(s=2,n-=16),a<1||a>9||8!==r||n<8||n>15||t<0||t>9||A<0||A>4)return u(e,c);8===n&&(n=9);var o=new D;return e.state=o,o.strm=e,o.wrap=s,o.gzhead=null,o.w_bits=n,o.w_size=1<<o.w_bits,o.w_mask=o.w_size-1,o.hash_bits=a+7,o.hash_size=1<<o.hash_bits,o.hash_mask=o.hash_size-1,o.hash_shift=~~((o.hash_bits+3-1)/3),o.window=new i.Buf8(2*o.w_size),o.head=new i.Buf16(o.hash_size),o.prev=new i.Buf16(o.w_size),o.lit_bufsize=1<<a+6,o.pending_buf_size=4*o.lit_bufsize,o.pending_buf=new i.Buf8(o.pending_buf_size),o.d_buf=1*o.lit_bufsize,o.l_buf=3*o.lit_bufsize,o.level=t,o.strategy=A,o.method=r,v(e)}n=[new S(0,0,0,0,(function(e,t){var r=65535;for(r>e.pending_buf_size-5&&(r=e.pending_buf_size-5);;){if(e.lookahead<=1){if(Q(e),0===e.lookahead&&0===t)return 1;if(0===e.lookahead)break}e.strstart+=e.lookahead,e.lookahead=0;var n=e.block_start+r;if((0===e.strstart||e.strstart>=n)&&(e.lookahead=e.strstart-n,e.strstart=n,m(e,!1),0===e.strm.avail_out))return 1;if(e.strstart-e.block_start>=e.w_size-l&&(m(e,!1),0===e.strm.avail_out))return 1}return e.insert=0,4===t?(m(e,!0),0===e.strm.avail_out?3:4):(e.strstart>e.block_start&&(m(e,!1),e.strm.avail_out),1)})),new S(4,4,8,4,y),new S(4,5,16,8,y),new S(4,6,32,32,y),new S(4,4,16,16,b),new S(8,16,32,32,b),new S(8,16,128,128,b),new S(8,32,128,256,b),new S(32,128,258,1024,b),new S(32,258,258,4096,b)],t.deflateInit=function(e,t){return R(e,t,8,15,8,0)},t.deflateInit2=R,t.deflateReset=v,t.deflateResetKeep=k,t.deflateSetHeader=function(e,t){return e&&e.state?2!==e.state.wrap?c:(e.state.gzhead=t,0):c},t.deflate=function(e,t){var r,i,A,o;if(!e||!e.state||t>5||t<0)return e?u(e,c):c;if(i=e.state,!e.output||!e.input&&0!==e.avail_in||i.status===h&&4!==t)return u(e,0===e.avail_out?-5:c);if(i.strm=e,r=i.last_flush,i.last_flush=t,42===i.status)if(2===i.wrap)e.adler=0,B(i,31),B(i,139),B(i,8),i.gzhead?(B(i,(i.gzhead.text?1:0)+(i.gzhead.hcrc?2:0)+(i.gzhead.extra?4:0)+(i.gzhead.name?8:0)+(i.gzhead.comment?16:0)),B(i,255&i.gzhead.time),B(i,i.gzhead.time>>8&255),B(i,i.gzhead.time>>16&255),B(i,i.gzhead.time>>24&255),B(i,9===i.level?2:i.strategy>=2||i.level<2?4:0),B(i,255&i.gzhead.os),i.gzhead.extra&&i.gzhead.extra.length&&(B(i,255&i.gzhead.extra.length),B(i,i.gzhead.extra.length>>8&255)),i.gzhead.hcrc&&(e.adler=s(e.adler,i.pending_buf,i.pending,0)),i.gzindex=0,i.status=69):(B(i,0),B(i,0),B(i,0),B(i,0),B(i,0),B(i,9===i.level?2:i.strategy>=2||i.level<2?4:0),B(i,3),i.status=g);else {var l=8+(i.w_bits-8<<4)<<8;l|=(i.strategy>=2||i.level<2?0:i.level<6?1:6===i.level?2:3)<<6,0!==i.strstart&&(l|=32),l+=31-l%31,i.status=g,p(i,l),0!==i.strstart&&(p(i,e.adler>>>16),p(i,65535&e.adler)),e.adler=1;}if(69===i.status)if(i.gzhead.extra){for(A=i.pending;i.gzindex<(65535&i.gzhead.extra.length)&&(i.pending!==i.pending_buf_size||(i.gzhead.hcrc&&i.pending>A&&(e.adler=s(e.adler,i.pending_buf,i.pending-A,A)),_(e),A=i.pending,i.pending!==i.pending_buf_size));)B(i,255&i.gzhead.extra[i.gzindex]),i.gzindex++;i.gzhead.hcrc&&i.pending>A&&(e.adler=s(e.adler,i.pending_buf,i.pending-A,A)),i.gzindex===i.gzhead.extra.length&&(i.gzindex=0,i.status=73);}else i.status=73;if(73===i.status)if(i.gzhead.name){A=i.pending;do{if(i.pending===i.pending_buf_size&&(i.gzhead.hcrc&&i.pending>A&&(e.adler=s(e.adler,i.pending_buf,i.pending-A,A)),_(e),A=i.pending,i.pending===i.pending_buf_size)){o=1;break}o=i.gzindex<i.gzhead.name.length?255&i.gzhead.name.charCodeAt(i.gzindex++):0,B(i,o);}while(0!==o);i.gzhead.hcrc&&i.pending>A&&(e.adler=s(e.adler,i.pending_buf,i.pending-A,A)),0===o&&(i.gzindex=0,i.status=91);}else i.status=91;if(91===i.status)if(i.gzhead.comment){A=i.pending;do{if(i.pending===i.pending_buf_size&&(i.gzhead.hcrc&&i.pending>A&&(e.adler=s(e.adler,i.pending_buf,i.pending-A,A)),_(e),A=i.pending,i.pending===i.pending_buf_size)){o=1;break}o=i.gzindex<i.gzhead.comment.length?255&i.gzhead.comment.charCodeAt(i.gzindex++):0,B(i,o);}while(0!==o);i.gzhead.hcrc&&i.pending>A&&(e.adler=s(e.adler,i.pending_buf,i.pending-A,A)),0===o&&(i.status=f);}else i.status=f;if(i.status===f&&(i.gzhead.hcrc?(i.pending+2>i.pending_buf_size&&_(e),i.pending+2<=i.pending_buf_size&&(B(i,255&e.adler),B(i,e.adler>>8&255),e.adler=0,i.status=g)):i.status=g),0!==i.pending){if(_(e),0===e.avail_out)return i.last_flush=-1,0}else if(0===e.avail_in&&C(t)<=C(r)&&4!==t)return u(e,-5);if(i.status===h&&0!==e.avail_in)return u(e,-5);if(0!==e.avail_in||0!==i.lookahead||0!==t&&i.status!==h){var w=2===i.strategy?function(e,t){for(var r;;){if(0===e.lookahead&&(Q(e),0===e.lookahead)){if(0===t)return 1;break}if(e.match_length=0,r=a._tr_tally(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++,r&&(m(e,!1),0===e.strm.avail_out))return 1}return e.insert=0,4===t?(m(e,!0),0===e.strm.avail_out?3:4):e.last_lit&&(m(e,!1),0===e.strm.avail_out)?1:2}(i,t):3===i.strategy?function(e,t){for(var r,n,i,A,s=e.window;;){if(e.lookahead<=d){if(Q(e),e.lookahead<=d&&0===t)return 1;if(0===e.lookahead)break}if(e.match_length=0,e.lookahead>=3&&e.strstart>0&&(n=s[i=e.strstart-1])===s[++i]&&n===s[++i]&&n===s[++i]){A=e.strstart+d;do{}while(n===s[++i]&&n===s[++i]&&n===s[++i]&&n===s[++i]&&n===s[++i]&&n===s[++i]&&n===s[++i]&&n===s[++i]&&i<A);e.match_length=d-(A-i),e.match_length>e.lookahead&&(e.match_length=e.lookahead);}if(e.match_length>=3?(r=a._tr_tally(e,1,e.match_length-3),e.lookahead-=e.match_length,e.strstart+=e.match_length,e.match_length=0):(r=a._tr_tally(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++),r&&(m(e,!1),0===e.strm.avail_out))return 1}return e.insert=0,4===t?(m(e,!0),0===e.strm.avail_out?3:4):e.last_lit&&(m(e,!1),0===e.strm.avail_out)?1:2}(i,t):n[i.level].func(i,t);if(3!==w&&4!==w||(i.status=h),1===w||3===w)return 0===e.avail_out&&(i.last_flush=-1),0;if(2===w&&(1===t?a._tr_align(i):5!==t&&(a._tr_stored_block(i,0,0,!1),3===t&&(I(i.head),0===i.lookahead&&(i.strstart=0,i.block_start=0,i.insert=0))),_(e),0===e.avail_out))return i.last_flush=-1,0}return 4!==t?0:i.wrap<=0?1:(2===i.wrap?(B(i,255&e.adler),B(i,e.adler>>8&255),B(i,e.adler>>16&255),B(i,e.adler>>24&255),B(i,255&e.total_in),B(i,e.total_in>>8&255),B(i,e.total_in>>16&255),B(i,e.total_in>>24&255)):(p(i,e.adler>>>16),p(i,65535&e.adler)),_(e),i.wrap>0&&(i.wrap=-i.wrap),0!==i.pending?0:1)},t.deflateEnd=function(e){var t;return e&&e.state?42!==(t=e.state.status)&&69!==t&&73!==t&&91!==t&&t!==f&&t!==g&&t!==h?u(e,c):(e.state=null,t===g?u(e,-3):0):c},t.deflateSetDictionary=function(e,t){var r,n,a,s,o,d,l,f,g=t.length;if(!e||!e.state)return c;if(2===(s=(r=e.state).wrap)||1===s&&42!==r.status||r.lookahead)return c;for(1===s&&(e.adler=A(e.adler,t,g,0)),r.wrap=0,g>=r.w_size&&(0===s&&(I(r.head),r.strstart=0,r.block_start=0,r.insert=0),f=new i.Buf8(r.w_size),i.arraySet(f,t,g-r.w_size,r.w_size,0),t=f,g=r.w_size),o=e.avail_in,d=e.next_in,l=e.input,e.avail_in=g,e.next_in=0,e.input=t,Q(r);r.lookahead>=3;){n=r.strstart,a=r.lookahead-2;do{r.ins_h=(r.ins_h<<r.hash_shift^r.window[n+3-1])&r.hash_mask,r.prev[n&r.w_mask]=r.head[r.ins_h],r.head[r.ins_h]=n,n++;}while(--a);r.strstart=n,r.lookahead=2,Q(r);}return r.strstart+=r.lookahead,r.block_start=r.strstart,r.insert=r.lookahead,r.lookahead=0,r.match_length=r.prev_length=2,r.match_available=0,e.next_in=d,e.input=l,e.avail_in=o,r.wrap=s,0},t.deflateInfo="pako deflate (from Nodeca project)";},7414:e=>{e.exports=function(){this.text=0,this.time=0,this.xflags=0,this.os=0,this.extra=null,this.extra_len=0,this.name="",this.comment="",this.hcrc=0,this.done=!1;};},7293:e=>{e.exports=function(e,t){var r,n,i,a,A,s,o,c,d,l,f,g,h,u,C,I,_,m,B,p,w,E,Q,y,b;r=e.state,n=e.next_in,y=e.input,i=n+(e.avail_in-5),a=e.next_out,b=e.output,A=a-(t-e.avail_out),s=a+(e.avail_out-257),o=r.dmax,c=r.wsize,d=r.whave,l=r.wnext,f=r.window,g=r.hold,h=r.bits,u=r.lencode,C=r.distcode,I=(1<<r.lenbits)-1,_=(1<<r.distbits)-1;e:do{h<15&&(g+=y[n++]<<h,h+=8,g+=y[n++]<<h,h+=8),m=u[g&I];t:for(;;){if(g>>>=B=m>>>24,h-=B,0==(B=m>>>16&255))b[a++]=65535&m;else {if(!(16&B)){if(64&B){if(32&B){r.mode=12;break e}e.msg="invalid literal/length code",r.mode=30;break e}m=u[(65535&m)+(g&(1<<B)-1)];continue t}for(p=65535&m,(B&=15)&&(h<B&&(g+=y[n++]<<h,h+=8),p+=g&(1<<B)-1,g>>>=B,h-=B),h<15&&(g+=y[n++]<<h,h+=8,g+=y[n++]<<h,h+=8),m=C[g&_];;){if(g>>>=B=m>>>24,h-=B,16&(B=m>>>16&255)){if(w=65535&m,h<(B&=15)&&(g+=y[n++]<<h,(h+=8)<B&&(g+=y[n++]<<h,h+=8)),(w+=g&(1<<B)-1)>o){e.msg="invalid distance too far back",r.mode=30;break e}if(g>>>=B,h-=B,w>(B=a-A)){if((B=w-B)>d&&r.sane){e.msg="invalid distance too far back",r.mode=30;break e}if(E=0,Q=f,0===l){if(E+=c-B,B<p){p-=B;do{b[a++]=f[E++];}while(--B);E=a-w,Q=b;}}else if(l<B){if(E+=c+l-B,(B-=l)<p){p-=B;do{b[a++]=f[E++];}while(--B);if(E=0,l<p){p-=B=l;do{b[a++]=f[E++];}while(--B);E=a-w,Q=b;}}}else if(E+=l-B,B<p){p-=B;do{b[a++]=f[E++];}while(--B);E=a-w,Q=b;}for(;p>2;)b[a++]=Q[E++],b[a++]=Q[E++],b[a++]=Q[E++],p-=3;p&&(b[a++]=Q[E++],p>1&&(b[a++]=Q[E++]));}else {E=a-w;do{b[a++]=b[E++],b[a++]=b[E++],b[a++]=b[E++],p-=3;}while(p>2);p&&(b[a++]=b[E++],p>1&&(b[a++]=b[E++]));}break}if(64&B){e.msg="invalid distance code",r.mode=30;break e}m=C[(65535&m)+(g&(1<<B)-1)];}}break}}while(n<i&&a<s);n-=p=h>>3,g&=(1<<(h-=p<<3))-1,e.next_in=n,e.next_out=a,e.avail_in=n<i?i-n+5:5-(n-i),e.avail_out=a<s?s-a+257:257-(a-s),r.hold=g,r.bits=h;};},1447:(e,t,r)=>{var n=r(9805),i=r(3269),a=r(4823),A=r(7293),s=r(1998),o=-2,c=12,d=30;function l(e){return (e>>>24&255)+(e>>>8&65280)+((65280&e)<<8)+((255&e)<<24)}function f(){this.mode=0,this.last=!1,this.wrap=0,this.havedict=!1,this.flags=0,this.dmax=0,this.check=0,this.total=0,this.head=null,this.wbits=0,this.wsize=0,this.whave=0,this.wnext=0,this.window=null,this.hold=0,this.bits=0,this.length=0,this.offset=0,this.extra=0,this.lencode=null,this.distcode=null,this.lenbits=0,this.distbits=0,this.ncode=0,this.nlen=0,this.ndist=0,this.have=0,this.next=null,this.lens=new n.Buf16(320),this.work=new n.Buf16(288),this.lendyn=null,this.distdyn=null,this.sane=0,this.back=0,this.was=0;}function g(e){var t;return e&&e.state?(t=e.state,e.total_in=e.total_out=t.total=0,e.msg="",t.wrap&&(e.adler=1&t.wrap),t.mode=1,t.last=0,t.havedict=0,t.dmax=32768,t.head=null,t.hold=0,t.bits=0,t.lencode=t.lendyn=new n.Buf32(852),t.distcode=t.distdyn=new n.Buf32(592),t.sane=1,t.back=-1,0):o}function h(e){var t;return e&&e.state?((t=e.state).wsize=0,t.whave=0,t.wnext=0,g(e)):o}function u(e,t){var r,n;return e&&e.state?(n=e.state,t<0?(r=0,t=-t):(r=1+(t>>4),t<48&&(t&=15)),t&&(t<8||t>15)?o:(null!==n.window&&n.wbits!==t&&(n.window=null),n.wrap=r,n.wbits=t,h(e))):o}function C(e,t){var r,n;return e?(n=new f,e.state=n,n.window=null,0!==(r=u(e,t))&&(e.state=null),r):o}var I,_,m=!0;function B(e){if(m){var t;for(I=new n.Buf32(512),_=new n.Buf32(32),t=0;t<144;)e.lens[t++]=8;for(;t<256;)e.lens[t++]=9;for(;t<280;)e.lens[t++]=7;for(;t<288;)e.lens[t++]=8;for(s(1,e.lens,0,288,I,0,e.work,{bits:9}),t=0;t<32;)e.lens[t++]=5;s(2,e.lens,0,32,_,0,e.work,{bits:5}),m=!1;}e.lencode=I,e.lenbits=9,e.distcode=_,e.distbits=5;}function p(e,t,r,i){var a,A=e.state;return null===A.window&&(A.wsize=1<<A.wbits,A.wnext=0,A.whave=0,A.window=new n.Buf8(A.wsize)),i>=A.wsize?(n.arraySet(A.window,t,r-A.wsize,A.wsize,0),A.wnext=0,A.whave=A.wsize):((a=A.wsize-A.wnext)>i&&(a=i),n.arraySet(A.window,t,r-i,a,A.wnext),(i-=a)?(n.arraySet(A.window,t,r-i,i,0),A.wnext=i,A.whave=A.wsize):(A.wnext+=a,A.wnext===A.wsize&&(A.wnext=0),A.whave<A.wsize&&(A.whave+=a))),0}t.inflateReset=h,t.inflateReset2=u,t.inflateResetKeep=g,t.inflateInit=function(e){return C(e,15)},t.inflateInit2=C,t.inflate=function(e,t){var r,f,g,h,u,C,I,_,m,w,E,Q,y,b,S,D,k,v,R,F,N,M,x,L,O=0,T=new n.Buf8(4),q=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15];if(!e||!e.state||!e.output||!e.input&&0!==e.avail_in)return o;(r=e.state).mode===c&&(r.mode=13),u=e.next_out,g=e.output,I=e.avail_out,h=e.next_in,f=e.input,C=e.avail_in,_=r.hold,m=r.bits,w=C,E=I,M=0;e:for(;;)switch(r.mode){case 1:if(0===r.wrap){r.mode=13;break}for(;m<16;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}if(2&r.wrap&&35615===_){r.check=0,T[0]=255&_,T[1]=_>>>8&255,r.check=a(r.check,T,2,0),_=0,m=0,r.mode=2;break}if(r.flags=0,r.head&&(r.head.done=!1),!(1&r.wrap)||(((255&_)<<8)+(_>>8))%31){e.msg="incorrect header check",r.mode=d;break}if(8!=(15&_)){e.msg="unknown compression method",r.mode=d;break}if(m-=4,N=8+(15&(_>>>=4)),0===r.wbits)r.wbits=N;else if(N>r.wbits){e.msg="invalid window size",r.mode=d;break}r.dmax=1<<N,e.adler=r.check=1,r.mode=512&_?10:c,_=0,m=0;break;case 2:for(;m<16;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}if(r.flags=_,8!=(255&r.flags)){e.msg="unknown compression method",r.mode=d;break}if(57344&r.flags){e.msg="unknown header flags set",r.mode=d;break}r.head&&(r.head.text=_>>8&1),512&r.flags&&(T[0]=255&_,T[1]=_>>>8&255,r.check=a(r.check,T,2,0)),_=0,m=0,r.mode=3;case 3:for(;m<32;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}r.head&&(r.head.time=_),512&r.flags&&(T[0]=255&_,T[1]=_>>>8&255,T[2]=_>>>16&255,T[3]=_>>>24&255,r.check=a(r.check,T,4,0)),_=0,m=0,r.mode=4;case 4:for(;m<16;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}r.head&&(r.head.xflags=255&_,r.head.os=_>>8),512&r.flags&&(T[0]=255&_,T[1]=_>>>8&255,r.check=a(r.check,T,2,0)),_=0,m=0,r.mode=5;case 5:if(1024&r.flags){for(;m<16;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}r.length=_,r.head&&(r.head.extra_len=_),512&r.flags&&(T[0]=255&_,T[1]=_>>>8&255,r.check=a(r.check,T,2,0)),_=0,m=0;}else r.head&&(r.head.extra=null);r.mode=6;case 6:if(1024&r.flags&&((Q=r.length)>C&&(Q=C),Q&&(r.head&&(N=r.head.extra_len-r.length,r.head.extra||(r.head.extra=new Array(r.head.extra_len)),n.arraySet(r.head.extra,f,h,Q,N)),512&r.flags&&(r.check=a(r.check,f,Q,h)),C-=Q,h+=Q,r.length-=Q),r.length))break e;r.length=0,r.mode=7;case 7:if(2048&r.flags){if(0===C)break e;Q=0;do{N=f[h+Q++],r.head&&N&&r.length<65536&&(r.head.name+=String.fromCharCode(N));}while(N&&Q<C);if(512&r.flags&&(r.check=a(r.check,f,Q,h)),C-=Q,h+=Q,N)break e}else r.head&&(r.head.name=null);r.length=0,r.mode=8;case 8:if(4096&r.flags){if(0===C)break e;Q=0;do{N=f[h+Q++],r.head&&N&&r.length<65536&&(r.head.comment+=String.fromCharCode(N));}while(N&&Q<C);if(512&r.flags&&(r.check=a(r.check,f,Q,h)),C-=Q,h+=Q,N)break e}else r.head&&(r.head.comment=null);r.mode=9;case 9:if(512&r.flags){for(;m<16;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}if(_!==(65535&r.check)){e.msg="header crc mismatch",r.mode=d;break}_=0,m=0;}r.head&&(r.head.hcrc=r.flags>>9&1,r.head.done=!0),e.adler=r.check=0,r.mode=c;break;case 10:for(;m<32;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}e.adler=r.check=l(_),_=0,m=0,r.mode=11;case 11:if(0===r.havedict)return e.next_out=u,e.avail_out=I,e.next_in=h,e.avail_in=C,r.hold=_,r.bits=m,2;e.adler=r.check=1,r.mode=c;case c:if(5===t||6===t)break e;case 13:if(r.last){_>>>=7&m,m-=7&m,r.mode=27;break}for(;m<3;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}switch(r.last=1&_,m-=1,3&(_>>>=1)){case 0:r.mode=14;break;case 1:if(B(r),r.mode=20,6===t){_>>>=2,m-=2;break e}break;case 2:r.mode=17;break;case 3:e.msg="invalid block type",r.mode=d;}_>>>=2,m-=2;break;case 14:for(_>>>=7&m,m-=7&m;m<32;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}if((65535&_)!=(_>>>16^65535)){e.msg="invalid stored block lengths",r.mode=d;break}if(r.length=65535&_,_=0,m=0,r.mode=15,6===t)break e;case 15:r.mode=16;case 16:if(Q=r.length){if(Q>C&&(Q=C),Q>I&&(Q=I),0===Q)break e;n.arraySet(g,f,h,Q,u),C-=Q,h+=Q,I-=Q,u+=Q,r.length-=Q;break}r.mode=c;break;case 17:for(;m<14;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}if(r.nlen=257+(31&_),_>>>=5,m-=5,r.ndist=1+(31&_),_>>>=5,m-=5,r.ncode=4+(15&_),_>>>=4,m-=4,r.nlen>286||r.ndist>30){e.msg="too many length or distance symbols",r.mode=d;break}r.have=0,r.mode=18;case 18:for(;r.have<r.ncode;){for(;m<3;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}r.lens[q[r.have++]]=7&_,_>>>=3,m-=3;}for(;r.have<19;)r.lens[q[r.have++]]=0;if(r.lencode=r.lendyn,r.lenbits=7,x={bits:r.lenbits},M=s(0,r.lens,0,19,r.lencode,0,r.work,x),r.lenbits=x.bits,M){e.msg="invalid code lengths set",r.mode=d;break}r.have=0,r.mode=19;case 19:for(;r.have<r.nlen+r.ndist;){for(;D=(O=r.lencode[_&(1<<r.lenbits)-1])>>>16&255,k=65535&O,!((S=O>>>24)<=m);){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}if(k<16)_>>>=S,m-=S,r.lens[r.have++]=k;else {if(16===k){for(L=S+2;m<L;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}if(_>>>=S,m-=S,0===r.have){e.msg="invalid bit length repeat",r.mode=d;break}N=r.lens[r.have-1],Q=3+(3&_),_>>>=2,m-=2;}else if(17===k){for(L=S+3;m<L;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}m-=S,N=0,Q=3+(7&(_>>>=S)),_>>>=3,m-=3;}else {for(L=S+7;m<L;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}m-=S,N=0,Q=11+(127&(_>>>=S)),_>>>=7,m-=7;}if(r.have+Q>r.nlen+r.ndist){e.msg="invalid bit length repeat",r.mode=d;break}for(;Q--;)r.lens[r.have++]=N;}}if(r.mode===d)break;if(0===r.lens[256]){e.msg="invalid code -- missing end-of-block",r.mode=d;break}if(r.lenbits=9,x={bits:r.lenbits},M=s(1,r.lens,0,r.nlen,r.lencode,0,r.work,x),r.lenbits=x.bits,M){e.msg="invalid literal/lengths set",r.mode=d;break}if(r.distbits=6,r.distcode=r.distdyn,x={bits:r.distbits},M=s(2,r.lens,r.nlen,r.ndist,r.distcode,0,r.work,x),r.distbits=x.bits,M){e.msg="invalid distances set",r.mode=d;break}if(r.mode=20,6===t)break e;case 20:r.mode=21;case 21:if(C>=6&&I>=258){e.next_out=u,e.avail_out=I,e.next_in=h,e.avail_in=C,r.hold=_,r.bits=m,A(e,E),u=e.next_out,g=e.output,I=e.avail_out,h=e.next_in,f=e.input,C=e.avail_in,_=r.hold,m=r.bits,r.mode===c&&(r.back=-1);break}for(r.back=0;D=(O=r.lencode[_&(1<<r.lenbits)-1])>>>16&255,k=65535&O,!((S=O>>>24)<=m);){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}if(D&&!(240&D)){for(v=S,R=D,F=k;D=(O=r.lencode[F+((_&(1<<v+R)-1)>>v)])>>>16&255,k=65535&O,!(v+(S=O>>>24)<=m);){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}_>>>=v,m-=v,r.back+=v;}if(_>>>=S,m-=S,r.back+=S,r.length=k,0===D){r.mode=26;break}if(32&D){r.back=-1,r.mode=c;break}if(64&D){e.msg="invalid literal/length code",r.mode=d;break}r.extra=15&D,r.mode=22;case 22:if(r.extra){for(L=r.extra;m<L;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}r.length+=_&(1<<r.extra)-1,_>>>=r.extra,m-=r.extra,r.back+=r.extra;}r.was=r.length,r.mode=23;case 23:for(;D=(O=r.distcode[_&(1<<r.distbits)-1])>>>16&255,k=65535&O,!((S=O>>>24)<=m);){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}if(!(240&D)){for(v=S,R=D,F=k;D=(O=r.distcode[F+((_&(1<<v+R)-1)>>v)])>>>16&255,k=65535&O,!(v+(S=O>>>24)<=m);){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}_>>>=v,m-=v,r.back+=v;}if(_>>>=S,m-=S,r.back+=S,64&D){e.msg="invalid distance code",r.mode=d;break}r.offset=k,r.extra=15&D,r.mode=24;case 24:if(r.extra){for(L=r.extra;m<L;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}r.offset+=_&(1<<r.extra)-1,_>>>=r.extra,m-=r.extra,r.back+=r.extra;}if(r.offset>r.dmax){e.msg="invalid distance too far back",r.mode=d;break}r.mode=25;case 25:if(0===I)break e;if(Q=E-I,r.offset>Q){if((Q=r.offset-Q)>r.whave&&r.sane){e.msg="invalid distance too far back",r.mode=d;break}Q>r.wnext?(Q-=r.wnext,y=r.wsize-Q):y=r.wnext-Q,Q>r.length&&(Q=r.length),b=r.window;}else b=g,y=u-r.offset,Q=r.length;Q>I&&(Q=I),I-=Q,r.length-=Q;do{g[u++]=b[y++];}while(--Q);0===r.length&&(r.mode=21);break;case 26:if(0===I)break e;g[u++]=r.length,I--,r.mode=21;break;case 27:if(r.wrap){for(;m<32;){if(0===C)break e;C--,_|=f[h++]<<m,m+=8;}if(E-=I,e.total_out+=E,r.total+=E,E&&(e.adler=r.check=r.flags?a(r.check,g,E,u-E):i(r.check,g,E,u-E)),E=I,(r.flags?_:l(_))!==r.check){e.msg="incorrect data check",r.mode=d;break}_=0,m=0;}r.mode=28;case 28:if(r.wrap&&r.flags){for(;m<32;){if(0===C)break e;C--,_+=f[h++]<<m,m+=8;}if(_!==(4294967295&r.total)){e.msg="incorrect length check",r.mode=d;break}_=0,m=0;}r.mode=29;case 29:M=1;break e;case d:M=-3;break e;case 31:return -4;default:return o}return e.next_out=u,e.avail_out=I,e.next_in=h,e.avail_in=C,r.hold=_,r.bits=m,(r.wsize||E!==e.avail_out&&r.mode<d&&(r.mode<27||4!==t))&&p(e,e.output,e.next_out,E-e.avail_out)?(r.mode=31,-4):(w-=e.avail_in,E-=e.avail_out,e.total_in+=w,e.total_out+=E,r.total+=E,r.wrap&&E&&(e.adler=r.check=r.flags?a(r.check,g,E,e.next_out-E):i(r.check,g,E,e.next_out-E)),e.data_type=r.bits+(r.last?64:0)+(r.mode===c?128:0)+(20===r.mode||15===r.mode?256:0),(0===w&&0===E||4===t)&&0===M&&(M=-5),M)},t.inflateEnd=function(e){if(!e||!e.state)return o;var t=e.state;return t.window&&(t.window=null),e.state=null,0},t.inflateGetHeader=function(e,t){var r;return e&&e.state&&2&(r=e.state).wrap?(r.head=t,t.done=!1,0):o},t.inflateSetDictionary=function(e,t){var r,n=t.length;return e&&e.state?0!==(r=e.state).wrap&&11!==r.mode?o:11===r.mode&&i(1,t,n,0)!==r.check?-3:p(e,t,n,n)?(r.mode=31,-4):(r.havedict=1,0):o},t.inflateInfo="pako inflate (from Nodeca project)";},1998:(e,t,r)=>{var n=r(9805),i=[3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0],a=[16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78],A=[1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0],s=[16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64];e.exports=function(e,t,r,o,c,d,l,f){var g,h,u,C,I,_,m,B,p,w=f.bits,E=0,Q=0,y=0,b=0,S=0,D=0,k=0,v=0,R=0,F=0,N=null,M=0,x=new n.Buf16(16),L=new n.Buf16(16),O=null,T=0;for(E=0;E<=15;E++)x[E]=0;for(Q=0;Q<o;Q++)x[t[r+Q]]++;for(S=w,b=15;b>=1&&0===x[b];b--);if(S>b&&(S=b),0===b)return c[d++]=20971520,c[d++]=20971520,f.bits=1,0;for(y=1;y<b&&0===x[y];y++);for(S<y&&(S=y),v=1,E=1;E<=15;E++)if(v<<=1,(v-=x[E])<0)return -1;if(v>0&&(0===e||1!==b))return -1;for(L[1]=0,E=1;E<15;E++)L[E+1]=L[E]+x[E];for(Q=0;Q<o;Q++)0!==t[r+Q]&&(l[L[t[r+Q]]++]=Q);if(0===e?(N=O=l,_=19):1===e?(N=i,M-=257,O=a,T-=257,_=256):(N=A,O=s,_=-1),F=0,Q=0,E=y,I=d,D=S,k=0,u=-1,C=(R=1<<S)-1,1===e&&R>852||2===e&&R>592)return 1;for(;;){m=E-k,l[Q]<_?(B=0,p=l[Q]):l[Q]>_?(B=O[T+l[Q]],p=N[M+l[Q]]):(B=96,p=0),g=1<<E-k,y=h=1<<D;do{c[I+(F>>k)+(h-=g)]=m<<24|B<<16|p;}while(0!==h);for(g=1<<E-1;F&g;)g>>=1;if(0!==g?(F&=g-1,F+=g):F=0,Q++,0==--x[E]){if(E===b)break;E=t[r+l[Q]];}if(E>S&&(F&C)!==u){for(0===k&&(k=S),I+=y,v=1<<(D=E-k);D+k<b&&!((v-=x[D+k])<=0);)D++,v<<=1;if(R+=1<<D,1===e&&R>852||2===e&&R>592)return 1;c[u=F&C]=S<<24|D<<16|I-d;}}return 0!==F&&(c[I+F]=E-k<<24|64<<16),f.bits=S,0};},4674:e=>{e.exports={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible version"};},3665:(e,t,r)=>{var n=r(9805);function i(e){for(var t=e.length;--t>=0;)e[t]=0;}var a=[0,0,0,0,0,0,0,0,1,1,1,1,2,2,2,2,3,3,3,3,4,4,4,4,5,5,5,5,0],A=[0,0,0,0,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13],s=[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,3,7],o=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15],c=new Array(576);i(c);var d=new Array(60);i(d);var l=new Array(512);i(l);var f=new Array(256);i(f);var g=new Array(29);i(g);var h,u,C,I=new Array(30);function _(e,t,r,n,i){this.static_tree=e,this.extra_bits=t,this.extra_base=r,this.elems=n,this.max_length=i,this.has_stree=e&&e.length;}function m(e,t){this.dyn_tree=e,this.max_code=0,this.stat_desc=t;}function B(e){return e<256?l[e]:l[256+(e>>>7)]}function p(e,t){e.pending_buf[e.pending++]=255&t,e.pending_buf[e.pending++]=t>>>8&255;}function w(e,t,r){e.bi_valid>16-r?(e.bi_buf|=t<<e.bi_valid&65535,p(e,e.bi_buf),e.bi_buf=t>>16-e.bi_valid,e.bi_valid+=r-16):(e.bi_buf|=t<<e.bi_valid&65535,e.bi_valid+=r);}function E(e,t,r){w(e,r[2*t],r[2*t+1]);}function Q(e,t){var r=0;do{r|=1&e,e>>>=1,r<<=1;}while(--t>0);return r>>>1}function y(e,t,r){var n,i,a=new Array(16),A=0;for(n=1;n<=15;n++)a[n]=A=A+r[n-1]<<1;for(i=0;i<=t;i++){var s=e[2*i+1];0!==s&&(e[2*i]=Q(a[s]++,s));}}function b(e){var t;for(t=0;t<286;t++)e.dyn_ltree[2*t]=0;for(t=0;t<30;t++)e.dyn_dtree[2*t]=0;for(t=0;t<19;t++)e.bl_tree[2*t]=0;e.dyn_ltree[512]=1,e.opt_len=e.static_len=0,e.last_lit=e.matches=0;}function S(e){e.bi_valid>8?p(e,e.bi_buf):e.bi_valid>0&&(e.pending_buf[e.pending++]=e.bi_buf),e.bi_buf=0,e.bi_valid=0;}function D(e,t,r,n){var i=2*t,a=2*r;return e[i]<e[a]||e[i]===e[a]&&n[t]<=n[r]}function k(e,t,r){for(var n=e.heap[r],i=r<<1;i<=e.heap_len&&(i<e.heap_len&&D(t,e.heap[i+1],e.heap[i],e.depth)&&i++,!D(t,n,e.heap[i],e.depth));)e.heap[r]=e.heap[i],r=i,i<<=1;e.heap[r]=n;}function v(e,t,r){var n,i,s,o,c=0;if(0!==e.last_lit)do{n=e.pending_buf[e.d_buf+2*c]<<8|e.pending_buf[e.d_buf+2*c+1],i=e.pending_buf[e.l_buf+c],c++,0===n?E(e,i,t):(E(e,(s=f[i])+256+1,t),0!==(o=a[s])&&w(e,i-=g[s],o),E(e,s=B(--n),r),0!==(o=A[s])&&w(e,n-=I[s],o));}while(c<e.last_lit);E(e,256,t);}function R(e,t){var r,n,i,a=t.dyn_tree,A=t.stat_desc.static_tree,s=t.stat_desc.has_stree,o=t.stat_desc.elems,c=-1;for(e.heap_len=0,e.heap_max=573,r=0;r<o;r++)0!==a[2*r]?(e.heap[++e.heap_len]=c=r,e.depth[r]=0):a[2*r+1]=0;for(;e.heap_len<2;)a[2*(i=e.heap[++e.heap_len]=c<2?++c:0)]=1,e.depth[i]=0,e.opt_len--,s&&(e.static_len-=A[2*i+1]);for(t.max_code=c,r=e.heap_len>>1;r>=1;r--)k(e,a,r);i=o;do{r=e.heap[1],e.heap[1]=e.heap[e.heap_len--],k(e,a,1),n=e.heap[1],e.heap[--e.heap_max]=r,e.heap[--e.heap_max]=n,a[2*i]=a[2*r]+a[2*n],e.depth[i]=(e.depth[r]>=e.depth[n]?e.depth[r]:e.depth[n])+1,a[2*r+1]=a[2*n+1]=i,e.heap[1]=i++,k(e,a,1);}while(e.heap_len>=2);e.heap[--e.heap_max]=e.heap[1],function(e,t){var r,n,i,a,A,s,o=t.dyn_tree,c=t.max_code,d=t.stat_desc.static_tree,l=t.stat_desc.has_stree,f=t.stat_desc.extra_bits,g=t.stat_desc.extra_base,h=t.stat_desc.max_length,u=0;for(a=0;a<=15;a++)e.bl_count[a]=0;for(o[2*e.heap[e.heap_max]+1]=0,r=e.heap_max+1;r<573;r++)(a=o[2*o[2*(n=e.heap[r])+1]+1]+1)>h&&(a=h,u++),o[2*n+1]=a,n>c||(e.bl_count[a]++,A=0,n>=g&&(A=f[n-g]),s=o[2*n],e.opt_len+=s*(a+A),l&&(e.static_len+=s*(d[2*n+1]+A)));if(0!==u){do{for(a=h-1;0===e.bl_count[a];)a--;e.bl_count[a]--,e.bl_count[a+1]+=2,e.bl_count[h]--,u-=2;}while(u>0);for(a=h;0!==a;a--)for(n=e.bl_count[a];0!==n;)(i=e.heap[--r])>c||(o[2*i+1]!==a&&(e.opt_len+=(a-o[2*i+1])*o[2*i],o[2*i+1]=a),n--);}}(e,t),y(a,c,e.bl_count);}function F(e,t,r){var n,i,a=-1,A=t[1],s=0,o=7,c=4;for(0===A&&(o=138,c=3),t[2*(r+1)+1]=65535,n=0;n<=r;n++)i=A,A=t[2*(n+1)+1],++s<o&&i===A||(s<c?e.bl_tree[2*i]+=s:0!==i?(i!==a&&e.bl_tree[2*i]++,e.bl_tree[32]++):s<=10?e.bl_tree[34]++:e.bl_tree[36]++,s=0,a=i,0===A?(o=138,c=3):i===A?(o=6,c=3):(o=7,c=4));}function N(e,t,r){var n,i,a=-1,A=t[1],s=0,o=7,c=4;for(0===A&&(o=138,c=3),n=0;n<=r;n++)if(i=A,A=t[2*(n+1)+1],!(++s<o&&i===A)){if(s<c)do{E(e,i,e.bl_tree);}while(0!=--s);else 0!==i?(i!==a&&(E(e,i,e.bl_tree),s--),E(e,16,e.bl_tree),w(e,s-3,2)):s<=10?(E(e,17,e.bl_tree),w(e,s-3,3)):(E(e,18,e.bl_tree),w(e,s-11,7));s=0,a=i,0===A?(o=138,c=3):i===A?(o=6,c=3):(o=7,c=4);}}i(I);var M=!1;function x(e,t,r,i){w(e,0+(i?1:0),3),function(e,t,r){S(e),p(e,r),p(e,~r),n.arraySet(e.pending_buf,e.window,t,r,e.pending),e.pending+=r;}(e,t,r);}t._tr_init=function(e){M||(function(){var e,t,r,n,i,o=new Array(16);for(r=0,n=0;n<28;n++)for(g[n]=r,e=0;e<1<<a[n];e++)f[r++]=n;for(f[r-1]=n,i=0,n=0;n<16;n++)for(I[n]=i,e=0;e<1<<A[n];e++)l[i++]=n;for(i>>=7;n<30;n++)for(I[n]=i<<7,e=0;e<1<<A[n]-7;e++)l[256+i++]=n;for(t=0;t<=15;t++)o[t]=0;for(e=0;e<=143;)c[2*e+1]=8,e++,o[8]++;for(;e<=255;)c[2*e+1]=9,e++,o[9]++;for(;e<=279;)c[2*e+1]=7,e++,o[7]++;for(;e<=287;)c[2*e+1]=8,e++,o[8]++;for(y(c,287,o),e=0;e<30;e++)d[2*e+1]=5,d[2*e]=Q(e,5);h=new _(c,a,257,286,15),u=new _(d,A,0,30,15),C=new _(new Array(0),s,0,19,7);}(),M=!0),e.l_desc=new m(e.dyn_ltree,h),e.d_desc=new m(e.dyn_dtree,u),e.bl_desc=new m(e.bl_tree,C),e.bi_buf=0,e.bi_valid=0,b(e);},t._tr_stored_block=x,t._tr_flush_block=function(e,t,r,n){var i,a,A=0;e.level>0?(2===e.strm.data_type&&(e.strm.data_type=function(e){var t,r=4093624447;for(t=0;t<=31;t++,r>>>=1)if(1&r&&0!==e.dyn_ltree[2*t])return 0;if(0!==e.dyn_ltree[18]||0!==e.dyn_ltree[20]||0!==e.dyn_ltree[26])return 1;for(t=32;t<256;t++)if(0!==e.dyn_ltree[2*t])return 1;return 0}(e)),R(e,e.l_desc),R(e,e.d_desc),A=function(e){var t;for(F(e,e.dyn_ltree,e.l_desc.max_code),F(e,e.dyn_dtree,e.d_desc.max_code),R(e,e.bl_desc),t=18;t>=3&&0===e.bl_tree[2*o[t]+1];t--);return e.opt_len+=3*(t+1)+5+5+4,t}(e),i=e.opt_len+3+7>>>3,(a=e.static_len+3+7>>>3)<=i&&(i=a)):i=a=r+5,r+4<=i&&-1!==t?x(e,t,r,n):4===e.strategy||a===i?(w(e,2+(n?1:0),3),v(e,c,d)):(w(e,4+(n?1:0),3),function(e,t,r,n){var i;for(w(e,t-257,5),w(e,r-1,5),w(e,n-4,4),i=0;i<n;i++)w(e,e.bl_tree[2*o[i]+1],3);N(e,e.dyn_ltree,t-1),N(e,e.dyn_dtree,r-1);}(e,e.l_desc.max_code+1,e.d_desc.max_code+1,A+1),v(e,e.dyn_ltree,e.dyn_dtree)),b(e),n&&S(e);},t._tr_tally=function(e,t,r){return e.pending_buf[e.d_buf+2*e.last_lit]=t>>>8&255,e.pending_buf[e.d_buf+2*e.last_lit+1]=255&t,e.pending_buf[e.l_buf+e.last_lit]=255&r,e.last_lit++,0===t?e.dyn_ltree[2*r]++:(e.matches++,t--,e.dyn_ltree[2*(f[r]+256+1)]++,e.dyn_dtree[2*B(t)]++),e.last_lit===e.lit_bufsize-1},t._tr_align=function(e){w(e,2,3),E(e,256,c),function(e){16===e.bi_valid?(p(e,e.bi_buf),e.bi_buf=0,e.bi_valid=0):e.bi_valid>=8&&(e.pending_buf[e.pending++]=255&e.bi_buf,e.bi_buf>>=8,e.bi_valid-=8);}(e);};},4442:e=>{e.exports=function(){this.input=null,this.next_in=0,this.avail_in=0,this.total_in=0,this.output=null,this.next_out=0,this.avail_out=0,this.total_out=0,this.msg="",this.state=null,this.data_type=2,this.adler=0;};},7392:e=>{class t{constructor(e={}){if(!(e.maxSize&&e.maxSize>0))throw new TypeError("`maxSize` must be a number greater than 0");this.maxSize=e.maxSize,this.cache=new Map,this.oldCache=new Map,this._size=0;}_set(e,t){this.cache.set(e,t),this._size++,this._size>=this.maxSize&&(this._size=0,this.oldCache=this.cache,this.cache=new Map);}get(e){if(this.cache.has(e))return this.cache.get(e);if(this.oldCache.has(e)){const t=this.oldCache.get(e);return this.oldCache.delete(e),this._set(e,t),t}}set(e,t){return this.cache.has(e)?this.cache.set(e,t):this._set(e,t),this}has(e){return this.cache.has(e)||this.oldCache.has(e)}peek(e){return this.cache.has(e)?this.cache.get(e):this.oldCache.has(e)?this.oldCache.get(e):void 0}delete(e){const t=this.cache.delete(e);return t&&this._size--,this.oldCache.delete(e)||t}clear(){this.cache.clear(),this.oldCache.clear(),this._size=0;}*keys(){for(const[e]of this)yield e;}*values(){for(const[,e]of this)yield e;}*[Symbol.iterator](){for(const e of this.cache)yield e;for(const e of this.oldCache){const[t]=e;this.cache.has(t)||(yield e);}}get size(){let e=0;for(const t of this.oldCache.keys())this.cache.has(t)||e++;return this._size+e}}e.exports=t;},1307:function(e,t,r){var n;n=e=>(()=>{var t=[,e=>{e.exports="data:application/wasm;base64,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";},t=>{t.exports=e;}],r={};function n(e){var i=r[e];if(void 0!==i)return i.exports;var a=r[e]={exports:{}};return t[e](a,a.exports,n),a.exports}n.d=(e,t)=>{for(var r in t)n.o(t,r)&&!n.o(e,r)&&Object.defineProperty(e,r,{enumerable:!0,get:t[r]});},n.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t),n.r=e=>{"undefined"!=typeof Symbol&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0});};var i={};return (()=>{n.r(i),n.d(i,{XzReadableStream:()=>a});var e=n(1);const t=globalThis.ReadableStream||n(2).ReadableStream;class r{constructor(e){this.exports=e.exports,this.memory=this.exports.memory,this.ptr=this.exports.create_context(),this._refresh(),this.bufSize=this.mem32[0],this.inStart=this.mem32[1]-this.ptr,this.inEnd=this.inStart+this.bufSize,this.outStart=this.mem32[4]-this.ptr;}supplyInput(e){this._refresh(),this.mem8.subarray(this.inStart,this.inEnd).set(e,0),this.exports.supply_input(this.ptr,e.byteLength),this._refresh();}getNextOutput(){const e=this.exports.get_next_output(this.ptr);if(this._refresh(),0!==e&&1!==e)throw new Error(`get_next_output failed with error code ${e}`);return {outChunk:this.mem8.slice(this.outStart,this.outStart+this.mem32[5]),finished:1===e}}needsMoreInput(){return this.mem32[2]===this.mem32[3]}outputBufferIsFull(){return this.mem32[5]===this.bufSize}resetOutputBuffer(){this.outPos=this.mem32[5]=0;}dispose(){this.exports.destroy_context(this.ptr),this.exports=null;}_refresh(){this.memory.buffer!==this.mem8?.buffer&&(this.mem8=new Uint8Array(this.memory.buffer,this.ptr),this.mem32=new Uint32Array(this.memory.buffer,this.ptr));}}class a extends t{static _moduleInstancePromise;static _moduleInstance;static async _getModuleInstance(){const t=e.replace("data:application/wasm;base64,",""),r=Uint8Array.from(atob(t),(e=>e.charCodeAt(0))).buffer,n=await WebAssembly.instantiate(r,{});a._moduleInstance=n.instance;}constructor(e){let t,n=null;const i=e.getReader();super({async start(e){a._moduleInstance||await(a._moduleInstancePromise||(a._moduleInstancePromise=a._getModuleInstance())),t=new r(a._moduleInstance);},async pull(e){if(t.needsMoreInput()){if(null===n||0===n.byteLength){const{done:e,value:t}=await i.read();e||(n=t);}const e=Math.min(t.bufSize,n.byteLength);t.supplyInput(n.subarray(0,e)),n=n.subarray(e);}const r=t.getNextOutput();e.enqueue(r.outChunk),t.resetOutputBuffer(),r.finished&&(t.dispose(),e.close());},cancel:()=>(t.dispose(),i.cancel())});}}})(),i})(),e.exports=n(r(772));},7937:()=>{},772:()=>{},86:(e,t,r)=>{const n=r(1308).A;e.exports=n,e.exports.default=n;},1308:(e,t)=>{let r=[0,1996959894,3993919788,2567524794,124634137,1886057615,3915621685,2657392035,249268274,2044508324,3772115230,2547177864,162941995,2125561021,3887607047,2428444049,498536548,1789927666,4089016648,2227061214,450548861,1843258603,4107580753,2211677639,325883990,1684777152,4251122042,2321926636,335633487,1661365465,4195302755,2366115317,997073096,1281953886,3579855332,2724688242,1006888145,1258607687,3524101629,2768942443,901097722,1119000684,3686517206,2898065728,853044451,1172266101,3705015759,2882616665,651767980,1373503546,3369554304,3218104598,565507253,1454621731,3485111705,3099436303,671266974,1594198024,3322730930,2970347812,795835527,1483230225,3244367275,3060149565,1994146192,31158534,2563907772,4023717930,1907459465,112637215,2680153253,3904427059,2013776290,251722036,2517215374,3775830040,2137656763,141376813,2439277719,3865271297,1802195444,476864866,2238001368,4066508878,1812370925,453092731,2181625025,4111451223,1706088902,314042704,2344532202,4240017532,1658658271,366619977,2362670323,4224994405,1303535960,984961486,2747007092,3569037538,1256170817,1037604311,2765210733,3554079995,1131014506,879679996,2909243462,3663771856,1141124467,855842277,2852801631,3708648649,1342533948,654459306,3188396048,3373015174,1466479909,544179635,3110523913,3462522015,1591671054,702138776,2966460450,3352799412,1504918807,783551873,3082640443,3233442989,3988292384,2596254646,62317068,1957810842,3939845945,2647816111,81470997,1943803523,3814918930,2489596804,225274430,2053790376,3826175755,2466906013,167816743,2097651377,4027552580,2265490386,503444072,1762050814,4150417245,2154129355,426522225,1852507879,4275313526,2312317920,282753626,1742555852,4189708143,2394877945,397917763,1622183637,3604390888,2714866558,953729732,1340076626,3518719985,2797360999,1068828381,1219638859,3624741850,2936675148,906185462,1090812512,3747672003,2825379669,829329135,1181335161,3412177804,3160834842,628085408,1382605366,3423369109,3138078467,570562233,1426400815,3317316542,2998733608,733239954,1555261956,3268935591,3050360625,752459403,1541320221,2607071920,3965973030,1969922972,40735498,2617837225,3943577151,1913087877,83908371,2512341634,3803740692,2075208622,213261112,2463272603,3855990285,2094854071,198958881,2262029012,4057260610,1759359992,534414190,2176718541,4139329115,1873836001,414664567,2282248934,4279200368,1711684554,285281116,2405801727,4167216745,1634467795,376229701,2685067896,3608007406,1308918612,956543938,2808555105,3495958263,1231636301,1047427035,2932959818,3654703836,1088359270,936918e3,2847714899,3736837829,1202900863,817233897,3183342108,3401237130,1404277552,615818150,3134207493,3453421203,1423857449,601450431,3009837614,3294710456,1567103746,711928724,3020668471,3272380065,1510334235,755167117];"undefined"!=typeof Int32Array&&(r=new Int32Array(r)),t.A=(e,t)=>{let n=0===t?0:~t;for(let t=0;t<e.length;t++)n=r[255&(n^e[t])]^n>>>8;return ~n};}},t={};function r(n){var i=t[n];if(void 0!==i)return i.exports;var a=t[n]={exports:{}};return e[n].call(a.exports,a,a.exports,r),a.exports}r.n=e=>{var t=e&&e.__esModule?()=>e.default:()=>e;return r.d(t,{a:t}),t},r.d=(e,t)=>{for(var n in t)r.o(t,n)&&!r.o(e,n)&&Object.defineProperty(e,n,{enumerable:!0,get:t[n]});},r.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t),r.r=e=>{"undefined"!=typeof Symbol&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0});};var n=r(7806);return n})();
+   var gmodCRAM = (()=>{var e={24:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.toHex=function(e){let t="";for(let r=0,i=e.length;r<i;r++)t+=n[e[r]];return t};const r=["0","1","2","3","4","5","6","7","8","9","A","B","C","D","E","F"],n=new Array(256);for(let e=0;e<256;e++)n[e]=`${r[e>>>4&15]}${r[15&e]}`;},78:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0});const n=r(24),i=[0,1,3,7,15,31,63,127,255];t.default=class{constructor(e){this.stream=e,this.bitOffset=0,this.curByte=0,this.hasByte=!1;}_ensureByte(){this.hasByte||(this.curByte=this.stream.readByte(),this.hasByte=!0);}read(e){let t=0;for(;e>0;){this._ensureByte();const r=8-this.bitOffset;if(e>=r)t<<=r,t|=i[r]&this.curByte,this.hasByte=!1,this.bitOffset=0,e-=r;else {t<<=e;const n=r-e;t|=(this.curByte&i[e]<<n)>>n,this.bitOffset+=e,e=0;}}return t}seek(e){const t=e%8,r=(e-t)/8;this.bitOffset=t,this.stream.seek(r),this.hasByte=!1;}pi(){const e=new Uint8Array(6);for(let t=0;t<e.length;t++)e[t]=this.read(8);return (0, n.toHex)(e)}};},86:(e,t,r)=>{const n=r(1308).A;e.exports=n,e.exports.default=n;},500:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=r(6272),a=r(6761),s=n(r(588)),A=n(r(9685)),o=n(r(7480)),c=r(7580),d=r(2549);function l(e,t,r,n){const a=!!(n.mate||void 0!==n.mateRecordNumber&&n.mateRecordNumber!==t);r.readName||(r.readName=String(r.uniqueId),n.readName=r.readName),r.mate={sequenceId:n.sequenceId,alignmentStart:n.alignmentStart,uniqueId:n.uniqueId},n.readName&&(r.mate.readName=n.readName),n.mate||void 0!==n.mateRecordNumber||(n.mate={sequenceId:r.sequenceId,alignmentStart:r.alignmentStart,uniqueId:r.uniqueId},r.readName&&(n.mate.readName=r.readName)),r.flags|=s.default.BAM_FPAIRED,n.flags&s.default.BAM_FUNMAP&&(r.flags|=s.default.BAM_FMUNMAP),r.flags&s.default.BAM_FUNMAP&&(n.flags|=s.default.BAM_FMUNMAP),n.flags&s.default.BAM_FREVERSE&&(r.flags|=s.default.BAM_FMREVERSE),r.flags&s.default.BAM_FREVERSE&&(n.flags|=s.default.BAM_FMREVERSE),void 0===r.templateLength&&(a?function(e,t,r){const n=function t(r){const n=[r];if(void 0!==r.mateRecordNumber&&r.mateRecordNumber>=0){const a=e[r.mateRecordNumber];if(!a)throw new i.CramMalformedError("intra-slice mate record not found, this file seems malformed");n.push(...t(a));}return n}(r),a=n.map((e=>e.alignmentStart)),s=n.map((e=>e.alignmentStart+e.readLength-1)),A=Math.max(...s)-Math.min(...a)+1;A>=0&&n.forEach((e=>{if(void 0!==e.templateLength)throw new i.CramMalformedError("mate pair group has some members that have template lengths already, this file seems malformed");e.templateLength=A;}));}(e,0,r):function(e,t){const r=Math.min(e.alignmentStart,t.alignmentStart),n=Math.max(e.alignmentStart+e.readLength-1,t.alignmentStart+t.readLength-1)-r+1;e.templateLength=n,t.templateLength=n;}(r,n)),r.mateRecordNumber=void 0;}class f{constructor(e,t,r){this.container=e,this.containerPosition=t,this.sliceSize=r,this.file=e.file;}async getHeader(){const{majorVersion:e}=await this.file.getDefinition(),t=(0, c.getSectionParsers)(e),r=await this.container.getHeader(),n=await this.file.readBlock(r._endPosition+this.containerPosition);if("MAPPED_SLICE_HEADER"===n.contentType){const e=(0, d.parseItem)(n.content,t.cramMappedSliceHeader.parser,0,r._endPosition);return {...n,parsedContent:e}}if("UNMAPPED_SLICE_HEADER"===n.contentType){const e=(0, d.parseItem)(n.content,t.cramUnmappedSliceHeader.parser,0,r._endPosition);return {...n,parsedContent:e}}throw new i.CramMalformedError(`error reading slice header block, invalid content type ${n.contentType}`)}async getBlocks(){const e=await this.getHeader();let t=e._endPosition;const r=new Array(e.parsedContent.numBlocks);for(let e=0;e<r.length;e++){const n=await this.file.readBlock(t);r[e]=n,t=r[e]._endPosition;}return r}async getCoreDataBlock(){return (await this.getBlocks())[0]}async _getBlocksContentIdIndex(){const e=await this.getBlocks(),t={};return e.forEach((e=>{"EXTERNAL_DATA"===e.contentType&&(t[e.contentId]=e);})),t}async getBlockByContentId(e){return (await this._getBlocksContentIdIndex())[e]}async getReferenceRegion(){const e=new TextDecoder("utf8"),t=(await this.getHeader()).parsedContent;if(!(0, c.isMappedSliceHeader)(t))throw new Error("slice header not mapped");if(t.refSeqId<0)return;const r=await this.container.getCompressionScheme();if(void 0===r)throw new Error("compression scheme undefined");if(t.refBaseBlockId>=0){const r=await this.getBlockByContentId(t.refBaseBlockId);if(!r)throw new i.CramMalformedError("embedded reference specified, but reference block does not exist");return {seq:e.decode(r.data),start:t.refSeqStart,end:t.refSeqStart+t.refSeqSpan-1,span:t.refSeqSpan}}if(r.referenceRequired||this.file.fetchReferenceSequenceCallback){if(!this.file.fetchReferenceSequenceCallback)throw new Error("reference sequence not embedded, and seqFetch callback not provided, cannot fetch reference sequence");const e=await this.file.fetchReferenceSequenceCallback(t.refSeqId,t.refSeqStart,t.refSeqStart+t.refSeqSpan-1);if(e.length!==t.refSeqSpan)throw new i.CramArgumentError("seqFetch callback returned a reference sequence of the wrong length");return {seq:e,start:t.refSeqStart,end:t.refSeqStart+t.refSeqSpan-1,span:t.refSeqSpan}}}getAllRecords(){return this.getRecords((()=>!0))}async _fetchRecords(){const{majorVersion:e}=await this.file.getDefinition(),t=await this.container.getCompressionScheme();if(void 0===t)throw new Error("compression scheme undefined");const r=await this.getHeader(),n=await this._getBlocksContentIdIndex();if(e>1&&this.file.options.checkSequenceMD5&&(0, c.isMappedSliceHeader)(r.parsedContent)&&r.parsedContent.refSeqId>=0&&"0000000000000000"!==r.parsedContent.md5?.join("")){const e=await this.getReferenceRegion();if(e){const{seq:t,start:n,end:a}=e,s=(0, d.sequenceMD5)(t),A=r.parsedContent.md5?.map((e=>(e<16?"0":"")+e.toString(16))).join("");if(s!==A)throw new i.CramMalformedError(`MD5 checksum reference mismatch for ref ${r.parsedContent.refSeqId} pos ${n}..${a}. recorded MD5: ${A}, calculated MD5: ${s}`)}}const s=await this.getCoreDataBlock(),f={lastAlignmentStart:(0, c.isMappedSliceHeader)(r.parsedContent)?r.parsedContent.refSeqStart:0,coreBlock:{bitPosition:7,bytePosition:0},externalBlocks:{map:new Map,getCursor(e){let t=this.map.get(e);return void 0===t&&(t={bitPosition:7,bytePosition:0},this.map.set(e,t)),t}}},u=e=>{const r=t.getCodecForDataSeries(e);if(!r)throw new i.CramMalformedError(`no codec defined for ${e} data series`);return r.decode(this,s,n,f)},g=new Array(r.parsedContent.numRecords);for(let i=0;i<g.length;i+=1)try{const a=(0,A.default)(this,u,t,r,s,n,f,e,i);g[i]=new o.default({...a,uniqueId:r.contentPosition+r.parsedContent.recordCounter+i+1});}catch(e){if(e instanceof a.CramBufferOverrunError){console.warn("read attempted beyond end of buffer, file seems truncated.");break}throw e}for(let e=0;e<g.length;e+=1){const t=g[e];if(t){const{mateRecordNumber:r}=t;void 0!==r&&r>=0&&g[r]&&l(g,e,t,g[r]);}}return g}async getRecords(e){const t=this.container.filePosition+this.containerPosition;let r=this.file.featureCache.get(t.toString());r||(r=this._fetchRecords(),this.file.featureCache.set(t.toString(),r));const n=(await r).filter(e);if(n.length&&this.file.fetchReferenceSequenceCallback){const e=await this.getHeader();if((0, c.isMappedSliceHeader)(e.parsedContent)&&(e.parsedContent.refSeqId>=0||-2===e.parsedContent.refSeqId)){const t=e.parsedContent.refSeqId>=0?e.parsedContent.refSeqId:void 0,r=await this.container.getCompressionScheme();if(void 0===r)throw new Error("compression scheme undefined");const i={};for(const e of n){const r=void 0!==t?t:e.sequenceId;let n=i[r];n||(n={id:r,start:e.alignmentStart,end:Number.NEGATIVE_INFINITY,seq:null},i[r]=n);const a=e.alignmentStart+(e.lengthOnRef||e.readLength)-1;a>n.end&&(n.end=a),e.alignmentStart<n.start&&(n.start=e.alignmentStart);}await Promise.all(Object.values(i).map((async e=>{-1!==e.id&&e.start<=e.end&&this.file.fetchReferenceSequenceCallback&&(e.seq=await this.file.fetchReferenceSequenceCallback(e.id,e.start,e.end));})));for(const e of n){const n=i[void 0!==t?t:e.sequenceId];if(n?.seq){const t=n.seq;e.addReferenceSequence({...n,seq:t},r);}}}}return n}}t.default=f,"getHeader getBlocks _getBlocksContentIdIndex".split(" ").forEach((e=>{(0, d.tinyMemoize)(f,e);}));},588:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default={CRAM_FLAG_PRESERVE_QUAL_SCORES:1,CRAM_FLAG_DETACHED:2,CRAM_FLAG_MATE_DOWNSTREAM:4,CRAM_FLAG_NO_SEQ:8,CRAM_FLAG_MASK:15,CRAM_M_REVERSE:1,CRAM_M_UNMAP:2,BAM_FPAIRED:1,BAM_FPROPER_PAIR:2,BAM_FUNMAP:4,BAM_FMUNMAP:8,BAM_FREVERSE:16,BAM_FMREVERSE:32,BAM_FREAD1:64,BAM_FREAD2:128,BAM_FSECONDARY:256,BAM_FQCFAIL:512,BAM_FDUP:1024,BAM_FSUPPLEMENTARY:2048,BAM_CMATCH:0,BAM_CINS:1,BAM_CDEL:2,BAM_CREF_SKIP:3,BAM_CSOFT_CLIP:4,BAM_CHARD_CLIP:5,BAM_CPAD:6,BAM_CEQUAL:7,BAM_CDIFF:8,BAM_CBACK:9,BAM_CIGAR_STR:"MIDNSHP:XB",BAM_CIGAR_SHIFT:4,BAM_CIGAR_MASK:15,BAM_CIGAR_TYPE:246183};},632:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(6761),s=r(6272);class A extends i.default{constructor(e,t){if(super(e,t),"int"!==this.dataType)throw new s.CramUnimplementedError(`${this.dataType} decoding not yet implemented by GAMMA codec`)}decode(e,t,r,n){let i=1;for(;0===(0, a.getBits)(t.content,n.coreBlock,1);)i+=1;return ((0, a.getBits)(t.content,n.coreBlock,i-1)|1<<i-1)-this.parameters.offset}}t.default=A;},652:e=>{function t(e){return !!e.constructor&&"function"==typeof e.constructor.isBuffer&&e.constructor.isBuffer(e)}e.exports=function(e){return null!=e&&(t(e)||function(e){return "function"==typeof e.readFloatLE&&"function"==typeof e.slice&&t(e.slice(0,0))}(e)||!!e._isBuffer)};},772:()=>{},807:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(6761),s=r(6272);class A extends i.default{constructor(e,t){if(super(e,t),"int"!==this.dataType)throw new s.CramUnimplementedError(`${this.dataType} decoding not yet implemented by BETA codec`)}decode(e,t,r,n){return (0, a.getBits)(t.content,n.coreBlock,this.parameters.length)-this.parameters.offset}}t.default=A;},870:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.decode=function(e,t,r){const n=f(e),i=u(t),a=new l(n,i);for(;!("eof"in n)||!n.eof();)if(a._init_block())a._read_bunzip();else {const e=a.reader.read(32)>>>0;if(e!==a.streamCRC&&d(o.DATA_ERROR,"Bad stream CRC (got "+a.streamCRC.toString(16)+" expected "+e.toString(16)+")"),!r||!("eof"in n)||n.eof())break;a._start_bunzip(n,i);}if("getBuffer"in i)return i.getBuffer()};const i=n(r(78)),a=n(r(8761)),s=n(r(6612)),A=function(e,t){const r=e[t];for(let r=t;r>0;r--)e[r]=e[r-1];return e[0]=r,r},o={OK:0,LAST_BLOCK:-1,NOT_BZIP_DATA:-2,UNEXPECTED_INPUT_EOF:-3,UNEXPECTED_OUTPUT_EOF:-4,DATA_ERROR:-5,OUT_OF_MEMORY:-6,OBSOLETE_INPUT:-7,END_OF_BLOCK:-8},c={};c[o.LAST_BLOCK]="Bad file checksum",c[o.NOT_BZIP_DATA]="Not bzip data",c[o.UNEXPECTED_INPUT_EOF]="Unexpected input EOF",c[o.UNEXPECTED_OUTPUT_EOF]="Unexpected output EOF",c[o.DATA_ERROR]="Data error",c[o.OUT_OF_MEMORY]="Out of memory",c[o.OBSOLETE_INPUT]="Obsolete (pre 0.9.5) bzip format not supported.";const d=function(e,t){let r=c[e]||"unknown error";t&&(r+=": "+t);const n=new TypeError(r);throw n.errorCode=e,n};class l{constructor(e,t){this.writePos=this.writeCurrent=this.writeCount=0,this._start_bunzip(e,t);}_init_block(){return this._get_next_block()?(this.blockCRC=new a.default,!0):(this.writeCount=-1,!1)}_start_bunzip(e,t){const r=new Uint8Array(4);4===e.read(r,0,4)&&"BZh"===String.fromCharCode(r[0],r[1],r[2])||d(o.NOT_BZIP_DATA,"bad magic");const n=r[3]-48;(n<1||n>9)&&d(o.NOT_BZIP_DATA,"level out of range"),this.reader=new i.default(e),this.dbufSize=1e5*n,this.nextoutput=0,this.outputStream=t,this.streamCRC=0;}_get_next_block(){let e,t,r;const n=this.reader,i=n.pi();if("177245385090"===i)return !1;"314159265359"!==i&&d(o.NOT_BZIP_DATA),this.targetBlockCRC=n.read(32)>>>0,this.streamCRC=(this.targetBlockCRC^(this.streamCRC<<1|this.streamCRC>>>31))>>>0,n.read(1)&&d(o.OBSOLETE_INPUT);const a=n.read(24);a>this.dbufSize&&d(o.DATA_ERROR,"initial position out of bounds");let s=n.read(16),c=new Uint8Array(256),l=0;for(e=0;e<16;e++)if(s&1<<15-e){const i=16*e;for(r=n.read(16),t=0;t<16;t++)r&1<<15-t&&(c[l++]=i+t);}const f=n.read(3);(f<2||f>6)&&d(o.DATA_ERROR);const u=n.read(15);0===u&&d(o.DATA_ERROR);const g=new Uint8Array(256);for(e=0;e<f;e++)g[e]=e;const h=new Uint8Array(u);for(e=0;e<u;e++){for(t=0;n.read(1);t++)t>=f&&d(o.DATA_ERROR);h[e]=A(g,t);}let C,I=l+2,_=[];for(t=0;t<f;t++){const t=new Uint8Array(I),r=new Uint16Array(21);for(s=n.read(5),e=0;e<I;e++){for(;(s<1||s>20)&&d(o.DATA_ERROR),n.read(1);)n.read(1)?s--:s++;t[e]=s;}var m,B;for(m=B=t[0],e=1;e<I;e++)t[e]>B?B=t[e]:t[e]<m&&(m=t[e]);C={},_.push(C),C.permute=new Uint16Array(258),C.limit=new Uint32Array(22),C.base=new Uint32Array(21),C.minLen=m,C.maxLen=B;let i=0;for(e=m;e<=B;e++)for(r[e]=C.limit[e]=0,s=0;s<I;s++)t[s]===e&&(C.permute[i++]=s);for(e=0;e<I;e++)r[t[e]]++;for(i=s=0,e=m;e<B;e++)i+=r[e],C.limit[e]=i-1,i<<=1,s+=r[e],C.base[e+1]=i-s;C.limit[B+1]=Number.MAX_VALUE,C.limit[B]=i+r[B]-1,C.base[m]=0;}const p=new Uint32Array(256);for(e=0;e<256;e++)g[e]=e;let w,E=0,Q=0,y=0;const b=this.dbuf=new Uint32Array(this.dbufSize);for(I=0;;){for(I--||(I=49,y>=u&&d(o.DATA_ERROR),C=_[h[y++]]),e=C.minLen,t=n.read(e);e>C.maxLen&&d(o.DATA_ERROR),!(t<=C.limit[e]);e++)t=t<<1|n.read(1);t-=C.base[e],(t<0||t>=258)&&d(o.DATA_ERROR);const r=C.permute[t];if(0!==r&&1!==r){if(E)for(E=0,Q+s>this.dbufSize&&d(o.DATA_ERROR),w=c[g[0]],p[w]+=s;s--;)b[Q++]=w;if(r>l)break;Q>=this.dbufSize&&d(o.DATA_ERROR),e=r-1,w=A(g,e),w=c[w],p[w]++,b[Q++]=w;}else E||(E=1,s=0),s+=0===r?E:2*E,E<<=1;}for((a<0||a>=Q)&&d(o.DATA_ERROR),t=0,e=0;e<256;e++)r=t+p[e],p[e]=t,t=r;for(e=0;e<Q;e++)w=255&b[e],b[p[w]]|=e<<8,p[w]++;let D=0,S=0,k=0;return Q&&(D=b[a],S=255&D,D>>=8,k=-1),this.writePos=D,this.writeCurrent=S,this.writeCount=Q,this.writeRun=k,!0}_read_bunzip(e,t){let r,n,i;if(this.writeCount<0)return 0;let a=this.dbuf,s=this.writePos,A=this.writeCurrent,c=this.writeCount,l=(this.outputsize,this.writeRun);for(;c;){for(c--,n=A,s=a[s],A=255&s,s>>=8,3===l++?(r=A,i=n,A=-1):(r=1,i=A),this.blockCRC.updateCRCRun(i,r);r--;)this.outputStream.writeByte(i),this.nextoutput++;A!=n&&(l=0);}return this.writeCount=c,this.blockCRC.getCRC()!==this.targetBlockCRC&&d(o.DATA_ERROR,"Bad block CRC (got "+this.blockCRC.getCRC().toString(16)+" expected "+this.targetBlockCRC.toString(16)+")"),this.nextoutput}}const f=function(e){if("readByte"in e)return e;const t=new s.default;return t.pos=0,t.readByte=function(){return e[this.pos++]},t.seek=function(e){this.pos=e;},t.eof=function(){return this.pos>=e.length},t},u=function(e){const t=new s.default;let r=!0;if(e)if("number"==typeof e)t.buffer=new Uint8Array(e),r=!1;else {if("writeByte"in e)return e;t.buffer=e,r=!1;}else t.buffer=new Uint8Array(16384);return t.pos=0,t.writeByte=function(e){if(r&&this.pos>=this.buffer.length){const e=new Uint8Array(2*this.buffer.length);e.set(this.buffer),this.buffer=e;}this.buffer[this.pos++]=e;},t.getBuffer=function(){if(this.pos!==this.buffer.length){if(!r)throw new TypeError("outputsize does not match decoded input");const e=new Uint8Array(this.pos);e.set(this.buffer.slice(0,this.pos)),this.buffer=e;}return this.buffer},t._coerced=!0,t};t.default=l;},1064:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(e){this.blob=e,this.size=e.size;}async read(e,t=0){if(!e)return new Uint8Array(0);const r=t,n=r+e;return new Uint8Array(await this.blob.slice(r,n).arrayBuffer())}async readFile(e){const t="string"==typeof e?e:e?.encoding;if("utf8"===t)return this.blob.text();if(t)throw new Error(`unsupported encoding: ${t}`);return new Uint8Array(await this.blob.arrayBuffer())}async stat(){return {size:this.size}}async close(){}};},1307:function(e,t,r){var n;n=e=>(()=>{var t=[,e=>{e.exports="data:application/wasm;base64,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";},t=>{t.exports=e;}],r={};function n(e){var i=r[e];if(void 0!==i)return i.exports;var a=r[e]={exports:{}};return t[e](a,a.exports,n),a.exports}n.d=(e,t)=>{for(var r in t)n.o(t,r)&&!n.o(e,r)&&Object.defineProperty(e,r,{enumerable:!0,get:t[r]});},n.o=(e,t)=>Object.prototype.hasOwnProperty.call(e,t),n.r=e=>{"undefined"!=typeof Symbol&&Symbol.toStringTag&&Object.defineProperty(e,Symbol.toStringTag,{value:"Module"}),Object.defineProperty(e,"__esModule",{value:!0});};var i={};return (()=>{n.r(i),n.d(i,{XzReadableStream:()=>a});var e=n(1);const t=globalThis.ReadableStream||n(2).ReadableStream;class r{constructor(e){this.exports=e.exports,this.memory=this.exports.memory,this.ptr=this.exports.create_context(),this._refresh(),this.bufSize=this.mem32[0],this.inStart=this.mem32[1]-this.ptr,this.inEnd=this.inStart+this.bufSize,this.outStart=this.mem32[4]-this.ptr;}supplyInput(e){this._refresh(),this.mem8.subarray(this.inStart,this.inEnd).set(e,0),this.exports.supply_input(this.ptr,e.byteLength),this._refresh();}getNextOutput(){const e=this.exports.get_next_output(this.ptr);if(this._refresh(),0!==e&&1!==e)throw new Error(`get_next_output failed with error code ${e}`);return {outChunk:this.mem8.slice(this.outStart,this.outStart+this.mem32[5]),finished:1===e}}needsMoreInput(){return this.mem32[2]===this.mem32[3]}outputBufferIsFull(){return this.mem32[5]===this.bufSize}resetOutputBuffer(){this.outPos=this.mem32[5]=0;}dispose(){this.exports.destroy_context(this.ptr),this.exports=null;}_refresh(){this.memory.buffer!==this.mem8?.buffer&&(this.mem8=new Uint8Array(this.memory.buffer,this.ptr),this.mem32=new Uint32Array(this.memory.buffer,this.ptr));}}class a extends t{static _moduleInstancePromise;static _moduleInstance;static async _getModuleInstance(){const t=e.replace("data:application/wasm;base64,",""),r=Uint8Array.from(atob(t),(e=>e.charCodeAt(0))).buffer,n=await WebAssembly.instantiate(r,{});a._moduleInstance=n.instance;}constructor(e){let t,n=null;const i=e.getReader();super({async start(e){a._moduleInstance||await(a._moduleInstancePromise||(a._moduleInstancePromise=a._getModuleInstance())),t=new r(a._moduleInstance);},async pull(e){if(t.needsMoreInput()){if(null===n||0===n.byteLength){const{done:e,value:t}=await i.read();e||(n=t);}const e=Math.min(t.bufSize,n.byteLength);t.supplyInput(n.subarray(0,e)),n=n.subarray(e);}const r=t.getNextOutput();e.enqueue(r.outChunk),t.resetOutputBuffer(),r.finished&&(t.dispose(),e.close());},cancel:()=>(t.dispose(),i.cancel())});}}})(),i})(),e.exports=n(r(772));},1308:(e,t)=>{let r=[0,1996959894,3993919788,2567524794,124634137,1886057615,3915621685,2657392035,249268274,2044508324,3772115230,2547177864,162941995,2125561021,3887607047,2428444049,498536548,1789927666,4089016648,2227061214,450548861,1843258603,4107580753,2211677639,325883990,1684777152,4251122042,2321926636,335633487,1661365465,4195302755,2366115317,997073096,1281953886,3579855332,2724688242,1006888145,1258607687,3524101629,2768942443,901097722,1119000684,3686517206,2898065728,853044451,1172266101,3705015759,2882616665,651767980,1373503546,3369554304,3218104598,565507253,1454621731,3485111705,3099436303,671266974,1594198024,3322730930,2970347812,795835527,1483230225,3244367275,3060149565,1994146192,31158534,2563907772,4023717930,1907459465,112637215,2680153253,3904427059,2013776290,251722036,2517215374,3775830040,2137656763,141376813,2439277719,3865271297,1802195444,476864866,2238001368,4066508878,1812370925,453092731,2181625025,4111451223,1706088902,314042704,2344532202,4240017532,1658658271,366619977,2362670323,4224994405,1303535960,984961486,2747007092,3569037538,1256170817,1037604311,2765210733,3554079995,1131014506,879679996,2909243462,3663771856,1141124467,855842277,2852801631,3708648649,1342533948,654459306,3188396048,3373015174,1466479909,544179635,3110523913,3462522015,1591671054,702138776,2966460450,3352799412,1504918807,783551873,3082640443,3233442989,3988292384,2596254646,62317068,1957810842,3939845945,2647816111,81470997,1943803523,3814918930,2489596804,225274430,2053790376,3826175755,2466906013,167816743,2097651377,4027552580,2265490386,503444072,1762050814,4150417245,2154129355,426522225,1852507879,4275313526,2312317920,282753626,1742555852,4189708143,2394877945,397917763,1622183637,3604390888,2714866558,953729732,1340076626,3518719985,2797360999,1068828381,1219638859,3624741850,2936675148,906185462,1090812512,3747672003,2825379669,829329135,1181335161,3412177804,3160834842,628085408,1382605366,3423369109,3138078467,570562233,1426400815,3317316542,2998733608,733239954,1555261956,3268935591,3050360625,752459403,1541320221,2607071920,3965973030,1969922972,40735498,2617837225,3943577151,1913087877,83908371,2512341634,3803740692,2075208622,213261112,2463272603,3855990285,2094854071,198958881,2262029012,4057260610,1759359992,534414190,2176718541,4139329115,1873836001,414664567,2282248934,4279200368,1711684554,285281116,2405801727,4167216745,1634467795,376229701,2685067896,3608007406,1308918612,956543938,2808555105,3495958263,1231636301,1047427035,2932959818,3654703836,1088359270,936918e3,2847714899,3736837829,1202900863,817233897,3183342108,3401237130,1404277552,615818150,3134207493,3453421203,1423857449,601450431,3009837614,3294710456,1567103746,711928724,3020668471,3272380065,1510334235,755167117];"undefined"!=typeof Int32Array&&(r=new Int32Array(r)),t.A=(e,t)=>{let n=0===t?0:-1^t;for(let t=0;t<e.length;t++)n=r[255&(n^e[t])]^n>>>8;return -1^n};},1447:(e,t,r)=>{var n=r(9805),i=r(3269),a=r(4823),s=r(7293),A=r(1998),o=-2,c=12,d=30;function l(e){return (e>>>24&255)+(e>>>8&65280)+((65280&e)<<8)+((255&e)<<24)}function f(){this.mode=0,this.last=!1,this.wrap=0,this.havedict=!1,this.flags=0,this.dmax=0,this.check=0,this.total=0,this.head=null,this.wbits=0,this.wsize=0,this.whave=0,this.wnext=0,this.window=null,this.hold=0,this.bits=0,this.length=0,this.offset=0,this.extra=0,this.lencode=null,this.distcode=null,this.lenbits=0,this.distbits=0,this.ncode=0,this.nlen=0,this.ndist=0,this.have=0,this.next=null,this.lens=new n.Buf16(320),this.work=new n.Buf16(288),this.lendyn=null,this.distdyn=null,this.sane=0,this.back=0,this.was=0;}function u(e){var t;return e&&e.state?(t=e.state,e.total_in=e.total_out=t.total=0,e.msg="",t.wrap&&(e.adler=1&t.wrap),t.mode=1,t.last=0,t.havedict=0,t.dmax=32768,t.head=null,t.hold=0,t.bits=0,t.lencode=t.lendyn=new n.Buf32(852),t.distcode=t.distdyn=new n.Buf32(592),t.sane=1,t.back=-1,0):o}function g(e){var t;return e&&e.state?((t=e.state).wsize=0,t.whave=0,t.wnext=0,u(e)):o}function h(e,t){var r,n;return e&&e.state?(n=e.state,t<0?(r=0,t=-t):(r=1+(t>>4),t<48&&(t&=15)),t&&(t<8||t>15)?o:(null!==n.window&&n.wbits!==t&&(n.window=null),n.wrap=r,n.wbits=t,g(e))):o}function C(e,t){var r,n;return e?(n=new f,e.state=n,n.window=null,0!==(r=h(e,t))&&(e.state=null),r):o}var I,_,m=!0;function B(e){if(m){var t;for(I=new n.Buf32(512),_=new n.Buf32(32),t=0;t<144;)e.lens[t++]=8;for(;t<256;)e.lens[t++]=9;for(;t<280;)e.lens[t++]=7;for(;t<288;)e.lens[t++]=8;for(A(1,e.lens,0,288,I,0,e.work,{bits:9}),t=0;t<32;)e.lens[t++]=5;A(2,e.lens,0,32,_,0,e.work,{bits:5}),m=!1;}e.lencode=I,e.lenbits=9,e.distcode=_,e.distbits=5;}function p(e,t,r,i){var a,s=e.state;return null===s.window&&(s.wsize=1<<s.wbits,s.wnext=0,s.whave=0,s.window=new n.Buf8(s.wsize)),i>=s.wsize?(n.arraySet(s.window,t,r-s.wsize,s.wsize,0),s.wnext=0,s.whave=s.wsize):((a=s.wsize-s.wnext)>i&&(a=i),n.arraySet(s.window,t,r-i,a,s.wnext),(i-=a)?(n.arraySet(s.window,t,r-i,i,0),s.wnext=i,s.whave=s.wsize):(s.wnext+=a,s.wnext===s.wsize&&(s.wnext=0),s.whave<s.wsize&&(s.whave+=a))),0}t.inflateReset=g,t.inflateReset2=h,t.inflateResetKeep=u,t.inflateInit=function(e){return C(e,15)},t.inflateInit2=C,t.inflate=function(e,t){var r,f,u,g,h,C,I,_,m,w,E,Q,y,b,D,S,k,v,R,F,M,N,x,L,O=0,T=new n.Buf8(4),P=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15];if(!e||!e.state||!e.output||!e.input&&0!==e.avail_in)return o;(r=e.state).mode===c&&(r.mode=13),h=e.next_out,u=e.output,I=e.avail_out,g=e.next_in,f=e.input,C=e.avail_in,_=r.hold,m=r.bits,w=C,E=I,N=0;e:for(;;)switch(r.mode){case 1:if(0===r.wrap){r.mode=13;break}for(;m<16;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}if(2&r.wrap&&35615===_){r.check=0,T[0]=255&_,T[1]=_>>>8&255,r.check=a(r.check,T,2,0),_=0,m=0,r.mode=2;break}if(r.flags=0,r.head&&(r.head.done=!1),!(1&r.wrap)||(((255&_)<<8)+(_>>8))%31){e.msg="incorrect header check",r.mode=d;break}if(8!=(15&_)){e.msg="unknown compression method",r.mode=d;break}if(m-=4,M=8+(15&(_>>>=4)),0===r.wbits)r.wbits=M;else if(M>r.wbits){e.msg="invalid window size",r.mode=d;break}r.dmax=1<<M,e.adler=r.check=1,r.mode=512&_?10:c,_=0,m=0;break;case 2:for(;m<16;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}if(r.flags=_,8!=(255&r.flags)){e.msg="unknown compression method",r.mode=d;break}if(57344&r.flags){e.msg="unknown header flags set",r.mode=d;break}r.head&&(r.head.text=_>>8&1),512&r.flags&&(T[0]=255&_,T[1]=_>>>8&255,r.check=a(r.check,T,2,0)),_=0,m=0,r.mode=3;case 3:for(;m<32;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}r.head&&(r.head.time=_),512&r.flags&&(T[0]=255&_,T[1]=_>>>8&255,T[2]=_>>>16&255,T[3]=_>>>24&255,r.check=a(r.check,T,4,0)),_=0,m=0,r.mode=4;case 4:for(;m<16;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}r.head&&(r.head.xflags=255&_,r.head.os=_>>8),512&r.flags&&(T[0]=255&_,T[1]=_>>>8&255,r.check=a(r.check,T,2,0)),_=0,m=0,r.mode=5;case 5:if(1024&r.flags){for(;m<16;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}r.length=_,r.head&&(r.head.extra_len=_),512&r.flags&&(T[0]=255&_,T[1]=_>>>8&255,r.check=a(r.check,T,2,0)),_=0,m=0;}else r.head&&(r.head.extra=null);r.mode=6;case 6:if(1024&r.flags&&((Q=r.length)>C&&(Q=C),Q&&(r.head&&(M=r.head.extra_len-r.length,r.head.extra||(r.head.extra=new Array(r.head.extra_len)),n.arraySet(r.head.extra,f,g,Q,M)),512&r.flags&&(r.check=a(r.check,f,Q,g)),C-=Q,g+=Q,r.length-=Q),r.length))break e;r.length=0,r.mode=7;case 7:if(2048&r.flags){if(0===C)break e;Q=0;do{M=f[g+Q++],r.head&&M&&r.length<65536&&(r.head.name+=String.fromCharCode(M));}while(M&&Q<C);if(512&r.flags&&(r.check=a(r.check,f,Q,g)),C-=Q,g+=Q,M)break e}else r.head&&(r.head.name=null);r.length=0,r.mode=8;case 8:if(4096&r.flags){if(0===C)break e;Q=0;do{M=f[g+Q++],r.head&&M&&r.length<65536&&(r.head.comment+=String.fromCharCode(M));}while(M&&Q<C);if(512&r.flags&&(r.check=a(r.check,f,Q,g)),C-=Q,g+=Q,M)break e}else r.head&&(r.head.comment=null);r.mode=9;case 9:if(512&r.flags){for(;m<16;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}if(_!==(65535&r.check)){e.msg="header crc mismatch",r.mode=d;break}_=0,m=0;}r.head&&(r.head.hcrc=r.flags>>9&1,r.head.done=!0),e.adler=r.check=0,r.mode=c;break;case 10:for(;m<32;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}e.adler=r.check=l(_),_=0,m=0,r.mode=11;case 11:if(0===r.havedict)return e.next_out=h,e.avail_out=I,e.next_in=g,e.avail_in=C,r.hold=_,r.bits=m,2;e.adler=r.check=1,r.mode=c;case c:if(5===t||6===t)break e;case 13:if(r.last){_>>>=7&m,m-=7&m,r.mode=27;break}for(;m<3;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}switch(r.last=1&_,m-=1,3&(_>>>=1)){case 0:r.mode=14;break;case 1:if(B(r),r.mode=20,6===t){_>>>=2,m-=2;break e}break;case 2:r.mode=17;break;case 3:e.msg="invalid block type",r.mode=d;}_>>>=2,m-=2;break;case 14:for(_>>>=7&m,m-=7&m;m<32;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}if((65535&_)!=(_>>>16^65535)){e.msg="invalid stored block lengths",r.mode=d;break}if(r.length=65535&_,_=0,m=0,r.mode=15,6===t)break e;case 15:r.mode=16;case 16:if(Q=r.length){if(Q>C&&(Q=C),Q>I&&(Q=I),0===Q)break e;n.arraySet(u,f,g,Q,h),C-=Q,g+=Q,I-=Q,h+=Q,r.length-=Q;break}r.mode=c;break;case 17:for(;m<14;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}if(r.nlen=257+(31&_),_>>>=5,m-=5,r.ndist=1+(31&_),_>>>=5,m-=5,r.ncode=4+(15&_),_>>>=4,m-=4,r.nlen>286||r.ndist>30){e.msg="too many length or distance symbols",r.mode=d;break}r.have=0,r.mode=18;case 18:for(;r.have<r.ncode;){for(;m<3;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}r.lens[P[r.have++]]=7&_,_>>>=3,m-=3;}for(;r.have<19;)r.lens[P[r.have++]]=0;if(r.lencode=r.lendyn,r.lenbits=7,x={bits:r.lenbits},N=A(0,r.lens,0,19,r.lencode,0,r.work,x),r.lenbits=x.bits,N){e.msg="invalid code lengths set",r.mode=d;break}r.have=0,r.mode=19;case 19:for(;r.have<r.nlen+r.ndist;){for(;S=(O=r.lencode[_&(1<<r.lenbits)-1])>>>16&255,k=65535&O,!((D=O>>>24)<=m);){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}if(k<16)_>>>=D,m-=D,r.lens[r.have++]=k;else {if(16===k){for(L=D+2;m<L;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}if(_>>>=D,m-=D,0===r.have){e.msg="invalid bit length repeat",r.mode=d;break}M=r.lens[r.have-1],Q=3+(3&_),_>>>=2,m-=2;}else if(17===k){for(L=D+3;m<L;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}m-=D,M=0,Q=3+(7&(_>>>=D)),_>>>=3,m-=3;}else {for(L=D+7;m<L;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}m-=D,M=0,Q=11+(127&(_>>>=D)),_>>>=7,m-=7;}if(r.have+Q>r.nlen+r.ndist){e.msg="invalid bit length repeat",r.mode=d;break}for(;Q--;)r.lens[r.have++]=M;}}if(r.mode===d)break;if(0===r.lens[256]){e.msg="invalid code -- missing end-of-block",r.mode=d;break}if(r.lenbits=9,x={bits:r.lenbits},N=A(1,r.lens,0,r.nlen,r.lencode,0,r.work,x),r.lenbits=x.bits,N){e.msg="invalid literal/lengths set",r.mode=d;break}if(r.distbits=6,r.distcode=r.distdyn,x={bits:r.distbits},N=A(2,r.lens,r.nlen,r.ndist,r.distcode,0,r.work,x),r.distbits=x.bits,N){e.msg="invalid distances set",r.mode=d;break}if(r.mode=20,6===t)break e;case 20:r.mode=21;case 21:if(C>=6&&I>=258){e.next_out=h,e.avail_out=I,e.next_in=g,e.avail_in=C,r.hold=_,r.bits=m,s(e,E),h=e.next_out,u=e.output,I=e.avail_out,g=e.next_in,f=e.input,C=e.avail_in,_=r.hold,m=r.bits,r.mode===c&&(r.back=-1);break}for(r.back=0;S=(O=r.lencode[_&(1<<r.lenbits)-1])>>>16&255,k=65535&O,!((D=O>>>24)<=m);){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}if(S&&!(240&S)){for(v=D,R=S,F=k;S=(O=r.lencode[F+((_&(1<<v+R)-1)>>v)])>>>16&255,k=65535&O,!(v+(D=O>>>24)<=m);){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}_>>>=v,m-=v,r.back+=v;}if(_>>>=D,m-=D,r.back+=D,r.length=k,0===S){r.mode=26;break}if(32&S){r.back=-1,r.mode=c;break}if(64&S){e.msg="invalid literal/length code",r.mode=d;break}r.extra=15&S,r.mode=22;case 22:if(r.extra){for(L=r.extra;m<L;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}r.length+=_&(1<<r.extra)-1,_>>>=r.extra,m-=r.extra,r.back+=r.extra;}r.was=r.length,r.mode=23;case 23:for(;S=(O=r.distcode[_&(1<<r.distbits)-1])>>>16&255,k=65535&O,!((D=O>>>24)<=m);){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}if(!(240&S)){for(v=D,R=S,F=k;S=(O=r.distcode[F+((_&(1<<v+R)-1)>>v)])>>>16&255,k=65535&O,!(v+(D=O>>>24)<=m);){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}_>>>=v,m-=v,r.back+=v;}if(_>>>=D,m-=D,r.back+=D,64&S){e.msg="invalid distance code",r.mode=d;break}r.offset=k,r.extra=15&S,r.mode=24;case 24:if(r.extra){for(L=r.extra;m<L;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}r.offset+=_&(1<<r.extra)-1,_>>>=r.extra,m-=r.extra,r.back+=r.extra;}if(r.offset>r.dmax){e.msg="invalid distance too far back",r.mode=d;break}r.mode=25;case 25:if(0===I)break e;if(Q=E-I,r.offset>Q){if((Q=r.offset-Q)>r.whave&&r.sane){e.msg="invalid distance too far back",r.mode=d;break}Q>r.wnext?(Q-=r.wnext,y=r.wsize-Q):y=r.wnext-Q,Q>r.length&&(Q=r.length),b=r.window;}else b=u,y=h-r.offset,Q=r.length;Q>I&&(Q=I),I-=Q,r.length-=Q;do{u[h++]=b[y++];}while(--Q);0===r.length&&(r.mode=21);break;case 26:if(0===I)break e;u[h++]=r.length,I--,r.mode=21;break;case 27:if(r.wrap){for(;m<32;){if(0===C)break e;C--,_|=f[g++]<<m,m+=8;}if(E-=I,e.total_out+=E,r.total+=E,E&&(e.adler=r.check=r.flags?a(r.check,u,E,h-E):i(r.check,u,E,h-E)),E=I,(r.flags?_:l(_))!==r.check){e.msg="incorrect data check",r.mode=d;break}_=0,m=0;}r.mode=28;case 28:if(r.wrap&&r.flags){for(;m<32;){if(0===C)break e;C--,_+=f[g++]<<m,m+=8;}if(_!==(4294967295&r.total)){e.msg="incorrect length check",r.mode=d;break}_=0,m=0;}r.mode=29;case 29:N=1;break e;case d:N=-3;break e;case 31:return -4;default:return o}return e.next_out=h,e.avail_out=I,e.next_in=g,e.avail_in=C,r.hold=_,r.bits=m,(r.wsize||E!==e.avail_out&&r.mode<d&&(r.mode<27||4!==t))&&p(e,e.output,e.next_out,E-e.avail_out)?(r.mode=31,-4):(w-=e.avail_in,E-=e.avail_out,e.total_in+=w,e.total_out+=E,r.total+=E,r.wrap&&E&&(e.adler=r.check=r.flags?a(r.check,u,E,e.next_out-E):i(r.check,u,E,e.next_out-E)),e.data_type=r.bits+(r.last?64:0)+(r.mode===c?128:0)+(20===r.mode||15===r.mode?256:0),(0===w&&0===E||4===t)&&0===N&&(N=-5),N)},t.inflateEnd=function(e){if(!e||!e.state)return o;var t=e.state;return t.window&&(t.window=null),e.state=null,0},t.inflateGetHeader=function(e,t){var r;return e&&e.state&&2&(r=e.state).wrap?(r.head=t,t.done=!1,0):o},t.inflateSetDictionary=function(e,t){var r,n=t.length;return e&&e.state?0!==(r=e.state).wrap&&11!==r.mode?o:11===r.mode&&i(1,t,n,0)!==r.check?-3:p(e,t,n,n)?(r.mode=31,-4):(r.havedict=1,0):o},t.inflateInfo="pako inflate (from Nodeca project)";},1492:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(6761),s=r(6272);class A extends i.default{constructor(e,t){if(super(e,t),"int"!==this.dataType)throw new s.CramUnimplementedError(`${this.dataType} decoding not yet implemented by SUBEXP codec`)}decode(e,t,r,n){let i,s,A=0;for(;(0, a.getBits)(t.content,n.coreBlock,1);)A+=1;return 0===A?(i=this.parameters.K,s=(0, a.getBits)(t.content,n.coreBlock,i)):(i=A+this.parameters.K-1,s=1<<i|(0, a.getBits)(t.content,n.coreBlock,i)),s-this.parameters.offset}}t.default=A;},1558:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.default=function(e,t,r,n){let A=e.getInt(),o=e.getInt(),c=e.getInt(),d=e.getInt();const l=n.remaining(),f=-4&l;for(let i=0;i<f;i+=4){const l=t.R[s.default.get(A,a.TF_SHIFT)],f=t.R[s.default.get(o,a.TF_SHIFT)],u=t.R[s.default.get(c,a.TF_SHIFT)],g=t.R[s.default.get(d,a.TF_SHIFT)];n.putAt(i,l),n.putAt(i+1,f),n.putAt(i+2,u),n.putAt(i+3,g),A=s.default.advanceSymbolStep(A,r[255&l],a.TF_SHIFT),o=s.default.advanceSymbolStep(o,r[255&f],a.TF_SHIFT),c=s.default.advanceSymbolStep(c,r[255&u],a.TF_SHIFT),d=s.default.advanceSymbolStep(d,r[255&g],a.TF_SHIFT),A=s.default.renormalize(A,e),o=s.default.renormalize(o,e),c=s.default.renormalize(c,e),d=s.default.renormalize(d,e);}let u;switch(n.setPosition(f),3&l){case 0:break;case 1:u=t.R[s.default.get(A,a.TF_SHIFT)],s.default.advanceSymbol(A,e,r[255&u],a.TF_SHIFT),n.put(u);break;case 2:u=t.R[s.default.get(A,a.TF_SHIFT)],s.default.advanceSymbol(A,e,r[255&u],a.TF_SHIFT),n.put(u),u=t.R[s.default.get(o,a.TF_SHIFT)],s.default.advanceSymbol(o,e,r[255&u],a.TF_SHIFT),n.put(u);break;case 3:u=t.R[s.default.get(A,a.TF_SHIFT)],s.default.advanceSymbol(A,e,r[255&u],a.TF_SHIFT),n.put(u),u=t.R[s.default.get(o,a.TF_SHIFT)],s.default.advanceSymbol(o,e,r[255&u],a.TF_SHIFT),n.put(u),u=t.R[s.default.get(c,a.TF_SHIFT)],s.default.advanceSymbol(c,e,r[255&u],a.TF_SHIFT),n.put(u);break;default:throw new i.CramMalformedError("invalid output size encountered during rANS decoding")}n.setPosition(0);};const i=r(6272),a=r(7151),s=n(r(9301));},1609:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.instantiateCodec=function e(t,r){const n=(i="ignore"===r?0:t.codecId,f[i]);var i;if(!n)throw new l.CramUnimplementedError(`no codec implemented for codec ID ${t.codecId}`);return new n(t.parameters,r,e)};const i=n(r(807)),a=n(r(7934)),s=n(r(8006)),A=n(r(8930)),o=n(r(632)),c=n(r(4056)),d=n(r(1492)),l=r(6272),f={1:A.default,3:c.default,4:a.default,5:s.default,6:i.default,7:d.default,9:o.default};},1668:(e,t,r)=>{var n={};(0, r(9805).assign)(n,r(3303),r(7083),r(9681)),e.exports=n;},1739:function(e,t,r){var n,i=this&&this.__createBinding||(Object.create?function(e,t,r,n){void 0===n&&(n=r);var i=Object.getOwnPropertyDescriptor(t,r);i&&!("get"in i?!t.__esModule:i.writable||i.configurable)||(i={enumerable:!0,get:function(){return t[r]}}),Object.defineProperty(e,n,i);}:function(e,t,r,n){void 0===n&&(n=r),e[n]=t[r];}),a=this&&this.__setModuleDefault||(Object.create?function(e,t){Object.defineProperty(e,"default",{enumerable:!0,value:t});}:function(e,t){e.default=t;}),s=this&&this.__importStar||(n=function(e){return n=Object.getOwnPropertyNames||function(e){var t=[];for(var r in e)Object.prototype.hasOwnProperty.call(e,r)&&(t[t.length]=r);return t},n(e)},function(e){if(e&&e.__esModule)return e;var t={};if(null!=e)for(var r=n(e),s=0;s<r.length;s++)"default"!==r[s]&&i(t,e,r[s]);return a(t,e),t}),A=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.decode=function(e,t,r){(e=new d.default(e)).ReadUint32();const n=e.ReadUint32(),i=e.ReadByte(),a=function(e,t,r,n){let i=-1;const a=new Array(256);for(;!e.EOF();){const t=e.ReadByte(),s=128&t,A=64&t,c=63&t;if(s&&(i++,a[i]=new Array(13)),c!=u&&s){const e=new Array(n-1).fill(w);a[i][u]=new d.default((0, o.concatUint8Array)([new Uint8Array(c),e]));}if(A){const t=e.ReadByte(),r=e.ReadByte();a[i][c]=new d.default(a[t][r].buf);}else {const t=e.ReadUint7(),n=e.ReadData(t);a[i][c]=r?f.decode(n):l.decode(n),a[i][c]=new d.default(a[i][c]);}}return a}(e,0,i,n),s=new Array(n),A=new Array(n);let c="";void 0===r&&(r="\n");for(let e=0;e<n;e++)c+=y(a,s,A,e)+r;return c};const o=r(6951),c=A(r(9505)),d=A(r(3088)),l=s(r(9313)),f=new c.default,u=0,g=1,h=2,C=3,I=4,_=5,m=7,B=8,p=9,w=10,E=12;function Q(e,t){let r=e+"";for(;r.length<t;)r="0"+r;return r}function y(e,t,r,n){let i=e[0][u].ReadByte();const a=n-e[0][i].ReadUint32();if(i==_)return t[n]=t[a],r[n]=r[a],t[n];let s=1;t[n]="",r[n]=new Array(256);do{switch(i=e[s][u].ReadByte(),i){case h:r[n][s]=e[s][h].ReadChar();break;case g:r[n][s]=e[s][g].ReadString();break;case m:r[n][s]=e[s][m].ReadUint32();break;case C:var A=e[s][C].ReadUint32(),o=e[s][I].ReadByte();r[n][s]=Q(A,o);break;case B:r[n][s]=(0|r[a][s])+e[s][B].ReadByte();break;case p:A=(0|r[a][s])+e[s][p].ReadByte(),o=r[a][s].length,r[n][s]=Q(A,o);break;case w:r[n][s]=r[a][s];break;default:r[n][s]="";}t[n]+=r[n][s++];}while(i!=E);return t[n]}},1996:(e,t,r)=>{var n=r(9805),i=!0,a=!0;try{String.fromCharCode.apply(null,[0]);}catch(e){i=!1;}try{String.fromCharCode.apply(null,new Uint8Array(1));}catch(e){a=!1;}for(var s=new n.Buf8(256),A=0;A<256;A++)s[A]=A>=252?6:A>=248?5:A>=240?4:A>=224?3:A>=192?2:1;function o(e,t){if(t<65534&&(e.subarray&&a||!e.subarray&&i))return String.fromCharCode.apply(null,n.shrinkBuf(e,t));for(var r="",s=0;s<t;s++)r+=String.fromCharCode(e[s]);return r}s[254]=s[254]=1,t.string2buf=function(e){var t,r,i,a,s,A=e.length,o=0;for(a=0;a<A;a++)55296==(64512&(r=e.charCodeAt(a)))&&a+1<A&&56320==(64512&(i=e.charCodeAt(a+1)))&&(r=65536+(r-55296<<10)+(i-56320),a++),o+=r<128?1:r<2048?2:r<65536?3:4;for(t=new n.Buf8(o),s=0,a=0;s<o;a++)55296==(64512&(r=e.charCodeAt(a)))&&a+1<A&&56320==(64512&(i=e.charCodeAt(a+1)))&&(r=65536+(r-55296<<10)+(i-56320),a++),r<128?t[s++]=r:r<2048?(t[s++]=192|r>>>6,t[s++]=128|63&r):r<65536?(t[s++]=224|r>>>12,t[s++]=128|r>>>6&63,t[s++]=128|63&r):(t[s++]=240|r>>>18,t[s++]=128|r>>>12&63,t[s++]=128|r>>>6&63,t[s++]=128|63&r);return t},t.buf2binstring=function(e){return o(e,e.length)},t.binstring2buf=function(e){for(var t=new n.Buf8(e.length),r=0,i=t.length;r<i;r++)t[r]=e.charCodeAt(r);return t},t.buf2string=function(e,t){var r,n,i,a,A=t||e.length,c=new Array(2*A);for(n=0,r=0;r<A;)if((i=e[r++])<128)c[n++]=i;else if((a=s[i])>4)c[n++]=65533,r+=a-1;else {for(i&=2===a?31:3===a?15:7;a>1&&r<A;)i=i<<6|63&e[r++],a--;a>1?c[n++]=65533:i<65536?c[n++]=i:(i-=65536,c[n++]=55296|i>>10&1023,c[n++]=56320|1023&i);}return o(c,n)},t.utf8border=function(e,t){var r;for((t=t||e.length)>e.length&&(t=e.length),r=t-1;r>=0&&128==(192&e[r]);)r--;return r<0||0===r?t:r+s[e[r]]>t?r:t};},1998:(e,t,r)=>{var n=r(9805),i=[3,4,5,6,7,8,9,10,11,13,15,17,19,23,27,31,35,43,51,59,67,83,99,115,131,163,195,227,258,0,0],a=[16,16,16,16,16,16,16,16,17,17,17,17,18,18,18,18,19,19,19,19,20,20,20,20,21,21,21,21,16,72,78],s=[1,2,3,4,5,7,9,13,17,25,33,49,65,97,129,193,257,385,513,769,1025,1537,2049,3073,4097,6145,8193,12289,16385,24577,0,0],A=[16,16,16,16,17,17,18,18,19,19,20,20,21,21,22,22,23,23,24,24,25,25,26,26,27,27,28,28,29,29,64,64];e.exports=function(e,t,r,o,c,d,l,f){var u,g,h,C,I,_,m,B,p,w=f.bits,E=0,Q=0,y=0,b=0,D=0,S=0,k=0,v=0,R=0,F=0,M=null,N=0,x=new n.Buf16(16),L=new n.Buf16(16),O=null,T=0;for(E=0;E<=15;E++)x[E]=0;for(Q=0;Q<o;Q++)x[t[r+Q]]++;for(D=w,b=15;b>=1&&0===x[b];b--);if(D>b&&(D=b),0===b)return c[d++]=20971520,c[d++]=20971520,f.bits=1,0;for(y=1;y<b&&0===x[y];y++);for(D<y&&(D=y),v=1,E=1;E<=15;E++)if(v<<=1,(v-=x[E])<0)return -1;if(v>0&&(0===e||1!==b))return -1;for(L[1]=0,E=1;E<15;E++)L[E+1]=L[E]+x[E];for(Q=0;Q<o;Q++)0!==t[r+Q]&&(l[L[t[r+Q]]++]=Q);if(0===e?(M=O=l,_=19):1===e?(M=i,N-=257,O=a,T-=257,_=256):(M=s,O=A,_=-1),F=0,Q=0,E=y,I=d,S=D,k=0,h=-1,C=(R=1<<D)-1,1===e&&R>852||2===e&&R>592)return 1;for(;;){m=E-k,l[Q]<_?(B=0,p=l[Q]):l[Q]>_?(B=O[T+l[Q]],p=M[N+l[Q]]):(B=96,p=0),u=1<<E-k,y=g=1<<S;do{c[I+(F>>k)+(g-=u)]=m<<24|B<<16|p;}while(0!==g);for(u=1<<E-1;F&u;)u>>=1;if(0!==u?(F&=u-1,F+=u):F=0,Q++,0===--x[E]){if(E===b)break;E=t[r+l[Q]];}if(E>D&&(F&C)!==h){for(0===k&&(k=D),I+=y,v=1<<(S=E-k);S+k<b&&!((v-=x[S+k])<=0);)S++,v<<=1;if(R+=1<<S,1===e&&R>852||2===e&&R>592)return 1;c[h=F&C]=D<<24|S<<16|I-d;}}return 0!==F&&(c[I+F]=E-k<<24|64<<16),f.bits=D,0};},2151:e=>{var t={utf8:{stringToBytes:function(e){return t.bin.stringToBytes(unescape(encodeURIComponent(e)))},bytesToString:function(e){return decodeURIComponent(escape(t.bin.bytesToString(e)))}},bin:{stringToBytes:function(e){for(var t=[],r=0;r<e.length;r++)t.push(255&e.charCodeAt(r));return t},bytesToString:function(e){for(var t=[],r=0;r<e.length;r++)t.push(String.fromCharCode(e[r]));return t.join("")}}};e.exports=t;},2169:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.unzip=function(e){return (0, n.inflate)(e)};const n=r(1668);},2324:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(e=256){this.total_freq=e,this.max_sym=e-1,this.S=[],this.F=[];for(let e=0;e<=this.max_sym;e++)this.S[e]=e,this.F[e]=1;}ModelDecode(e,t){const r=t.RangeGetFrequency(this.total_freq);let n=0,i=0;for(;n+this.F[i]<=r;)n+=this.F[i++];t.RangeDecode(e,n,this.F[i],this.total_freq),this.F[i]+=16,this.total_freq+=16,this.total_freq>65519&&this.ModelRenormalise();const a=this.S[i];if(i>0&&this.F[i]>this.F[i-1]){let e=this.F[i];this.F[i]=this.F[i-1],this.F[i-1]=e,e=this.S[i],this.S[i]=this.S[i-1],this.S[i-1]=e;}return a}ModelRenormalise(){this.total_freq=0;for(let e=0;e<=this.max_sym;e++)this.F[e]-=Math.floor(this.F[e]/2),this.total_freq+=this.F[e];}ModelEncode(e,t,r){let n=0;for(var i=0;this.S[i]!=r;i++)n+=this.F[i];if(t.RangeEncode(e,n,this.F[i],this.total_freq),this.F[i]+=16,this.total_freq+=16,this.total_freq>65519&&this.ModelRenormalise(),r=this.S[i],i>0&&this.F[i]>this.F[i-1]){let e=this.F[i];this.F[i]=this.F[i-1],this.F[i-1]=e,e=this.S[i],this.S[i]=this.S[i-1],this.S[i-1]=e;}}};},2549:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.TWO_PWR_56_DBL=t.TWO_PWR_24_DBL=t.TWO_PWR_64_DBL=t.TWO_PWR_32_DBL=t.TWO_PWR_16_DBL=void 0,t.itf8Size=function(e){return -128&e?-16384&e?-2097152&e?-268435456&e?5:4:3:2:1},t.parseItf8=function(e,t){let r=t;const n=e[r];let i;return n<128?(i=n,r+=1):n<192?(i=(63&n)<<8|e[r+1],r+=2):n<224?(i=(31&n)<<16|e[r+1]<<8|e[r+2],r+=3):n<240?(i=(15&n)<<24|e[r+1]<<16|e[r+2]<<8|e[r+3],r+=4):(i=(15&n)<<28|e[r+1]<<20|e[r+2]<<12|e[r+3]<<4|15&e[r+4],r+=5),[i,r-t]},t.parseLtf8=function(e,r){let n=r;const i=e[n];let a;return i<128?(a=i,n+=1):i<192?(a=16383&(i<<8|e[n+1]),n+=2):i<224?(a=(63&i)<<16|e[n+1]<<8|e[n+2],n+=3):i<240?(a=(31&i)<<24|e[n+1]<<16|e[n+2]<<8|e[n+3],n+=4):i<248?(a=(15&e[n])*t.TWO_PWR_32_DBL+(e[n+1]<<24|e[n+2]<<16|e[n+3]<<8|e[n+4]),n+=5):i<252?(a=((7&e[n])<<8|e[n+1])*t.TWO_PWR_32_DBL+(e[n+2]<<24|e[n+3]<<16|e[n+4]<<8|e[n+5]),n+=6):i<254?(a=((3&e[n])<<16|e[n+1]<<8|e[n+2])*t.TWO_PWR_32_DBL+(e[n+3]<<24|e[n+4]<<16|e[n+5]<<8|e[n+6]),n+=7):i<255?(a=(e[n+1]<<24|e[n+2]<<16|e[n+3]<<8|e[n+4])*t.TWO_PWR_32_DBL+(e[n+5]<<24|e[n+6]<<16|e[n+7]<<8|e[n+8]),n+=8):(a=e[n+1]*t.TWO_PWR_56_DBL+(e[n+2]<<24|e[n+3]<<16|e[n+4]<<8|e[n+5])*t.TWO_PWR_32_DBL+(e[n+6]<<24|e[n+7]<<16|e[n+8]<<8|e[n+9]),n+=9),[a,n-r]},t.parseItem=function(e,t,r=0,n=0){const{offset:i,value:a}=t(e,r);return {...a,_endPosition:i+n,_size:i-r}},t.tinyMemoize=function(e,t){const r=e.prototype[t],n=`_memo_${t}`;e.prototype[t]=function(){if(!(n in this)){const e=r.call(this);this[n]=e,Promise.resolve(e).catch((()=>{delete this[n];}));}return this[n]};},t.sequenceMD5=function(e){return (0, i.default)(e.toUpperCase().replaceAll(/[^\u0021-\u007e]/g,""))};const i=n(r(3503));t.TWO_PWR_16_DBL=65536,t.TWO_PWR_32_DBL=t.TWO_PWR_16_DBL*t.TWO_PWR_16_DBL,t.TWO_PWR_64_DBL=t.TWO_PWR_32_DBL*t.TWO_PWR_32_DBL,t.TWO_PWR_24_DBL=1<<24,t.TWO_PWR_56_DBL=t.TWO_PWR_24_DBL*t.TWO_PWR_32_DBL;},2616:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0});const n=r(9846);t.default=class{constructor(e,t={}){this.filename=e;}async read(e,t=0){const r=new Uint8Array(e),i=await(0, n.open)(this.filename,"r"),a=await i.read(r,0,e,t);return await i.close(),a.buffer.subarray(0,a.bytesRead)}async readFile(e){const t=await(0, n.readFile)(this.filename,e);return "string"==typeof t?t:new Uint8Array(t)}async stat(){return (0, n.stat)(this.filename)}async close(){}};},2660:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.decode=function(e,t){return function(e,t){const r=e.ReadUint7(),n=function(e){const t={max_sym:0};if(5!=e.ReadByte())return void console.error("Invalid FQZComp version number");const r=e.ReadByte(),n=r&h?e.ReadByte():1;let i=r.nparam>1?r.nparam-1:0;const a=new Array(256);if(r&C)i=e.ReadByte(),A(e,a,256);else {for(var s=0;s<n;s++)a[s]=s;for(;s<256;s++)a[s]=n-1;}t.do_rev=r&I,t.stab=a,t.max_sel=i,t.params=new Array(t.nparam);for(let r=0;r<n;r++)t.params[r]=m(e),t.max_sym<t.params[r].max_sym&&(t.max_sym=t.params[r].max_sym);return t}(e);if(!n)return;var s=n.params;const o=new Array(t.length),c=function(e){const t={};t.qual=new Array(65536);for(var r=0;r<65536;r++)t.qual[r]=new a.default(e.max_sym+1);for(t.len=new Array(4),r=0;r<4;r++)t.len[r]=new a.default(256);return t.rev=new a.default(2),t.dup=new a.default(2),e.max_sel>0&&(t.sel=new a.default(e.max_sel+1)),t}(n),d=new i.default(e);d.RangeStartDecode(e);const l=new Uint8Array(r),f={qctx:0,prevq:0,delta:0,p:0,s:0,x:0,len:0,is_dup:0,rec:0};let u=0;for(;u<r;){if(0==f.p){if(B(e,d,n,c,f,o),f.is_dup>0&&c.dup.ModelDecode(e,d)){for(let e=0;e<len;e++)l[u+e]=l[u+e-f.len];u+=f.len,f.p=0;continue}t.push(f.len);var g=(s=n.params[f.x]).context;}const r=c.qual[g].ModelDecode(e,d);l[u++]=s.qmap[r],g=_(s,f,r);}return n.do_rev&&function(e,t,r,n){let i=0,a=0;for(;a<t;){if(r[i]){let t=0,r=n[i]-1;for(;t<r;){const n=e[a+t];e[a+t]=e[a+r],e[a+r]=n,t++,r--;}}a+=n[i++];}}(l,r,o,t),l}(new s.default(e),t)};const i=n(r(4652)),a=n(r(2324)),s=n(r(3088));function A(e,t,r){let n=0,i=0,a=-1;const s=new Array(1024);for(;i<r;){const t=e.ReadByte();if(s[n++]=t,i+=t,t==a){let r=e.ReadByte();for(i+=t*r;r--;)s[n++]=t;}a=t;}let A=0;for(n=0,i=0;i<r;){let e=0;do{var o=s[n++];e+=o;}while(255==o);for(;e--;)t[i++]=A;A++;}}const o=2,c=4,d=8,l=16,f=32,u=64,g=128,h=1,C=2,I=4;function _(e,t,r){let n=e.context;return t.qctx=(t.qctx<<e.qshift)+e.qtab[r],n+=(t.qctx&(1<<e.qbits)-1)<<e.qloc,e.do_pos&&(n+=e.ptab[Math.min(t.p,1023)]<<e.ploc),e.do_delta&&(n+=e.dtab[Math.min(t.delta,255)]<<e.dloc,t.delta+=t.prevq!=r?1:0,t.prevq=r),e.do_sel&&(n+=t.s<<e.sloc),t.p--,65535&n}function m(e){const t={};t.context=e.ReadUint16(),t.pflags=e.ReadByte(),t.do_dedup=t.pflags&o,t.fixed_len=t.pflags&c,t.do_sel=t.pflags&d,t.do_qmap=t.pflags&l,t.do_pos=t.pflags&f,t.do_delta=t.pflags&u,t.do_qtab=t.pflags&g,t.max_sym=e.ReadByte();let r=e.ReadByte();if(t.qbits=r>>4,t.qshift=15&r,r=e.ReadByte(),t.qloc=r>>4,t.sloc=15&r,r=e.ReadByte(),t.ploc=r>>4,t.dloc=15&r,t.qmap=new Array(256),t.pflags&l)for(var n=0;n<t.max_sym;n++)t.qmap[n]=e.ReadByte();else for(n=0;n<256;n++)t.qmap[n]=n;if(t.qtab=new Array(1024),t.qbits>0&&t.pflags&g)A(e,t.qtab,256);else for(n=0;n<256;n++)t.qtab[n]=n;return t.ptab=new Array(1024),t.pflags&f&&A(e,t.ptab,1024),t.dtab=new Array(256),t.pflags&u&&A(e,t.dtab,256),t}function B(e,t,r,n,i,a){i.s=r.max_sel>0?n.sel.ModelDecode(e,t):0,i.x=r.stab[i.s];const s=r.params[i.x];if(s.fixed_len>=0){var A=n.len[0].ModelDecode(e,t);A|=n.len[1].ModelDecode(e,t)<<8,A|=n.len[2].ModelDecode(e,t)<<16,A|=n.len[3].ModelDecode(e,t)<<24,s.fixed_len>0&&(s.fixed_len=-A);}else A=-s.fixed_len;i.len=A,r.do_rev&&(a[i.rec]=n.rev.ModelDecode(e,t)),i.is_dup=0,s.pflags&o&&n.dup.ModelDecode(e,t)&&(i.is_dup=1),i.p=A,i.delta=0,i.qctx=0,i.prevq=0,i.rec++;}},2670:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.default=function(e,t,r=0){if(0===e.length)return t.fill(0),t;const n=new d(e,r),l=n.get();if(0!==l&&1!==l)throw new i.CramMalformedError(`Invalid rANS order ${l}`);if(n.getInt()!==n.remaining()-c)throw new i.CramMalformedError("Incorrect input length.");const f=n.getInt(),u=new d(t||new Uint8Array(f));if(u.length<f)throw new i.CramMalformedError(`Output buffer too small to fit ${f} bytes.`);switch(l){case 0:return function(e,t){const r=new A.default.AriDecoder,n=new Array(256);for(let e=0;e<n.length;e+=1)n[e]=new A.default.DecodingSymbol;return (0, o.readStatsO0)(e,r,n),(0, a.default)(e,r,n,t),t}(n,u);case 1:return function(e,t){const r=new Array(256);for(let e=0;e<r.length;e+=1)r[e]=new A.default.AriDecoder;const n=new Array(256);for(let e=0;e<n.length;e+=1){n[e]=new Array(256);for(let t=0;t<n[e].length;t+=1)n[e][t]=new A.default.DecodingSymbol;}return (0, o.readStatsO1)(e,r,n),(0, s.default)(e,t,r,n),t}(n,u);default:throw new i.CramMalformedError(`Invalid rANS order: ${l}`)}};const i=r(6272),a=n(r(1558)),s=n(r(2867)),A=n(r(9301)),o=r(6268),c=4;class d{constructor(e,t=0){this._buffer=e,this._dataView=new DataView(e.buffer),this._position=t,this.length=e.length;}get(){const e=this._buffer[this._position];return this._position+=1,e}getByte(){return this.get()}getByteAt(e){return this._buffer[e]}position(){return this._position}put(e){return this._buffer[this._position]=e,this._position+=1,e}putAt(e,t){return this._buffer[e]=t,t}setPosition(e){return this._position=e,e}getInt(){const e=this._dataView.getInt32(this._position,!0);return this._position+=4,e}remaining(){return this._buffer.length-this._position}}},2845:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=r(6272),a=n(r(500)),s=r(2549),A=n(r(8700)),o=r(7580);class c{constructor(e,t){this.file=e,this.filePosition=t;}getHeader(){return this._readContainerHeader(this.filePosition)}async getCompressionHeaderBlock(){if(!(await this.getHeader()).numRecords)return null;const{majorVersion:e}=await this.file.getDefinition(),t=(0, o.getSectionParsers)(e),r=await this.getFirstBlock();if("COMPRESSION_HEADER"!==r.contentType)throw new i.CramMalformedError(`invalid content type ${r.contentType} in compression header block`);const n=(0, s.parseItem)(r.content,t.cramCompressionHeader.parser,0,r.contentPosition);return {...r,parsedContent:n}}async getFirstBlock(){const e=await this.getHeader();return this.file.readBlock(e._endPosition)}async getCompressionScheme(){const e=await this.getCompressionHeaderBlock();if(e)return new A.default(e.parsedContent)}getSlice(e,t){return new a.default(this,e,t)}async _readContainerHeader(e){const{majorVersion:t}=await this.file.getDefinition(),r=(0, o.getSectionParsers)(t),{cramContainerHeader1:n,cramContainerHeader2:i}=r,a=await this.file.read(n.maxLength,e),A=(0, s.parseItem)(a,n.parser),c=(0, s.itf8Size)(A.numLandmarks),d=await this.file.read(i.maxLength(A.numLandmarks),e+A._size-c),l=(0, s.parseItem)(d,i.parser);return this.file.validateChecksums&&void 0!==l.crc32&&await this.file.checkCrc32(e,A._size+l._size-c-4,l.crc32,`container header beginning at position ${e}`),{...A,...l,_size:A._size+l._size-c,_endPosition:A._size+l._size-c+e}}}t.default=c,"getHeader getCompressionHeaderBlock getCompressionScheme".split(" ").forEach((e=>{(0, s.tinyMemoize)(c,e);}));},2867:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.default=function(e,t,r,n){const s=t.remaining();let A=e.getInt(),o=e.getInt(),c=e.getInt(),d=e.getInt();const l=s>>2;let f=0,u=l,g=2*l,h=3*l,C=0,I=0,_=0,m=0;for(;f<l;f+=1,u+=1,g+=1,h+=1){const s=255&r[C].R[a.default.get(A,i.TF_SHIFT)],l=255&r[I].R[a.default.get(o,i.TF_SHIFT)],B=255&r[_].R[a.default.get(c,i.TF_SHIFT)],p=255&r[m].R[a.default.get(d,i.TF_SHIFT)];t.putAt(f,s),t.putAt(u,l),t.putAt(g,B),t.putAt(h,p),A=a.default.advanceSymbolStep(A,n[C][s],i.TF_SHIFT),o=a.default.advanceSymbolStep(o,n[I][l],i.TF_SHIFT),c=a.default.advanceSymbolStep(c,n[_][B],i.TF_SHIFT),d=a.default.advanceSymbolStep(d,n[m][p],i.TF_SHIFT),A=a.default.renormalize(A,e),o=a.default.renormalize(o,e),c=a.default.renormalize(c,e),d=a.default.renormalize(d,e),C=s,I=l,_=B,m=p;}for(;h<s;h+=1){const s=255&r[m].R[a.default.get(d,i.TF_SHIFT)];t.putAt(h,s),d=a.default.advanceSymbol(d,e,n[m][s],i.TF_SHIFT),m=s;}};const i=r(7151),a=n(r(9301));},3088:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(e,t=0,r=0){0!==r?(this.buf=new Uint8Array(r),this.length=r):(this.buf=e,this.length=e.length),this.dataView=new DataView(this.buf.buffer),this.pos=t;}EOF(){return this.pos>=this.length}ReadData(e){const t=this.buf.slice(this.pos,this.pos+e);return this.pos+=e,t}ReadByte(){const e=this.buf[this.pos];return this.pos++,e}ReadChar(){const e=this.buf[this.pos];return this.pos++,String.fromCharCode(e)}ReadUint16(){let e=this.ReadByte();return e|=this.ReadByte()<<8,e}ReadUint32(){const e=this.dataView.getInt32(this.pos,!0);return this.pos+=4,e}ReadString(){let e,t="";do{e=this.buf[this.pos++],e&&(t+=String.fromCharCode(e));}while(e);return t}ReadUint7(){let e,t=0;do{e=this.ReadByte(),t=t<<7|127&e;}while(128&e);return t}ReadITF8(){let e=this.buf[this.pos];return this.pos++,e>=240?(e=(15&e)<<28,e+=(this.buf[this.pos+0]<<20)+(this.buf[this.pos+1]<<12)+(this.buf[this.pos+2]<<4)+(this.buf[this.pos+3]>>4),this.pos+=4):e>=224?(e=(15&e)<<24,e+=(this.buf[this.pos+0]<<16)+(this.buf[this.pos+1]<<8)+(0|this.buf[this.pos+2]),this.pos+=3):e>=192?(e=(31&e)<<16,e+=(this.buf[this.pos+0]<<8)+(0|this.buf[this.pos+1]),this.pos+=2):e>=128&&(e=(63&e)<<8,e+=this.buf[this.pos],this.pos++),e}};},3269:e=>{e.exports=function(e,t,r,n){for(var i=65535&e,a=e>>>16&65535,s=0;0!==r;){r-=s=r>2e3?2e3:r;do{a=a+(i=i+t[n++]|0)|0;}while(--s);i%=65521,a%=65521;}return i|a<<16};},3303:(e,t,r)=>{var n=r(8411),i=r(9805),a=r(1996),s=r(4674),A=r(4442),o=Object.prototype.toString;function c(e){if(!(this instanceof c))return new c(e);this.options=i.assign({level:-1,method:8,chunkSize:16384,windowBits:15,memLevel:8,strategy:0,to:""},e||{});var t=this.options;t.raw&&t.windowBits>0?t.windowBits=-t.windowBits:t.gzip&&t.windowBits>0&&t.windowBits<16&&(t.windowBits+=16),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new A,this.strm.avail_out=0;var r=n.deflateInit2(this.strm,t.level,t.method,t.windowBits,t.memLevel,t.strategy);if(0!==r)throw new Error(s[r]);if(t.header&&n.deflateSetHeader(this.strm,t.header),t.dictionary){var d;if(d="string"==typeof t.dictionary?a.string2buf(t.dictionary):"[object ArrayBuffer]"===o.call(t.dictionary)?new Uint8Array(t.dictionary):t.dictionary,0!==(r=n.deflateSetDictionary(this.strm,d)))throw new Error(s[r]);this._dict_set=!0;}}function d(e,t){var r=new c(t);if(r.push(e,!0),r.err)throw r.msg||s[r.err];return r.result}c.prototype.push=function(e,t){var r,s,A=this.strm,c=this.options.chunkSize;if(this.ended)return !1;s=t===~~t?t:!0===t?4:0,"string"==typeof e?A.input=a.string2buf(e):"[object ArrayBuffer]"===o.call(e)?A.input=new Uint8Array(e):A.input=e,A.next_in=0,A.avail_in=A.input.length;do{if(0===A.avail_out&&(A.output=new i.Buf8(c),A.next_out=0,A.avail_out=c),1!==(r=n.deflate(A,s))&&0!==r)return this.onEnd(r),this.ended=!0,!1;0!==A.avail_out&&(0!==A.avail_in||4!==s&&2!==s)||("string"===this.options.to?this.onData(a.buf2binstring(i.shrinkBuf(A.output,A.next_out))):this.onData(i.shrinkBuf(A.output,A.next_out)));}while((A.avail_in>0||0===A.avail_out)&&1!==r);return 4===s?(r=n.deflateEnd(this.strm),this.onEnd(r),this.ended=!0,0===r):2!==s||(this.onEnd(0),A.avail_out=0,!0)},c.prototype.onData=function(e){this.chunks.push(e);},c.prototype.onEnd=function(e){0===e&&("string"===this.options.to?this.result=this.chunks.join(""):this.result=i.flattenChunks(this.chunks)),this.chunks=[],this.err=e,this.msg=this.strm.msg;},t.Deflate=c,t.deflate=d,t.deflateRaw=function(e,t){return (t=t||{}).raw=!0,d(e,t)},t.gzip=function(e,t){return (t=t||{}).gzip=!0,d(e,t)};},3503:(e,t,r)=>{var n,i,a,s,A;n=r(3939),i=r(2151).utf8,a=r(652),s=r(2151).bin,(A=function(e,t){e.constructor==String?e=t&&"binary"===t.encoding?s.stringToBytes(e):i.stringToBytes(e):a(e)?e=Array.prototype.slice.call(e,0):Array.isArray(e)||e.constructor===Uint8Array||(e=e.toString());for(var r=n.bytesToWords(e),o=8*e.length,c=1732584193,d=-271733879,l=-1732584194,f=271733878,u=0;u<r.length;u++)r[u]=16711935&(r[u]<<8|r[u]>>>24)|4278255360&(r[u]<<24|r[u]>>>8);r[o>>>5]|=128<<o%32,r[14+(o+64>>>9<<4)]=o;var g=A._ff,h=A._gg,C=A._hh,I=A._ii;for(u=0;u<r.length;u+=16){var _=c,m=d,B=l,p=f;c=g(c,d,l,f,r[u+0],7,-680876936),f=g(f,c,d,l,r[u+1],12,-389564586),l=g(l,f,c,d,r[u+2],17,606105819),d=g(d,l,f,c,r[u+3],22,-1044525330),c=g(c,d,l,f,r[u+4],7,-176418897),f=g(f,c,d,l,r[u+5],12,1200080426),l=g(l,f,c,d,r[u+6],17,-1473231341),d=g(d,l,f,c,r[u+7],22,-45705983),c=g(c,d,l,f,r[u+8],7,1770035416),f=g(f,c,d,l,r[u+9],12,-1958414417),l=g(l,f,c,d,r[u+10],17,-42063),d=g(d,l,f,c,r[u+11],22,-1990404162),c=g(c,d,l,f,r[u+12],7,1804603682),f=g(f,c,d,l,r[u+13],12,-40341101),l=g(l,f,c,d,r[u+14],17,-1502002290),c=h(c,d=g(d,l,f,c,r[u+15],22,1236535329),l,f,r[u+1],5,-165796510),f=h(f,c,d,l,r[u+6],9,-1069501632),l=h(l,f,c,d,r[u+11],14,643717713),d=h(d,l,f,c,r[u+0],20,-373897302),c=h(c,d,l,f,r[u+5],5,-701558691),f=h(f,c,d,l,r[u+10],9,38016083),l=h(l,f,c,d,r[u+15],14,-660478335),d=h(d,l,f,c,r[u+4],20,-405537848),c=h(c,d,l,f,r[u+9],5,568446438),f=h(f,c,d,l,r[u+14],9,-1019803690),l=h(l,f,c,d,r[u+3],14,-187363961),d=h(d,l,f,c,r[u+8],20,1163531501),c=h(c,d,l,f,r[u+13],5,-1444681467),f=h(f,c,d,l,r[u+2],9,-51403784),l=h(l,f,c,d,r[u+7],14,1735328473),c=C(c,d=h(d,l,f,c,r[u+12],20,-1926607734),l,f,r[u+5],4,-378558),f=C(f,c,d,l,r[u+8],11,-2022574463),l=C(l,f,c,d,r[u+11],16,1839030562),d=C(d,l,f,c,r[u+14],23,-35309556),c=C(c,d,l,f,r[u+1],4,-1530992060),f=C(f,c,d,l,r[u+4],11,1272893353),l=C(l,f,c,d,r[u+7],16,-155497632),d=C(d,l,f,c,r[u+10],23,-1094730640),c=C(c,d,l,f,r[u+13],4,681279174),f=C(f,c,d,l,r[u+0],11,-358537222),l=C(l,f,c,d,r[u+3],16,-722521979),d=C(d,l,f,c,r[u+6],23,76029189),c=C(c,d,l,f,r[u+9],4,-640364487),f=C(f,c,d,l,r[u+12],11,-421815835),l=C(l,f,c,d,r[u+15],16,530742520),c=I(c,d=C(d,l,f,c,r[u+2],23,-995338651),l,f,r[u+0],6,-198630844),f=I(f,c,d,l,r[u+7],10,1126891415),l=I(l,f,c,d,r[u+14],15,-1416354905),d=I(d,l,f,c,r[u+5],21,-57434055),c=I(c,d,l,f,r[u+12],6,1700485571),f=I(f,c,d,l,r[u+3],10,-1894986606),l=I(l,f,c,d,r[u+10],15,-1051523),d=I(d,l,f,c,r[u+1],21,-2054922799),c=I(c,d,l,f,r[u+8],6,1873313359),f=I(f,c,d,l,r[u+15],10,-30611744),l=I(l,f,c,d,r[u+6],15,-1560198380),d=I(d,l,f,c,r[u+13],21,1309151649),c=I(c,d,l,f,r[u+4],6,-145523070),f=I(f,c,d,l,r[u+11],10,-1120210379),l=I(l,f,c,d,r[u+2],15,718787259),d=I(d,l,f,c,r[u+9],21,-343485551),c=c+_>>>0,d=d+m>>>0,l=l+B>>>0,f=f+p>>>0;}return n.endian([c,d,l,f])})._ff=function(e,t,r,n,i,a,s){var A=e+(t&r|~t&n)+(i>>>0)+s;return (A<<a|A>>>32-a)+t},A._gg=function(e,t,r,n,i,a,s){var A=e+(t&n|r&~n)+(i>>>0)+s;return (A<<a|A>>>32-a)+t},A._hh=function(e,t,r,n,i,a,s){var A=e+(t^r^n)+(i>>>0)+s;return (A<<a|A>>>32-a)+t},A._ii=function(e,t,r,n,i,a,s){var A=e+(r^(t|~n))+(i>>>0)+s;return (A<<a|A>>>32-a)+t},A._blocksize=16,A._digestsize=16,e.exports=function(e,t){if(null==e)throw new Error("Illegal argument "+e);var r=n.wordsToBytes(A(e,t));return t&&t.asBytes?r:t&&t.asString?s.bytesToString(r):n.bytesToHex(r)};},3665:(e,t,r)=>{var n=r(9805);function i(e){for(var t=e.length;--t>=0;)e[t]=0;}var a=[0,0,0,0,0,0,0,0,1,1,1,1,2,2,2,2,3,3,3,3,4,4,4,4,5,5,5,5,0],s=[0,0,0,0,1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,12,12,13,13],A=[0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,0,2,3,7],o=[16,17,18,0,8,7,9,6,10,5,11,4,12,3,13,2,14,1,15],c=new Array(576);i(c);var d=new Array(60);i(d);var l=new Array(512);i(l);var f=new Array(256);i(f);var u=new Array(29);i(u);var g,h,C,I=new Array(30);function _(e,t,r,n,i){this.static_tree=e,this.extra_bits=t,this.extra_base=r,this.elems=n,this.max_length=i,this.has_stree=e&&e.length;}function m(e,t){this.dyn_tree=e,this.max_code=0,this.stat_desc=t;}function B(e){return e<256?l[e]:l[256+(e>>>7)]}function p(e,t){e.pending_buf[e.pending++]=255&t,e.pending_buf[e.pending++]=t>>>8&255;}function w(e,t,r){e.bi_valid>16-r?(e.bi_buf|=t<<e.bi_valid&65535,p(e,e.bi_buf),e.bi_buf=t>>16-e.bi_valid,e.bi_valid+=r-16):(e.bi_buf|=t<<e.bi_valid&65535,e.bi_valid+=r);}function E(e,t,r){w(e,r[2*t],r[2*t+1]);}function Q(e,t){var r=0;do{r|=1&e,e>>>=1,r<<=1;}while(--t>0);return r>>>1}function y(e,t,r){var n,i,a=new Array(16),s=0;for(n=1;n<=15;n++)a[n]=s=s+r[n-1]<<1;for(i=0;i<=t;i++){var A=e[2*i+1];0!==A&&(e[2*i]=Q(a[A]++,A));}}function b(e){var t;for(t=0;t<286;t++)e.dyn_ltree[2*t]=0;for(t=0;t<30;t++)e.dyn_dtree[2*t]=0;for(t=0;t<19;t++)e.bl_tree[2*t]=0;e.dyn_ltree[512]=1,e.opt_len=e.static_len=0,e.last_lit=e.matches=0;}function D(e){e.bi_valid>8?p(e,e.bi_buf):e.bi_valid>0&&(e.pending_buf[e.pending++]=e.bi_buf),e.bi_buf=0,e.bi_valid=0;}function S(e,t,r,n){var i=2*t,a=2*r;return e[i]<e[a]||e[i]===e[a]&&n[t]<=n[r]}function k(e,t,r){for(var n=e.heap[r],i=r<<1;i<=e.heap_len&&(i<e.heap_len&&S(t,e.heap[i+1],e.heap[i],e.depth)&&i++,!S(t,n,e.heap[i],e.depth));)e.heap[r]=e.heap[i],r=i,i<<=1;e.heap[r]=n;}function v(e,t,r){var n,i,A,o,c=0;if(0!==e.last_lit)do{n=e.pending_buf[e.d_buf+2*c]<<8|e.pending_buf[e.d_buf+2*c+1],i=e.pending_buf[e.l_buf+c],c++,0===n?E(e,i,t):(E(e,(A=f[i])+256+1,t),0!==(o=a[A])&&w(e,i-=u[A],o),E(e,A=B(--n),r),0!==(o=s[A])&&w(e,n-=I[A],o));}while(c<e.last_lit);E(e,256,t);}function R(e,t){var r,n,i,a=t.dyn_tree,s=t.stat_desc.static_tree,A=t.stat_desc.has_stree,o=t.stat_desc.elems,c=-1;for(e.heap_len=0,e.heap_max=573,r=0;r<o;r++)0!==a[2*r]?(e.heap[++e.heap_len]=c=r,e.depth[r]=0):a[2*r+1]=0;for(;e.heap_len<2;)a[2*(i=e.heap[++e.heap_len]=c<2?++c:0)]=1,e.depth[i]=0,e.opt_len--,A&&(e.static_len-=s[2*i+1]);for(t.max_code=c,r=e.heap_len>>1;r>=1;r--)k(e,a,r);i=o;do{r=e.heap[1],e.heap[1]=e.heap[e.heap_len--],k(e,a,1),n=e.heap[1],e.heap[--e.heap_max]=r,e.heap[--e.heap_max]=n,a[2*i]=a[2*r]+a[2*n],e.depth[i]=(e.depth[r]>=e.depth[n]?e.depth[r]:e.depth[n])+1,a[2*r+1]=a[2*n+1]=i,e.heap[1]=i++,k(e,a,1);}while(e.heap_len>=2);e.heap[--e.heap_max]=e.heap[1],function(e,t){var r,n,i,a,s,A,o=t.dyn_tree,c=t.max_code,d=t.stat_desc.static_tree,l=t.stat_desc.has_stree,f=t.stat_desc.extra_bits,u=t.stat_desc.extra_base,g=t.stat_desc.max_length,h=0;for(a=0;a<=15;a++)e.bl_count[a]=0;for(o[2*e.heap[e.heap_max]+1]=0,r=e.heap_max+1;r<573;r++)(a=o[2*o[2*(n=e.heap[r])+1]+1]+1)>g&&(a=g,h++),o[2*n+1]=a,n>c||(e.bl_count[a]++,s=0,n>=u&&(s=f[n-u]),A=o[2*n],e.opt_len+=A*(a+s),l&&(e.static_len+=A*(d[2*n+1]+s)));if(0!==h){do{for(a=g-1;0===e.bl_count[a];)a--;e.bl_count[a]--,e.bl_count[a+1]+=2,e.bl_count[g]--,h-=2;}while(h>0);for(a=g;0!==a;a--)for(n=e.bl_count[a];0!==n;)(i=e.heap[--r])>c||(o[2*i+1]!==a&&(e.opt_len+=(a-o[2*i+1])*o[2*i],o[2*i+1]=a),n--);}}(e,t),y(a,c,e.bl_count);}function F(e,t,r){var n,i,a=-1,s=t[1],A=0,o=7,c=4;for(0===s&&(o=138,c=3),t[2*(r+1)+1]=65535,n=0;n<=r;n++)i=s,s=t[2*(n+1)+1],++A<o&&i===s||(A<c?e.bl_tree[2*i]+=A:0!==i?(i!==a&&e.bl_tree[2*i]++,e.bl_tree[32]++):A<=10?e.bl_tree[34]++:e.bl_tree[36]++,A=0,a=i,0===s?(o=138,c=3):i===s?(o=6,c=3):(o=7,c=4));}function M(e,t,r){var n,i,a=-1,s=t[1],A=0,o=7,c=4;for(0===s&&(o=138,c=3),n=0;n<=r;n++)if(i=s,s=t[2*(n+1)+1],!(++A<o&&i===s)){if(A<c)do{E(e,i,e.bl_tree);}while(0!==--A);else 0!==i?(i!==a&&(E(e,i,e.bl_tree),A--),E(e,16,e.bl_tree),w(e,A-3,2)):A<=10?(E(e,17,e.bl_tree),w(e,A-3,3)):(E(e,18,e.bl_tree),w(e,A-11,7));A=0,a=i,0===s?(o=138,c=3):i===s?(o=6,c=3):(o=7,c=4);}}i(I);var N=!1;function x(e,t,r,i){w(e,0+(i?1:0),3),function(e,t,r){D(e),p(e,r),p(e,~r),n.arraySet(e.pending_buf,e.window,t,r,e.pending),e.pending+=r;}(e,t,r);}t._tr_init=function(e){N||(function(){var e,t,r,n,i,o=new Array(16);for(r=0,n=0;n<28;n++)for(u[n]=r,e=0;e<1<<a[n];e++)f[r++]=n;for(f[r-1]=n,i=0,n=0;n<16;n++)for(I[n]=i,e=0;e<1<<s[n];e++)l[i++]=n;for(i>>=7;n<30;n++)for(I[n]=i<<7,e=0;e<1<<s[n]-7;e++)l[256+i++]=n;for(t=0;t<=15;t++)o[t]=0;for(e=0;e<=143;)c[2*e+1]=8,e++,o[8]++;for(;e<=255;)c[2*e+1]=9,e++,o[9]++;for(;e<=279;)c[2*e+1]=7,e++,o[7]++;for(;e<=287;)c[2*e+1]=8,e++,o[8]++;for(y(c,287,o),e=0;e<30;e++)d[2*e+1]=5,d[2*e]=Q(e,5);g=new _(c,a,257,286,15),h=new _(d,s,0,30,15),C=new _(new Array(0),A,0,19,7);}(),N=!0),e.l_desc=new m(e.dyn_ltree,g),e.d_desc=new m(e.dyn_dtree,h),e.bl_desc=new m(e.bl_tree,C),e.bi_buf=0,e.bi_valid=0,b(e);},t._tr_stored_block=x,t._tr_flush_block=function(e,t,r,n){var i,a,s=0;e.level>0?(2===e.strm.data_type&&(e.strm.data_type=function(e){var t,r=4093624447;for(t=0;t<=31;t++,r>>>=1)if(1&r&&0!==e.dyn_ltree[2*t])return 0;if(0!==e.dyn_ltree[18]||0!==e.dyn_ltree[20]||0!==e.dyn_ltree[26])return 1;for(t=32;t<256;t++)if(0!==e.dyn_ltree[2*t])return 1;return 0}(e)),R(e,e.l_desc),R(e,e.d_desc),s=function(e){var t;for(F(e,e.dyn_ltree,e.l_desc.max_code),F(e,e.dyn_dtree,e.d_desc.max_code),R(e,e.bl_desc),t=18;t>=3&&0===e.bl_tree[2*o[t]+1];t--);return e.opt_len+=3*(t+1)+5+5+4,t}(e),i=e.opt_len+3+7>>>3,(a=e.static_len+3+7>>>3)<=i&&(i=a)):i=a=r+5,r+4<=i&&-1!==t?x(e,t,r,n):4===e.strategy||a===i?(w(e,2+(n?1:0),3),v(e,c,d)):(w(e,4+(n?1:0),3),function(e,t,r,n){var i;for(w(e,t-257,5),w(e,r-1,5),w(e,n-4,4),i=0;i<n;i++)w(e,e.bl_tree[2*o[i]+1],3);M(e,e.dyn_ltree,t-1),M(e,e.dyn_dtree,r-1);}(e,e.l_desc.max_code+1,e.d_desc.max_code+1,s+1),v(e,e.dyn_ltree,e.dyn_dtree)),b(e),n&&D(e);},t._tr_tally=function(e,t,r){return e.pending_buf[e.d_buf+2*e.last_lit]=t>>>8&255,e.pending_buf[e.d_buf+2*e.last_lit+1]=255&t,e.pending_buf[e.l_buf+e.last_lit]=255&r,e.last_lit++,0===t?e.dyn_ltree[2*r]++:(e.matches++,t--,e.dyn_ltree[2*(f[r]+256+1)]++,e.dyn_dtree[2*B(t)]++),e.last_lit===e.lit_bufsize-1},t._tr_align=function(e){w(e,2,3),E(e,256,c),function(e){16===e.bi_valid?(p(e,e.bi_buf),e.bi_buf=0,e.bi_valid=0):e.bi_valid>=8&&(e.pending_buf[e.pending++]=255&e.bi_buf,e.bi_buf>>=8,e.bi_valid-=8);}(e);};},3939:e=>{var t,r;t="ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/",r={rotl:function(e,t){return e<<t|e>>>32-t},rotr:function(e,t){return e<<32-t|e>>>t},endian:function(e){if(e.constructor==Number)return 16711935&r.rotl(e,8)|4278255360&r.rotl(e,24);for(var t=0;t<e.length;t++)e[t]=r.endian(e[t]);return e},randomBytes:function(e){for(var t=[];e>0;e--)t.push(Math.floor(256*Math.random()));return t},bytesToWords:function(e){for(var t=[],r=0,n=0;r<e.length;r++,n+=8)t[n>>>5]|=e[r]<<24-n%32;return t},wordsToBytes:function(e){for(var t=[],r=0;r<32*e.length;r+=8)t.push(e[r>>>5]>>>24-r%32&255);return t},bytesToHex:function(e){for(var t=[],r=0;r<e.length;r++)t.push((e[r]>>>4).toString(16)),t.push((15&e[r]).toString(16));return t.join("")},hexToBytes:function(e){for(var t=[],r=0;r<e.length;r+=2)t.push(parseInt(e.substr(r,2),16));return t},bytesToBase64:function(e){for(var r=[],n=0;n<e.length;n+=3)for(var i=e[n]<<16|e[n+1]<<8|e[n+2],a=0;a<4;a++)8*n+6*a<=8*e.length?r.push(t.charAt(i>>>6*(3-a)&63)):r.push("=");return r.join("")},base64ToBytes:function(e){e=e.replace(/[^A-Z0-9+\/]/gi,"");for(var r=[],n=0,i=0;n<e.length;i=++n%4)0!=i&&r.push((t.indexOf(e.charAt(n-1))&Math.pow(2,-2*i+8)-1)<<2*i|t.indexOf(e.charAt(n))>>>6-2*i);return r}},e.exports=r;},4056:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(6761),s=r(6272);class A extends i.default{constructor(e,t){if(super(e,t),this.codes={},this.codeBook={},this.sortedCodes=[],this.sortedValuesByBitCode=[],this.sortedBitCodes=[],this.sortedBitLengthsByBitCode=[],this.bitCodeToValue=[],!["byte","int"].includes(this.dataType))throw new TypeError(`${this.dataType} decoding not yet implemented by HUFFMAN_INT codec`);this.buildCodeBook(),this.buildCodes(),this.buildCaches(),0===this.sortedCodes[0].bitLength&&(this._decode=this._decodeZeroLengthCode);}buildCodeBook(){let e=new Array(this.parameters.numCodes);for(let t=0;t<this.parameters.numCodes;t++)e[t]={symbol:this.parameters.symbols[t],bitLength:this.parameters.bitLengths[t]};e=e.sort(((e,t)=>e.bitLength-t.bitLength||e.symbol-t.symbol)),this.codeBook={},e.forEach((e=>{this.codeBook[e.bitLength]||(this.codeBook[e.bitLength]=[]),this.codeBook[e.bitLength].push(e.symbol);}));}buildCodes(){this.codes={};let e=0,t=-1;Object.entries(this.codeBook).forEach((([r,n])=>{const i=Number.parseInt(r,10);n.forEach((r=>{const n={bitLength:i,value:r,bitCode:0};t+=1;const a=i-e;if(t<<=a,n.bitCode=t,e+=a,function(e){let t=e-(e>>1)&1431655765;return t=(858993459&t)+(t>>2&858993459),16843009*(t+(t>>4)&252645135)>>24}(t)>i)throw new s.CramMalformedError("Symbol out of range");this.codes[r]=n;}));}));}buildCaches(){this.sortedCodes=Object.values(this.codes).sort(((e,t)=>e.bitLength-t.bitLength||e.bitCode-t.bitCode)),this.sortedValuesByBitCode=this.sortedCodes.map((e=>e.value)),this.sortedBitCodes=this.sortedCodes.map((e=>e.bitCode)),this.sortedBitLengthsByBitCode=this.sortedCodes.map((e=>e.bitLength));const e=Math.max(...this.sortedBitCodes);this.bitCodeToValue=new Array(e+1).fill(-1);for(let e=0;e<this.sortedBitCodes.length;e+=1)this.bitCodeToValue[this.sortedCodes[e].bitCode]=e;}decode(e,t,r,n){return this._decode(e,t,n.coreBlock)}_decodeZeroLengthCode(){return this.sortedCodes[0].value}_decode(e,t,r){const n=t.content;let i=0,A=0;for(let e=0;e<this.sortedCodes.length;e+=1){const t=this.sortedCodes[e].bitLength;A<<=t-i,A|=(0, a.getBits)(n,r,t-i),i=t;{const r=this.bitCodeToValue[A];if(r>-1&&this.sortedBitLengthsByBitCode[r]===t)return this.sortedValuesByBitCode[r];for(let r=e;this.sortedCodes[r+1].bitLength===t&&r<this.sortedCodes.length;r+=1)e+=1;}}throw new s.CramMalformedError("Huffman symbol not found.")}}t.default=A;},4141:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(e,t){this.parameters=e,this.dataType=t;}};},4442:e=>{e.exports=function(){this.input=null,this.next_in=0,this.avail_in=0,this.total_in=0,this.output=null,this.next_out=0,this.avail_out=0,this.total_out=0,this.msg="",this.state=null,this.data_type=2,this.adler=0;};},4562:function(e,t,r){var n,i=this&&this.__createBinding||(Object.create?function(e,t,r,n){void 0===n&&(n=r);var i=Object.getOwnPropertyDescriptor(t,r);i&&!("get"in i?!t.__esModule:i.writable||i.configurable)||(i={enumerable:!0,get:function(){return t[r]}}),Object.defineProperty(e,n,i);}:function(e,t,r,n){void 0===n&&(n=r),e[n]=t[r];}),a=this&&this.__setModuleDefault||(Object.create?function(e,t){Object.defineProperty(e,"default",{enumerable:!0,value:t});}:function(e,t){e.default=t;}),s=this&&this.__importStar||(n=function(e){return n=Object.getOwnPropertyNames||function(e){var t=[];for(var r in e)Object.prototype.hasOwnProperty.call(e,r)&&(t[t.length]=r);return t},n(e)},function(e){if(e&&e.__esModule)return e;var t={};if(null!=e)for(var r=n(e),s=0;s<r.length;s++)"default"!==r[s]&&i(t,e,r[s]);return a(t,e),t}),A=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.r4x8_uncompress=function(e){return d.decode(e)},t.r4x16_uncompress=function(e){return l.decode(e)},t.arith_uncompress=function(e){return (new o.default).decode(e)},t.fqzcomp_uncompress=function(e){return c.decode(e,[])},t.tok3_uncompress=function(e){const t=f.decode(e,0,"\0");return Uint8Array.from(Array.from(t).map((e=>e.charCodeAt(0))))};const o=A(r(9505)),c=s(r(2660)),d=s(r(8594)),l=s(r(9313)),f=s(r(1739));},4652:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(e){this.low=0,this.range=4294967295,this.code=0,this.FFnum=0,this.carry=0,this.cache=0;}RangeStartDecode(e){for(let t=0;t<5;t++)this.code=(this.code<<8)+e.ReadByte();this.code&=4294967295,this.code>>>=0;}RangeGetFrequency(e){return this.range=Math.floor(this.range/e),Math.floor(this.code/this.range)}RangeDecode(e,t,r,n){for(this.code-=t*this.range,this.range*=r;this.range<1<<24;)this.range*=256,this.code=256*this.code+e.ReadByte();}RangeShiftLow(e){if(this.low<4278190080|this.carry){for(e.WriteByte(this.cache+this.carry);this.FFnum;)e.WriteByte(this.carry-1),this.FFnum--;this.cache=this.low>>>24,this.carry=0;}else this.FFnum++;this.low<<=8,this.low>>>=0;}RangeEncode(e,t,r,n){const i=this.low;for(this.range=Math.floor(this.range/n),this.low+=t*this.range,this.low>>>=0,this.range*=r,this.low<i&&(0!=this.carry&&console.log("ERROR: Multiple carry"),this.carry=1);this.range<1<<24;)this.range*=256,this.RangeShiftLow(e);}RangeFinishEncode(e){for(let t=0;t<5;t++)this.RangeShiftLow(e);}};},4674:e=>{e.exports={2:"need dictionary",1:"stream end",0:"","-1":"file error","-2":"stream error","-3":"data error","-4":"insufficient memory","-5":"buffer error","-6":"incompatible version"};},4823:e=>{var t=function(){for(var e,t=[],r=0;r<256;r++){e=r;for(var n=0;n<8;n++)e=1&e?3988292384^e>>>1:e>>>1;t[r]=e;}return t}();e.exports=function(e,r,n,i){var a=t,s=i+n;e^=-1;for(var A=i;A<s;A++)e=e>>>8^a[255&(e^r[A])];return -1^e};},4997:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.default=t.CramRecord=void 0;var i=r(7480);Object.defineProperty(t,"CramRecord",{enumerable:!0,get:function(){return n(i).default}});var a=r(8751);Object.defineProperty(t,"default",{enumerable:!0,get:function(){return n(a).default}});},5011:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.parseHeaderText=function(e){const t=e.split(/\r?\n/),r=[];for(const e of t){const[t,...n]=e.split(/\t/);t&&r.push({tag:t.slice(1),data:n.map((e=>{const t=e.indexOf(":");return -1!==t?{tag:e.slice(0,t),value:e.slice(t+1)}:{tag:e,value:""}}))});}return r};},5159:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.IndexedCramFile=t.CraiIndex=t.CramFile=t.CramRecord=void 0;var i=r(4997);Object.defineProperty(t,"CramRecord",{enumerable:!0,get:function(){return i.CramRecord}}),Object.defineProperty(t,"CramFile",{enumerable:!0,get:function(){return n(i).default}});var a=r(6638);Object.defineProperty(t,"CraiIndex",{enumerable:!0,get:function(){return n(a).default}});var s=r(8223);Object.defineProperty(t,"IndexedCramFile",{enumerable:!0,get:function(){return n(s).default}});},6268:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.readStatsO0=function(e,t,r){let n=0,i=0,o=255&e.get();do{null==t.fc[o]&&(t.fc[o]=new s.default.FC),t.fc[o].F=255&e.get(),t.fc[o].F>=128&&(t.fc[o].F&=-129,t.fc[o].F=(127&t.fc[o].F)<<8|255&e.get()),t.fc[o].C=i,s.default.symbolInit(r[o],t.fc[o].C,t.fc[o].F),t.R||(t.R=new Array(a.TOTFREQ)),t.R.fill(o,i,i+t.fc[o].F),i+=t.fc[o].F,0===n&&o+1===(255&e.getByteAt(e.position()))?(o=255&e.get(),n=255&e.get()):0!==n?(n-=1,o+=1):o=255&e.get();}while(0!==o);A(i<a.TOTFREQ);},t.readStatsO1=function(e,t,r){let n=0,i=255&e.get();do{let o=0,c=0,d=255&e.get();null==t[i]&&(t[i]=new s.default.AriDecoder);do{null==t[i].fc[d]&&(t[i].fc[d]=new s.default.FC),t[i].fc[d].F=255&e.get(),t[i].fc[d].F>=128&&(t[i].fc[d].F&=-129,t[i].fc[d].F=(127&t[i].fc[d].F)<<8|255&e.get()),t[i].fc[d].C=c,0===t[i].fc[d].F&&(t[i].fc[d].F=a.TOTFREQ),null==r[i][d]&&(r[i][d]=new s.default.RansDecSymbol),s.default.symbolInit(r[i][d],t[i].fc[d].C,t[i].fc[d].F),null==t[i].R&&(t[i].R=new Array(a.TOTFREQ)),t[i].R.fill(d,c,c+t[i].fc[d].F),c+=t[i].fc[d].F,A(c<=a.TOTFREQ),0===o&&d+1===(255&e.getByteAt(e.position()))?(d=255&e.get(),o=255&e.get()):0!==o?(o-=1,d+=1):d=255&e.get();}while(0!==d);0===n&&i+1===(255&e.getByteAt(e.position()))?(i=255&e.get(),n=255&e.get()):0!==n?(n-=1,i+=1):i=255&e.get();}while(0!==i)};const i=r(6272),a=r(7151),s=n(r(9301));function A(e){if(!e)throw new i.CramMalformedError("assertion failed")}},6272:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.CramArgumentError=t.CramSizeLimitError=t.CramMalformedError=t.CramUnimplementedError=t.CramError=void 0;class r extends Error{}t.CramError=r;class n extends Error{}t.CramUnimplementedError=n,t.CramMalformedError=class extends r{},t.CramSizeLimitError=class extends r{},t.CramArgumentError=class extends r{};},6612:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{readByte(){throw new Error("abstract method readByte() not implemented")}read(e,t,r){let n=0;for(;n<r;){const r=this.readByte();if(r<0)return 0===n?-1:n;e[t++]=r,n++;}return n}writeByte(e){throw new Error("abstract method readByte() not implemented")}seek(e){throw new Error("abstract method seek() not implemented")}write(e,t,r){let n;for(n=0;n<r;n++)this.writeByte(e[t++]);return r}flush(){}};},6638:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0});const n=r(6272),i=r(6727),a=r(2169);function s(e,t){const[r,n,i,a,s,A]=t,o=r;e[o]||(e[o]=[]),e[o].push({start:n,span:i,containerStart:a,sliceStart:s,sliceBytes:A});}t.default=class{constructor(e){this.filehandle=(0, i.open)(e.url,e.path,e.filehandle);}async parseIndex(){const e={},t=31===(r=await this.filehandle.readFile())[0]&&139===r[1]?(0, a.unzip)(r):r;var r;const i=new DataView(t.buffer);if(t.length>4&&21578050===i.getUint32(0,!0))throw new n.CramMalformedError("invalid .crai index file. note: file appears to be a .bai index. this is technically legal but please open a github issue if you need support");let A=[],o="";for(const r of t)if(r>=48&&r<=57||!o&&45===r)o+=String.fromCharCode(r);else if(9===r)A.push(Number.parseInt(o,10)),o="";else if(10===r)A.push(Number.parseInt(o,10)),o="",s(e,A),A=[];else if(13!==r&&32!==r)throw new n.CramMalformedError("invalid .crai index file");return o&&A.push(Number.parseInt(o,10)),6===A.length&&s(e,A),Object.entries(e).forEach((([t,r])=>{const n=r;e[t]=n.sort(((e,t)=>e.start-t.start||e.span-t.span));})),e}getIndex(){return this.parseIndexP||(this.parseIndexP=this.parseIndex().catch((e=>{throw this.parseIndexP=void 0,e}))),this.parseIndexP}async hasDataForReferenceSequence(e){return !!(await this.getIndex())[e]}async getEntriesForRange(e,t,r){const n=(await this.getIndex())[e];if(!n)return [];const i=e=>{const n=e.start,i=e.start+e.span;return n>r?-1:i<=t?1:0},a=[];for(const e of n)0===i(e)&&a.push(e);return a}};},6727:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.RemoteFile=t.LocalFile=void 0,t.open=function(e,t,r){if(r)return r;if(e)return new n.RemoteFile(e);if(t)return new n.LocalFile(t);throw new Error("no url, path, or filehandle provided, cannot open")};const n=r(8301);var i=r(8301);Object.defineProperty(t,"LocalFile",{enumerable:!0,get:function(){return i.LocalFile}}),Object.defineProperty(t,"RemoteFile",{enumerable:!0,get:function(){return i.RemoteFile}});},6761:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.CramBufferOverrunError=void 0,t.getBits=function(e,t,n){let i=0;if(t.bytePosition+(7-t.bitPosition+n)/8>e.length)throw new r("read error during decoding. the file seems to be truncated.");for(let r=n;r;r--)i<<=1,i|=e[t.bytePosition]>>t.bitPosition&1,t.bitPosition-=1,t.bitPosition<0&&(t.bytePosition+=1),t.bitPosition&=7;return i};class r extends Error{}t.CramBufferOverrunError=r;},6951:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.concatUint8Array=function(e){const t=new Uint8Array(function(e){let t=0;for(const r of e)t+=r.length;return t}(e));let r=0;for(const n of e)t.set(n,r),r+=n.length;return t};},7083:(e,t,r)=>{var n=r(1447),i=r(9805),a=r(1996),s=r(9681),A=r(4674),o=r(4442),c=r(7414),d=Object.prototype.toString;function l(e){if(!(this instanceof l))return new l(e);this.options=i.assign({chunkSize:16384,windowBits:0,to:""},e||{});var t=this.options;t.raw&&t.windowBits>=0&&t.windowBits<16&&(t.windowBits=-t.windowBits,0===t.windowBits&&(t.windowBits=-15)),!(t.windowBits>=0&&t.windowBits<16)||e&&e.windowBits||(t.windowBits+=32),t.windowBits>15&&t.windowBits<48&&(15&t.windowBits||(t.windowBits|=15)),this.err=0,this.msg="",this.ended=!1,this.chunks=[],this.strm=new o,this.strm.avail_out=0;var r=n.inflateInit2(this.strm,t.windowBits);if(r!==s.Z_OK)throw new Error(A[r]);if(this.header=new c,n.inflateGetHeader(this.strm,this.header),t.dictionary&&("string"==typeof t.dictionary?t.dictionary=a.string2buf(t.dictionary):"[object ArrayBuffer]"===d.call(t.dictionary)&&(t.dictionary=new Uint8Array(t.dictionary)),t.raw&&(r=n.inflateSetDictionary(this.strm,t.dictionary))!==s.Z_OK))throw new Error(A[r])}function f(e,t){var r=new l(t);if(r.push(e,!0),r.err)throw r.msg||A[r.err];return r.result}l.prototype.push=function(e,t){var r,A,o,c,l,f=this.strm,u=this.options.chunkSize,g=this.options.dictionary,h=!1;if(this.ended)return !1;A=t===~~t?t:!0===t?s.Z_FINISH:s.Z_NO_FLUSH,"string"==typeof e?f.input=a.binstring2buf(e):"[object ArrayBuffer]"===d.call(e)?f.input=new Uint8Array(e):f.input=e,f.next_in=0,f.avail_in=f.input.length;do{if(0===f.avail_out&&(f.output=new i.Buf8(u),f.next_out=0,f.avail_out=u),(r=n.inflate(f,s.Z_NO_FLUSH))===s.Z_NEED_DICT&&g&&(r=n.inflateSetDictionary(this.strm,g)),r===s.Z_BUF_ERROR&&!0===h&&(r=s.Z_OK,h=!1),r!==s.Z_STREAM_END&&r!==s.Z_OK)return this.onEnd(r),this.ended=!0,!1;f.next_out&&(0!==f.avail_out&&r!==s.Z_STREAM_END&&(0!==f.avail_in||A!==s.Z_FINISH&&A!==s.Z_SYNC_FLUSH)||("string"===this.options.to?(o=a.utf8border(f.output,f.next_out),c=f.next_out-o,l=a.buf2string(f.output,o),f.next_out=c,f.avail_out=u-c,c&&i.arraySet(f.output,f.output,o,c,0),this.onData(l)):this.onData(i.shrinkBuf(f.output,f.next_out)))),0===f.avail_in&&0===f.avail_out&&(h=!0);}while((f.avail_in>0||0===f.avail_out)&&r!==s.Z_STREAM_END);return r===s.Z_STREAM_END&&(A=s.Z_FINISH),A===s.Z_FINISH?(r=n.inflateEnd(this.strm),this.onEnd(r),this.ended=!0,r===s.Z_OK):A!==s.Z_SYNC_FLUSH||(this.onEnd(s.Z_OK),f.avail_out=0,!0)},l.prototype.onData=function(e){this.chunks.push(e);},l.prototype.onEnd=function(e){e===s.Z_OK&&("string"===this.options.to?this.result=this.chunks.join(""):this.result=i.flattenChunks(this.chunks)),this.chunks=[],this.err=e,this.msg=this.strm.msg;},t.Inflate=l,t.inflate=f,t.inflateRaw=function(e,t){return (t=t||{}).raw=!0,f(e,t)},t.ungzip=f;},7151:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.TOTFREQ=t.TF_SHIFT=t.RANS_BYTE_L=void 0,t.TF_SHIFT=12,t.TOTFREQ=4096,t.RANS_BYTE_L=1<<23;},7293:e=>{e.exports=function(e,t){var r,n,i,a,s,A,o,c,d,l,f,u,g,h,C,I,_,m,B,p,w,E,Q,y,b;r=e.state,n=e.next_in,y=e.input,i=n+(e.avail_in-5),a=e.next_out,b=e.output,s=a-(t-e.avail_out),A=a+(e.avail_out-257),o=r.dmax,c=r.wsize,d=r.whave,l=r.wnext,f=r.window,u=r.hold,g=r.bits,h=r.lencode,C=r.distcode,I=(1<<r.lenbits)-1,_=(1<<r.distbits)-1;e:do{g<15&&(u+=y[n++]<<g,g+=8,u+=y[n++]<<g,g+=8),m=h[u&I];t:for(;;){if(u>>>=B=m>>>24,g-=B,0==(B=m>>>16&255))b[a++]=65535&m;else {if(!(16&B)){if(64&B){if(32&B){r.mode=12;break e}e.msg="invalid literal/length code",r.mode=30;break e}m=h[(65535&m)+(u&(1<<B)-1)];continue t}for(p=65535&m,(B&=15)&&(g<B&&(u+=y[n++]<<g,g+=8),p+=u&(1<<B)-1,u>>>=B,g-=B),g<15&&(u+=y[n++]<<g,g+=8,u+=y[n++]<<g,g+=8),m=C[u&_];;){if(u>>>=B=m>>>24,g-=B,16&(B=m>>>16&255)){if(w=65535&m,g<(B&=15)&&(u+=y[n++]<<g,(g+=8)<B&&(u+=y[n++]<<g,g+=8)),(w+=u&(1<<B)-1)>o){e.msg="invalid distance too far back",r.mode=30;break e}if(u>>>=B,g-=B,w>(B=a-s)){if((B=w-B)>d&&r.sane){e.msg="invalid distance too far back",r.mode=30;break e}if(E=0,Q=f,0===l){if(E+=c-B,B<p){p-=B;do{b[a++]=f[E++];}while(--B);E=a-w,Q=b;}}else if(l<B){if(E+=c+l-B,(B-=l)<p){p-=B;do{b[a++]=f[E++];}while(--B);if(E=0,l<p){p-=B=l;do{b[a++]=f[E++];}while(--B);E=a-w,Q=b;}}}else if(E+=l-B,B<p){p-=B;do{b[a++]=f[E++];}while(--B);E=a-w,Q=b;}for(;p>2;)b[a++]=Q[E++],b[a++]=Q[E++],b[a++]=Q[E++],p-=3;p&&(b[a++]=Q[E++],p>1&&(b[a++]=Q[E++]));}else {E=a-w;do{b[a++]=b[E++],b[a++]=b[E++],b[a++]=b[E++],p-=3;}while(p>2);p&&(b[a++]=b[E++],p>1&&(b[a++]=b[E++]));}break}if(64&B){e.msg="invalid distance code",r.mode=30;break e}m=C[(65535&m)+(u&(1<<B)-1)];}}break}}while(n<i&&a<A);n-=p=g>>3,u&=(1<<(g-=p<<3))-1,e.next_in=n,e.next_out=a,e.avail_in=n<i?i-n+5:5-(n-i),e.avail_out=a<A?A-a+257:257-(a-A),r.hold=u,r.bits=g;};},7392:e=>{class t{constructor(e={}){if(!(e.maxSize&&e.maxSize>0))throw new TypeError("`maxSize` must be a number greater than 0");this.maxSize=e.maxSize,this.cache=new Map,this.oldCache=new Map,this._size=0;}_set(e,t){this.cache.set(e,t),this._size++,this._size>=this.maxSize&&(this._size=0,this.oldCache=this.cache,this.cache=new Map);}get(e){if(this.cache.has(e))return this.cache.get(e);if(this.oldCache.has(e)){const t=this.oldCache.get(e);return this.oldCache.delete(e),this._set(e,t),t}}set(e,t){return this.cache.has(e)?this.cache.set(e,t):this._set(e,t),this}has(e){return this.cache.has(e)||this.oldCache.has(e)}peek(e){return this.cache.has(e)?this.cache.get(e):this.oldCache.has(e)?this.oldCache.get(e):void 0}delete(e){const t=this.cache.delete(e);return t&&this._size--,this.oldCache.delete(e)||t}clear(){this.cache.clear(),this.oldCache.clear(),this._size=0;}*keys(){for(const[e]of this)yield e;}*values(){for(const[,e]of this)yield e;}*[Symbol.iterator](){for(const e of this.cache)yield e;for(const e of this.oldCache){const[t]=e;this.cache.has(t)||(yield e);}}get size(){let e=0;for(const t of this.oldCache.keys())this.cache.has(t)||e++;return this._size+e}}e.exports=t;},7414:e=>{e.exports=function(){this.text=0,this.time=0,this.xflags=0,this.os=0,this.extra=null,this.extra_len=0,this.name="",this.comment="",this.hcrc=0,this.done=!1;};},7480:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.MateFlagsDecoder=t.CramFlagsDecoder=t.BamFlagsDecoder=t.MateFlags=t.CramFlags=t.BamFlags=void 0;const i=n(r(588)),a={a:0,A:0,c:1,C:1,g:2,G:2,t:3,T:3,n:4,N:4};function s(e){const t={};for(const[r,n]of e)t[`is${n}`]=e=>!!(e&r),t[`set${n}`]=e=>e|r;return t}t.BamFlags=[[1,"Paired"],[2,"ProperlyPaired"],[4,"SegmentUnmapped"],[8,"MateUnmapped"],[16,"ReverseComplemented"],[32,"MateReverseComplemented"],[64,"Read1"],[128,"Read2"],[256,"Secondary"],[512,"FailedQc"],[1024,"Duplicate"],[2048,"Supplementary"]],t.CramFlags=[[1,"PreservingQualityScores"],[2,"Detached"],[4,"WithMateDownstream"],[8,"DecodeSequenceAsStar"]],t.MateFlags=[[1,"OnNegativeStrand"],[2,"Unmapped"]],t.BamFlagsDecoder=s(t.BamFlags),t.CramFlagsDecoder=s(t.CramFlags),t.MateFlagsDecoder=s(t.MateFlags),t.default=class{constructor({flags:e,cramFlags:t,readLength:r,mappingQuality:n,lengthOnRef:i,qualityScores:a,mateRecordNumber:s,readBases:A,readFeatures:o,mateToUse:c,readGroupId:d,readName:l,sequenceId:f,uniqueId:u,templateSize:g,alignmentStart:h,tags:C}){this.flags=e,this.cramFlags=t,this.readLength=r,this.mappingQuality=n,this.lengthOnRef=i,this.qualityScores=a,A&&(this.readBases=A),this.readGroupId=d,this.readName=l,this.sequenceId=f,this.uniqueId=u,this.templateSize=g,this.alignmentStart=h,this.tags=C,o&&(this.readFeatures=o),c&&(this.mate={flags:c.mateFlags,readName:c.mateReadName,sequenceId:c.mateSequenceId,alignmentStart:c.mateAlignmentStart}),s&&(this.mateRecordNumber=s);}isPaired(){return !!(this.flags&i.default.BAM_FPAIRED)}isProperlyPaired(){return !!(this.flags&i.default.BAM_FPROPER_PAIR)}isSegmentUnmapped(){return !!(this.flags&i.default.BAM_FUNMAP)}isMateUnmapped(){return !!(this.flags&i.default.BAM_FMUNMAP)}isReverseComplemented(){return !!(this.flags&i.default.BAM_FREVERSE)}isMateReverseComplemented(){return !!(this.flags&i.default.BAM_FMREVERSE)}isRead1(){return !!(this.flags&i.default.BAM_FREAD1)}isRead2(){return !!(this.flags&i.default.BAM_FREAD2)}isSecondary(){return !!(this.flags&i.default.BAM_FSECONDARY)}isFailedQc(){return !!(this.flags&i.default.BAM_FQCFAIL)}isDuplicate(){return !!(this.flags&i.default.BAM_FDUP)}isSupplementary(){return !!(this.flags&i.default.BAM_FSUPPLEMENTARY)}isDetached(){return !!(this.cramFlags&i.default.CRAM_FLAG_DETACHED)}hasMateDownStream(){return !!(this.cramFlags&i.default.CRAM_FLAG_MATE_DOWNSTREAM)}isPreservingQualityScores(){return !!(this.cramFlags&i.default.CRAM_FLAG_PRESERVE_QUAL_SCORES)}isUnknownBases(){return !!(this.cramFlags&i.default.CRAM_FLAG_NO_SEQ)}getReadBases(){if(!this.readBases&&this._refRegion){const e=function(e,t){if(!e.lengthOnRef&&!e.readLength)return null;if(e.isUnknownBases())return null;const r=e.alignmentStart-t.start;if(!e.readFeatures)return t.seq.slice(r,r+(e.lengthOnRef||0)).toUpperCase();let n="",i=r,a=0;for(;n.length<e.readLength;)if(a<e.readFeatures.length){const r=e.readFeatures[a];if("Q"===r.code||"q"===r.code)a+=1;else if(r.pos===n.length+1)if(a+=1,"b"===r.code){const e=r.data;n+=e,i+=e.length;}else "B"===r.code?(n+=r.data[0],i+=1):"X"===r.code?(n+=r.sub,i+=1):"I"===r.code?n+=r.data:"D"===r.code?i+=r.data:"i"===r.code?n+=r.data:"N"===r.code?i+=r.data:"S"===r.code?n+=r.data:"P"===r.code||r.code;else if(a<e.readFeatures.length){const e=t.seq.slice(i,i+r.pos-n.length-1);n+=e,i+=e.length;}}else {const r=t.seq.slice(i,i+e.readLength-n.length);n+=r,i+=r.length;}return n.toUpperCase()}(this,this._refRegion);e&&(this.readBases=e);}return this.readBases}getPairOrientation(){if(!this.isSegmentUnmapped()&&this.isPaired()&&!this.isMateUnmapped()&&this.mate&&this.sequenceId===this.mate.sequenceId){const e=this.isReverseComplemented()?"R":"F",t=this.isMateReverseComplemented()?"R":"F";let r=" ",n=" ";this.isRead1()?(r="1",n="2"):this.isRead2()&&(r="2",n="1");const i=[];let a=this.templateLength||this.templateSize;if(void 0===a)throw new Error("One of templateSize and templateLength must be set");return this.alignmentStart>this.mate.alignmentStart&&a>0&&(a=-a),a>0?(i[0]=e,i[1]=r,i[2]=t,i[3]=n):(i[2]=e,i[3]=r,i[0]=t,i[1]=n),i.join("")}return null}addReferenceSequence(e,t){this.readFeatures&&this.readFeatures.forEach((r=>{"X"===r.code&&function(e,t,r,n){const i=n.refPos-t.start,s=t.seq.charAt(i);s&&(n.ref=s);let A=a[s];void 0===A&&(A=4);const o=r.substitutionMatrix[A][n.data];o&&(n.sub=o);}(0,e,t,r);})),!this.readBases&&e.start<=this.alignmentStart&&e.end>=this.alignmentStart+(this.lengthOnRef||this.readLength)-1&&(this._refRegion=e);}toJSON(){const e={};return Object.keys(this).forEach((t=>{t.startsWith("_")||(e[t]=this[t]);})),e.readBases=this.getReadBases(),e}};},7580:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.cramFileDefinition=i,t.cramBlockHeader=a,t.cramBlockCrc32=s,t.cramTagDictionary=o,t.cramPreservationMap=c,t.isMappedSliceHeader=function(e){return "number"==typeof e.refSeqId},t.getSectionParsers=function(e){return {cramFileDefinition:i(),cramBlockHeader:a(),cramBlockCrc32:s(),cramDataSeriesEncodingMap:g(),cramTagEncodingMap:h(),cramCompressionHeader:{parser:(e,t)=>{const{value:r,offset:n}=c().parser(e,t);t=n;const{value:i,offset:a}=g().parser(e,t);t=a;const{value:s,offset:A}=h().parser(e,t);return t=A,{value:{dataSeriesEncoding:d(i),preservation:d(r),tagEncoding:d(s)},offset:t}}},cramEncoding:{parser:(e,t)=>u(e,t)},cramUnmappedSliceHeader:l(e),cramMappedSliceHeader:f(e),cramContainerHeader1:C(e),cramContainerHeader2:I(e)}};const n=r(2549);function i(){return {parser:(e,t=0)=>{const r=new DataView(e.buffer,e.byteOffset,e.length),n=new TextDecoder("utf8");let i=0;const a=n.decode(e.subarray(i,i+4));i+=4;const s=r.getUint8(i);i+=1;const A=r.getUint8(i);i+=1;const o=n.decode(e.subarray(i,i+20)).replaceAll("\0","");return i+=20,{value:{magic:a,majorVersion:s,minorVersion:A,fileId:o},offset:i}},maxLength:26}}function a(){return {parser:(e,t=0)=>{const r=e,i=new DataView(r.buffer,r.byteOffset,r.length);let a=0;const s=i.getUint8(a),A=["raw","gzip","bzip2","lzma","rans","rans4x16","arith","fqzcomp","tok3"][s];if(!A)throw new Error(`compression method number ${s} not implemented`);a+=1;const o=i.getUint8(a),c=["FILE_HEADER","COMPRESSION_HEADER","MAPPED_SLICE_HEADER","UNMAPPED_SLICE_HEADER","EXTERNAL_DATA","CORE_DATA"][o];if(!c)throw new Error(`invalid block content type id ${o}`);a+=1;const[d,l]=(0, n.parseItf8)(e,a);a+=l;const[f,u]=(0, n.parseItf8)(e,a);a+=u;const[g,h]=(0, n.parseItf8)(e,a);return a+=h,{offset:a,value:{uncompressedSize:g,compressedSize:f,contentId:d,contentType:c,compressionMethod:A}}},maxLength:17}}function s(){return {parser:(e,t)=>{const r=e,n=new DataView(r.buffer,r.byteOffset,r.length).getUint32(t,!0);return {offset:t+=4,value:{crc32:n}}},maxLength:4}}function A(e,t,r){const n=new TextDecoder("utf8").decode(e.subarray(t,r)),i=[];for(let e=0;e<n.length;e+=3)i.push(n.slice(e,e+3));return i}function o(){return {parser:(e,t)=>{const[r,i]=(0, n.parseItf8)(e,t);t+=i;const a=e.subarray(t,t+r);t+=r;const s=[];let o=0,c=0;for(;c<a.length;c++)a[c]||(s.push(A(a,o,c)),o=c+1);return c>o&&s.push(A(a,o,c)),{value:{size:r,ents:s},offset:t}}}}function c(){return {parser:(e,t)=>{const r=e,i=new DataView(r.buffer,r.byteOffset,r.length),[a,s]=(0, n.parseItf8)(e,t);t+=s;const[A,c]=(0, n.parseItf8)(e,t);t+=c;const d=[];for(let r=0;r<A;r++){const r=String.fromCharCode(e[t])+String.fromCharCode(e[t+1]);if(t+=2,"MI"===r||"UI"===r||"PI"===r||"RN"===r||"AP"===r||"RR"===r)d.push({key:r,value:!!i.getUint8(t)}),t+=1;else if("SM"===r)d.push({key:r,value:[i.getUint8(t),i.getUint8(t+1),i.getUint8(t+2),i.getUint8(t+3),i.getUint8(t+4)]}),t+=5;else {if("TD"!==r)throw new Error(`unknown key ${r}`);{const{offset:n,value:i}=o().parser(e,t);d.push({key:r,value:i.ents}),t=n;}}}return {value:{mapSize:a,mapCount:A,ents:d},offset:t}}}}function d(e){const t={};for(const{key:r,value:n}of e.ents)t[r]&&console.warn(`duplicate key ${r} in map`),t[r]=n;return t}function l(e){return {parser:(t,r)=>{const[i,a]=(0, n.parseItf8)(t,r);r+=a;let s=0;if(e>=3){const[e,i]=(0, n.parseLtf8)(t,r);r+=i,s=e;}else if(2===e){const[e,i]=(0, n.parseItf8)(t,r);r+=i,s=e;}else console.warn("recordCounter=0");const[A,o]=(0, n.parseItf8)(t,r);r+=o;const[c,d]=(0, n.parseItf8)(t,r);r+=d;const l=[];for(let e=0;e<c;e++){const[e,i]=(0, n.parseItf8)(t,r);r+=i,l.push(e);}let f;return e>=2&&(f=[...t.subarray(r,r+16)],r+=16),{value:{recordCounter:s,md5:f,contentIds:l,numContentIds:c,numBlocks:A,numRecords:i},offset:r}},maxLength:e=>40+5*e}}function f(e){return {parser:(t,r)=>{const[i,a]=(0, n.parseItf8)(t,r);r+=a;const[s,A]=(0, n.parseItf8)(t,r);r+=A;const[o,c]=(0, n.parseItf8)(t,r);r+=c;const[d,l]=(0, n.parseItf8)(t,r);r+=l;let f=0;if(e>=3){const[e,i]=(0, n.parseLtf8)(t,r);r+=i,f=e;}else if(2===e){const[e,i]=(0, n.parseItf8)(t,r);r+=i,f=e;}else console.warn("majorVersion is <2, recordCounter set to 0");const[u,g]=(0, n.parseItf8)(t,r);r+=g;const[h,C]=(0, n.parseItf8)(t,r);r+=C;const I=[];for(let e=0;e<h;e++){const[e,i]=(0, n.parseItf8)(t,r);r+=i,I.push(e);}const[_,m]=(0, n.parseItf8)(t,r);let B;return r+=m,e>=2&&(B=[...t.subarray(r,r+16)],r+=16),{value:{md5:B,numBlocks:u,numRecords:d,numContentIds:h,refSeqSpan:o,refSeqId:i,refSeqStart:s,recordCounter:f,refBaseBlockId:_,contentIds:I},offset:r}},maxLength:e=>60+5*e}}function u(e,t){const r=e,i=new DataView(r.buffer,r.byteOffset,r.length),[a,s]=(0, n.parseItf8)(e,t);t+=s;const[A,o]=(0, n.parseItf8)(e,t);t+=o;const c={};if(0===a);else if(1===a){const[r,i]=(0, n.parseItf8)(e,t);c.blockContentId=r,t+=i;}else if(2===a){const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;const[a,s]=(0, n.parseItf8)(e,t);c.M=a,t+=s;}else if(3===a){const r=(0, n.parseItf8)(e,t),i=r[0];t+=r[1];const a=[];for(let r=0;r<i;r++){const r=(0, n.parseItf8)(e,t);a.push(r[0]),t+=r[1];}c.symbols=a;const s=(0, n.parseItf8)(e,t),A=r[0];c.numLengths=A,c.numCodes=i,c.numLengths=A,t+=s[1];const o=[];for(let r=0;r<A;r++){const r=(0, n.parseItf8)(e,t);t+=r[1],o.push(r[0]);}c.bitLengths=o;}else if(4===a){const{value:r,offset:n}=u(e,t);c.lengthsEncoding=r,t=n;const{value:i,offset:a}=u(e,t);c.valuesEncoding=i,t=a;}else if(5===a){c.stopByte=i.getUint8(t),t+=1;const[r,a]=(0, n.parseItf8)(e,t);c.blockContentId=r,t+=a;}else if(6===a){const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;const[a,s]=(0, n.parseItf8)(e,t);c.length=a,t+=s;}else if(7===a){const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;const[a,s]=(0, n.parseItf8)(e,t);c.K=a,t+=s;}else if(8===a){const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;const[a,s]=(0, n.parseItf8)(e,t);c.log2m=a,t+=s;}else {if(9!==a)throw new Error(`unknown codecId ${a}`);{const[r,i]=(0, n.parseItf8)(e,t);c.offset=r,t+=i;}}return {value:{codecId:a,parametersBytes:A,parameters:c},offset:t}}function g(){return {parser:(e,t)=>{const[r,i]=(0, n.parseItf8)(e,t);t+=i;const[a,s]=(0, n.parseItf8)(e,t);t+=s;const A=[];for(let r=0;r<a;r++){const r=String.fromCharCode(e[t])+String.fromCharCode(e[t+1]);t+=2;const{value:n,offset:i}=u(e,t);t=i,A.push({key:r,value:n});}return {value:{mapSize:r,ents:A,mapCount:a},offset:t}}}}function h(){return {parser:(e,t)=>{const[r,i]=(0, n.parseItf8)(e,t);t+=i;const[a,s]=(0, n.parseItf8)(e,t);t+=s;const A=[];for(let r=0;r<a;r++){const[r,i]=(0, n.parseItf8)(e,t);t+=i;const a=String.fromCharCode(r>>16&255)+String.fromCharCode(r>>8&255)+String.fromCharCode(255&r),{value:s,offset:o}=u(e,t);t=o,A.push({key:a,value:s});}return {value:{mapSize:r,ents:A,mapCount:a},offset:t}}}}function C(e){return {maxLength:52,parser:(t,r)=>{const i=t,a=new DataView(i.buffer,i.byteOffset,i.length).getInt32(r,!0);r+=4;const[s,A]=(0, n.parseItf8)(t,r);r+=A;const[o,c]=(0, n.parseItf8)(t,r);r+=c;const[d,l]=(0, n.parseItf8)(t,r);r+=l;const[f,u]=(0, n.parseItf8)(t,r);r+=u;let g,h=0;if(e>=3){const[e,i]=(0, n.parseLtf8)(t,r);h=e,r+=i;}else if(2===e){const[e,i]=(0, n.parseItf8)(t,r);h=e,r+=i;}else console.warn("setting recordCounter=0");if(e>1){const[e,i]=(0, n.parseLtf8)(t,r);g=e,r+=i;}const[C,I]=(0, n.parseItf8)(t,r);r+=I;const[_,m]=(0, n.parseItf8)(t,r);return {value:{length:a,refSeqId:s,refSeqStart:o,alignmentSpan:d,numBlocks:C,numLandmarks:_,numBases:g,recordCounter:h,numRecords:f},offset:r+=m}}}}function I(e){return {parser:(t,r)=>{const i=t,a=new DataView(i.buffer,i.byteOffset,i.length),[s,A]=(0, n.parseItf8)(t,r);r+=A;const o=[];for(let e=0;e<s;e++){const[e,i]=(0, n.parseItf8)(t,r);r+=i,o.push(e);}let c;return e>=3&&(c=a.getUint32(r,!0),r+=4),{value:{...void 0===c?{}:{crc32:c},numLandmarks:s,landmarks:o},offset:r}},maxLength:e=>5+5*e+4}}},7593:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0});},7934:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(2549);class s extends i.default{constructor(e,t,r){super(e,t),this.instantiateCodec=r;}decode(e,t,r,n){const i=this._getLengthCodec().decode(e,t,r,n)||0,a=this._getDataCodec(),s=new Uint8Array(i);for(let A=0;A<i;A+=1)s[A]=a.decode(e,t,r,n)||0;return s}_getLengthCodec(){const e=this.parameters.lengthsEncoding;return this.instantiateCodec(e,"int")}_getDataCodec(){const e=this.parameters.valuesEncoding;return this.instantiateCodec(e,"byte")}}t.default=s,"_getLengthCodec _getDataCodec".split(" ").forEach((e=>{(0, a.tinyMemoize)(s,e);}));},8006:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(6272),s=r(6761);class A extends i.default{decode(e,t,r,n){const{blockContentId:i}=this.parameters,s=r[i];if(!s)throw new a.CramMalformedError(`no block found with content ID ${i}`);const A=n.externalBlocks.getCursor(i);return this._decodeByteArray(s,A)}_decodeByteArray(e,t){const r=e.content,{stopByte:n}=this.parameters,i=t.bytePosition;let a=t.bytePosition;for(;r[a]!==n&&a<r.length;){if(a===r.length)throw new s.CramBufferOverrunError("byteArrayStop reading beyond length of data buffer?");a+=1;}return t.bytePosition=a+1,r.subarray(i,a)}}t.default=A;},8223:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4997)),a=r(6272);t.default=class{constructor(e){if(this.cram=e.cram??new i.default({url:e.cramUrl,path:e.cramPath,filehandle:e.cramFilehandle,seqFetch:e.seqFetch,checkSequenceMD5:e.checkSequenceMD5,cacheSize:e.cacheSize}),!(this.cram instanceof i.default))throw new Error("invalid arguments: no cramfile");this.index=e.index;}async getRecordsForRange(e,t,r,n={}){if(n.viewAsPairs=n.viewAsPairs||!1,n.pairAcrossChr=n.pairAcrossChr||!1,n.maxInsertSize=n.maxInsertSize||2e5,"string"==typeof e)throw new a.CramUnimplementedError("string sequence names not yet supported");const i=e,s=await this.index.getEntriesForRange(i,t,r),A=await Promise.all(s.map((n=>this.getRecordsInSlice(n,(n=>n.sequenceId===e&&n.alignmentStart<=r&&void 0!==n.lengthOnRef&&n.alignmentStart+n.lengthOnRef-1>=t)))));let o=Array.prototype.concat(...A);if(n.viewAsPairs){const e={},t={};for(const r of o){const n=r.readName;if(void 0===n)throw new Error("readName undefined");const i=r.uniqueId;e[n]||(e[n]=0),e[n]+=1,t[i]=1;}const r={};Object.entries(e).forEach((([e,t])=>{1===t&&(r[e]=!0);}));const a=[];for(const e of o){const t=e.readName;if(void 0===t)throw new Error("readName undefined");if(r[t]&&e.mate&&(e.mate.sequenceId===i||n.pairAcrossChr)&&Math.abs(e.alignmentStart-e.mate.alignmentStart)<n.maxInsertSize){const t=this.index.getEntriesForRange(e.mate.sequenceId,e.mate.alignmentStart,e.mate.alignmentStart+1);a.push(t);}}const s=await Promise.all(a);let A=[];for(const e of s)A.push(...e);A=A.sort(((e,t)=>e.toString().localeCompare(t.toString()))).filter(((e,t,r)=>!t||e.toString()!==r[t-1].toString()));const d=[];for(const e of A){let n=this.cram.featureCache.get(e.toString());n||(n=this.getRecordsInSlice(e,(()=>!0)),this.cram.featureCache.set(e.toString(),n));const i=n.then((e=>{const n=[];for(const i of e){if(void 0===i.readName)throw new Error("readName undefined");r[i.readName]&&!t[i.uniqueId]&&n.push(i);}return n}));d.push(i);}const l=await Promise.all(d);if(l.length){const e=l.reduce(((e,t)=>e.concat(t)));o=o.concat(e);}}return o}getRecordsInSlice({containerStart:e,sliceStart:t,sliceBytes:r},n){return this.cram.getContainerAtPosition(e).getSlice(t,r).getRecords(n)}hasDataForReferenceSequence(e){return this.index.hasDataForReferenceSequence(e)}};},8301:function(e,t,r){var n=this&&this.__createBinding||(Object.create?function(e,t,r,n){void 0===n&&(n=r);var i=Object.getOwnPropertyDescriptor(t,r);i&&!("get"in i?!t.__esModule:i.writable||i.configurable)||(i={enumerable:!0,get:function(){return t[r]}}),Object.defineProperty(e,n,i);}:function(e,t,r,n){void 0===n&&(n=r),e[n]=t[r];}),i=this&&this.__exportStar||function(e,t){for(var r in e)"default"===r||Object.prototype.hasOwnProperty.call(t,r)||n(t,e,r);},a=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.LocalFile=t.RemoteFile=t.BlobFile=void 0,t.fromUrl=o,t.open=function(e,t,r,n={}){if(void 0!==r)return r;if(void 0!==e)return o(e,n);if(void 0!==t)return new s.default(t,n);throw new Error("no url, path, or filehandle provided, cannot open")};const s=a(r(2616)),A=a(r(8485));function o(e,t={}){return new A.default(e,t)}i(r(7593),t);var c=r(1064);Object.defineProperty(t,"BlobFile",{enumerable:!0,get:function(){return a(c).default}});var d=r(8485);Object.defineProperty(t,"RemoteFile",{enumerable:!0,get:function(){return a(d).default}});var l=r(2616);Object.defineProperty(t,"LocalFile",{enumerable:!0,get:function(){return a(l).default}});},8411:(e,t,r)=>{var n,i=r(9805),a=r(3665),s=r(3269),A=r(4823),o=r(4674),c=-2,d=258,l=262,f=103,u=113,g=666;function h(e,t){return e.msg=o[t],t}function C(e){return (e<<1)-(e>4?9:0)}function I(e){for(var t=e.length;--t>=0;)e[t]=0;}function _(e){var t=e.state,r=t.pending;r>e.avail_out&&(r=e.avail_out),0!==r&&(i.arraySet(e.output,t.pending_buf,t.pending_out,r,e.next_out),e.next_out+=r,t.pending_out+=r,e.total_out+=r,e.avail_out-=r,t.pending-=r,0===t.pending&&(t.pending_out=0));}function m(e,t){a._tr_flush_block(e,e.block_start>=0?e.block_start:-1,e.strstart-e.block_start,t),e.block_start=e.strstart,_(e.strm);}function B(e,t){e.pending_buf[e.pending++]=t;}function p(e,t){e.pending_buf[e.pending++]=t>>>8&255,e.pending_buf[e.pending++]=255&t;}function w(e,t,r,n){var a=e.avail_in;return a>n&&(a=n),0===a?0:(e.avail_in-=a,i.arraySet(t,e.input,e.next_in,a,r),1===e.state.wrap?e.adler=s(e.adler,t,a,r):2===e.state.wrap&&(e.adler=A(e.adler,t,a,r)),e.next_in+=a,e.total_in+=a,a)}function E(e,t){var r,n,i=e.max_chain_length,a=e.strstart,s=e.prev_length,A=e.nice_match,o=e.strstart>e.w_size-l?e.strstart-(e.w_size-l):0,c=e.window,f=e.w_mask,u=e.prev,g=e.strstart+d,h=c[a+s-1],C=c[a+s];e.prev_length>=e.good_match&&(i>>=2),A>e.lookahead&&(A=e.lookahead);do{if(c[(r=t)+s]===C&&c[r+s-1]===h&&c[r]===c[a]&&c[++r]===c[a+1]){a+=2,r++;do{}while(c[++a]===c[++r]&&c[++a]===c[++r]&&c[++a]===c[++r]&&c[++a]===c[++r]&&c[++a]===c[++r]&&c[++a]===c[++r]&&c[++a]===c[++r]&&c[++a]===c[++r]&&a<g);if(n=d-(g-a),a=g-d,n>s){if(e.match_start=t,s=n,n>=A)break;h=c[a+s-1],C=c[a+s];}}}while((t=u[t&f])>o&&0!==--i);return s<=e.lookahead?s:e.lookahead}function Q(e){var t,r,n,a,s,A=e.w_size;do{if(a=e.window_size-e.lookahead-e.strstart,e.strstart>=A+(A-l)){i.arraySet(e.window,e.window,A,A,0),e.match_start-=A,e.strstart-=A,e.block_start-=A,t=r=e.hash_size;do{n=e.head[--t],e.head[t]=n>=A?n-A:0;}while(--r);t=r=A;do{n=e.prev[--t],e.prev[t]=n>=A?n-A:0;}while(--r);a+=A;}if(0===e.strm.avail_in)break;if(r=w(e.strm,e.window,e.strstart+e.lookahead,a),e.lookahead+=r,e.lookahead+e.insert>=3)for(s=e.strstart-e.insert,e.ins_h=e.window[s],e.ins_h=(e.ins_h<<e.hash_shift^e.window[s+1])&e.hash_mask;e.insert&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[s+3-1])&e.hash_mask,e.prev[s&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=s,s++,e.insert--,!(e.lookahead+e.insert<3)););}while(e.lookahead<l&&0!==e.strm.avail_in)}function y(e,t){for(var r,n;;){if(e.lookahead<l){if(Q(e),e.lookahead<l&&0===t)return 1;if(0===e.lookahead)break}if(r=0,e.lookahead>=3&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+3-1])&e.hash_mask,r=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart),0!==r&&e.strstart-r<=e.w_size-l&&(e.match_length=E(e,r)),e.match_length>=3)if(n=a._tr_tally(e,e.strstart-e.match_start,e.match_length-3),e.lookahead-=e.match_length,e.match_length<=e.max_lazy_match&&e.lookahead>=3){e.match_length--;do{e.strstart++,e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+3-1])&e.hash_mask,r=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart;}while(0!==--e.match_length);e.strstart++;}else e.strstart+=e.match_length,e.match_length=0,e.ins_h=e.window[e.strstart],e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+1])&e.hash_mask;else n=a._tr_tally(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++;if(n&&(m(e,!1),0===e.strm.avail_out))return 1}return e.insert=e.strstart<2?e.strstart:2,4===t?(m(e,!0),0===e.strm.avail_out?3:4):e.last_lit&&(m(e,!1),0===e.strm.avail_out)?1:2}function b(e,t){for(var r,n,i;;){if(e.lookahead<l){if(Q(e),e.lookahead<l&&0===t)return 1;if(0===e.lookahead)break}if(r=0,e.lookahead>=3&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+3-1])&e.hash_mask,r=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart),e.prev_length=e.match_length,e.prev_match=e.match_start,e.match_length=2,0!==r&&e.prev_length<e.max_lazy_match&&e.strstart-r<=e.w_size-l&&(e.match_length=E(e,r),e.match_length<=5&&(1===e.strategy||3===e.match_length&&e.strstart-e.match_start>4096)&&(e.match_length=2)),e.prev_length>=3&&e.match_length<=e.prev_length){i=e.strstart+e.lookahead-3,n=a._tr_tally(e,e.strstart-1-e.prev_match,e.prev_length-3),e.lookahead-=e.prev_length-1,e.prev_length-=2;do{++e.strstart<=i&&(e.ins_h=(e.ins_h<<e.hash_shift^e.window[e.strstart+3-1])&e.hash_mask,r=e.prev[e.strstart&e.w_mask]=e.head[e.ins_h],e.head[e.ins_h]=e.strstart);}while(0!==--e.prev_length);if(e.match_available=0,e.match_length=2,e.strstart++,n&&(m(e,!1),0===e.strm.avail_out))return 1}else if(e.match_available){if((n=a._tr_tally(e,0,e.window[e.strstart-1]))&&m(e,!1),e.strstart++,e.lookahead--,0===e.strm.avail_out)return 1}else e.match_available=1,e.strstart++,e.lookahead--;}return e.match_available&&(n=a._tr_tally(e,0,e.window[e.strstart-1]),e.match_available=0),e.insert=e.strstart<2?e.strstart:2,4===t?(m(e,!0),0===e.strm.avail_out?3:4):e.last_lit&&(m(e,!1),0===e.strm.avail_out)?1:2}function D(e,t,r,n,i){this.good_length=e,this.max_lazy=t,this.nice_length=r,this.max_chain=n,this.func=i;}function S(){this.strm=null,this.status=0,this.pending_buf=null,this.pending_buf_size=0,this.pending_out=0,this.pending=0,this.wrap=0,this.gzhead=null,this.gzindex=0,this.method=8,this.last_flush=-1,this.w_size=0,this.w_bits=0,this.w_mask=0,this.window=null,this.window_size=0,this.prev=null,this.head=null,this.ins_h=0,this.hash_size=0,this.hash_bits=0,this.hash_mask=0,this.hash_shift=0,this.block_start=0,this.match_length=0,this.prev_match=0,this.match_available=0,this.strstart=0,this.match_start=0,this.lookahead=0,this.prev_length=0,this.max_chain_length=0,this.max_lazy_match=0,this.level=0,this.strategy=0,this.good_match=0,this.nice_match=0,this.dyn_ltree=new i.Buf16(1146),this.dyn_dtree=new i.Buf16(122),this.bl_tree=new i.Buf16(78),I(this.dyn_ltree),I(this.dyn_dtree),I(this.bl_tree),this.l_desc=null,this.d_desc=null,this.bl_desc=null,this.bl_count=new i.Buf16(16),this.heap=new i.Buf16(573),I(this.heap),this.heap_len=0,this.heap_max=0,this.depth=new i.Buf16(573),I(this.depth),this.l_buf=0,this.lit_bufsize=0,this.last_lit=0,this.d_buf=0,this.opt_len=0,this.static_len=0,this.matches=0,this.insert=0,this.bi_buf=0,this.bi_valid=0;}function k(e){var t;return e&&e.state?(e.total_in=e.total_out=0,e.data_type=2,(t=e.state).pending=0,t.pending_out=0,t.wrap<0&&(t.wrap=-t.wrap),t.status=t.wrap?42:u,e.adler=2===t.wrap?0:1,t.last_flush=0,a._tr_init(t),0):h(e,c)}function v(e){var t,r=k(e);return 0===r&&((t=e.state).window_size=2*t.w_size,I(t.head),t.max_lazy_match=n[t.level].max_lazy,t.good_match=n[t.level].good_length,t.nice_match=n[t.level].nice_length,t.max_chain_length=n[t.level].max_chain,t.strstart=0,t.block_start=0,t.lookahead=0,t.insert=0,t.match_length=t.prev_length=2,t.match_available=0,t.ins_h=0),r}function R(e,t,r,n,a,s){if(!e)return c;var A=1;if(-1===t&&(t=6),n<0?(A=0,n=-n):n>15&&(A=2,n-=16),a<1||a>9||8!==r||n<8||n>15||t<0||t>9||s<0||s>4)return h(e,c);8===n&&(n=9);var o=new S;return e.state=o,o.strm=e,o.wrap=A,o.gzhead=null,o.w_bits=n,o.w_size=1<<o.w_bits,o.w_mask=o.w_size-1,o.hash_bits=a+7,o.hash_size=1<<o.hash_bits,o.hash_mask=o.hash_size-1,o.hash_shift=~~((o.hash_bits+3-1)/3),o.window=new i.Buf8(2*o.w_size),o.head=new i.Buf16(o.hash_size),o.prev=new i.Buf16(o.w_size),o.lit_bufsize=1<<a+6,o.pending_buf_size=4*o.lit_bufsize,o.pending_buf=new i.Buf8(o.pending_buf_size),o.d_buf=1*o.lit_bufsize,o.l_buf=3*o.lit_bufsize,o.level=t,o.strategy=s,o.method=r,v(e)}n=[new D(0,0,0,0,(function(e,t){var r=65535;for(r>e.pending_buf_size-5&&(r=e.pending_buf_size-5);;){if(e.lookahead<=1){if(Q(e),0===e.lookahead&&0===t)return 1;if(0===e.lookahead)break}e.strstart+=e.lookahead,e.lookahead=0;var n=e.block_start+r;if((0===e.strstart||e.strstart>=n)&&(e.lookahead=e.strstart-n,e.strstart=n,m(e,!1),0===e.strm.avail_out))return 1;if(e.strstart-e.block_start>=e.w_size-l&&(m(e,!1),0===e.strm.avail_out))return 1}return e.insert=0,4===t?(m(e,!0),0===e.strm.avail_out?3:4):(e.strstart>e.block_start&&(m(e,!1),e.strm.avail_out),1)})),new D(4,4,8,4,y),new D(4,5,16,8,y),new D(4,6,32,32,y),new D(4,4,16,16,b),new D(8,16,32,32,b),new D(8,16,128,128,b),new D(8,32,128,256,b),new D(32,128,258,1024,b),new D(32,258,258,4096,b)],t.deflateInit=function(e,t){return R(e,t,8,15,8,0)},t.deflateInit2=R,t.deflateReset=v,t.deflateResetKeep=k,t.deflateSetHeader=function(e,t){return e&&e.state?2!==e.state.wrap?c:(e.state.gzhead=t,0):c},t.deflate=function(e,t){var r,i,s,o;if(!e||!e.state||t>5||t<0)return e?h(e,c):c;if(i=e.state,!e.output||!e.input&&0!==e.avail_in||i.status===g&&4!==t)return h(e,0===e.avail_out?-5:c);if(i.strm=e,r=i.last_flush,i.last_flush=t,42===i.status)if(2===i.wrap)e.adler=0,B(i,31),B(i,139),B(i,8),i.gzhead?(B(i,(i.gzhead.text?1:0)+(i.gzhead.hcrc?2:0)+(i.gzhead.extra?4:0)+(i.gzhead.name?8:0)+(i.gzhead.comment?16:0)),B(i,255&i.gzhead.time),B(i,i.gzhead.time>>8&255),B(i,i.gzhead.time>>16&255),B(i,i.gzhead.time>>24&255),B(i,9===i.level?2:i.strategy>=2||i.level<2?4:0),B(i,255&i.gzhead.os),i.gzhead.extra&&i.gzhead.extra.length&&(B(i,255&i.gzhead.extra.length),B(i,i.gzhead.extra.length>>8&255)),i.gzhead.hcrc&&(e.adler=A(e.adler,i.pending_buf,i.pending,0)),i.gzindex=0,i.status=69):(B(i,0),B(i,0),B(i,0),B(i,0),B(i,0),B(i,9===i.level?2:i.strategy>=2||i.level<2?4:0),B(i,3),i.status=u);else {var l=8+(i.w_bits-8<<4)<<8;l|=(i.strategy>=2||i.level<2?0:i.level<6?1:6===i.level?2:3)<<6,0!==i.strstart&&(l|=32),l+=31-l%31,i.status=u,p(i,l),0!==i.strstart&&(p(i,e.adler>>>16),p(i,65535&e.adler)),e.adler=1;}if(69===i.status)if(i.gzhead.extra){for(s=i.pending;i.gzindex<(65535&i.gzhead.extra.length)&&(i.pending!==i.pending_buf_size||(i.gzhead.hcrc&&i.pending>s&&(e.adler=A(e.adler,i.pending_buf,i.pending-s,s)),_(e),s=i.pending,i.pending!==i.pending_buf_size));)B(i,255&i.gzhead.extra[i.gzindex]),i.gzindex++;i.gzhead.hcrc&&i.pending>s&&(e.adler=A(e.adler,i.pending_buf,i.pending-s,s)),i.gzindex===i.gzhead.extra.length&&(i.gzindex=0,i.status=73);}else i.status=73;if(73===i.status)if(i.gzhead.name){s=i.pending;do{if(i.pending===i.pending_buf_size&&(i.gzhead.hcrc&&i.pending>s&&(e.adler=A(e.adler,i.pending_buf,i.pending-s,s)),_(e),s=i.pending,i.pending===i.pending_buf_size)){o=1;break}o=i.gzindex<i.gzhead.name.length?255&i.gzhead.name.charCodeAt(i.gzindex++):0,B(i,o);}while(0!==o);i.gzhead.hcrc&&i.pending>s&&(e.adler=A(e.adler,i.pending_buf,i.pending-s,s)),0===o&&(i.gzindex=0,i.status=91);}else i.status=91;if(91===i.status)if(i.gzhead.comment){s=i.pending;do{if(i.pending===i.pending_buf_size&&(i.gzhead.hcrc&&i.pending>s&&(e.adler=A(e.adler,i.pending_buf,i.pending-s,s)),_(e),s=i.pending,i.pending===i.pending_buf_size)){o=1;break}o=i.gzindex<i.gzhead.comment.length?255&i.gzhead.comment.charCodeAt(i.gzindex++):0,B(i,o);}while(0!==o);i.gzhead.hcrc&&i.pending>s&&(e.adler=A(e.adler,i.pending_buf,i.pending-s,s)),0===o&&(i.status=f);}else i.status=f;if(i.status===f&&(i.gzhead.hcrc?(i.pending+2>i.pending_buf_size&&_(e),i.pending+2<=i.pending_buf_size&&(B(i,255&e.adler),B(i,e.adler>>8&255),e.adler=0,i.status=u)):i.status=u),0!==i.pending){if(_(e),0===e.avail_out)return i.last_flush=-1,0}else if(0===e.avail_in&&C(t)<=C(r)&&4!==t)return h(e,-5);if(i.status===g&&0!==e.avail_in)return h(e,-5);if(0!==e.avail_in||0!==i.lookahead||0!==t&&i.status!==g){var w=2===i.strategy?function(e,t){for(var r;;){if(0===e.lookahead&&(Q(e),0===e.lookahead)){if(0===t)return 1;break}if(e.match_length=0,r=a._tr_tally(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++,r&&(m(e,!1),0===e.strm.avail_out))return 1}return e.insert=0,4===t?(m(e,!0),0===e.strm.avail_out?3:4):e.last_lit&&(m(e,!1),0===e.strm.avail_out)?1:2}(i,t):3===i.strategy?function(e,t){for(var r,n,i,s,A=e.window;;){if(e.lookahead<=d){if(Q(e),e.lookahead<=d&&0===t)return 1;if(0===e.lookahead)break}if(e.match_length=0,e.lookahead>=3&&e.strstart>0&&(n=A[i=e.strstart-1])===A[++i]&&n===A[++i]&&n===A[++i]){s=e.strstart+d;do{}while(n===A[++i]&&n===A[++i]&&n===A[++i]&&n===A[++i]&&n===A[++i]&&n===A[++i]&&n===A[++i]&&n===A[++i]&&i<s);e.match_length=d-(s-i),e.match_length>e.lookahead&&(e.match_length=e.lookahead);}if(e.match_length>=3?(r=a._tr_tally(e,1,e.match_length-3),e.lookahead-=e.match_length,e.strstart+=e.match_length,e.match_length=0):(r=a._tr_tally(e,0,e.window[e.strstart]),e.lookahead--,e.strstart++),r&&(m(e,!1),0===e.strm.avail_out))return 1}return e.insert=0,4===t?(m(e,!0),0===e.strm.avail_out?3:4):e.last_lit&&(m(e,!1),0===e.strm.avail_out)?1:2}(i,t):n[i.level].func(i,t);if(3!==w&&4!==w||(i.status=g),1===w||3===w)return 0===e.avail_out&&(i.last_flush=-1),0;if(2===w&&(1===t?a._tr_align(i):5!==t&&(a._tr_stored_block(i,0,0,!1),3===t&&(I(i.head),0===i.lookahead&&(i.strstart=0,i.block_start=0,i.insert=0))),_(e),0===e.avail_out))return i.last_flush=-1,0}return 4!==t?0:i.wrap<=0?1:(2===i.wrap?(B(i,255&e.adler),B(i,e.adler>>8&255),B(i,e.adler>>16&255),B(i,e.adler>>24&255),B(i,255&e.total_in),B(i,e.total_in>>8&255),B(i,e.total_in>>16&255),B(i,e.total_in>>24&255)):(p(i,e.adler>>>16),p(i,65535&e.adler)),_(e),i.wrap>0&&(i.wrap=-i.wrap),0!==i.pending?0:1)},t.deflateEnd=function(e){var t;return e&&e.state?42!==(t=e.state.status)&&69!==t&&73!==t&&91!==t&&t!==f&&t!==u&&t!==g?h(e,c):(e.state=null,t===u?h(e,-3):0):c},t.deflateSetDictionary=function(e,t){var r,n,a,A,o,d,l,f,u=t.length;if(!e||!e.state)return c;if(2===(A=(r=e.state).wrap)||1===A&&42!==r.status||r.lookahead)return c;for(1===A&&(e.adler=s(e.adler,t,u,0)),r.wrap=0,u>=r.w_size&&(0===A&&(I(r.head),r.strstart=0,r.block_start=0,r.insert=0),f=new i.Buf8(r.w_size),i.arraySet(f,t,u-r.w_size,r.w_size,0),t=f,u=r.w_size),o=e.avail_in,d=e.next_in,l=e.input,e.avail_in=u,e.next_in=0,e.input=t,Q(r);r.lookahead>=3;){n=r.strstart,a=r.lookahead-2;do{r.ins_h=(r.ins_h<<r.hash_shift^r.window[n+3-1])&r.hash_mask,r.prev[n&r.w_mask]=r.head[r.ins_h],r.head[r.ins_h]=n,n++;}while(--a);r.strstart=n,r.lookahead=2,Q(r);}return r.strstart+=r.lookahead,r.block_start=r.strstart,r.insert=r.lookahead,r.lookahead=0,r.match_length=r.prev_length=2,r.match_available=0,e.next_in=d,e.input=l,e.avail_in=o,r.wrap=A,0},t.deflateInfo="pako deflate (from Nodeca project)";},8485:(e,t)=>{function r(e){return ("object"==typeof e&&null!==e&&"message"in e?e.message:`${e}`).replace(/\.$/,"")}Object.defineProperty(t,"__esModule",{value:!0}),t.default=class{constructor(e,t={}){this.baseOverrides={},this.url=e;const r=t.fetch||globalThis.fetch.bind(globalThis);t.overrides&&(this.baseOverrides=t.overrides),this.fetchImplementation=r;}async fetch(e,t){let n;try{n=await this.fetchImplementation(e,t);}catch(i){if(!`${i}`.includes("Failed to fetch"))throw new Error(`${r(i)} fetching ${e}`,{cause:i});console.warn(`generic-filehandle: refetching ${e} to attempt to work around chrome CORS header caching bug`);try{n=await this.fetchImplementation(e,{...t,cache:"reload"});}catch(t){throw new Error(`${r(t)} fetching ${e}`,{cause:t})}}return n}async read(e,t,r={}){const{headers:n={},signal:i,overrides:a={}}=r;e<1/0?n.range=`bytes=${t}-${t+e}`:e===1/0&&0!==t&&(n.range=`bytes=${t}-`);const s=await this.fetch(this.url,{...this.baseOverrides,...a,headers:{...n,...a.headers,...this.baseOverrides.headers},method:"GET",redirect:"follow",mode:"cors",signal:i});if(!s.ok)throw new Error(`HTTP ${s.status} fetching ${this.url}`);if(200===s.status&&0===t||206===s.status){const t=await s.arrayBuffer(),r=s.headers.get("content-range"),n=/\/(\d+)$/.exec(r||"");return n?.[1]&&(this._stat={size:parseInt(n[1],10)}),new Uint8Array(t.slice(0,e))}throw 200===s.status?new Error(`${this.url} fetch returned status 200, expected 206`):new Error(`HTTP ${s.status} fetching ${this.url}`)}async readFile(e={}){let t,r;"string"==typeof e?(t=e,r={}):(t=e.encoding,r=e,delete r.encoding);const{headers:n={},signal:i,overrides:a={}}=r,s=await this.fetch(this.url,{headers:n,method:"GET",redirect:"follow",mode:"cors",signal:i,...this.baseOverrides,...a});if(200!==s.status)throw new Error(`HTTP ${s.status} fetching ${this.url}`);if("utf8"===t)return s.text();if(t)throw new Error(`unsupported encoding: ${t}`);return new Uint8Array(await s.arrayBuffer())}async stat(){if(!this._stat&&(await this.read(10,0),!this._stat))throw new Error(`unable to determine size of file at ${this.url}`);return this._stat}async close(){}};},8594:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.decode=function(e){const t=new i.default(e),r=t.ReadByte(),n=(t.ReadUint32(),t.ReadUint32());return 0==r?function(e,t){const r=new Array(256),n=new Array(256);d(e,r,n);const i=A(n),s=new Array(4);for(var l=0;l<4;l++)s[l]=e.ReadUint32();const f=new Uint8Array(t);for(l=0;l<t;l++){const t=l%4,A=i[a(s[t])];f[l]=A,s[t]=o(s[t],n[A],r[A]),s[t]=c(e,s[t]);}return f}(t,n):function(e,t){const r=new Array(256),n=new Array(256);!function(e,t,r){for(let e=0;e<256;e++){t[e]=new Array(256),r[e]=new Array(256);for(let r=0;r<256;r++)t[e][r]=0;}let n=e.ReadByte(),i=n,a=0;do{d(e,t[n],r[n]),a>0?(a--,n++):(n=e.ReadByte(),n==i+1&&(a=e.ReadByte())),i=n;}while(0!=n)}(e,r,n);const i=new Array(256);for(var l=0;l<256;l++)i[l]=A(n[l]);const f=new Array(4),u=new Array(4);for(var g=0;g<4;g++)f[g]=e.ReadUint32(),u[g]=0;const h=new Uint8Array(t),C=Math.floor(t/4);for(l=0;l<C;l++)for(g=0;g<4;g++){var I=a(f[g]),_=i[u[g]][I];h[l+g*C]=_,f[g]=o(f[g],n[u[g]][_],r[u[g]][_]),f[g]=c(e,f[g]),u[g]=_;}for(l*=4;l<t;)I=a(f[3]),_=s(n[u[3]],I),h[l++]=_,f[3]=o(f[3],n[u[3]][_],r[u[3]][_]),f[3]=c(e,f[3]),u[3]=_;return h}(t,n)};const i=n(r(3088));function a(e){return 4095&e}function s(e,t){let r=0;for(;t>=e[r+1];)r++;return r}function A(e){const t=new Array(4096);let r=0;for(let n=0;n<4096;n++){for(;n>=e[r+1];)r++;t[n]=r;}return t}function o(e,t,r){return r*(e>>12)+(4095&e)-t}function c(e,t){for(;t<1<<23;)t=(t<<8)+e.ReadByte();return t}function d(e,t,r){for(var n=0;n<256;n++)t[n]=0;let i=e.ReadByte(),a=i,s=0;do{const r=e.ReadITF8();t[i]=r,s>0?(s--,i++):(i=e.ReadByte(),i==a+1&&(s=e.ReadByte())),a=i;}while(0!=i);for(r[0]=0,n=0;n<=255;n++)r[n+1]=r[n]+t[n];}},8700:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0});const n=r(6272),i=r(1609),a={BF:"int",CF:"int",RI:"int",RL:"int",AP:"int",RG:"int",MF:"int",NS:"int",NP:"int",TS:"int",NF:"int",TC:"byte",TN:"int",FN:"int",FC:"byte",FP:"int",BS:"byte",IN:"byteArray",SC:"byteArray",DL:"int",BA:"byte",BB:"byteArray",RS:"int",PD:"int",HC:"int",MQ:"int",RN:"byteArray",QS:"byte",QQ:"byteArray",TL:"int"};t.default=class{constructor(e){this.dataSeriesCodecCache={},this.tagCodecCache={},this.tagEncoding={},this.readNamesIncluded=e.preservation.RN,this.APdelta=e.preservation.AP,this.referenceRequired=!!e.preservation.RR,this.tagIdsDictionary=e.preservation.TD,this.substitutionMatrix=function(e){const t=new Array(5);for(let e=0;e<5;e+=1)t[e]=new Array(4);return t[0][e[0]>>6&3]="C",t[0][e[0]>>4&3]="G",t[0][e[0]>>2&3]="T",t[0][3&e[0]]="N",t[1][e[1]>>6&3]="A",t[1][e[1]>>4&3]="G",t[1][e[1]>>2&3]="T",t[1][3&e[1]]="N",t[2][e[2]>>6&3]="A",t[2][e[2]>>4&3]="C",t[2][e[2]>>2&3]="T",t[2][3&e[2]]="N",t[3][e[3]>>6&3]="A",t[3][e[3]>>4&3]="C",t[3][e[3]>>2&3]="G",t[3][3&e[3]]="N",t[4][e[4]>>6&3]="A",t[4][e[4]>>4&3]="C",t[4][e[4]>>2&3]="G",t[4][3&e[4]]="T",t}(e.preservation.SM),this.dataSeriesEncoding=e.dataSeriesEncoding,this.tagEncoding=e.tagEncoding;}getCodecForTag(e){const t=this.tagCodecCache[e];if(t)return t;{const t=this.tagEncoding[e];if(!t)throw new Error("Error, no tag encoding");const r=(0, i.instantiateCodec)(t,"byteArray");return this.tagCodecCache[e]=r,r}}getTagNames(e){return this.tagIdsDictionary[e]}getCodecForDataSeries(e){let t=this.dataSeriesCodecCache[e];if(void 0===t){const r=this.dataSeriesEncoding[e];if(r){const s=a[e];if(!s)throw new n.CramMalformedError(`data series name ${e} not defined in file compression header`);t=(0, i.instantiateCodec)(r,s),this.dataSeriesCodecCache[e]=t;}}return t}toJSON(){const e={};return Object.keys(this).forEach((t=>{t.endsWith("Cache")||(e[t]=this[t]);})),e}};},8751:function(e,t,r){var n,i=this&&this.__createBinding||(Object.create?function(e,t,r,n){void 0===n&&(n=r);var i=Object.getOwnPropertyDescriptor(t,r);i&&!("get"in i?!t.__esModule:i.writable||i.configurable)||(i={enumerable:!0,get:function(){return t[r]}}),Object.defineProperty(e,n,i);}:function(e,t,r,n){void 0===n&&(n=r),e[n]=t[r];}),a=this&&this.__setModuleDefault||(Object.create?function(e,t){Object.defineProperty(e,"default",{enumerable:!0,value:t});}:function(e,t){e.default=t;}),s=this&&this.__importStar||(n=function(e){return n=Object.getOwnPropertyNames||function(e){var t=[];for(var r in e)Object.prototype.hasOwnProperty.call(e,r)&&(t[t.length]=r);return t},n(e)},function(e){if(e&&e.__esModule)return e;var t={};if(null!=e)for(var r=n(e),s=0;s<r.length;s++)"default"!==r[s]&&i(t,e,r[s]);return a(t,e),t}),A=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const o=A(r(86)),c=A(r(7392)),d=r(1307),l=r(6272),f=s(r(4562)),u=r(6727),g=A(r(2670)),h=r(5011),C=r(870),I=r(2169),_=A(r(2845)),m=r(7580),B=r(2549);class p{constructor(e){if(this.file=(0, u.open)(e.url,e.path,e.filehandle),this.validateChecksums=!0,this.fetchReferenceSequenceCallback=e.seqFetch,this.options={checkSequenceMD5:e.checkSequenceMD5,cacheSize:e.cacheSize??2e4},this.featureCache=new c.default({maxSize:this.options.cacheSize}),function(){const e=new Uint32Array([287454020]),t=new Uint8Array(e.buffer);return 68===t[0]?0:17===t[0]?1:2}()>0)throw new Error("Detected big-endian machine, may be unable to run")}read(e,t){return this.file.read(e,t)}async getDefinition(){const{maxLength:e,parser:t}=(0, m.cramFileDefinition)(),r=t(await this.file.read(e,0)).value;if(2!==r.majorVersion&&3!==r.majorVersion)throw new l.CramUnimplementedError(`CRAM version ${r.majorVersion} not supported`);return r}async getSamHeader(){const e=await this.getContainerById(0);if(!e)throw new l.CramMalformedError("file contains no containers");const t=(await e.getFirstBlock()).content,r=new DataView(t.buffer).getInt32(0,!0),n=new TextDecoder("utf8").decode(t.subarray(4,4+r));return this.header=n,(0, h.parseHeaderText)(n)}async getHeaderText(){return await this.getSamHeader(),this.header}async getContainerById(e){const{majorVersion:t}=await this.getDefinition();let r,n=(0, m.getSectionParsers)(t).cramFileDefinition.maxLength;for(let t=0;t<=e;t++){r=this.getContainerAtPosition(n);const e=await r.getHeader();if(0===t){n=e._endPosition;for(let t=0;t<e.numBlocks;t++)n=(await this.readBlock(n))._endPosition;}else n+=e._size+e.length;}return r}async checkCrc32(e,t,r,n){const i=await this.file.read(t,e),a=(0, o.default)(i)>>>0;if(a!==r)throw new l.CramMalformedError(`crc mismatch in ${n}: recorded CRC32 = ${r}, but calculated CRC32 = ${a}`)}async containerCount(){const{majorVersion:e}=await this.getDefinition();let t=0,r=(0, m.getSectionParsers)(e).cramFileDefinition.maxLength;try{for(;;){const e=await this.getContainerAtPosition(r).getHeader();if(0===t){r=e._endPosition;for(let t=0;t<e.numBlocks;t++)r=(await this.readBlock(r))._endPosition;}else r+=e._size+e.length;t+=1;}}catch(e){t--;}return t}getContainerAtPosition(e){return new _.default(this,e)}async readBlockHeader(e){const{majorVersion:t}=await this.getDefinition(),r=(0, m.getSectionParsers)(t),{cramBlockHeader:n}=r,i=await this.file.read(n.maxLength,e);return (0, B.parseItem)(i,n.parser,0,e)}async _parseSection(e,t,r=e.maxLength,n){const i=n??await this.file.read(r,t),a=(0, B.parseItem)(i,e.parser,0,t);if(a._size!==r)throw new l.CramMalformedError(`section read error: requested size ${r} does not equal parsed size ${a._size}`);return a}async _uncompressPre(e,t,r){if("gzip"===e)return (0, I.unzip)(t);if("bzip2"===e)return (0, C.decode)(t);if("lzma"===e){const e=new Response(new d.XzReadableStream((n=t,new ReadableStream({start(e){e.enqueue(n),e.close();}}))));return new Uint8Array(await e.arrayBuffer())}if("rans"===e){const e=new Uint8Array(r);return (0, g.default)(t,e),e}if("rans4x16"===e)return f.r4x16_uncompress(t);if("arith"===e)return f.arith_uncompress(t);if("fqzcomp"===e)return f.fqzcomp_uncompress(t);if("tok3"===e)return f.tok3_uncompress(t);throw new l.CramUnimplementedError(`${e} decompression not yet implemented`);var n;}async _uncompress(e,t,r){const n=await this._uncompressPre(e,t,r);if(n.length!==r){const e=new Uint8Array(r);return e.set(n,0),e}return n}async readBlock(e){const{majorVersion:t}=await this.getDefinition(),r=(0, m.getSectionParsers)(t),n=await this.readBlockHeader(e),i=n._endPosition,a=await this.file.read(n.compressedSize,i),s="raw"!==n.compressionMethod?await this._uncompress(n.compressionMethod,a,n.uncompressedSize):a,A={...n,_endPosition:i,contentPosition:i,content:s};if(t>=3){const t=await this._parseSection(r.cramBlockCrc32,i+n.compressedSize);A.crc32=t.crc32,this.validateChecksums&&await this.checkCrc32(e,n._size+n.compressedSize,t.crc32,"block data"),A._endPosition=t._endPosition,A._size=A.compressedSize+r.cramBlockCrc32.maxLength;}else A._endPosition=i+A.compressedSize,A._size=A.compressedSize;return A}}t.default=p,"getDefinition getSectionParsers getSamHeader".split(" ").forEach((e=>{(0, B.tinyMemoize)(p,e);}));},8761:(e,t)=>{Object.defineProperty(t,"__esModule",{value:!0});const r=new Uint32Array([0,79764919,159529838,222504665,319059676,398814059,445009330,507990021,638119352,583659535,797628118,726387553,890018660,835552979,1015980042,944750013,1276238704,1221641927,1167319070,1095957929,1595256236,1540665371,1452775106,1381403509,1780037320,1859660671,1671105958,1733955601,2031960084,2111593891,1889500026,1952343757,2552477408,2632100695,2443283854,2506133561,2334638140,2414271883,2191915858,2254759653,3190512472,3135915759,3081330742,3009969537,2905550212,2850959411,2762807018,2691435357,3560074640,3505614887,3719321342,3648080713,3342211916,3287746299,3467911202,3396681109,4063920168,4143685023,4223187782,4286162673,3779000052,3858754371,3904687514,3967668269,881225847,809987520,1023691545,969234094,662832811,591600412,771767749,717299826,311336399,374308984,453813921,533576470,25881363,88864420,134795389,214552010,2023205639,2086057648,1897238633,1976864222,1804852699,1867694188,1645340341,1724971778,1587496639,1516133128,1461550545,1406951526,1302016099,1230646740,1142491917,1087903418,2896545431,2825181984,2770861561,2716262478,3215044683,3143675388,3055782693,3001194130,2326604591,2389456536,2200899649,2280525302,2578013683,2640855108,2418763421,2498394922,3769900519,3832873040,3912640137,3992402750,4088425275,4151408268,4197601365,4277358050,3334271071,3263032808,3476998961,3422541446,3585640067,3514407732,3694837229,3640369242,1762451694,1842216281,1619975040,1682949687,2047383090,2127137669,1938468188,2001449195,1325665622,1271206113,1183200824,1111960463,1543535498,1489069629,1434599652,1363369299,622672798,568075817,748617968,677256519,907627842,853037301,1067152940,995781531,51762726,131386257,177728840,240578815,269590778,349224269,429104020,491947555,4046411278,4126034873,4172115296,4234965207,3794477266,3874110821,3953728444,4016571915,3609705398,3555108353,3735388376,3664026991,3290680682,3236090077,3449943556,3378572211,3174993278,3120533705,3032266256,2961025959,2923101090,2868635157,2813903052,2742672763,2604032198,2683796849,2461293480,2524268063,2284983834,2364738477,2175806836,2238787779,1569362073,1498123566,1409854455,1355396672,1317987909,1246755826,1192025387,1137557660,2072149281,2135122070,1912620623,1992383480,1753615357,1816598090,1627664531,1707420964,295390185,358241886,404320391,483945776,43990325,106832002,186451547,266083308,932423249,861060070,1041341759,986742920,613929101,542559546,756411363,701822548,3316196985,3244833742,3425377559,3370778784,3601682597,3530312978,3744426955,3689838204,3819031489,3881883254,3928223919,4007849240,4037393693,4100235434,4180117107,4259748804,2310601993,2373574846,2151335527,2231098320,2596047829,2659030626,2470359227,2550115596,2947551409,2876312838,2788305887,2733848168,3165939309,3094707162,3040238851,2985771188]);t.default=class{constructor(){this.crc=4294967295;}getCRC(){return ~this.crc>>>0}updateCRC(e){this.crc=this.crc<<8^r[255&(this.crc>>>24^e)];}updateCRCRun(e,t){for(;t-- >0;)this.crc=this.crc<<8^r[255&(this.crc>>>24^e)];}};},8930:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=n(r(4141)),a=r(6272),s=r(2549),A=r(6761);class o extends i.default{constructor(e,t){if(super(e,t),"int"===this.dataType)this._decodeData=this._decodeInt;else {if("byte"!==this.dataType)throw new a.CramUnimplementedError(`${this.dataType} decoding not yet implemented by EXTERNAL codec`);this._decodeData=this._decodeByte;}}decode(e,t,r,n){const{blockContentId:i}=this.parameters,a=r[i];return a?this._decodeData(a,n.externalBlocks.getCursor(i)):void 0}_decodeInt(e,t){const[r,n]=(0, s.parseItf8)(e.content,t.bytePosition);return t.bytePosition=t.bytePosition+n,r}_decodeByte(e,t){if(t.bytePosition>=e.content.length)throw new A.CramBufferOverrunError("attempted to read beyond end of block. this file seems truncated.");return e.content[t.bytePosition++]}}t.default=o;},9301:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0});const n=r(6272),i=r(7151);class a{constructor(){this.F=void 0,this.C=void 0;}}function s(e,t,r,n){return r*(e>>n)+(e&(1<<n)-1)-t}t.default={FC:a,AriDecoder:class{constructor(){this.fc=new Array(256);for(let e=0;e<this.fc.length;e+=1)this.fc[e]=new a;this.R=null;}},DecodingSymbol:class{constructor(){this.start=void 0,this.freq=void 0;}},symbolInit:function(e,t,r){if(!(t<=65536))throw new n.CramMalformedError("assertion failed: start <= 1<<16");if(!(r<=65536-t))throw new n.CramMalformedError("assertion failed: freq <= 1<<16");e.start=t,e.freq=r;},advanceStep:s,advanceSymbolStep:function(e,t,r){return s(e,t.start,t.freq,r)},get:function(e,t){return e&(1<<t)-1},advanceSymbol:function(e,t,r,n){return function(e,t,r,n,a){if((e=n*(e>>a)+(e&(1<<a)-1)-r)<i.RANS_BYTE_L)do{e=e<<8|255&t.get();}while(e<i.RANS_BYTE_L);return e}(e,t,r.start,r.freq,n)},renormalize:function(e,t){if(e<i.RANS_BYTE_L)do{e=e<<8|255&t.get();}while(e<i.RANS_BYTE_L);return e}};},9313:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0}),t.decode=function(e){return d(new i.default(e),0)};const i=n(r(3088));function a(e,t){return e&(1<<t)-1}function s(e,t){let r=0;for(;t>=e[r+1];)r++;return r}function A(e,t){const r=1<<t,n=new Array(r);let i=0;for(let t=0;t<r;t++){for(;t>=e[i+1];)i++;n[t]=i;}return n}function o(e,t,r,n){return r*(e>>n)+(e&(1<<n)-1)-t}function c(e,t){return t<32768&&(t=(t<<16)+e.ReadUint16()),t}function d(e,t){const r=e.ReadByte(),n=1&r,g=8&r,h=32&r,C=64&r,I=128&r,_=4&r?32:4;if(16&r||(t=e.ReadUint7()),g)return function(e,t){const r=e.ReadByte(),n=new Array(r),i=new Array(r);for(var a=0;a<r;a++)n[a]=e.ReadUint7();const s=new Array(r);for(a=0;a<r;a++)i[a]=Math.floor(t/r)+(t%r>a),s[a]=d(e,i[a]);const A=new Uint8Array(t);for(a=0;a<r;a++)for(let e=0;e<i[a];e++)A[e*r+a]=s[a][e];return A}(e,t);if(I)var m=t,[B,p,t]=function(e){const t=e.ReadByte(),r=new Array(t);for(let n=0;n<t;n++)r[n]=e.ReadByte();return [r,t,e.ReadUint7()]}(e);if(C)var w=t,[E,Q,t]=function(e,t){const r=e.ReadUint7(),n=e.ReadUint7();if(1&r)var a=e.ReadData((r-1)/2);else {const n=e.ReadUint7();a=e.ReadData(n),a=f(new i.default(a),r/2,t);}a=new i.default(a);const s=new Array(256);let A=a.ReadByte();0==A&&(A=256);for(let e=0;e<A;e++)s[a.ReadByte()]=1;return [s,a,n]}(e,_);if(h)var y=e.ReadData(t);else y=0==n?f(e,t,_):function(e,t,r){const n=(g=e.ReadByte())>>4;var d=e;if(1&g){const t=e.ReadUint7(),r=e.ReadUint7();var g=new i.default(e.ReadData(r));d=new i.default(f(g,t,4));}const h=new Array(256),C=new Array(256);!function(e,t,r,n){for(var i=0;i<256;i++){t[i]=new Array(256),r[i]=new Array(256);for(var a=0;a<256;a++)t[i][a]=0;}const s=l(e);for(i=0;i<256;i++){if(!s[i])continue;let A=0;for(a=0;a<256;a++)s[a]&&(A>0?A--:(t[i][a]=e.ReadUint7(),0==t[i][a]&&(A=e.ReadByte())));for(u(t[i],n),r[i][0]=0,a=0;a<256;a++)r[i][a+1]=r[i][a]+t[i][a];}}(d,h,C,n);const I=new Array(256);for(var _=0;_<256;_++)I[_]=A(C[_],n);const m=new Array(r),B=new Array(r);for(var p=0;p<r;p++)m[p]=e.ReadUint32(),B[p]=0;const w=new Uint8Array(t),E=Math.floor(t/r);for(_=0;_<E;_++)for(p=0;p<r;p++){var Q=a(m[p],n),y=I[B[p]][Q];w[_+p*E]=y,m[p]=o(m[p],C[B[p]][y],h[B[p]][y],n),m[p]=c(e,m[p]),B[p]=y;}for(_*=r;_<t;)Q=a(m[r-1],n),y=s(C[B[r-1]],Q),w[_++]=y,m[r-1]=o(m[r-1],C[B[r-1]][y],h[B[r-1]][y],n),m[r-1]=c(e,m[r-1]),B[r-1]=y;return w}(e,t,_);return C&&(y=function(e,t,r,n){new i.default(e);const a=new Uint8Array(n);let s=0;for(let i=0;s<n;i++){const n=e[i];if(t[n]){const e=r.ReadUint7();for(let t=0;t<=e;t++)a[s++]=n;}else a[s++]=n;}return a}(y,E,Q,w)),I&&(y=function(e,t,r,n){const i=new Uint8Array(n);let a=0;if(r<=1)for(var s=0;s<n;s++)i[s]=t[0];else if(r<=2)for(s=0;s<n;s++){if(s%8==0)var A=e[a++];i[s]=t[1&A],A>>=1;}else if(r<=4)for(s=0;s<n;s++)s%4==0&&(A=e[a++]),i[s]=t[3&A],A>>=2;else if(r<=16)for(s=0;s<n;s++)s%2==0&&(A=e[a++]),i[s]=t[15&A],A>>=4;return i}(y,B,p,m)),y}function l(e){const t=new Array(256);for(let e=0;e<256;e++)t[e]=0;let r=0,n=e.ReadByte(),i=n;do{t[n]=1,r>0?(r--,n++):(n=e.ReadByte(),n==i+1&&(r=e.ReadByte())),i=n;}while(0!=n);return t}function f(e,t,r){const n=new Array(256),i=new Array(256);!function(e,t,r){for(var n=0;n<256;n++)t[n]=0;const i=l(e);for(n=0;n<256;n++)i[n]>0&&(t[n]=e.ReadUint7());for(u(t,12),r[0]=0,n=0;n<=255;n++)r[n+1]=r[n]+t[n];}(e,n,i);const s=A(i,12),d=new Array(r);for(var f=0;f<r;f++)d[f]=e.ReadUint32();const g=new Uint8Array(t);for(f=0;f<t;f++){const t=f&r-1,A=s[a(d[t],12)];g[f]=A,d[t]=o(d[t],i[A],n[A],12),d[t]=c(e,d[t]);}return g}function u(e,t){let r=0;for(var n=0;n<256;n++)r+=e[n];if(0==r||r==1<<t)return;let i=0;for(;r<1<<t;)r*=2,i++;for(n=0;n<256;n++)e[n]<<=i;}},9505:function(e,t,r){var n=this&&this.__importDefault||function(e){return e&&e.__esModule?e:{default:e}};Object.defineProperty(t,"__esModule",{value:!0});const i=r(870),a=n(r(4652)),s=n(r(2324)),A=n(r(3088));t.default=class{decode(e){return this.stream=new A.default(e),this.decodeStream(this.stream)}decodeStream(e,t=0){const r=this.stream.ReadByte();16&r||(t=this.stream.ReadUint7());let n=t;const i=1&r;if(8&r)return this.decodeStripe(this.stream,t);var a;if(128&r&&([a,n]=this.decodePackMeta(this.stream)),32&r)var s=this.decodeCat(this.stream,n);else s=4&r?this.decodeExt(this.stream,n):64&r?i?this.decodeRLE1(this.stream,n):this.decodeRLE0(this.stream,n):i?this.decode1(this.stream,n):this.decode0(this.stream,n);return 128&r&&(s=this.decodePack(s,a,t)),s}decode0(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new s.default(n),A=new a.default(e);A.RangeStartDecode(e);for(let n=0;n<t;n++)r[n]=i.ModelDecode(e,A);return r}decode1(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new Array(n);for(var A=0;A<n;A++)i[A]=new s.default(n);const o=new a.default(e);o.RangeStartDecode(e);let c=0;for(A=0;A<t;A++)r[A]=i[c].ModelDecode(e,o),c=r[A];return r}decodeExt(e,t){return (0, i.decode)(e.buf.slice(e.pos))}decodeRLE0(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new s.default(n),A=new Array(258);for(var o=0;o<=257;o++)A[o]=new s.default(4);const c=new a.default(e);for(c.RangeStartDecode(e),o=0;o<t;){r[o]=i.ModelDecode(e,c);let t=A[r[o]].ModelDecode(e,c),n=t,a=256;for(;3==t;)t=A[a].ModelDecode(e,c),a=257,n+=t;for(let e=1;e<=n;e++)r[o+e]=r[o];o+=n+1;}return r}decodeRLE1(e,t){const r=new Uint8Array(t);let n=e.ReadByte();0==n&&(n=256);const i=new Array(n);for(var A=0;A<n;A++)i[A]=new s.default(n);const o=new Array(258);for(A=0;A<=257;A++)o[A]=new s.default(4);const c=new a.default(e);c.RangeStartDecode(e);let d=0;for(A=0;A<t;){r[A]=i[d].ModelDecode(e,c),d=r[A];let t=o[r[A]].ModelDecode(e,c),n=t,a=256;for(;3==t;)t=o[a].ModelDecode(e,c),a=257,n+=t;for(let e=1;e<=n;e++)r[A+e]=r[A];A+=n+1;}return r}decodePackMeta(e){this.nsym=e.ReadByte();const t=new Array(this.nsym);for(let r=0;r<this.nsym;r++)t[r]=e.ReadByte();return [t,e.ReadUint7()]}decodePack(e,t,r){const n=new Uint8Array(r);if(this.nsym<=1)for(var i=0;i<r;i++)n[i]=t[0];else if(this.nsym<=2){i=0;for(var a=0;i<r;i++){if(i%8==0)var s=e[a++];n[i]=t[1&s],s>>=1;}}else if(this.nsym<=4)for(i=0,a=0;i<r;i++)i%4==0&&(s=e[a++]),n[i]=t[3&s],s>>=2;else {if(!(this.nsym<=16))return e;for(i=0,a=0;i<r;i++)i%2==0&&(s=e[a++]),n[i]=t[15&s],s>>=4;}return n}packMeta(e){const t=new A.default("",0,1024),r=new Array(256);for(var n=0;n<e.length;n++)r[e[n]]=1;var i=0;for(n=0;n<256;n++)r[n]&&(r[n]=++i);for(t.WriteByte(i),n=0;n<256;n++)r[n]&&(t.WriteByte(n),r[n]--);return [t,r,i]}decodeStripe(e,t){const r=e.ReadByte(),n=new Array(r),i=new Array(r);for(var a=0;a<r;a++)n[a]=e.ReadUint7();const s=new Array(r);for(a=0;a<r;a++)i[a]=Math.floor(t/r)+(t%r>a),s[a]=this.decodeStream(e,i[a]);const A=new Uint8Array(t);for(a=0;a<r;a++)for(let e=0;e<i[a];e++)A[e*r+a]=s[a][e];return A}decodeCat(e,t){const r=new Uint8Array(t);for(let n=0;n<t;n++)r[n]=e.ReadByte();return r}};},9681:e=>{e.exports={Z_NO_FLUSH:0,Z_PARTIAL_FLUSH:1,Z_SYNC_FLUSH:2,Z_FULL_FLUSH:3,Z_FINISH:4,Z_BLOCK:5,Z_TREES:6,Z_OK:0,Z_STREAM_END:1,Z_NEED_DICT:2,Z_ERRNO:-1,Z_STREAM_ERROR:-2,Z_DATA_ERROR:-3,Z_BUF_ERROR:-5,Z_NO_COMPRESSION:0,Z_BEST_SPEED:1,Z_BEST_COMPRESSION:9,Z_DEFAULT_COMPRESSION:-1,Z_FILTERED:1,Z_HUFFMAN_ONLY:2,Z_RLE:3,Z_FIXED:4,Z_DEFAULT_STRATEGY:0,Z_BINARY:0,Z_TEXT:1,Z_UNKNOWN:2,Z_DEFLATED:8};},9685:(e,t,r)=>{Object.defineProperty(t,"__esModule",{value:!0}),t.default=function(e,t,r,o,c,d,l,f,u){let g=t("BF");const h=t("CF");if(!(0, a.isMappedSliceHeader)(o.parsedContent))throw new Error("slice header not mapped");const C=f>1&&-2===o.parsedContent.refSeqId?t("RI"):o.parsedContent.refSeqId,I=t("RL");let _=t("AP");r.APdelta&&(_+=l.lastAlignmentStart),l.lastAlignmentStart=_;const m=t("RG");let B,p,w,E;if(r.readNamesIncluded&&(B=s(t("RN"))),i.CramFlagsDecoder.isDetached(h)){const e=t("MF");let n;r.readNamesIncluded||(n=s(t("RN")),B=n);const a=t("NS"),A=t("NP");(e||a>-1)&&(p={mateFlags:e,mateSequenceId:a,mateAlignmentStart:A,mateReadName:n}),w=t("TS"),i.MateFlagsDecoder.isUnmapped(e)&&(g=i.BamFlagsDecoder.setMateUnmapped(g)),i.MateFlagsDecoder.isOnNegativeStrand(e)&&(g=i.BamFlagsDecoder.setMateReverseComplemented(g));}else i.CramFlagsDecoder.isWithMateDownstream(h)&&(E=t("NF")+u+1);const Q=t("TL");if(Q<0)throw new n.CramMalformedError("invalid TL index");const y={},b=r.getTagNames(Q),D=b.length;for(let t=0;t<D;t++){const n=b[t],i=n.slice(0,2),a=n.slice(2,3),s=r.getCodecForTag(n).decode(e,c,d,l);y[i]=void 0===s?void 0:"number"==typeof s?s:A(a,s);}let S,k,v,R,F;if(i.BamFlagsDecoder.isSegmentUnmapped(g))if(i.CramFlagsDecoder.isDecodeSequenceAsStar(h))F=null,R=null;else {const e=new Array(I);for(let r=0;r<e.length;r++)e[r]=t("BA");if(F=String.fromCharCode(...e),i.CramFlagsDecoder.isPreservingQualityScores(h)){R=new Array(I);for(let r=0;r<e.length;r++)R[r]=t("QS");}}else {const e=t("FN");if(e&&(S=function(e,t,r,i,a){let s=0,A=e-1;const o=new Array(t);function c([e,t]){const n=r(t);if("character"===e)return String.fromCharCode(n);if("string"===e){let e="";for(let t=0;t<n.byteLength;t++)e+=String.fromCharCode(n[t]);return e}return "numArray"===e?Array.from(n):n}for(let e=0;e<t;e++){const t=String.fromCharCode(r("FC")),i=r("FP"),d={B:["character","BA"],S:["string",a>1?"SC":"IN"],X:["number","BS"],D:["number","DL"],I:["string","IN"],i:["character","BA"],b:["string","BB"],q:["numArray","QQ"],Q:["number","QS"],H:["number","HC"],P:["number","PD"],N:["number","RS"]}[t];if(!d)throw new n.CramMalformedError(`invalid read feature code "${t}"`);let l=c(d);const f={B:["number","QS"]}[t];f&&(l=[l,c(f)]),s+=i;const u=s;A+=i;const g=A;"D"===t||"N"===t?A+=l:"I"===t||"S"===t?A-=l.length:"i"===t&&(A-=1),o[e]={code:t,pos:u,refPos:g,data:l};}return o}(_,e,t,0,f)),k=I,S)for(const{code:e,data:t}of S)"D"===e||"N"===e?k+=t:"I"===e||"S"===e?k-=t.length:"i"===e&&(k-=1);if(Number.isNaN(k)&&(console.warn(`${B||`${C}:${_}`} record has invalid read features`),k=I),v=t("MQ"),i.CramFlagsDecoder.isPreservingQualityScores(h)){R=new Array(I);for(let e=0;e<R.length;e++)R[e]=t("QS");}}return {readLength:I,sequenceId:C,cramFlags:h,flags:g,alignmentStart:_,readGroupId:m,readName:B,mateToUse:p,templateSize:w,mateRecordNumber:E,readFeatures:S,lengthOnRef:k,mappingQuality:v,qualityScores:R,readBases:F,tags:y}};const n=r(6272),i=r(7480),a=r(7580);function s(e){let t="";for(let r=0;r<e.length&&0!==e[r];r++)t+=String.fromCharCode(e[r]);return t}function A(e,t){if("Z"===e)return s(t);if("A"===e)return String.fromCharCode(t[0]);if("I"===e)return new Uint32Array(t.buffer)[0];if("i"===e)return new Int32Array(t.buffer)[0];if("s"===e)return new Int16Array(t.buffer)[0];if("S"===e)return new Uint16Array(t.buffer)[0];if("c"===e)return new Int8Array(t.buffer)[0];if("C"===e)return t[0];if("f"===e)return new Float32Array(t.buffer)[0];if("H"===e)return Number.parseInt(s(t).replace(/^0x/,""),16);if("B"===e)return function(e){const t=String.fromCharCode(e[0]),r=new DataView(e.buffer).getUint32(1,!0),n=new Array(r);if(e=e.slice(5),"c"===t){const t=new Int8Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e];}else if("C"===t){const t=new Uint8Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e];}else if("s"===t){const t=new Int16Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e];}else if("S"===t){const t=new Uint16Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e];}else if("i"===t){const t=new Int32Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e];}else if("I"===t){const t=new Uint32Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e];}else {if("f"!==t)throw new Error(`unknown type: ${t}`);{const t=new Float32Array(e.buffer);for(let e=0;e<r;e++)n[e]=t[e];}}return n}(t);throw new n.CramMalformedError(`Unrecognized tag type ${e}`)}},9805:(e,t)=>{var r="undefined"!=typeof Uint8Array&&"undefined"!=typeof Uint16Array&&"undefined"!=typeof Int32Array;function n(e,t){return Object.prototype.hasOwnProperty.call(e,t)}t.assign=function(e){for(var t=Array.prototype.slice.call(arguments,1);t.length;){var r=t.shift();if(r){if("object"!=typeof r)throw new TypeError(r+"must be non-object");for(var i in r)n(r,i)&&(e[i]=r[i]);}}return e},t.shrinkBuf=function(e,t){return e.length===t?e:e.subarray?e.subarray(0,t):(e.length=t,e)};var i={arraySet:function(e,t,r,n,i){if(t.subarray&&e.subarray)e.set(t.subarray(r,r+n),i);else for(var a=0;a<n;a++)e[i+a]=t[r+a];},flattenChunks:function(e){var t,r,n,i,a,s;for(n=0,t=0,r=e.length;t<r;t++)n+=e[t].length;for(s=new Uint8Array(n),i=0,t=0,r=e.length;t<r;t++)a=e[t],s.set(a,i),i+=a.length;return s}},a={arraySet:function(e,t,r,n,i){for(var a=0;a<n;a++)e[i+a]=t[r+a];},flattenChunks:function(e){return [].concat.apply([],e)}};t.setTyped=function(e){e?(t.Buf8=Uint8Array,t.Buf16=Uint16Array,t.Buf32=Int32Array,t.assign(t,i)):(t.Buf8=Array,t.Buf16=Array,t.Buf32=Array,t.assign(t,a));},t.setTyped(r);},9846:()=>{}},t={},r=function r(n){var i=t[n];if(void 0!==i)return i.exports;var a=t[n]={exports:{}};return e[n].call(a.exports,a,a.exports,r),a.exports}(5159);return r})();
 
    class FileHandler {
 
@@ -42697,6 +42831,49 @@
            const end = Number.parseInt(se[1].replace(/,/g, ""));
            return new Locus({chr, start, end})
        }
+
+       /**
+        * Return true if the locus string represents a single base, e.g. "chr1:12345" or "chr1:12345-12345"
+        * @param locus
+        * @returns {boolean}
+        */
+       static isSingleBaseLocusString(locus) {
+
+           if (!locus || typeof locus !== 'string') {
+               return false
+           }
+
+           const parts = locus.split(':');
+           if (parts.length <= 1) {
+               return false
+           }
+
+           const range = parts[1].replace(/,/g, '');
+           if (!range) {
+               return false
+           }
+
+           const rangeParts = range.split('-');
+           const startString = rangeParts[0];
+           const start = parseInt(startString, 10);
+
+           if (String(start) !== startString || !Number.isInteger(start)) {
+               return false
+           }
+
+           if (rangeParts.length === 1) {
+               return true
+           }
+
+           const endString = rangeParts[1];
+           const end = parseInt(endString, 10);
+
+           if (String(end) !== endString || !Number.isInteger(end)) {
+               return false
+           }
+
+           return start === end
+       }
    }
 
    /*!
@@ -46152,18 +46329,17 @@
                        }
                    }
                }
-           }
 
-           // If we get here check downsampled intervals
-           if (offsetY < minGroupY && features.downsampledIntervals) {
-               for (const interval of features.downsampledIntervals) {
-                   if (interval.start <= genomicLocation && interval.end >= genomicLocation) {
-                       return interval
+               // If we get here check downsampled intervals
+               if (offsetY < minGroupY && features.downsampledIntervals) {
+                   for (const interval of features.downsampledIntervals) {
+                       if (interval.start <= genomicLocation && interval.end >= genomicLocation) {
+                           return interval
+                       }
                    }
                }
            }
 
-
        }
 
        /**
@@ -46828,7 +47004,7 @@
 
            IGVGraphics.fillRect(options.context, 0, options.pixelTop, options.pixelWidth, options.pixelHeight, {'fillStyle': "rgb(255, 255, 255)"});
 
-           if (true === this.showCoverage && this.coverageTrackHeight > 0) {
+           if (true === this.showCoverage && this.coverageTrackHeight > 0 && false !== this.config.showAxis) {
                this.trackView.axisCanvas.style.display = 'block';
                this.coverageTrack.draw(options);
            } else {
@@ -66815,33 +66991,45 @@ ${indent}columns: ${matrix.columns}
 
        return loci.map(l => {
 
-           const locus = Object.assign({}, l);  // Copy as we might mutate this object
+           let referenceFrame;
+           if (l.bpPerPixel) {
+               // This is an explicit locus with bpPerPixel defined, just use it.
+               referenceFrame = new ReferenceFrame(
+                   genome,
+                   l.chr,
+                   l.start,
+                   l.start + viewportWidth * l.bpPerPixel,
+                   l.bpPerPixel
+               );
+           } else {
+               const locus = Object.assign({}, l);  // Copy as we might mutate this object
 
-           // If a flanking region is defined, and the search object is a feature (has a name) type, adjust start and end
-           if (browserFlanking && locus.name) {
-               locus.start = Math.max(0, locus.start - browserFlanking);
-               locus.end += browserFlanking;
-           }
+               // If a flanking region is defined, and the search object is a feature (has a name) type, adjust start and end
+               if (browserFlanking && locus.name) {
+                   locus.start = Math.max(0, locus.start - browserFlanking);
+                   locus.end += browserFlanking;
+               }
 
-           // Validate the range.  This potentionally modifies start & end of locus.
-           if (!isSoftclipped) {
-               const chromosome = genome.getChromosome(locus.chr);
-               validateGenomicExtent(chromosome.bpLength, locus, minimumBases);
-           }
+               // Validate the range.  This potentionally modifies start & end of locus.
+               if (!isSoftclipped) {
+                   const chromosome = genome.getChromosome(locus.chr);
+                   validateGenomicExtent(chromosome.bpLength, locus, minimumBases);
+               }
 
-           const referenceFrame = new ReferenceFrame(
-               genome,
-               locus.chr,
-               locus.start,
-               locus.end,
-               (locus.end - locus.start) / viewportWidth
-           );
+               referenceFrame = new ReferenceFrame(
+                   genome,
+                   locus.chr,
+                   locus.start,
+                   locus.end,
+                   (locus.end - locus.start) / viewportWidth
+               );
+           }
 
            return referenceFrame
        })
    }
 
-   const _version = "3.5.0";
+   const _version = "3.5.2";
    function version() {
        return _version
    }
@@ -73110,7 +73298,7 @@ ${indent}columns: ${matrix.columns}
        }
    }
 
-   var igvCss = '.igv-ui-dropdown{cursor:default;position:absolute;top:0;left:0;z-index:2048;border-color:#7f7f7f;border-style:solid;border-width:1px;font-family:\"Open Sans\",sans-serif;font-size:small;font-weight:400;background-color:#fff}.igv-ui-dropdown>div{overflow-y:auto;overflow-x:hidden;background-color:#fff}.igv-ui-dropdown>div>div{padding:4px;width:100%;overflow-x:hidden;text-overflow:ellipsis;white-space:nowrap;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:1px;background-color:#fff}.igv-ui-dropdown>div>div:last-child{border-bottom-color:rgba(0,0,0,0);border-bottom-width:0}.igv-ui-dropdown>div>div:hover{cursor:pointer;background-color:rgba(0,0,0,.04)}.igv-ui-popover{cursor:default;position:absolute;z-index:2048;border-color:#7f7f7f;border-radius:5px;border-style:solid;border-width:1px;font-family:\"Open Sans\",sans-serif;font-size:small;background-color:#fff}.igv-ui-popover>div:first-child{display:flex;flex-direction:row;flex-wrap:nowrap;justify-content:space-between;align-items:center;width:100%;height:24px;cursor:move;border-top-width:0;border-top-left-radius:5px;border-top-right-radius:5px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee}.igv-ui-popover>div:first-child>div:first-child{margin-left:4px}.igv-ui-popover>div:first-child>div:last-child{margin-right:4px;height:12px;width:12px;color:#7f7f7f}.igv-ui-popover>div:first-child>div:last-child:hover{cursor:pointer;color:#444}.igv-ui-popover>div:last-child{user-select:text;overflow-y:auto;overflow-x:hidden;max-height:400px;max-width:800px;background-color:#fff;border-bottom-width:0;border-bottom-left-radius:5px;border-bottom-right-radius:5px}.igv-ui-popover>div:last-child>div{margin-left:4px;margin-right:4px;min-width:220px;overflow-x:hidden;text-overflow:ellipsis;white-space:nowrap}.igv-ui-popover>div:last-child>div>span{font-weight:bolder}.igv-ui-popover>div:last-child hr{width:100%}.igv-track-label-popover{position:absolute;z-index:2048;border:1px solid #7f7f7f;border-radius:5px;background:#fff;font-family:\"Open Sans\",sans-serif;font-size:small;min-width:260px;max-width:800px;box-shadow:0 2px 8px rgba(0,0,0,.12);user-select:text}.igv-track-label-popover__header{display:flex;align-items:center;justify-content:space-between;height:24px;background:#eee;border-top-left-radius:5px;border-top-right-radius:5px;border-bottom:1px solid #7f7f7f;padding:0 8px;cursor:move}.igv-track-label-popover__title{font-weight:bold;font-size:1em;white-space:nowrap;overflow:hidden;text-overflow:ellipsis}.igv-track-label-popover__close{width:14px;height:14px;color:#7f7f7f;display:flex;align-items:center;justify-content:center;border-radius:2px;cursor:pointer;transition:background .2s,color .2s;margin-left:8px}.igv-track-label-popover__close svg{width:14px;height:14px}.igv-track-label-popover__close:hover,.igv-track-label-popover__close:focus{background:#ddd;color:#444;outline:none}.igv-track-label-popover__body{max-height:400px;overflow-y:auto;padding:8px 0;background:#fff;border-bottom-left-radius:5px;border-bottom-right-radius:5px}.igv-track-label-popover__row{display:flex;align-items:baseline;margin:0 12px 4px 12px;min-width:220px;white-space:nowrap;overflow-x:hidden;text-overflow:ellipsis}.igv-track-label-popover__key{font-weight:bold;margin-right:.5em}.igv-track-label-popover__value{font-weight:normal;flex:1 1 auto;overflow-x:hidden;text-overflow:ellipsis}.igv-track-label-popover hr{width:100%;border:none;border-top:1px solid #7f7f7f;margin:8px 0}.igv-ui-alert-dialog-container{position:fixed;top:20%;left:50%;transform:translateX(-50%);z-index:2048;box-sizing:content-box;width:400px;height:200px;border-color:#7f7f7f;border-radius:5px;border-style:solid;border-width:thin;outline:none;font-family:\"Open Sans\",sans-serif;font-size:15px;font-weight:400;background-color:#fff;display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:space-between;align-items:center}.igv-ui-alert-dialog-container>div:first-child{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center;width:100%;height:24px;cursor:move;border-top-left-radius:5px;border-top-right-radius:5px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee}.igv-ui-alert-dialog-container>div:first-child div:first-child{padding-left:8px}.igv-ui-alert-dialog-container .igv-ui-alert-dialog-body{-webkit-user-select:text;-moz-user-select:text;-ms-user-select:text;user-select:text;color:#373737;width:100%;height:calc(100% - 24px - 64px);overflow-y:scroll}.igv-ui-alert-dialog-container .igv-ui-alert-dialog-body .igv-ui-alert-dialog-body-copy{margin:16px;width:auto;height:auto;overflow-wrap:break-word;word-break:break-word;background-color:#fff;border:unset}.igv-ui-alert-dialog-container>div:last-child{width:100%;margin-bottom:10px;background-color:#fff;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:center;align-items:center}.igv-ui-alert-dialog-container>div:last-child div{margin:unset;width:40px;height:30px;line-height:30px;text-align:center;color:#fff;font-family:\"Open Sans\",sans-serif;font-size:small;font-weight:400;border-color:#2b81af;border-style:solid;border-width:thin;border-radius:4px;background-color:#2b81af}.igv-ui-alert-dialog-container>div:last-child div:hover{cursor:pointer;border-color:#25597f;background-color:#25597f}.igv-ui-generic-dialog-container{box-sizing:content-box;position:fixed;top:20%;left:75%;transform:translateX(-50%);z-index:2048;background-color:#fff;cursor:pointer;width:300px;height:fit-content;padding-bottom:16px;border-color:#7f7f7f;border-radius:5px;border-style:solid;border-width:thin;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-header{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center;width:100%;height:24px;cursor:move;border-top-left-radius:5px;border-top-right-radius:5px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-header div{margin-right:4px;margin-bottom:2px;height:12px;width:12px;color:#7f7f7f}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-header div:hover{cursor:pointer;color:#444}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-one-liner{color:#373737;width:95%;line-height:24px;text-align:left;margin-top:8px;padding-left:8px;overflow-wrap:break-word;background-color:#fff}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-label-input{margin-top:8px;width:95%;height:24px;color:#373737;line-height:24px;padding-left:8px;background-color:#fff;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-label-input>div{width:fit-content;height:100%;font-size:16px;text-align:right;padding-right:8px;background-color:#fff}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-label-input input{display:block;height:100%;width:100%;padding-left:4px;font-family:\"Open Sans\",sans-serif;font-weight:400;color:#373737;text-align:left;outline:none;border-style:solid;border-width:thin;border-color:#7f7f7f;background-color:#fff}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-label-input input{width:50%;font-size:16px}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-input{margin-top:8px;width:calc(100% - 16px);height:24px;color:#373737;line-height:24px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-input input{display:block;height:100%;width:100%;padding-left:4px;font-family:\"Open Sans\",sans-serif;font-weight:400;color:#373737;text-align:left;outline:none;border-style:solid;border-width:thin;border-color:#7f7f7f;background-color:#fff}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-input input{font-size:16px}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-input input[type=range]{width:70%;-webkit-appearance:none;background:linear-gradient(90deg, white, black);outline:none;margin:0}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-input output{display:block;height:100%;width:20%;font-size:16px}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-ok-cancel{width:100%;height:28px;padding-top:16px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-ok-cancel>div{color:#fff;font-family:\"Open Sans\",sans-serif;font-size:14px;font-weight:400;width:75px;height:28px;line-height:28px;text-align:center;border-color:rgba(0,0,0,0);border-style:solid;border-width:thin;border-radius:2px}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-ok-cancel>div:first-child{margin-left:32px;margin-right:0;background-color:#5ea4e0}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-ok-cancel>div:last-child{margin-left:0;margin-right:32px;background-color:#c4c4c4}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-ok-cancel>div:first-child:hover{cursor:pointer;background-color:#3b5c7f}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-ok-cancel>div:last-child:hover{cursor:pointer;background-color:#7f7f7f}.igv-ui-generic-container{position:fixed;cursor:pointer;background-color:#fff;z-index:2048;box-sizing:content-box;width:300px;height:200px;top:20%;left:75%;transform:translateX(-50%);display:flex;flex-direction:row;flex-wrap:wrap;justify-content:flex-start;align-items:center}.igv-ui-generic-container>div:nth-child(1){cursor:move;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center;height:24px;width:100%;background-color:#ddd}.igv-ui-generic-container>div:nth-child(1)>div{display:block;color:#5f5f5f;cursor:pointer;width:14px;height:14px;margin-right:8px;margin-bottom:4px}.igv-ui-colorpicker-container{background-color:#eee;height:fit-content;flex-direction:column;flex-wrap:nowrap}.igv-ui-colorpicker-container>div:nth-child(2){display:flex;flex-direction:row;flex-wrap:wrap;justify-content:flex-start;align-items:center}.igv-ui-colorpicker-container>div:nth-child(3){box-sizing:border-box;position:relative;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center;padding:.5rem;font-family:\"Open Sans\",sans-serif;font-size:1rem;font-weight:400;width:100%;border-top-style:solid;border-top-width:thin;border-top-color:#373737}.igv-ui-colorpicker-container>div:nth-child(4){width:100%;display:flex;flex-direction:row;flex-wrap:wrap;justify-content:flex-start;align-items:center}.igv-ui-color-swatch{position:relative;box-sizing:content-box;display:flex;flex-flow:row;flex-wrap:wrap;justify-content:center;align-items:center;margin:2px;width:32px;height:32px;border-style:solid;border-width:0;border-color:#fff;border-radius:3px}.igv-ui-color-swatch-shim{cursor:pointer;position:relative;box-sizing:content-box;display:flex;flex-flow:row;flex-wrap:wrap;justify-content:center;align-items:center;width:32px;height:32px;background-color:#fff;border-style:solid;border-width:thin;border-color:#fff;border-radius:4px}.igv-ui-dialog{z-index:2048;position:fixed;width:fit-content;height:fit-content;display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:flex-start;background-color:#fff;border-color:#7f7f7f;border-radius:5px;border-style:solid;border-width:thin;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400}.igv-ui-dialog .igv-ui-dialog-header{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center;width:100%;height:24px;cursor:move;border-top-left-radius:5px;border-top-right-radius:5px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee}.igv-ui-dialog .igv-ui-dialog-header div{margin-right:4px;margin-bottom:2px;height:12px;width:12px;color:#7f7f7f}.igv-ui-dialog .igv-ui-dialog-header div:hover{cursor:pointer;color:#444}.igv-ui-dialog .igv-ui-dialog-one-liner{width:95%;height:24px;line-height:24px;text-align:left;margin:8px;overflow-wrap:break-word;background-color:#fff;font-weight:bold}.igv-ui-dialog .igv-ui-dialog-ok-cancel{width:100%;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-ui-dialog .igv-ui-dialog-ok-cancel div{margin:16px;margin-top:32px;color:#fff;font-family:\"Open Sans\",sans-serif;font-size:14px;font-weight:400;width:75px;height:28px;line-height:28px;text-align:center;border-color:rgba(0,0,0,0);border-style:solid;border-width:thin;border-radius:2px}.igv-ui-dialog .igv-ui-dialog-ok-cancel div:first-child{background-color:#5ea4e0}.igv-ui-dialog .igv-ui-dialog-ok-cancel div:last-child{background-color:#c4c4c4}.igv-ui-dialog .igv-ui-dialog-ok-cancel div:first-child:hover{cursor:pointer;background-color:#3b5c7f}.igv-ui-dialog .igv-ui-dialog-ok-cancel div:last-child:hover{cursor:pointer;background-color:#7f7f7f}.igv-ui-dialog .igv-ui-dialog-ok{width:100%;height:36px;margin-top:32px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-ui-dialog .igv-ui-dialog-ok div{width:98px;height:36px;line-height:36px;text-align:center;color:#fff;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;border-color:#fff;border-style:solid;border-width:thin;border-radius:4px;background-color:#2b81af}.igv-ui-dialog .igv-ui-dialog-ok div:hover{cursor:pointer;background-color:#25597f}.igv-ui-panel,.igv-ui-panel-row,.igv-ui-panel-column{z-index:2048;background-color:#fff;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;display:flex;justify-content:flex-start;align-items:flex-start}.igv-ui-panel-column{display:flex;flex-direction:column}.igv-ui-panel-row{display:flex;flex-direction:row}.igv-ui-textbox{background-color:#fff;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;display:flex;justify-content:flex-start;align-items:flex-start}.igv-ui-table{background-color:#fff}.igv-ui-table thead{position:sticky;top:0}.igv-ui-table th{text-align:left}.igv-ui-table td{padding-right:20px}.igv-ui-table tr:hover{background-color:#add8e6}.igv-roi-seg-filter-dialog{box-sizing:content-box;position:fixed;top:20%;left:75%;transform:translateX(-50%);z-index:2048;background-color:#fff;cursor:pointer;width:350px;height:fit-content;padding-bottom:16px;border-color:#7f7f7f;border-radius:5px;border-style:solid;border-width:thin;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-roi-seg-filter-dialog__header{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center;width:100%;height:24px;cursor:move;border-top-left-radius:5px;border-top-right-radius:5px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee}.igv-roi-seg-filter-dialog__header div{margin-right:4px;margin-bottom:2px;height:12px;width:12px;color:#7f7f7f}.igv-roi-seg-filter-dialog__header div:hover{cursor:pointer;color:#444}.igv-roi-seg-filter-dialog__radio-group{margin-top:8px;display:flex;flex-direction:column;justify-content:flex-start;align-items:flex-start}.igv-roi-seg-filter-dialog__radio-group label{display:flex;align-items:center;gap:4px;cursor:pointer}.igv-roi-seg-filter-dialog__radio-group input[type=radio]{cursor:pointer}.igv-roi-seg-filter-dialog__radio-group .op{display:flex;flex-direction:row;justify-content:flex-start;align-items:center;margin-left:16px;margin-bottom:8px;gap:2px}.igv-roi-seg-filter-dialog__radio-group .op input[type=radio]{display:block;margin:0}.igv-roi-seg-filter-dialog__radio-group .op label{display:block;margin-left:4px}.igv-roi-seg-filter-dialog__one-liner{color:#373737;width:95%;line-height:24px;text-align:left;margin-top:8px;padding-left:8px;overflow-wrap:break-word;background-color:#fff}.igv-roi-seg-filter-dialog__input{margin-top:8px;width:80%;height:24px;color:#373737;line-height:24px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-roi-seg-filter-dialog__input input{display:block;height:100%;width:100%;padding-left:4px;font-family:\"Open Sans\",sans-serif;font-weight:400;color:#373737;text-align:left;outline:none;border-style:solid;border-width:thin;border-color:#7f7f7f;background-color:#fff}.igv-roi-seg-filter-dialog__input input{font-size:16px}.igv-roi-seg-filter-dialog__ok-cancel{width:100%;height:28px;padding-top:16px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-roi-seg-filter-dialog__ok-cancel>div{color:#fff;font-family:\"Open Sans\",sans-serif;font-size:14px;font-weight:400;width:75px;height:28px;line-height:28px;text-align:center;border-color:rgba(0,0,0,0);border-style:solid;border-width:thin;border-radius:2px}.igv-roi-seg-filter-dialog__ok-cancel>div:first-child{margin-left:32px;margin-right:0;background-color:#5ea4e0}.igv-roi-seg-filter-dialog__ok-cancel>div:last-child{margin-left:0;margin-right:32px;background-color:#c4c4c4}.igv-roi-seg-filter-dialog__ok-cancel>div:first-child:hover{cursor:pointer;background-color:#3b5c7f}.igv-roi-seg-filter-dialog__ok-cancel>div:first-child.disabled{cursor:not-allowed;background-color:#ccc;opacity:.6}.igv-roi-seg-filter-dialog__ok-cancel>div:first-child.disabled:hover{cursor:not-allowed;background-color:#ccc}.igv-roi-seg-filter-dialog__ok-cancel>div:last-child:hover{cursor:pointer;background-color:#7f7f7f}.igv-clear-filters__container{font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;display:flex;flex-direction:column;max-width:300px;background-color:#fff;padding:12px;gap:8px;border-color:#7f7f7f;border-radius:5px;border-style:solid;border-width:thin}.igv-clear-filters__row{display:flex;align-items:flex-start;padding:12px;gap:12px;cursor:pointer}.igv-clear-filters__row:last-of-type{border-bottom:none}.igv-clear-filters__track-container{border-bottom:1px solid #7f7f7f;padding-bottom:8px;margin-bottom:8px}.igv-clear-filters__track-container:last-of-type{border-bottom:none;margin-bottom:0}.igv-clear-filters__track-header{display:flex;align-items:center;padding:8px 12px;gap:12px;background-color:#f5f5f5;border-radius:4px;margin-bottom:4px;font-weight:500;font-size:14px}.igv-clear-filters__track-name{color:#333;font-weight:600}.igv-clear-filters__filter-checkbox{flex:0 0 16px;width:16px;height:16px;margin-top:2px;cursor:pointer}.igv-clear-filters__checkbox{flex:0 0 16px;width:16px;height:16px;margin-top:2px;cursor:pointer}.igv-clear-filters__content{display:flex;flex-direction:row;flex:1;gap:4px}.igv-clear-filters__description{color:#333;font-size:14px;line-height:1.4}.igv-clear-filters__region{color:#666;font-family:monospace;font-size:12px;line-height:1.4}.igv-clear-filters__button-container{display:flex;gap:8px;margin-top:8px}.igv-clear-filters__button{display:flex;align-items:center;justify-content:center;flex:1;padding:10px;background-color:#5ea4e0;color:#fff;border-color:rgba(0,0,0,0);border-style:solid;border-width:thin;border-radius:2px;cursor:pointer;font-size:14px;font-weight:400;transition:background-color .2s ease}.igv-clear-filters__button:hover{background-color:#3b5c7f}.igv-clear-filters__button--cancel{background-color:#c4c4c4}.igv-clear-filters__button--cancel:hover{background-color:#7f7f7f}.igv-navbar{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-between;align-items:center;box-sizing:border-box;width:100%;color:#444;font-size:12px;font-family:\"Open Sans\",sans-serif;font-weight:400;line-height:32px;padding-left:8px;padding-right:8px;margin-top:2px;margin-bottom:6px;height:32px;border-style:solid;border-radius:3px;border-width:thin;border-color:#bfbfbf;background-color:#f3f3f3}.igv-navbar .igv-navbar-left-container{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-between;align-items:center;height:32px;line-height:32px}.igv-navbar .igv-navbar-left-container .igv-logo{width:34px;height:32px;margin-right:8px}.igv-navbar .igv-navbar-left-container .igv-current-genome{height:32px;margin-left:4px;margin-right:4px;user-select:none;line-height:32px;vertical-align:middle;text-align:center}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-between;align-items:center;height:100%}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location .igv-chromosome-select-widget-container{display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:space-around;align-items:center;height:100%;width:125px;margin-right:4px}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location .igv-chromosome-select-widget-container select{display:block;cursor:pointer;width:100px;height:75%;outline:none;font-size:12px;font-family:\"Open Sans\",sans-serif;font-weight:400}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location .igv-locus-size-group{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-between;align-items:center;margin-left:8px;height:22px}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location .igv-locus-size-group .igv-search-container{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center;width:240px;height:22px;line-height:22px}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location .igv-locus-size-group .igv-search-container input.igv-search-input{cursor:text;width:85%;height:22px;line-height:22px;font-size:12px;font-family:\"Open Sans\",sans-serif;font-weight:400;text-align:left;padding-left:8px;margin-right:8px;outline:none;border-style:solid;border-radius:3px;border-width:thin;border-color:#bfbfbf;background-color:#fff}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location .igv-locus-size-group .igv-search-container .igv-search-icon-container{cursor:pointer;height:16px;width:16px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:center;align-items:center}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location .igv-locus-size-group .igv-windowsize-panel-container{margin-left:4px;user-select:none}.igv-navbar .igv-navbar-right-container{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-between;align-items:center}.igv-navbar .igv-navbar-right-container .igv-navbar-toggle-button-container{position:relative;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center}.igv-navbar .igv-navbar-right-container .igv-navbar-toggle-button-container-hidden{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center;height:100%}.igv-navbar .igv-navbar-right-container .igv-zoom-widget{color:#737373;font-size:18px;margin-left:8px;user-select:none;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center}.igv-navbar .igv-navbar-right-container .igv-zoom-widget div{cursor:pointer;margin-left:unset;margin-right:unset}.igv-navbar .igv-navbar-right-container .igv-zoom-widget div:first-child{height:20px;width:20px;margin-left:unset;margin-right:4px}.igv-navbar .igv-navbar-right-container .igv-zoom-widget div:last-child{height:20px;width:20px;margin-left:4px;margin-right:unset}.igv-navbar .igv-navbar-right-container .igv-zoom-widget div:nth-child(even){display:block;height:fit-content}.igv-navbar .igv-navbar-right-container .igv-zoom-widget input{display:block;width:125px}.igv-navbar .igv-navbar-right-container .igv-zoom-widget svg{display:block}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-900{color:#737373;font-size:18px;height:32px;line-height:32px;margin-left:8px;user-select:none;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-900 div{cursor:pointer;margin-left:unset;margin-right:unset}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-900 div:first-child{height:20px;width:20px;margin-left:unset;margin-right:4px}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-900 div:last-child{height:20px;width:20px;margin-left:4px;margin-right:unset}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-900 div:nth-child(even){width:0;height:0;display:none}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-900 input{width:0;height:0;display:none}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-900 svg{display:block}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-hidden{display:none}.igv-navbar-button{display:block;box-sizing:unset;padding-left:6px;padding-right:6px;height:18px;text-transform:capitalize;user-select:none;line-height:18px;text-align:center;vertical-align:middle;font-family:\"Open Sans\",sans-serif;font-size:11px;font-weight:200;color:#737373;background-color:#f3f3f3;border-color:#737373;border-style:solid;border-width:thin;border-radius:6px}.igv-navbar-button:hover{cursor:pointer}.igv-navbar-button-clicked{color:#fff;background-color:#737373}.igv-navbar-icon-button{cursor:pointer;position:relative;width:24px;height:24px;margin-left:4px;margin-right:4px;border:none;background-size:contain;background-repeat:no-repeat;background-position:center}.igv-navbar-icon-button>div:first-child{z-index:512;position:absolute;top:36px;left:-18px;width:24px;height:24px;border:none;background-size:contain;background-repeat:no-repeat;background-position:center}.igv-navbar-icon-button>div:last-child{z-index:512;position:absolute;top:36px;left:18px;width:24px;height:24px;border:none;background-size:contain;background-repeat:no-repeat;background-position:center}.igv-navbar-text-button{cursor:pointer;position:relative;margin-left:2px;margin-right:2px;border:none;display:flex;justify-content:center;align-items:center}.igv-navbar-text-button>div:nth-child(2){z-index:512;position:absolute;top:36px;left:0;width:38px;height:18px;border:none;background-size:contain;background-repeat:no-repeat;background-position:center}.igv-navbar-text-button>div:nth-child(3){z-index:512;position:absolute;top:36px;left:42px;width:38px;height:18px;border:none;background-size:contain;background-repeat:no-repeat;background-position:center}#igv-text-button-label{text-anchor:middle;dominant-baseline:middle}.igv-navbar-text-button-svg-inactive rect{stroke:#737373;fill:#fff}.igv-navbar-text-button-svg-inactive text{fill:#737373}.igv-navbar-text-button-svg-inactive tspan{dominant-baseline:middle}.igv-navbar-text-button-svg-hover rect{stroke:#737373;fill:#737373}.igv-navbar-text-button-svg-hover text{fill:#fff}.igv-navbar-text-button-svg-hover tspan{dominant-baseline:middle}#igv-save-svg-group rect{stroke:#737373;fill:#fff}#igv-save-svg-group text{fill:#737373}#igv-save-svg-group:hover rect{stroke:#737373;fill:#737373}#igv-save-svg-group:hover text{fill:#fff}#igv-save-png-group rect{stroke:#737373;fill:#fff}#igv-save-png-group text{fill:#737373}#igv-save-png-group:hover rect{stroke:#737373;fill:#737373}#igv-save-png-group:hover text{fill:#fff}.igv-zoom-in-notice-container{z-index:256;position:absolute;top:8px;left:50%;transform:translate(-50%, 0%);display:flex;flex-direction:row;flex-wrap:nowrap;justify-content:center;align-items:center;background-color:#fff}.igv-zoom-in-notice-container>div{padding-left:4px;padding-right:4px;padding-top:2px;padding-bottom:2px;width:100%;height:100%;font-family:\"Open Sans\",sans-serif;font-size:14px;font-weight:400;color:#3f3f3f}.igv-zoom-in-notice{position:absolute;top:10px;left:50%}.igv-zoom-in-notice div{position:relative;left:-50%;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;color:#3f3f3f;background-color:hsla(0,0%,100%,.51);z-index:64}.igv-container-spinner{position:absolute;top:90%;left:50%;transform:translate(-50%, -50%);z-index:1024;width:24px;height:24px;pointer-events:none;color:#737373}.igv-multi-locus-close-button{position:absolute;top:2px;right:0;padding-left:2px;padding-right:2px;width:12px;height:12px;color:#666;background-color:#fff;z-index:1000}.igv-multi-locus-close-button>svg{vertical-align:top}.igv-multi-locus-close-button:hover{cursor:pointer;color:#434343}.igv-multi-locus-ruler-label{z-index:64;position:absolute;top:2px;left:0;width:100%;height:12px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:center;align-items:center}.igv-multi-locus-ruler-label>div{font-family:\"Open Sans\",sans-serif;font-size:12px;color:#101010;background-color:#fff}.igv-multi-locus-ruler-label>div{cursor:pointer}.igv-multi-locus-ruler-label-square-dot{z-index:64;position:absolute;left:50%;top:5%;transform:translate(-50%, 0%);background-color:#fff;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-multi-locus-ruler-label-square-dot>div:first-child{width:14px;height:14px}.igv-multi-locus-ruler-label-square-dot>div:last-child{margin-left:16px;font-family:\"Open Sans\",sans-serif;font-size:14px;font-weight:400;color:#101010}.igv-ruler-sweeper{display:none;pointer-events:none;position:absolute;top:26px;bottom:0;left:0;width:0;z-index:99999;background-color:rgba(68,134,247,.25)}.igv-ruler-tooltip{pointer-events:none;z-index:128;position:absolute;top:0;left:0;width:1px;height:32px;background-color:rgba(0,0,0,0);display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-ruler-tooltip>div{pointer-events:none;width:128px;height:auto;padding:1px;color:#373737;font-size:10px;font-family:\"Open Sans\",sans-serif;font-weight:400;background-color:#fff;border-style:solid;border-width:thin;border-color:#373737}.igv-track-label{position:absolute;left:8px;top:8px;width:auto;height:auto;max-width:50%;padding-left:4px;padding-right:4px;white-space:nowrap;overflow:hidden;text-overflow:ellipsis;font-family:\"Open Sans\",sans-serif;font-size:small;font-weight:400;text-align:center;user-select:none;-moz-user-select:none;-webkit-user-select:none;border-color:#444;border-radius:2px;border-style:solid;border-width:thin;background-color:#fff;z-index:128;cursor:pointer}.igv-track-label:hover,.igv-track-label:focus,.igv-track-label:active{background-color:#e8e8e8}.igv-track-label-popup-shim{position:absolute;right:8px;top:8px;width:auto;height:auto;max-width:50%;padding-left:4px;padding-right:4px;white-space:nowrap;overflow:hidden;text-overflow:ellipsis;font-family:\"Open Sans\",sans-serif;font-size:small;font-weight:400;text-align:center;user-select:none;-moz-user-select:none;-webkit-user-select:none;border-color:#444;border-radius:2px;border-style:solid;border-width:thin;background-color:#fff;z-index:128}.igv-attribute-group-label{position:absolute;right:5px;z-index:128;width:auto;height:auto;max-width:50%;padding-left:4px;padding-right:4px;white-space:nowrap;overflow:hidden;text-overflow:ellipsis;font-family:\"Open Sans\",sans-serif;font-size:small;font-weight:400;text-align:center;user-select:none;-moz-user-select:none;-webkit-user-select:none;border-color:#444;border-radius:2px;border-style:solid;border-width:thin;background-color:#fff}.igv-attribute-group-line{position:absolute;left:0px;width:100%;height:1px;background-color:rgba(0,0,0,0);border-top:1px dotted #666;pointer-events:none;z-index:127}.igv-center-line{display:none;pointer-events:none;position:absolute;top:0;bottom:0;left:50%;transform:translateX(-50%);z-index:8;user-select:none;-moz-user-select:none;-webkit-user-select:none;border-left-style:dashed;border-left-width:thin;border-right-style:dashed;border-right-width:thin}.igv-center-line-wide{background-color:rgba(0,0,0,0);border-left-color:rgba(127,127,127,.51);border-right-color:rgba(127,127,127,.51)}.igv-center-line-thin{background-color:rgba(0,0,0,0);border-left-color:rgba(127,127,127,.51);border-right-color:rgba(0,0,0,0)}.igv-cursor-guide-horizontal{display:none;pointer-events:none;user-select:none;-moz-user-select:none;-webkit-user-select:none;position:absolute;left:0;right:0;top:50%;height:1px;z-index:32;margin-left:50px;margin-right:54px;border-top-style:dotted;border-top-width:thin;border-top-color:rgba(127,127,127,.76)}.igv-cursor-guide-vertical{pointer-events:none;user-select:none;-moz-user-select:none;-webkit-user-select:none;position:absolute;top:0;bottom:0;left:50%;width:1px;z-index:32;border-left-style:dotted;border-left-width:thin;border-left-color:rgba(127,127,127,.76);display:none}.igv-user-feedback{position:fixed;top:50%;left:50%;transform:translate(-50%, -50%);width:512px;height:360px;z-index:2048;background-color:#fff;border-color:#a2a2a2;border-style:solid;border-width:thin;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;color:#444;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-user-feedback div:first-child{position:relative;height:24px;width:100%;background-color:#fff;border-bottom-color:#a2a2a2;border-bottom-style:solid;border-bottom-width:thin}.igv-user-feedback div:first-child div{position:absolute;top:2px;width:16px;height:16px;background-color:rgba(0,0,0,0)}.igv-user-feedback div:first-child div:first-child{left:8px}.igv-user-feedback div:first-child div:last-child{cursor:pointer;right:8px}.igv-user-feedback div:last-child{width:100%;height:calc(100% - 24px);border-width:0}.igv-user-feedback div:last-child div{width:auto;height:auto;margin:8px}.igv-generic-dialog-container{position:fixed;top:20%;left:75%;transform:translateX(-50%);width:300px;height:200px;border-color:#7f7f7f;border-radius:4px;border-style:solid;border-width:thin;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;z-index:2048;background-color:#fff;display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-generic-dialog-container .igv-generic-dialog-header{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center;width:100%;height:24px;cursor:move;border-top-left-radius:4px;border-top-right-radius:4px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee}.igv-generic-dialog-container .igv-generic-dialog-header div{margin-right:4px;margin-bottom:2px;height:12px;width:12px;color:#7f7f7f}.igv-generic-dialog-container .igv-generic-dialog-header div:hover{cursor:pointer;color:#444}.igv-generic-dialog-container .igv-generic-dialog-one-liner{color:#373737;width:95%;height:24px;line-height:24px;text-align:left;margin-top:8px;padding-left:8px;overflow-wrap:break-word;background-color:#fff}.igv-generic-dialog-container .igv-generic-dialog-label-input{margin-top:8px;width:95%;height:24px;color:#373737;line-height:24px;padding-left:8px;background-color:#fff;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-generic-dialog-container .igv-generic-dialog-label-input div{width:30%;height:100%;font-size:16px;text-align:right;padding-right:8px;background-color:#fff}.igv-generic-dialog-container .igv-generic-dialog-label-input input{display:block;height:100%;width:100%;padding-left:4px;font-family:\"Open Sans\",sans-serif;font-weight:400;color:#373737;text-align:left;outline:none;border-style:solid;border-width:thin;border-color:#7f7f7f;background-color:#fff}.igv-generic-dialog-container .igv-generic-dialog-label-input input{width:50%;font-size:16px}.igv-generic-dialog-container .igv-generic-dialog-input{margin-top:8px;width:calc(100% - 16px);height:24px;color:#373737;line-height:24px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-generic-dialog-container .igv-generic-dialog-input input{display:block;height:100%;width:100%;padding-left:4px;font-family:\"Open Sans\",sans-serif;font-weight:400;color:#373737;text-align:left;outline:none;border-style:solid;border-width:thin;border-color:#7f7f7f;background-color:#fff}.igv-generic-dialog-container .igv-generic-dialog-input input{font-size:16px}.igv-generic-dialog-container .igv-generic-dialog-ok-cancel{width:100%;height:28px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-generic-dialog-container .igv-generic-dialog-ok-cancel div{margin-top:32px;color:#fff;font-family:\"Open Sans\",sans-serif;font-size:14px;font-weight:400;width:75px;height:28px;line-height:28px;text-align:center;border-color:rgba(0,0,0,0);border-style:solid;border-width:thin;border-radius:2px}.igv-generic-dialog-container .igv-generic-dialog-ok-cancel div:first-child{margin-left:32px;margin-right:0;background-color:#5ea4e0}.igv-generic-dialog-container .igv-generic-dialog-ok-cancel div:last-child{margin-left:0;margin-right:32px;background-color:#c4c4c4}.igv-generic-dialog-container .igv-generic-dialog-ok-cancel div:first-child:hover{cursor:pointer;background-color:#3b5c7f}.igv-generic-dialog-container .igv-generic-dialog-ok-cancel div:last-child:hover{cursor:pointer;background-color:#7f7f7f}.igv-generic-dialog-container .igv-generic-dialog-ok{width:100%;height:36px;margin-top:32px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-generic-dialog-container .igv-generic-dialog-ok div{width:98px;height:36px;line-height:36px;text-align:center;color:#fff;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;border-color:#fff;border-style:solid;border-width:thin;border-radius:4px;background-color:#2b81af}.igv-generic-dialog-container .igv-generic-dialog-ok div:hover{cursor:pointer;background-color:#25597f}.igv-generic-container{position:fixed;top:20%;left:75%;transform:translateX(-50%);z-index:2048;background-color:#fff;cursor:pointer;display:flex;flex-direction:row;flex-wrap:wrap;justify-content:flex-start;align-items:center}.igv-generic-container>div:nth-child(1){cursor:move;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center;height:24px;width:100%;background-color:#ddd}.igv-generic-container>div:nth-child(1) i{display:block;color:#5f5f5f;cursor:pointer;width:14px;height:14px;margin-right:8px;margin-bottom:4px}.igv-menu-popup{position:absolute;top:0;left:0;width:max-content;max-width:400px;z-index:2048;cursor:pointer;font-family:\"Open Sans\",sans-serif;font-size:small;font-weight:400;color:#4b4b4b;background:#fff;border-radius:4px;border-color:#7f7f7f;border-style:solid;border-width:thin;display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-end;text-align:left}.igv-menu-popup>div:not(:first-child){width:100%}.igv-menu-popup>div:not(:first-child)>div{background:#fff}.igv-menu-popup>div:not(:first-child)>div.context-menu{padding-left:4px;padding-right:4px}.igv-menu-popup>div:not(:first-child)>div:last-child{border-bottom-left-radius:4px;border-bottom-right-radius:4px;border-bottom-color:rgba(0,0,0,0);border-bottom-style:solid;border-bottom-width:thin}.igv-menu-popup>div:not(:first-child)>div:hover{background:#efefef}.igv-menu-popup-shim{padding-left:8px;padding-right:8px;padding-bottom:1px;padding-top:1px}.igv-menu-popup-header{position:relative;width:100%;height:24px;cursor:move;border-top-color:rgba(0,0,0,0);border-top-left-radius:4px;border-top-right-radius:4px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center}.igv-menu-popup-header div{margin-right:4px;height:12px;width:12px;color:#7f7f7f}.igv-menu-popup-header div:hover{cursor:pointer;color:#444}.igv-menu-popup-check-container{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center;width:100%;height:20px;margin-right:4px;background-color:rgba(0,0,0,0)}.igv-menu-popup-check-container div{padding-top:2px;padding-left:8px}.igv-menu-popup-check-container div:first-child{position:relative;width:12px;height:12px}.igv-menu-popup-check-container div:first-child svg{position:absolute;width:12px;height:12px}.igv-loading-spinner-container{z-index:1024;position:absolute;top:50%;left:50%;transform:translate(-50%, -50%);width:32px;height:32px;display:flex;flex-direction:row;flex-wrap:nowrap;justify-content:center;align-items:center}.igv-loading-spinner-container>div{box-sizing:border-box;width:100%;height:100%;border-radius:50%;border:4px solid rgba(128,128,128,.5);border-top-color:#fff;animation:spin 1s ease-in-out infinite;-webkit-animation:spin 1s ease-in-out infinite}@keyframes spin{to{-webkit-transform:rotate(360deg);transform:rotate(360deg)}}@-webkit-keyframes spin{to{-webkit-transform:rotate(360deg);transform:rotate(360deg)}}.igv-roi-menu{position:absolute;z-index:512;font-family:\"Open Sans\",sans-serif;font-size:small;font-weight:400;color:#4b4b4b;background-color:#fff;width:192px;border-radius:4px;border-color:#7f7f7f;border-style:solid;border-width:thin;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:stretch}.igv-roi-menu>div:first-child{height:24px;border-top-color:rgba(0,0,0,0);border-top-left-radius:4px;border-top-right-radius:4px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center}.igv-roi-menu>div:first-child>div{margin-right:4px;height:12px;width:12px;color:#7f7f7f}.igv-roi-menu>div:first-child>div:hover{cursor:pointer;color:#444}.igv-roi-menu>div:last-child{background-color:#fff;border-bottom-left-radius:4px;border-bottom-right-radius:4px;border-bottom-color:rgba(0,0,0,0);border-bottom-style:solid;border-bottom-width:0;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:stretch;text-align:start;vertical-align:middle}.igv-roi-menu>div:last-child>div{height:24px;padding-left:4px;border-bottom-style:solid;border-bottom-width:thin;border-bottom-color:#7f7f7f}.igv-roi-menu>div:last-child>div:not(:first-child):hover{cursor:pointer;background-color:rgba(127,127,127,.1)}.igv-roi-menu>div:last-child div:first-child{font-style:italic;text-align:center;padding-right:4px;white-space:nowrap;overflow:hidden;text-overflow:ellipsis}.igv-roi-menu>div:last-child>div:last-child{border-bottom-width:0;border-bottom-color:rgba(0,0,0,0)}.igv-roi-placeholder{font-style:normal;color:rgba(75,75,75,.6)}.igv-roi-table{position:absolute;z-index:1024;display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:flex-start;align-items:stretch;resize:both;overflow:hidden;width:min-content;max-width:1600px;border-color:#7f7f7f;border-radius:4px;border-style:solid;border-width:thin;font-family:\"Open Sans\",sans-serif;font-size:12px;font-weight:400;background-color:#fff;cursor:default}.igv-roi-table>div{height:24px;font-size:14px;text-align:start;vertical-align:middle;line-height:24px}.igv-roi-table>div:first-child{border-color:rgba(0,0,0,0);border-top-left-radius:4px;border-top-right-radius:4px;border-top-width:0;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee;cursor:move;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-between;align-items:center}.igv-roi-table>div:first-child>div:first-child{text-align:center;white-space:nowrap;text-overflow:ellipsis;overflow:hidden;margin-left:4px;margin-right:4px;width:calc(100% - 4px - 12px)}.igv-roi-table>div:first-child>div:last-child{margin-right:4px;margin-bottom:2px;height:12px;width:12px;color:#7f7f7f}.igv-roi-table>div:first-child>div:last-child>svg{display:block}.igv-roi-table>div:first-child>div:last-child:hover{cursor:pointer;color:#444}.igv-roi-table>.igv-roi-table-description{padding:4px;margin-left:4px;word-break:break-all;overflow-y:auto;display:flex;flex-flow:row;flex-wrap:nowrap;background-color:rgba(0,0,0,0)}.igv-roi-table>.igv-roi-table-goto-explainer{margin-top:5px;margin-left:4px;color:#7f7f7f;font-style:italic;height:24px;border-top:solid #d3d3d3;background-color:rgba(0,0,0,0)}.igv-roi-table>.igv-roi-table-column-titles{height:24px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:stretch;align-items:stretch;padding-right:16px;background-color:#fff;border-top-color:#7f7f7f;border-top-style:solid;border-top-width:thin;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin}.igv-roi-table>.igv-roi-table-column-titles>div{font-size:14px;vertical-align:middle;line-height:24px;text-align:left;margin-left:4px;height:24px;overflow:hidden;text-overflow:ellipsis;border-right-color:#7f7f7f;border-right-style:solid;border-right-width:thin}.igv-roi-table>.igv-roi-table-column-titles>div:last-child{border-right:unset}.igv-roi-table>.igv-roi-table-row-container{display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:flex-start;align-items:stretch;overflow:auto;height:360px;flex:1 1 auto;background-color:rgba(0,0,0,0)}.igv-roi-table>.igv-roi-table-row-container>.igv-roi-table-row{height:24px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:stretch;align-items:stretch}.igv-roi-table>.igv-roi-table-row-container>.igv-roi-table-row>div{font-size:14px;vertical-align:middle;line-height:24px;text-align:left;margin-left:4px;height:24px;white-space:nowrap;overflow:hidden;text-overflow:ellipsis;border-right-color:rgba(0,0,0,0);border-right-style:solid;border-right-width:thin}.igv-roi-table>.igv-roi-table-row-container>.igv-roi-table-row>div:last-child{border-right:unset}.igv-roi-table>.igv-roi-table-row-container>.igv-roi-table-row-hover{background-color:rgba(0,0,0,.04)}.igv-roi-table>div:last-child{min-height:32px;height:32px;line-height:32px;border-top-color:#7f7f7f;border-top-style:solid;border-top-width:thin;border-bottom-color:rgba(0,0,0,0);border-bottom-left-radius:4px;border-bottom-right-radius:4px;border-bottom-width:0;background-color:#eee;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-roi-table-row-selected{background-color:rgba(0,0,0,.125)}.igv-roi-table-button{cursor:pointer;height:20px;user-select:none;line-height:20px;text-align:center;vertical-align:middle;font-family:\"Open Sans\",sans-serif;font-size:13px;font-weight:400;color:#000;padding-left:6px;padding-right:6px;background-color:#efefef;border-color:#000;border-style:solid;border-width:thin;border-radius:3px}.igv-roi-table-button:hover{font-weight:400;background-color:rgba(0,0,0,.13)}.igv-roi-region{z-index:64;position:absolute;top:0;bottom:0;pointer-events:none;overflow:visible;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:stretch}.igv-roi-region>div{position:relative;width:100%;height:8px;pointer-events:auto}.igv-roi-menu-row{height:24px;padding-left:8px;font-size:small;text-align:start;vertical-align:middle;line-height:24px;background-color:#fff}.igv-roi-menu-row-edit-description{width:-webkit-fill-available;font-size:small;text-align:start;vertical-align:middle;background-color:#fff;padding-left:4px;padding-right:4px;padding-bottom:4px;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:stretch;align-items:stretch}.igv-roi-menu-row-edit-description>label{margin-left:2px;margin-bottom:0;display:block;width:-webkit-fill-available}.igv-roi-menu-row-edit-description>input{display:block;margin-left:2px;margin-right:2px;margin-bottom:1px;width:-webkit-fill-available}.picker_wrapper.no_alpha .picker_alpha{display:none}.picker_wrapper.no_editor .picker_editor{position:absolute;z-index:-1;opacity:0}.picker_wrapper.no_cancel .picker_cancel{display:none}.layout_default.picker_wrapper{display:flex;flex-flow:row wrap;justify-content:space-between;align-items:stretch;font-size:10px;width:25em;padding:.5em}.layout_default.picker_wrapper input,.layout_default.picker_wrapper button{font-size:1rem}.layout_default.picker_wrapper>*{margin:.5em}.layout_default.picker_wrapper::before{content:\"\";display:block;width:100%;height:0;order:1}.layout_default .picker_slider,.layout_default .picker_selector{padding:1em}.layout_default .picker_hue{width:100%}.layout_default .picker_sl{flex:1 1 auto}.layout_default .picker_sl::before{content:\"\";display:block;padding-bottom:100%}.layout_default .picker_editor{order:1;width:6.5rem}.layout_default .picker_editor input{width:100%;height:100%}.layout_default .picker_sample{order:1;flex:1 1 auto}.layout_default .picker_done,.layout_default .picker_cancel{order:1}.picker_wrapper{box-sizing:border-box;background:#f2f2f2;box-shadow:0 0 0 1px silver;cursor:default;font-family:sans-serif;color:#444;pointer-events:auto}.picker_wrapper:focus{outline:none}.picker_wrapper button,.picker_wrapper input{box-sizing:border-box;border:none;box-shadow:0 0 0 1px silver;outline:none}.picker_wrapper button:focus,.picker_wrapper button:active,.picker_wrapper input:focus,.picker_wrapper input:active{box-shadow:0 0 2px 1px #1e90ff}.picker_wrapper button{padding:.4em .6em;cursor:pointer;background-color:#f5f5f5;background-image:linear-gradient(0deg, gainsboro, transparent)}.picker_wrapper button:active{background-image:linear-gradient(0deg, transparent, gainsboro)}.picker_wrapper button:hover{background-color:#fff}.picker_selector{position:absolute;z-index:1;display:block;-webkit-transform:translate(-50%, -50%);transform:translate(-50%, -50%);border:2px solid #fff;border-radius:100%;box-shadow:0 0 3px 1px #67b9ff;background:currentColor;cursor:pointer}.picker_slider .picker_selector{border-radius:2px}.picker_hue{position:relative;background-image:linear-gradient(90deg, red, yellow, lime, cyan, blue, magenta, red);box-shadow:0 0 0 1px silver}.picker_sl{position:relative;box-shadow:0 0 0 1px silver;background-image:linear-gradient(180deg, white, rgba(255, 255, 255, 0) 50%),linear-gradient(0deg, black, rgba(0, 0, 0, 0) 50%),linear-gradient(90deg, #808080, rgba(128, 128, 128, 0))}.picker_alpha,.picker_sample{position:relative;background:linear-gradient(45deg, lightgrey 25%, transparent 25%, transparent 75%, lightgrey 75%) 0 0/2em 2em,linear-gradient(45deg, lightgrey 25%, white 25%, white 75%, lightgrey 75%) 1em 1em/2em 2em;box-shadow:0 0 0 1px silver}.picker_alpha .picker_selector,.picker_sample .picker_selector{background:none}.picker_editor input{font-family:monospace;padding:.2em .4em}.picker_sample::before{content:\"\";position:absolute;display:block;width:100%;height:100%;background:currentColor}.picker_arrow{position:absolute;z-index:-1}.picker_wrapper.popup{position:absolute;z-index:2;margin:1.5em}.picker_wrapper.popup,.picker_wrapper.popup .picker_arrow::before,.picker_wrapper.popup .picker_arrow::after{background:#f2f2f2;box-shadow:0 0 10px 1px rgba(0,0,0,.4)}.picker_wrapper.popup .picker_arrow{width:3em;height:3em;margin:0}.picker_wrapper.popup .picker_arrow::before,.picker_wrapper.popup .picker_arrow::after{content:\"\";display:block;position:absolute;top:0;left:0;z-index:-99}.picker_wrapper.popup .picker_arrow::before{width:100%;height:100%;-webkit-transform:skew(45deg);transform:skew(45deg);-webkit-transform-origin:0 100%;transform-origin:0 100%}.picker_wrapper.popup .picker_arrow::after{width:150%;height:150%;box-shadow:none}.popup.popup_top{bottom:100%;left:0}.popup.popup_top .picker_arrow{bottom:0;left:0;-webkit-transform:rotate(-90deg);transform:rotate(-90deg)}.popup.popup_bottom{top:100%;left:0}.popup.popup_bottom .picker_arrow{top:0;left:0;-webkit-transform:rotate(90deg) scale(1, -1);transform:rotate(90deg) scale(1, -1)}.popup.popup_left{top:0;right:100%}.popup.popup_left .picker_arrow{top:0;right:0;-webkit-transform:scale(-1, 1);transform:scale(-1, 1)}.popup.popup_right{top:0;left:100%}.popup.popup_right .picker_arrow{top:0;left:0}.igv-ui-center-fixed{left:50%;top:50%;transform:translate(-50%, -50%)}.igv-container{position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;padding-top:4px;user-select:none;-webkit-user-select:none;-ms-user-select:none;min-height:160px}.igv-viewport{position:relative;margin-top:5px;line-height:1;overflow-x:hidden;overflow-y:hidden}.igv-viewport-content{position:relative;width:100%}.igv-viewport-content>canvas{position:relative;display:block}.igv-column-container{position:relative;display:flex;flex-direction:row;flex-wrap:nowrap;justify-content:flex-start;align-items:stretch;width:100%}.igv-column-shim{width:1px;margin-left:2px;margin-right:2px;background-color:#545453}.igv-axis-column{position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;box-sizing:border-box;height:100%;width:50px}.igv-axis-column>div{position:relative;margin-top:5px;width:100%}.igv-axis-column>div>div{z-index:512;position:absolute;top:8px;left:8px;width:fit-content;height:fit-content;background-color:rgba(0,0,0,0);display:grid;align-items:start;justify-items:center}.igv-axis-column>div>div>input{display:block;margin:unset;cursor:pointer}.igv-column{position:relative;position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;box-sizing:border-box;height:100%}.igv-sample-info-column{position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;box-sizing:border-box;height:100%}.igv-sample-name-column{position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;box-sizing:border-box;height:100%}.igv-scrollbar-column{position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;box-sizing:border-box;height:100%;width:14px}.igv-scrollbar-column>div{position:relative;margin-top:5px;width:14px}.igv-scrollbar-column>div>div{cursor:pointer;position:absolute;top:0;left:2px;width:8px;border-width:1px;border-style:solid;border-color:#c4c4c4;border-top-left-radius:4px;border-top-right-radius:4px;border-bottom-left-radius:4px;border-bottom-right-radius:4px}.igv-scrollbar-column>div>div:hover{background-color:#c4c4c4}.igv-track-drag-column{position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;box-sizing:border-box;height:100%;width:12px;background-color:#fff}.igv-track-drag-column>.igv-track-drag-handle{z-index:512;position:relative;cursor:pointer;margin-top:5px;width:100%;border-style:solid;border-width:0;border-top-right-radius:6px;border-bottom-right-radius:6px}.igv-track-drag-column .igv-track-drag-handle-color{background-color:#c4c4c4}.igv-track-drag-column .igv-track-drag-handle-hover-color{background-color:#787878}.igv-track-drag-column .igv-track-drag-handle-selected-color{background-color:#0963fa}.igv-track-drag-column>.igv-track-drag-shim{position:relative;margin-top:5px;width:100%;border-style:solid;border-width:0}.igv-gear-menu-column{position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;box-sizing:border-box;height:100%;width:28px}.igv-gear-menu-column>div{display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:center;margin-top:5px;width:100%;background:#fff}.igv-gear-menu-column>div>div{position:relative;margin-top:4px;width:16px;height:16px;color:#7f7f7f}.igv-gear-menu-column>div>div:hover{cursor:pointer;color:#444}.igv-vertical-center{margin:0 !important;top:50% !important;-ms-transform:translateY(-50%) !important;transform:translateY(-50%) !important}';
+   var igvCss = '.igv-ui-dropdown{cursor:default;position:absolute;top:0;left:0;z-index:2048;border-color:#7f7f7f;border-style:solid;border-width:1px;font-family:\"Open Sans\",sans-serif;font-size:small;font-weight:400;background-color:#fff}.igv-ui-dropdown>div{overflow-y:auto;overflow-x:hidden;background-color:#fff}.igv-ui-dropdown>div>div{padding:4px;width:100%;overflow-x:hidden;text-overflow:ellipsis;white-space:nowrap;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:1px;background-color:#fff}.igv-ui-dropdown>div>div:last-child{border-bottom-color:rgba(0,0,0,0);border-bottom-width:0}.igv-ui-dropdown>div>div:hover{cursor:pointer;background-color:rgba(0,0,0,.04)}.igv-ui-popover{cursor:default;position:absolute;z-index:2048;border-color:#7f7f7f;border-radius:5px;border-style:solid;border-width:1px;font-family:\"Open Sans\",sans-serif;font-size:small;background-color:#fff}.igv-ui-popover>div:first-child{display:flex;flex-direction:row;flex-wrap:nowrap;justify-content:space-between;align-items:center;width:100%;height:24px;cursor:move;border-top-width:0;border-top-left-radius:5px;border-top-right-radius:5px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee}.igv-ui-popover>div:first-child>div:first-child{margin-left:4px}.igv-ui-popover>div:first-child>div:last-child{margin-right:4px;height:12px;width:12px;color:#7f7f7f}.igv-ui-popover>div:first-child>div:last-child:hover{cursor:pointer;color:#444}.igv-ui-popover>div:last-child{user-select:text;overflow-y:auto;overflow-x:hidden;max-height:400px;max-width:800px;background-color:#fff;border-bottom-width:0;border-bottom-left-radius:5px;border-bottom-right-radius:5px}.igv-ui-popover>div:last-child>div{margin-left:4px;margin-right:4px;min-width:220px;overflow-x:hidden;text-overflow:ellipsis;white-space:nowrap}.igv-ui-popover>div:last-child>div>span{font-weight:bolder}.igv-ui-popover>div:last-child hr{width:100%}.igv-track-label-popover{position:absolute;z-index:2048;border:1px solid #7f7f7f;border-radius:5px;background:#fff;font-family:\"Open Sans\",sans-serif;font-size:small;min-width:260px;max-width:800px;box-shadow:0 2px 8px rgba(0,0,0,.12);user-select:text}.igv-track-label-popover__header{display:flex;align-items:center;justify-content:space-between;height:24px;background:#eee;border-top-left-radius:5px;border-top-right-radius:5px;border-bottom:1px solid #7f7f7f;padding:0 8px;cursor:move}.igv-track-label-popover__title{font-weight:bold;font-size:1em;white-space:nowrap;overflow:hidden;text-overflow:ellipsis}.igv-track-label-popover__close{width:14px;height:14px;color:#7f7f7f;display:flex;align-items:center;justify-content:center;border-radius:2px;cursor:pointer;transition:background .2s,color .2s;margin-left:8px}.igv-track-label-popover__close svg{width:14px;height:14px}.igv-track-label-popover__close:hover,.igv-track-label-popover__close:focus{background:#ddd;color:#444;outline:none}.igv-track-label-popover__body{max-height:400px;overflow-y:auto;padding:8px 0;background:#fff;border-bottom-left-radius:5px;border-bottom-right-radius:5px}.igv-track-label-popover__row{display:flex;align-items:baseline;margin:0 12px 4px 12px;min-width:220px;white-space:nowrap;overflow-x:hidden;text-overflow:ellipsis}.igv-track-label-popover__key{font-weight:bold;margin-right:.5em}.igv-track-label-popover__value{font-weight:normal;flex:1 1 auto;overflow-x:hidden;text-overflow:ellipsis}.igv-track-label-popover hr{width:100%;border:none;border-top:1px solid #7f7f7f;margin:8px 0}.igv-ui-alert-dialog-container{position:fixed;top:20%;left:50%;transform:translateX(-50%);z-index:2048;box-sizing:content-box;width:400px;height:200px;border-color:#7f7f7f;border-radius:5px;border-style:solid;border-width:thin;outline:none;font-family:\"Open Sans\",sans-serif;font-size:15px;font-weight:400;background-color:#fff;display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:space-between;align-items:center}.igv-ui-alert-dialog-container>div:first-child{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center;width:100%;height:24px;cursor:move;border-top-left-radius:5px;border-top-right-radius:5px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee}.igv-ui-alert-dialog-container>div:first-child div:first-child{padding-left:8px}.igv-ui-alert-dialog-container .igv-ui-alert-dialog-body{-webkit-user-select:text;-moz-user-select:text;-ms-user-select:text;user-select:text;color:#373737;width:100%;height:calc(100% - 24px - 64px);overflow-y:scroll}.igv-ui-alert-dialog-container .igv-ui-alert-dialog-body .igv-ui-alert-dialog-body-copy{margin:16px;width:auto;height:auto;overflow-wrap:break-word;word-break:break-word;background-color:#fff;border:unset}.igv-ui-alert-dialog-container>div:last-child{width:100%;margin-bottom:10px;background-color:#fff;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:center;align-items:center}.igv-ui-alert-dialog-container>div:last-child div{margin:unset;width:40px;height:30px;line-height:30px;text-align:center;color:#fff;font-family:\"Open Sans\",sans-serif;font-size:small;font-weight:400;border-color:#2b81af;border-style:solid;border-width:thin;border-radius:4px;background-color:#2b81af}.igv-ui-alert-dialog-container>div:last-child div:hover{cursor:pointer;border-color:#25597f;background-color:#25597f}.igv-ui-generic-dialog-container{box-sizing:content-box;position:fixed;top:20%;left:75%;z-index:2048;background-color:#fff;cursor:pointer;width:300px;height:fit-content;padding-bottom:16px;border-color:#7f7f7f;border-radius:5px;border-style:solid;border-width:thin;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-header{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center;width:100%;height:24px;cursor:move;border-top-left-radius:5px;border-top-right-radius:5px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-header div{margin-right:4px;margin-bottom:2px;height:12px;width:12px;color:#7f7f7f}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-header div:hover{cursor:pointer;color:#444}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-one-liner{color:#373737;width:95%;line-height:24px;text-align:left;margin-top:8px;padding-left:8px;overflow-wrap:break-word;background-color:#fff}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-label-input{margin-top:8px;width:95%;height:24px;color:#373737;line-height:24px;padding-left:8px;background-color:#fff;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-label-input>div{width:fit-content;height:100%;font-size:16px;text-align:right;padding-right:8px;background-color:#fff}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-label-input input{display:block;height:100%;width:100%;padding-left:4px;font-family:\"Open Sans\",sans-serif;font-weight:400;color:#373737;text-align:left;outline:none;border-style:solid;border-width:thin;border-color:#7f7f7f;background-color:#fff}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-label-input input{width:50%;font-size:16px}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-input{margin-top:8px;width:calc(100% - 16px);height:24px;color:#373737;line-height:24px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-input input{display:block;height:100%;width:100%;padding-left:4px;font-family:\"Open Sans\",sans-serif;font-weight:400;color:#373737;text-align:left;outline:none;border-style:solid;border-width:thin;border-color:#7f7f7f;background-color:#fff}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-input input{font-size:16px}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-input input[type=range]{width:70%;-webkit-appearance:none;background:linear-gradient(90deg, white, black);outline:none;margin:0}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-input output{display:block;height:100%;width:20%;font-size:16px}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-ok-cancel{width:100%;height:28px;padding-top:16px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-ok-cancel>div{color:#fff;font-family:\"Open Sans\",sans-serif;font-size:14px;font-weight:400;width:75px;height:28px;line-height:28px;text-align:center;border-color:rgba(0,0,0,0);border-style:solid;border-width:thin;border-radius:2px}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-ok-cancel>div:first-child{margin-left:32px;margin-right:0;background-color:#5ea4e0}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-ok-cancel>div:last-child{margin-left:0;margin-right:32px;background-color:#c4c4c4}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-ok-cancel>div:first-child:hover{cursor:pointer;background-color:#3b5c7f}.igv-ui-generic-dialog-container .igv-ui-generic-dialog-ok-cancel>div:last-child:hover{cursor:pointer;background-color:#7f7f7f}.igv-ui-generic-container{position:fixed;cursor:pointer;background-color:#fff;z-index:2048;box-sizing:content-box;width:300px;height:200px;display:flex;flex-direction:row;flex-wrap:wrap;justify-content:flex-start;align-items:center}.igv-ui-generic-container>div:nth-child(1){cursor:move;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center;height:24px;width:100%;background-color:#ddd}.igv-ui-generic-container>div:nth-child(1)>div{display:block;color:#5f5f5f;cursor:pointer;width:14px;height:14px;margin-right:8px;margin-bottom:4px}.igv-ui-colorpicker-container{background-color:#eee;height:fit-content;flex-direction:column;flex-wrap:nowrap}.igv-ui-colorpicker-container>div:nth-child(2){display:flex;flex-direction:row;flex-wrap:wrap;justify-content:flex-start;align-items:center}.igv-ui-colorpicker-container>div:nth-child(3){box-sizing:border-box;position:relative;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center;padding:.5rem;font-family:\"Open Sans\",sans-serif;font-size:1rem;font-weight:400;width:100%;border-top-style:solid;border-top-width:thin;border-top-color:#373737}.igv-ui-colorpicker-container>div:nth-child(4){width:100%;display:flex;flex-direction:row;flex-wrap:wrap;justify-content:flex-start;align-items:center}.igv-ui-color-swatch{position:relative;box-sizing:content-box;display:flex;flex-flow:row;flex-wrap:wrap;justify-content:center;align-items:center;margin:2px;width:32px;height:32px;border-style:solid;border-width:0;border-color:#fff;border-radius:3px}.igv-ui-color-swatch-shim{cursor:pointer;position:relative;box-sizing:content-box;display:flex;flex-flow:row;flex-wrap:wrap;justify-content:center;align-items:center;width:32px;height:32px;background-color:#fff;border-style:solid;border-width:thin;border-color:#fff;border-radius:4px}.igv-ui-dialog{z-index:2048;position:fixed;width:fit-content;height:fit-content;display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:flex-start;background-color:#fff;border-color:#7f7f7f;border-radius:5px;border-style:solid;border-width:thin;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400}.igv-ui-dialog .igv-ui-dialog-header{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center;width:100%;height:24px;cursor:move;border-top-left-radius:5px;border-top-right-radius:5px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee}.igv-ui-dialog .igv-ui-dialog-header div{margin-right:4px;margin-bottom:2px;height:12px;width:12px;color:#7f7f7f}.igv-ui-dialog .igv-ui-dialog-header div:hover{cursor:pointer;color:#444}.igv-ui-dialog .igv-ui-dialog-one-liner{width:95%;height:24px;line-height:24px;text-align:left;margin:8px;overflow-wrap:break-word;background-color:#fff;font-weight:bold}.igv-ui-dialog .igv-ui-dialog-ok-cancel{width:100%;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-ui-dialog .igv-ui-dialog-ok-cancel div{margin:16px;margin-top:32px;color:#fff;font-family:\"Open Sans\",sans-serif;font-size:14px;font-weight:400;width:75px;height:28px;line-height:28px;text-align:center;border-color:rgba(0,0,0,0);border-style:solid;border-width:thin;border-radius:2px}.igv-ui-dialog .igv-ui-dialog-ok-cancel div:first-child{background-color:#5ea4e0}.igv-ui-dialog .igv-ui-dialog-ok-cancel div:last-child{background-color:#c4c4c4}.igv-ui-dialog .igv-ui-dialog-ok-cancel div:first-child:hover{cursor:pointer;background-color:#3b5c7f}.igv-ui-dialog .igv-ui-dialog-ok-cancel div:last-child:hover{cursor:pointer;background-color:#7f7f7f}.igv-ui-dialog .igv-ui-dialog-ok{width:100%;height:36px;margin-top:32px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-ui-dialog .igv-ui-dialog-ok div{width:98px;height:36px;line-height:36px;text-align:center;color:#fff;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;border-color:#fff;border-style:solid;border-width:thin;border-radius:4px;background-color:#2b81af}.igv-ui-dialog .igv-ui-dialog-ok div:hover{cursor:pointer;background-color:#25597f}.igv-ui-panel,.igv-ui-panel-row,.igv-ui-panel-column{z-index:2048;background-color:#fff;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;display:flex;justify-content:flex-start;align-items:flex-start}.igv-ui-panel-column{display:flex;flex-direction:column}.igv-ui-panel-row{display:flex;flex-direction:row}.igv-ui-textbox{background-color:#fff;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;display:flex;justify-content:flex-start;align-items:flex-start}.igv-ui-table{background-color:#fff}.igv-ui-table thead{position:sticky;top:0}.igv-ui-table th{text-align:left}.igv-ui-table td{padding-right:20px}.igv-ui-table tr:hover{background-color:#add8e6}.igv-roi-seg-filter-dialog{box-sizing:content-box;position:fixed;top:20%;left:75%;transform:translateX(-50%);z-index:2048;background-color:#fff;cursor:pointer;width:350px;height:fit-content;padding-bottom:16px;border-color:#7f7f7f;border-radius:5px;border-style:solid;border-width:thin;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-roi-seg-filter-dialog__header{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center;width:100%;height:24px;cursor:move;border-top-left-radius:5px;border-top-right-radius:5px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee}.igv-roi-seg-filter-dialog__header div{margin-right:4px;margin-bottom:2px;height:12px;width:12px;color:#7f7f7f}.igv-roi-seg-filter-dialog__header div:hover{cursor:pointer;color:#444}.igv-roi-seg-filter-dialog__radio-group{margin-top:8px;display:flex;flex-direction:column;justify-content:flex-start;align-items:flex-start}.igv-roi-seg-filter-dialog__radio-group label{display:flex;align-items:center;gap:4px;cursor:pointer}.igv-roi-seg-filter-dialog__radio-group input[type=radio]{cursor:pointer}.igv-roi-seg-filter-dialog__radio-group .op{display:flex;flex-direction:row;justify-content:flex-start;align-items:center;margin-left:16px;margin-bottom:8px;gap:2px}.igv-roi-seg-filter-dialog__radio-group .op input[type=radio]{display:block;margin:0}.igv-roi-seg-filter-dialog__radio-group .op label{display:block;margin-left:4px}.igv-roi-seg-filter-dialog__one-liner{color:#373737;width:95%;line-height:24px;text-align:left;margin-top:8px;padding-left:8px;overflow-wrap:break-word;background-color:#fff}.igv-roi-seg-filter-dialog__input{margin-top:8px;width:80%;height:24px;color:#373737;line-height:24px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-roi-seg-filter-dialog__input input{display:block;height:100%;width:100%;padding-left:4px;font-family:\"Open Sans\",sans-serif;font-weight:400;color:#373737;text-align:left;outline:none;border-style:solid;border-width:thin;border-color:#7f7f7f;background-color:#fff}.igv-roi-seg-filter-dialog__input input{font-size:16px}.igv-roi-seg-filter-dialog__ok-cancel{width:100%;height:28px;padding-top:16px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-roi-seg-filter-dialog__ok-cancel>div{color:#fff;font-family:\"Open Sans\",sans-serif;font-size:14px;font-weight:400;width:75px;height:28px;line-height:28px;text-align:center;border-color:rgba(0,0,0,0);border-style:solid;border-width:thin;border-radius:2px}.igv-roi-seg-filter-dialog__ok-cancel>div:first-child{margin-left:32px;margin-right:0;background-color:#5ea4e0}.igv-roi-seg-filter-dialog__ok-cancel>div:last-child{margin-left:0;margin-right:32px;background-color:#c4c4c4}.igv-roi-seg-filter-dialog__ok-cancel>div:first-child:hover{cursor:pointer;background-color:#3b5c7f}.igv-roi-seg-filter-dialog__ok-cancel>div:first-child.disabled{cursor:not-allowed;background-color:#ccc;opacity:.6}.igv-roi-seg-filter-dialog__ok-cancel>div:first-child.disabled:hover{cursor:not-allowed;background-color:#ccc}.igv-roi-seg-filter-dialog__ok-cancel>div:last-child:hover{cursor:pointer;background-color:#7f7f7f}.igv-clear-filters__container{font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;display:flex;flex-direction:column;max-width:300px;background-color:#fff;padding:12px;gap:8px;border-color:#7f7f7f;border-radius:5px;border-style:solid;border-width:thin}.igv-clear-filters__row{display:flex;align-items:flex-start;padding:12px;gap:12px;cursor:pointer}.igv-clear-filters__row:last-of-type{border-bottom:none}.igv-clear-filters__track-container{border-bottom:1px solid #7f7f7f;padding-bottom:8px;margin-bottom:8px}.igv-clear-filters__track-container:last-of-type{border-bottom:none;margin-bottom:0}.igv-clear-filters__track-header{display:flex;align-items:center;padding:8px 12px;gap:12px;background-color:#f5f5f5;border-radius:4px;margin-bottom:4px;font-weight:500;font-size:14px}.igv-clear-filters__track-name{color:#333;font-weight:600}.igv-clear-filters__filter-checkbox{flex:0 0 16px;width:16px;height:16px;margin-top:2px;cursor:pointer}.igv-clear-filters__checkbox{flex:0 0 16px;width:16px;height:16px;margin-top:2px;cursor:pointer}.igv-clear-filters__content{display:flex;flex-direction:row;flex:1;gap:4px}.igv-clear-filters__description{color:#333;font-size:14px;line-height:1.4}.igv-clear-filters__region{color:#666;font-family:monospace;font-size:12px;line-height:1.4}.igv-clear-filters__button-container{display:flex;gap:8px;margin-top:8px}.igv-clear-filters__button{display:flex;align-items:center;justify-content:center;flex:1;padding:10px;background-color:#5ea4e0;color:#fff;border-color:rgba(0,0,0,0);border-style:solid;border-width:thin;border-radius:2px;cursor:pointer;font-size:14px;font-weight:400;transition:background-color .2s ease}.igv-clear-filters__button:hover{background-color:#3b5c7f}.igv-clear-filters__button--cancel{background-color:#c4c4c4}.igv-clear-filters__button--cancel:hover{background-color:#7f7f7f}.igv-navbar{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-between;align-items:center;box-sizing:border-box;width:100%;color:#444;font-size:12px;font-family:\"Open Sans\",sans-serif;font-weight:400;line-height:32px;padding-left:8px;padding-right:8px;margin-top:2px;margin-bottom:6px;height:32px;border-style:solid;border-radius:3px;border-width:thin;border-color:#bfbfbf;background-color:#f3f3f3}.igv-navbar .igv-navbar-left-container{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-between;align-items:center;height:32px;line-height:32px}.igv-navbar .igv-navbar-left-container .igv-logo{width:34px;height:32px;margin-right:8px}.igv-navbar .igv-navbar-left-container .igv-current-genome{height:32px;margin-left:4px;margin-right:4px;user-select:none;line-height:32px;vertical-align:middle;text-align:center}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-between;align-items:center;height:100%}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location .igv-chromosome-select-widget-container{display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:space-around;align-items:center;height:100%;width:125px;margin-right:4px}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location .igv-chromosome-select-widget-container select{display:block;cursor:pointer;width:100px;height:75%;outline:none;font-size:12px;font-family:\"Open Sans\",sans-serif;font-weight:400}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location .igv-locus-size-group{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-between;align-items:center;margin-left:8px;height:22px}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location .igv-locus-size-group .igv-search-container{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center;width:240px;height:22px;line-height:22px}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location .igv-locus-size-group .igv-search-container input.igv-search-input{cursor:text;width:85%;height:22px;line-height:22px;font-size:12px;font-family:\"Open Sans\",sans-serif;font-weight:400;text-align:left;padding-left:8px;margin-right:8px;outline:none;border-style:solid;border-radius:3px;border-width:thin;border-color:#bfbfbf;background-color:#fff}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location .igv-locus-size-group .igv-search-container .igv-search-icon-container{cursor:pointer;height:16px;width:16px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:center;align-items:center}.igv-navbar .igv-navbar-left-container .igv-navbar-genomic-location .igv-locus-size-group .igv-windowsize-panel-container{margin-left:4px;user-select:none}.igv-navbar .igv-navbar-right-container{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-between;align-items:center}.igv-navbar .igv-navbar-right-container .igv-navbar-toggle-button-container{position:relative;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center}.igv-navbar .igv-navbar-right-container .igv-navbar-toggle-button-container-hidden{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center;height:100%}.igv-navbar .igv-navbar-right-container .igv-zoom-widget{color:#737373;font-size:18px;margin-left:8px;user-select:none;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center}.igv-navbar .igv-navbar-right-container .igv-zoom-widget div{cursor:pointer;margin-left:unset;margin-right:unset}.igv-navbar .igv-navbar-right-container .igv-zoom-widget div:first-child{height:20px;width:20px;margin-left:unset;margin-right:4px}.igv-navbar .igv-navbar-right-container .igv-zoom-widget div:last-child{height:20px;width:20px;margin-left:4px;margin-right:unset}.igv-navbar .igv-navbar-right-container .igv-zoom-widget div:nth-child(even){display:block;height:fit-content}.igv-navbar .igv-navbar-right-container .igv-zoom-widget input{display:block;width:125px}.igv-navbar .igv-navbar-right-container .igv-zoom-widget svg{display:block}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-900{color:#737373;font-size:18px;height:32px;line-height:32px;margin-left:8px;user-select:none;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-900 div{cursor:pointer;margin-left:unset;margin-right:unset}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-900 div:first-child{height:20px;width:20px;margin-left:unset;margin-right:4px}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-900 div:last-child{height:20px;width:20px;margin-left:4px;margin-right:unset}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-900 div:nth-child(even){width:0;height:0;display:none}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-900 input{width:0;height:0;display:none}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-900 svg{display:block}.igv-navbar .igv-navbar-right-container .igv-zoom-widget-hidden{display:none}.igv-navbar-button{display:block;box-sizing:unset;padding-left:6px;padding-right:6px;height:18px;text-transform:capitalize;user-select:none;line-height:18px;text-align:center;vertical-align:middle;font-family:\"Open Sans\",sans-serif;font-size:11px;font-weight:200;color:#737373;background-color:#f3f3f3;border-color:#737373;border-style:solid;border-width:thin;border-radius:6px}.igv-navbar-button:hover{cursor:pointer}.igv-navbar-button-clicked{color:#fff;background-color:#737373}.igv-navbar-icon-button{cursor:pointer;position:relative;width:24px;height:24px;margin-left:4px;margin-right:4px;border:none;background-size:contain;background-repeat:no-repeat;background-position:center}.igv-navbar-icon-button>div:first-child{z-index:512;position:absolute;top:36px;left:-18px;width:24px;height:24px;border:none;background-size:contain;background-repeat:no-repeat;background-position:center}.igv-navbar-icon-button>div:last-child{z-index:512;position:absolute;top:36px;left:18px;width:24px;height:24px;border:none;background-size:contain;background-repeat:no-repeat;background-position:center}.igv-navbar-text-button{cursor:pointer;position:relative;margin-left:2px;margin-right:2px;border:none;display:flex;justify-content:center;align-items:center}.igv-navbar-text-button>div:nth-child(2){z-index:512;position:absolute;top:36px;left:0;width:38px;height:18px;border:none;background-size:contain;background-repeat:no-repeat;background-position:center}.igv-navbar-text-button>div:nth-child(3){z-index:512;position:absolute;top:36px;left:42px;width:38px;height:18px;border:none;background-size:contain;background-repeat:no-repeat;background-position:center}#igv-text-button-label{text-anchor:middle;dominant-baseline:middle}.igv-navbar-text-button-svg-inactive rect{stroke:#737373;fill:#fff}.igv-navbar-text-button-svg-inactive text{fill:#737373}.igv-navbar-text-button-svg-inactive tspan{dominant-baseline:middle}.igv-navbar-text-button-svg-hover rect{stroke:#737373;fill:#737373}.igv-navbar-text-button-svg-hover text{fill:#fff}.igv-navbar-text-button-svg-hover tspan{dominant-baseline:middle}#igv-save-svg-group rect{stroke:#737373;fill:#fff}#igv-save-svg-group text{fill:#737373}#igv-save-svg-group:hover rect{stroke:#737373;fill:#737373}#igv-save-svg-group:hover text{fill:#fff}#igv-save-png-group rect{stroke:#737373;fill:#fff}#igv-save-png-group text{fill:#737373}#igv-save-png-group:hover rect{stroke:#737373;fill:#737373}#igv-save-png-group:hover text{fill:#fff}.igv-zoom-in-notice-container{z-index:256;position:absolute;top:8px;left:50%;transform:translate(-50%, 0%);display:flex;flex-direction:row;flex-wrap:nowrap;justify-content:center;align-items:center;background-color:#fff}.igv-zoom-in-notice-container>div{padding-left:4px;padding-right:4px;padding-top:2px;padding-bottom:2px;width:100%;height:100%;font-family:\"Open Sans\",sans-serif;font-size:14px;font-weight:400;color:#3f3f3f}.igv-zoom-in-notice{position:absolute;top:10px;left:50%}.igv-zoom-in-notice div{position:relative;left:-50%;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;color:#3f3f3f;background-color:hsla(0,0%,100%,.51);z-index:64}.igv-container-spinner{position:absolute;top:90%;left:50%;transform:translate(-50%, -50%);z-index:1024;width:24px;height:24px;pointer-events:none;color:#737373}.igv-multi-locus-close-button{position:absolute;top:2px;right:0;padding-left:2px;padding-right:2px;width:12px;height:12px;color:#666;background-color:#fff;z-index:1000}.igv-multi-locus-close-button>svg{vertical-align:top}.igv-multi-locus-close-button:hover{cursor:pointer;color:#434343}.igv-multi-locus-ruler-label{z-index:64;position:absolute;top:2px;left:0;width:100%;height:12px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:center;align-items:center}.igv-multi-locus-ruler-label>div{font-family:\"Open Sans\",sans-serif;font-size:12px;color:#101010;background-color:#fff}.igv-multi-locus-ruler-label>div{cursor:pointer}.igv-multi-locus-ruler-label-square-dot{z-index:64;position:absolute;left:50%;top:5%;transform:translate(-50%, 0%);background-color:#fff;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-multi-locus-ruler-label-square-dot>div:first-child{width:14px;height:14px}.igv-multi-locus-ruler-label-square-dot>div:last-child{margin-left:16px;font-family:\"Open Sans\",sans-serif;font-size:14px;font-weight:400;color:#101010}.igv-ruler-sweeper{display:none;pointer-events:none;position:absolute;top:26px;bottom:0;left:0;width:0;z-index:99999;background-color:rgba(68,134,247,.25)}.igv-ruler-tooltip{pointer-events:none;z-index:128;position:absolute;top:0;left:0;width:1px;height:32px;background-color:rgba(0,0,0,0);display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-ruler-tooltip>div{pointer-events:none;width:128px;height:auto;padding:1px;color:#373737;font-size:10px;font-family:\"Open Sans\",sans-serif;font-weight:400;background-color:#fff;border-style:solid;border-width:thin;border-color:#373737}.igv-track-label{position:absolute;left:8px;top:8px;width:auto;height:auto;max-width:50%;padding-left:4px;padding-right:4px;white-space:nowrap;overflow:hidden;text-overflow:ellipsis;font-family:\"Open Sans\",sans-serif;font-size:small;font-weight:400;text-align:center;user-select:none;-moz-user-select:none;-webkit-user-select:none;border-color:#444;border-radius:2px;border-style:solid;border-width:thin;background-color:#fff;z-index:128;cursor:pointer}.igv-track-label:hover,.igv-track-label:focus,.igv-track-label:active{background-color:#e8e8e8}.igv-track-label-popup-shim{position:absolute;right:8px;top:8px;width:auto;height:auto;max-width:50%;padding-left:4px;padding-right:4px;white-space:nowrap;overflow:hidden;text-overflow:ellipsis;font-family:\"Open Sans\",sans-serif;font-size:small;font-weight:400;text-align:center;user-select:none;-moz-user-select:none;-webkit-user-select:none;border-color:#444;border-radius:2px;border-style:solid;border-width:thin;background-color:#fff;z-index:128}.igv-attribute-group-label{position:absolute;right:5px;z-index:128;width:auto;height:auto;max-width:50%;padding-left:4px;padding-right:4px;white-space:nowrap;overflow:hidden;text-overflow:ellipsis;font-family:\"Open Sans\",sans-serif;font-size:small;font-weight:400;text-align:center;user-select:none;-moz-user-select:none;-webkit-user-select:none;border-color:#444;border-radius:2px;border-style:solid;border-width:thin;background-color:#fff}.igv-attribute-group-line{position:absolute;left:0px;width:100%;height:1px;background-color:rgba(0,0,0,0);border-top:1px dotted #666;pointer-events:none;z-index:127}.igv-center-line{display:none;pointer-events:none;position:absolute;top:0;bottom:0;left:50%;transform:translateX(-50%);z-index:8;user-select:none;-moz-user-select:none;-webkit-user-select:none;border-left-style:dashed;border-left-width:thin;border-right-style:dashed;border-right-width:thin}.igv-center-line-wide{background-color:rgba(0,0,0,0);border-left-color:rgba(127,127,127,.51);border-right-color:rgba(127,127,127,.51)}.igv-center-line-thin{background-color:rgba(0,0,0,0);border-left-color:rgba(127,127,127,.51);border-right-color:rgba(0,0,0,0)}.igv-cursor-guide-horizontal{display:none;pointer-events:none;user-select:none;-moz-user-select:none;-webkit-user-select:none;position:absolute;left:0;right:0;top:50%;height:1px;z-index:32;margin-left:50px;margin-right:54px;border-top-style:dotted;border-top-width:thin;border-top-color:rgba(127,127,127,.76)}.igv-cursor-guide-vertical{pointer-events:none;user-select:none;-moz-user-select:none;-webkit-user-select:none;position:absolute;top:0;bottom:0;left:50%;width:1px;z-index:32;border-left-style:dotted;border-left-width:thin;border-left-color:rgba(127,127,127,.76);display:none}.igv-user-feedback{position:fixed;top:50%;left:50%;transform:translate(-50%, -50%);width:512px;height:360px;z-index:2048;background-color:#fff;border-color:#a2a2a2;border-style:solid;border-width:thin;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;color:#444;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-user-feedback div:first-child{position:relative;height:24px;width:100%;background-color:#fff;border-bottom-color:#a2a2a2;border-bottom-style:solid;border-bottom-width:thin}.igv-user-feedback div:first-child div{position:absolute;top:2px;width:16px;height:16px;background-color:rgba(0,0,0,0)}.igv-user-feedback div:first-child div:first-child{left:8px}.igv-user-feedback div:first-child div:last-child{cursor:pointer;right:8px}.igv-user-feedback div:last-child{width:100%;height:calc(100% - 24px);border-width:0}.igv-user-feedback div:last-child div{width:auto;height:auto;margin:8px}.igv-generic-dialog-container{position:fixed;top:20%;left:75%;width:300px;height:200px;border-color:#7f7f7f;border-radius:4px;border-style:solid;border-width:thin;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;z-index:2048;background-color:#fff;display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-generic-dialog-container .igv-generic-dialog-header{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center;width:100%;height:24px;cursor:move;border-top-left-radius:4px;border-top-right-radius:4px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee}.igv-generic-dialog-container .igv-generic-dialog-header div{margin-right:4px;margin-bottom:2px;height:12px;width:12px;color:#7f7f7f}.igv-generic-dialog-container .igv-generic-dialog-header div:hover{cursor:pointer;color:#444}.igv-generic-dialog-container .igv-generic-dialog-one-liner{color:#373737;width:95%;height:24px;line-height:24px;text-align:left;margin-top:8px;padding-left:8px;overflow-wrap:break-word;background-color:#fff}.igv-generic-dialog-container .igv-generic-dialog-label-input{margin-top:8px;width:95%;height:24px;color:#373737;line-height:24px;padding-left:8px;background-color:#fff;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center}.igv-generic-dialog-container .igv-generic-dialog-label-input div{width:30%;height:100%;font-size:16px;text-align:right;padding-right:8px;background-color:#fff}.igv-generic-dialog-container .igv-generic-dialog-label-input input{display:block;height:100%;width:100%;padding-left:4px;font-family:\"Open Sans\",sans-serif;font-weight:400;color:#373737;text-align:left;outline:none;border-style:solid;border-width:thin;border-color:#7f7f7f;background-color:#fff}.igv-generic-dialog-container .igv-generic-dialog-label-input input{width:50%;font-size:16px}.igv-generic-dialog-container .igv-generic-dialog-input{margin-top:8px;width:calc(100% - 16px);height:24px;color:#373737;line-height:24px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-generic-dialog-container .igv-generic-dialog-input input{display:block;height:100%;width:100%;padding-left:4px;font-family:\"Open Sans\",sans-serif;font-weight:400;color:#373737;text-align:left;outline:none;border-style:solid;border-width:thin;border-color:#7f7f7f;background-color:#fff}.igv-generic-dialog-container .igv-generic-dialog-input input{font-size:16px}.igv-generic-dialog-container .igv-generic-dialog-ok-cancel{width:100%;height:28px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-generic-dialog-container .igv-generic-dialog-ok-cancel div{margin-top:32px;color:#fff;font-family:\"Open Sans\",sans-serif;font-size:14px;font-weight:400;width:75px;height:28px;line-height:28px;text-align:center;border-color:rgba(0,0,0,0);border-style:solid;border-width:thin;border-radius:2px}.igv-generic-dialog-container .igv-generic-dialog-ok-cancel div:first-child{margin-left:32px;margin-right:0;background-color:#5ea4e0}.igv-generic-dialog-container .igv-generic-dialog-ok-cancel div:last-child{margin-left:0;margin-right:32px;background-color:#c4c4c4}.igv-generic-dialog-container .igv-generic-dialog-ok-cancel div:first-child:hover{cursor:pointer;background-color:#3b5c7f}.igv-generic-dialog-container .igv-generic-dialog-ok-cancel div:last-child:hover{cursor:pointer;background-color:#7f7f7f}.igv-generic-dialog-container .igv-generic-dialog-ok{width:100%;height:36px;margin-top:32px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-generic-dialog-container .igv-generic-dialog-ok div{width:98px;height:36px;line-height:36px;text-align:center;color:#fff;font-family:\"Open Sans\",sans-serif;font-size:medium;font-weight:400;border-color:#fff;border-style:solid;border-width:thin;border-radius:4px;background-color:#2b81af}.igv-generic-dialog-container .igv-generic-dialog-ok div:hover{cursor:pointer;background-color:#25597f}.igv-generic-container{position:fixed;top:20%;left:75%;transform:translateX(-50%);z-index:2048;background-color:#fff;cursor:pointer;display:flex;flex-direction:row;flex-wrap:wrap;justify-content:flex-start;align-items:center}.igv-generic-container>div:nth-child(1){cursor:move;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center;height:24px;width:100%;background-color:#ddd}.igv-generic-container>div:nth-child(1) i{display:block;color:#5f5f5f;cursor:pointer;width:14px;height:14px;margin-right:8px;margin-bottom:4px}.igv-menu-popup{position:absolute;top:0;left:0;width:max-content;max-width:400px;z-index:2048;cursor:pointer;font-family:\"Open Sans\",sans-serif;font-size:small;font-weight:400;color:#4b4b4b;background:#fff;border-radius:4px;border-color:#7f7f7f;border-style:solid;border-width:thin;display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-end;text-align:left}.igv-menu-popup>div:not(:first-child){width:100%}.igv-menu-popup>div:not(:first-child)>div{background:#fff}.igv-menu-popup>div:not(:first-child)>div.context-menu{padding-left:4px;padding-right:4px}.igv-menu-popup>div:not(:first-child)>div:last-child{border-bottom-left-radius:4px;border-bottom-right-radius:4px;border-bottom-color:rgba(0,0,0,0);border-bottom-style:solid;border-bottom-width:thin}.igv-menu-popup>div:not(:first-child)>div:hover{background:#efefef}.igv-menu-popup-shim{padding-left:8px;padding-right:8px;padding-bottom:1px;padding-top:1px}.igv-menu-popup-header{position:relative;width:100%;height:24px;cursor:move;border-top-color:rgba(0,0,0,0);border-top-left-radius:4px;border-top-right-radius:4px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center}.igv-menu-popup-header div{margin-right:4px;height:12px;width:12px;color:#7f7f7f}.igv-menu-popup-header div:hover{cursor:pointer;color:#444}.igv-menu-popup-check-container{display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-start;align-items:center;width:100%;height:20px;margin-right:4px;background-color:rgba(0,0,0,0)}.igv-menu-popup-check-container div{padding-top:2px;padding-left:8px}.igv-menu-popup-check-container div:first-child{position:relative;width:12px;height:12px}.igv-menu-popup-check-container div:first-child svg{position:absolute;width:12px;height:12px}.igv-loading-spinner-container{z-index:1024;position:absolute;top:50%;left:50%;transform:translate(-50%, -50%);width:32px;height:32px;display:flex;flex-direction:row;flex-wrap:nowrap;justify-content:center;align-items:center}.igv-loading-spinner-container>div{box-sizing:border-box;width:100%;height:100%;border-radius:50%;border:4px solid rgba(128,128,128,.5);border-top-color:#fff;animation:spin 1s ease-in-out infinite;-webkit-animation:spin 1s ease-in-out infinite}@keyframes spin{to{-webkit-transform:rotate(360deg);transform:rotate(360deg)}}@-webkit-keyframes spin{to{-webkit-transform:rotate(360deg);transform:rotate(360deg)}}.igv-roi-menu{position:absolute;z-index:512;font-family:\"Open Sans\",sans-serif;font-size:small;font-weight:400;color:#4b4b4b;background-color:#fff;width:192px;border-radius:4px;border-color:#7f7f7f;border-style:solid;border-width:thin;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:stretch}.igv-roi-menu>div:first-child{height:24px;border-top-color:rgba(0,0,0,0);border-top-left-radius:4px;border-top-right-radius:4px;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:flex-end;align-items:center}.igv-roi-menu>div:first-child>div{margin-right:4px;height:12px;width:12px;color:#7f7f7f}.igv-roi-menu>div:first-child>div:hover{cursor:pointer;color:#444}.igv-roi-menu>div:last-child{background-color:#fff;border-bottom-left-radius:4px;border-bottom-right-radius:4px;border-bottom-color:rgba(0,0,0,0);border-bottom-style:solid;border-bottom-width:0;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:stretch;text-align:start;vertical-align:middle}.igv-roi-menu>div:last-child>div{height:24px;padding-left:4px;border-bottom-style:solid;border-bottom-width:thin;border-bottom-color:#7f7f7f}.igv-roi-menu>div:last-child>div:not(:first-child):hover{cursor:pointer;background-color:rgba(127,127,127,.1)}.igv-roi-menu>div:last-child div:first-child{font-style:italic;text-align:center;padding-right:4px;white-space:nowrap;overflow:hidden;text-overflow:ellipsis}.igv-roi-menu>div:last-child>div:last-child{border-bottom-width:0;border-bottom-color:rgba(0,0,0,0)}.igv-roi-placeholder{font-style:normal;color:rgba(75,75,75,.6)}.igv-roi-table{position:absolute;z-index:1024;display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:flex-start;align-items:stretch;resize:both;overflow:hidden;width:min-content;max-width:1600px;border-color:#7f7f7f;border-radius:4px;border-style:solid;border-width:thin;font-family:\"Open Sans\",sans-serif;font-size:12px;font-weight:400;background-color:#fff}.igv-roi-table>div{height:24px;font-size:14px;text-align:start;vertical-align:middle;line-height:24px}.igv-roi-table>div:first-child{border-color:rgba(0,0,0,0);border-top-left-radius:4px;border-top-right-radius:4px;border-top-width:0;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin;background-color:#eee;cursor:move;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-between;align-items:center}.igv-roi-table>div:first-child>div:first-child{text-align:center;white-space:nowrap;text-overflow:ellipsis;overflow:hidden;margin-left:4px;margin-right:4px;width:calc(100% - 4px - 12px)}.igv-roi-table>div:first-child>div:last-child{margin-right:4px;margin-bottom:2px;height:12px;width:12px;color:#7f7f7f}.igv-roi-table>div:first-child>div:last-child>svg{display:block}.igv-roi-table>div:first-child>div:last-child:hover{cursor:pointer;color:#444}.igv-roi-table{cursor:default}.igv-roi-table>.igv-roi-table-description{padding:4px;margin-left:4px;word-break:break-all;overflow-y:auto;display:flex;flex-flow:row;flex-wrap:nowrap;background-color:rgba(0,0,0,0)}.igv-roi-table>.igv-roi-table-goto-explainer{margin-top:5px;margin-left:4px;color:#7f7f7f;font-style:italic;height:24px;border-top:solid #d3d3d3;background-color:rgba(0,0,0,0)}.igv-roi-table>.igv-roi-table-column-titles{height:24px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:stretch;align-items:stretch;padding-right:16px;background-color:#fff;border-top-color:#7f7f7f;border-top-style:solid;border-top-width:thin;border-bottom-color:#7f7f7f;border-bottom-style:solid;border-bottom-width:thin}.igv-roi-table>.igv-roi-table-column-titles>div{font-size:14px;vertical-align:middle;line-height:24px;text-align:left;margin-left:4px;height:24px;overflow:hidden;text-overflow:ellipsis;border-right-color:#7f7f7f;border-right-style:solid;border-right-width:thin}.igv-roi-table>.igv-roi-table-column-titles>div:last-child{border-right:unset}.igv-roi-table>.igv-roi-table-row-container{display:flex;flex-flow:column;flex-wrap:nowrap;justify-content:flex-start;align-items:stretch;overflow:auto;height:360px;flex:1 1 auto;background-color:rgba(0,0,0,0)}.igv-roi-table>.igv-roi-table-row-container>.igv-roi-table-row{height:24px;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:stretch;align-items:stretch}.igv-roi-table>.igv-roi-table-row-container>.igv-roi-table-row>div{font-size:14px;vertical-align:middle;line-height:24px;text-align:left;margin-left:4px;height:24px;white-space:nowrap;overflow:hidden;text-overflow:ellipsis;border-right-color:rgba(0,0,0,0);border-right-style:solid;border-right-width:thin}.igv-roi-table>.igv-roi-table-row-container>.igv-roi-table-row>div:last-child{border-right:unset}.igv-roi-table>.igv-roi-table-row-container>.igv-roi-table-row-hover{background-color:rgba(0,0,0,.04)}.igv-roi-table>div:last-child{min-height:32px;height:32px;line-height:32px;border-top-color:#7f7f7f;border-top-style:solid;border-top-width:thin;border-bottom-color:rgba(0,0,0,0);border-bottom-left-radius:4px;border-bottom-right-radius:4px;border-bottom-width:0;background-color:#eee;display:flex;flex-flow:row;flex-wrap:nowrap;justify-content:space-around;align-items:center}.igv-roi-table-row-selected{background-color:rgba(0,0,0,.125)}.igv-roi-table-button{cursor:pointer;height:20px;user-select:none;line-height:20px;text-align:center;vertical-align:middle;font-family:\"Open Sans\",sans-serif;font-size:13px;font-weight:400;color:#000;padding-left:6px;padding-right:6px;background-color:#efefef;border-color:#000;border-style:solid;border-width:thin;border-radius:3px}.igv-roi-table-button:hover{font-weight:400;background-color:rgba(0,0,0,.13)}.igv-roi-region{z-index:64;position:absolute;top:0;bottom:0;pointer-events:none;overflow:visible;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:stretch}.igv-roi-region>div{position:relative;width:100%;height:8px;pointer-events:auto}.igv-roi-menu-row{height:24px;padding-left:8px;font-size:small;text-align:start;vertical-align:middle;line-height:24px;background-color:#fff}.igv-roi-menu-row-edit-description{width:-webkit-fill-available;font-size:small;text-align:start;vertical-align:middle;background-color:#fff;padding-left:4px;padding-right:4px;padding-bottom:4px;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:stretch;align-items:stretch}.igv-roi-menu-row-edit-description>label{margin-left:2px;margin-bottom:0;display:block;width:-webkit-fill-available}.igv-roi-menu-row-edit-description>input{display:block;margin-left:2px;margin-right:2px;margin-bottom:1px;width:-webkit-fill-available}.picker_wrapper.no_alpha .picker_alpha{display:none}.picker_wrapper.no_editor .picker_editor{position:absolute;z-index:-1;opacity:0}.picker_wrapper.no_cancel .picker_cancel{display:none}.layout_default.picker_wrapper{display:flex;flex-flow:row wrap;justify-content:space-between;align-items:stretch;font-size:10px;width:25em;padding:.5em}.layout_default.picker_wrapper input,.layout_default.picker_wrapper button{font-size:1rem}.layout_default.picker_wrapper>*{margin:.5em}.layout_default.picker_wrapper::before{content:\"\";display:block;width:100%;height:0;order:1}.layout_default .picker_slider,.layout_default .picker_selector{padding:1em}.layout_default .picker_hue{width:100%}.layout_default .picker_sl{flex:1 1 auto}.layout_default .picker_sl::before{content:\"\";display:block;padding-bottom:100%}.layout_default .picker_editor{order:1;width:6.5rem}.layout_default .picker_editor input{width:100%;height:100%}.layout_default .picker_sample{order:1;flex:1 1 auto}.layout_default .picker_done,.layout_default .picker_cancel{order:1}.picker_wrapper{box-sizing:border-box;background:#f2f2f2;box-shadow:0 0 0 1px silver;cursor:default;font-family:sans-serif;color:#444;pointer-events:auto}.picker_wrapper:focus{outline:none}.picker_wrapper button,.picker_wrapper input{box-sizing:border-box;border:none;box-shadow:0 0 0 1px silver;outline:none}.picker_wrapper button:focus,.picker_wrapper button:active,.picker_wrapper input:focus,.picker_wrapper input:active{box-shadow:0 0 2px 1px #1e90ff}.picker_wrapper button{padding:.4em .6em;cursor:pointer;background-color:#f5f5f5;background-image:linear-gradient(0deg, gainsboro, transparent)}.picker_wrapper button:active{background-image:linear-gradient(0deg, transparent, gainsboro)}.picker_wrapper button:hover{background-color:#fff}.picker_selector{position:absolute;z-index:1;display:block;-webkit-transform:translate(-50%, -50%);transform:translate(-50%, -50%);border:2px solid #fff;border-radius:100%;box-shadow:0 0 3px 1px #67b9ff;background:currentColor;cursor:pointer}.picker_slider .picker_selector{border-radius:2px}.picker_hue{position:relative;background-image:linear-gradient(90deg, red, yellow, lime, cyan, blue, magenta, red);box-shadow:0 0 0 1px silver}.picker_sl{position:relative;box-shadow:0 0 0 1px silver;background-image:linear-gradient(180deg, white, rgba(255, 255, 255, 0) 50%),linear-gradient(0deg, black, rgba(0, 0, 0, 0) 50%),linear-gradient(90deg, #808080, rgba(128, 128, 128, 0))}.picker_alpha,.picker_sample{position:relative;background:linear-gradient(45deg, lightgrey 25%, transparent 25%, transparent 75%, lightgrey 75%) 0 0/2em 2em,linear-gradient(45deg, lightgrey 25%, white 25%, white 75%, lightgrey 75%) 1em 1em/2em 2em;box-shadow:0 0 0 1px silver}.picker_alpha .picker_selector,.picker_sample .picker_selector{background:none}.picker_editor input{font-family:monospace;padding:.2em .4em}.picker_sample::before{content:\"\";position:absolute;display:block;width:100%;height:100%;background:currentColor}.picker_arrow{position:absolute;z-index:-1}.picker_wrapper.popup{position:absolute;z-index:2;margin:1.5em}.picker_wrapper.popup,.picker_wrapper.popup .picker_arrow::before,.picker_wrapper.popup .picker_arrow::after{background:#f2f2f2;box-shadow:0 0 10px 1px rgba(0,0,0,.4)}.picker_wrapper.popup .picker_arrow{width:3em;height:3em;margin:0}.picker_wrapper.popup .picker_arrow::before,.picker_wrapper.popup .picker_arrow::after{content:\"\";display:block;position:absolute;top:0;left:0;z-index:-99}.picker_wrapper.popup .picker_arrow::before{width:100%;height:100%;-webkit-transform:skew(45deg);transform:skew(45deg);-webkit-transform-origin:0 100%;transform-origin:0 100%}.picker_wrapper.popup .picker_arrow::after{width:150%;height:150%;box-shadow:none}.popup.popup_top{bottom:100%;left:0}.popup.popup_top .picker_arrow{bottom:0;left:0;-webkit-transform:rotate(-90deg);transform:rotate(-90deg)}.popup.popup_bottom{top:100%;left:0}.popup.popup_bottom .picker_arrow{top:0;left:0;-webkit-transform:rotate(90deg) scale(1, -1);transform:rotate(90deg) scale(1, -1)}.popup.popup_left{top:0;right:100%}.popup.popup_left .picker_arrow{top:0;right:0;-webkit-transform:scale(-1, 1);transform:scale(-1, 1)}.popup.popup_right{top:0;left:100%}.popup.popup_right .picker_arrow{top:0;left:0}.igv-ui-center-fixed{left:50%;top:50%;transform:translate(-50%, -50%)}.igv-container{all:initial;position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;padding-top:4px;user-select:none;-webkit-user-select:none;-ms-user-select:none;min-height:160px}.igv-viewport{position:relative;margin-top:5px;line-height:1;overflow-x:hidden;overflow-y:hidden}.igv-viewport-content{position:relative;width:100%}.igv-viewport-content>canvas{position:relative;display:block}.igv-column-container{position:relative;display:flex;flex-direction:row;flex-wrap:nowrap;justify-content:flex-start;align-items:stretch;width:100%}.igv-column-shim{width:1px;margin-left:2px;margin-right:2px;background-color:#545453}.igv-axis-column{position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;box-sizing:border-box;height:100%;width:50px}.igv-axis-column>div{position:relative;margin-top:5px;width:100%}.igv-axis-column>div>div{z-index:512;position:absolute;top:8px;left:8px;width:fit-content;height:fit-content;background-color:rgba(0,0,0,0);display:grid;align-items:start;justify-items:center}.igv-axis-column>div>div>input{display:block;margin:unset;cursor:pointer}.igv-column{position:relative;flex:auto;position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;box-sizing:border-box;height:100%}.igv-sample-info-column{position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;box-sizing:border-box;height:100%}.igv-sample-name-column{position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;box-sizing:border-box;height:100%}.igv-scrollbar-column{position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;box-sizing:border-box;height:100%;width:14px}.igv-scrollbar-column>div{position:relative;margin-top:5px;width:14px}.igv-scrollbar-column>div>div{cursor:pointer;position:absolute;top:0;left:2px;width:8px;border-width:1px;border-style:solid;border-color:#c4c4c4;border-top-left-radius:4px;border-top-right-radius:4px;border-bottom-left-radius:4px;border-bottom-right-radius:4px}.igv-scrollbar-column>div>div:hover{background-color:#c4c4c4}.igv-track-drag-column{position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;box-sizing:border-box;height:100%;width:12px;background-color:#fff}.igv-track-drag-column>.igv-track-drag-handle{z-index:512;position:relative;cursor:pointer;margin-top:5px;width:100%;border-style:solid;border-width:0;border-top-right-radius:6px;border-bottom-right-radius:6px}.igv-track-drag-column .igv-track-drag-handle-color{background-color:#c4c4c4}.igv-track-drag-column .igv-track-drag-handle-hover-color{background-color:#787878}.igv-track-drag-column .igv-track-drag-handle-selected-color{background-color:#0963fa}.igv-track-drag-column>.igv-track-drag-shim{position:relative;margin-top:5px;width:100%;border-style:solid;border-width:0}.igv-gear-menu-column{position:relative;display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:flex-start;box-sizing:border-box;height:100%;width:28px}.igv-gear-menu-column>div{display:flex;flex-direction:column;flex-wrap:nowrap;justify-content:flex-start;align-items:center;margin-top:5px;width:100%;background:#fff}.igv-gear-menu-column>div>div{position:relative;margin-top:4px;width:16px;height:16px;color:#7f7f7f}.igv-gear-menu-column>div>div:hover{cursor:pointer;color:#444}.igv-vertical-center{margin:0 !important;top:50% !important;-ms-transform:translateY(-50%) !important;transform:translateY(-50%) !important}';
 
    /**
     * Manages XQTL selections.
@@ -73474,6 +73662,68 @@ ${indent}columns: ${matrix.columns}
        }
    }
 
+   class EventEmitter {
+
+
+       constructor() {
+           // Map of event name -> [ handlerFn, ... ]
+           this.eventHandlers = new Map();
+       }
+
+       on(eventName, fn) {
+           if (!this.eventHandlers.has(eventName)) {
+               this.eventHandlers.set(eventName, []);
+           }
+           this.eventHandlers.get(eventName).push(fn);
+       }
+
+
+       /**
+        * @deprecated use off()
+        * @param eventName
+        * @param fn
+        */
+       un(eventName, fn) {
+           this.off(eventName, fn);
+       }
+
+
+       off(eventName, fn) {
+
+           if (!eventName) {
+               this.eventHandlers.clear();   // Remove all event handlers
+           } else if (!fn) {
+               this.eventHandlers.delete(eventName); // Remove all eventhandlers matching name
+           } else {
+               // Remove specific event handler
+               const handlers = this.eventHandlers.get(eventName);
+               if (!handlers || handlers.length === 0) {
+                   console.warn("No handlers to remove for event: " + eventName);
+               } else {
+                   const callbackIndex = handlers.indexOf(fn);
+                   if (callbackIndex !== -1) {
+                       handlers.splice(callbackIndex, 1);
+                   }
+               }
+           }
+       }
+
+       emit(eventName, args, thisObj) {
+
+           const handlers = this.eventHandlers.get(eventName);
+           if (undefined === handlers || handlers.length === 0) {
+               return undefined
+           }
+
+           const scope = thisObj || globalThis;
+           const results = handlers.map(function (handler) {
+               return handler.apply(scope, args)
+           });
+
+           return results
+       }
+   }
+
    // css - $igv-scrollbar-outer-width: 14px;
    const igv_scrollbar_outer_width = 14;
 
@@ -73496,8 +73746,8 @@ ${indent}columns: ${matrix.columns}
            this.config = config;
            this.guid = guid$2();
            this.namespace = '.browser_' + this.guid;
-
            this.parent = parentDiv;
+           this.eventEmitter = new EventEmitter();
 
            let shadowRoot = parentDiv.shadowRoot;
            if (!shadowRoot) {
@@ -73531,15 +73781,14 @@ ${indent}columns: ${matrix.columns}
                doubleClickDelay: config.doubleClickDelay || 500
            };
 
-           // Map of event name -> [ handlerFn, ... ]
-           this.eventHandlers = {};
-
            if (config.listeners) {
                for (let evt of Object.keys(config.listeners)) {
                    this.on(evt, config.listeners[evt]);
                }
            }
 
+           // Events
+
            this.on('trackremoved', () => {
 
                const found = this.findTracks(track => typeof track.getSamples === 'function');
@@ -73559,7 +73808,7 @@ ${indent}columns: ${matrix.columns}
                }
            });
 
-           this.on('didchangecolumnlayout', () => {
+           this.on('columnlayoutchange', () => {
                if (trackViewportPopoverList.length > 0) {
                    const len = trackViewportPopoverList.length;
                    for (let i = 0; i < len; i++) {
@@ -73814,7 +74063,7 @@ ${indent}columns: ${matrix.columns}
 
            let session;
            if (options.url || options.file) {
-               session = await Browser.loadSessionFile(options);
+               session = await Browser.loadSessionFile(options, this.config);
                // if (options.parentApp``) {
                //     session.parentApp = options.parentApp
                // }
@@ -73831,7 +74080,7 @@ ${indent}columns: ${matrix.columns}
         * @param options
         * @returns {Promise<*|XMLSession>}
         */
-       static async loadSessionFile(options) {
+       static async loadSessionFile(options, defaults) {
 
            const urlOrFile = options.url || options.file;
 
@@ -73862,8 +74111,8 @@ ${indent}columns: ${matrix.columns}
                    throw Error("Unrecognized session file format:" + filename)
                }
            }
-           return setDefaults(config)
-
+           setDefaults(config, defaults);
+           return config
        }
 
        /**
@@ -73891,8 +74140,22 @@ ${indent}columns: ${matrix.columns}
                this.sampleNameViewportWidth = session.sampleNameViewportWidth;
            }
 
+           // Track gear column
+           if (this.config.gearColumnPosition === 'left') {
+               const gearcolumn = createColumn(this.columnContainer, 'igv-gear-menu-column');
+               if (false === this.config.showGearColumn) {
+                   gearcolumn.style.width = '0px';  // Don't use display none, need element to attach menu
+               }
+           }
+
            // axis column
-           createColumn(this.columnContainer, 'igv-axis-column');
+           const axisColumn = createColumn(this.columnContainer, 'igv-axis-column');
+           if (false === this.config.showAxis) {
+               axisColumn.style.display = 'none';
+           }
+           if (this.config.axisWidth !== undefined) {
+               axisColumn.style.width = this.config.axisWidth + 'px';
+           }
 
            // sample info column
            createColumn(this.columnContainer, 'igv-sample-info-column');
@@ -73904,10 +74167,18 @@ ${indent}columns: ${matrix.columns}
            createColumn(this.columnContainer, 'igv-scrollbar-column');
 
            // Track drag/reorder column
-           createColumn(this.columnContainer, 'igv-track-drag-column');
+           const dragColumn = createColumn(this.columnContainer, 'igv-track-drag-column');
+           if (false === this.config.showTrackDragHandles) {
+               dragColumn.style.display = 'none';
+           }
 
            // Track gear column
-           createColumn(this.columnContainer, 'igv-gear-menu-column');
+           if (this.config.gearColumnPosition !== 'left') {
+               const gearcolumn = createColumn(this.columnContainer, 'igv-gear-menu-column');
+               if (false === this.config.showGearColumn) {
+                   gearcolumn.style.width = '0px';
+               }
+           }
 
            const genomeOrReference = session.reference || session.genome;
            if (!genomeOrReference) {
@@ -73975,7 +74246,7 @@ ${indent}columns: ${matrix.columns}
 
            // Ensure that we always have a sequence track with no explicit URL (=> the reference genome sequence track)
            const pushSequenceTrack = trackConfigurations.filter(track => 'sequence' === track.type && !track.url && !track.fastaURL).length === 0;
-           if (pushSequenceTrack /*&& false !== this.config.showSequence*/) {
+           if (pushSequenceTrack && false !== this.config.showSequence) {
                trackConfigurations.push({type: "sequence", order: defaultSequenceTrackOrder, removable: false});
            }
 
@@ -74013,6 +74284,12 @@ ${indent}columns: ${matrix.columns}
 
            await this.loadTrackList(nonLocalTrackConfigurations);
 
+           // If an initial locus is defined and represents a single basedo a "search" here.  This will force micro
+           // adjustments after width of track column(s) is known.  This can be an issue when the center gide is shown
+           // Without this adjustment the single base would be off center by a few pixels.
+           if (session.locus && Locus.isSingleBaseLocusString(session.locus)) {
+               await this.search(session.locus);
+           }
        }
 
        cleanHouseForSession() {
@@ -74062,15 +74339,25 @@ ${indent}columns: ${matrix.columns}
            this.navbar.updateGenome(genome);
 
            let locus = initialLocus || genome.initialLocus;
-           if (Array.isArray(locus)) {
-               locus = locus.join(' ');
-           }
 
-           const locusFound = await this.search(locus, true);
-           if (!locusFound) {
-               console.error(`Cannot set initial locus ${locus}`);
-               if (locus !== genome.initialLocus) {
-                   await this.search(genome.initialLocus);
+           if (typeof (locus.chr) !== "undefined" && typeof (locus.start) !== "undefined") {
+
+               // Locus explicitly an object, either {chr, start, end} or {chr, start, bpPerPixel), skip search,
+               // bug must still ensure chromosome is loaded
+               await this.genome.loadChromosome(locus.chr);
+               await this.updateLoci([locus], true);
+
+           } else {
+               if (Array.isArray(locus)) {
+                   locus = locus.join(' ');
+               }
+
+               const locusFound = await this.search(locus, true);
+               if (!locusFound) {
+                   console.error(`Cannot set initial locus ${locus}`);
+                   if (locus !== genome.initialLocus) {
+                       await this.search(genome.initialLocus);
+                   }
                }
            }
 
@@ -74818,7 +75105,16 @@ ${indent}columns: ${matrix.columns}
 
            let {width} = this.columnContainer.getBoundingClientRect();
 
-           width -= igv_axis_column_width + this.getSampleInfoViewportWidth() + this.getSampleNameViewportWidth() + igv_scrollbar_outer_width + igv_track_manipulation_handle_width + igv_track_gear_menu_column_width;
+           const sampleInfoViewportWidth = this.getSampleInfoViewportWidth();
+           const sampleNameViewportWidth = this.getSampleNameViewportWidth();
+
+           width -=
+               (this.config.showAxis === false ? 0 : igv_axis_column_width) +
+               sampleInfoViewportWidth +
+               sampleNameViewportWidth +
+               igv_scrollbar_outer_width +
+               (this.config.showTrackDragHandles === false ? 0 : igv_track_manipulation_handle_width) +
+               (this.config.showGearColumn === false ? 0 : igv_track_gear_menu_column_width);
 
            width -= column_multi_locus_shim_width * (columnCount - 1);
 
@@ -74872,15 +75168,19 @@ ${indent}columns: ${matrix.columns}
        // Zoom in by a factor of 2, keeping the same center location
        zoomIn() {
            this.zoomWithScaleFactor(0.5);
-       };
+       }
+
 
        // Zoom out by a factor of 2, keeping the same center location if possible
        zoomOut() {
            this.zoomWithScaleFactor(2.0);
-       };
+       }
+
 
        async zoomWithScaleFactor(scaleFactor, centerBPOrUndefined, referenceFrameOrUndefined) {
 
+           if (this.config.disableZoom === true) return   // Useful when an embedding application wants to control zooming
+
            if (!this.referenceFrameList) return
 
            const viewportWidth = this.calculateViewportWidth(this.referenceFrameList.length);
@@ -74890,6 +75190,8 @@ ${indent}columns: ${matrix.columns}
            for (let referenceFrame of referenceFrames) {
                referenceFrame.zoomWithScaleFactor(this, scaleFactor, viewportWidth, centerBPOrUndefined);
            }
+
+           this.fireEvent("zoom", [referenceFrames]);
        }
 
        /**
@@ -74918,7 +75220,7 @@ ${indent}columns: ${matrix.columns}
            // TODO -- this is really ugly
            const {viewportElement} = this.trackViews[0].viewports[indexLeft];
            const viewportColumn = viewportColumnManager.insertAfter(viewportElement.parentElement);
-           this.fireEvent('didchangecolumnlayout');
+           this.fireEvent('columnlayoutchange');
 
            if (indexRight === this.referenceFrameList.length) {
                this.referenceFrameList.push(newReferenceFrame);
@@ -74964,7 +75266,7 @@ ${indent}columns: ${matrix.columns}
            const {viewportElement} = this.trackViews[0].viewports[index];
 
            viewportColumnManager.removeColumnAtIndex(index, viewportElement.parentElement);
-           this.fireEvent('didchangecolumnlayout');
+           this.fireEvent('columnlayoutchange');
 
            for (let {viewports} of this.trackViews) {
                viewports[index].dispose();
@@ -75088,7 +75390,7 @@ ${indent}columns: ${matrix.columns}
 
                // Insert viewport columns preceding the sample info column
                viewportColumnManager.insertBefore(this.columnContainer.querySelector('.igv-sample-info-column'), this.referenceFrameList.length);
-               this.fireEvent('didchangecolumnlayout');
+               this.fireEvent('columnlayoutchange');
 
                // Create the viewport objects -- TODO -- this is done for every search, which is insane
                for (let trackView of this.trackViews) {
@@ -75178,14 +75480,11 @@ ${indent}columns: ${matrix.columns}
        }
 
 
-   // EVENTS
+       // IGV events (not DOM events)
 
        on(eventName, fn) {
-           if (!this.eventHandlers[eventName]) {
-               this.eventHandlers[eventName] = [];
-           }
-           this.eventHandlers[eventName].push(fn);
-       };
+           this.eventEmitter.on(eventName, fn);
+       }
 
        /**
         * @deprecated use off()
@@ -75193,42 +75492,16 @@ ${indent}columns: ${matrix.columns}
         * @param fn
         */
        un(eventName, fn) {
-           this.off(eventName, fn);
-       };
+           this.eventEmitter.off(eventName, fn);
+       }
 
-       off(eventName, fn) {
 
-           if (!eventName) {
-               this.eventHandlers = {};   // Remove all event handlers
-           } else if (!fn) {
-               this.eventHandlers[eventName] = []; // Remove all eventhandlers matching name
-           } else {
-               // Remove specific event handler
-               const handlers = this.eventHandlers[eventName];
-               if (!handlers || handlers.length === 0) {
-                   console.warn("No handlers to remove for event: " + eventName);
-               } else {
-                   const callbackIndex = handlers.indexOf(fn);
-                   if (callbackIndex !== -1) {
-                       this.eventHandlers[eventName].splice(callbackIndex, 1);
-                   }
-               }
-           }
+       off(eventName, fn) {
+           this.eventEmitter.off(eventName, fn);
        }
 
        fireEvent(eventName, args, thisObj) {
-
-           const handlers = this.eventHandlers[eventName];
-           if (undefined === handlers || handlers.length === 0) {
-               return undefined
-           }
-
-           const scope = thisObj || window;
-           const results = handlers.map(function (event) {
-               return event.apply(scope, args)
-           });
-
-           return results[0]
+           return this.eventEmitter.emit(eventName, args, thisObj)
        }
 
        dispose() {
@@ -75403,7 +75676,8 @@ ${indent}columns: ${matrix.columns}
                mouseDownY: coords.y,
                referenceFrame: viewport.referenceFrame
            };
-       };
+       }
+
 
        cancelTrackPan() {
 
@@ -75650,7 +75924,9 @@ ${indent}columns: ${matrix.columns}
        }
    }
 
-   function getFileExtension(input) {
+   function
+
+   getFileExtension(input) {
        let fileName;
 
        // Check if input is a File object or a URL string
@@ -75679,7 +75955,9 @@ ${indent}columns: ${matrix.columns}
     *
     * @returns {Promise<void>}
     */
-   async function resize(event) {
+   async function
+
+   resize(event) {
 
        if (undefined === this.referenceFrameList || 0 === this.referenceFrameList.length) {
            return
@@ -75692,7 +75970,9 @@ ${indent}columns: ${matrix.columns}
    }
 
 
-   function handleMouseMove(e) {
+   function
+
+   handleMouseMove(e) {
 
        e.preventDefault();
 
@@ -75729,7 +76009,7 @@ ${indent}columns: ${matrix.columns}
                if (viewChanged) {
                    this.updateViews();
                }
-               this.fireEvent('trackdrag');
+               this.fireEvent('trackdrag', [e]);
            }
 
 
@@ -75744,7 +76024,9 @@ ${indent}columns: ${matrix.columns}
        }
    }
 
-   function mouseUpOrLeave(e) {
+   function
+
+   mouseUpOrLeave(e) {
        this.cancelTrackPan();
        this.endTrackDrag();
    }
@@ -75753,7 +76035,9 @@ ${indent}columns: ${matrix.columns}
     * Handle keyup event, used for navigating feature tracks with hot keys.  This will get bound to the browser object
     * @param event
     */
-   async function keyUpHandler(event) {
+   async function
+
+   keyUpHandler(event) {
 
        // Feature jumping disabled in multi-locus view
        if (!this.referenceFrameList || this.referenceFrameList.length > 1) return
@@ -75831,7 +76115,9 @@ ${indent}columns: ${matrix.columns}
        }
    }
 
-   function toggleTrackLabels(trackViews, isVisible) {
+   function
+
+   toggleTrackLabels(trackViews, isVisible) {
 
        for (let {viewports} of trackViews) {
            for (let viewport of viewports) {
@@ -75883,6 +76169,11 @@ ${indent}columns: ${matrix.columns}
            });
        }
 
+       // A very obscure and undocumented option unlikely to be needed by anyone but us.
+       if(config.formEmbedMode) {
+           InputDialog.FORM_EMBED_MODE = true;
+       }
+
        // Create browser
        const browser = new Browser(config, parentDiv);
        allBrowsers.push(browser);
@@ -75926,86 +76217,16 @@ ${indent}columns: ${matrix.columns}
        }
    }
 
-   function setDefaults(config) {
-
-       if (undefined === config.minimumBases) {
-           config.minimumBases = 40;
-       }
-
-       if (undefined === config.showIdeogram) {
-           config.showIdeogram = true;
-       }
-
-       if (undefined == config.showCytobandNames) {
-           config.showCytobandNames = false;
-       }
-
-       if (undefined === config.showCircularView) {
-           config.showCircularView = false;
-       }
-
-       if (undefined === config.showCircularViewButton) {
-           config.showCircularViewButton = false;
-       }
-
-       if (undefined === config.showTrackLabelButton) {
-           config.showTrackLabelButton = true;
-       }
-
-       if (undefined === config.showTrackLabels) {
-           config.showTrackLabels = true;
-       }
-
-       if (undefined === config.showCursorTrackingGuideButton) {
-           config.showCursorTrackingGuideButton = true;
-       }
-
-       if (undefined === config.showCursorGuide) {
-           config.showCursorGuide = config.showCursorTrackingGuide || false;   // showCursorTrackingGuide is a synonym
-       }
-
-       if (undefined === config.showCenterGuideButton) {
-           config.showCenterGuideButton = true;
-       }
-
-       if (undefined === config.showCenterGuide) {
-           config.showCenterGuide = false;
-       }
-
-       if (undefined === config.showSampleNames) {
-           config.showSampleNames = false;
-       }
-
-       if (undefined === config.showSVGButton) {
-           config.showSVGButton = true;
-       }
-
-       if (config.showControls === undefined) {
-           config.showControls = true;
+   function setDefaults(config, defaults) {
+       if (typeof defaults === "undefined") {
+           defaults = defaultOptions;
        }
-
-       if (config.showNavigation === undefined) {
-           config.showNavigation = true;
-       }
-
-       if (config.showRuler === undefined) {
-           config.showRuler = true;
-       }
-
-       if (config.flanking === undefined) {
-           config.flanking = 1000;
-       }
-
-       if (config.pairsSupported === undefined) {
-           config.pairsSupported = true;
-       }
-
-       if (!config.tracks) {
-           config.tracks = [];
+       for (const key of Object.keys(defaults)) {
+           if (config[key] === undefined) {
+               config[key] = defaults[key];
+           }
        }
-
        return config
-
    }
 
 
@@ -76097,6 +76318,28 @@ ${indent}columns: ${matrix.columns}
        return await Browser.prototype.createTrack.call(browser, config)
    }
 
+   const defaultOptions = {
+       minimumBases: 40,
+       showIdeogram: true,
+       showCytobandNames: false,
+       showCircularView: false,
+       showCircularViewButton: false,
+       showTrackLabelButton: true,
+       showTrackLabels: true,
+       showCursorTrackingGuideButton: true,
+       showCursorGuide: false,   // showCursorTrackingGuide is a synonym
+       showCenterGuideButton: true,
+       showCenterGuide: false,
+       showSampleNames: false,
+       showSVGButton: true,
+       showControls: true,
+       showNavigation: true,
+       showRuler: true,
+       flanking: 1000,
+       pairsSupported: true,
+       tracks: []
+   };
+
    // Defines the top-level API for the igv module
 
    const setApiKey = igvxhr.setApiKey;
@@ -76133,7 +76376,9 @@ ${indent}columns: ${matrix.columns}
        registerTrackCreatorFunction,
        registerFileFormats,
        loadSessionFile: Browser.loadSessionFile,
-       loadHub
+       loadHub,
+       uncompressSession: Browser.uncompressSession,
+       createIcon
    };
 
    return index;