heor-agent-mcp 1.10.1 → 1.11.0

package/README.md

@@ -45,7 +45,7 @@ curl -s http://localhost:8080/health
 Expected output:
 
 ```json
-{"status":"ok","server":"heor-agent-mcp","version":"1.9.2"}
+{"status":"ok","server":"heor-agent-mcp","version":"1.10.2"}
 ```
 
 ✅ If you see the JSON above, the npm package works on your machine. Any further issues are in your MCP client config (Claude Desktop / Cursor / Continue), not the server.
@@ -126,7 +126,7 @@ The first prompt exercises `literature_search` + `validate_links` (free, no API
 
 ## What's new
 
-See [CHANGELOG.md](./CHANGELOG.md) for full version history. Current: **v1.9.2** (27 tools, 44 data sources).
+See [CHANGELOG.md](./CHANGELOG.md) for full version history. Current: **v1.10.2** (28 tools, 44 data sources).
 
 ### v1.0.4 highlights (still in v1.6.3)
 

package/dist/analytics.d.ts

@@ -9,17 +9,31 @@ export type ClientSurface = "claude_anthropic_web" | "chatgpt_adapter" | "claude
 export declare function inferSurface(clientName: string | undefined): ClientSurface;
 export declare function trackEvent(event: string, properties?: Record<string, unknown>, sessionId?: string): void;
 /**
- * Extracts structured analytics properties from a thrown value. Always
- * returns the same two property names so PostHog dashboards can query
- * `properties.error_class` and `properties.error_message` reliably.
+ * Extracts structured analytics properties from a thrown value.
  *
- * - Error subclasses → constructor name + message (truncated to 500 chars)
+ * Returns THREE fields so callers can pick the right one for each surface:
+ *   - `error_class`     — constructor/category name, stable for dashboards
+ *   - `error_message`   — FULL message, no truncation. Use this for the
+ *                         client-facing response so callers (including the
+ *                         ChatGPT Custom GPT) see the complete validation
+ *                         feedback and can recover in-conversation.
+ *   - `telemetry_message` — same message capped at 500 chars. Use this for
+ *                         PostHog `properties.error_message` so we don't
+ *                         blow up event payload size on a 50KB ZodError.
+ *
+ * Why we split these (added v1.10.2): pre-v1.10.2 the capped field doubled
+ * as the client response (server.ts:475), so ChatGPT received a JSON
+ * ZodError truncated mid-key and could not recover. The 500-char cap was
+ * a telemetry-hygiene decision that quietly broke the response surface.
+ *
+ * - Error subclasses → constructor name + full message
  * - Strings / numbers / null → class="unknown", message=stringified
  * - Circular objects / weird values → class="unknown", message=safe stringify
  */
 export declare function classifyToolError(err: unknown): {
     error_class: string;
     error_message: string;
+    telemetry_message: string;
 };
 export declare function trackToolCall(toolName: string, durationMs: number, status: "ok" | "error", sessionId?: string, properties?: Record<string, unknown>): void;
 export declare function trackSession(event: "session_start" | "session_end", sessionId: string, properties?: Record<string, unknown>): void;

package/dist/analytics.d.ts.map

@@ -1 +1 @@
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+{"version":3,"file":"analytics.d.ts","sourceRoot":"","sources":["../src/analytics.ts"],"names":[],"mappings":"AAEA;;;;;;GAMG;AACH,MAAM,MAAM,aAAa,GACrB,sBAAsB,GACtB,iBAAiB,GACjB,gBAAgB,GAChB,UAAU,GACV,OAAO,GACP,UAAU,GACV,YAAY,CAAC;AAEjB,wBAAgB,YAAY,CAAC,UAAU,EAAE,MAAM,GAAG,SAAS,GAAG,aAAa,CAe1E;AAgBD,wBAAgB,UAAU,CACxB,KAAK,EAAE,MAAM,EACb,UAAU,GAAE,MAAM,CAAC,MAAM,EAAE,OAAO,CAAM,EACxC,SAAS,CAAC,EAAE,MAAM,QAanB;AAED;;;;;;;;;;;;;;;;;;;;;GAqBG;AACH,wBAAgB,iBAAiB,CAAC,GAAG,EAAE,OAAO,GAAG;IAC/C,WAAW,EAAE,MAAM,CAAC;IACpB,aAAa,EAAE,MAAM,CAAC;IACtB,iBAAiB,EAAE,MAAM,CAAC;CAC3B,CAoBA;AAED,wBAAgB,aAAa,CAC3B,QAAQ,EAAE,MAAM,EAChB,UAAU,EAAE,MAAM,EAClB,MAAM,EAAE,IAAI,GAAG,OAAO,EACtB,SAAS,CAAC,EAAE,MAAM,EAClB,UAAU,GAAE,MAAM,CAAC,MAAM,EAAE,OAAO,CAAM,QAYzC;AAED,wBAAgB,YAAY,CAC1B,KAAK,EAAE,eAAe,GAAG,aAAa,EACtC,SAAS,EAAE,MAAM,EACjB,UAAU,GAAE,MAAM,CAAC,MAAM,EAAE,OAAO,CAAM,QAGzC;AAED,wBAAsB,iBAAiB,kBAKtC"}

package/dist/analytics.js

@@ -47,19 +47,34 @@ export function trackEvent(event, properties = {}, sessionId) {
     });
 }
 /**
- * Extracts structured analytics properties from a thrown value. Always
- * returns the same two property names so PostHog dashboards can query
- * `properties.error_class` and `properties.error_message` reliably.
+ * Extracts structured analytics properties from a thrown value.
  *
- * - Error subclasses → constructor name + message (truncated to 500 chars)
+ * Returns THREE fields so callers can pick the right one for each surface:
+ *   - `error_class`     — constructor/category name, stable for dashboards
+ *   - `error_message`   — FULL message, no truncation. Use this for the
+ *                         client-facing response so callers (including the
+ *                         ChatGPT Custom GPT) see the complete validation
+ *                         feedback and can recover in-conversation.
+ *   - `telemetry_message` — same message capped at 500 chars. Use this for
+ *                         PostHog `properties.error_message` so we don't
+ *                         blow up event payload size on a 50KB ZodError.
+ *
+ * Why we split these (added v1.10.2): pre-v1.10.2 the capped field doubled
+ * as the client response (server.ts:475), so ChatGPT received a JSON
+ * ZodError truncated mid-key and could not recover. The 500-char cap was
+ * a telemetry-hygiene decision that quietly broke the response surface.
+ *
+ * - Error subclasses → constructor name + full message
  * - Strings / numbers / null → class="unknown", message=stringified
  * - Circular objects / weird values → class="unknown", message=safe stringify
  */
 export function classifyToolError(err) {
     if (err instanceof Error) {
+        const full = err.message ?? "";
         return {
             error_class: err.constructor?.name ?? "Error",
-            error_message: (err.message ?? "").slice(0, 500),
+            error_message: full,
+            telemetry_message: full.slice(0, 500),
         };
     }
     let message;
@@ -71,7 +86,8 @@ export function classifyToolError(err) {
     }
     return {
         error_class: "unknown",
-        error_message: message.slice(0, 500),
+        error_message: message,
+        telemetry_message: message.slice(0, 500),
     };
 }
 export function trackToolCall(toolName, durationMs, status, sessionId, properties = {}) {

package/dist/analytics.js.map

@@ -1 +1 @@
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+{"version":3,"file":"analytics.js","sourceRoot":"","sources":["../src/analytics.ts"],"names":[],"mappings":"AAAA,OAAO,EAAE,OAAO,EAAE,MAAM,cAAc,CAAC;AAkBvC,MAAM,UAAU,YAAY,CAAC,UAA8B;IACzD,IAAI,CAAC,UAAU;QAAE,OAAO,YAAY,CAAC;IACrC,MAAM,CAAC,GAAG,UAAU,CAAC,WAAW,EAAE,CAAC;IACnC,IAAI,CAAC,CAAC,UAAU,CAAC,aAAa,CAAC;QAAE,OAAO,sBAAsB,CAAC;IAC/D,IAAI,CAAC,CAAC,UAAU,CAAC,iBAAiB,CAAC;QAAE,OAAO,iBAAiB,CAAC;IAC9D,IACE,CAAC,KAAK,QAAQ;QACd,CAAC,CAAC,UAAU,CAAC,WAAW,CAAC;QACzB,CAAC,CAAC,UAAU,CAAC,gBAAgB,CAAC;QAE9B,OAAO,gBAAgB,CAAC;IAC1B,IAAI,CAAC,CAAC,UAAU,CAAC,UAAU,CAAC;QAAE,OAAO,UAAU,CAAC;IAChD,IAAI,CAAC,CAAC,UAAU,CAAC,OAAO,CAAC;QAAE,OAAO,OAAO,CAAC;IAC1C,IAAI,CAAC,CAAC,UAAU,CAAC,UAAU,CAAC;QAAE,OAAO,UAAU,CAAC;IAChD,OAAO,YAAY,CAAC;AACtB,CAAC;AAED,IAAI,MAAM,GAAmB,IAAI,CAAC;AAElC,SAAS,SAAS;IAChB,IAAI,MAAM;QAAE,OAAO,MAAM,CAAC;IAC1B,MAAM,GAAG,GAAG,OAAO,CAAC,GAAG,CAAC,eAAe,CAAC;IACxC,IAAI,CAAC,GAAG;QAAE,OAAO,IAAI,CAAC;IACtB,MAAM,GAAG,IAAI,OAAO,CAAC,GAAG,EAAE;QACxB,IAAI,EAAE,0BAA0B;QAChC,OAAO,EAAE,CAAC;QACV,aAAa,EAAE,KAAK;KACrB,CAAC,CAAC;IACH,OAAO,MAAM,CAAC;AAChB,CAAC;AAED,MAAM,UAAU,UAAU,CACxB,KAAa,EACb,aAAsC,EAAE,EACxC,SAAkB;IAElB,MAAM,EAAE,GAAG,SAAS,EAAE,CAAC;IACvB,IAAI,CAAC,EAAE;QAAE,OAAO;IAEhB,EAAE,CAAC,OAAO,CAAC;QACT,UAAU,EAAE,SAAS,IAAI,WAAW;QACpC,KAAK;QACL,UAAU,EAAE;YACV,cAAc,EAAE,OAAO,CAAC,GAAG,CAAC,mBAAmB,IAAI,SAAS;YAC5D,GAAG,UAAU;SACd;KACF,CAAC,CAAC;AACL,CAAC;AAED;;;;;;;;;;;;;;;;;;;;;GAqBG;AACH,MAAM,UAAU,iBAAiB,CAAC,GAAY;IAK5C,IAAI,GAAG,YAAY,KAAK,EAAE,CAAC;QACzB,MAAM,IAAI,GAAG,GAAG,CAAC,OAAO,IAAI,EAAE,CAAC;QAC/B,OAAO;YACL,WAAW,EAAE,GAAG,CAAC,WAAW,EAAE,IAAI,IAAI,OAAO;YAC7C,aAAa,EAAE,IAAI;YACnB,iBAAiB,EAAE,IAAI,CAAC,KAAK,CAAC,CAAC,EAAE,GAAG,CAAC;SACtC,CAAC;IACJ,CAAC;IACD,IAAI,OAAe,CAAC;IACpB,IAAI,CAAC;QACH,OAAO,GAAG,GAAG,KAAK,IAAI,CAAC,CAAC,CAAC,MAAM,CAAC,CAAC,CAAC,MAAM,CAAC,GAAG,CAAC,CAAC;IAChD,CAAC;IAAC,MAAM,CAAC;QACP,OAAO,GAAG,mBAAmB,CAAC;IAChC,CAAC;IACD,OAAO;QACL,WAAW,EAAE,SAAS;QACtB,aAAa,EAAE,OAAO;QACtB,iBAAiB,EAAE,OAAO,CAAC,KAAK,CAAC,CAAC,EAAE,GAAG,CAAC;KACzC,CAAC;AACJ,CAAC;AAED,MAAM,UAAU,aAAa,CAC3B,QAAgB,EAChB,UAAkB,EAClB,MAAsB,EACtB,SAAkB,EAClB,aAAsC,EAAE;IAExC,UAAU,CACR,WAAW,EACX;QACE,SAAS,EAAE,QAAQ;QACnB,WAAW,EAAE,UAAU;QACvB,MAAM;QACN,GAAG,UAAU;KACd,EACD,SAAS,CACV,CAAC;AACJ,CAAC;AAED,MAAM,UAAU,YAAY,CAC1B,KAAsC,EACtC,SAAiB,EACjB,aAAsC,EAAE;IAExC,UAAU,CAAC,KAAK,EAAE,UAAU,EAAE,SAAS,CAAC,CAAC;AAC3C,CAAC;AAED,MAAM,CAAC,KAAK,UAAU,iBAAiB;IACrC,IAAI,MAAM,EAAE,CAAC;QACX,MAAM,MAAM,CAAC,QAAQ,EAAE,CAAC;QACxB,MAAM,GAAG,IAAI,CAAC;IAChB,CAAC;AACH,CAAC"}

package/dist/data/mfnBasket.d.ts

@@ -0,0 +1,69 @@
+/**
+ * GUARD / GLOBE Most-Favored-Nation (MFN) reference basket.
+ *
+ * Source: CMS proposed payment models (GUARD = Medicare Part D MFN,
+ * GLOBE = Medicare Part B MFN). The basket is the set of OECD countries
+ * that meet BOTH:
+ *   - PPP-adjusted GDP per capita ≥ 60% of the US
+ *   - Total GDP ≥ $400 billion
+ *
+ * Under CMS's proposed rules, the US net price for an MFN-eligible drug
+ * is bounded by the minimum net price observed across this basket.
+ *
+ * The list below is reproduced from CMS Notice of Proposed Rulemaking
+ * (effective dates per the v1.11.0 design log #27). The criteria are
+ * public; if CMS changes the threshold, bump MFN_BASKET_REVISION below.
+ *
+ * 19 countries total — never assume "country X is in the basket" without
+ * checking against this constant.
+ */
+/** ISO 3166-1 alpha-2 country codes used as basket keys throughout. */
+export type CountryIso2 = "AT" | "BE" | "CZ" | "DK" | "FR" | "DE" | "IE" | "IT" | "NL" | "NO" | "ES" | "SE" | "CH" | "GB" | "AU" | "JP" | "KR" | "CA" | "IL";
+/**
+ * Bump this string whenever CMS revises the basket criteria or country
+ * list. Caller-facing tools should stamp this on every emitted dossier
+ * section so a 2027 reader can tell which CMS rule version applied.
+ */
+export declare const MFN_BASKET_REVISION = "2026-03";
+/**
+ * Verbatim 19-country GUARD/GLOBE basket. Order matches the CMS
+ * publication groupings (Europe → Asia-Pacific → North America → other).
+ */
+export declare const MFN_BASKET_2026: readonly CountryIso2[];
+/** Country display names — used in dossier-section rendering. */
+export declare const MFN_COUNTRY_NAMES: Readonly<Record<CountryIso2, string>>;
+/**
+ * Returns the reference set of countries for MFN ceiling computation,
+ * with optional exclusions. Caller might exclude e.g. countries with no
+ * marketed product, or override the basket for sensitivity analysis.
+ *
+ * Default = the full 19-country basket. Excluding any country shrinks
+ * the basket; the function never adds countries beyond MFN_BASKET_2026.
+ */
+export declare function getMfnReferenceCountries(opts?: {
+    excluded_countries?: readonly CountryIso2[];
+}): readonly CountryIso2[];
+/**
+ * Computes the projected MFN ceiling from a partial price map.
+ *
+ * Per CMS GUARD/GLOBE rules, the ceiling is the minimum net price in
+ * the reference basket EXCLUDING the US (which is the market being
+ * priced). If the caller supplies basket prices including a US entry,
+ * we strip it before taking the min.
+ *
+ * Returns null when no basket prices were supplied — the caller can
+ * then render "Insufficient basket data" rather than fabricating a
+ * ceiling from zero datapoints.
+ *
+ * Negative or non-finite prices are rejected (TypeError) — pricing data
+ * with bad sign would silently lower the ceiling and mislead a payer
+ * discussion.
+ */
+export declare function computeMfnCeiling(basket_prices: Partial<Record<CountryIso2, number>>, opts?: {
+    excluded_countries?: readonly CountryIso2[];
+}): {
+    ceiling: number | null;
+    contributing_countries: CountryIso2[];
+    missing_countries: CountryIso2[];
+};
+//# sourceMappingURL=mfnBasket.d.ts.map

package/dist/data/mfnBasket.d.ts.map

@@ -0,0 +1 @@
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package/dist/data/mfnBasket.js

@@ -0,0 +1,130 @@
+/**
+ * GUARD / GLOBE Most-Favored-Nation (MFN) reference basket.
+ *
+ * Source: CMS proposed payment models (GUARD = Medicare Part D MFN,
+ * GLOBE = Medicare Part B MFN). The basket is the set of OECD countries
+ * that meet BOTH:
+ *   - PPP-adjusted GDP per capita ≥ 60% of the US
+ *   - Total GDP ≥ $400 billion
+ *
+ * Under CMS's proposed rules, the US net price for an MFN-eligible drug
+ * is bounded by the minimum net price observed across this basket.
+ *
+ * The list below is reproduced from CMS Notice of Proposed Rulemaking
+ * (effective dates per the v1.11.0 design log #27). The criteria are
+ * public; if CMS changes the threshold, bump MFN_BASKET_REVISION below.
+ *
+ * 19 countries total — never assume "country X is in the basket" without
+ * checking against this constant.
+ */
+/**
+ * Bump this string whenever CMS revises the basket criteria or country
+ * list. Caller-facing tools should stamp this on every emitted dossier
+ * section so a 2027 reader can tell which CMS rule version applied.
+ */
+export const MFN_BASKET_REVISION = "2026-03";
+/**
+ * Verbatim 19-country GUARD/GLOBE basket. Order matches the CMS
+ * publication groupings (Europe → Asia-Pacific → North America → other).
+ */
+export const MFN_BASKET_2026 = [
+    // Europe (14)
+    "AT",
+    "BE",
+    "CZ",
+    "DK",
+    "FR",
+    "DE",
+    "IE",
+    "IT",
+    "NL",
+    "NO",
+    "ES",
+    "SE",
+    "CH",
+    "GB",
+    // Asia-Pacific (3)
+    "AU",
+    "JP",
+    "KR",
+    // North America (1)
+    "CA",
+    // Other OECD (1)
+    "IL",
+];
+/** Country display names — used in dossier-section rendering. */
+export const MFN_COUNTRY_NAMES = {
+    AT: "Austria",
+    BE: "Belgium",
+    CZ: "Czechia",
+    DK: "Denmark",
+    FR: "France",
+    DE: "Germany",
+    IE: "Ireland",
+    IT: "Italy",
+    NL: "Netherlands",
+    NO: "Norway",
+    ES: "Spain",
+    SE: "Sweden",
+    CH: "Switzerland",
+    GB: "United Kingdom",
+    AU: "Australia",
+    JP: "Japan",
+    KR: "South Korea",
+    CA: "Canada",
+    IL: "Israel",
+};
+/**
+ * Returns the reference set of countries for MFN ceiling computation,
+ * with optional exclusions. Caller might exclude e.g. countries with no
+ * marketed product, or override the basket for sensitivity analysis.
+ *
+ * Default = the full 19-country basket. Excluding any country shrinks
+ * the basket; the function never adds countries beyond MFN_BASKET_2026.
+ */
+export function getMfnReferenceCountries(opts) {
+    const excluded = new Set(opts?.excluded_countries ?? []);
+    return MFN_BASKET_2026.filter((c) => !excluded.has(c));
+}
+/**
+ * Computes the projected MFN ceiling from a partial price map.
+ *
+ * Per CMS GUARD/GLOBE rules, the ceiling is the minimum net price in
+ * the reference basket EXCLUDING the US (which is the market being
+ * priced). If the caller supplies basket prices including a US entry,
+ * we strip it before taking the min.
+ *
+ * Returns null when no basket prices were supplied — the caller can
+ * then render "Insufficient basket data" rather than fabricating a
+ * ceiling from zero datapoints.
+ *
+ * Negative or non-finite prices are rejected (TypeError) — pricing data
+ * with bad sign would silently lower the ceiling and mislead a payer
+ * discussion.
+ */
+export function computeMfnCeiling(basket_prices, opts) {
+    const reference = getMfnReferenceCountries(opts);
+    const contributing = [];
+    const missing = [];
+    let min = null;
+    for (const c of reference) {
+        const price = basket_prices[c];
+        if (price === undefined || price === null) {
+            missing.push(c);
+            continue;
+        }
+        if (!Number.isFinite(price) || price < 0) {
+            throw new TypeError(`computeMfnCeiling: basket price for ${c} must be a non-negative finite number, got ${String(price)}`);
+        }
+        contributing.push(c);
+        if (min === null || price < min) {
+            min = price;
+        }
+    }
+    return {
+        ceiling: contributing.length > 0 ? min : null,
+        contributing_countries: contributing,
+        missing_countries: missing,
+    };
+}
+//# sourceMappingURL=mfnBasket.js.map

package/dist/data/mfnBasket.js.map

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package/dist/models/mfnSensitivity.d.ts

@@ -0,0 +1,81 @@
+/**
+ * MFN price-sensitivity sweep for the cost-effectiveness model (design log #27).
+ *
+ * Given a basket-driven MFN ceiling and the drug's current US net price,
+ * sweep the price across that range at N discrete points and report the
+ * ICER at each. Cheaper alternative to a full PSA re-run — produces a
+ * curve users can read directly: "at the MFN ceiling, ICER drops to $X;
+ * the WTP crossover happens at price $Y."
+ *
+ * Why a deterministic sweep rather than another Monte Carlo CEAC?
+ *
+ *   - The MFN scenario is an exogenous price shock, not statistical
+ *     uncertainty. Treating it as a CEAC over a uniform distribution
+ *     conflates two distinct questions.
+ *   - A 11-point sweep is ~11 model runs vs PSA's 1000+. Ships fast.
+ *   - The output (ICER per price point + crossover price) is more
+ *     payer-readable than another CEAC slide.
+ *
+ * If a true MFN-stressed PSA is needed later, this module stays — it's
+ * the deterministic complement.
+ */
+import type { CEModelParams } from "../providers/types.js";
+export type CEModelInputs = CEModelParams;
+export interface MfnSensitivityInputs {
+    /** Lower bound of the price sweep — typically min(basket excluding US). */
+    min_basket: number;
+    /** Upper bound — typically the drug's current US net price. */
+    current_us_price: number;
+    /** Number of price points to sweep (default 11 → step every 10% of range). */
+    n_points?: number;
+    /**
+     * Willingness-to-pay threshold(s) for crossover detection. When the
+     * ICER curve crosses any of these as price falls, we record the
+     * approximate crossover price. Defaults match the WTP catalog used
+     * elsewhere in this module: NHS £30K, US $100K, US $150K.
+     */
+    wtp_thresholds?: number[];
+}
+export interface MfnSensitivityPoint {
+    drug_price: number;
+    /** ICER at this price; Infinity when delta_qaly <= 0. */
+    icer: number;
+}
+export interface MfnCrossover {
+    wtp: number;
+    /**
+     * Approximate price where ICER = wtp. Null when the ICER never
+     * crosses the threshold over the sweep range (cost-effective at
+     * every point, or cost-INeffective at every point).
+     */
+    crossover_price: number | null;
+}
+export interface MfnSensitivityResult {
+    /** Echoes inputs so the caller can stamp the output for audit. */
+    range: {
+        min_basket: number;
+        current_us_price: number;
+        n_points: number;
+    };
+    /** ICER per price point, ordered low-price → high-price. */
+    curve: MfnSensitivityPoint[];
+    /** Crossover prices per WTP threshold (linear interpolation between points). */
+    crossovers: MfnCrossover[];
+    /** ICER at the MFN ceiling itself (min_basket); first point in `curve`. */
+    icer_at_ceiling: number;
+    /** ICER at the unstressed US price; last point in `curve`. */
+    icer_at_current: number;
+}
+/**
+ * Run the price sweep. The caller injects a `runModel` callback so this
+ * module stays decoupled from the Markov / PartSA implementations and
+ * is trivially mockable in tests.
+ *
+ * Returns sorted by ascending price. Crossover prices use linear
+ * interpolation between adjacent points — accurate enough for the
+ * payer-conversation purpose; not a root-finding bisection.
+ */
+export declare function runMfnSensitivity(baseParams: CEModelInputs, inputs: MfnSensitivityInputs, runModel: (params: CEModelInputs) => {
+    icer: number;
+}): MfnSensitivityResult;
+//# sourceMappingURL=mfnSensitivity.d.ts.map

package/dist/models/mfnSensitivity.d.ts.map

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package/dist/models/mfnSensitivity.js

@@ -0,0 +1,104 @@
+/**
+ * MFN price-sensitivity sweep for the cost-effectiveness model (design log #27).
+ *
+ * Given a basket-driven MFN ceiling and the drug's current US net price,
+ * sweep the price across that range at N discrete points and report the
+ * ICER at each. Cheaper alternative to a full PSA re-run — produces a
+ * curve users can read directly: "at the MFN ceiling, ICER drops to $X;
+ * the WTP crossover happens at price $Y."
+ *
+ * Why a deterministic sweep rather than another Monte Carlo CEAC?
+ *
+ *   - The MFN scenario is an exogenous price shock, not statistical
+ *     uncertainty. Treating it as a CEAC over a uniform distribution
+ *     conflates two distinct questions.
+ *   - A 11-point sweep is ~11 model runs vs PSA's 1000+. Ships fast.
+ *   - The output (ICER per price point + crossover price) is more
+ *     payer-readable than another CEAC slide.
+ *
+ * If a true MFN-stressed PSA is needed later, this module stays — it's
+ * the deterministic complement.
+ */
+const DEFAULT_WTP = [30000, 100000, 150000];
+/**
+ * Run the price sweep. The caller injects a `runModel` callback so this
+ * module stays decoupled from the Markov / PartSA implementations and
+ * is trivially mockable in tests.
+ *
+ * Returns sorted by ascending price. Crossover prices use linear
+ * interpolation between adjacent points — accurate enough for the
+ * payer-conversation purpose; not a root-finding bisection.
+ */
+export function runMfnSensitivity(baseParams, inputs, runModel) {
+    const n = Math.max(2, inputs.n_points ?? 11);
+    if (!Number.isFinite(inputs.min_basket) || !Number.isFinite(inputs.current_us_price)) {
+        throw new TypeError("runMfnSensitivity: min_basket and current_us_price must be finite numbers");
+    }
+    if (inputs.min_basket < 0 || inputs.current_us_price < 0) {
+        throw new TypeError("runMfnSensitivity: prices must be non-negative");
+    }
+    if (inputs.min_basket > inputs.current_us_price) {
+        throw new TypeError(`runMfnSensitivity: min_basket (${inputs.min_basket}) must be <= current_us_price (${inputs.current_us_price})`);
+    }
+    const step = (inputs.current_us_price - inputs.min_basket) / (n - 1);
+    const curve = [];
+    for (let i = 0; i < n; i++) {
+        const price = inputs.min_basket + step * i;
+        const perturbed = {
+            ...baseParams,
+            cost_inputs: {
+                ...baseParams.cost_inputs,
+                drug_cost_annual: price,
+            },
+        };
+        const { icer } = runModel(perturbed);
+        curve.push({ drug_price: price, icer });
+    }
+    const thresholds = inputs.wtp_thresholds ?? DEFAULT_WTP;
+    const crossovers = thresholds.map((wtp) => ({
+        wtp,
+        crossover_price: findCrossover(curve, wtp),
+    }));
+    return {
+        range: {
+            min_basket: inputs.min_basket,
+            current_us_price: inputs.current_us_price,
+            n_points: n,
+        },
+        curve,
+        crossovers,
+        icer_at_ceiling: curve[0].icer,
+        icer_at_current: curve[curve.length - 1].icer,
+    };
+}
+/**
+ * Find the price at which the ICER curve crosses `wtp` using linear
+ * interpolation between adjacent points. Returns null when the curve
+ * doesn't cross — either ICER stays below wtp everywhere (cost-effective
+ * at every price in range) or stays above (cost-INeffective everywhere).
+ *
+ * Infinity ICERs (delta_qaly <= 0) are treated as "doesn't cross" rather
+ * than collapsing the interpolation — a degenerate iteration shouldn't
+ * fabricate a crossover.
+ */
+function findCrossover(curve, wtp) {
+    for (let i = 0; i < curve.length - 1; i++) {
+        const a = curve[i];
+        const b = curve[i + 1];
+        if (!Number.isFinite(a.icer) || !Number.isFinite(b.icer))
+            continue;
+        const aDelta = a.icer - wtp;
+        const bDelta = b.icer - wtp;
+        if (aDelta === 0)
+            return a.drug_price;
+        if (bDelta === 0)
+            return b.drug_price;
+        if (aDelta * bDelta < 0) {
+            // Sign change between a and b → interpolate.
+            const t = aDelta / (aDelta - bDelta);
+            return a.drug_price + t * (b.drug_price - a.drug_price);
+        }
+    }
+    return null;
+}
+//# sourceMappingURL=mfnSensitivity.js.map

package/dist/models/mfnSensitivity.js.map

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package/dist/providers/types.d.ts

@@ -79,6 +79,12 @@ export interface CEModelParams {
         survival_distribution?: "exponential" | "weibull";
         weibull_shape?: number;
     };
+    mfn_sensitivity?: {
+        min_basket: number;
+        current_us_price: number;
+        n_points?: number;
+        wtp_thresholds?: number[];
+    };
 }
 export interface PicoDefinition {
     id: string;
@@ -126,6 +132,13 @@ export interface DossierParams {
     unmet_need_summary?: string;
     /** Design log #26: array of RegulatoryStatusResult objects from hta_workflow Phase 3.6. Renders "Regulatory Landscape" section for nice/jca/gvd/amcp. */
     regulatory_landscape?: any[];
+    /** Design log #27: MFN (Most-Favored-Nation) pricing context. Auto-renders MFN Exposure section for hta_body="amcp"; opt-in for other bodies via basket_prices presence. Basket = 19-country CMS GUARD/GLOBE OECD set (src/data/mfnBasket.ts). */
+    mfn_context?: {
+        basket_prices?: Record<string, number>;
+        us_current_net_price?: number;
+        basket_revision?: string;
+        excluded_countries?: string[];
+    };
 }
 export interface ToolResult {
     content: string | object;
@@ -184,6 +197,24 @@ export interface CEModelResult {
     };
     psa?: PSASummary;
     owsa?: OWSASummary[];
+    /** Design log #27: MFN price-sensitivity sweep result. Present when caller supplied mfn_sensitivity. */
+    mfn_sensitivity?: {
+        range: {
+            min_basket: number;
+            current_us_price: number;
+            n_points: number;
+        };
+        curve: Array<{
+            drug_price: number;
+            icer: number;
+        }>;
+        crossovers: Array<{
+            wtp: number;
+            crossover_price: number | null;
+        }>;
+        icer_at_ceiling: number;
+        icer_at_current: number;
+    };
     wtp_analysis: {
         nhs: WTPAssessment;
         us_payer: WTPAssessment;

package/dist/providers/types.d.ts.map

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