heor-agent-mcp 1.0.3 → 1.0.4

package/README.md

@@ -12,6 +12,21 @@ Built for pharmaceutical, biotech, CRO, and medical affairs teams who need rigor
 
 ---
 
+## What's new in v1.0.4
+
+Senior HEOR methodology + ChatGPT support:
+
+- **GRADE inconsistency now uses I²** instead of study count. Single-study comparisons return `not_assessable` (per Cochrane 10.10) instead of being silently auto-downgraded as "Serious". Pass `heterogeneity_per_outcome` to `hta_dossier` and the Cochrane bands (50–74% Moderate, 75–89% Serious, ≥90% Very Serious) are applied directly.
+- **GRADE upgrading (Guyatt 2011)** — observational evidence with strong effects can now be upgraded from Low. Three criteria via `upgrading_per_outcome`: large effect (RR <0.5/>2.0 → +1; <0.2/>5.0 → +2), dose-response (+1), plausible confounding biasing toward null (+1). Capped at +2.
+- **Bucher consistency check** — when direct head-to-head A-vs-C evidence exists alongside the indirect A-vs-C estimate, `evidence_indirect` automatically tests Bucher's consistency assumption and flags violations (NICE DSU TSD 18). |z|≥1.96 = "substantial — consistency assumption appears violated."
+- **EQ-5D 5L impact is baseline-utility-aware.** Biz 2026 reports category-level medians, but the new 5L value set compresses utilities in the 0.6–0.9 range — a drug for mild plaque psoriasis (baseline ~0.85) sees a much bigger ICER increase than one for severe HS (baseline ~0.45), even though both are `non_cancer_qol_only`. Pass `baseline_utility` to `utility_value_set` for a calibrated estimate.
+- **ChatGPT Custom GPT support** — new OpenAPI 3.1 adapter at `/api/openapi` lets you build a Custom GPT in 5 minutes. See [ChatGPT Custom GPT](#chatgpt-custom-gpt) below.
+- **Surface-tagged analytics** — every `tool_call` PostHog event now carries a `surface` property (`claude_anthropic_web` / `chatgpt_adapter` / `claude_desktop` / `direct_mcp`) so you can break down usage by client.
+
+See [CHANGELOG.md](./CHANGELOG.md) for the full diff.
+
+---
+
 ## Quick Start
 
 ### Claude Code
@@ -45,15 +60,23 @@ Add to your MCP configuration:
 
 ---
 
-## Tools
+## Tools (17)
 
 | Tool | Purpose |
 |------|---------|
-| `literature_search` | Search 42 data sources with a full PRISMA-style audit trail |
+| `literature_search` | Search 44 data sources with a full PRISMA-style audit trail |
 | `screen_abstracts` | PICO-based relevance scoring and study design classification |
 | `risk_of_bias` | Cochrane RoB 2 / ROBINS-I / AMSTAR-2 with GRADE RoB domain summary |
-| `cost_effectiveness_model` | Markov / PartSA / decision-tree CEA with PSA, OWSA, CEAC, EVPI |
-| `hta_dossier_prep` | Draft submissions for NICE, EMA, FDA, IQWiG, HAS, and EU JCA — GRADE table uses structured RoB when `rob_results` passed |
+| `evidence_network` | Build treatment comparison network and assess NMA feasibility |
+| `evidence_indirect` | Bucher and frequentist NMA with **automatic consistency check** vs direct h2h evidence (NICE DSU TSD 18) |
+| `population_adjusted_comparison` | MAIC and STC for population-adjusted indirect comparisons |
+| `survival_fitting` | Fit 5 parametric distributions to KM data (NICE DSU TSD 14) |
+| `itc_feasibility` | Assess the 3-assumption ITC framework and recommend Bucher / NMA / MAIC / STC / ML-NMR |
+| `cost_effectiveness_model` | Markov / PartSA / decision-tree CEA with PSA, OWSA, CEAC, EVPI, EVPPI; QALY + evLYG support |
+| `budget_impact_model` | ISPOR-compliant BIA with year-by-year output and treatment-displacement modelling |
+| `hta_dossier` | Draft submissions for NICE, EMA, FDA, IQWiG, HAS, and EU JCA — GRADE table uses structured RoB when `rob_results` passed; **inconsistency uses I² when `heterogeneity_per_outcome` passed**; **GRADE upgrading (Guyatt 2011) supported via `upgrading_per_outcome`** |
+| `utility_value_set` | EQ-5D-3L / 5L value-set reference + **baseline-utility-aware** Biz 2026 ICER impact estimator (UK 5L transition) |
+| `validate_links` | HTTP validation of citation URLs before presentation |
 | `project_create` | Initialize a persistent project workspace |
 | `knowledge_search` | Full-text search across a project's raw/ and wiki/ trees |
 | `knowledge_read` | Read any file from a project's knowledge base |
@@ -61,7 +84,7 @@ Add to your MCP configuration:
 
 ### `literature_search`
 
-Searches across 42 sources in parallel. Every call returns a **source selection table** showing which of the 42 sources were used and why — essential for HTA audit trails.
+Searches across 44 sources in parallel. Every call returns a **source selection table** showing which of the 44 sources were used and why — essential for HTA audit trails.
 
 **Example call:**
 ```json
@@ -197,7 +220,7 @@ This single prompt exercises: `project_create` → `literature_search` → `scre
 
 ## Data Sources
 
-**42 sources across 9 categories.** Every `literature_search` call includes a source selection table showing used/not-used status and reason for each.
+**44 sources across 10 categories.** Every `literature_search` call includes a source selection table showing used/not-used status and reason for each.
 
 <details>
 <summary><b>Biomedical & Clinical Trials (5)</b></summary>
@@ -270,9 +293,11 @@ This single prompt exercises: `project_create` → `literature_search` → `scre
 </details>
 
 <details>
-<summary><b>Other (1)</b></summary>
+<summary><b>HEOR Methodology & Utility Reference (3)</b></summary>
 
 - **ISPOR** — HEOR methodology and conference abstracts
+- **OHE (Office of Health Economics)** — EQ-5D value set research and HEOR methodology
+- **EuroQol Group** — EQ-5D instruments, value sets, and registry
 </details>
 
 ---
@@ -293,7 +318,7 @@ DOCX files are saved to `~/.heor-agent/projects/{project}/reports/` (when a proj
 
 Every tool call returns a full audit record:
 
-- **Source selection table** — all 42 sources with used/not-used and reason
+- **Source selection table** — all 44 sources with used/not-used and reason
 - **Sources queried** — queries sent, response counts, status, latency
 - **Inclusions / exclusions** — counts with reasons
 - **Methodology** — PRISMA-style for literature, ISPOR/NICE for economics
@@ -333,10 +358,11 @@ A companion chat interface is available at:
 
 **https://web-michael-ns-projects.vercel.app**
 
-- Chat with Claude Opus 4.6 + all 7 HEOR tools
+- Chat with Claude Sonnet 4.6 + all 17 HEOR tools
 - **BYOK (Bring Your Own Key)** — paste your Anthropic API key in the settings; it stays in your browser's localStorage and is never stored on our servers
-- Markdown rendering with styled tables, tool call cards with live progress timers
-- Example prompts for common HEOR workflows
+- Markdown rendering with styled tables, tool call cards with live progress timers, and theme-aware mermaid network diagrams
+- 12 example prompts covering literature search, CEA, BIA, NMA, ITC feasibility, RoB, EQ-5D 5L, EU JCA dossiers
+- Per-request MCP sessions (no cross-user session bleed)
 
 The web UI calls the hosted MCP server on Railway for tool execution. No setup required — just add your API key and start querying.
 
@@ -353,6 +379,70 @@ Set `MCP_SERVER_URL` to point to your own MCP server instance (default: the publ
 
 ---
 
+## ChatGPT Custom GPT
+
+HEORAgent can also be used as a ChatGPT Custom GPT Action — useful when you (or your team) prefer the ChatGPT interface or have a ChatGPT Plus/Team account but no Anthropic API access.
+
+The web tier exposes an OpenAPI 3.1 adapter at `/api/openapi`, with one POST endpoint per tool at `/api/v1/{tool_name}`. ChatGPT speaks this contract natively.
+
+### What's different from the Anthropic surface
+
+| | Web UI / MCP / Claude Desktop | ChatGPT Custom GPT |
+|---|---|---|
+| Streaming | yes (SSE) | no (45s single response) |
+| `psa_iterations` | up to 10,000 | capped to 1,000 (CEA) / 500 (BIA) |
+| `literature_search.runs` | 1–5 | capped to 1 |
+| `literature_search.max_results` | up to 100 | capped to 30 |
+| Auth model | BYOK Anthropic | optional `X-API-Key` header (server-side `CHATGPT_ADAPTER_TOKEN`) |
+| Surface label in PostHog | `claude_anthropic_web` / `claude_desktop` | `chatgpt_adapter` |
+
+The caps exist because ChatGPT Actions hard-fail at the 45-second response timeout. PSA, multi-run literature search, and full max_results would routinely exceed it. The web UI and MCP clients are unaffected.
+
+### Build a Custom GPT (ChatGPT Plus / Team required)
+
+1. Visit [chatgpt.com/gpts/editor](https://chatgpt.com/gpts/editor) and click **Create**.
+2. **Configure** tab — fill in name (e.g., "HEORAgent"), description, and conversation starters. Paste the system prompt from `web/lib/claude.ts` (or write your own — the tool descriptions are self-documenting).
+3. **Actions** → **Create new action** → **Import from URL** → paste:
+   ```
+   https://web-michael-ns-projects.vercel.app/api/openapi
+   ```
+   ChatGPT auto-imports all 17 endpoints with their schemas.
+4. **Authentication** — choose **None** for the open public endpoint, or **API Key** with the `CHATGPT_ADAPTER_TOKEN` value if you've configured one (recommended for prod).
+5. **Privacy policy URL** — required by GPT Store. Use the web UI's privacy URL or your own.
+6. **Test** in the playground (right pane), then **Publish** → "Anyone with the link" or "GPT Store".
+
+### Securing the adapter for production
+
+By default the `/api/v1/*` endpoint is open. Two layers of protection are recommended for any public-facing GPT:
+
+```bash
+# 1. Token-gate the endpoint
+cd web
+vercel env add CHATGPT_ADAPTER_TOKEN production   # generate a long random token
+# Configure the same token in your Custom GPT under Authentication → API Key
+
+# 2. Built-in rate limit
+# 60 req/min per IP is enforced automatically (lib/rateLimit.ts).
+# For multi-region/high-traffic prod, swap in @upstash/ratelimit + Vercel KV.
+```
+
+### Sample call (manual, no GPT needed)
+
+```bash
+curl -X POST https://web-michael-ns-projects.vercel.app/api/v1/utility_value_set \
+  -H "Content-Type: application/json" \
+  -d '{
+        "action": "estimate_impact",
+        "indication_type": "non_cancer_qol_only",
+        "baseline_utility": 0.85,
+        "base_icer": 30000
+      }'
+```
+
+Returns the Biz 2026 baseline-utility-adjusted ICER projection (the new EQ-5D 5L impact estimator).
+
+---
+
 ## HTTP Transport
 
 The server supports both **stdio** (default, for local MCP clients) and **Streamable HTTP** (for hosted deployment).
@@ -379,7 +469,7 @@ HTTP endpoints:
 git clone https://github.com/neptun2000/heor-agent-mcp
 cd heor-agent-mcp
 npm install
-npm test          # 244 tests across 66 suites
+npm test          # 401 tests across 84 suites
 npm run build     # Compile TypeScript to dist/
 npm run dev       # Run with tsx (no build step)
 ```
@@ -398,10 +488,10 @@ npm run dev       # Run with tsx (no build step)
 ┌────────────────▼──────────────────────────┐
 │  heor-agent-mcp server                    │
 │  ┌──────────────────────────────────────┐ │
-│  │ 7 MCP tools (Zod-validated)          │ │
+│  │ 17 MCP tools (Zod-validated)         │ │
 │  ├──────────────────────────────────────┤ │
 │  │ DirectProvider (default)             │ │
-│  │   ├─ 42 source fetchers              │ │
+│  │   ├─ 44 source fetchers              │ │
 │  │   ├─ Audit builder + PRISMA trail    │ │
 │  │   ├─ Markov / PartSA economic models │ │
 │  │   ├─ Markdown + DOCX formatters      │ │

package/dist/analytics.d.ts

@@ -1,3 +1,12 @@
+/**
+ * Map MCP `clientInfo.name` (set by the calling client during initialize)
+ * to a canonical surface label so PostHog can distinguish events from
+ * Claude Desktop, the Vercel web UI, the ChatGPT Custom GPT adapter, etc.
+ *
+ * Returns "direct_mcp" for unknown / npx / third-party clients.
+ */
+export type ClientSurface = "claude_anthropic_web" | "chatgpt_adapter" | "claude_desktop" | "smithery" | "glama" | "pulsemcp" | "direct_mcp";
+export declare function inferSurface(clientName: string | undefined): ClientSurface;
 export declare function trackEvent(event: string, properties?: Record<string, unknown>, sessionId?: string): void;
 export declare function trackToolCall(toolName: string, durationMs: number, status: "ok" | "error", sessionId?: string, properties?: Record<string, unknown>): void;
 export declare function trackSession(event: "session_start" | "session_end", sessionId: string, properties?: Record<string, unknown>): void;

package/dist/analytics.d.ts.map

@@ -1 +1 @@
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package/dist/analytics.js

@@ -1,4 +1,24 @@
 import { PostHog } from "posthog-node";
+export function inferSurface(clientName) {
+    if (!clientName)
+        return "direct_mcp";
+    const n = clientName.toLowerCase();
+    if (n.startsWith("heor-web-ui"))
+        return "claude_anthropic_web";
+    if (n.startsWith("chatgpt-adapter"))
+        return "chatgpt_adapter";
+    if (n === "claude" ||
+        n.startsWith("claude-ai") ||
+        n.startsWith("claude-desktop"))
+        return "claude_desktop";
+    if (n.startsWith("smithery"))
+        return "smithery";
+    if (n.startsWith("glama"))
+        return "glama";
+    if (n.startsWith("pulsemcp"))
+        return "pulsemcp";
+    return "direct_mcp";
+}
 let client = null;
 function getClient() {
     if (client)

package/dist/analytics.js.map

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package/dist/grade/eq5dImpact.d.ts.map

@@ -1 +1 @@
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package/dist/grade/eq5dImpact.js

@@ -59,7 +59,20 @@ export function estimateBaselineAdjustedImpact(indication, baseline_utility) {
         }
     }
     const published = getImpactEstimate(indication);
-    const median = published?.median_icer_change_pct ?? 0;
+    // Guard: indication categories without a published median (future entries
+    // added before data is populated) must not silently return a degenerate
+    // {0, 0, 0} range. Return is_baseline_adjusted=false with an explicit
+    // "no estimate available" rationale so callers can branch.
+    if (!published) {
+        return {
+            indication_type: indication,
+            icer_change_pct: { point: 0, lower: 0, upper: 0 },
+            is_baseline_adjusted: false,
+            baseline_utility,
+            rationale: `No published impact estimate for ${indication} — this category has no Biz 2026 entry yet. Re-run your model under both value sets for a direct estimate.`,
+        };
+    }
+    const median = published.median_icer_change_pct;
     // Range for unmodulated estimate (±25% of median to reflect inter-study spread)
     const baseRange = {
         point: median,
@@ -71,7 +84,7 @@ export function estimateBaselineAdjustedImpact(indication, baseline_utility) {
             indication_type: indication,
             icer_change_pct: baseRange,
             is_baseline_adjusted: false,
-            rationale: `Published median for ${indication} (Biz et al. 2026, n=${published?.examples?.length ?? 0} indication examples).`,
+            rationale: `Published median for ${indication} (Biz et al. 2026, n=${published.examples?.length ?? 0} indication examples).`,
         };
     }
     if (indication === "non_cancer_life_extending") {
@@ -108,8 +121,8 @@ export function estimateBaselineAdjustedImpact(indication, baseline_utility) {
         indication_type: indication,
         icer_change_pct: {
             point: adjustedPoint,
-            lower: adjustedPoint - Math.abs(adjustedPoint) * 0.30,
-            upper: adjustedPoint + Math.abs(adjustedPoint) * 0.30,
+            lower: adjustedPoint - Math.abs(adjustedPoint) * 0.3,
+            upper: adjustedPoint + Math.abs(adjustedPoint) * 0.3,
         },
         is_baseline_adjusted: true,
         baseline_utility,

package/dist/grade/eq5dImpact.js.map

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package/dist/grade/inconsistency.d.ts.map

@@ -1 +1 @@
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+{"version":3,"file":"inconsistency.d.ts","sourceRoot":"","sources":["../../src/grade/inconsistency.ts"],"names":[],"mappings":"AAAA;;;;;;;;;;;;;;;;;;;;GAoBG;AAEH,MAAM,MAAM,kBAAkB,GAC1B,gBAAgB,GAChB,KAAK,GACL,UAAU,GACV,SAAS,GACT,cAAc,CAAC;AAEnB,MAAM,WAAW,uBAAuB;IACtC,KAAK,EAAE,kBAAkB,CAAC;IAC1B,eAAe,EAAE,CAAC,GAAG,CAAC,GAAG,CAAC,CAAC;IAC3B,SAAS,EAAE,MAAM,CAAC;CACnB;AAED,wBAAgB,mBAAmB,CACjC,SAAS,EAAE,MAAM,EACjB,aAAa,EAAE,MAAM,GAAG,IAAI,GAC3B,uBAAuB,CAsDzB"}

package/dist/grade/inconsistency.js

@@ -35,8 +35,12 @@ export function assessInconsistency(n_studies, i_squared_pct) {
         };
     }
     if (i_squared_pct == null) {
+        // Was: level="Moderate", downgrade_steps=0 — internally inconsistent
+        // (every other Moderate path uses 1 step). Returning not_assessable
+        // with 0 downgrade forces an explicit manual decision instead of
+        // silently inflating GRADE certainty.
         return {
-            level: "Moderate",
+            level: "not_assessable",
             downgrade_steps: 0,
             rationale: "Multiple studies but I² not computed — manual heterogeneity review recommended",
         };

package/dist/grade/inconsistency.js.map

@@ -1 +1 @@
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package/dist/network/bucher.d.ts.map

@@ -1 +1 @@
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+{"version":3,"file":"bucher.d.ts","sourceRoot":"","sources":["../../src/network/bucher.ts"],"names":[],"mappings":"AAAA,OAAO,KAAK,EACV,aAAa,EACb,cAAc,EACd,gBAAgB,EAChB,gBAAgB,EACjB,MAAM,YAAY,CAAC;AAGpB,iCAAiC;AACjC,wBAAgB,QAAQ,CAAC,KAAK,EAAE,MAAM,EAAE,KAAK,EAAE,MAAM,GAAG,MAAM,CAE7D;AAED,6DAA6D;AAC7D,wBAAgB,SAAS,CAAC,CAAC,EAAE,MAAM,GAAG,MAAM,CAc3C;AAED,sCAAsC;AACtC,wBAAgB,WAAW,CAAC,CAAC,EAAE,MAAM,GAAG,MAAM,CAE7C;AA8CD,4CAA4C;AAC5C,wBAAgB,eAAe,CAC7B,OAAO,EAAE,KAAK,CAAC;IAAE,KAAK,EAAE,MAAM,CAAC;IAAC,EAAE,EAAE,MAAM,CAAA;CAAE,CAAC,GAC5C,cAAc,CAqBhB;AAED,2DAA2D;AAC3D,wBAAgB,cAAc,CAC5B,EAAE,EAAE,cAAc,EAClB,EAAE,EAAE,cAAc,GACjB;IAAE,KAAK,EAAE,MAAM,CAAC;IAAC,EAAE,EAAE,MAAM,CAAC;IAAC,CAAC,EAAE,MAAM,CAAC;IAAC,OAAO,EAAE,MAAM,CAAA;CAAE,CAM3D;AAED;;;;;;;GAOG;AACH,wBAAgB,yBAAyB,CACvC,YAAY,EAAE,MAAM,EACpB,UAAU,EAAE,MAAM,EAClB,MAAM,EAAE,MAAM,EACd,QAAQ,EAAE,gBAAgB,EAAE,EAC5B,QAAQ,EAAE,gBAAgB,EAAE,EAC5B,OAAO,EAAE,MAAM,EACf,OAAO,EAAE,aAAa,EACtB,QAAQ,CAAC,EAAE,gBAAgB,EAAE,GAC5B,gBAAgB,CAqElB"}

package/dist/network/bucher.js

@@ -27,11 +27,12 @@ function isLogScale(measure) {
     return measure === "OR" || measure === "RR" || measure === "HR";
 }
 /** Convert to working scale (log for ratio measures) */
-function toWorkingScale(estimate, se, measure) {
-    if (isLogScale(measure)) {
-        return { value: Math.log(estimate), se };
-    }
-    return { value: estimate, se };
+// Returns the working-scale point estimate. The SE parameter was
+// previously included but acted as dead weight (passed through unchanged)
+// — that was a correctness trap because for OR/HR/RR the original-scale
+// SE is NOT the log-scale SE. Use seOnWorkingScale() for that.
+function toWorkingScale(estimate, measure) {
+    return isLogScale(measure) ? Math.log(estimate) : estimate;
 }
 /** Convert SE from CI on the original scale to working scale */
 function seOnWorkingScale(estimate, ci_lower, ci_upper, measure) {
@@ -89,13 +90,15 @@ export function bucherIndirect(ab, cb) {
  * Returns the indirect estimate of A vs C.
  */
 export function computeIndirectComparison(intervention, comparator, bridge, directAB, directCB, outcome, measure, directAC) {
-    // Convert to working scale and pool
+    // Convert to working scale and pool. The SE on the working scale (log
+    // for ratio measures) comes from seOnWorkingScale, NOT from
+    // toWorkingScale (which only transforms the point estimate).
     const abStudies = directAB.map((d) => ({
-        value: toWorkingScale(d.estimate, seOnWorkingScale(d.estimate, d.ci_lower, d.ci_upper, measure), measure).value,
+        value: toWorkingScale(d.estimate, measure),
         se: seOnWorkingScale(d.estimate, d.ci_lower, d.ci_upper, measure),
     }));
     const cbStudies = directCB.map((d) => ({
-        value: toWorkingScale(d.estimate, seOnWorkingScale(d.estimate, d.ci_lower, d.ci_upper, measure), measure).value,
+        value: toWorkingScale(d.estimate, measure),
         se: seOnWorkingScale(d.estimate, d.ci_lower, d.ci_upper, measure),
     }));
     const pooledAB = poolFixedEffect(abStudies);
@@ -110,7 +113,7 @@ export function computeIndirectComparison(intervention, comparator, bridge, dire
     let consistency_check;
     if (directAC && directAC.length > 0) {
         const acStudies = directAC.map((d) => ({
-            value: toWorkingScale(d.estimate, seOnWorkingScale(d.estimate, d.ci_lower, d.ci_upper, measure), measure).value,
+            value: toWorkingScale(d.estimate, measure),
             se: seOnWorkingScale(d.estimate, d.ci_lower, d.ci_upper, measure),
         }));
         const pooledAC = poolFixedEffect(acStudies);

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package/dist/network/consistency.d.ts

@@ -35,8 +35,15 @@ export type ConsistencySeverity = "untestable" | "none" | "moderate" | "substant
 export interface ConsistencyAssessment {
     has_conflict: boolean;
     severity: ConsistencySeverity;
+    /** direct − indirect (positive when direct exceeds indirect). Same scale as input. */
     difference: number;
+    /** Pooled SE: sqrt(SE_direct² + SE_indirect²). */
     se_difference: number;
+    /**
+     * Signed z = (direct − indirect) / SE_diff. Sign indicates which side
+     * the disagreement falls on. Severity bands use |z|, but consumers
+     * presenting the value should preserve the sign for direction.
+     */
     z_difference: number;
     rationale: string;
 }

package/dist/network/consistency.d.ts.map

@@ -1 +1 @@
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+{"version":3,"file":"consistency.d.ts","sourceRoot":"","sources":["../../src/network/consistency.ts"],"names":[],"mappings":"AAAA;;;;;;;;;;;;;;;;;;;;GAoBG;AAEH,MAAM,WAAW,gBAAgB;IAC/B,gFAAgF;IAChF,QAAQ,EAAE;QAAE,KAAK,EAAE,MAAM,CAAC;QAAC,EAAE,EAAE,MAAM,CAAA;KAAE,CAAC;IACxC,8EAA8E;IAC9E,MAAM,EAAE;QAAE,KAAK,EAAE,MAAM,CAAC;QAAC,EAAE,EAAE,MAAM,CAAA;KAAE,GAAG,IAAI,CAAC;CAC9C;AAED,MAAM,MAAM,mBAAmB,GAC3B,YAAY,GACZ,MAAM,GACN,UAAU,GACV,aAAa,CAAC;AAElB,MAAM,WAAW,qBAAqB;IACpC,YAAY,EAAE,OAAO,CAAC;IACtB,QAAQ,EAAE,mBAAmB,CAAC;IAC9B,sFAAsF;IACtF,UAAU,EAAE,MAAM,CAAC;IACnB,kDAAkD;IAClD,aAAa,EAAE,MAAM,CAAC;IACtB;;;;OAIG;IACH,YAAY,EAAE,MAAM,CAAC;IACrB,SAAS,EAAE,MAAM,CAAC;CACnB;AAED,wBAAgB,yBAAyB,CACvC,KAAK,EAAE,gBAAgB,GACtB,qBAAqB,CAuEvB"}

package/dist/network/consistency.js

@@ -31,8 +31,7 @@ export function assessConsistencyConflict(input) {
         };
     }
     const difference = input.direct.value - input.indirect.value;
-    const se_difference = Math.sqrt(input.direct.se * input.direct.se +
-        input.indirect.se * input.indirect.se);
+    const se_difference = Math.sqrt(input.direct.se * input.direct.se + input.indirect.se * input.indirect.se);
     const z = se_difference > 0 ? difference / se_difference : 0;
     const absZ = Math.abs(z);
     // Opposite-direction check: both estimates significant in opposite directions

package/dist/network/consistency.js.map

@@ -1 +1 @@
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package/dist/schemas/dossierInputSchemas.d.ts

@@ -0,0 +1,118 @@
+/**
+ * Zod schemas for inputs that htaDossierPrep accepts from upstream tools.
+ *
+ * Previously these were `z.any()` — which silently accepted garbage and let
+ * malformed shapes crash deep inside `generateGradeTable`. With proper
+ * schemas, the tool boundary rejects bad input with a field-level error
+ * message that's actionable for the caller (Claude, ChatGPT, or a human).
+ *
+ * `passthrough()` is used so unknown fields are preserved (forward-compat
+ * for adding new fields without breaking older callers).
+ */
+import { z } from "zod";
+/**
+ * Single literature search result. Accepts the canonical shape produced by
+ * literature_search; in practice many fields may be absent (e.g., user pastes
+ * a cherry-picked subset), so only title + abstract are required.
+ */
+export declare const LiteratureResultSchema: z.ZodObject<{
+    id: z.ZodOptional<z.ZodString>;
+    source: z.ZodOptional<z.ZodString>;
+    title: z.ZodString;
+    authors: z.ZodOptional<z.ZodArray<z.ZodString, "many">>;
+    date: z.ZodOptional<z.ZodString>;
+    study_type: z.ZodOptional<z.ZodString>;
+    abstract: z.ZodString;
+    url: z.ZodOptional<z.ZodString>;
+}, "passthrough", z.ZodTypeAny, z.objectOutputType<{
+    id: z.ZodOptional<z.ZodString>;
+    source: z.ZodOptional<z.ZodString>;
+    title: z.ZodString;
+    authors: z.ZodOptional<z.ZodArray<z.ZodString, "many">>;
+    date: z.ZodOptional<z.ZodString>;
+    study_type: z.ZodOptional<z.ZodString>;
+    abstract: z.ZodString;
+    url: z.ZodOptional<z.ZodString>;
+}, z.ZodTypeAny, "passthrough">, z.objectInputType<{
+    id: z.ZodOptional<z.ZodString>;
+    source: z.ZodOptional<z.ZodString>;
+    title: z.ZodString;
+    authors: z.ZodOptional<z.ZodArray<z.ZodString, "many">>;
+    date: z.ZodOptional<z.ZodString>;
+    study_type: z.ZodOptional<z.ZodString>;
+    abstract: z.ZodString;
+    url: z.ZodOptional<z.ZodString>;
+}, z.ZodTypeAny, "passthrough">>;
+export type LiteratureResultInput = z.infer<typeof LiteratureResultSchema>;
+/**
+ * Output of the risk_of_bias tool, intended to be passed back into
+ * hta_dossier so the GRADE table uses structured RoB judgments instead of
+ * the heuristic fallback.
+ */
+export declare const RobResultsSchema: z.ZodObject<{
+    summary: z.ZodObject<{
+        rob_judgment: z.ZodString;
+        downgrade: z.ZodBoolean;
+        rationale: z.ZodString;
+    }, "passthrough", z.ZodTypeAny, z.objectOutputType<{
+        rob_judgment: z.ZodString;
+        downgrade: z.ZodBoolean;
+        rationale: z.ZodString;
+    }, z.ZodTypeAny, "passthrough">, z.objectInputType<{
+        rob_judgment: z.ZodString;
+        downgrade: z.ZodBoolean;
+        rationale: z.ZodString;
+    }, z.ZodTypeAny, "passthrough">>;
+    overall_certainty_start: z.ZodEnum<["High", "Low"]>;
+}, "passthrough", z.ZodTypeAny, z.objectOutputType<{
+    summary: z.ZodObject<{
+        rob_judgment: z.ZodString;
+        downgrade: z.ZodBoolean;
+        rationale: z.ZodString;
+    }, "passthrough", z.ZodTypeAny, z.objectOutputType<{
+        rob_judgment: z.ZodString;
+        downgrade: z.ZodBoolean;
+        rationale: z.ZodString;
+    }, z.ZodTypeAny, "passthrough">, z.objectInputType<{
+        rob_judgment: z.ZodString;
+        downgrade: z.ZodBoolean;
+        rationale: z.ZodString;
+    }, z.ZodTypeAny, "passthrough">>;
+    overall_certainty_start: z.ZodEnum<["High", "Low"]>;
+}, z.ZodTypeAny, "passthrough">, z.objectInputType<{
+    summary: z.ZodObject<{
+        rob_judgment: z.ZodString;
+        downgrade: z.ZodBoolean;
+        rationale: z.ZodString;
+    }, "passthrough", z.ZodTypeAny, z.objectOutputType<{
+        rob_judgment: z.ZodString;
+        downgrade: z.ZodBoolean;
+        rationale: z.ZodString;
+    }, z.ZodTypeAny, "passthrough">, z.objectInputType<{
+        rob_judgment: z.ZodString;
+        downgrade: z.ZodBoolean;
+        rationale: z.ZodString;
+    }, z.ZodTypeAny, "passthrough">>;
+    overall_certainty_start: z.ZodEnum<["High", "Low"]>;
+}, z.ZodTypeAny, "passthrough">>;
+export type RobResultsInput = z.infer<typeof RobResultsSchema>;
+/**
+ * Output of cost_effectiveness_model, optionally passed for
+ * downstream sensitivity narrative. Kept loose (passthrough) because the CEA
+ * output is large and we don't need to validate every nested PSA bin.
+ */
+export declare const CEModelResultSchema: z.ZodObject<{
+    icer: z.ZodOptional<z.ZodNumber>;
+    incremental_costs: z.ZodOptional<z.ZodNumber>;
+    incremental_qalys: z.ZodOptional<z.ZodNumber>;
+}, "passthrough", z.ZodTypeAny, z.objectOutputType<{
+    icer: z.ZodOptional<z.ZodNumber>;
+    incremental_costs: z.ZodOptional<z.ZodNumber>;
+    incremental_qalys: z.ZodOptional<z.ZodNumber>;
+}, z.ZodTypeAny, "passthrough">, z.objectInputType<{
+    icer: z.ZodOptional<z.ZodNumber>;
+    incremental_costs: z.ZodOptional<z.ZodNumber>;
+    incremental_qalys: z.ZodOptional<z.ZodNumber>;
+}, z.ZodTypeAny, "passthrough">>;
+export type CEModelResultInput = z.infer<typeof CEModelResultSchema>;
+//# sourceMappingURL=dossierInputSchemas.d.ts.map

package/dist/schemas/dossierInputSchemas.d.ts.map

@@ -0,0 +1 @@
+{"version":3,"file":"dossierInputSchemas.d.ts","sourceRoot":"","sources":["../../src/schemas/dossierInputSchemas.ts"],"names":[],"mappings":"AAAA;;;;;;;;;;GAUG;AAEH,OAAO,EAAE,CAAC,EAAE,MAAM,KAAK,CAAC;AAExB;;;;GAIG;AACH,eAAO,MAAM,sBAAsB;;;;;;;;;;;;;;;;;;;;;;;;;;;gCAWnB,CAAC;AAEjB,MAAM,MAAM,qBAAqB,GAAG,CAAC,CAAC,KAAK,CAAC,OAAO,sBAAsB,CAAC,CAAC;AAE3E;;;;GAIG;AACH,eAAO,MAAM,gBAAgB;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;gCAWb,CAAC;AAEjB,MAAM,MAAM,eAAe,GAAG,CAAC,CAAC,KAAK,CAAC,OAAO,gBAAgB,CAAC,CAAC;AAE/D;;;;GAIG;AACH,eAAO,MAAM,mBAAmB;;;;;;;;;;;;gCAMhB,CAAC;AAEjB,MAAM,MAAM,kBAAkB,GAAG,CAAC,CAAC,KAAK,CAAC,OAAO,mBAAmB,CAAC,CAAC"}

package/dist/schemas/dossierInputSchemas.js

@@ -0,0 +1,59 @@
+/**
+ * Zod schemas for inputs that htaDossierPrep accepts from upstream tools.
+ *
+ * Previously these were `z.any()` — which silently accepted garbage and let
+ * malformed shapes crash deep inside `generateGradeTable`. With proper
+ * schemas, the tool boundary rejects bad input with a field-level error
+ * message that's actionable for the caller (Claude, ChatGPT, or a human).
+ *
+ * `passthrough()` is used so unknown fields are preserved (forward-compat
+ * for adding new fields without breaking older callers).
+ */
+import { z } from "zod";
+/**
+ * Single literature search result. Accepts the canonical shape produced by
+ * literature_search; in practice many fields may be absent (e.g., user pastes
+ * a cherry-picked subset), so only title + abstract are required.
+ */
+export const LiteratureResultSchema = z
+    .object({
+    id: z.string().optional(),
+    source: z.string().optional(),
+    title: z.string().min(1),
+    authors: z.array(z.string()).optional(),
+    date: z.string().optional(),
+    study_type: z.string().optional(),
+    abstract: z.string(),
+    url: z.string().optional(),
+})
+    .passthrough();
+/**
+ * Output of the risk_of_bias tool, intended to be passed back into
+ * hta_dossier so the GRADE table uses structured RoB judgments instead of
+ * the heuristic fallback.
+ */
+export const RobResultsSchema = z
+    .object({
+    summary: z
+        .object({
+        rob_judgment: z.string().min(1),
+        downgrade: z.boolean(),
+        rationale: z.string(),
+    })
+        .passthrough(),
+    overall_certainty_start: z.enum(["High", "Low"]),
+})
+    .passthrough();
+/**
+ * Output of cost_effectiveness_model, optionally passed for
+ * downstream sensitivity narrative. Kept loose (passthrough) because the CEA
+ * output is large and we don't need to validate every nested PSA bin.
+ */
+export const CEModelResultSchema = z
+    .object({
+    icer: z.number().optional(),
+    incremental_costs: z.number().optional(),
+    incremental_qalys: z.number().optional(),
+})
+    .passthrough();
+//# sourceMappingURL=dossierInputSchemas.js.map

package/dist/schemas/dossierInputSchemas.js.map

@@ -0,0 +1 @@
+{"version":3,"file":"dossierInputSchemas.js","sourceRoot":"","sources":["../../src/schemas/dossierInputSchemas.ts"],"names":[],"mappings":"AAAA;;;;;;;;;;GAUG;AAEH,OAAO,EAAE,CAAC,EAAE,MAAM,KAAK,CAAC;AAExB;;;;GAIG;AACH,MAAM,CAAC,MAAM,sBAAsB,GAAG,CAAC;KACpC,MAAM,CAAC;IACN,EAAE,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,QAAQ,EAAE;IACzB,MAAM,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,QAAQ,EAAE;IAC7B,KAAK,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,GAAG,CAAC,CAAC,CAAC;IACxB,OAAO,EAAE,CAAC,CAAC,KAAK,CAAC,CAAC,CAAC,MAAM,EAAE,CAAC,CAAC,QAAQ,EAAE;IACvC,IAAI,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,QAAQ,EAAE;IAC3B,UAAU,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,QAAQ,EAAE;IACjC,QAAQ,EAAE,CAAC,CAAC,MAAM,EAAE;IACpB,GAAG,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,QAAQ,EAAE;CAC3B,CAAC;KACD,WAAW,EAAE,CAAC;AAIjB;;;;GAIG;AACH,MAAM,CAAC,MAAM,gBAAgB,GAAG,CAAC;KAC9B,MAAM,CAAC;IACN,OAAO,EAAE,CAAC;SACP,MAAM,CAAC;QACN,YAAY,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,GAAG,CAAC,CAAC,CAAC;QAC/B,SAAS,EAAE,CAAC,CAAC,OAAO,EAAE;QACtB,SAAS,EAAE,CAAC,CAAC,MAAM,EAAE;KACtB,CAAC;SACD,WAAW,EAAE;IAChB,uBAAuB,EAAE,CAAC,CAAC,IAAI,CAAC,CAAC,MAAM,EAAE,KAAK,CAAC,CAAC;CACjD,CAAC;KACD,WAAW,EAAE,CAAC;AAIjB;;;;GAIG;AACH,MAAM,CAAC,MAAM,mBAAmB,GAAG,CAAC;KACjC,MAAM,CAAC;IACN,IAAI,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,QAAQ,EAAE;IAC3B,iBAAiB,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,QAAQ,EAAE;IACxC,iBAAiB,EAAE,CAAC,CAAC,MAAM,EAAE,CAAC,QAAQ,EAAE;CACzC,CAAC;KACD,WAAW,EAAE,CAAC"}

package/dist/server.js

@@ -26,7 +26,7 @@ import { handleValidateLinks, validateLinksToolSchema, } from "./tools/validateL
 import { handleUtilityValueSet, utilityValueSetToolSchema, } from "./tools/utilityValueSet.js";
 import { handleItcFeasibility, itcFeasibilityToolSchema, } from "./tools/itcFeasibility.js";
 import { randomUUID } from "node:crypto";
-import { trackToolCall, trackSession, shutdownAnalytics } from "./analytics.js";
+import { trackToolCall, trackSession, shutdownAnalytics, inferSurface, } from "./analytics.js";
 import { createServer } from "node:http";
 import { readFile } from "node:fs/promises";
 // Pre-built HEOR workflow prompts for Claude Desktop slash-command discovery
@@ -96,7 +96,7 @@ const HEOR_PROMPTS = [
         ],
     },
 ];
-function createMcpServer() {
+function createMcpServer(surfaceRef = { value: "direct_mcp" }) {
     const server = new Server({ name: "heor-agent-mcp", version: PKG_VERSION }, {
         capabilities: {
             tools: {},
@@ -214,13 +214,18 @@ function createMcpServer() {
                     result = await handleItcFeasibility(args);
                     break;
                 default:
-                    trackToolCall(name, Date.now() - callStart, "error");
+                    trackToolCall(name, Date.now() - callStart, "error", undefined, {
+                        surface: surfaceRef.value,
+                        error_class: "unknown_tool",
+                    });
                     return {
                         content: [{ type: "text", text: `Unknown tool: ${name}` }],
                         isError: true,
                     };
             }
-            trackToolCall(name, Date.now() - callStart, "ok");
+            trackToolCall(name, Date.now() - callStart, "ok", undefined, {
+                surface: surfaceRef.value,
+            });
             const content = typeof result.content === "string"
                 ? result.content
                 : JSON.stringify(result.content, null, 2);
@@ -231,6 +236,7 @@ function createMcpServer() {
         catch (err) {
             const message = err instanceof Error ? err.message : String(err);
             trackToolCall(name, Date.now() - callStart, "error", undefined, {
+                surface: surfaceRef.value,
                 error: message,
             });
             return {
@@ -384,13 +390,21 @@ async function runHttp(port) {
                         }));
                         return;
                     }
-                    // New session
-                    const server = createMcpServer();
+                    // New session — capture clientInfo.name from initialize body so
+                    // every subsequent tool_call event can be tagged with surface
+                    // (claude_anthropic_web / chatgpt_adapter / claude_desktop / etc.)
+                    const clientName = body?.params?.clientInfo?.name;
+                    const surface = inferSurface(clientName);
+                    const surfaceRef = { value: surface };
+                    const server = createMcpServer(surfaceRef);
                     transport = new StreamableHTTPServerTransport({
                         sessionIdGenerator: () => randomUUID(),
                         onsessioninitialized: (id) => {
                             sessions.set(id, { transport, lastActivity: Date.now() });
-                            trackSession("session_start", id);
+                            trackSession("session_start", id, {
+                                surface,
+                                client_name: clientName ?? "unknown",
+                            });
                         },
                     });
                     transport.onclose = () => {

package/dist/server.js.map

@@ -1 +1 @@
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package/dist/tools/htaDossierPrep.d.ts.map

@@ -1 +1 @@
-{"version":3,"file":"htaDossierPrep.d.ts","sourceRoot":"","sources":["../../src/tools/htaDossierPrep.ts"],"names":[],"mappings":"AACA,OAAO,KAAK,EAEV,UAAU,EAGX,MAAM,uBAAuB,CAAC;AAupB/B,wBAAsB,oBAAoB,CACxC,SAAS,EAAE,OAAO,GACjB,OAAO,CAAC,UAAU,CAAC,CAmJrB;AAED,eAAO,MAAM,wBAAwB;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;CAyFpC,CAAC"}
+{"version":3,"file":"htaDossierPrep.d.ts","sourceRoot":"","sources":["../../src/tools/htaDossierPrep.ts"],"names":[],"mappings":"AACA,OAAO,KAAK,EAEV,UAAU,EAGX,MAAM,uBAAuB,CAAC;AA8pB/B,wBAAsB,oBAAoB,CACxC,SAAS,EAAE,OAAO,GACjB,OAAO,CAAC,UAAU,CAAC,CAmJrB;AAED,eAAO,MAAM,wBAAwB;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;CAyFpC,CAAC"}

package/dist/tools/htaDossierPrep.js

@@ -1,4 +1,5 @@
 import { z } from "zod";
+import { LiteratureResultSchema, RobResultsSchema, CEModelResultSchema, } from "../schemas/dossierInputSchemas.js";
 const DossierSchema = z.object({
     hta_body: z.enum(["nice", "ema", "fda", "iqwig", "has", "jca", "gvd"]),
     submission_type: z.enum([
@@ -11,8 +12,10 @@ const DossierSchema = z.object({
     ]),
     drug_name: z.string().min(1),
     indication: z.string().min(1),
-    evidence_summary: z.union([z.string(), z.array(z.any())]).optional(),
-    model_results: z.any().optional(),
+    evidence_summary: z
+        .union([z.string(), z.array(LiteratureResultSchema)])
+        .optional(),
+    model_results: CEModelResultSchema.optional(),
     picos: z
         .array(z.object({
         id: z.string(),
@@ -23,7 +26,7 @@ const DossierSchema = z.object({
         .optional(),
     output_format: z.enum(["text", "json", "docx"]).optional(),
     project: z.string().optional(),
-    rob_results: z.any().optional(),
+    rob_results: RobResultsSchema.optional(),
     heterogeneity_per_outcome: z
         .record(z.string(), z.object({
         i_squared_pct: z.number().min(0).max(100),

package/dist/tools/htaDossierPrep.js.map

@@ -1 +1 @@
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package/package.json

@@ -1,6 +1,6 @@
 {
   "name": "heor-agent-mcp",
-  "version": "1.0.3",
+  "version": "1.0.4",
   "mcpName": "io.github.neptun2000/heor-agent",
   "license": "MIT",
   "author": "mnaumov",