ezmedicationinput 0.1.46 → 0.1.48

package/dist/index.cjs

@@ -103,11 +103,15 @@ __export(index_exports, {
   getBodySiteCodeAsync: () => getBodySiteCodeAsync,
   getBodySiteText: () => getBodySiteText,
   getBodySiteTextAsync: () => getBodySiteTextAsync,
+  getDoseUnitApproximation: () => getDoseUnitApproximation,
+  getDoseUnitKind: () => getDoseUnitKind,
+  getDoseUnitSemantics: () => getDoseUnitSemantics,
   getRegisteredSigLocalizations: () => getRegisteredSigLocalizations,
   hasSnomedBodySiteLateralityPostcoordination: () => hasSnomedBodySiteLateralityPostcoordination,
   hasSnomedFindingSitePostcoordination: () => hasSnomedFindingSitePostcoordination,
   hasSnomedTopographicalModifierPostcoordination: () => hasSnomedTopographicalModifierPostcoordination,
   lintSig: () => lintSig,
+  listDoseUnitTerminology: () => listDoseUnitTerminology,
   listSupportedBodySiteGrammar: () => listSupportedBodySiteGrammar,
   listSupportedBodySiteText: () => listSupportedBodySiteText,
   lookupBodySite: () => lookupBodySite,
@@ -132,17 +136,17 @@ module.exports = __toCommonJS(index_exports);
 
 // src/prn.ts
 function getCanonicalPrnReasonText(reason) {
-  var _a, _b;
-  return (_b = reason == null ? void 0 : reason.text) != null ? _b : (_a = reason == null ? void 0 : reason.coding) == null ? void 0 : _a.display;
+  var _a2, _b;
+  return (_b = reason == null ? void 0 : reason.text) != null ? _b : (_a2 = reason == null ? void 0 : reason.coding) == null ? void 0 : _a2.display;
 }
 function joinCanonicalPrnReasonTexts(reasons, conjunction = "or") {
-  var _a;
+  var _a2;
   if (!(reasons == null ? void 0 : reasons.length)) {
     return void 0;
   }
   const texts = [];
   for (const reason of reasons) {
-    const text = (_a = getCanonicalPrnReasonText(reason)) == null ? void 0 : _a.trim();
+    const text = (_a2 = getCanonicalPrnReasonText(reason)) == null ? void 0 : _a2.trim();
     if (!text) {
       continue;
     }
@@ -173,8 +177,8 @@ function joinCanonicalPrnReasonTexts(reasons, conjunction = "or") {
   }
 }
 function getPreferredCanonicalPrnReasonText(reason, reasons, conjunction = "or") {
-  var _a;
-  const direct = (_a = getCanonicalPrnReasonText(reason)) == null ? void 0 : _a.trim();
+  var _a2;
+  const direct = (_a2 = getCanonicalPrnReasonText(reason)) == null ? void 0 : _a2.trim();
   if (!(reasons == null ? void 0 : reasons.length)) {
     return direct;
   }
@@ -478,10 +482,10 @@ function cloneI18nRecord(i18n) {
   return i18n ? __spreadValues({}, i18n) : void 0;
 }
 function cloneExtension(extension) {
-  var _a, _b, _c, _d;
+  var _a2, _b, _c, _d;
   return {
     url: extension.url,
-    extension: (_a = extension.extension) == null ? void 0 : _a.map(cloneExtension),
+    extension: (_a2 = extension.extension) == null ? void 0 : _a2.map(cloneExtension),
     valueCode: extension.valueCode,
     valueString: extension.valueString,
     valueCoding: extension.valueCoding ? {
@@ -496,14 +500,14 @@ function cloneExtension(extension) {
       text: extension.valueCodeableConcept.text,
       _text: clonePrimitiveElement(extension.valueCodeableConcept._text),
       coding: (_c = extension.valueCodeableConcept.coding) == null ? void 0 : _c.map((coding) => {
-        var _a2;
+        var _a3;
         return {
           system: coding.system,
           code: coding.code,
           display: coding.display,
           _display: clonePrimitiveElement(coding._display),
           i18n: cloneI18nRecord(coding.i18n),
-          extension: (_a2 = coding.extension) == null ? void 0 : _a2.map(cloneExtension)
+          extension: (_a3 = coding.extension) == null ? void 0 : _a3.map(cloneExtension)
         };
       }),
       extension: (_d = extension.valueCodeableConcept.extension) == null ? void 0 : _d.map(cloneExtension)
@@ -514,8 +518,8 @@ function cloneExtensions(extensions) {
   return (extensions == null ? void 0 : extensions.length) ? extensions.map(cloneExtension) : void 0;
 }
 function clonePrimitiveElement(element) {
-  var _a;
-  if (!((_a = element == null ? void 0 : element.extension) == null ? void 0 : _a.length)) {
+  var _a2;
+  if (!((_a2 = element == null ? void 0 : element.extension) == null ? void 0 : _a2.length)) {
     return void 0;
   }
   return {
@@ -538,9 +542,9 @@ function buildTranslationExtension(locale, content) {
   };
 }
 function buildTranslationPrimitiveElement(translations, base) {
-  var _a, _b;
+  var _a2, _b;
   const nextExtensions = [];
-  const baseExtensions = (_a = base == null ? void 0 : base.extension) != null ? _a : [];
+  const baseExtensions = (_a2 = base == null ? void 0 : base.extension) != null ? _a2 : [];
   for (const extension of baseExtensions) {
     if (extension.url !== FHIR_TRANSLATION_EXTENSION_URL) {
       nextExtensions.push(cloneExtension(extension));
@@ -564,8 +568,8 @@ function buildTranslationPrimitiveElement(translations, base) {
   };
 }
 function getTranslationParts(extension) {
-  var _a, _b;
-  const parts = (_a = extension.extension) != null ? _a : [];
+  var _a2, _b;
+  const parts = (_a2 = extension.extension) != null ? _a2 : [];
   let locale;
   let content;
   for (const part of parts) {
@@ -583,9 +587,9 @@ function getTranslationParts(extension) {
   return { locale, content };
 }
 function getPrimitiveTranslation(element, locale) {
-  var _a;
+  var _a2;
   const targetLocale = normalizeLocaleKey(locale);
-  if (!targetLocale || !((_a = element == null ? void 0 : element.extension) == null ? void 0 : _a.length)) {
+  if (!targetLocale || !((_a2 = element == null ? void 0 : element.extension) == null ? void 0 : _a2.length)) {
     return void 0;
   }
   let languagePrefixMatch;
@@ -640,19 +644,19 @@ function cloneBodySiteCoding(coding) {
   };
 }
 function bodySiteCodingToFhir(coding) {
-  var _a;
+  var _a2;
   if (!(coding == null ? void 0 : coding.code)) {
     return void 0;
   }
   return {
-    system: (_a = coding.system) != null ? _a : SNOMED_SYSTEM2,
+    system: (_a2 = coding.system) != null ? _a2 : SNOMED_SYSTEM2,
     code: coding.code,
     display: coding.display
   };
 }
 function firstCodingWithCode(concept) {
-  var _a;
-  return (_a = concept == null ? void 0 : concept.coding) == null ? void 0 : _a.find((coding) => Boolean(coding.code));
+  var _a2;
+  return (_a2 = concept == null ? void 0 : concept.coding) == null ? void 0 : _a2.find((coding) => Boolean(coding.code));
 }
 function cloneBodySiteSpatialRelation(relation) {
   if (!relation) {
@@ -705,8 +709,8 @@ function buildBodySiteSpatialRelationExtensions(relation) {
   return extension ? [extension] : void 0;
 }
 function parseBodySiteSpatialRelationExtension(concept) {
-  var _a, _b, _c, _d, _e, _f, _g, _h, _i, _j;
-  const extension = (_a = concept == null ? void 0 : concept.extension) == null ? void 0 : _a.find(
+  var _a2, _b, _c, _d, _e, _f, _g, _h, _i, _j;
+  const extension = (_a2 = concept == null ? void 0 : concept.extension) == null ? void 0 : _a2.find(
     (candidate) => candidate.url === BODY_SITE_SPATIAL_RELATION_EXTENSION_URL
   );
   if (!((_b = extension == null ? void 0 : extension.extension) == null ? void 0 : _b.length)) {
@@ -759,8 +763,8 @@ function buildSnomedBodySiteLateralityPostcoordinationCode(siteCode, lateralityC
   return `${siteCode}${SNOMED_LATERALITY_MARKER}${lateralityCode}`;
 }
 function parseSnomedBodySiteTopographicalModifierPostcoordinationCode(code) {
-  var _a;
-  const markerIndex = (_a = code == null ? void 0 : code.indexOf(SNOMED_TOPOGRAPHICAL_MODIFIER_MARKER)) != null ? _a : -1;
+  var _a2;
+  const markerIndex = (_a2 = code == null ? void 0 : code.indexOf(SNOMED_TOPOGRAPHICAL_MODIFIER_MARKER)) != null ? _a2 : -1;
   if (!code || markerIndex < 0) {
     return void 0;
   }
@@ -772,8 +776,8 @@ function parseSnomedBodySiteTopographicalModifierPostcoordinationCode(code) {
   return { siteCode, modifierCode };
 }
 function parseSnomedBodySiteLateralityPostcoordinationCode(code) {
-  var _a;
-  const markerIndex = (_a = code == null ? void 0 : code.indexOf(SNOMED_LATERALITY_MARKER)) != null ? _a : -1;
+  var _a2;
+  const markerIndex = (_a2 = code == null ? void 0 : code.indexOf(SNOMED_LATERALITY_MARKER)) != null ? _a2 : -1;
   if (!code || markerIndex < 0) {
     return void 0;
   }
@@ -785,8 +789,8 @@ function parseSnomedBodySiteLateralityPostcoordinationCode(code) {
   return { siteCode, lateralityCode };
 }
 function parseSnomedFindingSitePostcoordinationCode(code) {
-  var _a;
-  const markerIndex = (_a = code == null ? void 0 : code.indexOf(SNOMED_FINDING_SITE_ATTRIBUTE_MARKER)) != null ? _a : -1;
+  var _a2;
+  const markerIndex = (_a2 = code == null ? void 0 : code.indexOf(SNOMED_FINDING_SITE_ATTRIBUTE_MARKER)) != null ? _a2 : -1;
   if (!code || markerIndex < 0) {
     return void 0;
   }
@@ -798,8 +802,8 @@ function parseSnomedFindingSitePostcoordinationCode(code) {
   return { focusCode, siteCode };
 }
 function buildSnomedFindingSiteCoding(params) {
-  var _a, _b, _c, _d, _e, _f;
-  const focusCode = (_a = params.focusCoding) == null ? void 0 : _a.code;
+  var _a2, _b, _c, _d, _e, _f;
+  const focusCode = (_a2 = params.focusCoding) == null ? void 0 : _a2.code;
   const siteCode = (_b = params.siteCoding) == null ? void 0 : _b.code;
   if (!focusCode || !siteCode || hasSnomedFindingSitePostcoordination(focusCode)) {
     return void 0;
@@ -905,10 +909,10 @@ var ROUTE_SNOMED = objectFromEntries(
 );
 var ROUTE_TEXT = objectFromEntries(
   ROUTE_SNOMED_ENTRIES.map(([routeCode, meta]) => {
-    var _a;
+    var _a2;
     return [
       routeCode,
-      (_a = ROUTE_TEXT_OVERRIDES[routeCode]) != null ? _a : defaultRouteText(meta.display)
+      (_a2 = ROUTE_TEXT_OVERRIDES[routeCode]) != null ? _a2 : defaultRouteText(meta.display)
     ];
   })
 );
@@ -1136,7 +1140,7 @@ var LATERALIZABLE_DIGIT_BODY_SITES = [
   }
 ];
 function buildLateralizedDigitBodySiteEntries() {
-  var _a;
+  var _a2;
   const entries = [];
   for (const site of LATERALIZABLE_DIGIT_BODY_SITES) {
     for (const laterality of BODY_SITE_LATERALITIES) {
@@ -1161,7 +1165,7 @@ function buildLateralizedDigitBodySiteEntries() {
             display: text
           },
           text,
-          routeHint: (_a = site.routeHint) != null ? _a : RouteCode["Topical route"]
+          routeHint: (_a2 = site.routeHint) != null ? _a2 : RouteCode["Topical route"]
         }
       });
     }
@@ -2207,6 +2211,18 @@ var STATIC_UNIT_SYNONYMS = {
   capfuls: "capful",
   scoop: "scoop",
   scoops: "scoop",
+  tube: "tube",
+  tubes: "tube",
+  bottle: "bottle",
+  bottles: "bottle",
+  container: "container",
+  containers: "container",
+  jar: "jar",
+  jars: "jar",
+  packet: "packet",
+  packets: "packet",
+  sachet: "sachet",
+  sachets: "sachet",
   application: "application",
   applications: "application",
   ribbon: "ribbon",
@@ -3804,8 +3820,8 @@ var DEFAULT_PRN_REASON_SOURCE = [
   }
 ];
 var DEFAULT_PRN_REASON_ENTRIES = DEFAULT_PRN_REASON_SOURCE.map((source) => {
-  var _a, _b, _c;
-  const canonicalTerm = (_c = (_b = source.definition.text) != null ? _b : (_a = source.definition.coding) == null ? void 0 : _a.display) != null ? _c : source.names[0];
+  var _a2, _b, _c;
+  const canonicalTerm = (_c = (_b = source.definition.text) != null ? _b : (_a2 = source.definition.coding) == null ? void 0 : _a2.display) != null ? _c : source.names[0];
   const terms = [];
   const seen = /* @__PURE__ */ new Set();
   const pushTerm = (value) => {
@@ -3852,13 +3868,13 @@ var DEFAULT_PRN_REASON_DEFINITIONS = objectFromEntries(
   }, [])
 );
 function findPrnReasonDefinitionByCoding(system, code) {
-  var _a;
-  return (_a = DEFAULT_PRN_REASON_SOURCE.find(
+  var _a2;
+  return (_a2 = DEFAULT_PRN_REASON_SOURCE.find(
     (source) => {
-      var _a2, _b;
-      return ((_a2 = source.definition.coding) == null ? void 0 : _a2.system) === system && ((_b = source.definition.coding) == null ? void 0 : _b.code) === code;
+      var _a3, _b;
+      return ((_a3 = source.definition.coding) == null ? void 0 : _a3.system) === system && ((_b = source.definition.coding) == null ? void 0 : _b.code) === code;
     }
-  )) == null ? void 0 : _a.definition;
+  )) == null ? void 0 : _a2.definition;
 }
 
 // src/hpsg/lexical-classes.json
@@ -3956,8 +3972,122 @@ var lexical_classes_default = {
   },
   compoundDoseUnits: [
     { head: "cm", tails: ["ribbon", "ribbons"], unit: "cm ribbon" },
-    { head: "fingertip", tails: ["unit", "units"], unit: "fingertip unit" }
+    { head: "cm", tails: ["strip", "strips"], unit: "cm strip" },
+    { head: "cm", tails: ["line", "lines"], unit: "cm line" },
+    { head: "inch", tails: ["ribbon", "ribbons", "strip", "strips"], unit: "inch ribbon" },
+    { head: "inch", tails: ["line", "lines"], unit: "inch line" },
+    { head: "fingertip", tails: ["unit", "units"], unit: "FTU" },
+    { head: "eye", tails: ["drop", "drops"], unit: "drop" },
+    { head: "pea-sized", tails: ["amount"], unit: "pea-sized amount" },
+    { head: "\u0E40\u0E21\u0E47\u0E14\u0E16\u0E31\u0E48\u0E27", tails: [], unit: "pea-sized amount" },
+    { head: "\u0E40\u0E21\u0E47\u0E14\u0E16\u0E31\u0E48\u0E27\u0E40\u0E02\u0E35\u0E22\u0E27", tails: [], unit: "pea-sized amount" },
+    { head: "\u0E40\u0E21\u0E25\u0E47\u0E14\u0E16\u0E31\u0E48\u0E27", tails: [], unit: "pea-sized amount" },
+    { head: "\u0E02\u0E19\u0E32\u0E14\u0E40\u0E21\u0E47\u0E14\u0E16\u0E31\u0E48\u0E27", tails: [], unit: "pea-sized amount" },
+    { head: "\u0E02\u0E19\u0E32\u0E14\u0E40\u0E21\u0E47\u0E14\u0E16\u0E31\u0E48\u0E27\u0E40\u0E02\u0E35\u0E22\u0E27", tails: [], unit: "pea-sized amount" },
+    { head: "\u0E02\u0E19\u0E32\u0E14\u0E40\u0E21\u0E25\u0E47\u0E14\u0E16\u0E31\u0E48\u0E27", tails: [], unit: "pea-sized amount" },
+    {
+      head: "pea",
+      tails: [],
+      tailSequences: [["sized", "amount"], ["size", "amount"]],
+      unit: "pea-sized amount"
+    },
+    { head: "hand", tails: ["print", "prints"], unit: "handprint" },
+    { head: "percent", tails: ["bsa", "tbsa"], unit: "% BSA" },
+    { head: "shot", tails: ["glass", "glasses"], unit: "shot glass" },
+    { head: "finger", tails: ["length", "lengths"], unit: "finger length" },
+    { head: "two-finger", tails: ["rule", "method"], unit: "finger length" },
+    {
+      head: "two",
+      tails: [],
+      tailSequences: [["finger", "rule"], ["finger", "method"]],
+      unit: "finger length"
+    },
+    { head: "full", tails: ["applicator", "applicators"], unit: "applicatorful" },
+    {
+      head: "cap",
+      tails: [],
+      tailSequences: [["to", "line"], ["filled", "to", "line"]],
+      unit: "capful"
+    },
+    { head: "stick", tails: ["pack", "packs"], unit: "stick-pack" },
+    { head: "unit-dose", tails: ["vial", "vials"], unit: "vial" },
+    {
+      head: "unit",
+      tails: [],
+      tailSequences: [["dose", "vial"], ["dose", "vials"]],
+      unit: "vial"
+    },
+    { head: "insulin", tails: ["unit", "units"], unit: "U" },
+    { head: "usp", tails: ["unit", "units"], unit: "U" },
+    { head: "pen", tails: ["click", "clicks"], unit: "click" },
+    { head: "dial", tails: ["click", "clicks"], unit: "click" },
+    { head: "transdermal", tails: ["system", "systems"], unit: "patch" }
   ],
+  implicitSingleDoseUnits: ["pea-sized amount", "finger length"],
+  percentBodyAreaUnits: {
+    bsa: "% BSA",
+    tbsa: "% BSA"
+  },
+  doseFractionWords: {
+    half: 0.5,
+    quarter: 0.25,
+    fourth: 0.25,
+    third: 0.3333333333333333,
+    fifth: 0.2,
+    sixth: 0.16666666666666666,
+    seventh: 0.14285714285714285,
+    eighth: 0.125,
+    ninth: 0.1111111111111111,
+    tenth: 0.1,
+    eleventh: 0.09090909090909091,
+    twelfth: 0.08333333333333333,
+    whole: 1,
+    entire: 1,
+    full: 1
+  },
+  doseFractionDenominatorWords: {
+    half: 0.5,
+    halves: 0.5,
+    quarter: 0.25,
+    quarters: 0.25,
+    fourth: 0.25,
+    fourths: 0.25,
+    third: 0.3333333333333333,
+    thirds: 0.3333333333333333,
+    fifth: 0.2,
+    fifths: 0.2,
+    sixth: 0.16666666666666666,
+    sixths: 0.16666666666666666,
+    seventh: 0.14285714285714285,
+    sevenths: 0.14285714285714285,
+    eighth: 0.125,
+    eighths: 0.125,
+    ninth: 0.1111111111111111,
+    ninths: 0.1111111111111111,
+    tenth: 0.1,
+    tenths: 0.1,
+    eleventh: 0.09090909090909091,
+    elevenths: 0.09090909090909091,
+    twelfth: 0.08333333333333333,
+    twelfths: 0.08333333333333333
+  },
+  doseNumberWords: {
+    a: 1,
+    an: 1,
+    one: 1,
+    two: 2,
+    three: 3,
+    four: 4,
+    five: 5,
+    six: 6,
+    seven: 7,
+    eight: 8,
+    nine: 9,
+    ten: 10,
+    eleven: 11,
+    twelve: 12
+  },
+  doseUnitConnectors: ["of", "a", "an", "the"],
   millionDoseMultiplierTokens: ["m"],
   scheduleUnitSeparatorTokens: ["/"],
   compactListSeparators: ["/"],
@@ -4081,6 +4211,7 @@ var lexical_classes_default = {
     "dont",
     "drink",
     "empty",
+    "gently",
     "liberally",
     "may",
     "might",
@@ -4093,10 +4224,24 @@ var lexical_classes_default = {
     "should",
     "slowly",
     "sparingly",
+    "thickly",
+    "thick",
+    "thinly",
+    "thin",
     "use",
     "with",
     "without"
   ],
+  siteTrailingInstructionWords: [
+    "gently",
+    "liberally",
+    "slowly",
+    "sparingly",
+    "thick",
+    "thickly",
+    "thin",
+    "thinly"
+  ],
   workflowContinuationLicenses: ["with each", "after each", "the *event", "sun exposure"],
   asNeededLeadPhrases: ["as needed"],
   prnBreakingCoordinators: [",", "/"],
@@ -4144,9 +4289,9 @@ function routeCodeSet(labels) {
   );
 }
 function eventTimingMap(record) {
-  var _a, _b;
+  var _a2, _b;
   const map = /* @__PURE__ */ new Map();
-  const nodeEnv = (_b = (_a = globalThis.process) == null ? void 0 : _a.env) == null ? void 0 : _b.NODE_ENV;
+  const nodeEnv = (_b = (_a2 = globalThis.process) == null ? void 0 : _a2.env) == null ? void 0 : _b.NODE_ENV;
   const shouldWarn = nodeEnv !== "production";
   for (const key in record) {
     if (Object.prototype.hasOwnProperty.call(record, key)) {
@@ -4197,6 +4342,15 @@ function stringEntries(record) {
 function numberRecord(record) {
   return __spreadValues({}, record);
 }
+function numberEntries(record) {
+  const entries = [];
+  for (const key in record) {
+    if (Object.prototype.hasOwnProperty.call(record, key)) {
+      entries.push([key, record[key]]);
+    }
+  }
+  return entries;
+}
 function periodUnitRecord(record) {
   const result = /* @__PURE__ */ new Map();
   for (const [token, label] of stringEntries(record)) {
@@ -4269,6 +4423,20 @@ var SITE_ROUTE_HINTS_ALLOWED_IN_GRAMMAR = routeCodeSet(lexical_classes_default.s
 var PRODUCT_METHOD_TEXT = lexical_classes_default.productMethodText;
 var PRODUCT_METHOD_THAI = lexical_classes_default.productMethodThai;
 var COMPOUND_DOSE_UNITS = lexical_classes_default.compoundDoseUnits;
+var IMPLICIT_SINGLE_DOSE_UNITS = setOf(lexical_classes_default.implicitSingleDoseUnits);
+var PERCENT_BODY_AREA_UNITS = new Map(
+  stringEntries(lexical_classes_default.percentBodyAreaUnits)
+);
+var DOSE_FRACTION_WORDS = new Map(
+  numberEntries(lexical_classes_default.doseFractionWords)
+);
+var DOSE_FRACTION_DENOMINATOR_WORDS = new Map(
+  numberEntries(lexical_classes_default.doseFractionDenominatorWords)
+);
+var DOSE_NUMBER_WORDS = new Map(
+  numberEntries(lexical_classes_default.doseNumberWords)
+);
+var DOSE_UNIT_CONNECTORS = setOf(lexical_classes_default.doseUnitConnectors);
 var MILLION_DOSE_MULTIPLIER_TOKENS = setOf(lexical_classes_default.millionDoseMultiplierTokens);
 var SCHEDULE_UNIT_SEPARATOR_TOKENS = setOf(lexical_classes_default.scheduleUnitSeparatorTokens);
 var COMPACT_LIST_SEPARATORS = setOf(lexical_classes_default.compactListSeparators);
@@ -4304,6 +4472,7 @@ var RANGE_CONNECTORS = setOf(lexical_classes_default.rangeConnectors);
 var DURATION_LEAD_TOKENS = setOf(lexical_classes_default.durationLeadTokens);
 var INSTRUCTION_LEADING_SEPARATORS = setOf(lexical_classes_default.instructionLeadingSeparators);
 var INSTRUCTION_START_WORDS = setOf(lexical_classes_default.instructionStartWords);
+var SITE_TRAILING_INSTRUCTION_WORDS = setOf(lexical_classes_default.siteTrailingInstructionWords);
 var WORKFLOW_CONTINUATION_LICENSES = setOf(lexical_classes_default.workflowContinuationLicenses);
 var AS_NEEDED_LEAD_PHRASES = setOf(lexical_classes_default.asNeededLeadPhrases);
 var PRN_BREAKING_COORDINATORS = setOf(lexical_classes_default.prnBreakingCoordinators);
@@ -4342,7 +4511,7 @@ var HAND_CONTEXT_KEYS = /* @__PURE__ */ new Set(["hand", "hands", "finger", "fin
 var FOOT_CONTEXT_KEYS = /* @__PURE__ */ new Set(["foot", "feet", "toe", "toes", "\u0E19\u0E34\u0E49\u0E27\u0E40\u0E17\u0E49\u0E32", "\u0E40\u0E17\u0E49\u0E32"]);
 var BODY_SITE_ALIAS_INDEXES = /* @__PURE__ */ new WeakMap();
 function buildOrGetBodySiteAliasIndex(map) {
-  var _a;
+  var _a2;
   const existing = BODY_SITE_ALIAS_INDEXES.get(map);
   if (existing) {
     return existing;
@@ -4353,7 +4522,7 @@ function buildOrGetBodySiteAliasIndex(map) {
     if (normalizedKey) {
       index.set(normalizedKey, definition);
     }
-    for (const alias of (_a = definition.aliases) != null ? _a : []) {
+    for (const alias of (_a2 = definition.aliases) != null ? _a2 : []) {
       const normalizedAlias = normalizeBodySiteKey(alias);
       if (normalizedAlias) {
         index.set(normalizedAlias, definition);
@@ -4414,7 +4583,7 @@ function resolveContextualBodySiteAlias(lookupCanonical, context) {
   return void 0;
 }
 function buildBodySiteCoding(definition) {
-  var _a;
+  var _a2;
   const coding = definition == null ? void 0 : definition.coding;
   if (!(coding == null ? void 0 : coding.code)) {
     return void 0;
@@ -4422,24 +4591,24 @@ function buildBodySiteCoding(definition) {
   return {
     code: coding.code,
     display: coding.display,
-    system: (_a = coding.system) != null ? _a : SNOMED_SYSTEM3
+    system: (_a2 = coding.system) != null ? _a2 : SNOMED_SYSTEM3
   };
 }
 function cloneBodySiteCode(coding) {
-  var _a;
+  var _a2;
   if (!(coding == null ? void 0 : coding.code)) {
     return void 0;
   }
   return {
     code: coding.code,
     display: coding.display,
-    system: (_a = coding.system) != null ? _a : SNOMED_SYSTEM3,
+    system: (_a2 = coding.system) != null ? _a2 : SNOMED_SYSTEM3,
     i18n: coding.i18n
   };
 }
 function lookupDefinitionForCanonical(canonical, customSiteMap) {
-  var _a;
-  return (_a = lookupBodySiteDefinition(customSiteMap, canonical)) != null ? _a : DEFAULT_BODY_SITE_SNOMED[canonical];
+  var _a2;
+  return (_a2 = lookupBodySiteDefinition(customSiteMap, canonical)) != null ? _a2 : DEFAULT_BODY_SITE_SNOMED[canonical];
 }
 function isAdjectivalSitePhrase(phrase) {
   const normalized = phrase.trim().toLowerCase();
@@ -4526,7 +4695,7 @@ function pickPreferredBodySitePhrase(canonical, definition, customSiteMap) {
   return normalizeBodySiteKey(best) === canonical ? void 0 : best;
 }
 function normalizeSiteDisplayText(text, customSiteMap) {
-  var _a, _b;
+  var _a2, _b;
   const trimmed = text.trim();
   if (!trimmed) {
     return trimmed;
@@ -4535,13 +4704,13 @@ function normalizeSiteDisplayText(text, customSiteMap) {
   if (!canonicalInput) {
     return trimmed;
   }
-  const directDefinition = (_a = lookupBodySiteDefinition(customSiteMap, canonicalInput)) != null ? _a : DEFAULT_BODY_SITE_SNOMED[canonicalInput];
+  const directDefinition = (_a2 = lookupBodySiteDefinition(customSiteMap, canonicalInput)) != null ? _a2 : DEFAULT_BODY_SITE_SNOMED[canonicalInput];
   if (directDefinition) {
     return (_b = directDefinition.text) != null ? _b : canonicalInput;
   }
   const resolvePreferred = (canonical) => {
-    var _a2, _b2, _c;
-    const definition = (_a2 = lookupBodySiteDefinition(customSiteMap, canonical)) != null ? _a2 : DEFAULT_BODY_SITE_SNOMED[canonical];
+    var _a3, _b2, _c;
+    const definition = (_a3 = lookupBodySiteDefinition(customSiteMap, canonical)) != null ? _a3 : DEFAULT_BODY_SITE_SNOMED[canonical];
     if (!definition) {
       return void 0;
     }
@@ -4650,10 +4819,10 @@ function renderNominalObject(features) {
   return features.article === "bare" ? features.text : `the ${features.text}`;
 }
 function renderBodySiteObject(features) {
-  var _a;
+  var _a2;
   switch (features.kind) {
     case "locative":
-      return `${(_a = BODY_SITE_LOCATIVE_RENDER_PREPOSITIONS.get(features.relation)) != null ? _a : features.relation} ${renderBodySiteObject(features.target)}`;
+      return `${(_a2 = BODY_SITE_LOCATIVE_RENDER_PREPOSITIONS.get(features.relation)) != null ? _a2 : features.relation} ${renderBodySiteObject(features.target)}`;
     case "partitive":
       return `${features.part.startsWith("both") || features.part.startsWith("bilateral") ? features.part : `the ${features.part}`} of ${renderNominalObject(features.whole)}`;
     case "nominal":
@@ -4689,7 +4858,7 @@ function resolveFeatureCoding(features, customSiteMap) {
   }
 }
 function buildSpatialRelation(features, sourceText, customSiteMap) {
-  var _a;
+  var _a2;
   switch (features.kind) {
     case "locative": {
       const relationCoding = BODY_SITE_SPATIAL_RELATION_CODINGS.get(features.relation);
@@ -4702,7 +4871,7 @@ function buildSpatialRelation(features, sourceText, customSiteMap) {
       };
     }
     case "partitive": {
-      const relationCoding = BODY_SITE_SPATIAL_RELATION_CODINGS.get((_a = features.relationKey) != null ? _a : features.part);
+      const relationCoding = BODY_SITE_SPATIAL_RELATION_CODINGS.get((_a2 = features.relationKey) != null ? _a2 : features.part);
       if (!relationCoding) {
         return void 0;
       }
@@ -4741,7 +4910,7 @@ function inferPreferredPreposition(canonical, features, definition) {
   return void 0;
 }
 function resolveBodySitePhrase(text, customSiteMap, context) {
-  var _a, _b, _c, _d, _e, _f, _g;
+  var _a2, _b, _c, _d, _e, _f, _g;
   const trimmed = text.trim().replace(/\s+/g, " ");
   if (!trimmed) {
     return void 0;
@@ -4751,7 +4920,7 @@ function resolveBodySitePhrase(text, customSiteMap, context) {
   const displaySourceText = contextualCanonical != null ? contextualCanonical : trimmed;
   const displayText = normalizeSiteDisplayText(displaySourceText, customSiteMap);
   const canonical = normalizeBodySiteKey(displayText);
-  const definition = (_e = (_d = (_c = (_b = (_a = lookupBodySiteDefinition(customSiteMap, lookupCanonical)) != null ? _a : contextualCanonical ? lookupBodySiteDefinition(customSiteMap, contextualCanonical) : void 0) != null ? _b : contextualCanonical ? DEFAULT_BODY_SITE_SNOMED[contextualCanonical] : void 0) != null ? _c : DEFAULT_BODY_SITE_SNOMED[lookupCanonical]) != null ? _d : lookupBodySiteDefinition(customSiteMap, canonical)) != null ? _e : DEFAULT_BODY_SITE_SNOMED[canonical];
+  const definition = (_e = (_d = (_c = (_b = (_a2 = lookupBodySiteDefinition(customSiteMap, lookupCanonical)) != null ? _a2 : contextualCanonical ? lookupBodySiteDefinition(customSiteMap, contextualCanonical) : void 0) != null ? _b : contextualCanonical ? DEFAULT_BODY_SITE_SNOMED[contextualCanonical] : void 0) != null ? _c : DEFAULT_BODY_SITE_SNOMED[lookupCanonical]) != null ? _d : lookupBodySiteDefinition(customSiteMap, canonical)) != null ? _e : DEFAULT_BODY_SITE_SNOMED[canonical];
   const coding = buildBodySiteCoding(definition);
   const finalDisplayText = (_f = definition == null ? void 0 : definition.text) != null ? _f : displayText;
   const features = parseBodySiteFeatures(finalDisplayText, coding, customSiteMap);
@@ -4881,7 +5050,7 @@ function getMealTimingGroup(when, options) {
   };
 }
 function inferDailyOccurrenceCount(input, options) {
-  var _a, _b, _c, _d;
+  var _a2, _b, _c, _d;
   if (!(options == null ? void 0 : options.includeTimesPerDaySummary)) {
     return void 0;
   }
@@ -4891,7 +5060,7 @@ function inferDailyOccurrenceCount(input, options) {
   if (input.period !== void 0 || input.periodMax !== void 0 || input.periodUnit !== void 0) {
     return void 0;
   }
-  if (((_b = (_a = input.dayOfWeek) == null ? void 0 : _a.length) != null ? _b : 0) > 0) {
+  if (((_b = (_a2 = input.dayOfWeek) == null ? void 0 : _a2.length) != null ? _b : 0) > 0) {
     return void 0;
   }
   const uniqueWhen2 = uniqueValues((_c = input.when) != null ? _c : []);
@@ -5036,8 +5205,8 @@ var ROUTE_GRAMMAR = {
   }
 };
 function scheduleOf(clause) {
-  var _a;
-  return (_a = clause.schedule) != null ? _a : {};
+  var _a2;
+  return (_a2 = clause.schedule) != null ? _a2 : {};
 }
 function grammarFromRouteText(text) {
   if (!text) {
@@ -5089,16 +5258,16 @@ function grammarFromRouteText(text) {
   return void 0;
 }
 function resolveRouteGrammar(clause) {
-  var _a, _b, _c, _d;
-  const routeCode = (_a = clause.route) == null ? void 0 : _a.code;
+  var _a2, _b, _c, _d;
+  const routeCode = (_a2 = clause.route) == null ? void 0 : _a2.code;
   if (routeCode && ROUTE_GRAMMAR[routeCode]) {
     return (_b = ROUTE_GRAMMAR[routeCode]) != null ? _b : DEFAULT_ROUTE_GRAMMAR;
   }
   return (_d = grammarFromRouteText((_c = clause.route) == null ? void 0 : _c.text)) != null ? _d : DEFAULT_ROUTE_GRAMMAR;
 }
 function resolveMethodVerb(clause, grammar) {
-  var _a, _b;
-  const methodText = (_b = (_a = clause.method) == null ? void 0 : _a.text) == null ? void 0 : _b.trim();
+  var _a2, _b;
+  const methodText = (_b = (_a2 = clause.method) == null ? void 0 : _a2.text) == null ? void 0 : _b.trim();
   if (methodText) {
     return methodText;
   }
@@ -5111,6 +5280,8 @@ function pluralize(unit, value) {
         return "tablet";
       case "cap":
         return "capsule";
+      case "FTU":
+        return "FTU";
       default:
         return unit;
     }
@@ -5118,6 +5289,9 @@ function pluralize(unit, value) {
   if (unit.endsWith(" ribbon")) {
     return unit;
   }
+  if (unit.endsWith(" line")) {
+    return unit;
+  }
   switch (unit) {
     case "tab":
     case "tablet":
@@ -5132,6 +5306,8 @@ function pluralize(unit, value) {
       return "puffs";
     case "patch":
       return "patches";
+    case "ring":
+      return "rings";
     case "drop":
       return "drops";
     case "suppository":
@@ -5146,8 +5322,28 @@ function pluralize(unit, value) {
       return "capfuls";
     case "scoop":
       return "scoops";
+    case "palm":
+      return "palms";
+    case "handprint":
+      return "handprints";
+    case "shot glass":
+      return "shot glasses";
+    case "click":
+      return "clicks";
+    case "vial":
+      return "vials";
+    case "ampule":
+      return "ampules";
+    case "packet":
+      return "packets";
+    case "sachet":
+      return "sachets";
+    case "stick-pack":
+      return "stick-packs";
     case "application":
       return "applications";
+    case "FTU":
+      return "FTU";
     case "fingertip unit":
       return "fingertip units";
     case "finger length":
@@ -5276,12 +5472,12 @@ function describeFrequencyCount(count) {
   return `${stripTrailingZero(count)} times daily`;
 }
 function describeStandaloneOccurrenceCount(schedule) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   const count = schedule == null ? void 0 : schedule.count;
   if (!count || count <= 0) {
     return void 0;
   }
-  if ((schedule == null ? void 0 : schedule.frequency) !== void 0 || (schedule == null ? void 0 : schedule.frequencyMax) !== void 0 || (schedule == null ? void 0 : schedule.period) !== void 0 || (schedule == null ? void 0 : schedule.periodMax) !== void 0 || (schedule == null ? void 0 : schedule.periodUnit) !== void 0 || ((_a = schedule == null ? void 0 : schedule.dayOfWeek) == null ? void 0 : _a.length) || ((_b = schedule == null ? void 0 : schedule.when) == null ? void 0 : _b.length) || ((_c = schedule == null ? void 0 : schedule.timeOfDay) == null ? void 0 : _c.length) || (schedule == null ? void 0 : schedule.duration) !== void 0 || (schedule == null ? void 0 : schedule.durationMax) !== void 0 || (schedule == null ? void 0 : schedule.durationUnit) !== void 0 || (schedule == null ? void 0 : schedule.timingCode)) {
+  if ((schedule == null ? void 0 : schedule.frequency) !== void 0 || (schedule == null ? void 0 : schedule.frequencyMax) !== void 0 || (schedule == null ? void 0 : schedule.period) !== void 0 || (schedule == null ? void 0 : schedule.periodMax) !== void 0 || (schedule == null ? void 0 : schedule.periodUnit) !== void 0 || ((_a2 = schedule == null ? void 0 : schedule.dayOfWeek) == null ? void 0 : _a2.length) || ((_b = schedule == null ? void 0 : schedule.when) == null ? void 0 : _b.length) || ((_c = schedule == null ? void 0 : schedule.timeOfDay) == null ? void 0 : _c.length) || (schedule == null ? void 0 : schedule.duration) !== void 0 || (schedule == null ? void 0 : schedule.durationMax) !== void 0 || (schedule == null ? void 0 : schedule.durationUnit) !== void 0 || (schedule == null ? void 0 : schedule.timingCode)) {
     return void 0;
   }
   switch (count) {
@@ -5373,8 +5569,8 @@ function summarizeMealTimingGroup(group) {
   return `${relationText} ${joinWithAnd(group.meals)}`;
 }
 function collectWhenPhrases(schedule, options) {
-  var _a, _b, _c;
-  const when = (_a = schedule == null ? void 0 : schedule.when) != null ? _a : [];
+  var _a2, _b, _c;
+  const when = (_a2 = schedule == null ? void 0 : schedule.when) != null ? _a2 : [];
   if (!when.length) {
     return [];
   }
@@ -5471,14 +5667,14 @@ function combineFrequencyAndEvents(frequency, events) {
   return { frequency, event: joinWithAnd(events) };
 }
 function buildRoutePhrase(clause, grammar, hasSite) {
-  var _a, _b;
+  var _a2, _b;
   if (typeof grammar.routePhrase === "function") {
     return grammar.routePhrase({ hasSite, clause });
   }
   if (typeof grammar.routePhrase === "string") {
     return grammar.routePhrase;
   }
-  const text = (_b = (_a = clause.route) == null ? void 0 : _a.text) == null ? void 0 : _b.trim();
+  const text = (_b = (_a2 = clause.route) == null ? void 0 : _a2.text) == null ? void 0 : _b.trim();
   if (!text) {
     return void 0;
   }
@@ -5525,11 +5721,11 @@ var ENGLISH_SPATIAL_PREPOSITIONS = {
   under: "under"
 };
 function renderSpatialSiteEnglish(relation, grammar) {
-  var _a, _b, _c, _d;
+  var _a2, _b, _c, _d;
   if (!(relation == null ? void 0 : relation.relationText)) {
     return void 0;
   }
-  const rawTarget = (_b = relation.targetText) != null ? _b : (_a = relation.targetCoding) == null ? void 0 : _a.display;
+  const rawTarget = (_b = relation.targetText) != null ? _b : (_a2 = relation.targetCoding) == null ? void 0 : _a2.display;
   if (!rawTarget) {
     return void 0;
   }
@@ -5557,8 +5753,8 @@ function renderSpatialSiteEnglish(relation, grammar) {
   }
 }
 function formatSite(clause, grammar) {
-  var _a, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n, _o;
-  let text = (_b = (_a = clause.site) == null ? void 0 : _a.text) == null ? void 0 : _b.trim();
+  var _a2, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n, _o;
+  let text = (_b = (_a2 = clause.site) == null ? void 0 : _a2.text) == null ? void 0 : _b.trim();
   if (!text) {
     const spatialSite = renderSpatialSiteEnglish((_c = clause.site) == null ? void 0 : _c.spatialRelation, grammar);
     if (spatialSite) {
@@ -5603,8 +5799,8 @@ function formatSite(clause, grammar) {
   return `${preposition} ${noun}`.trim();
 }
 function describeDayOfWeek(schedule) {
-  var _a, _b;
-  const dayOfWeek = (_a = schedule == null ? void 0 : schedule.dayOfWeek) != null ? _a : [];
+  var _a2, _b;
+  const dayOfWeek = (_a2 = schedule == null ? void 0 : schedule.dayOfWeek) != null ? _a2 : [];
   if (!dayOfWeek.length) {
     return void 0;
   }
@@ -5651,8 +5847,8 @@ function describeDuration(schedule) {
   return `for ${stripTrailingZero(schedule.duration)} ${label(schedule.duration)}`;
 }
 function shouldUseGenericMedicationObject(clause) {
-  var _a, _b;
-  const methodText = (_b = (_a = clause.method) == null ? void 0 : _a.text) == null ? void 0 : _b.trim();
+  var _a2, _b;
+  const methodText = (_b = (_a2 = clause.method) == null ? void 0 : _a2.text) == null ? void 0 : _b.trim();
   switch (methodText) {
     case "Apply sunscreen":
     case "Reapply sunscreen":
@@ -5663,8 +5859,8 @@ function shouldUseGenericMedicationObject(clause) {
   }
 }
 function shouldSuppressRoutePhrase(clause, grammar, verb) {
-  var _a;
-  if (((_a = clause.route) == null ? void 0 : _a.code) !== RouteCode["Oral route"]) {
+  var _a2;
+  if (((_a2 = clause.route) == null ? void 0 : _a2.code) !== RouteCode["Oral route"]) {
     return false;
   }
   if (grammar.routePhrase !== "orally") {
@@ -5679,14 +5875,14 @@ function shouldSuppressRoutePhrase(clause, grammar, verb) {
   }
 }
 function formatShort(clause) {
-  var _a, _b, _c, _d, _e, _f;
+  var _a2, _b, _c, _d, _e, _f;
   const schedule = scheduleOf(clause);
   const parts = [];
   const dosePart = formatDoseShort(clause.dose);
   if (dosePart) {
     parts.push(dosePart);
   }
-  const routeCode = (_a = clause.route) == null ? void 0 : _a.code;
+  const routeCode = (_a2 = clause.route) == null ? void 0 : _a2.code;
   const routeText = (_b = clause.route) == null ? void 0 : _b.text;
   if (routeCode) {
     const short = ROUTE_SHORT[routeCode];
@@ -5744,7 +5940,7 @@ function formatShort(clause) {
   return parts.filter(Boolean).join(" ");
 }
 function formatLong(clause, options) {
-  var _a, _b, _c, _d, _e, _f;
+  var _a2, _b, _c, _d, _e, _f;
   const schedule = scheduleOf(clause);
   const grammar = resolveRouteGrammar(clause);
   const verb = resolveMethodVerb(clause, grammar);
@@ -5753,7 +5949,7 @@ function formatLong(clause, options) {
   const sitePart = formatSite(clause, grammar);
   const routePart = shouldSuppressRoutePhrase(clause, grammar, verb) ? void 0 : buildRoutePhrase(clause, grammar, Boolean(sitePart));
   const standaloneOccurrenceCount = describeStandaloneOccurrenceCount(schedule);
-  const frequencyPart = (_b = (_a = describeFrequency(schedule)) != null ? _a : standaloneOccurrenceCount) != null ? _b : describeFrequencyCount(inferDailyOccurrenceCount(schedule, options));
+  const frequencyPart = (_b = (_a2 = describeFrequency(schedule)) != null ? _a2 : standaloneOccurrenceCount) != null ? _b : describeFrequencyCount(inferDailyOccurrenceCount(schedule, options));
   const eventParts = collectWhenPhrases(schedule, options);
   if ((_c = schedule.timeOfDay) == null ? void 0 : _c.length) {
     const timeStrings = [];
@@ -5830,8 +6026,8 @@ function formatLong(clause, options) {
   return trailingInstructionText ? `${baseSentence} ${trailingInstructionText}` : baseSentence;
 }
 function formatAdditionalInstructions(clause) {
-  var _a, _b, _c, _d, _e, _f;
-  const instructions = (_a = clause.additionalInstructions) != null ? _a : [];
+  var _a2, _b, _c, _d, _e, _f;
+  const instructions = (_a2 = clause.additionalInstructions) != null ? _a2 : [];
   if (!instructions.length) {
     return void 0;
   }
@@ -5966,6 +6162,12 @@ var advice_terminology_default = {
     { surface: "whole", lemma: "whole", partOfSpeech: "modifier", semanticClass: "amount_style" },
     { surface: "thin layer", lemma: "thin layer", partOfSpeech: "noun", semanticClass: "amount_style" },
     { surface: "thin film", lemma: "thin film", partOfSpeech: "noun", semanticClass: "amount_style" },
+    { surface: "thin coat", lemma: "thin layer", partOfSpeech: "noun", semanticClass: "amount_style" },
+    { surface: "thinly", lemma: "thin layer", partOfSpeech: "modifier", semanticClass: "amount_style" },
+    { surface: "thick layer", lemma: "thick layer", partOfSpeech: "noun", semanticClass: "amount_style" },
+    { surface: "thick coat", lemma: "thick layer", partOfSpeech: "noun", semanticClass: "amount_style" },
+    { surface: "thickly", lemma: "thick layer", partOfSpeech: "modifier", semanticClass: "amount_style" },
+    { surface: "gently", lemma: "gently", partOfSpeech: "modifier", semanticClass: "manner_style" },
     { surface: "sparingly", lemma: "sparingly", partOfSpeech: "modifier", semanticClass: "amount_style" },
     { surface: "liberally", lemma: "liberally", partOfSpeech: "modifier", semanticClass: "amount_style" },
     { surface: "slowly", lemma: "slowly", partOfSpeech: "modifier", semanticClass: "manner_style" },
@@ -6020,6 +6222,14 @@ var advice_terminology_default = {
     { surface: "dressing", lemma: "dressing", semanticClass: "material", conceptId: "dressing" },
     { surface: "affected area", lemma: "affected area", semanticClass: "site", conceptId: "affected_area" },
     { surface: "affected areas", lemma: "affected area", semanticClass: "site", conceptId: "affected_area" },
+    { surface: "thinly", lemma: "thin layer", semanticClass: "amount_style", conceptId: "thin_layer" },
+    { surface: "thin layer", lemma: "thin layer", semanticClass: "amount_style", conceptId: "thin_layer" },
+    { surface: "thin film", lemma: "thin layer", semanticClass: "amount_style", conceptId: "thin_layer" },
+    { surface: "thin coat", lemma: "thin layer", semanticClass: "amount_style", conceptId: "thin_layer" },
+    { surface: "thickly", lemma: "thick layer", semanticClass: "amount_style", conceptId: "thick_layer" },
+    { surface: "thick layer", lemma: "thick layer", semanticClass: "amount_style", conceptId: "thick_layer" },
+    { surface: "thick coat", lemma: "thick layer", semanticClass: "amount_style", conceptId: "thick_layer" },
+    { surface: "gently", lemma: "gently", semanticClass: "manner_style", conceptId: "gently" },
     { surface: "slowly", lemma: "slowly", semanticClass: "manner_style", conceptId: "slowly" }
   ]
 };
@@ -6641,7 +6851,124 @@ var advice_rules_default = {
         normalizedTexts: [
           "liberally",
           "apply liberally",
-          "use liberally"
+          "use liberally",
+          "liberal amount",
+          "a liberal amount",
+          "apply liberal amount",
+          "apply a liberal amount",
+          "use liberal amount",
+          "use a liberal amount",
+          "generous amount",
+          "a generous amount",
+          "apply generous amount",
+          "apply a generous amount",
+          "use generous amount",
+          "use a generous amount"
+        ]
+      }
+    },
+    {
+      id: "thin-layer",
+      definition: {
+        code: "420162004",
+        display: "To be spread thinly",
+        text: "Apply thinly",
+        thai: "\u0E17\u0E32\u0E1A\u0E32\u0E07\u0E46"
+      },
+      frames: [
+        {
+          force: "instruction",
+          predicate: { lemma: "apply", semanticClass: "administration" },
+          args: [{ role: "amount", text: "thin layer", conceptId: "thin_layer" }]
+        }
+      ],
+      matcher: {
+        normalizedTexts: [
+          "thinly",
+          "apply thinly",
+          "use thinly",
+          "thin layer",
+          "a thin layer",
+          "apply thin layer",
+          "apply a thin layer",
+          "use thin layer",
+          "use a thin layer",
+          "thin film",
+          "a thin film",
+          "apply thin film",
+          "apply a thin film",
+          "thin coat",
+          "a thin coat",
+          "apply thin coat",
+          "apply a thin coat",
+          "\u0E17\u0E32\u0E1A\u0E32\u0E07\u0E46",
+          "\u0E17\u0E32\u0E1A\u0E32\u0E07 \u0E46",
+          "\u0E1A\u0E32\u0E07\u0E46",
+          "\u0E1A\u0E32\u0E07 \u0E46"
+        ]
+      }
+    },
+    {
+      id: "gently",
+      definition: {
+        code: "418449005",
+        display: "Gently",
+        text: "Apply gently",
+        thai: "\u0E17\u0E32\u0E40\u0E1A\u0E32\u0E46"
+      },
+      frames: [
+        {
+          force: "instruction",
+          predicate: { lemma: "apply", semanticClass: "administration" },
+          args: [{ role: "free", text: "gently", conceptId: "gently" }]
+        }
+      ],
+      matcher: {
+        normalizedTexts: [
+          "gently",
+          "apply gently",
+          "use gently",
+          "\u0E40\u0E1A\u0E32\u0E46",
+          "\u0E40\u0E1A\u0E32 \u0E46",
+          "\u0E17\u0E32\u0E40\u0E1A\u0E32\u0E46",
+          "\u0E17\u0E32\u0E40\u0E1A\u0E32 \u0E46"
+        ]
+      }
+    },
+    {
+      id: "thick-layer",
+      definition: {
+        code: "246703001",
+        display: "Thick",
+        text: "Apply thickly",
+        thai: "\u0E17\u0E32\u0E2B\u0E19\u0E32\u0E46"
+      },
+      frames: [
+        {
+          force: "instruction",
+          predicate: { lemma: "apply", semanticClass: "administration" },
+          args: [{ role: "amount", text: "thick layer", conceptId: "thick_layer" }]
+        }
+      ],
+      matcher: {
+        normalizedTexts: [
+          "thickly",
+          "apply thickly",
+          "use thickly",
+          "thick layer",
+          "a thick layer",
+          "apply thick layer",
+          "apply a thick layer",
+          "use thick layer",
+          "use a thick layer",
+          "thick coat",
+          "a thick coat",
+          "apply thick coat",
+          "apply a thick coat",
+          "\u0E17\u0E32\u0E2B\u0E19\u0E32\u0E46",
+          "\u0E17\u0E32\u0E2B\u0E19\u0E32 \u0E46",
+          "\u0E2B\u0E19\u0E32\u0E46",
+          "\u0E2B\u0E19\u0E32 \u0E46"
         ]
       }
     },
@@ -6879,7 +7206,8 @@ var PER_SLASH_UNITS = /* @__PURE__ */ new Set([
   "minute",
   "minutes"
 ]);
-var COMPACT_DISCRETE_UNITS_PATTERN = /^(tab|tabs|tablet|tablets|cap|caps|capsule|capsules|mg|mcg|ml|g|drops|drop|puff|puffs|spray|sprays|patch|patches)$/i;
+var COMPACT_DISCRETE_UNITS_PATTERN = /^(tab|tabs|tablet|tablets|cap|caps|capsule|capsules|mg|mcg|ml|g|drops|drop|gtt|gtts|eyedrop|eyedrops|puff|puffs|spray|sprays|pump|pumps|ftu|ftus|patch|patches|ring|rings|tube|tubes|bottle|bottles|container|containers|palm|palms|handprint|handprints|click|clicks|vial|vials|ampule|ampules|packet|packets|sachet|sachets|stick-pack|stick-packs|pea-sized)$/i;
+var COMPACT_DISCRETE_UNIT_SUFFIX_PATTERN = /^[A-Za-z-]+$/;
 function classifyLexKind(value) {
   const lower = value.toLowerCase();
   if (/^[0-9]+(?:\.[0-9]+)?$/.test(lower)) {
@@ -7015,7 +7343,7 @@ function splitCompactToken(token) {
   if (/^[0-9]+(?:\.[0-9]+)?$/.test(token)) {
     return [token];
   }
-  const compactTimesWord = token.match(/^([0-9]+(?:\.[0-9]+)?[x*])([A-Za-z]+)$/i);
+  const compactTimesWord = token.match(/^([0-9]+(?:\.[0-9]+)?[x*])([A-Za-z-]+)$/i);
   if (compactTimesWord) {
     return [compactTimesWord[1], compactTimesWord[2]];
   }
@@ -7026,11 +7354,11 @@ function splitCompactToken(token) {
   if (/^[A-Za-z]+$/.test(token)) {
     return [token];
   }
-  const qRange = token.match(/^q([0-9]+(?:\.[0-9]+)?)-([0-9]+(?:\.[0-9]+)?)([A-Za-z]+)$/i);
+  const qRange = token.match(/^q([0-9]+(?:\.[0-9]+)?)-([0-9]+(?:\.[0-9]+)?)([A-Za-z-]+)$/i);
   if (qRange) {
     return [token.charAt(0), `${qRange[1]}-${qRange[2]}`, qRange[3]];
   }
-  const match = token.match(/^([0-9]+(?:\.[0-9]+)?)([A-Za-z]+)$/);
+  const match = token.match(/^([0-9]+(?:\.[0-9]+)?)([A-Za-z-]+)$/);
   if (match) {
     const [, numberPart, suffix] = match;
     if (/^(st|nd|rd|th)$/i.test(suffix)) {
@@ -7207,9 +7535,9 @@ function pushTextToken(output, surface, input) {
     }
   }
   const compactDiscrete = surface.original.match(
-    /^([0-9]+(?:\.[0-9]+)?)([A-Za-z]+)$/
+    /^([0-9]+(?:\.[0-9]+)?)([A-Za-z-]+)$/
   );
-  if (compactDiscrete && COMPACT_DISCRETE_UNITS_PATTERN.test(compactDiscrete[2])) {
+  if (compactDiscrete && COMPACT_DISCRETE_UNIT_SUFFIX_PATTERN.test(compactDiscrete[2]) && COMPACT_DISCRETE_UNITS_PATTERN.test(compactDiscrete[2])) {
     pushSplitParts(output, surface, [compactDiscrete[1], compactDiscrete[2]], input);
     return;
   }
@@ -7428,9 +7756,11 @@ function cleanFreeText(value) {
   return collapseWhitespace(value.slice(start, end));
 }
 function createDefinitionFromSource(source) {
+  var _a2;
+  const system = ((_a2 = source.system) == null ? void 0 : _a2.trim()) || SNOMED_SYSTEM4;
   return {
     coding: {
-      system: SNOMED_SYSTEM4,
+      system,
       code: source.code,
       display: source.display
     },
@@ -7734,9 +8064,9 @@ function matchesAdviceMatcher(frames, normalizedText, matcher) {
   return false;
 }
 function findRuleByCoding(system, code) {
-  var _a, _b;
+  var _a2, _b;
   for (const rule of ADDITIONAL_INSTRUCTION_RULES) {
-    if (((_a = rule.definition.coding) == null ? void 0 : _a.system) !== system) {
+    if (((_a2 = rule.definition.coding) == null ? void 0 : _a2.system) !== system) {
       continue;
     }
     if (((_b = rule.definition.coding) == null ? void 0 : _b.code) !== code) {
@@ -7849,8 +8179,8 @@ function findVerbLexeme(word) {
   return findNormalizedLexeme(word, "verb");
 }
 function findVerbLemma(word) {
-  var _a;
-  return (_a = findVerbLexeme(word)) == null ? void 0 : _a.lemma;
+  var _a2;
+  return (_a2 = findVerbLexeme(word)) == null ? void 0 : _a2.lemma;
 }
 function findModalLexeme(word) {
   const entry = findNormalizedLexeme(word, "modifier");
@@ -7962,7 +8292,7 @@ function parseLeadingClauseFeatures(words) {
   };
 }
 function deriveClauseForce(sequenceCount, context, predicateLemma, predicateSemanticClass, polarity, modality) {
-  var _a;
+  var _a2;
   if (sequenceCount > 1) {
     return "sequence" /* Sequence */;
   }
@@ -7995,7 +8325,7 @@ function deriveClauseForce(sequenceCount, context, predicateLemma, predicateSema
     default:
       break;
   }
-  return (_a = context.defaultForce) != null ? _a : "instruction" /* Instruction */;
+  return (_a2 = context.defaultForce) != null ? _a2 : "instruction" /* Instruction */;
 }
 function containsNegatedVerb(words, lemma) {
   for (let index = 0; index < words.length; index += 1) {
@@ -8264,11 +8594,11 @@ function skipLeadingNoise(words) {
   return cursor;
 }
 function createDefaultForce(sequenceCount, sequenceIndex, context) {
-  var _a;
+  var _a2;
   if (sequenceCount > 1 || sequenceIndex > 0) {
     return "sequence" /* Sequence */;
   }
-  return (_a = context.defaultForce) != null ? _a : "instruction" /* Instruction */;
+  return (_a2 = context.defaultForce) != null ? _a2 : "instruction" /* Instruction */;
 }
 function tryParseRelationInstruction(sourceText, span, context, sequenceIndex, sequenceCount) {
   const words = normalizeWords(sourceText);
@@ -8633,7 +8963,7 @@ function tryParseClauseInstruction(sourceText, span, context, sequenceIndex, seq
   return frames;
 }
 function parseSequenceFrames(sourceText, span, context) {
-  var _a, _b, _c, _d, _e;
+  var _a2, _b, _c, _d, _e;
   const sequenceSegments = splitSequenceSegments(sourceText, span);
   if (!sequenceSegments.length) {
     return [];
@@ -8641,7 +8971,7 @@ function parseSequenceFrames(sourceText, span, context) {
   const frames = [];
   for (let index = 0; index < sequenceSegments.length; index++) {
     const segment = sequenceSegments[index];
-    const parsed = (_e = (_d = (_c = (_b = (_a = tryParseRelationInstruction(segment.text, segment.range, context, index, sequenceSegments.length)) != null ? _a : tryParseImplicitConceptInstruction(segment.text, segment.range, context, index, sequenceSegments.length)) != null ? _b : tryParseStyleInstruction(segment.text, segment.range, context, index, sequenceSegments.length)) != null ? _c : tryParseNoObjectInstruction(segment.text, segment.range, index, sequenceSegments.length)) != null ? _d : tryParseEllipticalEffectInstruction(
+    const parsed = (_e = (_d = (_c = (_b = (_a2 = tryParseRelationInstruction(segment.text, segment.range, context, index, sequenceSegments.length)) != null ? _a2 : tryParseImplicitConceptInstruction(segment.text, segment.range, context, index, sequenceSegments.length)) != null ? _b : tryParseStyleInstruction(segment.text, segment.range, context, index, sequenceSegments.length)) != null ? _c : tryParseNoObjectInstruction(segment.text, segment.range, index, sequenceSegments.length)) != null ? _d : tryParseEllipticalEffectInstruction(
       segment.text,
       segment.range,
       context,
@@ -8767,9 +9097,9 @@ function realizeAdviceFramesText(frames) {
   return realized ? capitalizeSentence(realized) : void 0;
 }
 function parseAdditionalInstructions(sourceText, span, context) {
-  var _a, _b, _c, _d, _e;
+  var _a2, _b, _c, _d, _e;
   const effectiveContext = {
-    defaultPredicate: (_a = context == null ? void 0 : context.defaultPredicate) != null ? _a : DEFAULT_INSTRUCTION_CONTEXT.defaultPredicate,
+    defaultPredicate: (_a2 = context == null ? void 0 : context.defaultPredicate) != null ? _a2 : DEFAULT_INSTRUCTION_CONTEXT.defaultPredicate,
     defaultForce: (_b = context == null ? void 0 : context.defaultForce) != null ? _b : DEFAULT_INSTRUCTION_CONTEXT.defaultForce,
     allowFreeTextFallback: (_c = context == null ? void 0 : context.allowFreeTextFallback) != null ? _c : DEFAULT_INSTRUCTION_CONTEXT.allowFreeTextFallback
   };
@@ -8803,16 +9133,16 @@ function parseAdditionalInstructions(sourceText, span, context) {
   return instructions;
 }
 function findAdditionalInstructionDefinitionByCoding(system, code) {
-  var _a;
-  return (_a = findRuleByCoding(system, code)) == null ? void 0 : _a.definition;
+  var _a2;
+  return (_a2 = findRuleByCoding(system, code)) == null ? void 0 : _a2.definition;
 }
 function buildAdditionalInstructionFramesFromCoding(system, code, sourceText, span) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   const rule = findRuleByCoding(system, code);
   if (!rule) {
     return void 0;
   }
-  const resolvedText = (_c = (_b = sourceText != null ? sourceText : rule.definition.text) != null ? _b : (_a = rule.definition.coding) == null ? void 0 : _a.display) != null ? _c : "";
+  const resolvedText = (_c = (_b = sourceText != null ? sourceText : rule.definition.text) != null ? _b : (_a2 = rule.definition.coding) == null ? void 0 : _a2.display) != null ? _c : "";
   const resolvedSpan = span != null ? span : { start: 0, end: resolvedText.length };
   return instantiateTemplateFrames(rule.frames, resolvedText, resolvedSpan);
 }
@@ -8876,12 +9206,12 @@ function pluralizeBodySiteText(text) {
   return `${normalized}s`;
 }
 function toBodySiteCode(coding) {
-  var _a;
+  var _a2;
   if (!(coding == null ? void 0 : coding.code)) {
     return void 0;
   }
   return {
-    system: (_a = coding.system) != null ? _a : SNOMED_SYSTEM,
+    system: (_a2 = coding.system) != null ? _a2 : SNOMED_SYSTEM,
     code: coding.code,
     display: coding.display,
     i18n: "i18n" in coding ? coding.i18n : void 0
@@ -8901,11 +9231,11 @@ function resultFromResolved(resolved, matchedText, score) {
   };
 }
 function bodySiteLookupRequest(input, resolved, options) {
-  var _a, _b;
+  var _a2, _b;
   const normalized = normalizeBodySiteKey(input);
   return {
     originalText: input,
-    text: (_a = resolved == null ? void 0 : resolved.displayText) != null ? _a : input.trim(),
+    text: (_a2 = resolved == null ? void 0 : resolved.displayText) != null ? _a2 : input.trim(),
     normalized,
     canonical: (_b = resolved == null ? void 0 : resolved.canonical) != null ? _b : normalized,
     bodySiteContext: options == null ? void 0 : options.bodySiteContext,
@@ -8913,18 +9243,18 @@ function bodySiteLookupRequest(input, resolved, options) {
   };
 }
 function applyResolverDefinition(result, definition) {
-  var _a, _b;
+  var _a2, _b;
   return __spreadProps(__spreadValues({}, result), {
-    text: (_a = definition.text) != null ? _a : result.text,
+    text: (_a2 = definition.text) != null ? _a2 : result.text,
     coding: toBodySiteCode(definition.coding),
     spatialRelation: (_b = definition.spatialRelation) != null ? _b : result.spatialRelation,
     definition
   });
 }
 function resultFromResolverDefinition(input, definition) {
-  var _a;
+  var _a2;
   const normalized = normalizeBodySiteKey(input);
-  const text = (_a = definition.text) != null ? _a : normalized;
+  const text = (_a2 = definition.text) != null ? _a2 : normalized;
   return {
     text,
     canonical: normalizeBodySiteKey(text),
@@ -8980,12 +9310,12 @@ function addCandidate(candidates, phrase, definition) {
   candidates.push({ phrase: normalized, definition });
 }
 function addDefinitionCandidates(candidates, definition) {
-  var _a;
+  var _a2;
   if (!definition) {
     return;
   }
   addCandidate(candidates, definition.text, definition);
-  for (const alias of (_a = definition.aliases) != null ? _a : []) {
+  for (const alias of (_a2 = definition.aliases) != null ? _a2 : []) {
     addCandidate(candidates, alias, definition);
   }
 }
@@ -9006,21 +9336,21 @@ function collectBodySiteCandidates(siteCodeMap) {
   return candidates;
 }
 function codeFromInput(input, options) {
-  var _a;
+  var _a2;
   if (typeof input === "string") {
     const normalized = input.trim();
-    return normalized ? { code: normalized, system: (_a = options == null ? void 0 : options.system) != null ? _a : SNOMED_SYSTEM } : void 0;
+    return normalized ? { code: normalized, system: (_a2 = options == null ? void 0 : options.system) != null ? _a2 : SNOMED_SYSTEM } : void 0;
   }
   return toBodySiteCode(input);
 }
 function bodySiteCodeFromInput(input, options) {
-  var _a, _b;
+  var _a2, _b;
   const coding = codeFromInput(input, options);
   const shouldParsePostcoordination = (options == null ? void 0 : options.postcoordination) !== false && (options == null ? void 0 : options.parsePostcoordination) !== false;
   const parsedTopographicalModifier = shouldParsePostcoordination ? parseSnomedBodySiteTopographicalModifierPostcoordinationCode(coding == null ? void 0 : coding.code) : void 0;
   if (parsedTopographicalModifier) {
     return {
-      system: (_a = coding == null ? void 0 : coding.system) != null ? _a : SNOMED_SYSTEM,
+      system: (_a2 = coding == null ? void 0 : coding.system) != null ? _a2 : SNOMED_SYSTEM,
       code: parsedTopographicalModifier.siteCode
     };
   }
@@ -9048,24 +9378,24 @@ function parsedPostcoordinationForInput(input, options) {
   };
 }
 function findBodySiteTextByCode(coding, siteCodeMap) {
-  var _a;
+  var _a2;
   for (const candidate of collectBodySiteCandidates(siteCodeMap)) {
-    if (codeMatches(coding, (_a = candidate.definition) == null ? void 0 : _a.coding)) {
+    if (codeMatches(coding, (_a2 = candidate.definition) == null ? void 0 : _a2.coding)) {
       return definitionText(candidate.phrase, candidate.definition);
     }
   }
   return void 0;
 }
 function definitionText(phrase, definition) {
-  var _a;
-  return (_a = definition == null ? void 0 : definition.text) != null ? _a : normalizeBodySiteKey(phrase);
+  var _a2;
+  return (_a2 = definition == null ? void 0 : definition.text) != null ? _a2 : normalizeBodySiteKey(phrase);
 }
 function codeMatches(left, right) {
-  var _a, _b;
+  var _a2, _b;
   if (!(right == null ? void 0 : right.code)) {
     return false;
   }
-  const leftSystem = (_a = left.system) != null ? _a : SNOMED_SYSTEM;
+  const leftSystem = (_a2 = left.system) != null ? _a2 : SNOMED_SYSTEM;
   const rightSystem = (_b = right.system) != null ? _b : SNOMED_SYSTEM;
   return left.code === right.code && leftSystem === rightSystem;
 }
@@ -9147,11 +9477,11 @@ function scoreCandidate(query, candidate) {
   return 0;
 }
 function spatialRelationKey(relation) {
-  var _a, _b, _c, _d, _e;
+  var _a2, _b, _c, _d, _e;
   if (!relation) {
     return "";
   }
-  const relationCode = (_b = (_a = relation.relationCoding) == null ? void 0 : _a.code) != null ? _b : "";
+  const relationCode = (_b = (_a2 = relation.relationCoding) == null ? void 0 : _a2.code) != null ? _b : "";
   const targetCode = (_d = (_c = relation.targetCoding) == null ? void 0 : _c.code) != null ? _d : "";
   return [
     relation.relationText,
@@ -9161,9 +9491,9 @@ function spatialRelationKey(relation) {
   ].join("|");
 }
 function resultKey(result) {
-  var _a, _b;
+  var _a2, _b;
   const relation = spatialRelationKey(result.spatialRelation);
-  if ((_a = result.coding) == null ? void 0 : _a.code) {
+  if ((_a2 = result.coding) == null ? void 0 : _a2.code) {
     return `${(_b = result.coding.system) != null ? _b : SNOMED_SYSTEM}|${result.coding.code}|${relation}`;
   }
   return `${result.canonical}|${relation}`;
@@ -9194,16 +9524,16 @@ function sortedSetValues(values) {
   return Array.from(values).sort((left, right) => left.localeCompare(right));
 }
 function canBuildTopographicalModifierPostcoordination(relation) {
-  var _a, _b;
-  if (!((_a = relation == null ? void 0 : relation.relationCoding) == null ? void 0 : _a.code) || !((_b = relation.targetCoding) == null ? void 0 : _b.code)) {
+  var _a2, _b;
+  if (!((_a2 = relation == null ? void 0 : relation.relationCoding) == null ? void 0 : _a2.code) || !((_b = relation.targetCoding) == null ? void 0 : _b.code)) {
     return false;
   }
   return POSTCOORDINATABLE_RELATION_TEXTS.has(normalizeBodySiteKey(relation.relationText)) || POSTCOORDINATABLE_RELATION_CODES.has(relation.relationCoding.code);
 }
 function buildSpatialRelationDisplayText(relation) {
-  var _a;
+  var _a2;
   const relationText = normalizeBodySiteKey(relation.relationText);
-  const targetText = normalizeBodySiteKey((_a = relation.targetText) != null ? _a : "");
+  const targetText = normalizeBodySiteKey((_a2 = relation.targetText) != null ? _a2 : "");
   if (!relationText || !targetText) {
     return void 0;
   }
@@ -9224,14 +9554,14 @@ function buildSpatialRelationDisplayText(relation) {
   }
 }
 function buildBodySiteTopographicalModifierCoding(relation, display, options) {
-  var _a, _b;
+  var _a2, _b;
   if ((options == null ? void 0 : options.postcoordination) === false) {
     return void 0;
   }
   if (!canBuildTopographicalModifierPostcoordination(relation)) {
     return void 0;
   }
-  const targetSystem = (_a = relation.targetCoding.system) != null ? _a : SNOMED_SYSTEM;
+  const targetSystem = (_a2 = relation.targetCoding.system) != null ? _a2 : SNOMED_SYSTEM;
   const relationSystem = (_b = relation.relationCoding.system) != null ? _b : SNOMED_SYSTEM;
   if (targetSystem !== SNOMED_SYSTEM || relationSystem !== SNOMED_SYSTEM) {
     return void 0;
@@ -9264,12 +9594,12 @@ function lookupBodySiteAsync(input, options) {
   });
 }
 function getBodySiteCode(input, options) {
-  var _a;
+  var _a2;
   const resolved = lookupBodySite(input, options);
   if (!resolved) {
     return void 0;
   }
-  return (_a = resolved.coding) != null ? _a : buildBodySiteTopographicalModifierCoding(
+  return (_a2 = resolved.coding) != null ? _a2 : buildBodySiteTopographicalModifierCoding(
     resolved.spatialRelation,
     resolved.text,
     options
@@ -9277,12 +9607,12 @@ function getBodySiteCode(input, options) {
 }
 function getBodySiteCodeAsync(input, options) {
   return __async(this, null, function* () {
-    var _a;
+    var _a2;
     const resolved = yield lookupBodySiteAsync(input, options);
     if (!resolved) {
       return void 0;
     }
-    return (_a = resolved.coding) != null ? _a : buildBodySiteTopographicalModifierCoding(
+    return (_a2 = resolved.coding) != null ? _a2 : buildBodySiteTopographicalModifierCoding(
       resolved.spatialRelation,
       resolved.text,
       options
@@ -9290,7 +9620,7 @@ function getBodySiteCodeAsync(input, options) {
   });
 }
 function getBodySiteText(input, options) {
-  var _a;
+  var _a2;
   const originalCoding = codeFromInput(input, options);
   const coding = bodySiteCodeFromInput(input, options);
   if (!coding) {
@@ -9316,7 +9646,7 @@ function getBodySiteText(input, options) {
   if (!text && parsed.laterality) {
     const baseText = findBodySiteTextByCode(
       {
-        system: (_a = originalCoding == null ? void 0 : originalCoding.system) != null ? _a : SNOMED_SYSTEM,
+        system: (_a2 = originalCoding == null ? void 0 : originalCoding.system) != null ? _a2 : SNOMED_SYSTEM,
         code: parsed.laterality.siteCode
       },
       options == null ? void 0 : options.siteCodeMap
@@ -9363,12 +9693,12 @@ function getBodySiteTextAsync(input, options) {
   });
 }
 function suggestBodySites(input, options) {
-  var _a;
+  var _a2;
   const query = normalizeBodySiteKey(input);
   if (!query) {
     return [];
   }
-  const limit = (_a = options == null ? void 0 : options.limit) != null ? _a : 10;
+  const limit = (_a2 = options == null ? void 0 : options.limit) != null ? _a2 : 10;
   if (limit <= 0) {
     return [];
   }
@@ -9397,8 +9727,8 @@ function suggestBodySiteText(input, options) {
   return uniqueText(suggestBodySites(input, options));
 }
 function listSupportedBodySiteText(options) {
-  var _a;
-  const limit = (_a = options == null ? void 0 : options.limit) != null ? _a : Number.POSITIVE_INFINITY;
+  var _a2;
+  const limit = (_a2 = options == null ? void 0 : options.limit) != null ? _a2 : Number.POSITIVE_INFINITY;
   if (limit <= 0) {
     return [];
   }
@@ -9469,43 +9799,43 @@ var ParserState = class {
     return this.clause;
   }
   get dose() {
-    var _a;
-    return (_a = this.clause.dose) == null ? void 0 : _a.value;
+    var _a2;
+    return (_a2 = this.clause.dose) == null ? void 0 : _a2.value;
   }
   set dose(value) {
     this.ensureDose().value = value;
   }
   get doseRange() {
-    var _a;
-    return (_a = this.clause.dose) == null ? void 0 : _a.range;
+    var _a2;
+    return (_a2 = this.clause.dose) == null ? void 0 : _a2.range;
   }
   set doseRange(value) {
     this.ensureDose().range = value;
   }
   get unit() {
-    var _a;
-    return (_a = this.clause.dose) == null ? void 0 : _a.unit;
+    var _a2;
+    return (_a2 = this.clause.dose) == null ? void 0 : _a2.unit;
   }
   set unit(value) {
     this.ensureDose().unit = value;
   }
   get routeCode() {
-    var _a;
-    return (_a = this.clause.route) == null ? void 0 : _a.code;
+    var _a2;
+    return (_a2 = this.clause.route) == null ? void 0 : _a2.code;
   }
   set routeCode(value) {
     this.ensureRoute().code = value;
   }
   get routeText() {
-    var _a;
-    return (_a = this.clause.route) == null ? void 0 : _a.text;
+    var _a2;
+    return (_a2 = this.clause.route) == null ? void 0 : _a2.text;
   }
   set routeText(value) {
     this.ensureRoute().text = value;
   }
   get methodText() {
-    var _a;
-    return (_a = this.clause.method) == null ? void 0 : _a.text;
+    var _a2;
+    return (_a2 = this.clause.method) == null ? void 0 : _a2.text;
   }
   set methodText(value) {
     if (value === void 0) {
@@ -9518,8 +9848,8 @@ var ParserState = class {
     this.ensureMethod().text = value;
   }
   get methodTextElement() {
-    var _a;
-    return (_a = this.clause.method) == null ? void 0 : _a._text;
+    var _a2;
+    return (_a2 = this.clause.method) == null ? void 0 : _a2._text;
   }
   set methodTextElement(value) {
     if (value === void 0) {
@@ -9532,8 +9862,8 @@ var ParserState = class {
     this.ensureMethod()._text = clonePrimitiveElement(value);
   }
   get methodCoding() {
-    var _a;
-    return (_a = this.clause.method) == null ? void 0 : _a.coding;
+    var _a2;
+    return (_a2 = this.clause.method) == null ? void 0 : _a2.coding;
   }
   set methodCoding(value) {
     if (value === void 0) {
@@ -9552,64 +9882,64 @@ var ParserState = class {
     } : void 0;
   }
   get count() {
-    var _a;
-    return (_a = this.clause.schedule) == null ? void 0 : _a.count;
+    var _a2;
+    return (_a2 = this.clause.schedule) == null ? void 0 : _a2.count;
   }
   set count(value) {
     this.ensureSchedule().count = value;
   }
   get duration() {
-    var _a;
-    return (_a = this.clause.schedule) == null ? void 0 : _a.duration;
+    var _a2;
+    return (_a2 = this.clause.schedule) == null ? void 0 : _a2.duration;
   }
   set duration(value) {
     this.ensureSchedule().duration = value;
   }
   get durationMax() {
-    var _a;
-    return (_a = this.clause.schedule) == null ? void 0 : _a.durationMax;
+    var _a2;
+    return (_a2 = this.clause.schedule) == null ? void 0 : _a2.durationMax;
   }
   set durationMax(value) {
     this.ensureSchedule().durationMax = value;
   }
   get durationUnit() {
-    var _a;
-    return (_a = this.clause.schedule) == null ? void 0 : _a.durationUnit;
+    var _a2;
+    return (_a2 = this.clause.schedule) == null ? void 0 : _a2.durationUnit;
   }
   set durationUnit(value) {
     this.ensureSchedule().durationUnit = value;
   }
   get frequency() {
-    var _a;
-    return (_a = this.clause.schedule) == null ? void 0 : _a.frequency;
+    var _a2;
+    return (_a2 = this.clause.schedule) == null ? void 0 : _a2.frequency;
   }
   set frequency(value) {
     this.ensureSchedule().frequency = value;
   }
   get frequencyMax() {
-    var _a;
-    return (_a = this.clause.schedule) == null ? void 0 : _a.frequencyMax;
+    var _a2;
+    return (_a2 = this.clause.schedule) == null ? void 0 : _a2.frequencyMax;
   }
   set frequencyMax(value) {
     this.ensureSchedule().frequencyMax = value;
   }
   get period() {
-    var _a;
-    return (_a = this.clause.schedule) == null ? void 0 : _a.period;
+    var _a2;
+    return (_a2 = this.clause.schedule) == null ? void 0 : _a2.period;
   }
   set period(value) {
     this.ensureSchedule().period = value;
   }
   get periodMax() {
-    var _a;
-    return (_a = this.clause.schedule) == null ? void 0 : _a.periodMax;
+    var _a2;
+    return (_a2 = this.clause.schedule) == null ? void 0 : _a2.periodMax;
   }
   set periodMax(value) {
     this.ensureSchedule().periodMax = value;
   }
   get periodUnit() {
-    var _a;
-    return (_a = this.clause.schedule) == null ? void 0 : _a.periodUnit;
+    var _a2;
+    return (_a2 = this.clause.schedule) == null ? void 0 : _a2.periodUnit;
   }
   set periodUnit(value) {
     this.ensureSchedule().periodUnit = value;
@@ -9629,22 +9959,22 @@ var ParserState = class {
     return schedule.when;
   }
   get timeOfDay() {
-    var _a;
-    return (_a = this.clause.schedule) == null ? void 0 : _a.timeOfDay;
+    var _a2;
+    return (_a2 = this.clause.schedule) == null ? void 0 : _a2.timeOfDay;
   }
   set timeOfDay(value) {
     this.ensureSchedule().timeOfDay = value;
   }
   get timingCode() {
-    var _a;
-    return (_a = this.clause.schedule) == null ? void 0 : _a.timingCode;
+    var _a2;
+    return (_a2 = this.clause.schedule) == null ? void 0 : _a2.timingCode;
   }
   set timingCode(value) {
     this.ensureSchedule().timingCode = value;
   }
   get asNeeded() {
-    var _a;
-    return (_a = this.clause.prn) == null ? void 0 : _a.enabled;
+    var _a2;
+    return (_a2 = this.clause.prn) == null ? void 0 : _a2.enabled;
   }
   set asNeeded(value) {
     if (value === void 0) {
@@ -9654,13 +9984,13 @@ var ParserState = class {
     this.ensurePrn().enabled = value;
   }
   get asNeededReason() {
-    var _a, _b;
-    return (_b = (_a = this.clause.prn) == null ? void 0 : _a.reason) == null ? void 0 : _b.text;
+    var _a2, _b;
+    return (_b = (_a2 = this.clause.prn) == null ? void 0 : _a2.reason) == null ? void 0 : _b.text;
   }
   set asNeededReason(value) {
-    var _a, _b;
+    var _a2, _b;
     if (value === void 0) {
-      if ((_a = this.clause.prn) == null ? void 0 : _a.reason) {
+      if ((_a2 = this.clause.prn) == null ? void 0 : _a2.reason) {
         delete this.clause.prn.reason.text;
         this.cleanupPrn();
       }
@@ -9676,13 +10006,13 @@ var ParserState = class {
     prn.reason.text = value;
   }
   get asNeededReasons() {
-    var _a;
-    return (_a = this.clause.prn) == null ? void 0 : _a.reasons;
+    var _a2;
+    return (_a2 = this.clause.prn) == null ? void 0 : _a2.reasons;
   }
   set asNeededReasons(value) {
-    var _a, _b;
+    var _a2, _b;
     if (!value || !value.length) {
-      if ((_a = this.clause.prn) == null ? void 0 : _a.reasons) {
+      if ((_a2 = this.clause.prn) == null ? void 0 : _a2.reasons) {
         delete this.clause.prn.reasons;
         this.cleanupPrn();
       }
@@ -9710,13 +10040,13 @@ var ParserState = class {
     prn.reasons = reasons;
   }
   get asNeededReasonCoding() {
-    var _a, _b;
-    return (_b = (_a = this.clause.prn) == null ? void 0 : _a.reason) == null ? void 0 : _b.coding;
+    var _a2, _b;
+    return (_b = (_a2 = this.clause.prn) == null ? void 0 : _a2.reason) == null ? void 0 : _b.coding;
   }
   set asNeededReasonCoding(value) {
-    var _a, _b;
+    var _a2, _b;
     if (value === void 0) {
-      if ((_a = this.clause.prn) == null ? void 0 : _a.reason) {
+      if ((_a2 = this.clause.prn) == null ? void 0 : _a2.reason) {
         delete this.clause.prn.reason.coding;
         this.cleanupPrn();
       }
@@ -9739,22 +10069,22 @@ var ParserState = class {
     } : void 0;
   }
   get siteText() {
-    var _a;
-    return (_a = this.clause.site) == null ? void 0 : _a.text;
+    var _a2;
+    return (_a2 = this.clause.site) == null ? void 0 : _a2.text;
   }
   set siteText(value) {
     this.ensureSite().text = value;
   }
   get siteSource() {
-    var _a;
-    return (_a = this.clause.site) == null ? void 0 : _a.source;
+    var _a2;
+    return (_a2 = this.clause.site) == null ? void 0 : _a2.source;
   }
   set siteSource(value) {
     this.ensureSite().source = value;
   }
   get siteCoding() {
-    var _a;
-    return (_a = this.clause.site) == null ? void 0 : _a.coding;
+    var _a2;
+    return (_a2 = this.clause.site) == null ? void 0 : _a2.coding;
   }
   set siteCoding(value) {
     if (value === void 0) {
@@ -9772,8 +10102,8 @@ var ParserState = class {
     } : void 0;
   }
   get siteSpatialRelation() {
-    var _a;
-    return (_a = this.clause.site) == null ? void 0 : _a.spatialRelation;
+    var _a2;
+    return (_a2 = this.clause.site) == null ? void 0 : _a2.spatialRelation;
   }
   set siteSpatialRelation(value) {
     if (value === void 0) {
@@ -9855,7 +10185,7 @@ var ParserState = class {
     return this.clause.prn;
   }
   cleanupPrn() {
-    var _a;
+    var _a2;
     const prn = this.clause.prn;
     if (!prn) {
       return;
@@ -9863,7 +10193,7 @@ var ParserState = class {
     if (prn.reason && prn.reason.text === void 0 && prn.reason.coding === void 0) {
       delete prn.reason;
     }
-    if (((_a = prn.reasons) == null ? void 0 : _a.length) === 0) {
+    if (((_a2 = prn.reasons) == null ? void 0 : _a2.length) === 0) {
       delete prn.reasons;
     }
     if (prn.enabled === void 0 && prn.reason === void 0 && prn.reasons === void 0) {
@@ -9918,8 +10248,8 @@ function createEmptyCanonicalClause(rawText) {
   };
 }
 function selectFirstCodingWithCode(concept) {
-  var _a;
-  if (!((_a = concept == null ? void 0 : concept.coding) == null ? void 0 : _a.length)) {
+  var _a2;
+  if (!((_a2 = concept == null ? void 0 : concept.coding) == null ? void 0 : _a2.length)) {
     return void 0;
   }
   for (const coding of concept.coding) {
@@ -9930,8 +10260,8 @@ function selectFirstCodingWithCode(concept) {
   return void 0;
 }
 function selectPreferredSiteCoding(site) {
-  var _a;
-  if (!((_a = site == null ? void 0 : site.coding) == null ? void 0 : _a.length)) {
+  var _a2;
+  if (!((_a2 = site == null ? void 0 : site.coding) == null ? void 0 : _a2.length)) {
     return void 0;
   }
   for (const coding of site.coding) {
@@ -9942,7 +10272,7 @@ function selectPreferredSiteCoding(site) {
   return selectFirstCodingWithCode(site);
 }
 function selectCanonicalSiteCoding(site, options) {
-  var _a;
+  var _a2;
   if ((options == null ? void 0 : options.bodySitePostcoordination) === false) {
     return site == null ? void 0 : site.coding;
   }
@@ -9951,16 +10281,16 @@ function selectCanonicalSiteCoding(site, options) {
     site == null ? void 0 : site.text,
     { postcoordination: true }
   );
-  return (options == null ? void 0 : options.bodySitePostcoordination) === true ? postcoordinated != null ? postcoordinated : site == null ? void 0 : site.coding : (_a = site == null ? void 0 : site.coding) != null ? _a : postcoordinated;
+  return (options == null ? void 0 : options.bodySitePostcoordination) === true ? postcoordinated != null ? postcoordinated : site == null ? void 0 : site.coding : (_a2 = site == null ? void 0 : site.coding) != null ? _a2 : postcoordinated;
 }
 function buildSiteCodingArray(siteCoding) {
-  var _a;
+  var _a2;
   if (!(siteCoding == null ? void 0 : siteCoding.code)) {
     return void 0;
   }
   return [
     {
-      system: (_a = siteCoding.system) != null ? _a : SNOMED_SYSTEM5,
+      system: (_a2 = siteCoding.system) != null ? _a2 : SNOMED_SYSTEM5,
       code: siteCoding.code,
       display: siteCoding.display
     }
@@ -9982,12 +10312,12 @@ function lowerFirst(value) {
   return trimmed ? trimmed.charAt(0).toLowerCase() + trimmed.slice(1) : void 0;
 }
 function getSpatialPrnReasonSiteText(spatialRelation) {
-  var _a;
+  var _a2;
   const sourceText = lowerFirst(spatialRelation == null ? void 0 : spatialRelation.sourceText);
   if (sourceText) {
     return sourceText;
   }
-  const targetText = (_a = lowerFirst(spatialRelation == null ? void 0 : spatialRelation.targetText)) != null ? _a : (spatialRelation == null ? void 0 : spatialRelation.targetCoding) ? getBodySiteText(spatialRelation.targetCoding) : void 0;
+  const targetText = (_a2 = lowerFirst(spatialRelation == null ? void 0 : spatialRelation.targetText)) != null ? _a2 : (spatialRelation == null ? void 0 : spatialRelation.targetCoding) ? getBodySiteText(spatialRelation.targetCoding) : void 0;
   if (!targetText) {
     return void 0;
   }
@@ -10024,7 +10354,7 @@ function getSpatialPrnReasonSiteText(spatialRelation) {
   }
 }
 function getFallbackPrnReasonText(concept) {
-  var _a, _b, _c, _d, _e;
+  var _a2, _b, _c, _d, _e;
   if (concept == null ? void 0 : concept.text) {
     return concept.text;
   }
@@ -10036,7 +10366,7 @@ function getFallbackPrnReasonText(concept) {
     return display;
   }
   const parsed = parseSnomedFindingSitePostcoordinationCode(coding == null ? void 0 : coding.code);
-  const focus = parsed && ((_a = coding == null ? void 0 : coding.system) != null ? _a : SNOMED_SYSTEM5) === SNOMED_SYSTEM5 ? findPrnReasonDefinitionByCoding(SNOMED_SYSTEM5, parsed.focusCode) : void 0;
+  const focus = parsed && ((_a2 = coding == null ? void 0 : coding.system) != null ? _a2 : SNOMED_SYSTEM5) === SNOMED_SYSTEM5 ? findPrnReasonDefinitionByCoding(SNOMED_SYSTEM5, parsed.focusCode) : void 0;
   const focusText = (_d = lowerFirst((_c = focus == null ? void 0 : focus.text) != null ? _c : (_b = focus == null ? void 0 : focus.coding) == null ? void 0 : _b.display)) != null ? _d : display;
   if (focusText && spatialSiteText) {
     return spatialSiteText.toLowerCase().startsWith(`${focusText.toLowerCase()} `) ? spatialSiteText : `${focusText} ${spatialSiteText}`;
@@ -10108,8 +10438,8 @@ function buildFhirBoundsRange(low, high, unit) {
   };
 }
 function parseFhirDurationUnit(quantity) {
-  var _a, _b, _c;
-  const candidate = (_c = (_a = quantity == null ? void 0 : quantity.code) == null ? void 0 : _a.trim().toLowerCase()) != null ? _c : (_b = quantity == null ? void 0 : quantity.unit) == null ? void 0 : _b.trim().toLowerCase();
+  var _a2, _b, _c;
+  const candidate = (_c = (_a2 = quantity == null ? void 0 : quantity.code) == null ? void 0 : _a2.trim().toLowerCase()) != null ? _c : (_b = quantity == null ? void 0 : quantity.unit) == null ? void 0 : _b.trim().toLowerCase();
   switch (candidate) {
     case "s":
     case "sec":
@@ -10151,11 +10481,11 @@ function parseFhirDurationUnit(quantity) {
   }
 }
 function extractCanonicalTimingBounds(repeat) {
-  var _a;
+  var _a2;
   if (!repeat) {
     return {};
   }
-  if (((_a = repeat.boundsDuration) == null ? void 0 : _a.value) !== void 0) {
+  if (((_a2 = repeat.boundsDuration) == null ? void 0 : _a2.value) !== void 0) {
     const durationUnit2 = parseFhirDurationUnit(repeat.boundsDuration);
     if (!durationUnit2) {
       return {};
@@ -10188,9 +10518,9 @@ function extractCanonicalTimingBounds(repeat) {
   };
 }
 function extractCanonicalDoseRange(range) {
-  var _a, _b, _c, _d;
+  var _a2, _b, _c, _d;
   const canonicalRange = {};
-  const lowUnit = (_a = range.low) == null ? void 0 : _a.unit;
+  const lowUnit = (_a2 = range.low) == null ? void 0 : _a2.unit;
   const highUnit = (_b = range.high) == null ? void 0 : _b.unit;
   if (((_c = range.low) == null ? void 0 : _c.value) !== void 0) {
     canonicalRange.low = range.low.value;
@@ -10223,7 +10553,7 @@ function appendWarning(warnings, warning) {
   return warnings;
 }
 function canonicalToFhir(clause, textOverride, options) {
-  var _a, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n, _o, _p, _q, _r, _s, _t, _u, _v, _w, _x, _y, _z, _A, _B, _C, _D, _E, _F, _G;
+  var _a2, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n, _o, _p, _q, _r, _s, _t, _u, _v, _w, _x, _y, _z, _A, _B, _C, _D, _E, _F, _G;
   const dosage = {};
   const repeat = {};
   let hasRepeat = false;
@@ -10261,7 +10591,7 @@ function canonicalToFhir(clause, textOverride, options) {
     repeat.periodMax = schedule.periodMax;
     hasRepeat = true;
   }
-  if ((_a = schedule == null ? void 0 : schedule.dayOfWeek) == null ? void 0 : _a.length) {
+  if ((_a2 = schedule == null ? void 0 : schedule.dayOfWeek) == null ? void 0 : _a2.length) {
     repeat.dayOfWeek = [...schedule.dayOfWeek];
     hasRepeat = true;
   }
@@ -10393,8 +10723,8 @@ function canonicalToFhir(clause, textOverride, options) {
   return dosage;
 }
 function canonicalFromFhir(dosage) {
-  var _a, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n, _o, _p, _q, _r, _s, _t, _u, _v, _w, _x, _y, _z, _A, _B, _C, _D, _E, _F;
-  const rawText = (_a = dosage.text) != null ? _a : "";
+  var _a2, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n, _o, _p, _q, _r, _s, _t, _u, _v, _w, _x, _y, _z, _A, _B, _C, _D, _E, _F;
+  const rawText = (_a2 = dosage.text) != null ? _a2 : "";
   const clause = createEmptyCanonicalClause(rawText);
   let routeCode;
   const routeCoding = (_c = (_b = dosage.route) == null ? void 0 : _b.coding) == null ? void 0 : _c.find((code) => code.system === SNOMED_SYSTEM5);
@@ -10472,8 +10802,8 @@ function canonicalFromFhir(dosage) {
     };
   }
   const prnReasons = ((_y = dosage.asNeededFor) == null ? void 0 : _y.length) ? dosage.asNeededFor.map((concept) => {
-    var _a2;
-    const coding = (_a2 = concept.coding) == null ? void 0 : _a2.find((code) => Boolean(code.code));
+    var _a3;
+    const coding = (_a3 = concept.coding) == null ? void 0 : _a3.find((code) => Boolean(code.code));
     return {
       text: getFallbackPrnReasonText(concept),
       spatialRelation: parseBodySiteSpatialRelationExtension(concept),
@@ -10521,7 +10851,7 @@ function canonicalFromFhir(dosage) {
 
 // src/ir.ts
 function shiftCanonicalSigClauses(clauses, offset) {
-  var _a, _b, _c, _d, _e;
+  var _a2, _b, _c, _d, _e;
   for (const clause of clauses) {
     if (clause.span) {
       clause.span = {
@@ -10549,7 +10879,7 @@ function shiftCanonicalSigClauses(clauses, offset) {
       }
     };
     shiftEvidenceSpans(clause.evidence);
-    shiftEvidenceSpans((_a = clause.dose) == null ? void 0 : _a.evidence);
+    shiftEvidenceSpans((_a2 = clause.dose) == null ? void 0 : _a2.evidence);
     shiftEvidenceSpans((_b = clause.route) == null ? void 0 : _b.evidence);
     shiftEvidenceSpans((_c = clause.site) == null ? void 0 : _c.evidence);
     shiftEvidenceSpans((_d = clause.schedule) == null ? void 0 : _d.evidence);
@@ -10571,8 +10901,8 @@ function getRegisteredSigLocalizations() {
   return Array.from(REGISTERED_LOCALIZATIONS.values());
 }
 function resolveSigLocalization(locale, config) {
-  var _a, _b, _c, _d, _e, _f, _g;
-  const normalizedLocale = (_a = config == null ? void 0 : config.locale) != null ? _a : locale;
+  var _a2, _b, _c, _d, _e, _f, _g;
+  const normalizedLocale = (_a2 = config == null ? void 0 : config.locale) != null ? _a2 : locale;
   const targetKey = normalizedLocale == null ? void 0 : normalizedLocale.toLowerCase();
   const base = targetKey ? REGISTERED_LOCALIZATIONS.get(targetKey) : void 0;
   const inherited = (config == null ? void 0 : config.inherit) ? REGISTERED_LOCALIZATIONS.get(config.inherit.toLowerCase()) : void 0;
@@ -10930,10 +11260,10 @@ var THAI_SITE_TRANSLATIONS = {
   hair: "\u0E40\u0E2A\u0E49\u0E19\u0E1C\u0E21"
 };
 var THAI_SITE_CODE_TRANSLATIONS = (() => {
-  var _a;
+  var _a2;
   const translations = {};
   for (const { names, definition } of DEFAULT_BODY_SITE_SNOMED_SOURCE) {
-    const code = (_a = definition.coding) == null ? void 0 : _a.code;
+    const code = (_a2 = definition.coding) == null ? void 0 : _a2.code;
     if (!code || translations[code]) {
       continue;
     }
@@ -11070,8 +11400,8 @@ var THAI_SITE_FIRST_VERBS = /* @__PURE__ */ new Set([
   "\u0E1E\u0E48\u0E19"
 ]);
 function resolveThaiMethodVerb(clause, grammar) {
-  var _a, _b, _c, _d, _e;
-  const translatedText = getPrimitiveTranslation((_a = clause.method) == null ? void 0 : _a._text, "th");
+  var _a2, _b, _c, _d, _e;
+  const translatedText = getPrimitiveTranslation((_a2 = clause.method) == null ? void 0 : _a2._text, "th");
   if (translatedText) {
     return translatedText;
   }
@@ -11115,14 +11445,14 @@ function joinThaiVerbAndBody(verb, body) {
   return `${verb} ${trimmedBody}`;
 }
 function shouldUseGenericMedicationObjectThai(clause, verb, explicitDosePart) {
-  var _a;
+  var _a2;
   if (explicitDosePart) {
     return false;
   }
   if (THAI_IMPLIED_OBJECT_VERBS.has(verb)) {
     return false;
   }
-  switch ((_a = clause.route) == null ? void 0 : _a.code) {
+  switch ((_a2 = clause.route) == null ? void 0 : _a2.code) {
     case RouteCode["Topical route"]:
     case RouteCode["Transdermal route"]:
     case RouteCode["Nasal route"]:
@@ -11136,14 +11466,14 @@ function shouldUseGenericMedicationObjectThai(clause, verb, explicitDosePart) {
   }
 }
 function shouldSuppressRoutePhraseThai(clause, verb, hasSite, explicitDosePart) {
-  var _a;
+  var _a2;
   if (hasSite || explicitDosePart) {
     return false;
   }
   if (!THAI_SUPPRESSIBLE_ROUTE_VERBS.has(verb)) {
     return false;
   }
-  switch ((_a = clause.route) == null ? void 0 : _a.code) {
+  switch ((_a2 = clause.route) == null ? void 0 : _a2.code) {
     case RouteCode["Topical route"]:
     case RouteCode["Transdermal route"]:
       return true;
@@ -11152,12 +11482,12 @@ function shouldSuppressRoutePhraseThai(clause, verb, hasSite, explicitDosePart)
   }
 }
 function scheduleOf2(clause) {
-  var _a;
-  return (_a = clause.schedule) != null ? _a : {};
+  var _a2;
+  return (_a2 = clause.schedule) != null ? _a2 : {};
 }
 function resolveRouteGrammarThai(clause) {
-  var _a, _b, _c, _d, _e, _f;
-  const routeCode = (_a = clause.route) == null ? void 0 : _a.code;
+  var _a2, _b, _c, _d, _e, _f;
+  const routeCode = (_a2 = clause.route) == null ? void 0 : _a2.code;
   if (routeCode && THAI_ROUTE_GRAMMAR[routeCode]) {
     return (_b = THAI_ROUTE_GRAMMAR[routeCode]) != null ? _b : DEFAULT_THAI_ROUTE_GRAMMAR;
   }
@@ -11314,8 +11644,27 @@ function formatUnitThai(unit, _value, style) {
     sprays: { short: "\u0E1E\u0E48\u0E19", long: "\u0E1E\u0E48\u0E19" },
     drop: { short: "\u0E2B\u0E22\u0E14", long: "\u0E2B\u0E22\u0E14" },
     drops: { short: "\u0E2B\u0E22\u0E14", long: "\u0E2B\u0E22\u0E14" },
+    pump: { short: "\u0E1B\u0E31\u0E4A\u0E21", long: "\u0E1B\u0E31\u0E4A\u0E21" },
+    pumps: { short: "\u0E1B\u0E31\u0E4A\u0E21", long: "\u0E1B\u0E31\u0E4A\u0E21" },
+    actuation: { short: "\u0E04\u0E23\u0E31\u0E49\u0E07", long: "\u0E04\u0E23\u0E31\u0E49\u0E07" },
+    ftu: { short: "FTU", long: "FTU" },
     patch: { short: "\u0E41\u0E1C\u0E48\u0E19", long: "\u0E41\u0E1C\u0E48\u0E19\u0E41\u0E1B\u0E30" },
     patches: { short: "\u0E41\u0E1C\u0E48\u0E19", long: "\u0E41\u0E1C\u0E48\u0E19\u0E41\u0E1B\u0E30" },
+    ring: { short: "\u0E27\u0E07", long: "\u0E27\u0E07" },
+    applicatorful: { short: "\u0E41\u0E2D\u0E1B\u0E1E\u0E25\u0E34\u0E40\u0E04\u0E40\u0E15\u0E2D\u0E23\u0E4C", long: "\u0E41\u0E2D\u0E1B\u0E1E\u0E25\u0E34\u0E40\u0E04\u0E40\u0E15\u0E2D\u0E23\u0E4C" },
+    capful: { short: "\u0E1D\u0E32", long: "\u0E1D\u0E32" },
+    scoop: { short: "\u0E0A\u0E49\u0E2D\u0E19\u0E15\u0E27\u0E07", long: "\u0E0A\u0E49\u0E2D\u0E19\u0E15\u0E27\u0E07" },
+    "pea-sized amount": { short: "\u0E02\u0E19\u0E32\u0E14\u0E40\u0E17\u0E48\u0E32\u0E40\u0E21\u0E47\u0E14\u0E16\u0E31\u0E48\u0E27", long: "\u0E02\u0E19\u0E32\u0E14\u0E40\u0E17\u0E48\u0E32\u0E40\u0E21\u0E47\u0E14\u0E16\u0E31\u0E48\u0E27" },
+    palm: { short: "\u0E1D\u0E48\u0E32\u0E21\u0E37\u0E2D", long: "\u0E1D\u0E48\u0E32\u0E21\u0E37\u0E2D" },
+    handprint: { short: "\u0E2B\u0E19\u0E36\u0E48\u0E07\u0E1D\u0E48\u0E32\u0E21\u0E37\u0E2D", long: "\u0E2B\u0E19\u0E36\u0E48\u0E07\u0E1D\u0E48\u0E32\u0E21\u0E37\u0E2D" },
+    "shot glass": { short: "\u0E41\u0E01\u0E49\u0E27\u0E0A\u0E47\u0E2D\u0E15", long: "\u0E41\u0E01\u0E49\u0E27\u0E0A\u0E47\u0E2D\u0E15" },
+    "finger length": { short: "\u0E04\u0E27\u0E32\u0E21\u0E22\u0E32\u0E27\u0E19\u0E34\u0E49\u0E27", long: "\u0E04\u0E27\u0E32\u0E21\u0E22\u0E32\u0E27\u0E19\u0E34\u0E49\u0E27" },
+    click: { short: "\u0E04\u0E25\u0E34\u0E01", long: "\u0E04\u0E25\u0E34\u0E01" },
+    vial: { short: "\u0E02\u0E27\u0E14", long: "\u0E02\u0E27\u0E14" },
+    ampule: { short: "\u0E41\u0E2D\u0E21\u0E1E\u0E39\u0E25", long: "\u0E41\u0E2D\u0E21\u0E1E\u0E39\u0E25" },
+    packet: { short: "\u0E0B\u0E2D\u0E07", long: "\u0E0B\u0E2D\u0E07" },
+    sachet: { short: "\u0E0B\u0E2D\u0E07", long: "\u0E0B\u0E2D\u0E07" },
+    "stick-pack": { short: "\u0E0B\u0E2D\u0E07\u0E41\u0E17\u0E48\u0E07", long: "\u0E0B\u0E2D\u0E07\u0E41\u0E17\u0E48\u0E07" },
     suppository: { short: "\u0E22\u0E32\u0E40\u0E2B\u0E19\u0E47\u0E1A", long: "\u0E22\u0E32\u0E40\u0E2B\u0E19\u0E47\u0E1A" },
     suppositories: { short: "\u0E22\u0E32\u0E40\u0E2B\u0E19\u0E47\u0E1A", long: "\u0E22\u0E32\u0E40\u0E2B\u0E19\u0E47\u0E1A" }
   };
@@ -11323,7 +11672,7 @@ function formatUnitThai(unit, _value, style) {
   return entry ? entry[style] : unit;
 }
 function describeFrequencyThai(schedule) {
-  var _a, _b;
+  var _a2, _b;
   const frequency = schedule == null ? void 0 : schedule.frequency;
   const frequencyMax = schedule == null ? void 0 : schedule.frequencyMax;
   const period = schedule == null ? void 0 : schedule.period;
@@ -11340,7 +11689,7 @@ function describeFrequencyThai(schedule) {
     return `\u0E27\u0E31\u0E19\u0E25\u0E30 ${stripTrailingZero2(frequency)} \u0E16\u0E36\u0E07 ${stripTrailingZero2(frequencyMax)} \u0E04\u0E23\u0E31\u0E49\u0E07`;
   }
   if (frequency && periodUnit === "d" /* Day */ && (!period || period === 1)) {
-    return (_a = TH_TIMES_PER_DAY[frequency]) != null ? _a : `\u0E27\u0E31\u0E19\u0E25\u0E30 ${stripTrailingZero2(frequency)} \u0E04\u0E23\u0E31\u0E49\u0E07`;
+    return (_a2 = TH_TIMES_PER_DAY[frequency]) != null ? _a2 : `\u0E27\u0E31\u0E19\u0E25\u0E30 ${stripTrailingZero2(frequency)} \u0E04\u0E23\u0E31\u0E49\u0E07`;
   }
   if (periodUnit === "min" /* Minute */ && period) {
     if (periodMax && periodMax !== period) {
@@ -11419,19 +11768,19 @@ function describeFrequencyThai(schedule) {
   return void 0;
 }
 function describeFrequencyCountThai(count) {
-  var _a;
+  var _a2;
   if (!count || count <= 0) {
     return void 0;
   }
-  return (_a = TH_TIMES_PER_DAY[count]) != null ? _a : `\u0E27\u0E31\u0E19\u0E25\u0E30 ${stripTrailingZero2(count)} \u0E04\u0E23\u0E31\u0E49\u0E07`;
+  return (_a2 = TH_TIMES_PER_DAY[count]) != null ? _a2 : `\u0E27\u0E31\u0E19\u0E25\u0E30 ${stripTrailingZero2(count)} \u0E04\u0E23\u0E31\u0E49\u0E07`;
 }
 function describeStandaloneOccurrenceCountThai(schedule) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   const count = schedule == null ? void 0 : schedule.count;
   if (!count || count <= 0) {
     return void 0;
   }
-  if ((schedule == null ? void 0 : schedule.frequency) !== void 0 || (schedule == null ? void 0 : schedule.frequencyMax) !== void 0 || (schedule == null ? void 0 : schedule.period) !== void 0 || (schedule == null ? void 0 : schedule.periodMax) !== void 0 || (schedule == null ? void 0 : schedule.periodUnit) !== void 0 || ((_a = schedule == null ? void 0 : schedule.dayOfWeek) == null ? void 0 : _a.length) || ((_b = schedule == null ? void 0 : schedule.when) == null ? void 0 : _b.length) || ((_c = schedule == null ? void 0 : schedule.timeOfDay) == null ? void 0 : _c.length) || (schedule == null ? void 0 : schedule.duration) !== void 0 || (schedule == null ? void 0 : schedule.durationMax) !== void 0 || (schedule == null ? void 0 : schedule.durationUnit) !== void 0 || (schedule == null ? void 0 : schedule.timingCode)) {
+  if ((schedule == null ? void 0 : schedule.frequency) !== void 0 || (schedule == null ? void 0 : schedule.frequencyMax) !== void 0 || (schedule == null ? void 0 : schedule.period) !== void 0 || (schedule == null ? void 0 : schedule.periodMax) !== void 0 || (schedule == null ? void 0 : schedule.periodUnit) !== void 0 || ((_a2 = schedule == null ? void 0 : schedule.dayOfWeek) == null ? void 0 : _a2.length) || ((_b = schedule == null ? void 0 : schedule.when) == null ? void 0 : _b.length) || ((_c = schedule == null ? void 0 : schedule.timeOfDay) == null ? void 0 : _c.length) || (schedule == null ? void 0 : schedule.duration) !== void 0 || (schedule == null ? void 0 : schedule.durationMax) !== void 0 || (schedule == null ? void 0 : schedule.durationUnit) !== void 0 || (schedule == null ? void 0 : schedule.timingCode)) {
     return void 0;
   }
   return `${stripTrailingZero2(count)} \u0E04\u0E23\u0E31\u0E49\u0E07`;
@@ -11470,8 +11819,8 @@ function summarizeMealTimingGroupThai(group) {
   return `${relationText[group.relation]}${joinMealNamesThai(meals)}`;
 }
 function collectWhenPhrasesThai(schedule, options) {
-  var _a;
-  const when = (_a = schedule == null ? void 0 : schedule.when) != null ? _a : [];
+  var _a2;
+  const when = (_a2 = schedule == null ? void 0 : schedule.when) != null ? _a2 : [];
   if (!when.length) {
     return [];
   }
@@ -11565,8 +11914,8 @@ function combineFrequencyAndEventsThai(frequency, events) {
   return { frequency, event: joinWithAndThai(events) };
 }
 function isOralRouteThai(clause) {
-  var _a, _b, _c;
-  if (((_a = clause.route) == null ? void 0 : _a.code) === RouteCode["Oral route"]) {
+  var _a2, _b, _c;
+  if (((_a2 = clause.route) == null ? void 0 : _a2.code) === RouteCode["Oral route"]) {
     return true;
   }
   const text = (_c = (_b = clause.route) == null ? void 0 : _b.text) == null ? void 0 : _c.trim().toLowerCase();
@@ -11576,7 +11925,7 @@ function isOralRouteThai(clause) {
   return text === "po" || text === "oral" || text.includes("mouth") || text.includes("per os");
 }
 function buildRoutePhraseThai(clause, grammar, hasSite) {
-  var _a, _b;
+  var _a2, _b;
   if (grammar.verb === "\u0E23\u0E31\u0E1A\u0E1B\u0E23\u0E30\u0E17\u0E32\u0E19" && isOralRouteThai(clause)) {
     return void 0;
   }
@@ -11586,7 +11935,7 @@ function buildRoutePhraseThai(clause, grammar, hasSite) {
   if (typeof grammar.routePhrase === "string") {
     return grammar.routePhrase;
   }
-  const text = (_b = (_a = clause.route) == null ? void 0 : _a.text) == null ? void 0 : _b.trim();
+  const text = (_b = (_a2 = clause.route) == null ? void 0 : _a2.text) == null ? void 0 : _b.trim();
   if (!text) {
     return void 0;
   }
@@ -11621,8 +11970,8 @@ function buildRoutePhraseThai(clause, grammar, hasSite) {
   return text;
 }
 function formatSiteThai(clause, grammar) {
-  var _a, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n, _o;
-  const text = ((_b = (_a = clause.site) == null ? void 0 : _a.text) == null ? void 0 : _b.trim()) || ((_e = (_d = (_c = clause.site) == null ? void 0 : _c.coding) == null ? void 0 : _d.display) == null ? void 0 : _e.trim());
+  var _a2, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n, _o;
+  const text = ((_b = (_a2 = clause.site) == null ? void 0 : _a2.text) == null ? void 0 : _b.trim()) || ((_e = (_d = (_c = clause.site) == null ? void 0 : _c.coding) == null ? void 0 : _d.display) == null ? void 0 : _e.trim());
   const lower = text == null ? void 0 : text.toLowerCase();
   const codingCode = (_g = (_f = clause.site) == null ? void 0 : _f.coding) == null ? void 0 : _g.code;
   const routeText = (_i = (_h = clause.route) == null ? void 0 : _h.text) == null ? void 0 : _i.trim().toLowerCase();
@@ -11679,8 +12028,8 @@ var THAI_SPATIAL_TARGET_TRANSLATION_OVERRIDES = {
   belly: "\u0E17\u0E49\u0E2D\u0E07"
 };
 function translateSpatialTargetThai(relation) {
-  var _a, _b;
-  const normalizedTarget = normalizeBodySiteKey((_a = relation.targetText) != null ? _a : "");
+  var _a2, _b;
+  const normalizedTarget = normalizeBodySiteKey((_a2 = relation.targetText) != null ? _a2 : "");
   const override = THAI_SPATIAL_TARGET_TRANSLATION_OVERRIDES[normalizedTarget];
   return override != null ? override : translateSiteThai(
     relation.targetText,
@@ -11688,8 +12037,8 @@ function translateSpatialTargetThai(relation) {
   );
 }
 function translateSpatialSiteThai(site, relation) {
-  var _a;
-  const spatialRelation = relation != null ? relation : site ? (_a = resolveBodySitePhrase(site)) == null ? void 0 : _a.spatialRelation : void 0;
+  var _a2;
+  const spatialRelation = relation != null ? relation : site ? (_a2 = resolveBodySitePhrase(site)) == null ? void 0 : _a2.spatialRelation : void 0;
   if (!(spatialRelation == null ? void 0 : spatialRelation.relationText)) {
     return void 0;
   }
@@ -11742,8 +12091,8 @@ function translateSiteThai(site, code, spatialRelation) {
   return site;
 }
 function describeDayOfWeekThai(schedule) {
-  var _a;
-  const dayOfWeek = (_a = schedule == null ? void 0 : schedule.dayOfWeek) != null ? _a : [];
+  var _a2;
+  const dayOfWeek = (_a2 = schedule == null ? void 0 : schedule.dayOfWeek) != null ? _a2 : [];
   if (!dayOfWeek.length) {
     return void 0;
   }
@@ -11793,7 +12142,7 @@ function describeDurationThai(schedule) {
   return `\u0E40\u0E1B\u0E47\u0E19\u0E40\u0E27\u0E25\u0E32 ${stripTrailingZero2(schedule.duration)} ${label()}`;
 }
 function findPrnReasonDefinitionByPossiblyPostcoordinatedCoding(system, code) {
-  var _a;
+  var _a2;
   const direct = findPrnReasonDefinitionByCoding(system, code);
   if (direct) {
     return direct;
@@ -11802,11 +12151,11 @@ function findPrnReasonDefinitionByPossiblyPostcoordinatedCoding(system, code) {
   if (!normalizedSystem.includes("snomed.info/sct")) {
     return void 0;
   }
-  return findPrnReasonDefinitionByCoding(system, (_a = code.split(":")[0]) != null ? _a : code);
+  return findPrnReasonDefinitionByCoding(system, (_a2 = code.split(":")[0]) != null ? _a2 : code);
 }
 function translatePrnReasonThai(reason) {
-  var _a, _b, _c, _d, _e;
-  let text = (_b = reason.text) != null ? _b : (_a = reason.coding) == null ? void 0 : _a.display;
+  var _a2, _b, _c, _d, _e;
+  let text = (_b = reason.text) != null ? _b : (_a2 = reason.coding) == null ? void 0 : _a2.display;
   const coding = reason.coding;
   if (coding == null ? void 0 : coding.code) {
     const definition = findPrnReasonDefinitionByPossiblyPostcoordinatedCoding(
@@ -11822,8 +12171,8 @@ function translatePrnReasonThai(reason) {
   return text;
 }
 function formatAsNeededThai(clause) {
-  var _a, _b, _c, _d, _e, _f;
-  if (!((_a = clause.prn) == null ? void 0 : _a.enabled)) {
+  var _a2, _b, _c, _d, _e, _f;
+  if (!((_a2 = clause.prn) == null ? void 0 : _a2.enabled)) {
     return void 0;
   }
   if ((_b = clause.prn.reasons) == null ? void 0 : _b.length) {
@@ -11845,14 +12194,14 @@ function formatAsNeededThai(clause) {
   return "\u0E43\u0E0A\u0E49\u0E40\u0E21\u0E37\u0E48\u0E2D\u0E08\u0E33\u0E40\u0E1B\u0E47\u0E19";
 }
 function formatShortThai(clause) {
-  var _a, _b, _c, _d, _e, _f;
+  var _a2, _b, _c, _d, _e, _f;
   const schedule = scheduleOf2(clause);
   const parts = [];
   const dose = formatDoseThaiShort(clause.dose);
   if (dose) {
     parts.push(dose);
   }
-  if ((_a = clause.route) == null ? void 0 : _a.code) {
+  if ((_a2 = clause.route) == null ? void 0 : _a2.code) {
     const short = ROUTE_SHORT2[clause.route.code];
     if (short) {
       parts.push(short);
@@ -11904,7 +12253,7 @@ function formatShortThai(clause) {
   return parts.filter(Boolean).join(" ");
 }
 function formatLongThai(clause, options) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   const schedule = scheduleOf2(clause);
   const grammar = resolveRouteGrammarThai(clause);
   const verb = resolveThaiMethodVerb(clause, grammar);
@@ -11922,7 +12271,7 @@ function formatLongThai(clause, options) {
     explicitDosePart
   ) ? void 0 : buildRoutePhraseThai(clause, grammar, Boolean(sitePart));
   const standaloneOccurrenceCount = describeStandaloneOccurrenceCountThai(schedule);
-  const frequencyPart = (_b = (_a = describeFrequencyThai(schedule)) != null ? _a : standaloneOccurrenceCount) != null ? _b : describeFrequencyCountThai(inferDailyOccurrenceCount(schedule, options));
+  const frequencyPart = (_b = (_a2 = describeFrequencyThai(schedule)) != null ? _a2 : standaloneOccurrenceCount) != null ? _b : describeFrequencyCountThai(inferDailyOccurrenceCount(schedule, options));
   const eventParts = collectWhenPhrasesThai(schedule, options);
   if ((_c = schedule.timeOfDay) == null ? void 0 : _c.length) {
     const timeStrings = [];
@@ -11998,8 +12347,8 @@ function formatLongThai(clause, options) {
   return trailingInstructionText ? `${baseSentence} ${trailingInstructionText}` : baseSentence;
 }
 function formatAdditionalInstructionsThai(clause) {
-  var _a, _b, _c, _d, _e, _f, _g, _h, _i, _j;
-  const instructions = (_a = clause.additionalInstructions) != null ? _a : [];
+  var _a2, _b, _c, _d, _e, _f, _g, _h, _i, _j;
+  const instructions = (_a2 = clause.additionalInstructions) != null ? _a2 : [];
   if (!instructions.length) {
     return void 0;
   }
@@ -12062,7 +12411,7 @@ function tokenSpanLength(sign) {
   return Math.max(0, sign.span.end - sign.span.start);
 }
 function countSynsemFeatures(sign) {
-  var _a;
+  var _a2;
   let count = 0;
   const { head, valence, cont } = sign.synsem;
   if (head.method) count += 1;
@@ -12071,7 +12420,7 @@ function countSynsemFeatures(sign) {
   if (head.schedule) count += 1;
   if (valence.site) count += 1;
   if (valence.prn) count += 1;
-  if ((_a = valence.instructions) == null ? void 0 : _a.length) count += 1;
+  if ((_a2 = valence.instructions) == null ? void 0 : _a2.length) count += 1;
   if (valence.patientInstruction) count += 1;
   if (cont.clauseKind) count += 1;
   return count;
@@ -12138,8 +12487,8 @@ function pushUnique(signs, seen, sign) {
   return true;
 }
 function parseHpsgChart(context, grammar, options = {}) {
-  var _a, _b;
-  const limit = (_a = options.limit) != null ? _a : context.tokens.length;
+  var _a2, _b;
+  const limit = (_a2 = options.limit) != null ? _a2 : context.tokens.length;
   const maxIterations = (_b = options.maxIterations) != null ? _b : Math.max(16, limit * limit * 2);
   const signs = [];
   const seen = /* @__PURE__ */ new Map();
@@ -12186,7 +12535,7 @@ function parseHpsgChart(context, grammar, options = {}) {
 
 // src/hpsg/projection.ts
 function applySchedule(state, schedule, deps) {
-  var _a;
+  var _a2;
   if (schedule.timingCode !== void 0) {
     state.timingCode = schedule.timingCode;
   }
@@ -12225,7 +12574,7 @@ function applySchedule(state, schedule, deps) {
   if (schedule.dayOfWeek) {
     deps.addDayOfWeekList(state, schedule.dayOfWeek);
   }
-  if ((_a = schedule.timeOfDay) == null ? void 0 : _a.length) {
+  if ((_a2 = schedule.timeOfDay) == null ? void 0 : _a2.length) {
     const existing = state.timeOfDay ? state.timeOfDay.slice() : [];
     for (const time of schedule.timeOfDay) {
       if (existing.indexOf(time) === -1) {
@@ -12243,7 +12592,7 @@ function findTokenByIndex(tokens, tokenIndex) {
   return tokens.find((candidate) => candidate.index === tokenIndex);
 }
 function projectHpsgSignToState(sign, state, tokens, deps) {
-  var _a, _b, _c, _d;
+  var _a2, _b, _c, _d;
   const method = sign.synsem.head.method;
   if (method) {
     state.methodVerb = method.verb;
@@ -12287,7 +12636,7 @@ function projectHpsgSignToState(sign, state, tokens, deps) {
     if (prn.reasonText !== void 0) {
       state.asNeededReason = prn.reasonText;
     }
-    if ((_a = prn.reasons) == null ? void 0 : _a.length) {
+    if ((_a2 = prn.reasons) == null ? void 0 : _a2.length) {
       state.asNeededReasons = prn.reasons.map((reason) => ({
         text: reason.text
       }));
@@ -12305,8 +12654,8 @@ function projectHpsgSignToState(sign, state, tokens, deps) {
     for (const instruction of instructions) {
       if (!existing.some(
         (candidate) => {
-          var _a2, _b2;
-          return candidate.text === instruction.text && ((_a2 = candidate.coding) == null ? void 0 : _a2.code) === ((_b2 = instruction.coding) == null ? void 0 : _b2.code);
+          var _a3, _b2;
+          return candidate.text === instruction.text && ((_a3 = candidate.coding) == null ? void 0 : _a3.code) === ((_b2 = instruction.coding) == null ? void 0 : _b2.code);
         }
       )) {
         existing.push({
@@ -12374,13 +12723,13 @@ function mergeOptionalScalar(left, right) {
   return left !== void 0 ? left : right;
 }
 function sameCoding(left, right) {
-  var _a, _b;
+  var _a2, _b;
   if (!(left == null ? void 0 : left.code) || !(right == null ? void 0 : right.code)) {
     return (left == null ? void 0 : left.code) === (right == null ? void 0 : right.code);
   }
   const leftVersion = left.version;
   const rightVersion = right.version;
-  return left.code === right.code && ((_a = left.system) != null ? _a : "http://snomed.info/sct") === ((_b = right.system) != null ? _b : "http://snomed.info/sct") && leftVersion === rightVersion;
+  return left.code === right.code && ((_a2 = left.system) != null ? _a2 : "http://snomed.info/sct") === ((_b = right.system) != null ? _b : "http://snomed.info/sct") && leftVersion === rightVersion;
 }
 function sameOptionalText(left, right) {
   return (left != null ? left : "") === (right != null ? right : "");
@@ -12476,11 +12825,11 @@ function mergePrnReasons(left, right) {
   return result.length ? result : void 0;
 }
 function samePrnLookupRequest(left, right) {
-  var _a, _b, _c, _d, _e, _f, _g, _h;
+  var _a2, _b, _c, _d, _e, _f, _g, _h;
   if (!left || !right) {
     return left === right;
   }
-  return left.originalText === right.originalText && left.text === right.text && left.normalized === right.normalized && left.canonical === right.canonical && sameOptionalText(left.headCanonical, right.headCanonical) && sameOptionalText(left.locativeSiteCanonical, right.locativeSiteCanonical) && sameCoding(left.locativeSiteCoding, right.locativeSiteCoding) && sameSpatialRelation(left.locativeSiteSpatialRelation, right.locativeSiteSpatialRelation) && left.isProbe === right.isProbe && left.inputText === right.inputText && sameOptionalText(left.sourceText, right.sourceText) && ((_b = (_a = left.range) == null ? void 0 : _a.start) != null ? _b : -1) === ((_d = (_c = right.range) == null ? void 0 : _c.start) != null ? _d : -1) && ((_f = (_e = left.range) == null ? void 0 : _e.end) != null ? _f : -1) === ((_h = (_g = right.range) == null ? void 0 : _g.end) != null ? _h : -1);
+  return left.originalText === right.originalText && left.text === right.text && left.normalized === right.normalized && left.canonical === right.canonical && sameOptionalText(left.headCanonical, right.headCanonical) && sameOptionalText(left.locativeSiteCanonical, right.locativeSiteCanonical) && sameCoding(left.locativeSiteCoding, right.locativeSiteCoding) && sameSpatialRelation(left.locativeSiteSpatialRelation, right.locativeSiteSpatialRelation) && left.isProbe === right.isProbe && left.inputText === right.inputText && sameOptionalText(left.sourceText, right.sourceText) && ((_b = (_a2 = left.range) == null ? void 0 : _a2.start) != null ? _b : -1) === ((_d = (_c = right.range) == null ? void 0 : _c.start) != null ? _d : -1) && ((_f = (_e = left.range) == null ? void 0 : _e.end) != null ? _f : -1) === ((_h = (_g = right.range) == null ? void 0 : _g.end) != null ? _h : -1);
 }
 function mergePrnLookupRequests(left, right) {
   const result = [];
@@ -12563,7 +12912,7 @@ function mergeSchedule(left, right) {
   };
 }
 function unifySynsem(left, right, context) {
-  var _a;
+  var _a2;
   const method = mergeMethod(left.head.method, right.head.method);
   if (method === void 0 && left.head.method && right.head.method) {
     return void 0;
@@ -12605,7 +12954,7 @@ function unifySynsem(left, right, context) {
       )
     },
     cont: {
-      clauseKind: (_a = left.cont.clauseKind) != null ? _a : right.cont.clauseKind
+      clauseKind: (_a2 = left.cont.clauseKind) != null ? _a2 : right.cont.clauseKind
     }
   };
 }
@@ -12740,8 +13089,10 @@ var ADMINISTRATION_METHOD_WORDS = /* @__PURE__ */ new Set([
   "spray",
   "take",
   "drink",
+  "inhale",
   "swallow",
   "use",
+  "inject",
   "insert",
   "instill",
   "reapply",
@@ -13102,12 +13453,12 @@ function annotateLexTokens(tokens) {
   return tokens.map((token) => annotateLexToken(token));
 }
 function hasTokenWordClass(token, wordClass) {
-  var _a;
-  return Boolean(((_a = token == null ? void 0 : token.annotations) == null ? void 0 : _a.wordClasses) && arrayIncludes(token.annotations.wordClasses, wordClass));
+  var _a2;
+  return Boolean(((_a2 = token == null ? void 0 : token.annotations) == null ? void 0 : _a2.wordClasses) && arrayIncludes(token.annotations.wordClasses, wordClass));
 }
 function getDayOfWeekMeaning(token) {
-  var _a;
-  if ((_a = token == null ? void 0 : token.annotations) == null ? void 0 : _a.dayOfWeek) {
+  var _a2;
+  if ((_a2 = token == null ? void 0 : token.annotations) == null ? void 0 : _a2.dayOfWeek) {
     return token.annotations.dayOfWeek.slice();
   }
   if (!token) {
@@ -13116,8 +13467,8 @@ function getDayOfWeekMeaning(token) {
   return resolveDayMeaning(token.lower);
 }
 function getRouteMeaning(token) {
-  var _a, _b;
-  if ((_b = (_a = token == null ? void 0 : token.annotations) == null ? void 0 : _a.routeCandidates) == null ? void 0 : _b.length) {
+  var _a2, _b;
+  if ((_b = (_a2 = token == null ? void 0 : token.annotations) == null ? void 0 : _a2.routeCandidates) == null ? void 0 : _b.length) {
     return token.annotations.routeCandidates[0];
   }
   if (!token) {
@@ -13129,8 +13480,8 @@ function getRouteMeaning(token) {
   }) : void 0;
 }
 function getSiteMeaningCandidates(token) {
-  var _a, _b;
-  if ((_b = (_a = token == null ? void 0 : token.annotations) == null ? void 0 : _a.siteCandidates) == null ? void 0 : _b.length) {
+  var _a2, _b;
+  if ((_b = (_a2 = token == null ? void 0 : token.annotations) == null ? void 0 : _a2.siteCandidates) == null ? void 0 : _b.length) {
     return token.annotations.siteCandidates.slice();
   }
   if (!token) {
@@ -13281,6 +13632,7 @@ function pad2(value) {
   return value < 10 ? `0${value}` : String(value);
 }
 function parseClockToken(token, meridiemToken) {
+  var _a2;
   if (!token) {
     return void 0;
   }
@@ -13288,6 +13640,9 @@ function parseClockToken(token, meridiemToken) {
   if (lower.startsWith("@")) {
     lower = lower.slice(1);
   }
+  if (token.derived && ((_a2 = token.sourceText) == null ? void 0 : _a2.includes("/")) && /^[0-9]+(?:\.[0-9]+)?$/.test(lower)) {
+    return void 0;
+  }
   const meridiem = meridiemToken ? normalizeTokenLower(meridiemToken) : void 0;
   let hour;
   let minute = 0;
@@ -13396,7 +13751,7 @@ function emptySynsem() {
   };
 }
 function lexicalSign(args) {
-  var _a, _b;
+  var _a2, _b;
   const tokenIndices = args.tokens.map((token) => token.index).filter((index) => Number.isFinite(index));
   if (!tokenIndices.length) {
     throw new Error(`Cannot build lexical sign for ${args.rule} without token indices.`);
@@ -13408,7 +13763,7 @@ function lexicalSign(args) {
     span: { start, end },
     tokens: args.tokens,
     synsem: args.synsem,
-    consumedTokenIndices: (_a = args.consumedTokenIndices) != null ? _a : tokenIndices,
+    consumedTokenIndices: (_a2 = args.consumedTokenIndices) != null ? _a2 : tokenIndices,
     siteTokenIndices: args.siteTokenIndices,
     warnings: args.warnings,
     evidence: [
@@ -13438,8 +13793,8 @@ function timingCodeForDailyFrequency(value) {
 }
 function multiplicativeDoseFrequencyRule() {
   return lexicalRule("hpsg.lex.doseFrequency.multiplicative", (context, start) => {
-    var _a;
-    const first = (_a = tokensAvailable(context, start, 1)) == null ? void 0 : _a[0];
+    var _a2;
+    const first = (_a2 = tokensAvailable(context, start, 1)) == null ? void 0 : _a2[0];
     if (!first) {
       return [];
     }
@@ -13569,8 +13924,8 @@ function compactIntervalRule() {
 }
 function separatedIntervalRule() {
   return lexicalRule("hpsg.lex.schedule.separatedInterval", (context, start) => {
-    var _a;
-    const lead = (_a = tokensAvailable(context, start, 1)) == null ? void 0 : _a[0];
+    var _a2;
+    const lead = (_a2 = tokensAvailable(context, start, 1)) == null ? void 0 : _a2[0];
     if (!lead || !EVERY_INTERVAL_TOKENS.has(normalizeTokenLower(lead))) {
       return [];
     }
@@ -13671,8 +14026,8 @@ function separatedIntervalRule() {
 }
 function countFrequencyRule() {
   return lexicalRule("hpsg.lex.schedule.frequency", (context, start) => {
-    var _a, _b, _c, _d;
-    const token = (_a = tokensAvailable(context, start, 1)) == null ? void 0 : _a[0];
+    var _a2, _b, _c, _d;
+    const token = (_a2 = tokensAvailable(context, start, 1)) == null ? void 0 : _a2[0];
     if (!token) {
       return [];
     }
@@ -13801,8 +14156,8 @@ function countFrequencyRule() {
 }
 function timingLexicalRule() {
   return lexicalRule("hpsg.lex.schedule.timing", (context, start) => {
-    var _a;
-    const token = (_a = tokensAvailable(context, start, 1)) == null ? void 0 : _a[0];
+    var _a2;
+    const token = (_a2 = tokensAvailable(context, start, 1)) == null ? void 0 : _a2[0];
     if (!token) {
       return [];
     }
@@ -13893,16 +14248,16 @@ function timingLexicalRule() {
   });
 }
 function mealTimingForRelation(relation, meal) {
-  var _a;
-  return (_a = MEAL_TIMING_BY_RELATION.get(relation)) == null ? void 0 : _a.get(meal);
+  var _a2;
+  return (_a2 = MEAL_TIMING_BY_RELATION.get(relation)) == null ? void 0 : _a2.get(meal);
 }
 function mealRelationFromToken(lower) {
   return MEAL_RELATION_BY_TOKEN.get(lower);
 }
 function eventTimingPhraseRule() {
   return lexicalRule("hpsg.lex.schedule.eventPhrase", (context, start) => {
-    var _a;
-    const first = (_a = tokensAvailable(context, start, 1)) == null ? void 0 : _a[0];
+    var _a2;
+    const first = (_a2 = tokensAvailable(context, start, 1)) == null ? void 0 : _a2[0];
     if (!first) {
       return [];
     }
@@ -14051,8 +14406,8 @@ function expandDayRange(startDay, endDay) {
 }
 function dayRangeLexicalRule() {
   return lexicalRule("hpsg.lex.schedule.dayRange", (context, start) => {
-    var _a;
-    const first = (_a = tokensAvailable(context, start, 1)) == null ? void 0 : _a[0];
+    var _a2;
+    const first = (_a2 = tokensAvailable(context, start, 1)) == null ? void 0 : _a2[0];
     if (!first) {
       return [];
     }
@@ -14121,8 +14476,8 @@ function dayRangeLexicalRule() {
 }
 function countAndDurationRule() {
   return lexicalRule("hpsg.lex.schedule.limit", (context, start) => {
-    var _a, _b;
-    const token = (_a = tokensAvailable(context, start, 1)) == null ? void 0 : _a[0];
+    var _a2, _b;
+    const token = (_a2 = tokensAvailable(context, start, 1)) == null ? void 0 : _a2[0];
     if (!token) {
       return [];
     }
@@ -14330,57 +14685,180 @@ function isScheduleLead(context, index) {
   return false;
 }
 
+// src/unit-terminology.json
+var unit_terminology_default = {
+  terms: [
+    { unit: "mg", kind: "metric" },
+    { unit: "g", kind: "metric" },
+    { unit: "kg", kind: "metric" },
+    { unit: "mcg", kind: "metric" },
+    { unit: "ug", kind: "metric" },
+    { unit: "microg", kind: "metric" },
+    { unit: "ng", kind: "metric" },
+    { unit: "mL", kind: "metric" },
+    { unit: "L", kind: "metric" },
+    { unit: "dL", kind: "metric" },
+    { unit: "mcL", kind: "metric" },
+    { unit: "uL", kind: "metric" },
+    { unit: "nL", kind: "metric" },
+    { unit: "cm3", kind: "metric" },
+    { unit: "tsp", kind: "metric", aliases: ["teaspoon"] },
+    { unit: "tbsp", kind: "metric", aliases: ["tablespoon"] },
+    { unit: "U", kind: "biologic_unit", aliases: ["unit", "units"] },
+    { unit: "IU", kind: "biologic_unit", aliases: ["iu", "ius"] },
+    { unit: "puff", kind: "device_actuation", aliases: ["puffs", "inhalation", "inhalations"] },
+    { unit: "spray", kind: "device_actuation", aliases: ["sprays"] },
+    { unit: "pump", kind: "device_actuation", aliases: ["pumps"] },
+    { unit: "actuation", kind: "device_actuation", aliases: ["actuations"] },
+    {
+      unit: "drop",
+      kind: "product_specific_amount",
+      aliases: ["drops", "gtt", "gtts", "eyedrop", "eyedrops"],
+      approximateQuantity: {
+        value: 0.05,
+        unit: "mL",
+        confidence: "approximate",
+        basis: "Generic ophthalmic drop default; product/dropper-specific values should override this",
+        source: "https://pmc.ncbi.nlm.nih.gov/articles/PMC3217709/"
+      }
+    },
+    { unit: "dropperful", kind: "product_specific_amount", aliases: ["dropperfuls"] },
+    {
+      unit: "drop/min",
+      kind: "infusion_rate",
+      aliases: ["drops/min", "gtt/min", "gtts/min", "drop per minute", "drops per minute"],
+      parseAsDose: false
+    },
+    { unit: "applicatorful", kind: "product_specific_amount", aliases: ["applicatorfuls", "applicator", "applicators", "full applicator", "full applicators"] },
+    { unit: "capful", kind: "product_specific_amount", aliases: ["capfuls", "cap to line", "cap filled to line"] },
+    { unit: "scoop", kind: "product_specific_amount", aliases: ["scoops"] },
+    {
+      unit: "pea-sized amount",
+      kind: "product_specific_amount",
+      aliases: [
+        "pea sized amount",
+        "pea-sized",
+        "pea sized",
+        "pea size amount",
+        "pea-size amount",
+        "\u0E40\u0E21\u0E47\u0E14\u0E16\u0E31\u0E48\u0E27",
+        "\u0E40\u0E21\u0E47\u0E14\u0E16\u0E31\u0E48\u0E27\u0E40\u0E02\u0E35\u0E22\u0E27",
+        "\u0E40\u0E21\u0E25\u0E47\u0E14\u0E16\u0E31\u0E48\u0E27",
+        "\u0E02\u0E19\u0E32\u0E14\u0E40\u0E21\u0E47\u0E14\u0E16\u0E31\u0E48\u0E27",
+        "\u0E02\u0E19\u0E32\u0E14\u0E40\u0E21\u0E47\u0E14\u0E16\u0E31\u0E48\u0E27\u0E40\u0E02\u0E35\u0E22\u0E27",
+        "\u0E02\u0E19\u0E32\u0E14\u0E40\u0E21\u0E25\u0E47\u0E14\u0E16\u0E31\u0E48\u0E27"
+      ],
+      approximateQuantity: {
+        value: 0.25,
+        unit: "mL",
+        confidence: "approximate",
+        basis: "Generic pea-sized volume proxy; product labels may define mass and should override when known",
+        source: "https://www.accessdata.fda.gov/drugsatfda_docs/nda/2000/21-108_Renova_Medr_P1.pdf"
+      }
+    },
+    {
+      unit: "shot glass",
+      kind: "product_specific_amount",
+      aliases: ["shotglass", "shot glasses"],
+      approximateQuantity: {
+        value: 29.5735,
+        unit: "mL",
+        confidence: "approximate",
+        basis: "AAD sunscreen full-body adult amount: about 1 ounce, roughly a shot glass",
+        source: "https://www.aad.org/media/stats-sunscreen"
+      }
+    },
+    { unit: "finger length", kind: "product_specific_amount", aliases: ["finger lengths", "two-finger rule", "two finger rule", "two-finger method", "two finger method"] },
+    {
+      unit: "FTU",
+      kind: "product_specific_amount",
+      aliases: ["ftu", "ftus", "f.t.u", "f.t.u.", "fingertip unit", "fingertip units"],
+      approximateQuantity: {
+        value: 0.5,
+        unit: "g",
+        confidence: "approximate",
+        basis: "DermNet adult male fingertip unit default",
+        source: "https://dermnetnz.org/topics/fingertip-unit"
+      }
+    },
+    { unit: "cm ribbon", kind: "length_of_product" },
+    { unit: "inch ribbon", kind: "length_of_product", aliases: ["inch strip"] },
+    { unit: "cm strip", kind: "length_of_product" },
+    { unit: "cm line", kind: "length_of_product" },
+    { unit: "inch line", kind: "length_of_product" },
+    { unit: "palm", kind: "body_area_proxy", aliases: ["palms"] },
+    { unit: "handprint", kind: "body_area_proxy", aliases: ["handprints", "hand print", "hand prints"] },
+    { unit: "% BSA", kind: "body_area_proxy", aliases: ["%BSA", "% TBSA", "%TBSA", "percent BSA", "percent TBSA"] },
+    { unit: "tab", kind: "counted_presentation", aliases: ["tablet"] },
+    { unit: "cap", kind: "counted_presentation", aliases: ["capsule"] },
+    { unit: "patch", kind: "counted_presentation", aliases: ["patches", "system", "systems", "transdermal system", "transdermal systems"] },
+    { unit: "ring", kind: "counted_presentation", aliases: ["rings"] },
+    { unit: "suppository", kind: "counted_presentation", aliases: ["suppositories"] },
+    { unit: "pessary", kind: "counted_presentation", aliases: ["pessaries"] },
+    { unit: "insert", kind: "counted_presentation", aliases: ["inserts"] },
+    { unit: "ovule", kind: "counted_presentation", aliases: ["ovules"] },
+    { unit: "enema", kind: "counted_presentation", aliases: ["enemas"] },
+    { unit: "swab", kind: "counted_presentation", aliases: ["swabs"] },
+    { unit: "pad", kind: "counted_presentation", aliases: ["pads"] },
+    { unit: "wipe", kind: "counted_presentation", aliases: ["wipes"] },
+    { unit: "stick", kind: "counted_presentation", aliases: ["sticks"] },
+    { unit: "stick-pack", kind: "counted_presentation", aliases: ["stick pack", "stick packs", "stick-packs"] },
+    { unit: "implant", kind: "counted_presentation", aliases: ["implants"] },
+    { unit: "pellet", kind: "counted_presentation", aliases: ["pellets"] },
+    { unit: "lozenge", kind: "counted_presentation", aliases: ["lozenges"] },
+    { unit: "troche", kind: "counted_presentation", aliases: ["troches"] },
+    { unit: "wafer", kind: "counted_presentation", aliases: ["wafers"] },
+    { unit: "film", kind: "counted_presentation", aliases: ["films"] },
+    { unit: "strip", kind: "counted_presentation", aliases: ["strips"] },
+    { unit: "softgel", kind: "counted_presentation", aliases: ["softgels"] },
+    { unit: "tube", kind: "counted_presentation", aliases: ["tubes"] },
+    { unit: "bottle", kind: "counted_presentation", aliases: ["bottles"] },
+    { unit: "container", kind: "counted_presentation", aliases: ["containers"] },
+    { unit: "jar", kind: "counted_presentation", aliases: ["jars"] },
+    { unit: "packet", kind: "counted_presentation", aliases: ["packets"] },
+    { unit: "sachet", kind: "counted_presentation", aliases: ["sachets"] },
+    { unit: "vial", kind: "counted_presentation", aliases: ["vials", "unit-dose vial", "unit-dose vials", "unit dose vial", "unit dose vials"] },
+    { unit: "ampule", kind: "counted_presentation", aliases: ["amp", "amps", "ampules", "ampoule", "ampoules"] },
+    { unit: "nebule", kind: "counted_presentation", aliases: ["nebules"] },
+    { unit: "respule", kind: "counted_presentation", aliases: ["respules"] },
+    { unit: "syringe", kind: "counted_presentation", aliases: ["syringes"] },
+    { unit: "pen", kind: "counted_presentation", aliases: ["pens"] },
+    { unit: "cartridge", kind: "counted_presentation", aliases: ["cartridges"] },
+    { unit: "canister", kind: "counted_presentation", aliases: ["canisters"] },
+    { unit: "blister", kind: "counted_presentation", aliases: ["blisters"] },
+    { unit: "bag", kind: "counted_presentation", aliases: ["bags"] },
+    { unit: "pod", kind: "counted_presentation", aliases: ["pods"] },
+    { unit: "click", kind: "device_actuation", aliases: ["clicks", "pen click", "pen clicks", "dial click", "dial clicks"] }
+  ]
+};
+
 // src/unit-lexicon.ts
 var HOUSEHOLD_VOLUME_UNIT_SET = new Set(
   HOUSEHOLD_VOLUME_UNITS.map((unit) => unit.toLowerCase())
 );
-var DISCRETE_UNIT_SET = /* @__PURE__ */ new Set([
-  "tab",
-  "tabs",
-  "tablet",
-  "tablets",
-  "cap",
-  "caps",
-  "capsule",
-  "capsules",
-  "puff",
-  "puffs",
-  "spray",
-  "sprays",
-  "drop",
-  "drops",
-  "patch",
-  "patches",
-  "suppository",
-  "suppositories",
-  "implant",
-  "implants",
-  "piece",
-  "pieces",
-  "stick",
-  "sticks",
-  "pump",
-  "pumps",
-  "squeeze",
-  "squeezes",
-  "applicatorful",
-  "applicatorfuls",
-  "capful",
-  "capfuls",
-  "scoop",
-  "scoops",
-  "application",
-  "applications",
-  "ribbon",
-  "pessary",
-  "pessaries",
-  "lozenge",
-  "lozenges"
+var DOSE_UNIT_TERMINOLOGY = unit_terminology_default.terms;
+var DOSE_UNIT_TERMINOLOGY_BY_KEY = /* @__PURE__ */ new Map();
+var DISCRETE_UNIT_KINDS = /* @__PURE__ */ new Set([
+  "biologic_unit",
+  "counted_presentation",
+  "device_actuation",
+  "product_specific_amount",
+  "length_of_product"
 ]);
+var _a;
+for (const entry of DOSE_UNIT_TERMINOLOGY) {
+  const keys = [entry.unit, ...(_a = entry.aliases) != null ? _a : []];
+  for (const key of keys) {
+    const normalized = normalizeUnitKey(key);
+    if (normalized) {
+      DOSE_UNIT_TERMINOLOGY_BY_KEY.set(normalized, entry);
+    }
+  }
+}
 function normalizeUnit(token, options) {
-  var _a;
+  var _a2;
   const key = token.trim().toLowerCase();
-  const override = enforceHouseholdUnitPolicy((_a = options == null ? void 0 : options.unitMap) == null ? void 0 : _a[key], options);
+  const override = enforceHouseholdUnitPolicy((_a2 = options == null ? void 0 : options.unitMap) == null ? void 0 : _a2[key], options);
   if (override) {
     return override;
   }
@@ -14391,8 +14869,80 @@ function normalizeUnit(token, options) {
   if (defaultUnit) {
     return defaultUnit;
   }
+  const terminologyEntry = getDoseUnitTerminologyEntry(token);
+  const terminologyUnit = (terminologyEntry == null ? void 0 : terminologyEntry.parseAsDose) === false ? void 0 : terminologyEntry == null ? void 0 : terminologyEntry.unit;
+  const policyCheckedTerminologyUnit = enforceHouseholdUnitPolicy(terminologyUnit, options);
+  if (policyCheckedTerminologyUnit) {
+    return policyCheckedTerminologyUnit;
+  }
   return void 0;
 }
+function normalizeUnitKey(unit) {
+  const normalized = unit == null ? void 0 : unit.trim();
+  return normalized ? normalized.toLowerCase() : void 0;
+}
+function unitApproximationOverride(unit, context) {
+  const entries = context == null ? void 0 : context.unitApproximationMap;
+  if (!entries) {
+    return void 0;
+  }
+  const unitKey = normalizeUnitKey(unit);
+  for (const candidateUnit in entries) {
+    if (!Object.prototype.hasOwnProperty.call(entries, candidateUnit)) {
+      continue;
+    }
+    const approximation = entries[candidateUnit];
+    if (normalizeUnitKey(candidateUnit) === unitKey) {
+      return approximation;
+    }
+  }
+  return void 0;
+}
+function getDoseUnitTerminologyEntry(unit) {
+  var _a2;
+  if (!unit) {
+    return void 0;
+  }
+  return DOSE_UNIT_TERMINOLOGY_BY_KEY.get((_a2 = normalizeUnitKey(unit)) != null ? _a2 : "");
+}
+function getDoseUnitKind(unit) {
+  var _a2;
+  return (_a2 = getDoseUnitTerminologyEntry(unit)) == null ? void 0 : _a2.kind;
+}
+function getDoseUnitApproximation(unit, context) {
+  var _a2, _b;
+  if (!unit) {
+    return void 0;
+  }
+  const terminologyEntry = getDoseUnitTerminologyEntry(unit);
+  const override = (_b = unitApproximationOverride(unit, context)) != null ? _b : unitApproximationOverride((_a2 = terminologyEntry == null ? void 0 : terminologyEntry.unit) != null ? _a2 : "", context);
+  if (override) {
+    return override;
+  }
+  return terminologyEntry == null ? void 0 : terminologyEntry.approximateQuantity;
+}
+function getDoseUnitSemantics(unit, context) {
+  if (!unit) {
+    return void 0;
+  }
+  const terminologyEntry = getDoseUnitTerminologyEntry(unit);
+  if (!terminologyEntry) {
+    return void 0;
+  }
+  return {
+    unit: terminologyEntry.unit,
+    kind: terminologyEntry.kind,
+    parseAsDose: terminologyEntry.parseAsDose,
+    approximateQuantity: getDoseUnitApproximation(unit, context)
+  };
+}
+function listDoseUnitTerminology() {
+  return DOSE_UNIT_TERMINOLOGY.map((entry) => __spreadProps(__spreadValues({}, entry), {
+    aliases: entry.aliases ? [...entry.aliases] : void 0,
+    parseAsDose: entry.parseAsDose,
+    approximateQuantity: entry.approximateQuantity ? __spreadValues({}, entry.approximateQuantity) : void 0
+  }));
+}
 function enforceHouseholdUnitPolicy(unit, options) {
   if (unit && (options == null ? void 0 : options.allowHouseholdVolumeUnits) === false && HOUSEHOLD_VOLUME_UNIT_SET.has(unit.toLowerCase())) {
     return void 0;
@@ -14403,7 +14953,8 @@ function isDiscreteUnit(unit) {
   if (!unit) {
     return false;
   }
-  return DISCRETE_UNIT_SET.has(unit.trim().toLowerCase());
+  const semantics = getDoseUnitSemantics(unit);
+  return Boolean(semantics && DISCRETE_UNIT_KINDS.has(semantics.kind));
 }
 
 // src/hpsg/method-lexicon.ts
@@ -14412,6 +14963,8 @@ var METHOD_ACTION_BY_VERB = {
   apply: "apply" /* Apply */,
   dab: "apply" /* Apply */,
   drink: "swallow" /* Swallow */,
+  inhale: "inhale" /* Inhale */,
+  inject: "inject" /* Inject */,
   insert: "insert" /* Insert */,
   instill: "instill" /* Instill */,
   lather: "wash" /* Wash */,
@@ -14438,6 +14991,18 @@ var METHOD_CODING_BY_ACTION = {
     display: "Apply",
     _display: buildTranslationPrimitiveElement({ th: "\u0E17\u0E32" })
   },
+  ["inhale" /* Inhale */]: {
+    system: SNOMED_SYSTEM6,
+    code: "740666001",
+    display: "Inhale",
+    _display: buildTranslationPrimitiveElement({ th: "\u0E2A\u0E39\u0E14" })
+  },
+  ["inject" /* Inject */]: {
+    system: SNOMED_SYSTEM6,
+    code: "740685003",
+    display: "Inject",
+    _display: buildTranslationPrimitiveElement({ th: "\u0E09\u0E35\u0E14" })
+  },
   ["insert" /* Insert */]: {
     system: SNOMED_SYSTEM6,
     code: "738993004",
@@ -14483,12 +15048,12 @@ function cloneMethodCoding(coding) {
 
 // src/hpsg/rules/product-route.ts
 function productRouteHint(phrase) {
-  var _a;
+  var _a2;
   const key = (phrase != null ? phrase : "").trim().replace(/\s+/g, " ").toLowerCase();
   if (!key) {
     return void 0;
   }
-  const direct = (_a = PRODUCT_FORM_HINTS[key]) == null ? void 0 : _a.routeHint;
+  const direct = (_a2 = PRODUCT_FORM_HINTS[key]) == null ? void 0 : _a2.routeHint;
   if (direct) {
     return direct;
   }
@@ -14507,23 +15072,23 @@ function isKnownPrnReasonText(text) {
   return Boolean(canonical && DEFAULT_PRN_REASON_DEFINITIONS[canonical]);
 }
 function normalizeLocatedReasonHead(text) {
-  var _a;
+  var _a2;
   const canonical = normalizePrnReasonKey(text);
   if (!canonical) {
     return void 0;
   }
-  return (_a = PRN_GENERIC_LOCATED_HEADS.get(canonical)) != null ? _a : canonical;
+  return (_a2 = PRN_GENERIC_LOCATED_HEADS.get(canonical)) != null ? _a2 : canonical;
 }
 function isLocatedReasonHead(text) {
   const canonical = normalizeLocatedReasonHead(text);
   return Boolean(canonical && (DEFAULT_PRN_REASON_DEFINITIONS[canonical] || PRN_GENERIC_LOCATED_HEADS.has(canonical)));
 }
 function normalizePredicativeReasonText(text) {
-  var _a, _b;
-  return (_b = PRN_PREDICATE_REASON_NORMALIZATIONS.get((_a = normalizePrnReasonKey(text)) != null ? _a : "")) != null ? _b : text;
+  var _a2, _b;
+  return (_b = PRN_PREDICATE_REASON_NORMALIZATIONS.get((_a2 = normalizePrnReasonKey(text)) != null ? _a2 : "")) != null ? _b : text;
 }
 function canStartPrnReasonAtom(context, start) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   const first = context.tokens[start];
   if (!first || context.state.consumed.has(first.index)) {
     return false;
@@ -14547,7 +15112,7 @@ function canStartPrnReasonAtom(context, start) {
       return true;
     }
   }
-  const resolvedSite = resolveBodySitePhrase(first.original, (_a = context.options) == null ? void 0 : _a.siteCodeMap, {
+  const resolvedSite = resolveBodySitePhrase(first.original, (_a2 = context.options) == null ? void 0 : _a2.siteCodeMap, {
     bodySiteContext: (_c = (_b = context.options) == null ? void 0 : _b.context) == null ? void 0 : _c.bodySiteContext
   });
   return Boolean((resolvedSite == null ? void 0 : resolvedSite.coding) || (resolvedSite == null ? void 0 : resolvedSite.definition));
@@ -14570,7 +15135,7 @@ function canContinuePrnReasonAfterSeparator(context, index) {
   return false;
 }
 function startsDosageSiteComplement(context, start) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   const anchor = context.tokens[start];
   if (!anchor || !PRN_CONDITIONAL_SITE_BOUNDARY_ANCHORS.has(normalizeTokenLower(anchor))) {
     return false;
@@ -14589,7 +15154,7 @@ function startsDosageSiteComplement(context, start) {
       displayTokens.push(token);
     }
     const sourceText = joinTokenText(displayTokens).replace(/[{}]/g, "").trim();
-    if (sourceText && resolveBodySitePhrase(sourceText, (_a = context.options) == null ? void 0 : _a.siteCodeMap, {
+    if (sourceText && resolveBodySitePhrase(sourceText, (_a2 = context.options) == null ? void 0 : _a2.siteCodeMap, {
       bodySiteContext: (_c = (_b = context.options) == null ? void 0 : _b.context) == null ? void 0 : _c.bodySiteContext
     })) {
       return true;
@@ -14618,7 +15183,7 @@ function splitPrnReasonParts(tokens) {
   return parts;
 }
 function createPrnReasonRequest(context, text, tokens, headText, siteText) {
-  var _a, _b, _c, _d, _e, _f, _g, _h;
+  var _a2, _b, _c, _d, _e, _f, _g, _h;
   const range = rangeFromTokens(tokens);
   const rawText = joinTokenText(tokens);
   const isProbe = rawText.includes("{") || rawText.includes("}");
@@ -14626,7 +15191,7 @@ function createPrnReasonRequest(context, text, tokens, headText, siteText) {
   if (isProbe && range) {
     let start = range.start;
     let end = range.end;
-    while (start < end && /[\s{]/.test((_a = context.state.input[start]) != null ? _a : "")) {
+    while (start < end && /[\s{]/.test((_a2 = context.state.input[start]) != null ? _a2 : "")) {
       start += 1;
     }
     while (end > start && /[\s}]/.test((_b = context.state.input[end - 1]) != null ? _b : "")) {
@@ -14668,7 +15233,7 @@ function createPrnReasonRequest(context, text, tokens, headText, siteText) {
   };
 }
 function parseLocatedPrnAtom(context, tokens, previousLocatedHead, options) {
-  var _a, _b, _c, _d, _e, _f, _g, _h, _i;
+  var _a2, _b, _c, _d, _e, _f, _g, _h, _i;
   const directText = joinTokenText(tokens);
   const cleanDirectText = directText.replace(/[{}]/g, "").replace(/\s+/g, " ").trim();
   if (!cleanDirectText) {
@@ -14693,7 +15258,7 @@ function parseLocatedPrnAtom(context, tokens, previousLocatedHead, options) {
     const headText = joinTokenText(tokens.slice(0, index));
     const normalizedHead = normalizePredicativeReasonText(headText);
     const siteText = joinTokenText(tokens.slice(index));
-    if (isLocatedReasonHead(normalizedHead) && resolveBodySitePhrase(siteText, (_a = context.options) == null ? void 0 : _a.siteCodeMap, {
+    if (isLocatedReasonHead(normalizedHead) && resolveBodySitePhrase(siteText, (_a2 = context.options) == null ? void 0 : _a2.siteCodeMap, {
       bodySiteContext: (_c = (_b = context.options) == null ? void 0 : _b.context) == null ? void 0 : _c.bodySiteContext
     })) {
       return createPrnReasonRequest(context, cleanDirectText, tokens, normalizedHead, siteText);
@@ -14745,8 +15310,8 @@ function parsePrnReasonAtoms(context, reasonTokens, options) {
 }
 function prnLexicalRule() {
   return lexicalRule("hpsg.lex.prn", (context, start) => {
-    var _a, _b;
-    const lead = (_a = tokensAvailable(context, start, 1)) == null ? void 0 : _a[0];
+    var _a2, _b;
+    const lead = (_a2 = tokensAvailable(context, start, 1)) == null ? void 0 : _a2[0];
     if (!lead) {
       return [];
     }
@@ -14860,7 +15425,7 @@ function prnLexicalRule() {
 var INSTRUCTION_PREDICATES = ["take", "apply", "use"];
 function workflowLexicalRule() {
   return lexicalRule("hpsg.lex.patientInstruction.workflow", (context, start) => {
-    var _a, _b;
+    var _a2, _b;
     let cursor = start;
     const consumed = [];
     while (cursor < context.limit) {
@@ -14900,7 +15465,7 @@ function workflowLexicalRule() {
       if (bodyTokens.length && isInstructionSeparator(token)) {
         break;
       }
-      if (bodyTokens.length && isScheduleLead(context, cursor) && !(((_a = bodyTokens[bodyTokens.length - 1]) == null ? void 0 : _a.kind) === "NUMBER" /* Number */ && mapIntervalUnit(lower)) && !WORKFLOW_CONTINUATION_LICENSES.has(`${previousLower} ${lower}`) && !(previousLower && WORKFLOW_CONTINUATION_LICENSES.has(`${previousLower} *event`) && EVENT_TIMING_TOKENS[lower]) && !WORKFLOW_CONTINUATION_LICENSES.has(`${lower} ${nextLower}`)) {
+      if (bodyTokens.length && isScheduleLead(context, cursor) && !(((_a2 = bodyTokens[bodyTokens.length - 1]) == null ? void 0 : _a2.kind) === "NUMBER" /* Number */ && mapIntervalUnit(lower)) && !WORKFLOW_CONTINUATION_LICENSES.has(`${previousLower} ${lower}`) && !(previousLower && WORKFLOW_CONTINUATION_LICENSES.has(`${previousLower} *event`) && EVENT_TIMING_TOKENS[lower]) && !WORKFLOW_CONTINUATION_LICENSES.has(`${lower} ${nextLower}`)) {
         break;
       }
       if (LIST_SEPARATORS.has(lower) && bodyTokens.length && !WORKFLOW_NOUNS.has(normalizeTokenLower((_b = context.tokens[cursor + 1]) != null ? _b : token))) {
@@ -14961,8 +15526,8 @@ function parseInstructionCandidates(text, range) {
     }));
     const score = instructions.reduce(
       (sum, instruction) => {
-        var _a, _b;
-        return sum + (((_a = instruction.coding) == null ? void 0 : _a.code) ? 4 : 0) + (((_b = instruction.frames) == null ? void 0 : _b.length) ? 2 : 0) + (instruction.text ? 1 : 0);
+        var _a2, _b;
+        return sum + (((_a2 = instruction.coding) == null ? void 0 : _a2.code) ? 4 : 0) + (((_b = instruction.frames) == null ? void 0 : _b.length) ? 2 : 0) + (instruction.text ? 1 : 0);
       },
       0
     );
@@ -14973,6 +15538,23 @@ function parseInstructionCandidates(text, range) {
   }
   return best;
 }
+function bodyParsesAsStyleInstruction(context, bodyTokens) {
+  const range = rangeFromTokens(bodyTokens);
+  const text = range ? context.state.input.slice(range.start, range.end).replace(/\s+/g, " ").trim() : joinTokenText(bodyTokens);
+  if (!range || !text) {
+    return false;
+  }
+  return parseInstructionCandidates(text, range).some(
+    (instruction) => {
+      var _a2;
+      return (_a2 = instruction.frames) == null ? void 0 : _a2.some(
+        (frame) => !frame.relation && frame.predicate.semanticClass === "administration" && frame.args.length > 0 && frame.args.every(
+          (arg) => arg.role === "amount" /* Amount */ || arg.role === "free" /* Free */
+        )
+      );
+    }
+  );
+}
 function instructionLexicalRule() {
   return lexicalRule("hpsg.lex.instruction", (context, start) => {
     const first = context.tokens[start];
@@ -15007,6 +15589,9 @@ function instructionLexicalRule() {
       if (bodyTokens.length && isScheduleLead(context, cursor)) {
         break;
       }
+      if (bodyTokens.length && SITE_ANCHORS.has(normalizeTokenLower(token)) && bodyParsesAsStyleInstruction(context, bodyTokens)) {
+        break;
+      }
       bodyTokens.push(token);
     }
     if (!bodyTokens.length) {
@@ -15023,8 +15608,8 @@ function instructionLexicalRule() {
     }
     const hasStructuredInstruction = instructions.some(
       (instruction) => {
-        var _a, _b;
-        return ((_a = instruction.coding) == null ? void 0 : _a.code) || ((_b = instruction.frames) == null ? void 0 : _b.length);
+        var _a2, _b;
+        return ((_a2 = instruction.coding) == null ? void 0 : _a2.code) || ((_b = instruction.frames) == null ? void 0 : _b.length);
       }
     );
     if (!hasStructuredInstruction && !consumed.length) {
@@ -15048,12 +15633,12 @@ function instructionLexicalRule() {
 
 // src/context.ts
 function normalizeDosageForm(form) {
-  var _a;
+  var _a2;
   if (!form) {
     return void 0;
   }
   const key = form.trim().toLowerCase();
-  return (_a = KNOWN_DOSAGE_FORMS_TO_DOSE[key]) != null ? _a : key;
+  return (_a2 = KNOWN_DOSAGE_FORMS_TO_DOSE[key]) != null ? _a2 : key;
 }
 function inferUnitFromContext(ctx) {
   if (!ctx) {
@@ -15077,7 +15662,7 @@ function inferUnitFromContext(ctx) {
   return void 0;
 }
 function inferRouteFromContext(ctx) {
-  var _a;
+  var _a2;
   if (!(ctx == null ? void 0 : ctx.dosageForm)) {
     return void 0;
   }
@@ -15087,29 +15672,29 @@ function inferRouteFromContext(ctx) {
   }
   const snomed = KNOWN_TMT_DOSAGE_FORM_TO_SNOMED_ROUTE[normalized];
   if (!snomed) {
-    return (_a = DEFAULT_ROUTE_SYNONYMS[normalized]) == null ? void 0 : _a.code;
+    return (_a2 = DEFAULT_ROUTE_SYNONYMS[normalized]) == null ? void 0 : _a2.code;
   }
   return ROUTE_BY_SNOMED[snomed];
 }
 
 // src/hpsg/rules/site-rules.ts
 function siteBoundary(lower, context) {
-  var _a, _b, _c;
-  const siteLike = Boolean(resolveBodySitePhrase(lower, (_a = context.options) == null ? void 0 : _a.siteCodeMap, {
+  var _a2, _b, _c;
+  const siteLike = Boolean(resolveBodySitePhrase(lower, (_a2 = context.options) == null ? void 0 : _a2.siteCodeMap, {
     bodySiteContext: (_c = (_b = context.options) == null ? void 0 : _b.context) == null ? void 0 : _c.bodySiteContext
   }));
-  return isPunctuation(lower) || PRN_LEADS.has(lower) || PRN_STANDALONE_REASON_LEADS.has(lower) || DURATION_LEAD_TOKENS.has(lower) || Boolean(
-    METHOD_ACTION_BY_VERB[lower] || DEFAULT_ROUTE_SYNONYMS[lower] && !siteLike || productRouteHint(lower) || normalizeUnit(lower, context.options) || TIMING_ABBREVIATIONS[lower] || WORD_FREQUENCIES[lower] || FREQUENCY_SIMPLE_WORDS[lower] !== void 0 || FREQUENCY_NUMBER_WORDS[lower] !== void 0 || FREQUENCY_TIMES_WORDS.has(lower) || EVENT_TIMING_TOKENS[lower] || isClockLikeLower(lower) || isAmPmLower(lower) || EVERY_INTERVAL_TOKENS.has(lower) || mapFrequencyAdverb(lower) || mapIntervalUnit(lower)
+  return isPunctuation(lower) || PRN_LEADS.has(lower) || PRN_STANDALONE_REASON_LEADS.has(lower) || DURATION_LEAD_TOKENS.has(lower) || SITE_TRAILING_INSTRUCTION_WORDS.has(lower) || Boolean(
+    METHOD_ACTION_BY_VERB[lower] || DEFAULT_ROUTE_SYNONYMS[lower] && !siteLike || productRouteHint(lower) || normalizeUnit(lower, context.options) && !siteLike || TIMING_ABBREVIATIONS[lower] || WORD_FREQUENCIES[lower] || FREQUENCY_SIMPLE_WORDS[lower] !== void 0 || FREQUENCY_NUMBER_WORDS[lower] !== void 0 || FREQUENCY_TIMES_WORDS.has(lower) || EVENT_TIMING_TOKENS[lower] || isClockLikeLower(lower) || isAmPmLower(lower) || EVERY_INTERVAL_TOKENS.has(lower) || mapFrequencyAdverb(lower) || mapIntervalUnit(lower)
   );
 }
 function trimBraceRange(input, range) {
-  var _a, _b;
+  var _a2, _b;
   if (!range) {
     return void 0;
   }
   let start = range.start;
   let end = range.end;
-  while (start < end && /[\s{}]/.test((_a = input[start]) != null ? _a : "")) {
+  while (start < end && /[\s{}]/.test((_a2 = input[start]) != null ? _a2 : "")) {
     start += 1;
   }
   while (end > start && /[\s{}]/.test((_b = input[end - 1]) != null ? _b : "")) {
@@ -15146,8 +15731,8 @@ function hasSystemicCueBeforeSiteAbbreviation(context, start) {
   return sawNonOcularDose;
 }
 function contextSuggestsNonOcularSite(context) {
-  var _a, _b, _c, _d, _e, _f;
-  const dosageForm = (_c = (_b = (_a = context.options) == null ? void 0 : _a.context) == null ? void 0 : _b.dosageForm) == null ? void 0 : _c.trim().toLowerCase().replace(/\s+/g, " ");
+  var _a2, _b, _c, _d, _e, _f;
+  const dosageForm = (_c = (_b = (_a2 = context.options) == null ? void 0 : _a2.context) == null ? void 0 : _b.dosageForm) == null ? void 0 : _c.trim().toLowerCase().replace(/\s+/g, " ");
   const route = (_f = inferRouteFromContext((_e = (_d = context.options) == null ? void 0 : _d.context) != null ? _e : void 0)) != null ? _f : dosageForm ? productRouteHint(dosageForm) : void 0;
   return Boolean(route && !OCULAR_ROUTE_CODES.has(route));
 }
@@ -15156,8 +15741,8 @@ function shouldSuppressEyeSiteAbbreviation(context, start, lower) {
 }
 function siteLexicalRule() {
   return lexicalRule("hpsg.lex.site", (context, start) => {
-    var _a, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n, _o, _p, _q;
-    const token = (_a = tokensAvailable(context, start, 1)) == null ? void 0 : _a[0];
+    var _a2, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n, _o, _p, _q;
+    const token = (_a2 = tokensAvailable(context, start, 1)) == null ? void 0 : _a2[0];
     if (!token) {
       return [];
     }
@@ -15295,9 +15880,9 @@ function siteLexicalRule() {
 }
 function bareSiteLexicalRule() {
   return lexicalRule("hpsg.lex.site.bare", (context, start) => {
-    var _a, _b, _c, _d, _e, _f, _g, _h;
+    var _a2, _b, _c, _d, _e, _f, _g, _h;
     const signs = [];
-    const first = (_a = tokensAvailable(context, start, 1)) == null ? void 0 : _a[0];
+    const first = (_a2 = tokensAvailable(context, start, 1)) == null ? void 0 : _a2[0];
     if (!first) {
       return [];
     }
@@ -15372,7 +15957,7 @@ function bareSiteLexicalRule() {
 // src/hpsg/rules/core-rules.ts
 function methodLexicalRule() {
   return lexicalRule("hpsg.lex.method", (context, start) => {
-    var _a;
+    var _a2;
     const tokens = tokensAvailable(context, start, 1);
     const token = tokens == null ? void 0 : tokens[0];
     if (!tokens || !token) {
@@ -15383,7 +15968,7 @@ function methodLexicalRule() {
       return [];
     }
     const action = METHOD_ACTION_BY_VERB[verb];
-    const route = (_a = getRouteMeaning(token)) != null ? _a : action === "apply" /* Apply */ ? { code: RouteCode["Topical route"], text: ROUTE_TEXT[RouteCode["Topical route"]] } : void 0;
+    const route = (_a2 = getRouteMeaning(token)) != null ? _a2 : action === "apply" /* Apply */ ? { code: RouteCode["Topical route"], text: ROUTE_TEXT[RouteCode["Topical route"]] } : void 0;
     return [
       lexicalSign({
         type: "method-sign",
@@ -15407,7 +15992,7 @@ function methodLexicalRule() {
 }
 function routeLexicalRule() {
   return lexicalRule("hpsg.lex.route", (context, start) => {
-    var _a;
+    var _a2;
     const signs = [];
     const maxSpan = Math.min(24, context.limit - start);
     for (let span = maxSpan; span >= 1; span -= 1) {
@@ -15424,13 +16009,13 @@ function routeLexicalRule() {
       }
       const routeCandidates = routePhraseCandidates(phrase);
       const customCode = routeCandidates.map((candidate) => {
-        var _a2, _b;
-        return (_b = (_a2 = context.options) == null ? void 0 : _a2.routeMap) == null ? void 0 : _b[candidate];
+        var _a3, _b;
+        return (_b = (_a3 = context.options) == null ? void 0 : _a3.routeMap) == null ? void 0 : _b[candidate];
       }).find((code) => Boolean(code));
       const tokenRoute = span === 1 ? getRouteMeaning(tokens[0]) : void 0;
       const routeFromSitePreposition = routeFromSitePrepositionPhrase(tokens, context);
       const synonym = routeCandidates.map((candidate) => DEFAULT_ROUTE_SYNONYMS[candidate]).find(Boolean);
-      const route = customCode ? { code: customCode, text: ROUTE_TEXT[customCode] } : (_a = tokenRoute != null ? tokenRoute : synonym) != null ? _a : routeFromSitePreposition;
+      const route = customCode ? { code: customCode, text: ROUTE_TEXT[customCode] } : (_a2 = tokenRoute != null ? tokenRoute : synonym) != null ? _a2 : routeFromSitePreposition;
       if (!route) {
         continue;
       }
@@ -15457,7 +16042,7 @@ function routeLexicalRule() {
   });
 }
 function routeTokenIsPartitiveSiteHead(context, start, span) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   if (span !== 1) {
     return false;
   }
@@ -15477,7 +16062,7 @@ function routeTokenIsPartitiveSiteHead(context, start, span) {
     if (tokens.some((token) => context.state.consumed.has(token.index))) {
       return false;
     }
-    const resolved = resolveBodySitePhrase(joinTokenText(tokens), (_a = context.options) == null ? void 0 : _a.siteCodeMap, {
+    const resolved = resolveBodySitePhrase(joinTokenText(tokens), (_a2 = context.options) == null ? void 0 : _a2.siteCodeMap, {
       bodySiteContext: (_c = (_b = context.options) == null ? void 0 : _b.context) == null ? void 0 : _c.bodySiteContext
     });
     if ((resolved == null ? void 0 : resolved.features.kind) === "partitive") {
@@ -15487,12 +16072,12 @@ function routeTokenIsPartitiveSiteHead(context, start, span) {
   return false;
 }
 function routeFromSitePrepositionPhrase(tokens, context) {
-  var _a, _b, _c, _d, _e, _f, _g;
+  var _a2, _b, _c, _d, _e, _f, _g;
   if (tokens.length < 2 || !ROUTE_SITE_PREPOSITIONS.has(normalizeTokenLower(tokens[0]))) {
     return void 0;
   }
   const siteText = tokens.slice(1).map((token) => token.original).join(" ");
-  const resolved = resolveBodySitePhrase(siteText, (_a = context.options) == null ? void 0 : _a.siteCodeMap, {
+  const resolved = resolveBodySitePhrase(siteText, (_a2 = context.options) == null ? void 0 : _a2.siteCodeMap, {
     bodySiteContext: (_c = (_b = context.options) == null ? void 0 : _b.context) == null ? void 0 : _c.bodySiteContext
   });
   const routeHint = (_g = (_d = resolved == null ? void 0 : resolved.definition) == null ? void 0 : _d.routeHint) != null ? _g : (_f = DEFAULT_BODY_SITE_SNOMED[(_e = resolved == null ? void 0 : resolved.canonical) != null ? _e : ""]) == null ? void 0 : _f.routeHint;
@@ -15513,8 +16098,8 @@ function routePhraseCandidates(phrase) {
 }
 function fillerLexicalRule() {
   return lexicalRule("hpsg.lex.filler.medicationObject", (context, start) => {
-    var _a;
-    const token = (_a = tokensAvailable(context, start, 1)) == null ? void 0 : _a[0];
+    var _a2;
+    const token = (_a2 = tokensAvailable(context, start, 1)) == null ? void 0 : _a2[0];
     if (!token || !MEDICATION_OBJECT_FILLERS.has(normalizeTokenLower(token))) {
       return [];
     }
@@ -15531,7 +16116,7 @@ function fillerLexicalRule() {
 }
 function productLexicalRule() {
   return lexicalRule("hpsg.lex.product", (context, start) => {
-    var _a;
+    var _a2;
     const signs = [];
     const maxSpan = Math.min(4, context.limit - start);
     for (let span = maxSpan; span >= 1; span -= 1) {
@@ -15549,7 +16134,7 @@ function productLexicalRule() {
       }
       const previous = context.tokens[start - 1];
       const previousVerb = previous && METHOD_ACTION_BY_VERB[normalizeTokenLower(previous)] ? normalizeTokenLower(previous) : void 0;
-      const methodText = previousVerb ? (_a = PRODUCT_METHOD_TEXT[previousVerb]) == null ? void 0 : _a[phrase] : void 0;
+      const methodText = previousVerb ? (_a2 = PRODUCT_METHOD_TEXT[previousVerb]) == null ? void 0 : _a2[phrase] : void 0;
       signs.push(
         lexicalSign({
           type: "phrase-sign",
@@ -15574,21 +16159,53 @@ function productLexicalRule() {
     return signs;
   });
 }
+function matchCompoundDoseUnit(context, start, lower) {
+  var _a2;
+  for (const compound of COMPOUND_DOSE_UNITS) {
+    if (compound.head !== lower) {
+      continue;
+    }
+    const sequences = (_a2 = compound.tailSequences) != null ? _a2 : [];
+    for (const sequence of sequences) {
+      const matchedTokens = [];
+      let matched = true;
+      for (let offset = 0; offset < sequence.length; offset += 1) {
+        const candidate = context.tokens[start + 1 + offset];
+        if (!candidate || context.state.consumed.has(candidate.index) || normalizeTokenLower(candidate) !== sequence[offset]) {
+          matched = false;
+          break;
+        }
+        matchedTokens.push(candidate);
+      }
+      if (matched) {
+        const head = context.tokens[start];
+        return head ? { unit: compound.unit, tokens: [head, ...matchedTokens] } : void 0;
+      }
+    }
+    const next = context.tokens[start + 1];
+    if (next && !context.state.consumed.has(next.index)) {
+      const nextLower = normalizeTokenLower(next);
+      if (compound.tails.indexOf(nextLower) !== -1) {
+        const head = context.tokens[start];
+        return head ? { unit: compound.unit, tokens: [head, next] } : void 0;
+      }
+    }
+  }
+  return void 0;
+}
 function unitAfter(context, start) {
   const token = context.tokens[start];
   if (!token || context.state.consumed.has(token.index)) {
     return void 0;
   }
   const lower = normalizeTokenLower(token);
-  const compound = COMPOUND_DOSE_UNITS.find((entry) => entry.head === lower);
+  if (DOSE_UNIT_CONNECTORS.has(lower)) {
+    const nested = unitAfter(context, start + 1);
+    return nested ? { unit: nested.unit, tokens: [token, ...nested.tokens] } : void 0;
+  }
+  const compound = matchCompoundDoseUnit(context, start, lower);
   if (compound) {
-    const next = context.tokens[start + 1];
-    if (next && !context.state.consumed.has(next.index)) {
-      const nextLower = normalizeTokenLower(next);
-      if (compound.tails.indexOf(nextLower) !== -1) {
-        return { unit: compound.unit, tokens: [token, next] };
-      }
-    }
+    return compound;
   }
   const direct = normalizeUnit(lower, context.options);
   if (direct) {
@@ -15596,6 +16213,48 @@ function unitAfter(context, start) {
   }
   return void 0;
 }
+function doseNumeratorValue(token, lower) {
+  if (token.kind === "NUMBER" /* Number */ && token.value !== void 0) {
+    return token.value;
+  }
+  return DOSE_NUMBER_WORDS.get(lower);
+}
+function percentBodyAreaDoseAfter(context, start, lower) {
+  const percentMatch = lower.match(/^([0-9]+(?:\.[0-9]+)?)%$/);
+  if (!percentMatch) {
+    return void 0;
+  }
+  const unitToken = context.tokens[start + 1];
+  if (!unitToken || context.state.consumed.has(unitToken.index)) {
+    return void 0;
+  }
+  const unit = PERCENT_BODY_AREA_UNITS.get(normalizeTokenLower(unitToken));
+  if (!unit) {
+    return void 0;
+  }
+  const token = context.tokens[start];
+  if (!token) {
+    return void 0;
+  }
+  return [
+    lexicalSign({
+      type: "dose-sign",
+      rule: "hpsg.lex.dose.percentBodyArea",
+      tokens: [token, unitToken],
+      synsem: {
+        head: {
+          dose: {
+            value: parseFloat(percentMatch[1]),
+            unit
+          }
+        },
+        valence: {},
+        cont: { clauseKind: "administration" }
+      },
+      score: 10
+    })
+  ];
+}
 function doseLexicalRule() {
   return lexicalRule("hpsg.lex.dose", (context, start) => {
     const tokens = tokensAvailable(context, start, 1);
@@ -15607,6 +16266,35 @@ function doseLexicalRule() {
     if (isClockDoseContext(context, start, lower)) {
       return [];
     }
+    const percentBodyAreaDose = percentBodyAreaDoseAfter(context, start, lower);
+    if (percentBodyAreaDose) {
+      return percentBodyAreaDose;
+    }
+    const numerator = doseNumeratorValue(token, lower);
+    const denominatorToken = context.tokens[start + 1];
+    const denominatorLower = denominatorToken && !context.state.consumed.has(denominatorToken.index) ? normalizeTokenLower(denominatorToken) : void 0;
+    const denominator = denominatorLower ? DOSE_FRACTION_DENOMINATOR_WORDS.get(denominatorLower) : void 0;
+    if (numerator !== void 0 && denominatorToken && denominator !== void 0) {
+      const unit2 = unitAfter(context, start + 2);
+      return [
+        lexicalSign({
+          type: "dose-sign",
+          rule: "hpsg.lex.dose.wordFractionNumerator",
+          tokens: unit2 ? [token, denominatorToken, ...unit2.tokens] : [token, denominatorToken],
+          synsem: {
+            head: {
+              dose: {
+                value: numerator * denominator,
+                unit: unit2 == null ? void 0 : unit2.unit
+              }
+            },
+            valence: {},
+            cont: { clauseKind: "administration" }
+          },
+          score: unit2 ? 10 : 5
+        })
+      ];
+    }
     const range = parseNumericRange(lower);
     if (range) {
       const unit2 = unitAfter(context, start + 1);
@@ -15651,6 +16339,49 @@ function doseLexicalRule() {
         })
       ];
     }
+    const wordFraction = DOSE_FRACTION_WORDS.get(lower);
+    if (wordFraction !== void 0) {
+      const unit2 = unitAfter(context, start + 1);
+      return [
+        lexicalSign({
+          type: "dose-sign",
+          rule: "hpsg.lex.dose.wordFraction",
+          tokens: unit2 ? [...tokens, ...unit2.tokens] : tokens,
+          synsem: {
+            head: {
+              dose: {
+                value: wordFraction,
+                unit: unit2 == null ? void 0 : unit2.unit
+              }
+            },
+            valence: {},
+            cont: { clauseKind: "administration" }
+          },
+          score: unit2 ? 9 : 4
+        })
+      ];
+    }
+    const implicitUnit = unitAfter(context, start);
+    if (implicitUnit && IMPLICIT_SINGLE_DOSE_UNITS.has(implicitUnit.unit)) {
+      return [
+        lexicalSign({
+          type: "dose-sign",
+          rule: "hpsg.lex.dose.implicitSingleUnit",
+          tokens: implicitUnit.tokens,
+          synsem: {
+            head: {
+              dose: {
+                value: 1,
+                unit: implicitUnit.unit
+              }
+            },
+            valence: {},
+            cont: { clauseKind: "administration" }
+          },
+          score: 9
+        })
+      ];
+    }
     if (token.kind !== "NUMBER" /* Number */ || token.value === void 0) {
       const timesMatch = lower.match(/^([0-9]+(?:\.[0-9]+)?)[x*]$/);
       if (!timesMatch) {
@@ -15731,8 +16462,8 @@ function isClockDoseContext(context, start, lower) {
 }
 function connectorLexicalRule() {
   return lexicalRule("hpsg.lex.connector", (context, start) => {
-    var _a;
-    const token = (_a = tokensAvailable(context, start, 1)) == null ? void 0 : _a[0];
+    var _a2;
+    const token = (_a2 = tokensAvailable(context, start, 1)) == null ? void 0 : _a2[0];
     if (!token) {
       return [];
     }
@@ -15785,13 +16516,13 @@ function buildGrammar(context) {
   };
 }
 function hasUsefulAnalysis(sign) {
-  var _a;
+  var _a2;
   if (!sign) {
     return false;
   }
   const { head, valence } = sign.synsem;
   return Boolean(
-    head.method || head.route || head.dose || head.schedule || valence.site || valence.prn || ((_a = valence.instructions) == null ? void 0 : _a.length) || valence.patientInstruction
+    head.method || head.route || head.dose || head.schedule || valence.site || valence.prn || ((_a2 = valence.instructions) == null ? void 0 : _a2.length) || valence.patientInstruction
   );
 }
 function parseHpsgClause(context) {
@@ -15837,7 +16568,7 @@ function applyRouteDefault(state, context, deps) {
   }
 }
 function applyUnitDefault(state, tokens, context, options) {
-  var _a;
+  var _a2;
   if (state.unit !== void 0 || state.dose === void 0 && state.doseRange === void 0) {
     return;
   }
@@ -15852,12 +16583,12 @@ function applyUnitDefault(state, tokens, context, options) {
       return;
     }
   }
-  state.unit = (_a = enforceHouseholdUnitPolicy(inferUnitFromContext(context), options)) != null ? _a : enforceHouseholdUnitPolicy(inferUnitFromRoute(state), options);
+  state.unit = (_a2 = enforceHouseholdUnitPolicy(inferUnitFromContext(context), options)) != null ? _a2 : enforceHouseholdUnitPolicy(inferUnitFromRoute(state), options);
 }
 function applySingleDoseDefault(state, options) {
-  var _a, _b;
+  var _a2, _b;
   if ((options == null ? void 0 : options.assumeSingleDiscreteDose) && state.unit === void 0) {
-    state.unit = (_b = enforceHouseholdUnitPolicy(inferUnitFromContext((_a = options.context) != null ? _a : void 0), options)) != null ? _b : enforceHouseholdUnitPolicy(inferUnitFromRoute(state), options);
+    state.unit = (_b = enforceHouseholdUnitPolicy(inferUnitFromContext((_a2 = options.context) != null ? _a2 : void 0), options)) != null ? _b : enforceHouseholdUnitPolicy(inferUnitFromRoute(state), options);
   }
   if ((options == null ? void 0 : options.assumeSingleDiscreteDose) && state.dose === void 0 && state.doseRange === void 0 && state.unit !== void 0 && isDiscreteUnit(state.unit)) {
     state.dose = 1;
@@ -15871,14 +16602,14 @@ var ROUTE_REDUNDANT_SITE_CODES = {
   [RouteCode["Oral route"]]: /* @__PURE__ */ new Set(["123851003"])
 };
 function applyRouteSiteDefault(state) {
-  var _a, _b, _c, _d, _e, _f, _g, _h, _i;
+  var _a2, _b, _c, _d, _e, _f, _g, _h, _i;
   if (!state.routeCode) {
     return;
   }
   const redundantCodes = ROUTE_REDUNDANT_SITE_CODES[state.routeCode];
   if (state.siteText && redundantCodes) {
     const currentDefinition = DEFAULT_BODY_SITE_SNOMED[state.siteText.trim().toLowerCase()];
-    const currentCode = (_c = (_a = state.siteCoding) == null ? void 0 : _a.code) != null ? _c : (_b = currentDefinition == null ? void 0 : currentDefinition.coding) == null ? void 0 : _b.code;
+    const currentCode = (_c = (_a2 = state.siteCoding) == null ? void 0 : _a2.code) != null ? _c : (_b = currentDefinition == null ? void 0 : currentDefinition.coding) == null ? void 0 : _b.code;
     if (currentCode && redundantCodes.has(currentCode)) {
       state.siteText = void 0;
       state.siteCoding = void 0;
@@ -15913,9 +16644,9 @@ function applyRouteSiteDefault(state) {
   }
 }
 function hasStructuredTiming(state) {
-  var _a;
+  var _a2;
   return Boolean(
-    state.count !== void 0 || state.duration !== void 0 || state.durationMax !== void 0 || state.durationUnit !== void 0 || state.frequency !== void 0 || state.frequencyMax !== void 0 || state.period !== void 0 || state.periodMax !== void 0 || state.periodUnit !== void 0 || state.timingCode !== void 0 || state.dayOfWeek.length || state.when.length || ((_a = state.timeOfDay) == null ? void 0 : _a.length)
+    state.count !== void 0 || state.duration !== void 0 || state.durationMax !== void 0 || state.durationUnit !== void 0 || state.frequency !== void 0 || state.frequencyMax !== void 0 || state.period !== void 0 || state.periodMax !== void 0 || state.periodUnit !== void 0 || state.timingCode !== void 0 || state.dayOfWeek.length || state.when.length || ((_a2 = state.timeOfDay) == null ? void 0 : _a2.length)
   );
 }
 function addWarning(state, warning) {
@@ -16009,10 +16740,10 @@ function normalizedFormSet(values) {
   return result;
 }
 function smartMealExpansionAllowed(state, options) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   const scope = options.smartMealExpansionScope;
   const route = state.routeCode;
-  const dosageForm = normalizeDosageForm((_a = options.context) == null ? void 0 : _a.dosageForm);
+  const dosageForm = normalizeDosageForm((_a2 = options.context) == null ? void 0 : _a2.dosageForm);
   const excludedRoutes = new Set((_b = scope == null ? void 0 : scope.excludeRoutes) != null ? _b : []);
   const includedRoutes = new Set((_c = scope == null ? void 0 : scope.includeRoutes) != null ? _c : []);
   const excludedForms = normalizedFormSet(scope == null ? void 0 : scope.excludeDosageForms);
@@ -16038,8 +16769,8 @@ function mealPair(options) {
   return options.twoPerDayPair === "breakfast+lunch" ? ["CM" /* Breakfast */, "CD" /* Lunch */] : ["CM" /* Breakfast */, "CV" /* Dinner */];
 }
 function relationForContext(options) {
-  var _a;
-  const relation = (_a = options.context) == null ? void 0 : _a.mealRelation;
+  var _a2;
+  const relation = (_a2 = options.context) == null ? void 0 : _a2.mealRelation;
   return relation === "AC" /* Before Meal */ || relation === "PC" /* After Meal */ || relation === "C" /* Meal */ ? relation : "C" /* Meal */;
 }
 function expandRelationByFrequency(relation, frequency, options) {
@@ -16049,13 +16780,13 @@ function expandRelationByFrequency(relation, frequency, options) {
   const baseMeals = frequency === 1 ? ["CM" /* Breakfast */] : frequency === 2 ? [...mealPair(options)] : frequency === 3 ? [...WITH_MEALS] : [...WITH_MEALS, "HS" /* Before Sleep */];
   const related = MEAL_RELATION_CODES[relation];
   return baseMeals.map((meal) => {
-    var _a;
+    var _a2;
     const index = SPECIFIC_MEAL_INDEX[meal];
-    return index === void 0 ? meal : (_a = related[index]) != null ? _a : meal;
+    return index === void 0 ? meal : (_a2 = related[index]) != null ? _a2 : meal;
   });
 }
 function normalizeMealRelations(when, options) {
-  var _a;
+  var _a2;
   let relation;
   for (const code of when) {
     if (code === "AC" /* Before Meal */ || code === "PC" /* After Meal */ || code === "C" /* Meal */) {
@@ -16082,7 +16813,7 @@ function normalizeMealRelations(when, options) {
       continue;
     }
     const index = SPECIFIC_MEAL_INDEX[code];
-    normalized.push(index === void 0 ? code : (_a = related[index]) != null ? _a : code);
+    normalized.push(index === void 0 ? code : (_a2 = related[index]) != null ? _a2 : code);
   }
   return normalized.length ? normalized : when;
 }
@@ -16094,8 +16825,8 @@ function clockMinutes(clock) {
   return parseInt(match[1], 10) * 60 + parseInt(match[2], 10);
 }
 function sortWhenCodes(when, options) {
-  var _a;
-  const clock = __spreadValues(__spreadValues({}, DEFAULT_EVENT_CLOCK), (_a = options == null ? void 0 : options.eventClock) != null ? _a : {});
+  var _a2;
+  const clock = __spreadValues(__spreadValues({}, DEFAULT_EVENT_CLOCK), (_a2 = options == null ? void 0 : options.eventClock) != null ? _a2 : {});
   return when.map((code, index) => ({ code, index })).sort((left, right) => {
     const diff = clockMinutes(clock[left.code]) - clockMinutes(clock[right.code]);
     return diff || left.index - right.index;
@@ -16151,15 +16882,15 @@ function applySmartMealExpansion(state, options) {
   replaceWhen(state, sortWhenCodes(uniqueWhen(normalizeMealRelations(when, options)), options));
 }
 function applyWeeklyDefaultForDayFilters(state) {
-  var _a;
-  if (state.dayOfWeek.length && state.frequency === void 0 && state.frequencyMax === void 0 && state.period === void 0 && state.periodMax === void 0 && state.periodUnit === void 0 && !state.when.length && !((_a = state.timeOfDay) == null ? void 0 : _a.length)) {
+  var _a2;
+  if (state.dayOfWeek.length && state.frequency === void 0 && state.frequencyMax === void 0 && state.period === void 0 && state.periodMax === void 0 && state.periodUnit === void 0 && !state.when.length && !((_a2 = state.timeOfDay) == null ? void 0 : _a2.length)) {
     state.period = 1;
     state.periodUnit = "wk" /* Week */;
   }
 }
 function applyHpsgDefaultConstraints(state, tokens, options, deps) {
-  var _a;
-  const context = (_a = options == null ? void 0 : options.context) != null ? _a : void 0;
+  var _a2;
+  const context = (_a2 = options == null ? void 0 : options.context) != null ? _a2 : void 0;
   applyRouteDefault(state, context, deps);
   applyUnitDefault(state, tokens, context, options);
   applySingleDoseDefault(state, options);
@@ -16179,15 +16910,15 @@ function pushUniqueCanonical(canonicals, value) {
   canonicals.push(normalized);
 }
 function pushUniqueCoding(codings, coding) {
-  var _a;
+  var _a2;
   if (!(coding == null ? void 0 : coding.code)) {
     return;
   }
-  const system = (_a = coding.system) != null ? _a : SNOMED_SYSTEM7;
+  const system = (_a2 = coding.system) != null ? _a2 : SNOMED_SYSTEM7;
   if (codings.some(
     (candidate) => {
-      var _a2;
-      return candidate.code === coding.code && ((_a2 = candidate.system) != null ? _a2 : SNOMED_SYSTEM7) === system;
+      var _a3;
+      return candidate.code === coding.code && ((_a3 = candidate.system) != null ? _a3 : SNOMED_SYSTEM7) === system;
     }
   )) {
     return;
@@ -16224,10 +16955,10 @@ function pushResolvedSite(canonicals, codings, value) {
   pushSpatialRelationTarget(canonicals, codings, resolvedSite.spatialRelation);
 }
 function collectParsedBodySiteCandidates(internal) {
-  var _a, _b, _c, _d;
+  var _a2, _b, _c, _d;
   const canonicals = [];
   const codings = [];
-  const normalizedSiteText = normalizeBodySiteKey((_a = internal.siteText) != null ? _a : "");
+  const normalizedSiteText = normalizeBodySiteKey((_a2 = internal.siteText) != null ? _a2 : "");
   const siteCodingDisplay = (_b = internal.siteCoding) == null ? void 0 : _b.display;
   const normalizedSiteCodingDisplay = siteCodingDisplay ? normalizeBodySiteKey(siteCodingDisplay) : "";
   pushResolvedSite(
@@ -16300,8 +17031,8 @@ function collectPrnReasonLookupCanonicals(request) {
   return canonicals;
 }
 function buildPostcoordinatedPrnReasonDefinition(request, definition, hasExactCombinedDefinition) {
-  var _a, _b;
-  if (hasExactCombinedDefinition || !((_a = definition == null ? void 0 : definition.coding) == null ? void 0 : _a.code) || hasSnomedFindingSitePostcoordination(definition.coding.code) || !request.headCanonical || !((_b = request.locativeSiteCoding) == null ? void 0 : _b.code)) {
+  var _a2, _b;
+  if (hasExactCombinedDefinition || !((_a2 = definition == null ? void 0 : definition.coding) == null ? void 0 : _a2.code) || hasSnomedFindingSitePostcoordination(definition.coding.code) || !request.headCanonical || !((_b = request.locativeSiteCoding) == null ? void 0 : _b.code)) {
     return definition;
   }
   const coding = buildSnomedFindingSiteCoding({
@@ -16431,12 +17162,12 @@ function pickPrnReasonSelection(selections, request) {
   return void 0;
 }
 function applyPrnReasonDefinition(internal, definition) {
-  var _a;
+  var _a2;
   const coding = definition.coding;
   internal.asNeededReasonCoding = (coding == null ? void 0 : coding.code) ? {
     code: coding.code,
     display: coding.display,
-    system: (_a = coding.system) != null ? _a : SNOMED_SYSTEM8,
+    system: (_a2 = coding.system) != null ? _a2 : SNOMED_SYSTEM8,
     extension: cloneExtensions(coding.extension),
     i18n: definition == null ? void 0 : definition.i18n
   } : void 0;
@@ -16563,7 +17294,7 @@ function splitCoordinatedPrnReasonText(text) {
   return void 0;
 }
 function maybeApplyCoordinatedPrnReasonsSync(internal, options) {
-  var _a, _b;
+  var _a2, _b;
   const text = internal.asNeededReason;
   if (!text || internal.asNeededReasonCoding) {
     return;
@@ -16578,7 +17309,7 @@ function maybeApplyCoordinatedPrnReasonsSync(internal, options) {
     const definition = resolvePrnReasonDefinitionSyncForRequest(internal, request, options);
     reasons.push({
       text: part,
-      coding: ((_a = definition == null ? void 0 : definition.coding) == null ? void 0 : _a.code) ? {
+      coding: ((_a2 = definition == null ? void 0 : definition.coding) == null ? void 0 : _a2.code) ? {
         code: definition.coding.code,
         display: definition.coding.display,
         system: (_b = definition.coding.system) != null ? _b : SNOMED_SYSTEM8,
@@ -16591,7 +17322,7 @@ function maybeApplyCoordinatedPrnReasonsSync(internal, options) {
 }
 function maybeApplyCoordinatedPrnReasonsAsync(internal, options) {
   return __async(this, null, function* () {
-    var _a, _b;
+    var _a2, _b;
     const text = internal.asNeededReason;
     if (!text || internal.asNeededReasonCoding) {
       return;
@@ -16606,7 +17337,7 @@ function maybeApplyCoordinatedPrnReasonsAsync(internal, options) {
       const definition = yield resolvePrnReasonDefinitionAsyncForRequest(internal, request, options);
       reasons.push({
         text: part,
-        coding: ((_a = definition == null ? void 0 : definition.coding) == null ? void 0 : _a.code) ? {
+        coding: ((_a2 = definition == null ? void 0 : definition.coding) == null ? void 0 : _a2.code) ? {
           code: definition.coding.code,
           display: definition.coding.display,
           system: (_b = definition.coding.system) != null ? _b : SNOMED_SYSTEM8,
@@ -16619,11 +17350,11 @@ function maybeApplyCoordinatedPrnReasonsAsync(internal, options) {
   });
 }
 function uniquePrnReasonRequests(requests) {
-  var _a, _b, _c, _d;
+  var _a2, _b, _c, _d;
   const result = [];
   const seen = /* @__PURE__ */ new Set();
   for (const request of requests != null ? requests : []) {
-    const key = `${(_b = (_a = request.range) == null ? void 0 : _a.start) != null ? _b : ""}:${(_d = (_c = request.range) == null ? void 0 : _c.end) != null ? _d : ""}:${request.text}`;
+    const key = `${(_b = (_a2 = request.range) == null ? void 0 : _a2.start) != null ? _b : ""}:${(_d = (_c = request.range) == null ? void 0 : _c.end) != null ? _d : ""}:${request.text}`;
     if (seen.has(key)) {
       continue;
     }
@@ -16633,20 +17364,20 @@ function uniquePrnReasonRequests(requests) {
   return result;
 }
 function codingFromPrnDefinition(definition) {
-  var _a;
+  var _a2;
   const coding = definition == null ? void 0 : definition.coding;
   return (coding == null ? void 0 : coding.code) ? {
     code: coding.code,
     display: coding.display,
-    system: (_a = coding.system) != null ? _a : SNOMED_SYSTEM8,
+    system: (_a2 = coding.system) != null ? _a2 : SNOMED_SYSTEM8,
     extension: cloneExtensions(coding.extension),
     i18n: definition == null ? void 0 : definition.i18n
   } : void 0;
 }
 function joinPrnReasonTexts(reasons) {
   const texts = reasons.map((reason) => {
-    var _a;
-    return (_a = reason.text) == null ? void 0 : _a.trim();
+    var _a2;
+    return (_a2 = reason.text) == null ? void 0 : _a2.trim();
   }).filter((text) => Boolean(text));
   switch (texts.length) {
     case 0:
@@ -16707,7 +17438,7 @@ function collectSuggestionsForRequestAsync(internal, request, resolution, option
   });
 }
 function runMultiplePrnReasonResolutionSync(internal, requests, options) {
-  var _a;
+  var _a2;
   internal.prnReasonLookups = [];
   internal.asNeeded = true;
   const reasons = [];
@@ -16723,14 +17454,14 @@ function runMultiplePrnReasonResolutionSync(internal, requests, options) {
   internal.asNeededReasons = reasons;
   internal.asNeededReason = joinPrnReasonTexts(reasons);
   if (reasons.length === 1) {
-    internal.asNeededReasonCoding = (_a = reasons[0]) == null ? void 0 : _a.coding;
+    internal.asNeededReasonCoding = (_a2 = reasons[0]) == null ? void 0 : _a2.coding;
   } else {
     internal.asNeededReasonCoding = void 0;
   }
 }
 function runMultiplePrnReasonResolutionAsync(internal, requests, options) {
   return __async(this, null, function* () {
-    var _a;
+    var _a2;
     internal.prnReasonLookups = [];
     internal.asNeeded = true;
     const reasons = [];
@@ -16746,16 +17477,16 @@ function runMultiplePrnReasonResolutionAsync(internal, requests, options) {
     internal.asNeededReasons = reasons;
     internal.asNeededReason = joinPrnReasonTexts(reasons);
     if (reasons.length === 1) {
-      internal.asNeededReasonCoding = (_a = reasons[0]) == null ? void 0 : _a.coding;
+      internal.asNeededReasonCoding = (_a2 = reasons[0]) == null ? void 0 : _a2.coding;
     } else {
       internal.asNeededReasonCoding = void 0;
     }
   });
 }
 function definitionToPrnSuggestion(definition) {
-  var _a, _b, _c, _d;
+  var _a2, _b, _c, _d;
   return {
-    coding: ((_a = definition.coding) == null ? void 0 : _a.code) ? {
+    coding: ((_a2 = definition.coding) == null ? void 0 : _a2.code) ? {
       code: definition.coding.code,
       display: definition.coding.display,
       system: (_b = definition.coding.system) != null ? _b : SNOMED_SYSTEM8,
@@ -16765,12 +17496,12 @@ function definitionToPrnSuggestion(definition) {
   };
 }
 function addReasonSuggestionToMap(map, suggestion) {
-  var _a;
+  var _a2;
   if (!suggestion) {
     return;
   }
   const coding = suggestion.coding;
-  const key = (coding == null ? void 0 : coding.code) ? `${(_a = coding.system) != null ? _a : SNOMED_SYSTEM8}|${coding.code}` : suggestion.text ? `text:${suggestion.text.toLowerCase()}` : void 0;
+  const key = (coding == null ? void 0 : coding.code) ? `${(_a2 = coding.system) != null ? _a2 : SNOMED_SYSTEM8}|${coding.code}` : suggestion.text ? `text:${suggestion.text.toLowerCase()}` : void 0;
   if (!key || map.has(key)) {
     return;
   }
@@ -16822,7 +17553,7 @@ function collectDefaultPrnReasonDefinitions(request) {
   return Array.from(seen);
 }
 function runPrnReasonResolutionSync(internal, options) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   const requests = uniquePrnReasonRequests(internal.prnReasonLookupRequests);
   if (requests.length) {
     runMultiplePrnReasonResolutionSync(internal, requests, options);
@@ -16836,7 +17567,7 @@ function runPrnReasonResolutionSync(internal, options) {
   const canonicals = collectPrnReasonLookupCanonicals(request);
   const combinedCanonical = buildCombinedPrnReasonCanonical(request);
   const selection = pickPrnReasonSelection(options == null ? void 0 : options.prnReasonSelections, request);
-  const exactCustomDefinition = (_a = lookupPrnReasonDefinition(options == null ? void 0 : options.prnReasonMap, request.canonical)) != null ? _a : lookupPrnReasonDefinition(options == null ? void 0 : options.prnReasonMap, combinedCanonical != null ? combinedCanonical : "");
+  const exactCustomDefinition = (_a2 = lookupPrnReasonDefinition(options == null ? void 0 : options.prnReasonMap, request.canonical)) != null ? _a2 : lookupPrnReasonDefinition(options == null ? void 0 : options.prnReasonMap, combinedCanonical != null ? combinedCanonical : "");
   const customDefinition = lookupPrnReasonDefinition(options == null ? void 0 : options.prnReasonMap, canonicals);
   const inferredDefinition = inferSiteSpecificPrnReasonDefinition(internal, request);
   let resolution = selection != null ? selection : customDefinition;
@@ -16917,7 +17648,7 @@ function runPrnReasonResolutionSync(internal, options) {
 }
 function runPrnReasonResolutionAsync(internal, options) {
   return __async(this, null, function* () {
-    var _a, _b, _c;
+    var _a2, _b, _c;
     const requests = uniquePrnReasonRequests(internal.prnReasonLookupRequests);
     if (requests.length) {
       yield runMultiplePrnReasonResolutionAsync(internal, requests, options);
@@ -16931,7 +17662,7 @@ function runPrnReasonResolutionAsync(internal, options) {
     const canonicals = collectPrnReasonLookupCanonicals(request);
     const combinedCanonical = buildCombinedPrnReasonCanonical(request);
     const selection = pickPrnReasonSelection(options == null ? void 0 : options.prnReasonSelections, request);
-    const exactCustomDefinition = (_a = lookupPrnReasonDefinition(options == null ? void 0 : options.prnReasonMap, request.canonical)) != null ? _a : lookupPrnReasonDefinition(options == null ? void 0 : options.prnReasonMap, combinedCanonical != null ? combinedCanonical : "");
+    const exactCustomDefinition = (_a2 = lookupPrnReasonDefinition(options == null ? void 0 : options.prnReasonMap, request.canonical)) != null ? _a2 : lookupPrnReasonDefinition(options == null ? void 0 : options.prnReasonMap, combinedCanonical != null ? combinedCanonical : "");
     const customDefinition = lookupPrnReasonDefinition(options == null ? void 0 : options.prnReasonMap, canonicals);
     const inferredDefinition = inferSiteSpecificPrnReasonDefinition(internal, request);
     let resolution = selection != null ? selection : customDefinition;
@@ -17215,12 +17946,12 @@ function pickSiteSelection(selections, request) {
   return void 0;
 }
 function applySiteDefinition(internal, definition) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   const coding = definition.coding;
   internal.siteCoding = (coding == null ? void 0 : coding.code) ? {
     code: coding.code,
     display: coding.display,
-    system: (_a = coding.system) != null ? _a : SNOMED_SYSTEM9
+    system: (_a2 = coding.system) != null ? _a2 : SNOMED_SYSTEM9
   } : void 0;
   if (definition.text) {
     internal.siteText = definition.text;
@@ -17234,12 +17965,12 @@ function applySiteDefinition(internal, definition) {
   }
 }
 function definitionToSuggestion(definition, omitRedundantText = false) {
-  var _a, _b;
+  var _a2, _b;
   const coding = definition.coding;
   if (!(coding == null ? void 0 : coding.code)) {
     return void 0;
   }
-  const text = omitRedundantText && definition.text && definition.text.trim().toLowerCase() !== ((_a = coding.display) == null ? void 0 : _a.trim().toLowerCase()) ? definition.text : omitRedundantText ? void 0 : definition.text;
+  const text = omitRedundantText && definition.text && definition.text.trim().toLowerCase() !== ((_a2 = coding.display) == null ? void 0 : _a2.trim().toLowerCase()) ? definition.text : omitRedundantText ? void 0 : definition.text;
   return {
     coding: {
       code: coding.code,
@@ -17250,7 +17981,7 @@ function definitionToSuggestion(definition, omitRedundantText = false) {
   };
 }
 function addSuggestionToMap(map, suggestion) {
-  var _a, _b;
+  var _a2, _b;
   if (!suggestion) {
     return;
   }
@@ -17258,7 +17989,7 @@ function addSuggestionToMap(map, suggestion) {
   if (!(coding == null ? void 0 : coding.code)) {
     return;
   }
-  const key = `${(_a = coding.system) != null ? _a : SNOMED_SYSTEM9}|${coding.code}`;
+  const key = `${(_a2 = coding.system) != null ? _a2 : SNOMED_SYSTEM9}|${coding.code}`;
   if (!map.has(key)) {
     map.set(key, {
       coding: {
@@ -17336,6 +18067,8 @@ var METHOD_TEXT_BY_VERB = {
 var METHOD_THAI_BY_VERB = {
   apply: "\u0E17\u0E32",
   drink: "\u0E23\u0E31\u0E1A\u0E1B\u0E23\u0E30\u0E17\u0E32\u0E19",
+  inhale: "\u0E2A\u0E39\u0E14",
+  inject: "\u0E09\u0E35\u0E14",
   insert: "\u0E2A\u0E2D\u0E14",
   instill: "\u0E2B\u0E22\u0E2D\u0E14",
   spray: "\u0E1E\u0E48\u0E19",
@@ -17347,7 +18080,7 @@ function tokenize(input) {
   return annotateLexTokens(lexInput(input));
 }
 function buildCustomSiteHints(map) {
-  var _a, _b;
+  var _a2, _b;
   if (!map) {
     return void 0;
   }
@@ -17369,7 +18102,7 @@ function buildCustomSiteHints(map) {
       continue;
     }
     push(key);
-    (_a = definition.aliases) == null ? void 0 : _a.forEach(push);
+    (_a2 = definition.aliases) == null ? void 0 : _a2.forEach(push);
     push(definition.text);
     push((_b = definition.coding) == null ? void 0 : _b.display);
   }
@@ -17391,11 +18124,11 @@ function addDayOfWeekList(state, days) {
   }
 }
 function isCompatibleRouteRefinement(current, next) {
-  var _a;
+  var _a2;
   if (current === void 0 || current === next) {
     return true;
   }
-  return Boolean((_a = ROUTE_REFINEMENTS.get(current)) == null ? void 0 : _a.has(next));
+  return Boolean((_a2 = ROUTE_REFINEMENTS.get(current)) == null ? void 0 : _a2.has(next));
 }
 function setRoute(state, code, text) {
   if (!isCompatibleRouteRefinement(state.routeCode, code)) {
@@ -17405,12 +18138,12 @@ function setRoute(state, code, text) {
   state.routeText = text != null ? text : ROUTE_TEXT[code];
 }
 function refreshMethodSurface(state) {
-  var _a;
+  var _a2;
   const verb = state.methodVerb;
   if (!verb) {
     return;
   }
-  state.methodText = (_a = METHOD_TEXT_BY_VERB[verb]) != null ? _a : verb.charAt(0).toUpperCase() + verb.slice(1);
+  state.methodText = (_a2 = METHOD_TEXT_BY_VERB[verb]) != null ? _a2 : verb.charAt(0).toUpperCase() + verb.slice(1);
   const thai = METHOD_THAI_BY_VERB[verb];
   state.methodTextElement = thai ? buildTranslationPrimitiveElement({ th: thai }) : void 0;
 }
@@ -17433,13 +18166,13 @@ function recordEvidence(state, rule, startIndex, endIndex) {
   });
 }
 function computeTrimmedInputRange(input) {
-  var _a;
+  var _a2;
   const start = input.search(/\S/);
   if (start === -1) {
     return void 0;
   }
   let end = input.length;
-  while (end > start && /\s/.test((_a = input[end - 1]) != null ? _a : "")) {
+  while (end > start && /\s/.test((_a2 = input[end - 1]) != null ? _a2 : "")) {
     end -= 1;
   }
   return { start, end };
@@ -17490,11 +18223,11 @@ function collectLeftovers(state) {
   return leftovers;
 }
 function cleanupClause(state) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   const clause = state.primaryClause;
   const schedule = clause.schedule;
   if (schedule) {
-    if (!((_a = schedule.dayOfWeek) == null ? void 0 : _a.length)) delete schedule.dayOfWeek;
+    if (!((_a2 = schedule.dayOfWeek) == null ? void 0 : _a2.length)) delete schedule.dayOfWeek;
     if (!((_b = schedule.when) == null ? void 0 : _b.length)) delete schedule.when;
     if (!((_c = schedule.timeOfDay) == null ? void 0 : _c.length)) delete schedule.timeOfDay;
     if (schedule.count === void 0 && schedule.duration === void 0 && schedule.durationMax === void 0 && schedule.durationUnit === void 0 && schedule.frequency === void 0 && schedule.frequencyMax === void 0 && schedule.period === void 0 && schedule.periodMax === void 0 && schedule.periodUnit === void 0 && schedule.timingCode === void 0 && !schedule.dayOfWeek && !schedule.when && !schedule.timeOfDay) {
@@ -17563,12 +18296,12 @@ function seedKnownRouteFromSurface(state) {
   }
 }
 function seedKnownSiteCoding(state) {
-  var _a, _b;
+  var _a2, _b;
   if (!state.siteText || state.siteCoding) {
     return;
   }
   const definition = DEFAULT_BODY_SITE_SNOMED[normalizeBodySiteKey(state.siteText)];
-  if (!((_a = definition == null ? void 0 : definition.coding) == null ? void 0 : _a.code)) {
+  if (!((_a2 = definition == null ? void 0 : definition.coding) == null ? void 0 : _a2.code)) {
     return;
   }
   state.siteCoding = {
@@ -17634,12 +18367,12 @@ function parsesAsInstructionContinuation(input, tokens, index) {
     allowFreeTextFallback: false
   });
   return instructions.some((instruction) => {
-    var _a;
-    return ((_a = instruction.coding) == null ? void 0 : _a.code) || instruction.frames.length;
+    var _a2;
+    return ((_a2 = instruction.coding) == null ? void 0 : _a2.code) || instruction.frames.length;
   });
 }
 function isCommaClauseBoundary(input, tokens, index) {
-  var _a;
+  var _a2;
   const token = tokens[index];
   if (!token || token.original !== ",") {
     return false;
@@ -17650,7 +18383,7 @@ function isCommaClauseBoundary(input, tokens, index) {
   }
   const lower = next.lower.replace(/[.,;:]/g, "");
   const rawLower = next.lower.replace(/^\.+|\.+$/g, "");
-  const following = (_a = tokens[index + 2]) == null ? void 0 : _a.lower.replace(/^\.+|\.+$/g, "");
+  const following = (_a2 = tokens[index + 2]) == null ? void 0 : _a2.lower.replace(/^\.+|\.+$/g, "");
   if (/^[0-9]{1,2}[:.][0-9]{2}$/.test(rawLower) || /^[0-9]{1,2}$/.test(rawLower) && Boolean(following && MERIDIEM_TOKENS.has(following))) {
     return false;
   }
@@ -17669,7 +18402,7 @@ function isCommaClauseBoundary(input, tokens, index) {
   return true;
 }
 function isSlashClauseBoundary(tokens, index) {
-  var _a;
+  var _a2;
   const token = tokens[index];
   if (!token || token.original !== "/") {
     return false;
@@ -17679,7 +18412,7 @@ function isSlashClauseBoundary(tokens, index) {
     return false;
   }
   const previous = tokens[index - 1];
-  const previousLower = (_a = previous == null ? void 0 : previous.lower.replace(/[.,;:]/g, "")) != null ? _a : "";
+  const previousLower = (_a2 = previous == null ? void 0 : previous.lower.replace(/[.,;:]/g, "")) != null ? _a2 : "";
   const lower = next.lower.replace(/[.,;:]/g, "");
   if (/^\d+(?:\.\d+)?$/.test(previousLower) && /^\d+(?:\.\d+)?$/.test(lower)) {
     return false;
@@ -17687,10 +18420,10 @@ function isSlashClauseBoundary(tokens, index) {
   return /^\d/.test(lower) || CLAUSE_LEAD_WORDS.has(lower);
 }
 function pushSegment(segments, input, start, end) {
-  var _a, _b;
+  var _a2, _b;
   let trimmedStart = start;
   let trimmedEnd = end;
-  while (trimmedStart < trimmedEnd && /\s/.test((_a = input[trimmedStart]) != null ? _a : "")) {
+  while (trimmedStart < trimmedEnd && /\s/.test((_a2 = input[trimmedStart]) != null ? _a2 : "")) {
     trimmedStart += 1;
   }
   while (trimmedEnd > trimmedStart && /\s/.test((_b = input[trimmedEnd - 1]) != null ? _b : "")) {
@@ -17794,7 +18527,7 @@ var DEFAULT_UNIT_ROUTE_ORDER = [
   { unit: "patch", routeCode: RouteCode["Transdermal route"] }
 ];
 var ROUTE_TOKEN_BY_UNIT = (() => {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   const map = /* @__PURE__ */ new Map();
   const assign = (unit, token) => {
     if (!unit || !token) {
@@ -17815,7 +18548,7 @@ var ROUTE_TOKEN_BY_UNIT = (() => {
     if (!unit) {
       continue;
     }
-    const token = (_a = ROUTE_TOKEN_BY_CODE[routeCode]) != null ? _a : ROUTE_TEXT[routeCode];
+    const token = (_a2 = ROUTE_TOKEN_BY_CODE[routeCode]) != null ? _a2 : ROUTE_TEXT[routeCode];
     assign(unit, token);
   }
   for (const preference of DEFAULT_UNIT_ROUTE_ORDER) {
@@ -17949,7 +18682,7 @@ var UNIT_LOOKUP = (() => {
   return { canonicalByKey, variantsByCanonical };
 })();
 function resolveCanonicalUnit(unit) {
-  var _a;
+  var _a2;
   if (!unit) {
     return void 0;
   }
@@ -17957,7 +18690,7 @@ function resolveCanonicalUnit(unit) {
   if (!normalized) {
     return void 0;
   }
-  return (_a = UNIT_LOOKUP.canonicalByKey.get(normalized)) != null ? _a : normalizeSpacing(unit);
+  return (_a2 = UNIT_LOOKUP.canonicalByKey.get(normalized)) != null ? _a2 : normalizeSpacing(unit);
 }
 function normalizeKey(value) {
   return value.trim().toLowerCase();
@@ -17996,8 +18729,8 @@ function removeDashes(value) {
 }
 var UNIT_VARIANT_CACHE = /* @__PURE__ */ new Map();
 function getUnitVariants(unit) {
-  var _a;
-  const canonical = (_a = resolveCanonicalUnit(unit)) != null ? _a : normalizeSpacing(unit);
+  var _a2;
+  const canonical = (_a2 = resolveCanonicalUnit(unit)) != null ? _a2 : normalizeSpacing(unit);
   const normalizedCanonical = normalizeKey(canonical);
   const cached = UNIT_VARIANT_CACHE.get(normalizedCanonical);
   if (cached) {
@@ -18147,11 +18880,11 @@ function tokensMatch(prefixTokens, candidateTokens) {
   return prefixIndex >= prefixTokens.length;
 }
 function buildUnitRoutePairs(contextUnit, options) {
-  var _a, _b;
+  var _a2, _b;
   const pairs = [];
   const seen = /* @__PURE__ */ new Set();
   const addPair = (unit, routeOverride) => {
-    var _a2;
+    var _a3;
     const canonicalUnit = resolveCanonicalUnit(unit);
     if (!canonicalUnit) {
       return;
@@ -18160,7 +18893,7 @@ function buildUnitRoutePairs(contextUnit, options) {
     if ((options == null ? void 0 : options.allowHouseholdVolumeUnits) === false && HOUSEHOLD_VOLUME_UNIT_SET2.has(normalizedUnit)) {
       return;
     }
-    const resolvedRoute = (_a2 = routeOverride != null ? routeOverride : ROUTE_TOKEN_BY_UNIT.get(normalizedUnit)) != null ? _a2 : "po";
+    const resolvedRoute = (_a3 = routeOverride != null ? routeOverride : ROUTE_TOKEN_BY_UNIT.get(normalizedUnit)) != null ? _a3 : "po";
     const cleanRoute = normalizeSpacing(resolvedRoute);
     if (!cleanRoute) {
       return;
@@ -18175,7 +18908,7 @@ function buildUnitRoutePairs(contextUnit, options) {
   };
   addPair(contextUnit);
   for (const preference of DEFAULT_UNIT_ROUTE_ORDER) {
-    const routeToken = (_b = (_a = preference.routeToken) != null ? _a : ROUTE_TOKEN_BY_CODE[preference.routeCode]) != null ? _b : ROUTE_TEXT[preference.routeCode];
+    const routeToken = (_b = (_a2 = preference.routeToken) != null ? _a2 : ROUTE_TOKEN_BY_CODE[preference.routeCode]) != null ? _b : ROUTE_TEXT[preference.routeCode];
     addPair(preference.unit, routeToken);
   }
   return pairs;
@@ -18401,7 +19134,7 @@ function generateCandidateDirections(pairs, doseValues, prnReasons, intervalToke
   return suggestions;
 }
 function matchesPrefix(_candidate, candidateLower, context) {
-  var _a, _b, _c, _d, _e, _f;
+  var _a2, _b, _c, _d, _e, _f;
   if (!context.raw) {
     return true;
   }
@@ -18413,7 +19146,7 @@ function matchesPrefix(_candidate, candidateLower, context) {
   }
   const fingerprint = getCandidateFingerprint(candidateLower);
   if (context.requiresCompact) {
-    const compactCandidate = (_a = fingerprint.compact) != null ? _a : fingerprint.compact = removeWhitespaceCharacters(candidateLower);
+    const compactCandidate = (_a2 = fingerprint.compact) != null ? _a2 : fingerprint.compact = removeWhitespaceCharacters(candidateLower);
     if (compactCandidate.startsWith(context.compact)) {
       return true;
     }
@@ -18488,7 +19221,7 @@ function collectMatchedCandidates(candidates, limit, matcher) {
   return suggestions;
 }
 function buildMealDashCoreVariants(prefixCore) {
-  var _a;
+  var _a2;
   if (!prefixCore.includes("-") || prefixCore.includes("--")) {
     return [];
   }
@@ -18496,7 +19229,7 @@ function buildMealDashCoreVariants(prefixCore) {
   if (slots.length < 2 || slots.length > 4) {
     return [];
   }
-  if (!/^[0-9]+(?:\.[0-9]+)?$/.test((_a = slots[0]) != null ? _a : "")) {
+  if (!/^[0-9]+(?:\.[0-9]+)?$/.test((_a2 = slots[0]) != null ? _a2 : "")) {
     return [];
   }
   for (let i = 1; i < slots.length; i += 1) {
@@ -18569,7 +19302,7 @@ function suggestMealDashSyntax(prefix, limit, matcher) {
   return collectMatchedCandidates(candidates, limit, matcher);
 }
 function suggestCompactOralMealTiming(prefix, limit, matcher) {
-  var _a, _b;
+  var _a2, _b;
   const match = prefix.match(
     /^(\d+(?:\.\d+)?)\s*(?:po\s*(c|ac|pc)|po(c|ac|pc))$/
   );
@@ -18577,14 +19310,14 @@ function suggestCompactOralMealTiming(prefix, limit, matcher) {
     return void 0;
   }
   const dose = normalizeSpacing(match[1]);
-  const timing = ((_b = (_a = match[2]) != null ? _a : match[3]) != null ? _b : "").toLowerCase();
+  const timing = ((_b = (_a2 = match[2]) != null ? _a2 : match[3]) != null ? _b : "").toLowerCase();
   const orderedTimings = timing === "c" ? ["c", "ac", "pc"] : timing === "ac" ? ["ac", "c", "pc"] : timing === "pc" ? ["pc", "c", "ac"] : ["c", "ac", "pc"];
   const candidates = orderedTimings.map((token) => `${dose} po ${token}`);
   return collectMatchedCandidates(candidates, limit, matcher);
 }
 function suggestSig(input, options) {
-  var _a, _b;
-  const limit = (_a = options == null ? void 0 : options.limit) != null ? _a : DEFAULT_LIMIT;
+  var _a2, _b;
+  const limit = (_a2 = options == null ? void 0 : options.limit) != null ? _a2 : DEFAULT_LIMIT;
   if (limit <= 0) {
     return [];
   }
@@ -18673,10 +19406,10 @@ function getUnitCategory(unit) {
   return "other";
 }
 function getBaseUnitFactor(unit) {
-  var _a, _b;
+  var _a2, _b;
   if (!unit) return 1;
   const u = unit.toLowerCase();
-  return (_b = (_a = MASS_UNITS[u]) != null ? _a : VOLUME_UNITS[u]) != null ? _b : 1;
+  return (_b = (_a2 = MASS_UNITS[u]) != null ? _a2 : VOLUME_UNITS[u]) != null ? _b : 1;
 }
 function convertValue(value, fromUnit, toUnit, strength) {
   const f = fromUnit.toLowerCase();
@@ -18714,16 +19447,16 @@ function convertValue(value, fromUnit, toUnit, strength) {
 
 // src/utils/strength.ts
 function parseStrength(strength, context) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   const ratio = parseStrengthIntoRatio(strength, context);
   if (!ratio) return {};
-  if (((_a = ratio.denominator) == null ? void 0 : _a.value) === 1 && (((_b = ratio.denominator) == null ? void 0 : _b.unit) === "unit" || !((_c = ratio.denominator) == null ? void 0 : _c.unit))) {
+  if (((_a2 = ratio.denominator) == null ? void 0 : _a2.value) === 1 && (((_b = ratio.denominator) == null ? void 0 : _b.unit) === "unit" || !((_c = ratio.denominator) == null ? void 0 : _c.unit))) {
     return { strengthQuantity: ratio.numerator };
   }
   return { strengthRatio: ratio };
 }
 function parseStrengthIntoRatio(strength, context) {
-  var _a, _b, _c, _d, _e;
+  var _a2, _b, _c, _d, _e;
   const parts = strength.split("+").map((p) => p.trim());
   let totalMgPerMlOrG = 0;
   let hasVolume = false;
@@ -18733,7 +19466,7 @@ function parseStrengthIntoRatio(strength, context) {
   let targetDenValue;
   for (const part of parts) {
     const ratio = parseSingleStrengthPart(part, context);
-    if (!ratio || !((_a = ratio.numerator) == null ? void 0 : _a.value) || ratio.numerator.value === 0) continue;
+    if (!ratio || !((_a2 = ratio.numerator) == null ? void 0 : _a2.value) || ratio.numerator.value === 0) continue;
     const nUnit = ratio.numerator.unit;
     const dUnit = ((_b = ratio.denominator) == null ? void 0 : _b.unit) || "unit";
     const dCat = getUnitCategory(dUnit);
@@ -18808,7 +19541,7 @@ function isSolidDosageForm(form) {
   return false;
 }
 function parseSingleStrengthPart(part, context) {
-  var _a, _b;
+  var _a2, _b;
   const p = part.trim();
   const percentMatch = p.match(/^(\d+(?:\.\d+)?)\s*%$/);
   if (percentMatch) {
@@ -18823,7 +19556,7 @@ function parseSingleStrengthPart(part, context) {
     return {
       numerator: {
         value: parseFloat(ratioMatch[1]),
-        unit: ((_a = ratioMatch[2]) == null ? void 0 : _a.trim()) || "mg"
+        unit: ((_a2 = ratioMatch[2]) == null ? void 0 : _a2.trim()) || "mg"
       },
       denominator: {
         value: ratioMatch[3] ? parseFloat(ratioMatch[3]) : 1,
@@ -18861,6 +19594,7 @@ var DEFAULT_FREQUENCY_DEFAULTS = {
 };
 var SECONDS_PER_MINUTE = 60;
 var MINUTES_PER_DAY = 24 * 60;
+var TOTAL_UNITS_PRECISION = 1e12;
 var dateTimeFormatCache = /* @__PURE__ */ new Map();
 var weekdayFormatCache = /* @__PURE__ */ new Map();
 function pad(value, length = 2) {
@@ -18887,7 +19621,7 @@ function formatToParts(formatter, date) {
   ];
 }
 function normalizeClock(clock) {
-  var _a;
+  var _a2;
   const parts = clock.split(":");
   if (parts.length < 2 || parts.length > 3) {
     throw new Error(`Invalid clock value: ${clock}`);
@@ -18895,7 +19629,7 @@ function normalizeClock(clock) {
   const [hourPart, minutePart, secondPart] = [
     parts[0],
     parts[1],
-    (_a = parts[2]) != null ? _a : "00"
+    (_a2 = parts[2]) != null ? _a2 : "00"
   ];
   const hour = Number(hourPart);
   const minute = Number(minutePart);
@@ -18937,7 +19671,7 @@ function getWeekdayFormat(timeZone) {
   return formatter;
 }
 function getTimeParts(date, timeZone) {
-  var _a, _b;
+  var _a2, _b;
   const formatter = getDateTimeFormat(timeZone);
   const parts = {};
   const rawParts = formatToParts(formatter, date);
@@ -18975,7 +19709,7 @@ function getTimeParts(date, timeZone) {
       }
     }
     parts.hour = 0;
-    parts.minute = (_a = parts.minute) != null ? _a : 0;
+    parts.minute = (_a2 = parts.minute) != null ? _a2 : 0;
     parts.second = (_b = parts.second) != null ? _b : 0;
   }
   if (parts.year === void 0 || parts.month === void 0 || parts.day === void 0 || parts.hour === void 0 || parts.minute === void 0 || parts.second === void 0) {
@@ -19013,10 +19747,10 @@ function makeZonedDate(timeZone, year, month, day, hour, minute, second) {
   return candidate;
 }
 function makeZonedDateFromDay(base, timeZone, clock) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   const { year, month, day } = getTimeParts(base, timeZone);
   const parts = clock.split(":").map((value) => Number(value));
-  const hour = (_a = parts[0]) != null ? _a : 0;
+  const hour = (_a2 = parts[0]) != null ? _a2 : 0;
   const minute = (_b = parts[1]) != null ? _b : 0;
   const second = (_c = parts[2]) != null ? _c : 0;
   return makeZonedDate(timeZone, year, month, day, hour, minute, second);
@@ -19112,6 +19846,49 @@ function coerceDate(value, label) {
   }
   return date;
 }
+function roundCalculatedUnits(value) {
+  if (!Number.isFinite(value)) {
+    return value;
+  }
+  return Math.round((value + Number.EPSILON) * TOTAL_UNITS_PRECISION) / TOTAL_UNITS_PRECISION;
+}
+function resolveContextStrengthRatio(context) {
+  var _a2, _b;
+  if (!context) {
+    return void 0;
+  }
+  return (_b = context.strengthRatio) != null ? _b : context.strength ? (_a2 = parseStrengthIntoRatio(context.strength, context)) != null ? _a2 : void 0 : void 0;
+}
+function estimateIngredientQuantity(quantity, context) {
+  if (quantity.value === void 0 || !quantity.unit) {
+    return void 0;
+  }
+  const strength = resolveContextStrengthRatio(context);
+  const numerator = strength == null ? void 0 : strength.numerator;
+  const denominator = strength == null ? void 0 : strength.denominator;
+  if (!(numerator == null ? void 0 : numerator.unit) || numerator.value === void 0 || !(denominator == null ? void 0 : denominator.unit) || denominator.value === void 0) {
+    return void 0;
+  }
+  const converted = convertValue(
+    quantity.value,
+    quantity.unit,
+    numerator.unit,
+    {
+      numerator: { value: numerator.value, unit: numerator.unit },
+      denominator: { value: denominator.value, unit: denominator.unit }
+    }
+  );
+  if (converted === null) {
+    return void 0;
+  }
+  return {
+    value: roundCalculatedUnits(converted),
+    unit: numerator.unit,
+    confidence: quantity.confidence,
+    basis: quantity.basis,
+    source: quantity.source
+  };
+}
 function applyOffset(clock, offsetMinutes) {
   const [hour, minute, second] = clock.split(":").map((part) => Number(part));
   let totalMinutes = hour * SECONDS_PER_MINUTE + minute + offsetMinutes;
@@ -19132,8 +19909,8 @@ function applyOffset(clock, offsetMinutes) {
   };
 }
 function parseBoundsDurationUnit(quantity) {
-  var _a, _b, _c;
-  const candidate = (_c = (_a = quantity == null ? void 0 : quantity.code) == null ? void 0 : _a.trim().toLowerCase()) != null ? _c : (_b = quantity == null ? void 0 : quantity.unit) == null ? void 0 : _b.trim().toLowerCase();
+  var _a2, _b, _c;
+  const candidate = (_c = (_a2 = quantity == null ? void 0 : quantity.code) == null ? void 0 : _a2.trim().toLowerCase()) != null ? _c : (_b = quantity == null ? void 0 : quantity.unit) == null ? void 0 : _b.trim().toLowerCase();
   switch (candidate) {
     case "s":
     case "sec":
@@ -19175,11 +19952,11 @@ function parseBoundsDurationUnit(quantity) {
   }
 }
 function resolveRepeatBoundsDuration(repeat) {
-  var _a, _b, _c, _d;
+  var _a2, _b, _c, _d;
   if (!repeat) {
     return {};
   }
-  if (((_a = repeat.boundsDuration) == null ? void 0 : _a.value) !== void 0) {
+  if (((_a2 = repeat.boundsDuration) == null ? void 0 : _a2.value) !== void 0) {
     return {
       value: repeat.boundsDuration.value,
       unit: parseBoundsDurationUnit(repeat.boundsDuration)
@@ -19195,9 +19972,9 @@ function resolveRepeatBoundsDuration(repeat) {
   };
 }
 function resolveRepeatDurationCapEnd(repeat, anchor, timeZone) {
-  var _a, _b;
+  var _a2, _b;
   const bounds = resolveRepeatBoundsDuration(repeat);
-  const durationValue = (_a = bounds.max) != null ? _a : bounds.value;
+  const durationValue = (_a2 = bounds.max) != null ? _a2 : bounds.value;
   const durationUnit = bounds.unit;
   if (durationValue === void 0 || !Number.isFinite(durationValue) || durationValue <= 0 || !durationUnit) {
     return null;
@@ -19212,14 +19989,14 @@ function resolveRepeatDurationCapEnd(repeat, anchor, timeZone) {
   return (_b = stepper(anchor)) != null ? _b : null;
 }
 function resolveDayFilteredSeriesRepeat(repeat, enforceDayFilter) {
-  var _a, _b, _c, _d;
+  var _a2, _b, _c, _d;
   if (!enforceDayFilter) {
     return void 0;
   }
   if (repeat.frequency) {
     return void 0;
   }
-  if (((_b = (_a = repeat.when) == null ? void 0 : _a.length) != null ? _b : 0) > 0 || ((_d = (_c = repeat.timeOfDay) == null ? void 0 : _c.length) != null ? _d : 0) > 0) {
+  if (((_b = (_a2 = repeat.when) == null ? void 0 : _a2.length) != null ? _b : 0) > 0 || ((_d = (_c = repeat.timeOfDay) == null ? void 0 : _c.length) != null ? _d : 0) > 0) {
     return void 0;
   }
   switch (repeat.periodUnit) {
@@ -19234,19 +20011,19 @@ function resolveDayFilteredSeriesRepeat(repeat, enforceDayFilter) {
   }
 }
 function isSingleAdministrationRepeat(repeat) {
-  var _a, _b, _c, _d, _e, _f;
-  return repeat.count === 1 && repeat.frequency === void 0 && repeat.frequencyMax === void 0 && repeat.period === void 0 && repeat.periodMax === void 0 && repeat.periodUnit === void 0 && ((_b = (_a = repeat.dayOfWeek) == null ? void 0 : _a.length) != null ? _b : 0) === 0 && ((_d = (_c = repeat.when) == null ? void 0 : _c.length) != null ? _d : 0) === 0 && ((_f = (_e = repeat.timeOfDay) == null ? void 0 : _e.length) != null ? _f : 0) === 0;
+  var _a2, _b, _c, _d, _e, _f;
+  return repeat.count === 1 && repeat.frequency === void 0 && repeat.frequencyMax === void 0 && repeat.period === void 0 && repeat.periodMax === void 0 && repeat.periodUnit === void 0 && ((_b = (_a2 = repeat.dayOfWeek) == null ? void 0 : _a2.length) != null ? _b : 0) === 0 && ((_d = (_c = repeat.when) == null ? void 0 : _c.length) != null ? _d : 0) === 0 && ((_f = (_e = repeat.timeOfDay) == null ? void 0 : _e.length) != null ? _f : 0) === 0;
 }
 function hasUnresolvedRelationalInstruction(dosage) {
-  var _a, _b, _c, _d, _e, _f;
+  var _a2, _b, _c, _d, _e, _f;
   const texts = [];
-  if ((_a = dosage.patientInstruction) == null ? void 0 : _a.trim()) {
+  if ((_a2 = dosage.patientInstruction) == null ? void 0 : _a2.trim()) {
     texts.push(dosage.patientInstruction.trim());
   }
   for (const instruction of (_b = dosage.additionalInstruction) != null ? _b : []) {
     const text = ((_c = instruction.text) == null ? void 0 : _c.trim()) || ((_f = (_e = (_d = instruction.coding) == null ? void 0 : _d.find((coding) => {
-      var _a2;
-      return (_a2 = coding.display) == null ? void 0 : _a2.trim();
+      var _a3;
+      return (_a3 = coding.display) == null ? void 0 : _a3.trim();
     })) == null ? void 0 : _e.display) == null ? void 0 : _f.trim());
     if (text) {
       texts.push(text);
@@ -19288,8 +20065,8 @@ var SPECIFIC_AFTER_MEALS = {
   ["PCV" /* After Dinner */]: "CV" /* Dinner */
 };
 function expandTiming(code, config, repeat) {
-  var _a, _b, _c, _d, _e, _f, _g, _h;
-  const mealOffsets = (_a = config.mealOffsets) != null ? _a : {};
+  var _a2, _b, _c, _d, _e, _f, _g, _h;
+  const mealOffsets = (_a2 = config.mealOffsets) != null ? _a2 : {};
   const eventClock = (_b = config.eventClock) != null ? _b : {};
   const normalized = [];
   const clockValue = eventClock[code];
@@ -19338,8 +20115,8 @@ function expandTiming(code, config, repeat) {
   }
   if (repeat.offset && normalized.length) {
     return normalized.map((entry) => {
-      var _a2;
-      const adjusted = applyOffset(entry.time, (_a2 = repeat.offset) != null ? _a2 : 0);
+      var _a3;
+      const adjusted = applyOffset(entry.time, (_a3 = repeat.offset) != null ? _a3 : 0);
       return {
         time: adjusted.time,
         dayShift: entry.dayShift + adjusted.dayShift
@@ -19404,9 +20181,9 @@ function inferWhenFallbackEntries(whenCodes, repeat) {
   const entries = [];
   const seen = /* @__PURE__ */ new Set();
   const addClock = (clock) => {
-    var _a;
+    var _a2;
     const normalized = normalizeClock(clock);
-    const adjusted = repeat.offset ? applyOffset(normalized, (_a = repeat.offset) != null ? _a : 0) : { time: normalized, dayShift: 0 };
+    const adjusted = repeat.offset ? applyOffset(normalized, (_a2 = repeat.offset) != null ? _a2 : 0) : { time: normalized, dayShift: 0 };
     const key = `${adjusted.dayShift}|${adjusted.time}`;
     if (seen.has(key)) {
       return;
@@ -19434,13 +20211,13 @@ function inferWhenFallbackEntries(whenCodes, repeat) {
   });
 }
 function mergeFrequencyDefaults(base, override) {
-  var _a, _b, _c, _d;
+  var _a2, _b, _c, _d;
   if (!base && !override) {
     return void 0;
   }
   const merged = {};
   if ((base == null ? void 0 : base.byCode) || (override == null ? void 0 : override.byCode)) {
-    merged.byCode = __spreadValues(__spreadValues({}, (_a = base == null ? void 0 : base.byCode) != null ? _a : {}), (_b = override == null ? void 0 : override.byCode) != null ? _b : {});
+    merged.byCode = __spreadValues(__spreadValues({}, (_a2 = base == null ? void 0 : base.byCode) != null ? _a2 : {}), (_b = override == null ? void 0 : override.byCode) != null ? _b : {});
   }
   if ((base == null ? void 0 : base.byFrequency) || (override == null ? void 0 : override.byFrequency)) {
     merged.byFrequency = __spreadValues(__spreadValues({}, (_c = base == null ? void 0 : base.byFrequency) != null ? _c : {}), (_d = override == null ? void 0 : override.byFrequency) != null ? _d : {});
@@ -19467,9 +20244,9 @@ function inferDailyFrequencyClocks(frequency) {
   return Array.from(clocks).sort();
 }
 function resolveFrequencyClocks(timing, config) {
-  var _a, _b, _c, _d, _e, _f, _g, _h, _i, _j;
+  var _a2, _b, _c, _d, _e, _f, _g, _h, _i, _j;
   const defaults = {
-    byCode: __spreadValues(__spreadValues({}, DEFAULT_FREQUENCY_DEFAULTS.byCode), (_b = (_a = config.frequencyDefaults) == null ? void 0 : _a.byCode) != null ? _b : {}),
+    byCode: __spreadValues(__spreadValues({}, DEFAULT_FREQUENCY_DEFAULTS.byCode), (_b = (_a2 = config.frequencyDefaults) == null ? void 0 : _a2.byCode) != null ? _b : {}),
     byFrequency: __spreadValues(__spreadValues({}, DEFAULT_FREQUENCY_DEFAULTS.byFrequency), (_d = (_c = config.frequencyDefaults) == null ? void 0 : _c.byFrequency) != null ? _d : {})
   };
   const collected = /* @__PURE__ */ new Set();
@@ -19503,14 +20280,14 @@ function resolveFrequencyClocks(timing, config) {
   return Array.from(collected).sort();
 }
 function nextDueDoses(dosage, options) {
-  var _a, _b, _c, _d, _e, _f, _g, _h, _i;
+  var _a2, _b, _c, _d, _e, _f, _g, _h, _i;
   if (!options || typeof options !== "object") {
     throw new Error("Options argument is required for nextDueDoses");
   }
   if (options.from === void 0) {
     throw new Error("The 'from' option is required for nextDueDoses");
   }
-  const limit = (_a = options.limit) != null ? _a : 10;
+  const limit = (_a2 = options.limit) != null ? _a2 : 10;
   if (!Number.isFinite(limit) || limit <= 0) {
     return [];
   }
@@ -19739,7 +20516,7 @@ function nextDueDoses(dosage, options) {
   return [];
 }
 function derivePriorCountFromHistory(timing, repeat, config, orderedAt, from, timeZone) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   if (from <= orderedAt) {
     return 0;
   }
@@ -19747,7 +20524,7 @@ function derivePriorCountFromHistory(timing, repeat, config, orderedAt, from, ti
   if (normalizedCount === 0) {
     return 0;
   }
-  const dayFilter = new Set(((_a = repeat.dayOfWeek) != null ? _a : []).map((day) => day.toLowerCase()));
+  const dayFilter = new Set(((_a2 = repeat.dayOfWeek) != null ? _a2 : []).map((day) => day.toLowerCase()));
   const enforceDayFilter = dayFilter.size > 0;
   const dayFilteredSeriesRepeat = resolveDayFilteredSeriesRepeat(repeat, enforceDayFilter);
   const seen = /* @__PURE__ */ new Set();
@@ -20091,7 +20868,7 @@ function toLocalClock(date, timeZone) {
   return `${h}:${m}:${s}`;
 }
 function countScheduleEvents(dosage, from, to, config, baseTime, orderedAt, limit) {
-  var _a, _b, _c;
+  var _a2, _b, _c;
   const timing = dosage.timing;
   const repeat = timing == null ? void 0 : timing.repeat;
   if (!timing || !repeat) return 0;
@@ -20099,7 +20876,7 @@ function countScheduleEvents(dosage, from, to, config, baseTime, orderedAt, limi
   if (normalizedCount === 0) {
     return 0;
   }
-  const dayFilter = new Set(((_a = repeat.dayOfWeek) != null ? _a : []).map((day) => day.toLowerCase()));
+  const dayFilter = new Set(((_a2 = repeat.dayOfWeek) != null ? _a2 : []).map((day) => day.toLowerCase()));
   const enforceDayFilter = dayFilter.size > 0;
   const dayFilteredSeriesRepeat = resolveDayFilteredSeriesRepeat(repeat, enforceDayFilter);
   const seen = /* @__PURE__ */ new Set();
@@ -20238,12 +21015,12 @@ function countScheduleEvents(dosage, from, to, config, baseTime, orderedAt, limi
   return count;
 }
 function calculateTotalUnitsSingle(options) {
-  var _a, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m;
+  var _a2, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n;
   const { dosage, durationValue, durationUnit, roundToMultiple, context } = options;
   const from = coerceDate(options.from, "from");
   const orderedAtDate = options.orderedAt === void 0 ? null : coerceDate(options.orderedAt, "orderedAt");
   const providedConfig = options.config;
-  const timeZone = (_a = options.timeZone) != null ? _a : providedConfig == null ? void 0 : providedConfig.timeZone;
+  const timeZone = (_a2 = options.timeZone) != null ? _a2 : providedConfig == null ? void 0 : providedConfig.timeZone;
   if (!timeZone) {
     throw new Error("timeZone is required for calculateTotalUnits");
   }
@@ -20281,31 +21058,61 @@ function calculateTotalUnitsSingle(options) {
     2e3
   );
   const doseQuantity = (_j = (_i = (_h = (_g = dosage.doseAndRate) == null ? void 0 : _g[0]) == null ? void 0 : _h.doseQuantity) == null ? void 0 : _i.value) != null ? _j : 0;
-  let totalUnits = count * doseQuantity;
+  let totalUnits = roundCalculatedUnits(count * doseQuantity);
   if (roundToMultiple && roundToMultiple > 0) {
-    totalUnits = Math.ceil(totalUnits / roundToMultiple) * roundToMultiple;
+    totalUnits = roundCalculatedUnits(Math.ceil(totalUnits / roundToMultiple) * roundToMultiple);
   }
   const result = { totalUnits };
   const containerValue = context == null ? void 0 : context.containerValue;
   const containerUnit = context == null ? void 0 : context.containerUnit;
+  const packageUnit = context == null ? void 0 : context.packageUnit;
   const doseUnit = (_m = (_l = (_k = dosage.doseAndRate) == null ? void 0 : _k[0]) == null ? void 0 : _l.doseQuantity) == null ? void 0 : _m.unit;
+  const unitSemantics = getDoseUnitSemantics(doseUnit, context);
+  if (unitSemantics == null ? void 0 : unitSemantics.approximateQuantity) {
+    const approximation = unitSemantics.approximateQuantity;
+    result.totalApproximateQuantity = {
+      value: roundCalculatedUnits(totalUnits * approximation.value),
+      unit: approximation.unit,
+      confidence: approximation.confidence,
+      basis: approximation.basis,
+      source: approximation.source
+    };
+    result.totalApproximateIngredientQuantity = estimateIngredientQuantity(
+      result.totalApproximateQuantity,
+      context
+    );
+  }
   if (containerValue && containerValue > 0) {
     let effectiveUnits = totalUnits;
-    if (containerUnit && doseUnit && containerUnit !== doseUnit) {
-      let strength = context == null ? void 0 : context.strengthRatio;
-      if (!strength && (context == null ? void 0 : context.strength)) {
-        strength = parseStrengthIntoRatio(context.strength, context) || void 0;
+    let effectiveContainerValue = containerValue;
+    if (containerUnit && ((_n = result.totalApproximateQuantity) == null ? void 0 : _n.unit) && result.totalApproximateQuantity.value !== void 0 && result.totalApproximateQuantity.unit.trim().toLowerCase() === containerUnit.trim().toLowerCase()) {
+      effectiveUnits = result.totalApproximateQuantity.value;
+      result.totalContainerQuantity = {
+        value: result.totalApproximateQuantity.value,
+        unit: containerUnit
+      };
+    } else if (packageUnit && doseUnit && doseUnit.trim().toLowerCase() === packageUnit.trim().toLowerCase()) {
+      effectiveUnits = totalUnits;
+      effectiveContainerValue = 1;
+      if (containerUnit) {
+        result.totalContainerQuantity = {
+          value: roundCalculatedUnits(totalUnits * containerValue),
+          unit: containerUnit
+        };
       }
+    } else if (containerUnit && doseUnit && containerUnit !== doseUnit) {
+      const strength = resolveContextStrengthRatio(context);
       const converted = convertValue(totalUnits, doseUnit, containerUnit, strength);
       if (converted !== null) {
         effectiveUnits = converted;
       }
     }
-    result.totalContainers = Math.ceil(effectiveUnits / containerValue);
+    result.totalContainers = Math.ceil(effectiveUnits / effectiveContainerValue);
   }
   return result;
 }
 function calculateTotalUnits(options) {
+  var _a2, _b, _c, _d, _e, _f;
   if (Array.isArray(options.dosage)) {
     const hasAnyDosage = options.dosage.length > 0;
     if (!hasAnyDosage) {
@@ -20313,18 +21120,62 @@ function calculateTotalUnits(options) {
     }
     let totalUnits = 0;
     let totalContainers = 0;
+    let totalContainerQuantity;
+    let totalApproximateQuantity;
+    let totalApproximateIngredientQuantity;
+    let mixedTotalContainerQuantities = false;
+    let mixedApproximateQuantities = false;
+    let mixedApproximateIngredientQuantities = false;
     let sawContainers = false;
     for (const dosage of options.dosage) {
       const result = calculateTotalUnitsSingle(__spreadProps(__spreadValues({}, options), {
         dosage
       }));
-      totalUnits += result.totalUnits;
+      totalUnits = roundCalculatedUnits(totalUnits + result.totalUnits);
+      if (result.totalApproximateQuantity && !mixedApproximateQuantities) {
+        if (totalApproximateQuantity && totalApproximateQuantity.unit === result.totalApproximateQuantity.unit && totalApproximateQuantity.confidence === result.totalApproximateQuantity.confidence && totalApproximateQuantity.basis === result.totalApproximateQuantity.basis && totalApproximateQuantity.source === result.totalApproximateQuantity.source) {
+          totalApproximateQuantity.value = roundCalculatedUnits(
+            ((_a2 = totalApproximateQuantity.value) != null ? _a2 : 0) + ((_b = result.totalApproximateQuantity.value) != null ? _b : 0)
+          );
+        } else if (!totalApproximateQuantity) {
+          totalApproximateQuantity = __spreadValues({}, result.totalApproximateQuantity);
+        } else {
+          totalApproximateQuantity = void 0;
+          mixedApproximateQuantities = true;
+        }
+      }
+      if (result.totalApproximateIngredientQuantity && !mixedApproximateIngredientQuantities) {
+        if (totalApproximateIngredientQuantity && totalApproximateIngredientQuantity.unit === result.totalApproximateIngredientQuantity.unit && totalApproximateIngredientQuantity.confidence === result.totalApproximateIngredientQuantity.confidence && totalApproximateIngredientQuantity.basis === result.totalApproximateIngredientQuantity.basis && totalApproximateIngredientQuantity.source === result.totalApproximateIngredientQuantity.source) {
+          totalApproximateIngredientQuantity.value = roundCalculatedUnits(
+            ((_c = totalApproximateIngredientQuantity.value) != null ? _c : 0) + ((_d = result.totalApproximateIngredientQuantity.value) != null ? _d : 0)
+          );
+        } else if (!totalApproximateIngredientQuantity) {
+          totalApproximateIngredientQuantity = __spreadValues({}, result.totalApproximateIngredientQuantity);
+        } else {
+          totalApproximateIngredientQuantity = void 0;
+          mixedApproximateIngredientQuantities = true;
+        }
+      }
       if (result.totalContainers !== void 0) {
         totalContainers += result.totalContainers;
         sawContainers = true;
       }
+      if (result.totalContainerQuantity && !mixedTotalContainerQuantities) {
+        if (totalContainerQuantity && totalContainerQuantity.unit === result.totalContainerQuantity.unit && totalContainerQuantity.system === result.totalContainerQuantity.system && totalContainerQuantity.code === result.totalContainerQuantity.code) {
+          totalContainerQuantity.value = roundCalculatedUnits(
+            ((_e = totalContainerQuantity.value) != null ? _e : 0) + ((_f = result.totalContainerQuantity.value) != null ? _f : 0)
+          );
+        } else if (!totalContainerQuantity) {
+          totalContainerQuantity = __spreadValues({}, result.totalContainerQuantity);
+        } else {
+          totalContainerQuantity = void 0;
+          mixedTotalContainerQuantities = true;
+        }
+      }
     }
-    return sawContainers ? { totalUnits, totalContainers } : { totalUnits };
+    return __spreadValues(__spreadValues(__spreadValues(__spreadValues({
+      totalUnits
+    }, sawContainers ? { totalContainers } : {}), !mixedTotalContainerQuantities && totalContainerQuantity ? { totalContainerQuantity } : {}), !mixedApproximateQuantities && totalApproximateQuantity ? { totalApproximateQuantity } : {}), !mixedApproximateIngredientQuantities && totalApproximateIngredientQuantity ? { totalApproximateIngredientQuantity } : {});
   }
   return calculateTotalUnitsSingle(options);
 }
@@ -20525,8 +21376,8 @@ function uniqueStrings(values) {
   return output;
 }
 function mergeParseResults(base, next, options) {
-  var _a, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n, _o, _p, _q;
-  const baseRepeat = (_b = (_a = base.fhir.timing) == null ? void 0 : _a.repeat) != null ? _b : {};
+  var _a2, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n, _o, _p, _q;
+  const baseRepeat = (_b = (_a2 = base.fhir.timing) == null ? void 0 : _a2.repeat) != null ? _b : {};
   const nextRepeat = (_d = (_c = next.fhir.timing) == null ? void 0 : _c.repeat) != null ? _d : {};
   const mergedWhen = uniqueStrings([...(_e = baseRepeat.when) != null ? _e : [], ...(_f = nextRepeat.when) != null ? _f : []]);
   const mergedTimeOfDay = uniqueStrings([...(_g = baseRepeat.timeOfDay) != null ? _g : [], ...(_h = nextRepeat.timeOfDay) != null ? _h : []]).sort();
@@ -20685,8 +21536,8 @@ function formatSig(dosage, style = "short", options) {
   return formatCanonicalClause(clause, style, localization, options);
 }
 function formatSigBatch(dosages, style = "short", options) {
-  var _a;
-  const separator = (_a = options == null ? void 0 : options.separator) != null ? _a : ", ";
+  var _a2;
+  const separator = (_a2 = options == null ? void 0 : options.separator) != null ? _a2 : ", ";
   const formatted = [];
   for (const dosage of dosages) {
     const text = formatSig(dosage, style, options);
@@ -20701,7 +21552,7 @@ function formatParseBatch(batch, style = "short", separator = ", ") {
   return texts.join(separator);
 }
 function fromFhirDosage(dosage, options) {
-  var _a;
+  var _a2;
   const clause = canonicalFromFhir(dosage);
   const localization = resolveSigLocalization(options == null ? void 0 : options.locale, options == null ? void 0 : options.i18n);
   const shortText = formatCanonicalClause(clause, "short", localization, options);
@@ -20712,10 +21563,10 @@ function fromFhirDosage(dosage, options) {
     fhir: dosage,
     shortText,
     longText,
-    warnings: (_a = clause.warnings) != null ? _a : [],
+    warnings: (_a2 = clause.warnings) != null ? _a2 : [],
     meta: {
       consumedTokens: [],
-      normalized: buildNormalizedMetaFromClause(clause, dosage),
+      normalized: buildNormalizedMetaFromClause(clause, dosage, options),
       canonical: {
         clauses: [clause]
       }
@@ -20737,8 +21588,8 @@ function createEmptyCanonicalClause2(rawText) {
   };
 }
 function getPrimaryClause(clauses, rawText) {
-  var _a;
-  return (_a = clauses[0]) != null ? _a : createEmptyCanonicalClause2(rawText);
+  var _a2;
+  return (_a2 = clauses[0]) != null ? _a2 : createEmptyCanonicalClause2(rawText);
 }
 function cloneCoding2(coding) {
   if (!(coding == null ? void 0 : coding.code) && !(coding == null ? void 0 : coding.display) && !(coding == null ? void 0 : coding.system)) {
@@ -20761,32 +21612,36 @@ function cloneBodySiteCoding2(coding) {
     system: coding.system
   };
 }
-function buildNormalizedMetaFromClause(clause, fhir) {
-  var _a, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n, _o, _p, _q, _r, _s, _t, _u, _v, _w, _x, _y, _z, _A, _B, _C, _D, _E;
-  const additionalInstructions = ((_a = clause.additionalInstructions) == null ? void 0 : _a.length) ? clause.additionalInstructions.map((instruction) => ({
+function buildNormalizedMetaFromClause(clause, fhir, options) {
+  var _a2, _b, _c, _d, _e, _f, _g, _h, _i, _j, _k, _l, _m, _n, _o, _p, _q, _r, _s, _t, _u, _v, _w, _x, _y, _z, _A, _B, _C, _D, _E, _F;
+  const additionalInstructions = ((_a2 = clause.additionalInstructions) == null ? void 0 : _a2.length) ? clause.additionalInstructions.map((instruction) => ({
     text: instruction.text,
     coding: cloneCoding2(instruction.coding)
   })) : void 0;
   const siteCoding = (_e = cloneBodySiteCoding2((_b = clause.site) == null ? void 0 : _b.coding)) != null ? _e : cloneBodySiteCoding2((_d = (_c = fhir == null ? void 0 : fhir.site) == null ? void 0 : _c.coding) == null ? void 0 : _d[0]);
+  const parseContext = options && "context" in options ? options.context : void 0;
+  const unitSemantics = getDoseUnitSemantics((_f = clause.dose) == null ? void 0 : _f.unit, parseContext);
   return {
-    route: (_f = clause.route) == null ? void 0 : _f.code,
-    unit: (_g = clause.dose) == null ? void 0 : _g.unit,
-    site: ((_h = clause.site) == null ? void 0 : _h.text) || ((_j = (_i = clause.site) == null ? void 0 : _i.coding) == null ? void 0 : _j.code) || ((_k = clause.site) == null ? void 0 : _k.spatialRelation) ? {
-      text: (_l = clause.site) == null ? void 0 : _l.text,
+    route: (_g = clause.route) == null ? void 0 : _g.code,
+    unit: (_h = clause.dose) == null ? void 0 : _h.unit,
+    unitKind: unitSemantics == null ? void 0 : unitSemantics.kind,
+    unitSemantics,
+    site: ((_i = clause.site) == null ? void 0 : _i.text) || ((_k = (_j = clause.site) == null ? void 0 : _j.coding) == null ? void 0 : _k.code) || ((_l = clause.site) == null ? void 0 : _l.spatialRelation) ? {
+      text: (_m = clause.site) == null ? void 0 : _m.text,
       coding: siteCoding,
-      spatialRelation: cloneBodySiteSpatialRelation((_m = clause.site) == null ? void 0 : _m.spatialRelation)
+      spatialRelation: cloneBodySiteSpatialRelation((_n = clause.site) == null ? void 0 : _n.spatialRelation)
     } : void 0,
-    method: ((_n = clause.method) == null ? void 0 : _n.text) || ((_p = (_o = clause.method) == null ? void 0 : _o.coding) == null ? void 0 : _p.code) ? {
-      text: (_q = clause.method) == null ? void 0 : _q.text,
-      coding: cloneCoding2((_r = clause.method) == null ? void 0 : _r.coding)
+    method: ((_o = clause.method) == null ? void 0 : _o.text) || ((_q = (_p = clause.method) == null ? void 0 : _p.coding) == null ? void 0 : _q.code) ? {
+      text: (_r = clause.method) == null ? void 0 : _r.text,
+      coding: cloneCoding2((_s = clause.method) == null ? void 0 : _s.coding)
     } : void 0,
     patientInstruction: clause.patientInstruction,
-    prnReason: ((_t = (_s = clause.prn) == null ? void 0 : _s.reason) == null ? void 0 : _t.text) || ((_w = (_v = (_u = clause.prn) == null ? void 0 : _u.reason) == null ? void 0 : _v.coding) == null ? void 0 : _w.code) ? {
-      text: (_y = (_x = clause.prn) == null ? void 0 : _x.reason) == null ? void 0 : _y.text,
-      coding: cloneCoding2((_A = (_z = clause.prn) == null ? void 0 : _z.reason) == null ? void 0 : _A.coding),
-      spatialRelation: cloneBodySiteSpatialRelation((_C = (_B = clause.prn) == null ? void 0 : _B.reason) == null ? void 0 : _C.spatialRelation)
+    prnReason: ((_u = (_t = clause.prn) == null ? void 0 : _t.reason) == null ? void 0 : _u.text) || ((_x = (_w = (_v = clause.prn) == null ? void 0 : _v.reason) == null ? void 0 : _w.coding) == null ? void 0 : _x.code) ? {
+      text: (_z = (_y = clause.prn) == null ? void 0 : _y.reason) == null ? void 0 : _z.text,
+      coding: cloneCoding2((_B = (_A = clause.prn) == null ? void 0 : _A.reason) == null ? void 0 : _B.coding),
+      spatialRelation: cloneBodySiteSpatialRelation((_D = (_C = clause.prn) == null ? void 0 : _C.reason) == null ? void 0 : _D.spatialRelation)
     } : void 0,
-    prnReasons: ((_E = (_D = clause.prn) == null ? void 0 : _D.reasons) == null ? void 0 : _E.length) ? clause.prn.reasons.map((reason) => ({
+    prnReasons: ((_F = (_E = clause.prn) == null ? void 0 : _E.reasons) == null ? void 0 : _F.length) ? clause.prn.reasons.map((reason) => ({
       text: reason.text,
       coding: cloneCoding2(reason.coding),
       spatialRelation: cloneBodySiteSpatialRelation(reason.spatialRelation)
@@ -20856,7 +21711,7 @@ function buildParseResult(state, options) {
     meta: {
       consumedTokens,
       leftoverText: leftoverParts.length ? leftoverParts.join(" ") : void 0,
-      normalized: buildNormalizedMetaFromClause(clause, fhir),
+      normalized: buildNormalizedMetaFromClause(clause, fhir, options),
       canonical: {
         clauses: canonicalClauses
       },
@@ -20936,10 +21791,10 @@ function resolvePrimaryParseResult(results, input, options) {
   return buildParseResult(state, options);
 }
 function buildSemanticLintIssues(result, input, fallbackRange) {
-  var _a;
+  var _a2;
   const issues = [];
   const clause = result.meta.canonical.clauses[0];
-  const range = (_a = clause == null ? void 0 : clause.span) != null ? _a : fallbackRange;
+  const range = (_a2 = clause == null ? void 0 : clause.span) != null ? _a2 : fallbackRange;
   const text = range ? input.slice(range.start, range.end) : input;
   const trimmedText = text.trim() || text;
   const tokens = trimmedText ? trimmedText.split(/\s+/).filter((part) => part.length > 0) : [];
@@ -21025,11 +21880,15 @@ function resolvePrimaryLintResult(results, input, options) {
   getBodySiteCodeAsync,
   getBodySiteText,
   getBodySiteTextAsync,
+  getDoseUnitApproximation,
+  getDoseUnitKind,
+  getDoseUnitSemantics,
   getRegisteredSigLocalizations,
   hasSnomedBodySiteLateralityPostcoordination,
   hasSnomedFindingSitePostcoordination,
   hasSnomedTopographicalModifierPostcoordination,
   lintSig,
+  listDoseUnitTerminology,
   listSupportedBodySiteGrammar,
   listSupportedBodySiteText,
   lookupBodySite,